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Search of human proteins with 58761530
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58761530 polycomb group ring finger 6 isoform a [Homo
sapiens]
(350 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens] 709 0.0
gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens] 384 e-107
gi|109240538 polycomb group ring finger 1 [Homo sapiens] 155 5e-38
gi|31742478 ring finger protein 3 [Homo sapiens] 152 6e-37
gi|33300663 polycomb group ring finger 5 [Homo sapiens] 146 3e-35
gi|6005964 ring finger protein 110 [Homo sapiens] 145 4e-35
gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens] 144 9e-35
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 66 5e-11
gi|38788260 bromodomain PHD finger transcription factor isoform ... 55 1e-07
gi|38788274 bromodomain PHD finger transcription factor isoform ... 55 1e-07
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 51 2e-06
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 50 3e-06
gi|215422388 death-domain associated protein isoform a [Homo sap... 50 3e-06
gi|215422366 death-domain associated protein isoform b [Homo sap... 50 3e-06
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 50 3e-06
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 50 4e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 50 4e-06
gi|239048905 checkpoint with forkhead and ring finger domains is... 49 5e-06
gi|239048862 checkpoint with forkhead and ring finger domains is... 49 5e-06
gi|239048792 checkpoint with forkhead and ring finger domains is... 49 5e-06
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 49 5e-06
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 49 7e-06
gi|116235474 LKB1 interacting protein [Homo sapiens] 48 1e-05
gi|239048909 checkpoint with forkhead and ring finger domains is... 47 2e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 47 2e-05
gi|239048907 checkpoint with forkhead and ring finger domains is... 47 2e-05
gi|55956788 nucleolin [Homo sapiens] 47 3e-05
gi|17975763 myelin transcription factor 1 [Homo sapiens] 47 3e-05
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 46 4e-05
gi|45331217 zinc finger protein 526 [Homo sapiens] 46 4e-05
>gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]
Length = 350
Score = 709 bits (1831), Expect = 0.0
Identities = 350/350 (100%), Positives = 350/350 (100%)
Query: 1 MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSR 60
MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSR
Sbjct: 1 MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSR 60
Query: 61 PPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
PPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE
Sbjct: 61 PPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
Query: 121 RLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQ 180
RLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQ
Sbjct: 121 RLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQ 180
Query: 181 PLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKV 240
PLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKV
Sbjct: 181 PLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKV 240
Query: 241 LESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDP 300
LESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDP
Sbjct: 241 LESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDP 300
Query: 301 ACQVDIICGDHLLEQYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT 350
ACQVDIICGDHLLEQYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT
Sbjct: 301 ACQVDIICGDHLLEQYQTLREIRRAIGDAAMQDGLLVLHYGLVVSPLKIT 350
>gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]
Length = 275
Score = 384 bits (985), Expect = e-107
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSR 60
MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSR
Sbjct: 1 MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSR 60
Query: 61 PPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
PPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE
Sbjct: 61 PPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
Query: 121 RLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQ 180
RLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQ
Sbjct: 121 RLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQ 180
Query: 181 PLYNI 185
PLYNI
Sbjct: 181 PLYNI 185
Score = 183 bits (465), Expect = 2e-46
Identities = 90/91 (98%), Positives = 90/91 (98%)
Query: 260 IGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTL 319
I ANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTL
Sbjct: 185 ISANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTL 244
Query: 320 REIRRAIGDAAMQDGLLVLHYGLVVSPLKIT 350
REIRRAIGDAAMQDGLLVLHYGLVVSPLKIT
Sbjct: 245 REIRRAIGDAAMQDGLLVLHYGLVVSPLKIT 275
>gi|109240538 polycomb group ring finger 1 [Homo sapiens]
Length = 259
Score = 155 bits (392), Expect = 5e-38
Identities = 81/211 (38%), Positives = 130/211 (61%), Gaps = 9/211 (4%)
Query: 117 DEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVV 176
+EEE + + +L +I+C +C GY +DATTITECLHTFCKSCIV++ S CP CNI +
Sbjct: 30 NEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKI 89
Query: 177 HQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLE-VPKPAVPQPVPSSKG 235
H+TQPL N++LDR +QDIVYKLV L++ E+K++ +FY+ RGL+ V +P +P S+ G
Sbjct: 90 HETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNLG 149
Query: 236 RSKKVLE----SVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKF 291
+ +R +L++ L G ++ L+ K+VR S A + H+ +
Sbjct: 150 LPFSSFDHSKAHYYRYDEQLNLCLERLSSGKDKNK---SVLQNKYVRCSVRAEVRHLRRV 206
Query: 292 LRRKMGLDPACQVDIICGDHLLEQYQTLREI 322
L ++ L+P V ++ + +L + T+++I
Sbjct: 207 LCHRLMLNPQ-HVQLLFDNEVLPDHMTMKQI 236
>gi|31742478 ring finger protein 3 [Homo sapiens]
Length = 242
Score = 152 bits (383), Expect = 6e-37
Identities = 86/239 (35%), Positives = 135/239 (56%), Gaps = 26/239 (10%)
Query: 121 RLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQ 180
R I L ++ +I C +C GYLIDATT+TECLHTFC+SC+V++ +N CP C IV+HQ+
Sbjct: 4 RKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSH 63
Query: 181 PLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKP------AVPQPVPSSK 234
PL I DR +QDIVYKLV L+E E ++ +FY + G+EVP + Q + S +
Sbjct: 64 PLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSHR 123
Query: 235 GRSKKVLES----VFRIPPELD---------MSLLLEFIGANEGTGHFKPLEKKFVRVSG 281
K +S PE D +S+ LE + + L++K++R S
Sbjct: 124 NGETKADDSSNKEAAEEKPEEDNDYHRSDEQVSICLEC-----NSSKLRGLKRKWIRCSA 178
Query: 282 EATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTLREIRRAIGDAAMQDGLLVLHY 340
+AT+ H++KF+ +K+ L ++DI+C + +L + TL+ + + + L+LHY
Sbjct: 179 QATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFV--VVTRWRFKKAPLLLHY 235
>gi|33300663 polycomb group ring finger 5 [Homo sapiens]
Length = 256
Score = 146 bits (368), Expect = 3e-35
Identities = 85/240 (35%), Positives = 127/240 (52%), Gaps = 21/240 (8%)
Query: 125 LSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYN 184
+ + PYI C ICKGYLI TT+TECLHTFCK+CIV+HF SN CP+C VH+T PL
Sbjct: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
Query: 185 IRLDRQLQDIVYKLVINLEEREKKQMHDFYK-----ERGLEVPKPAVPQPVPSSKGRSKK 239
+RLD L++I++KLV L E+E ++ +F+K E G + A +P +G +
Sbjct: 69 LRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKA-DKPKVDEEGDENE 127
Query: 240 VLESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLD 299
+ R P++ + L G K L KKF+R S T+G ++KFL K+ L
Sbjct: 128 DDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLP 187
Query: 300 PACQVDIICG------DHLLE---------QYQTLREIRRAIGDAAMQDGLLVLHYGLVV 344
+ ++D++C DH +E + + R + + QDG L Y +V+
Sbjct: 188 SSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVL 247
>gi|6005964 ring finger protein 110 [Homo sapiens]
Length = 344
Score = 145 bits (367), Expect = 4e-35
Identities = 81/211 (38%), Positives = 122/211 (57%), Gaps = 17/211 (8%)
Query: 123 INLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPL 182
I ++EL P+++C++C GY IDATTI ECLH+FCK+CIVR+ + CP C++ VH+T+PL
Sbjct: 7 IKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPL 66
Query: 183 YNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKVLE 242
+IR D+ LQDIVYKLV L + E K+ DFY P P S++ R + + +
Sbjct: 67 LSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFY------AAYPLTEVPNGSNEDRGEVLEQ 120
Query: 243 SVFRIPPELDMSLLLEFI-GANEGTGHFKPLEK----------KFVRVSGEATIGHVEKF 291
+ + +SL +EF GA + PLE +F+R T+ H+ KF
Sbjct: 121 EKGALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKF 180
