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Search of human proteins with 60460889
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|60460889 Myb protein P42POP [Homo sapiens]
(399 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|60460889 Myb protein P42POP [Homo sapiens] 823 0.0
gi|160707881 formin 2 [Homo sapiens] 91 2e-18
gi|47132519 Ras association and pleckstrin homology domains 1 is... 89 9e-18
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 86 5e-17
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 86 6e-17
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 86 6e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 9e-16
gi|11386183 WAS protein family, member 2 [Homo sapiens] 82 1e-15
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 80 3e-15
gi|40353727 synaptopodin isoform A [Homo sapiens] 79 6e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 79 9e-15
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 79 9e-15
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 78 2e-14
gi|18959210 WIRE protein [Homo sapiens] 77 2e-14
gi|7706501 WW domain binding protein 11 [Homo sapiens] 77 2e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 77 3e-14
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 77 4e-14
gi|33356148 formin-like 1 [Homo sapiens] 76 5e-14
gi|153792074 proline rich 12 [Homo sapiens] 76 5e-14
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 74 2e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 74 2e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 74 3e-13
gi|150378539 piccolo isoform 1 [Homo sapiens] 74 3e-13
gi|210032580 SET domain containing 1B [Homo sapiens] 74 3e-13
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 74 3e-13
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 73 4e-13
gi|33286436 gametogenetin [Homo sapiens] 72 1e-12
gi|150417989 cyclin K isoform 1 [Homo sapiens] 71 2e-12
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 71 2e-12
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 71 2e-12
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 823 bits (2126), Expect = 0.0
Identities = 399/399 (100%), Positives = 399/399 (100%)
Query: 1 MASAAAGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIA 60
MASAAAGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIA
Sbjct: 1 MASAAAGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIA 60
Query: 61 AKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAIL 120
AKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAIL
Sbjct: 61 AKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAIL 120
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE 180
GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE
Sbjct: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE 180
Query: 181 PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSP 240
PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSP
Sbjct: 181 PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSP 240
Query: 241 PSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPG 300
PSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPG
Sbjct: 241 PSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPG 300
Query: 301 TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR 360
TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR
Sbjct: 301 TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR 360
Query: 361 SEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
SEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP
Sbjct: 361 SEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 90.5 bits (223), Expect = 2e-18
Identities = 91/298 (30%), Positives = 104/298 (34%), Gaps = 86/298 (28%)
Query: 118 AILGPGVAAPGA---------GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADT 168
A + P PGA GAG PP P + PPP P
Sbjct: 951 AAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP----------------- 993
Query: 169 SAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAP--P 226
AG P P P P P PP P LP + PPPP P
Sbjct: 994 ----GAGIPPPPPLPGAGIPP-----PPPLPGAGIPP----PPPLPGAGIPPPPPLPGAG 1040
Query: 227 LPPPPPL--AQVAPSPP-----SPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGT 279
+PPPPPL A + P PP PPPPP P + P L G
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-----------------LPGA 1083
Query: 280 LRQGLAKLSEALSALLPLLPGTPVDSLPPP-------LPPPPP------PPPPPRPVL-- 324
G+ A +P P P +PPP +PPPPP PPPPP P
Sbjct: 1084 ---GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
Query: 325 --PPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
PPP P+V I P P A + + G I P G PPP PLP PP
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGVGIPPPPPLPGVGIPP 1197
Score = 89.4 bits (220), Expect = 5e-18
Identities = 88/285 (30%), Positives = 99/285 (34%), Gaps = 76/285 (26%)
Query: 127 PGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPS 186
P GAG PP P + PPP P AG P P
Sbjct: 936 PLPGAGIPPPPPLPGAAIPPPPPLPG---------------------AGIPLPPPLPGAG 974
Query: 187 CTPQEGGCPRPKERESPPP-----SALQPVQLPRLALSPPPPAPP--LPPPPPL--AQVA 237
P P P PPP P LP + PPPP P +PPPPPL A +
Sbjct: 975 IPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1031
Query: 238 PSPPSP-----PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALS 292
P PP P PPPP P + P L G G+
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPP-----------------LPGA---GIPPPPPLPG 1071
Query: 293 ALLPLLPGTPVDSLPPP-------LPPPPP------PPPPPRPVL----PPPAPKVEITP 335
A +P P P +PPP +PPPPP PPPPP P PPP P I P
Sbjct: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP 1131
Query: 336 EPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
P A + + G I P GA PPP PLP PP
Sbjct: 1132 PPPLPGAGIPPPPPLPRVG-IPPPPPLPGAGIPPPPPLPGAGIPP 1175
Score = 89.4 bits (220), Expect = 5e-18
Identities = 89/295 (30%), Positives = 103/295 (34%), Gaps = 79/295 (26%)
Query: 121 GPGVAAPGA--GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSS 178
G G+ P GAG PP P + PPP P AG
Sbjct: 994 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG---------------------AGIPP 1032
Query: 179 PEPWARPSCTPQEGGCPRPKERESPPP-----SALQPVQLPRLALSPPPPAPP--LPPPP 231
P P P P P PPP P LP + PPPP P +PPPP
Sbjct: 1033 PPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
Query: 232 PL--AQVAPSPPSP-----PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGL 284
PL A + P PP P PPPP P + P L G G+
Sbjct: 1090 PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP-----------------LPGA---GI 1129
Query: 285 AKLSEALSALLPLLPGTPVDSLPPP-------LPPPPP------PPPPPRPVL----PPP 327
A +P P P +PPP +PPPPP PPPPP P + PPP
Sbjct: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189
Query: 328 APKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRP--PPAPLPPHDSPP 380
P V I P P A + + G+ AP P PP PL P PP
Sbjct: 1190 LPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Score = 87.8 bits (216), Expect = 2e-17
Identities = 91/292 (31%), Positives = 101/292 (34%), Gaps = 87/292 (29%)
Query: 121 GPGVAAPGA--GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSS 178
G G+ P GAG PP P + PPP P AG
Sbjct: 983 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG---------------------AGIPP 1021
Query: 179 PEPWARPSCTPQEGGCPRPKERESPPP-----SALQPVQLPRLALSPPPPAPP--LPPPP 231
P P P P P PPP P LP + PPPP P +PPPP
Sbjct: 1022 PPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078
Query: 232 PL--AQVAPSPPSPP---PPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAK 286
PL A + P PP P PPP P P + P L G G+
Sbjct: 1079 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP---------------PLPGA---GIPP 1120
Query: 287 LSEALSALLPLLPGTPVDSLPPP-------LPPPPP------PPPPPRPVL----PPPAP 329
A +P P P +PPP +PPPPP PPPPP P PPP P
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180
Query: 330 KVEITPEPVSVVAAVVDGAVVAARGVIIAPRSE-EGAPRPPPAPLPPHDSPP 380
V I P P GV I P GA PPP PLP PP
Sbjct: 1181 GVGIPPPP-------------PLPGVGIPPPPPLPGAGIPPPPPLPGMGIPP 1219
Score = 85.5 bits (210), Expect = 8e-17
Identities = 95/314 (30%), Positives = 108/314 (34%), Gaps = 91/314 (28%)
Query: 122 PGVAAPGA----GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS 177
PG A P GAG PP P + PPP P AG
Sbjct: 949 PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPG---------------------AGIP 987
Query: 178 SPEPWARPSCTPQEGGCPRPKERESPPP-----SALQPVQLPRLALSPPPPAPP--LPPP 230
P P P P P PPP P LP + PPPP P +PPP
Sbjct: 988 PPPPLPGAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
Query: 231 PPL--AQVAPSPPSP-----PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQG 283
PPL A + P PP P PPPP P + P L G G
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-----------------LPGA---G 1084
Query: 284 LAKLSEALSALLPLLPGTPVDSLPPP-------LPPPPP------PPPPPRPVL----PP 326
+ A +P P P +PPP +PPPPP PPPPP P PP
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1144
Query: 327 PAPKVEITPEPVSVVAAV-----VDGAVVAAR----GVIIAPRSE---EGAPRPPPAPLP 374
P P+V I P P A + + GA + GV I P G P PPP P
Sbjct: 1145 PLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGA 1204
Query: 375 PHDSPPHKRRKGFP 388
PP G P
Sbjct: 1205 GIPPPPPLPGMGIP 1218
Score = 84.7 bits (208), Expect = 1e-16
Identities = 90/288 (31%), Positives = 105/288 (36%), Gaps = 62/288 (21%)
Query: 133 AEEPPAAPSSQPPPPSAC-----------PQRYVLSEDRREDRRADTSAHSKAGSSSPEP 181
+ +P + S PPPPS P + +E + + +SA K + P P
Sbjct: 800 SHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAF-KNSCNIPSP 858
Query: 182 WARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPL-------PPPPPLA 234
P CT P PPP L + +P L + P PPL PPPPPL
Sbjct: 859 PPLP-CTESSSSMPG-LGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL- 915
Query: 235 QVAPSPPSPPPPPRP-------PPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKL 287
P PPPPP P PP A P L G L
Sbjct: 916 ---PGAGIPPPPPLPGAGILPLPPLPGAGIPPPP-------------PLPGAAIPPPPPL 959
Query: 288 SEALSALLPLLPGTPVDSLPPPLP----PPPP-------PPPPPRPVL----PPPAPKVE 332
A L P LPG + PPPLP PPPP PPPPP P PPP P
Sbjct: 960 PGAGIPLPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1018
Query: 333 ITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
I P P A + + G I P GA PPP PLP PP
Sbjct: 1019 IPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPP 1065
Score = 79.0 bits (193), Expect = 7e-15
Identities = 86/282 (30%), Positives = 97/282 (34%), Gaps = 71/282 (25%)
Query: 127 PGAGAGAEEPPAAPSSQPP--PPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWAR 184
PG G PP P P P +A PQ L + P P
Sbjct: 871 PGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPL----------------QGTEMLPPP--- 911
Query: 185 PSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAP--PLPPPPPLAQVA-PSPP 241
P P G P P P L LP + PPPP P +PPPPPL P PP
Sbjct: 912 PPPLPGAGIPPPPP---LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
Query: 242 S------PPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALL 295
PPPPP P + P L G G+ A +
Sbjct: 969 PLPGAGIPPPPPLPGAGIPPPPP-----------------LPGA---GIPPPPPLPGAGI 1008
Query: 296 PLLPGTPVDSLPPP-------LPPPPP------PPPPPRPVL----PPPAPKVEITPEPV 338
P P P +PPP +PPPPP PPPPP P PPP P I P P
Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1068
Query: 339 SVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
A + + G I P GA PPP PLP PP
Sbjct: 1069 LPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGVGIPP 1109
Score = 71.2 bits (173), Expect = 2e-12
Identities = 71/242 (29%), Positives = 86/242 (35%), Gaps = 69/242 (28%)
Query: 121 GPGVAAPGA--GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSS 178
G G+ P GAG PP P + PPP P G+
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-----------------------GAGI 1085
Query: 179 PEPWARPSCTPQEGGCPRPKERES---PPPSALQ------PVQLPRLALSPPPPAPP--L 227
P P P G P P PPP L P LP + PPPP P +
Sbjct: 1086 PPPPPLPGA-----GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
Query: 228 PPPPPLAQVAPSPPSPPPP---PRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGL 284
PPPPPL +V PP P P P PPP A P L G G+
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-------------PLPGV---GI 1184
Query: 285 AKLSEALSALLPLLPGTPVDSLPPP-------LPPPPPPP-PPPRPVLPPPAPKVEITPE 336
+P P P +PPP +PP P PP PPP +PPP P + ++
Sbjct: 1185 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP-PLLPVSGP 1243
Query: 337 PV 338
P+
Sbjct: 1244 PL 1245
Score = 66.6 bits (161), Expect = 4e-11
Identities = 72/246 (29%), Positives = 82/246 (33%), Gaps = 77/246 (31%)
Query: 121 GPGVAAPGA--GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSS 178
G G+ P GAG PP P + PPP P AG
Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG---------------------AGIPP 1098
Query: 179 PEPWARPSCTPQE----GGCPRPKERES---PPPSALQ------PVQLPRLALSPPPPAP 225
P P P G P P PPP L P LPR+ + PPPP P
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 226 P--LPPPPPL--AQVAPSPPSPP---PPPRPPPTLSASDPSLDFLRAQQETANAIRELAG 278
+PPPPPL A + P PP P PPP P P + P
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP------------------- 1199
Query: 279 TLRQGLAKLSEALSALLPLLPG-----TPVDSLPPP---LPPPPPPPPPPRPVLPPPAPK 330
L A P LPG P LPPP +PPPP P P+LP
Sbjct: 1200 -------PLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSS 1252
Query: 331 VEITPE 336
TP+
Sbjct: 1253 TLPTPQ 1258
Score = 36.2 bits (82), Expect = 0.054
Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 20/129 (15%)
Query: 132 GAEEPPAAPSSQPPPPSAC--PQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTP 189
GAEEP A P++ P P A R++L A GS E
Sbjct: 228 GAEEPAAPPTAVSPQPGAFLGLDRFLLG--------PSGGAGEAPGSPDTEQALSALSDL 279
Query: 190 QEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRP 249
E P+E + PP PV AP LP P A+ +PS + P P
Sbjct: 280 PESLAAEPREPQQPPSPGGLPVS----------EAPSLPAAQPAAKDSPSSTAFPFPEAG 329
Query: 250 PPTLSASDP 258
P +A P
Sbjct: 330 PGEEAAGAP 338
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 88.6 bits (218), Expect = 9e-18
Identities = 64/198 (32%), Positives = 77/198 (38%), Gaps = 32/198 (16%)
Query: 196 RPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSA 255
RP PP S + P A P PP PP PPPPP PP PPPPP PPP S
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPP-------PPPPPPPPPPPPLPSQ 652
Query: 256 SDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPP--PLPPP 313
S PS + I L + A ++ P +PP +PPP
Sbjct: 653 SAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPP 712
Query: 314 PPPPPPPRP----------VLPPPAPKVEITPEPVSV--VAAVVDGAVVAARGVIIAPRS 361
PPPPPPP P P P+ P P+ + V + +AP +
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ----------VAPPT 762
Query: 362 EEGAPRPPPAPLPPHDSP 379
P P PAPLPP P
Sbjct: 763 PP-PPPPIPAPLPPQAPP 779
Score = 77.4 bits (189), Expect = 2e-14
Identities = 91/331 (27%), Positives = 110/331 (33%), Gaps = 81/331 (24%)
Query: 136 PPAAPSSQPPPPSACPQRYVLSEDRRED---------RRADTSAHSKAGSSSPEPWARPS 186
PP P PPPP P + S R + S HS A P P S
Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694
Query: 187 -------CTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLP----PPPPL-- 233
P G P P PP QL P P AP LP PPPPL
Sbjct: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQL-----KPAPCAPSLPQFSAPPPPLKI 749
Query: 234 ------AQVAPSPPSPPPP------PRPPPTLSASDPSLDFLRAQQETANAIRELAGTLR 281
QVAP P PPPP P+ PP + P+ + T
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP 809
Query: 282 QGLAKLSEALSA-LLPLLPGTPVDSLPPPL----------PPP----------------- 313
AK A A +P P TP +PPP PPP
Sbjct: 810 VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQF 869
Query: 314 PPPPPPP----RPVLPPPA-------PKVEITP--EPVSVVAAVVDGAVVAARGVIIAPR 360
PPPP PP +P+ P PA P V+ P +P S+ D ++ P
Sbjct: 870 PPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP 929
Query: 361 SEEGAPRPPPAPLPPHDSPPHKRRKGFPTRK 391
+P P P P PP + P + G P +K
Sbjct: 930 PPP-SPVPAPPPPPPPTASPTPDKSGSPGKK 959
Score = 76.3 bits (186), Expect = 5e-14
Identities = 76/266 (28%), Positives = 106/266 (39%), Gaps = 26/266 (9%)
Query: 137 PAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQE-GGCP 195
P P PPP+ Q+ ++ S + S P P P+ Q P
Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887
Query: 196 RPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA--PSPPS--PPPPPRPPP 251
+SPP +P P S P P+P PPPPP + + P PPS P PPP PPP
Sbjct: 888 ANVAPQSPPAVKAKPKWQPS---SIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944
Query: 252 TLSAS-DPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPL 310
T S + D S + +T++ + Q + + + A P VDSL
Sbjct: 945 TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKF 1004
Query: 311 PPPPPPPPPPRPVLPPPA--PKV-EITPEPVSVVAAVVDGAVVAARGVII---------- 357
PP P + LPPPA PK ++ V++ + G V A V+
Sbjct: 1005 TPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEF 1064
Query: 358 -APRSEEGAPRPPP---APLPPHDSP 379
+P S+ P PPP PLPP + P
Sbjct: 1065 PSPPSDSDFPPPPPETELPLPPIEIP 1090
Score = 75.9 bits (185), Expect = 6e-14
Identities = 74/286 (25%), Positives = 91/286 (31%), Gaps = 67/286 (23%)
Query: 118 AILGPGVAAPGAGAGAEEPP-------------AAPSSQPPPPSACPQRYVLSEDRREDR 164
A L P AP + PP A P+ PPPP P
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP------------- 772
Query: 165 RADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPA 224
A K + P P + + P P PP+ QP P + P PP
Sbjct: 773 -LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA-FPASYIPPSPPT 830
Query: 225 PPLPPPPP--------LAQVAPSPPSPPP----------PPRPPPTLSASDPSLDFLRAQ 266
PP+P PPP A+ PSP SP P PP P P S P
Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP-------- 882
Query: 267 QETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPP 326
L+ A ++ + P S+P P P PPPPP V PP
Sbjct: 883 -------------LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP 929
Query: 327 PAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAP 372
P P P P A + G + S G +PPP P
Sbjct: 930 PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Score = 74.3 bits (181), Expect = 2e-13
Identities = 86/312 (27%), Positives = 104/312 (33%), Gaps = 72/312 (23%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPP-----------------PSACPQRYVLSEDRREDR 164
P + P + P P PPP PSA + + R
Sbjct: 613 PKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITR 672
Query: 165 RADTSAHSKAGSSSPEPWARPS-------CTPQEGGCPRPKERESPPPSALQPVQLPRLA 217
+ S HS A P P S P G P P PP Q
Sbjct: 673 LQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ----- 727
Query: 218 LSPPPPAPPLP----PPPPL--------AQVAPSPPSPPPPPRPPPTLSASDPSLDFLRA 265
L P P AP LP PPPPL QVA PP+PPPPP P L P +
Sbjct: 728 LKPAPCAPSLPQFSAPPPPLKIHQVQHITQVA--PPTPPPPPPIPAPLPPQAPPKPLVTI 785
Query: 266 QQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPP----PLPP----PPPPP 317
T+ + +A + Q P TP +PP P P PP PP
Sbjct: 786 PAPTST--KTVAPVVTQA--------------APPTPTPPVPPAKKQPAFPASYIPPSPP 829
Query: 318 PPPRPVLPPPAPK-----VEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAP 372
PP PV PP PK + P P+S V +VV P E +P PA
Sbjct: 830 TPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPAN 889
Query: 373 LPPHDSPPHKRR 384
+ P P K +
Sbjct: 890 VAPQSPPAVKAK 901
Score = 72.8 bits (177), Expect = 5e-13
Identities = 76/261 (29%), Positives = 89/261 (34%), Gaps = 88/261 (33%)
Query: 178 SPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPL-AQV 236
SP+P TP P P PPP PPPP PP PPPPPL +Q
Sbjct: 610 SPQP---KIVTPYTASQPSPPLPPPPPPP-------------PPPPPPPPPPPPPLPSQS 653
Query: 237 APS-----------------------------PPSPP-------------------PPPR 248
APS PP+PP PPP
Sbjct: 654 APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP 713
Query: 249 PPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPP 308
PPP P+ AQ + A A +L Q A L + + + P
Sbjct: 714 PPP----PPPTPGSAMAQLKPA----PCAPSLPQ-----FSAPPPPLKIHQVQHITQVAP 760
Query: 309 PLPPPPPPPPPPRPVLPPPAPKVEI-TPEPVSVVAAVVDGAVVAARGVIIAPRSEEGA-- 365
P PPPPPP P P P PP P V I P VA VV A + P ++ A
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFP 820
Query: 366 -------PRPPPAPLPPHDSP 379
P PP P+PP P
Sbjct: 821 ASYIPPSPPTPPVPVPPPTLP 841
Score = 55.8 bits (133), Expect = 7e-08
Identities = 61/247 (24%), Positives = 82/247 (33%), Gaps = 40/247 (16%)
Query: 89 EKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPS 148
+ L VP + P A A + + + P P + PP PS P PP
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Query: 149 ACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPW-ARPSCTPQEGGCPRPKERESPPPSA 207
P + D+ TS S G P P R S G P+ + S
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 208 LQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQ 267
+ PP P + P P +PP P + L+ S +
Sbjct: 1001 VSKF------------TPPAESGSPSKETLPPPAAPPKPGK----LNLSGVN-------- 1036
Query: 268 ETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPP-PLPPPPPPPPPPRPVLPP 326
L G L+QG +SA P+L G DS+ P PP PPP P
Sbjct: 1037 --------LPGVLQQG------CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL 1082
Query: 327 PAPKVEI 333
P P +EI
Sbjct: 1083 PLPPIEI 1089
Score = 50.4 bits (119), Expect = 3e-06
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 19/120 (15%)
Query: 299 PGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR--GVI 356
P P+ PPP PPPPPPPPPP P LP + + P+ V + + A++ G +
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGAL 683
Query: 357 IAP------RSEEGAPR-----------PPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
P +S+ P+ PPP P PP + K P ++ +P
Sbjct: 684 FKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP 743
Score = 37.7 bits (86), Expect = 0.018
Identities = 32/136 (23%), Positives = 49/136 (36%), Gaps = 31/136 (22%)
Query: 275 ELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEIT 334
+L + + + ++ ++L+P L P P P PP PPP P PPP P
Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP 645
Query: 335 PEPVSVVAAVVDGAVVAA----------------RGVIIAP------RSEEGAPR----- 367
P P+ +A G+ G + P +S+ P+
Sbjct: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705
Query: 368 ----PPPAPLPPHDSP 379
PPP P PP +P
Sbjct: 706 NGVVPPPPPPPPPPTP 721
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 86.3 bits (212), Expect = 5e-17
Identities = 78/282 (27%), Positives = 112/282 (39%), Gaps = 36/282 (12%)
Query: 122 PGVAAPGAGAGAEE--PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAH-------- 171
P +A AG E P APS++P PP+ P++ V S +A
Sbjct: 165 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224
Query: 172 -----SKAGSSSPEPWARPSCT-PQEGGCPR-PKERESPPPSALQPVQLPRLALSPPPPA 224
S++ SSS P + P+ + P G PR P P P LQ ++ P++ A
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 225 PPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGL 284
P L P PSP +PP P PP + P A T G
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP------------ATPPSQATTSLGS 332
Query: 285 AKLSEALSALLPLLPGTPVDSLPPPLPP----PPPPPPPPRPVLPPPAPKVEITPEPVSV 340
L +A + LP P +P+ + PP PP PP PP P PP +P +P+ +
Sbjct: 333 PTL-QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 391
Query: 341 VAAVVDGAVVA--ARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
+A + A + + AP S +P P+ PP +PP
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Score = 73.2 bits (178), Expect = 4e-13
Identities = 76/262 (29%), Positives = 96/262 (36%), Gaps = 44/262 (16%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEP 181
P +A P A PP+ P+S P P A P + + ++ A P
Sbjct: 359 PALALPPLQA----PPSPPASPPLSPLATP--------------SPQAPNALAVHLLQAP 400
Query: 182 WARPSCTPQEGGCPRPKERESPP--PSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPS 239
