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Search of human proteins with 6005846
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005846 twinfilin-like protein [Homo sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005846 twinfilin-like protein [Homo sapiens] 705 0.0
gi|40068475 twinfilin 1 [Homo sapiens] 489 e-138
gi|14719392 cofilin 2 [Homo sapiens] 44 3e-04
gi|33946278 cofilin 2 [Homo sapiens] 44 3e-04
gi|58530848 destrin isoform b [Homo sapiens] 43 5e-04
gi|5802966 destrin isoform a [Homo sapiens] 43 5e-04
gi|5031635 cofilin 1 (non-muscle) [Homo sapiens] 41 0.002
gi|4758440 glia maturation factor, gamma [Homo sapiens] 41 0.002
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 37 0.020
gi|169165465 PREDICTED: similar to Destrin (actin depolymerizing... 34 0.17
gi|113415024 PREDICTED: similar to destrin [Homo sapiens] 34 0.17
gi|169165083 PREDICTED: similar to Destrin (actin depolymerizing... 34 0.17
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 34 0.22
gi|221139761 zinc finger protein 853 [Homo sapiens] 32 0.85
gi|134152674 rabaptin, RAB GTPase binding effector protein 1 iso... 32 0.85
gi|221219026 pleckstrin homology-like domain, family B, member 1... 32 1.1
gi|221219024 pleckstrin homology-like domain, family B, member 1... 32 1.1
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 32 1.1
gi|219555649 dullard homolog [Homo sapiens] 31 1.4
gi|31542547 dullard homolog [Homo sapiens] 31 1.4
gi|4758616 jun oncogene [Homo sapiens] 31 1.9
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 31 1.9
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 31 1.9
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 31 1.9
gi|22748757 truncated type I keratin KA21 [Homo sapiens] 30 2.5
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 30 3.2
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 30 3.2
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens] 30 4.2
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 30 4.2
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 30 4.2
>gi|6005846 twinfilin-like protein [Homo sapiens]
Length = 349
Score = 705 bits (1819), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL 60
MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL
Sbjct: 1 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL 60
Query: 61 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE 120
LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE
Sbjct: 61 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE 120
Query: 121 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAF 180
LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAF
Sbjct: 121 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAF 180
Query: 181 PLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFL 240
PLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFL
Sbjct: 181 PLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFL 240
Query: 241 YKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG 300
YKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG
Sbjct: 241 YKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG 300
Query: 301 AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS 349
AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS
Sbjct: 301 AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS 349
>gi|40068475 twinfilin 1 [Homo sapiens]
Length = 384
Score = 489 bits (1258), Expect = e-138
Identities = 225/344 (65%), Positives = 294/344 (85%)
Query: 1 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL 60
M+HQTGI A+E++KE FA+AR G RL+K+ IE+EQLV+G+ +P WD+DYD VLPL
Sbjct: 35 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL 94
Query: 61 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE 120
L+ +QPCY+L+RLDSQNAQG+EW+F+AWSPD+S VR KMLYAATRAT+KKEFGGGHIKDE
Sbjct: 95 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE 154
