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Search of human proteins with 6005743
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1
[Homo sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H... 945 0.0
gi|8922886 DDX19-like protein [Homo sapiens] 914 0.0
gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [... 868 0.0
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [... 737 0.0
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap... 620 e-178
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 272 6e-73
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 270 2e-72
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 253 3e-67
gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 211 1e-54
gi|18375623 HLA-B associated transcript 1 [Homo sapiens] 211 1e-54
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 208 1e-53
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 203 3e-52
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi... 197 2e-50
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 167 2e-41
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 160 2e-39
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 154 1e-37
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 154 1e-37
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 154 1e-37
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 152 5e-37
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 152 5e-37
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 148 1e-35
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 145 8e-35
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens] 144 2e-34
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 140 3e-33
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 139 4e-33
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 139 6e-33
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 139 6e-33
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 139 6e-33
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 139 7e-33
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 139 7e-33
>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
sapiens]
Length = 479
Score = 945 bits (2443), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS
Sbjct: 1 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
Query: 61 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 120
LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE
Sbjct: 61 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 120
Query: 121 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 180
NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK
Sbjct: 121 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 180
Query: 181 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 240
VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV
Sbjct: 181 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 240
Query: 241 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300
LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE
Sbjct: 241 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300
Query: 301 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 360
EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV
Sbjct: 301 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 360
Query: 361 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 420
ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN
Sbjct: 361 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 420
Query: 421 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 479
ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 421 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 479
>gi|8922886 DDX19-like protein [Homo sapiens]
Length = 478
Score = 914 bits (2361), Expect = 0.0
Identities = 460/479 (96%), Positives = 473/479 (98%), Gaps = 1/479 (0%)
Query: 1 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
MATDSWALAVDEQEAA +S++NL +KEEK+K DTNG ++KT+ AEKTDEEEKEDRAAQS
Sbjct: 1 MATDSWALAVDEQEAAVKSMTNLQIKEEKVKADTNG-IIKTSTTAEKTDEEEKEDRAAQS 59
Query: 61 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 120
LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE
Sbjct: 60 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 119
Query: 121 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 180
NALP+MLAEPPQNLIAQSQSGTGKTAAFVLAMLS+VEP+++YPQCLCLSPTYELALQTGK
Sbjct: 120 NALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPSDRYPQCLCLSPTYELALQTGK 179
Query: 181 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 240
VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV
Sbjct: 180 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 239
Query: 241 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300
LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE
Sbjct: 240 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 299
Query: 301 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 360
EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV
Sbjct: 300 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 359
Query: 361 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 420
ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN
Sbjct: 360 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 419
Query: 421 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 479
ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 420 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 478
>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
[Homo sapiens]
Length = 448
Score = 868 bits (2242), Expect = 0.0
Identities = 448/479 (93%), Positives = 448/479 (93%), Gaps = 31/479 (6%)
Query: 1 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS
Sbjct: 1 MATDSWALAVDEQEAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQS 60
Query: 61 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQE 120
LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL
Sbjct: 61 LLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL--------------------- 99
Query: 121 NALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 180
PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK
Sbjct: 100 ----------PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGK 149
Query: 181 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 240
VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV
Sbjct: 150 VIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFV 209
Query: 241 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300
LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE
Sbjct: 210 LDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 269
Query: 301 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 360
EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV
Sbjct: 270 EETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 329
Query: 361 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 420
ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN
Sbjct: 330 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDN 389
Query: 421 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 479
ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
Sbjct: 390 ETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN 448
>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
[Homo sapiens]
Length = 370
Score = 737 bits (1902), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 110 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 169
MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS
Sbjct: 1 MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60
Query: 170 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 229
PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK
Sbjct: 61 PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 120
Query: 230 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 289
FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV
Sbjct: 121 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 180
Query: 290 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 349
PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL
Sbjct: 181 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 240
Query: 350 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 409
AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD
Sbjct: 241 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 300
Query: 410 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 469
LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD
Sbjct: 301 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 360
Query: 470 DLDEIEKIAN 479
DLDEIEKIAN
Sbjct: 361 DLDEIEKIAN 370
>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
sapiens]
Length = 483
Score = 620 bits (1600), Expect = e-178
Identities = 298/434 (68%), Positives = 371/434 (85%), Gaps = 1/434 (0%)
Query: 44 NAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQL 103
N + DEE+ D AA SLLNKLI +LV+++++VEVLQ+DP+SPLYSVK+FEELRLK +L
Sbjct: 49 NINEDDEEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEEL 108
Query: 104 LQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYP 163
L+G+YAMGFNRPSKIQE ALP+MLA PPQNLIAQSQSGTGKTAAFVLAMLS+V +P
Sbjct: 109 LKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFP 168
Query: 164 QCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLD 223
QCLCL+PTYELALQTG+V+EQMGKF ++++ YA+RGN++ RG I++QI+IGTPGTVLD
Sbjct: 169 QCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLD 228
Query: 224 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 283
WC KLK ID KI+VFVLDEADVMI TQG D SIRIQR LP CQMLLFSATFEDSVW
Sbjct: 229 WCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWH 288
Query: 284 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 343
FA++++PDPNVIKL++EE TL+ I+QYYVLC R +K+QALCN+YG+ITI QA+IFC TR
Sbjct: 289 FAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTR 348
Query: 344 KTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS 403
+ A WL E+ ++GHQV+LLSGE+ VEQRA++I+RFR+GKEKVL+TTNVCARGIDV+QV+
Sbjct: 349 RNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVT 408
Query: 404 VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKI 463
+V+NFDLPV + PD ETYLHRIGRTGRFGK+GLA NM++ +++ +IQ+HFN I
Sbjct: 409 IVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLM-KIQDHFNSSI 467
Query: 464 ERLDTDDLDEIEKI 477
++L+ +D+DEIEKI
Sbjct: 468 KQLNAEDMDEIEKI 481
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 272 bits (695), Expect = 6e-73
Identities = 157/389 (40%), Positives = 241/389 (61%), Gaps = 18/389 (4%)
Query: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 150
V +F+++ LK LL+G+YA GF +PS IQ+ A+ + ++IAQ+QSGTGKTA F +
Sbjct: 32 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKG--YDVIAQAQSGTGKTATFAI 89
Query: 151 AMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-----NKLER 205
++L Q+E K Q L L+PT ELA Q KVI +G + +A G N++++
Sbjct: 90 SILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGAT--CHACIGGTNVRNEMQK 147
Query: 206 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 265
Q + IV+GTPG V D ++ +++ PK IK+FVLDEAD M++ +G +DQ I + L
Sbjct: 148 LQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEMLS-RGFKDQIYEIFQKLN 205
Query: 266 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 325
+ Q++L SAT V + +K + DP I +K+EE TL+ IKQ+Y+ + K LC
Sbjct: 206 TSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLC 265
Query: 326 NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 385
+LY +TI QA+IF +TR+ WL ++ V+ L G+M ++R ++ FR G +
Sbjct: 266 DLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSR 325
Query: 386 VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 445
VL+TT++ ARGIDV+QVS+VIN+DLP ++ E Y+HRIGR GRFG++G+A+N V +
Sbjct: 326 VLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINFV-T 378
Query: 446 KHSMNILNRIQEHFNKKIERLDTDDLDEI 474
+ IL I+ +N +E + + D I
Sbjct: 379 EEDKRILRDIETFYNTTVEEMPMNVADLI 407
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 270 bits (691), Expect = 2e-72
Identities = 157/388 (40%), Positives = 237/388 (61%), Gaps = 16/388 (4%)
Query: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENA-LPLMLAEPPQNLIAQSQSGTGKTAAFV 149
V SF+++ L LL+G+YA GF +PS IQ+ A LP + ++IAQ+QSGTGKTA F
