Search of human proteins with 58219004

Search of human proteins with 58219004

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58219004 PRAME family member 6 [Homo sapiens]
         (476 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58219004 PRAME family member 6 [Homo sapiens]                      974   0.0  
gi|61696142 PRAME family member 5 [Homo sapiens]                      970   0.0  
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         965   0.0  
gi|148356236 PRAME family member 15 [Homo sapiens]                    939   0.0  
gi|61102721 PRAME family member 9 [Homo sapiens]                      939   0.0  
gi|59958373 PRAME family member 4 [Homo sapiens]                      931   0.0  
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         922   0.0  
gi|226437621 PRAME family member 11 [Homo sapiens]                    852   0.0  
gi|153792112 PRAME family member 20 [Homo sapiens]                    790   0.0  
gi|153945800 PRAME family member 21 [Homo sapiens]                    790   0.0  
gi|88942379 PREDICTED: PRAME family member [Homo sapiens]             756   0.0  
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    660   0.0  
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   585   e-167
gi|59676593 PRAME family member 7 [Homo sapiens]                      583   e-167
gi|59676587 PRAME family member 8 [Homo sapiens]                      583   e-166
gi|124249372 PRAME family member 12 [Homo sapiens]                    575   e-164
gi|46249373 preferentially expressed antigen in melanoma [Homo s...   444   e-124
gi|46249371 preferentially expressed antigen in melanoma [Homo s...   444   e-124
gi|46249369 preferentially expressed antigen in melanoma [Homo s...   444   e-124
gi|46249367 preferentially expressed antigen in melanoma [Homo s...   444   e-124
gi|5174641 preferentially expressed antigen in melanoma [Homo sa...   444   e-124
gi|154800493 PRAME family member 22 [Homo sapiens]                    421   e-118
gi|153791443 PRAME family member 18 [Homo sapiens]                    416   e-116
gi|194306638 PRAME family member 3 [Homo sapiens]                     415   e-116
gi|194306635 PRAME family member 19 [Homo sapiens]                    412   e-115
gi|113865933 PRAME family member 16 [Homo sapiens]                    410   e-114
gi|66954681 PRAME family member 13 [Homo sapiens]                     410   e-114
gi|12738831 PRAME family member 1 [Homo sapiens]                      409   e-114
gi|157426839 PRAME family member 17 [Homo sapiens]                    408   e-114
gi|194018546 PRAME family member 10 [Homo sapiens]                    404   e-113

>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  974 bits (2518), Expect = 0.0
 Identities = 476/476 (100%), Positives = 476/476 (100%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  970 bits (2507), Expect = 0.0
 Identities = 474/476 (99%), Positives = 474/476 (99%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A GCFLNAKRNK PVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  965 bits (2494), Expect = 0.0
 Identities = 472/476 (99%), Positives = 472/476 (99%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A GCFLNAKRNK PVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GIIDSQVNAILPALS CFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           DADGTLCWSRF QIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476


>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  939 bits (2427), Expect = 0.0
 Identities = 464/476 (97%), Positives = 465/476 (97%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A GCFLNAKRNK PVQDCPRMRG+QPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLLHL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
            ADGTLCWSRFAQIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  939 bits (2427), Expect = 0.0
 Identities = 464/476 (97%), Positives = 465/476 (97%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A GCFLNAKRNK PVQDCPRMRG+QPLTVFVELWLKNRTLDEYLT LLLWVKQRKDLLHL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
            ADGTLCWSRFAQIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  931 bits (2406), Expect = 0.0
 Identities = 458/476 (96%), Positives = 462/476 (97%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSI TPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ+WP
Sbjct: 3   MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           FRRLPLRPLIKMPCLEAFQAVLDGLDALL  GV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A GCFLNAKRNK PV+DCPRMRG+QPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKL+LS
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLK LT
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCVELYPAPRESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
            ADGTLCWSRFAQIRAELM RVRDLRHPKRILFCTD CPDCGNRSFYDLEADQ CC
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  922 bits (2384), Expect = 0.0
 Identities = 454/476 (95%), Positives = 463/476 (97%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIR PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 38  MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 98  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A GCFLNAKRNKTPVQDCPRMR +QPLTVFVELWLKNRTLDEYLTCLLLWVKQR+DLLHL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKLVLS
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAP+ESY
Sbjct: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
            ADGTLCWSRFAQIRAELMK+VR LRHPKRILFCTD CPD G+RSFYDLEADQ CC
Sbjct: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513


