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Search of human proteins with 58533163
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
sapiens]
(290 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s... 637 0.0
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho... 633 0.0
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s... 621 e-178
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s... 617 e-177
gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo s... 443 e-125
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 242 2e-64
gi|4505881 plasminogen [Homo sapiens] 233 1e-61
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 184 8e-47
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 120 1e-27
gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 106 2e-23
gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens] 106 2e-23
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 102 4e-22
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 102 4e-22
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec... 93 2e-19
gi|134152686 receptor tyrosine kinase-like orphan receptor 1 iso... 88 1e-17
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso... 87 1e-17
gi|24041012 kringle-containing transmembrane protein 1 isoform 2... 68 1e-11
gi|227116325 kringle-containing transmembrane protein 1 isoform ... 68 1e-11
gi|145275213 coagulation factor XII precursor [Homo sapiens] 64 2e-10
gi|13375642 kringle-containing transmembrane protein 2 isoform b... 61 1e-09
gi|27437008 kringle-containing transmembrane protein 2 isoform d... 61 1e-09
gi|4504383 HGF activator preproprotein [Homo sapiens] 59 7e-09
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi... 57 2e-08
gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo ... 50 2e-06
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 46 3e-05
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 46 3e-05
gi|4506143 neurotrypsin precursor [Homo sapiens] 46 3e-05
gi|209571507 HGFL protein isoform 2 [Homo sapiens] 38 0.012
gi|51317358 HGFL protein isoform 1 [Homo sapiens] 38 0.012
gi|40806187 ADAM metallopeptidase with thrombospondin type 1 mot... 35 0.059
>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
sapiens]
Length = 290
Score = 637 bits (1642), Expect = 0.0
Identities = 290/290 (100%), Positives = 290/290 (100%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
Query: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET
Sbjct: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
sapiens]
Length = 728
Score = 633 bits (1632), Expect = 0.0
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
Query: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC
Sbjct: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
Score = 164 bits (415), Expect = 8e-41
Identities = 75/175 (42%), Positives = 96/175 (54%), Gaps = 14/175 (8%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C+ G SY+G + T+SG CQ W PH H FLP Y K +NYCRNP G+ P
Sbjct: 211 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR-P 269
Query: 188 WCFTSNPEVRYEVCDIPQCSE------------VECMTCNGESYRGLMDHTESGKICQRW 235
WC+T +P R+E C I C++ EC+ GE YRG ++ +G CQRW
Sbjct: 270 WCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRW 329
Query: 236 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCA-IKTCE 289
D Q PH H PE + K +NYCRNPDG PWC+T DP+ R YC+ I C+
Sbjct: 330 DSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD 384
Score = 158 bits (400), Expect = 5e-39
Identities = 78/170 (45%), Positives = 97/170 (57%), Gaps = 12/170 (7%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
CI G+G Y+GTV+ +GI CQ W S PHEH P +++ KDL+ENYCRNP G E P
Sbjct: 305 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSES-P 363
Query: 188 WCFTSNPEVRYEVCD-IPQCSEV---ECMTCNGESYRGLMDHTESGKICQRWDHQTP--H 241
WCFT++P +R C IP C +C NG++Y G + T SG C WD H
Sbjct: 364 WCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH 423
Query: 242 RHKFLPERYPDKG-FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCE 289
RH F PD ++NYCRNPD PWCYT +P W+YC I CE
Sbjct: 424 RHIFWE---PDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCE 470
Score = 74.7 bits (182), Expect = 9e-14
Identities = 30/81 (37%), Positives = 45/81 (55%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
++C G G++Y G +S T+SG+ C W + H + L ENYCRNP +
Sbjct: 389 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 448
Query: 186 GPWCFTSNPEVRYEVCDIPQC 206
GPWC+T NP + ++ C I +C
Sbjct: 449 GPWCYTGNPLIPWDYCPISRC 469
>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
sapiens]
Length = 285
Score = 621 bits (1601), Expect = e-178
Identities = 285/290 (98%), Positives = 285/290 (98%), Gaps = 5/290 (1%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175
Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 235
Query: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET
Sbjct: 236 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 285
>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
Length = 723
Score = 617 bits (1591), Expect = e-177
Identities = 283/288 (98%), Positives = 283/288 (98%), Gaps = 5/288 (1%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175
Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 240
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