Query: 292 LRRKMGLDPACQVDIICGDHLLEQYQTLREI 322
LR KM + +V+++ D L++Y TL +I
Sbjct: 181 LRNKMDVPSKYKVEVLYEDEPLKEYYTLMDI 211
>gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
Length = 326
Score = 144 bits (364), Expect = 9e-35
Identities = 80/209 (38%), Positives = 118/209 (56%), Gaps = 15/209 (7%)
Query: 123 INLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPL 182
I ++EL P+++C +C GY IDATTI ECLH+FCK+CIVR+ S CP C++ VH+T+PL
Sbjct: 7 IKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPL 66
Query: 183 YNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKVLE 242
NIR D+ LQDIVYKLV L + E K+ DFY P+ S++ R + E
Sbjct: 67 LNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFY------AAHPSADAANGSNEDRGEVADE 120
Query: 243 SVFRIPPELDMSLLLEFIGAN---------EGTGHFKPLEKKFVRVSGEATIGHVEKFLR 293
I + +SL +EF N + + +K+++R T+ H+ KFLR
Sbjct: 121 DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLR 180
Query: 294 RKMGLDPACQVDIICGDHLLEQYQTLREI 322
KM + Q+D++ + L+ Y TL +I
Sbjct: 181 SKMDIPNTFQIDVMYEEEPLKDYYTLMDI 209
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 65.9 bits (159), Expect = 5e-11
Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 23 LPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDE 82
LPPPPP PP P P L G PG G PP LE + ++ E+E+E
Sbjct: 839 LPPPPPPPPPVPGPVTLP----PPQLVPEGTPG--GGGPPALEEDLTVININSSDEEEEE 892
Query: 83 ELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E EEEEE EEEEEEEE+ E ++ E+EEE
Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEE 930
Score = 65.1 bits (157), Expect = 9e-11
Identities = 43/103 (41%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Query: 18 EGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRF 77
E A P P P PP P P P L G PG G PP LE + ++
Sbjct: 830 EELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPG--GGGPPALEEDLTVININSSD 887
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E+E+EE EEEEE EEEEEEEEED E ++ E+EEE
Sbjct: 888 EEEEEE-EEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/127 (31%), Positives = 45/127 (35%), Gaps = 39/127 (30%)
Query: 24 PPPPPVS------PPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGR----- 72
PPPPPV PP L P G GP L E S E E E
Sbjct: 844 PPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEE 903
Query: 73 ---------------------------FRGRFEDEDEELEEEEELEEEEEEEE-EDMSHF 104
F FE+E+ ELEEEEE E+EEEEEE E++
Sbjct: 904 EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963
Query: 105 SLRLEGG 111
GG
Sbjct: 964 EFGTAGG 970
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 26/122 (21%)
Query: 1 MEGVAVVTAGSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETG------AP 54
+E V + G+ G EGA PPPP PPAL P + + P P E G P
Sbjct: 957 LEEVEDLEFGTAGGEVEEGA----PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEP 1012
Query: 55 GCSGSR----PPELEPERSLGRFRGRFEDED-------EELEEEE-----ELEEEEEEEE 98
G R P L PE + E E +EL EEE L EEE E+
Sbjct: 1013 GTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDG 1072
Query: 99 ED 100
D
Sbjct: 1073 SD 1074
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/97 (37%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEE 83
PPPPP +PP+ T AP G G TG G G R++ + + +EE
Sbjct: 77 PPPPPPAPPS-TSAPGRGGRGGGG-GRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEE 134
Query: 84 LEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
EEE+ + EEEEEE+ D QDSED+EE
Sbjct: 135 EEEEDMVSEEEEEEDGDAEE--------TQDSEDDEE 163
Score = 30.4 bits (67), Expect = 2.5
Identities = 20/56 (35%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
Query: 14 AAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERS 69
AA PP PP PP+ P PA G LS P S R E E + S
Sbjct: 2650 AAPCPPVTPAPPAPPAPPPSPPPPPAVQHTG--LLSTPTLPAASQKRKREEEKDSS 2703
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 54.7 bits (130), Expect = 1e-07
Identities = 36/97 (37%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEE 83
PPPPP +PP+ T AP G G TG G G R++ + + +EE
Sbjct: 77 PPPPPPAPPS-TSAPGRGGRGGGG-GRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEE 134
Query: 84 LEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
EEE+ + EEEEEE+ D QDSED+EE
Sbjct: 135 EEEEDMVSEEEEEEDGDAEE--------TQDSEDDEE 163
Score = 30.4 bits (67), Expect = 2.5
Identities = 20/56 (35%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