>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  852 bits (2202), Expect = 0.0
 Identities = 417/436 (95%), Positives = 425/436 (97%)

Query: 41  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKL 100
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKL
Sbjct: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60

Query: 101 QVLDLQDVCENFWMVWSEAMARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTL 160
           QVLDLQDVCENFWMVWSEAMA GCFLNAKRNKTPVQDCPRMR +QPLTVFVELWLKNRTL
Sbjct: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120

Query: 161 DEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 220
           DEYLTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180

Query: 221 LTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSF 280
           LTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240

Query: 281 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 340
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300

Query: 341 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLS 400
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLS
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360

Query: 401 HTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPD 460
           HTIILKNLC+ELYPAP+ESY ADGTLCWSRFAQIRAELMK+VR LRHPKRILFCTD CPD
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420

Query: 461 CGNRSFYDLEADQCCC 476
            G+RSFYDLEADQ CC
Sbjct: 421 HGDRSFYDLEADQYCC 436


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  790 bits (2039), Expect = 0.0
 Identities = 392/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F RLPL  L+K PC E FQAVLDGLDALLT  V  RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           AR C  NA  N+ PVQDCPRMRGQQPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
            +D SRY+SPEQKKE VTQFTTQFLKL CLQKL MNSVSFLEGHLDQ+LSCLKTSL +L 
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GI+DSQVNAILPALSRCFEL TFSF GNPIS ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           D  G +C SRFAQ+ AELM RVR LR P+RILFCTD CP CGNRS YDLE D+CCC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  790 bits (2039), Expect = 0.0
 Identities = 392/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F RLPL  L+K PC E FQAVLDGLDALLT  V  RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           AR C  NA  N+ PVQDCPRMRGQQPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
            +D SRY+SPEQKKE VTQFTTQFLKL CLQKL MNSVSFLEGHLDQ+LSCLKTSL +L 
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GI+DSQVNAILPALSRCFEL TFSF GNPIS ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           D  G +C SRFAQ+ AELM RVR LR P+RILFCTD CP CGNRS YDLE D+CCC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475


>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
          Length = 395

 Score =  756 bits (1952), Expect = 0.0
 Identities = 370/381 (97%), Positives = 373/381 (97%)

Query: 96  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWL 155
           RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNK PVQDCPRMRG+QPLTVFVELWL
Sbjct: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74

Query: 156 KNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 215
           KNRTLDE+LTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134

Query: 216 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSM 275
           WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL M
Sbjct: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194

Query: 276 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 335
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254

Query: 336 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 395
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL
Sbjct: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314

Query: 396 ENLLSHTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCT 455
           ENLLSHTIILKNLC+ELYPAPRESY ADGTLCWSRF QIRAELMKRVRDLRHPKRILF T
Sbjct: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374

Query: 456 DCCPDCGNRSFYDLEADQCCC 476
           D CPDCGNRSFYDLEADQ CC
Sbjct: 375 DYCPDCGNRSFYDLEADQYCC 395


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  660 bits (1703), Expect = 0.0
 Identities = 342/477 (71%), Positives = 382/477 (80%), Gaps = 4/477 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRR KLQVL+L+DV ENFW +WS A 
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
              C   A   +  V+DCPR   +QPL VF+++ LK + +DE L+    WV+ R+  +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   I+ +F+PYL  MRNL+KL +
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239

Query: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
           S  D  RY+     +E +  FTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297

Query: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
           TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357

Query: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
           CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417

