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Search of human proteins with 58533172
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58533172 zinc finger, matrin type 1 isoform 3 [Homo sapiens]
(467 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens] 959 0.0
gi|58533172 zinc finger, matrin type 1 isoform 3 [Homo sapiens] 959 0.0
gi|7706156 lysine-rich coiled-coil 1 [Homo sapiens] 337 2e-92
gi|168229156 NFKB activating protein [Homo sapiens] 62 9e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 57 4e-08
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 55 1e-07
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 55 1e-07
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 55 2e-07
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 54 3e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 54 3e-07
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 52 9e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 52 9e-07
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 52 2e-06
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 51 3e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 51 3e-06
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 50 3e-06
gi|27883882 P18SRP protein [Homo sapiens] 50 4e-06
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 50 4e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 49 1e-05
gi|151301228 formin binding protein 3 [Homo sapiens] 49 1e-05
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 49 1e-05
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 49 1e-05
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 48 2e-05
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 47 3e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 47 3e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 47 3e-05
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 47 3e-05
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 47 3e-05
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 47 3e-05
>gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens]
Length = 638
Score = 959 bits (2480), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MRTYVCHICSIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQ 60
MRTYVCHICSIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQ
Sbjct: 172 MRTYVCHICSIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQ 231
Query: 61 KARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAME 120
KARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAME
Sbjct: 232 KARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAME 291
Query: 121 KQLPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRM 180
KQLPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRM
Sbjct: 292 KQLPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRM 351
Query: 181 CEQRFSHEASQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPK 240
CEQRFSHEASQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPK
Sbjct: 352 CEQRFSHEASQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPK 411
Query: 241 TCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLP 300
TCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLP
Sbjct: 412 TCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLP 471
Query: 301 AHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQ 360
AHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQ
Sbjct: 472 AHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQ 531
Query: 361 AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSG 420
AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSG
Sbjct: 532 AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSG 591
Query: 421 KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF 467
KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF
Sbjct: 592 KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF 638
>gi|58533172 zinc finger, matrin type 1 isoform 3 [Homo sapiens]
Length = 467
Score = 959 bits (2480), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MRTYVCHICSIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQ 60
MRTYVCHICSIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQ
Sbjct: 1 MRTYVCHICSIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQ 60
Query: 61 KARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAME 120
KARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAME
Sbjct: 61 KARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAME 120
Query: 121 KQLPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRM 180
KQLPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRM
Sbjct: 121 KQLPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRM 180
Query: 181 CEQRFSHEASQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPK 240
CEQRFSHEASQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPK
Sbjct: 181 CEQRFSHEASQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPK 240
Query: 241 TCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLP 300
TCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLP
Sbjct: 241 TCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLP 300
Query: 301 AHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQ 360
AHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQ
Sbjct: 301 AHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQ 360
Query: 361 AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSG 420
AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSG
Sbjct: 361 AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSG 420
Query: 421 KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF 467
KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF
Sbjct: 421 KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF 467
>gi|7706156 lysine-rich coiled-coil 1 [Homo sapiens]
Length = 259
Score = 337 bits (863), Expect = 2e-92
Identities = 169/257 (65%), Positives = 203/257 (78%), Gaps = 2/257 (0%)
Query: 213 HSKRTYDSFQDELEDYIKVQKARGLEPKTCFRKIGDSSVETHRNREMVDVRPRHRMLEQK 272
HSK+TYDSFQDELEDYIKVQKARGLEPKTCFRK+ +ET + V+ RP +RM +Q+
Sbjct: 3 HSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFDQR 62
Query: 273 LPCETFQTYSGPYSISQVVENQLPHCLPAHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQ 332
LP ET QTY +I Q VEN+LP LPAHDS+ RLDS+SYCQ TRDCF EKPVPL+ NQ
Sbjct: 63 LPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNFNQ 122
Query: 333 QENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKK 392
QE GS+ VE VYKH SS+N+T+ HQA HKQ HQKRKRH EEG+E+ E+E+SKHKRKK
Sbjct: 123 QEYICGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRHPEEGREKSEEERSKHKRKK 182
Query: 393 SYEDTDLDKDKSIRQRKREE--DRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSV 450
S E+ DLDK KSI+++K E + V VS+ KLK+RK+KKS DV S+KEERK K+KK+
Sbjct: 183 SCEEIDLDKHKSIQRKKTEVEIETVHVSTEKLKNRKEKKSRDVVSKKEERKRTKKKKEQG 242
Query: 451 EERTEEEMLWDESILGF 467
+ERTEEEMLWD+SILGF
Sbjct: 243 QERTEEEMLWDQSILGF 259
Score = 121 bits (304), Expect = 1e-27
Identities = 73/165 (44%), Positives = 98/165 (59%), Gaps = 23/165 (13%)
Query: 123 LPHSKKTYDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRMCE 182
+ HSKKTYDSFQDELEDYIKVQKARGL+PKTCFRKM+ + ++T GY+ V+S P RM +
Sbjct: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
Query: 183 QRFSHEASQTYQRPYHI-SPVESQLPQWLPTHSKR-----------TYDSFQDE------ 224
QR E QTY R +I VE++LPQWLP H R T D F ++
Sbjct: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDSRLRLDSLSYCQFTRDCFSEKPVPLNF 120
Query: 225 -LEDYIKVQKARGLEPKTCFRKIGDSSVETHR--NREMVDVRPRH 266
++YI + G+E + D+S TH+ ++++ R RH
Sbjct: 121 NQQEYI--CGSHGVEHRVYKHFSSDNSTSTHQASHKQIHQKRKRH 163
Score = 106 bits (264), Expect = 5e-23
Identities = 53/94 (56%), Positives = 67/94 (71%)
Query: 39 VKNSRKTQDSYQNECADYINVQKARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFE 98
+K+S+KT DS+Q+E DYI VQKARGLE KTCFRKM+ LET Y+ V+SRP +RMF+
Sbjct: 1 MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMKGDYLETCGYKGEVNSRPTYRMFD 60
Query: 99 QRLPFETFRTYAAPYNISQAMEKQLPHSKKTYDS 132
QRLP ET +TY NI Q +E +LP +DS
Sbjct: 61 QRLPSETIQTYPRSCNIPQTVENRLPQWLPAHDS 94
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 62.4 bits (150), Expect = 9e-10
Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 14/184 (7%)
Query: 281 YSGPYSISQVVENQLPHCLPAHDSKQRLDSISYCQLT-RDCFPEKPVPLSLNQQENNSGS 339
Y G YS + P L K+R +S+ +L+ R+ E P N
Sbjct: 100 YYGSYSRPYGSDKPWPSLL----DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEP 155
Query: 340 YSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDL 399
S E + + +T ++K +K R E K+R +K+ SK K KK ED+D
Sbjct: 156 DSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDS 215
Query: 400 DKDK----SIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTE 455
D D S KR + K K KHR KK +K +K RKE S + ++
Sbjct: 216 DSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKY-----KKKRSKKSRKESSDSSSKESQ 270
Query: 456 EEML 459
EE L
Sbjct: 271 EEFL 274
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 57.4 bits (137), Expect = 3e-08
Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 3/117 (2%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQK--RKRHLEEGKERPEKEQSKHKRKKSYEDTDLD 400
E E K + Q G +++ +K RK E K+R E+++ K ++KK ++ +
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 401 KDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
K++ R+RKR++ R K K + R +K+ KE R+ +KE+KK ++ E +
Sbjct: 151 KERGKRERKRKK-RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Score = 57.0 bits (136), Expect = 4e-08
Identities = 28/98 (28%), Positives = 56/98 (57%), Gaps = 2/98 (2%)
Query: 360 QAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSS 419
+ G K+K +++KR E GKER K + + K++K + + K K ++++ + R +
Sbjct: 57 ERGKKEKKKRKKR--ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRER 114
Query: 420 GKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
K K RK+++ + + +RK R++KK+ E + E+E
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Score = 54.7 bits (130), Expect = 2e-07
Identities = 31/108 (28%), Positives = 62/108 (57%), Gaps = 4/108 (3%)
Query: 353 ENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSK---HKRKKSYEDTDLDKDKSIRQRK 409
E + + ++K +KR+R +E K+R ++E+ K KRK+ + ++K R+RK
Sbjct: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
Query: 410 RE-EDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+E + R + G+ + +KKK+ + E ++R+ RK KK+ ++R +E
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Score = 53.9 bits (128), Expect = 3e-07
Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDL-----DKDKSIRQRKREEDRVKVS 418
K++ +KRK ++ KER EKE+ K K++K + K K R+ + E++ +
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 419 SGKLKHRKKKKSHDVPSEKEE-RKHRKEKKKSVEERTEE 456
+ K RKKK+ + EKE ++ RK KK+ EER ++
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171
Score = 53.5 bits (127), Expect = 4e-07
Identities = 30/115 (26%), Positives = 59/115 (51%), Gaps = 10/115 (8%)
Query: 353 ENNTADHQAGHKQKHQK-RKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD--------- 402
E + + K++ +K R++ +E K+R K++ + +RKK E + +++
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 403 KSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
K R++KR ++R + + RK+KK EK+ ++RKE+KK E + E
Sbjct: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
Score = 52.8 bits (125), Expect = 7e-07
Identities = 28/96 (29%), Positives = 56/96 (58%), Gaps = 2/96 (2%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRK--REEDRVKVSSGK 421
+++ +KR+R E +ER +KE+ K K+++ ++ + + + +QRK RE++R K K
Sbjct: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101
Query: 422 LKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
K +K++ +K+ERK R+ + K ER ++
Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/101 (28%), Positives = 57/101 (56%), Gaps = 14/101 (13%)
Query: 348 KHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQ 407
K EN + K++ +KR++ + KER ++E+ + KRKK E+ + ++++ ++
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK--EEREKKRERNRKE 178
Query: 408 RKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKK 448
RK+E +R K R+++K K+ER+ +KE+KK
Sbjct: 179 RKKERER--------KERRERKK----ERKKERRKKKERKK 207
Score = 48.5 bits (114), Expect = 1e-05
Identities = 26/94 (27%), Positives = 47/94 (50%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLK 423
+ + +K +R E+ K EKE+ + + KK + + R+RKR+E + + K
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 424 HRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
