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Search of human proteins with 58533165
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
sapiens]
(285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s... 627 e-180
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s... 623 e-179
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s... 621 e-178
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho... 617 e-177
gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo s... 427 e-120
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 238 3e-63
gi|4505881 plasminogen [Homo sapiens] 223 1e-58
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 177 1e-44
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 115 4e-26
gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 106 2e-23
gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 106 2e-23
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 104 1e-22
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 104 1e-22
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec... 94 1e-19
gi|134152686 receptor tyrosine kinase-like orphan receptor 1 iso... 85 6e-17
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso... 85 8e-17
gi|24041012 kringle-containing transmembrane protein 1 isoform 2... 68 1e-11
gi|227116325 kringle-containing transmembrane protein 1 isoform ... 68 1e-11
gi|145275213 coagulation factor XII precursor [Homo sapiens] 64 2e-10
gi|13375642 kringle-containing transmembrane protein 2 isoform b... 61 1e-09
gi|27437008 kringle-containing transmembrane protein 2 isoform d... 61 1e-09
gi|4504383 HGF activator preproprotein [Homo sapiens] 59 6e-09
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi... 57 2e-08
gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo ... 50 2e-06
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 46 3e-05
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 46 3e-05
gi|4506143 neurotrypsin precursor [Homo sapiens] 46 3e-05
gi|209571507 HGFL protein isoform 2 [Homo sapiens] 37 0.020
gi|51317358 HGFL protein isoform 1 [Homo sapiens] 37 0.020
gi|40806187 ADAM metallopeptidase with thrombospondin type 1 mot... 35 0.058
>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
sapiens]
Length = 285
Score = 627 bits (1617), Expect = e-180
Identities = 285/285 (100%), Positives = 285/285 (100%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
Query: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF
Sbjct: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
Query: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET
Sbjct: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
Length = 723
Score = 623 bits (1607), Expect = e-179
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQENYCRNPRGEEG 180
Query: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF
Sbjct: 181 GPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKF 240
Query: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC
Sbjct: 241 LPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
Score = 152 bits (383), Expect = 4e-37
Identities = 72/175 (41%), Positives = 93/175 (53%), Gaps = 19/175 (10%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNPRGEEGGP 182
C+ G SY+G + T+SG CQ W PH H Y K +NYCRNP G+ P
Sbjct: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR-P 264
Query: 183 WCFTSNPEVRYEVCDIPQCSE------------VECMTCNGESYRGLMDHTESGKICQRW 230
WC+T +P R+E C I C++ EC+ GE YRG ++ +G CQRW
Sbjct: 265 WCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRW 324
Query: 231 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCA-IKTCE 284
D Q PH H PE + K +NYCRNPDG PWC+T DP+ R YC+ I C+
Sbjct: 325 DSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD 379
Score = 150 bits (378), Expect = 2e-36
Identities = 77/170 (45%), Positives = 96/170 (56%), Gaps = 17/170 (10%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEEGGP 182
CI G+G Y+GTV+ +GI CQ W S PHEH +++ KDL+ENYCRNP G E P
Sbjct: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSES-P 358
Query: 183 WCFTSNPEVRYEVCD-IPQCSEV---ECMTCNGESYRGLMDHTESGKICQRWDHQTP--H 236
WCFT++P +R C IP C +C NG++Y G + T SG C WD H
Sbjct: 359 WCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH 418
Query: 237 RHKFLPERYPDKG-FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCE 284
RH F PD ++NYCRNPD PWCYT +P W+YC I CE
Sbjct: 419 RHIFWE---PDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCE 465
Score = 74.3 bits (181), Expect = 1e-13
Identities = 32/81 (39%), Positives = 47/81 (58%), Gaps = 5/81 (6%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP--HEHSYRGKD---LQENYCRNPRGEEG 180
++C G G++Y G +S T+SG+ C W + H H + D L ENYCRNP +
Sbjct: 384 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 443
Query: 181 GPWCFTSNPEVRYEVCDIPQC 201
GPWC+T NP + ++ C I +C
Sbjct: 444 GPWCYTGNPLIPWDYCPISRC 464
>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
sapiens]
Length = 290
Score = 621 bits (1601), Expect = e-178
Identities = 285/290 (98%), Positives = 285/290 (98%), Gaps = 5/290 (1%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 235
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