++ P P + P SPP PSA P Q P +PP PP PP P P
Sbjct: 401 FSPPPSPPVQAPFSPPA---SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-----PM 452
Query: 240 PPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLP 299
PS PPP+ PP L+A P L + + A LA Q L + P P
Sbjct: 453 SPSATPPPQAPPPLAA--PPLQLAKPPPQAPPA---LATPPLQALPSPPASFPGQAPFSP 507
Query: 300 GTPVDSLPPPLPPPPPPPPPPRPVL--PPPAPKVEITPEPVSVVAAVVDGAVVAARGVII 357
+ P PPP PP P+L PP P P D +V R +
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567
Query: 358 APRSEEGAPRPPPAPLPPHDSP 379
AP PPP PP SP
Sbjct: 568 L------APGPPP---PPSRSP 580
Score = 58.9 bits (141), Expect = 8e-09
Identities = 77/274 (28%), Positives = 98/274 (35%), Gaps = 33/274 (12%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEP 181
P +AAP + PP+ P+S P PSA P + A + P P
Sbjct: 433 PSLAAPPL----QVPPSPPASPPMSPSATPP----------PQAPPPLAAPPLQLAKPPP 478
Query: 182 WARPS-CTPQEGGCPRPKERESPPPSALQP-VQLPRLALSPPPPAPPLPPPPPLAQVAPS 239
A P+ TP P P P + P LP L+ PPP P PL QV PS
Sbjct: 479 QAPPALATPPLQALPSPPA-SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537
Query: 240 PPSPPP------PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLR-QGLAKLSEALS 292
PP+ P PP P P S S P L A R + TL LA S + +
Sbjct: 538 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597
Query: 293 ALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPP------PAPKVEITPEPVSVVAAVVD 346
+ L G DS P PPP P PAP + P + +
Sbjct: 598 STPEELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655
Query: 347 GAVVAARGVIIAPRSE-EGAPRPPPAPLPPHDSP 379
+A G+ +E + P P L P SP
Sbjct: 656 TGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 36.6 bits (83), Expect = 0.041
Identities = 85/363 (23%), Positives = 108/363 (29%), Gaps = 106/363 (29%)
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQ------------RYVLSE---------- 158
G P A A P P S PPP P R L+E
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 159 -----------------DRREDRRADTSAHSKAGSSSP---EPWARPSCTPQEG------ 192
R +R S SSP RP Q+G
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 193 -GCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA--------PSPPSP 243
R K E+P SAL R S P P P P ++ A P+P +
Sbjct: 131 ETVARGKATEAPKRSALSAG--ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188
Query: 244 PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAK-LSEALSALL------P 296
P PP P S S S A G L++ ++ LS + + L P
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248
Query: 297 LLPGTP-------------VDSL-PPPLPPP------------------PPPPPPPRPVL 324
GTP + +L PP + PP P P PP P
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308
Query: 325 PP---PAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAP----LPPHD 377
PP P TP P ++ + A + +P A PP AP LPP
Sbjct: 309 PPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367
Query: 378 SPP 380
+PP
Sbjct: 368 APP 370
Score = 33.5 bits (75), Expect = 0.35
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 9/93 (9%)
Query: 301 TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKV-----EITPEPVSVVAAVVDGAVVAARGV 355
TP P L P PP P P P + P A +V + +P++ A + GA +
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-- 73
Query: 356 IIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFP 388
APR+ PPA +PP K P
Sbjct: 74 --APRAGPTRTSRPPASGRGERAPPAKNTSPGP 104
Score = 32.7 bits (73), Expect = 0.59
Identities = 42/149 (28%), Positives = 53/149 (35%), Gaps = 10/149 (6%)
Query: 241 PSPPPPPRPPPTLSASDPSLDFLRAQQETA-NAIRELAGTLRQGLAKLSEALSALLPLLP 299
P PP PRPPP ++ + +L L A + E AG + G A + E+ P
Sbjct: 27 PRPPGSPRPPPPVTPA--ALRVLGAAGAVGRKPLAERAGGI--GGATIPESAPRAGPTRT 82
Query: 300 GTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARG-VIIA 358
P S PP P PV P P P+ + ARG A
Sbjct: 83 SRPPAS-GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141
Query: 359 PRS---EEGAPRPPPAPLPPHDSPPHKRR 384
P+ GA R P P SP RR
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSPAMARR 170
Score = 32.7 bits (73), Expect = 0.59
Identities = 34/133 (25%), Positives = 44/133 (33%), Gaps = 32/133 (24%)
Query: 118 AILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS 177
++ GP + A P +PSS P D + HS + +S
Sbjct: 558 SVSGPRLTLALAPGPPPPPSRSPSSTLSGP-------------------DLAGHSSSATS 598
Query: 178 SPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA 237
+PE P+ G SPPP A LA P P PP + A
Sbjct: 599 TPEELRGYDSGPEGGAA------ASPPPDA-------ELAACHPAAWSRGPAPPLAFRGA 645
Query: 238 PSPPSPPPPPRPP 250
P P P PP P
Sbjct: 646 PGAPLPWPPATGP 658
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 85.9 bits (211), Expect = 6e-17
Identities = 93/329 (28%), Positives = 116/329 (35%), Gaps = 73/329 (22%)
Query: 121 GPG---VAAPGAGAGAEEPP------------AAPSSQPPPPSACPQRYVLSEDRREDRR 165
GPG V +PG +G EP + P S PPP + P+ S R
Sbjct: 146 GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPP 205
Query: 166 ADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPR----LALSPP 221
+ +P P+ T GG R S P + +P P L PP
Sbjct: 206 VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265
Query: 222 PPAPPL-----------PPPPPLAQVAPSPPSP---------PPPPRP----PPTLSASD 257
PP PP+ PPPPP P P +P PPPP P PP L S
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 258 PSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPP 317
D ET L + + +LS+ P LP PLPPPP
Sbjct: 326 SGND------ETPR------------LPQRNLSLSSSTPPLPS---PGRSGPLPPPPSER 364
Query: 318 PPPRPVLPPPAPKVEITPEPV-----SVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAP 372
PPP PV PP + P P S A+ + +R + +PRS P PP P
Sbjct: 365 PPP-PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP 423
Query: 373 ---LPPHDSPPHKRRKGFPTRKRRGRWKS 398
PP P R GF W+S
Sbjct: 424 SAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Score = 69.7 bits (169), Expect = 4e-12
Identities = 64/215 (29%), Positives = 83/215 (38%), Gaps = 40/215 (18%)
Query: 176 SSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPA--PPLPPPPPL 233
S+S +P++ PS P P P R PP + PR + P + PP+P P
Sbjct: 135 STSAKPFSPPS-GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 234 AQVAP----SPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSE 289
Q +P SPP P P +P P P+ + TA G++RQ S
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSP-----GPTPPPFPGNRGTALG----GGSIRQSPLSSSS 244
Query: 290 ALSALLPLLPGTPVDSLPPPLPPPPPP----PPPPRPVLPPPAPKVEITPEPVSVVAAVV 345
S P LP TP +L PPPPPP P R +PPP P+ P P +
Sbjct: 245 PFSN-RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST------ 297
Query: 346 DGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
PR + PPP P P PP
Sbjct: 298 -------------PRPSASSQAPPPPPPPSRPGPP 319
Score = 36.6 bits (83), Expect = 0.041
Identities = 42/143 (29%), Positives = 49/143 (34%), Gaps = 33/143 (23%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACP--QRYVLSEDRREDRRADTSAH-------- 171
P + +PG +G PP PS +PPPP P + L R TS
Sbjct: 346 PPLPSPGR-SGPLPPP--PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402
Query: 172 SKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPP--------- 222
S++G SP RP P RP PPP P R P
Sbjct: 403 SRSGVDSPRSGPRPPLPPD-----RPSAGAPPPPP---PSTSIRNGFQDSPCEDEWESRF 454
Query: 223 ---PAPPLPPPPPLAQVAPSPPS 242
P LPPP P Q S PS
Sbjct: 455 YFHPISDLPPPEPYVQTTKSYPS 477
Score = 31.6 bits (70), Expect = 1.3
Identities = 10/12 (83%), Positives = 11/12 (91%)
Query: 309 PLPPPPPPPPPP 320
P+PPPP PPPPP
Sbjct: 2 PVPPPPAPPPPP 13
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 85.9 bits (211), Expect = 6e-17
Identities = 93/329 (28%), Positives = 116/329 (35%), Gaps = 73/329 (22%)
Query: 121 GPG---VAAPGAGAGAEEPP------------AAPSSQPPPPSACPQRYVLSEDRREDRR 165
GPG V +PG +G EP + P S PPP + P+ S R
Sbjct: 146 GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPP 205
Query: 166 ADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPR----LALSPP 221
+ +P P+ T GG R S P + +P P L PP
Sbjct: 206 VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265
Query: 222 PPAPPL-----------PPPPPLAQVAPSPPSP---------PPPPRP----PPTLSASD 257
PP PP+ PPPPP P P +P PPPP P PP L S
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 258 PSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPP 317
D ET L + + +LS+ P LP PLPPPP
Sbjct: 326 SGND------ETPR------------LPQRNLSLSSSTPPLPS---PGRSGPLPPPPSER 364
Query: 318 PPPRPVLPPPAPKVEITPEPV-----SVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAP 372
PPP PV PP + P P S A+ + +R + +PRS P PP P
Sbjct: 365 PPP-PVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP 423
Query: 373 ---LPPHDSPPHKRRKGFPTRKRRGRWKS 398
PP P R GF W+S
Sbjct: 424 SAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Score = 69.7 bits (169), Expect = 4e-12
Identities = 64/215 (29%), Positives = 83/215 (38%), Gaps = 40/215 (18%)
Query: 176 SSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPA--PPLPPPPPL 233
S+S +P++ PS P P P R PP + PR + P + PP+P P
Sbjct: 135 STSAKPFSPPS-GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 234 AQVAP----SPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSE 289
Q +P SPP P P +P P P+ + TA G++RQ S
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSP-----GPTPPPFPGNRGTALG----GGSIRQSPLSSSS 244
Query: 290 ALSALLPLLPGTPVDSLPPPLPPPPPP----PPPPRPVLPPPAPKVEITPEPVSVVAAVV 345
S P LP TP +L PPPPPP P R +PPP P+ P P +
Sbjct: 245 PFSN-RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST------ 297
Query: 346 DGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
PR + PPP P P PP
Sbjct: 298 -------------PRPSASSQAPPPPPPPSRPGPP 319
Score = 36.6 bits (83), Expect = 0.041
Identities = 42/143 (29%), Positives = 49/143 (34%), Gaps = 33/143 (23%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACP--QRYVLSEDRREDRRADTSAH-------- 171
P + +PG +G PP PS +PPPP P + L R TS
Sbjct: 346 PPLPSPGR-SGPLPPP--PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402
Query: 172 SKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPP--------- 222
S++G SP RP P RP PPP P R P
Sbjct: 403 SRSGVDSPRSGPRPPLPPD-----RPSAGAPPPPP---PSTSIRNGFQDSPCEDEWESRF 454
Query: 223 ---PAPPLPPPPPLAQVAPSPPS 242
P LPPP P Q S PS
Sbjct: 455 YFHPISDLPPPEPYVQTTKSYPS 477
Score = 31.6 bits (70), Expect = 1.3
Identities = 10/12 (83%), Positives = 11/12 (91%)
Query: 309 PLPPPPPPPPPP 320
P+PPPP PPPPP
Sbjct: 2 PVPPPPAPPPPP 13
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 82.0 bits (201), Expect = 9e-16
Identities = 85/305 (27%), Positives = 124/305 (40%), Gaps = 52/305 (17%)
Query: 122 PGVAAPGAGAGAEE--PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAH-------- 171
P +A AG E P APS++P PP+ P++ V S +A
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
Query: 172 -----SKAGSSSPEPWARPSCT-PQEGGCPR-PKERESPPPSALQPVQLPRL-------- 216
S++ SSS P + P+ + P G PR P P P LQ ++ P++
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 217 -ALSPPPPAPPLPPPPPLAQVAPSPPSPP--------------PPPRPPPTLSASDPSLD 261
AL P +P P P A + +PP+ P P P PP+ SA PSL
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA-PPSLQ 352
Query: 262 FLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPP----PPPPP 317
L + T + T G L +A + LP P +P+ + PP PP PP
Sbjct: 353 TLPSPPATPPS----QATTSLGSPTL-QATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 318 PPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVA--ARGVIIAPRSEEGAPRPPPAPLPP 375
PP P PP +P +P+ + +A + A + + AP S +P P+ PP
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 376 HDSPP 380
+PP
Sbjct: 468 SQAPP 472
Score = 73.2 bits (178), Expect = 4e-13
Identities = 76/262 (29%), Positives = 96/262 (36%), Gaps = 44/262 (16%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEP 181
P +A P A PP+ P+S P P A P + + ++ A P
Sbjct: 398 PALALPPLQA----PPSPPASPPLSPLATP--------------SPQAPNALAVHLLQAP 439
Query: 182 WARPSCTPQEGGCPRPKERESPP--PSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPS 239
++ P P + P SPP PSA P Q P +PP PP PP P P
Sbjct: 440 FSPPPSPPVQAPFSPPA---SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-----PM 491
Query: 240 PPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLP 299
PS PPP+ PP L+A P L + + A LA Q L + P P
Sbjct: 492 SPSATPPPQAPPPLAA--PPLQLAKPPPQAPPA---LATPPLQALPSPPASFPGQAPFSP 546
Query: 300 GTPVDSLPPPLPPPPPPPPPPRPVL--PPPAPKVEITPEPVSVVAAVVDGAVVAARGVII 357
+ P PPP PP P+L PP P P D +V R +
Sbjct: 547 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 606
Query: 358 APRSEEGAPRPPPAPLPPHDSP 379
AP PPP PP SP
Sbjct: 607 L------APGPPP---PPSRSP 619
Score = 58.9 bits (141), Expect = 8e-09
Identities = 77/274 (28%), Positives = 98/274 (35%), Gaps = 33/274 (12%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEP 181
P +AAP + PP+ P+S P PSA P + A + P P
Sbjct: 472 PSLAAPPL----QVPPSPPASPPMSPSATPP----------PQAPPPLAAPPLQLAKPPP 517
Query: 182 WARPS-CTPQEGGCPRPKERESPPPSALQP-VQLPRLALSPPPPAPPLPPPPPLAQVAPS 239
A P+ TP P P P + P LP L+ PPP P PL QV PS
Sbjct: 518 QAPPALATPPLQALPSPPA-SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576
Query: 240 PPSPPP------PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLR-QGLAKLSEALS 292
PP+ P PP P P S S P L A R + TL LA S + +
Sbjct: 577 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 636
Query: 293 ALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPP------PAPKVEITPEPVSVVAAVVD 346
+ L G DS P PPP P PAP + P + +
Sbjct: 637 STPEELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 694
Query: 347 GAVVAARGVIIAPRSE-EGAPRPPPAPLPPHDSP 379
+A G+ +E + P P L P SP
Sbjct: 695 TGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 37.0 bits (84), Expect = 0.031
Identities = 80/354 (22%), Positives = 104/354 (29%), Gaps = 97/354 (27%)
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQ------------RYVLSEDRR------- 161
G P A A P P S PPP P R L+E
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 162 EDRRADTSAHSKAGSSSPEPWARPSCT-------PQEGGCPRP----------------- 197
+ AG+SS P +RP + P + P P
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 198 ---------------KERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA----- 237
K E+P SAL R S P P P P ++ A
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAG--ARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 238 ---PSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAK-LSEALSA 293
P+P + P PP P S S S A G L++ ++ LS + +
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 294 LL------PLLPGTPVDSLPPPLPPP-------PPPPPPPR----PVLPPPAPKVEITPE 336
L P GTP P P P PP PPR P L P + TP
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 337 PVSVVAAVVDGAVVA-----------ARGVIIAPRSEEGAPRPPPAPLPPHDSP 379
P + + + + A A + +AP S P P PP P
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPP 362
Score = 35.4 bits (80), Expect = 0.092
Identities = 43/157 (27%), Positives = 54/157 (34%), Gaps = 17/157 (10%)
Query: 241 PSPPPPPRPPPTLSASDPSLDFLRAQQETA-NAIRELAGTLRQGLAKLSEALSALLPLLP 299
P PP PRPPP ++ + +L L A + E AG + G A + E+ P
Sbjct: 27 PRPPGSPRPPPPVTPA--ALRVLGAAGAVGRKPLAERAGGI--GGATIPESAPRAGPTRS 82
Query: 300 GTPVDSLPPPLPP--------PPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVA 351
P PP PP P PV P P P+ +
Sbjct: 83 AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 142
Query: 352 ARG-VIIAPRS---EEGAPRPPPAPLPPHDSPPHKRR 384
ARG AP+ GA R P P SP RR
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Score = 34.7 bits (78), Expect = 0.16
Identities = 27/98 (27%), Positives = 36/98 (36%), Gaps = 10/98 (10%)
Query: 301 TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKV-----EITPEPVSVVAAVVDGAVVAARGV 355
TP P L P PP P P P + P A +V + +P++ A + GA +
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 356 IIAPRSEEGAPRPPPAPLPP-----HDSPPHKRRKGFP 388
P G PA PP +PP K P
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113
Score = 32.7 bits (73), Expect = 0.59
Identities = 34/133 (25%), Positives = 44/133 (33%), Gaps = 32/133 (24%)
Query: 118 AILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS 177
++ GP + A P +PSS P D + HS + +S
Sbjct: 597 SVSGPRLTLALAPGPPPPPSRSPSSTLSGP-------------------DLAGHSSSATS 637
Query: 178 SPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA 237
+PE P+ G SPPP A LA P P PP + A
Sbjct: 638 TPEELRGYDSGPEGGAA------ASPPPDA-------ELAACHPAAWSRGPAPPLAFRGA 684
Query: 238 PSPPSPPPPPRPP 250
P P P PP P
Sbjct: 685 PGAPLPWPPATGP 697
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 81.6 bits (200), Expect = 1e-15
Identities = 73/232 (31%), Positives = 87/232 (37%), Gaps = 66/232 (28%)
Query: 141 SSQPPPP---SACPQRYVLSEDRREDRRADTS--AHSKAGSSSPEPW-------ARPSCT 188
SS PPPP SA SED A+ S ++ GS P + P
Sbjct: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
Query: 189 PQEGGCPRPKERESPPPSALQPVQLPRLALSPPPP-----APPLPPPPPLAQVAPSPPSP 243
P G P PK +PPP A P P + + PPPP +P PPPP P P
Sbjct: 304 PPLGSPPGPKPGFAPPP-APPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFA 362
Query: 244 PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPV 303
PPP PPP P+ D+ P LP P+
Sbjct: 363 APPPPPPP------PAADY---------------------------------PTLPPPPL 383
Query: 304 DSLPPPLPPPPPPPPPPRPVLPP-------PA--PKVEITPEPVSVVAAVVD 346
PPPPPPPPPP P PP PA P + T +P S + AV D
Sbjct: 384 SQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSD 435
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/209 (27%), Positives = 74/209 (35%), Gaps = 59/209 (28%)
Query: 103 PAAEDAFSAEEETIFAILGP---GVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSED 159
P AE ++ + + + GP V +P + PPA P PP P
Sbjct: 270 PPAEFSYPVDNQRGSGLAGPKRSSVVSP-----SHPPPAPPLGSPPGPKP---------- 314
Query: 160 RREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRP------KERESPPPSALQPVQL 213
+P P P P G P P PPPS
Sbjct: 315 ----------------GFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPH 358
Query: 214 PRLALSPPPPAPPLP-----PPPPLAQ----VAPSPPSPPPPPRPPPTLSASD------- 257
P A PPPP PP PPPPL+Q P PP PPPP PPP + +D
Sbjct: 359 PDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPP 418
Query: 258 PSLDFLRAQQE---TANAIRELAGTLRQG 283
P D + + ++A +L +RQG
Sbjct: 419 PLSDTTKPKSSLPAVSDARSDLLSAIRQG 447
Score = 28.9 bits (63), Expect = 8.6
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 3/53 (5%)
Query: 95 PHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPP 147
PH A P +A+ T+ P ++ P GA PP P PPPP
Sbjct: 357 PHPDFAAPPPPPPPPAADYPTLPP---PPLSQPTGGAPPPPPPPPPPGPPPPP 406
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 80.1 bits (196), Expect = 3e-15
Identities = 100/348 (28%), Positives = 121/348 (34%), Gaps = 107/348 (30%)
Query: 100 GAGPAAEDAFSAEEE--TIFAILG--PGVAAPGAGAG------AEEP-PAAPSSQPPPPS 148
G +A+D ++E ++ A LG P A+ G+ +G A P PAAP++ PPPPS
Sbjct: 298 GDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPS 357
Query: 149 ACPQRYVL--------SEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKER 200
SE R G P PS T GG P
Sbjct: 358 LMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNP 417
Query: 201 ESPPPSALQPVQLP------------------------------RL----ALSPPPPAP- 225
PPP +QP P RL + PPPP
Sbjct: 418 NGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM 477
Query: 226 -PLPPPPPLAQVAPSPPSPPPP-------PRPPPTLSASDPSLDFLRAQQETANAIRELA 277
P PPPPP Q P P P PP P PPP S+S S L QQ T A
Sbjct: 478 MPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTS-A 536
Query: 278 GTLRQGLAKLSEALSALLPLLP---GTPV-----DSLPPPLPPPPPPPPPPRPVLPPPAP 329
GT + +A +A P P G P + PPLPP PPPPPP PPP
Sbjct: 537 GTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP----PPPG- 591
Query: 330 KVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHD 377
+ G++ AP PP P PP D
Sbjct: 592 ----------------------SAGMMYAP---------PPPPPPPMD 608
Score = 67.4 bits (163), Expect = 2e-11
Identities = 64/247 (25%), Positives = 85/247 (34%), Gaps = 64/247 (25%)
Query: 95 PHSTQGAGPAAEDAFSAEEETIFAIL----GPGVAAPGAGAGAEEPPAAPSSQPPPPSAC 150
PH GP D + + G G+ P PP PS QPPPP +
Sbjct: 436 PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSG 495
Query: 151 PQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQE----GGCPRPKERESPP-- 204
P + ++ S S SS+P PW + + T G P +++++
Sbjct: 496 PLPPWQQQQQQPPPPPPPS--SSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553
Query: 205 -PSALQPVQLPRLALSPP-------PPAPPLPPPPP--LAQVAPSPPSPPPPPRPPPTLS 254
P A Q P + PP P APP PPPPP A + +PP PPPPP P
Sbjct: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFV 613
Query: 255 ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPP 314
+ G V +PP PP
Sbjct: 614 T------------------------------------------MMGMGVAGMPPFGMPPA 631
Query: 315 PPPPPPR 321
PPPPPP+
Sbjct: 632 PPPPPPQ 638
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 79.3 bits (194), Expect = 6e-15
Identities = 86/290 (29%), Positives = 117/290 (40%), Gaps = 54/290 (18%)
Query: 118 AILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS 177
A + P A+P + + P P PP A P+ R+ ++ G
Sbjct: 581 AKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPR----------PSRSSPGLYTSPGQD 630
Query: 178 SPEPWARPSCTPQEGG---------CPRPKERESPPPS-----ALQPVQLPRLALSPPPP 223
S +P A +P GG P+ +++P PS A Q R +L PP
Sbjct: 631 SLQPTA---VSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPP 687
Query: 224 APPLPPPPPLAQ---VAPSP---------PSPPP-PPRPPPTLSASDPSLDFLRAQQETA 270
P PP + V+P P SPPP PP PP + S S+ S+ LR + E
Sbjct: 688 WTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEAR 747
Query: 271 NAIRELAGTLRQGLAKLSEALSALLPLLPGT--PVDSLPPPLPPPPPPPPPPRPVLPPPA 328
R+L L + + + SA P G P PP PPPPPPPPPP P +
Sbjct: 748 PPSRQLQALLARNIINAARRKSAS-PRSAGAENPRPFSPPRAPPPPPPPPPPPPRMR--- 803
Query: 329 PKVEITPEPVSVVAAVVDGAVVA--ARGVIIAPRSEEGAPRPP-PAPLPP 375
+P+P +A V GA A R + A S +PR P PAP P
Sbjct: 804 -----SPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848
Score = 61.2 bits (147), Expect = 2e-09
Identities = 86/304 (28%), Positives = 111/304 (36%), Gaps = 49/304 (16%)
Query: 122 PGVAAPGAGAGAEEPPAA---------------PSSQPPPPSACPQRYVLSEDRREDRRA 166
PG + + A PPA+ P+ QPP P +VLS + E +
Sbjct: 526 PGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLR-PSLFVLSPIK-EPAKV 583
Query: 167 DTSAHSKAGSSSPE--PWARPSCTPQEGGCPRPKERE-----SPPPSALQPVQLPRLALS 219
A S A SS + P P PRP SP +LQP A+S
Sbjct: 584 SPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT-----AVS 638
Query: 220 PPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGT 279
PP P P A SP P P+ S + ++ AQ + T
Sbjct: 639 PPYGGDISPVSPSRAW------SPRAKQAPRPSFSTRNAGIE---AQDRRESLPTSPPWT 689
Query: 280 LRQGLAKLSEALSALL---PLLPGTPVD-SLPPPLPPPPPPPPP-PRPVLPPPAPKVEIT 334
G ++ +L + P PG S PPPLPPPPP P + P P+ E
Sbjct: 690 --PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEAR 747
Query: 335 PEPVSVVAAVVDGAVVAARGVIIAPRSEEGA-PRP---PPAPLPPHDSPPHKRRKGFPTR 390
P + A + + AAR +PRS PRP P AP PP PP R P
Sbjct: 748 PPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQP 807
Query: 391 KRRG 394
R G
Sbjct: 808 ARPG 811
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/229 (26%), Positives = 76/229 (33%), Gaps = 67/229 (29%)
Query: 68 SWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAG--PAAEDAFSAEEETIFAILGPGVA 125
S + G E Q R +E L P T GA P++ D + + PG
Sbjct: 667 STRNAGIEAQDR--------RESLPTSPPWTPGASRPPSSLDGW----------VSPGPW 708
Query: 126 APGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARP 185
PG G+ PP P P PS + E R + + R
Sbjct: 709 EPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRK 768
Query: 186 SCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPP-------------- 231
