Guide to the Human Genome
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Search of human proteins with 6042196

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6042196 cathepsin F [Homo sapiens]
         (484 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6042196 cathepsin F [Homo sapiens]                                 990   0.0  
gi|23110964 cathepsin W preproprotein [Homo sapiens]                  238   7e-63
gi|22202619 cathepsin L1 preproprotein [Homo sapiens]                 184   2e-46
gi|4503155 cathepsin L1 preproprotein [Homo sapiens]                  184   2e-46
gi|23110957 cathepsin H isoform b precursor [Homo sapiens]            184   2e-46
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]        184   2e-46
gi|23110960 cathepsin L2 preproprotein [Homo sapiens]                 179   5e-45
gi|4503151 cathepsin K preproprotein [Homo sapiens]                   166   6e-41
gi|4557501 cathepsin O preproprotein [Homo sapiens]                   158   1e-38
gi|23110962 cathepsin S preproprotein [Homo sapiens]                  156   5e-38
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]       121   1e-27
gi|22538437 cathepsin B preproprotein [Homo sapiens]                   89   7e-18
gi|22538435 cathepsin B preproprotein [Homo sapiens]                   89   7e-18
gi|22538433 cathepsin B preproprotein [Homo sapiens]                   89   7e-18
gi|22538431 cathepsin B preproprotein [Homo sapiens]                   89   7e-18
gi|4503139 cathepsin B preproprotein [Homo sapiens]                    89   7e-18
gi|22538442 cathepsin Z preproprotein [Homo sapiens]                   66   6e-11
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa...    59   1e-08
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]       54   3e-07
gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro...    40   0.004
gi|9256608 protocadherin beta 14 precursor [Homo sapiens]              35   0.20 
gi|4557367 bleomycin hydrolase [Homo sapiens]                          32   1.3  
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]           32   1.3  
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]           32   1.3  
gi|169204928 PREDICTED: hypothetical protein [Homo sapiens]            32   1.7  
gi|113423861 PREDICTED: hypothetical protein [Homo sapiens]            32   1.7  
gi|113423437 PREDICTED: hypothetical protein [Homo sapiens]            32   1.7  
gi|166197683 phospholipase D3 [Homo sapiens]                           31   2.9  
gi|72534684 phospholipase D3 [Homo sapiens]                            31   2.9  
gi|40255251 hypothetical protein LOC131408 [Homo sapiens]              30   3.8  

>gi|6042196 cathepsin F [Homo sapiens]
          Length = 484

 Score =  990 bits (2559), Expect = 0.0
 Identities = 484/484 (100%), Positives = 484/484 (100%)

Query: 1   MAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRA 60
           MAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRA
Sbjct: 1   MAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRA 60

Query: 61  VLGLVRGRVRRAGQGSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGRHVLL 120
           VLGLVRGRVRRAGQGSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGRHVLL
Sbjct: 61  VLGLVRGRVRRAGQGSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGRHVLL 120

Query: 121 RKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLP 180
           RKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLP
Sbjct: 121 RKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLP 180

Query: 181 VKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLT 240
           VKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLT
Sbjct: 181 VKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLT 240

Query: 241 EEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSV 300
           EEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSV
Sbjct: 241 EEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSV 300

Query: 301 TGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQ 360
           TGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQ
Sbjct: 301 TGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQ 360

Query: 361 GHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPL 420
           GHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPL
Sbjct: 361 GHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPL 420

Query: 421 RPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASS 480
           RPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASS
Sbjct: 421 RPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASS 480

Query: 481 AVVD 484
           AVVD
Sbjct: 481 AVVD 484


>gi|23110964 cathepsin W preproprotein [Homo sapiens]
          Length = 376

 Score =  238 bits (608), Expect = 7e-63
 Identities = 129/339 (38%), Positives = 185/339 (54%), Gaps = 34/339 (10%)

Query: 176 SQDL---PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYG 232
           +QDL   P+++   FK F I +NR+Y S EE   RL +F +N+ +AQ++Q  D GTA++G
Sbjct: 28  AQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFG 87