Sbjct: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP 235
Query: 241 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC
Sbjct: 236 HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 283
Score = 164 bits (415), Expect = 8e-41
Identities = 75/175 (42%), Positives = 96/175 (54%), Gaps = 14/175 (8%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C+ G SY+G + T+SG CQ W PH H FLP Y K +NYCRNP G+ P
Sbjct: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR-P 264
Query: 188 WCFTSNPEVRYEVCDIPQCSE------------VECMTCNGESYRGLMDHTESGKICQRW 235
WC+T +P R+E C I C++ EC+ GE YRG ++ +G CQRW
Sbjct: 265 WCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRW 324
Query: 236 DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCA-IKTCE 289
D Q PH H PE + K +NYCRNPDG PWC+T DP+ R YC+ I C+
Sbjct: 325 DSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCD 379
Score = 158 bits (400), Expect = 5e-39
Identities = 78/170 (45%), Positives = 97/170 (57%), Gaps = 12/170 (7%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
CI G+G Y+GTV+ +GI CQ W S PHEH P +++ KDL+ENYCRNP G E P
Sbjct: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSES-P 358
Query: 188 WCFTSNPEVRYEVCD-IPQCSEV---ECMTCNGESYRGLMDHTESGKICQRWDHQTP--H 241
WCFT++P +R C IP C +C NG++Y G + T SG C WD H
Sbjct: 359 WCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH 418
Query: 242 RHKFLPERYPDKG-FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCE 289
RH F PD ++NYCRNPD PWCYT +P W+YC I CE
Sbjct: 419 RHIFWE---PDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCE 465
Score = 74.7 bits (182), Expect = 9e-14
Identities = 30/81 (37%), Positives = 45/81 (55%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
++C G G++Y G +S T+SG+ C W + H + L ENYCRNP +
Sbjct: 384 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 443
Query: 186 GPWCFTSNPEVRYEVCDIPQC 206
GPWC+T NP + ++ C I +C
Sbjct: 444 GPWCYTGNPLIPWDYCPISRC 464
>gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo
sapiens]
Length = 210
Score = 443 bits (1139), Expect = e-125
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1 MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
Query: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61 TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
RGEEGGPWCFTSNPEVRYEVCDIPQCSE
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
Score = 85.1 bits (209), Expect = 7e-17
Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 211 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP-RP 269
C+ G SY+G + T+SG CQ W PH H FLP Y K +NYCRNP G+ P
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
Query: 270 WCYTLDPHTRWEYCAIKTC 288
WC+T +P R+E C I C
Sbjct: 188 WCFTSNPEVRYEVCDIPQC 206
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 242 bits (618), Expect = 2e-64
Identities = 118/289 (40%), Positives = 166/289 (57%), Gaps = 13/289 (4%)
Query: 2 WVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIKT 61
WVT PA + + L LLL G +R+ +++F+ T L + A+
Sbjct: 5 WVTVQPPARRMGWLPLLLLLTQCL-----GVPGQRSPLNDFQVLRGTELQHLLHAVVPGP 59
Query: 62 KKVNTAD--QCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLY 119
+ + AD +CA RC G C+AF ++ + C P+ S + DL+
Sbjct: 60 WQEDVADAEECAGRC----GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLF 115
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
+ KDY+R CI+ G Y+GT++ T G+ CQ WS P++H + P+ G L+EN+CRN
Sbjct: 116 QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNG--LEENFCRN 173
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQT 239
P G+ GGPWC+T++P VR++ C I C E C+ CNGE YRG +D TESG+ CQRWD Q
Sbjct: 174 PDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQH 233
Query: 240 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTC 288
PH+H F P ++ D+G DDNYCRNPDG RPWCYT DP E+C + C
Sbjct: 234 PHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRC 282
Score = 172 bits (435), Expect = 4e-43
Identities = 76/168 (45%), Positives = 102/168 (60%), Gaps = 7/168 (4%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG 186
+C GKG Y+GT + T +G+ CQ W + IPH+H F P Y KDL+EN+CRNP G E
Sbjct: 296 SCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSE-A 354
Query: 187 PWCFTSNPEVRYEVC-DIPQCSE----VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 241
PWCFT P +R C I +C++ +C GE YRG + T G CQRW +TPH
Sbjct: 355 PWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPH 414
Query: 242 RHKFLPERYPDKGFDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTC 288
+ +F P ++N+CRNPDG PWCYT+DP T ++YCA++ C
Sbjct: 415 KPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRC 462
Score = 170 bits (431), Expect = 1e-42
Identities = 75/172 (43%), Positives = 100/172 (58%), Gaps = 12/172 (6%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C+ G Y+G V T+SG +CQ W PH+H F P + + L +NYCRNP G E P
Sbjct: 205 CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSER-P 263
Query: 188 WCFTSNPEVRYEVCDIPQCSE----------VECMTCNGESYRGLMDHTESGKICQRWDH 237
WC+T++P++ E CD+P+C V C GE YRG + T +G CQRWD
Sbjct: 264 WCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDA 323
Query: 238 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYC-AIKTC 288
Q PH+H+F PE+Y K +N+CRNPDG PWC+TL P R +C I+ C
Sbjct: 324 QIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRRC 375
Score = 89.0 bits (219), Expect = 5e-18