Sbjct: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG---YDVIAQAQSGTGKTATFA 87
Query: 150 LAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKI 209
+++L Q+E K Q L L+PT ELA Q KV+ +G + A N QK+
Sbjct: 88 ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL 147
Query: 210 SEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPR 266
+ I++GTPG V D ++ +++ PK IK+FVLDEAD M++ +G +DQ I + L
Sbjct: 148 QMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLS-RGFKDQIYDIFQKLNS 205
Query: 267 NCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCN 326
N Q++L SAT V + +K + DP I +K+EE TL+ I+Q+Y+ + K LC+
Sbjct: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
Query: 327 LYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKV 386
LY +TI QA+IF +TR+ WL ++ V+ + G+M ++R ++ FR G +V
Sbjct: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV 325
Query: 387 LVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSK 446
L+TT++ ARGIDV+QVS+VIN+DLP ++ E Y+HRIGR GRFG++G+A+NMV ++
Sbjct: 326 LITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINMV-TE 378
Query: 447 HSMNILNRIQEHFNKKIERLDTDDLDEI 474
L I+ +N IE + + D I
Sbjct: 379 EDKRTLRDIETFYNTSIEEMPLNVADLI 406
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 253 bits (646), Expect = 3e-67
Identities = 144/389 (37%), Positives = 239/389 (61%), Gaps = 23/389 (5%)
Query: 93 SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 152
+F+ + L+ LL+G+YA GF +PS IQ+ A+ ++ +++IAQSQSGTGKTA F +++
Sbjct: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISV 96
Query: 153 LSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLER 205
L ++ + Q L L+PT ELA+Q K + +G Y ++ + G KL+
Sbjct: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDY 155
Query: 206 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 265
GQ +V GTPG V D + + + + IK+ VLDEAD M+ +G ++Q + R LP
Sbjct: 156 GQ----HVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLP 209
Query: 266 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 325
Q++L SAT + + K + DP I +KR+E TL+ IKQ++V + KF LC
Sbjct: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC 269
Query: 326 NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 385
+LY +TI QA+IFC+T++ WL ++ + V+ + G+M ++R ++++ FR G +
Sbjct: 270 DLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASR 329
Query: 386 VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 445
VL++T+V ARG+DV QVS++IN+DLP ++ E Y+HRIGR+GR+G++G+A+N V
Sbjct: 330 VLISTDVWARGLDVPQVSLIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFV-K 382
Query: 446 KHSMNILNRIQEHFNKKIERLDTDDLDEI 474
+ IL I+++++ +I+ + + D I
Sbjct: 383 NDDIRILRDIEQYYSTQIDEMPMNVADLI 411
>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 211 bits (537), Expect = 1e-54
Identities = 131/399 (32%), Positives = 216/399 (54%), Gaps = 18/399 (4%)
Query: 81 QRDPNSPLYSVKS--FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQS 138
++D S+ S F + LKP+LL+ + GF PS++Q +P + +++ Q+
Sbjct: 32 KKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILG--MDVLCQA 89
Query: 139 QSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAV 198
+SG GKTA FVLA L Q+EP L + T ELA Q K E+ K+ P +K+A
Sbjct: 90 KSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFF 149
Query: 199 RGNKLERGQKISEQ----IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQ 254
G +++ +++ ++ IV+GTPG +L ++ K ++ K IK F+LDE D M+ +
Sbjct: 150 GGLSIKKDEEVLKKNCPHIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQLDMR 208
Query: 255 DQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TLDTIKQYYVL 313
I RM P Q+++FSAT + +K + DP I + E + TL ++QYYV
Sbjct: 209 RDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVK 268
Query: 314 CSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRA 373
+EK + L +L + Q +IF + + LA L ++ + M E+R
Sbjct: 269 LKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL 327
Query: 374 AVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRF 433
+ ++F++ + ++LV TN+ RG+D+E+V++ N+D+P D D TYLHR+ R GRF
Sbjct: 328 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSD------TYLHRVARAGRF 381
Query: 434 GKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLD 472
G +GLA+ V ++ ILN +Q+ F I L D++D
Sbjct: 382 GTKGLAITFVSDENDAKILNDVQDRFEVNISEL-PDEID 419
>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 211 bits (537), Expect = 1e-54
Identities = 131/399 (32%), Positives = 216/399 (54%), Gaps = 18/399 (4%)
Query: 81 QRDPNSPLYSVKS--FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQS 138
++D S+ S F + LKP+LL+ + GF PS++Q +P + +++ Q+
Sbjct: 32 KKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILG--MDVLCQA 89
Query: 139 QSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAV 198
+SG GKTA FVLA L Q+EP L + T ELA Q K E+ K+ P +K+A
Sbjct: 90 KSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFF 149
Query: 199 RGNKLERGQKISEQ----IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQ 254
G +++ +++ ++ IV+GTPG +L ++ K ++ K IK F+LDE D M+ +
Sbjct: 150 GGLSIKKDEEVLKKNCPHIVVGTPGRILA-LARNKSLNLKHIKHFILDECDKMLEQLDMR 208
Query: 255 DQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TLDTIKQYYVL 313
I RM P Q+++FSAT + +K + DP I + E + TL ++QYYV
Sbjct: 209 RDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVK 268
Query: 314 CSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRA 373
+EK + L +L + Q +IF + + LA L ++ + M E+R
Sbjct: 269 LKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL 327
Query: 374 AVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRF 433
+ ++F++ + ++LV TN+ RG+D+E+V++ N+D+P D D TYLHR+ R GRF
Sbjct: 328 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSD------TYLHRVARAGRF 381
Query: 434 GKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLD 472
G +GLA+ V ++ ILN +Q+ F I L D++D
Sbjct: 382 GTKGLAITFVSDENDAKILNDVQDRFEVNISEL-PDEID 419
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 208 bits (529), Expect = 1e-53
Identities = 123/378 (32%), Positives = 202/378 (53%), Gaps = 15/378 (3%)
Query: 94 FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML 153
F + LKP+LL+ + GF PS++Q +P + +++ Q++SG GKTA FVLA L