R+K+K E+++R R+ KKK + E E
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Score = 46.2 bits (108), Expect = 6e-05
Identities = 26/88 (29%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Query: 371 KRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQ-RKREEDRVKVSSGKLKHRKKKK 429
+R E KER E+E+ K +R+K + K+K R+ R+R ++R + + K RK+++
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 430 SHDVPSEKEERKHRKEKKKSVEERTEEE 457
+ K+E+K R+ K++ ER +++
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKK 118
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Query: 373 HLEEGKERPEKEQSKHKRKKSYEDTDLDKD-KSIRQRKREEDRVKVSSGKLKHRKKK--- 428
H+ + + E E+ K +R++ + +K+ K R +K ++ R K GK + RK+K
Sbjct: 24 HISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83
Query: 429 KSHDVPSEKEERKHRKEKKK 448
K EKE RK +KEKKK
Sbjct: 84 KQRKERREKERRKRKKEKKK 103
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 3/64 (4%)
Query: 397 TDLDKDKSIRQRKREE---DRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEER 453
T + ++ +R+RE+ +R K + ++KKK KE + RKE++K +ER
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 454 TEEE 457
E+E
Sbjct: 90 REKE 93
Score = 31.6 bits (70), Expect = 1.6
Identities = 19/86 (22%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQK--RKRHLEEGKERPEKEQSKHK 389
++EN + K + + + G +++ +K +K E+ +ER KE+ K +
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183
Query: 390 RKKSYEDTDLDKDKSIRQRK-REEDR 414
+K + ++ K R++K R++DR
Sbjct: 184 ERKERRERKKERKKERRKKKERKKDR 209
Score = 30.8 bits (68), Expect = 2.7
Identities = 16/59 (27%), Positives = 32/59 (54%)
Query: 399 LDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
+ K + R+ +R+++R + K + K++K EK++RK R+ K+ +R E E
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 57.0 bits (136), Expect = 4e-08
Identities = 32/126 (25%), Positives = 68/126 (53%), Gaps = 5/126 (3%)
Query: 333 QENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKK 392
+ G ESE K E + + ++K +KR+R +E K +KE+ + K+++
Sbjct: 46 ETRKEGKKERESERKK----ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 393 SYEDTDLDKDKSIRQRKREEDRVKVSS-GKLKHRKKKKSHDVPSEKEERKHRKEKKKSVE 451
++ ++K R++K +++R + S GK + RK+++ + E+E +K +EK++ +
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
Query: 452 ERTEEE 457
ER + E
Sbjct: 162 ERKKRE 167
Score = 56.2 bits (134), Expect = 6e-08
Identities = 35/117 (29%), Positives = 61/117 (52%), Gaps = 13/117 (11%)
Query: 353 ENNTADHQAGHKQKHQK-RKRHLEEGKERPEKEQSKHKRKKSYE--DTDLDKDKSIRQRK 409
EN + + K+K +K R R +EGKER KE+ K + +K E + +K++ ++RK
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164
Query: 410 R----------EEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+ EE + K + K + +K E++ER+ RK+++K EER +E
Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE 221
Score = 54.7 bits (130), Expect = 2e-07
Identities = 31/103 (30%), Positives = 57/103 (55%), Gaps = 9/103 (8%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLD------KDKSIRQRKREEDRVKV 417
+++ +K++R +E KE EKE+ K K KK T + K++ R+ ++E +R K
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 418 SSGKLKHRKKKKSHD---VPSEKEERKHRKEKKKSVEERTEEE 457
K + RK++K + V ++EERK ++ K++ ER +E
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
Score = 52.0 bits (123), Expect = 1e-06
Identities = 29/112 (25%), Positives = 57/112 (50%), Gaps = 2/112 (1%)
Query: 353 ENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRK--R 410
E + G K++ +RK+ E ++R + + + KR++ ++ ++ K R+RK R
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 411 EEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDE 462
E K K K +KK+K + KE ++ +++++ EER E E +E
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Score = 50.8 bits (120), Expect = 3e-06
Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 353 ENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREE 412
E + + ++K ++RK+ E KER KE+ K +RK+ E + K+K ++RK+ E
Sbjct: 132 ERERKEERKREERKERERKKE-EREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 413 DRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
K + + +++++ +KEERK ++K + R +E
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
Score = 49.3 bits (116), Expect = 7e-06
Identities = 30/103 (29%), Positives = 59/103 (57%), Gaps = 9/103 (8%)
Query: 360 QAGHKQKHQKRKRHLE---EGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREE--DR 414
Q G + + ++R+R +E EGK+ E E+ K +R++ + +K++ + K+E+ +R
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Query: 415 VKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
K + K R++K++ E EE++ RK+K+K RT +E
Sbjct: 91 KKEERERKKRRREKEN----KEGEEKEKRKKKEKKERGRTSKE 129
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 11/140 (7%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSK---H 388
++EN G E E K + + G K++ +K +R EE KER K++ +
Sbjct: 103 EKENKEGE---EKEKRKKKEKKERGRTSKEG-KERERKEERKREERKERERKKEEREKER 158
Query: 389 KRK--KSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEK 446
+RK K E + + + R+ K ++R K + + +K+++ + K+ERK ++E+
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Query: 447 KKSVEERTEEEMLWDESILG 466
KK E + + + W E G
Sbjct: 219 KK--ERQKDRQTNWREKERG 236
Score = 43.5 bits (101), Expect = 4e-04
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 11/132 (8%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEK------EQ 385
+++ G S E + + + K++ ++++R +E K+R K E+
Sbjct: 118 KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177
Query: 386 SKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKE 445
K K +K + ++++ ++RK+E +R K + K RKKK+ +K+ + + +E
Sbjct: 178 RKEKERKERK----KRERNRKERKKERER-KERRERKKERKKKEERKKERQKDRQTNWRE 232
Query: 446 KKKSVEERTEEE 457
K++ ER E +
Sbjct: 233 KERGKRERKERK 244
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 55.1 bits (131), Expect = 1e-07
Identities = 37/107 (34%), Positives = 61/107 (57%), Gaps = 4/107 (3%)
Query: 349 HLSSENNTADHQ--AGHKQKHQKRKRHLEEGKERPEK--EQSKHKRKKSYEDTDLDKDKS 404
H+S E+N A+ Q A ++ K K + L + +E E++K KR+K+ K+K
Sbjct: 284 HISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKE 343
Query: 405 IRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVE 451
+++KREE + V +LK +++K+ V EKE K R+EK+K VE
Sbjct: 344 DKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVE 390
Score = 34.3 bits (77), Expect = 0.25
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRK--REEDRVKVSSGK 421
K K +K + KE+ +KE+ + + KK E+ L K + + K RE++R K+ K
Sbjct: 326 KLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEK 385
Query: 422 LKHRKKKKSHDVPSEKEERKHRKEKKKSVEERT 454
K+ + K P E E KE + +T
Sbjct: 386 RKYVEYLKQWSKPREDMECDDLKELPEPTPVKT 418
Score = 33.1 bits (74), Expect = 0.55
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 370 RKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRK--- 426
RKR E+ KE+ +K + K ++ K E + D SI + +RE+ + S + ++
Sbjct: 636 RKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQ 695
Query: 427 --KKKSHDVPSEKEERKHRKEKKKSVEERTEEEML 459
+ D P + + K + +E T +E +
Sbjct: 696 DMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQI 730
Score = 30.4 bits (67), Expect = 3.6
Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Query: 361 AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTD-LDKDKSIRQRKREEDRVKVSS 419
A ++ ++ H+ + K+ R K+ ++ D L K + ++ E+ ++K
Sbjct: 272 ANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREK 331
Query: 420 GKLKHRKKKKSHDVPSEKEERK----HRKEKKKSVEERTEEE 457
KKK+ D ++EE K + KKK +ER + E
Sbjct: 332 ADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVE 373
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 55.1 bits (131), Expect = 1e-07
Identities = 37/107 (34%), Positives = 61/107 (57%), Gaps = 4/107 (3%)
Query: 349 HLSSENNTADHQ--AGHKQKHQKRKRHLEEGKERPEK--EQSKHKRKKSYEDTDLDKDKS 404
H+S E+N A+ Q A ++ K K + L + +E E++K KR+K+ K+K
Sbjct: 284 HISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKE 343
Query: 405 IRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVE 451
+++KREE + V +LK +++K+ V EKE K R+EK+K VE
Sbjct: 344 DKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVE 390
Score = 34.3 bits (77), Expect = 0.25
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRK--REEDRVKVSSGK 421
K K +K + KE+ +KE+ + + KK E+ L K + + K RE++R K+ K
Sbjct: 326 KLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEK 385
Query: 422 LKHRKKKKSHDVPSEKEERKHRKEKKKSVEERT 454
K+ + K P E E KE + +T
Sbjct: 386 RKYVEYLKQWSKPREDMECDDLKELPEPTPVKT 418
Score = 33.1 bits (74), Expect = 0.55
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 370 RKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRK--- 426
RKR E+ KE+ +K + K ++ K E + D SI + +RE+ + S + ++
Sbjct: 668 RKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQ 727
Query: 427 --KKKSHDVPSEKEERKHRKEKKKSVEERTEEEML 459
+ D P + + K + +E T +E +
Sbjct: 728 DMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQI 762
Score = 30.4 bits (67), Expect = 3.6
Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 5/102 (4%)
Query: 361 AGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTD-LDKDKSIRQRKREEDRVKVSS 419
A ++ ++ H+ + K+ R K+ ++ D L K + ++ E+ ++K
Sbjct: 272 ANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREK 331
Query: 420 GKLKHRKKKKSHDVPSEKEERK----HRKEKKKSVEERTEEE 457
KKK+ D ++EE K + KKK +ER + E
Sbjct: 332 ADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVE 373
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/148 (26%), Positives = 70/148 (47%), Gaps = 15/148 (10%)
Query: 326 VPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQ 385
+P + QE G + S+ ++ S + + + + +K + + G+++ EK
Sbjct: 1143 LPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVF 1202
Query: 386 SKHKRKKSYEDTDLDKDKSIR------QRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEE 439
KHK KK E T+ KD+ R Q K+ + ++ + K KH + K+ EK +
Sbjct: 1203 EKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEK-KHAAEDKAKSKHKEKSD 1261
Query: 440 RKHRKEKK--------KSVEERTEEEML 459
++H KE+K KS+ E+ EEE L
Sbjct: 1262 KEHSKERKSSRSADAEKSLLEKLEEEAL 1289
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/133 (31%), Positives = 62/133 (46%), Gaps = 21/133 (15%)
Query: 350 LSSENN--TADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQ 407
LS+EN H H +K +K + E KE K++ KR K DT+ D +S R+
Sbjct: 678 LSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIK---DTNKDISRSFRE 734
Query: 408 RK------REEDRVKVSSGK------LKHRKKKKSHDVPSEKEERKHRKEKKKSVEE--- 452
K +E +K S K K +KKKS D PS+ E++ KE K S E+
Sbjct: 735 EKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKI 794
Query: 453 -RTEEEMLWDESI 464
+ ++E L E +
Sbjct: 795 FKEDKEKLKKEKV 807
Score = 39.3 bits (90), Expect = 0.008
Identities = 25/92 (27%), Positives = 49/92 (53%), Gaps = 5/92 (5%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQ--RKREEDRVKVSSGK 421
++ H R++ ++G ++ KE++K +R Y++ DKDKS + K ++D+ K
Sbjct: 1001 ERHHPAREKEKKDGPDKERKEKTKPER---YKEKSSDKDKSEKSILEKCQKDKEFDKCFK 1057
Query: 422 LKHRKKKKSHDVPSEKEERKHRKEKKKSVEER 453
K K+K D + +ERK ++ K +E+
Sbjct: 1058 EKKDTKEKHKDTHGKDKERKASLDQGKEKKEK 1089
Score = 33.5 bits (75), Expect = 0.42
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 14/96 (14%)
Query: 375 EEGKERPEKEQSKHKRKKSYEDTDLDK------DKSIRQRKREEDRVKVSSGKLKHRKKK 428
E+ KER + S+ + K+ Y + K DK+ +RK + ++ K G L + KK
Sbjct: 883 EDSKER--RRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKK 940
Query: 429 KSHDVPSEKEER------KHRKEKKKSVEERTEEEM 458
+ + ++ + K R++ + EE EE+
Sbjct: 941 RRESAEAGRDRKDALESCKERRDGRAKPEEAHREEL 976
Score = 33.5 bits (75), Expect = 0.42
Identities = 32/144 (22%), Positives = 59/144 (40%), Gaps = 39/144 (27%)
Query: 358 DHQAGHKQKHQK---RKRHLEEGKER-------------PEKEQSKHKRKKSYEDTDLDK 401
D + HK H K RK L++GKE+ EK+ K ++KS+ D+
Sbjct: 1061 DTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFT 1120
Query: 402 DKSIRQR-----------------------KREEDRVKVSSGKLKHRKKKKSHDVPSEKE 438
D+S R ++EE R +S + + K+ + +KE
Sbjct: 1121 DESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKE 1180
Query: 439 ERKHRKEKKKSVEERTEEEMLWDE 462
R RK++ + R ++E ++++
Sbjct: 1181 PRDRRKDRGAADAGRDKKEKVFEK 1204
Score = 32.0 bits (71), Expect = 1.2
Identities = 28/126 (22%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Query: 344 SEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDK 403
S ++ +N A+ + K+K K ++ +ER K++SK + K + DL +DK