Query: 14 AAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERS 69
AA PP PP PP+ P PA G LS P S R E E + S
Sbjct: 2667 AAPCPPVTPAPPAPPAPPPSPPPPPAVQHTG--LLSTPTLPAASQKRKREEEKDSS 2720
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 50.8 bits (120), Expect = 2e-06
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 24/142 (16%)
Query: 65 EPERSLGRFRGRFEDEDEELEE-EEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLI 123
E RS F + +++ELE+ +EE E+ + ++EE +SH + LE Q
Sbjct: 353 ELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQ---------- 402
Query: 124 NLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLY 183
C IC Y I+A T+ C H+FC CI CP C + Y
Sbjct: 403 ----------CIICSEYFIEAVTLN-CAHSFCSYCINEWMKRKIECPICRKDI--KSKTY 449
Query: 184 NIRLDRQLQDIVYKLVINLEER 205
++ LD + +V L ++ER
Sbjct: 450 SLVLDNCINKMVNNLSSEVKER 471
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 50.1 bits (118), Expect = 3e-06
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 12/78 (15%)
Query: 43 EGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMS 102
EGP+ ++ G P S + + + E S ++E+EE EEEEE E + EEEED+
Sbjct: 417 EGPSGMASQGCPSASRAETDDEDDEES--------DEEEEEEEEEEEEEATDSEEEEDLE 468
Query: 103 HFSLRLEGGRQDSEDEEE 120
+++ G++D E+E+E
Sbjct: 469 ----QMQEGQEDDEEEDE 482
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 50.1 bits (118), Expect = 3e-06
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 12/78 (15%)
Query: 43 EGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMS 102
EGP+ ++ G P S + + + E S ++E+EE EEEEE E + EEEED+
Sbjct: 417 EGPSGMASQGCPSASRAETDDEDDEES--------DEEEEEEEEEEEEEATDSEEEEDLE 468
Query: 103 HFSLRLEGGRQDSEDEEE 120
+++ G++D E+E+E
Sbjct: 469 ----QMQEGQEDDEEEDE 482
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 50.1 bits (118), Expect = 3e-06
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 12/78 (15%)
Query: 43 EGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMS 102
EGP+ ++ G P S + + + E S ++E+EE EEEEE E + EEEED+
Sbjct: 429 EGPSGMASQGCPSASRAETDDEDDEES--------DEEEEEEEEEEEEEATDSEEEEDLE 480
Query: 103 HFSLRLEGGRQDSEDEEE 120
+++ G++D E+E+E
Sbjct: 481 ----QMQEGQEDDEEEDE 494
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 50.1 bits (118), Expect = 3e-06
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 133 LCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQ 192
+C IC +I+ +T+C H+FC CI + +NRCPKCN VV LY L +
Sbjct: 135 VCPICFD-MIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFL---VN 190
Query: 193 DIVYKLVINLEEREKKQMHDFYKERG 218
+++ K EE+ K H G
Sbjct: 191 ELILKQKQRFEEKRFKLDHSVSSTNG 216
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 49.7 bits (117), Expect = 4e-06
Identities = 28/65 (43%), Positives = 39/65 (60%)
Query: 60 RPPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEE 119
R E E + R ++E++E EEEEE EEEEEEEEE+ S L +++E EE
Sbjct: 77 RREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEE 136
Query: 120 ERLIN 124
+RLI+
Sbjct: 137 KRLIS 141
Score = 37.7 bits (86), Expect = 0.015
Identities = 25/65 (38%), Positives = 32/65 (49%), Gaps = 17/65 (26%)
Query: 65 EPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLIN 124
E R R G+ +++EE EEEEE EEEEEEEEE+ EEE ++
Sbjct: 80 EKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEE-----------------EEEEEVS 122
Query: 125 LSELT 129
S T
Sbjct: 123 FSLAT 127
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 49.7 bits (117), Expect = 4e-06
Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 11/92 (11%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPA-PLSETGAPGCSGSR------PPELEPERSLGRFRGR 76
PPPPP +PPA PAP P P E +P + + P P S G
Sbjct: 210 PPPPPPAPPA-PPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGT---P 265
Query: 77 FEDEDEELEEEEELEEEEEEEEEDMSHFSLRL 108
+E+EE EEEEE EEE+EEEEE +S R+
Sbjct: 266 SPEEEEEEEEEEEEEEEDEEEEEGLSQSISRI 297
Score = 48.1 bits (113), Expect = 1e-05
Identities = 40/98 (40%), Positives = 50/98 (51%), Gaps = 17/98 (17%)
Query: 9 AGSVGAAKT-----EGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPE 63
AG+ GA +T E AA +P PP P A P PA P S+T C + PE
Sbjct: 954 AGTKGAEETSWSGEERAAKVPSTPP--PKAAPPPPAL-----TPDSQTVDSSC---KTPE 1003
Query: 64 LE--PERSLGRFRGRFEDEDEELEEEEELEEEEEEEEE 99
+ PE + R E+EE EEEEE EEEEEEE++