Query: 121 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAF 180
+FGTVK+D+S GY+K+L S ++PAPLT+AE EL+QI+INEV+T++ V++KHQTLQG+AF
Sbjct: 155 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINEVQTDVGVDTKHQTLQGVAF 214
Query: 181 PLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFL 240
P+ EA +AL++L + +NY+Q+++D++ E I L +T T++ LP R+P+D+ARYHFFL
Sbjct: 215 PISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDSARYHFFL 274
Query: 241 YKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDG 300
YKH+HEGD LES+VFIYSMPGY CSI+ERMLYSSCKSRLL+ VE+ +++ +KIEI +G
Sbjct: 275 YKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIRKIEIDNG 334
Query: 301 AELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGE 344
ELTA+FLY+EVHPKQHA KQ+FAKPKGP GKRG +RLIRGP E
Sbjct: 335 DELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAE 378
>gi|14719392 cofilin 2 [Homo sapiens]
Length = 166
Score = 43.5 bits (101), Expect = 3e-04
Identities = 28/102 (27%), Positives = 58/102 (56%), Gaps = 8/102 (7%)
Query: 30 VVIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQQPCYLLY--RLDSQNAQGFEWLFLA 87
+V E +Q+++G +G +D + + LL Y LY +++ ++ + +F+
Sbjct: 48 IVEEAKQILVG----DIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIF 103
Query: 88 WSPDNSPVRLKMLYAATRATVKKEFGGGHIKDELFGTVKDDL 129
W+P+++P++ KM+YA+++ +KK+F G IK E DD+
Sbjct: 104 WAPESAPLKSKMIYASSKDAIKKKFTG--IKHEWQVNGLDDI 143
>gi|33946278 cofilin 2 [Homo sapiens]
Length = 166
Score = 43.5 bits (101), Expect = 3e-04
Identities = 28/102 (27%), Positives = 58/102 (56%), Gaps = 8/102 (7%)
Query: 30 VVIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQQPCYLLY--RLDSQNAQGFEWLFLA 87
+V E +Q+++G +G +D + + LL Y LY +++ ++ + +F+
Sbjct: 48 IVEEAKQILVG----DIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIF 103
Query: 88 WSPDNSPVRLKMLYAATRATVKKEFGGGHIKDELFGTVKDDL 129
W+P+++P++ KM+YA+++ +KK+F G IK E DD+
Sbjct: 104 WAPESAPLKSKMIYASSKDAIKKKFTG--IKHEWQVNGLDDI 143
>gi|58530848 destrin isoform b [Homo sapiens]
Length = 148
Score = 42.7 bits (99), Expect = 5e-04
Identities = 29/105 (27%), Positives = 58/105 (55%), Gaps = 8/105 (7%)
Query: 30 VVIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQQPCYLLY--RLDSQNAQGFEWLFLA 87
+V E +++++G VG D + + +L + Y LY +++ ++ E +F
Sbjct: 31 IVEEGKEILVG----DVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFL 86
Query: 88 WSPDNSPVRLKMLYAATRATVKKEFGGGHIKDELFGTVKDDLSFA 132
W+P+ +P++ KM+YA+++ +KK+F G IK E +DL+ A
Sbjct: 87 WAPELAPLKSKMIYASSKDAIKKKFQG--IKHECQANGPEDLNRA 129
>gi|5802966 destrin isoform a [Homo sapiens]
Length = 165
Score = 42.7 bits (99), Expect = 5e-04
Identities = 29/105 (27%), Positives = 58/105 (55%), Gaps = 8/105 (7%)
Query: 30 VVIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQQPCYLLY--RLDSQNAQGFEWLFLA 87
+V E +++++G VG D + + +L + Y LY +++ ++ E +F
Sbjct: 48 IVEEGKEILVG----DVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFL 103
Query: 88 WSPDNSPVRLKMLYAATRATVKKEFGGGHIKDELFGTVKDDLSFA 132
W+P+ +P++ KM+YA+++ +KK+F G IK E +DL+ A
Sbjct: 104 WAPELAPLKSKMIYASSKDAIKKKFQG--IKHECQANGPEDLNRA 146
>gi|5031635 cofilin 1 (non-muscle) [Homo sapiens]
Length = 166
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/109 (25%), Positives = 61/109 (55%), Gaps = 12/109 (11%)
Query: 30 VVIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQQPCYLLY--RLDSQNAQGFEWLFLA 87
++ E +++++G VG+ D + +L + Y LY +++ ++ + +F+
Sbjct: 48 ILEEGKEILVG----DVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIF 103
Query: 88 WSPDNSPVRLKMLYAATRATVKKEFGGGHIKDEL----FGTVKDDLSFA 132
W+P+++P++ KM+YA+++ +KK+ G IK EL + VKD + A
Sbjct: 104 WAPESAPLKSKMIYASSKDAIKKKLTG--IKHELQANCYEEVKDRCTLA 150
>gi|4758440 glia maturation factor, gamma [Homo sapiens]
Length = 142
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/118 (27%), Positives = 61/118 (51%), Gaps = 17/118 (14%)
Query: 201 IQMKLDLERETI----ELVHTEPTDVA-QLPSRVPRDAARYHFFLYKHTHE-GDPLESVV 254