S +P+ G P+ P PR +PPPP PP PPPP
Sbjct: 769 SASPRSAGAENPR-----------PFSPPR---APPPPPPPPPPPPRMRSPQPARPGSAA 814
Query: 232 -PLAQVAPSPPSPPP-------------PPRPPPTL-----SASDPSLD 261
P A AP P SP P P P P L + SD SLD
Sbjct: 815 VPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLD 863
Score = 29.3 bits (64), Expect = 6.6
Identities = 27/115 (23%), Positives = 44/115 (38%), Gaps = 12/115 (10%)
Query: 111 AEEETIFAILGPGVAAPGA------GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDR 164
AE + A + +A+P A + PPA +Q PP + PQ LS ++
Sbjct: 60 AEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQ--- 116
Query: 165 RADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALS 219
S+ ++ S+ P ++PS +G P E + V P S
Sbjct: 117 ---NSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS 168
Score = 28.9 bits (63), Expect = 8.6
Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 5/89 (5%)
Query: 128 GAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSC 187
G A A +PP+ P P P R + E R +R+ S G+ + A P+
Sbjct: 266 GEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFT----APPTY 321
Query: 188 TPQEGGCPRPKERESPPP-SALQPVQLPR 215
T P SPP S L P P+
Sbjct: 322 TETLSTAPLASWVRSPPSYSVLYPSSDPK 350
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 78.6 bits (192), Expect = 9e-15
Identities = 77/264 (29%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 134 EEPPAAPSSQP--PPPSACPQRYVLSEDRRED--RRADTSAHSKAGSSSPEPWARPSCTP 189
E PP+ P PPP A P E TS +A SP P P P
Sbjct: 525 ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584
Query: 190 QEGGCPRPKERESPPPSALQPVQ-LPRLALSPPPPAPPLPPPPPLAQVAP----SPPSPP 244
E + SPPP A + LSPPP PL PPP ++++P SP SPP
Sbjct: 585 PE------ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
Query: 245 P---PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGT 301
P P PPP +S P + L+ + S P P
Sbjct: 639 PEESPMSPPPEVSRLSP-----------LPVVSRLSPPPEESPLSPPPEESPTSP--PPE 685
Query: 302 PVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR--GVIIAP 359
PPP P PPP P PPP + P S + + + + R G ++P
Sbjct: 686 ASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745
Query: 360 RSEEG--APRPPPAPLPPHDSPPH 381
R EE +PRP L P PH
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPH 769
Score = 66.6 bits (161), Expect = 4e-11
Identities = 75/277 (27%), Positives = 96/277 (34%), Gaps = 47/277 (16%)
Query: 126 APGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDR--REDRRADTSAHSKAGSSSPEPWA 183
+P A PP S PPP P R + S + SP P A
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623
Query: 184 RPSCTPQEGGCPRPKERE---SPPPSALQPVQLPRLA-LSPPPPAPPLPPPPPLAQVAPS 239
P E P E SPPP + LP ++ LSPPP PL PPP + +P
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP 683
Query: 240 PP----SPPP---PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALS 292
P SPPP P PPP S + P + L L S
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPE--------------------DSLMSLPLEES 723
Query: 293 ALLP------LLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVD 346
LLP L P + L P P P P P L P A + ++P+P V
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV- 782
Query: 347 GAVVAARGVIIAPRSE--EGAPRPPPAPLPPHDSPPH 381
++P++E +P+P L P PH
Sbjct: 783 -----PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814
Score = 66.2 bits (160), Expect = 5e-11
Identities = 74/252 (29%), Positives = 90/252 (35%), Gaps = 54/252 (21%)
Query: 178 SPEPWARPSCTPQEGGCPRPKERE---SPPPSALQPVQ-LPRLALSPPPPAPPLPPPP-- 231
SP P P+ P E P E SP P AL + L LSPPP PL PPP
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509
Query: 232 ---------PLAQVAPSPPSP--PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTL 280
PL+ SPPSP P PPP S P + + + EL +
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE----ESPLSPPPEELPTSP 565
Query: 281 RQGLAKLS--------------------EALSALLPLLPGTPVDSLP--PPLPPPP---- 314
++LS S L P +P+ P PL PPP
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
Query: 315 -PPPPPPRPVLPPPAPKVEITPEPVSVVA--AVVDGAVVAARGVIIAPRSEEGAPRPPPA 371
PPP P+ PPP P VS ++ VV ++P EE PPP
Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE 685
Query: 372 PL----PPHDSP 379
PP DSP
Sbjct: 686 ASRLSPPPEDSP 697
Score = 64.3 bits (155), Expect = 2e-10
Identities = 78/285 (27%), Positives = 107/285 (37%), Gaps = 57/285 (20%)
Query: 120 LGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTS---------- 169
L P P EE +P ++ P S P+ LS E + S
Sbjct: 788 LSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPE 847
Query: 170 -AHSKAGSSSPEPWARPSCTPQEGG-CPRPKERES-PPPS--ALQPVQLPRLALSPP--P 222
+H P RP P+E G CP P+E PPP +L P+ L ALS P P
Sbjct: 848 ESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPL-LGEPALSEPGEP 906
Query: 223 PAPPLPPPPPLA-----QVAPS--PPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRE 275
P PLP PL+ ++P PP P PPP P +A+ P+L
Sbjct: 907 PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALS-------------- 952
Query: 276 LAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITP 335
L +L A P +P+ + P L P PPP P P P + + P
Sbjct: 953 -------PLGELEYPFGAKGDSDPESPLAA--PILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 336 EPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
P S V A +++ P + +P + L P +SPP
Sbjct: 1004 SPGSPVG--------PASPILMEPLPPQCSPLLQHS-LVPQNSPP 1039
Score = 63.5 bits (153), Expect = 3e-10
Identities = 65/205 (31%), Positives = 82/205 (40%), Gaps = 32/205 (15%)
Query: 195 PRPKERESPPPSALQPVQLPRLA--LSPPP---PAPPLPPPPPLAQ-VAPSPPSPPP--- 245
P P+E PP P P A LSPPP PA PLP L++ + SP SPPP
Sbjct: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEES 501
Query: 246 PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDS 305
P PPP S P + + E + + L L+ EA S L P +P+
Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPP----SPALETPLSPPPEA-SPLSPPFEESPLSP 556
Query: 306 LPPPLPPPPP-------PPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIA 358
P LP PP PPP P+ PPP P S + + + ++
Sbjct: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-------LS 609
Query: 359 PRSEEGAPRPPPAPL----PPHDSP 379
P EE PPP PP DSP
Sbjct: 610 PPPEESPLSPPPEASRLSPPPEDSP 634
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/288 (28%), Positives = 104/288 (36%), Gaps = 58/288 (20%)
Query: 120 LGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSP 179
L P P AEEP +P + P A P+ LS + +
Sbjct: 752 LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811
Query: 180 EPWARPSCTPQEGGCPRPKERESP-PPSALQPVQLPRLA---LSPPPPAPPLPPPPPLAQ 235
EP P P+E C P+ ES P + +P PR LSP PPL P P +
Sbjct: 812 EPHLSP--VPEEP-CLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP---E 865
Query: 236 VAPSPPSPPPPPR-----PPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEA 290
P P P P PPP +PSL L + + G LS
Sbjct: 866 KPPEEPGQCPAPEELPLFPPP----GEPSLSPLLGEPALSEP----------GEPPLSP- 910
Query: 291 LSALLPLLP-GTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITP-------------- 335
L LPL P G P SL P L PP P PPP P++ AP ++P
Sbjct: 911 LPEELPLSPSGEP--SLSPQLMPPDPLPPPLSPIITAAAPPA-LSPLGELEYPFGAKGDS 967
Query: 336 EPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAP---LPPHDSPP 380
+P S +AA + I+P E P P P LPP P
Sbjct: 968 DPESPLAAPI-------LETPISPPPEANCTDPEPVPPMILPPSPGSP 1008
Score = 55.1 bits (131), Expect = 1e-07
Identities = 68/251 (27%), Positives = 88/251 (35%), Gaps = 82/251 (32%)
Query: 126 APGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARP 185
+PG G +EPP A + P PPS P + + GS + +P+A+P
Sbjct: 2342 SPGLGLRPQEPPPAQALAPSPPSH-PDIF------------------RPGSYT-DPYAQP 2381
Query: 186 SCTPQEGGCPRPKERESPPPS---ALQPVQLPRLALSPPPPAP--------PLPPPPPLA 234
TP+ P+P PPP AL P LP S P +P PL P P A
Sbjct: 2382 PLTPR----PQP-----PPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSA 2432
Query: 235 QV-APSP-----PSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLS 288
+ PSP SP P RPP + DP + + + AG+L A S
Sbjct: 2433 EAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSL----AHTS 2488
Query: 289 EALSALLPLLPGTPVDSLPPPLPPPPPP-------------------------------- 316
LP P L +P PP
Sbjct: 2489 LGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLK 2548
Query: 317 PPPPRPVLPPP 327
PP P+P LPPP
Sbjct: 2549 PPVPQPGLPPP 2559
Score = 53.1 bits (126), Expect = 4e-07
Identities = 69/243 (28%), Positives = 92/243 (37%), Gaps = 45/243 (18%)
Query: 177 SSPEPWARPSCTPQ----------EGGCPRPKERESPPPSALQ--PVQLPRLALSPPPPA 224
S PEP P+ P +GG + + P P + P+ + L P A
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432
Query: 225 P-----PLPPPPPLAQVAPSPPSPPP---PPRPPPTLSASDPSLDFLRAQ--QETANAIR 274
P PL PPP SP SPPP P PPP S P + L A E + R
Sbjct: 433 PLNEEMPLLPPPE-----ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR 487
Query: 275 ELAGTLRQGLAKLSEALSALLPLLPGTPVDSLP--PPLPPPPPP-------PPPPRPVLP 325
L + + S LS P +P++ P PP PP P PPP L
Sbjct: 488 PLEESPLSPPPEES-PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS 546
Query: 326 PPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRK 385
PP + ++P P + + A ++P EE PPP P SPP + +
Sbjct: 547 PPFEESPLSPPPEELPTSPPPEA------SRLSPPPEESPMSPPPEESPM--SPPPEASR 598
Query: 386 GFP 388
FP
Sbjct: 599 LFP 601
Score = 47.8 bits (112), Expect = 2e-05
Identities = 70/286 (24%), Positives = 99/286 (34%), Gaps = 55/286 (19%)
Query: 135 EPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEG-G 193
EP +P PP P P +++ A A S G A+ P+
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITA-------AAPPALSPLGELEYPFGAKGDSDPESPLA 974
Query: 194 CPRPKERESPPPSA--LQPVQLPRLALSPPPPAP----------PLPPP-PPLAQVAPSP 240
P + SPPP A P +P + L P P +P PLPP PL Q + P
Sbjct: 975 APILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVP 1034
Query: 241 PSPPPPPRPPPTLSASDPS-------------------LDFLRAQQETANAIRELAGT-L 280
+ PP PP L S PS ++ + + A+ A + L
Sbjct: 1035 QNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPL 1094
Query: 281 RQGLAKLSEALSALLPLLPG--------TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVE 332
+ LS + P L P+D + P P P P V
Sbjct: 1095 PSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVL 1154
Query: 333 ITPE---PVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPP 375
+ PE PV+ + + A +G +P E+ PR P AP PP
Sbjct: 1155 LDPEELAPVTPMEVYPECKQTAGQG---SPCEEQEEPRAPVAPTPP 1197
Score = 47.0 bits (110), Expect = 3e-05
Identities = 78/327 (23%), Positives = 109/327 (33%), Gaps = 50/327 (15%)
Query: 90 KLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSA 149
+L+ P + + P E S E + L P EE P +P + P S
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPPEV--SRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682
Query: 150 CPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPP-PSAL 208
P+ LS + +SP P P+ P E ESP P
Sbjct: 683 PPEASRLSPPPEDS------------PTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 209 QPVQLPRLA---LSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRA 265
+P PR LSP P P L P P ++P P P+P + P L
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790
Query: 266 QQETANAIRE--------------LAGTLRQGLAKLSEALSALLP------LLPGTPVDS 305
Q E + + L+ + S L P L P
Sbjct: 791 QAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850
Query: 306 LPPPLPPPPPPPPPPRPVLPP---PAP-KVEITPEP--VSVVAAVVDGAVVAARGVIIAP 359
L P L PP P P +P P PAP ++ + P P S+ + + A+ ++P
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP 910
Query: 360 RSEE------GAPRPPPAPLPPHDSPP 380
EE G P P +PP PP
Sbjct: 911 LPEELPLSPSGEPSLSPQLMPPDPLPP 937
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/92 (34%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 305 SLPPPLPPPPPPPP-PPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEE 363
S PPP P PPP P P P PP P VE+ EP++ + V + + +P S
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA------EPPVPSPLPLASSPESAR 4960
Query: 364 GAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGR 395
PR P P DS P + +K R +R R
Sbjct: 4961 PKPRARP-PEEGEDSRPPRLKKWKGVRWKRLR 4991
Score = 44.3 bits (103), Expect = 2e-04
Identities = 67/258 (25%), Positives = 80/258 (31%), Gaps = 56/258 (21%)
Query: 127 PGAGAGAE---EPPAAPSSQPPPPSA-----CPQRYVLSEDRR----------------- 161
PGAG E PP P QP P CP L+
Sbjct: 2218 PGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Query: 162 --EDRRADTSAHSKAGSSSPEPWA-------RPSCTPQEGGCPRP-----KERESPPPSA 207
E R+A + G+SSP PS GG K +P S
Sbjct: 2278 FGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQ 2337
Query: 208 LQPVQLPRLALSP--PPPAPPLPPPPP----------LAQVAPSPPSPPPPPRPPPTLSA 255
++P Q P L L P PPPA L P PP PP P P PPP
Sbjct: 2338 VEP-QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCC 2396
Query: 256 SDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPP 315
+ P A + + + L + A P P TP P P PP
Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS-PVTPRFQSPDPYSRPPS 2455
Query: 316 PPPPPRPVLP---PPAPK 330
P P P PP P+
Sbjct: 2456 RPQSRDPFAPLHKPPRPQ 2473
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/83 (36%), Positives = 32/83 (38%), Gaps = 13/83 (15%)
Query: 186 SCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPP- 244
S QE P P + S L LS PPP P PPP PLA SPP+ P
Sbjct: 4877 SLLKQESPAPEPPTQHS---YTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPL 4933
Query: 245 ---------PPPRPPPTLSASDP 258
PP P P AS P
Sbjct: 4934 VELPTEPLAEPPVPSPLPLASSP 4956
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 21/102 (20%)
Query: 173 KAGSSSPEPWARPSCTPQEGGCP------RPKERESPPPSALQP----------VQLPRL 216
K S +PEP + S T P E SPPPS L P V+LP
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP-- 4937
Query: 217 ALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDP 258
+ P PP+P P PLA +P P P RPP S P
Sbjct: 4938 --TEPLAEPPVPSPLPLAS-SPESARPKPRARPPEEGEDSRP 4976
Score = 40.8 bits (94), Expect = 0.002
Identities = 75/321 (23%), Positives = 99/321 (30%), Gaps = 112/321 (34%)
Query: 137 PAAPSSQPPPPS---ACPQRYVLSEDRREDRRADTSAHS------KAGSSSPEPWARPSC 187
P AP + PP PS A Q +L R H+ + S+P+P+ +P C
Sbjct: 2190 PTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC 2249
Query: 188 ----------TPQEGGCPRPKERESPPP-----SALQPVQLPRLALSPPPPAPP------ 226
+P GG + SPPP AL+ V+ L S P PP
Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE-VKKEELGASSPSYGPPNLGFVD 2308
Query: 227 --------------------LPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSL----DF 262
P P +QV P P P+ PP A PS D
Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI 2368
Query: 263 LRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRP 322
R PG+ D P P P PPPP
Sbjct: 2369 FR----------------------------------PGSYTDPYAQPPLTPRPQPPPPES 2394
Query: 323 --VLPP------PAPKVEITPEPVSVVAAVVDGAVVAARGVI---IAPRSEEGAP--RPP 369
LPP P +V +P+ S + + ++A + PR + P RPP
Sbjct: 2395 CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454
Query: 370 PAP----------LPPHDSPP 380
P PP PP
Sbjct: 2455 SRPQSRDPFAPLHKPPRPQPP 2475
Score = 39.7 bits (91), Expect = 0.005
Identities = 57/231 (24%), Positives = 75/231 (32%), Gaps = 45/231 (19%)
Query: 168 TSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPL 227
T + + G+ + C PQ GG P P Q L L P P PP
Sbjct: 4240 TPPYQEPGTQTSPLQGLLGCQPQLGGFPGP-----------QTGPLQELGAGPRPQGPPR 4288
Query: 228 PPPPP--------LAQVAPSPP--SPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELA 277
P PP L V P+PP SP P RP S S + +
Sbjct: 4289 LPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
Query: 278 GTLRQGLAKLSEALSALLPLL------PGTPVDSLPPPLPPPPPPPPP-----PRPVLPP 326
TL ++S A + L L P P D+L P P + P
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVP 4408
Query: 327 PAPKVEITPEP--------VSVVAAVVDGAVVAARG-----VIIAPRSEEG 364
A ++ I EP V +G + A G ++ PRSE G
Sbjct: 4409 EASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAG 4459
Score = 30.4 bits (67), Expect = 2.9
Identities = 37/121 (30%), Positives = 45/121 (37%), Gaps = 18/121 (14%)
Query: 214 PRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAI 273
P L L PP L PPP A +P P P LS S FL+ +
Sbjct: 2100 PALHLRIPPQPGALGSPPP----AAAPTIFIGSPTTPAGLSTSADG--FLKPPAGSVPG- 2152
Query: 274 RELAGTLRQGLAKLSEALSALLP------LLPGTPVDSLPPPLPP--PPPPPPPPRPVLP 325
+ G L KL + A +P L P P++ P PP PP P P P P
Sbjct: 2153 PDSPGEL---FLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQP 2209
Query: 326 P 326
P
Sbjct: 2210 P 2210
Score = 30.0 bits (66), Expect = 3.8
Identities = 27/88 (30%), Positives = 34/88 (38%), Gaps = 13/88 (14%)
Query: 185 PSCTPQEGGCPRPKERESP---PPSALQPVQLPRLALSPPPPAPPLPPPPPLA--QVAPS 239
P TP G P + R P P L P L LA+S PP P PP P + P+
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT 2949
Query: 240 PPSPPPP--------PRPPPTLSASDPS 259
P + P RPP + P+
Sbjct: 2950 PHTKGPTLPTGLELVNRPPSSTELGRPN 2977
Score = 30.0 bits (66), Expect = 3.8
Identities = 65/292 (22%), Positives = 96/292 (32%), Gaps = 56/292 (19%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDR-----RADTSAHSKAGS 176
PG P ++ P QP P S Q + +++ + A +H + GS
Sbjct: 4062 PGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGS 4121
Query: 177 SSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPP---LPPPPPL 233
S E S P QP ++L P + L P P+
Sbjct: 4122 GSSS------------------EASSVPHLLAQP----SVSLGDQPGSMTQNLLGPQQPM 4159
Query: 234 AQVAPSPPSPPPPPRPPPTLSASD--------PSLDFLRAQQETANA----IRELAGTLR 281
+ + P PP+P P L + P++ LRAQ + A +R L+ +
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219
Query: 282 QGLAKL--------SEALSALLPLL-PGTPVDSLPPPLPPPPPPPPPPRPVLPP-----P 327
Q L L S+A+ P PGT L L P P P P
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279
Query: 328 APKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSP 379
P+ + P + A+ G V+ P S + RP P P P
Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331
Score = 29.6 bits (65), Expect = 5.0
Identities = 51/204 (25%), Positives = 64/204 (31%), Gaps = 50/204 (24%)
Query: 136 PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCP 195
PP + PPP+A P ++ S + AG S+ A P G P
Sbjct: 2107 PPQPGALGSPPPAAAPTIFI------------GSPTTPAGLSTS---ADGFLKPPAGSVP 2151
Query: 196 RPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSA 255
P +SP L L PP P P +AP+ P P P PPT
Sbjct: 2152 GP---DSPG----------ELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPP 2198
Query: 256 SDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPP 315
PS AQ L + R G G P + P P
Sbjct: 2199 Y-PSPTGAPAQPPM------LGASSRPG---------------AGQPGEFHTTPPGTPRH 2236
Query: 316 PPPPPRPVLPPPAPKVEITPEPVS 339
P P P L P P ++ P S
Sbjct: 2237 QPSTPDPFLKPRCPSLDNLAVPES 2260
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 78.6 bits (192), Expect = 9e-15
Identities = 88/281 (31%), Positives = 107/281 (38%), Gaps = 53/281 (18%)
Query: 127 PGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPW--AR 184
PG+ A + P S P P A P+ SE AH A ++ P P A
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSE-----------AHGAARTAPPRPNVPAP 174
Query: 185 PSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPP--LPPPPPLAQVAPSPPS 242
P TP P P PP + P++ P +SPP P LP P AP PP
Sbjct: 175 PPPTP-----PPPPPPLPPPLPSSSPIKTP--LVSPPGPLTKGNLPVVAPPVPCAPPPPP 227
Query: 243 PPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTP 302
PPPPP PPP AS S ++ Q + + L L L P +P
Sbjct: 228 PPPPPTPPPLPPASVLSDKAVKPQLAPLH-----LPPIPPPLPLLPPCGYPGLKAEPASP 282
Query: 303 V-DSLPPPLPPPPPPP---PPPRPVLP-PPAPKVEI---TPEPVSVVAAVVDGAVVAARG 354
D+ PP PPPP PP PR LP PP P V TP P+ +
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ-------- 334
Query: 355 VIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGR 395
AP + GA P P PP P F +KR GR
Sbjct: 335 ---APPQKAGAQALPAPPAPPGSQP-------FLQKKRHGR 365
Score = 76.3 bits (186), Expect = 5e-14
Identities = 85/314 (27%), Positives = 112/314 (35%), Gaps = 98/314 (31%)
Query: 136 PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKA-----------------GSSS 178
PP + PPPPSA P +S D RRAD S S+
Sbjct: 15 PPPLGAPPPPPPSAPP----VSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70
Query: 179 PEPWARPSCTPQEGGCPRPKERESPP-----------------------------PSALQ 209
P+ + + GG + +PP P +
Sbjct: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRA 130
Query: 210 P-VQLPRLALSPP--PPAPP--------------LPPPPPLAQVAPSPPSPPPPPRP-PP 251
P +LP +S P PPA P PP P + AP PP+PPPPP P PP
Sbjct: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP--APPPPTPPPPPPPLPP 188
Query: 252 TLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLP 311
L +S P + G L +G LP++ PV PPP P
Sbjct: 189 PLPSSSP----------IKTPLVSPPGPLTKG----------NLPVV-APPVPCAPPPPP 227
Query: 312 PPPPPPPPPRP---VLPPPAPKVEITP---EPVSVVAAVVDG-AVVAARGVIIAPRSEEG 364
PPPPP PPP P VL A K ++ P P+ ++ + +P +
Sbjct: 228 PPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQ 287
Query: 365 APRPPPAPLPPHDS 378
P PP PLPP+ S
Sbjct: 288 EPPAPPPPLPPYAS 301
Score = 63.2 bits (152), Expect = 4e-10
Identities = 64/241 (26%), Positives = 80/241 (33%), Gaps = 82/241 (34%)
Query: 216 LALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDP---SLDFLRAQQET--- 269
+ + PPPP P PPPPPL P PPS PP +L +DP S QQ T
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
Query: 270 ---------ANAIRELAGTLRQGLAK-----------LSEALSALLPLL----------- 298
A I GT ++G L + + P+L
Sbjct: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
Query: 299 ------------PGTPVDSLPPPLPPP--------------------------PPP--PP 318
P P ++ PL PP PPP PP
Sbjct: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180
Query: 319 PPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDS 378
PP P LPPP P + P+ G + ++AP AP PPP P PP
Sbjct: 181 PPPPPLPPPLP----SSSPIKTPLVSPPGPLTKGNLPVVAP-PVPCAPPPPPPPPPPTPP 235
Query: 379 P 379
P
Sbjct: 236 P 236
Score = 47.4 bits (111), Expect = 2e-05
Identities = 70/257 (27%), Positives = 88/257 (34%), Gaps = 64/257 (24%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEP 181
P VA P A PP P + PP P A VLS+ + + A P P
Sbjct: 213 PVVAPPVPCAPPPPPPPPPPTPPPLPPAS----VLSDKAVKPQLAPLHL---PPIPPPLP 265
Query: 182 WARPSCTP---QEGGCPRPKERESP-PPSALQPVQ--LPRLALSPPP---------PAPP 226
P P E P +E P PP L P PR +L PP PP
Sbjct: 266 LLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPP 325
Query: 227 LPPPPPL---------AQVAPSPPSPP----------------------PPPRPPPTLSA 255
LPP P AQ P+PP+PP PPP PP
Sbjct: 326 LPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPT 385
Query: 256 SDPSLDFLRAQQETA-NAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPP 314
++ S ++QQ TA ++ G LR G + + + V+ PPP P
Sbjct: 386 TELS---SKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTF---HSVEDFPPPDEYKP 439
Query: 315 ----PPPPPPRPVLPPP 327
P PR P P
Sbjct: 440 CQKIYPSKIPRSRTPGP 456
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 77.8 bits (190), Expect = 2e-14
Identities = 90/325 (27%), Positives = 119/325 (36%), Gaps = 92/325 (28%)
Query: 100 GAGPAAEDAFSAEEE--TIFAILG--PGVAAPGAGAG------AEEP-PAAPSSQPPPPS 148
G +A+D ++E ++ A LG P A+ G+ +G A P PAAP++ PPPPS
Sbjct: 298 GDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPS 357
Query: 149 ACPQRYVL--------SEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKER 200
SE R G P PS T GG P
Sbjct: 358 LMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNP 417
Query: 201 ESPPPSALQP------------------------------------------VQLPRLAL 218
PPP +QP + P + +
Sbjct: 418 NGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM 477
Query: 219 SPPPPAP--PLPPPPPLAQVAP---SPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAI 273
PPPP P PPPPP + P PPPPP P ++++S P L QQ T
