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Search of human proteins with 59958373
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|59958373 PRAME family member 4 [Homo sapiens]
(478 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|59958373 PRAME family member 4 [Homo sapiens] 981 0.0
gi|148356236 PRAME family member 15 [Homo sapiens] 962 0.0
gi|61102721 PRAME family member 9 [Homo sapiens] 962 0.0
gi|61696142 PRAME family member 5 [Homo sapiens] 936 0.0
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 933 0.0
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 931 0.0
gi|58219004 PRAME family member 6 [Homo sapiens] 931 0.0
gi|226437621 PRAME family member 11 [Homo sapiens] 862 0.0
gi|153792112 PRAME family member 20 [Homo sapiens] 782 0.0
gi|153945800 PRAME family member 21 [Homo sapiens] 782 0.0
gi|88942379 PREDICTED: PRAME family member [Homo sapiens] 765 0.0
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 667 0.0
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 564 e-161
gi|59676593 PRAME family member 7 [Homo sapiens] 563 e-160
gi|59676587 PRAME family member 8 [Homo sapiens] 563 e-160
gi|124249372 PRAME family member 12 [Homo sapiens] 561 e-160
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 444 e-124
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 444 e-124
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 444 e-124
gi|46249367 preferentially expressed antigen in melanoma [Homo s... 444 e-124
gi|5174641 preferentially expressed antigen in melanoma [Homo sa... 444 e-124
gi|154800493 PRAME family member 22 [Homo sapiens] 419 e-117
gi|194306638 PRAME family member 3 [Homo sapiens] 413 e-115
gi|153791443 PRAME family member 18 [Homo sapiens] 411 e-115
gi|194306635 PRAME family member 19 [Homo sapiens] 407 e-114
gi|113865933 PRAME family member 16 [Homo sapiens] 406 e-113
gi|157426839 PRAME family member 17 [Homo sapiens] 404 e-113
gi|66954681 PRAME family member 13 [Homo sapiens] 401 e-112
gi|12738831 PRAME family member 1 [Homo sapiens] 400 e-111
gi|194018546 PRAME family member 10 [Homo sapiens] 400 e-111
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 981 bits (2537), Expect = 0.0
Identities = 478/478 (100%), Positives = 478/478 (100%)
Query: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS
Sbjct: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
Query: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL
Sbjct: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI 240
HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI 240
Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 962 bits (2486), Expect = 0.0
Identities = 470/478 (98%), Positives = 473/478 (98%)
Query: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
MKMSI TPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ+
Sbjct: 1 MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
Query: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
WPFRRLPLRPLIKMPCLEAFQAVLDGLDALL GVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
AMAHGCFLNAKRNKKPV+DCPRMRGRQPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLL
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI 240
HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKL+
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLK
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 962 bits (2486), Expect = 0.0
Identities = 470/478 (98%), Positives = 473/478 (98%)
Query: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
MKMSI TPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ+
Sbjct: 1 MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
Query: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
WPFRRLPLRPLIKMPCLEAFQAVLDGLDALL GVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
AMAHGCFLNAKRNKKPV+DCPRMRGRQPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLL
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI 240
HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKL+
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLK
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 936 bits (2420), Expect = 0.0
Identities = 460/476 (96%), Positives = 464/476 (97%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI TPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ+WP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
FRRLPLRPLIKMPCLEAFQAVLDGLDALL GV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
AHGCFLNAKRNKKPV+DCPRMRG+QPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKL+LS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLK LT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
ADGTLCWSRFAQIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 933 bits (2412), Expect = 0.0
Identities = 455/478 (95%), Positives = 466/478 (97%)
Query: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
MKMSI PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQ+
Sbjct: 36 MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95
Query: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
WPFRRLPLRPLIKMPCLEAFQAVLDGLDALL GVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 96 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155
Query: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
AMAHGCFLNAKRNK PV+DCPRMR RQPLTVFVELWLKNRTLDEYLTCLLLWVKQR+DLL
Sbjct: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215
Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI 240
HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKL+
Sbjct: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLV 275
Query: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLK
Sbjct: 276 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLC+ELYPAP+E
Sbjct: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
SYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD G+RSFYDLEADQYCC
Sbjct: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 931 bits (2407), Expect = 0.0