Query: 233 VTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPE-----WDWRS-KGAVTKV 286
           VT FSDLTEEEF  +Y     R+  G      + +    P E      DWR   GA++ +
Sbjct: 88  VTPFSDLTEEEFGQLY---GYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPI 144

Query: 287 KDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIK 346
           KDQ  C  CWA +  GN+E  W ++    + +S QELLDC +    C GG   +A+  + 
Sbjct: 145 KDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVL 204

Query: 347 NLGGLETEDDYSYQGHMQS--CNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAI 404
           N  GL +E DY +QG +++  C+    +   +I D + L  NE ++A +LA  GPI+V I
Sbjct: 205 NNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTI 264

Query: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSD--------------------V 444
           N   +Q YR G+ +     C P L+DH+VLLVG+G+                        
Sbjct: 265 NMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPT 324

Query: 445 PFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVV 483
           P+W +KNSWG  WGEKGY+ LHRGS  CG+     +A V
Sbjct: 325 PYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTARV 363


>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  184 bits (467), Expect = 2e-46
 Identities = 116/302 (38%), Positives = 163/302 (53%), Gaps = 16/302 (5%)

Query: 194 YNRTYESKEEARWRLSVFVNNMVRAQ-KIQALDRGTAQY--GVTKFSDLTEEEFRTIYLN 250
           +NR Y   EE  WR +V+  NM   +   Q    G   +   +  F D+T EEFR +   
Sbjct: 36  HNRLYGMNEEG-WRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNG 94

Query: 251 TLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFL 310
              RK    K+ Q     + AP   DWR KG VT VK+QG CGSCWAFS TG +EGQ F 
Sbjct: 95  FQNRKPRKGKVFQEPLFYE-APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFR 153

Query: 311 NQGTLLSLSEQELLDCD--KMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNF 368
             G L+SLSEQ L+DC   + ++ C GGL   A+  +++ GGL++E+ Y Y+   +SC +
Sbjct: 154 KTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY 213

Query: 369 SAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSP 426
           + + +       V++ + E+ L   +A  GPISVAI+A      FY+ GI     P CS 
Sbjct: 214 NPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIY--FEPDCSS 271

Query: 427 WLIDHAVLLVGYGNRS----DVPFWAIKNSWGTDWGEKGYYYLHRG-SGACGVNTMASSA 481
             +DH VL+VGYG  S    +  +W +KNSWG +WG  GY  + +     CG+ + AS  
Sbjct: 272 EDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331

Query: 482 VV 483
            V
Sbjct: 332 TV 333


>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  184 bits (467), Expect = 2e-46
 Identities = 116/302 (38%), Positives = 163/302 (53%), Gaps = 16/302 (5%)

Query: 194 YNRTYESKEEARWRLSVFVNNMVRAQ-KIQALDRGTAQY--GVTKFSDLTEEEFRTIYLN 250
           +NR Y   EE  WR +V+  NM   +   Q    G   +   +  F D+T EEFR +   
Sbjct: 36  HNRLYGMNEEG-WRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNG 94

Query: 251 TLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFL 310
              RK    K+ Q     + AP   DWR KG VT VK+QG CGSCWAFS TG +EGQ F 
Sbjct: 95  FQNRKPRKGKVFQEPLFYE-APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFR 153

Query: 311 NQGTLLSLSEQELLDCD--KMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNF 368
             G L+SLSEQ L+DC   + ++ C GGL   A+  +++ GGL++E+ Y Y+   +SC +
Sbjct: 154 KTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY 213

Query: 369 SAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSP 426
           + + +       V++ + E+ L   +A  GPISVAI+A      FY+ GI     P CS 
Sbjct: 214 NPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIY--FEPDCSS 271

Query: 427 WLIDHAVLLVGYGNRS----DVPFWAIKNSWGTDWGEKGYYYLHRG-SGACGVNTMASSA 481
             +DH VL+VGYG  S    +  +W +KNSWG +WG  GY  + +     CG+ + AS  
Sbjct: 272 EDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331

Query: 482 VV 483
            V
Sbjct: 332 TV 333


>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
          Length = 323

 Score =  184 bits (467), Expect = 2e-46
 Identities = 111/300 (37%), Positives = 159/300 (53%), Gaps = 12/300 (4%)

