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Search of human proteins with 58331218
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58331218 arsenate resistance protein 2 isoform a [Homo
sapiens]
(876 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 1818 0.0
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] 1811 0.0
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 1801 0.0
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] 1795 0.0
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 79 2e-14
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 70 1e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 67 6e-11
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 66 2e-10
gi|83921609 hypothetical protein LOC127254 [Homo sapiens] 65 3e-10
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 64 5e-10
gi|55741677 SET domain containing 1A [Homo sapiens] 64 8e-10
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 63 1e-09
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 62 2e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 62 3e-09
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 62 3e-09
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 60 7e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 60 9e-09
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 59 2e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 59 3e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 58 3e-08
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 58 3e-08
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 58 3e-08
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 58 3e-08
gi|4557509 cylicin 2 [Homo sapiens] 57 6e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 57 7e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 7e-08
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 57 7e-08
gi|55956788 nucleolin [Homo sapiens] 57 1e-07
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 57 1e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 56 1e-07
>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
Length = 876
Score = 1818 bits (4709), Expect = 0.0
Identities = 876/876 (100%), Positives = 876/876 (100%)
Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 780
KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG
Sbjct: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 780
Query: 781 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 840
LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR
Sbjct: 781 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 840
Query: 841 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 876
GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 841 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 876
>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
Length = 875
Score = 1811 bits (4692), Expect = 0.0
Identities = 875/876 (99%), Positives = 875/876 (99%), Gaps = 1/876 (0%)
Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
SFDEGSVSESESESESGQAEEEKEEAE ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAE-ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 419
Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 420 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 479
Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 480 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 539
Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 540 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 599
Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 600 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 659
Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 660 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 719
Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 780
KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG
Sbjct: 720 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 779
Query: 781 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 840
LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR
Sbjct: 780 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 839
Query: 841 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 876
GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 840 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 875
>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
Length = 872
Score = 1801 bits (4666), Expect = 0.0
Identities = 871/876 (99%), Positives = 871/876 (99%), Gaps = 4/876 (0%)
Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 780
KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ
Sbjct: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ----S 776
Query: 781 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 840
LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR
Sbjct: 777 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 836
Query: 841 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 876
GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 837 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 872
>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
Length = 871
Score = 1795 bits (4649), Expect = 0.0
Identities = 870/876 (99%), Positives = 870/876 (99%), Gaps = 5/876 (0%)
Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR
Sbjct: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV
Sbjct: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR
Sbjct: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI
Sbjct: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER
Sbjct: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD
Sbjct: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 420
SFDEGSVSESESESESGQAEEEKEEAE ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT
Sbjct: 361 SFDEGSVSESESESESGQAEEEKEEAE-ALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT 419
Query: 421 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 480
CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW
Sbjct: 420 CSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICW 479
Query: 481 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 540
NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS
Sbjct: 480 NLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWAS 539
Query: 541 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 600
EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE
Sbjct: 540 EPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVE 599
Query: 601 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 660
RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL
Sbjct: 600 RDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVL 659
Query: 661 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 720
EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK
Sbjct: 660 EWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGK 719
Query: 721 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQILPPG 780
KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ
Sbjct: 720 KFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQ----S 775
Query: 781 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 840
LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR
Sbjct: 776 LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFR 835
Query: 841 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 876
GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
Sbjct: 836 GQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF 871
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 79.0 bits (193), Expect = 2e-14
Identities = 50/142 (35%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE---KKEDGKQAENDSSN-DDK 324
++E+EE+Q + GE K+++ G G ++ N+K E +KEDGK+ E+ N +D
Sbjct: 130 QKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDG 189
Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
+K E + ++E++KE + + + K++ K G D V E E E E G+ E+E
Sbjct: 190 KEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDV----KVKEDEKEREDGK-EDEGG 244
Query: 385 EAEEALKEKEKPKEEEWEKPKD 406
EEA KEKE KEEE K +D
Sbjct: 245 NEEEAGKEKEDLKEEEEGKEED 266
Score = 65.1 bits (157), Expect = 3e-10
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 18/162 (11%)
Query: 252 AAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-GAGLGDGERKTNDKDEKK- 309
AA +K E + + ++E++ E+ G+ G+ K E+G G +G K D EK+
Sbjct: 120 AAEVKNEEEDQKE----DEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED 175
Query: 310 -----------EDGKQA-ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS 357
EDGK+ E++ +D+ + +G +++ K++ +KE K K + K
Sbjct: 176 GKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKER 235
Query: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
D DEG E + + EEE+ + E+ +KE + KEE
Sbjct: 236 EDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
Score = 53.5 bits (127), Expect = 8e-07
Identities = 44/175 (25%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Query: 243 ADAIVKMLDAAVIKM---EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE 299
A A+ + AV++ E + +I E E++ + KEE A GE
Sbjct: 60 AQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEV-----KEENIEDATEKGGE 114
Query: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKK-RNRKHSG 358
+K E K + + + D + ++ K G DK+EK E+ KE K ++K + K
Sbjct: 115 KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKE 174
Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
D E E E G+ E+E+E+ +E KE +E K+ ++ K
Sbjct: 175 DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVK 229
Score = 43.5 bits (101), Expect = 9e-04
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAE 316
+G E+ E E+EEE + G+ + E+G+ +G+ +DEK +EDGK+ E
Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242
Query: 317 NDSSND------DKTKKSEGDGDKEEKKEDSEKEAKKS 348
+ + D ++ EG + E K++D +KE +S
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280
Score = 31.6 bits (70), Expect = 3.4
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
K EG D+++ E E+E E + +++E G+ L + E + + K++DGK+
Sbjct: 220 KKEG---KDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKE 276
Query: 316 ENDS 319
E S
Sbjct: 277 EPQS 280
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 69.7 bits (169), Expect = 1e-11
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 10/155 (6%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE------- 310
EG E + E E EEE+ GE + EG G G+GE + + E++E
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923
Query: 311 DGKQAENDSSNDD---KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV 367
+G++ E + ++ + + EG+G++EE + + E+E + + + G++ EG
Sbjct: 924 EGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE 983
Query: 368 SESESESESGQAEEEKEEAEEALKEKEKPKEEEWE 402
E E E E + EEE EE E +E E EEE E
Sbjct: 984 EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Score = 68.9 bits (167), Expect = 2e-11
Identities = 45/156 (28%), Positives = 79/156 (50%), Gaps = 14/156 (8%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK---- 313
EG E + + EEEE GK E ++ EG G+GE + + + ++E+G+
Sbjct: 899 EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958
Query: 314 ----QAENDSSNDDKTKKSEGDGDKEE-----KKEDSEKEAKKSSKKRNRKHSGDDSFDE 364
+ E + + + ++ EG+G++EE ++E+ E+E ++ + + +E
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Query: 365 GSVSESESESESGQAEEEKEEAEEALKEKEKPKEEE 400
G V E E E E G+ E E+EE EE +E+EK E E
Sbjct: 1019 GEV-EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE 1053
Score = 68.2 bits (165), Expect = 3e-11
Identities = 46/164 (28%), Positives = 84/164 (51%), Gaps = 8/164 (4%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGE-PSKKEEGRA----GAGLGDGERKTNDKDEKKE 310
++EGG + + +EEEEE G+ E ++EEG G G G+ E + + +E+ E
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Query: 311 DGK-QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS- 368
+G+ + E + + ++ EG+G++EE + + E+E + ++ + G++ +EG
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932
Query: 369 -ESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
E E E E E E EE E + +E+ E E E+ + G E
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976
Score = 68.2 bits (165), Expect = 3e-11
Identities = 40/137 (29%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329
+EEE E + GE +EEG G G +GE + +E++ +G + E + + + ++ E
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG-EGEEEGEGEGEEEEGE 901
Query: 330 GDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS----ESESESESGQAEEEKEE 385
G+G++E + E E+E + ++ + G+ +EG E E E E G+ E E+EE
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Query: 386 AEEALKEKEKPKEEEWE 402
E +E+ + + EE E
Sbjct: 962 GEGEGEEEGEGEGEEGE 978
Score = 66.6 bits (161), Expect = 9e-11
Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 10/145 (6%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
K EGG E E E + GK ++EEG G+GE + + +E++ +GK
Sbjct: 808 KEEGG--------EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE 859
Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
E + + + EG+G+ EE E+ E E ++ + + G+ +E E E E
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEE--EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 376 SGQAEEEKEEAEEALKEKEKPKEEE 400
G+ EEE EE E +E+E E E
Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGEGE 942
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/174 (29%), Positives = 82/174 (47%), Gaps = 15/174 (8%)
Query: 255 IKMEGGTENDLRILEQE---EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDE-KKE 310
+K+ GG + IL + + E GK + E+G G G G E ++ + + E
Sbjct: 613 VKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDE 672
Query: 311 DGKQAENDSSNDDKTKKSEGD---GDKEE-KKEDSEKEAKKS-----SKKRNRK--HSGD 359
+ ++ E D + + EG+ +KEE KK D E++ +K K+RN++ G+
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE 732
Query: 360 DSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
+ EG E + E E + E KEE E E E+ KEE K ++ AG E K
Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786
Score = 64.7 bits (156), Expect = 4e-10
Identities = 39/163 (23%), Positives = 83/163 (50%), Gaps = 10/163 (6%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA---GAGLGDGERKTNDKDEKKEDG 312
+ME E + + E+EE +++ G+ E ++E+G + +G + + + E++E
Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744
Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372
++ E + + K EG+G++ E + + E+ +K ++ ++ G++ D+G E E+
Sbjct: 745 REEEEEKEGEGK---EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEET 801
Query: 373 ESESGQAEEEKE----EAEEALKEKEKPKEEEWEKPKDAAGLE 411
E + EE E E EE E+E+ +EE + ++ G E
Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE 844
Score = 64.7 bits (156), Expect = 4e-10
Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
+ME G E + E+EE + + + E KEEG G+ E++ ++ +++ GK+
Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Query: 316 ENDSSNDD-KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374
+ + D + ++ E +G EEK+E E E + + + + ++ EG E E E
Sbjct: 786 KGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEE-GEGEEEEGEGEE 844
Query: 375 ESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
E G+ EEE+ E + + +E EEE E+
Sbjct: 845 EEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Score = 64.3 bits (155), Expect = 5e-10