Identities = 458/476 (96%), Positives = 462/476 (97%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI TPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ+WP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
FRRLPLRPLIKMPCLEAFQAVLDGLDALL GV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
AHGCFLNAKRNKKPV+DCPRMRG+QPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKL+LS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLK LT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GIIDSQVNAILPALS CFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
ADGTLCWSRF QIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 931 bits (2406), Expect = 0.0
Identities = 458/476 (96%), Positives = 462/476 (97%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI TPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ+WP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
FRRLPLRPLIKMPCLEAFQAVLDGLDALL GV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A GCFLNAKRNK PV+DCPRMRG+QPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKL+LS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLK LT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
ADGTLCWSRFAQIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 862 bits (2228), Expect = 0.0
Identities = 417/436 (95%), Positives = 427/436 (97%)
Query: 43 MEAFSRRRCEALKLMVQSWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKL 102
MEAFSRRRCEALKLMVQ+WPFRRLPLRPLIKMPCLEAFQAVLDGLDALL GVRPRRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 103 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTL 162
QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNK PV+DCPRMR RQPLTVFVELWLKNRTL
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 163 DEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 222
DEYLTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
Query: 223 LTQFTPYLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 282
LTQFTPYLGH+RNLQKL+LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
Query: 283 LEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 342
LEGHLDQLLSCLKTSLK LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
Query: 343 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 402
LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
Query: 403 HTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPD 462
HTIILKNLC+ELYPAP+ESYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
Query: 463 CGNRSFYDLEADQYCC 478
G+RSFYDLEADQYCC
Sbjct: 421 HGDRSFYDLEADQYCC 436
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 782 bits (2020), Expect = 0.0
Identities = 387/476 (81%), Positives = 416/476 (87%), Gaps = 1/476 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI TPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQ+WP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F RLPL L+K PC E FQAVLDGLDALL VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A C NA N+KPV+DCPRMRG+QPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KL+LS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL L
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
G +C SRFAQ+ AELM RVR LR P+RILFCTDYCP CGNRS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 782 bits (2020), Expect = 0.0
Identities = 387/476 (81%), Positives = 416/476 (87%), Gaps = 1/476 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI TPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQ+WP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F RLPL L+K PC E FQAVLDGLDALL VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A C NA N+KPV+DCPRMRG+QPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KL+LS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL L
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
G +C SRFAQ+ AELM RVR LR P+RILFCTDYCP CGNRS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
Length = 395
Score = 765 bits (1975), Expect = 0.0
Identities = 370/381 (97%), Positives = 374/381 (98%)
Query: 98 RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWL 157
RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNKKPV+DCPRMRGRQPLTVFVELWL
Sbjct: 15 RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
Query: 158 KNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 217
KNRTLDE+LTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 75 KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
Query: 218 WVLPILTQFTPYLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 277
WVLPILTQFTPYLGHMRNLQKL+LSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
Query: 278 NSVSFLEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 337
NSVSFLEGHLDQLLSCLKTSLK LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
Query: 338 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 397
YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
Query: 398 ENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCT 457
ENLLSHTIILKNLC+ELYPAPRESYGADGTLCWSRF QIRAELM RVRDLRHPKRILF T
Sbjct: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
Query: 458 DYCPDCGNRSFYDLEADQYCC 478
DYCPDCGNRSFYDLEADQYCC
Sbjct: 375 DYCPDCGNRSFYDLEADQYCC 395
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 667 bits (1721), Expect = 0.0
Identities = 343/477 (71%), Positives = 383/477 (80%), Gaps = 4/477 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MS+ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQ+WP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F LPL L+K P LE V+DG+D LL VRPRR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
C A ++ VEDCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL MRNL+KL +
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
Query: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
S D RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQLLSCLKTSLK L
Sbjct: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
CGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