Sbjct: 1004 VSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQ 1041
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 25/108 (23%)
Query: 18 EGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGC---------------SGSRPP 62
+G A PP P + + +P+P++ P P AP + P
Sbjct: 181 DGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSP 240
Query: 63 ELEPERSLGRFR----------GRFEDEDEELEEEEELEEEEEEEEED 100
PE+ F G E+EE EEEEE EEEE+EEEE+
Sbjct: 241 PPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEE 288
>gi|239048905 checkpoint with forkhead and ring finger domains
isoform 3 [Homo sapiens]
Length = 652
Score = 49.3 bits (116), Expect = 5e-06
Identities = 53/254 (20%), Positives = 87/254 (34%), Gaps = 54/254 (21%)
Query: 25 PPPPVSPPALTPAPAAGEEGPAPLSETGAPGC---------SGSRPPELE---------- 65
P P S L P +A P+P + C GS P
Sbjct: 163 PQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVASDEVSSFASAL 222
Query: 66 PERSLGRFRGRFEDEDEELEEEE-------------ELEEEEEEEEEDMSHFSLRLEGGR 112
P+R F + E+LE + +L + H +R G+
Sbjct: 223 PDRKTASFSSLEPQDQEDLEPVKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGK 282
Query: 113 QDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKC 172
D +E + C IC+ L D ++ C+HTFC +C S+ CP C
Sbjct: 283 PDKMEET------------LTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTC 330
Query: 173 NIVVHQTQPLYNIRLDRQLQDIVYKLVINLEER----EKKQMHDFYKERGLEVPKPAVPQ 228
P+ I + L ++V +I ++ E Q D + ++ +P V +
Sbjct: 331 RC------PVERICKNHILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR 384
Query: 229 PVPSSKGRSKKVLE 242
+G S+ +LE
Sbjct: 385 SFSDEEGSSEDLLE 398
>gi|239048862 checkpoint with forkhead and ring finger domains
isoform 2 [Homo sapiens]
Length = 663
Score = 49.3 bits (116), Expect = 5e-06
Identities = 53/254 (20%), Positives = 87/254 (34%), Gaps = 54/254 (21%)
Query: 25 PPPPVSPPALTPAPAAGEEGPAPLSETGAPGC---------SGSRPPELE---------- 65
P P S L P +A P+P + C GS P
Sbjct: 175 PQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVASDEVSSFASAL 234
Query: 66 PERSLGRFRGRFEDEDEELEEEE-------------ELEEEEEEEEEDMSHFSLRLEGGR 112
P+R F + E+LE + +L + H +R G+
Sbjct: 235 PDRKTASFSSLEPQDQEDLEPVKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGK 294
Query: 113 QDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKC 172
D +E + C IC+ L D ++ C+HTFC +C S+ CP C
Sbjct: 295 PDKMEET------------LTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTC 342
Query: 173 NIVVHQTQPLYNIRLDRQLQDIVYKLVINLEER----EKKQMHDFYKERGLEVPKPAVPQ 228
P+ I + L ++V +I ++ E Q D + ++ +P V +
Sbjct: 343 RC------PVERICKNHILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR 396
Query: 229 PVPSSKGRSKKVLE 242
+G S+ +LE
Sbjct: 397 SFSDEEGSSEDLLE 410
>gi|239048792 checkpoint with forkhead and ring finger domains
isoform 1 [Homo sapiens]
Length = 664
Score = 49.3 bits (116), Expect = 5e-06
Identities = 53/254 (20%), Positives = 87/254 (34%), Gaps = 54/254 (21%)
Query: 25 PPPPVSPPALTPAPAAGEEGPAPLSETGAPGC---------SGSRPPELE---------- 65
P P S L P +A P+P + C GS P
Sbjct: 175 PQPSTSTSDLFPTASASSTEPSPAGRERSSSCGSGGGGISPKGSGPSVASDEVSSFASAL 234
Query: 66 PERSLGRFRGRFEDEDEELEEEE-------------ELEEEEEEEEEDMSHFSLRLEGGR 112
P+R F + E+LE + +L + H +R G+
Sbjct: 235 PDRKTASFSSLEPQDQEDLEPVKKKMRGDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGK 294
Query: 113 QDSEDEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKC 172
D +E + C IC+ L D ++ C+HTFC +C S+ CP C
Sbjct: 295 PDKMEET------------LTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTC 342
Query: 173 NIVVHQTQPLYNIRLDRQLQDIVYKLVINLEER----EKKQMHDFYKERGLEVPKPAVPQ 228
P+ I + L ++V +I ++ E Q D + ++ +P V +
Sbjct: 343 RC------PVERICKNHILNNLVEAYLIQHPDKSRSEEDVQSMDARNKITQDMLQPKVRR 396
Query: 229 PVPSSKGRSKKVLE 242
+G S+ +LE
Sbjct: 397 SFSDEEGSSEDLLE 410
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 49.3 bits (116), Expect = 5e-06
Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 133 LCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQ 192
+C IC +I+ +T+C H+FC CI + +NRCPKCN VV LY L +
Sbjct: 135 VCPICFD-MIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFL---VN 190
Query: 193 DIVYKLVINLEEREKKQMH 211
+++ K EE+ K H
Sbjct: 191 ELILKQKQRFEEKRFKLDH 209
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 48.9 bits (115), Expect = 7e-06