Sbjct: 729 SRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEER--KKKSKDRPSKLEKKNDLKEDK 786
Query: 404 SIRQRKR--EEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWD 461
+++++ +ED+ K+ K K ++ + D K + ++ K S+ + + D
Sbjct: 787 ISKEKEKIFKEDKEKLK--KEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSD 844
Query: 462 ESILGF 467
S F
Sbjct: 845 LSDSSF 850
Score = 30.8 bits (68), Expect = 2.7
Identities = 31/148 (20%), Positives = 58/148 (39%), Gaps = 31/148 (20%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYE------- 395
E E ++H SS + + + K++ ++K E+ KE ++ S K E
Sbjct: 1346 EKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVS 1405
Query: 396 -----DTDLDKDKSIR----QRKREEDRVKVSSGK---------------LKHRKKKKSH 431
D + + DK+I ++K + D + S K LK +KK++ H
Sbjct: 1406 YNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKH 1465
Query: 432 DVPSEKEERKHRKEKKKSVEERTEEEML 459
E+ +HR + +E+L
Sbjct: 1466 REKWRDEKERHRDRHADGLLRHHRDELL 1493
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 53.9 bits (128), Expect = 3e-07
Identities = 29/101 (28%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLK 423
++ + R+R+ + G+ER ++ + + R++ + + + R+RKRE DR + + +
Sbjct: 106 RETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE 165
Query: 424 HRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESI 464
RKK++ +KE +K RKEKKK + R +++ W E I
Sbjct: 166 ERKKER------KKERKKERKEKKKEEKRREDKKRKWGEGI 200
Score = 52.4 bits (124), Expect = 9e-07
Identities = 32/128 (25%), Positives = 64/128 (50%), Gaps = 9/128 (7%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERP---EKEQSKH 388
++EN + + + +H + T + +QK + R+R E ER ++E+ +
Sbjct: 26 ERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQ 85
Query: 389 KRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKK 448
+ +K D + DKD+ R+RKRE DR + ++RK + D +E+E + R+ +++
Sbjct: 86 RERKRQTDRERDKDRD-RERKRETDR-----NRERNRKGGRERDKQTERERDRERERQRQ 139
Query: 449 SVEERTEE 456
ER +
Sbjct: 140 RERERQRQ 147
Score = 45.4 bits (106), Expect = 1e-04
Identities = 33/131 (25%), Positives = 69/131 (52%), Gaps = 11/131 (8%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQK--HQKRKRHLEEGKERP---EKEQS 386
++E + G E E + EN T + + H+Q+ H++R R + KER E+++
Sbjct: 8 KRETDRGK-ETERERDRQRERENQT-ERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
Query: 387 KHKRKKSYEDTDLDKDKSI-RQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKE 445
+ + +++ +T+ +++ R+RKR+ DR + K + R++K+ D E+ + R+
Sbjct: 66 RQRERETERETERQRERQRQRERKRQTDRER---DKDRDRERKRETDRNRERNRKGGRER 122
Query: 446 KKKSVEERTEE 456
K++ ER E
Sbjct: 123 DKQTERERDRE 133
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 365 QKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKH 424
++ ++RKR + GKE E+ + ++++ T+ + R R RE DR + + K
Sbjct: 2 ERQRERKRETDRGKET---ERERDRQRERENQTERENRHRQRDRHRERDR---QTDREKE 55
Query: 425 RKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
R+++K D ++E R+ +++ +R E
Sbjct: 56 RERQKERDRQRQRERETERETERQRERQRQRE 87
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 53.9 bits (128), Expect = 3e-07
Identities = 28/92 (30%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLK 423
K+K +K EE +E E+E+ + KRK+ ++ +K+K + ++ E+ + K K +
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 424 HRKKKKSHDVPSEKEERKHRKEKKKSVEERTE 455
RK+KK + E+EE + +E++K EE+ E
Sbjct: 63 KRKRKKKKE-EEEREEEEEEEEEEKEEEEKEE 93
Score = 53.9 bits (128), Expect = 3e-07
Identities = 29/110 (26%), Positives = 61/110 (55%), Gaps = 5/110 (4%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQS----KHKRKKSYEDTD 398
E+E + + + K+K +++K+ +E ++R EKE+ K KRKK E+ +
Sbjct: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74
Query: 399 LDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKK 448
++++ + ++EE+ K + K +KK++ + EK++++ RK KKK
Sbjct: 75 REEEEEEEEEEKEEEE-KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 14/93 (15%)
Query: 365 QKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKH 424
+K +K+K+ EE +E E E+ + K K E R+ KR+E K + + +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK---------RKEKRKEKEKKKKTKETEK 51
Query: 425 RKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
RK+K+ E+++RK +++KKK EER EEE
Sbjct: 52 RKEKEE-----EEKKRKRKRKKKKEEEEREEEE 79
Score = 50.1 bits (118), Expect = 4e-06
Identities = 27/110 (24%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 348 KHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQ 407
K T + + +++ +++++ E+ KE+ +K+++K K+ ++ + K K R+
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67
Query: 408 RKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
+K+EE+ + + + K+++ EKEE + RK+KKK + EEE
Sbjct: 68 KKKEEEEREEEEEEEEEEKEEE------EKEEGRRRKKKKKRRRKEEEEE 111
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 52.4 bits (124), Expect = 9e-07
Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD 402
E + + E T + + ++R+R + ++R K Q++ +R+ E + + D
Sbjct: 172 ERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG-ERETD 230
Query: 403 KSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDE 462
+ R+R+R+ DR K + R +K+ +KE +K RKEKKK + R +++ W E
Sbjct: 231 RR-RERQRDRDRGKERD---RERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
Query: 463 SI 464
I
Sbjct: 287 GI 288
Score = 43.1 bits (100), Expect = 5e-04
Identities = 25/116 (21%), Positives = 62/116 (53%), Gaps = 3/116 (2%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERP-EKEQSKHKRKKSYEDTDLDK 401
E E ++ E T + ++K + R+R + G+ER ++++ K + +++ +D D +
Sbjct: 106 EKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQR 165
Query: 402 D-KSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+ ++ R+R RE ++ K + + R +++ + E++ + R ++K+ ER E
Sbjct: 166 ETETERERDREREKQKERETE-RDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220
Score = 42.7 bits (99), Expect = 7e-04
Identities = 27/122 (22%), Positives = 59/122 (48%), Gaps = 9/122 (7%)
Query: 345 EVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKS 404
+ +K ++ + ++ ++R R + +ER KE+ ++ + + T++++D+
Sbjct: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
Query: 405 IRQ---RKREEDRVKV-----SSGKLKHRKKKKSHDVPSEKE-ERKHRKEKKKSVEERTE 455
+ R+RE DR + K + R+ +K D E E ER+ +E++K E TE
Sbjct: 127 REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE 186
Query: 456 EE 457
+
Sbjct: 187 RD 188
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 52.4 bits (124), Expect = 9e-07
Identities = 31/101 (30%), Positives = 61/101 (60%), Gaps = 5/101 (4%)
Query: 358 DHQAGHKQKHQKRKRHLEEGKERPEKE-QSKHKRKKSYEDTDLDKDKSIRQRKREEDRVK 416
D++ K+K +K+K+ +E KE+ +K+ SK K E K++ RQ++ EE+R+K
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367
Query: 417 VSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
+L+ + K+ + E+E+R+ +K+K+K +ER ++E
Sbjct: 368 ----RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Score = 39.7 bits (91), Expect = 0.006
Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 30/134 (22%)
Query: 353 ENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLD---KDKSIR--- 406
E+ D A K K +K+ ++ +ER ++++ K K +K E +L+ KD+S +
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKES 272
Query: 407 QRKREEDRVK----VSSGKLK------------------HRKKKKSHDVPSEKEERKHRK 444
QRK EE+ VK V +G + +KKK EKEE++ K
Sbjct: 273 QRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKE--K 330
Query: 445 EKKKSVEERTEEEM 458
EKKK + T + M
Sbjct: 331 EKKKGPSKATVKAM 344
Score = 39.3 bits (90), Expect = 0.008
Identities = 32/128 (25%), Positives = 61/128 (47%), Gaps = 9/128 (7%)
Query: 331 NQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKR 390
N++ + S S+ K S N++ + + Q RK G+++ +K +
Sbjct: 158 NKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRK-----GQKKNQKNKPGPNI 212
Query: 391 KKSYEDTDLD-KDKSIRQRK---REEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEK 446
+ ED D K K++ Q+K +E +R K K K RK K+ ++ + K+++ +KE
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKES 272
Query: 447 KKSVEERT 454
++ EE T
Sbjct: 273 QRKFEEET 280
Score = 39.3 bits (90), Expect = 0.008
Identities = 41/179 (22%), Positives = 82/179 (45%), Gaps = 29/179 (16%)
Query: 294 QLPHCLPAHDSKQRLDSISYCQLTRDCFPEK---PVPLSLNQQENNSGSYSVESEVYKHL 350
++P L + + + ++ + ++ PEK P P+ ++E+ + + E +
Sbjct: 453 KIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEA---M 509
Query: 351 SSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKR 410
+S+ T +K + K H+E KE PE+E+ + + ++ E+++ ++++
Sbjct: 510 ASDEET--------EKVEGNKVHIEV-KENPEEEEEEEEEEEEDEESEEEEEEEGESEGS 560
Query: 411 E--EDRVKVS----SGKLKHRKKKKSHDVPSE--------KEERKHRKEKKKSVEERTE 455
E E+ KVS SGK +K K SE KEER + K K++ + R E
Sbjct: 561 EGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLE 619
Score = 33.5 bits (75), Expect = 0.42
Identities = 20/81 (24%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Query: 382 EKEQSKHKRKKSYEDTDLDKD---KSIRQRKREEDRVKVSSGKLKHR-KKKKSHDVPSEK 437
E ++SK K+KK + D D+D K + + E +K + + + + S+
Sbjct: 36 EPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKD 95
Query: 438 EERKHRKEKKKSVEERTEEEM 458
+++K +K KK+S ++ EE+
Sbjct: 96 KKKKGQKGKKQSFDDNDSEEL 116
Score = 33.1 bits (74), Expect = 0.55
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 44/181 (24%)
Query: 324 KPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEK 383
KP P + E++ S+ +++ K +E + + ++K + RK +E E +K
Sbjct: 207 KPGPNIESGNEDDDASFKIKTVAQK--KAEKKERERKKRDEEKAKLRKLKEKEELETGKK 264
Query: 384 EQSKHKRKK-------------------------------SYEDTDLDKDKSIRQRKR-- 410
+QSK K + + +D + DK K +++K+
Sbjct: 265 DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGE 324
Query: 411 -EEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRK----EKKKSVEE----RTEEEMLWD 461
EE + G K K + KEE + +K E+ K +EE R EEE L
Sbjct: 325 KEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ 384
Query: 462 E 462
E
Sbjct: 385 E 385
Score = 32.3 bits (72), Expect = 0.94
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 11/81 (13%)
Query: 381 PEKEQS----KHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSE 436
PEKE++ + + ++ ED LD +++ +E+ KV K+ K+ P E
Sbjct: 481 PEKEETPPPVEPEEEEDTEDAGLDDWEAMAS---DEETEKVEGNKVHIEVKEN----PEE 533
Query: 437 KEERKHRKEKKKSVEERTEEE 457
+EE + +E+ + EE EEE
Sbjct: 534 EEEEEEEEEEDEESEEEEEEE 554
Score = 31.6 bits (70), Expect = 1.6
Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 18/112 (16%)
Query: 362 GHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSG- 420
G QK K+ EE ++ +K + + + S E D + D+ ++ RK ++ K G
Sbjct: 152 GKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGD-ESDEFLQSRKGQKKNQKNKPGP 210
Query: 421 -------------KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEML 459
K+K +KK+ ++ ERK R E+K + + E+E L
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAE---KKERERKKRDEEKAKLRKLKEKEEL 259
Score = 31.2 bits (69), Expect = 2.1
Identities = 24/113 (21%), Positives = 57/113 (50%), Gaps = 22/113 (19%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLK 423
K++ +++KR EE +R E+ ++K K ++ E ++ K ++ K ++R+K GKL
Sbjct: 352 KEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK--QKEKERKERLK-KEGKLL 408
Query: 424 HRKKKKSH---------------DVPSE----KEERKHRKEKKKSVEERTEEE 457
+ ++++ +VPS+ K+ + +K+K + ++ E +
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESK 461
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 51.6 bits (122), Expect = 2e-06
Identities = 34/127 (26%), Positives = 64/127 (50%), Gaps = 21/127 (16%)
Query: 333 QENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKK 392
+E G + + + SS+++T + ++ K+ +K+K+ +E ++ + KRKK
Sbjct: 123 EEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
Query: 393 SYED-----------TDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERK 441
SY D +D ++D ++++R E+R K K +KKKK K+ +K
Sbjct: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRRCEER---EQAKEKVKKKKK-------KQHKK 232
Query: 442 HRKEKKK 448
H K+KKK
Sbjct: 233 HSKKKKK 239
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 16/129 (12%)
Query: 345 EVYKHLSSENNTADHQAGHKQK-HQKRKRHLEEGKER---------PEKEQSKHKRKKSY 394
EV K L ++ + A ++K ++ K+ LE+ +E+ ++E+ K ++KKS
Sbjct: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
Query: 395 EDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVP------SEKEERKHRKEKKK 448
+ + + + GK + +KK +S+ SE E ++ K+KKK
Sbjct: 103 RSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKK 162
Query: 449 SVEERTEEE 457
S +E +E+
Sbjct: 163 SKDETEKEK 171