Sbjct: 46 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILG--MDVLCQAKSGMGKTAVFVLATL 103
Query: 154 SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ- 212
Q+EP N L + T ELA Q K E+ K+ P +K++ G +++ +++ ++
Sbjct: 104 QQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKN 163
Query: 213 ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQ 269
+V+GTPG +L F K +K FVLDE D M+ + I R+ P Q
Sbjct: 164 CPHVVVGTPGRILALVRNRSF-SLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQ 222
Query: 270 MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE-TLDTIKQYYVLCSSRDEKFQALCNLY 328
++FSAT + +K + DP + + E + TL ++QYYV EK + L +L
Sbjct: 223 CMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKD-SEKNRKLFDLL 281
Query: 329 GAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLV 388
+ Q +IF + + LA L ++ + M E+R + ++F++ + ++LV
Sbjct: 282 DVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILV 341
Query: 389 TTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHS 448
TN+ RG+D+E+V++V N+D+P D D TYLHR+ R GRFG +GLA+ V ++
Sbjct: 342 ATNLFGRGMDIERVNIVFNYDMPEDSD------TYLHRVARAGRFGTKGLAITFVSDEND 395
Query: 449 MNILNRIQEHFNKKIERL 466
ILN +Q+ F + L
Sbjct: 396 AKILNDVQDRFEVNVAEL 413
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 203 bits (516), Expect = 3e-52
Identities = 134/380 (35%), Positives = 215/380 (56%), Gaps = 18/380 (4%)
Query: 94 FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML 153
FE+ LK +LL G++ MG+ +PS IQE ++P+ L+ ++++A++++GTGK+ A+++ +L
Sbjct: 98 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSG--RDILARAKNGTGKSGAYLIPLL 155
Query: 154 SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG-QKISE- 211
+++ Q + + PT ELALQ ++ Q+ K K+ G L ++ +
Sbjct: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDT 215
Query: 212 -QIVIGTPGTVLDWCSK-LKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQ 269
+VI TPG +LD K + +D +++ VLDEAD +++ Q I LP+N Q
Sbjct: 216 VHVVIATPGRILDLIKKGVAKVD--HVQMIVLDEADKLLSQDFVQIME-DIILTLPKNRQ 272
Query: 270 MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYG 329
+LL+SATF SV KF + P I L EE TL + QYY + R +K L L+
Sbjct: 273 ILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVTER-QKVHCLNTLFS 330
Query: 330 AITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVT 389
+ I Q++IFC++ + LA ++S+ G+ + +M E R V FR G + LV
Sbjct: 331 RLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVC 390
Query: 390 TNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSM 449
T++ RGID++ V+VVINFD P ETYLHRIGR+GRFG GLA+N++
Sbjct: 391 TDLFTRGIDIQAVNVVINFDFP------KLAETYLHRIGRSGRFGHLGLAINLITYDDRF 444
Query: 450 NILNRIQEHFNKKIERLDTD 469
N L I+E +I+ + ++
Sbjct: 445 N-LKSIEEQLGTEIKPIPSN 463
>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
sapiens]
Length = 824
Score = 197 bits (500), Expect = 2e-50
Identities = 129/376 (34%), Positives = 199/376 (52%), Gaps = 18/376 (4%)
Query: 94 FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML 153
FE L L +L+G+ A GF RPS +Q A+PL +LI Q++SGTGKT F L
Sbjct: 64 FESLLLSRPVLEGLRAAGFERPSPVQLKAIPL--GRCGLDLIVQAKSGTGKTCVFSTIAL 121
Query: 154 SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ- 212
+ N Q L L+PT E+A+Q VI +G L+ + G L + + ++
Sbjct: 122 DSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKC 181
Query: 213 -IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQML 271
I +G+PG + +L +++P I++F+LDEAD ++ Q+Q I LP + QML
Sbjct: 182 HIAVGSPGRIKQLI-ELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQML 240
Query: 272 LFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSR-------DEKFQAL 324
SAT+ + + K + DP ++L + +L +KQYY + +S +EK Q L
Sbjct: 241 AVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHL 300
Query: 325 CNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKE 384
L+ I QA++F + A LA LS +G +SG M QR + + +
Sbjct: 301 QELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHC 360
Query: 385 KVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVD 444
+VL++T++ +RGID E+V++V+N D+P+D ETY+HRIGR GRFG GL V
Sbjct: 361 RVLISTDLTSRGIDAEKVNLVVNLDVPLDW------ETYMHRIGRAGRFGTLGLTVTYCC 414
Query: 445 SKHSMNILNRIQEHFN 460
N++ RI + N
Sbjct: 415 RGEEENMMMRIAQKCN 430
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 167 bits (423), Expect = 2e-41
Identities = 112/386 (29%), Positives = 201/386 (52%), Gaps = 16/386 (4%)
Query: 92 KSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLA 151
K+F++L + L + +G+ +P+KIQ A+PL L +++I +++G+GKT AF L
Sbjct: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQG--RDIIGLAETGSGKTGAFALP 81
Query: 152 MLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-NKLERGQKIS 210
+L+ + + L L+PT ELA Q + E +G ++ A V G + + + ++
Sbjct: 82 ILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG-VQSAVIVGGIDSMSQSLALA 140
Query: 211 EQ--IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNC 268
++ I+I TPG ++D K + + +K V+DEAD I + + +I +++PR+
Sbjct: 141 KKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEAD-RILNMDFETEVDKILKVIPRDR 199
Query: 269 QMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLY 328
+ LFSAT V K + + +P + + +T++ ++QYY+ S+ K L +
Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKF-KDTYLVYIL 258
Query: 329 GAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLV 388
+ MIFC T A L G L G+M +R + +F+ +L+
Sbjct: 259 NELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILL 318
Query: 389 TTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHS 448
T+V +RG+D+ V VV+NFD+P ++ Y+HR+GRT R G+ G A+ V +++
Sbjct: 319 ATDVASRGLDIPHVDVVVNFDIPT------HSKDYIHRVGRTARAGRSGKAITFV-TQYD 371
Query: 449 MNILNRIQEHFNKKIERLDTDDLDEI 474
+ + RI+ KK+ T D DE+
Sbjct: 372 VELFQRIEHLIGKKLPGFPTQD-DEV 396
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 160 bits (406), Expect = 2e-39
Identities = 130/440 (29%), Positives = 214/440 (48%), Gaps = 33/440 (7%)
Query: 26 KEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQR--- 82
K EK K G+ K + ++ DEE ED A+++ + N++ + ++V R
Sbjct: 139 KLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSA-DENILTKADTLKVKDRKKK 197
Query: 83 -----------DPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPP 131
+ S SF+++ L LL+ + AMGF +P+ IQ+ +P+ L