Query: 187 FKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRG--TAQYGVTKFSDLTEEEF 244
           FK+++  + +TY S EE   RL  F +N    +KI A + G  T +  + +FSD++  E 
Sbjct: 23  FKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHTFKMALNQFSDMSFAEI 78

Query: 245 RTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGA-VTKVKDQGMCGSCWAFSVTGN 303
           +  YL +  +     K    +  G   PP  DWR KG  V+ VK+QG CGSCW FS TG 
Sbjct: 79  KHKYLWSEPQNCSATKSNYLRGTGPY-PPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGA 137

Query: 304 VEGQWFLNQGTLLSLSEQELLDC--DKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQG 361
           +E    +  G +LSL+EQ+L+DC  D  +  C GGLPS A+  I    G+  ED Y YQG
Sbjct: 138 LESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQG 197

Query: 362 HMQSCNFSAEKAKVYINDSVELS-QNEQKLAAWLAKRGPISVAINAF-GMQFYRHGISRP 419
               C F   KA  ++ D   ++  +E+ +   +A   P+S A         YR GI   
Sbjct: 198 KDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS 257

Query: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMAS 479
                +P  ++HAVL VGYG ++ +P+W +KNSWG  WG  GY+ + RG   CG+   AS
Sbjct: 258 TSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACAS 317


>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
          Length = 335

 Score =  184 bits (467), Expect = 2e-46
 Identities = 111/300 (37%), Positives = 159/300 (53%), Gaps = 12/300 (4%)

Query: 187 FKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRG--TAQYGVTKFSDLTEEEF 244
           FK+++  + +TY S EE   RL  F +N    +KI A + G  T +  + +FSD++  E 
Sbjct: 35  FKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHTFKMALNQFSDMSFAEI 90

Query: 245 RTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGA-VTKVKDQGMCGSCWAFSVTGN 303
           +  YL +  +     K    +  G   PP  DWR KG  V+ VK+QG CGSCW FS TG 
Sbjct: 91  KHKYLWSEPQNCSATKSNYLRGTGPY-PPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGA 149

Query: 304 VEGQWFLNQGTLLSLSEQELLDC--DKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQG 361
           +E    +  G +LSL+EQ+L+DC  D  +  C GGLPS A+  I    G+  ED Y YQG
Sbjct: 150 LESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQG 209

Query: 362 HMQSCNFSAEKAKVYINDSVELS-QNEQKLAAWLAKRGPISVAINAF-GMQFYRHGISRP 419
               C F   KA  ++ D   ++  +E+ +   +A   P+S A         YR GI   
Sbjct: 210 KDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS 269

Query: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMAS 479
                +P  ++HAVL VGYG ++ +P+W +KNSWG  WG  GY+ + RG   CG+   AS
Sbjct: 270 TSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACAS 329


>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
          Length = 334

 Score =  179 bits (454), Expect = 5e-45
 Identities = 120/309 (38%), Positives = 164/309 (53%), Gaps = 35/309 (11%)

Query: 193 TYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYG-------VTKFSDLTEEEFR 245
           T+ R Y + EE  WR +V+  NM    K+  L  G    G       +  F D+T EEFR
Sbjct: 35  THRRLYGANEEG-WRRAVWEKNM----KMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFR 89

Query: 246 TI---YLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTG 302
            +   + N   RK    K+ +     DL P   DWR KG VT VK+Q  CGSCWAFS TG
Sbjct: 90  QMMGCFRNQKFRK---GKVFREPLFLDL-PKSVDWRKKGYVTPVKNQKQCGSCWAFSATG 145

Query: 303 NVEGQWFLNQGTLLSLSEQELLDCDKM--DKACMGGLPSNAYSAIKNLGGLETEDDYSYQ 360
            +EGQ F   G L+SLSEQ L+DC +   ++ C GG  + A+  +K  GGL++E+ Y Y 
Sbjct: 146 ALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYV 205

Query: 361 GHMQSCNFSAEKAKVYIND---SVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHG 415
              + C +  E +    ND   +V     E+ L   +A  GPISVA++A     QFY+ G
Sbjct: 206 AVDEICKYRPENS--VANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSG 263