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/106 (22%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Query: 351 SSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKR 410
S E + +++ K++ +K+KR ++ R S S D++ ++ K ++RK+
Sbjct: 76 SREKLLSGNESSSKKRERKKKR--KKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKK 133
Query: 411 EEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+++R SS H + +S + +K++ K EK+K V +++
Sbjct: 134 KKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKK 179
Score = 37.4 bits (85), Expect = 0.029
Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 11/112 (9%)
Query: 351 SSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKR 410
SS+++++ + ++K Q ++R ++ + + S H+ + +++ K KS + ++
Sbjct: 110 SSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEK 169
Query: 411 EEDRVKVSSGKLKHRKKKKSHDVPSEKE-------ERKHRKEKKKSVEERTE 455
E+D +S K RKK D P E E + +KK+ EER +
Sbjct: 170 EKDVRSLS----KKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQ 217
Score = 37.4 bits (85), Expect = 0.029
Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 14/121 (11%)
Query: 351 SSENNTADHQAGHKQKHQKRKRHLEEGKERPEKE----QSKHKRKKSYEDTDLDKDKSIR 406
SS++ + + G ++K +K + + E E +S K+KKS ++T+ +KD
Sbjct: 117 SSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSL 176
Query: 407 QRKREE---DRVKVSSGKLKH-------RKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+KR++ D +SS + KKK E+ + K +K+KKK ++ +++
Sbjct: 177 SKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKK 236
Query: 457 E 457
+
Sbjct: 237 K 237
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/61 (29%), Positives = 35/61 (57%), Gaps = 5/61 (8%)
Query: 348 KHLSSENNTA-----DHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD 402
K LSSE+++ D QA K++ ++R++ E+ K++ +K+ KH +KK + K
Sbjct: 188 KPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
Query: 403 K 403
+
Sbjct: 248 R 248
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 50.8 bits (120), Expect = 3e-06
Identities = 27/105 (25%), Positives = 65/105 (61%), Gaps = 7/105 (6%)
Query: 352 SENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKRE 411
S +++ D + ++K ++++R E+ +E+ E+E+ K + K+ + D+DK R++ RE
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVKEKDREK-EREREKEREKEKERGKNKDRDKE-REKDRE 426
Query: 412 EDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+D+ K + R+++K H+ +KE+ K + ++K+ ++R++E
Sbjct: 427 KDKEKD-----REREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 331 NQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKER---PEKEQSK 387
N+++ S+ S + Q+ H+ + R R ++ + R P K++SK
Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 388 --HKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKE 445
+RK DK K R++ +E++RVK + K R+++K + E+ + K R +
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVK-EKDREKEREREKEREKEKERGKNKDRDK 419
Query: 446 KKKSVEERTEEE 457
+++ E+ +E+
Sbjct: 420 EREKDREKDKEK 431
Score = 47.4 bits (111), Expect = 3e-05
Identities = 24/99 (24%), Positives = 56/99 (56%), Gaps = 4/99 (4%)
Query: 359 HQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVS 418
H+ K + +++ R +++ + + K K K+ ++ D +K+ R+R++E ++ K
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE---REREKEREKEK-E 410
Query: 419 SGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
GK K R K++ D +KE+ + R+ +K+ ++R +E+
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Score = 45.8 bits (107), Expect = 8e-05
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 20/153 (13%)
Query: 329 SLNQQENNSGSYSVESEVYKHLSSENNTADHQAGH---KQKHQKRKRHLEEGKERPEKEQ 385
S ++ + S S S+ S N + Q K H+KR + E K R +
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR-SRSH 372
Query: 386 SKHKRKKSYE-----DTDLDKDKSIRQRKREEDRVKVSS-GKLKHRKKKKSHDVPSEKE- 438
S+ KRK + E + +KD+ ++R+RE++R K GK K R K++ D +KE
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDRE-KEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 439 ------ERKHRKE--KKKSVEERTEEEMLWDES 463
E++H K+ K+K E+ E+E D S
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDKEKEREKDRS 464
Score = 45.8 bits (107), Expect = 8e-05
Identities = 36/129 (27%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Query: 322 PEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERP 381
P K S ++++ S S+S + + + E + K + ++R+R E KE+
Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDK---RKDTREKIKEKERVKEKDREKEREREKEREKEK- 409
Query: 382 EKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVK-VSSGKLKHRKKKKSHDVPSEKEER 440
E+ ++K + K+ +D + DK+K R+R+RE++ K K K + K+K + KE
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKD-REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEID 468
Query: 441 KHRKEKKKS 449
+ RK+ KKS
Sbjct: 469 EKRKKDKKS 477
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/94 (31%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSI-RQRKREEDRVKV-SSGK 421
K+K ++++R E+ +E+ EKE+ K+K + + D +KDK R+R+RE++ K K
Sbjct: 391 KEKDREKEREREKEREK-EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 422 LKHRKKKKSHDVPSEKE-ERKHRKEKKKSVEERT 454
K + K+K + KE + K +K+KK R+
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 483
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 10/123 (8%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD 402
E + K E + K K + ++R + K++ EK++ + + K+ +D D +K+
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-EKDREREREKEHEKDRDKEKE 450
Query: 403 KSI-RQRKREEDRVKVSSGKLKHRKKKK--------SHDVPSEKEERKHRKEKKKSVEER 453
K ++++RE+DR K K K KK + S S ER+ R+ + S R
Sbjct: 451 KEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPR 510
Query: 454 TEE 456
T +
Sbjct: 511 TSK 513
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/183 (23%), Positives = 72/183 (39%), Gaps = 29/183 (15%)
Query: 304 SKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGH 363
S+ R S + TR+ EK ++++ E E + + + + +
Sbjct: 367 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDRE 426
Query: 364 KQKHQKRKRHLEEGKER-----PEKEQSKHKRKKSYEDTDLD----KDK----------- 403
K K + R+R E+ E+ EKEQ K K ++ ++D KDK
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 486
Query: 404 ------SIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKS---VEERT 454
S R+R+R R S + K+KS PS + K K+++K + ER
Sbjct: 487 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR 546
Query: 455 EEE 457
E E
Sbjct: 547 ERE 549
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 327 PLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQS 386
P S E G + SS++++ ++ K + + R K+R +
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 387 KHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEK 446
KR KS E + R R D+ K + K+K +++ K D E+E K R+++
Sbjct: 355 HKKRSKSRER------RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKE 408
Query: 447 KKSVEERTEEE 457
K+ + + ++
Sbjct: 409 KERGKNKDRDK 419
Score = 37.0 bits (84), Expect = 0.038
Identities = 28/152 (18%), Positives = 59/152 (38%), Gaps = 12/152 (7%)
Query: 318 RDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKH--QKRKRHLE 375
+D EK ++ S ++ + K S + A + + ++R+R
Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS 502
Query: 376 EGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPS 435
R + KRK S + ++K ++R++E D + + + +KS +
Sbjct: 503 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 562
Query: 436 EKE----------ERKHRKEKKKSVEERTEEE 457
KE E++H KE SV + +++
Sbjct: 563 GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 594
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 50.8 bits (120), Expect = 3e-06
Identities = 27/105 (25%), Positives = 65/105 (61%), Gaps = 7/105 (6%)
Query: 352 SENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKRE 411
S +++ D + ++K ++++R E+ +E+ E+E+ K + K+ + D+DK R++ RE
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREK-EREREKEREKEKERGKNKDRDKE-REKDRE 310
Query: 412 EDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+D+ K + R+++K H+ +KE+ K + ++K+ ++R++E
Sbjct: 311 KDKEKD-----REREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 331 NQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKER---PEKEQSK 387
N+++ S+ S + Q+ H+ + R R ++ + R P K++SK
Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 388 --HKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKE 445
+RK DK K R++ +E++RVK + K R+++K + E+ + K R +
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVK-EKDREKEREREKEREKEKERGKNKDRDK 303
Query: 446 KKKSVEERTEEE 457
+++ E+ +E+
Sbjct: 304 EREKDREKDKEK 315
Score = 47.4 bits (111), Expect = 3e-05
Identities = 24/99 (24%), Positives = 56/99 (56%), Gaps = 4/99 (4%)
Query: 359 HQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVS 418
H+ K + +++ R +++ + + K K K+ ++ D +K+ R+R++E ++ K
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE---REREKEREKEK-E 294
Query: 419 SGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
GK K R K++ D +KE+ + R+ +K+ ++R +E+
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Score = 45.8 bits (107), Expect = 8e-05
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 20/153 (13%)
Query: 329 SLNQQENNSGSYSVESEVYKHLSSENNTADHQAGH---KQKHQKRKRHLEEGKERPEKEQ 385
S ++ + S S S+ S N + Q K H+KR + E K R +
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR-SRSH 256
Query: 386 SKHKRKKSYE-----DTDLDKDKSIRQRKREEDRVKVSS-GKLKHRKKKKSHDVPSEKE- 438
S+ KRK + E + +KD+ ++R+RE++R K GK K R K++ D +KE
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDRE-KEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 439 ------ERKHRKE--KKKSVEERTEEEMLWDES 463
E++H K+ K+K E+ E+E D S
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDKEKEREKDRS 348
Score = 45.8 bits (107), Expect = 8e-05
Identities = 36/129 (27%), Positives = 67/129 (51%), Gaps = 6/129 (4%)
Query: 322 PEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERP 381
P K S ++++ S S+S + + + E + K + ++R+R E KE+
Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDK---RKDTREKIKEKERVKEKDREKEREREKEREKEK- 293
Query: 382 EKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVK-VSSGKLKHRKKKKSHDVPSEKEER 440
E+ ++K + K+ +D + DK+K R+R+RE++ K K K + K+K + KE
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKD-REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEID 352
Query: 441 KHRKEKKKS 449
+ RK+ KKS
Sbjct: 353 EKRKKDKKS 361
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/94 (31%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSI-RQRKREEDRVKV-SSGK 421
K+K ++++R E+ +E+ EKE+ K+K + + D +KDK R+R+RE++ K K
Sbjct: 275 KEKDREKEREREKEREK-EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 422 LKHRKKKKSHDVPSEKE-ERKHRKEKKKSVEERT 454
K + K+K + KE + K +K+KK R+
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 367
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 10/123 (8%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD 402
E + K E + K K + ++R + K++ EK++ + + K+ +D D +K+
Sbjct: 276 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-EKDREREREKEHEKDRDKEKE 334
Query: 403 KSI-RQRKREEDRVKVSSGKLKHRKKKK--------SHDVPSEKEERKHRKEKKKSVEER 453
K ++++RE+DR K K K KK + S S ER+ R+ + S R
Sbjct: 335 KEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPR 394
Query: 454 TEE 456
T +
Sbjct: 395 TSK 397
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/183 (23%), Positives = 72/183 (39%), Gaps = 29/183 (15%)
Query: 304 SKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGH 363
S+ R S + TR+ EK ++++ E E + + + + +
Sbjct: 251 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDRE 310
Query: 364 KQKHQKRKRHLEEGKER-----PEKEQSKHKRKKSYEDTDLD----KDK----------- 403
K K + R+R E+ E+ EKEQ K K ++ ++D KDK
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNA 370
Query: 404 ------SIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKS---VEERT 454
S R+R+R R S + K+KS PS + K K+++K + ER
Sbjct: 371 SRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR 430
Query: 455 EEE 457
E E
Sbjct: 431 ERE 433
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 327 PLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQS 386
P S E G + SS++++ ++ K + + R K+R +
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 387 KHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEK 446
KR KS E + R R D+ K + K+K +++ K D E+E K R+++
Sbjct: 239 HKKRSKSRER------RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKE 292
Query: 447 KKSVEERTEEE 457
K+ + + ++
Sbjct: 293 KERGKNKDRDK 303
Score = 37.0 bits (84), Expect = 0.038
Identities = 28/152 (18%), Positives = 59/152 (38%), Gaps = 12/152 (7%)