Identities = 34/83 (40%), Positives = 54/83 (65%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
++C G G Y+GTVS T+ G++CQ WS+ PH+ F +S L+EN+CRNP G+
Sbjct: 382 QDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSH 441
Query: 186 GPWCFTSNPEVRYEVCDIPQCSE 208
GPWC+T +P ++ C + +C++
Sbjct: 442 GPWCYTMDPRTPFDYCALRRCAD 464
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 233 bits (595), Expect = 1e-61
Identities = 105/233 (45%), Positives = 148/233 (63%), Gaps = 8/233 (3%)
Query: 61 TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
TKK + ++CA +C ++ FTC+AF + +QC+ N SS + + +
Sbjct: 37 TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92
Query: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177
L+E K Y+ C G G++Y+GT+S TK+GI CQ WSS PH F P+++ + L+ENYC
Sbjct: 93 LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152
Query: 178 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDH 237
RNP + GPWC+T++PE RY+ CDI +C E ECM C+GE+Y G + T SG CQ WD
Sbjct: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE-ECMHCSGENYDGKISKTMSGLECQAWDS 211
Query: 238 QTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
Q+PH H ++P ++P+K NYCRNPD + RPWC+T DP+ RWE C I C T
Sbjct: 212 QSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTT 264
Score = 189 bits (481), Expect = 2e-48
Identities = 80/171 (46%), Positives = 109/171 (63%), Gaps = 9/171 (5%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C+ G +Y G +S T SG++CQ W S PH H ++PS + K+L++NYCRNP E P
Sbjct: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243
Query: 188 WCFTSNPEVRYEVCDIPQCSE--------VECMTCNGESYRGLMDHTESGKICQRWDHQT 239
WCFT++P R+E+CDIP+C+ +C+ GE+YRG + T SG CQ W QT
Sbjct: 244 WCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQT 303
Query: 240 PHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCET 290
PH H PE +P K D+NYCRNPDG+ PWC+T + RWEYC I +C++
Sbjct: 304 PHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDS 354
Score = 184 bits (466), Expect = 1e-46
Identities = 81/181 (44%), Positives = 103/181 (56%), Gaps = 21/181 (11%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C+ G G +Y+G V++T SG CQ WS+ PH H+ P ++ K+L ENYCRNP G+ P
Sbjct: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRA-P 333
Query: 188 WCFTSNPEVRYEVCDIPQCSEV--------------------ECMTCNGESYRGLMDHTE 227
WC T+N +VR+E C IP C +C +G+SYRG T
Sbjct: 334 WCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT 393
Query: 228 SGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKT 287
+GK CQ W TPHRH+ PE YP+ G NYCRNPD PWC+T DP RWEYC +K
Sbjct: 394 TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453
Query: 288 C 288
C
Sbjct: 454 C 454
Score = 170 bits (431), Expect = 1e-42
Identities = 82/188 (43%), Positives = 105/188 (55%), Gaps = 25/188 (13%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
+++C G G+SY+GT S T +G KCQ WSSM PH H P +Y L NYCRNP ++
Sbjct: 374 VQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK 433
Query: 185 GGPWCFTSNPEVRYEVCDIPQC----------------------SEVECMTCNGESYRGL 222
GPWCFT++P VR+E C++ +C SE +CM NG+ YRG
Sbjct: 434 -GPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGK 492
Query: 223 MDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQ-PRPWCYTLDPHTRW 280
T +G CQ W Q PHRH F PE P G + NYCRNPDG PWCYT +P +
Sbjct: 493 RATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLY 552
Query: 281 EYCAIKTC 288
+YC + C
Sbjct: 553 DYCDVPQC 560
Score = 102 bits (255), Expect = 3e-22
Identities = 49/129 (37%), Positives = 69/129 (53%), Gaps = 16/129 (12%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNPRGEEG 185
+C+ G G+ Y+G + T +G CQ W++ PH HS F P + L++NYCRNP G+ G
Sbjct: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539
Query: 186 GPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRWD 236
GPWC+T+NP Y+ CD+PQC+ +VE C G G + H S W
Sbjct: 540 GPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHS------WP 593
Query: 237 HQTPHRHKF 245
Q R +F
Sbjct: 594 WQVSLRTRF 602
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 184 bits (467), Expect = 8e-47
Identities = 86/201 (42%), Positives = 107/201 (53%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E +++C G GRSY+G S T +G CQ WSSMIPH H P +Y L ENYCRN
Sbjct: 1494 EKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRN 1553
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P + PWC+T++P VR+E C++ QCSE E
Sbjct: 1554 PDSGK-QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPV 1612
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPHRH+ PE YP+ G NYCRNPD
Sbjct: 1613 VRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADT 1672
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
PWC+T+DP RWEYC + C
Sbjct: 1673 GPWCFTMDPSIRWEYCNLTRC 1693
Score = 181 bits (459), Expect = 7e-46
Identities = 83/201 (41%), Positives = 107/201 (53%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT IT +G CQ WSSM PH HS P+ Y L +NYCRN
Sbjct: 932 EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P PWC+T++P VR+E C++ +CS+ E
Sbjct: 992 P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C G+SYRG T +G+ CQ W TPH+H PE YP+ G NYCRNPD +
Sbjct: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
RPWCYT+DP RWEYC + C
Sbjct: 1111 RPWCYTMDPSVRWEYCNLTQC 1131
Score = 173 bits (438), Expect = 2e-43
Identities = 81/201 (40%), Positives = 104/201 (51%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