Query: 416 ISRPLRPLCSPWLIDHAVLLVGYG----NRSDVPFWAIKNSWGTDWGEKGYYYLHRG-SG 470
           I     P CS   +DH VL+VGYG    N ++  +W +KNSWG +WG  GY  + +  + 
Sbjct: 264 IY--FEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNN 321

Query: 471 ACGVNTMAS 479
            CG+ T AS
Sbjct: 322 HCGIATAAS 330


>gi|4503151 cathepsin K preproprotein [Homo sapiens]
          Length = 329

 Score =  166 bits (419), Expect = 6e-41
 Identities = 107/304 (35%), Positives = 159/304 (52%), Gaps = 27/304 (8%)

Query: 193 TYNRTYESKEEARWRLSVFVNNM--VRAQKIQA-LDRGTAQYGVTKFSDLTEEEFRTIYL 249
           T+ + Y +K +   R  ++  N+  +    ++A L   T +  +    D+T EE      
Sbjct: 32  THRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEE------ 85

Query: 250 NTLLRKEPGNK--MKQAKSVGDLAPPEW--------DWRSKGAVTKVKDQGMCGSCWAFS 299
             +++K  G K  +  ++S   L  PEW        D+R KG VT VK+QG CGSCWAFS
Sbjct: 86  --VVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFS 143

Query: 300 VTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSY 359
             G +EGQ     G LL+LS Q L+DC   +  C GG  +NA+  ++   G+++ED Y Y
Sbjct: 144 SVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPY 203

Query: 360 QGHMQSCNFSAEKAKVYINDSVELSQ-NEQKLAAWLAKRGPISVAINA--FGMQFYRHGI 416
            G  +SC ++            E+ + NE+ L   +A+ GP+SVAI+A     QFY  G+
Sbjct: 204 VGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGV 263

Query: 417 SRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRG-SGACGVN 475
                  C+   ++HAVL VGYG +     W IKNSWG +WG KGY  + R  + ACG+ 
Sbjct: 264 Y--YDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIA 321

Query: 476 TMAS 479
            +AS
Sbjct: 322 NLAS 325


>gi|4557501 cathepsin O preproprotein [Homo sapiens]
          Length = 321

 Score =  158 bits (399), Expect = 1e-38
 Identities = 99/299 (33%), Positives = 153/299 (51%), Gaps = 11/299 (3%)

Query: 190 FVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYL 249
           F  T+ R+ E +E A +R S+  N       +   +  TA YG+ +FS L  EEF+ IYL
Sbjct: 29  FTPTWPRSRE-REAAAFRESL--NRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYL 85

Query: 250 NTLLRKEPGNKMKQAKSVGDLAPP-EWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQW 308
            +   K P    +   S+ +++ P  +DWR K  VT+V++Q MCG CWAFSV G VE  +
Sbjct: 86  RSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAY 145

Query: 309 FLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLG-GLETEDDYSYQGHMQSCN 367
            +    L  LS Q+++DC   +  C GG   NA + +  +   L  + +Y ++     C+
Sbjct: 146 AIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCH 205

Query: 368 -FSAEKAKVYIN--DSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLC 424
            FS   +   I    + + S  E ++A  L   GP+ V ++A   Q Y  GI   ++  C
Sbjct: 206 YFSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGI---IQHHC 262

Query: 425 SPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVV 483
           S    +HAVL+ G+      P+W ++NSWG+ WG  GY ++  GS  CG+    SS  V
Sbjct: 263 SSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV 321


>gi|23110962 cathepsin S preproprotein [Homo sapiens]
          Length = 331

 Score =  156 bits (394), Expect = 5e-38
 Identities = 91/295 (30%), Positives = 150/295 (50%), Gaps = 9/295 (3%)

Query: 193 TYNRTYESKEEARWRLSVFVNNM--VRAQKIQ-ALDRGTAQYGVTKFSDLTEEEFRTIYL 249
           TY + Y+ K E   R  ++  N+  V    ++ ++   +   G+    D+T EE  ++  
Sbjct: 34  TYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMS 93