Sbjct: 478 MPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP----LPWQQNTTTTT 533
Query: 274 RELAGT-------LRQGLAKLS------EALSALLPLLPGTPVDSLPPPLPPPPPPPPPP 320
AGT +Q A S + ++PL PG LPP PPPPPPPPP
Sbjct: 534 TS-AGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQ-PPLPPGAPPPPPPPPPG 591
Query: 321 RP--VLPP-----PAPKVEITPEPV 338
++PP P+ + E P P+
Sbjct: 592 SAGMMIPPRGGDGPSHESEDFPRPL 616
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 77.4 bits (189), Expect = 2e-14
Identities = 79/280 (28%), Positives = 104/280 (37%), Gaps = 40/280 (14%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDR-------RADTSA---- 170
P + P + A A PP + +S P R L E R R R +T++
Sbjct: 111 PALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGM 170
Query: 171 -HSKAGSSSPEPWAR----PSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAP 225
HS + P P R P+ P RE P P P Q PP P
Sbjct: 171 KHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPT--PGQRLHPGREGPPAPP 228
Query: 226 PLPPPPPLAQVAPSPP----SPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLR 281
P+ PPP + P +PPPPP P + PS E+A + + +L
Sbjct: 229 PVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPS----SPTNESAPELPQRHNSLH 284
Query: 282 QGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKV------EITP 335
+ K + L P P + SL PPPP PP R PPP P V + P
Sbjct: 285 R---KTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPP 341
Query: 336 EPVSVVAAVVDGAVVAARGVIIAP--RSEEGAPRPPPAPL 373
P + G+ +RG P R+ G P PPP PL
Sbjct: 342 PPPPY---RMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPL 378
Score = 53.1 bits (126), Expect = 4e-07
Identities = 49/174 (28%), Positives = 60/174 (34%), Gaps = 34/174 (19%)
Query: 132 GAEEPPAAPSSQPPPPSAC----PQRYVLSEDR---REDRRADTSAHSKAGSSSPE---- 180
G E PPA P +PPP P L+ R+ S S+PE
Sbjct: 220 GREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQR 279
Query: 181 --PWARPSCTPQEGGCPRPKERESP-------PPSALQPVQLPRLALSPPPPAPPL---- 227
R + P G P P SP PP A P P +PPPP P +
Sbjct: 280 HNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDP---PSRGAAPPPPPPVIRNGA 336
Query: 228 ----PPPPPLAQVAPSPPS---PPPPPRPPPTLSASDPSLDFLRAQQETANAIR 274
PPPPP PPS PPPPP P P +++ +R
Sbjct: 337 RDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVR 390
Score = 50.4 bits (119), Expect = 3e-06
Identities = 55/183 (30%), Positives = 68/183 (37%), Gaps = 45/183 (24%)
Query: 120 LGPGVAAPGAGAGAEEPPA------APSSQ----PPPPSACPQRYV------LSEDRRED 163
L PG P A + PP+ PS Q PPPP P +E E
Sbjct: 217 LHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPEL 276
Query: 164 RRADTSAHSKA-----GSSSPEPW-ARPSCTPQEGGCPRPKERESPPPSALQPVQLPRL- 216
+ S H K G + P P A PS P P R+ P A P P +
Sbjct: 277 PQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNR---PPPPARDPPSRGAAPPPPPPVIR 333
Query: 217 --ALSPPPPAPPL------------PPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDF 262
A PPP PP PPPPP + +P PPPPP PPP + S+
Sbjct: 334 NGARDAPPPPPPYRMHGSEPPSRGKPPPPP----SRTPAGPPPPP-PPPLRNGHRDSITT 388
Query: 263 LRA 265
+R+
Sbjct: 389 VRS 391
Score = 35.8 bits (81), Expect = 0.070
Identities = 12/15 (80%), Positives = 13/15 (86%)
Query: 306 LPPPLPPPPPPPPPP 320
+PPP PPPP PPPPP
Sbjct: 3 IPPPPPPPPGPPPPP 17
Score = 33.9 bits (76), Expect = 0.27
Identities = 48/210 (22%), Positives = 69/210 (32%), Gaps = 37/210 (17%)
Query: 216 LALSPPPPAPPLPPPPPLAQVA--PSPPSPPPPPRPPPTL--------------SASDPS 259
+ + PPPP PP PPPPP A P R L + +D S
Sbjct: 1 MPIPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRS 60
Query: 260 LDFLRAQQETAN-------AIRELAGTLRQGLAKL----SEALSALLPLLPGTPVDSLPP 308
L + ++ A++ G + G+ KL ++ S L P + S
Sbjct: 61 APILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRA 120
Query: 309 PLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRP 368
P PP RP + + + P ++ D + S P P
Sbjct: 121 AAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPP 180
Query: 369 --------PPAPLPPHDS--PPHKRRKGFP 388
PP PLP H S P + R K P
Sbjct: 181 PPGRRANAPPTPLPMHSSKAPAYNREKPLP 210
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 77.4 bits (189), Expect = 2e-14
Identities = 70/228 (30%), Positives = 86/228 (37%), Gaps = 61/228 (26%)
Query: 157 SEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPP----PSALQPVQ 212
SED ED D+ A ++ E + +G ++++PP PS +Q
Sbjct: 353 SEDDDEDDSDDSEAEKQSQKQHKEE------SHSDGTSTASSQQQAPPQSVPPSQIQAPP 406
Query: 213 LPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANA 272
+P PPPAPPL PP P + P PP PP PP
Sbjct: 407 MPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPP--------------------- 445
Query: 273 IRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPP---PPPPPPR---PVLPP 326
G+ L L LLP PG P P P P PP PP PPPR P LPP
Sbjct: 446 ----------GMPGLRGPLPRLLP--PGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPP 493
Query: 327 PAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLP 374
PAP P P + +V A G+ PPAPLP
Sbjct: 494 PAPPGIPPPRPGMMRPPLVPPLGPAPPGLF------------PPAPLP 529
Score = 59.3 bits (142), Expect = 6e-09
Identities = 69/283 (24%), Positives = 90/283 (31%), Gaps = 84/283 (29%)
Query: 89 EKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGA-GAGAEEPPAAPSSQPP-P 146
EK ++ H + A S ++ ++ + AP G PP AP +PP P
Sbjct: 367 EKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGP 426
Query: 147 PSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPS 206
P+ P P P A P P P P P
Sbjct: 427 PTGLP-------------------------PGPPPGAPPFLRP-----PGMPGLRGPLPR 456
Query: 207 ALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQ 266
L P PPP PP PPP P + P PP PPPR PP P
Sbjct: 457 LLPP--------GPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIP-------- 500
Query: 267 QETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPP----PPPPPPRP 322
P PG L PPL P P PP P P P
Sbjct: 501 -----------------------------PPRPGMMRPPLVPPLGPAPPGLFPPAPLPNP 531
Query: 323 VLPPPAPKVEITPEPVSVVAAVVD---GAVVAARGVIIAPRSE 362
+ P + P+ AA ++ A ++A+ I P++E
Sbjct: 532 GVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAE 574
Score = 54.7 bits (130), Expect = 1e-07
Identities = 64/226 (28%), Positives = 76/226 (33%), Gaps = 84/226 (37%)
Query: 158 EDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLA 217
E+ ED D S S+A S + S G ++ PP ++ P Q+
Sbjct: 350 EEFSEDDDEDDSDDSEAEKQSQKQHKEES---HSDGTSTASSQQQAPPQSVPPSQIQ--- 403
Query: 218 LSPPPPAPPLPPPPPLAQVAPSPPSPP-PPPRPPPTLSASDP--SLDFLRAQQETANAIR 274
APP+P PPPL PP+PP PP PP L P + FLR
Sbjct: 404 ------APPMPGPPPLGP----PPAPPLRPPGPPTGLPPGPPPGAPPFLRPP-------- 445
Query: 275 ELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEIT 334
G+ L L LLP PG PPP PP PPP PP P LPP
Sbjct: 446 --------GMPGLRGPLPRLLP--PG------PPPGRPPGPPPGPP-PGLPPG------- 481
Query: 335 PEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
PPP PP PP
Sbjct: 482 ---------------------------------PPPRGPPPRLPPP 494
Score = 48.9 bits (115), Expect = 8e-06
Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 5/87 (5%)
Query: 308 PPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVV-DGAVVAARGVI---IAPRSEE 363
PP+P PPP PPP P L PP P + P P + + RG + + P
Sbjct: 405 PPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP 464
Query: 364 GAPRPPPAPLPPHDSPPHKRRKGFPTR 390
G P P P P PP PP +G P R
Sbjct: 465 GRP-PGPPPGPPPGLPPGPPPRGPPPR 490
Score = 34.3 bits (77), Expect = 0.20
Identities = 17/30 (56%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 293 ALLPLLPGTPVDSLPPPLPPPPPPPPPPRP 322
++LPLL G V LPP PP PPP PP P
Sbjct: 181 SILPLL-GHGVPRLPPGRKPPGPPPGPPPP 209
Score = 32.7 bits (73), Expect = 0.59
Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 22/111 (19%)
Query: 289 EALSALLPLLPGTPVDSLPPPLPPPPPPPPP---PRPVLPPPAPKVEITPEPVSVVAAVV 345
E S LP +P P + L +P P PP PP V I P
Sbjct: 135 EVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILP---------- 184
Query: 346 DGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGF----PTRKR 392
+ GV P + P PPP P PP + R+ GF P R+R
Sbjct: 185 ----LLGHGVPRLPPGRK-PPGPPPGPPPPQVVQMYGRKVGFALDLPPRRR 230
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 77.0 bits (188), Expect = 3e-14
Identities = 89/295 (30%), Positives = 107/295 (36%), Gaps = 49/295 (16%)
Query: 123 GVAAPGAGAGAEEPPAAPS-------SQPPPPSACPQRYVLSEDRREDRRADTSAHSKAG 175
G+ +P A PP AP PP P A P L+ + A + H
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA-LAVHLLQA 663
Query: 176 SSSPEPWARPSCTPQEGGCPRPKERESPPPSALQP-VQLPRLALSPPPPA-PPLPP---- 229
SP P + P P P + PPS P + P L + P PPA PP+ P
Sbjct: 664 PFSPPP-SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
Query: 230 ----PPPLA----QVAPSPPSPPP-------PPRPPPTLSA-------SDP-SLDFLRAQ 266
PPPLA QV PSPP+ PP PPR PP L+A S P SL
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782
Query: 267 QETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVL-- 324
+ A LA Q L + P P + P PPP PP P+L
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
Query: 325 PPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSP 379
PP P P D +V R + AP PPP PP SP
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL------APGPPP---PPSRSP 888
Score = 74.3 bits (181), Expect = 2e-13
Identities = 78/291 (26%), Positives = 113/291 (38%), Gaps = 40/291 (13%)
Query: 122 PGVAAPGAGAGAEE--PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAH-------- 171
P +A AG E P APS++P PP+ P++ V S +A
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
Query: 172 -----SKAGSSSPEPWARPSCT-PQEGGCPR-PKERESPPPSALQPVQLPRLALSPPPPA 224
S++ SSS P + P+ + P G PR P P P LQ ++ P++ A
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 225 PPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGL 284
P L P PSP P PPP +A+ P L A + LA
Sbjct: 294 PALGPLSSSPLATPSPSGTKARPVPPPD-NAATPLPATLPPSPPLATPL-PLAPPSPSAP 351
Query: 285 AKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPP-------PAPKVEITPEP 337
L LP P TP PP + PP PP +PP +P ++ P P
Sbjct: 352 PSLQ-----TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Query: 338 VSV-----VAAVVDGAVVAARGVI-IAPRSEEGAPRPP--PAPLPPHDSPP 380
+++ ++ + A + ++PR + + P PA PP DSPP
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP-DSPP 456
Score = 69.3 bits (168), Expect = 6e-12
Identities = 89/324 (27%), Positives = 123/324 (37%), Gaps = 55/324 (16%)
Query: 96 HSTQGAGPAAEDAFSA-------EEETIFAILGPGVAAPGAGAGAEEPPAAPS--SQPPP 146
HST PAA SA ++ + P + +G A P AP+ SQP P
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 147 PSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGG-CPRPKERESPPP 205
R R+D A G S P A PS + + P P +P P
Sbjct: 275 KGLQALRPPQVTPPRKD------AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328
Query: 206 SALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPP----PTLSASDPSLD 261
+ L P P LA +P P APP P PP Q PSPP+ PP PP P + A PSL
Sbjct: 329 ATLPPS--PPLA-TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA-PPSLQ 384
Query: 262 FLRAQQ-------------ETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPP 308
+ Q + A+ L T G L +A + L + P SL
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL-QATHSFLTMSPRQTQASLTS 443
Query: 309 PLPP---PPPPPPPPRPVLPPPAPKVE-------------ITPEPVSVVAAVVDGAVVAA 352
P P PP PP P+ P +P ++ +T P+ ++++ + A
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503
Query: 353 RGVIIAPRSE-EGAPRPPPAPLPP 375
+I P E + + PP PP
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPP 527
Score = 68.6 bits (166), Expect = 1e-11
Identities = 75/266 (28%), Positives = 89/266 (33%), Gaps = 48/266 (18%)
Query: 126 APGAGAGAEEPPAAPSSQPPP-PSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWAR 184
AP A P P + PP P+ CP + + P P
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQ-----------------------APPSPLTT 578
Query: 185 PSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQ---VAPSPP 241
P P E P +PPP A + P L P PP PL PPP A P
Sbjct: 579 P---PPE----TPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 242 SPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEA---LSALLPLL 298
+PP PP PP + PS Q A A+ L + +A A P+
Sbjct: 632 APPSPPASPPLSPLATPS-----PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 299 P-GTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVII 357
P TP PP L PP PP P PP +P TP P + V
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA--TPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 358 APRSEEGAPRPPPAPL---PPHDSPP 380
P S P P PL PP PP
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPP 770
Score = 67.0 bits (162), Expect = 3e-11
Identities = 80/285 (28%), Positives = 99/285 (34%), Gaps = 33/285 (11%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVL-SEDRREDRRADTSAHSKAGSSSPE 180
P +AP + PPA P SQ PP P S + S S + + P
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405
Query: 181 PWARPSCTPQEG-GCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPS 239
P A S G P + S + P Q SP PA P PPL
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSF--LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 240 PPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLP 299
P SPP P +S L Q ++ A L + E S+L P
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 300 GTPVDSLPPP-------LPPPP---------------PPPPPPRPVLPPPAPKVEITPEP 337
TP SL P L PPP PP P P P+ PP+P PE
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
Query: 338 VSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPL--PPHDSPP 380
S +A A A +A +G P PP +PL PP +PP
Sbjct: 584 PSSIATPPPQAPPA-----LASPPLQGLPSPPLSPLATPPPQAPP 623
Score = 61.2 bits (147), Expect = 2e-09
Identities = 77/277 (27%), Positives = 102/277 (36%), Gaps = 22/277 (7%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYV---LSEDRREDRRADTSAHSKAGSSS 178
P P A + PP+ P+S P PSA P V L+ + + ++ + +
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Query: 179 PEPWARPS-CTPQEGGCPRPKERESPPPSALQP-VQLPRLALSPPPPAPPLPPPPPLAQV 236
P P A P+ TP P P P + P LP L+ PPP P PL QV
Sbjct: 784 PPPQAPPALATPPLQALPSPPA-SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
Query: 237 APSPPSPPP------PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLR-QGLAKLSE 289
PSPP+ P PP P P S S P L A R + TL LA S
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 290 ALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPP------PAPKVEITPEPVSVVAA 343
+ ++ L G DS P PPP P PAP + P + +
Sbjct: 903 SATSTPEELRG--YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 960
Query: 344 VVDGAVVAARGVIIAPRSE-EGAPRPPPAPLPPHDSP 379
+A G+ +E + P P L P SP
Sbjct: 961 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997
Score = 38.9 bits (89), Expect = 0.008
Identities = 85/362 (23%), Positives = 106/362 (29%), Gaps = 104/362 (28%)
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQ------------RYVLSEDRR------- 161
G P A A P P S PPP P R L+E
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
Query: 162 EDRRADTSAHSKAGSSSPEPWARPSCT-------PQEGGCPRP----------------- 197
+ AG+SS P +RP + P + P P
Sbjct: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 198 ---------------KERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA----- 237
K E+P SAL R S P P P P ++ A
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAG--ARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 238 ---PSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAK-LSEALSA 293
P+P + P PP P S S S A G L++ ++ LS + +
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 294 LL------PLLPGTPVDSLPPPLPPP-------PPPPPPPR----PVLPPPAPKVEITPE 336
L P GTP P P P PP PPR P L P + TP
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 337 PVSVVAAVV---DGAVV-----------AARGVIIAPRSEEGAPR----PPPAPLPPHDS 378
P A V D A A + +AP S P P P PP +
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368
Query: 379 PP 380
PP
Sbjct: 369 PP 370
Score = 35.4 bits (80), Expect = 0.092
Identities = 43/157 (27%), Positives = 54/157 (34%), Gaps = 17/157 (10%)
Query: 241 PSPPPPPRPPPTLSASDPSLDFLRAQQETA-NAIRELAGTLRQGLAKLSEALSALLPLLP 299
P PP PRPPP ++ + +L L A + E AG + G A + E+ P
Sbjct: 27 PRPPGSPRPPPPVTPA--ALRVLGAAGAVGRKPLAERAGGI--GGATIPESAPRAGPTRS 82
Query: 300 GTPVDSLPPPLPP--------PPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVA 351
P PP PP P PV P P P+ +
Sbjct: 83 AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 142
Query: 352 ARG-VIIAPRS---EEGAPRPPPAPLPPHDSPPHKRR 384
ARG AP+ GA R P P SP RR
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Score = 34.7 bits (78), Expect = 0.16
Identities = 27/98 (27%), Positives = 36/98 (36%), Gaps = 10/98 (10%)
Query: 301 TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKV-----EITPEPVSVVAAVVDGAVVAARGV 355
TP P L P PP P P P + P A +V + +P++ A + GA +
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 356 IIAPRSEEGAPRPPPAPLPP-----HDSPPHKRRKGFP 388
P G PA PP +PP K P
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113
Score = 32.7 bits (73), Expect = 0.59
Identities = 34/133 (25%), Positives = 44/133 (33%), Gaps = 32/133 (24%)
Query: 118 AILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS 177
++ GP + A P +PSS P D + HS + +S
Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGP-------------------DLAGHSSSATS 906
Query: 178 SPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA 237
+PE P+ G SPPP A LA P P PP + A
Sbjct: 907 TPEELRGYDSGPEGGAA------ASPPPDA-------ELAACHPAAWSRGPAPPLAFRGA 953
Query: 238 PSPPSPPPPPRPP 250
P P P PP P
Sbjct: 954 PGAPLPWPPATGP 966
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 76.6 bits (187), Expect = 4e-14
Identities = 78/309 (25%), Positives = 112/309 (36%), Gaps = 30/309 (9%)
Query: 82 DFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPS 141
D + EKL RV H Q P+ +++ E E F L P E +
Sbjct: 621 DINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRE-----LERYVTSCL 675
Query: 142 SQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQ--EGGCPRPKE 199
+ P A + + + + S S SSS + P+ + G P ++
Sbjct: 676 RKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQ 735
Query: 200 RESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPP----PTLSA 255
++ Q Q P PPP P PPPPP Q PP PPPPP P P + +
Sbjct: 736 KKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKS 795
Query: 256 SDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPP 315
S P F+ Q +L G++ + ++ + L P LPP LP PP
Sbjct: 796 SPP--PFIATQVPVLEP--QLPGSVFDPIGHFTQPILHL-------PQPELPPHLPQPPE 844
Query: 316 PPPPP----RPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPA 371
PP V+ PPA + +P AR ++P + P
Sbjct: 845 HSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSP----ALTQTPLL 900
Query: 372 PLPPHDSPP 380
P PP PP
Sbjct: 901 PQPPMAQPP 909
Score = 73.2 bits (178), Expect = 4e-13
Identities = 82/315 (26%), Positives = 100/315 (31%), Gaps = 105/315 (33%)
Query: 134 EEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGG 193
++PP P PPPP PQ+ P P P PQ+
Sbjct: 755 QQPPPPPQQPPPPPP--PQQ----------------------QQQPPPPPPPPSMPQQAA 790
Query: 194 CPRPKERESPPP---------------SALQPV--------QLPRLALSPPPPAPP---L 227
P + SPPP S P+ LP+ L P P PP
Sbjct: 791 ---PAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHST 847
Query: 228 PP---------PPPLAQVAPSPPS---------PPPPPRPP------------PTLSASD 257
PP PP L P PS PP P RPP P +
Sbjct: 848 PPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQ 907
Query: 258 PSLDFLRAQQETANAIRELAGTLR-QGLAKLSEALSALLPLLPGTPVDSLPPPLPPPP-- 314
P L ++ A + + L Q L K+ PLLP V S PPP PPP
Sbjct: 908 PPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT----PLLPSVKVQSQPPPPLPPPPH 963
Query: 315 ----------PPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEG 364
PPPPPP PPP + + P PV + + P +
Sbjct: 964 PSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQP-----PPPQGQQ 1018
Query: 365 APRPPPAPLPPHDSP 379
P PPP PP P
Sbjct: 1019 PPHPPPGQQPPPPQP 1033
Score = 52.0 bits (123), Expect = 9e-07
Identities = 75/292 (25%), Positives = 93/292 (31%), Gaps = 62/292 (21%)
Query: 136 PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCP 195
P SQPPPP P S + P P P PQ P
Sbjct: 946 PSVKVQSQPPPPLPPPPH--------------PSVQQQLQQQPPPP---PPPQPQ----P 984
Query: 196 RPKERESPPPSA--LQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTL 253
P+++ PPP LQP+Q PPPP PP PP P PPP P P +
Sbjct: 985 PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPP-----PGQQPPPPQPAKPQQV 1039
Query: 254 SASDPSLDFLRAQQETANAIRELAGTL-------------------RQGLAKLSEALSAL 294
S ++ + +RE L +Q + + L A
Sbjct: 1040 IQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAA 1099
Query: 295 LPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPK-VEITPEPVSVVAAVVDGAVVAAR 353
+ P V + P P P L P PK E PV + V R
Sbjct: 1100 SVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGR 1159
Query: 354 GVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTR-------KRRGRWKS 398
VI P E+ AP PP AP D K+ P K G W S
Sbjct: 1160 PVIRPP--EQNAP-PPGAP----DKDKQKQEPKTPVAPKKDLKIKNMGSWAS 1204
Score = 50.8 bits (120), Expect = 2e-06
Identities = 48/190 (25%), Positives = 66/190 (34%), Gaps = 33/190 (17%)
Query: 178 SPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLA--LSPPPPAPPLPPPPPLAQ 235
S P + TP + P+P +PPP P P + L P + PP PL
Sbjct: 194 STVPNTTQASTPPQTQTPQP----NPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT 249
Query: 236 VAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQ-ETANAIRELAGTLRQGLAKLSEALSAL 294
P PP P PPP P P S P + Q +T ++ A T
Sbjct: 250 PPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP------------ 297
Query: 295 LPLLPGTPVDSL--PPPLPPPPPPP------PPPRPVLPPPAPKVEITPEPVSVVAAVVD 346
T +D + PP LPP P RPV PP + P ++ V
Sbjct: 298 ------TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
Query: 347 GAVVAARGVI 356
+ G++
Sbjct: 352 EQLKCCSGIL 361
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 46/170 (27%)
Query: 225 PPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGL 284
P + P Q + P + P P PPP + P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP-------------------------- 224
Query: 285 AKLSEALSALLP-LLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVS---V 340
A+ P L+ TPV ++ PP P PPP PP+P PPPAP P+PV
Sbjct: 225 ------FPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP-QPPPAP----APQPVQSHPP 273
Query: 341 VAAVVDGAVVAARGV-----IIAPRSEEGAPRPPPAPLPPHDSPPHKRRK 385
+ A V +GV P + + PP P P + +RR+
Sbjct: 274 IIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRE 323
Score = 38.1 bits (87), Expect = 0.014
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 5/97 (5%)
Query: 298 LPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVII 357
+P T S PP P P PPP V P P +TP+ +V V V
Sbjct: 196 VPNTTQASTPPQTQTPQPNPPP---VQATPHPFPAVTPD--LIVQTPVMTVVPPQPLQTP 250
Query: 358 APRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRG 394
P + P P PAP P PP P + ++G
Sbjct: 251 PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG 287
Score = 36.2 bits (82), Expect = 0.054
Identities = 38/146 (26%), Positives = 56/146 (38%), Gaps = 25/146 (17%)
Query: 124 VAAPGAGAGAEEPPAAPSSQPPPPS-ACPQRYVLSEDRREDRRAD--TSAHSKAGSS--- 177
+ P G + P P QPPPP A PQ+ + ++D ++ H + S
Sbjct: 1008 IQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLM 1067
Query: 178 --SPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPP----- 230
SP+ S T Q SPP +QP + A S P P +
Sbjct: 1068 IHSPQMSQFQSLTHQ-----------SPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIH 1116
Query: 231 PPLAQVAP-SPPSPPPPPRPPPTLSA 255
P+ + P SP P PP+ P ++ A
Sbjct: 1117 SPIIRSEPFSPSLRPEPPKHPESIKA 1142