Sbjct: 198 KKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLG-- 255
Query: 132 QNLIAQSQSGTGKTAAFVLAMLSQV--EPANK-YPQCLCLSPTYELALQTGKVIEQMGKF 188
+++ A + +GTGKTAAF L +L ++ +P + L L PT EL +Q V Q+ +F
Sbjct: 256 KDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQF 315
Query: 189 YPELKLAYAVRG---NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEAD 245
+ AV G E + + I+I TPG ++D I+V +LDEAD
Sbjct: 316 C-NITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEAD 374
Query: 246 VMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLD 305
M+ + ++Q I RM + Q +LFSAT D V A + +P I + +
Sbjct: 375 RML-DEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAP 433
Query: 306 TIKQYYV-LCSSRDEKFQALCNLYGAITIAQ-AMIFCHTRKTASWLAAELSKEGHQVALL 363
++Q ++ + +R+ +A+ T M+F T+K A + L G QV L
Sbjct: 434 FLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGEL 493
Query: 364 SGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETY 423
G + QR + RF++ + +LV T+V ARG+D+E V VINF +P + Y
Sbjct: 494 HGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMP------NTIKHY 547
Query: 424 LHRIGRTGRFGKRGLAVNMV 443
+HR+GRT R G+ G +V++V
Sbjct: 548 VHRVGRTARAGRAGRSVSLV 567
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 154 bits (390), Expect = 1e-37
Identities = 126/435 (28%), Positives = 210/435 (48%), Gaps = 47/435 (10%)
Query: 46 EKTDEEE------KEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL 99
+K+DE++ +R Q L + + + + V N P + ++SF ++ +
Sbjct: 129 DKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPH-IESFSDVEM 187
Query: 100 KPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEP- 158
++ + + RP+ +Q++A+P++ + ++L+A +Q+G+GKTAAF+L +LSQ+
Sbjct: 188 GEIIMGNIELTRYTRPTPVQKHAIPII--KEKRDLMACAQTGSGKTAAFLLPILSQIYSD 245
Query: 159 -----------------ANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN 201
+YP L L+PT ELA+Q + E+ KF ++ V
Sbjct: 246 GPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRSRVRPCVVYG 302
Query: 202 KLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQ 256
+ GQ+I + +++ TPG ++D + K I K VLDEAD M+ G + Q
Sbjct: 303 GADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRML-DMGFEPQ 360
Query: 257 SIRI---QRMLPRNCQ-MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYV 312
RI M P+ + ++FSATF + A+ + + + + R T + I Q V
Sbjct: 361 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420
Query: 313 LCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQR 372
D++ L L + ++F T+K A L L EG+ + G+ R
Sbjct: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480
Query: 373 AAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGR 432
+ +FR GK +LV T V ARG+D+ V VINFDLP D E Y+HRIGRTGR
Sbjct: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLP------SDIEEYVHRIGRTGR 534
Query: 433 FGKRGLAVNMVDSKH 447
G GLA + + ++
Sbjct: 535 VGNLGLATSFFNERN 549
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 154 bits (390), Expect = 1e-37
Identities = 120/388 (30%), Positives = 195/388 (50%), Gaps = 41/388 (10%)
Query: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 150
+++F ++ + ++ + + RP+ +Q++A+P++ + ++L+A +Q+G+GKTAAF+L
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGK--RDLMACAQTGSGKTAAFLL 234
Query: 151 AMLSQVEP------------------ANKYPQCLCLSPTYELALQTGKVIEQMGKFYPEL 192
+LSQ+ +YP L L+PT ELA+Q + E+ KF
Sbjct: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRS 291
Query: 193 KLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVM 247
++ V + GQ+I + +++ TPG ++D + K I K VLDEAD M
Sbjct: 292 RVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRM 350
Query: 248 IATQGHQDQSIRI---QRMLPRNCQ-MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEET 303
+ G + Q RI M P+ + ++FSATF + A+ + + + + R T
Sbjct: 351 L-DMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGST 409
Query: 304 LDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALL 363
+ I Q V D++ L L + + ++F T+K A L L EG+ +
Sbjct: 410 SENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSI 469
Query: 364 SGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETY 423
G+ R + +FR GK +LV T V ARG+D+ V VINFDLP D E Y
Sbjct: 470 HGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLP------SDIEEY 523
Query: 424 LHRIGRTGRFGKRGLAVNMVDSKHSMNI 451
+HRIGRTGR G GLA + + K +MNI
Sbjct: 524 VHRIGRTGRVGNLGLATSFFNEK-NMNI 550
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 154 bits (390), Expect = 1e-37
Identities = 120/388 (30%), Positives = 195/388 (50%), Gaps = 41/388 (10%)
Query: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 150
+++F ++ + ++ + + RP+ +Q++A+P++ + ++L+A +Q+G+GKTAAF+L
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGK--RDLMACAQTGSGKTAAFLL 234
Query: 151 AMLSQVEP------------------ANKYPQCLCLSPTYELALQTGKVIEQMGKFYPEL 192
+LSQ+ +YP L L+PT ELA+Q + E+ KF
Sbjct: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRS 291
Query: 193 KLAYAVRGNKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVM 247
++ V + GQ+I + +++ TPG ++D + K I K VLDEAD M
Sbjct: 292 RVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDEADRM 350
Query: 248 IATQGHQDQSIRI---QRMLPRNCQ-MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEET 303
+ G + Q RI M P+ + ++FSATF + A+ + + + + R T
Sbjct: 351 L-DMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGST 409
Query: 304 LDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALL 363
+ I Q V D++ L L + + ++F T+K A L L EG+ +
Sbjct: 410 SENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSI 469
Query: 364 SGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETY 423
G+ R + +FR GK +LV T V ARG+D+ V VINFDLP D E Y
Sbjct: 470 HGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLP------SDIEEY 523
Query: 424 LHRIGRTGRFGKRGLAVNMVDSKHSMNI 451
+HRIGRTGR G GLA + + K +MNI
Sbjct: 524 VHRIGRTGRVGNLGLATSFFNEK-NMNI 550
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 152 bits (385), Expect = 5e-37
Identities = 115/365 (31%), Positives = 186/365 (50%), Gaps = 20/365 (5%)
Query: 93 SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 152
SF QL+ + + +P+ IQ +P+ L+ +++I +++G+GKTAAF+ M
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSG--RDMIGIAKTGSGKTAAFIWPM 311
