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Search of human proteins with 58535455
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58535455 androgen receptor isoform 2 [Homo sapiens]
(388 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58535455 androgen receptor isoform 2 [Homo sapiens] 801 0.0
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 785 0.0
gi|110611914 progesterone receptor [Homo sapiens] 441 e-124
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho... 394 e-109
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-109
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-109
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-109
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof... 391 e-109
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo... 391 e-109
gi|66528677 nuclear receptor subfamily 3, group C, member 1 isof... 389 e-108
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof... 354 9e-98
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 158 7e-39
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 158 7e-39
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 158 7e-39
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 158 7e-39
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens] 158 9e-39
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens] 158 9e-39
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens] 158 9e-39
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 147 2e-35
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 146 4e-35
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 146 4e-35
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 146 4e-35
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 146 4e-35
gi|238550159 estrogen-related receptor beta [Homo sapiens] 144 2e-34
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 117 2e-26
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 116 3e-26
gi|11415052 retinoid X receptor, beta [Homo sapiens] 116 3e-26
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 116 4e-26
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 111 1e-24
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens] 109 5e-24
>gi|58535455 androgen receptor isoform 2 [Homo sapiens]
Length = 388
Score = 801 bits (2068), Expect = 0.0
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 1 MILWLHSLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQ 60
MILWLHSLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQ
Sbjct: 1 MILWLHSLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQ 60
Query: 61 KYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP 120
KYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP
Sbjct: 61 KYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP 120
Query: 121 TEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQ 180
TEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQ
Sbjct: 121 TEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQ 180
Query: 181 LVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFN 240
LVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFN
Sbjct: 181 LVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFN 240
Query: 241 EYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELR 300
EYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELR
Sbjct: 241 EYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELR 300
Query: 301 MNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDF 360
MNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDF
Sbjct: 301 MNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDF 360
Query: 361 PEMMAEIISVQVPKILSGKVKPIYFHTQ 388
PEMMAEIISVQVPKILSGKVKPIYFHTQ
Sbjct: 361 PEMMAEIISVQVPKILSGKVKPIYFHTQ 388
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 785 bits (2028), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 8 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR 67
LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR
Sbjct: 540 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR 599
Query: 68 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK 127
NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK
Sbjct: 600 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK 659
Query: 128 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW 187
LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW
Sbjct: 660 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW 719
Query: 188 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS 247
AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS
Sbjct: 720 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS 779
Query: 248 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL 307
RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL
Sbjct: 780 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL 839