Query: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           Y ADGTLCWSRF QIRAELMKRVRDLRHPKRILF TD CPDCGNRSFYDLEADQ CC
Sbjct: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  585 bits (1507), Expect = e-167
 Identities = 300/476 (63%), Positives = 359/476 (75%), Gaps = 2/476 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F RLPL  L+K P LE+ ++VL+G+D LLTQ V PR+ KLQVLDL++V ENF  ++S A 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A   F  A   K    +CP    QQP  VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCK+L++ GMP  +I  +L MV LDCIQEVEV C W L  L +F PYLG MRNL+KLVL 
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           ++  S  + P+ K + + +FT+QFLKL   Q LSM+SVSFLEGHLDQLL CL+ SL+++ 
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  PL  LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           D  G LCW RFA++ AELMK +RDLR PK I+FCT  CP CG R+ YDLE   C C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  583 bits (1504), Expect = e-167
 Identities = 300/476 (63%), Positives = 358/476 (75%), Gaps = 2/476 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F RLPL  L+K P LE+ ++VL+G+D LLTQ V PR+ KLQVLDL++V ENF  ++S A 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A   F  A   K    +CP    QQP  VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCK+L++ GMP  +I  +L MV LDCIQEVEV C W L  L +F PYLG MRNL+KLVL 
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           ++  S  + P+ K + + +FT+QFLKL   Q LSM+SVSFLEGHLDQLL CL+ SL+++ 
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  PL  LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           D  G LCW RFA++ AELMK  RDLR PK I+FCT  CP CG R+ YDLE   C C
Sbjct: 419 DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  583 bits (1503), Expect = e-166
 Identities = 299/476 (62%), Positives = 359/476 (75%), Gaps = 2/476 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSIR PPRLLELA + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F RLPL  L+K P LE+ ++VL+G+D LLTQ V PR+ KLQVLDL++V ENF  ++S A 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A   F  A   K    +CP    QQP  VF++L LKNRTLDE LT LL W KQRK LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CC++L++ GMP  +I  +L MV LDCIQEVEV C W L  L +F PYLG MRNL+KLVL 
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           ++  S  + P+ K + + +FT+QFLKL   Q LSM+SVSFLEGHLDQLL CL+ SL+++ 
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  PL  LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
           D  G LCW RFA++ AELMK +RDLR PK I+FCT  CP CG R+ YDLE   C C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  575 bits (1481), Expect = e-164
 Identities = 300/480 (62%), Positives = 355/480 (73%), Gaps = 6/480 (1%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS++ PPRLLELA +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L  MVQAWP
Sbjct: 1   MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K   LE F+AVL+GLDALL Q V PRRWKLQVLDL++V ENFW +WS A 
Sbjct: 61  FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A      +KR      +CPR  GQQPL V ++L  KN  LDE LT  L W KQRK LLH+
Sbjct: 121 ALSPEALSKRRTAG--NCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CCK+L+I G+    I  +L  V LDCIQEVEV C W L IL +F PYLG MRNL+KLVL 
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238

Query: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
           ++ VS  +  ++K++ V QFT+QFLKL   QKL M+SVSFLEGHLDQLL CL+  L+ + 
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298

Query: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
           +T C+L ESDLKHLS CPSI QLK LDL GI LT++S  PL +LLE+  ATL+ LDL+DC
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358

Query: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
           GI+DSQ++AILPALSRC +L+TFSFCGN ISMA LENLL HT+ L  L +ELYPAP ESY
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418

Query: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC----CC 476
           DA G LCW RF+Q+ AELMK +RDLR PK I+F T  CP CG R+ YDLE   C    CC
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478


>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  444 bits (1141), Expect = e-124
 Identities = 246/489 (50%), Positives = 321/489 (65%), Gaps = 13/489 (2%)

Query: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76

Query: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136

Query: 117 SEAMARGCFLNAKRNKTPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168
           S   A            P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196

Query: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256

Query: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316

Query: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376

Query: 349 AATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNL 408
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436

Query: 409 CVELYPAPRESY-DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467
              LYP P ESY D  GTL   R A + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496

Query: 468 DLEADQCCC 476
           D E   C C
Sbjct: 497 DPEPILCPC 505


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  444 bits (1141), Expect = e-124
 Identities = 246/489 (50%), Positives = 321/489 (65%), Gaps = 13/489 (2%)

Query: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76

Query: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136

Query: 117 SEAMARGCFLNAKRNKTPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168
           S   A            P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196

Query: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256

Query: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316

Query: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376

Query: 349 AATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNL 408
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436

Query: 409 CVELYPAPRESY-DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467
              LYP P ESY D  GTL   R A + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496

Query: 468 DLEADQCCC 476
           D E   C C
Sbjct: 497 DPEPILCPC 505


>gi|46249369 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  444 bits (1141), Expect = e-124
 Identities = 246/489 (50%), Positives = 321/489 (65%), Gaps = 13/489 (2%)

Query: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76

Query: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136

Query: 117 SEAMARGCFLNAKRNKTPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168
           S   A            P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196

Query: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256

Query: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316

Query: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376

Query: 349 AATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNL 408
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436

Query: 409 CVELYPAPRESY-DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467
              LYP P ESY D  GTL   R A + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496

Query: 468 DLEADQCCC 476
           D E   C C
Sbjct: 497 DPEPILCPC 505


>gi|46249367 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  444 bits (1141), Expect = e-124
 Identities = 246/489 (50%), Positives = 321/489 (65%), Gaps = 13/489 (2%)

Query: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76

Query: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136

Query: 117 SEAMARGCFLNAKRNKTPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168
           S   A            P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196