Query: 236 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET
Sbjct: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
sapiens]
Length = 728
Score = 617 bits (1591), Expect = e-177
Identities = 283/288 (98%), Positives = 283/288 (98%), Gaps = 5/288 (1%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 235
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
Query: 236 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC
Sbjct: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
Score = 152 bits (383), Expect = 4e-37
Identities = 72/175 (41%), Positives = 93/175 (53%), Gaps = 19/175 (10%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNPRGEEGGP 182
C+ G SY+G + T+SG CQ W PH H Y K +NYCRNP G+ P
Sbjct: 211 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR-P 269
Query: 183 WCFTSNPEVRYEVCDIPQCSE------------VECMTCNGESYRGLMDHTESGKICQRW 230
WC+T +P R+E C I C++ EC+ GE YRG ++ +G CQRW
Sbjct: 270 WCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRW 329
Query: 231 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCA-IKTCE 284
D Q PH H PE + K +NYCRNPDG PWC+T DP+ R YC+ I C+
Sbjct: 330 DSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD 384
Score = 150 bits (378), Expect = 2e-36
Identities = 77/170 (45%), Positives = 96/170 (56%), Gaps = 17/170 (10%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEEGGP 182
CI G+G Y+GTV+ +GI CQ W S PHEH +++ KDL+ENYCRNP G E P
Sbjct: 305 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSES-P 363
Query: 183 WCFTSNPEVRYEVCD-IPQCSEV---ECMTCNGESYRGLMDHTESGKICQRWDHQTP--H 236
WCFT++P +R C IP C +C NG++Y G + T SG C WD H
Sbjct: 364 WCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH 423
Query: 237 RHKFLPERYPDKG-FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCE 284
RH F PD ++NYCRNPD PWCYT +P W+YC I CE
Sbjct: 424 RHIFWE---PDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCE 470
Score = 74.3 bits (181), Expect = 1e-13
Identities = 32/81 (39%), Positives = 47/81 (58%), Gaps = 5/81 (6%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIP--HEHSYRGKD---LQENYCRNPRGEEG 180
++C G G++Y G +S T+SG+ C W + H H + D L ENYCRNP +
Sbjct: 389 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 448
Query: 181 GPWCFTSNPEVRYEVCDIPQC 201
GPWC+T NP + ++ C I +C
Sbjct: 449 GPWCYTGNPLIPWDYCPISRC 469
>gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo
sapiens]
Length = 210
Score = 427 bits (1098), Expect = e-120
Identities = 203/208 (97%), Positives = 203/208 (97%), Gaps = 5/208 (2%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 203
RGEEGGPWCFTSNPEVRYEVCDIPQCSE
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
Score = 85.1 bits (209), Expect = 6e-17
Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP-RP 264
C+ G SY+G + T+SG CQ W PH H FLP Y K +NYCRNP G+ P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 265 WCYTLDPHTRWEYCAIKTC 283
WC+T +P R+E C I C
Sbjct: 188 WCFTSNPEVRYEVCDIPQC 206
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 238 bits (608), Expect = 3e-63
Identities = 117/287 (40%), Positives = 163/287 (56%), Gaps = 14/287 (4%)
Query: 2 WVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIKT 61
WVT PA + + L LLL G +R+ +++F+ T L + A+
Sbjct: 5 WVTVQPPARRMGWLPLLLLLTQCL-----GVPGQRSPLNDFQVLRGTELQHLLHAVVPGP 59
Query: 62 KKVNTAD--QCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLY 119
+ + AD +CA RC G C+AF ++ + C P+ S + DL+
Sbjct: 60 WQEDVADAEECAGRC----GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLF 115
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRG---KDLQENYCRNPR 176
+ KDY+R CI+ G Y+GT++ T G+ CQ WS P++H Y L+EN+CRNP
Sbjct: 116 QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNGLEENFCRNPD 175
Query: 177 GEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPH 236
G+ GGPWC+T++P VR++ C I C E C+ CNGE YRG +D TESG+ CQRWD Q PH
Sbjct: 176 GDPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPH 235
Query: 237 RHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
+H F P ++ D+G DDNYCRNPDG RPWCYT DP E+C + C
Sbjct: 236 QHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRC 282
Score = 161 bits (408), Expect = 5e-40
Identities = 74/168 (44%), Positives = 100/168 (59%), Gaps = 12/168 (7%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEEGG 181
+C GKG Y+GT + T +G+ CQ W + IPH+H Y KDL+EN+CRNP G E
Sbjct: 296 SCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEA- 354
Query: 182 PWCFTSNPEVRYEVC-DIPQCSE----VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 236
PWCFT P +R C I +C++ +C GE YRG + T G CQRW +TPH
Sbjct: 355 PWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPH 414
Query: 237 RHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTC 283
+ +F P ++N+CRNPDG PWCYT+DP T ++YCA++ C
Sbjct: 415 KPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRC 462
Score = 161 bits (407), Expect = 7e-40
Identities = 73/172 (42%), Positives = 98/172 (56%), Gaps = 17/172 (9%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR-----GKDLQENYCRNPRGEEGGP 182
C+ G Y+G V T+SG +CQ W PH+H + + L +NYCRNP G E P
Sbjct: 205 CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSER-P 263
Query: 183 WCFTSNPEVRYEVCDIPQCSE----------VECMTCNGESYRGLMDHTESGKICQRWDH 232