Score = 35.8 bits (81), Expect = 0.070
Identities = 22/81 (27%), Positives = 25/81 (30%), Gaps = 38/81 (46%)
Query: 302 PVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRS 361
PV PPP P PPPPPPP+ PP P
Sbjct: 752 PVPQQPPPPPQQPPPPPPPQQQQQPPPP-------------------------------- 779
Query: 362 EEGAPRPPPAPLPPHDSPPHK 382
PPP +P +P K
Sbjct: 780 ------PPPPSMPQQAAPAMK 794
Score = 32.0 bits (71), Expect = 1.0
Identities = 32/153 (20%), Positives = 56/153 (36%), Gaps = 33/153 (21%)
Query: 134 EEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGG 193
+ PP P PPP+ PQ +H +++P+P + G
Sbjct: 248 QTPPPVPPQPQPPPAPAPQ--------------PVQSHPPIIAATPQP------VKTKKG 287
Query: 194 CPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTL 253
R + ++ P+ + P+ PP PP P L Q S PP + P
Sbjct: 288 VKR--KADTTTPTTIDPIH-------EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD- 337
Query: 254 SASDPSLDFLRAQQETANAIRELAGTLRQGLAK 286
S P+ + + + ++ +G L++ AK
Sbjct: 338 SQQHPAPE---KSSKVSEQLKCCSGILKEMFAK 367
Score = 30.8 bits (68), Expect = 2.3
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 11/87 (12%)
Query: 208 LQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQ 267
LQ V R A P P P+ VA S P+ PPP + S+SD S D +
Sbjct: 446 LQDVFEMRFAKMPDEPEEPV--------VAVSSPAVPPPTKVVAPPSSSDSSSD---SSS 494
Query: 268 ETANAIRELAGTLRQGLAKLSEALSAL 294
++ ++ + Q LA+L E L A+
Sbjct: 495 DSDSSTDDSEEERAQRLAELQEQLKAV 521
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 76.3 bits (186), Expect = 5e-14
Identities = 59/202 (29%), Positives = 65/202 (32%), Gaps = 52/202 (25%)
Query: 132 GAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQE 191
GA P P PP P L + E++ + S E TP
Sbjct: 454 GASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSG 513
Query: 192 GGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPP----P 247
G P P P L P P +PPPP PPLP P + PS P PP P
Sbjct: 514 GDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPP-PPLPGLPSPQEAPPSAPPQAPPLPGSP 572
Query: 248 RPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLP 307
PPP P LPG LP
Sbjct: 573 EPPPA-------------------------------------------PPLPG----DLP 585
Query: 308 PPLPPPPPPPPPPRPVLPPPAP 329
PP PPPPPPP PV PPP P
Sbjct: 586 PPPPPPPPPPGTDGPVPPPPPP 607
Score = 68.9 bits (167), Expect = 7e-12
Identities = 64/214 (29%), Positives = 81/214 (37%), Gaps = 52/214 (24%)
Query: 74 QEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSA--------EEETIFAIL-GPGV 124
+E++ F T +R P + A PAA SA EE+ + IL GPG
Sbjct: 438 KELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGD 497
Query: 125 A--------APGAGAGAEEP-PAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAG 175
A A +G + P P P+ P P A
Sbjct: 498 AVSIEILPVAVATPSGGDAPTPGVPTGSPSP-------------------------DLAP 532
Query: 176 SSSPEPWARPSCTPQEGGCPRPKER------ESPP-PSALQPVQLPRLALSPPPPAPPLP 228
++ P P A P P G P P+E ++PP P + +P P L PPP PP P
Sbjct: 533 AAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPP 592
Query: 229 PPPPLAQVAPSPPSPPPPP--RPPPTLSASDPSL 260
PPP P PP PPPPP PP L D L
Sbjct: 593 PPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSEL 626
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/163 (30%), Positives = 61/163 (37%), Gaps = 30/163 (18%)
Query: 243 PPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPL----- 297
PP P + PP +L+ + E IR L G G A E L +
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGP---GDAVSIEILPVAVATPSGGD 515
Query: 298 --LPGTPVDSLPPPL------------PPPPPPP--PPPR---PVLPPPAPKVEITPEPV 338
PG P S P L PPPPP P P P+ P PP AP + +PEP
Sbjct: 516 APTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPP 575
Query: 339 SVVAAVVDGAVVAARGVIIAPRSEEG-APRPPPAPLPPHDSPP 380
A + G + P +G P PPP P PP PP
Sbjct: 576 P--APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 76.3 bits (186), Expect = 5e-14
Identities = 64/208 (30%), Positives = 83/208 (39%), Gaps = 31/208 (14%)
Query: 78 KRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPP 137
KR ++ +R E L + + D + I A+ P +A P + + PP
Sbjct: 1364 KRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPP 1423
Query: 138 AAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRP 197
AP++ P P P SA+S P +P TP P+P
Sbjct: 1424 LAPAAAVPGPPPLPGL--------------PSANSNGTPEPPLLEEKPPPTPPPAPTPQP 1469
Query: 198 KERESPPP-SALQPVQLPRLALSPP-PPAPPLPPPPPLAQVAPSPPSPPP--------PP 247
+ PPP P P +A +P PP PPLPPPPP A PSPP PPP PP
Sbjct: 1470 QPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAM--PSPPPPPPPAAAPLAAPP 1527
Query: 248 RPPPTLSASDPSLD-----FLRAQQETA 270
P S DP L L +QETA
Sbjct: 1528 EEPAAPSPEDPELPDTRPLHLAKKQETA 1555
Score = 74.3 bits (181), Expect = 2e-13
Identities = 59/209 (28%), Positives = 72/209 (34%), Gaps = 47/209 (22%)
Query: 162 EDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPP 221
++R S S + P A P T G P P P L + +P
Sbjct: 1390 KNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPE 1449
Query: 222 PPA-----PPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIREL 276
PP PP PPP P Q P PP PPPPP+P
Sbjct: 1450 PPLLEEKPPPTPPPAPTPQ--PQPPPPPPPPQP--------------------------- 1480
Query: 277 AGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPE 336
AL + PL+ TP PPPLPPPPPP P P PPPA P
Sbjct: 1481 -------------ALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527
Query: 337 PVSVVAAVVDGAVVAARGVIIAPRSEEGA 365
+ D + R + +A + E A
Sbjct: 1528 EEPAAPSPEDPELPDTRPLHLAKKQETAA 1556
Score = 68.6 bits (166), Expect = 1e-11
Identities = 73/263 (27%), Positives = 86/263 (32%), Gaps = 89/263 (33%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPS-------------------ACPQRYV-LSEDRR 161
P V A G +PPA P+ PPPS CP L E+ +
Sbjct: 1315 PSVPARGL---QPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELK 1371
Query: 162 ------------------EDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESP 203
++R S S + P A P T G P P
Sbjct: 1372 RNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP 1431
Query: 204 PPSALQPVQLPRLALSPPPP-----APPLPPPPPLAQVAPSPPSPPPPPRP----PPTLS 254
P L + +P PP PP PPP P Q P PP PPPPP+P PP L
Sbjct: 1432 GPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ--PQPPPPPPPPQPALPSPPPLV 1489
Query: 255 ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLP-PP 313
A PS S P LP P PP +P PP
Sbjct: 1490 APTPS--------------------------------SPPPPPLPPPP----PPAMPSPP 1513
Query: 314 PPPPPPPRPVLPPPAPKVEITPE 336
PPPPP P+ PP +PE
Sbjct: 1514 PPPPPAAAPLAAPPEEPAAPSPE 1536
Score = 68.6 bits (166), Expect = 1e-11
Identities = 59/198 (29%), Positives = 68/198 (34%), Gaps = 68/198 (34%)
Query: 197 PKERESP--PPSALQPVQLPRLALSPPPPAPPLP-------PPPPLAQVAPSPPSPPPPP 247
PK+ +P PP A P A+ PPP P LP P PPL + P PP+PPP P
Sbjct: 1413 PKDTSTPDGPPLA------PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP-PPTPPPAP 1465
Query: 248 RPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLP 307
P P P P P P
Sbjct: 1466 TPQPQPPPPPP----------------------------------------PPQPALPSP 1485
Query: 308 PPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPR 367
PPL P P PPP P+ PPP P + P P AA + AP E AP
Sbjct: 1486 PPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAA-----------PLAAPPEEPAAPS 1534
Query: 368 PPPAPLPPHDSPPHKRRK 385
P L P P H +K
Sbjct: 1535 PEDPEL-PDTRPLHLAKK 1551
Score = 63.9 bits (154), Expect = 2e-10
Identities = 63/235 (26%), Positives = 78/235 (33%), Gaps = 96/235 (40%)
Query: 221 PPPAPP--LPPPPPLAQVAPSPPSPPPPPRPPPT------------------LSASDPSL 260
PP +PP +PP P + P PP+ P P PPP+ L P
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCK 1364
Query: 261 DFLRAQQETANAIRELAGTLRQGLAK-------LSEALSAL------------------- 294
+ + + +AK +S A+SAL
Sbjct: 1365 RLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPL 1424
Query: 295 -----------LPLLP-----GTP----VDSLPPPLPP--------PPPPPPPPRPVLPP 326
LP LP GTP ++ PPP PP PPPPPPPP+P LP
Sbjct: 1425 APAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS 1484
Query: 327 PAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPA-PLPPHDSPP 380
P P V TP +P P PPPA P PP PP
Sbjct: 1485 PPPLVAPTPS---------------------SPPPPPLPPPPPPAMPSPPPPPPP 1518
Score = 56.2 bits (134), Expect = 5e-08
Identities = 78/285 (27%), Positives = 94/285 (32%), Gaps = 82/285 (28%)
Query: 86 RTKEKLARVPHSTQGAGP---AAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSS 142
RT+++ + H Q P + D E+ A G G G+G GA PP P
Sbjct: 635 RTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLG----GSG-GAGGPPGTPYE 689
Query: 143 QPPPPSACPQRYVLSEDRREDRRADTSAHS----------------KAGSSSPEPWARP- 185
PQRY L R D A + + G +PE A
Sbjct: 690 LAKED---PQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSV 746
Query: 186 ---SCTPQEGGCPRPKERESPPPSALQPVQLPR-LALSPPPPAPPLPPPPPLAQVAPSPP 241
+E G K PPP+A P L L P PL PPP Q+ PS
Sbjct: 747 VHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVL 806
Query: 242 SPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGT 301
S P P P SAS + L P T
Sbjct: 807 SHAPSPSP----SASKVGVHLLE----------------------------------PAT 828
Query: 302 PVDSLPPPLPPPPPPPPPPRPV----------LPPPAPKVEITPE 336
D P P PPPPPPPPPP P+ L P AP + PE
Sbjct: 829 R-DGAPQP-PPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE 871
Score = 51.2 bits (121), Expect = 2e-06
Identities = 70/269 (26%), Positives = 93/269 (34%), Gaps = 53/269 (19%)
Query: 144 PPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESP 203
PPPP P VLS + + + SK G EP R PQ P P P
Sbjct: 796 PPPPQLLPS--VLSH-----APSPSPSASKVGVHLLEPATRDGA-PQ----PPPPPPPPP 843
Query: 204 PPSALQ-PVQLPRLALSPPPPAPPLPPP----PP------LAQVAPSPPSPPPPPRPPPT 252
PP LQ L L P P+P L P PP L + P PP+P PP
Sbjct: 844 PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPN 903
Query: 253 LSASDPSLDFLRAQQETANAIRELAGT-LRQGLAKLSEALSALLPLLP------------ 299
DP+ + + A R + T + + L + + P +
Sbjct: 904 SEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYG 963
Query: 300 --GTPVDSLPPPLPPPPPPPPPPR----PVLP-------PPAPKVEITPEPVSVVAAVVD 346
G P D P PPP PP P P P P + + P + + V+
Sbjct: 964 KAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVN 1023
Query: 347 GAVVAARGVIIAPRSEEGAPRPPPAPLPP 375
+ +I + AP PPP P PP
Sbjct: 1024 AEPLG----LIQSGPHQAAPPPPPPPPPP 1048
Score = 50.8 bits (120), Expect = 2e-06
Identities = 99/422 (23%), Positives = 129/422 (30%), Gaps = 149/422 (35%)
Query: 100 GAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEE-----------PPAAPSSQPPPPS 148
GAG A A+S + +LGP G G G + PP PS PPP
Sbjct: 434 GAGGAGGQAYSPGQPQ--GLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGL 491
Query: 149 ACPQRYVLSEDRREDRRADT--------SAHSKA-------------------------- 174
A Q Y S D+ + + +AHS+
Sbjct: 492 ATCQSY--SPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWG 549
Query: 175 -------GSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPP------ 221
G +SP RP +P G P P L V L+PP
Sbjct: 550 PSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYA 609
Query: 222 ---------------------PPAPPLPPPPPLAQVAPSPPSPPP--------------- 245
PPA L Q PSPP
Sbjct: 610 AGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAAD 669
Query: 246 -------------PPRPPPTLSASDPSLDFLRAQQETANAIRELA-GTLRQGLAKLSEAL 291
PP P L+ DP L++ T+ ++ E A L GL +L E
Sbjct: 670 ASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKK 729
Query: 292 S------------ALLPLLPGTPVDSLPPPLPPPPPPPPP------PRP----------- 322
A + G L L PPPPPP P P
Sbjct: 730 KGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPD 789
Query: 323 ---VLPPPAPKVEITPEPVSVVAAVVDGAVVAARGV-IIAPRSEEGAPRPPPAPLPPHDS 378
VLPPP P ++ P +S + A + GV ++ P + +GAP+PPP P PP
Sbjct: 790 LPLVLPPPPP--QLLPSVLSHAPSPSPSA--SKVGVHLLEPATRDGAPQPPPPPPPPPPP 845
Query: 379 PP 380
P
Sbjct: 846 MP 847
Score = 43.9 bits (102), Expect = 3e-04
Identities = 43/150 (28%), Positives = 53/150 (35%), Gaps = 22/150 (14%)
Query: 185 PSCTPQEGGCPRPKE----RESPPPSALQPVQLPRLA----LSPPPPAPPLPPPPPLAQV 236
P +P G P + + S P+ + RLA L P P PP
Sbjct: 173 PPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPP-----Y 227
Query: 237 APSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLR--QGLAKLSEALSAL 294
P PP PPPPPR PT + L + A A + + L G A
Sbjct: 228 RPGPPDPPPPPRHLPT------QFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERA 281
Query: 295 LPLLPGTPVDSLPPPLPPPPPPPPPPRPVL 324
LP T + P PPPPPPP L
Sbjct: 282 LP-RQDTVIKHYQRPASAQPPPPPPPAHAL 310
Score = 42.7 bits (99), Expect = 6e-04
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 14/110 (12%)
Query: 119 ILGPGVAAPGAGAGAEEPPAAPS--SQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGS 176
+ G GV P A+ PP P PPPP P ++ L + ++A + A
Sbjct: 208 LAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNL-------LASSSAAAAAAEQ 260
Query: 177 SSPEPWARPSCTPQEGGCPRPKERESP-PPSALQPVQLPRLALSPPPPAP 225
SSP+ + P P P ER P + ++ Q P A PPPP P
Sbjct: 261 SSPQLYNFSGAAPG----PPPPERALPRQDTVIKHYQRPASAQPPPPPPP 306
Score = 42.4 bits (98), Expect = 7e-04
Identities = 44/166 (26%), Positives = 59/166 (35%), Gaps = 33/166 (19%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYV----------LSEDRREDRRADTSAH 171
PG G + PA P P R+V L +D E+R +
Sbjct: 894 PGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQD--EERSFFPTME 951
Query: 172 SKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPV-------------QLPRLAL 218
G + + + + P++ G P+ P P A P + P L L
Sbjct: 952 EMFGGGAADDYGKAG-PPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGL 1010
Query: 219 SPPPPAPPLPP-----PPPLAQVAPSPPSPPPP-PRPPPTLSASDP 258
P P P LP P L Q P +PPPP P PPP AS+P
Sbjct: 1011 DPNKP-PELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 40.8 bits (94), Expect = 0.002
Identities = 65/261 (24%), Positives = 87/261 (33%), Gaps = 64/261 (24%)
Query: 103 PAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRRE 162
P E+ F + GP AGA PP P+ P P CP R
Sbjct: 948 PTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPY-CPGR--------- 997
Query: 163 DRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQL----PRLAL 218
A + PE TP G P K E P +P+ L P A
Sbjct: 998 -----------ASGAGPE-------TPGLGLDPN-KPPELPSTVNAEPLGLIQSGPHQA- 1037
Query: 219 SPPPPAPPLPPPPPLAQVAPSPPSP----------------------PPPPRPPPTLSAS 256
+PPPP PP PPP P ++ SP PP + P L A
Sbjct: 1038 APPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQ 1097
Query: 257 DPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPP 316
+ + A ++ A+ ++ R+ L L + + L P +D PP P P
Sbjct: 1098 EYEFE---ADEDKADVPADIRLNPRR-LPDLVSSCRSRPALSPLGDIDF----CPPNPGP 1149
Query: 317 PPPPRPVLPPPAPKVEITPEP 337
P R P K + P P
Sbjct: 1150 DGPRRRGRKPTKAKRDGPPRP 1170
Score = 33.1 bits (74), Expect = 0.45
Identities = 40/148 (27%), Positives = 51/148 (34%), Gaps = 22/148 (14%)
Query: 180 EPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPS 239
+PW RP P P R A PV + +PPP A P PPP +
Sbjct: 1665 KPWHRP---------PVPVRRSG---QAKNPVSAGGSS-APPPKA---PAPPPKPETPEK 1708
Query: 240 PPSPPPPPRPPPTLSASDPSLD---FLRAQQETANAIRELAG--TLRQGLAKLSEALSAL 294
S PP + P T P+ + LR ++ + G LR A
Sbjct: 1709 TTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPE 1768
Query: 295 LPLLPGTPVDS-LPPPLPPPPPPPPPPR 321
L G P S LP P PPP+
Sbjct: 1769 RSLATGQPATSRLPKARPTKVKAEPPPK 1796
Score = 32.3 bits (72), Expect = 0.78
Identities = 48/195 (24%), Positives = 59/195 (30%), Gaps = 38/195 (19%)
Query: 197 PKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSAS 256
P P SAL Q P S P P P S S PP PP
Sbjct: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVP-------------SSLSLQDPPFSPPANGLL 183
Query: 257 DPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPP 316
P D L + A + G E L+ L P + PP P PP
Sbjct: 184 SPH-DVLHLKPSQAPTVPSSLGF---------ERLAGGGVLGPAGLGPAQTPPYRPGPPD 233
Query: 317 PPPPRPVLP----------PPAPKVEITPEPVSVVAAVVDGAVVAARGV-----IIAPRS 361
PPPP LP A E + + + G R + +I
Sbjct: 234 PPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQ 293
Query: 362 EEGAPRPPPAPLPPH 376
+ +PPP P P H
Sbjct: 294 RPASAQPPPPPPPAH 308
Score = 32.3 bits (72), Expect = 0.78
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 2/94 (2%)
Query: 288 SEALSALL-PLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVD 346
S ALSA P G+ +P L PP PP L P + + P V + +
Sbjct: 145 SSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSL- 203
Query: 347 GAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
G A G ++ P A PP P PP PP
Sbjct: 204 GFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPP 237
Score = 29.3 bits (64), Expect = 6.6
Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 8/44 (18%)
Query: 302 PVDSLPPPLPPPPPPPPPPRPVLP-------PPAPKVEIT-PEP 337
PV + PPP P PPP+P P PP E PEP
Sbjct: 1683 PVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEP 1726
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 74.3 bits (181), Expect = 2e-13
Identities = 80/301 (26%), Positives = 99/301 (32%), Gaps = 72/301 (23%)
Query: 117 FAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGS 176
FA++G G A P Q P + C ++++ + + + + S G
Sbjct: 126 FALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGK 185
Query: 177 SSPEPWARPSCTPQEGG--------------CPRPKERESPPPSALQPVQLPRLALSPP- 221
+ P + + PQ G P P PPP PR L PP
Sbjct: 186 AGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPG 245
Query: 222 PPAPPLPPPPPLAQVAPSPPSPPPPPR----PPPTLSASDPSLDFLRAQQETANAIRELA 277
PP PP PPPP QV P PP PP R PPP L P
Sbjct: 246 PPGPPGPPPP--GQVLP-PPLAGPPNRGDRPPPPVLFPGQP------------------- 283
Query: 278 GTLRQGLAKLSEALSALLPLLPGTPVDSL-PPPLPPPPPPPPPPRPVLPPPAPKVEITPE 336
+ LP P PV PPP PPPP PPP P PP P + P
Sbjct: 284 ---------FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPP 334
Query: 337 PVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSP---PHKRRKGFPTRKRR 393
+ +AP P P P PH +P P G PT R
Sbjct: 335 ------------------LTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSR 376
Query: 394 G 394
G
Sbjct: 377 G 377
Score = 67.8 bits (164), Expect = 2e-11
Identities = 63/232 (27%), Positives = 76/232 (32%), Gaps = 53/232 (22%)
Query: 122 PGVAAPG-------AGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKA 174
PG A PG AG PP P P PP P VL +
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPP--------LAGPPNR 269
Query: 175 GSSSP-------EPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPL 227
G P +P+ +P P G P P PPP P Q P P PP PP
Sbjct: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
Query: 228 PPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKL 287
P PPL +AP P P PPP PP +P+ F + + G
Sbjct: 330 PLGPPLT-LAPPPHLPGPPPGAPPPAPHVNPA--FFPPPTNSGMPTSDSRG--------- 377
Query: 288 SEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVS 339
PPP P PPP R PP +++ P+S
Sbjct: 378 -------------------PPPTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410
Score = 32.3 bits (72), Expect = 0.78
Identities = 33/131 (25%), Positives = 35/131 (26%), Gaps = 33/131 (25%)
Query: 120 LGPGVAAPGAGAGAEE-PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSS 178
L PG P G G PP PPPP P R
Sbjct: 292 LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR------------------------P 327
Query: 179 PEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSP--------PPPAPPLPPP 230
P P P P P PP + P P S PPP P P
Sbjct: 328 PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP 387
Query: 231 PPLAQVAPSPP 241
PP + PP
Sbjct: 388 PPYDRGDYGPP 398
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 74.3 bits (181), Expect = 2e-13
Identities = 75/293 (25%), Positives = 98/293 (33%), Gaps = 49/293 (16%)
Query: 122 PGVAAPGAGAGAEEP-----PAAPSSQPPPPS---ACPQRYVLSEDRREDRRADTSAHSK 173
P P G P P P++ PP P A P S A T K
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-----SPKGAPTTPAATPPSPK 1252
Query: 174 AGSSSPEPWARPS-------------CTPQEGGCPRPKERESPPPSALQPVQLPRLALSP 220
G ++P P P+ TP G P P P P P+ A +P
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312
Query: 221 PPPAPPLP---PPPPLAQVAPSPPS-PPPPPRPPPTLSASDPSLDFLRAQQETANAIREL 276
P PP P P P + AP+PP+ PP P+ PTL A+ PS
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS----------------S 1356
Query: 277 AGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPE 336
G +K A P G P + P P P P P P P P ++P+
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP---LSPK 1413
Query: 337 PVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPT 389
+GA ++G + P + + PA P P KG PT
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT 1466
Score = 70.1 bits (170), Expect = 3e-12
Identities = 77/294 (26%), Positives = 96/294 (32%), Gaps = 41/294 (13%)
Query: 123 GVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPW 182
G+ A + GA PPAA P A P + A + ++ P P
Sbjct: 929 GIPASPSPKGAPTPPAATPPSPKGGPATP--------------SPKWAPTPPAATPPSPK 974
Query: 183 ARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPS 242
P+ TP G P P P P P+ A +PP PP P P A P S
Sbjct: 975 GGPA-TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 243 PPPPPRPP-PTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGT 301
PP PP P S + L A G L +A P G
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093
Query: 302 PVDSLPPPLPPPP---PPPP------------PPRPVLPPPAPKVEI-TPEPVSVVAAVV 345
P P P PP PP P P P PP+PK + TP P
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP-------- 1145
Query: 346 DGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
GA +P+ P P AP P +PP + G T +G +P
Sbjct: 1146 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP-SPKGGLATPSPKGAPTTP 1198
Score = 68.2 bits (165), Expect = 1e-11
Identities = 91/321 (28%), Positives = 111/321 (34%), Gaps = 62/321 (19%)
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE 180
GP +P GA PPAA P A P A T K G ++P
Sbjct: 1093 GPATPSP---KGAPMPPAATPPSPKGGLATPPH-----KGAPTTPAATPPSPKGGLATPP 1144
Query: 181 PWARPS-------------CTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPL 227
P P+ TP G P P P P+ A + P PP
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 228 P------PPPPLAQVAP--SPPSP------PPPPRPPPTLSASDPSLDFLRAQQETANAI 273
P P P A P +PPSP P P P T +A+ PS A A
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264
Query: 274 RELAGT---LRQGLA----KLSEALSALLPLLP-GTPVDSLPPPLPPPP---PPPPPPRP 322
A T L+ GLA K + + + P P G P S P P PP PP P P
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 323 VLPPP--APKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHD--- 377
PPP AP P + +++G P S+EG PPA P H
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP--TPPAATPSHKGGP 1382
Query: 378 --SPPHKRR-------KGFPT 389
+PP +R KG PT
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPT 1403
Score = 65.5 bits (158), Expect = 8e-11
Identities = 74/288 (25%), Positives = 102/288 (35%), Gaps = 35/288 (12%)
Query: 132 GAEEPPAAPSSQPPP-------PSAC----PQRYVLSEDRREDRRADTSAHSKAGSSSPE 180
G+++ PA S PP PSA P+ L K G ++P
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 181 PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLP---PPPPLAQVA 237
P P+ + P+ K R +P P + P+ A +PP PP P P P + A
Sbjct: 905 PKQAPALS-MTSSSPK-KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 238 PSPPSPPP------PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEAL 291
P+PP+ P P P P + + P+ + A + A T +
Sbjct: 963 PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
Query: 292 SALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEIT--PEPVSVVAA-VVDGA 348
A P G S PP PP P P LP AP P P A + GA
Sbjct: 1023 PAATPFPKGA---STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 349 VVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKR-------RKGFPT 389