Identities = 42/148 (28%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE---DGKQAENDSSNDDKT 325
EQE++E + G E +++ E G+GE + D++E++E +GK+ + +
Sbjct: 709 EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER 768
Query: 326 KKSEGDGDKEE---KKEDSEKEAKKSS-KKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
+K EG+ KEE K+E E+E + ++ + G++ + G V E E G+ EE
Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828
Query: 382 EKEEAEEALKEKEKPKEEEWEKPKDAAG 409
E+EE E +E E +EE + ++ G
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEG 856
Score = 64.3 bits (155), Expect = 5e-10
Identities = 47/158 (29%), Positives = 80/158 (50%), Gaps = 28/158 (17%)
Query: 269 EQEEEE-----EQAGKPGEPSKKEE---GRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
E EEEE E+ G+ GE +EE G G G+GE + + + ++E+G + E +
Sbjct: 911 EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG-EGEGEEE 969
Query: 321 NDDKTKKSEGDGDKEE-----KKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
+ + ++ EG+G++EE ++E+ E+E ++ + + +EG V E E E E
Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV-EGEVEGE 1028
Query: 376 SGQAEEEKEEAEEALKEKEK-------------PKEEE 400
G+ E E+EE EE +E+EK +EEE
Sbjct: 1029 EGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Score = 63.9 bits (154), Expect = 6e-10
Identities = 40/144 (27%), Positives = 70/144 (48%), Gaps = 10/144 (6%)
Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGER------KTNDKDEKKEDGKQAENDSSNDD 323
+EE EE G+ E + EG G G G+ E + + E +E+G+ + +
Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981
Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS----ESESESESGQA 379
+ ++ EG+G++EE +E+ E+E + + ++ EG V E E E E G+
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041
Query: 380 EEEKEEAEEALKEKEKPKEEEWEK 403
E E+ E E +E + +EEE E+
Sbjct: 1042 EGEEREKEGEGEENRRNREEEEEE 1065
Score = 63.5 bits (153), Expect = 8e-10
Identities = 40/143 (27%), Positives = 74/143 (51%), Gaps = 3/143 (2%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERK-TNDKDEKKEDGKQAENDSSNDDKTKK 327
E+E+EE + K K+E+G G+GE + T + E+KE+G + E + K ++
Sbjct: 767 EREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826
Query: 328 SEGDGDKEEKKEDSEKEAKKSS-KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
E + + E ++E+ E E ++ ++ + G++ +EG E E E G+ EEE+ E
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE-GEEEGEEGEGEGEEEEGEG 885
Query: 387 EEALKEKEKPKEEEWEKPKDAAG 409
E + + + +EEE E + G
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEG 908
Score = 62.0 bits (149), Expect = 2e-09
Identities = 41/152 (26%), Positives = 75/152 (49%), Gaps = 11/152 (7%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
E+E E E + GE +EEG G G G+ E + ++ + +G++ E + +++ +
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE--EG 962
Query: 329 EGDGDKEEKKEDSEKEA---KKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
EG+G++E + E E E ++ + + G++ +E E E E E + EE + E
Sbjct: 963 EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022
Query: 386 AE------EALKEKEKPKEEEWEKPKDAAGLE 411
E E E+E+ +EE E+ K+ G E
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEE 1054
Score = 61.6 bits (148), Expect = 3e-09
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 21/173 (12%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSK-KEEGRAGAGLGD-----GERKTNDKDEKKED 311
EG E + E+EE E + + GE + +EEG G G G+ GE + + E +E+
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898
Query: 312 GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKK------------SSKKRNRKHSGD 359
+ E + + + ++ EG+G EE+ E+ E E ++ ++ + G+
Sbjct: 899 EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE 958
Query: 360 DSFDEG---SVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
+ EG E E E G+ EEE+ E E +E E+ EEE E ++ G
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Score = 61.6 bits (148), Expect = 3e-09
Identities = 37/129 (28%), Positives = 70/129 (54%), Gaps = 12/129 (9%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGK-----QAENDSSND 322
E EEE E G+ GE +EE G G + GE + ++ E +E+G+ + E + +
Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024
Query: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
+ ++ EG+G++EE +E+ E+ K+ + NR++ ++ +EG E+G+ E E
Sbjct: 1025 VEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY------QETGEEENE 1078
Query: 383 KEEAEEALK 391
+++ EE K
Sbjct: 1079 RQDGEEYKK 1087
Score = 61.2 bits (147), Expect = 4e-09
Identities = 54/247 (21%), Positives = 108/247 (43%), Gaps = 5/247 (2%)
Query: 165 ETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVF 224
E E ++ K D Q+ ++ H+ E + +E +E G +
Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752
Query: 225 LSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPS 284
E G + + + +K + K + A + +G E D E+EE E + + E
Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812
Query: 285 KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKE 344
+ E G G G+ E + + + ++E+G+ E + +++ + EG G++E ++ + E+E
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE--EGEGKGEEEGEEGEGEEE 870
Query: 345 AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKP 404
++ + + + +EG E E E E G+ E E+E E +E+ + K EE +
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEG---EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927
Query: 405 KDAAGLE 411
+ G E
Sbjct: 928 GEGEGEE 934
Score = 61.2 bits (147), Expect = 4e-09
Identities = 43/158 (27%), Positives = 76/158 (48%), Gaps = 15/158 (9%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
EG E + E EEEE + GE ++ EG G G+GE + + + ++E+G++
Sbjct: 945 EGEGEEEEGEWEGEEEEGE----GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
+ ++ EG+G+ EE+ E+ E E + ++ + ++ +EG E E E E
Sbjct: 1001 EEGEGEE----EGEGEGEEE-EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055
Query: 378 QAEEEKEEAEEAL------KEKEKPKEEEWEKPKDAAG 409
+ E+EE EE +E E+ EE++K G
Sbjct: 1056 RRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKG 1093
Score = 55.5 bits (132), Expect = 2e-07
Identities = 49/190 (25%), Positives = 85/190 (44%), Gaps = 27/190 (14%)
Query: 242 KADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGL-GDGER 300
KA ++ + D + +G E E ++EE+ E +K++GR G+GE+
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEER-----EKGEKDKGRGEMERPGEGEK 694
Query: 301 KTNDKDE-KKEDGKQAENDSSNDDKTKK---------SEGDGDKEEKKEDSEKEAKKSSK 350
+ +K+E KK DG++ E K+ E G+ EE++ D E+E +K +
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754
Query: 351 KR-----------NRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
+ K G+ +E + E + E E Q E E+EE E +EKE+ E
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814
Query: 400 EWEKPKDAAG 409
E + ++ G
Sbjct: 815 EGGEVEEGKG 824
Score = 50.8 bits (120), Expect = 5e-06
Identities = 33/136 (24%), Positives = 69/136 (50%), Gaps = 9/136 (6%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK-- 326
E EEEEE GE + EG G G G+ E + +E++++G+ EN + +++ +
Sbjct: 1012 EGEEEEE-----GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 327 -KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
K + G++E +++D E+ K S K + K+ ++ + SV+ ++ + Q + +
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKE-QRSKMPVQ 1125
Query: 386 AEEALKEKEKPKEEEW 401
++ LK ++ W
Sbjct: 1126 SKRLLKNGPSGSKKFW 1141
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 16/139 (11%)
Query: 283 PSKKE--EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKED 340
P +KE E G G+ + E + N+++ K G++ + + +DD T K+E E K
Sbjct: 587 PEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAE----VSEGKAK 642
Query: 341 SEKEAKKSSKKRNRKHSGDDSFDEGSVSES---ESESESGQAEEEKEEAEEALK-EKEKP 396
S EA+ + R GD + +EGS + E E G+ ++ + E E + EKE
Sbjct: 643 SVGEAEDGPEGR-----GDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA 697
Query: 397 KEEEWEKPKDAAGLECKPR 415
++EEW+K +D E K R
Sbjct: 698 EKEEWKK-RDGEEQEQKER 715
Score = 38.9 bits (89), Expect = 0.021
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 15/163 (9%)
Query: 259 GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-----GAGLGDGERKTNDKDEKKEDGK 313
G D + E ++ +E E S+ +EG+A G+ + T + E+ +
Sbjct: 530 GELTQDTALTENDDSDEYE----EMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVE 585
Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAK-KSSKKRNRKHSGDDSFDEGSVSESES 372
E +D S+G+G +E++ E +E+ K +K + DD D+ VSE ++
Sbjct: 586 IPEEKEGAED----SKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKA 641
Query: 373 ESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
+S G+AE+ E + E+ E W+ + G + K R
Sbjct: 642 KS-VGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGR 683
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 67.4 bits (163), Expect = 6e-11
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 14/155 (9%)
Query: 259 GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEND 318
GG E++ L +E+E + + E ++EE D + ++D+DE + D + D
Sbjct: 1032 GGEEDEKESLSEEQESTEEEEEAEEEEEEED-------DDDDDSDDRDESEND----DED 1080
Query: 319 SSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
++ + ++K EGD D+EE +A+ +S + + S +S E S S SE E E
Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVA 1140
Query: 379 AEEEKEEAEEALKEKEKPKE---EEWEKPKDAAGL 410
EEE+EE EE + +E E++E+ + A L
Sbjct: 1141 REEEEEEEEEEMVAEESMASAGPEDFEQDGEEAAL 1175
Score = 48.9 bits (115), Expect = 2e-05
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 27/170 (15%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLG-------DGERKTNDKDEKKEDGKQAENDSSN 321
E+E + + A P E +K++ G D + ++K+ E+ + E +
Sbjct: 995 ERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEA 1054
Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSV-------------- 367
+++ ++ + D D + +++SE + + ++ + DS +E +V
Sbjct: 1055 EEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSE 1114
Query: 368 ----SESESESESGQAEEEKEEAEEALKEKEKPKEEEW--EKPKDAAGLE 411
SE ES SES + E EE A +E+E+ +EEE E+ +AG E
Sbjct: 1115 SSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPE 1164
Score = 38.5 bits (88), Expect = 0.028
Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 14/125 (11%)
Query: 289 GRAGAGLGDGERKT----NDKDEKKE--------DGKQAENDSSNDDKTKKSEGDGDKEE 336
G G GLG G R + K ++KE D K+ +S D++ ++SE + D++
Sbjct: 943 GYEGLGLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDM 1002
Query: 337 KKEDSE--KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
E K K R R + G E ES SE ++ EE+EEAEE +E++
Sbjct: 1003 ADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEED 1062
Query: 395 KPKEE 399
++
Sbjct: 1063 DDDDD 1067
Score = 33.9 bits (76), Expect = 0.68
Identities = 23/68 (33%), Positives = 27/68 (39%), Gaps = 5/68 (7%)
Query: 760 PALPEIKPAQPPGPAQILPPG--LTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAV 817
P P + P PP P Q PG + P LP P P P PP L G P +
Sbjct: 685 PGFPPLPPPPPPPPPQ---PGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPI 741
Query: 818 PTGGPPYP 825
PP+P
Sbjct: 742 LPPLPPFP 749
Score = 32.7 bits (73), Expect = 1.5
Identities = 24/69 (34%), Positives = 24/69 (34%), Gaps = 16/69 (23%)
Query: 760 PALPEIKPAQPPGPAQILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPT 819
P P P PP P PP PG P P P P P PP PAV
Sbjct: 682 PPPPGFPPLPPPPP----PPPPQPGFPMPPPLP----PPPPPPPP--------AHPAVTV 725
Query: 820 GGPPYPHAP 828
PP P P
Sbjct: 726 PPPPLPAPP 734
Score = 31.2 bits (69), Expect = 4.4
Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 9/81 (11%)
Query: 754 LTDAKRPALPEIKPAQP------PGPAQILPPG-LTPGLPYPHQTPQGLMPYGQPRPPIL 806
++D + P+ P P PG A + P L P LP P P G P P PP
Sbjct: 641 ISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP--PPPGFPPLPPPPPPPP 698
Query: 807 GYGAGAVRPAVPTGGPPYPHA 827
+ P +P PP P A
Sbjct: 699 PQPGFPMPPPLPPPPPPPPPA 719
Score = 30.4 bits (67), Expect = 7.5
Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 11/81 (13%)
Query: 756 DAKRPALPEIKPAQP----PGPAQILPPGLTPGLPYPHQTPQGLMPYGQPRPPILGYGAG 811
+A+ P PE P P P +LP L P LP P P P PP
Sbjct: 1249 EARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPR-------PPRPPSPPPEPETTD 1301
Query: 812 AVRPAVPTGGPPYPHAPYGAG 832
A P+VP H P+ G
Sbjct: 1302 ASHPSVPPEPLAEDHPPHTPG 1322
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 65.9 bits (159), Expect = 2e-10
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 10/152 (6%)
Query: 259 GGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAG-----LGDGERKTNDKDEKKEDGK 313
GG E+ + E E E G+ GE + + E +G G+GE +T K E+ ED
Sbjct: 742 GGQED---VAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDEN 798
Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSF--DEGSVSESE 371
+AE N+ + + D E K + E E+++ S + + + D+ D G +
Sbjct: 799 EAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGD 858
Query: 372 SESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
SE E + EE++EE EE +E+E+ +EEE E+
Sbjct: 859 SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890
Score = 41.6 bits (96), Expect = 0.003
Identities = 48/210 (22%), Positives = 82/210 (39%), Gaps = 63/210 (30%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGR--------------AGAGLGD--GERKTNDKDEKKEDG 312
E+EEE G +P K E + A + D G++K N + ED
Sbjct: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQ--EDV 747
Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKK------------------EDSEKEAKKSSKKRNR 354
+AE+ + ++ G+G+ EEK E+ E E + K N
Sbjct: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807
Query: 355 -KHSGDDSFDEGSVSESESESES--------------------------GQAEEEKEEAE 387
+ G+ ++G + +E E+ES G +EEE+EE E
Sbjct: 808 GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867
Query: 388 EALKEKEKPKEEEWEKPKDAAGLECKPRPL 417
E +E+E+ ++EE E+ ++ + PL
Sbjct: 868 EQEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897
>gi|83921609 hypothetical protein LOC127254 [Homo sapiens]
Length = 1530
Score = 65.1 bits (157), Expect = 3e-10
Identities = 48/180 (26%), Positives = 85/180 (47%), Gaps = 17/180 (9%)
Query: 257 MEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGL-GDGERKTNDKDEKKEDGKQA 315
+E EN L+ +E+ E K GE S EEG+A + G + +DK + + K++
Sbjct: 486 LEDDQENTLKYEYEEDFEVDEEKQGEKSN-EEGQADVQMNGIPQSPLDDKKDNLDPEKES 544
Query: 316 ENDSSNDDKTK---KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS-GDDSFDEGSVSESE 371
E S + K E DG E + E+ +++ K +S +R H DS DE +V + E
Sbjct: 545 ETSSQKAPDARDNVKDENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDRE 604
Query: 372 SESESGQAEEEKEEAEEALKEKEKPKE-----------EEWEKPKDAAGLECKPRPLHKT 420
+ ++S E + + + L E +KP++ E ++ A +E KP P+ ++
Sbjct: 605 AHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKADVETKPMPIDES 664
Score = 37.0 bits (84), Expect = 0.080
Identities = 51/210 (24%), Positives = 78/210 (37%), Gaps = 44/210 (20%)
Query: 247 VKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEP--------SKKEEGRAGAGLGDG 298
V L A EG E + + + E EE+A E SK+E+G A LG G
Sbjct: 919 VAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILG-G 977
Query: 299 ERKTNDKDE--------------------KKEDGKQAENDSSNDDKTKKSEGDGDK---- 334
E ++ E + +G E + + K + +G++
Sbjct: 978 EEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDVEGEEMVTE 1037
Query: 335 -EEKKEDSEKE--------AKKSSKKRNRKHS--GDDSFDEGSVSESESESESGQAEEEK 383
E +ED KE A++ K K S DS E + + E EE+K
Sbjct: 1038 AEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQK 1097