WC+T++P++ E CD+P+C V C GE YRG + T +G CQRWD
Sbjct: 264 WCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDA 323
Query: 233 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYC-AIKTC 283
Q PH+H+F PE+Y K +N+CRNPDG PWC+TL P R +C I+ C
Sbjct: 324 QIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRRC 375
Score = 82.8 bits (203), Expect = 3e-16
Identities = 32/83 (38%), Positives = 52/83 (62%), Gaps = 5/83 (6%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR-----GKDLQENYCRNPRGEEG 180
++C G G Y+GTVS T+ G++CQ WS+ PH+ + L+EN+CRNP G+
Sbjct: 382 QDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSH 441
Query: 181 GPWCFTSNPEVRYEVCDIPQCSE 203
GPWC+T +P ++ C + +C++
Sbjct: 442 GPWCYTMDPRTPFDYCALRRCAD 464
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 223 bits (568), Expect = 1e-58
Identities = 103/233 (44%), Positives = 144/233 (61%), Gaps = 13/233 (5%)
Query: 61 TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
TKK + ++CA +C ++ FTC+AF + +QC+ N SS + + +
Sbjct: 37 TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92
Query: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR-----GKDLQENYC 172
L+E K Y+ C G G++Y+GT+S TK+GI CQ WSS PH + + L+ENYC
Sbjct: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
Query: 173 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDH 232
RNP + GPWC+T++PE RY+ CDI +C E ECM C+GE+Y G + T SG CQ WD
Sbjct: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE-ECMHCSGENYDGKISKTMSGLECQAWDS 211
Query: 233 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
Q+PH H ++P ++P+K NYCRNPD + RPWC+T DP+ RWE C I C T
Sbjct: 212 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTT 264
Score = 179 bits (453), Expect = 3e-45
Identities = 79/171 (46%), Positives = 105/171 (61%), Gaps = 14/171 (8%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSY-----RGKDLQENYCRNPRGEEGGP 182
C+ G +Y G +S T SG++CQ W S PH H Y K+L++NYCRNP E P
Sbjct: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243
Query: 183 WCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTESGKICQRWDHQT 234
WCFT++P R+E+CDIP+C+ +C+ GE+YRG + T SG CQ W QT
Sbjct: 244 WCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQT 303
Query: 235 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
PH H PE +P K D+NYCRNPDG+ PWC+T + RWEYC I +C++
Sbjct: 304 PHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDS 354
Score = 176 bits (446), Expect = 2e-44
Identities = 80/181 (44%), Positives = 101/181 (55%), Gaps = 26/181 (14%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNPRGEEGGP 182
C+ G G +Y+G V++T SG CQ WS+ PH H+ + K+L ENYCRNP G+ P
Sbjct: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRA-P 333
Query: 183 WCFTSNPEVRYEVCDIPQCSEV--------------------ECMTCNGESYRGLMDHTE 222
WC T+N +VR+E C IP C +C +G+SYRG T
Sbjct: 334 WCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT 393
Query: 223 SGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKT 282
+GK CQ W TPHRH+ PE YP+ G NYCRNPD PWC+T DP RWEYC +K
Sbjct: 394 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453
Query: 283 C 283
C
Sbjct: 454 C 454
Score = 163 bits (412), Expect = 2e-40
Identities = 81/188 (43%), Positives = 104/188 (55%), Gaps = 30/188 (15%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEE 179
+++C G G+SY+GT S T +G KCQ WSSM PH H +Y L NYCRNP ++
Sbjct: 374 VQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK 433
Query: 180 GGPWCFTSNPEVRYEVCDIPQC----------------------SEVECMTCNGESYRGL 217
GPWCFT++P VR+E C++ +C SE +CM NG+ YRG
Sbjct: 434 -GPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGK 492
Query: 218 MDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQ-PRPWCYTLDPHTRW 275
T +G CQ W Q PHRH F PE P G + NYCRNPDG PWCYT +P +
Sbjct: 493 RATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLY 552
Query: 276 EYCAIKTC 283
+YC + C
Sbjct: 553 DYCDVPQC 560
Score = 97.1 bits (240), Expect = 2e-20
Identities = 47/129 (36%), Positives = 67/129 (51%), Gaps = 21/129 (16%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKD------LQENYCRNPRGEEG 180
+C+ G G+ Y+G + T +G CQ W++ PH HS + L++NYCRNP G+ G
Sbjct: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539
Query: 181 GPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRWD 231
GPWC+T+NP Y+ CD+PQC+ +VE C G G + H S W
Sbjct: 540 GPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHS------WP 593
Query: 232 HQTPHRHKF 240
Q R +F
Sbjct: 594 WQVSLRTRF 602
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 177 bits (448), Expect = 1e-44
Identities = 85/201 (42%), Positives = 106/201 (52%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRN 174
E +++C G GRSY+G S T +G CQ WSSMIPH H +Y L ENYCRN
Sbjct: 1494 EKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRN 1553
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P + PWC+T++P VR+E C++ QCSE E
Sbjct: 1554 PDSGK-QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPV 1612
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPHRH+ PE YP+ G NYCRNPD
Sbjct: 1613 VRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADT 1672
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
PWC+T+DP RWEYC + C
Sbjct: 1673 GPWCFTMDPSIRWEYCNLTRC 1693
Score = 174 bits (441), Expect = 8e-44