+P+ P P AP+PP +PP + KG PT
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Score = 64.3 bits (155), Expect = 2e-10
Identities = 75/290 (25%), Positives = 109/290 (37%), Gaps = 41/290 (14%)
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE 180
GP + P G P +P P P+ P ++A + ++ G+++P
Sbjct: 1381 GPAMTPPSPKRGPAIP--SPKGDPTSPAVIPL---------SPKKAPATPVTREGAATPS 1429
Query: 181 ------PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLA 234
P P + PK + P S P LP A++PP P PP P
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT-LP--AVTPPSPKE--PPAPKQV 1484
Query: 235 QVAPSPPSPPPPPRP--PPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALS 292
+ SP P P P PTL A PS + + + R +A + LS
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPS---------SPKEVPATPSSRRDPIAPTATLLS 1535
Query: 293 ALLPLLPGTPVDSLPPP---LPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAV 349
P P ++L PP +P P P P P P P + P +V + GA
Sbjct: 1536 KKTPATL-APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA- 1593
Query: 350 VAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
+ + ++I P +P P AP PP +PP KG T +G SP
Sbjct: 1594 PSPKELLIPPAVT--SPSPKEAPTPPAVTPP-SPEKGPATPAPKGTPTSP 1640
Score = 57.8 bits (138), Expect = 2e-08
Identities = 82/311 (26%), Positives = 104/311 (33%), Gaps = 58/311 (18%)
Query: 124 VAAPGAGAGAEEPPAAPSSQPP----------PPSACPQRYVLSEDRREDRRADTSAHSK 173
V AP P P+ PP + P E ED A +A SK
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
Query: 174 AG----SSSPEPWA--------RPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALS-- 219
+ SP P RP G P S P S ++ LP +LS
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ 844
Query: 220 --PPPPAPPLPPPPPLAQVAPSPPSPPP--------PPRPPPTLSASDPSLDFLRAQQET 269
PA P PP + AP+P + P PP+ PT S +L F + T
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV--VNLPFPKEGPAT 902
Query: 270 ANAIRELAGTLRQGLAKLSEALSAL--LPLLPGTPVDSLPPPLPPPPP------PPP--- 318
+ A ++ K + A A +P P PP PP P P P
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 319 PPRPVLPPPAPK-VEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHD 377
P P PP+PK TP P GA +P+ P P AP PP
Sbjct: 963 PTPPAATPPSPKGGPATPSP--------KGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014
Query: 378 SPPHKRRKGFP 388
+PP KG P
Sbjct: 1015 TPPSP--KGSP 1023
Score = 52.4 bits (124), Expect = 7e-07
Identities = 74/289 (25%), Positives = 103/289 (35%), Gaps = 47/289 (16%)
Query: 134 EEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSC-TPQEG 192
+E PA PSS+ P P +LS+ + A A + P P P+ TP+E
Sbjct: 1514 KEVPATPSSRRDP--IAPTATLLSK-KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA 1570
Query: 193 -GCPRPKERESPP---PSALQPVQLPRLALSPPP---------PAPP--LPPPPPLAQVA 237
P KE SPP PS + P+ L PP P PP PP P
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 238 PSPP-SPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLP 296
P+P +P PP P +L S S + + ++G L E L A P
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA--P 1688
Query: 297 LLPGTPVDSLP--------------PPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVA 342
TP+ + P PP+ P P + L AP + + S
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748
Query: 343 AVVDGAVVAARGVIIAPRS-----------EEGAPRPPPAPLPPHDSPP 380
A A + +G + P S E+ P+P A + SPP
Sbjct: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797
Score = 44.3 bits (103), Expect = 2e-04
Identities = 74/312 (23%), Positives = 107/312 (34%), Gaps = 53/312 (16%)
Query: 87 TKEKLARVPHSTQGAGPAA--EDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQP 144
T ++ P S + + P A + ++ P V +P +E P P+ P
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP----KEAPTPPAVTP 1621
Query: 145 PPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPP 204
P P P + TS S P + S T + G + P
Sbjct: 1622 PSPEKGPATPA-------PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
Query: 205 ---PSALQPVQL-PRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPP-----RPPPTLSA 255
P+AL+ V + P +P AP P A SPP P P + P + A
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734
Query: 256 SDPSLDFLRAQQETA---NAIRELAGTLRQGLAKLSEALSA-----LLPLLPGTPVDSLP 307
P L + +TA +A G L +K S L+A +LP V + P
Sbjct: 1735 PAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP 1794
Query: 308 PP-----LPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSE 362
P L P P P PP+ P +P G V+ + +AP E
Sbjct: 1795 SPPVSLPLAPSPVPTLPPKQQFLPSSP-----------------GLVLESPSKPLAPADE 1837
Query: 363 -EGAPRPPPAPL 373
E P PP P+
Sbjct: 1838 DELLPLIPPEPI 1849
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/204 (27%), Positives = 70/204 (34%), Gaps = 25/204 (12%)
Query: 188 TPQEGGCPRPKERESPPPSALQ-PVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPP- 245
T QE P+ + P SAL L + + PPP P P PL+ + P P P
Sbjct: 12 TEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPS 71
Query: 246 -----PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPG 300
P P S+S +L L E + L G A L+ A + P L G
Sbjct: 72 TIASTPLEVPFPQSSSGTALP-LGTAPEAPTFLPNLIGP-PISPAALALASPMIAPTLKG 129
Query: 301 TPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPR 360
TP S P L P PP + P SV AV + V IAP
Sbjct: 130 TPSSSAPLALVALAPHSVQKSSAFPP-----NLLTSPPSV--AVAESGSVITLSAPIAPS 182
Query: 361 S---------EEGAPRPPPAPLPP 375
E P P P PP
Sbjct: 183 EPKTNLNKVPSEVVPNPKGTPSPP 206
Score = 40.8 bits (94), Expect = 0.002
Identities = 46/185 (24%), Positives = 69/185 (37%), Gaps = 24/185 (12%)
Query: 174 AGSSSPEPWARPSCTPQEGGCPRPKERE-----SPPPSALQPVQLP--------RLALSP 220
A P P P C+P CP + SP A P+++P L L
Sbjct: 36 AALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGT 95
Query: 221 PPPAPPLPP---PPPLAQVAPSPPSPPPPPRPPPTLSASDP----SLDFLRAQQETANAI 273
P AP P PP++ A + SP P T S+S P +L Q+ +A
Sbjct: 96 APEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP 155
Query: 274 RELAGTLRQGLAKLSEALSALLPLLPGTP---VDSLPPPLPPPPPPPPPPRPVLPPPAPK 330
L +A+ ++ P+ P P ++ +P + P P P P P + P
Sbjct: 156 NLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP-PCIVSTVPY 214
Query: 331 VEITP 335
+TP
Sbjct: 215 HCVTP 219
Score = 37.0 bits (84), Expect = 0.031
Identities = 74/333 (22%), Positives = 114/333 (34%), Gaps = 70/333 (21%)
Query: 94 VPHSTQGAGPAAEDAFSAEEETIFA-ILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQ 152
VP +G A + E T ++GP ++ A P AP+ + P S+ P
Sbjct: 80 VPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP--AALALASPMIAPTLKGTPSSSAPL 137
Query: 153 RYVLSEDRREDRRA----------DTSAHSKAGS----SSP----EPWARPSCTPQEGGC 194
V + + + A +++GS S+P EP + P E
Sbjct: 138 ALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEV-V 196
Query: 195 PRPKERESPP----------PSALQPVQLPRLALSPPPPAPPLPPPPP------LAQVAP 238
P PK SPP + + +Q +L P L P ++ V
Sbjct: 197 PNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLI 256
Query: 239 SPPSPPP-----PPRPPPTLSASDPSLDFLRAQQETA--NAIRELAGTLRQGLAKLSEAL 291
SP +P P PP LS S SL + + Q+TA N + +L LA L ++
Sbjct: 257 SPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSS 316
Query: 292 SALLPLLPGTPVDSLP-------------------------PPLPPPPPPPPPPRPVLPP 326
+ LL T +L PPLP P P
Sbjct: 317 FGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPV 376
Query: 327 PAPKVEITPEPVSVVAAVVDGAVVAARGVIIAP 359
AP V+ P +S + G++ A ++P
Sbjct: 377 VAPSVDKGPSTISSITCSPSGSLNVATSFSLSP 409
Score = 29.6 bits (65), Expect = 5.0
Identities = 18/63 (28%), Positives = 26/63 (41%), Gaps = 1/63 (1%)
Query: 183 ARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPS 242
A P+ T + C P S P S ++P L ++P P P ++ SPP
Sbjct: 451 AAPTTTFEVATCVSPP-MSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPL 509
Query: 243 PPP 245
P P
Sbjct: 510 PDP 512
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 73.6 bits (179), Expect = 3e-13
Identities = 67/231 (29%), Positives = 89/231 (38%), Gaps = 38/231 (16%)
Query: 167 DTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPP 226
+T K S P S P + PRP R S + QP PP PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAK---PRPFFRSSSLDISAQP-----------PPPPP 2410
Query: 227 LPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAK 286
PPPPP P PP PPPPP PPPT P L ++ T + A L +
Sbjct: 2411 PPPPPP-----PPPPPPPPPPLPPPT----SPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 287 LSEALSALLPLLPGTPV-DSLPPPLPPPPPPPPP-------PRPVLPPPAPKVEI----- 333
L LP T + + PPP+PP P P P P PP APK I
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPT 2521
Query: 334 -TPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKR 383
T +P + ++ ++ + + ++ P P +PL PH + R
Sbjct: 2522 TTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLP-SPTSPLSPHSNKSSPR 2571
Score = 52.4 bits (124), Expect = 7e-07
Identities = 68/286 (23%), Positives = 93/286 (32%), Gaps = 34/286 (11%)
Query: 133 AEEPPAAPSSQPPP-------PSACPQ----RYVLSED--RREDRRADTSAHSKAGSSSP 179
+ + P SQPP P+ PQ + L D R + ++AD S P
Sbjct: 240 SSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP 299
Query: 180 EPWARPSCTPQEGGCP--RPKERESPPPSALQPVQ----LPRLALSPPPPAPPLPPPPPL 233
P P P G P +P +S P A P Q LA P PP+ PP
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG-- 357
Query: 234 AQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSA 293
PP+ P P PP A + ++Q A+ + G + +
Sbjct: 358 ---TTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG----- 406
Query: 294 LLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR 353
P P T P PL P P + P P + P + A
Sbjct: 407 --PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464
Query: 354 GVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
G P G +PPP P PP + P ++ G K P
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Score = 51.2 bits (121), Expect = 2e-06
Identities = 73/317 (23%), Positives = 107/317 (33%), Gaps = 34/317 (10%)
Query: 92 ARVPHSTQGAGPAAEDAFSAEEETIFAILG----PGVAAPGAGAGAEEPPAAPSSQPPPP 147
A++P + P + A E++ L P + P G + P SQP P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 148 SACPQRYVLSEDRREDRRADTSAHSKAGSSSP--EPWARPSCTPQEGGCPRPKERESPPP 205
Q L++ + G++ P +P Q+ G +P + P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 206 SALQPVQLPRLALSPPPPAPP----LPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLD 261
+ QP + + P PA P + P PLAQ P SP P P T P
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ-QPGLQSPAKAPGPTKT-PVQQPGPG 447
Query: 262 FLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPP----PPPP- 316
+ AQQ + G K L P P + PPP P PP
Sbjct: 448 KIPAQQAGPGK----TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 317 -----PPPPRPVLPPPAPKVEITPEPVS------VVAAVVDGAVVAARGVIIAPRSEEGA 365
PPP +P P+P+ + +P S +A + P S+ G+
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563
Query: 366 PRP--PPAPLPPHDSPP 380
+P PP P PP
Sbjct: 564 GKPLQPPTVSPSAKQPP 580
Score = 45.4 bits (106), Expect = 9e-05
Identities = 54/236 (22%), Positives = 79/236 (33%), Gaps = 18/236 (7%)
Query: 99 QGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAA--PSSQPPPPSACPQRYVL 156
Q GPA A E P PG A A+ P P+ QP P Q+
Sbjct: 364 QPLGPAKPPAQQTGSEK------PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417
Query: 157 SEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRL 216
+ + + A + + +P P P + P + P+ P QLP
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK-PPSQLPGP 476
Query: 217 ALSPPPPAPPLPPPP--PLAQVAPS--PPSPPPPPRPPPTLSASDPSLDFLRAQQETANA 272
A PP P PPP P + PS P S PPP+ P S + + +
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 273 IRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPP---PRPVLP 325
+ A ++ + G P+ PP + P PP P+ + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ--PPTVSPSAKQPPSQGLPKTICP 590
Score = 44.3 bits (103), Expect = 2e-04
Identities = 62/268 (23%), Positives = 90/268 (33%), Gaps = 32/268 (11%)
Query: 129 AGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCT 188
+ + A P PSS+ + L D + ++ K + RP+
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 189 PQEGGCPRPKERESPPPSALQPVQL---PRLA---LSPPPPAPPLP--------PPPPLA 234
+ P P ES + PVQ P+ A +SP P A P+P P P
Sbjct: 828 SKIISHPGPSS-ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAG 886
Query: 235 QVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSAL 294
Q P+P P P S + S+ Q T + G L A + S L
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ-ETVTGKLFGFGASIFSQASNL 945
Query: 295 LPLL----------PGTPVDSLPPPLPPPPPPPPPPRPVLPPPAP--KVEITPEPVSVVA 342
+ PG P+ P P PP PP PPAP + + E + A
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005
Query: 343 AVVDGAVVAARGVIIAPRSEEGAPRPPP 370
++ A V + E +PPP
Sbjct: 1006 EKLEPKAEQAPTV----KRTETEKKPPP 1029
Score = 43.5 bits (101), Expect = 3e-04
Identities = 71/304 (23%), Positives = 105/304 (34%), Gaps = 44/304 (14%)
Query: 95 PHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRY 154
P S +G + + A+ F ++A PP P PPPP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP-- 2429
Query: 155 VLSEDRREDRRADTSAHSKAGSSSPEPWARP----------SCTPQEGGCPRPKE-RESP 203
+ K +SP A P + + G P + +P
Sbjct: 2430 ------PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 204 PPSALQPVQLPR---LALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPT---LSASD 257
PP +P +P P P PP+ P P + Q+ P+ P P PT L++S
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLSLTSSM 2542
Query: 258 PSLDFLRAQQETANAIRELAGTLRQGLAKLSEALS-----ALLPLLPGTPVDSLPP---- 308
A + + L+ + + S++L+ LP PGTP DS
Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAIT 2602
Query: 309 --PLPPPPPPPPPPRPV--LPPPAPKVEITPEPVSVVAA-VVDGAVVAARGV-IIAPRSE 362
PL P PV + PP VEI P+S + GA+ + AP S
Sbjct: 2603 SWPLGSPSKDLVSVEPVFSVVPPVTAVEI---PISSEQTFYISGALQTFSATPVTAPSSF 2659
Query: 363 EGAP 366
+ AP
Sbjct: 2660 QAAP 2663
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/196 (25%), Positives = 70/196 (35%), Gaps = 33/196 (16%)
Query: 188 TPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQ-----------V 236
TP+ +P++ +S PP +P+Q P PL Q V
Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 237 APSPPSPPPPPRPPPTLS---ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSA 293
PS PSP PP PT A P + ++Q A + +G L+
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHE--KSQPGPAKPPAQPSG------------LTK 340
Query: 294 LLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR 353
L PGT + PP+ PP PP +P L P P + T A+
Sbjct: 341 PLAQQPGT----VKPPVQPPGTTKPPAQP-LGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 354 GVIIAPRSEEGAPRPP 369
GV P + G +PP
Sbjct: 396 GVGKTPAQQPGPAKPP 411
Score = 39.3 bits (90), Expect = 0.006
Identities = 40/178 (22%), Positives = 63/178 (35%), Gaps = 9/178 (5%)
Query: 164 RRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQP-VQLPRLALSPPP 222
+ A + S SSP+P +P++ P+ ++P P P V+ P L SP
Sbjct: 662 KTAPVTTTSAVSKSSPQP---QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 223 PAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQ 282
A P L++ P+PP P P +D + + T + + + T +
Sbjct: 719 KAKQPPEADSLSK--PAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 283 GLAKLSEALSALLPLLPGTPVDSLPPPLPPPP---PPPPPPRPVLPPPAPKVEITPEP 337
+ A P DS P PP P +P PA +I P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Score = 31.2 bits (69), Expect = 1.7
Identities = 39/165 (23%), Positives = 57/165 (34%), Gaps = 12/165 (7%)
Query: 216 LALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRE 275
LA P P P L P A S SP P P +A P D +A + ++
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA--PKQDLSKAPEP-----KK 702
Query: 276 LAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITP 335
++Q S + A P DSL P PP P P + P K + P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQP----PEADSLSKPAPPKEPSVPSEQDKAPVADDKPK-QP 757
Query: 336 EPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
+ V +V + + I + + + A PL + P
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKP 802
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 73.6 bits (179), Expect = 3e-13
Identities = 67/231 (29%), Positives = 89/231 (38%), Gaps = 38/231 (16%)
Query: 167 DTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPP 226
+T K S P S P + PRP R S + QP PP PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAK---PRPFFRSSSLDISAQP-----------PPPPP 2410
Query: 227 LPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAK 286
PPPPP P PP PPPPP PPPT P L ++ T + A L +
Sbjct: 2411 PPPPPP-----PPPPPPPPPPLPPPT----SPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 287 LSEALSALLPLLPGTPV-DSLPPPLPPPPPPPPP-------PRPVLPPPAPKVEI----- 333
L LP T + + PPP+PP P P P P PP APK I
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPT 2521
Query: 334 -TPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKR 383
T +P + ++ ++ + + ++ P P +PL PH + R
Sbjct: 2522 TTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLP-SPTSPLSPHSNKSSPR 2571
Score = 52.4 bits (124), Expect = 7e-07
Identities = 68/286 (23%), Positives = 93/286 (32%), Gaps = 34/286 (11%)
Query: 133 AEEPPAAPSSQPPP-------PSACPQ----RYVLSED--RREDRRADTSAHSKAGSSSP 179
+ + P SQPP P+ PQ + L D R + ++AD S P
Sbjct: 240 SSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP 299
Query: 180 EPWARPSCTPQEGGCP--RPKERESPPPSALQPVQ----LPRLALSPPPPAPPLPPPPPL 233
P P P G P +P +S P A P Q LA P PP+ PP
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG-- 357
Query: 234 AQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSA 293
PP+ P P PP A + ++Q A+ + G + +
Sbjct: 358 ---TTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG----- 406
Query: 294 LLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR 353
P P T P PL P P + P P + P + A
Sbjct: 407 --PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464
Query: 354 GVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
G P G +PPP P PP + P ++ G K P
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Score = 51.2 bits (121), Expect = 2e-06
Identities = 73/317 (23%), Positives = 107/317 (33%), Gaps = 34/317 (10%)
Query: 92 ARVPHSTQGAGPAAEDAFSAEEETIFAILG----PGVAAPGAGAGAEEPPAAPSSQPPPP 147
A++P + P + A E++ L P + P G + P SQP P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 148 SACPQRYVLSEDRREDRRADTSAHSKAGSSSP--EPWARPSCTPQEGGCPRPKERESPPP 205
Q L++ + G++ P +P Q+ G +P + P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 206 SALQPVQLPRLALSPPPPAPP----LPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLD 261
+ QP + + P PA P + P PLAQ P SP P P T P
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ-QPGLQSPAKAPGPTKT-PVQQPGPG 447
Query: 262 FLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPP----PPPP- 316
+ AQQ + G K L P P + PPP P PP
Sbjct: 448 KIPAQQAGPGK----TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 317 -----PPPPRPVLPPPAPKVEITPEPVS------VVAAVVDGAVVAARGVIIAPRSEEGA 365
PPP +P P+P+ + +P S +A + P S+ G+
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563
Query: 366 PRP--PPAPLPPHDSPP 380
+P PP P PP
Sbjct: 564 GKPLQPPTVSPSAKQPP 580
Score = 45.4 bits (106), Expect = 9e-05
Identities = 54/236 (22%), Positives = 79/236 (33%), Gaps = 18/236 (7%)
Query: 99 QGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAA--PSSQPPPPSACPQRYVL 156
Q GPA A E P PG A A+ P P+ QP P Q+
Sbjct: 364 QPLGPAKPPAQQTGSEK------PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417
Query: 157 SEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRL 216
+ + + A + + +P P P + P + P+ P QLP
Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK-PPSQLPGP 476
Query: 217 ALSPPPPAPPLPPPP--PLAQVAPS--PPSPPPPPRPPPTLSASDPSLDFLRAQQETANA 272
A PP P PPP P + PS P S PPP+ P S + + +
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 273 IRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPP---PRPVLP 325
+ A ++ + G P+ PP + P PP P+ + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ--PPTVSPSAKQPPSQGLPKTICP 590
Score = 44.3 bits (103), Expect = 2e-04
Identities = 62/268 (23%), Positives = 90/268 (33%), Gaps = 32/268 (11%)
Query: 129 AGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCT 188
+ + A P PSS+ + L D + ++ K + RP+
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 189 PQEGGCPRPKERESPPPSALQPVQL---PRLA---LSPPPPAPPLP--------PPPPLA 234
+ P P ES + PVQ P+ A +SP P A P+P P P
Sbjct: 828 SKIISHPGPSS-ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAG 886
Query: 235 QVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSAL 294
Q P+P P P S + S+ Q T + G L A + S L
Sbjct: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ-ETVTGKLFGFGASIFSQASNL 945
Query: 295 LPLL----------PGTPVDSLPPPLPPPPPPPPPPRPVLPPPAP--KVEITPEPVSVVA 342
+ PG P+ P P PP PP PPAP + + E + A
Sbjct: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005
Query: 343 AVVDGAVVAARGVIIAPRSEEGAPRPPP 370
++ A V + E +PPP
Sbjct: 1006 EKLEPKAEQAPTV----KRTETEKKPPP 1029
Score = 43.5 bits (101), Expect = 3e-04
Identities = 71/304 (23%), Positives = 105/304 (34%), Gaps = 44/304 (14%)
Query: 95 PHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRY 154
P S +G + + A+ F ++A PP P PPPP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP-- 2429
Query: 155 VLSEDRREDRRADTSAHSKAGSSSPEPWARP----------SCTPQEGGCPRPKE-RESP 203
+ K +SP A P + + G P + +P
Sbjct: 2430 ------PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 204 PPSALQPVQLPR---LALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPT---LSASD 257
PP +P +P P P PP+ P P + Q+ P+ P P PT L++S
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLSLTSSM 2542
Query: 258 PSLDFLRAQQETANAIRELAGTLRQGLAKLSEALS-----ALLPLLPGTPVDSLPP---- 308
A + + L+ + + S++L+ LP PGTP DS
Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAIT 2602
Query: 309 --PLPPPPPPPPPPRPV--LPPPAPKVEITPEPVSVVAA-VVDGAVVAARGV-IIAPRSE 362
PL P PV + PP VEI P+S + GA+ + AP S
Sbjct: 2603 SWPLGSPSKDLVSVEPVFSVVPPVTAVEI---PISSEQTFYISGALQTFSATPVTAPSSF 2659
Query: 363 EGAP 366
+ AP
Sbjct: 2660 QAAP 2663
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/196 (25%), Positives = 70/196 (35%), Gaps = 33/196 (16%)
Query: 188 TPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQ-----------V 236
TP+ +P++ +S PP +P+Q P PL Q V
Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 237 APSPPSPPPPPRPPPTLS---ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSA 293
PS PSP PP PT A P + ++Q A + +G L+
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHE--KSQPGPAKPPAQPSG------------LTK 340
Query: 294 LLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR 353
L PGT + PP+ PP PP +P L P P + T A+
Sbjct: 341 PLAQQPGT----VKPPVQPPGTTKPPAQP-LGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 354 GVIIAPRSEEGAPRPP 369
GV P + G +PP
Sbjct: 396 GVGKTPAQQPGPAKPP 411
Score = 39.3 bits (90), Expect = 0.006
Identities = 40/178 (22%), Positives = 63/178 (35%), Gaps = 9/178 (5%)
Query: 164 RRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQP-VQLPRLALSPPP 222
+ A + S SSP+P +P++ P+ ++P P P V+ P L SP
Sbjct: 662 KTAPVTTTSAVSKSSPQP---QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 223 PAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQ 282
A P L++ P+PP P P +D + + T + + + T +
Sbjct: 719 KAKQPPEADSLSK--PAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 283 GLAKLSEALSALLPLLPGTPVDSLPPPLPPPP---PPPPPPRPVLPPPAPKVEITPEP 337
+ A P DS P PP P +P PA +I P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP 834
Score = 31.2 bits (69), Expect = 1.7
Identities = 39/165 (23%), Positives = 57/165 (34%), Gaps = 12/165 (7%)
Query: 216 LALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRE 275
LA P P P L P A S SP P P +A P D +A + ++