Query: 318 RDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKH--QKRKRHLE 375
+D EK ++ S ++ + K S + A + + ++R+R
Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS 386
Query: 376 EGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPS 435
R + KRK S + ++K ++R++E D + + + +KS +
Sbjct: 387 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 446
Query: 436 EKE----------ERKHRKEKKKSVEERTEEE 457
KE E++H KE SV + +++
Sbjct: 447 GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 478
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/110 (27%), Positives = 57/110 (51%), Gaps = 7/110 (6%)
Query: 353 ENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSI-----RQ 407
E + + +++ ++R+R E +ER E+E+ K + ++ D D D+ K R+
Sbjct: 306 EKERRERERERERERERRERERERERER-EREKEKERERERERDRDRDRTKERDRDRDRE 364
Query: 408 RKREEDRVKVSS-GKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
R R+ DR + S K + R ++KS D E+E + R+ +++ ER E
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERE 414
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/115 (22%), Positives = 59/115 (51%), Gaps = 10/115 (8%)
Query: 351 SSENNTADHQAGHKQKHQKRKRHLEEGKERP---EKEQSKHKRKKSYEDTDLDKDKSIRQ 407
SS+ N ++ K + ++R+R E +ER E+E+ + + ++ + + +KDK +
Sbjct: 374 SSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR 433
Query: 408 RKREEDRV-------KVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTE 455
+ EED K+ + ++++ K+ ++ K+ R++ KE ++ E R E
Sbjct: 434 EEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/135 (20%), Positives = 64/135 (47%), Gaps = 9/135 (6%)
Query: 330 LNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERP---EKEQS 386
L +++ E E + + + +++ ++R+R E+ KER E+++
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350
Query: 387 KHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSS-----GKLKHRKKKKSHDVPSEKEERK 441
+ + K+ D D ++D+ R R+R DR K S + + R++++ + E+E +
Sbjct: 351 RDRTKERDRDRDRERDRD-RDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 409
Query: 442 HRKEKKKSVEERTEE 456
R+ +++ ER E
Sbjct: 410 ERERERERERERERE 424
Score = 43.9 bits (102), Expect = 3e-04
Identities = 18/89 (20%), Positives = 53/89 (59%), Gaps = 3/89 (3%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREED---RVKVSSG 420
+++ ++R+R E +ER + + KR + ++ D + + + ++ RE++ + ++ +
Sbjct: 405 REREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNW 464
Query: 421 KLKHRKKKKSHDVPSEKEERKHRKEKKKS 449
+++ RKK + ++ +E+EE + R+ K++
Sbjct: 465 EIRERKKTREYEKEAEREEERRREMAKEA 493
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/115 (20%), Positives = 57/115 (49%), Gaps = 1/115 (0%)
Query: 342 VESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDK 401
+ E + E + D + K + + LEE K + EKE+ + ++++ + + ++
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERER 318
Query: 402 DKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
++ R+R+RE +R + K K R++++ D ++ + + R ++ +R E
Sbjct: 319 ERERRERERERERER-EREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRE 372
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 7/115 (6%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD 402
E E K E + + K + R R E ++R ++E+S + K + +D
Sbjct: 332 EREREKEKERERERERDRDRDRTKERDRDRDRERDRDR-DRERSSDRNKDRSRSREKSRD 390
Query: 403 KSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
+ R+R+RE +R + + R++++ + E+E + R++ KK E EE+
Sbjct: 391 RE-RERERERERERE-----REREREREREREREREREREREKDKKRDREEDEED 439
Score = 38.5 bits (88), Expect = 0.013
Identities = 32/140 (22%), Positives = 66/140 (47%), Gaps = 15/140 (10%)
Query: 321 FPEKP-VPLSLNQQENNSGSYSVESE---VYKHLSSENNTADHQAGHKQKHQKRKRHLEE 376
FP P +P L +E+ + E + + + +S +T H+ ++K +K K E
Sbjct: 248 FPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDT--HKKLEEEKGKKEKERQEI 305
Query: 377 GKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSE 436
KER E+E+ + + ++ E R+R+RE +R K + + R++ + D E
Sbjct: 306 EKERRERERERERERERRERE--------REREREREREK-EKERERERERDRDRDRTKE 356
Query: 437 KEERKHRKEKKKSVEERTEE 456
++ + R+ + ER+ +
Sbjct: 357 RDRDRDRERDRDRDRERSSD 376
Score = 37.7 bits (86), Expect = 0.022
Identities = 22/115 (19%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD 402
E E + E + + + + + R+R + +ER +++K + + + D +++
Sbjct: 336 EKEKERERERERDRDRDRTKERDRDRDRERDRDRDRER-SSDRNKDRSRSREKSRDRERE 394
Query: 403 KSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
+ R+R+RE +R + + + R++++ + EK++++ R+E ++ ER + E
Sbjct: 395 RE-RERERERERER-EREREREREREREREREREKDKKRDREEDEEDAYERRKLE 447
Score = 36.2 bits (82), Expect = 0.065
Identities = 20/92 (21%), Positives = 47/92 (51%), Gaps = 10/92 (10%)
Query: 366 KHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHR 425
+ ++++ +E + EKE+ + R++ + D D +++ ++E +R R
Sbjct: 523 RDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAER----------R 572
Query: 426 KKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
++ + P +EE + ++EK++ EE EEE
Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604
Score = 35.8 bits (81), Expect = 0.085
Identities = 18/91 (19%), Positives = 52/91 (57%), Gaps = 3/91 (3%)
Query: 364 KQKHQKRKRHLEEGKERPE-KEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKL 422
+ + + R+R + K+R +E+S+ + ++ + + ++++ R+R+RE +R + +
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERE-RERERERERER-ERERE 422
Query: 423 KHRKKKKSHDVPSEKEERKHRKEKKKSVEER 453
+ R+K K D ++E+ R++ ++ + E+
Sbjct: 423 REREKDKKRDREEDEEDAYERRKLERKLREK 453
Score = 34.3 bits (77), Expect = 0.25
Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 22/123 (17%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQK-------HQKRKRHLEEGKERPE---KEQSKH-KRK 391
E + Y+ E + +A ++++ +K+ R E+ ER E +E +K KR
Sbjct: 437 EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL 496
Query: 392 KSY-EDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSV 450
K + ED D D+D D L+ R + + ++ +++ +RK KE+ + +
Sbjct: 497 KEFLEDYDDDRD----------DPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI 546
Query: 451 EER 453
+R
Sbjct: 547 RQR 549
>gi|27883882 P18SRP protein [Homo sapiens]
Length = 155
Score = 50.1 bits (118), Expect = 4e-06
Identities = 33/109 (30%), Positives = 60/109 (55%), Gaps = 9/109 (8%)
Query: 351 SSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSK----HKRKKSYEDTDLDKDKSIR 406
SSE++ +++ +K + + KR EE +++ EK + K KRK+SY + ++D S +
Sbjct: 48 SSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTS-K 106
Query: 407 QRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTE 455
Q+K++ + + K KK K H +KE++K +KEK S +E
Sbjct: 107 QKKQKYQKKEKKKEKKSKSKKGKHH----KKEKKKRKKEKHSSTPNSSE 151
Score = 31.2 bits (69), Expect = 2.1
Identities = 19/68 (27%), Positives = 41/68 (60%), Gaps = 5/68 (7%)
Query: 395 EDTDLDKDKSIRQRK---REEDRVKVSSGKLKHRKKKKSHDVPSEKEE--RKHRKEKKKS 449
E+ +L+K +++++++ EE + + S K+K +KK+K S EE K +K+K +
Sbjct: 55 ENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQK 114
Query: 450 VEERTEEE 457
E++ E++
Sbjct: 115 KEKKKEKK 122
Score = 30.0 bits (66), Expect = 4.7
Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLE-EGKERPEKEQSKHKR 390
++E + ++ + + SS + D KQK+QK+++ E + K + K K K+
Sbjct: 77 KKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKK 136
Query: 391 KKSYEDTDLDKDKSIRQRK 409
K+ E + S RK
Sbjct: 137 KRKKEKHSSTPNSSEFSRK 155
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 50.1 bits (118), Expect = 4e-06
Identities = 27/103 (26%), Positives = 57/103 (55%), Gaps = 3/103 (2%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLK 423
+ + ++++R LE + R E+E+ + K + D D D D+ R+R+RE DR K + +
Sbjct: 697 RDREREKERELERERAR-EREREREKERDRERDRDRDHDRE-RERERERDREKERERERE 754
Query: 424 HRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILG 466
R++++ + E+E + R+ ++ +ER E + W++ G
Sbjct: 755 ERERERERERERERERERERERARERDKER-ERQRDWEDKDKG 796
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 18/140 (12%)
Query: 318 RDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEG 377
RD P P+ Q N E + + ++ D +A + + ++R R E
Sbjct: 637 RDQRPSSPI----RHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERE 692
Query: 378 KERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEK 437
+ER E+++ + K ++ + +++ R+R++E DR R + + HD E+
Sbjct: 693 RER-ERDREREKERELERERARERE---REREKERDR---------ERDRDRDHDRERER 739
Query: 438 E-ERKHRKEKKKSVEERTEE 456
E ER KE+++ EER E
Sbjct: 740 ERERDREKEREREREERERE 759
Score = 42.7 bits (99), Expect = 7e-04
Identities = 20/84 (23%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD--KSIRQRKREEDRVKVSSGK 421
+++ ++R+R E +ER + + +R++ +ED D +D + R+ RE+ + +
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDE 819
Query: 422 LKHRKKKKSHDVPSEKEERKHRKE 445
K +K+ ++ PS ++ K R+E
Sbjct: 820 RKSKKRYRNEGSPSPRQSPKRRRE 843
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/114 (18%), Positives = 62/114 (54%), Gaps = 4/114 (3%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKD 402
E E + E +A +++ ++++R E ++R + + +R++ E + +++
Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREK-ERERE 752
Query: 403 KSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
+ R+R+RE +R + + + R+++++ + E+E ++ ++K K ++R E+
Sbjct: 753 REERERERERERER---ERERERERERARERDKERERQRDWEDKDKGRDDRREK 803
Score = 41.6 bits (96), Expect = 0.002
Identities = 25/112 (22%), Positives = 61/112 (54%), Gaps = 4/112 (3%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERP-EKEQSKHK-RKKSYEDTDLD 400
E E + L E + K++ ++R R + +ER E+E+ + K R++ E+ + +
Sbjct: 700 EREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERE 759
Query: 401 KDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEE 452
+++ R+R+RE +R + + + +++++ D + + R R+EK++ + E
Sbjct: 760 RERE-RERERERERER-ERARERDKERERQRDWEDKDKGRDDRREKREEIRE 809
Score = 39.7 bits (91), Expect = 0.006
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 22/160 (13%)
Query: 317 TRDCFPEKP-VPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLE 375
TR +PE+ P N+ + S+ E + +N D + +HQ R LE
Sbjct: 598 TRSSYPERDRYPERDNRDQARDSSF--ERRHGERDRRDNRERDQRPSSPIRHQGRNDELE 655
Query: 376 EGKERPEKEQSKHKRKKSYEDTDLDKDKSI-----RQRKREEDRVKVSSGKL-------- 422
+ R E+ + ++ + D+++ R+R+RE DR + +L
Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARER 715
Query: 423 -----KHRKKKKSHDVPSEKE-ERKHRKEKKKSVEERTEE 456
K R +++ D ++E ER+ ++++K E EE
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERDREKEREREREE 755
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/138 (18%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Query: 318 RDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEG 377
RD EK L + E + + +++ + + + ++R+R EE
Sbjct: 697 RDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREER 756
Query: 378 KERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEK 437
+ E+E+ + + ++ + ++DK +R+R+ D G+ R+K++ ++ ++
Sbjct: 757 ERERERERERERERERERERARERDK---ERERQRDWEDKDKGRDDRREKRE--EIREDR 811
Query: 438 EERKHRKEKKKSVEERTE 455
R E+K R E
Sbjct: 812 NPRDGHDERKSKKRYRNE 829
Score = 33.5 bits (75), Expect = 0.42
Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 8/107 (7%)
Query: 359 HQAGHKQKHQKRKRHL----EEGKERPEKEQSKH-KRKKSYEDTDLDKDKSIRQRKREED 413
H Q+ Q RH E+G+ E+ H +R + EDT +D+ R+ E
Sbjct: 377 HSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREY 436
Query: 414 RVKVSSGKLKHRKKKKSHDVPSEKEER--KHRKEKKKSVEERTEEEM 458
SS + HR ++ D ++ R + R+E + S + R EM
Sbjct: 437 EQDQSSSR-DHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREM 482
Score = 33.5 bits (75), Expect = 0.42
Identities = 27/129 (20%), Positives = 49/129 (37%), Gaps = 17/129 (13%)
Query: 348 KHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQ 407
K + + D G + +KR+ E+ R ++ K K++ E + + R+
Sbjct: 782 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 841
Query: 408 RKREEDRVKVSSGKLKHRKKKKSHDVPSEKEER-----------------KHRKEKKKSV 450
R+ D +SG K+ K + V +E R + RK ++K
Sbjct: 842 REHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKES 901
Query: 451 EERTEEEML 459
R EE+ L
Sbjct: 902 SRRYEEQEL 910
Score = 32.7 bits (73), Expect = 0.72
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 21/149 (14%)
Query: 327 PLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQS 386
P+ + + + S S L S +N + H++G Q RKR L G EK +S
Sbjct: 1183 PMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQ--SGRKRVLHSGSRDREKTKS 1240
Query: 387 ------------KHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKK--SHD 432
+ KR + T D+ S R R S + H + S D