I MK+D +R+ + E + P ++ +LP R PR + + YK+ H+ G +
Sbjct: 32 IIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPR----FVVYSYKYVHDDGRVSYPLC 87
Query: 255 FIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDGAELTAEFLYDEV 312
FI+S P C +++M+Y+ K+RL+ + E+ K EI +LT +L +++
Sbjct: 88 FIFSSP-VGCKPEQQMMYAGSKNRLVQTA------ELTKVFEIRTTDDLTEAWLQEKL 138
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 37.4 bits (85), Expect = 0.020
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)
Query: 88 WSPDNSPVRLKMLYAATRATVKKEFGGGHIKD-ELFGTVKDDLSFAGYQKHLSSCAAPAP 146
W + S +R + A R V + G H+++ E K+ L + + A
Sbjct: 828 WEREGSRLRAQSEAAEERMQVLESEGRQHLEEAERERREKEALQAELEKAVVRGKELGAR 887
Query: 147 LTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNYIQMKLD 206
L +REL+Q + + ES+HQ QGL L+ E Q A ++ ++ L
Sbjct: 888 LEHLQRELEQAALERQEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQ 947
Query: 207 LERETIEL 214
LE E +L
Sbjct: 948 LEEELFQL 955
>gi|169165465 PREDICTED: similar to Destrin (actin depolymerizing
factor) [Homo sapiens]
Length = 252
Score = 34.3 bits (77), Expect = 0.17
Identities = 17/73 (23%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 60 LLDAQQPCYLLYRLDSQNAQGFEWLFLA---WSPDNSPVRLKMLYAATRATVKKEFGGGH 116
+L + CY LY + + LF+ W+P+ P++ KM++ + + +KK+F
Sbjct: 167 MLPEKDCCYALYDASFETKKSGRVLFVCLFLWAPELPPLKSKMIFTSCKDAIKKKFQANG 226
Query: 117 IKDELFGTVKDDL 129
+D + + + L
Sbjct: 227 PEDLNWACIAEKL 239
>gi|113415024 PREDICTED: similar to destrin [Homo sapiens]
Length = 199
Score = 34.3 bits (77), Expect = 0.17
Identities = 17/73 (23%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 60 LLDAQQPCYLLYRLDSQNAQGFEWLFLA---WSPDNSPVRLKMLYAATRATVKKEFGGGH 116
+L + CY LY + + LF+ W+P+ P++ KM++ + + +KK+F
Sbjct: 114 MLPEKDCCYALYDASFETKKSGRVLFVCLFLWAPELPPLKSKMIFTSCKDAIKKKFQANG 173
Query: 117 IKDELFGTVKDDL 129
+D + + + L
Sbjct: 174 PEDLNWACIAEKL 186
>gi|169165083 PREDICTED: similar to Destrin (actin depolymerizing
factor) [Homo sapiens]
Length = 252
Score = 34.3 bits (77), Expect = 0.17
Identities = 17/73 (23%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 60 LLDAQQPCYLLYRLDSQNAQGFEWLFLA---WSPDNSPVRLKMLYAATRATVKKEFGGGH 116
+L + CY LY + + LF+ W+P+ P++ KM++ + + +KK+F
Sbjct: 167 MLPEKDCCYALYDASFETKKSGRVLFVCLFLWAPELPPLKSKMIFTSCKDAIKKKFQANG 226
Query: 117 IKDELFGTVKDDL 129
+D + + + L
Sbjct: 227 PEDLNWACIAEKL 239
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 33.9 bits (76), Expect = 0.22
Identities = 42/190 (22%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 132 AGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQ 191
A Q+ + A + ++++ R+ ++ +IS S+ L G + + Q A+Q
Sbjct: 336 AQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSE---LLGTYEKAKQKDQLAIQ 392
Query: 192 QLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFLYKHTHEGDPLE 251
+LK+++ ++LDLE +T+ L + SR P D+ G+ E
Sbjct: 393 KLKERI-----LQLDLENKTLALAAS---------SRSPLDS------------HGE--E 424
Query: 252 SVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAKKIEIGDGAELTAEFLYDE 311
S + + + +K + ++ KS++ VE+ LEI E DG + TA + E
Sbjct: 425 SSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQE 484
Query: 312 VHPKQHAFKQ 321
+ + F++
Sbjct: 485 LKQLKEEFER 494
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 32.0 bits (71), Expect = 0.85
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Query: 150 AERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNYIQMKLDLER 209
+E+EL+Q R E++ + +E + + Q L LQ E Q+ QQL+Q+ Q ++ LE
Sbjct: 331 SEQELEQQR-QELERQQELERQQEQRQ-LQLKLQEELQQLEQQLEQQQQQLEQQEVQLEL 388
Query: 210 ETIEL 214
+EL
Sbjct: 389 TPVEL 393
>gi|134152674 rabaptin, RAB GTPase binding effector protein 1
isoform 2 [Homo sapiens]
Length = 829
Score = 32.0 bits (71), Expect = 0.85
Identities = 52/253 (20%), Positives = 101/253 (39%), Gaps = 41/253 (16%)
Query: 11 EELKEFFAKARAGSVRLIKVVI---EDEQLVLGASQEPVGRWDQDYDRAVLPLLDA-QQP 66