Query: 384 EEAEEALKEKEKPKEEEWEKPKDAAGLECK 413
+AEE E E EEE + P + G + +
Sbjct: 1098 LKAEEGETETEVRAEEETKAPPNEMGSDAE 1127
Score = 34.7 bits (78), Expect = 0.40
Identities = 31/147 (21%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
+G +E++L +Q+ + + + + +GD E T D + + +
Sbjct: 563 DGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHT-DSSTDESARRSSSQ 621
Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES-ES 376
+ S +DK +KS ++ + E ++E K+ + + D+SF+ +E + E
Sbjct: 622 ELSENDKPRKSHLPIEESLEIEIEDQEITKADVE-TKPMPIDESFENVLKEGTEKGTQEI 680
Query: 377 GQAEEEKEEAEEALKEKEKPKEEEWEK 403
+ EK + +EKEK K + WE+
Sbjct: 681 AEGLSEKSGKHVSAEEKEKDKSKLWEE 707
Score = 34.7 bits (78), Expect = 0.40
Identities = 26/110 (23%), Positives = 49/110 (44%), Gaps = 9/110 (8%)
Query: 304 DKDEKKEDGKQA--ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK--HSGD 359
D+D ++E+ K+ E ++ D + SEGDGD E + + E + + H G
Sbjct: 1291 DEDPEEEEDKECTLETEAMQD---RNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGG 1347
Query: 360 DSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
++ + + +E + EEK A +A + +EE W + + G
Sbjct: 1348 ETAE--TAAEEREVLAGSETAEEKTIANKASSFSDVAEEETWHQQDELVG 1395
Score = 32.3 bits (72), Expect = 2.0
Identities = 42/187 (22%), Positives = 72/187 (38%), Gaps = 22/187 (11%)
Query: 241 DKADAIVKMLDAAVIKMEGGT-ENDLRILEQEEEEEQAGKP--GEPSKKEEGRAGAGLGD 297
D+ + + K LD A + + + LR + E EE E + KEE + A G+
Sbjct: 1045 DRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGE 1104
Query: 298 GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEA-----------K 346
E + ++E K + +D+ N+ + SE + EDS KE +
Sbjct: 1105 TETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFE 1164
Query: 347 KSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEE------EKEEAEEALKEKEKPKE 398
KS + RK G + E +E + E E +++ E AL E
Sbjct: 1165 KSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGEGALAAPEAEPA 1224
Query: 399 EEWEKPK 405
+ + P+
Sbjct: 1225 GKVQAPE 1231
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 64.3 bits (155), Expect = 5e-10
Identities = 30/107 (28%), Positives = 60/107 (56%)
Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
+++T + +E +E ++ E + +K K+ + +K++K +++EK +K +++ RK
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPK 405
+E E E E E + EEEKEE K+K++ ++EE E+ K
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Score = 54.3 bits (129), Expect = 5e-07
Identities = 34/111 (30%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 305 KDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAK-KSSKKRNRKHSGDDSFD 363
K +KKE + E + + +++ K+ + ++EK+++ EK+ K K ++KR K +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 364 EGSVSESESESESGQAEEEKEEAEEALKE---------KEKPKEEEWEKPK 405
+ E E + EEE+EE EE KE K + KEEE EK K
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 47.4 bits (111), Expect = 6e-05
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSK---KRNRKHSGDDSFDEGSVSESESESESGQAE 380
K K++E + EE +E+ EKE K+ K KR K + + E E E + + +
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65
Query: 381 EEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
+K++ EE +E+E+ +EEE E+ + G K +
Sbjct: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100
Score = 47.0 bits (110), Expect = 8e-05
Identities = 23/83 (27%), Positives = 44/83 (53%)
Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
K KK + + EE +E E+E K+ +K RK + + E+E E + E+++
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 384 EEAEEALKEKEKPKEEEWEKPKD 406
+ + KE+E+ +EEE E+ ++
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEE 85
Score = 36.2 bits (82), Expect = 0.14
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 7/63 (11%)
Query: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK-------EKEKPKEEEWE 402
KK+ +K + +E +E E E E + E+ KE+ +E K EK K KEEE +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 403 KPK 405
K K
Sbjct: 61 KRK 63
Score = 33.5 bits (75), Expect = 0.89
Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 346 KKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE-EAEEALKEKEKPKEEEWEKP 404
KK KK+ +++ + E E + + + E+ KE E ++ KE EK KE+E E+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 405 K 405
K
Sbjct: 61 K 61
Score = 32.3 bits (72), Expect = 2.0
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 336 EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEK 395
+KK+ +KE +++ + + +E E E + +E+K++ +E K KEK
Sbjct: 1 KKKKKKKKETEETEETEETEEE-----EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55
Query: 396 PKEEEWEKPK 405
+EE+ K K
Sbjct: 56 EEEEKKRKRK 65
Score = 31.2 bits (69), Expect = 4.4
Identities = 14/66 (21%), Positives = 33/66 (50%)
Query: 17 RRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPP 76
R+E+ + ++ R+R +++ ++ E + E E ++ R R+++ R E
Sbjct: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111
Query: 77 QKRMRR 82
+K+ RR
Sbjct: 112 KKKKRR 117
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 63.5 bits (153), Expect = 8e-10
Identities = 49/159 (30%), Positives = 73/159 (45%), Gaps = 14/159 (8%)
Query: 269 EQEEEEEQAGKPG-EPSKKEEGRAGAGLGDGE-RKTNDKDEKKEDGKQAENDSSNDDKTK 326
EQE+E + G+PG +P K++E R G G+ RK+ D + E+ Q + +++ +
Sbjct: 926 EQEKEAGEPGRPGTKPPKRDEER---GKTQGKHRKSFALDSEGEEASQESSSEKDEEDDE 982
Query: 327 KSEGDGDKEE-----KKE----DSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
+ E D D+EE KKE D E E SS K + D D S SES S S S
Sbjct: 983 EDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSS 1042
Query: 378 QAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRP 416
+ + + E E+E E+ + AA P P
Sbjct: 1043 SSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPP 1081
Score = 41.2 bits (95), Expect = 0.004
Identities = 37/165 (22%), Positives = 70/165 (42%), Gaps = 7/165 (4%)
Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK--QAENDSSNDDKTKKSEGDGDKEE 336
K G + E G+GL R + K ++KE + +A + T E + D E+
Sbjct: 868 KSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQ 927
Query: 337 KKEDSE--KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
+KE E + K K+ + + +SE E S ++ EK+E ++ E++
Sbjct: 928 EKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEED 987
Query: 395 KPKEE---EWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAE 436
+ +EE +K + + E + CSL+ + N S ++
Sbjct: 988 EDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSD 1032
Score = 37.4 bits (85), Expect = 0.061
Identities = 57/243 (23%), Positives = 83/243 (34%), Gaps = 67/243 (27%)
Query: 190 AHKDEEWFRSKYHPDEVGK------RRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKA 243
A +DE+ + E G+ +R E RG Q + R +L G ++A
Sbjct: 918 AEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEG---------EEA 968
Query: 244 DAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTN 303
+++ K E E D ++EE + T
Sbjct: 969 SQ-----ESSSEKDEEDDEEDEEDEDREEAVD--------------------------TT 997
Query: 304 DKDEKKEDGKQAENDSSND-DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSF 362
K+ + DG+ E+DSS+ S+G+ D E S + SS S
Sbjct: 998 KKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSS-----------SS 1046
Query: 363 DEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE---------EWEKPKDAAGLECK 413
S S S S SES +EE+EE AL P E E P+ AG
Sbjct: 1047 SSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVT 1106
Query: 414 PRP 416
P P
Sbjct: 1107 PLP 1109
Score = 32.7 bits (73), Expect = 1.5
Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 13/69 (18%)
Query: 760 PALPEIKPAQPPGPAQILPPGLTPGLP--YPHQTPQGLMPYGQPRPPILGYGAGAVRPAV 817
P P+ P PP P PP LP YP P L+P PRP G P
Sbjct: 598 PTPPQQPPPPPPPPPP--PPPYLASLPLGYPPHQPAYLLP---PRPD------GPPPPEY 646
Query: 818 PTGGPPYPH 826
P PP PH
Sbjct: 647 PPPPPPPPH 655
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 62.8 bits (151), Expect = 1e-09
Identities = 41/122 (33%), Positives = 61/122 (50%), Gaps = 16/122 (13%)
Query: 299 ERKTNDKDEKKED--GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356
++K DK KK++ K+ E D D+ K GD ++KKED ++ K+ +K
Sbjct: 798 DKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRK----- 852
Query: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLE--CKP 414
DDS D + E+E ++ Q E + EAEEA E++ EEE K D + CK
Sbjct: 853 --DDSKD-----DDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905
Query: 415 RP 416
RP
Sbjct: 906 RP 907
Score = 34.3 bits (77), Expect = 0.52
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWND--REWDRGRERRSRGEYRDYDR 60
+ DDE D + K R+ D D+ +RDER++ D D ++ D E ++ EY +
Sbjct: 817 ERDDETDEPK-PKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEA 875
Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSD 90
E R E ++ +RD + + +
Sbjct: 876 EEAEDEEDDRDEEEMTKRDDKRDINRYCKE 905
Score = 30.4 bits (67), Expect = 7.5
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 4/60 (6%)
Query: 26 SRERDERRRGDDWNDREWDRGRER---RSRGEYRDYDRNRRERFSPPRHELSPPQKRMRR 82
SR RGD +R+ DR RER R R R R +R R PR E +R+RR
Sbjct: 299 SRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQR-KRSRERSPRRERERSPRRVRR 357
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 62.4 bits (150), Expect = 2e-09
Identities = 40/150 (26%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGKQAENDSSNDD- 323
+ + EEEE + S+ E G G+ GE +++D ++ + +++S +
Sbjct: 674 KFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESG 733
Query: 324 -KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
+ K++ K + K DSE K++ K + S D+S S+ +S S+SES E
Sbjct: 734 LENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDES---SSIEDSSSDSESESEPES 790
Query: 383 KEEAEEALKEKE-KPKEEEWEKPKDAAGLE 411
+ E+ KEKE K K++ KD + L+
Sbjct: 791 ESESRRVTKEKEKKTKQDRTPLTKDVSLLD 820
Score = 43.5 bits (101), Expect = 9e-04
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 314 QAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK-HSGDDSFDEGSVSESES 372
+A+ ++S +SE + D + DSE E+ S ++ GD + D S SE
Sbjct: 665 KAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQ 724
Query: 373 ESESGQAE--EEKEEAEEALKEKEKPKEEEWEKPKD 406
+SESG+ E K A+ K K K E+ EK +
Sbjct: 725 DSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENE 760
Score = 39.7 bits (91), Expect = 0.012
Identities = 26/80 (32%), Positives = 35/80 (43%)
Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEK 393
KE K+ + K + +DS D S SESES SESG+ E EE +
Sbjct: 658 KEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSS 717
Query: 394 EKPKEEEWEKPKDAAGLECK 413
E E+ + +GLE K
Sbjct: 718 EDSSSEQDSESGRESGLENK 737
Score = 31.6 bits (70), Expect = 3.4
Identities = 21/77 (27%), Positives = 33/77 (42%)
Query: 335 EEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE 394
E KE + K + +S + ++ S S S+SESESG E+ E+ E E
Sbjct: 655 ELAKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNE 714
Query: 395 KPKEEEWEKPKDAAGLE 411
E+ + +G E
Sbjct: 715 DSSEDSSSEQDSESGRE 731
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 61.6 bits (148), Expect = 3e-09
Identities = 34/104 (32%), Positives = 64/104 (61%), Gaps = 5/104 (4%)
Query: 302 TNDKDEKKEDGKQAENDSSNDDKTKKSEGDG-DKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
+ +++E++E+ ++ E + +++ +K E +G +K+ +KE+ EK+ KK KK+ ++
Sbjct: 2245 SEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304
Query: 361 SFDEGSVSESESESESGQAEEEKEEA----EEALKEKEKPKEEE 400
F+E SE E+ES EEE+EE+ EE +EKE K+E+
Sbjct: 2305 VFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Score = 50.1 bits (118), Expect = 9e-06
Identities = 39/143 (27%), Positives = 69/143 (48%), Gaps = 26/143 (18%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
E+E EEE+ + E ++EE R K+E++ + KQ E + K KK
Sbjct: 2248 EEEREEEEEREEEEVREEEEER--------------KEEEEGEEKQVEKEEEEKKKKKKE 2293
Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEE 388
+ + +EK+E E++ + S++ S+S+ E E ES EEE + +E
Sbjct: 2294 KKKEEVQEKEEVFEEKEEIMSEEETE-----------SLSDEEEEEESCSLEEEVDREKE 2342
Query: 389 ALKEKEKPKEEEWEKPKDAAGLE 411
LK++++ K +E ++ K G E
Sbjct: 2343 ILKKEKQFKLQE-QRRKSLRGRE 2364
Score = 47.0 bits (110), Expect = 8e-05
Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 17/153 (11%)
Query: 267 ILEQEEE---EEQAGKPGEPSK-KEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322
IL+ EEE EE+ P + ++ A G E+ ++ DE + + +E S
Sbjct: 2175 ILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLL 2234
Query: 323 DKTKK-----SEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
D+ +K SE + ++EE++E E+E ++ ++R + G +E V + E E +
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEG----EEKQVEKEEEEKKKK 2290
Query: 378 QAEEEKEEA---EEALKEKEK-PKEEEWEKPKD 406
+ E++KEE EE +EKE+ EEE E D
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323
Score = 46.2 bits (108), Expect = 1e-04
Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 4/140 (2%)
Query: 271 EEEEEQAGKPGEPSKKEEGRAGAGLGDG----ERKTNDKDEKKEDGKQAENDSSNDDKTK 326
EEE + A K E +E G + +R+ + E K K E SS D+ +
Sbjct: 2162 EEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVE 2221
Query: 327 KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
E ++ E D ++ + S + + ++ +E V E E E + + EEK+
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281
Query: 387 EEALKEKEKPKEEEWEKPKD 406
+E ++K+K KE++ E+ ++
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQE 2301
Score = 41.6 bits (96), Expect = 0.003
Identities = 100/512 (19%), Positives = 203/512 (39%), Gaps = 68/512 (13%)
Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA-ENDSS 320
E + R+L++EE+ QAG+ P + E DK K E+ KQ EN S
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEE-------------EMLQEDKKLKWEEWKQVWENMLS 1530
Query: 321 NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAE 380
+ K ++ + + + ++E S + +K + + + + + +E +A+
Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590
Query: 381 EEK---EEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEI 437
EE+ +E E+ +E+ + +EE + + + R + + F + R E
Sbjct: 1591 EERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEK 1650
Query: 438 IS------------LCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNI 485
+S L K++ +VA E + ++ + V + ++E+ QN+
Sbjct: 1651 LSQEAEKLAQKRKKLAKKWE---KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707
Query: 486 RLRECELSPGVN------RDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWA 539
+E EL+ + +L+ + +N + ++V KLA ++ W
Sbjct: 1708 DWQEKELAQELEELEWDMEELSWKEEELN--QEEGKLVEEKKKLAE------EEEALAWQ 1759
Query: 540 SEPGTPPLPTSLPSQNPILKNITDYLIE--EVSAEEEELLGSSGGAPPEEPPKEGNPAEI 597
E + T L + +L + L + E EEEE LG E+ K E
Sbjct: 1760 REKLSEE-ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818
Query: 598 NVERDEKLIKVLDKLLLYLRIVHSLDYYNTCE------YPNEDEMPNRCGIIHVRGPMPP 651
+ E+L K +K++LY + + + N + E+ + N+ + H + +
Sbjct: 1819 WINSMEELTK--NKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQ 1876
Query: 652 NRISHGEVLEWQKTFEEKLT----PLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQE 707
+ G + EEKLT ++ +E L+E E + + +VE + ++
Sbjct: 1877 VKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV-------QVEDSLAKKQEK 1929
Query: 708 LGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEK 739
L ++K L +G + +R + EK
Sbjct: 1930 LAQEKMKLALEKAMVQGKKRLRGELDIAKEEK 1961
Score = 36.2 bits (82), Expect = 0.14
Identities = 57/261 (21%), Positives = 111/261 (42%), Gaps = 39/261 (14%)