Query: 153 L------SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 206
L ++EP + P + + PT EL Q ++ GK Y +A G+ E+
Sbjct: 312 LIHIMDQKELEPGDG-PIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQA 370
Query: 207 QKISE--QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 264
+ + E +IV+ TPG ++D K K + +++ V DEAD M G + Q I +
Sbjct: 371 KALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMF-DMGFEYQVRSIASHV 428
Query: 265 PRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQAL 324
+ Q LLFSATF + K A+ ++ DP + E + + Q + S K+ L
Sbjct: 429 RPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWL 488
Query: 325 CNLYGAITIAQAMIFCHTRKT-ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGK 383
T + +++ T+K A LA L +EGH + LL G+M +R VI F++
Sbjct: 489 TRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKD 548
Query: 384 EKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV 443
VLV T+V ARG+D+ + VIN+D+ D D T+ HRIGRTGR G++G+A ++
Sbjct: 549 IPVLVATDVAARGLDIPSIKTVINYDVARDID------THTHRIGRTGRAGEKGVAYTLL 602
Query: 444 DSKHS 448
K S
Sbjct: 603 TPKDS 607
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 152 bits (385), Expect = 5e-37
Identities = 115/365 (31%), Positives = 186/365 (50%), Gaps = 20/365 (5%)
Query: 93 SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 152
SF QL+ + + +P+ IQ +P+ L+ +++I +++G+GKTAAF+ M
Sbjct: 254 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSG--RDMIGIAKTGSGKTAAFIWPM 311
Query: 153 L------SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG 206
L ++EP + P + + PT EL Q ++ GK Y +A G+ E+
Sbjct: 312 LIHIMDQKELEPGDG-PIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQA 370
Query: 207 QKISE--QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML 264
+ + E +IV+ TPG ++D K K + +++ V DEAD M G + Q I +
Sbjct: 371 KALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMF-DMGFEYQVRSIASHV 428
Query: 265 PRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQAL 324
+ Q LLFSATF + K A+ ++ DP + E + + Q + S K+ L
Sbjct: 429 RPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWL 488
Query: 325 CNLYGAITIAQAMIFCHTRKT-ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGK 383
T + +++ T+K A LA L +EGH + LL G+M +R VI F++
Sbjct: 489 TRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKD 548
Query: 384 EKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV 443
VLV T+V ARG+D+ + VIN+D+ D D T+ HRIGRTGR G++G+A ++
Sbjct: 549 IPVLVATDVAARGLDIPSIKTVINYDVARDID------THTHRIGRTGRAGEKGVAYTLL 602
Query: 444 DSKHS 448
K S
Sbjct: 603 TPKDS 607
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 148 bits (373), Expect = 1e-35
Identities = 116/394 (29%), Positives = 197/394 (50%), Gaps = 26/394 (6%)
Query: 94 FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML 153
F EL L L++ +G +P+ +Q +P +L ++ + +++G+GKTAAFVL +L
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEG--RDCLGCAKTGSGKTAAFVLPIL 61
Query: 154 SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-----NKLERGQK 208
++ CL L+PT ELA Q + +GK LK V G LE +K
Sbjct: 62 QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLG-LKDCIIVGGMDMVAQALELSRK 120
Query: 209 ISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRML---P 265
+VI TPG + D KKI+ V+DEAD ++ QG D ++ ++ +L P
Sbjct: 121 --PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLE-QGCTDFTVDLEAILAAVP 177
Query: 266 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 325
Q LLFSAT D++ + P + + T++ + Q Y+L + K L
Sbjct: 178 ARRQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEK-VKDAYLV 236
Query: 326 NLYGAITIAQA----MIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFRE 381
+L +IF +T KT L L K L M ++R A + +F+
Sbjct: 237 HLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKS 296
Query: 382 GKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVN 441
++L+ T+V +RG+D+ V VVIN + P G P + Y+HR+GRT R G++G A+
Sbjct: 297 SIYRILIATDVASRGLDIPTVQVVINHNTP----GLP--KIYIHRVGRTARAGRQGQAIT 350
Query: 442 MVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIE 475
+V +++ +++++ I+E KK+E ++ + ++
Sbjct: 351 LV-TQYDIHLVHAIEEQIKKKLEEFSVEEAEVLQ 383
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 145 bits (366), Expect = 8e-35
Identities = 129/470 (27%), Positives = 220/470 (46%), Gaps = 34/470 (7%)
Query: 14 EAAAESLSNLHLKEEKIKPDT---------NGAVVKTNANAEKTDEEEKEDRAAQSLLNK 64
E ESL+ ++ K K T GA ++ ++ E E++K R ++ K
Sbjct: 72 EKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQRESKLTSGK 131
Query: 65 LI-----RSNLVDNTNQVEVLQRDPNSPLYSVKSFE-ELRLKPQLLQGVYAMGFNRPSKI 118
L + N + N +++ V D P+ + + + E ++ +LLQ + GF P+ I
Sbjct: 132 LENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPI 191
Query: 119 QENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQV-EPANKYPQCLCLSPTYELALQ 177
Q A+P+ML + L+A + +G+GKT AF + +L Q+ +PANK + L +SPT ELA Q
Sbjct: 192 QMQAIPVMLHG--RELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQ 249
Query: 178 TGKVIEQMGK---FYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSK-LKFIDP 233
+ + ++ + F + AV K I++ TP ++ + ID
Sbjct: 250 IHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDL 309
Query: 234 KKIKVFVLDEADVMI--ATQGHQDQSIRI-QRMLPRNCQMLLFSATFEDSVWKFAQKVVP 290
++ V+DE+D + G +DQ I + +FSATF V ++ + +
Sbjct: 310 ASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLD 369
Query: 291 DPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLA 350
+ + + ++T++Q + S K A+ L ++F + + A L
Sbjct: 370 NVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELF 429
Query: 351 AELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDL 410
EL EG V ++ E +QR + FR GK VL+ T + ARGID + V++VIN+D
Sbjct: 430 HELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 489
Query: 411 PVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV---DSKHSMNILNRIQE 457
P + Y+HRIGRTGR G +G A+ D ++ N IQ+
Sbjct: 490 PT------SSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQ 533
>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
Length = 547
Score = 144 bits (362), Expect = 2e-34
Identities = 110/390 (28%), Positives = 194/390 (49%), Gaps = 49/390 (12%)