Query: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256

Query: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316

Query: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376

Query: 349 AATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNL 408
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436

Query: 409 CVELYPAPRESY-DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467
              LYP P ESY D  GTL   R A + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496

Query: 468 DLEADQCCC 476
           D E   C C
Sbjct: 497 DPEPILCPC 505


>gi|5174641 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  444 bits (1141), Expect = e-124
 Identities = 246/489 (50%), Positives = 321/489 (65%), Gaps = 13/489 (2%)

Query: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76

Query: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136

Query: 117 SEAMARGCFLNAKRNKTPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168
           S   A            P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196

Query: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256

Query: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316

Query: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376

Query: 349 AATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNL 408
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436

Query: 409 CVELYPAPRESY-DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467
              LYP P ESY D  GTL   R A + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496

Query: 468 DLEADQCCC 476
           D E   C C
Sbjct: 497 DPEPILCPC 505


>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  421 bits (1083), Expect = e-118
 Identities = 238/476 (50%), Positives = 310/476 (65%), Gaps = 5/476 (1%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+L+DV ENFW +WS A 
Sbjct: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
              C   A   +  V+DCPR   +QPL VF+++ LK + +DE L+    WV+ R+  +HL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F+ YL  MRNL+KL +
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241

Query: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
           S  D  RY +S + ++++V +F++  L+L  LQ L +  V F  GHLDQL+ CL++ L+ 
Sbjct: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299

Query: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
           L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359

Query: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
           DCGI DS++  ILPALS C  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419

Query: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
           S D  G +       ++AELM+ +R++R PKRI F    CP CG      LE + C
Sbjct: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  416 bits (1069), Expect = e-116
 Identities = 238/476 (50%), Positives = 308/476 (64%), Gaps = 5/476 (1%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
              C   A   +  V+DCPR   +QPL VF+++ LK +++DE L+    WV+ R+  +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239

Query: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
           S  D   Y+ S E + ++V +F++ FL+L  LQ L M  + F EG+LDQL+ CLK+ L+ 
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297

Query: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357

Query: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
           DCGI DS++  ILPALSRC  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 358 DCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417

Query: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
           S D  G +       ++AELM+ +R++R P RI F    CP CG      LE + C
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  415 bits (1067), Expect = e-116
 Identities = 237/476 (49%), Positives = 308/476 (64%), Gaps = 5/476 (1%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRR KLQVL+L+DV ENFW +WS A 
Sbjct: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
              C   A   +  V+DCPR   +QPL VF+++ LK + +DE L+    WV+ R+  +HL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ +F  YL  MRNL+KL +
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFIRYLSQMRNLRKLFI 241

Query: 240 SHMDVSRY-VSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
           S  D  RY +S + ++++V +F++  L+L  LQ L +  V F  GHLDQL+ CL++ L+ 
Sbjct: 242 S--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLET 299

Query: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
           L +T   L + DLK L + PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 300 LALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLV 359

Query: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
           DCGI DS++  ILPALS C  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 360 DCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 419

Query: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
           S D  G +       ++AELM+ +R++R PKRI F    CP CG      LE + C
Sbjct: 420 SLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475


>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  412 bits (1060), Expect = e-115
 Identities = 237/476 (49%), Positives = 307/476 (64%), Gaps = 5/476 (1%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
              C   A   +  V+DCPR   +QPL VF+++ LK +++DE L+    WV+ R+  +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239

Query: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
           S  D   Y+ S E + ++V +F++ FL+L  LQ L M  + F EG+LDQL+ CLK+ L+ 
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297

Query: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357

Query: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
           DCGI  S++  ILPALSRC  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417

Query: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
           S D  G +       ++AELM+ +R++R P RI F    CP CG      LE + C
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  410 bits (1054), Expect = e-114
 Identities = 235/464 (50%), Positives = 291/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F RLPL  L+K P LE  QAVL GLD LL Q + PRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A  C   A R +  V+D PR    QPL VF++L  K  TLDE L+ L  W+  R+ L+HL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
              D   YVS +Q  + V      FL L   Q L +  +S ++ HL+ LL CLK  L   
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298

Query: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358

Query: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
           C I DSQ+  +LPALSRC +L TF F GN  S   L++LL HT  L  L +ELYPAP E 
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418