+EL++F ++ S I ++ + +++L Q+ + + +D + L+ + +Q
Sbjct: 579 QELEDFIKQSSEDSSHQISALVLRAQASEILLEELQQGLSQAKRDVQEQMAVLMQSREQV 638
Query: 67 CYLLYRL--DSQNAQGFEWLFLAWS-------PDNSPVRLKMLYAATRATVKKEFGGGHI 117
L RL D+ + QG L ++ PD + +++ + H+
Sbjct: 639 SEELVRLQKDNDSLQGKHSLHVSLQQAEDFILPDTTEALRELVLKYREDIINVRTAADHV 698
Query: 118 KDELFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIR-----INEVKTE---ISVE 169
+++L K ++ F Q C + + E++ + I+ +K E I VE
Sbjct: 699 EEKL----KAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIASISSLKAELERIKVE 754
Query: 170 SKHQTLQGLAFPLQPEAQRA----------------LQQLKQKMVNYIQMKLDLERETIE 213
T++ L F + +AQR L Q Q + I+ LER
Sbjct: 755 KGQATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAI 814
Query: 214 LVHTEPTDVAQLP 226
L T+ TD+ QLP
Sbjct: 815 LNDTKLTDINQLP 827
>gi|221219026 pleckstrin homology-like domain, family B, member 1
isoform b [Homo sapiens]
Length = 1319
Score = 31.6 bits (70), Expect = 1.1
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 153 ELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNYIQMKL 205
E ++R+ E++ ++ ++ ++ + EA+RAL Q +QK V+ +Q KL
Sbjct: 728 EQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 31.6 bits (70), Expect = 1.1
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 153 ELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNYIQMKL 205
E ++R+ E++ ++ ++ ++ + EA+RAL Q +QK V+ +Q KL
Sbjct: 728 EQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 31.6 bits (70), Expect = 1.1
Identities = 15/53 (28%), Positives = 31/53 (58%)
Query: 153 ELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNYIQMKL 205
E ++R+ E++ ++ ++ ++ + EA+RAL Q +QK V+ +Q KL
Sbjct: 728 EQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
>gi|219555649 dullard homolog [Homo sapiens]
Length = 244
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 15/128 (11%)
Query: 162 VKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVH----- 216
++ +I ++QT++ PL P ++ L Q+K+K+ + LDL+ I H
Sbjct: 28 LRRQIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKI-----LVLDLDETLIHSHHDGVLR 82
Query: 217 --TEPTDVAQLPSRVPRDAARYHFFLYKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSS 274
P +V D FF++K H LE V Y + + S++ +Y S
Sbjct: 83 PTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASME---IYGS 139
Query: 275 CKSRLLDS 282
+ LD+
Sbjct: 140 AVADKLDN 147
>gi|31542547 dullard homolog [Homo sapiens]
Length = 244
Score = 31.2 bits (69), Expect = 1.4
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 15/128 (11%)
Query: 162 VKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVH----- 216
++ +I ++QT++ PL P ++ L Q+K+K+ + LDL+ I H
Sbjct: 28 LRRQIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKI-----LVLDLDETLIHSHHDGVLR 82
Query: 217 --TEPTDVAQLPSRVPRDAARYHFFLYKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSS 274
P +V D FF++K H LE V Y + + S++ +Y S
Sbjct: 83 PTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASME---IYGS 139
Query: 275 CKSRLLDS 282
+ LD+
Sbjct: 140 AVADKLDN 147
>gi|4758616 jun oncogene [Homo sapiens]
Length = 331
Score = 30.8 bits (68), Expect = 1.9
Identities = 14/54 (25%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Query: 177 GLAFPLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVP 230
GLAFP QP+ Q Q+ +++ ++ ++ ++ + EP V ++P P
Sbjct: 194 GLAFPAQPQQQ-------QQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETP 240
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 30.8 bits (68), Expect = 1.9
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 135 QKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLK 194
Q SC P P+T ELQQ+R + + ++ + +Q + + + QQL
Sbjct: 575 QLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQL- 633
Query: 195 QKMVNYIQMKLDLERETI 212
K+ ++ +L +E++
Sbjct: 634 SKVAQQLEQELQQTQESL 651
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 30.8 bits (68), Expect = 1.9