Query: 94 FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML 153
FE + L P+LLQ V +G++RP+ IQE A+PL L ++L+A++++G+GKTAA+ + ML
Sbjct: 9 FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLAL--EGKDLLARARTGSGKTAAYAIPML 66
Query: 154 SQV-------EPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP-ELKLA--YAVRGNKL 203
+ + + L L PT ELA Q +I+Q+ + ++++A A +
Sbjct: 67 QLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126
Query: 204 ERGQKISE-QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQR 262
+R + + +V+GTP +L + +++ V+DEAD++ + G +++ +
Sbjct: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSF-GFEEELKSLLC 185
Query: 263 MLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE-ETLDTIKQYYVLCSSRDEKF 321
LPR Q L SATF + V + ++ +P +KL+ + D ++Q+ V+C + ++KF
Sbjct: 186 HLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKF 245
Query: 322 QALCNLYGAITI-AQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFR 380
L L I ++++F +T + + L L + +L+GE+ + R +I +F
Sbjct: 246 LLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFN 305
Query: 381 EGKEKVLVTTNV---------------------------CARGIDVEQVSVVINFDLPVD 413
+G ++ T+ ARGID VS V+NFDLP
Sbjct: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP-- 363
Query: 414 KDGNPDNETYLHRIGRTGRFGKRGLAVNMV 443
P E Y+HR GRT R G+ + V
Sbjct: 364 ----PTPEAYIHRAGRTARANNPGIVLTFV 389
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 140 bits (353), Expect = 3e-33
Identities = 120/432 (27%), Positives = 206/432 (47%), Gaps = 25/432 (5%)
Query: 43 ANAEKTDEEEKEDRAAQSLLNKLI-----RSNLVDNTNQVEVLQRDPNSPLYSVKSFE-E 96
++ E E++K R ++ KL + N + N +++ V D P+ + + + E
Sbjct: 2 SSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQE 61
Query: 97 LRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQV 156
++ +LLQ + GF P+ IQ A+P+ML + L+A + +G+GKT AF + +L Q+
Sbjct: 62 YKINSRLLQNILDAGFQMPTPIQMQAIPVMLHG--RELLASAPTGSGKTLAFSIPILMQL 119
Query: 157 -EPANKYPQCLCLSPTYELALQTGKVIEQMGK---FYPELKLAYAVRGNKLERGQKISEQ 212
+PANK + L +SPT ELA Q + + ++ + F + AV K
Sbjct: 120 KQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD 179
Query: 213 IVIGTPGTVLDWCSK-LKFIDPKKIKVFVLDEADVMI--ATQGHQDQSIRI-QRMLPRNC 268
I++ TP ++ + ID ++ V+DE+D + G +DQ I
Sbjct: 180 ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKV 239
Query: 269 QMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLY 328
+ +FSATF V ++ + + + + + ++T++Q + S K A+ L
Sbjct: 240 RRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 299
Query: 329 GAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLV 388
++F + + A L EL EG V ++ E +QR + FR GK VL+
Sbjct: 300 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 359
Query: 389 TTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMV---DS 445
T + ARGID + V++VIN+D P + Y+HRIGRTGR G +G A+ D
Sbjct: 360 CTALLARGIDFKGVNLVINYDFPT------SSVEYIHRIGRTGRAGNKGKAITFFTEDDK 413
Query: 446 KHSMNILNRIQE 457
++ N IQ+
Sbjct: 414 PLLRSVANVIQQ 425
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 139 bits (351), Expect = 4e-33
Identities = 109/397 (27%), Positives = 191/397 (48%), Gaps = 52/397 (13%)
Query: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 150
++S+++ L P +L+ + G+ P+ IQ A+P+ L +++I +++G+GKTAAF++
Sbjct: 390 IRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQN--RDIIGVAETGSGKTAAFLI 447
Query: 151 AML---------SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN 201
+L ++E +++ P + L+PT ELA Q + + GK P AV G
Sbjct: 448 PLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGK--PLGIRTVAVIGG 505
Query: 202 KLERGQ----KISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQS 257
Q ++ +IVI TPG ++D +++ + VLDEAD MI G +
Sbjct: 506 ISREDQGFRLRMGCEIVIATPGRLIDVLEN-RYLVLSRCTYVVLDEADRMI-DMGFEPDV 563
Query: 258 IRIQRMLP--------------------------RNCQMLLFSATFEDSVWKFAQKVVPD 291
+I +P + Q ++F+AT +V + A+ +
Sbjct: 564 QKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRR 623
Query: 292 PNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAA 351
P V+ + + + ++Q L S +++ + L L +IF + +K LA
Sbjct: 624 PAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFD-PPIIIFVNQKKGCDVLAK 682
Query: 352 ELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLP 411
L K G+ L G EQR + + G + +LV T+V RGID++ VS+V+N+D+
Sbjct: 683 SLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMA 742
Query: 412 VDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHS 448
+ E Y+HRIGRTGR GK G+A+ + + S
Sbjct: 743 ------KNIEDYIHRIGRTGRAGKSGVAITFLTKEDS 773
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 139 bits (350), Expect = 6e-33
Identities = 115/372 (30%), Positives = 186/372 (50%), Gaps = 29/372 (7%)
Query: 90 SVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFV 149
++ +FEE L L + G+ + + +Q+ ++P++LA ++L+A +Q+G+GKTAAF+
Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFL 343
Query: 150 LAMLSQVE----PANKY-----PQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG 200
L +L+ + A+++ P+C+ ++PT EL Q + + KF + V
Sbjct: 344 LPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVIY 400
Query: 201 NKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQ-GHQ 254
+ G I + I+ TPG ++D K K I K+IK VLDEAD M+ G +
Sbjct: 401 GGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPE 459
Query: 255 DQSIRIQRMLP--RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYV 312
+ + +P Q L+FSATF + + + A + + + + Q V
Sbjct: 460 MKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTV 519
Query: 313 LCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQR 372
L + K + L + I + M+F T+K A ++A L +E + G+ +R
Sbjct: 520 LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQRER 579
Query: 373 AAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGR 432
+ FR GK VLV T+V ARG+D+E V VINFDLP D Y+HRIGRTGR
Sbjct: 580 EQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTID------EYVHRIGRTGR 633
Query: 433 FGKRGLAVNMVD 444
G G A++ D
Sbjct: 634 CGNTGRAISFFD 645
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 139 bits (350), Expect = 6e-33
Identities = 115/372 (30%), Positives = 186/372 (50%), Gaps = 29/372 (7%)
Query: 90 SVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFV 149