Query: 153 KEFLLSLDDSVDETEAVKRYNDYKLDFRRQQM--QDFFLAHKDEEWFRSKYHPDEVGKRR 210
+E L+ + + + + + +L +R+Q+ + LA K E W S +E+ K +
Sbjct: 1774 EELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM---EELTKNK 1830
Query: 211 ----------QEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGG 260
QE + Q + ++ +NLL + ++ K L +K + G
Sbjct: 1831 MILYQKKNLAQEKKNLAQEKEKLAQRK------ENLLYNKERLTHSKKQL--VQVKNKLG 1882
Query: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERK---TNDKDEKKEDGKQAEN 317
N +IL Q EE+ K KKE+ L + E+K D KK++ E
Sbjct: 1883 MFN--KILAQVEEKLTQEKETVIKKKEK------LAETEKKLVQVEDSLAKKQEKLAQEK 1934
Query: 318 DSSNDDKT-----KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372
+K K+ G+ D ++++ E K+ ++++ R G ++ +G E+
Sbjct: 1935 MKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSR 1994
Query: 373 ESESGQAEEEKEEAEEALKEK 393
+ + Q E+E E + +L+EK
Sbjct: 1995 QRKMTQVEQELFERKLSLEEK 2015
Score = 32.7 bits (73), Expect = 1.5
Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 23/132 (17%)
Query: 285 KKEEGRAGAGLGDGERKTNDKDEK--KEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE 342
+K+ R L + R+ +K+EK +E+ K A K SE D EE+ E
Sbjct: 2136 EKKLARKQRKLANKMRRMINKEEKMTEEESKLAR---------KHSEVILDDEEEGGIEE 2186
Query: 343 KEA----KKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPK- 397
+E K+ +KR GD ++ S E ESE E EE E L E EK +
Sbjct: 2187 EEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESE----EHFSEEMESLLDELEKQES 2242
Query: 398 ---EEEWEKPKD 406
EEE E+ ++
Sbjct: 2243 LSSEEEEEREEE 2254
Score = 30.0 bits (66), Expect = 9.8
Identities = 19/85 (22%), Positives = 43/85 (50%)
Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE 329
++EEEE+ K E K+E + E ++++ + ++ E +S + ++ E
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340
Query: 330 GDGDKEEKKEDSEKEAKKSSKKRNR 354
+ K+EK+ +++ +KS + R R
Sbjct: 2341 KEILKKEKQFKLQEQRRKSLRGRER 2365
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 61.6 bits (148), Expect = 3e-09
Identities = 67/261 (25%), Positives = 119/261 (45%), Gaps = 33/261 (12%)
Query: 148 VMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVG 207
+ KTF E L D E E V + + + ++QQ + +D R K D+ G
Sbjct: 37 IKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKK----KRDTRKGRRKKDVDDDG 92
Query: 208 KRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRI 267
+ ++ L RL+ LS+ + D+ D + K +GG I
Sbjct: 93 EEKE-----LMERLKK-LSVPTS----------DEEDEVPAPKPRGGKKTKGGNVFAALI 136
Query: 268 LEQ-EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326
+Q EEEEE+ P +P+K E+ R + + ++ K + GK+ ++ + K
Sbjct: 137 QDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPA----LKGKKGKEEKSKGKAKPQNK 192
Query: 327 KSEGDGDKEEKKED--SEKEAKKSSKKRNRK-HSGDDSFDEGSVSESESESESGQAEEEK 383
+ D ++E+K+E+ EKE K K++ +K G + EG E E E G+++ +
Sbjct: 193 FAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEG----EEEEEEGGESKADD 248
Query: 384 EEAEEALKEKEKPKEE-EWEK 403
A + KEK+K K++ E+E+
Sbjct: 249 PYAHLSKKEKKKLKKQMEYER 269
Score = 33.5 bits (75), Expect = 0.89
Identities = 38/173 (21%), Positives = 69/173 (39%), Gaps = 35/173 (20%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
+Q E E G GE + + G D + K +E + KQA ++K K
Sbjct: 7 QQPPEPEWIGD-GESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQA----GEEEKVLKE 61
Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEG---------SVSESESESE---- 375
+ +++++++ +++ K+ ++K RK DD +E SV S+ E E
Sbjct: 62 K---EQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAP 118
Query: 376 --------------SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKP 414
+ +++ EE EE K KP + E + A E +P
Sbjct: 119 KPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQP 171
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 60.5 bits (145), Expect = 7e-09
Identities = 38/160 (23%), Positives = 78/160 (48%), Gaps = 10/160 (6%)
Query: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE--RKTNDKDEKKEDGKQAEND 318
T+ D + L+++++++ K E + E G A D +K + D+KK+D K+
Sbjct: 347 TKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFS 406
Query: 319 SSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
+ ++ + + E D+++ K+DS+ + KKS K D SE + +S+ G+
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDAD--------SEPKGDSKKGK 458
Query: 379 AEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLH 418
+E+K + + +K+K ++ E + + LE K H
Sbjct: 459 KDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 498
Score = 55.8 bits (133), Expect = 2e-07
Identities = 63/268 (23%), Positives = 107/268 (39%), Gaps = 31/268 (11%)
Query: 161 DSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNR 220
D +TE+ + D R+ +D KD++ +K +P+ +A+ A +
Sbjct: 325 DVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDS 384
Query: 221 LRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKP 280
L K D K DA I +E++L E +++E++ K
Sbjct: 385 RN--------------LKKASKNDD--KKKDAKKITFSTDSESELESKESQKDEKKDKKD 428
Query: 281 GEPSKKEEGRAGAGLGDGERKTNDKDEK-KEDGKQAENDSSNDDKTK-------KSEGDG 332
+ K+ + D + + +K K+D K+ + DS DDK K +E +
Sbjct: 429 SKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMES 488
Query: 333 DKEEKKEDSEKEAKKSSKK------RNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
D E KK+ + KK SKK R S D FDE S + ++ ++ ++ E EE+
Sbjct: 489 DLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEES 548
Query: 387 EEALKEKEKPKEEEWEKPKD-AAGLECK 413
K+K E + GLE K
Sbjct: 549 LYKPGAKKKIDESDGTSANSKMEGLESK 576
Score = 50.8 bits (120), Expect = 5e-06
Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 265 LRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDK 324
LR Q + + K + +KK+ + D E + D + K+D K+ + + DDK
Sbjct: 265 LRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAE--SEDSKDAKKDSKKVKKNVKKDDK 322
Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKE 384
K + D + + + K+ +K +KK +K DD + +++ESG A++ +
Sbjct: 323 KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARN 382
Query: 385 EA---EEALKEKEKPKE 398
++ ++A K +K K+
Sbjct: 383 DSRNLKKASKNDDKKKD 399
Score = 48.1 bits (113), Expect = 3e-05
Identities = 38/164 (23%), Positives = 75/164 (45%), Gaps = 27/164 (16%)
Query: 271 EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQ------AENDSSNDDK 324
+++ ++ K ++ E+ + +K KD+KK+D K+ AE+ S D++
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDER 344
Query: 325 --TKKSEGDGDKEEKKEDSE-------------KEAKKSSKKRNRKHSGDDSFDE----- 364
TKK + K++KK+D++ K+A+ S+ + DD +
Sbjct: 345 KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404
Query: 365 -GSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407
+ SESE ES+ Q +E+K++ + K+ K +E D+
Sbjct: 405 FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADS 448
Score = 45.1 bits (105), Expect = 3e-04
Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 21/147 (14%)
Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN---DDKTKKSEGDGDKE 335
K E K ++ + G L KD KK+ G A N S ++KTK+ + + DK
Sbjct: 111 KKAEYKKSKDEKGGTPL--------KKDSKKKGGSYATNPESKQIVEEKTKR-QNEADKT 161
Query: 336 EKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEK 395
K E E K SK + + +S + +VS++ S+ + ++ K+ E L K
Sbjct: 162 PLKSSHENEQSKKSK--SSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 219
Query: 396 PKEEEWEKPKDAAGLECKPRPLHKTCS 422
PK KD + P+ + CS
Sbjct: 220 PK-------KDLKRSKTSNDPISEICS 239
Score = 40.4 bits (93), Expect = 0.007
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 14/98 (14%)
Query: 317 NDSSNDDK------TKKSEGDGDKEEKKE-----DSEKEAKKSSKKRNRKHSGDDSFDEG 365
N S N+ K TK ++ D K KK + K+AKK SKK + DD +
Sbjct: 267 NYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDV 326
Query: 366 SVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
+++ESG + K+E ++ K+K+K K+++ +K
Sbjct: 327 KKDTESTDAESG---DSKDERKDTKKDKKKLKKDDKKK 361
Score = 32.0 bits (71), Expect = 2.6
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 10/109 (9%)
Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKK-EDSEKEAKKSSKKRNRKHS 357
E+K + KD KK+ K E+ + D++ K+ G K K + S+ E+++S K K
Sbjct: 501 EKKGSKKDIKKDARKDTESTDAEFDESSKT---GFKTSTKIKGSDTESEESLYKPGAKKK 557
Query: 358 GDDSFDEGSVSESES-ESESGQAEEEK-----EEAEEALKEKEKPKEEE 400
D+S + S+ E ES+ G K E+ E+A + P E+
Sbjct: 558 IDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVPPSREK 606
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 60.1 bits (144), Expect = 9e-09
Identities = 37/157 (23%), Positives = 78/157 (49%), Gaps = 4/157 (2%)
Query: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
G ++++R E+E E + GK S++++ R + ++ +K+ K+E GK+ +
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERRER---EKRKREREKERKRERGKKEKKGE 89
Query: 320 SNDDKTKKSEGDGDKEEKK-EDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
++ ++ + +KE K+ E+ EK KK K+R R + + E E +
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 379 AEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
+EE+E+ E + K++ +++ EK ++ E K R
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Score = 58.2 bits (139), Expect = 3e-08
Identities = 40/150 (26%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
E++ E + K GE K+E R ++ +K+++K+ K+ +S + K ++
Sbjct: 76 ERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135
Query: 329 EGDGDKEEKKE------DSEKE-AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
+ + +EE+KE + EKE +K KKR RK G+ + E + +E
Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
Query: 382 EKEEAE-----EALKEKEKPKEEEWEKPKD 406
K+E E E KE++K +E + E+ KD
Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKD 225
Score = 57.4 bits (137), Expect = 6e-08
Identities = 34/154 (22%), Positives = 77/154 (50%), Gaps = 4/154 (2%)
Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN 321
E + + +E+E ++ + + KKE+ G +G+ + ++ K+E+ K+ E
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
+K ++ + + K E+K+ EKE ++ K+R + + + E + E + ++
Sbjct: 154 REKERERK-ERKKRERKQVGEKEEERKEKERKERKKRERNRKER--KKERERKERRERKK 210
Query: 382 EKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
E+++ EE KE++K ++ W + K+ E K R
Sbjct: 211 ERKKKEERKKERQKDRQTNW-REKERGKRERKER 243
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 11/166 (6%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
+ EG E + ++ E E+ + E +K E G GERK +++ KK ++
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRE--RGKKEKKGERKKEERERKKRR-REK 104
Query: 316 ENDSSND-----DKTKKSEGDGDKEEKKEDSEKEAKKSSKK-RNRKHSGDDSFDEGSVSE 369
EN + K KK G KE K+ + ++E K+ +K R RK + E +
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164
Query: 370 SESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
+ G+ EEE++E E KE++K + E+ K+ E + R
Sbjct: 165 KRERKQVGEKEEERKEKER--KERKKRERNRKERKKERERKERRER 208
Score = 52.0 bits (123), Expect = 2e-06
Identities = 38/137 (27%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 276 QAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK---QAENDSSNDDKTKKSEGDG 332
Q G E ++E G ER++ K E++E K + E + + K+ +G+
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Query: 333 DKEE---KKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEA 389
KEE KK EKE K+ +K RK S E E + + EE++E E
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 390 LKEKEKPKEEEWEKPKD 406
+E+EK +E + K ++
Sbjct: 151 KEEREKERERKERKKRE 167
Score = 50.4 bits (119), Expect = 7e-06
Identities = 31/146 (21%), Positives = 73/146 (50%), Gaps = 9/146 (6%)
Query: 260 GTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
G E + R ++++E + K G+ +++E R + ERK K+E++++ ++ E
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK---KEEREKERERKERKK 165
Query: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
+ + E + ++E+KE ++E + +K+ R+ E + E + + +
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERK------ERRERKKERKKKEERK 219
Query: 380 EEEKEEAEEALKEKEKPKEEEWEKPK 405
+E +++ + +EKE+ K E E+ K
Sbjct: 220 KERQKDRQTNWREKERGKRERKERKK 245
Score = 40.0 bits (92), Expect = 0.009
Identities = 21/85 (24%), Positives = 43/85 (50%)
Query: 6 DEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRER 65
+E R R + R++ + ++ RER ER++ + E + R+ + R E + +RNR+ER
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 66 FSPPRHELSPPQKRMRRDWDEHSSD 90
+ +K+ R+ +E +
Sbjct: 197 KKERERKERRERKKERKKKEERKKE 221
Score = 37.4 bits (85), Expect = 0.061
Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF 66
E +RRR+K +E + ++ ++++++ RG R G+ER + E + +R RER
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERG-----RTSKEGKERERKEERKREERKERERK 150
Query: 67 SPPRHELSPPQKRMRRD 83
R + ++R +R+
Sbjct: 151 KEEREKERERKERKKRE 167
Score = 37.4 bits (85), Expect = 0.061
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRS--RGEYRDYDRNRRE 64
E +R+ R K R R + + RER ERR ++ +R +ER+ + +R+ +R +RE
Sbjct: 180 EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239
Query: 65 R 65
R
Sbjct: 240 R 240
Score = 35.4 bits (80), Expect = 0.23
Identities = 17/63 (26%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNR 62
+S+ + +RR R+K +RER + +R RER ++ + + E +R + RR + ++ +
Sbjct: 56 ESERKKERREREKRKRER-EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114
Query: 63 RER 65
R++
Sbjct: 115 RKK 117
Score = 33.9 bits (76), Expect = 0.68
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 8/66 (12%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER---RSRGEYRDYD 59
+ + E + R+ K RE RER++R+R +RE +R RER +GE + +
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKR-----EREKERKRERGKKEKKGERKKEE 94
Query: 60 RNRRER 65
R R++R
Sbjct: 95 RERKKR 100
Score = 32.3 bits (72), Expect = 2.0
Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNR 62
+ + E +R+ K ++ER S+E ER R + +R+ + +ER + E R+ +R R
Sbjct: 106 NKEGEEKEKRKKKEKKERG--RTSKEGKERERKE---ERKREERKERERKKEEREKERER 160
Query: 63 RERFSPPRHELSPPQKRMR 81
+ER R ++ ++ +
Sbjct: 161 KERKKRERKQVGEKEEERK 179
Score = 32.0 bits (71), Expect = 2.6
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 7/85 (8%)
Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGE-----YRDYDRN 61
E R ++ RER + + ER ER R + +RE +R R+ R + E ++ +R
Sbjct: 122 ERGRTSKEGKERERKEERKREERKERERKKE--EREKERERKERKKRERKQVGEKEEERK 179
Query: 62 RRERFSPPRHELSPPQKRMRRDWDE 86
+ER + E + +++ R+ E
Sbjct: 180 EKERKERKKRERNRKERKKERERKE 204
Score = 31.6 bits (70), Expect = 3.4
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 25 RSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDW 84
R RER+ R + +RE +R +ERR R ++ +RER + E +K+ R
Sbjct: 39 REREREIETRKEGKKERESERKKERRER------EKRKREREKERKRERGKKEKKGERKK 92
Query: 85 DE 86
+E
Sbjct: 93 EE 94
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 59.3 bits (142), Expect = 2e-08
Identities = 39/150 (26%), Positives = 76/150 (50%), Gaps = 13/150 (8%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
+G E + + +E+E E + + E ++E R + +++ +KE ++ E
Sbjct: 295 KGKKEKERQEIEKERRERERERERERERRERER---------EREREREREKEKERERER 345
Query: 318 DSSND-DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESES 376
+ D D+TK+ + D D+E + D ++E + S + ++R S + S D E E E E
Sbjct: 346 ERDRDRDRTKERDRDRDRERDR-DRDRE-RSSDRNKDRSRSREKSRDRERERERERERER 403
Query: 377 GQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
+ E E+E E +E+E+ +E E +K +D
Sbjct: 404 -EREREREREREREREREREREREKDKKRD 432
Score = 53.1 bits (126), Expect = 1e-06
Identities = 47/228 (20%), Positives = 97/228 (42%), Gaps = 26/228 (11%)