Identities = 53/207 (25%), Positives = 77/207 (37%), Gaps = 47/207 (22%)
Query: 26 PPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEELE 85
P P P + PA AG+ E + G SG + + E G + EDE
Sbjct: 14 PGPDGHPQVGPADPAGD------FEESSVGSSGDSGDDSDSEHGDGT-----DGEDEGAS 62
Query: 86 EEEELEEEE-EEEEEDMSHFSLRLEG--------GRQDSEDEEERLINLSELTPYILCSI 136
EEE+LE+ E+ ED L + G G +S+D+ E C I
Sbjct: 63 EEEDLEDRSGSEDSEDDGETLLEVAGTQGKLEAAGSFNSDDDAES------------CPI 110
Query: 137 CKGYLIDATTIT--ECLHTFCKSCIVRHFYYSNRCP------KCNIV-------VHQTQP 181
C D T C H FC CIV +N CP KC + + + P
Sbjct: 111 CLNAFRDQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTLFKCICIRAQFGGKILRKIP 170
Query: 182 LYNIRLDRQLQDIVYKLVINLEEREKK 208
+ N + + +D + V +RE +
Sbjct: 171 VENTKASEEEEDPTFCEVCGRSDREDR 197
Score = 30.8 bits (68), Expect = 1.9
Identities = 30/107 (28%), Positives = 39/107 (36%), Gaps = 13/107 (12%)
Query: 24 PPPPPVS---PPALTPAPAAGEEGP-----APLSETGAPGCSG-----SRPPELEPERSL 70
PPP P P L P A E P AP + +P SG +RP E+ + L
Sbjct: 1333 PPPLPEGTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDSPSASGRVQEAARPEEVVSQTPL 1392
Query: 71 GRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSED 117
R R + L+E E E+ H + G D ED
Sbjct: 1393 LRSRALVKRVTWNLQESESSAPAEDRAPRAPLHRPQKPREGAWDMED 1439
>gi|116235474 LKB1 interacting protein [Homo sapiens]
Length = 1099
Score = 48.1 bits (113), Expect = 1e-05
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 13/115 (11%)
Query: 23 LPPPPPVSPPALTPAPAAGEE-GPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDED 81
LP P S P+ PA + G + P P +P +R P+ P++ R ++E+
Sbjct: 455 LPATPTTSAPSAPPASSQGPDTAPRP-----SPPQEEARGPQESPQKMSEEVRAEPQEEE 509
Query: 82 EELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSELTPYILCSI 136
EE E +EE EE E E+ + E G ++ E+++++ + P ++C +
Sbjct: 510 EEKEGKEEKEEGEMVEQGEE-------EAGEEEEEEQDQKEVEAELCRPLLVCPL 557
>gi|239048909 checkpoint with forkhead and ring finger domains
isoform 5 [Homo sapiens]
Length = 572
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/223 (22%), Positives = 87/223 (39%), Gaps = 34/223 (15%)
Query: 29 VSPPALTPAPAAGEEGP--APLSETGAPGCSGSRPPE---LEPERSLGRFRGRFEDEDEE 83
+SP P+ A+ E + L + S P + LEP + + RG D +
Sbjct: 121 ISPKGSGPSVASDEVSSFASALPDRKTASFSSLEPQDQEDLEPVKK--KMRG-----DGD 173
Query: 84 LEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSELTPYILCSICKGYLID 143
L+ +L + H +R G+ D +E + C IC+ L D
Sbjct: 174 LDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEET------------LTCIICQDLLHD 221
Query: 144 ATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLE 203
++ C+HTFC +C S+ CP C P+ I + L ++V +I
Sbjct: 222 CVSLQPCMHTFCAACYSGWMERSSLCPTCRC------PVERICKNHILNNLVEAYLIQHP 275
Query: 204 ER----EKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKVLE 242
++ E Q D + ++ +P V + +G S+ +LE
Sbjct: 276 DKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLE 318
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 17/94 (18%)
Query: 31 PPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPER--SLGRFRGRF--EDEDEELEE 86
P TPA E+ P E G PG G++PP+ + ER + G+ R F + E EE +
Sbjct: 912 PRPSTPAEE-DEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQ 970
Query: 87 EEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E E++EE++EED ++ ED EE
Sbjct: 971 ESSSEKDEEDDEED------------EEDEDREE 992
Score = 42.4 bits (98), Expect = 6e-04
Identities = 33/87 (37%), Positives = 40/87 (45%), Gaps = 9/87 (10%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEE 83
PP P + PP PAPAA PA AP + E +P++ + + EE
Sbjct: 1310 PPAPALRPPEPVPAPAALFSSPAD-EVLEAPEVVVAEAEEPKPQQ--------LQQQREE 1360
Query: 84 LEEEEELEEEEEEEEEDMSHFSLRLEG 110
EEE E E EEEEEE S S EG
Sbjct: 1361 GEEEGEEEGEEEEEESSDSSSSSDGEG 1387
Score = 37.0 bits (84), Expect = 0.026
Identities = 34/98 (34%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 17 TEGAAALPPPPPV-SPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRG 75
T A AL PP PV +P AL +P A E AP E +P +L+ +R G G
Sbjct: 1309 TPPAPALRPPEPVPAPAALFSSP-ADEVLEAP--EVVVAEAEEPKPQQLQQQREEGEEEG 1365
Query: 76 RFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQ 113
E+E EE EEE + E + SLR R+
Sbjct: 1366 --EEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRR 1401
Score = 31.6 bits (70), Expect = 1.1
Identities = 27/92 (29%), Positives = 34/92 (36%), Gaps = 14/92 (15%)