Query: 308 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI 367
DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI
Sbjct: 840 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI 899
Query: 368 ISVQVPKILSGKVKPIYFHTQ 388
ISVQVPKILSGKVKPIYFHTQ
Sbjct: 900 ISVQVPKILSGKVKPIYFHTQ 920
>gi|110611914 progesterone receptor [Homo sapiens]
Length = 933
Score = 441 bits (1133), Expect = e-124
Identities = 205/369 (55%), Positives = 277/369 (75%), Gaps = 6/369 (1%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
PQK CLICGDEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC +DK RRKNCP+C
Sbjct: 563 PQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPAC 622
Query: 84 RLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP------TEETTQKLTVSHIEGYE 137
RLRKC +AGM LG RK KK +++ +A + P ++ +Q+ T S + +
Sbjct: 623 RLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQ 682
Query: 138 CQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNL 197
P +N+L +IEP V+ AGHDN +PD+ ++LL+SLN+LGERQL+ VVKW+K+LPGFRNL
Sbjct: 683 LIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNL 742
Query: 198 HVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMR 257
H+DDQ+ +IQYSWM LMVF +GWRS+ +V+ +MLYFAPDL+ NE RM +S YS C+ M
Sbjct: 743 HIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMW 802
Query: 258 HLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKN 317
+ QEF LQ++ +EFLCMK LLL + IP++GL++Q F+E+R +YI+EL + I ++K
Sbjct: 803 QIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKG 862
Query: 318 PTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILS 377
S S+RFYQLTKLLD++ + ++LH + + I+S +SV+FPEMM+E+I+ Q+PKIL+
Sbjct: 863 VVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILA 922
Query: 378 GKVKPIYFH 386
G VKP+ FH
Sbjct: 923 GMVKPLLFH 931
>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
sapiens]
Length = 984
Score = 394 bits (1011), Expect = e-109
Identities = 203/388 (52%), Positives = 256/388 (65%), Gaps = 29/388 (7%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
P K CL+CGDEASGCHYG +TCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+C
Sbjct: 599 PSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 658
Query: 84 RLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTT---------SPTEETT--------- 125
RL+KC +AGM LGARK KKLG LK E + SP E TT
Sbjct: 659 RLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIAPAKEPS 718
Query: 126 -------QKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGE 178
Q T+S P + VLE IEP +V AG+D+++PD+ LLS+LN L
Sbjct: 719 VNTALVPQLSTISRA----LTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAG 774
Query: 179 RQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV 238
+Q++ VVKWAK LPGF+NL ++DQ+ +IQYSWM L FA+ WRS+ + NS+ LYFAPDLV
Sbjct: 775 KQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLV 834
Query: 239 FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDE 298
FNE +MH+S MY C M +S +F LQ+T +E+ MK LLL S IP DGLK+Q F+E
Sbjct: 835 FNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEE 894
Query: 299 LRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSV 358
+R NYIKEL +++ N +RFYQLTKLLDS+ + +L +F F +SH + V
Sbjct: 895 MRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKV 954
Query: 359 DFPEMMAEIISVQVPKILSGKVKPIYFH 386
+FP M+ EIIS Q+PK+ SG KP+YFH
Sbjct: 955 EFPAMLVEIISDQLPKVESGNAKPLYFH 982
>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-109
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 23 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 82
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 83 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 139
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 140 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 260 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 319
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 320 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 379
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 380 VKPIYFH 386
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-109
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 23 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 82
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 83 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 139
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 140 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 260 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 319
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 320 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 379
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 380 VKPIYFH 386
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-109
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 23 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 82
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 83 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 139