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA--PKQDLSKAPEP-----KK 702
Query: 276 LAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITP 335
++Q S + A P DSL P PP P P + P K + P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQP----PEADSLSKPAPPKEPSVPSEQDKAPVADDKPK-QP 757
Query: 336 EPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
+ V +V + + I + + + A PL + P
Sbjct: 758 KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKP 802
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 73.6 bits (179), Expect = 3e-13
Identities = 60/206 (29%), Positives = 69/206 (33%), Gaps = 53/206 (25%)
Query: 130 GAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWA-----R 184
G G PP P P Q ++ D DR + + SS E
Sbjct: 589 GLGPRPPPEP--GPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEM 646
Query: 185 PSCTPQEGGCPRPKERESPPPSALQP-VQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSP 243
PS CP+P + P V P L L PPP PPLPPPPP P P P
Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMP 706
Query: 244 PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPV 303
PP P PPP P P P
Sbjct: 707 PPLPPPPP--------------------------------------------PPPPAHPA 722
Query: 304 DSLPPPLPPPPPPPPPPRPVLPPPAP 329
++PPP P P PP PP P+LPP P
Sbjct: 723 VTVPPP-PLPAPPGVPPPPILPPLPP 747
Score = 66.6 bits (161), Expect = 4e-11
Identities = 78/276 (28%), Positives = 98/276 (35%), Gaps = 64/276 (23%)
Query: 95 PHSTQGAGPAAEDAFSAEEETIFAILG--PGVAAPGAGAGAEEP--PAAPSSQPPPPSAC 150
PH+ G A+ S ET+ A G P ++ +G P P +P S P P +
Sbjct: 1318 PHTPGLCGSLAK---SQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
Query: 151 PQRYVLSEDRREDRRADTSAHSKAG---SSSPEPWAR------PSCTPQ--EGGCPRPKE 199
+ R+ T + P P R P +P E G P P
Sbjct: 1375 SSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLP 1434
Query: 200 RESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPS 259
P P AL V R P P PPL P P + P P P R PP++ + D
Sbjct: 1435 LPLPLPLALPAVL--RAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP 1492
Query: 260 LDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTP----------------- 302
L +R AG AL L LLPG P
Sbjct: 1493 L------------VRPPAGA----------ALGRELLLLPGQPQTPVFPSTHDPRTVTLD 1530
Query: 303 -----VDSLPPPLPPPPPPPPPPRPVLPPPAPKVEI 333
+ + PPPLPP PPPPPPP PV P P E+
Sbjct: 1531 FRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKEL 1566
Score = 65.9 bits (159), Expect = 6e-11
Identities = 67/221 (30%), Positives = 82/221 (37%), Gaps = 31/221 (14%)
Query: 166 ADTSAHSKAGSSSPEP-WARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPA 224
A +S+ G P P +RPS T E P +P P + + +L L L P PP
Sbjct: 544 APFGTNSQPGFRGPTPPSSRPSSTGLEDISP------TPLPDSDEDEELD-LGLGPRPPP 596
Query: 225 PPLPPPPP-----LAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAG- 278
P PP P A+VA P D + E +A A
Sbjct: 597 EPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADC 656
Query: 279 ----TLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEIT 334
+ G A ++ A S L P LP P PP PPPPPPPP P +PPP P
Sbjct: 657 PKPMVVTPGAAAVA-APSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPP 715
Query: 335 PEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPP 375
P P V + A GV PPP LPP
Sbjct: 716 PPPAHPAVTVPPPPLPAPPGV------------PPPPILPP 744
Score = 59.7 bits (143), Expect = 5e-09
Identities = 94/359 (26%), Positives = 125/359 (34%), Gaps = 52/359 (14%)
Query: 74 QEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAG--A 131
+EV R + + +E +A S AGP ED EE A P V + G
Sbjct: 1136 EEVVAREEEEEEEEEEMVAE--ESMASAGP--EDFEQDGEEAALAPGAPAVDSLGMEEEV 1191
Query: 132 GAEEPPAAPSSQPPPPSACPQRYVLSE--DRREDRRADTSAHSKAGSSSPEP-----WAR 184
E AP +P P + E D RE + A SPEP AR
Sbjct: 1192 DIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEAR 1251
Query: 185 PSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPS-PPSP 243
P +P+ + PP P+Q P PP P P P P PS PP P
Sbjct: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311
Query: 244 PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPV 303
PP T P L A+ ++ + G L+ S LS P +PG+P
Sbjct: 1312 LAEDHPPHT-----PGLCGSLAKSQSTETVPATPGG-EPPLSGGSSGLSLSSPQVPGSPF 1365
Query: 304 DSLPPP--------LPPPP------------PPPPPPRPVLPPPAPKVEITPEPVSVVAA 343
S P P LP P P P PV P P + + P++
Sbjct: 1366 -SYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVL 1424
Query: 344 VVDG---------AVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRR 393
+ G + A ++ ++ P PP P P PP +RK P R RR
Sbjct: 1425 LETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRK--PGRPRR 1481
Score = 56.6 bits (135), Expect = 4e-08
Identities = 62/254 (24%), Positives = 90/254 (35%), Gaps = 50/254 (19%)
Query: 106 EDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRR 165
++ S EEET+ + A + + + S P S + V E+ E+
Sbjct: 1090 DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEE 1149
Query: 166 ADTSAHSKAGSSSPEPWARPSCTPQEG-GCPRP-----KERESPPPSALQPVQLPRLALS 219
+ A S+ PE + + G P +E A+ P + P +
Sbjct: 1150 EEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDE 1209
Query: 220 PP------PPAPPLPPP--PPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETAN 271
PP PA PP P L+Q SP PP + + P L RA +
Sbjct: 1210 PPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVE----ARPPLSPERAPEHD-- 1263
Query: 272 AIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKV 331
L + P P+ LP PL PP PPP PPRP PPP P+
Sbjct: 1264 -----------------------LEVEPEPPM-MLPLPLQPPLPPPRPPRPPSPPPEPET 1299
Query: 332 ------EITPEPVS 339
+ PEP++
Sbjct: 1300 TDASHPSVPPEPLA 1313
Score = 55.1 bits (131), Expect = 1e-07
Identities = 81/340 (23%), Positives = 106/340 (31%), Gaps = 97/340 (28%)
Query: 103 PAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQ-----RYVLS 157
P A AF A + F P A A+E P P PPP + + + S
Sbjct: 414 PTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWS 473
Query: 158 EDRREDRRADTSAHSKAGSSSPEPW--ARPSCTPQEGGCPRPKERESPPPSALQ----PV 211
+ + T S AG P +R +E RE + LQ P+
Sbjct: 474 PEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPI 533
Query: 212 QLPRLALSP--------------PPPAPPLPPPPPLAQVAPSP---------------PS 242
LSP P P P L ++P+P P
Sbjct: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPR 593
Query: 243 PPPPPRPPPTLS----ASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLL 298
PPP P PP ++ +LD + + T+ + E +Q + E +P
Sbjct: 594 PPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEG----QQSSGEDMEISDDEMPSA 649
Query: 299 PGTPVDS------------------LPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSV 340
P T D L P LP PPPP PP P PPP P P+P
Sbjct: 650 PITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPP-----PQP--- 701
Query: 341 VAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPP 380
G P PPP P PP PP
Sbjct: 702 -----------------------GFPMPPPLPPPPPPPPP 718
Score = 54.7 bits (130), Expect = 1e-07
Identities = 70/260 (26%), Positives = 85/260 (32%), Gaps = 79/260 (30%)
Query: 175 GSSSPEPWARPSCTPQEGGCPRPKERESPP--PSALQPVQLPRLALSPPP---------- 222
GSS P A+P + P P + P SA P Q P PPP
Sbjct: 362 GSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFG 421
Query: 223 ----------PAPP-LPPPPPLAQVAPSPPSPPPPP---------------RPPPTLSAS 256
PAPP LPP PLA+ P P PPPP P P S
Sbjct: 422 ARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPG 481
Query: 257 DPSLDFLRAQQETA-----NAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLP 311
P+L+ A E + I L R L L E S + G+P+ S L
Sbjct: 482 TPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLS 541
Query: 312 PPPPPPPPPRPVLPPPAPK---------VEITPEPVSVVAAVVDGAVVAARGVIIAPRSE 362
P P +P P P +I+P P+ P S+
Sbjct: 542 PLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPL--------------------PDSD 581
Query: 363 EG-------APRPPPAPLPP 375
E PRPPP P PP
Sbjct: 582 EDEELDLGLGPRPPPEPGPP 601
Score = 51.2 bits (121), Expect = 2e-06
Identities = 68/247 (27%), Positives = 90/247 (36%), Gaps = 54/247 (21%)
Query: 134 EEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGG 193
+E P+AP + + CP+ V++ A +A S + P P P G
Sbjct: 644 DEMPSAPITS----ADCPKPMVVTPGA-----AAVAAPSVLAPTLPLP-------PPPGF 687
Query: 194 CPRPKERESPPPSALQPVQLPRLALSPPPPAPP-----LPPPPPLAQVAPSPPSPPPPPR 248
P P PPP P+ P PPPP PP PPPPL P+PP PPPP
Sbjct: 688 PPLPPPPPPPPPQPGFPMPPP--LPPPPPPPPPAHPAVTVPPPPL----PAPPGVPPPPI 741
Query: 249 PPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALL------PLLP--- 299
PP L P L F Q + ++ + G + ++ LS L+ P P
Sbjct: 742 LPP-LPPFPPGL-FPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMA 799
Query: 300 --------GTPVDSLPP---PLPPPPPPPP-----PPRPVLPPPAPKVEITPEPVSVVAA 343
G +LPP P P PP P P P P A
Sbjct: 800 AAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKA 859
Query: 344 VVDGAVV 350
VDG ++
Sbjct: 860 TVDGVLL 866
Score = 30.8 bits (68), Expect = 2.3
Identities = 36/133 (27%), Positives = 42/133 (31%), Gaps = 43/133 (32%)
Query: 190 QEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRP 249
+ G P P PPP QP PPPP P P P ++ PS PP P
Sbjct: 1532 RNAGIPAP-----PPPLPPQPPP-------PPPPPPVEPTKLPFKELDNQWPSEAIPPGP 1579
Query: 250 PPTLSASDPSLDFLRAQQETANAIRELA---GTLRQGLAKLSEALSALLPLLPGTPVDSL 306
R + E ELA G R+ K E D +
Sbjct: 1580 --------------RGRDEVTEEYMELAKSRGPWRRPPKKRHE--------------DLV 1611
Query: 307 PPPLPPPPPPPPP 319
PP P PP P
Sbjct: 1612 PPAGSPELSPPQP 1624
Score = 29.6 bits (65), Expect = 5.0
Identities = 29/117 (24%), Positives = 38/117 (32%), Gaps = 37/117 (31%)
Query: 129 AGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDR------------RADTSAHSKAGS 176
AG A PP P PPPP + L +++ R + + +
Sbjct: 1534 AGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELA 1593
Query: 177 SSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPL 233
S PW RP PK+R L PP +P L PP PL
Sbjct: 1594 KSRGPWRRP-----------PKKRHED--------------LVPPAGSPELSPPQPL 1625
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 73.6 bits (179), Expect = 3e-13
Identities = 74/265 (27%), Positives = 96/265 (36%), Gaps = 75/265 (28%)
Query: 91 LARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSAC 150
L R+P + G GP + PGV+ P A EEP P
Sbjct: 1445 LHRLPPTAPGVGPLLLQLGTEPPAP-----HPGVSKPWRSAAPEEPERLP---------- 1489
Query: 151 PQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQP 210
+V + + R TS P G P P R S PPS P
Sbjct: 1490 --LHVRFLENCQPRAPVTSGRGPPSEDGP-------------GVPPPSPRRSVPPSPTSP 1534
Query: 211 VQ-----LPRLALSPPPPA-----------PPLPPP--------PPLAQVAPSPPSP--- 243
LP L L PP P+ PLPPP P + + P PP P
Sbjct: 1535 RASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPD 1594
Query: 244 ------PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALL-- 295
P PP PPP ++A+ P+LD TA+++ + +A L++ SA
Sbjct: 1595 TPAPATPLPPVPPPAVAAAPPTLD------STASSLT----SYDSEVATLTQGASAAPGD 1644
Query: 296 PLLPGTPVDSLPPPLPPPPPPPPPP 320
P PG P + P P P P P PPP
Sbjct: 1645 PHPPGPPAPAAPAPAAPQPGPDPPP 1669
Score = 63.5 bits (153), Expect = 3e-10
Identities = 94/390 (24%), Positives = 123/390 (31%), Gaps = 106/390 (27%)
Query: 69 WKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPG 128
W+ E +R R + R P T G GP +ED GPGV P
Sbjct: 1477 WRSAAPEEPERLPLHVRFLENCQPRAP-VTSGRGPPSED-------------GPGVPPPS 1522
Query: 129 AGAGAEEPPAAPSSQ-----------PPPPSACPQ--RYVLSEDRREDRRADTSAHSKAG 175
P +P + PP PS + ++ E S
Sbjct: 1523 PRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPES 1582
Query: 176 SSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPP------------- 222
+P P P P P + L PV P +A +PP
Sbjct: 1583 PLTPGP-------------PHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDS 1629
Query: 223 ------------PAPPLPPPPPLAQVAPSPPSPPPPPRPPP----------TLSASDPSL 260
P P PP PP A AP+P +P P P PPP + S+SD L
Sbjct: 1630 EVATLTQGASAAPGDPHPPGPP-APAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPL 1688
Query: 261 DFLRAQQETANAIRELAGT------LRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPP 314
+ + + ++ E G+ G+A E L + L G P PP P
Sbjct: 1689 ETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYP 1748
Query: 315 PPPPPPRP-----------VLPPPA----PKVEITPEPVSVVAAVVDGAVV-------AA 352
P P + P P+ V T VSV A DG +
Sbjct: 1749 PQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPT 1808
Query: 353 RGVIIAPRSEEGAPRPPPAPLPPHDSPPHK 382
GV P + E P PP PLP S P K
Sbjct: 1809 AGVAGGPVAVE--PEVPPVPLPTASSLPRK 1836
Score = 55.5 bits (132), Expect = 9e-08
Identities = 83/316 (26%), Positives = 101/316 (31%), Gaps = 81/316 (25%)
Query: 130 GAGAEEPPAAPSS---QPPPPSA---CPQRY---VL--------SEDRRE-DRRADTSAH 171
G GA +PP P S + PPP+ P + VL RRE RA +
Sbjct: 1370 GGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQ 1429
Query: 172 SKAGSSSPEPWAR-------PSCTPQEGGC--------PRPKERESPPPSALQPVQLPRL 216
K+ +SP P AR P P G P P S P + P + RL
Sbjct: 1430 EKSLPASP-PAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERL 1488
Query: 217 ALS-------------------PPPPAPPLPPPPPLAQVAPSPPSP--------PPPPRP 249
L P P +PPP P V PSP SP P P
Sbjct: 1489 PLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLP 1548
Query: 250 PPTLSASDPSLDFLRAQQ-----ETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVD 304
PP S +FL + E +N+ + L G P P+
Sbjct: 1549 PPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPG---------------PPHPLP 1593
Query: 305 SLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEG 364
P P P PP PPP PP + A + AA G P
Sbjct: 1594 DTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAP 1653
Query: 365 APRPPPAPLPPHDSPP 380
A P AP P D PP
Sbjct: 1654 AAPAPAAPQPGPDPPP 1669
Score = 51.6 bits (122), Expect = 1e-06
Identities = 84/340 (24%), Positives = 112/340 (32%), Gaps = 103/340 (30%)
Query: 113 EETIFAILGPGVAAPGAGAGAEE-------PPA--------APSSQ--PPPPSACPQRYV 155
E F GPG+ GA E PPA P S+ PPPP+ P
Sbjct: 873 ERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPP--- 929
Query: 156 LSEDRREDRRADTSAHSKAGSSSPEPWARP----SCTPQEGGCPRPKERESPPPSALQPV 211
E + S +G +P P P S P P + SPP + +
Sbjct: 930 ------EPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSR 983
Query: 212 QLPRLALSPPPPA---PP------LPPPPPLAQVAPSPPSPP----------PPPR---- 248
+ P PPA PP PPP P A PP PP PPPR
Sbjct: 984 EKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHA-HPPHPPEMETGGSPDDPPPRLALG 1042
Query: 249 PPPTL----------------------------SASDPSLDFLRAQQETANA---IRELA 277
P P+L S+ P+L + + A+A + +
Sbjct: 1043 PQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARS 1102
Query: 278 GTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEP 337
G R+G PL+ T V+ P PP P P P P P P V E
Sbjct: 1103 GRGRKG------------PLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEK 1150
Query: 338 VSVVAAVVDGAVVAARGVIIAPRSEEGA---PRPPPAPLP 374
S+ + ++ A + RS +G+ PP P P
Sbjct: 1151 NSIPIPTI---IIKAPSTSSSGRSSQGSSTEAEPPTQPEP 1187
Score = 49.7 bits (117), Expect = 5e-06
Identities = 61/233 (26%), Positives = 79/233 (33%), Gaps = 58/233 (24%)
Query: 122 PGVAAP------GAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAG 175
PG +P G G G+ + PA Q PP +A YV + R R+ +K
Sbjct: 1059 PGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGR-GRKGPLVKQTKVE 1117
Query: 176 SSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQ 235
PQ+GG PP+ P P P P PP A
Sbjct: 1118 GE-----------PQKGG--------GLPPA--------------PSPTSPASPQPPPAV 1144
Query: 236 VAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALL 295
APS + P P T+ PS +G QG + +E +
Sbjct: 1145 AAPSEKNSIPIP----TIIIKAPSTSS--------------SGRSSQGSSTEAEPPTQPE 1186
Query: 296 PLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGA 348
P G S P P P P PP P PV P +P T + S A + GA
Sbjct: 1187 PTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGA 1239
Score = 46.6 bits (109), Expect = 4e-05
Identities = 55/185 (29%), Positives = 73/185 (39%), Gaps = 34/185 (18%)
Query: 224 APPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQG 283
AP PP PP +P +PPP P + +P L A A REL R G
Sbjct: 1373 APQPPPRPP----SPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDP-ARRELG--YRAG 1425
Query: 284 LAKLSEALSALLPLLPGTPVDSLPPPLPPPPP-------PPPPPRPVLPPP----APKVE 332
L ++L A P + + LPP P P PP P P + P AP+
Sbjct: 1426 LGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPE-- 1483
Query: 333 ITPEPVSVVAAVVDGA-----VVAARGVIIAPRSEEGAPRPPPAP---LPPH-DSPPHKR 383
PE + + ++ V + RG P SE+G PPP+P +PP SP
Sbjct: 1484 -EPERLPLHVRFLENCQPRAPVTSGRG----PPSEDGPGVPPPSPRRSVPPSPTSPRASE 1538
Query: 384 RKGFP 388
G P
Sbjct: 1539 ENGLP 1543
Score = 41.2 bits (95), Expect = 0.002
Identities = 49/172 (28%), Positives = 63/172 (36%), Gaps = 33/172 (19%)
Query: 237 APSPPSPPPPPR---PPPTLSASDPSLDF-----LRAQQETANAIRELAGTLRQGLAKLS 288
AP PP PP PR PPPT P L A REL R GL
Sbjct: 1373 APQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELG--YRAGLGSQE 1430
Query: 289 EALSALLPLLPGTPVDSLPPPLPPPPP-------PPPPPRPVLPPP----APKVEITPEP 337
++L A P + + LPP P P PP P P + P AP+ PE
Sbjct: 1431 KSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPE---EPER 1487
Query: 338 VSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPT 389
+ + ++ PR+ + R PP+ P PP RR P+
Sbjct: 1488 LPLHVRFLENC---------QPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPS 1530
Score = 41.2 bits (95), Expect = 0.002
Identities = 69/282 (24%), Positives = 97/282 (34%), Gaps = 32/282 (11%)
Query: 91 LARVPHSTQGAGPAAEDAFSAE---EETIFAILGPGVAA-------PGAGAGAEEPPAAP 140
L VP A P D+ ++ ++ A L G +A PG A A PAAP
Sbjct: 1602 LPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAP 1661
Query: 141 SSQPPPPSACPQRYVLSEDRRE-DRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKE 199
P PP + R D +T + + SS A + GG
Sbjct: 1662 QPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLS---AEGGGSAGGGGGAGAGV 1718
Query: 200 RESPPPSALQPVQLPRLAL----SPPPPAPPLPPPPP------LAQVAPSPPSPPPPPRP 249
P L A +P PP PP P L P P R
Sbjct: 1719 ASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRD 1778
Query: 250 PPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPP 309
P T + P++ A + A+R +G G+A A+ +P +P SLP
Sbjct: 1779 PVT--PTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRK 1836
Query: 310 LPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVA 351
L P P PP P LP P +P + A V ++++
Sbjct: 1837 LLPWEEGPGPPPPPLPGP------LAQPQASALATVKASIIS 1872
Score = 39.3 bits (90), Expect = 0.006
Identities = 40/140 (28%), Positives = 54/140 (38%), Gaps = 28/140 (20%)
Query: 263 LRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRP 322
L +Q++ A + L K S +LS +PG+ + +PPP P PP PP
Sbjct: 884 LMLRQKSIGAAEDDRPYLAPPAMKFSRSLS-----VPGS--EDIPPP--PTTSPPEPPYS 934
Query: 323 VLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPP------------- 369
P P+ +TP P G + A +P S +G P PP
Sbjct: 935 TPPVPSSSGRLTPSPRGGPFNPGSGGPLPAS----SPASFDG-PSPPDTRVGSREKSLYH 989
Query: 370 PAPLPP-HDSPPHKRRKGFP 388
PLPP H PPH P
Sbjct: 990 SGPLPPAHHHPPHHHHHHAP 1009
Score = 37.0 bits (84), Expect = 0.031
Identities = 55/223 (24%), Positives = 76/223 (34%), Gaps = 41/223 (18%)
Query: 202 SPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVA---PSPPSPPPPPRPPPTLSASDP 258
S PP+A V +A+ P P PLP L + P PPPPP P P
Sbjct: 1804 SGPPTA--GVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQAS 1861
Query: 259 SLDFLRAQ--QETANAIRELAGTL--------------------RQGLAKLSEALSAL-- 294
+L ++A E ++ +++ G+ G + + E S+L
Sbjct: 1862 ALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQR 1921
Query: 295 -------LPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDG 347
L PV SL P PP PP P + P A P S A+
Sbjct: 1922 QRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTA---AAAPGATSPSASSSST 1978
Query: 348 AVVAARGV--IIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFP 388
+ +GV + P AP P P H P R P
Sbjct: 1979 STRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLP 2021
Score = 37.0 bits (84), Expect = 0.031
Identities = 61/223 (27%), Positives = 78/223 (34%), Gaps = 27/223 (12%)
Query: 134 EEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE----PWARPSC-- 187
EE P P P P A PQ L+ + +S + G SS PWAR
Sbjct: 1841 EEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGG 1900
Query: 188 --TPQEGGCPRPKERESP-------PPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAP 238
GG ER S S + P +L P PPLPP P V
Sbjct: 1901 GGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGV-- 1958
Query: 239 SPPSPPPPPRPPPTLSASDPSLDFLRAQQ-ETANAIRELA---GTLRQGLAKLSEA-LSA 293
SP + P P+ S+S S L+ + E + A L K+S A +
Sbjct: 1959 SPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPS 2018
Query: 294 LLPLLPGTPV-----DSLPPPLPPPPPPPPPPRPVLPPPAPKV 331
LP+LP P+ D P P PV PP P +
Sbjct: 2019 SLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGI 2061
Score = 33.9 bits (76), Expect = 0.27
Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 10/64 (15%)
Query: 319 PPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEG-APRPPP-APLPPH 376
PPRP++ P K P+ G +AAR + SE G AP+PPP P P +
Sbjct: 1334 PPRPLVHPLTGKALDPASPL--------GLALAARERALKESSEGGGAPQPPPRPPSPRY 1385
Query: 377 DSPP 380
++PP
Sbjct: 1386 EAPP 1389
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 73.2 bits (178), Expect = 4e-13
Identities = 79/287 (27%), Positives = 104/287 (36%), Gaps = 85/287 (29%)
Query: 158 EDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLA 217
E+++E+ D K + E P+ +E P P PP+ P LP +
Sbjct: 366 EEKKEEEEKDKEGEEKEERAVAEEMM-PAAEKEEAKLPPPP---LTPPAPSPPPPLPPPS 421
Query: 218 LSPPPPAPPLPPPPPLAQVAPSP-PSPPPPPR-------PPPTLSAS-------DPSLDF 262
SPPPP P PPPP V+P P PSPPPPP PPP + A+ P
Sbjct: 422 TSPPPPLCPPPPPP----VSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPS 477
Query: 263 LRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPR- 321
RA++E A A E GT P TP S PP P P+
Sbjct: 478 QRAEREAARAGPE--GTS------------------PPTPTPSTATGGPPEDSPTVAPKS 517
Query: 322 ------------PVL------------------PPPAPKVEITPEPVSVVAAVVDGAVVA 351
PV+ PP PKVE++P V+ +
Sbjct: 518 TTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSP--------VLRPPITT 569
Query: 352 ARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKS 398
+ V P+ P PP AP PP P ++ R+ RW S
Sbjct: 570 SPPV---PQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTS 613
Score = 67.0 bits (162), Expect = 3e-11
Identities = 82/343 (23%), Positives = 118/343 (34%), Gaps = 63/343 (18%)
Query: 52 RRRVWDGIAAKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSA 111
+RRV G G WK+ Q++ + K+ +EK + A AE+ A
Sbjct: 341 QRRVGSGQG----GSPCWKKQEQKLDDEEEE-KKEEEEKDKEGEEKEERA--VAEEMMPA 393
Query: 112 EEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAH 171
E+ + P + P A + PP P S PPP CP
Sbjct: 394 AEKEEAKLPPPPLTPP---APSPPPPLPPPSTSPPPPLCP-------------------- 430
Query: 172 SKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPP 231
P P P P P +E+E PP + P R P P P
Sbjct: 431 ------PPPPPVSPPPLPSPPPPPAQEEQEESPPPVV-PATCSRKRGRP----PLTPSQR 479
Query: 232 PLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEAL 291
+ A + P PP P P+ + P D ++ ++ +RQ + + A
Sbjct: 480 AEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLK----NIRQFIMPVVSAR 535
Query: 292 SALLPLLPGTPVDSLPP--------PLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAA 343
S+ + P +D PP P+ PP PP P P P P P P S
Sbjct: 536 SSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVP 595
Query: 344 VVDGAVVAARGVIIAPR------SEEGAPRPPPAPLPPHDSPP 380
+ + R ++ P + E P PP P PP SPP
Sbjct: 596 LPE----KRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
Score = 66.6 bits (161), Expect = 4e-11
Identities = 75/292 (25%), Positives = 97/292 (33%), Gaps = 73/292 (25%)