Query: 25 PPPPVSPPALTPAPAAGEEGPAPLSE---------TGAPGCSGSRPPELEPERSLGRFRG 75
PP +PP P P G G P E +P SGS PE E
Sbjct: 427 PPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHS 486
Query: 76 RFEDEDEELEEEEE-----LEEEEEEEEEDMS 102
+ E L +E+ L + EEEEE+ S
Sbjct: 487 SLDSRIEMLLKEQRSKFSFLASDTEEEEENSS 518
Score = 30.0 bits (66), Expect = 3.2
Identities = 12/25 (48%), Positives = 12/25 (48%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPAPL 48
PP PP PPA P P P PL
Sbjct: 1133 PPEPPAGPPAPAPRPDERPSSPIPL 1157
>gi|239048907 checkpoint with forkhead and ring finger domains
isoform 4 [Homo sapiens]
Length = 623
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/223 (22%), Positives = 87/223 (39%), Gaps = 34/223 (15%)
Query: 29 VSPPALTPAPAAGEEGP--APLSETGAPGCSGSRPPE---LEPERSLGRFRGRFEDEDEE 83
+SP P+ A+ E + L + S P + LEP + + RG D +
Sbjct: 172 ISPKGSGPSVASDEVSSFASALPDRKTASFSSLEPQDQEDLEPVKK--KMRG-----DGD 224
Query: 84 LEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEERLINLSELTPYILCSICKGYLID 143
L+ +L + H +R G+ D +E + C IC+ L D
Sbjct: 225 LDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEET------------LTCIICQDLLHD 272
Query: 144 ATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVINLE 203
++ C+HTFC +C S+ CP C P+ I + L ++V +I
Sbjct: 273 CVSLQPCMHTFCAACYSGWMERSSLCPTCRC------PVERICKNHILNNLVEAYLIQHP 326
Query: 204 ER----EKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKVLE 242
++ E Q D + ++ +P V + +G S+ +LE
Sbjct: 327 DKSRSEEDVQSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLE 369
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 47.0 bits (110), Expect = 3e-05
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 4 VAVVTAGSVGAAKTEG--AAALPPPPPVSPPALTPAPAAGEEGPAP-LSETGAPGCSGSR 60
VAV T AA T G AAA P V+P P G++G P + PG G+
Sbjct: 72 VAVATPAKK-AAVTPGKKAAATPAKKTVTPAKAVTTP--GKKGATPGKALVATPGKKGAA 128
Query: 61 PPELEPERSLG-RFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEE 119
P + + E+ED++ EE+EE +E+E+E+E+++ +++ SEDE+
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDED 188
Query: 120 E 120
+
Sbjct: 189 D 189
Score = 35.4 bits (80), Expect = 0.077
Identities = 16/43 (37%), Positives = 29/43 (67%), Gaps = 6/43 (13%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
EDEDEE ++E+E ++++E++E+D E ++ E+EEE
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDEDDDD------EDDEEEEEEEEE 270
Score = 34.7 bits (78), Expect = 0.13
Identities = 14/23 (60%), Positives = 21/23 (91%)
Query: 78 EDEDEELEEEEELEEEEEEEEED 100
+DED+E +++E+ EEEEEEEEE+
Sbjct: 249 DDEDDEDDDDEDDEEEEEEEEEE 271
Score = 32.3 bits (72), Expect = 0.65
Identities = 12/44 (27%), Positives = 30/44 (68%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEER 121
ED+D++ ++E++ +E++EEEEE+ ++ G++ E +++
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQK 288
Score = 32.3 bits (72), Expect = 0.65
Identities = 16/44 (36%), Positives = 27/44 (61%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEER 121
+DED++ E++EE EEEEEEE + + E +Q + E ++
Sbjct: 252 DDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKK 295
Score = 31.6 bits (70), Expect = 1.1
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 13/63 (20%)
Query: 58 GSRPPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSED 117
G + ++ P ++ E+ED+E E++++ E++E++++ED D E+
Sbjct: 218 GKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDED-------------DEEE 264
Query: 118 EEE 120
EEE
Sbjct: 265 EEE 267
Score = 29.6 bits (65), Expect = 4.2
Identities = 11/24 (45%), Positives = 20/24 (83%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDM 101
+DED+E +E+++ +EE++ EEE M
Sbjct: 188 DDEDDEDDEDDDDDEEDDSEEEAM 211
Score = 28.5 bits (62), Expect = 9.4
Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 13/56 (23%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQ-------------DSEDEEE 120
EDED+E +E++E ++++EE++ + G++ + EDEEE
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 46.6 bits (109), Expect = 3e-05
Identities = 40/116 (34%), Positives = 48/116 (41%), Gaps = 14/116 (12%)
Query: 19 GAAALPPPPPVSPPALTPAPAAGEEGPAPL--------------SETGAPGCSGSRPPEL 64
G AA P P V AA EEG L +E C S
Sbjct: 185 GQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAA 244
Query: 65 EPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E S + E+EDEE EEEEE EEE+EEEEE+ E ++ E+EEE