Query: 250 NTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWF 309
           +  +  +    +    +   + P   DWR KG VT+VK QG CG+CWAFS  G +E Q  
Sbjct: 94  SLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLK 153

Query: 310 LNQGTLLSLSEQELLDCDKM---DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSC 366
           L  G L+SLS Q L+DC      +K C GG  + A+  I +  G++++  Y Y+   Q C
Sbjct: 154 LKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKC 213

Query: 367 NFSAEKAKVYINDSVELSQ-NEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCS 425
            + ++      +   EL    E  L   +A +GP+SV ++A    F+ +       P C+
Sbjct: 214 QYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT 273

Query: 426 PWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSG-ACGVNTMAS 479
              ++H VL+VGYG+ +   +W +KNSWG ++GE+GY  + R  G  CG+ +  S
Sbjct: 274 Q-NVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPS 327


>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
          Length = 463

 Score =  121 bits (304), Expect = 1e-27
 Identities = 92/327 (28%), Positives = 153/327 (46%), Gaps = 37/327 (11%)

Query: 182 KMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTE 241
           K+ +  +N  +       S+E+   RL  + +N V+A  I A+ +         ++  T 
Sbjct: 141 KVGTASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKA--INAIQKS--------WTATTY 190

Query: 242 EEFRTIYLNTLLRKEPGN-----KMKQAKSVGDLA------PPEWDWRSKGA---VTKVK 287
            E+ T+ L  ++R+  G+     + K A    ++       P  WDWR+      V+ V+
Sbjct: 191 MEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVR 250

Query: 288 DQGMCGSCWAFSVTGNVEGQWFL--NQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 345
           +Q  CGSC++F+  G +E +  +  N      LS QE++ C +  + C GG P       
Sbjct: 251 NQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKY 310

Query: 346 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQ-----NEQKLAAWLAKRGPI 400
               GL  E  + Y G    C    +  + Y ++   +       NE  +   L   GP+
Sbjct: 311 AQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPM 370

Query: 401 SVAINAFG-MQFYRHGISRP--LRPLCSPW-LIDHAVLLVGYG--NRSDVPFWAIKNSWG 454
           +VA   +     Y+ GI     LR   +P+ L +HAVLLVGYG  + S + +W +KNSWG
Sbjct: 371 AVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWG 430

Query: 455 TDWGEKGYYYLHRGSGACGVNTMASSA 481
           T WGE GY+ + RG+  C + ++A +A
Sbjct: 431 TGWGENGYFRIRRGTDECAIESIAVAA 457


>gi|22538437 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 58/237 (24%), Positives = 103/237 (43%), Gaps = 40/237 (16%)

Query: 277 WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSL--SEQELLDC--DKMDKA 332
           W     + +++DQG CGSCWAF     +  +  ++    +S+  S ++LL C        
Sbjct: 90  WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149

Query: 333 CMGGLPSNAYS--AIKNL--GGLETED-----------DYSYQGHMQSCNFSAEKAKV-- 375
           C GG P+ A++    K L  GGL               ++   G    C    +  K   
Sbjct: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209

Query: 376 ---------------YINDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRP 419
                          Y  +S  +S +E+ + A + K GP+  A + +     Y+ G+   
Sbjct: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV--- 266

Query: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNT 476
            + +    +  HA+ ++G+G  +  P+W + NSW TDWG+ G++ + RG   CG+ +
Sbjct: 267 YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIES 323


>gi|22538435 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 58/237 (24%), Positives = 103/237 (43%), Gaps = 40/237 (16%)

Query: 277 WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSL--SEQELLDC--DKMDKA 332
           W     + +++DQG CGSCWAF     +  +  ++    +S+  S ++LL C        
Sbjct: 90  WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149

Query: 333 CMGGLPSNAYS--AIKNL--GGLETED-----------DYSYQGHMQSCNFSAEKAKV-- 375
           C GG P+ A++    K L  GGL               ++   G    C    +  K   
Sbjct: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209

Query: 376 ---------------YINDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRP 419
                          Y  +S  +S +E+ + A + K GP+  A + +     Y+ G+   
Sbjct: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV--- 266