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 140 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 260 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 319
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 320 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 379
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 380 VKPIYFH 386
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-109
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 23 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 82
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 83 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 139
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 140 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 260 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 319
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 320 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 379
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 380 VKPIYFH 386
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 391 bits (1005), Expect = e-109
Identities = 192/367 (52%), Positives = 254/367 (69%), Gaps = 10/367 (2%)
Query: 23 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 82
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 83 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 139
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 140 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 260 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 319
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 320 SCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGK 379
+RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 QNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGN 768
Query: 380 VKPIYFH 386
+K + FH
Sbjct: 769 IKKLLFH 775
>gi|66528677 nuclear receptor subfamily 3, group C, member 1 isoform
gamma [Homo sapiens]
Length = 778
Score = 389 bits (999), Expect = e-108
Identities = 193/368 (52%), Positives = 255/368 (69%), Gaps = 11/368 (2%)
Query: 23 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQ-KYLCASRNDCTIDKFRRKNCP 81
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+Q YLCA RNDC IDK RRKNCP
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRNDCIIDKIRRKNCP 475
Query: 82 SCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYEC 138
+CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 ACRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQL 529
Query: 139 QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLH 198
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH
Sbjct: 530 TPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLH 589
Query: 199 VDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRH 258
+DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M +
Sbjct: 590 LDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLY 649
Query: 259 LSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNP 318
+S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N
Sbjct: 650 VSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNS 709
Query: 319 TSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSG 378
+ +RFYQLTKLLDS+ + L + F + M S++FPEM+AEII+ Q+PK +G
Sbjct: 710 SQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNG 768
Query: 379 KVKPIYFH 386
+K + FH
Sbjct: 769 NIKKLLFH 776
>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
beta [Homo sapiens]
Length = 742
Score = 354 bits (908), Expect = 9e-98
Identities = 173/316 (54%), Positives = 224/316 (70%), Gaps = 9/316 (2%)
Query: 23 PPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPS 82
PP K CL+C DEASGCHYG LTCGSCKVFFKRA EG+ YLCA RNDC IDK RRKNCP+
Sbjct: 416 PPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPA 475
Query: 83 CRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQ 139
CR RKC +AGM L ARK KK + +G +TT ++ET++ T+ +
Sbjct: 476 CRYRKCLQAGMNLEARKTKK------KIKGIQQATTGVSQETSENPGNKTIVPATLPQLT 529
Query: 140 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
P +++LE IEP V+ AG+D++ PDS ++++LN LG RQ++ VKWAKA+PGFRNLH+
Sbjct: 530 PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DDQM ++QYSWM LM FA+GWRS+ ++ +L FAPDL+ NE RM MY QC M ++
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 260 SQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPT 319
S E LQ++ +E+LCMK LLL S +P DGLK+Q+ FDE+RM YIKEL + I + N +
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSS 709
Query: 320 SCSRRFYQLTKLLDSV 335
+RFYQLTKLLDS+
Sbjct: 710 QNWQRFYQLTKLLDSM 725
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 158 bits (400), Expect = 7e-39
Identities = 97/333 (29%), Positives = 165/333 (49%), Gaps = 37/333 (11%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
Query: 88 CYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS-------PTEETTQKLTVS 131
CYE GM G + + G L+ + GE S P+ ++ +
Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
Query: 132 HIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKAL 191
+ ++ L EP ++ + +D +P S A+++ L L +R+LVH++ WAK +
Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRV 364
Query: 192 PGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYS 251
PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+ + R
Sbjct: 365 PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLLD-------RNQG 415
Query: 252 QCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPVDGLKNQKFFDEL 299
+CV + S F + + +EF+C+K+++L + LK+ + D +
Sbjct: 416 KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI 475
Query: 300 RMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 332
K D +I K + ++ +L +LL
Sbjct: 476 HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 158 bits (400), Expect = 7e-39
Identities = 97/333 (29%), Positives = 165/333 (49%), Gaps = 37/333 (11%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
Query: 88 CYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS-------PTEETTQKLTVS 131
CYE GM G + + G L+ + GE S P+ ++ +
Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
Query: 132 HIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKAL 191
+ ++ L EP ++ + +D +P S A+++ L L +R+LVH++ WAK +
Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRV 364
Query: 192 PGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYS 251
PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+ + R
Sbjct: 365 PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLLD-------RNQG 415
Query: 252 QCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPVDGLKNQKFFDEL 299
+CV + S F + + +EF+C+K+++L + LK+ + D +
Sbjct: 416 KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI 475
Query: 300 RMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 332
K D +I K + ++ +L +LL
Sbjct: 476 HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 158 bits (400), Expect = 7e-39
Identities = 97/333 (29%), Positives = 165/333 (49%), Gaps = 37/333 (11%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
Query: 88 CYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS-------PTEETTQKLTVS 131
CYE GM G + + G L+ + GE S P+ ++ +
Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
Query: 132 HIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKAL 191
+ ++ L EP ++ + +D +P S A+++ L L +R+LVH++ WAK +
Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRV 364
Query: 192 PGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYS 251
PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+ + R
Sbjct: 365 PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLLD-------RNQG 415
Query: 252 QCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPVDGLKNQKFFDEL 299
+CV + S F + + +EF+C+K+++L + LK+ + D +
Sbjct: 416 KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI 475
Query: 300 RMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 332
K D +I K + ++ +L +LL
Sbjct: 476 HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 158 bits (400), Expect = 7e-39
Identities = 97/333 (29%), Positives = 165/333 (49%), Gaps = 37/333 (11%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
Query: 88 CYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS-------PTEETTQKLTVS 131
CYE GM G + + G L+ + GE S P+ ++ +
Sbjct: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
Query: 132 HIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKAL 191
+ ++ L EP ++ + +D +P S A+++ L L +R+LVH++ WAK +
Sbjct: 305 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRV 364
Query: 192 PGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYS 251
PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+ + R
Sbjct: 365 PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLLD-------RNQG 415
Query: 252 QCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPVDGLKNQKFFDEL 299
+CV + S F + + +EF+C+K+++L + LK+ + D +
Sbjct: 416 KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI 475
Query: 300 RMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 332
K D +I K + ++ +L +LL
Sbjct: 476 HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 158 bits (399), Expect = 9e-39
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 141
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
Query: 142 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 201
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
Query: 202 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 255
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Query: 256 --MRHLSQEFGWLQITPQEFLCMKALLLFS 283
+ + F L++ +E+LC+KA++L +
Sbjct: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 158 bits (399), Expect = 9e-39
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 141
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
Query: 142 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 201