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Score = 46.2 bits (108), Expect = 4e-05
Identities = 25/56 (44%), Positives = 32/56 (57%)
Query: 65 EPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E + G EDE+EE EEEEE E+EEEEEEE+ E ++ E+EEE
Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
Score = 45.1 bits (105), Expect = 1e-04
Identities = 23/43 (53%), Positives = 29/43 (67%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E+E+EE EEEEE EEEEEEEEE+ E ++ E+EEE
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/43 (51%), Positives = 29/43 (67%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E+E+EE EEEE+ EEEEEEEEE+ E ++ E+EEE
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 44.3 bits (103), Expect = 2e-04
Identities = 22/43 (51%), Positives = 29/43 (67%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
E+E+EE EEE+E EEEEEEEEE+ E ++ E+EEE
Sbjct: 264 EEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 43.1 bits (100), Expect = 4e-04
Identities = 21/43 (48%), Positives = 29/43 (67%)
Query: 78 EDEDEELEEEEELEEEEEEEEEDMSHFSLRLEGGRQDSEDEEE 120
++E+EE EEEEE +EEEEEEEE+ E ++ E+EEE
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 46.2 bits (108), Expect = 4e-05
Identities = 38/120 (31%), Positives = 50/120 (41%), Gaps = 24/120 (20%)
Query: 1 MEGVAVVTAGSVGAAKTEGAAALPPPP-------------------PVSPPALTPAPAA- 40
MEG + AGS + A L P P+ P A +P ++
Sbjct: 373 MEGEEALPAGSAAGPEQPQAGLLTPSTLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSE 432
Query: 41 GEEGPAPLSETGAPGCSGSRPPELEPERSLGRFRGRFEDEDEELEEEEELEEEEEEEEED 100
G++ A E G ++EP E+E+EE EEEEE EEEEEEEEED
Sbjct: 433 GKDSGAAEGEKQEVGDGDCFSEKVEPAEE----EAEEEEEEEEAEEEEEEEEEEEEEEED 488
Score = 34.7 bits (78), Expect = 0.13
Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 21/128 (16%)
Query: 10 GSVGAAKTEGAAALPPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPP----ELE 65
G + EG ALP P P AG P+ L G S + P L
Sbjct: 366 GKFSGIRMEGEEALPAGSAAGPEQ----PQAGLLTPSTLLNLGGLTSSVLKTPITSVPLG 421
Query: 66 P------ERSLGRFRGRFEDEDEEL-------EEEEELEEEEEEEEEDMSHFSLRLEGGR 112
P + S G+ G E E +E+ E+ E EEE EEEEE+ E
Sbjct: 422 PLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEE 481
Query: 113 QDSEDEEE 120
++ E+E+E
Sbjct: 482 EEEEEEDE 489
Score = 30.8 bits (68), Expect = 1.9
Identities = 18/43 (41%), Positives = 18/43 (41%), Gaps = 9/43 (20%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRPPELEP 66
PPPPP PP L AP P P S P S PP P
Sbjct: 2041 PPPPPPPPPPLPAAP------PQPAS---TPAIPASAPPITSP 2074
Score = 30.0 bits (66), Expect = 3.2
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 8/52 (15%)
Query: 22 ALPPPPPVSPPALTPAPAAGEEGPAPLS-------ETGAPGCSGSRPPELEP 66
+LP PPP +PP P P + P+ LS T P + PP+L P
Sbjct: 2479 SLPQPPPQAPPPQCPLPQS-SPSPSQLSHLPLKPLHTSTPQQLANLPPQLIP 2529
Score = 29.6 bits (65), Expect = 4.2
Identities = 14/38 (36%), Positives = 19/38 (50%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSGSRP 61
PPPPP PA P PA+ PA +P + ++P
Sbjct: 2044 PPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQP 2081
>gi|45331217 zinc finger protein 526 [Homo sapiens]
Length = 670
Score = 46.2 bits (108), Expect = 4e-05
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Query: 24 PPPPPVSPPALTPAPAAGEEGPAPLSETGAPGCSG-SRPPELEPERSLGRFRGRFEDEDE 82
P PPP+ PP TP P + P CS PE E F ++E
Sbjct: 172 PVPPPLPPP--TPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERN 229
Query: 83 ELEEEEELEEEEEEEEEDMSHFSLRLEGG 111
LEEEEE +EE+EE++E+M E G
Sbjct: 230 GLEEEEEDDEEDEEDDEEMEDEEAMAEVG 258
Score = 30.4 bits (67), Expect = 2.5
Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 6/36 (16%)
Query: 9 AGSVGAAKTEGAAA------LPPPPPVSPPALTPAP 38
AG GA T A PPPPP +PPA P P
Sbjct: 410 AGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCP 445
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.137 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,233,792
Number of Sequences: 37866
Number of extensions: 1105020
Number of successful extensions: 40837
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 911
Number of HSP's successfully gapped in prelim test: 1105
Number of HSP's that attempted gapping in prelim test: 16803
Number of HSP's gapped (non-prelim): 13902
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.