EN +++C G G+SY+GT+S T +G CQ WSSM PH H +P Y L NYCRN
Sbjct: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P E PWC+T +P VR+E C++ +C E
Sbjct: 1440 PDAEIR-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPV 1498
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C +G SYRG+ T +G+ CQ W PH H+ PE YP+ G +NYCRNPD
Sbjct: 1499 VQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGK 1558
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
+PWCYT DP RWEYC + C
Sbjct: 1559 QPWCYTTDPCVRWEYCNLTQC 1579
Score = 172 bits (437), Expect = 2e-43
Identities = 82/203 (40%), Positives = 105/203 (51%), Gaps = 33/203 (16%)
Query: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177
L E +++C G+SY+GT S T +G CQ WSSM PH+HS P +Y L NYC
Sbjct: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
Query: 178 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE--------------------------- 210
RNP E PWC+T +P VR+E C++ QC E
Sbjct: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
Query: 211 -----CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 265
C +G+SYRG T +G+ CQ W TPH H+ E YP+ G NYCRNPD
Sbjct: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
Query: 266 QPRPWCYTLDPHTRWEYCAIKTC 288
+ PWCYT+DP+ RWEYC + C
Sbjct: 1223 EISPWCYTMDPNVRWEYCNLTQC 1245
Score = 171 bits (433), Expect = 7e-43
Identities = 80/193 (41%), Positives = 101/193 (52%), Gaps = 25/193 (12%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E +++C G G+SY+G+ S T +G CQ WSSM PH H Y L NYCRN
Sbjct: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE------------------------CMTCN 215
P E PWC+T +P VR+E C++ QC E C +
Sbjct: 1220 PDAEIS-PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
Query: 216 GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLD 275
G+SYRG T +G+ CQ W TPH H+ E YP+ G NYCRNPD + RPWCYT+D
Sbjct: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
Query: 276 PHTRWEYCAIKTC 288
P RWEYC + C
Sbjct: 1339 PSVRWEYCNLTQC 1351
Score = 171 bits (433), Expect = 7e-43
Identities = 80/201 (39%), Positives = 104/201 (51%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E +++C G G+SY+G+ S T +G CQ WSSM PH H Y L NYCRN
Sbjct: 1266 EQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1325
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P E PWC+T +P VR+E C++ QC +E
Sbjct: 1326 PDAEIR-PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTG 1384
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C +G+SYRG + T +G+ CQ W TPH H+ +P YP+ G NYCRNPD +
Sbjct: 1385 VQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEI 1444
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
RPWCYT+DP RWEYC + C
Sbjct: 1445 RPWCYTMDPSVRWEYCNLTRC 1465
Score = 169 bits (427), Expect = 3e-42
Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS P Y L NYCRN
Sbjct: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 194 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
P+CYT DP RWEYC + C
Sbjct: 313 APYCYTRDPGVRWEYCNLTQC 333
Score = 169 bits (427), Expect = 3e-42
Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS P Y L NYCRN
Sbjct: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 308 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
P+CYT DP RWEYC + C
Sbjct: 427 APYCYTRDPGVRWEYCNLTQC 447
Score = 169 bits (427), Expect = 3e-42
Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS P Y L NYCRN
Sbjct: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 422 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
P+CYT DP RWEYC + C
Sbjct: 541 APYCYTRDPGVRWEYCNLTQC 561
Score = 169 bits (427), Expect = 3e-42
Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS P Y L NYCRN
Sbjct: 476 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 536 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 595 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 654
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
P+CYT DP RWEYC + C
Sbjct: 655 APYCYTRDPGVRWEYCNLTQC 675
Score = 169 bits (427), Expect = 3e-42
Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS P Y L NYCRN
Sbjct: 590 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 650 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 709 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
P+CYT DP RWEYC + C
Sbjct: 769 APYCYTRDPGVRWEYCNLTQC 789
Score = 168 bits (426), Expect = 4e-42
Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS P Y L NYCRN
Sbjct: 704 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 764 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 823 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
P+CYT DP RWEYC + C
Sbjct: 883 APYCYTRDPSVRWEYCNLTQC 903
Score = 168 bits (426), Expect = 4e-42
Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E + ++ C G G+SY+GT S T +G CQ WSSM PH HS P Y L NYCRN
Sbjct: 818 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 877
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEV------------------------------ 209
P P+C+T +P VR+E C++ QCS+
Sbjct: 878 P-DPVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPG 936
Query: 210 --ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
EC NG+SY+G T +G+ CQ W TPH H P YP+ G NYCRNPD
Sbjct: 937 VQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVA 996
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