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
Query: 202 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 255
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Query: 256 --MRHLSQEFGWLQITPQEFLCMKALLLFS 283
+ + F L++ +E+LC+KA++L +
Sbjct: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
Length = 530
Score = 158 bits (399), Expect = 9e-39
Identities = 87/270 (32%), Positives = 146/270 (54%), Gaps = 25/270 (9%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQ------KLTVSHIEGYECQPI 141
CYE GM + ++ G ++ + A + + ++ ++ + +
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQL 268
Query: 142 FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDD 201
L +LEA P V+ + + P + A+++ SL +L +++LVH++ WAK +PGF L + D
Sbjct: 269 VLTLLEAEPPHVLIS--RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFD 326
Query: 202 QMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR------ 255
Q+ +++ WM +++ + WRS + L FAPDLV + R +CV
Sbjct: 327 QVRLLESCWMEVLMMGLMWRSIDHPGK--LIFAPDLVLD-------RDEGKCVEGILEIF 377
Query: 256 --MRHLSQEFGWLQITPQEFLCMKALLLFS 283
+ + F L++ +E+LC+KA++L +
Sbjct: 378 DMLLATTSRFRELKLQHKEYLCVKAMILLN 407
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 147 bits (371), Expect = 2e-35
Identities = 86/262 (32%), Positives = 135/262 (51%), Gaps = 6/262 (2%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N+C I K RRK C +C
Sbjct: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
Query: 84 RLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI 141
R KC GM +L ++ G K + E P L V+ P+
Sbjct: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
Query: 142 --FLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
++ L +EP + A D PD +++L +L +R++V + WAK++PGF +L +
Sbjct: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DQM+V+Q WM ++V + RS + L FA DLV +E + + + L
Sbjct: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
Query: 260 SQEFGWLQITPQEFLCMKALLL 281
+ L++ +E++ +KAL L
Sbjct: 313 VRRLQALRLEREEYVLLKALAL 334
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 146 bits (368), Expect = 4e-35
Identities = 84/267 (31%), Positives = 144/267 (53%), Gaps = 25/267 (9%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N+C I K RRK+C +C
Sbjct: 101 PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQAC 160
Query: 84 RLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TSPTEETTQKLTVSHIE 134
R KC + GM +L ++ G K + +A ++ P ++ K+ VSH
Sbjct: 161 RFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKI-VSH-- 217
Query: 135 GYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGF 194
L EP + A D PDS L++L +L +R+LV ++ WAK +PGF
Sbjct: 218 -----------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGF 266
Query: 195 RNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCV 254
L + DQM+++Q +WM +++ + +RS + + L +A D + +E + + +
Sbjct: 267 STLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNN 324
Query: 255 RMRHLSQEFGWLQITPQEFLCMKALLL 281
+ L +++ +++ +EF+ +KA+ L
Sbjct: 325 AILQLVKKYKSMKLEKEEFVTLKAIAL 351
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 146 bits (368), Expect = 4e-35
Identities = 84/267 (31%), Positives = 144/267 (53%), Gaps = 25/267 (9%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N+C I K RRK+C +C
Sbjct: 101 PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQAC 160
Query: 84 RLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TSPTEETTQKLTVSHIE 134
R KC + GM +L ++ G K + +A ++ P ++ K+ VSH
Sbjct: 161 RFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKI-VSH-- 217
Query: 135 GYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGF 194
L EP + A D PDS L++L +L +R+LV ++ WAK +PGF
Sbjct: 218 -----------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGF 266
Query: 195 RNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCV 254
L + DQM+++Q +WM +++ + +RS + + L +A D + +E + + +
Sbjct: 267 STLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNN 324
Query: 255 RMRHLSQEFGWLQITPQEFLCMKALLL 281
+ L +++ +++ +EF+ +KA+ L
Sbjct: 325 AILQLVKKYKSMKLEKEEFVTLKAIAL 351
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 146 bits (368), Expect = 4e-35
Identities = 84/267 (31%), Positives = 144/267 (53%), Gaps = 25/267 (9%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N+C I K RRK+C +C
Sbjct: 124 PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQAC 183
Query: 84 RLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TSPTEETTQKLTVSHIE 134
R KC + GM +L ++ G K + +A ++ P ++ K+ VSH
Sbjct: 184 RFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKI-VSH-- 240
Query: 135 GYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGF 194
L EP + A D PDS L++L +L +R+LV ++ WAK +PGF
Sbjct: 241 -----------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGF 289
Query: 195 RNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCV 254
L + DQM+++Q +WM +++ + +RS + + L +A D + +E + + +
Sbjct: 290 STLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNN 347