Query: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNT 476
            + +    +  HA+ ++G+G  +  P+W + NSW TDWG+ G++ + RG   CG+ +
Sbjct: 267 YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIES 323


>gi|22538433 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 58/237 (24%), Positives = 103/237 (43%), Gaps = 40/237 (16%)

Query: 277 WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSL--SEQELLDC--DKMDKA 332
           W     + +++DQG CGSCWAF     +  +  ++    +S+  S ++LL C        
Sbjct: 90  WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149

Query: 333 CMGGLPSNAYS--AIKNL--GGLETED-----------DYSYQGHMQSCNFSAEKAKV-- 375
           C GG P+ A++    K L  GGL               ++   G    C    +  K   
Sbjct: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209

Query: 376 ---------------YINDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRP 419
                          Y  +S  +S +E+ + A + K GP+  A + +     Y+ G+   
Sbjct: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV--- 266

Query: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNT 476
            + +    +  HA+ ++G+G  +  P+W + NSW TDWG+ G++ + RG   CG+ +
Sbjct: 267 YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIES 323


>gi|22538431 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 58/237 (24%), Positives = 103/237 (43%), Gaps = 40/237 (16%)

Query: 277 WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSL--SEQELLDC--DKMDKA 332
           W     + +++DQG CGSCWAF     +  +  ++    +S+  S ++LL C        
Sbjct: 90  WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149

Query: 333 CMGGLPSNAYS--AIKNL--GGLETED-----------DYSYQGHMQSCNFSAEKAKV-- 375
           C GG P+ A++    K L  GGL               ++   G    C    +  K   
Sbjct: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209

Query: 376 ---------------YINDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRP 419
                          Y  +S  +S +E+ + A + K GP+  A + +     Y+ G+   
Sbjct: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV--- 266

Query: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNT 476
            + +    +  HA+ ++G+G  +  P+W + NSW TDWG+ G++ + RG   CG+ +
Sbjct: 267 YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIES 323


>gi|4503139 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 58/237 (24%), Positives = 103/237 (43%), Gaps = 40/237 (16%)

Query: 277 WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSL--SEQELLDC--DKMDKA 332
           W     + +++DQG CGSCWAF     +  +  ++    +S+  S ++LL C        
Sbjct: 90  WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149

Query: 333 CMGGLPSNAYS--AIKNL--GGLETED-----------DYSYQGHMQSCNFSAEKAKV-- 375
           C GG P+ A++    K L  GGL               ++   G    C    +  K   
Sbjct: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209

Query: 376 ---------------YINDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRP 419
                          Y  +S  +S +E+ + A + K GP+  A + +     Y+ G+   
Sbjct: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV--- 266

Query: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNT 476
            + +    +  HA+ ++G+G  +  P+W + NSW TDWG+ G++ + RG   CG+ +
Sbjct: 267 YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIES 323


>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
          Length = 303

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 62/221 (28%), Positives = 93/221 (42%), Gaps = 41/221 (18%)

Query: 272 PPEWDWRSKGAVTKV---KDQGM---CGSCWAFSVTGNV--------EGQWFLNQGTLLS 317
           P  WDWR+   V      ++Q +   CGSCWA + T  +        +G W     TLLS
Sbjct: 63  PKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAW---PSTLLS 119

Query: 318 LSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNF--------- 368
           +  Q ++DC     +C GG   + +    +  G+  E   +YQ   Q C+          
Sbjct: 120 V--QNVIDCGNAG-SCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175

Query: 369 --SAEKAKVY----INDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRPLR 421
                  + Y    + D   LS  E K+ A +   GPIS  I A   +  Y  GI    +
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGRE-KMMAEIYANGPISCGIMATERLANYTGGIYAEYQ 234

Query: 422 PLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGY 462
                  I+H V + G+G      +W ++NSWG  WGE+G+
Sbjct: 235 DTT---YINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGW 272


>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
           sapiens]
          Length = 467

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 68/311 (21%), Positives = 126/311 (40%), Gaps = 50/311 (16%)

Query: 215 MVRAQKIQALDRGTAQYGV---TKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSV---G 268
           +V    I+A+++G   +     + F  +T +E     L T+        M +  +V   G
Sbjct: 141 LVDPDMIKAINQGNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPG 200