YGADGTLCWSRF QIRAELM RVRDLRHPKRILF TDYCPDCGNRSFYDLEADQYCC
Sbjct: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 564 bits (1454), Expect = e-161
Identities = 290/476 (60%), Positives = 353/476 (74%), Gaps = 2/476 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQ+WP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F RLPL L+K P LE+ ++VL+G+D LL VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A F A K+ ++CP +QP VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KL+L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+ +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
G LCW RFA++ AELM +RDLR PK I+FCT CP CG R+ YDLE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 563 bits (1451), Expect = e-160
Identities = 290/476 (60%), Positives = 352/476 (73%), Gaps = 2/476 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQ+WP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F RLPL L+K P LE+ ++VL+G+D LL VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A F A K+ ++CP +QP VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KL+L
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+ +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
G LCW RFA++ AELM RDLR PK I+FCT CP CG R+ YDLE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 563 bits (1450), Expect = e-160
Identities = 289/476 (60%), Positives = 353/476 (74%), Gaps = 2/476 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQ+WP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F RLPL L+K P LE+ ++VL+G+D LL VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A F A K+ ++CP +QP VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CC++L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG MRNL+KL+L
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+ +
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
G LCW RFA++ AELM +RDLR PK I+FCT CP CG R+ YDLE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 561 bits (1447), Expect = e-160
Identities = 292/470 (62%), Positives = 350/470 (74%), Gaps = 2/470 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MS+ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQ+WP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F LPL L+K LE F+AVL+GLDALL VRPRRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A +KR + +CPR G+QPL V ++L KN LDE LT L W KQRK LLH+
Sbjct: 121 ALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG MRNL+KL+L
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
++ VS + ++K++ V QFT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
Query: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
Query: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
GI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL HT+ L L +ELYPAP ESY
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
A G LCW RF+Q+ AELM +RDLR PK I+F T CP CG R+ YDLE
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 444 bits (1141), Expect = e-124
Identities = 243/485 (50%), Positives = 321/485 (66%), Gaps = 13/485 (2%)
Query: 1 MKMSIWTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
+ MS+WT PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK MVQ
Sbjct: 15 ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
Query: 60 SWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLNLGVRPRRWKLQVLDLQ-DVCENFWM 116
+WPF LPL L+K L E F+AVLDGLD LL VRPRRWKLQVLDL+ + ++FW
Sbjct: 75 AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
Query: 117 VWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTC 168
VWS A +P+ ++ G P+ V V+L+LK DE +
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
L+ VK++K++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
Query: 229 YLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
YLG M NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
Query: 289 QLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
QLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
NL LYP P ESY GTL R A + A L + +L P + + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
Query: 468 FYDLE 472
FYD E
Sbjct: 495 FYDPE 499
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 444 bits (1141), Expect = e-124
Identities = 243/485 (50%), Positives = 321/485 (66%), Gaps = 13/485 (2%)
Query: 1 MKMSIWTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
+ MS+WT PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK MVQ
Sbjct: 15 ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
Query: 60 SWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLNLGVRPRRWKLQVLDLQ-DVCENFWM 116
+WPF LPL L+K L E F+AVLDGLD LL VRPRRWKLQVLDL+ + ++FW
Sbjct: 75 AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
Query: 117 VWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTC 168
VWS A +P+ ++ G P+ V V+L+LK DE +
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
L+ VK++K++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
Query: 229 YLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
YLG M NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
Query: 289 QLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
QLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
NL LYP P ESY GTL R A + A L + +L P + + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
Query: 468 FYDLE 472
FYD E
Sbjct: 495 FYDPE 499
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 444 bits (1141), Expect = e-124
Identities = 243/485 (50%), Positives = 321/485 (66%), Gaps = 13/485 (2%)
Query: 1 MKMSIWTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
+ MS+WT PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK MVQ
Sbjct: 15 ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
Query: 60 SWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLNLGVRPRRWKLQVLDLQ-DVCENFWM 116
+WPF LPL L+K L E F+AVLDGLD LL VRPRRWKLQVLDL+ + ++FW
Sbjct: 75 AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
Query: 117 VWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTC 168
VWS A +P+ ++ G P+ V V+L+LK DE +