Query: 136 PPAAPSSQPPP-------------PSACPQ---RYVLSEDRREDRRADTSAHSKAGSSSP 179
PP PS PPP P+ C + R L+ +R +R A + +P
Sbjct: 438 PPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP 497
Query: 180 EPWARPSCTPQEGGCPRPKERE---------SPPPSALQP--VQLPRLALSPPPPAPP-- 226
P P++ PK P SA ++ PR + PP PP
Sbjct: 498 TPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV 557
Query: 227 -----LPPP----PPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELA 277
L PP PP+ Q PSPP P PP T + ++ + +RE
Sbjct: 558 EVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP---------VPLPEKRRSILRE-- 606
Query: 278 GTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEI-TPE 336
P SL LPPPPP PPPP PPPAP P
Sbjct: 607 ---------------------PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPL 645
Query: 337 PVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSP--PHKRRKG 386
+ A + ++ P P P P P DSP P R G
Sbjct: 646 LLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697
Score = 54.3 bits (129), Expect = 2e-07
Identities = 59/210 (28%), Positives = 69/210 (32%), Gaps = 18/210 (8%)
Query: 135 EPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGC 194
+ PA S P P+ L E RR R T + P P P P
Sbjct: 575 QEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
Query: 195 PRPKERESPPPSALQPVQLPRLA--------LSPPP-PAPPLPPPPPLAQVAPSPPSPPP 245
P P P P P A L+PPP AP P P P PP+
Sbjct: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP-------PPADDS 687
Query: 246 PPRPPPTLSASDPSLDFLR-AQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVD 304
P P P L R A T E++ L+ + + LL L
Sbjct: 688 PAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQ 747
Query: 305 SLPPPLPPPPPP-PPPPRPVLPPPAPKVEI 333
LP LPPP P PPP P PP K I
Sbjct: 748 LLPQALPPPQPQLQPPPSPQQMPPLEKARI 777
Score = 43.1 bits (100), Expect = 4e-04
Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 53/198 (26%)
Query: 199 ERESPPPSALQPVQLPRLALSPP-----PPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTL 253
E E PP QP P ++ + P PP P L P + V P+PP PPPP +
Sbjct: 2207 EGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSS 2266
Query: 254 SASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPP 313
+ P +R ++ + + R P
Sbjct: 2267 GPASPPRQAIRVKRVSTFSGRS-------------------------------------P 2289
Query: 314 PPPPPPPRPVLPPPAPKVEITPEPVSVVA---AVVDGAVVAARGVIIAPRSEEGAPRPPP 370
P PPP P L E TP+ + + + V RGV+ R E A P
Sbjct: 2290 PAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESP 2349
Query: 371 APLP--------PHDSPP 380
PL P D PP
Sbjct: 2350 GPLQERSPLLPLPEDGPP 2367
Score = 42.7 bits (99), Expect = 6e-04
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 38/182 (20%)
Query: 223 PAPPLPPP----PPLAQVAPSPPSPP--------PPPRPPPTLSASDP---SLDFLRAQQ 267
PAP PP PPL P +P PP P + SA P S R +
Sbjct: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKV 1867
Query: 268 ETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPP-----LPPPPPPPPPPRP 322
+ R G + G + S+L +P P P P P P PPP
Sbjct: 1868 PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSR 1927
Query: 323 VLPPP---APKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPR-PPPAPLPPHDS 378
PP +P++ + P P SVV A + P S E AP P P+P PP D
Sbjct: 1928 WASPPLKTSPQLRVPP-PTSVVTA-------------LTPTSGELAPPGPAPSPPPPEDL 1973
Query: 379 PP 380
P
Sbjct: 1974 GP 1975
Score = 42.7 bits (99), Expect = 6e-04
Identities = 69/278 (24%), Positives = 90/278 (32%), Gaps = 40/278 (14%)
Query: 134 EEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSP---EPWARPSCTPQ 190
E P P+ PPPP + E AD + + P E A +
Sbjct: 1957 ELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSS 2016
Query: 191 EGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPL--------------AQV 236
GG E ES P S + P +S P AP P P A+
Sbjct: 2017 HGGPGDSSEEESSPTSRY--IHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEA 2074
Query: 237 APSPPSPPPPPRPPPTLSAS--DPSLDFLRAQQETANAI-----RELAGTLRQGLAKLSE 289
P PP P + A + D R ++ + I + L G G E
Sbjct: 2075 VQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREE 2134
Query: 290 ALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEI-----TPEPVSVVAAV 344
+L PL G S P P P P AP V + PEP +
Sbjct: 2135 SLPPAPPLANG----SQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSK 2190
Query: 345 VDGAVVAARGVIIAPRSEEGAPRPPPA---PLPPHDSP 379
+ +V G + + EG P PPP PLPP SP
Sbjct: 2191 I--ILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISP 2226
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/282 (21%), Positives = 93/282 (32%), Gaps = 52/282 (18%)
Query: 137 PAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPR 196
P AP +PPP P E R + H +P G P
Sbjct: 674 PEAPEPEPPPADDSPAE-------PEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726
Query: 197 PKERESPPPSALQPVQLPRLALSP---PPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTL 253
LQP+Q + L P PPP P L PP PSP PP +
Sbjct: 727 LSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPP-------PSPQQMPPLEK---AR 776
Query: 254 SASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPP 313
A SL +++ + ++ L + + + ++A +PL PG ++ + +
Sbjct: 777 IAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQI 836
Query: 314 PPPPP--------------PPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAP 359
P P P P P+++ +V A+ AR ++
Sbjct: 837 SDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAV-------ALGQARAMV--- 886
Query: 360 RSEEGAPRPPPAP------LPPHDSPPHKRRKGFPTRKRRGR 395
E PR P L D+ + P+R RRG+
Sbjct: 887 --PEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGK 926
Score = 38.5 bits (88), Expect = 0.011
Identities = 45/147 (30%), Positives = 56/147 (38%), Gaps = 21/147 (14%)
Query: 119 ILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSS 178
+L PG + +PP P S PP A P+ + S R + S G S
Sbjct: 1826 VLVPGAPERHSPIQNLDPPLRPDSGSAPPPA-PRSF--SGARIKVPNYSPSRRPLGGVSF 1882
Query: 179 ---PEPWARPSCT---PQEGGCPRPKE-RESPPPSALQPVQLPRLALSPPPPAPP---LP 228
P P + S T P G P R S PS L P P SPP P +P
Sbjct: 1883 GPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP 1942
Query: 229 PP--------PPLAQVAPSPPSPPPPP 247
PP P ++AP P+P PPP
Sbjct: 1943 PPTSVVTALTPTSGELAPPGPAPSPPP 1969
Score = 34.7 bits (78), Expect = 0.16
Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 34/114 (29%)
Query: 229 PPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLS 288
PPP LA VAP+PP P R ++ T ++ L LR+ A +
Sbjct: 162 PPPRLADVAPTPPKTPARK----------------RGEEGTERMVQALTELLRRAQAPQA 205
Query: 289 EALSALLPLLPGTPVDSLPPPLPPPP-----------------PPPPPPRPVLP 325
A P P PP P P P P PP PV+P
Sbjct: 206 PRSRACEPSTPRRS-RGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
Score = 33.5 bits (75), Expect = 0.35
Identities = 54/232 (23%), Positives = 71/232 (30%), Gaps = 63/232 (27%)
Query: 102 GPAAEDAF---SAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSE 158
GP E A + E +TI P PG E+PP P P+R+ +
Sbjct: 1787 GPREEPAHLEAAEENQTIVHSPAPSSEPPGG----EDPPLDTDVLVP---GAPERHSPIQ 1839
Query: 159 DRREDRRADTSA------HSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQ 212
+ R D+ + S +G+ P PS P G P P S +
Sbjct: 1840 NLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIP 1899
Query: 213 LPRLALSPPPP------APPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQ 266
P PP +P P PPP +P + P PPPT
Sbjct: 1900 TVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPT-------------- 1945
Query: 267 QETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPP 318
++AL P L PP P P PPPP
Sbjct: 1946 ----------------------SVVTALTP-----TSGELAPPGPAPSPPPP 1970
Score = 32.7 bits (73), Expect = 0.59
Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 30/119 (25%)
Query: 297 LLPG-----TPVDSLPPPLPPPPPPPPPPRPVLPPPA----PKVEITPEPVSVVAAVVDG 347
L+PG +P+ +L PPL P PPP P A P + P+
Sbjct: 1827 LVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLG-------- 1878
Query: 348 AVVAARGVIIAPRSEEGAPRP-----PPAPLPPHDSPPHKRRKGFPTRKR--RGRWKSP 399
GV P G+P P P +PP + R+ P R RW SP
Sbjct: 1879 ------GVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASP 1931
Score = 32.3 bits (72), Expect = 0.78
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 10/111 (9%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE- 180
PG P GAGA P + P P S R +R + S P
Sbjct: 1040 PGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGG 1099
Query: 181 PWARPSCTPQEGGCP--RPKERESPPPSALQPV-------QLPRLALSPPP 222
P A TP+E P P+E+ P LQPV +L + AL+P P
Sbjct: 1100 PPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDALAPGP 1150
Score = 32.3 bits (72), Expect = 0.78
Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 6/55 (10%)
Query: 179 PEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPL 233
P WA P P+ R PP S + + L+PP PAP PPP L
Sbjct: 1925 PSRWASPPLKTS------PQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDL 1973
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 71.6 bits (174), Expect = 1e-12
Identities = 77/260 (29%), Positives = 94/260 (36%), Gaps = 55/260 (21%)
Query: 104 AAEDAFSAEEETIFAILGPGVAAP---------------GAGAGAEEPPAAPSSQ----- 143
AA A S E L PG A P G G G PP+AP+SQ
Sbjct: 278 AASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALP 337
Query: 144 PPP----PSACPQRYVLSEDRREDRR-------ADTSAHSKAGSSSPEPWARPSCTPQE- 191
PPP P + P+ +S +R A + ++ PW P P++
Sbjct: 338 PPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQI 397
Query: 192 GGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPP 251
P P+ P P+ L P P P P+ P PP Q P P PPP PPP
Sbjct: 398 HSAPGPRR---PAPALLAP---PTFIFPAPTNGEPMRPGPPGLQELP----PLPPPTPPP 447
Query: 252 TLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALS--ALLPLLPGTPVDSLPPP 309
TL A Q T + A L GL AL+ A L P D P P
Sbjct: 448 TLQPP--------ALQPTPLPV---APPLTPGLGHKESALAPTAAPALPPALAADQAPAP 496
Query: 310 LPPPPPPPPPPRPVLPPPAP 329
P P P P P + PAP
Sbjct: 497 SPAPAPTVAEPSPPVSAPAP 516
Score = 48.5 bits (114), Expect = 1e-05
Identities = 88/361 (24%), Positives = 108/361 (29%), Gaps = 125/361 (34%)
Query: 137 PAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQ-----E 191
P APS PPP L +R+ R T A + S E A P Q
Sbjct: 158 PRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRAR 217
Query: 192 GGCP---------RPKERESPPPSALQPVQLPRLALSPPPPAP----------------- 225
GG P +P + ES + R +L+PP +
Sbjct: 218 GGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLF 277
Query: 226 ---------------PLPP--PPPLAQVA----------------PSPPSPPP------P 246
PLPP PL +V+ PPS P P
Sbjct: 278 AASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALP 337
Query: 247 PRPPPTLSASDPSLDFLRAQQETANAIRELA-----GTLRQGLAKLS------------- 288
P P T S P D++ A R G R+ A LS
Sbjct: 338 PPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQI 397
Query: 289 -------EALSALL--------------PLLPGTPVDSLPPPLPPPPPPP--------PP 319
ALL P+ PG P PPLPPP PPP P
Sbjct: 398 HSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPT 457
Query: 320 PRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSP 379
P PV PP P + ++ AA +AA + AP P PAP SP
Sbjct: 458 PLPVAPPLTPGLGHKESALAPTAAPALPPALAA--------DQAPAPSPAPAPTVAEPSP 509
Query: 380 P 380
P
Sbjct: 510 P 510
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/156 (27%), Positives = 56/156 (35%), Gaps = 38/156 (24%)
Query: 122 PGVAAPGAGAGAEEPPAAPSSQP-----PPPSACPQRYVLSEDRREDRRADTSAHSKAGS 176
PG A P EP A+PS+ P P P P E + AG+
Sbjct: 52 PGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPE--------EAAAVSAPPPAPAGT 103
Query: 177 SSPEP--WARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLA 234
P P W +P+ TP P + ++ PP PL PPPP
Sbjct: 104 LLPGPSKWQKPAGTPV--------------PRIRRLLEASHRGQGDPPSLRPLKPPPPPR 149
Query: 235 QVA-----PSPPSPPPPP----RPPPTLSASDPSLD 261
Q++ P PS PPP +PPP L + D
Sbjct: 150 QLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPAD 185
Score = 41.6 bits (96), Expect = 0.001
Identities = 51/195 (26%), Positives = 69/195 (35%), Gaps = 31/195 (15%)
Query: 143 QPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE------PWARPSCTPQEGGCPR 196
Q P + R V DR D R + + S + W S TP G
Sbjct: 5 QSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPP--GLMV 62
Query: 197 PKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSAS 256
P+E ++ P + P+ L R P+P +PPP A V+ PP+P P P+
Sbjct: 63 PREPQASPSTL--PLTLER-------PSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQK 113
Query: 257 DPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVD--SLPPPLPPPP 314
R IR L +G +L PL P P S+ +P P
Sbjct: 114 PAGTPVPR--------IRRLLEASHRGQGDPP----SLRPLKPPPPPRQLSVKDTVPRAP 161
Query: 315 PPPPPPRPVLPPPAP 329
PPP PP P
Sbjct: 162 SQFPPPLETWKPPPP 176
Score = 35.4 bits (80), Expect = 0.092
Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 9/114 (7%)
Query: 289 EALSALLPLLPGTPVDSLPPP---LPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVV 345
+A + LPL P +PPP PPP P +LP P+ + PV + ++
Sbjct: 67 QASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLL 126
Query: 346 DGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP 399
+ + RG P P PPP L D+ P + P + WK P
Sbjct: 127 E---ASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLE---TWKPP 174
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 71.2 bits (173), Expect = 2e-12
Identities = 69/260 (26%), Positives = 92/260 (35%), Gaps = 38/260 (14%)
Query: 127 PGAGAGAEEPPAAPSSQPPPPSACPQ--RYVLSEDRREDRRADTSAHSKAGSSSPEPWAR 184
P A ++P P P PS+ Q R V+ + E++ A+ + P
Sbjct: 307 PQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLP 366
Query: 185 PSCTPQEGGCPRPKER-ESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSP 243
P+ P + P E+ PP + LP++ + PP P+ PPPL P P
Sbjct: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPL------PHRP 420
Query: 244 PPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPV 303
PPPP PS ++ T++ + Q + K LP G P
Sbjct: 421 PPPP----------PS-SYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPA 469
Query: 304 DSLPPPLPPPPPPPPPPRPVLPPPA--PKVEITPEPVSVVAAVVDGAVVAARGVIIAPRS 361
P PP PPPPP P PPPA P I P P
Sbjct: 470 HLPYHPHVYPPNPPPPPVP--PPPASFPPPAIPPPTPGYPPP--------------PPTY 513
Query: 362 EEGAPRPPPAPLPPHDSPPH 381
P PPP P H PPH
Sbjct: 514 NPNFPPPPPRLPPTHAVPPH 533
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/221 (26%), Positives = 77/221 (34%), Gaps = 61/221 (27%)
Query: 124 VAAPGAGAGAEEPPAAPSSQPPPPSACPQRYV---------LSEDRREDRRADTSAHSKA 174
+ P A +PP P PPPP P Y+ +S + + ++ +
Sbjct: 401 IPPPAHPAPVHQPPPLPHRPPPPP---PSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPS 457
Query: 175 GSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLA 234
+ P + P+ P P PPP P P A+ PPP P PPPPP
Sbjct: 458 YGALPPAYGPPAHLPYHPHVYPPNP--PPPPVPPPPASFPPPAI--PPPTPGYPPPPPTY 513
Query: 235 QVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSAL 294
+P PPPPPR PPT A+
Sbjct: 514 ----NPNFPPPPPRLPPT---------------------------------------HAV 530
Query: 295 LPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITP 335
P P P LPP PPP PP +P +PPP P + P
Sbjct: 531 PPHPP--PGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/181 (26%), Positives = 59/181 (32%), Gaps = 39/181 (21%)
Query: 225 PPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELA--GTLRQ 282
P L P P + QV S PS P P P+ AQQ + + + R
Sbjct: 277 PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRA 336
Query: 283 GLAKLSEALSALLPLLPGTP-VDSLPPPLPPPPPPP-------------PPPRPVLPPPA 328
+ E A P P P +++ PPLPP PPP PP PV
Sbjct: 337 VVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDL 396
Query: 329 PKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFP 388
PKV+I P P +PPP P P PP G
Sbjct: 397 PKVQIPP-----------------------PAHPAPVHQPPPLPHRPPPPPPSSYMTGMS 433
Query: 389 T 389
T
Sbjct: 434 T 434
Score = 33.5 bits (75), Expect = 0.35
Identities = 29/103 (28%), Positives = 33/103 (32%), Gaps = 34/103 (33%)
Query: 136 PPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCP 195
PP P PPPP+ P + P P P P P
Sbjct: 500 PPPTPGYPPPPPTYNP------------------------NFPPPP---PRLPPTHAVPP 532
Query: 196 RPKERESPPPSALQPVQLPRLALSP--PPPAPPLPPPPPLAQV 236
P PP L P P A+ P PP PP PPP + V
Sbjct: 533 HP-----PPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 70.9 bits (172), Expect = 2e-12
Identities = 74/234 (31%), Positives = 89/234 (38%), Gaps = 44/234 (18%)
Query: 198 KERESPPPSALQ-PVQLPRLALSPPPPAPPLP--------PPPPLAQVAPSPPSPPPPPR 248
KE S +A+ P +P A P PPAPPLP PPP PP PPPPP
Sbjct: 551 KEMASLSAAAITVPPSVPSRA--PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP 608
Query: 249 PPP----TLSASDPSLDFLRAQQE----TANAIRELAGTLRQGLAKLSEALSALLPLLPG 300
PPP +S PSL A + +A L +G+ S + LPG
Sbjct: 609 PPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS------SLPG 662
Query: 301 TPVDSLPPPLP-----PPPPPPPPPRPVLPPPAPK------VEITPEPVSVVAAVVDGAV 349
PPPLP PPPPPP P +PPP P + P P+ +
Sbjct: 663 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 722
Query: 350 VAARGVIIAPRSEEGAPRPPP-------APLPPHDSPPHKRRKGFPTRKRRGRW 396
I P G P PPP AP+ P P K K + RR W
Sbjct: 723 FPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKP-EVQLRRPNW 775
Score = 70.1 bits (170), Expect = 3e-12
Identities = 70/236 (29%), Positives = 84/236 (35%), Gaps = 77/236 (32%)
Query: 129 AGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCT 188
+ A PP+ PS P PP+ +G+ P P A
Sbjct: 557 SAAAITVPPSVPSRAPVPPA-------------------PPLPGDSGTIIPPPPA----- 592
Query: 189 PQEGGCPRPKERESPPPSAL-------QPVQLP-RLALSPPPPA---PPLPPPPPLAQVA 237
P + P P PPP L P LP A+SPPPP +PPPPPL +
Sbjct: 593 PGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGV 652
Query: 238 --PSPPS-------PPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLS 288
PSP S PPPPP P P L G S
Sbjct: 653 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPP---------------PLPG---------S 688
Query: 289 EALSALLPLLPGTPVDSLPPPLPP-------PPPPPPPPRPVLPPPAPKVEITPEP 337
+ P LPG +PPP PP PPPPP P P +PPP P + + P P
Sbjct: 689 AGIPPPPPPLPGEA--GMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 742
Score = 66.2 bits (160), Expect = 5e-11
Identities = 63/191 (32%), Positives = 78/191 (40%), Gaps = 38/191 (19%)
Query: 162 EDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERES--PPPSALQPVQLPRLALS 219
ED + + ++ S A + P + PS P P P + + PPP A P
Sbjct: 547 EDAKKEMASLSAAAITVPP--SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP 604
Query: 220 PPPPAPPLP------PPPPL---AQVAPSPP------SPPPPPRPPPTLSASDPSLDFLR 264
PPPP PPLP PP L ++P PP PPPPP P S SL
Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 664
Query: 265 AQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTP-VDSLPPPLP-----PPPPPPP 318
A L G+ R + P LPG+ + PPPLP PPPPPP
Sbjct: 665 AIPPPP----PLPGSAR---------IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL 711
Query: 319 PPRPVLPPPAP 329
P P +PPP P
Sbjct: 712 PGGPGIPPPPP 722
Score = 65.9 bits (159), Expect = 6e-11
Identities = 64/221 (28%), Positives = 74/221 (33%), Gaps = 73/221 (33%)
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE 180
G + P A + PP P PPPP P +S + S S P
Sbjct: 584 GTIIPPPPAPGDSTTPPPPPP-PPPPPPPLPGGVCIS--------SPPSLPGGTAISPPP 634
Query: 181 PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPL----PPPPPLAQV 236
P + + P P P+ P PS+L A+ PPPP P PPPPPL
Sbjct: 635 PLSGDATIPPPP--PLPEGVGIPSPSSLP----GGTAIPPPPPLPGSARIPPPPPPLPGS 688
Query: 237 APSPPSPPP-------PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSE 289
A PP PPP PP PPP
Sbjct: 689 AGIPPPPPPLPGEAGMPPPPPP-------------------------------------- 710
Query: 290 ALSALLPLLPGTPVDSLPPPLPPPPP-PPPPPRPVLPPPAP 329
LPG P PPP P P PPPPP +PPP P
Sbjct: 711 --------LPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 70.9 bits (172), Expect = 2e-12
Identities = 74/234 (31%), Positives = 89/234 (38%), Gaps = 44/234 (18%)
Query: 198 KERESPPPSALQ-PVQLPRLALSPPPPAPPLP--------PPPPLAQVAPSPPSPPPPPR 248
KE S +A+ P +P A P PPAPPLP PPP PP PPPPP
Sbjct: 560 KEMASLSAAAITVPPSVPSRA--PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP 617
Query: 249 PPP----TLSASDPSLDFLRAQQE----TANAIRELAGTLRQGLAKLSEALSALLPLLPG 300
PPP +S PSL A + +A L +G+ S + LPG
Sbjct: 618 PPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS------SLPG 671
Query: 301 TPVDSLPPPLP-----PPPPPPPPPRPVLPPPAPK------VEITPEPVSVVAAVVDGAV 349
PPPLP PPPPPP P +PPP P + P P+ +
Sbjct: 672 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 731
Query: 350 VAARGVIIAPRSEEGAPRPPP-------APLPPHDSPPHKRRKGFPTRKRRGRW 396
I P G P PPP AP+ P P K K + RR W
Sbjct: 732 FPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKP-EVQLRRPNW 784
Score = 70.1 bits (170), Expect = 3e-12
Identities = 70/236 (29%), Positives = 84/236 (35%), Gaps = 77/236 (32%)
Query: 129 AGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCT 188
+ A PP+ PS P PP+ +G+ P P A
Sbjct: 566 SAAAITVPPSVPSRAPVPPA-------------------PPLPGDSGTIIPPPPA----- 601
Query: 189 PQEGGCPRPKERESPPPSAL-------QPVQLP-RLALSPPPPA---PPLPPPPPLAQVA 237
P + P P PPP L P LP A+SPPPP +PPPPPL +
Sbjct: 602 PGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGV 661
Query: 238 --PSPPS-------PPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLS 288
PSP S PPPPP P P L G S
Sbjct: 662 GIPSPSSLPGGTAIPPPPPLPGSARIPPPPP---------------PLPG---------S 697
Query: 289 EALSALLPLLPGTPVDSLPPPLPP-------PPPPPPPPRPVLPPPAPKVEITPEP 337
+ P LPG +PPP PP PPPPP P P +PPP P + + P P
Sbjct: 698 AGIPPPPPPLPGEA--GMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPP 751
Score = 66.2 bits (160), Expect = 5e-11
Identities = 63/191 (32%), Positives = 78/191 (40%), Gaps = 38/191 (19%)
Query: 162 EDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERES--PPPSALQPVQLPRLALS 219
ED + + ++ S A + P + PS P P P + + PPP A P
Sbjct: 556 EDAKKEMASLSAAAITVPP--SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP 613
Query: 220 PPPPAPPLP------PPPPL---AQVAPSPP------SPPPPPRPPPTLSASDPSLDFLR 264
PPPP PPLP PP L ++P PP PPPPP P S SL
Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 673
Query: 265 AQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTP-VDSLPPPLP-----PPPPPPP 318
A L G+ R + P LPG+ + PPPLP PPPPPP
Sbjct: 674 AIPPPP----PLPGSAR---------IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL 720
Query: 319 PPRPVLPPPAP 329
P P +PPP P
Sbjct: 721 PGGPGIPPPPP 731
Score = 65.9 bits (159), Expect = 6e-11
Identities = 64/221 (28%), Positives = 74/221 (33%), Gaps = 73/221 (33%)
Query: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPE 180
G + P A + PP P PPPP P +S + S S P
Sbjct: 593 GTIIPPPPAPGDSTTPPPPPP-PPPPPPPLPGGVCIS--------SPPSLPGGTAISPPP 643
Query: 181 PWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPL----PPPPPLAQV 236
P + + P P P+ P PS+L A+ PPPP P PPPPPL
Sbjct: 644 PLSGDATIPPPP--PLPEGVGIPSPSSLP----GGTAIPPPPPLPGSARIPPPPPPLPGS 697
Query: 237 APSPPSPPP-------PPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSE 289
A PP PPP PP PPP
Sbjct: 698 AGIPPPPPPLPGEAGMPPPPPP-------------------------------------- 719
Query: 290 ALSALLPLLPGTPVDSLPPPLPPPPP-PPPPPRPVLPPPAP 329
LPG P PPP P P PPPPP +PPP P
Sbjct: 720 --------LPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,243,768
Number of Sequences: 37866
Number of extensions: 2296280
Number of successful extensions: 118257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1652
Number of HSP's successfully gapped in prelim test: 1991
Number of HSP's that attempted gapping in prelim test: 19871
Number of HSP's gapped (non-prelim): 35281
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.