Query: 269 DLAPPEWDWRSK--GAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLS--LSEQELL 324
           ++ P  ++   K    + +  DQG C   WAFS       +  ++    ++  LS Q LL
Sbjct: 201 EVLPTAFEASEKWPNLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLL 260

Query: 325 DCDK-MDKACMGGLPSNAYSAIKNLGGLETEDDYSYQG--------------HMQSCNFS 369
            CD    + C GG    A+  ++  G + ++  Y + G              H ++    
Sbjct: 261 SCDTHQQQGCRGGRLDGAWWFLRRRG-VVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRG 319

Query: 370 AEKAKV-----YINDS--------VELSQNEQKLAAWLAKRGPISVAINAFGMQF-YRHG 415
             +A       Y+N++          L  N++++   L + GP+   +      F Y+ G
Sbjct: 320 KRQATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHEDFFLYKGG 379

Query: 416 I--SRPL---RPLCSPWLIDHAVLLVGYGNRS-----DVPFWAIKNSWGTDWGEKGYYYL 465
           I    P+   RP        H+V + G+G  +      + +W   NSWG  WGE+G++ +
Sbjct: 380 IYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRI 439

Query: 466 HRGSGACGVNT 476
            RG   C + +
Sbjct: 440 VRGVNECDIES 450


>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
          Length = 476

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 75/327 (22%), Positives = 124/327 (37%), Gaps = 56/327 (17%)

Query: 205 RWRLSVFVNNMVRAQKIQALDRG----TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGNK 260
           +W+ S  V  +VR++ I+ +++G    TAQ   ++F  +T E+     L TL    P   
Sbjct: 146 QWKCSQHVC-LVRSELIEQVNKGDYGWTAQ-NYSQFWGMTLEDGFKFRLGTL---PPSPM 200

Query: 261 MKQAKSVGDLAPPEWD--------WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312
           +     +    P   D        ++  G      DQ  C + WAFS T +V       Q
Sbjct: 201 LLSMNEMTASLPATTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFS-TASVAADRIAIQ 259

Query: 313 GT---LLSLSEQELLDCDKMDK-ACMGGLPSNAYSAIKNLG------------------- 349
                  +LS Q L+ C   ++  C  G    A+  ++  G                   
Sbjct: 260 SKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWYLRKRGLVSHACYPLFKDQNATNNG 319

Query: 350 -GLETEDDYSYQGHM-QSCNFSAEKA-KVY-INDSVELSQNEQKLAAWLAKRGPISVAIN 405
             + +  D   + H  + C  + EK+ ++Y  +    +S NE ++   + + GP+   + 
Sbjct: 320 CAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQ 379

Query: 406 A------FGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVP-----FWAIKNSWG 454
                  +    YRH  S          L  HAV L G+G           FW   NSWG
Sbjct: 380 VREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWG 439

Query: 455 TDWGEKGYYYLHRGSGACGVNTMASSA 481
             WGE GY+ + RG     +  +  +A
Sbjct: 440 KSWGENGYFRILRGVNESDIEKLIIAA 466


>gi|239744067 PREDICTED: similar to Putative cathepsin L-like
           protein 6 [Homo sapiens]
          Length = 81

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 236 FSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQ 289
           F D+T EEFR +      +K    K  Q + + ++ P   DWR KG VT VKDQ
Sbjct: 25  FGDMTTEEFRQVMNGFQYQKHRNGKQFQERLLLEI-PTSVDWREKGYVTPVKDQ 77


>gi|9256608 protocadherin beta 14 precursor [Homo sapiens]
          Length = 798

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/78 (23%), Positives = 42/78 (53%), Gaps = 10/78 (12%)

Query: 148 ISSLSQNHPDNRNETFSSVISLLNED---------PLSQDLPVKMASIFKN-FVITYNRT 197
           ISS+++  P+N +ET  ++ S+L++D          +  +LP  +   FKN F +   + 
Sbjct: 349 ISSITKRIPENASETLVALFSILDQDSGDNGRMICSIQDNLPFFLKPTFKNFFTLVSEKA 408