Query: 204 DEVGKRRQEARGALQNRLRVFLSLM-----ETGWFDNLLLDIDKADAIVKMLDAAVIKME 258
+E +R Q +GA++ +R + S + E+ K D + A +I
Sbjct: 198 EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYP 257
Query: 259 GGTENDLRILEQEEE-------------------EEQAGKPGEPSKKEEGRAGAGLGDGE 299
T+ D+ +E EE+ EE+ GK + ++ E + E
Sbjct: 258 LITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERE 317
Query: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGD 359
R+ ++ ++E ++ E + + + ++ E D D++ KE ++ + R+R+ S D
Sbjct: 318 RERERREREREREREREREKEKE-RERERERDRDRDRTKERDRDRDRERDRDRDRERSSD 376
Query: 360 DSFDEGSVSESESESE-SGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
+ D E + E + E E+E E +E+E+ +E E E+ ++
Sbjct: 377 RNKDRSRSREKSRDRERERERERERERERERERERERERERERERERE 424
Score = 46.2 bits (108), Expect = 1e-04
Identities = 34/160 (21%), Positives = 71/160 (44%), Gaps = 17/160 (10%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
E+E E E+ KE R D +R ++ +D ++ S + ++ ++
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397
Query: 329 EGDGDKEEKKE---DSEKE-------AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQ 378
E + ++E ++E + E+E ++ KKR+R+ +D+++ + E E+
Sbjct: 398 EREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY 457
Query: 379 AE-------EEKEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
E E+++ E KE E+ +E E K+A L+
Sbjct: 458 QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 497
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/143 (23%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER-KTNDKDEKKEDGKQAENDSS 320
E + R E+E E E+ + + ++E R D +R K D+D +E + + + S
Sbjct: 319 ERERREREREREREREREKEKERERERERDR----DRDRTKERDRDRDRERDRDRDRERS 374
Query: 321 ND---DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
+D D+++ E D+E ++E + ++ ++R R+ + + E + + +
Sbjct: 375 SDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDR- 433
Query: 378 QAEEEKEEAEEALKEKEKPKEEE 400
EE++E+A E K + K +E+E
Sbjct: 434 --EEDEEDAYERRKLERKLREKE 454
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 3 DSDDEYDRRR-RDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDR 60
+ + E +R R RD+ R + D DR RERD R + +DR DR R R +SR R+ +R
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397
Query: 61 NR-RERFSPPRHELSPPQKRMRRDWDEHSSD 90
R RER E ++R R E D
Sbjct: 398 EREREREREREREREREREREREREREREKD 428
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 9/84 (10%)
Query: 7 EYDRRRRDKFR---RERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDRNR 62
E +RR R++ R RER + +R RER+ R + +RE +R R+R R++ RD DR R
Sbjct: 306 EKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365
Query: 63 -----RERFSPPRHELSPPQKRMR 81
RER S + S +++ R
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSR 389
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/147 (19%), Positives = 70/147 (47%), Gaps = 9/147 (6%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER-----KTNDKDEKKEDGKQAENDSSND- 322
++E + ++ + K+ R+ D ER + +++ ++E ++ E + +
Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERER 421
Query: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE-SGQAEE 381
++ ++ + D+EE +ED+ + K K R ++ + + + E + E +AE
Sbjct: 422 EREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAER 481
Query: 382 EKEEAEEALKEKEKPKE--EEWEKPKD 406
E+E E KE ++ KE E+++ +D
Sbjct: 482 EEERRREMAKEAKRLKEFLEDYDDDRD 508
Score = 40.0 bits (92), Expect = 0.009
Identities = 32/145 (22%), Positives = 66/145 (45%), Gaps = 12/145 (8%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
E E+E E+ + KE R L D + +D+D+ K A D + +
Sbjct: 474 EYEKEAEREEERRREMAKEAKRLKEFLEDYD---DDRDDPKYYRGSALQKRLRDREKEME 530
Query: 329 EGDGDKEEKKEDSEKEAKK---------SSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
+ D++ +KE+ E+ ++ ++ + + + E ESE E +
Sbjct: 531 ADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK 590
Query: 380 EEEKEEAEEALKEKEKPKEEEWEKP 404
+E++E+ EE ++E+E+P+++ KP
Sbjct: 591 QEKEEKREEPMEEEEEPEQKPCLKP 615
Score = 39.7 bits (91), Expect = 0.012
Identities = 31/91 (34%), Positives = 44/91 (48%), Gaps = 13/91 (14%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-----------RS 51
+ + E +R R + RER + +R R+RD + D DRE DR R+R RS
Sbjct: 326 EREREREREREKEKERER-ERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS 384
Query: 52 RGEYRDYDRNR-RERFSPPRHELSPPQKRMR 81
R + RD +R R RER E ++R R
Sbjct: 385 REKSRDRERERERERERERERERERERERER 415
Score = 39.3 bits (90), Expect = 0.016
Identities = 41/175 (23%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 264 DLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD 323
++R ++ E E+ + E ++E + L + D D+ ++D K S+
Sbjct: 465 EIRERKKTREYEKEAEREEERRREMAKEAKRL---KEFLEDYDDDRDDPKYYRG-SALQK 520
Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
+ + E + + +E+ EKE + ++R D E E E+E +++
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQE 580
Query: 384 EEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTC---SLFMRNIAPNISRA 435
E+EE +EK++ KEE+ E+P +E + P K C +L + AP++S A
Sbjct: 581 PESEEEEEEKQE-KEEKREEP-----MEEEEEPEQKPCLKPTLRPISSAPSVSSA 629
Score = 37.7 bits (86), Expect = 0.047
Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 9/83 (10%)
Query: 11 RRRDKFRRERSDYDRSRERD-ERRRGDDWNDREWDRGRER-RSRGEYRDYDRNRRERFSP 68
+ R + +ER + +R RER+ ERR + +RE +R +E+ R R RD DR+R +
Sbjct: 300 KERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR 359
Query: 69 PRHELSPPQKRMRRDWD-EHSSD 90
R + RD D E SSD
Sbjct: 360 DR------DRERDRDRDRERSSD 376
Score = 37.4 bits (85), Expect = 0.061
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 3 DSDDEYDRRRRDKFRRERS-DYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRN 61
D + E +R R + RER + +R RER+ R + D++ DR + E R +R
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449
Query: 62 RRERFSPPRHELSPPQKRMRRDWDEHSSD 90
RE+ + + L + R R+ E+ +
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKE 478
Score = 36.6 bits (83), Expect = 0.10
Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 4 SDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-RSRGEYRDYDRNR 62
SD DR R + R+R + +R RER+ R + +RE +R RER R R +D R+R
Sbjct: 375 SDRNKDRSRSREKSRDR-EREREREREREREREREREREREREREREREREREKDKKRDR 433
Query: 63 RE 64
E
Sbjct: 434 EE 435
Score = 35.8 bits (81), Expect = 0.18
Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 6/134 (4%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
E+E E E+ + + +EE A ER+ ++ ++++ E + + + +K
Sbjct: 416 EREREREREREKDKKRDREEDEEDAY----ERRKLERKLREKEAAYQERLKNWEIRERKK 471
Query: 329 EGDGDKEEKKEDSEKE--AKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEA 386
+ +KE ++E+ + AK++ + + DD D+ + + + E++ EA
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA 531
Query: 387 EEALKEKEKPKEEE 400
+E +++EK + EE
Sbjct: 532 DERDRKREKEELEE 545
Score = 35.0 bits (79), Expect = 0.30
Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 25/116 (21%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGR--------------- 47
+ + E +R R + RER + +R RE+D++R ++ + ++R +
Sbjct: 402 ERERERERERERERERER-EREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQER 460
Query: 48 ----ERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMR---RDWDEHSSDP-YHSG 95
E R R + R+Y++ ER R E++ KR++ D+D+ DP Y+ G
Sbjct: 461 LKNWEIRERKKTREYEK-EAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG 515
Score = 33.1 bits (74), Expect = 1.2
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 11 RRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRER-----RSRGEYRDYDRNRRER 65
R R++ R + +R RER+ R + +RE +R RE+ R E Y+R + ER
Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448
Score = 32.3 bits (72), Expect = 2.0
Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 6 DEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRE 64
D + + +K ++E+ + +ER ER +RE +R RERR R R+ +R R +
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRER-------ERERERERERREREREREREREREK 337
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 58.5 bits (140), Expect = 3e-08
Identities = 50/186 (26%), Positives = 82/186 (44%), Gaps = 22/186 (11%)
Query: 251 DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310
DA + E + +++ +EEE+ Q K EP KK E + + K E+K+
Sbjct: 806 DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE--------EEKAPATPKTEEKK 857
Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRK------------HSG 358
D K+ E K K E EK ++S+ EAKK + +K
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK 917
Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAE--EALKEKEKPKEEEWEKPKDAAGLECKPRP 416
+D+ + ++ E + +A+E + AE EA EK+ KEE+ +KP++ E K +
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKE 977
Query: 417 LHKTCS 422
KT S
Sbjct: 978 DDKTLS 983
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/175 (25%), Positives = 81/175 (46%), Gaps = 15/175 (8%)
Query: 246 IVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEG--RAGAGLGDGERKTN 303
+V+ + + +E TE + ++ E+ EEE+ E K+EEG A G+ E K+
Sbjct: 446 VVEKSEKETVIVEEQTE-ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP 504
Query: 304 DKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD 363
+E K+A++ + K+ +KEE K +E ++ + +K ++
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE------- 557
Query: 364 EGSVSESESESESGQAEEEKEEAEEALKEKEK-PKEEEWEKPKDAAGLECKPRPL 417
++S E++S + EE K AE EK K P +EE + P +A E P+
Sbjct: 558 ----AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV 608
Score = 51.2 bits (121), Expect = 4e-06
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 6/152 (3%)
Query: 269 EQEEEEEQAGKPGEPSKK-EEGRAGAGLGDGERKTNDKDEKKEDGKQA---ENDSSNDDK 324
+++ ++E+A K P K EE + A E K K E+ ED K+ E ++ +
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915
Query: 325 TKKSEGDGDKEE--KKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
K+ +K E KKE + +AK+ SK +K + + D + E + +
Sbjct: 916 VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA 975
Query: 383 KEEAEEALKEKEKPKEEEWEKPKDAAGLECKP 414
KE+ + KE KPK E+ EK + KP
Sbjct: 976 KEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
Score = 47.4 bits (111), Expect = 6e-05
Identities = 43/166 (25%), Positives = 73/166 (43%), Gaps = 34/166 (20%)
Query: 247 VKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKD 306
+K+ IK+ +E + I+E++ EE Q + E +++EE K+
Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTE--EVTEEEE----------------KE 477
Query: 307 EKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366
K+E+GK+ E + + + E E+ EKEAK K+
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEE-------------- 523
Query: 367 VSESESESESGQAEEEKEEAEEALKEKEK-PKEEEWEKPKDAAGLE 411
++S +E++S + EE K AE EK K P +EE + P +A E
Sbjct: 524 -AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/141 (28%), Positives = 61/141 (43%), Gaps = 8/141 (5%)
Query: 274 EEQAGKPGEPS--KKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
+E+A P E +KEE ++ A + E+ K KE+ K S + + KS +
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPPEAKSPEKEEAKSPAE 577
Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK 391
EK + KE KS + E ++S +E++S EE K AE
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE--EAKSPAEAKSPVKEEAKSPAEVKSP 635
Query: 392 EKEK-PKEEEWEKPKDAAGLE 411
EK K P +EE + P+ A E
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPE 656
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 15/148 (10%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSK------KEEGRAGAGLGDGERKTNDKDEKKED 311
EGG E + E+E + A + P K KEE ++ A E K+ +K+E K
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA-----EAKSPEKEEAKSP 541
Query: 312 GKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE 371
AE S K+ E E K ++EAK ++ ++ + + + +E S +E
Sbjct: 542 ---AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPAE 597
Query: 372 SESESGQAEEEKEEAEEALKEKEKPKEE 399
++S KEEA+ + K KEE
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEE 625
Score = 40.8 bits (94), Expect = 0.006
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEE--EEQAGKPGEPSKKEEGRAGAGLGDG 298
+KA + VK + K + + + + E+ + +E+A P E +K E +
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP-EKAKSPEKAKTLDVKSP 764
Query: 299 ERKTNDKDEKKEDGKQ--------AENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSK 350
E KT K+E + + + + + +K K + K +KE +KE KS
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 351 KRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407
K K + +E E + + EE+K+ +E +KE PK + EK + A
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Score = 40.4 bits (93), Expect = 0.007
Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 15/156 (9%)
Query: 273 EEEQAGKPGEPSKKEEGRAGA---GLGDGERKTNDKDEKKE--DGKQAENDSSNDDKTKK 327
E+E+A P E E+ ++ A E K+ +K+E K + K E S + K
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 328 SEGDGDKEEK-KEDSEKEAK-----KSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
S + EK K ++EAK KS K K + E + S ++ E++S + +
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 382 --EKEEAEEALKEKEKPKEE--EWEKPKDAAGLECK 413
EKEEA+ K K K E EK K E K
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689
Score = 40.0 bits (92), Expect = 0.009
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 275 EQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDK 334
E+A P + K +A + L + + + KKE+ K + + K E
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 335 EEKKEDS--EKEAKKSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEAL 390
EE+K + + E KK SKK +K + +E E ES + E +KEEAE+
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES-KVEAKKEEAED-- 899
Query: 391 KEKEKPKEEEWEKPKDAAGLECKPR 415
+K+ P E+ K + KP+
Sbjct: 900 -KKKVPTPEKEAPAKVEVKEDAKPK 923
Score = 39.7 bits (91), Expect = 0.012
Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 4/136 (2%)
Query: 274 EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGD 333
+E+A P E E+ ++ + + K KE+ K S + ++ +
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVK-EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647
Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE--KEEAEEALK 391
EK + EKE KS +K + E + S ++E++S + + KEEA+ K
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEK 707
Query: 392 EKEKPKEEEWEKPKDA 407
K P +EE + P+ A
Sbjct: 708 AK-SPVKEEAKSPEKA 722
Score = 38.9 bits (89), Expect = 0.021
Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 14/149 (9%)
Query: 274 EEQAGKPGEPSK--KEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
+E+A P E KEE ++ A + E+ K KE+ K E S + + KS
Sbjct: 609 KEEAKSPAEAKSPVKEEAKSPAEVKSPEKA---KSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK--EEAEEA 389
K E E KS K K ++S +++S EE K E+A+
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 390 LKEKEK-------PKEEEWEKPKDAAGLE 411
+KE+ K P +EE + P+ A E
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754
Score = 37.4 bits (85), Expect = 0.061
Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 18/154 (11%)
Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGER-KTNDKDEK----------------KEDGKQ 314
+EE ++ + +KEE ++ A + E+ K+ K+E KE+ K
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS 614
Query: 315 AENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESES 374
S + KS + EK + KE KS +K + E + S ++E+
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 375 ESGQAEEEKEEAEEALKEKEK-PKEEEWEKPKDA 407