++ +FEE L L + G+ + + +Q+ ++P++LA ++L+A +Q+G+GKTAAF+
Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFL 343
Query: 150 LAMLSQVE----PANKY-----PQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG 200
L +L+ + A+++ P+C+ ++PT EL Q + + KF + V
Sbjct: 344 LPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVIY 400
Query: 201 NKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQ-GHQ 254
+ G I + I+ TPG ++D K K I K+IK VLDEAD M+ G +
Sbjct: 401 GGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPE 459
Query: 255 DQSIRIQRMLP--RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYV 312
+ + +P Q L+FSATF + + + A + + + + Q V
Sbjct: 460 MKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTV 519
Query: 313 LCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQR 372
L + K + L + I + M+F T+K A ++A L +E + G+ +R
Sbjct: 520 LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQRER 579
Query: 373 AAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGR 432
+ FR GK VLV T+V ARG+D+E V VINFDLP D Y+HRIGRTGR
Sbjct: 580 EQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTID------EYVHRIGRTGR 633
Query: 433 FGKRGLAVNMVD 444
G G A++ D
Sbjct: 634 CGNTGRAISFFD 645
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 139 bits (350), Expect = 6e-33
Identities = 115/372 (30%), Positives = 186/372 (50%), Gaps = 29/372 (7%)
Query: 90 SVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFV 149
++ +FEE L L + G+ + + +Q+ ++P++LA ++L+A +Q+G+GKTAAF+
Sbjct: 252 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFL 309
Query: 150 LAMLSQVE----PANKY-----PQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG 200
L +L+ + A+++ P+C+ ++PT EL Q + + KF + V
Sbjct: 310 LPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVIY 366
Query: 201 NKLERGQKISE-----QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQ-GHQ 254
+ G I + I+ TPG ++D K K I K+IK VLDEAD M+ G +
Sbjct: 367 GGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPE 425
Query: 255 DQSIRIQRMLP--RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYV 312
+ + +P Q L+FSATF + + + A + + + + Q V
Sbjct: 426 MKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTV 485
Query: 313 LCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQR 372
L + K + L + I + M+F T+K A ++A L +E + G+ +R
Sbjct: 486 LQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQRER 545
Query: 373 AAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGR 432
+ FR GK VLV T+V ARG+D+E V VINFDLP D Y+HRIGRTGR
Sbjct: 546 EQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTID------EYVHRIGRTGR 599
Query: 433 FGKRGLAVNMVD 444
G G A++ D
Sbjct: 600 CGNTGRAISFFD 611
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 139 bits (349), Expect = 7e-33
Identities = 101/386 (26%), Positives = 188/386 (48%), Gaps = 65/386 (16%)
Query: 92 KSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLA 151
K+F++L + L + +G+ +P+KIQ A+PL L +++I +++G+GKT AF L
Sbjct: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQG--RDIIGLAETGSGKTGAFALP 81
Query: 152 MLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-NKLERGQKIS 210
+L+ + + L L+PT ELA Q + E +G ++ A V G + + + ++
Sbjct: 82 ILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALA 140
Query: 211 EQ--IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNC 268
++ I+I TPG ++D K + + +K V+DEAD I + + +I +++PR+
Sbjct: 141 KKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEAD-RILNMDFETEVDKILKVIPRDR 199
Query: 269 QMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLY 328
+ LFSAT V K + + +P + + +T++ ++QYY+ S KF++
Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPS---KFKS----- 251
Query: 329 GAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLV 388
+R + +F+ +L+
Sbjct: 252 ------------------------------------------KRLGSLNKFKAKARSILL 269
Query: 389 TTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHS 448
T+V +RG+D+ V VV+NFD+P ++ Y+HR+GRT R G+ G A+ V +++
Sbjct: 270 ATDVASRGLDIPHVDVVVNFDIPT------HSKDYIHRVGRTARAGRSGKAITFV-TQYD 322
Query: 449 MNILNRIQEHFNKKIERLDTDDLDEI 474
+ + RI+ KK+ T D DE+
Sbjct: 323 VELFQRIEHLIGKKLPGFPTQD-DEV 347
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 139 bits (349), Expect = 7e-33
Identities = 117/444 (26%), Positives = 212/444 (47%), Gaps = 34/444 (7%)
Query: 14 EAAAESLSNLHLKEEKIKPDTNGAVVKTNANAEKTDEEEKEDRAAQSLLNKL-----IRS 68
E A+ L + KEEK K +N +K D E + A + + ++
Sbjct: 130 ECKAKHLLQVKEKEEKSKL----------SNPQKADSEPESPLNASYVYKEHPFILNLQE 179
Query: 69 NLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLA 128
+ ++N Q + + FE L L + G+ P+ IQ +P+ L
Sbjct: 180 DQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLL 239
Query: 129 EPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKF 188
++++A + +G+GKTAAF+L ++ + +K P L L+PT ELA+Q + +++
Sbjct: 240 G--RDILASADTGSGKTAAFLLPVIMRALFESKTPSALILTPTRELAIQIERQAKELMSG 297
Query: 189 YPELKLAYAVRG----NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEA 244
P +K V G +L R Q+ +++I TPG +LD K ++ +K+ V+DEA
Sbjct: 298 LPRMKTVLLVGGLPLPPQLYRLQQ-HVKVIIATPGRLLD-IIKQSSVELCGVKIVVVDEA 355
Query: 245 DVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETL 304
D M+ G Q Q + I +P +CQ +L SAT S+ + A +++ +P I +
Sbjct: 356 DTML-KMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPC 414
Query: 305 DTIKQ--YYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSK-EGHQVA 361
++Q +V ++ +K + N + ++F + A L+ + K G +
Sbjct: 415 ANVRQIILWVEDPAKKKKLFEILN-DKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSI 473
Query: 362 LLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNE 421
+ E +R +++ EG +V+V+T V RG+D+ V +V+NFD+P D
Sbjct: 474 SIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMD------ 527
Query: 422 TYLHRIGRTGRFGKRGLAVNMVDS 445
Y+H+IGR GR G+ G A+ +++
Sbjct: 528 EYVHQIGRVGRLGQNGTAITFINN 551
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,179,395
Number of Sequences: 37866
Number of extensions: 736566
Number of successful extensions: 2818
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 2550
Number of HSP's gapped (non-prelim): 130
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.