Identities = 82/201 (40%), Positives = 105/201 (52%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT IT +G CQ WSSM PH HS Y L +NYCRN
Sbjct: 932 EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P PWC+T++P VR+E C++ +CS+ E
Sbjct: 992 P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C G+SYRG T +G+ CQ W TPH+H PE YP+ G NYCRNPD +
Sbjct: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
RPWCYT+DP RWEYC + C
Sbjct: 1111 RPWCYTMDPSVRWEYCNLTQC 1131
Score = 167 bits (424), Expect = 7e-42
Identities = 80/193 (41%), Positives = 101/193 (52%), Gaps = 30/193 (15%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E +++C G G+SY+G+ S T +G CQ WSSM PH H Y L NYCRN
Sbjct: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE------------------------CMTCN 210
P E PWC+T +P VR+E C++ QC E C +
Sbjct: 1220 PDAEIS-PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
Query: 211 GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLD 270
G+SYRG T +G+ CQ W TPH H+ E YP+ G NYCRNPD + RPWCYT+D
Sbjct: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
Query: 271 PHTRWEYCAIKTC 283
P RWEYC + C
Sbjct: 1339 PSVRWEYCNLTQC 1351
Score = 167 bits (424), Expect = 7e-42
Identities = 80/201 (39%), Positives = 104/201 (51%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E +++C G G+SY+G+ S T +G CQ WSSM PH H Y L NYCRN
Sbjct: 1266 EQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1325
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P E PWC+T +P VR+E C++ QC +E
Sbjct: 1326 PDAEIR-PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTG 1384
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C +G+SYRG + T +G+ CQ W TPH H+ +P YP+ G NYCRNPD +
Sbjct: 1385 VQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEI 1444
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
RPWCYT+DP RWEYC + C
Sbjct: 1445 RPWCYTMDPSVRWEYCNLTRC 1465
Score = 166 bits (420), Expect = 2e-41
Identities = 80/201 (39%), Positives = 102/201 (50%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
EN +++C G G+SY+GT+S T +G CQ WSSM PH H Y L NYCRN
Sbjct: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P E PWC+T +P VR+E C++ +C E
Sbjct: 1440 PDAEIR-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPV 1498
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C +G SYRG+ T +G+ CQ W PH H+ PE YP+ G +NYCRNPD
Sbjct: 1499 VQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGK 1558
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
+PWCYT DP RWEYC + C
Sbjct: 1559 QPWCYTTDPCVRWEYCNLTQC 1579
Score = 165 bits (417), Expect = 5e-41
Identities = 81/203 (39%), Positives = 103/203 (50%), Gaps = 38/203 (18%)
Query: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYC 172
L E +++C G+SY+GT S T +G CQ WSSM PH+HS Y L NYC
Sbjct: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
Query: 173 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE--------------------------- 205
RNP E PWC+T +P VR+E C++ QC E
Sbjct: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
Query: 206 -----CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C +G+SYRG T +G+ CQ W TPH H+ E YP+ G NYCRNPD
Sbjct: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
Query: 261 QPRPWCYTLDPHTRWEYCAIKTC 283
+ PWCYT+DP+ RWEYC + C
Sbjct: 1223 EISPWCYTMDPNVRWEYCNLTQC 1245
Score = 162 bits (410), Expect = 3e-40
Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 194 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
P+CYT DP RWEYC + C
Sbjct: 313 APYCYTRDPGVRWEYCNLTQC 333
Score = 162 bits (410), Expect = 3e-40
Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 308 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
P+CYT DP RWEYC + C
Sbjct: 427 APYCYTRDPGVRWEYCNLTQC 447
Score = 162 bits (410), Expect = 3e-40
Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 422 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
P+CYT DP RWEYC + C
Sbjct: 541 APYCYTRDPGVRWEYCNLTQC 561
Score = 162 bits (410), Expect = 3e-40
Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 476 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 536 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 595 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 654
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
P+CYT DP RWEYC + C
Sbjct: 655 APYCYTRDPGVRWEYCNLTQC 675
Score = 162 bits (410), Expect = 3e-40
Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 590 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 650 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 709 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
P+CYT DP RWEYC + C
Sbjct: 769 APYCYTRDPGVRWEYCNLTQC 789
Score = 162 bits (409), Expect = 4e-40
Identities = 80/201 (39%), Positives = 101/201 (50%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E +++C G G+SY+GT S T +G CQ WSSM PH+H+ Y L NYCRN
Sbjct: 20 EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 80 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
P+CYT DP RWEYC + C
Sbjct: 199 APYCYTRDPGVRWEYCNLTQC 219
Score = 162 bits (409), Expect = 4e-40
Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 704 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 764 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