+S + + +AE EK K P +EE + P+ A
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708
Score = 35.4 bits (80), Expect = 0.23
Identities = 33/145 (22%), Positives = 53/145 (36%), Gaps = 5/145 (3%)
Query: 274 EEQAGKPGE---PSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG 330
+E+A P E P K + + K+ +K+E K K + +K++
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682
Query: 331 DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES--ESESGQAEEEKEEAEE 388
E K + K K K K + S +++S + E+ E+ K +E
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Query: 389 ALKEKEKPKEEEWEKPKDAAGLECK 413
K EK K E K D E K
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAK 767
Score = 35.4 bits (80), Expect = 0.23
Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 2/137 (1%)
Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
+EE ++ + + +KEE ++ + EK + +AE S K+ E
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702
Query: 332 GDKEEKKEDSEKEAKKSSKKRN--RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEA 389
E+ K ++EAK K ++ ++ + + V E E ++ E+ + +
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762
Query: 390 LKEKEKPKEEEWEKPKD 406
E + P +EE P D
Sbjct: 763 SPEAKTPAKEEARSPAD 779
Score = 32.3 bits (72), Expect = 2.0
Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 14/135 (10%)
Query: 272 EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
+EE ++ + + KEE ++ E+ + E+ + ++A++ + K+ +
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSP------EKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS 752
Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK 391
+K + + EAK +K+ R S D F E + S + E +S E+A+ LK
Sbjct: 753 PEKAKTLDVKSPEAKTPAKEEAR--SPADKFPEKAKSPVKEEVKS------PEKAKSPLK 804
Query: 392 EKEKPKEEEWEKPKD 406
E K E+E K ++
Sbjct: 805 EDAKAPEKEIPKKEE 819
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 58.2 bits (139), Expect = 3e-08
Identities = 47/182 (25%), Positives = 83/182 (45%), Gaps = 8/182 (4%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
K E G E + + E+E++ ++ + +K+E + G R+ K E+KE ++
Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE--RER 125
Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
EN + K KK ++E+K + E+ K+ K++ RK + E + E + E E
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRKERKKERE 184
Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRA 435
+ E K+E + KE+ K KE + ++ D RPL + S F R + R
Sbjct: 185 RKERRERKKERK---KERRKKKERKKDRKTDRQTDSQVFRPLRE--SAFNRVTVTGVFRY 239
Query: 436 EI 437
I
Sbjct: 240 RI 241
Score = 53.9 bits (128), Expect = 6e-07
Identities = 34/138 (24%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
+++ ++ + GK E +KE + + ER+ K++KK + KQ ++ KK
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ----RGRRERKKKK 118
Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEE 388
E + E K+ E++ KK KK+ RK + E E + + + E+K E
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREK--ERGKRERKRKKRKKEEREKKRERNR 176
Query: 389 ALKEKEKPKEEEWEKPKD 406
++KE+ ++E E+ K+
Sbjct: 177 KERKKERERKERRERKKE 194
Score = 52.4 bits (124), Expect = 2e-06
Identities = 29/147 (19%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKS 328
++E E+E+ + G+ KK+ + G + ERK ++++++++ ++ E +K K+
Sbjct: 47 KREREKERKRERGKKEKKKRKKRERGK-ERERKRKEREKQRKERREKERRKRKKEKKKRE 105
Query: 329 EGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEE 388
+ E+K+ E++ ++ K+ R+ + E + E E G+ E ++++ ++
Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165
Query: 389 ALKEKEKPKEEEWEKPKDAAGLECKPR 415
+EK++ + + E+ K+ E + R
Sbjct: 166 EEREKKRERNRK-ERKKERERKERRER 191
Score = 49.7 bits (117), Expect = 1e-05
Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 271 EEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG 330
+ E E+ + E K++ R + +K K +K+E GK+ E K+ E
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER--------KRKER 82
Query: 331 DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEAL 390
+ ++E++E ++ KK KKR RK G E + + E + E E ++ E
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGR--------RERKKKKERKERERENKQRRERK 134
Query: 391 KEKEKPKEEEWEKPKD 406
++K + K+ E+ ++
Sbjct: 135 RKKRRKKKRRKERKRE 150
Score = 38.1 bits (87), Expect = 0.036
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 13/93 (13%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRE--------RDERRRGDDWNDREWDRGRERRSRGE 54
+S+ + +RR R+K +RER + +R RE R +R RG + + +R ++R+ R E
Sbjct: 33 ESERKKERREREKRKRER-EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 55 ----YRDYDRNRRERFSPPRHELSPPQKRMRRD 83
R ++ +RER R E ++R R+
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERE 124
Score = 37.4 bits (85), Expect = 0.061
Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 13/97 (13%)
Query: 313 KQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESES 372
K S K ++ +E +KE + KK KKR ++ G
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG-------------K 73
Query: 373 ESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
E E + E EK+ E KE+ K K+E+ ++ + G
Sbjct: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
Score = 37.4 bits (85), Expect = 0.061
Identities = 25/105 (23%), Positives = 52/105 (49%), Gaps = 8/105 (7%)
Query: 302 TNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDS 361
T + E+K++ ++ E +K +K E G KE+KK ++ ++ K+R RK
Sbjct: 30 TQRESERKKERREREKRKREREKERKRER-GKKEKKK----RKKRERGKERERKRK---E 81
Query: 362 FDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
++ E E + E++K E ++ + + K K+E E+ ++
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Score = 37.0 bits (84), Expect = 0.080
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 9 DRRRRDKFRRERSDYDRSRE--RDERRRGDDWNDRE---WDRGRERRSRGEYRDYDRNRR 63
+R R +K RRER R ++ R ER+R + RE R +E R + R+ ++
Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181
Query: 64 ERFSPPRHELSPPQKRMRRDWDEHSSD 90
ER R E +K+ RR E D
Sbjct: 182 ERERKERRERKKERKKERRKKKERKKD 208
Score = 36.6 bits (83), Expect = 0.10
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 10 RRRRDKFR-RERSDYDRSRERDERRRGDDWNDREWDRGRERRSRG---EYRDYDRNRRER 65
R++R++ + RER +R ++R ERR + ++ + RER+ RG + +R RER
Sbjct: 66 RKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125
Query: 66 FSPPRHELSPPQKRMRR 82
+ R E ++R ++
Sbjct: 126 ENKQRRERKRKKRRKKK 142
Score = 36.6 bits (83), Expect = 0.10
Identities = 19/76 (25%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF 66
E R+ R+K R+ER + +R + + E+++ +R+ RER+ + E ++ +R ++R
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKK----RERKQRGRRERKKKKERKERERENKQRR 131
Query: 67 SPPRHELSPPQKRMRR 82
R + ++R R
Sbjct: 132 ERKRKKRRKKKRRKER 147
Score = 35.0 bits (79), Expect = 0.30
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query: 10 RRRRDKFRRERSDYDRSRERDERRRGDDWNDRE-WDRGRERRSRGEYRDYDRNRRERFSP 68
+ RR+K RR+R + RER +R R + +E +R RE + R E + R +++R
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 69 PRHELSPPQKRMRR 82
+ E ++ +R
Sbjct: 147 RKREKERGKRERKR 160
Score = 33.9 bits (76), Expect = 0.68
Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 3 DSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDY---- 58
+ + E R R K +++R +R +ER ER+R + R+ R +ERR R + +
Sbjct: 49 EREKERKRERGKKEKKKRKKRERGKER-ERKRKEREKQRKERREKERRKRKKEKKKRERK 107
Query: 59 DRNRRERFSPPRHELSPPQKRMRRD 83
R RRER + + + RR+
Sbjct: 108 QRGRRERKKKKERKERERENKQRRE 132
Score = 33.1 bits (74), Expect = 1.2
Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Query: 5 DDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGE-------YRD 57
+ E +R+++K +RER R + ++ R + + + R R+R+ R + R+
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 58 YDRNRRERFSPPRHELSPPQKRMR 81
+R +RER R + +KR R
Sbjct: 151 KERGKRERKRKKRKKEEREKKRER 174
Score = 30.8 bits (68), Expect = 5.7
Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
E R++R K RE+ +ER + R + +R+ +R +ERR + E R DR
Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKE-RKKDR 209
Score = 30.0 bits (66), Expect = 9.8
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 10 RRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPP 69
+ R+K +RER+ +R +ER+ + R + +R+ +R R+++ R + R DR + P
Sbjct: 165 KEEREK-KRERNRKERKKERERKERRERKKERKKER-RKKKERKKDRKTDRQTDSQVFRP 222
Query: 70 RHE 72
E
Sbjct: 223 LRE 225
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 58.2 bits (139), Expect = 3e-08
Identities = 41/148 (27%), Positives = 71/148 (47%), Gaps = 23/148 (15%)
Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325
+ L + EE+ E K E +++ K EKK+ G+ + + SS+ D +
Sbjct: 46 KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 105
Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
S + +++ +K+ K+ KK+NR H +S S+SE+ES+S
Sbjct: 106 SSS------SDSEDEDKKQGKRRKKKKNRSHKSSES----SMSETESDS----------- 144
Query: 386 AEEALKEKEKPKEEEWEKPKDAAGLECK 413
+++LK+K+K K+ EK KD GL K
Sbjct: 145 -KDSLKKKKKSKDGT-EKEKDIKGLSKK 170
Score = 58.2 bits (139), Expect = 3e-08
Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 19/167 (11%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE----------RKTNDK 305
K+ G+E+ + +++++E++ S + + D E +K ++
Sbjct: 69 KLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNR 128
Query: 306 DEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEG 365
K + +E +S + D KK + D EK EK+ K SKKR + +S D
Sbjct: 129 SHKSSESSMSETESDSKDSLKKKKKSKDGTEK----EKDIKGLSKKR-KMYSEDKPLSSE 183
Query: 366 SVSES----ESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408
S+SES E ++ ++ EE+E+A E K+K+K K+ +K K AA
Sbjct: 184 SLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 230
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 58.2 bits (139), Expect = 3e-08
Identities = 41/148 (27%), Positives = 71/148 (47%), Gaps = 23/148 (15%)
Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325
+ L + EE+ E K E +++ K EKK+ G+ + + SS+ D +
Sbjct: 56 KALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS 115
Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
S + +++ +K+ K+ KK+NR H +S S+SE+ES+S
Sbjct: 116 SSS------SDSEDEDKKQGKRRKKKKNRSHKSSES----SMSETESDS----------- 154
Query: 386 AEEALKEKEKPKEEEWEKPKDAAGLECK 413
+++LK+K+K K+ EK KD GL K
Sbjct: 155 -KDSLKKKKKSKDGT-EKEKDIKGLSKK 180
Score = 58.2 bits (139), Expect = 3e-08
Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 19/167 (11%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGE----------RKTNDK 305
K+ G+E+ + +++++E++ S + + D E +K ++
Sbjct: 79 KLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNR 138
Query: 306 DEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEG 365
K + +E +S + D KK + D EK EK+ K SKKR + +S D
Sbjct: 139 SHKSSESSMSETESDSKDSLKKKKKSKDGTEK----EKDIKGLSKKR-KMYSEDKPLSSE 193
Query: 366 SVSES----ESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408
S+SES E ++ ++ EE+E+A E K+K+K K+ +K K AA
Sbjct: 194 SLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 240
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/168 (25%), Positives = 87/168 (51%), Gaps = 11/168 (6%)
Query: 248 KMLDAAVIKMEGGTENDLRILEQEEEEEQAG-KPGEPSKKEEGRAGAGLGDGERKTNDKD 306
K L+ + K+ G E+ + E++++ ++ + S + + + + E K K
Sbjct: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKR 130
Query: 307 EKKEDGK--QAENDSSNDDKTKKSEGDGDKEEKKEDSEKE--AKKSSKKRNRKHSGDDSF 362
KK+ + ++ S+++ +++ E K++ K+++EKE + SKKR + + D
Sbjct: 131 RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPL 190
Query: 363 DEGSVSESESESESGQAE-----EEKEEAEEALKEKEKPKEEEWEKPK 405
S SES+ E E QA+ EE+E+A+E +K+K+K + ++ K K
Sbjct: 191 SSESSSESDYE-EDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKK 237
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/148 (27%), Positives = 63/148 (42%), Gaps = 24/148 (16%)
Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKT 325
+ L + EE+ E K E +++ K KK+ + + + SS+D +
Sbjct: 56 KALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSS 115
Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEE 385
S DSE E KK K+R +K + + S ESESES
Sbjct: 116 SSS-----------DSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESES----------- 153
Query: 386 AEEALKEKEKPKEEEWEKPKDAAGLECK 413
+E++K+K+K K+E EK KD L K
Sbjct: 154 -KESVKKKKKSKDET-EKEKDVRSLSKK 179
Score = 39.3 bits (90), Expect = 0.016
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 269 EQEEEEEQAGKPGEPSKKEEGRAG--AGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK 326
E E E +++ K + SK E + L +K+ D+ +E+D D + K
Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
Query: 327 KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370
K + E++E ++++ KK KK+++KHS GS +S
Sbjct: 208 KKR----RCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 57.4 bits (137), Expect = 6e-08
Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 13/140 (9%)
Query: 258 EGGTENDLRILEQEEE-------EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310
+GGTE D + +++ + E QA K E K E+G+ A GD E K KD K+
Sbjct: 210 KGGTEKDSKKGKKDSKKGKDSAIELQAVKADE-KKDEDGKKDANKGD-ESKDAKKDAKEI 267
Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFD--EGSVS 368
K+ + D T D K+E K+D+ K+AKK +KK K S D D + +
Sbjct: 268 --KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKK 325
Query: 369 ESESESESGQAEEEKEEAEE 388
+++ +++ ++EK++A++
Sbjct: 326 DAKKDAKKNAKKDEKKDAKK 345
Score = 57.0 bits (136), Expect = 7e-08
Identities = 44/150 (29%), Positives = 78/150 (52%), Gaps = 18/150 (12%)
Query: 269 EQEEEEEQAGKPGEPSKKE--EGRAGAGLGDGERKTNDKDEKK--EDGKQAENDSSNDDK 324
E E+E+ A K + KK+ +G+ A +GE+ +KD KK +D K+ ++ +
Sbjct: 177 ESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA 236
Query: 325 TK---KSEGDGDKEEKKEDSEKEAKKSSK--KRNRKHSGDDSFDEGSVSESESESESGQA 379
K K + DG K+ K D K+AKK +K K+ +K D+ S ++S+S+
Sbjct: 237 VKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKK-------DKKKPSSTDSDSKDDVK 289
Query: 380 EEEKEEAEEALKE--KEKPKEEEWEKPKDA 407
+E K++A + K+ K+ ++E + KDA
Sbjct: 290 KESKKDATKDAKKVAKKDTEKESADSKKDA 319
Score = 55.1 bits (131), Expect = 3e-07
Identities = 38/144 (26%), Positives = 71/144 (49%), Gaps = 8/144 (5%)
Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327
+E+ +EE+ K + SKK + A G ++K K+D K+ + DS N K
Sbjct: 147 IEKGKEEKLDAK--KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDS-NKGKDSA 203
Query: 328 SEGDGDKEEKKEDSEKEAKKSSKKRN-----RKHSGDDSFDEGSVSESESESESGQAEEE 382
+E +G+K ++DS+K K S K ++ + D+ DE ++ ES A+++
Sbjct: 204 TESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD 263
Query: 383 KEEAEEALKEKEKPKEEEWEKPKD 406
+E ++ K+K+KP + + D
Sbjct: 264 AKEIKKGKKDKKKPSSTDSDSKDD 287
Score = 53.5 bits (127), Expect = 8e-07
Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 14/141 (9%)
Query: 266 RILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKK----EDGKQAENDSSN 321
R +E + + + GK GE ++ + + E K KD KK E GK+ + D+
Sbjct: 103 RTVEVDSKAAEIGKKGEDKTTQKDTTDS---ESELKQGKKDSKKGKDIEKGKEEKLDAKK 159
Query: 322 DDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
D +KK + D +K + ++ K +KK N+K D ++G S +ESE E G E+
Sbjct: 160 D--SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDS--NKGKDSATESEGEKGGTEK 215
Query: 382 EKEEAEEALKEKEKPKEEEWE 402
+ ++ + K+ +K K+ E
Sbjct: 216 DSKKGK---KDSKKGKDSAIE 233
Score = 50.8 bits (120), Expect = 5e-06
Identities = 37/148 (25%), Positives = 77/148 (52%), Gaps = 9/148 (6%)
Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGA----GLGDGERKTNDKDEKKEDGKQAENDSSND- 322
L+Q +++ + GK E K+E+ A G D E+ + E +++ A+ D+ D
Sbjct: 134 LKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK 193
Query: 323 -DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEE 381
D K + + E +K +EK++KK K++ K D + + +V E + E G+ +
Sbjct: 194 KDSNKGKDSATESEGEKGGTEKDSKKG--KKDSKKGKDSAIELQAVKADEKKDEDGKKDA 251
Query: 382 EK-EEAEEALKEKEKPKEEEWEKPKDAA 408
K +E+++A K+ ++ K+ + +K K ++
Sbjct: 252 NKGDESKDAKKDAKEIKKGKKDKKKPSS 279
Score = 38.5 bits (88), Expect = 0.028
Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 7/82 (8%)
Query: 279 KPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS------SNDDKTKKSEGDG 332
K G+ KK+ + D +K + KD K+ K A+ D+ S D K ++ D
Sbjct: 268 KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDA 327
Query: 333 DKEEKKEDSEKEAKKSSKKRNR 354
K+ KK +++K+ KK +KK+ +
Sbjct: 328 KKDAKK-NAKKDEKKDAKKKGK 348
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 57.0 bits (136), Expect = 7e-08
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 12/110 (10%)
Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTK-KSEGDGDKEEKKEDSEKEAKKSSKKRNRKHS 357
E K +D+K+E K + + +DKT K E KEE K++ +KE KK KK +K
Sbjct: 641 ETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEV 700
Query: 358 GDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDA 407
+ E+ + + E +KEE +E KE+++PK+E + PKDA
Sbjct: 701 -----------KKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDA 739
Score = 51.2 bits (121), Expect = 4e-06
Identities = 43/146 (29%), Positives = 67/146 (45%), Gaps = 7/146 (4%)
Query: 261 TENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS 320
TE + + EE E K G ++ GAG + +T D +EK E + E +
Sbjct: 899 TEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESS-ETGDYEEKAETEEAEEPEED 957
Query: 321 NDDKTKKSEGDGDKEEKKEDSEKEAKKSSK-KRNRKHSGDDSFDEGSVSESESESESGQA 379
++ S E +E ++ EA + KR SGDD +E + + E G+A
Sbjct: 958 GEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEE----DMDEAIEKGEA 1013
Query: 380 EEEKEEAEEALKEKEKPKEEEWEKPK 405
E+ +EEA+E K E +EEE+E K
Sbjct: 1014 EQSEEEADEEDK-AEDAREEEYEPEK 1038
Score = 45.4 bits (106), Expect = 2e-04
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 11/142 (7%)
Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327
++ E+++E+ KP + K+E + + +K K E K++ K+ E + K+
Sbjct: 644 VKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKE 703
Query: 328 SEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAE 387
+ K+E K++ +KE KK K+ + E +++ S E K+ A
Sbjct: 704 TPPKEVKKEVKKEEKKEVKKEEKEPKK---------EIKKLPKDAKKSSTPLSEAKKPA- 753
Query: 388 EALKEKEKPKEEEWEKPKDAAG 409
ALK K KEE +K AAG
Sbjct: 754 -ALKPKVPKKEESVKKDSVAAG 774
Score = 37.7 bits (86), Expect = 0.047
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 6/119 (5%)
Query: 305 KDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDE 364
K E K + E S + K+E +++ + K AK+ + K+ K +D +E
Sbjct: 595 KTETKPSVTEKEVPSKEEPSPVKAEVA--EKQATDVKPKAAKEKTVKKETKVKPEDKKEE 652
Query: 365 GSVSESE---SESESGQAEEEKEEAEEALKE-KEKPKEEEWEKPKDAAGLECKPRPLHK 419
+ E E ++ +EEK + EE KE K++ K+EE ++PK E P+ + K
Sbjct: 653 KEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKK 711
Score = 37.0 bits (84), Expect = 0.080
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Query: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS-VSESESESESGQ 378
S D+ +EG+G+ E+ E+ E K+ + F+E S + E ++E+ +
Sbjct: 891 SPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEE 950
Query: 379 AEEEKEEAEEAL---KEKEKPKEEE 400
AEE +E+ EE + K P E+E
Sbjct: 951 AEEPEEDGEEHVCVSASKHSPTEDE 975
Score = 33.5 bits (75), Expect = 0.89
Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 18/142 (12%)
Query: 273 EEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK--QAENDSSNDDKTKKSEG 330
E+E++ K + E R GD +R D DE E G+ Q+E ++ +DK + +
Sbjct: 973 EDEESAKAEADAYIREKRESVASGD-DRAEEDMDEAIEKGEAEQSEEEADEEDKAEDARE 1031
Query: 331 DGDKEEKKE---------DSEKEAKKSSKKRN-----RKHSGDDSFDEGSVSESESESES 376
+ + EK E D EA + ++ K G S S E+
Sbjct: 1032 EEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLP 1091
Query: 377 GQAEEEKEEAEEALKEKEKPKE 398
G +E E ++E +E ++P+E
Sbjct: 1092 GGSESEATASDEENRE-DQPEE 1112
Score = 32.7 bits (73), Expect = 1.5
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 8/118 (6%)
Query: 283 PSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSE 342
P+K+ E + E T D +E K + E D + D K + E D+E+ KE
Sbjct: 819 PAKELEAERSL-MSSPEDLTKDFEELKAE----EVDVTKDIKPQL-ELIEDEEKLKETEP 872
Query: 343 KEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAE-EALKEKEKPKEE 399
EA K+R +S DEG ++ +E E E Q EE E E + + + EK ++E
Sbjct: 873 VEAYVIQKEREVTKGPAESPDEG-ITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDE 929
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 57.0 bits (136), Expect = 7e-08
Identities = 45/164 (27%), Positives = 77/164 (46%), Gaps = 8/164 (4%)
Query: 251 DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKE 310
+ A + EG T+ + ++E +E EE+A E + E +GE + +D
Sbjct: 1944 EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDV--- 2000
Query: 311 DGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES 370
+ +AE + ++ + E DG + + K SE E + + +K GD + V
Sbjct: 2001 EAPEAEGEMQEAEEEAQPESDGVEAQPK--SEGEEAQEVEGETQKTEGDAQPESDGVEAP 2058
Query: 371 ESESESGQAEEEKEEAE-EALKEKE--KPKEEEWEKPKDAAGLE 411
E+E E+ +AE E +EAE EA E E +E E E ++ G+E
Sbjct: 2059 EAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE 2102
Score = 48.1 bits (113), Expect = 3e-05
Identities = 40/165 (24%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGK-Q 314
++EG T+ + E + +A + E +++ EG G+ ++ D D ++ +G+ Q
Sbjct: 2036 EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQ 2095
Query: 315 AENDSSN----DDKTKKSEG----DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366
E++ + + +K+EG + + E + E EA ++ + + G ++ D +
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQD--A 2153
Query: 367 VSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
E++ ESE +A+E +EEA+ L+ E P E E E ++ G+E
Sbjct: 2154 EGEAQPESEGIEAQEAEEEAQPELEGVEAP-EAEGEAQPESEGIE 2197
Score = 46.6 bits (109), Expect = 1e-04
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 8/142 (5%)
Query: 274 EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGD 333
+E+ GK + E AG+ LG+ E++ E+ E G Q N + GD D
Sbjct: 1770 QEREGK----THNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825
Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFD-EGSVSESESESESGQAEEEKEEAE-EALK 391
+ EA ++ + + G ++ + EG E+E E++ + E EAE EA
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885
Query: 392 EKE--KPKEEEWEKPKDAAGLE 411
E E + E EWE ++ G E
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAE 1907
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 9/158 (5%)
Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA----EN 317
E +++ E+E + E G +P K EG + +KT + + DG +A E
Sbjct: 2006 EGEMQEAEEEAQPESDGVEAQP--KSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEE 2063
Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSES-ESESES 376
+ + +++EG+ E + D++ EA+ ++ + ++ E +E E+
Sbjct: 2064 AQEAEGEVQEAEGEAHPESEDVDAQ-EAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETE 2122
Query: 377 GQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKP 414
G+A+ E E E E E E E + +DA G E +P
Sbjct: 2123 GEAQPESEGIEAPEAEGEAQPESEGVEAQDAEG-EAQP 2159
Score = 43.9 bits (102), Expect = 7e-04
Identities = 36/172 (20%), Positives = 78/172 (45%), Gaps = 6/172 (3%)
Query: 238 LDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD 297
++ +A+ + + V + EG + ++ +E E +A E + E A +
Sbjct: 2055 VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAE 2114
Query: 298 GERKTNDKDEKKEDGKQAENDSSNDDKTKKSEG----DGDKEEKKEDSEKEAKKSSKKRN 353
G + E + + + E + + +SEG D + E + E EA+++ ++
Sbjct: 2115 GIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQ 2174
Query: 354 RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPK 405
+ G ++ + + E++ ESE +A E + EA+ L+ E P+ EE +P+
Sbjct: 2175 PELEGVEAPE--AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224
Score = 39.7 bits (91), Expect = 0.012
Identities = 41/169 (24%), Positives = 72/169 (42%), Gaps = 14/169 (8%)
Query: 251 DAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGD---GERKTN-DKD 306
DA + EG T N E E + G + E G G+G D GE D+D
Sbjct: 1766 DAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQD 1825
Query: 307 EKKEDGKQA-ENDSSNDDKTKKSEG------DGDKEEKKEDSEKEAKKSSKKRNRKHSGD 359
+ DG + E + + +SEG +GD +E + +++ E++ +
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885
Query: 360 DSFDEGSVS---ESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPK 405
+S D + E + ESE +A E ++EA+ + E + E ++P+
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPE 1934
Score = 39.7 bits (91), Expect = 0.012
Identities = 41/187 (21%), Positives = 85/187 (45%), Gaps = 18/187 (9%)
Query: 239 DIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRA-----GA 293
D++ +A +M +A + E E+D + + E E+A + ++K EG A G
Sbjct: 1999 DVEAPEAEGEMQEA---EEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGV 2055
Query: 294 GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEE---KKEDSEKEAKKSSK 350
+ E + + + + ++ + + S D +++EG+ E + ++E EA+K+
Sbjct: 2056 EAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115
Query: 351 KRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKE------KPKEEEWEKP 404
+ G+ + + E+E E+ Q E E EA++A E + + +E E E
Sbjct: 2116 IEAPETEGEAQPESEGIEAPEAEGEA-QPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQ 2174
Query: 405 KDAAGLE 411
+ G+E
Sbjct: 2175 PELEGVE 2181
Score = 38.9 bits (89), Expect = 0.021
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 16/112 (14%)
Query: 287 EEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAK 346
+EG G GL E ++ K E+G Q E ++TK++EG+G +EE+ + E E
Sbjct: 1307 KEGTEGEGLQ--EEAVQLEETKTEEGLQEEGVQL--EETKETEGEGQQEEEAQLEEIE-- 1360
Query: 347 KSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKE 398
+G + E V + E E + + E EE LKE+ P+E
Sbjct: 1361 ---------ETGGEGLQEEGV-QLEEVKEGPEGGLQGEALEEGLKEEGLPEE 1402
Score = 38.5 bits (88), Expect = 0.028
Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 11/145 (7%)
Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKK 327
+E E E +A E + E A +GE + +D + + + S D +T +
Sbjct: 1835 IEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPE 1894
Query: 328 SEGDGDKEEK---KEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESES-----GQA 379
+E + E + ++EKEA+ ++ + + E +E++ E+ GQ
Sbjct: 1895 AEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQT 1954
Query: 380 EEEKE--EAEEALKEKEKPKEEEWE 402
+ E E E++EA +E+ +P+ E+ E
Sbjct: 1955 QPESEVIESQEA-EEEAQPESEDVE 1978
Score = 37.7 bits (86), Expect = 0.047
Identities = 37/163 (22%), Positives = 70/163 (42%), Gaps = 7/163 (4%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
E + ++++ E +E E G E + EE + GL + + + E + +G+Q E
Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEE 1353
Query: 318 DSSNDDKTKKSEGDGDK----EEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESE 373
+ + EG ++ EE KE E + + + K G +EGSV E
Sbjct: 1354 AQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLP--EEGSVHGQEL- 1410
Query: 374 SESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRP 416
SE+ + + + ++ ++E+E + +P A G E P
Sbjct: 1411 SEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEP 1453
Score = 37.4 bits (85), Expect = 0.061
Identities = 28/129 (21%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query: 273 EEEQAGKPGEPSKKE-EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGD 331
E +A K +P + E G + E + + E +E ++AE + + + +S+ +
Sbjct: 1907 EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ-E 1965
Query: 332 GDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALK 391
++E + E + EA + + ++ G+ + V E+E E +AEEE + + ++
Sbjct: 1966 AEEEAQPESEDVEALEVEVE-TQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVE 2024
Query: 392 EKEKPKEEE 400
+ K + EE
Sbjct: 2025 AQPKSEGEE 2033
Score = 37.4 bits (85), Expect = 0.061
Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 22/149 (14%)
Query: 268 LEQEEEEEQAGKPGEPSKKEEGRAGA-GLGDGERKTNDKDEKKEDGK-QAENDSSNDDKT 325
LE E E+E + E + EE A G E + + E +E+ + ++E+ + + +
Sbjct: 1925 LETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEV 1984
Query: 326 KKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE---SGQAEEE 382
+ E +G+ + + ED E EG + E+E E++ G +
Sbjct: 1985 ETQEAEGEAQPESEDVEAPEA-----------------EGEMQEAEEEAQPESDGVEAQP 2027
Query: 383 KEEAEEALKEKEKPKEEEWEKPKDAAGLE 411
K E EEA + + + ++ E + ++ G+E
Sbjct: 2028 KSEGEEAQEVEGETQKTEGDAQPESDGVE 2056
Score = 32.0 bits (71), Expect = 2.6
Identities = 36/189 (19%), Positives = 75/189 (39%), Gaps = 32/189 (16%)
Query: 258 EGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKD----------E 307
EG + + +E E E A + ++ E A +GE + +D +
Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQ 1900
Query: 308 KKEDGKQA-ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGS 366
+ +G +A E + +T+ E + E + +SE + +++ ++ G +
Sbjct: 1901 PESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEV 1960
Query: 367 VSESESESES--------------------GQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
+ E+E E+ G+A+ E E+ E E E + EE +P +
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQP-E 2019
Query: 407 AAGLECKPR 415
+ G+E +P+
Sbjct: 2020 SDGVEAQPK 2028
Score = 31.6 bits (70), Expect = 3.4
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 10/129 (7%)
Query: 291 AGAGLGDGERKTNDKDEKKEDGKQAEN-DSSNDDKTKKSEGDG---DKEEKKEDSEKEAK 346
A GLG G + DE EDG+ ++ + D K ++EGD ++E K +SE A
Sbjct: 1726 AEGGLGPGLSQGPGVDEG-EDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAG 1784
Query: 347 KSSKKRNRKHSG----DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWE 402
+ ++ G ++ +GS E + E+ ++ + + E P E E E
Sbjct: 1785 SELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAP-EAEGE 1843
Query: 403 KPKDAAGLE 411
++ G+E
Sbjct: 1844 AQPESEGVE 1852
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 57.0 bits (136), Expect = 7e-08
Identities = 53/235 (22%), Positives = 98/235 (41%), Gaps = 10/235 (4%)
Query: 175 YKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFD 234
++ D +R++ + + K+ E R K H +E K R+E + + S E G D
Sbjct: 99 HRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERG-ND 157
Query: 235 NLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAG 294
+ L D+ + + + + E +R ++E+ E++ + +++E A
Sbjct: 158 GVCLFRDRLEQLERKRER---------ERKMREQQKEQREQKERERRAEERRKEREARRE 208
Query: 295 LGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNR 354
+ R + K + + GDG K K+E E+ S +
Sbjct: 209 VSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDIS 268
Query: 355 KHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAG 409
S E S +ES S SE + EEE+EE E + E+ + +EEE E+ ++ G
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 323
Score = 48.9 bits (115), Expect = 2e-05
Identities = 78/401 (19%), Positives = 151/401 (37%), Gaps = 83/401 (20%)
Query: 12 RRDKFRRERSDYDRSRERD--------ERRRGDDWNDREWDRGRER---RSRGEYRDYDR 60
R +RRE S DR E D + R + + R+ ++ +E+ R + + R+++R
Sbjct: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHER 122