Query: 255 RMRHLSQEFGWLQITPQEFLCMKALLL 281
+ L +++ +++ +EF+ +KA+ L
Sbjct: 348 AILQLVKKYKSMKLEKEEFVTLKAIAL 374
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 146 bits (368), Expect = 4e-35
Identities = 84/267 (31%), Positives = 144/267 (53%), Gaps = 25/267 (9%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N+C I K RRK+C +C
Sbjct: 101 PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQAC 160
Query: 84 RLRKCYEAGMTLGARKLKKL--GNLKLQEEGEASST-------TSPTEETTQKLTVSHIE 134
R KC + GM +L ++ G K + +A ++ P ++ K+ VSH
Sbjct: 161 RFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKI-VSH-- 217
Query: 135 GYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGF 194
L EP + A D PDS L++L +L +R+LV ++ WAK +PGF
Sbjct: 218 -----------LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGF 266
Query: 195 RNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCV 254
L + DQM+++Q +WM +++ + +RS + + L +A D + +E + + +
Sbjct: 267 STLSLADQMSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNN 324
Query: 255 RMRHLSQEFGWLQITPQEFLCMKALLL 281
+ L +++ +++ +EF+ +KA+ L
Sbjct: 325 AILQLVKKYKSMKLEKEEFVTLKAIAL 351
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 144 bits (362), Expect = 2e-34
Identities = 82/262 (31%), Positives = 137/262 (52%), Gaps = 15/262 (5%)
Query: 24 PQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSC 83
P++ CL+CGD ASG HYG +C +CK FFKR +G +Y C + N+C I K RRK+C +C
Sbjct: 99 PKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQAC 158
Query: 84 RLRKCYEAGMTLGARKLKKL----GNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQ 139
R KC + GM +L ++ K + + E+S S K ++ I Y
Sbjct: 159 RFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSY--- 215
Query: 140 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHV 199
L EP + A P+ L++L +L +R+LV ++ WAK +PGF +L +
Sbjct: 216 ------LLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSL 269
Query: 200 DDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHL 259
DQM+++Q +WM +++ + +RS + L +A D + +E + + + L
Sbjct: 270 GDQMSLLQSAWMEILILGIVYRSLPYDDK--LVYAEDYIMDEEHSRLAGLLELYRAILQL 327
Query: 260 SQEFGWLQITPQEFLCMKALLL 281
+ + L++ +EF+ +KAL L
Sbjct: 328 VRRYKKLKVEKEEFVTLKALAL 349
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 117 bits (292), Expect = 2e-26
Identities = 79/264 (29%), Positives = 123/264 (46%), Gaps = 9/264 (3%)
Query: 25 QKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCR 84
Q C++CGD++SG HYG TC CK FFKR+ Y C S DC ID+ R C CR
Sbjct: 53 QVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCR 112
Query: 85 LRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI--F 142
L+KC+ GM ++ + G + G ++++ + S + + QP+
Sbjct: 113 LKKCFRVGM---RKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSEL 169
Query: 143 LNVLEAIEPGVVCAGHDNNQPDSFAALLSSLN--ELGERQLVHVVKWAKALPGFRNLHVD 200
+ L EP AG + A+L N EL R L V+WA+ P F L V
Sbjct: 170 IAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVA 229
Query: 201 DQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHL 259
DQ+A+++ SW L V ++ +++ L A L ++ + VR +
Sbjct: 230 DQVALLRLSWSELFVLNAA-QAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQ 288
Query: 260 SQEFGWLQITPQEFLCMKALLLFS 283
+ G LQ+ E+ C+KA+ LF+
Sbjct: 289 VDKLGRLQVDSAEYGCLKAIALFT 312
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 116 bits (291), Expect = 3e-26
Identities = 96/328 (29%), Positives = 149/328 (45%), Gaps = 25/328 (7%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C ICGD +SG HYG +C CK FFKR Y C DC IDK +R C CR +K
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLE 147
C GM A + ++ K + E E ST+S E+ + V I L
Sbjct: 195 CLAMGMKREAVQEERQRG-KDRNENEVESTSSANED----MPVERI---------LEAEL 240
Query: 148 AIEPGVVCAGHDNN--QPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAV 205
A+EP N P S ++++ + ++QL +V+WAK +P F L +DDQ+ +
Sbjct: 241 AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL 300
Query: 206 IQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHLSQEFG 264
++ W L++ + RS + +L A L + H + + + R + L +
Sbjct: 301 LRAGWNELLIASFSHRSIAVKDGILL--ATGLHVHRNSAHSAGVGAIFDRVLTELVSKMR 358
Query: 265 WLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRR 324
+Q+ E C++A++LF+ GL N + LR L+ CK K P R
Sbjct: 359 DMQMDKTELGCLRAIVLFN-PDSKGLSNPAEVEALREKVYASLEAY--CKHKYPEQ-PGR 414
Query: 325 FYQLTKLLDSVQPIAREL--HQFTFDLL 350
F +L L +++ I + H F F L+
Sbjct: 415 FAKLLLRLPALRSIGLKCLEHLFFFKLI 442
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 116 bits (291), Expect = 3e-26
Identities = 90/329 (27%), Positives = 152/329 (46%), Gaps = 20/329 (6%)
Query: 25 QKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCR 84
++ C ICGD +SG HYG +C CK FFKR Y C DCT+DK +R C CR
Sbjct: 202 KRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCR 261
Query: 85 LRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLN 144
+KC GM A + ++ +GE + +P E ++ + L