Sbjct: 1241 LEITGERKSRIDQLKRGEPSRSTSSDRQDS---RSHSSRRSSPESDRQVHSRSGSFDSRD 1297
Query: 433 VPSEKEERKHRKEKKKSVEERTEEEMLWD 461
E++ +H +E+++ E R + WD
Sbjct: 1298 RLQERDRYEHDRERER--ERRDTRQREWD 1324
Score = 32.3 bits (72), Expect = 0.94
Identities = 29/126 (23%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 339 SYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRK---KSYE 395
S V + + LS + T D Q K++ +K +R +E R E+++ K K K E
Sbjct: 865 SQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPER--KESSRRYEEQELKEKVSSVDKQRE 922
Query: 396 DTDLDKDKSIRQRK-----REEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSV 450
T++ + +R + + EDR +++KK K P +K++ ++ ++
Sbjct: 923 QTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNI 982
Query: 451 EERTEE 456
E +E+
Sbjct: 983 ETTSED 988
Score = 29.3 bits (64), Expect = 8.0
Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 47/137 (34%)
Query: 349 HLSSENNTADH-------QAGHKQKHQKRKRHLEEGKER--------------PEKEQSK 387
H S + T+D +A ++K K+K+ + G ER P+K Q K
Sbjct: 941 HQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKK 1000
Query: 388 H----KRKKSYEDTDLDKDKSIRQRKR-----------EEDRVKVSSGK---LKHRKKKK 429
KRKKS D+D+ +++ +Q K+ +E+ V++ +GK L+ +KK+
Sbjct: 1001 KSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKE 1060
Query: 430 --------SHDVPSEKE 438
DVP E
Sbjct: 1061 DTAFSDWSDEDVPDRTE 1077
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/412 (19%), Positives = 151/412 (36%), Gaps = 57/412 (13%)
Query: 72 RKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAMEKQLPHSKKTYD 131
R+ ++ ET R RE + RHR ++ + R + ++Q +
Sbjct: 66 REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNR-- 123
Query: 132 SFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRMCEQRFSHEASQ 191
Q E E + + RG D +T ++ RE D RE R R E+ E +
Sbjct: 124 --QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER 181
Query: 192 TYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKA-RGLEPKTCFRKIGDSS 250
R +R Q E E+ + + + RG E + + ++
Sbjct: 182 EKNR------------------QERRERERQREKENKTEDRHSERGRERE----RERETE 219
Query: 251 VETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLPAH------DS 304
ET R R+ R R R E++ + + + + E + +
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
Query: 305 KQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHK 364
+++ D + RD E+ ++ + E E + E + K
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 365 QKHQKRKRHLE-----------EGKERPEKE---------QSKHKRKKSYEDTDLDKDKS 404
++ +KRKR E EG+ + E+E QS +R++ D D D+ K
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKE 399
Query: 405 IRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
R+R+ E+DR + +++++ D SE+ + R+ +K+ ER E
Sbjct: 400 -RERQTEKDR---DGQRETEKQREREKDRESERGRERGREREKQKGRERDRE 447
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/134 (21%), Positives = 64/134 (47%), Gaps = 8/134 (5%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRK---RHLEEGKERP-EKEQSK 387
+Q + E K E N + + +Q+ ++ K RH E G+ER E+E
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 388 HKRKKSYEDTDLDKD-KSIRQRKREEDRVKVSSGKL---KHRKKKKSHDVPSEKEERKHR 443
+K D + D+ K+ R+R+++ +R + S + K R++++ D ++ +++
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 444 KEKKKSVEERTEEE 457
++ + + RTE +
Sbjct: 281 RQTDRKRQRRTERD 294
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 12/94 (12%)
Query: 364 KQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLK 423
K +H+KR RH E ++R EKE+ + TD ++D RQR++E +R K + +
Sbjct: 85 KDRHRKRDRHRERQRDR-EKERER--------QTDRERD---RQREKERNRQKERERETE 132
Query: 424 HRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
++ + ER+ +++ +K E +T+ E
Sbjct: 133 REGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/89 (24%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
Query: 374 LEEGKERPEKEQSKHKRK--KSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSH 431
L+ + RP ++S +R ++++D D D + RQ++RE R K + + RK+++
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRR 83
Query: 432 DVPSEKEERKHR---KEKKKSVEERTEEE 457
+ ++ +HR ++++K E +T+ E
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRE 112
Score = 38.1 bits (87), Expect = 0.017
Identities = 20/126 (15%), Positives = 58/126 (46%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRK 391
++ N E+E + T + +Q+ +++R + +ER + + +++
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 392 KSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVE 451
+ E ++ + RQR++E S + + R++++ + +E++ + R+ ++
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 452 ERTEEE 457
ER E+
Sbjct: 239 EREREK 244
Score = 35.8 bits (81), Expect = 0.085
Identities = 28/135 (20%), Positives = 58/135 (42%), Gaps = 23/135 (17%)
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQKRK--RHLEEGKERP-----EKEQSKHKRKKSYE 395
E E + E + + ++QK ++R+ R E G++R E+E+ + K+
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
Query: 396 DTDLDKDKSI---------RQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEK 446
TD ++ + R++ R+E R + R+++K + ER +E+
Sbjct: 162 QTDRERQRQTERNRQKEREREKNRQERRE-------RERQREKENKTEDRHSERGRERER 214
Query: 447 KKSVEERTEEEMLWD 461
++ E TE + D
Sbjct: 215 ERETETETERKRQTD 229
Score = 32.7 bits (73), Expect = 0.72
Identities = 74/376 (19%), Positives = 131/376 (34%), Gaps = 40/376 (10%)
Query: 43 RKTQDSYQNECADYINVQKARGLEAKTCFRKMEESSLETRRYREVVDSRPRHRMFEQRLP 102
R+ + + Q E + RG + +T ++ E + + RE R R R E+
Sbjct: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176
Query: 103 FETFRTYAAPYNISQAMEKQLPHSKKTYDSFQD-------ELEDYIKVQKARGLDPKTCF 155
E R + E+Q KT D + E E + ++ R D
Sbjct: 177 KEREREKNRQER--RERERQREKENKTEDRHSERGRERERERETETETERKRQTD----- 229
Query: 156 RKMRENSVDTHGYREMVDSGPRSRMCEQRFSHEASQTYQRPYHISPVESQLPQWLPTHSK 215
RE RE R R E+ + + +R Q + T K
Sbjct: 230 ---RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 216 RTYDSFQD-ELEDYIKVQKARGLEPKTCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLP 274
R + +D E E + Q+ R E + ++ + E R R+ R R + E+K
Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
Query: 275 CETFQTYSGPYSISQVVENQLPHCLPAHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQE 334
+T + Q A ++R + RD S ++E
Sbjct: 347 RQTEMDRERNRQTGREGRRQ------AERERER-------ERERD-------RQSARERE 386
Query: 335 NNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSY 394
+ + + +E + + KQ+ +++ R E G+ER +E+ K K ++
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER-GREREKQKGRERD 445
Query: 395 EDTDLDKDKSIRQRKR 410
+ D+ RQRKR
Sbjct: 446 RERQTDRQAG-RQRKR 460
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/119 (27%), Positives = 58/119 (48%), Gaps = 8/119 (6%)
Query: 341 SVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLD 400
++ESE + + +H+ H H K K+H ++ K K K R +S D+D D
Sbjct: 757 TLESERKRIFKDFMHVLEHECQHH--HSKNKKHSKKSK----KHHRKRSRSRSGSDSDDD 810
Query: 401 KDKSIRQRKREEDR--VKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
S ++R+R E R + SS R KKS + ++R+H+ + +S ER +++
Sbjct: 811 DSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDK 869
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/132 (21%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 332 QQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRK 391
+ + SGS S + + + + + + + H + + + + K + + ++ +HK
Sbjct: 798 RSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSD 857
Query: 392 KSYEDTDLDKDKSIRQRKREEDRVKV-SSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSV 450
D + +KDK + R+ E+DR + S K K KKK D + E +
Sbjct: 858 SPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEK 917
Query: 451 EERTEEEMLWDE 462
RT E L D+
Sbjct: 918 RRRTLLEQLDDD 929
Score = 37.7 bits (86), Expect = 0.022
Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 9/118 (7%)
Query: 349 HLSSENNTADHQAGHKQKHQKRKRHLEEGK---ERPEKEQSKHKRKKSYEDTDLDKDKSI 405
H + + + H K+KR E + E +S+ KKS + K +
Sbjct: 795 HRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRH 854
Query: 406 RQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDES 463
+ E D + K K R+ +K D ++ E KH+ KKK+ ++ WD S
Sbjct: 855 KSDSPESDAEREKDKKEKDRESEK--DRTRQRSESKHKSPKKKTGKDSGN----WDTS 906
Score = 37.0 bits (84), Expect = 0.038
Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 9/110 (8%)
Query: 351 SSENNTADHQAGHKQ--KHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQR 408
S +++A+ + +K+ KH+K+ + + PE + + K KK +D + +KD R R
Sbjct: 827 SEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKE-KDRESEKD---RTR 882
Query: 409 KREEDRVKVSSGKLKHRKKKKSHDVP-SEKEERKHRKEKKKSVEERTEEE 457
+R E + K S K K K + D SE E + K ++ +E+ +++
Sbjct: 883 QRSESKHK--SPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 48.5 bits (114), Expect = 1e-05
Identities = 32/133 (24%), Positives = 67/133 (50%), Gaps = 12/133 (9%)
Query: 326 VPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKE- 384
+P + + + G ++E + HL + + K+++H++E KE+PEK
Sbjct: 754 IPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIE----------KQEKHIKESKEKPEKRS 803
Query: 385 QSKHKRKKSYEDTDLDKDKSIR-QRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHR 443
Q K K + E +K+K I+ + K E+D++ +S K ++K K + +EK ++
Sbjct: 804 QIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGE 863
Query: 444 KEKKKSVEERTEE 456
K K + ++T++
Sbjct: 864 KSKNTAAIKKTDD 876
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/183 (22%), Positives = 77/183 (42%), Gaps = 31/183 (16%)
Query: 295 LPHCLPAHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSEN 354
L C+ K +L Y T C E ++ N+ + + K +
Sbjct: 837 LSECVDKIKEKDKL----YSHHTEKCHKE-------GEKSKNTAAIKKTDDREKSREKMD 885
Query: 355 NTADHQAGHKQKH--QKRKRHLEE--GKERPEKEQSKHKRKKSYE-DTDLDKDKSIRQRK 409
D + K++H + +++HL E K+ E SK ++ K+ E D +LDK + R ++
Sbjct: 886 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 945
Query: 410 ----------REEDRVKVSSG-KLKHRK----KKKSHDVPSEKEERKHRKEKKKSVEERT 454
+EE + + G K +H K K+K+ D P + + K + +K K ++
Sbjct: 946 SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYK 1005
Query: 455 EEE 457
E +
Sbjct: 1006 ERD 1008
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/140 (25%), Positives = 66/140 (47%), Gaps = 24/140 (17%)
Query: 340 YSVESE-VYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKE----QSKHKR---- 390
YS +E +K NTA + ++ + K + KE+PEKE +SK K
Sbjct: 851 YSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEK 910
Query: 391 ----------KKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKH-RKKKKSHDVPSEKEE 439
KS + + +KD+ + ++++ D+ ++ KH +++KKS V K +
Sbjct: 911 KNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQ 970
Query: 440 RKHRKEKKKSVEERTEEEML 459
EK S++E+T++E L
Sbjct: 971 H----EKPLSLKEKTKDEPL 986
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 37/154 (24%)
Query: 334 ENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKR--- 390
E+ S + +S++ K++ + +T K+KH ++R+ +E +++ +KE K R
Sbjct: 691 EHESLTLEKKSKLEKNIKDDKST-------KEKHVSKERNFKEERDKIKKESEKSFREEK 743
Query: 391 ----KKSYEDTDLDKDKSIRQR--------------------KREEDRVKVSSGKLKHRK 426
K+ E+ DKD +++E +K S K + R
Sbjct: 744 IKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRS 803
Query: 427 KKKSHDVPSEKEERK-HRKEKKKSVEERTEEEML 459
+ K D+ EK ERK KEKK E ++E++ L
Sbjct: 804 QIKEKDI--EKMERKTFEKEKKIKHEHKSEKDKL 835
Score = 38.9 bits (89), Expect = 0.010
Identities = 31/117 (26%), Positives = 60/117 (51%), Gaps = 8/117 (6%)
Query: 330 LNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHK 389
L+++E + S+ KH+ E ++ G+K +H+K E+ K+ P K +
Sbjct: 935 LDKKEKSRDKESINITNSKHIQEEKKSSIVD-GNKAQHEKPLSLKEKTKDEPLK--TPDG 991
Query: 390 RKKSYEDTDLDKDKSIRQRKREEDRVKVSS-GKLK-HRKKKKSHDVPSEKEERKHRK 444
++K +D D+D+ K +R + +D+++++S KLK K K P+ K+ R K
Sbjct: 992 KEKDKKDKDIDRYK---ERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEK 1045
Score = 35.8 bits (81), Expect = 0.085
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 27/154 (17%)
Query: 323 EKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEE------ 376
EK + S + E S ++ + + + + + + H+ K +K K L E
Sbjct: 789 EKHIKESKEKPEKRS---QIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIK 845
Query: 377 --------GKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVK------VSSGKL 422
E+ KE K K + + TD D++KS + R+ D+ K ++ K
Sbjct: 846 EKDKLYSHHTEKCHKEGEKSKNTAAIKKTD-DREKSREKMDRKHDKEKPEKERHLAESKE 904
Query: 423 KH---RKKKKSHDVPSEKEERKHRKEKKKSVEER 453
KH +K K+S + K E+ KEK + ++++
Sbjct: 905 KHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKK 938
Score = 34.3 bits (77), Expect = 0.25