PWCYT DP RWEYC + C
Sbjct: 997 APWCYTTDPSVRWEYCNLTRC 1017
Score = 166 bits (421), Expect = 2e-41
Identities = 80/201 (39%), Positives = 102/201 (50%), Gaps = 33/201 (16%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E +++C G G+SY+GT S T +G CQ WSSM PH+H+ +Y L NYCRN
Sbjct: 20 EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210
P P+C+T +P VR+E C++ QCS+ E
Sbjct: 80 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
Query: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267
C NG+SYRG T +G+ CQ W TPH H PE YP+ G NYCRNPD
Sbjct: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
Query: 268 RPWCYTLDPHTRWEYCAIKTC 288
P+CYT DP RWEYC + C
Sbjct: 199 APYCYTRDPGVRWEYCNLTQC 219
Score = 166 bits (420), Expect = 2e-41
Identities = 81/193 (41%), Positives = 102/193 (52%), Gaps = 25/193 (12%)
Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
E +R C G G+SY+GT S T +G CQ WSSM PH H P +Y L NYCRN
Sbjct: 1608 EQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRN 1667
Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------CMTCNGE 217
P + GPWCFT +P +R+E C++ +CS+ E CM NG+
Sbjct: 1668 PDADT-GPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGK 1726
Query: 218 SYRGLMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQPR-PWCYTLD 275
YRG T +G CQ W Q PHRH F+P G + NYCRNPDG PWCYT++
Sbjct: 1727 GYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMN 1786
Query: 276 PHTRWEYCAIKTC 288
P ++YC I C
Sbjct: 1787 PRKLFDYCDIPLC 1799
Score = 99.0 bits (245), Expect = 4e-21
Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 16/130 (12%)
Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNPRGEE 184
++C+ G G+ Y+G + T +G CQ W++ PH HS F+P + + L++NYCRNP G+
Sbjct: 1718 QDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDI 1777
Query: 185 GGPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRW 235
GPWC+T NP ++ CDIP C+ +VE C G G + H S W
Sbjct: 1778 NGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHS------W 1831
Query: 236 DHQTPHRHKF 245
Q R +F
Sbjct: 1832 PWQVSLRTRF 1841
Score = 95.1 bits (235), Expect = 6e-20
Identities = 41/87 (47%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Query: 204 PQCSEV--ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCR 261
P+ S V +C +G+SYRG T +G+ CQ W TPH+H E YP+ G NYCR
Sbjct: 19 PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
Query: 262 NPDGQPRPWCYTLDPHTRWEYCAIKTC 288
NPD P+CYT DP RWEYC + C
Sbjct: 79 NPDAVAAPYCYTRDPGVRWEYCNLTQC 105
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 120 bits (301), Expect = 1e-27
Identities = 62/186 (33%), Positives = 88/186 (47%), Gaps = 23/186 (12%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG 186
NC G G +Y+G V+IT+SGI+CQ W S PH+ +++ G DLQEN+CRNP G
Sbjct: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166
Query: 187 PWCFTSNPEVRYEVCDIPQCSE----------------------VECMTCNGESYRGLMD 224
PWC+T++P VR + C IP C + +C+ G+ Y+G +
Sbjct: 167 PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLA 226
Query: 225 HTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG-QPRPWCYTLDPHTRWEYC 283
T G C W + +N+CRNPDG + WCY + YC
Sbjct: 227 VTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYC 286
Query: 284 AIKTCE 289
+ CE
Sbjct: 287 DLNYCE 292
Score = 72.8 bits (177), Expect = 3e-13
Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 206 CSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 265
C E C G +YRG ++ T SG CQ W + PH+ + +P +N+CRNPD
Sbjct: 103 CLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDS 162
Query: 266 QPR-PWCYTLDPHTRWEYCAIKTC 288
PWCYT DP R + C+I C
Sbjct: 163 STTGPWCYTTDPTVRRQECSIPVC 186
Score = 62.4 bits (150), Expect = 5e-10
Identities = 26/84 (30%), Positives = 42/84 (50%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
+ C+ +G+ Y+G +++T G+ C W+S S L EN+CRNP G+E
Sbjct: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269
Query: 185 GGPWCFTSNPEVRYEVCDIPQCSE 208
G WC+ + + CD+ C E
Sbjct: 270 EGVWCYVAGKPGDFGYCDLNYCEE 293
>gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 106 bits (265), Expect = 2e-23
Identities = 42/79 (53%), Positives = 50/79 (63%)
Query: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRP 269
EC NG+SYRG T +G+ CQ W TPH+H PE+YP+ G NYCRNPD P
Sbjct: 27 ECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNPDCSAGP 86
Query: 270 WCYTLDPHTRWEYCAIKTC 288
WCYT DP+ RWEYC + C
Sbjct: 87 WCYTTDPNVRWEYCNLTRC 105
Score = 93.6 bits (231), Expect = 2e-19
Identities = 40/86 (46%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
++ C G+SY+GT T +G CQ WSSM PH+HS P Y L NYCRNP
Sbjct: 25 VQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCS 83
Query: 185 GGPWCFTSNPEVRYEVCDIPQCSEVE 210
GPWC+T++P VR+E C++ +CS+ E
Sbjct: 84 AGPWCYTTDPNVRWEYCNLTRCSDDE 109
>gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
Length = 132
Score = 106 bits (265), Expect = 2e-23
Identities = 42/79 (53%), Positives = 50/79 (63%)
Query: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRP 269
EC NG+SYRG T +G+ CQ W TPH+H PE+YP+ G NYCRNPD P
Sbjct: 27 ECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNPDCSAGP 86
Query: 270 WCYTLDPHTRWEYCAIKTC 288
WCYT DP+ RWEYC + C
Sbjct: 87 WCYTTDPNVRWEYCNLTRC 105
Score = 93.6 bits (231), Expect = 2e-19
Identities = 40/86 (46%), Positives = 54/86 (62%), Gaps = 1/86 (1%)
Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
++ C G+SY+GT T +G CQ WSSM PH+HS P Y L NYCRNP
Sbjct: 25 VQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCS 83
Query: 185 GGPWCFTSNPEVRYEVCDIPQCSEVE 210
GPWC+T++P VR+E C++ +CS+ E
Sbjct: 84 AGPWCYTTDPNVRWEYCNLTRCSDDE 109
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 102 bits (254), Expect = 4e-22
Identities = 59/173 (34%), Positives = 81/173 (46%), Gaps = 11/173 (6%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFL---PSSYRGKDLQENYCRNPRGEE 184
C +G SY+GT S +SG +C W+S + + P + R NYCRNP +
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 185
Query: 185 GGPWCFTSNP-EVRYEVCDIPQCSE--VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 241
PWC+ + E C P CSE +C NG +YRG TESG C W+
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 245
Query: 242 RHKFLPERYPDKGFD---DNYCRNPDGQPRPWCYTL-DPHTRWEYCAIKTCET 290
+ + + NYCRNPDG +PWC+ L + WEYC + +C T
Sbjct: 246 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST 298
Score = 70.1 bits (170), Expect = 2e-12
Identities = 37/97 (38%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDL---QENYCRNPRGE 183
+C G G +Y+GT S+T+SG C PW+SMI + + + L + NYCRNP G
Sbjct: 214 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 272
Query: 184 EGGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESY 219
+ PWC N + +E CD+P CS TC Y
Sbjct: 273 DAKPWCHVLKNRRLTWEYCDVPSCS-----TCGLRQY 304
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 102 bits (254), Expect = 4e-22
Identities = 59/173 (34%), Positives = 81/173 (46%), Gaps = 11/173 (6%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFL---PSSYRGKDLQENYCRNPRGEE 184
C +G SY+GT S +SG +C W+S + + P + R NYCRNP +
Sbjct: 81 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 139
Query: 185 GGPWCFTSNP-EVRYEVCDIPQCSE--VECMTCNGESYRGLMDHTESGKICQRWDHQTPH 241
PWC+ + E C P CSE +C NG +YRG TESG C W+
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILI 199
Query: 242 RHKFLPERYPDKGFD---DNYCRNPDGQPRPWCYTL-DPHTRWEYCAIKTCET 290
+ + + NYCRNPDG +PWC+ L + WEYC + +C T
Sbjct: 200 GKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST 252
Score = 70.1 bits (170), Expect = 2e-12
Identities = 37/97 (38%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDL---QENYCRNPRGE 183
+C G G +Y+GT S+T+SG C PW+SMI + + + L + NYCRNP G
Sbjct: 168 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 226
Query: 184 EGGPWCFT-SNPEVRYEVCDIPQCSEVECMTCNGESY 219
+ PWC N + +E CD+P CS TC Y
Sbjct: 227 DAKPWCHVLKNRRLTWEYCDVPSCS-----TCGLRQY 258
>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
precursor [Homo sapiens]
Length = 943
Score = 93.2 bits (230), Expect = 2e-19
Identities = 39/80 (48%), Positives = 47/80 (58%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C G G Y+GT S TKSG +CQPW+ PH H + + YCRNP G+ GP
Sbjct: 316 CYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGP 375
Query: 188 WCFTSNPEVRYEVCDIPQCS 207
WCFT N VR E+CD+P CS
Sbjct: 376 WCFTQNKNVRMELCDVPSCS 395
Score = 71.6 bits (174), Expect = 7e-13
Identities = 32/80 (40%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 268
+C +G YRG T+SG CQ W Q PH H +P+ G YCRNP GQ
Sbjct: 315 QCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEG 374
Query: 269 PWCYTLDPHTRWEYCAIKTC 288
PWC+T + + R E C + +C
Sbjct: 375 PWCFTQNKNVRMELCDVPSC 394
>gi|134152686 receptor tyrosine kinase-like orphan receptor 1
isoform 2 [Homo sapiens]
Length = 393
Score = 87.8 bits (216), Expect = 1e-17
Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
NK++ C G Y+GTVS+TKSG +CQPW+S PH H+F + + +YCRNP
Sbjct: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
++ PWCFT + + ++CDIP C +
Sbjct: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393
Score = 77.0 bits (188), Expect = 2e-14
Identities = 33/80 (41%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 268
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
Query: 269 PWCYTLDPHTRWEYCAIKTC 288
PWC+TLD + + + C I C
Sbjct: 372 PWCFTLDENFKSDLCDIPAC 391
>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
isoform 1 [Homo sapiens]
Length = 937
Score = 87.4 bits (215), Expect = 1e-17
Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 2/86 (2%)
Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
NK++ C G Y+GTVS+TKSG +CQPW+S PH H+F + + +YCRNP
Sbjct: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365
Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQC 206
++ PWCFT + + ++CDIP C
Sbjct: 366 GNQKEAPWCFTLDENFKSDLCDIPAC 391
Score = 78.2 bits (191), Expect = 8e-15
Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Query: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 268
+C G YRG + T+SG+ CQ W+ Q PH H F R+P+ +YCRNP Q
Sbjct: 312 KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEA 371
Query: 269 PWCYTLDPHTRWEYCAIKTCET 290
PWC+TLD + + + C I C++
Sbjct: 372 PWCFTLDENFKSDLCDIPACDS 393
>gi|24041012 kringle-containing transmembrane protein 1 isoform 2
precursor [Homo sapiens]
Length = 492
Score = 67.8 bits (164), Expect = 1e-11
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 210 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 266
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
Query: 267 PRPWCYTLDPH--TRWEYCAIKTCE 289
PWCY + W+YC I C+
Sbjct: 93 VSPWCYVAEHEDGVYWKYCEIPACQ 117
Score = 50.8 bits (120), Expect = 1e-06