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
L+ VK++K++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
Query: 229 YLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
YLG M NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
Query: 289 QLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
QLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
NL LYP P ESY GTL R A + A L + +L P + + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
Query: 468 FYDLE 472
FYD E
Sbjct: 495 FYDPE 499
>gi|46249367 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 444 bits (1141), Expect = e-124
Identities = 243/485 (50%), Positives = 321/485 (66%), Gaps = 13/485 (2%)
Query: 1 MKMSIWTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
+ MS+WT PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK MVQ
Sbjct: 15 ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
Query: 60 SWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLNLGVRPRRWKLQVLDLQ-DVCENFWM 116
+WPF LPL L+K L E F+AVLDGLD LL VRPRRWKLQVLDL+ + ++FW
Sbjct: 75 AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
Query: 117 VWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTC 168
VWS A +P+ ++ G P+ V V+L+LK DE +
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
L+ VK++K++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
Query: 229 YLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
YLG M NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
Query: 289 QLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
QLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
NL LYP P ESY GTL R A + A L + +L P + + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
Query: 468 FYDLE 472
FYD E
Sbjct: 495 FYDPE 499
>gi|5174641 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 444 bits (1141), Expect = e-124
Identities = 243/485 (50%), Positives = 321/485 (66%), Gaps = 13/485 (2%)
Query: 1 MKMSIWTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59
+ MS+WT PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK MVQ
Sbjct: 15 ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
Query: 60 SWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLNLGVRPRRWKLQVLDLQ-DVCENFWM 116
+WPF LPL L+K L E F+AVLDGLD LL VRPRRWKLQVLDL+ + ++FW
Sbjct: 75 AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
Query: 117 VWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTC 168
VWS A +P+ ++ G P+ V V+L+LK DE +
Sbjct: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
Query: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228
L+ VK++K++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
Query: 229 YLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288
YLG M NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
Query: 289 QLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348
QLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ LLE
Sbjct: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
Query: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408
+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L
Sbjct: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
Query: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467
NL LYP P ESY GTL R A + A L + +L P + + CP CG+R+
Sbjct: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
Query: 468 FYDLE 472
FYD E
Sbjct: 495 FYDPE 499
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 419 bits (1077), Expect = e-117
Identities = 237/474 (50%), Positives = 308/474 (64%), Gaps = 5/474 (1%)
Query: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
M+MS+ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQ+
Sbjct: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
Query: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
WPF LPL L+K P LE V+DG+D LL VRPRRWKLQVL+L+DV ENFW +WS
Sbjct: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
Query: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
A C A ++ VEDCPR +QPL VF+++ LK + +DE L+ WV+ R+ +
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL MRNL+KL
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
Query: 240 ILSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
Query: 299 KFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
Query: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL +E YPAP
Sbjct: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
Query: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
RES G + ++AELM +R++R PKRI F CP CG LE
Sbjct: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 413 bits (1061), Expect = e-115
Identities = 236/474 (49%), Positives = 306/474 (64%), Gaps = 5/474 (1%)
Query: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
M+MS+ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQ+
Sbjct: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
Query: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
WPF LPL L+K P LE V+DG+D LL VRPRR KLQVL+L+DV ENFW +WS
Sbjct: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSG 120
Query: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
A C A ++ VEDCPR +QPL VF+++ LK + +DE L+ WV+ R+ +
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
Query: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKL 239
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F YL MRNL+KL
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFIRYLSQMRNLRKL 239
Query: 240 ILSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 298
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
Query: 299 KFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 358
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
Query: 359 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAP 418
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL +E YPAP
Sbjct: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
Query: 419 RESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
RES G + ++AELM +R++R PKRI F CP CG LE