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 17/108 (15%)
Query: 363 HKQKHQKRKR-HLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGK 421
HK+K + +K HLE G EK +K K + + T + D ++++ +E +K K
Sbjct: 579 HKEKSKHQKDFHLEFG----EKSNAKIK-DEDHSPTFENSDCTLKKMDKEGKTLK--KHK 631
Query: 422 LKHR---KKKKSHDVPSEKEERKHR---KEKKKSVEERTEEEMLWDES 463
LKH+ K+K ++ EKE+ K + KE ++SVE E W E+
Sbjct: 632 LKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDRE---FWKEN 676
Score = 32.7 bits (73), Expect = 0.72
Identities = 39/174 (22%), Positives = 66/174 (37%), Gaps = 20/174 (11%)
Query: 298 CLPAHDSKQRL--DSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENN 355
CL S+ L D + Y + PE S +E + E + +++
Sbjct: 543 CLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIK 602
Query: 356 TADHQAGHKQKHQKRKRHLEEGK-------ERPEKEQSKHKR-----KKSYEDTDLDKDK 403
DH + K+ +EGK + E+E+ KHK+ K+ Y+ D K+
Sbjct: 603 DEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKE- 661
Query: 404 SIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
QR E DR K K ++ D+ E EKK +E+ +++
Sbjct: 662 --LQRSVEFDR---EFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDD 710
Score = 32.7 bits (73), Expect = 0.72
Identities = 30/132 (22%), Positives = 59/132 (44%), Gaps = 23/132 (17%)
Query: 322 PEKPVPLSLNQQEN---NSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRK------- 371
PEK L+ +++++ S SE K +N D + K+K + ++
Sbjct: 893 PEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNS 952
Query: 372 RHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSH 431
+H++E K+ + +K + +K S++++ ++E +K GK K KK
Sbjct: 953 KHIQEEKKSSIVDGNKAQH---------EKPLSLKEKTKDEP-LKTPDGK---EKDKKDK 999
Query: 432 DVPSEKEERKHR 443
D+ KE KH+
Sbjct: 1000 DIDRYKERDKHK 1011
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 48.5 bits (114), Expect = 1e-05
Identities = 32/133 (24%), Positives = 67/133 (50%), Gaps = 12/133 (9%)
Query: 326 VPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKE- 384
+P + + + G ++E + HL + + K+++H++E KE+PEK
Sbjct: 777 IPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIE----------KQEKHIKESKEKPEKRS 826
Query: 385 QSKHKRKKSYEDTDLDKDKSIR-QRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHR 443
Q K K + E +K+K I+ + K E+D++ +S K ++K K + +EK ++
Sbjct: 827 QIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGE 886
Query: 444 KEKKKSVEERTEE 456
K K + ++T++
Sbjct: 887 KSKNTAAIKKTDD 899
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/183 (22%), Positives = 77/183 (42%), Gaps = 31/183 (16%)
Query: 295 LPHCLPAHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSEN 354
L C+ K +L Y T C E ++ N+ + + K +
Sbjct: 860 LSECVDKIKEKDKL----YSHHTEKCHKE-------GEKSKNTAAIKKTDDREKSREKMD 908
Query: 355 NTADHQAGHKQKH--QKRKRHLEE--GKERPEKEQSKHKRKKSYE-DTDLDKDKSIRQRK 409
D + K++H + +++HL E K+ E SK ++ K+ E D +LDK + R ++
Sbjct: 909 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 968
Query: 410 ----------REEDRVKVSSG-KLKHRK----KKKSHDVPSEKEERKHRKEKKKSVEERT 454
+EE + + G K +H K K+K+ D P + + K + +K K ++
Sbjct: 969 SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYK 1028
Query: 455 EEE 457
E +
Sbjct: 1029 ERD 1031
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/140 (25%), Positives = 66/140 (47%), Gaps = 24/140 (17%)
Query: 340 YSVESE-VYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKE----QSKHKR---- 390
YS +E +K NTA + ++ + K + KE+PEKE +SK K
Sbjct: 874 YSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEK 933
Query: 391 ----------KKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKH-RKKKKSHDVPSEKEE 439
KS + + +KD+ + ++++ D+ ++ KH +++KKS V K +
Sbjct: 934 KNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQ 993
Query: 440 RKHRKEKKKSVEERTEEEML 459
EK S++E+T++E L
Sbjct: 994 H----EKPLSLKEKTKDEPL 1009
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 37/154 (24%)
Query: 334 ENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKR--- 390
E+ S + +S++ K++ + +T K+KH ++R+ +E +++ +KE K R
Sbjct: 714 EHESLTLEKKSKLEKNIKDDKST-------KEKHVSKERNFKEERDKIKKESEKSFREEK 766
Query: 391 ----KKSYEDTDLDKDKSIRQR--------------------KREEDRVKVSSGKLKHRK 426
K+ E+ DKD +++E +K S K + R
Sbjct: 767 IKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRS 826
Query: 427 KKKSHDVPSEKEERK-HRKEKKKSVEERTEEEML 459
+ K D+ EK ERK KEKK E ++E++ L
Sbjct: 827 QIKEKDI--EKMERKTFEKEKKIKHEHKSEKDKL 858
Score = 38.9 bits (89), Expect = 0.010
Identities = 31/117 (26%), Positives = 60/117 (51%), Gaps = 8/117 (6%)
Query: 330 LNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHK 389
L+++E + S+ KH+ E ++ G+K +H+K E+ K+ P K +
Sbjct: 958 LDKKEKSRDKESINITNSKHIQEEKKSSIVD-GNKAQHEKPLSLKEKTKDEPLK--TPDG 1014
Query: 390 RKKSYEDTDLDKDKSIRQRKREEDRVKVSS-GKLK-HRKKKKSHDVPSEKEERKHRK 444
++K +D D+D+ K +R + +D+++++S KLK K K P+ K+ R K
Sbjct: 1015 KEKDKKDKDIDRYK---ERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEK 1068
Score = 35.8 bits (81), Expect = 0.085
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 27/154 (17%)
Query: 323 EKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEE------ 376
EK + S + E S ++ + + + + + + H+ K +K K L E
Sbjct: 812 EKHIKESKEKPEKRS---QIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIK 868
Query: 377 --------GKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVK------VSSGKL 422
E+ KE K K + + TD D++KS + R+ D+ K ++ K
Sbjct: 869 EKDKLYSHHTEKCHKEGEKSKNTAAIKKTD-DREKSREKMDRKHDKEKPEKERHLAESKE 927
Query: 423 KH---RKKKKSHDVPSEKEERKHRKEKKKSVEER 453
KH +K K+S + K E+ KEK + ++++
Sbjct: 928 KHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKK 961
Score = 34.3 bits (77), Expect = 0.25
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 17/108 (15%)
Query: 363 HKQKHQKRKR-HLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGK 421
HK+K + +K HLE G EK +K K + + T + D ++++ +E +K K
Sbjct: 602 HKEKSKHQKDFHLEFG----EKSNAKIK-DEDHSPTFENSDCTLKKMDKEGKTLK--KHK 654
Query: 422 LKHR---KKKKSHDVPSEKEERKHR---KEKKKSVEERTEEEMLWDES 463
LKH+ K+K ++ EKE+ K + KE ++SVE E W E+
Sbjct: 655 LKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDRE---FWKEN 699
Score = 32.7 bits (73), Expect = 0.72
Identities = 39/174 (22%), Positives = 66/174 (37%), Gaps = 20/174 (11%)
Query: 298 CLPAHDSKQRL--DSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENN 355
CL S+ L D + Y + PE S +E + E + +++
Sbjct: 566 CLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIK 625
Query: 356 TADHQAGHKQKHQKRKRHLEEGK-------ERPEKEQSKHKR-----KKSYEDTDLDKDK 403
DH + K+ +EGK + E+E+ KHK+ K+ Y+ D K+
Sbjct: 626 DEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKE- 684
Query: 404 SIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
QR E DR K K ++ D+ E EKK +E+ +++
Sbjct: 685 --LQRSVEFDR---EFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDD 733
Score = 32.7 bits (73), Expect = 0.72
Identities = 30/132 (22%), Positives = 59/132 (44%), Gaps = 23/132 (17%)
Query: 322 PEKPVPLSLNQQEN---NSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRK------- 371
PEK L+ +++++ S SE K +N D + K+K + ++
Sbjct: 916 PEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNS 975
Query: 372 RHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSH 431
+H++E K+ + +K + +K S++++ ++E +K GK K KK
Sbjct: 976 KHIQEEKKSSIVDGNKAQH---------EKPLSLKEKTKDEP-LKTPDGK---EKDKKDK 1022
Query: 432 DVPSEKEERKHR 443
D+ KE KH+
Sbjct: 1023 DIDRYKERDKHK 1034
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 47.8 bits (112), Expect = 2e-05
Identities = 33/157 (21%), Positives = 67/157 (42%), Gaps = 31/157 (19%)
Query: 329 SLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERP------- 381
S + GS S + E+ + E + +A ++K ++R R ++ G ER
Sbjct: 278 SRSHHREGHGSSSFDRELERE--KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRER 335
Query: 382 -----------------EKEQSKHKRKKSYEDTDLDKDKSI-----RQRKREEDRVKVSS 419
++E+ K + D D DK++ R+R RE + + S
Sbjct: 336 HRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR 395
Query: 420 GKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
G+++ +K K+ D +++++ K++KK R+ E
Sbjct: 396 GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRE 432
Score = 46.2 bits (108), Expect = 6e-05
Identities = 75/359 (20%), Positives = 134/359 (37%), Gaps = 64/359 (17%)
Query: 114 NISQAMEKQLPHSKKTYDSFQDELEDYIKVQKARG----LDPKTCFRKMRENSVDTHGY- 168
NI Q ++ + KK +E++ +++ +++R L P+ R+ R S G+
Sbjct: 228 NIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHG 287
Query: 169 -----REMVDSGPRSRMCEQRFSHEASQTYQRPYHISP-VESQLPQWLPTHSKRTYDSFQ 222
RE+ R R+ +R + E + +R I +E + + H R+ +
Sbjct: 288 SSSFDRELEREKERQRL--EREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRS--R 343
Query: 223 DELEDYIKVQKARGLEPKTCFRKIGDSSVETHRNREMVDVRPRHRMLEQKLPCETFQTYS 282
D D + R E + R+ D E RE R R R EQ+
Sbjct: 344 DRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR---------- 393
Query: 283 GPYSISQVVENQLPHCLPAHDSKQRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSV 342
S +V E + H D + R D RD EK
Sbjct: 394 ---SRGEVEEKK--HKEDKDDRRHRDDK-------RDSKKEK------------------ 423
Query: 343 ESEVYKHLSSENNTADHQAGHKQKHQ-KRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDK 401
KH S + H++ + ++ KR R + K K +SK K K +
Sbjct: 424 -----KHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGR 478
Query: 402 DKSIRQRKREEDRVKVSSGKLKHRKKKKSHD---VPSEKEERKHRKEKKKSVEERTEEE 457
S+ + K+ E + + R K++SH S+ + KH + + +S+E+ ++E+
Sbjct: 479 TDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEK 537
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/296 (21%), Positives = 115/296 (38%), Gaps = 53/296 (17%)
Query: 201 PVESQLPQWLPTHSKRTYDSFQD---ELEDYIKVQKARG----LEPKTCFRKIGDSSVET 253
PV+ + Q + T ++ ++ E++ +++ +++R L P+ R+ S
Sbjct: 224 PVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRR--SRSRSH 281
Query: 254 HR--------NREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLPAHDSK 305
HR +RE+ + R R+ + E + S SI + +E + H S+
Sbjct: 282 HREGHGSSSFDRELEREKERQRLEREAKEREKERRRSR--SIDRGLERRRSRSRERHRSR 339
Query: 306 QRLDSISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQ 365
R + RD EK EN G + + K +E ++ +
Sbjct: 340 SRSRDRKGDRRDRDREREK---------ENERGRRR-DRDYDKERGNEREKERERSRERS 389
Query: 366 KHQKRKRHLEEGKE-------------RPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREE 412
K Q+ + +EE K R K++ KH R +S E + +S KR
Sbjct: 390 KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449
Query: 413 DRVKVSSGKLKHRKKKKSH-----------DVPSEKEERKHRKEKKKSVEERTEEE 457
R K S K K+ K+KS+ D + ++R+H K+KS + +E
Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 47.4 bits (111), Expect = 3e-05
Identities = 28/140 (20%), Positives = 64/140 (45%), Gaps = 4/140 (2%)
Query: 318 RDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEG 377
RD EK +Q + E + E T H +++ ++++R +E
Sbjct: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
Query: 378 KERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEK 437
++R E+E+ K ++ D + D++ R+R+ E +R K + R +++ + E+
Sbjct: 120 RDR-EREKQKEMGRERQTDRETDRE---RERQAERERETGRERKTEDRHRERERERKRER 175
Query: 438 EERKHRKEKKKSVEERTEEE 457
E ++ KE+++ + E +
Sbjct: 176 ERKRETKERERHTDMERERQ 195
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/120 (17%), Positives = 59/120 (49%), Gaps = 11/120 (9%)
Query: 348 KHLSSENNTADHQAGHKQKHQKRKRHLEEGK---ERPEKEQSKHKRKKSYEDTDLDKDKS 404
+H +E T D Q +++ + + +E K E+++ + + + D D +++K
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
Query: 405 I-------RQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
R+R+R+ DR + + + + ++++ +++E +K ++ + + V +R E+
Sbjct: 68 TDREGERQRERERDRDRQR-ETERERDKERETDRHTETDRERQKQKEREMERVRDREREK 126
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/119 (20%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Query: 343 ESEVYKHLSSENNTAD-HQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDK 401
E++ + + E+ T D H +Q+ ++R R + +ER EK+ + ++ + D D+
Sbjct: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER-EKQTDREGERQRERERDRDR 84
Query: 402 DKSI---RQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
+ R ++RE DR + + + +K+++ V + E++ +++ + T+ E
Sbjct: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRE 143
Score = 32.3 bits (72), Expect = 0.94
Identities = 17/87 (19%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 376 EGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPS 435
EG+ + ++ ++++ +TD ++D++ ++ K E+ + + + R +++ D
Sbjct: 6 EGRHTHTETETMDRQRERRRETDRERDRA-KESKTEDRHSERDRQRDRERNRERDRDRER 64