Query: 198 YESKEEARWRLSVFVNNM 215
            + + +A + +++ V ++
Sbjct: 409 LDRESQAEYNITITVTDL 426


>gi|4557367 bleomycin hydrolase [Homo sapiens]
          Length = 455

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 4/39 (10%)

Query: 428 LIDHAVLLVGYGNRSD----VPFWAIKNSWGTDWGEKGY 462
           L+ HA+       + D       W ++NSWG D G KGY
Sbjct: 369 LMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGY 407


>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 372 KAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPL 420
           K +++++   EL + E KLAAW+ K    S  ++A G  F R+G S  L
Sbjct: 885 KTRIFLHVLSELKEVEPKLAAWIQKLN--SFGLDATGTFFSRYGASLKL 931


>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 2/49 (4%)

Query: 372 KAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPL 420
           K +++++   EL + E KLAAW+ K    S  ++A G  F R+G S  L
Sbjct: 885 KTRIFLHVLSELKEVEPKLAAWIQKLN--SFGLDATGTFFSRYGASLKL 931


>gi|169204928 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 215

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 11/47 (23%)

Query: 9   SLLGLLPGAVAAPAQPRA---------ASFQAWGPPSPELL--APTR 44
           +++ LLP  VAA A+PRA          S +AW PP P  L  APTR
Sbjct: 104 AIIALLPPHVAAAARPRAETAAVTDGVTSPRAWPPPPPPPLPPAPTR 150


>gi|113423861 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 215

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 11/47 (23%)

Query: 9   SLLGLLPGAVAAPAQPRA---------ASFQAWGPPSPELL--APTR 44
           +++ LLP  VAA A+PRA          S +AW PP P  L  APTR
Sbjct: 104 AIIALLPPHVAAAARPRAETAAVTDGVTSPRAWPPPPPPPLPPAPTR 150


>gi|113423437 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 215

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 11/47 (23%)

Query: 9   SLLGLLPGAVAAPAQPRA---------ASFQAWGPPSPELL--APTR 44
           +++ LLP  VAA A+PRA          S +AW PP P  L  APTR
Sbjct: 104 AIIALLPPHVAAAARPRAETAAVTDGVTSPRAWPPPPPPPLPPAPTR 150


>gi|166197683 phospholipase D3 [Homo sapiens]
          Length = 490

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 11/83 (13%)

Query: 270 LAPPEWDWRSKGAVTKVKDQGMCG---SCWAFSVTGNVEGQWFLNQ-GTLLSLSEQELLD 325
           L     DWRS   +T+VK+ G+     SC A  +T   E  WFL Q G+ +  +     D
Sbjct: 214 LGSANMDWRS---LTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYD 270

Query: 326 C----DKMDKACMGGLPSNAYSA 344
                +   + C+ G P+ AY A
Sbjct: 271 TRYNQETPMEICLNGTPALAYLA 293


>gi|72534684 phospholipase D3 [Homo sapiens]
          Length = 490

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 11/83 (13%)

Query: 270 LAPPEWDWRSKGAVTKVKDQGMCG---SCWAFSVTGNVEGQWFLNQ-GTLLSLSEQELLD 325
           L     DWRS   +T+VK+ G+     SC A  +T   E  WFL Q G+ +  +     D
Sbjct: 214 LGSANMDWRS---LTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYD 270

Query: 326 C----DKMDKACMGGLPSNAYSA 344
                +   + C+ G P+ AY A
Sbjct: 271 TRYNQETPMEICLNGTPALAYLA 293


>gi|40255251 hypothetical protein LOC131408 [Homo sapiens]
          Length = 335

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 330 DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVEL------ 383
           D+  +  LP +  SA ++LG LE +D        +SC   AE+      D   L      
Sbjct: 247 DELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCPPLTG 306

Query: 384 SQNEQKLAAWLAKRGPISV 402
           S   Q+ A+ LA  G +S+
Sbjct: 307 SWERQRQASDLASSGVVSL 325


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,028,145
Number of Sequences: 37866
Number of extensions: 855589
Number of successful extensions: 2455
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2387
Number of HSP's gapped (non-prelim): 38
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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