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 8/85 (9%)
Query: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSFL--PSSYRGKDLQENYCRNPRGE 183
C G Y+GT + T + G C W+ H ++ L P+ G + NYCRNP G+
Sbjct: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG-EHNYCRNPDGD 92
Query: 184 EGGPWCFTSNPE--VRYEVCDIPQC 206
PWC+ + E V ++ C+IP C
Sbjct: 93 V-SPWCYVAEHEDGVYWKYCEIPAC 116
>gi|227116325 kringle-containing transmembrane protein 1 isoform 3
precursor [Homo sapiens]
Length = 458
Score = 67.8 bits (164), Expect = 1e-11
Identities = 33/85 (38%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 210 ECMTCNGESYRGLMDHT--ESGKICQRWDHQTPHRHKFLPERYPDKGFDD-NYCRNPDGQ 266
EC T NG YRG + T + GK C W+ H + L + G + NYCRNPDG
Sbjct: 33 ECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGD 92
Query: 267 PRPWCYTLDPH--TRWEYCAIKTCE 289
PWCY + W+YC I C+
Sbjct: 93 VSPWCYVAEHEDGVYWKYCEIPACQ 117
Score = 50.8 bits (120), Expect = 1e-06
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 8/85 (9%)
Query: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSFL--PSSYRGKDLQENYCRNPRGE 183
C G Y+GT + T + G C W+ H ++ L P+ G + NYCRNP G+
Sbjct: 34 CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG-EHNYCRNPDGD 92
Query: 184 EGGPWCFTSNPE--VRYEVCDIPQC 206
PWC+ + E V ++ C+IP C
Sbjct: 93 V-SPWCYVAEHEDGVYWKYCEIPAC 116
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 63.5 bits (153), Expect = 2e-10
Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 201 CDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDN-Y 259
CD+ ++ C G SYRGL T SG CQ W + +R+ E+ + G + +
Sbjct: 209 CDVD--TKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRN-VTAEQARNWGLGGHAF 265
Query: 260 CRNPDGQPRPWCYTLD-PHTRWEYCAIKTCET 290
CRNPD RPWC+ L+ WEYC + C+T
Sbjct: 266 CRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQT 297
Score = 55.5 bits (132), Expect = 6e-08
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG 186
+C G+G SY+G T SG CQPW+S + + + +CRNP +
Sbjct: 216 SCYDGRGLSYRGLARTTLSGAPCQPWASEATYRNVTAEQARNWGLGGHAFCRNP-DNDIR 274
Query: 187 PWCFTSNPE-VRYEVCDIPQC 206
PWCF N + + +E CD+ QC
Sbjct: 275 PWCFVLNRDRLSWEYCDLAQC 295
>gi|13375642 kringle-containing transmembrane protein 2 isoform b
precursor [Homo sapiens]
Length = 420
Score = 61.2 bits (147), Expect = 1e-09
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 210 ECMTCNGESYRGLMDHTE---SGKICQRWDHQTPHRHKFLPERYPDKGFD-DNYCRNPDG 265
EC NG YRG + T +G+ C WD H + + + G N+CRNPDG
Sbjct: 35 ECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNPDG 94
Query: 266 QPRPWCYTLDPH--TRWEYCAIKTC 288
+PWCY + W YC I +C
Sbjct: 95 DVQPWCYVAETEEGIYWRYCDIPSC 119
Score = 42.4 bits (98), Expect = 5e-04
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
Query: 125 IRNCIIGKGRSYKGTVSITK---SGIKCQPWSSMIPHEHSFLPSSYRGKDL-QENYCRNP 180
+ C G Y+G + T +G C W H +S + L N+CRNP
Sbjct: 33 LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNP 92
Query: 181 RGEEGGPWCFTSNPE--VRYEVCDIPQC 206
G+ PWC+ + E + + CDIP C
Sbjct: 93 DGDV-QPWCYVAETEEGIYWRYCDIPSC 119
>gi|27437008 kringle-containing transmembrane protein 2 isoform d
precursor [Homo sapiens]
Length = 462
Score = 61.2 bits (147), Expect = 1e-09
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 210 ECMTCNGESYRGLMDHTE---SGKICQRWDHQTPHRHKFLPERYPDKGFD-DNYCRNPDG 265
EC NG YRG + T +G+ C WD H + + + G N+CRNPDG
Sbjct: 35 ECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNPDG 94
Query: 266 QPRPWCYTLDPH--TRWEYCAIKTC 288
+PWCY + W YC I +C
Sbjct: 95 DVQPWCYVAETEEGIYWRYCDIPSC 119
Score = 42.4 bits (98), Expect = 5e-04
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
Query: 125 IRNCIIGKGRSYKGTVSITK---SGIKCQPWSSMIPHEHSFLPSSYRGKDL-QENYCRNP 180
+ C G Y+G + T +G C W H +S + L N+CRNP
Sbjct: 33 LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNP 92
Query: 181 RGEEGGPWCFTSNPE--VRYEVCDIPQC 206
G+ PWC+ + E + + CDIP C
Sbjct: 93 DGDV-QPWCYVAETEEGIYWRYCDIPSC 119
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 58.5 bits (140), Expect = 7e-09
Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 6/85 (7%)
Query: 211 CMTCNGESYRGLMDHTESGKICQRWD----HQTPHRHKFLPERYPDKGFDDNYCRNPDGQ 266
C NG YRG+ + SG C W+ +Q H G YCRNPD
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLG-PHAYCRNPDND 344
Query: 267 PRPWCYTL-DPHTRWEYCAIKTCET 290
RPWCY + D WEYC ++ CE+
Sbjct: 345 ERPWCYVVKDSALSWEYCRLEACES 369
Score = 49.3 bits (116), Expect = 4e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDL---QENYCRNPRGEE 184
C +G G Y+G S + SG+ C W+S + ++ + S L YCRNP +E
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
Query: 185 GGPWCF-TSNPEVRYEVCDIPQCSEV 209
PWC+ + + +E C + C +
Sbjct: 346 -RPWCYVVKDSALSWEYCRLEACESL 370
>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
Length = 560
Score = 56.6 bits (135), Expect = 2e-08
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 210 ECMTCNGESYRGLMDHTESGKICQRWDHQT---PHRHKFLPERYPDKGFDDNYCRNPDGQ 266
+C +G SYRG M+ T + C W+ + + F+ + + N+CRNPD
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 267 PRPWCY--TLDPHTRWEYCAIKTC 288
+PWC+ + +WEYC + C
Sbjct: 253 EKPWCFIKVTNDKVKWEYCDVSAC 276
Score = 55.1 bits (131), Expect = 7e-08
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 6/86 (6%)
Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMI---PHEHSFLPSSYRGKDLQENYCRNPRGE 183
+C +G G SY+G ++ T + C W+S + + + F+ + + N+CRNP +