Query: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
            D  G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  410 bits (1054), Expect = e-114
 Identities = 232/476 (48%), Positives = 303/476 (63%), Gaps = 3/476 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSI+ PPRLLELAG+SLLRDQAL++S +EELP  L+ PLFMEAF RR  + L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K   LE  +A+L+GL  LLTQ   PRRWKLQVLDL+DV ENFW  W  A 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A  CF      +   +DCPRM   QPL VF+++ LK    DE L  L  WV QR+ L+HL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
           CC KL     P +++R  LK++ L+ IQ++E+ N  W   ++ +   YL  M+NL+KLV 
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239

Query: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
           S    S     E +  +VT+F++ FL+L  LQ L +  ++F  GHL+QL+ CL+  L+ L
Sbjct: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298

Query: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
            +T   LLE D+K LSQ PS+  LK L+LS + L   SL PL  LLEK+AA+LE L L+ 
Sbjct: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358

Query: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
           C I  SQ++AILP LS C +L TF F  N +SM  L++LL HT  L  L +E YPAP ES
Sbjct: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418

Query: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
            ++   + W  FA +RAELM  +R++R PKRI      CP CG+    +LE   CC
Sbjct: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  409 bits (1051), Expect = e-114
 Identities = 233/477 (48%), Positives = 304/477 (63%), Gaps = 5/477 (1%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MSI+ PPRLLELAG+SLLRDQAL++S +EELP  L+ PLFMEAFSRR  + L +MVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K   LE  +A+L+GL  LLTQ   PRRWKLQVLDL+DV ENFW  W  A 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A  CF      +   +DCPRM   QPL VF+++ LK    DE L  L  WV QR+ L+HL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
           CC KL     P + +R  LK++ L+ IQE+E+ N  W   ++ +   YL  M+NL+KLV 
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239

Query: 240 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
           S      Y S  E +  +V +F++ FL+L  LQ L +  ++F  GHL+QL+ CL+  L+ 
Sbjct: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297

Query: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
           L +T   LLE D+K LSQ PS+  LK L+LS + L   SL PL  LLEK+AA+L+ L L+
Sbjct: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357

Query: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
            C I  SQ++AILPALSRC +L TF F  N +S+  L++LL HT  L  L +E YPAP E
Sbjct: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417

Query: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCC 475
           S ++   + W  F  +RAELM  +R++R PKRI      CP CG+    +LE   CC
Sbjct: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474


>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  408 bits (1048), Expect = e-114
 Identities = 234/464 (50%), Positives = 290/464 (62%), Gaps = 3/464 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS+++P RLLELAG+SLLR+Q L +  L+ELP E+FP +FMEA S R  EALKLMVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F RLPL  L+K P LE  QAVL GLD LL Q + PRRWKLQVLDL+DV  NFW +WS A 
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
           A  C   A   +  V+D PR    QPL VF++L  K  TLDE L+ L  W+  R+ L+HL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CC K++   MP  + R++LK V  D IQE+E+  K  L    +F PYL  M NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
              D   YVS +Q  + V      FL L   Q L +  +S ++ HL+ LL CLK  L   
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298

Query: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
              +  L + D++ LSQ PS+SQLK L L  I +   +L PL  LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358

Query: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
           C I DSQ+  +LPALSRC +L TF F GN  S   L++LL HT  L  L +ELYPAP E 
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418

Query: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
            D  G + W   A IRAELM  +R++R PKRI F    CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  404 bits (1039), Expect = e-113
 Identities = 230/464 (49%), Positives = 294/464 (63%), Gaps = 3/464 (0%)

Query: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
           MS++ P RLLELAG+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
           F  LPL  L+K   LE  QAVL GLD L+ Q V PRRWKLQVLDL+DV ENFW +WS A 
Sbjct: 61  FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
              C   A   +  V+DCPRM   QPL VF++L LK  TLDE L+ L  W+  R+ L+HL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
           CC K++   MP  + R++L+ +  D IQE+EV  K  L    +F PYL  M NL++L L+
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240

Query: 241 H-MDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
              +   YVS +     +    + FL L   Q L +  +S ++ HL+ LL  LK  L   
Sbjct: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298

Query: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
             ++  L + D++ LSQ PS+SQLK L L  I +    L PL +LLEKVAATL+ L L D
Sbjct: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358

Query: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
           C I D Q+  +LPALS C +L TF+F GN  SM  L++LL HT  L  L +ELYPAP ES
Sbjct: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418

Query: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGN 463
            D  G + W     IRAELM+ +R++R PKRI F    CP+CG+
Sbjct: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,957,115
Number of Sequences: 37866
Number of extensions: 769017
Number of successful extensions: 2207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2076
Number of HSP's gapped (non-prelim): 106
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.