Query: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 823 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
P+CYT DP RWEYC + C
Sbjct: 883 APYCYTRDPSVRWEYCNLTQC 903
Score = 162 bits (409), Expect = 4e-40
Identities = 80/201 (39%), Positives = 99/201 (49%), Gaps = 38/201 (18%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS Y L NYCRN
Sbjct: 818 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 877
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEV------------------------------ 204
P P+C+T +P VR+E C++ QCS+
Sbjct: 878 P-DPVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPG 936
Query: 205 --ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262
EC NG+SY+G T +G+ CQ W TPH H P YP+ G NYCRNPD
Sbjct: 937 VQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVA 996
Query: 263 RPWCYTLDPHTRWEYCAIKTC 283
PWCYT DP RWEYC + C
Sbjct: 997 APWCYTTDPSVRWEYCNLTRC 1017
Score = 159 bits (401), Expect = 3e-39
Identities = 80/193 (41%), Positives = 101/193 (52%), Gaps = 30/193 (15%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRN 174
E +R C G G+SY+GT S T +G CQ WSSM PH H +Y L NYCRN
Sbjct: 1608 EQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRN 1667
Query: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------CMTCNGE 212
P + GPWCFT +P +R+E C++ +CS+ E CM NG+
Sbjct: 1668 PDADT-GPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGK 1726
Query: 213 SYRGLMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQPR-PWCYTLD 270
YRG T +G CQ W Q PHRH F+P G + NYCRNPDG PWCYT++
Sbjct: 1727 GYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMN 1786
Query: 271 PHTRWEYCAIKTC 283
P ++YC I C
Sbjct: 1787 PRKLFDYCDIPLC 1799
Score = 95.1 bits (235), Expect = 6e-20
Identities = 41/87 (47%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Query: 199 PQCSEV--ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCR 256
P+ S V +C +G+SYRG T +G+ CQ W TPH+H E YP+ G NYCR
Sbjct: 19 PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
Query: 257 NPDGQPRPWCYTLDPHTRWEYCAIKTC 283
NPD P+CYT DP RWEYC + C
Sbjct: 79 NPDAVAAPYCYTRDPGVRWEYCNLTQC 105
Score = 90.9 bits (224), Expect = 1e-18
Identities = 45/130 (34%), Positives = 65/130 (50%), Gaps = 21/130 (16%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSY------RGKDLQENYCRNPRGEE 179
++C+ G G+ Y+G + T +G CQ W++ PH HS + L++NYCRNP G+
Sbjct: 1718 QDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDI 1777
Query: 180 GGPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRW 230
GPWC+T NP ++ CDIP C+ +VE C G G + H S W
Sbjct: 1778 NGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHS------W 1831
Query: 231 DHQTPHRHKF 240
Q R +F
Sbjct: 1832 PWQVSLRTRF 1841
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 115 bits (288), Expect = 4e-26
Identities = 62/186 (33%), Positives = 87/186 (46%), Gaps = 28/186 (15%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNPRGEEGG 181
NC G G +Y+G V+IT+SGI+CQ W S PH+ ++ G DLQEN+CRNP G
Sbjct: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
Query: 182 PWCFTSNPEVRYEVCDIPQCSE----------------------VECMTCNGESYRGLMD 219
PWC+T++P VR + C IP C + +C+ G+ Y+G +
Sbjct: 167 PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLA 226
Query: 220 HTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG-QPRPWCYTLDPHTRWEYC 278
T G C W + +N+CRNPDG + WCY + YC
Sbjct: 227 VTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYC 286
Query: 279 AIKTCE 284
+ CE
Sbjct: 287 DLNYCE 292
Score = 72.8 bits (177), Expect = 3e-13
Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 201 CSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C E C G +YRG ++ T SG CQ W + PH+ + +P +N+CRNPD
Sbjct: 103 CLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDS 162
Query: 261 QPR-PWCYTLDPHTRWEYCAIKTC 283
PWCYT DP R + C+I C
Sbjct: 163 STTGPWCYTTDPTVRRQECSIPVC 186
Score = 64.3 bits (155), Expect = 1e-10
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSS-----MIPHEHSYRGKDLQENYCRNPRGEE 179
+ C+ +G+ Y+G +++T G+ C W+S + H+ L EN+CRNP G+E
Sbjct: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269
Query: 180 GGPWCFTSNPEVRYEVCDIPQCSE 203
G WC+ + + CD+ C E
Sbjct: 270 EGVWCYVAGKPGDFGYCDLNYCEE 293
>gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 106 bits (265), Expect = 2e-23
Identities = 42/79 (53%), Positives = 50/79 (63%)
Query: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRP 264
EC NG+SYRG T +G+ CQ W TPH+H PE+YP+ G NYCRNPD P
Sbjct: 27 ECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNPDCSAGP 86
Query: 265 WCYTLDPHTRWEYCAIKTC 283
WCYT DP+ RWEYC + C
Sbjct: 87 WCYTTDPNVRWEYCNLTRC 105
Score = 86.3 bits (212), Expect = 3e-17
Identities = 39/86 (45%), Positives = 53/86 (61%), Gaps = 6/86 (6%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNPRGEE 179
++ C G+SY+GT T +G CQ WSSM PH+HS Y L NYCRNP
Sbjct: 25 VQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCS 83
Query: 180 GGPWCFTSNPEVRYEVCDIPQCSEVE 205
GPWC+T++P VR+E C++ +CS+ E
Sbjct: 84 AGPWCYTTDPNVRWEYCNLTRCSDDE 109
>gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 106 bits (265), Expect = 2e-23
Identities = 42/79 (53%), Positives = 50/79 (63%)