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252
Query: 184 EGGPWCF--TSNPEVRYEVCDIPQCS 207
E PWCF +N +V++E CD+ CS
Sbjct: 253 E-KPWCFIKVTNDKVKWEYCDVSACS 277
>gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo
sapiens]
Length = 299
Score = 50.1 bits (118), Expect = 2e-06
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 9/62 (14%)
Query: 176 YCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHT 226
YCRNP G+ GPWC+ NP ++ CDIP C+ +VE C G + H
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPRSIVGGCVAHP 66
Query: 227 ES 228
S
Sbjct: 67 HS 68
Score = 42.4 bits (98), Expect = 5e-04
Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 259 YCRNPDGQPR-PWCYTLDPHTRWEYCAIKTC 288
YCRNPDG PWCY ++P ++YC I C
Sbjct: 7 YCRNPDGDINGPWCYRVNPRKLFDYCDIPLC 37
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 46.2 bits (108), Expect = 3e-05
Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Query: 211 CMTCNGESYRGLMDHTESGKICQRWD-----HQTPHRHKFLPERYPDKGFDDNYCRNPDG 265
C NG YRG G+ C W+ QT H H+ + NYCRNPD
Sbjct: 53 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHR--SDALQLGLGKHNYCRNPDN 110
Query: 266 QPRPWCY 272
+ RPWCY
Sbjct: 111 RRRPWCY 117
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 8/73 (10%)
Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQ-----ENYC 177
D + C G G Y+G S G C PW+S + ++ ++R LQ NYC
Sbjct: 48 DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTY--HAHRSDALQLGLGKHNYC 105
Query: 178 RNPRGEEGGPWCF 190
RNP PWC+
Sbjct: 106 RNPDNRR-RPWCY 117
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 46.2 bits (108), Expect = 3e-05
Identities = 25/67 (37%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Query: 211 CMTCNGESYRGLMDHTESGKICQRWD-----HQTPHRHKFLPERYPDKGFDDNYCRNPDG 265
C NG YRG G+ C W+ QT H H+ + NYCRNPD
Sbjct: 70 CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHR--SDALQLGLGKHNYCRNPDN 127
Query: 266 QPRPWCY 272
+ RPWCY
Sbjct: 128 RRRPWCY 134
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 8/73 (10%)
Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQ-----ENYC 177
D + C G G Y+G S G C PW+S + ++ ++R LQ NYC
Sbjct: 65 DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTY--HAHRSDALQLGLGKHNYC 122
Query: 178 RNPRGEEGGPWCF 190
RNP PWC+
Sbjct: 123 RNPDNRR-RPWCY 134
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 46.2 bits (108), Expect = 3e-05
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 226 TESGKICQRWDHQTPHRHKFLPERYPD-KGFDDNYCRNPDGQPRPWCYTLDPHTR--WEY 282
T+ G C RW P + P + +G N+CR+PDG RPWC+ D + W Y
Sbjct: 103 TDFGAPCLRWAEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGY 162
Query: 283 C 283
C
Sbjct: 163 C 163
Score = 39.3 bits (90), Expect = 0.004
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 140 VSITKSGIKCQPWSSMIPHEHSFLPSSY---RGKDLQENYCRNPRGEEGGPWCF--TSNP 194
VS+T G C W+ + P P+S+ RG+ + N+CR+P G G PWCF +
Sbjct: 100 VSVTDFGAPCLRWAEVPPFLERSPPASWAQLRGQ--RHNFCRSPDG-AGRPWCFYGDARG 156
Query: 195 EVRYEVCD 202
+V + CD
Sbjct: 157 KVDWGYCD 164
>gi|209571507 HGFL protein isoform 2 [Homo sapiens]
Length = 173
Score = 37.7 bits (86), Expect = 0.012
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C G Y+ + G++C W S L S+ +YCRNP + GP
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDA----QSGLASAPVSGAGNHSYCRNPDEDPRGP 80
Query: 188 WCFTSN----PEVRYEVCDIPQCSE 208
WC+ S PE R C+ +C E
Sbjct: 81 WCYVSGEAGVPEKR--PCEDLRCPE 103
Score = 35.0 bits (79), Expect = 0.077
Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 7/64 (10%)
Query: 211 CMTCNGESYRGLMDHTESGKICQRW-DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 268
C NG YR G C W D Q+ L + +YCRNPD PR
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDAQSG-----LASAPVSGAGNHSYCRNPDEDPRG 79
Query: 269 PWCY 272
PWCY
Sbjct: 80 PWCY 83
>gi|51317358 HGFL protein isoform 1 [Homo sapiens]
Length = 263
Score = 37.7 bits (86), Expect = 0.012
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)
Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
C G Y+ + G++C W S L S+ +YCRNP + GP
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDA----QSGLASAPVSGAGNHSYCRNPDEDPRGP 80
Query: 188 WCFTSN----PEVRYEVCDIPQCSE 208
WC+ S PE R C+ +C E
Sbjct: 81 WCYVSGEAGVPEKR--PCEDLRCPE 103
Score = 35.0 bits (79), Expect = 0.077
Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 7/64 (10%)
Query: 211 CMTCNGESYRGLMDHTESGKICQRW-DHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPR- 268
C NG YR G C W D Q+ L + +YCRNPD PR
Sbjct: 25 CFWDNGHLYREDQTSPAPGLRCLNWLDAQSG-----LASAPVSGAGNHSYCRNPDEDPRG 79
Query: 269 PWCY 272
PWCY
Sbjct: 80 PWCY 83
>gi|40806187 ADAM metallopeptidase with thrombospondin type 1 motif,
18 preproprotein [Homo sapiens]
Length = 1221
Score = 35.4 bits (80), Expect = 0.059
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 9/60 (15%)
Query: 169 GKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE-------VECMTCNGESYRG 221
G QE +C NP+ + GG +C S+ Y++C+I C+E +C N + +RG
Sbjct: 608 GVKFQERHCNNPKPQYGGLFCPGSSR--IYQLCNINPCNENSLDFRAQQCAEYNSKPFRG 665
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,221,049
Number of Sequences: 37866
Number of extensions: 672819
Number of successful extensions: 1375
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1166
Number of HSP's gapped (non-prelim): 103
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.