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 135 QKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLK 194
Q SC P P+T ELQQ+R + + ++ + +Q + + + QQL
Sbjct: 539 QLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQL- 597
Query: 195 QKMVNYIQMKLDLERETI 212
K+ ++ +L +E++
Sbjct: 598 SKVAQQLEQELQQTQESL 615
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 30.8 bits (68), Expect = 1.9
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 135 QKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLK 194
Q SC P P+T ELQQ+R + + ++ + +Q + + + QQL
Sbjct: 486 QLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQL- 544
Query: 195 QKMVNYIQMKLDLERETI 212
K+ ++ +L +E++
Sbjct: 545 SKVAQQLEQELQQTQESL 562
>gi|22748757 truncated type I keratin KA21 [Homo sapiens]
Length = 295
Score = 30.4 bits (67), Expect = 2.5
Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
Query: 147 LTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLK--QKMVNYIQMK 204
L +A+ EL++ R ++ +ES H +GL L Q QL+ + ++ ++ +
Sbjct: 48 LKAAQAELKEARRQWHHLQVEIESLHAVERGLENSLHASEQHYQMQLQDLETVIEGLEKE 107
Query: 205 LDLERETIELVHTEPTDVAQLPSRVPRDAARYHFFLYK 242
L R IE E + R+ ++ A Y L K
Sbjct: 108 LQEVRRGIEKQLQEHEMLLNTKMRLEQEIATYRHLLEK 145
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 30.0 bits (66), Expect = 3.2
Identities = 21/76 (27%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Query: 147 LTSAERELQQIRINEVKTE-ISVESKHQTLQGLAFPLQPEAQRALQQLK---QKMVNYIQ 202
L S EL+Q + +TE I+V++++ + PL P+ ++ LQQ ++ V ++
Sbjct: 1379 LESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLE 1438
Query: 203 MKLDLERETIELVHTE 218
L+ + +T+E+V T+
Sbjct: 1439 DTLEEDIKTMEMVKTK 1454
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 30.0 bits (66), Expect = 3.2
Identities = 21/76 (27%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Query: 147 LTSAERELQQIRINEVKTE-ISVESKHQTLQGLAFPLQPEAQRALQQLK---QKMVNYIQ 202
L S EL+Q + +TE I+V++++ + PL P+ ++ LQQ ++ V ++
Sbjct: 1372 LESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLE 1431
Query: 203 MKLDLERETIELVHTE 218
L+ + +T+E+V T+
Sbjct: 1432 DTLEEDIKTMEMVKTK 1447
>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 29.6 bits (65), Expect = 4.2
Identities = 24/96 (25%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
Query: 150 AERELQQIRINEVKTEIS---VESKHQTLQGLAFPLQPEAQRALQ---QLKQKMVNYIQM 203
AE+E+Q+I+ ++TE +E K + LA + E++R + QLKQ + +
Sbjct: 322 AEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREA 381
Query: 204 KLDLERETIELVHTEPT--DVAQLPSRVPRDAARYH 237
+ +++ +E+ T+PT + +P+ +P D ++
Sbjct: 382 ERRAKQKLLEIA-TKPTYPPMNPIPAPLPPDIPSFN 416
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 29.6 bits (65), Expect = 4.2
Identities = 24/96 (25%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
Query: 150 AERELQQIRINEVKTEIS---VESKHQTLQGLAFPLQPEAQRALQ---QLKQKMVNYIQM 203
AE+E+Q+I+ ++TE +E K + LA + E++R + QLKQ + +
Sbjct: 405 AEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREA 464
Query: 204 KLDLERETIELVHTEPT--DVAQLPSRVPRDAARYH 237
+ +++ +E+ T+PT + +P+ +P D ++
Sbjct: 465 ERRAKQKLLEIA-TKPTYPPMNPIPAPLPPDIPSFN 499
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 29.6 bits (65), Expect = 4.2
Identities = 24/96 (25%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
Query: 150 AERELQQIRINEVKTEIS---VESKHQTLQGLAFPLQPEAQRALQ---QLKQKMVNYIQM 203
AE+E+Q+I+ ++TE +E K + LA + E++R + QLKQ + +
Sbjct: 405 AEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREA 464
Query: 204 KLDLERETIELVHTEPT--DVAQLPSRVPRDAARYH 237
+ +++ +E+ T+PT + +P+ +P D ++
Sbjct: 465 ERRAKQKLLEIA-TKPTYPPMNPIPAPLPPDIPSFN 499
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,916,635
Number of Sequences: 37866
Number of extensions: 619370
Number of successful extensions: 2057
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2031
Number of HSP's gapped (non-prelim): 57
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.