Sbjct: 262 YQKCLATGMKREAVQEERQRGKDKDGDGEGAG-GAPEEMPVDRILEAE----------LA 310
Query: 145 VLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMA 204
V + + GV G S ++++ + ++QL +V+WAK +P F +L +DDQ+
Sbjct: 311 VEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVI 370
Query: 205 VIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHLSQEF 263
+++ W L++ + RS +V +L A L + H + + + R + L +
Sbjct: 371 LLRAGWNELLIASFSHRSI-DVRDGIL-LATGLHVHRNSAHSAGVGAIFDRVLTELVSKM 428
Query: 264 GWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSR 323
+++ E C++A++LF+ GL N + LR L+ CK+K P
Sbjct: 429 RDMRMDKTELGCLRAIILFN-PDAKGLSNPSEVEVLREKVYASLETY--CKQKYPEQ-QG 484
Query: 324 RFYQLTKLLDSVQPIAREL--HQFTFDLL 350
RF +L L +++ I + H F F L+
Sbjct: 485 RFAKLLLRLPALRSIGLKCLEHLFFFKLI 513
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 116 bits (290), Expect = 4e-26
Identities = 95/328 (28%), Positives = 150/328 (45%), Gaps = 28/328 (8%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C ICGD +SG HYG +C CK FFKR Y C DC IDK +R C CR +K
Sbjct: 139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQK 198
Query: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI--FLNV 145
C GM A +QEE + S + +E G+E P+ L
Sbjct: 199 CLVMGMKREA----------VQEERQRSRERAESEAECA------TSGHEDMPVERILEA 242
Query: 146 LEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAV 205
A+EP G D N +S ++++ ++QL +V+WAK +P F +L ++DQ+ +
Sbjct: 243 ELAVEPKTESYG-DMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVIL 301
Query: 206 IQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVR-MRHLSQEFG 264
++ W L++ + RS + + +L A L + H + + S R + L +
Sbjct: 302 LRAGWNELLIASFSHRSVSVQDGILL--ATGLHVHRSSAHSAGVGSIFDRVLTELVSKMK 359
Query: 265 WLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRR 324
+Q+ E C++A++LF+ GL N + LR L+ K+K P R
Sbjct: 360 DMQMDKSELGCLRAIVLFN-PDAKGLSNPSEVETLREKVYATLEAY--TKQKYPEQ-PGR 415
Query: 325 FYQLTKLLDSVQPIAREL--HQFTFDLL 350
F +L L +++ I + H F F L+
Sbjct: 416 FAKLLLRLPALRSIGLKCLEHLFFFKLI 443
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 111 bits (278), Expect = 1e-24
Identities = 76/268 (28%), Positives = 124/268 (46%), Gaps = 36/268 (13%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C++CGD++SG HYG TC CK FFKR+ Y C + +C ID+ R C CRL+K
Sbjct: 79 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKK 138
Query: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPI---FLN 144
C + GM + E PT+ T + +++ + C +++
Sbjct: 139 CLKVGM---------------RREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYIS 183
Query: 145 VLEAIEPGVVCA-GHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQM 203
+L EP G QP++ + ++ EL R L V+WA+ +P F +L + DQ+
Sbjct: 184 LLLRAEPYPTSRFGSQCMQPNNIMG-IENICELAARMLFSAVEWARNIPFFPDLQITDQV 242
Query: 204 AVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCV--RMRHLS- 260
A+++ +W L V S L+ AP L +H S M + V M H+
Sbjct: 243 ALLRLTWSELFVLNAAQCSMP------LHVAPLLA--AAGLHASPMSADRVVAFMDHIRI 294
Query: 261 -----QEFGWLQITPQEFLCMKALLLFS 283
++ L + E+ C+KA++LF+
Sbjct: 295 FQEQVEKLKALHVDSAEYSCLKAIVLFT 322
>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
Length = 445
Score = 109 bits (272), Expect = 5e-24
Identities = 87/320 (27%), Positives = 146/320 (45%), Gaps = 34/320 (10%)
Query: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
C ICGD A+G HYGA +C CK FF+R+ Y C C +DK +R C CRLRK
Sbjct: 49 CAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRK 108
Query: 88 CYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLE 147
C+ AGM A +Q E + ST T + + +++ + E +
Sbjct: 109 CFRAGMKKEA----------VQNERDRISTRRSTFDGSNIPSINTLAQAE--------VR 150
Query: 148 AIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQ 207
+ + V G + A + + E ++QL+ +V+WAK +P F L +DDQ+A+++
Sbjct: 151 SRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLR 210
Query: 208 YSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRH-----LSQE 262
++ RS M+Y L+ N Y +H++ + R+ + L +
Sbjct: 211 AHAGEHLLLGATKRS-------MMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRP 263
Query: 263 FGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCS 322
F +QI E+ C+KA++ F GL + +R L+ I ++ +
Sbjct: 264 FQEIQIDDNEYACLKAIVFFD-PDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRG-- 320
Query: 323 RRFYQLTKLLDSVQPIAREL 342
RF +L LL ++Q I ++
Sbjct: 321 -RFGELLLLLPTLQSITWQM 339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.137 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,889,565
Number of Sequences: 37866
Number of extensions: 630664
Number of successful extensions: 2214
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1935
Number of HSP's gapped (non-prelim): 173
length of query: 388
length of database: 18,247,518
effective HSP length: 104
effective length of query: 284
effective length of database: 14,309,454
effective search space: 4063884936
effective search space used: 4063884936
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.