Query: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRP 264
EC NG+SYRG T +G+ CQ W TPH+H PE+YP+ G NYCRNPD P
Sbjct: 27 ECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNPDCSAGP 86
Query: 265 WCYTLDPHTRWEYCAIKTC 283
WCYT DP+ RWEYC + C
Sbjct: 87 WCYTTDPNVRWEYCNLTRC 105
Score = 86.3 bits (212), Expect = 3e-17
Identities = 39/86 (45%), Positives = 53/86 (61%), Gaps = 6/86 (6%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRNPRGEE 179
++ C G+SY+GT T +G CQ WSSM PH+HS Y L NYCRNP
Sbjct: 25 VQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCS 83
Query: 180 GGPWCFTSNPEVRYEVCDIPQCSEVE 205
GPWC+T++P VR+E C++ +CS+ E
Sbjct: 84 AGPWCYTTDPNVRWEYCNLTRCSDDE 109
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 104 bits (259), Expect = 1e-22
Identities = 59/173 (34%), Positives = 80/173 (46%), Gaps = 16/173 (9%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQ--------ENYCRNPRGEE 179
C +G SY+GT S +SG +C W+S + Y G+ NYCRNP +
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 185
Query: 180 GGPWCFTSNP-EVRYEVCDIPQCSE--VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 236
PWC+ + E C P CSE +C NG +YRG TESG C W+
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 245
Query: 237 RHKFLPERYPDKGFD---DNYCRNPDGQPRPWCYTL-DPHTRWEYCAIKTCET 285
+ + + NYCRNPDG +PWC+ L + WEYC + +C T
Sbjct: 246 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST 298
Score = 69.7 bits (169), Expect = 3e-12
Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 15/97 (15%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDL--------QENYCRNPRGE 178
+C G G +Y+GT S+T+SG C PW+SMI Y ++ + NYCRNP G
Sbjct: 214 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 272
Query: 179 EGGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESY 214
+ PWC N + +E CD+P CS TC Y
Sbjct: 273 DAKPWCHVLKNRRLTWEYCDVPSCS-----TCGLRQY 304
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 104 bits (259), Expect = 1e-22
Identities = 59/173 (34%), Positives = 80/173 (46%), Gaps = 16/173 (9%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQ--------ENYCRNPRGEE 179
C +G SY+GT S +SG +C W+S + Y G+ NYCRNP +
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 139
Query: 180 GGPWCFTSNP-EVRYEVCDIPQCSE--VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 236
PWC+ + E C P CSE +C NG +YRG TESG C W+
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 199
Query: 237 RHKFLPERYPDKGFD---DNYCRNPDGQPRPWCYTL-DPHTRWEYCAIKTCET 285
+ + + NYCRNPDG +PWC+ L + WEYC + +C T
Sbjct: 200 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST 252
Score = 69.7 bits (169), Expect = 3e-12
Identities = 37/97 (38%), Positives = 50/97 (51%), Gaps = 15/97 (15%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDL--------QENYCRNPRGE 178
+C G G +Y+GT S+T+SG C PW+SMI Y ++ + NYCRNP G
Sbjct: 168 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 226
Query: 179 EGGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESY 214
+ PWC N + +E CD+P CS TC Y
Sbjct: 227 DAKPWCHVLKNRRLTWEYCDVPSCS-----TCGLRQY 258
>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
Length = 943
Score = 94.4 bits (233), Expect = 1e-19
Identities = 41/80 (51%), Positives = 47/80 (58%), Gaps = 5/80 (6%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQE-----NYCRNPRGEEGGP 182
C G G Y+GT S TKSG +CQPW+ PH H D E YCRNP G+ GP
Sbjct: 316 CYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGP 375
Query: 183 WCFTSNPEVRYEVCDIPQCS 202
WCFT N VR E+CD+P CS
Sbjct: 376 WCFTQNKNVRMELCDVPSCS 395
Score = 71.6 bits (174), Expect = 7e-13
Identities = 32/80 (40%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
+C +G YRG T+SG CQ W Q PH H +P+ G YCRNP GQ
Sbjct: 315 QCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEG 374
Query: 264 PWCYTLDPHTRWEYCAIKTC 283
PWC+T + + R E C + +C
Sbjct: 375 PWCFTQNKNVRMELCDVPSC 394
>gi|134152686 receptor tyrosine kinase-like orphan receptor 1
isoform 2 [Homo sapiens]
Length = 393
Score = 85.1 bits (209), Expect = 6e-17
Identities = 37/88 (42%), Positives = 53/88 (60%), Gaps = 7/88 (7%)
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQE-----NYCRNP 175
NK++ C G Y+GTVS+TKSG +CQPW+S PH H++ E +YCRNP
Sbjct: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 203
++ PWCFT + + ++CDIP C +
Sbjct: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393
Score = 77.0 bits (188), Expect = 2e-14
Identities = 33/80 (41%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
Query: 264 PWCYTLDPHTRWEYCAIKTC 283
PWC+TLD + + + C I C
Sbjct: 372 PWCFTLDENFKSDLCDIPAC 391
>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
isoform 1 [Homo sapiens]
Length = 937
Score = 84.7 bits (208), Expect = 8e-17
Identities = 37/86 (43%), Positives = 52/86 (60%), Gaps = 7/86 (8%)
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQE-----NYCRNP 175
NK++ C G Y+GTVS+TKSG +CQPW+S PH H++ E +YCRNP
Sbjct: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
Query: 176 RGEEGGPWCFTSNPEVRYEVCDIPQC 201
++ PWCFT + + ++CDIP C
Sbjct: 366 GNQKEAPWCFTLDENFKSDLCDIPAC 391
Score = 78.2 bits (191), Expect = 8e-15
Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Query: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
Query: 264 PWCYTLDPHTRWEYCAIKTCET 285
PWC+TLD + + + C I C++