Query: 61 NRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDV 120
+R R Q + RR+W+ + G G V
Sbjct: 123 RKRHR---------EEQDKARREWERQKRREMAREHSRRERGNDG--------------V 159
Query: 121 HIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFR 180
+ + + ++ + E + + KE ++ E EA + + +
Sbjct: 160 CLFRDRLEQLERKRER--ERKMREQQKEQREQKERERRAEERRKEREARREVSAH----H 213
Query: 181 RQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDI 240
R +D+ K W RS P + R ++ L+ L DI
Sbjct: 214 RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD------LQDI 267
Query: 241 DKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGER 300
++ +++ + G+E + E+EEEEE+ G E S++EE
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEE---EEEEEEEEEGSTSEESEEEE------------ 312
Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
++E+ ++ E S++++ +++S + +EE ED E+E N H
Sbjct: 313 -------EEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE--------NENHLL-- 355
Query: 361 SFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEW 401
V ES + +SG++EE +EE E + E ++
Sbjct: 356 -----VVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDY 391
Score = 36.6 bits (83), Expect = 0.10
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 1 MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDR 60
MGD D + + D+ +E+ E+ E +R + +DR D R+ GE RD+
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDR--DSKRDSLEEGELRDHCM 58
Query: 61 NRRERFSPPRHE--------------LSPPQKRMRRDWDEHSSD 90
R SP R E + PPQ+ R++ H D
Sbjct: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD 102
Score = 33.5 bits (75), Expect = 0.89
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 21/80 (26%)
Query: 11 RRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERF---- 66
R+R++ R+ R RE+ ER R R +R +ER +R E + R RE +
Sbjct: 171 RKRERERKMREQQKEQREQKERER------RAEERRKEREARREVSAHHRTMREDYSDKV 224
Query: 67 -------SPPRHELSPPQKR 79
SPPR PP++R
Sbjct: 225 KASHWSRSPPR----PPRER 240
Score = 30.4 bits (67), Expect = 7.5
Identities = 22/108 (20%), Positives = 42/108 (38%), Gaps = 9/108 (8%)
Query: 299 ERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
E+K + E+K + K+ +N D K ++ +E ++ RN +
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSK---------RDSLEEGELRDHCMEITIRNSPYRR 69
Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
+DS ++ + + Q KE+ EK K K+ K K+
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKE 117
Score = 30.0 bits (66), Expect = 9.8
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 17/100 (17%)
Query: 333 DKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSE--------------SESESESGQ 378
+K+ +KE EK K K + + S DS +EG + + +S + G+
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78
Query: 379 AEEE---KEEAEEALKEKEKPKEEEWEKPKDAAGLECKPR 415
++ K + + KEK +++E K K A ++ K R
Sbjct: 79 EDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKER 118
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 56.6 bits (135), Expect = 1e-07
Identities = 47/187 (25%), Positives = 83/187 (44%), Gaps = 10/187 (5%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQA 315
K + E D E EE++E + + + +A A E + ++ DE ED
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
E D S ++ + + G K K + AK ++ + + +D D+ + + + E
Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVK--AKNVAEDEDEEEDDEDEDDDDDEDDEDDDDE 259
Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKT-----CSLFMRNIAP 430
+ EEE+EE EE +KE +++E K K A E K + + T +LF+ N+
Sbjct: 260 DDE-EEEEEEEEEPVKEAPGKRKKEMAKQK--AAPEAKKQKVEGTEPTTAFNLFVGNLNF 316
Query: 431 NISRAEI 437
N S E+
Sbjct: 317 NKSAPEL 323
Score = 31.6 bits (70), Expect = 3.4
Identities = 17/74 (22%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query: 334 KEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEK 393
K KKEDS++E S++ + + D+ DE + + ++ + E E+ E+ ++
Sbjct: 138 KNAKKEDSDEEEDDDSEE-DEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196
Query: 394 EKPKEEEWEKPKDA 407
+ +EE + ++A
Sbjct: 197 DDDDDEEDDSEEEA 210
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 20/153 (13%)
Query: 263 NDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322
++LRI + E++ E + + S +E GR K K + G++ + +D
Sbjct: 203 SELRIHDLEDDLEMSSDASDASGEEGGRVP--------KAKKKAPLAKGGRKKKKKKGSD 254
Query: 323 DKTKKSEGDGDKEEKKED-------SEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
D+ + DGD E ++ D S +E +S K ++ G DE S S ESE E
Sbjct: 255 DEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEE 314
Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAA 408
EE+KEE E EK+ P +E ++ KD++
Sbjct: 315 K-PPEEDKEEEE----EKKAPTPQEKKRRKDSS 342
Score = 46.2 bits (108), Expect = 1e-04
Identities = 46/160 (28%), Positives = 76/160 (47%), Gaps = 23/160 (14%)
Query: 263 NDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSND 322
N I++Q ++Q E K++ GR A E + +D ++ E A + S +
Sbjct: 172 NHFSIMQQRRLKDQDQDEDEEEKEKRGRRKAS----ELRIHDLEDDLEMSSDASDASGEE 227
Query: 323 D----KTKKSEG---DGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVS---ESES 372
K KK G K++KK+ S+ EA + S + + D +GS S E ES
Sbjct: 228 GGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPES 287
Query: 373 ESESGQAEE-------EKEEAEEALKEK--EKPKEEEWEK 403
++++ Q EE + + +EE+ +EK E+ KEEE EK
Sbjct: 288 KAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEK 327
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 7/113 (6%)
Query: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSN-DDKTKKSEGDGDKEEKKEDSEKEAK 346
EG+ + DG + ++ E K Q E D+++ SE +++ +ED E+E +
Sbjct: 267 EGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEE 326
Query: 347 KSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEE 399
K + K DS SE SE + E A K+K PK E
Sbjct: 327 KKAPTPQEKKRRKDS------SEESDSSEESDIDSEASSALFMAKKKTPPKRE 373
Score = 40.4 bits (93), Expect = 0.007
Identities = 39/147 (26%), Positives = 57/147 (38%), Gaps = 30/147 (20%)
Query: 270 QEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTK--- 326
QEE E +A P ++EEG G + +D E+ E+ K E D +++ K
Sbjct: 282 QEEPESKAKAP----QQEEGPKGVD------EQSDSSEESEEEKPPEEDKEEEEEKKAPT 331
Query: 327 ---------KSEGDGDKEEKKEDSEKEA------KKSSKKRNRKHSGDDSFDEGSVSESE 371
SE EE DSE + KK+ KR RK SG S G+
Sbjct: 332 PQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSS--RGNSRPGT 389
Query: 372 SESESGQAEEEKEEAEEALKEKEKPKE 398
+E G A L++ ++ E
Sbjct: 390 PSAEGGSTSSTLRAAASKLEQGKRVSE 416
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 56.2 bits (134), Expect = 1e-07
Identities = 39/165 (23%), Positives = 85/165 (51%), Gaps = 21/165 (12%)
Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
V+ + V + EG E + ++ EQE E+EEQ G+ E +K+E + G E++
Sbjct: 173 VREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG------EQE 226
Query: 302 TNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDS 361
+ ++++ G+Q E +++ +K E K+E++ ++E + +++ K
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK---- 282
Query: 362 FDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
++E E ++G+ EE+ E EE ++E+E+ E+ E+ ++
Sbjct: 283 ------EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Score = 51.6 bits (122), Expect = 3e-06
Identities = 39/170 (22%), Positives = 84/170 (49%), Gaps = 10/170 (5%)
Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGD-GER 300
V+ + V + EG E + ++ EQE E+E Q + +++EG+ G G GE+
Sbjct: 145 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204
Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
+ +++++ KQ E +++ +K E ++E++ ++E + +++ RK
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 361 SFDEGSVSESESE----SESGQAEEEKEEAEEALKEKEKPKEEEWEKPKD 406
E + E E + E + EE+ E EE ++E+E+ E+ E+ ++
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/150 (23%), Positives = 73/150 (48%), Gaps = 24/150 (16%)
Query: 262 ENDLRILEQEEE----EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAEN 317
E + ++ EQEE+ EEQ G+ E +K+E + G +++++ KQ E
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMG-------------EQEEQVQKQEEQ 249
Query: 318 DSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESG 377
+++ +K E ++ ++E+ +E ++ K+ + ++ E E E +
Sbjct: 250 VQKQEEQMRKQE---EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 378 QAEEEKEEAEEALKEKE----KPKEEEWEK 403
+ EE+ E EE ++E+E K +E+ WE+
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Score = 47.4 bits (111), Expect = 6e-05
Identities = 34/161 (21%), Positives = 78/161 (48%), Gaps = 20/161 (12%)
Query: 256 KMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKED---- 311
+M E L+ EQ E+EEQ G+ E +++E + + + E + +++E+ +
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ----MREQEEQMREQEEQMREQEEQ 325
Query: 312 -GKQAEND--------SSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSF 362
GKQ E + K+ E G++EE+ + E++ +K ++ ++ ++
Sbjct: 326 MGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ---EEQM 382
Query: 363 DEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
+ + E + G+ +E+ E +E ++E+E+ E+ E+
Sbjct: 383 RKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ 423
Score = 45.4 bits (106), Expect = 2e-04
Identities = 33/147 (22%), Positives = 73/147 (49%), Gaps = 5/147 (3%)
Query: 259 GGTENDLRILEQE--EEEEQAGKPGEPSKKEEGRAGAGLGD-GERKTNDKDEKKEDGKQA 315
G E +R E++ E+EEQ + E +++E + G E+K ++K++ KQ
Sbjct: 292 GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
Query: 316 ENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESE 375
E +++ +K E K+E++ ++E + +++ RK ++ E E + +
Sbjct: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ--EEQMGEQKEQMGEQKEQ 409
Query: 376 SGQAEEEKEEAEEALKEKEKPKEEEWE 402
+ EE+ E +E ++++E+ E+ E
Sbjct: 410 MREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/140 (22%), Positives = 66/140 (47%), Gaps = 18/140 (12%)
Query: 269 EQEEE----EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS-SNDD 323
EQEE+ EEQ G+ E +K+E + ++ E++E ++ E +
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
Query: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
+T++ E G++EE+ + E++ ++ ++ E E E + G+ EE+
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQ----------EEQMREQEEQMREQEEQMGKQEEQM 333
Query: 384 EEAEEALKEKEKPKEEEWEK 403
E +E + E+ KE+ W++
Sbjct: 334 WEQKEQMWEQ---KEQMWKQ 350
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/141 (19%), Positives = 67/141 (47%), Gaps = 2/141 (1%)
Query: 262 ENDLRILEQE--EEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDS 319
E +R E++ E+EEQ + E K++ + GE++ ++++++ +Q E
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR 313
Query: 320 SNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQA 379
+++ ++ E K+E++ +KE K++ K E + + E + +
Sbjct: 314 EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373
Query: 380 EEEKEEAEEALKEKEKPKEEE 400
+ K+E + +E++ K+EE
Sbjct: 374 QMRKQEEQMRKQEEQMRKQEE 394
Score = 40.8 bits (94), Expect = 0.006
Identities = 33/165 (20%), Positives = 80/165 (48%), Gaps = 12/165 (7%)
Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
V+ + V + EG E + ++ EQE E+E Q + +++EG+ +G+ +
Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVR 132
Query: 302 TNDKDEKKEDGKQAENDSS---NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
+ ++++G+ E + + + ++ EG ++E + ++ + + + R+ G
Sbjct: 133 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 192
Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
EG + E E + G+ EE+ ++ EE + E+E+ ++ E+
Sbjct: 193 QMGEQEGQMG--EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235
Score = 40.4 bits (93), Expect = 0.007
Identities = 35/166 (21%), Positives = 78/166 (46%), Gaps = 12/166 (7%)
Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGD-GER 300
V+ + V + EG E + ++ EQE E+E Q + +++EG+ G E+
Sbjct: 124 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
Query: 301 KTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDD 360
+ ++++ + G+Q +++ + E K+E++ ++E + +++ +
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 361 SFDEGSVSESE------SESESGQAEEEKEEAEEALKEKEKPKEEE 400
E V + E E Q E+ +E+ E+ LK+KE+ ++EE
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289
Score = 39.7 bits (91), Expect = 0.012
Identities = 31/156 (19%), Positives = 73/156 (46%), Gaps = 24/156 (15%)
Query: 269 EQEEE----EEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDK 324
EQEE+ EEQ K E +K+E + E++ ++++++ KQ E +
Sbjct: 238 EQEEQVQKQEEQVQKQEEQMRKQEEQMR------EQEEQMREQEEQMLKQKEQTEQEEQT 291
Query: 325 TKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESE-----------SE 373
++ E ++EE+ + E++ ++ ++ + +E + E E
Sbjct: 292 GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE 351
Query: 374 SESGQAEEEKEEAEEALKEKE---KPKEEEWEKPKD 406
+ G+ EE+ ++ EE ++++E + +EE+ K ++
Sbjct: 352 EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
Score = 37.7 bits (86), Expect = 0.047
Identities = 31/170 (18%), Positives = 80/170 (47%), Gaps = 15/170 (8%)
Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
V+ + V + EG E + ++ EQE E+E Q + +++EG+ +G+ +
Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVR 167
Query: 302 TNDKDEKKEDGKQAENDSS---NDDKTKKSEGDGDKE-----EKKEDSEKEAKKSSKKRN 353
+ ++++G+ E + + + + EG ++ E++E +K+ ++ ++
Sbjct: 168 EQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE 227
Query: 354 RKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEK 403
+ ++ E + E + + EE+ + EE ++E+E+ E+ E+
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ 277
Score = 35.8 bits (81), Expect = 0.18
Identities = 31/163 (19%), Positives = 80/163 (49%), Gaps = 13/163 (7%)
Query: 247 VKMLDAAVIKMEGGT-ENDLRILEQE----EEEEQAGKPGEPSKKEEGRAGAGLGDGERK 301
V+ + V + EG E + ++ EQE E+E Q + +++EG+ +G+ +
Sbjct: 103 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ--EGQVR 160
Query: 302 TNDKDEKKEDGKQAENDSS---NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358
+ ++++G+ E + + + ++ EG ++E + ++E +++ +K
Sbjct: 161 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ-- 218
Query: 359 DDSFDEGSVSESESESESGQAEEEKEEAEE-ALKEKEKPKEEE 400
++ E + E + G+ EE+ ++ EE K++E+ +++E
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Score = 32.7 bits (73), Expect = 1.5
Identities = 29/156 (18%), Positives = 70/156 (44%), Gaps = 9/156 (5%)
Query: 262 ENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSS- 320
+ +L+++E E+ E Q K E + +G+ + + ++++G+ E +
Sbjct: 17 QEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ-EGQVREQEGQVREQEGQVREQEGQV 75
Query: 321 --NDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESE--SES 376
+ + ++ EG ++E + ++ + + + R+ G EG V E E + +
Sbjct: 76 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 135
Query: 377 GQAEEEK---EEAEEALKEKEKPKEEEWEKPKDAAG 409
GQ E++ E E ++E+E E+ + ++ G
Sbjct: 136 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,668,440
Number of Sequences: 37866
Number of extensions: 2714715
Number of successful extensions: 45601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 781
Number of HSP's successfully gapped in prelim test: 1234
Number of HSP's that attempted gapping in prelim test: 15779
Number of HSP's gapped (non-prelim): 16054
length of query: 876
length of database: 18,247,518
effective HSP length: 111
effective length of query: 765
effective length of database: 14,044,392
effective search space: 10743959880
effective search space used: 10743959880
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.