Sbjct: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 411 bits (1056), Expect = e-115
Identities = 236/472 (50%), Positives = 304/472 (64%), Gaps = 5/472 (1%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MS P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQ+WP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F LPL L+K P LE V+DG+D LL VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
C A ++ VEDCPR +QPL VF+++ LK +++DE L+ WV+ R+ +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
Query: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
DCGI DS++ ILPALSRC L TF F GN M L++LL HT L NL +E YPAPRE
Sbjct: 358 DCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
S G + ++AELM +R++R P RI F CP CG LE
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 407 bits (1047), Expect = e-114
Identities = 235/472 (49%), Positives = 303/472 (64%), Gaps = 5/472 (1%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MS P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQ+WP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F LPL L+K P LE V+DG+D LL VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
C A ++ VEDCPR +QPL VF+++ LK +++DE L+ WV+ R+ +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
Query: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
DCGI S++ ILPALSRC L TF F GN M L++LL HT L NL +E YPAPRE
Sbjct: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
S G + ++AELM +R++R P RI F CP CG LE
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 406 bits (1044), Expect = e-113
Identities = 234/464 (50%), Positives = 290/464 (62%), Gaps = 3/464 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MS+ +P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQ+WP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F RLPL L+K P LE QAVL GLD LL +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A C A R ++ VED PR QPL VF++L K TLDE L+ L W+ R+ L+HL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L +ELYPAP E
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
G + W A IRAELM +R++R PKRI F CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 404 bits (1038), Expect = e-113
Identities = 233/464 (50%), Positives = 289/464 (62%), Gaps = 3/464 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MS+ +P RLLELAG+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQ+WP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F RLPL L+K P LE QAVL GLD LL +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A C A ++ VED PR QPL VF++L K TLDE L+ L W+ R+ L+HL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CC K++ MP + R++LK V D IQE+E+ K L +F PYL M NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L +ELYPAP E
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
G + W A IRAELM +R++R PKRI F CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 401 bits (1030), Expect = e-112
Identities = 229/477 (48%), Positives = 300/477 (62%), Gaps = 4/477 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQ+WP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F LPL L+K LE +A+L+GL LL RPRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A CF ++ EDCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL M+NL+KL+
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
Query: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
C I SQ++AILP LS C +L TF F N + M L++LL HT L L +E YPAP ES
Sbjct: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
+ + W FA +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 400 bits (1027), Expect = e-111
Identities = 230/478 (48%), Positives = 301/478 (62%), Gaps = 6/478 (1%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MSI PPRLLELAG+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQ+WP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F LPL L+K LE +A+L+GL LL RPRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
A CF ++ EDCPRM QPL VF+++ LK DE L L WV QR+ L+HL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL M+NL+KL+
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
Query: 242 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
Query: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
Query: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
C I SQ++AILPALSRC +L TF F N + + L++LL HT L L +E YPAP E
Sbjct: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
Query: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
S + + W F +RAELM +R++R PKRI CP CG+ +LE CC
Sbjct: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 400 bits (1027), Expect = e-111
Identities = 229/464 (49%), Positives = 292/464 (62%), Gaps = 3/464 (0%)
Query: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
MS+ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQ+WP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
F LPL L+K LE QAVL GLD L+ VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
C A ++ VEDCPRM QPL VF++L LK TLDE L+ L W+ R+ L+HL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
CC K++ MP + R++L+ + D IQE+EV K L +F PYL M NL++L L+
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 243 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
+ YVS + + + FL L Q LY+ +S ++ HL+ LL LK L
Sbjct: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
Query: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
Query: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
C I D Q+ +LPALS C +L TF+F GN M L++LL HT L L +ELYPAP ES
Sbjct: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
Query: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGN 465
G + W IRAELM +R++R PKRI F CP+CG+
Sbjct: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.140 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,215,877
Number of Sequences: 37866
Number of extensions: 784969
Number of successful extensions: 2171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2041
Number of HSP's gapped (non-prelim): 73
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.