Sbjct: 372 PWCFTLDENFKSDLCDIPACDS 393
>gi|24041012 kringle-containing transmembrane protein 1 isoform 2
precursor [Homo sapiens]
Length = 492
Score = 67.8 bits (164), Expect = 1e-11
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 205 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 261
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
Query: 262 PRPWCYTLDPH--TRWEYCAIKTCE 284
PWCY + W+YC I C+
Sbjct: 93 VSPWCYVAEHEDGVYWKYCEIPACQ 117
Score = 48.1 bits (113), Expect = 9e-06
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSY------RGKDLQENYCRNPRGEE 179
C G Y+GT + T + G C W+ H ++ G + NYCRNP G+
Sbjct: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDV 93
Query: 180 GGPWCFTSNPE--VRYEVCDIPQC 201
PWC+ + E V ++ C+IP C
Sbjct: 94 -SPWCYVAEHEDGVYWKYCEIPAC 116
>gi|227116325 kringle-containing transmembrane protein 1 isoform 3
precursor [Homo sapiens]
Length = 458
Score = 67.8 bits (164), Expect = 1e-11
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 205 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 261
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
Query: 262 PRPWCYTLDPH--TRWEYCAIKTCE 284
PWCY + W+YC I C+
Sbjct: 93 VSPWCYVAEHEDGVYWKYCEIPACQ 117
Score = 48.1 bits (113), Expect = 9e-06
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSY------RGKDLQENYCRNPRGEE 179
C G Y+GT + T + G C W+ H ++ G + NYCRNP G+
Sbjct: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDV 93
Query: 180 GGPWCFTSNPE--VRYEVCDIPQC 201
PWC+ + E V ++ C+IP C
Sbjct: 94 -SPWCYVAEHEDGVYWKYCEIPAC 116
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 63.5 bits (153), Expect = 2e-10
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 196 CDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDN-Y 254
CD+ ++ C G SYRGL T SG CQ W + +R+ E+ + G + +
Sbjct: 209 CDVD--TKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRN-VTAEQARNWGLGGHAF 265
Query: 255 CRNPDGQPRPWCYTLD-PHTRWEYCAIKTCET 285
CRNPD RPWC+ L+ WEYC + C+T
Sbjct: 266 CRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQT 297
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 15/85 (17%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYRGKDLQE---------NYCRNPRG 177
+C G+G SY+G T SG CQPW+S E +YR ++ +CRNP
Sbjct: 216 SCYDGRGLSYRGLARTTLSGAPCQPWAS----EATYRNVTAEQARNWGLGGHAFCRNP-D 270
Query: 178 EEGGPWCFTSNPE-VRYEVCDIPQC 201
+ PWCF N + + +E CD+ QC
Sbjct: 271 NDIRPWCFVLNRDRLSWEYCDLAQC 295
>gi|13375642 kringle-containing transmembrane protein 2 isoform b
precursor [Homo sapiens]
Length = 420
Score = 61.2 bits (147), Expect = 1e-09
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 205 ECMTCNGESYRGLMDHTE---SGKICQRWDHQTPHRHKFLPERYPDKGFD-DNYCRNPDG 260
EC NG YRG + T +G+ C WD H + + + G N+CRNPDG
Sbjct: 35 ECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNPDG 94
Query: 261 QPRPWCYTLDPH--TRWEYCAIKTC 283
+PWCY + W YC I +C
Sbjct: 95 DVQPWCYVAETEEGIYWRYCDIPSC 119
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 12/88 (13%)
Query: 125 IRNCIIGKGRSYKGTVSITK---SGIKCQPWSSMIPHEHSYRGKDL------QENYCRNP 175
+ C G Y+G + T +G C W H +S N+CRNP
Sbjct: 33 LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNP 92
Query: 176 RGEEGGPWCFTSNPE--VRYEVCDIPQC 201
G+ PWC+ + E + + CDIP C
Sbjct: 93 DGDV-QPWCYVAETEEGIYWRYCDIPSC 119
>gi|27437008 kringle-containing transmembrane protein 2 isoform d
precursor [Homo sapiens]
Length = 462
Score = 61.2 bits (147), Expect = 1e-09
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 205 ECMTCNGESYRGLMDHTE---SGKICQRWDHQTPHRHKFLPERYPDKGFD-DNYCRNPDG 260
EC NG YRG + T +G+ C WD H + + + G N+CRNPDG
Sbjct: 35 ECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNPDG 94
Query: 261 QPRPWCYTLDPH--TRWEYCAIKTC 283
+PWCY + W YC I +C
Sbjct: 95 DVQPWCYVAETEEGIYWRYCDIPSC 119
Score = 40.0 bits (92), Expect = 0.002
Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 12/88 (13%)
Query: 125 IRNCIIGKGRSYKGTVSITK---SGIKCQPWSSMIPHEHSYRGKDL------QENYCRNP 175
+ C G Y+G + T +G C W H +S N+CRNP
Sbjct: 33 LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNP 92
Query: 176 RGEEGGPWCFTSNPE--VRYEVCDIPQC 201
G+ PWC+ + E + + CDIP C
Sbjct: 93 DGDV-QPWCYVAETEEGIYWRYCDIPSC 119
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 58.5 bits (140), Expect = 6e-09
Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 6/85 (7%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWD----HQTPHRHKFLPERYPDKGFDDNYCRNPDGQ 261
C NG YRG+ + SG C W+ +Q H G YCRNPD
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLG-PHAYCRNPDND 344
Query: 262 PRPWCYTL-DPHTRWEYCAIKTCET 285
RPWCY + D WEYC ++ CE+
Sbjct: 345 ERPWCYVVKDSALSWEYCRLEACES 369
Score = 46.6 bits (109), Expect = 2e-05
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMI----PHEHSYRGKDL----QENYCRNPRGEE 179
C +G G Y+G S + SG+ C W+S + H S L YCRNP +E
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
Query: 180 GGPWCF-TSNPEVRYEVCDIPQCSEV 204
PWC+ + + +E C + C +
Sbjct: 346 -RPWCYVVKDSALSWEYCRLEACESL 370
>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
Length = 560
Score = 56.6 bits (135), Expect = 2e-08
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 205 ECMTCNGESYRGLMDHTESGKICQRWDHQT---PHRHKFLPERYPDKGFDDNYCRNPDGQ 261