Query: 436 EKE-----ERKHRKEKKKSVEERTEEE 457
EK+ ER+ +E+ + + TE E
Sbjct: 65 EKQTDREGERQRERERDRDRQRETERE 91
Score = 29.3 bits (64), Expect = 8.0
Identities = 18/74 (24%), Positives = 41/74 (55%), Gaps = 10/74 (13%)
Query: 385 QSKHKRKKSYEDTD-LDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHR 443
+SK + + ++ +T+ +D+ R+R+RE DR + K+ K+ D SE++ ++ R
Sbjct: 2 ESKTEGRHTHTETETMDRQ---RERRRETDRER------DRAKESKTEDRHSERDRQRDR 52
Query: 444 KEKKKSVEERTEEE 457
+ ++ +R E+
Sbjct: 53 ERNRERDRDREREK 66
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 47.4 bits (111), Expect = 3e-05
Identities = 40/152 (26%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 313 YCQLTRDCFPEKPVPLSL------NQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQK 366
+CQ + D K VP+++ N EN + E+ +LSS+ + + +
Sbjct: 1203 FCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD----EP 1258
Query: 367 HQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKR-EEDRVKVSSGKLKHR 425
+ +KR ++ +E P E++K+ + S D+D ++ K R R R ++ VS G+
Sbjct: 1259 EEGKKRTGKQNEENPGDEEAKN-QVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEE 1317
Query: 426 KKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
KK K P E +E K R +K S E+ + +
Sbjct: 1318 KKTK----PKEHKEVKGRNRRKVSSEDSEDSD 1345
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/159 (23%), Positives = 71/159 (44%), Gaps = 32/159 (20%)
Query: 331 NQQENNSGSYSVESEV--YKH--LSSENNTADHQAGHKQKHQKRKRHLEEGKER------ 380
NQ + S S S ES+ Y+H L + +D ++G ++K + ++ +G+ R
Sbjct: 1280 NQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSE 1339
Query: 381 ----------------PEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKH 424
E E + R +S + +L++++ ++K++ R+KV
Sbjct: 1340 DSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSE 1399
Query: 425 RKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDES 463
K SE+EE + +E+++ EE EEE D+S
Sbjct: 1400 NKSN------SEEEEEEKEEEEEEEEEEEEEEEDENDDS 1432
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/106 (19%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 358 DHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKV 417
++Q +KQK ++R+ ++E K S+ + ++ E+ + ++++ + +D
Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Query: 418 SSGKLKHRK-------KKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
G+ K RK + ++ + E+EER+ R +++ E+ E
Sbjct: 1436 GKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1481
Score = 34.7 bits (78), Expect = 0.19
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 31/150 (20%)
Query: 328 LSLNQQENNSGSYSVESEVYKHLSSEN-------------NTADHQAGHKQKHQKR---- 370
+S +++ S S + +SE+ K + S + NT D + +KH K+
Sbjct: 765 ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 824
Query: 371 --KRHLEEGKERPEKEQSKHKRKKSYEDTD--LDKDKSI----------RQRKREEDRVK 416
++L+ +E + + + ++++ + +DKD +I +Q D V
Sbjct: 825 QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 884
Query: 417 VSSGKLKHRKKKKSHDVPSEKEERKHRKEK 446
SGK + + V KE+ KH K K
Sbjct: 885 KLSGKEQSFTSLEVRKVAETKEKSKHLKTK 914
Score = 33.9 bits (76), Expect = 0.32
Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 324 KPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEK 383
K L NQ+ +V + SSEN + + +++ ++ + EE +E E
Sbjct: 1370 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN 1429
Query: 384 EQSKHKRKKSYEDTDLDKDKSIRQR-----KREEDRVKVSSGKLKHRKK 427
+ SK K + + KD +R K EE+R K + + + R+K
Sbjct: 1430 DDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREK 1478
Score = 33.9 bits (76), Expect = 0.32
Identities = 21/111 (18%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Query: 334 ENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKS 393
E N SY + + + E++++++++ +++ ++++ EE +E E+E+ ++ KS
Sbjct: 1375 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1434
Query: 394 YEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRK 444
K IR+ +++ + LK ++++ E+E K R+
Sbjct: 1435 ----PGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1481
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 47.4 bits (111), Expect = 3e-05
Identities = 40/152 (26%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 313 YCQLTRDCFPEKPVPLSL------NQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQK 366
+CQ + D K VP+++ N EN + E+ +LSS+ + + +
Sbjct: 1241 FCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD----EP 1296
Query: 367 HQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKR-EEDRVKVSSGKLKHR 425
+ +KR ++ +E P E++K+ + S D+D ++ K R R R ++ VS G+
Sbjct: 1297 EEGKKRTGKQNEENPGDEEAKN-QVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEE 1355
Query: 426 KKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
KK K P E +E K R +K S E+ + +
Sbjct: 1356 KKTK----PKEHKEVKGRNRRKVSSEDSEDSD 1383
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/159 (23%), Positives = 71/159 (44%), Gaps = 32/159 (20%)
Query: 331 NQQENNSGSYSVESEV--YKH--LSSENNTADHQAGHKQKHQKRKRHLEEGKER------ 380
NQ + S S S ES+ Y+H L + +D ++G ++K + ++ +G+ R
Sbjct: 1318 NQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSE 1377
Query: 381 ----------------PEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKH 424
E E + R +S + +L++++ ++K++ R+KV
Sbjct: 1378 DSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSE 1437
Query: 425 RKKKKSHDVPSEKEERKHRKEKKKSVEERTEEEMLWDES 463
K SE+EE + +E+++ EE EEE D+S
Sbjct: 1438 NKSN------SEEEEEEKEEEEEEEEEEEEEEEDENDDS 1470
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/106 (19%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 358 DHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKV 417
++Q +KQK ++R+ ++E K S+ + ++ E+ + ++++ + +D
Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1473
Query: 418 SSGKLKHRK-------KKKSHDVPSEKEERKHRKEKKKSVEERTEE 456
G+ K RK + ++ + E+EER+ R +++ E+ E
Sbjct: 1474 GKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1519
Score = 34.7 bits (78), Expect = 0.19
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 31/150 (20%)
Query: 328 LSLNQQENNSGSYSVESEVYKHLSSEN-------------NTADHQAGHKQKHQKR---- 370
+S +++ S S + +SE+ K + S + NT D + +KH K+
Sbjct: 803 ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 862
Query: 371 --KRHLEEGKERPEKEQSKHKRKKSYEDTD--LDKDKSI----------RQRKREEDRVK 416
++L+ +E + + + ++++ + +DKD +I +Q D V
Sbjct: 863 QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVD 922
Query: 417 VSSGKLKHRKKKKSHDVPSEKEERKHRKEK 446
SGK + + V KE+ KH K K
Sbjct: 923 KLSGKEQSFTSLEVRKVAETKEKSKHLKTK 952
Score = 33.9 bits (76), Expect = 0.32
Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 324 KPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEK 383
K L NQ+ +V + SSEN + + +++ ++ + EE +E E
Sbjct: 1408 KKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN 1467
Query: 384 EQSKHKRKKSYEDTDLDKDKSIRQR-----KREEDRVKVSSGKLKHRKK 427
+ SK K + + KD +R K EE+R K + + + R+K
Sbjct: 1468 DDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREK 1516
Score = 33.9 bits (76), Expect = 0.32
Identities = 21/111 (18%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Query: 334 ENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKS 393
E N SY + + + E++++++++ +++ ++++ EE +E E+E+ ++ KS
Sbjct: 1413 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1472
Query: 394 YEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRK 444
K IR+ +++ + LK ++++ E+E K R+
Sbjct: 1473 ----PGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1519
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 47.4 bits (111), Expect = 3e-05
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 338 GSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDT 397
G SV E S D +G K +K K L + E E+ K + E
Sbjct: 1297 GEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1355
Query: 398 DLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEE 452
D KS +++K+ + R K K K +K KK+ SE +K +K+KKK+ E+
Sbjct: 1356 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1410
Score = 31.6 bits (70), Expect = 1.6
Identities = 19/98 (19%), Positives = 40/98 (40%)
Query: 360 QAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSS 419
+ G ++ +GK + +K K KK K + + ++ V
Sbjct: 1295 EGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEG 1354
Query: 420 GKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
G + K KK ++++ K +KEKKK ++ + ++
Sbjct: 1355 GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKD 1392
Score = 30.4 bits (67), Expect = 3.6
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 20/121 (16%)
Query: 356 TADHQAGHKQKHQKRKR-HLEEGKER---PEK----EQSKHKRKKSYEDTDLDKDKSI-- 405
+ D A + +K+K+ EG E PEK + K KR K+ D K K
Sbjct: 1274 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1333
Query: 406 RQRKREEDRVKVSSG----------KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTE 455
Q ++E ++ G K +K+KK D + +E+K +K+K K +
Sbjct: 1334 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1393
Query: 456 E 456
E
Sbjct: 1394 E 1394
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 47.4 bits (111), Expect = 3e-05
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 338 GSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDT 397
G SV E S D +G K +K K L + E E+ K + E
Sbjct: 1336 GEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1394
Query: 398 DLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEE 452
D KS +++K+ + R K K K +K KK+ SE +K +K+KKK+ E+
Sbjct: 1395 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
Score = 31.6 bits (70), Expect = 1.6
Identities = 19/98 (19%), Positives = 40/98 (40%)
Query: 360 QAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSS 419
+ G ++ +GK + +K K KK K + + ++ V
Sbjct: 1334 EGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEG 1393
Query: 420 GKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
G + K KK ++++ K +KEKKK ++ + ++
Sbjct: 1394 GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKD 1431
Score = 30.4 bits (67), Expect = 3.6
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 20/121 (16%)
Query: 356 TADHQAGHKQKHQKRKR-HLEEGKER---PEK----EQSKHKRKKSYEDTDLDKDKSI-- 405
+ D A + +K+K+ EG E PEK + K KR K+ D K K
Sbjct: 1313 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1372
Query: 406 RQRKREEDRVKVSSG----------KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTE 455
Q ++E ++ G K +K+KK D + +E+K +K+K K +
Sbjct: 1373 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1432
Query: 456 E 456
E
Sbjct: 1433 E 1433
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 47.4 bits (111), Expect = 3e-05
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 338 GSYSVESEVYKHLSSENNTADHQAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDT 397
G SV E S D +G K +K K L + E E+ K + E
Sbjct: 1373 GEASVSPEKTSTTSKGKAKRDKASGDV-KEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1431
Query: 398 DLDKDKSIRQRKREEDRVKVSSGKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEE 452
D KS +++K+ + R K K K +K KK+ SE +K +K+KKK+ E+
Sbjct: 1432 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1486
Score = 31.6 bits (70), Expect = 1.6
Identities = 19/98 (19%), Positives = 40/98 (40%)
Query: 360 QAGHKQKHQKRKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSS 419
+ G ++ +GK + +K K KK K + + ++ V
Sbjct: 1371 EGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEG 1430
Query: 420 GKLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTEEE 457
G + K KK ++++ K +KEKKK ++ + ++
Sbjct: 1431 GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKD 1468
Score = 30.4 bits (67), Expect = 3.6
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 20/121 (16%)
Query: 356 TADHQAGHKQKHQKRKR-HLEEGKER---PEK----EQSKHKRKKSYEDTDLDKDKSI-- 405
+ D A + +K+K+ EG E PEK + K KR K+ D K K
Sbjct: 1350 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1409
Query: 406 RQRKREEDRVKVSSG----------KLKHRKKKKSHDVPSEKEERKHRKEKKKSVEERTE 455
Q ++E ++ G K +K+KK D + +E+K +K+K K +
Sbjct: 1410 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1469
Query: 456 E 456
E
Sbjct: 1470 E 1470
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,733,780
Number of Sequences: 37866
Number of extensions: 911475
Number of successful extensions: 16297
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 420
Number of HSP's successfully gapped in prelim test: 558
Number of HSP's that attempted gapping in prelim test: 6561
Number of HSP's gapped (non-prelim): 5577
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.