+C +G SYRG M+ T + C W+ + + F+ + + N+CRNPD
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 262 PRPWCY--TLDPHTRWEYCAIKTC 283
+PWC+ + +WEYC + C
Sbjct: 253 EKPWCFIKVTNDKVKWEYCDVSAC 276
Score = 54.7 bits (130), Expect = 9e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 11/86 (12%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSYR--GKDL------QENYCRNPRGE 178
+C +G G SY+G ++ T + C W+S + + +Y +D + N+CRNP +
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 179 EGGPWCF--TSNPEVRYEVCDIPQCS 202
E PWCF +N +V++E CD+ CS
Sbjct: 253 E-KPWCFIKVTNDKVKWEYCDVSACS 277
>gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo
sapiens]
Length = 299
Score = 50.1 bits (118), Expect = 2e-06
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 9/62 (14%)
Query: 171 YCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHT 221
YCRNP G+ GPWC+ NP ++ CDIP C+ +VE C G + H
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPRSIVGGCVAHP 66
Query: 222 ES 223
S
Sbjct: 67 HS 68
Score = 42.4 bits (98), Expect = 5e-04
Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 254 YCRNPDGQPR-PWCYTLDPHTRWEYCAIKTC 283
YCRNPDG PWCY ++P ++YC I C
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLC 37
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 46.2 bits (108), Expect = 3e-05
Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWD-----HQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C NG YRG G+ C W+ QT H H+ + NYCRNPD
Sbjct: 53 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHR--SDALQLGLGKHNYCRNPDN 110
Query: 261 QPRPWCY 267
+ RPWCY
Sbjct: 111 RRRPWCY 117
Score = 45.4 bits (106), Expect = 6e-05
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHE---HSYRGKDLQ-----ENYCRN 174
D + C G G Y+G S G C PW+S + H++R LQ NYCRN
Sbjct: 48 DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRN 107
Query: 175 PRGEEGGPWCF 185
P PWC+
Sbjct: 108 PDNRR-RPWCY 117
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 46.2 bits (108), Expect = 3e-05
Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRWD-----HQTPHRHKFLPERYPDKGFDDNYCRNPDG 260
C NG YRG G+ C W+ QT H H+ + NYCRNPD
Sbjct: 70 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHR--SDALQLGLGKHNYCRNPDN 127
Query: 261 QPRPWCY 267
+ RPWCY
Sbjct: 128 RRRPWCY 134
Score = 45.4 bits (106), Expect = 6e-05
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHE---HSYRGKDLQ-----ENYCRN 174
D + C G G Y+G S G C PW+S + H++R LQ NYCRN
Sbjct: 65 DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRN 124
Query: 175 PRGEEGGPWCF 185
P PWC+
Sbjct: 125 PDNRR-RPWCY 134
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 221 TESGKICQRWDHQTPHRHKFLPERYPD-KGFDDNYCRNPDGQPRPWCYTLDPHTR--WEY 277
T+ G C RW P + P + +G N+CR+PDG RPWC+ D + W Y
Sbjct: 103 TDFGAPCLRWAEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGY 162
Query: 278 C 278
C
Sbjct: 163 C 163
>gi|209571507 HGFL protein isoform 2 [Homo sapiens]
Length = 173
Score = 37.0 bits (84), Expect = 0.020
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPW----SSMIPHEHSYRGKDLQENYCRNPRGEEGGPW 183
C G Y+ + G++C W S + S G +YCRNP + GPW
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGN---HSYCRNPDEDPRGPW 81
Query: 184 CFTSN----PEVRYEVCDIPQCSE 203
C+ S PE R C+ +C E
Sbjct: 82 CYVSGEAGVPEKR--PCEDLRCPE 103
Score = 35.0 bits (79), Expect = 0.075
Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 7/64 (10%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRW-DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
C NG YR G C W D Q+ L + +YCRNPD PR
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDAQSG-----LASAPVSGAGNHSYCRNPDEDPRG 79
Query: 264 PWCY 267
PWCY
Sbjct: 80 PWCY 83
>gi|51317358 HGFL protein isoform 1 [Homo sapiens]
Length = 263
Score = 37.0 bits (84), Expect = 0.020
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPW----SSMIPHEHSYRGKDLQENYCRNPRGEEGGPW 183
C G Y+ + G++C W S + S G +YCRNP + GPW
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGN---HSYCRNPDEDPRGPW 81
Query: 184 CFTSN----PEVRYEVCDIPQCSE 203
C+ S PE R C+ +C E
Sbjct: 82 CYVSGEAGVPEKR--PCEDLRCPE 103
Score = 35.0 bits (79), Expect = 0.075
Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 7/64 (10%)
Query: 206 CMTCNGESYRGLMDHTESGKICQRW-DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 263
C NG YR G C W D Q+ L + +YCRNPD PR
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDAQSG-----LASAPVSGAGNHSYCRNPDEDPRG 79
Query: 264 PWCY 267
PWCY
Sbjct: 80 PWCY 83
>gi|40806187 ADAM metallopeptidase with thrombospondin type 1 motif,
18 preproprotein [Homo sapiens]
Length = 1221
Score = 35.4 bits (80), Expect = 0.058
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 9/60 (15%)
Query: 164 GKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE-------VECMTCNGESYRG 216
G QE +C NP+ + GG +C S+ Y++C+I C+E +C N + +RG
Sbjct: 608 GVKFQERHCNNPKPQYGGLFCPGSSR--IYQLCNINPCNENSLDFRAQQCAEYNSKPFRG 665
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,928,606
Number of Sequences: 37866
Number of extensions: 647033
Number of successful extensions: 1380
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1133
Number of HSP's gapped (non-prelim): 108
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.