Search of human proteins with 58082049

Search of human proteins with 58082049

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58082049 acyl-CoA synthetase medium-chain family member 2A
[Homo sapiens]
         (577 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...  1176   0.0  
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...  1151   0.0  
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...  1151   0.0  
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...  1079   0.0  
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...  1079   0.0  
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...   683   0.0  
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...   666   0.0  
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...   652   0.0  
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...   649   0.0  
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s...   399   e-111
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...   378   e-105
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom...   162   8e-40
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom...   159   5e-39
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo...   153   5e-37
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso...   152   1e-36
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]       123   4e-28
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]       123   4e-28
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]       113   5e-25
gi|38524616 solute carrier family 27, member 1 [Homo sapiens]          99   8e-21
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           78   3e-14
gi|40807357 solute carrier family 27 (fatty acid transporter), m...    77   3e-14
gi|227499619 solute carrier family 27 (fatty acid transporter), ...    61   3e-09
gi|62865631 solute carrier family 27 (fatty acid transporter), m...    60   5e-09
gi|13325055 solute carrier family 27 (fatty acid transporter), m...    60   5e-09
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo...    60   7e-09
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo...    60   7e-09
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo...    60   7e-09
gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]          58   3e-08
gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-ch...    58   3e-08
gi|239745482 PREDICTED: hypothetical protein [Homo sapiens]            58   3e-08

>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score = 1176 bits (3043), Expect = 0.0
 Identities = 577/577 (100%), Positives = 577/577 (100%)

Query: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60
           MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA
Sbjct: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60

Query: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW 120
           GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW
Sbjct: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW 120

Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180
           LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK
Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180

Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240
           LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL
Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240

Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL 300
           KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL
Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL 300

Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES 360
           SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES
Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES 360

Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420
           YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI
Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420

Query: 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480
           GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN
Sbjct: 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480

Query: 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540
           ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY
Sbjct: 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540

Query: 541 PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ 577
           PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ
Sbjct: 541 PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ 577


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 1151 bits (2977), Expect = 0.0
 Identities = 562/577 (97%), Positives = 570/577 (98%)

Query: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60
           MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA
Sbjct: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60

Query: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW 120
           GKRLPSPALWWVNGKGKELMWNFRELSENSQQAAN+LSGACGLQRGDRVAV+LPRVPEWW
Sbjct: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWW 120

Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180
           LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK
Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180

Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240
           LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL
Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240

Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL 300
           KAKMDAGWTGLQASDIMWTISDTGWILNIL SL+E W LGACTFVHLLPKFDPLVILKTL
Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300

Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES 360
           SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNC+  GESLLPETLENWRAQTGLDIRE 
Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360

Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420
           YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQ+IDDKGNVLPPGTEGDIGIRVKPIRPI
Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPI 420

Query: 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480
           GIFSGYV+NPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN
Sbjct: 421 GIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480

Query: 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540
           ALM+HPAVVETAVISSPDPVRGEVVKAFV+LASQFLSHDPEQLTKELQQHVKSVTAPYKY
Sbjct: 481 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 540

Query: 541 PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ 577
           PRKIEFVLNLPKTVTGKIQR KLRDKEWKMSGKARAQ
Sbjct: 541 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 577


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score = 1151 bits (2977), Expect = 0.0
 Identities = 562/577 (97%), Positives = 570/577 (98%)

Query: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60
           MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA
Sbjct: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60

Query: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW 120
           GKRLPSPALWWVNGKGKELMWNFRELSENSQQAAN+LSGACGLQRGDRVAV+LPRVPEWW
Sbjct: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWW 120

Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180
           LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK
Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180

Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240
           LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL
Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240

Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL 300
           KAKMDAGWTGLQASDIMWTISDTGWILNIL SL+E W LGACTFVHLLPKFDPLVILKTL
Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300

Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES 360
           SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNC+  GESLLPETLENWRAQTGLDIRE 
Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360

Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420
           YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQ+IDDKGNVLPPGTEGDIGIRVKPIRPI
Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPI 420

Query: 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480
           GIFSGYV+NPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN
Sbjct: 421 GIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480

Query: 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540
           ALM+HPAVVETAVISSPDPVRGEVVKAFV+LASQFLSHDPEQLTKELQQHVKSVTAPYKY
Sbjct: 481 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 540

Query: 541 PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ 577
           PRKIEFVLNLPKTVTGKIQR KLRDKEWKMSGKARAQ
Sbjct: 541 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 577


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 537/577 (93%), Positives = 546/577 (94%), Gaps = 6/577 (1%)

Query: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60
           MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA
Sbjct: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60

Query: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW 120
           GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAV+LPRVPEWW
Sbjct: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120

Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180
           LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK
Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180

Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240
           LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL
Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240

Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL 300
           KAKMDAGWTGLQASDIMWTISDTGWILNIL SL+E W LGACTFVHLLPKFDPLVILKTL
Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300

Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES 360
           SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNC+  GESLLPETLENWRAQTGLDIRE 
Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360

Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420
           YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQ+I     V      GD+G         
Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI---AFVHGSPRAGDLGFAGTMTLS- 416

Query: 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480
             F G+ +NPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN
Sbjct: 417 --FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 474

Query: 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540
           ALM+HPAVVETAVISSPDPVRGEVVKAFV+LASQFLSHDPEQLTKELQQHVKSVTAPYKY
Sbjct: 475 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 534

Query: 541 PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ 577
           PRKIEFVLNLPKTVTGKIQR KLRDKEWKMSGKARAQ
Sbjct: 535 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 537/577 (93%), Positives = 546/577 (94%), Gaps = 6/577 (1%)

Query: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60
           MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA
Sbjct: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLVSLQWGHQEVPAKFNFASDVLDHWADMEKA 60

Query: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWW 120
           GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAV+LPRVPEWW
Sbjct: 61  GKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWW 120

Query: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180
           LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK
Sbjct: 121 LVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIK 180

Query: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240
           LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL
Sbjct: 181 LLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGL 240

Query: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTL 300
           KAKMDAGWTGLQASDIMWTISDTGWILNIL SL+E W LGACTFVHLLPKFDPLVILKTL
Sbjct: 241 KAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTL 300

Query: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGLDIRES 360
           SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNC+  GESLLPETLENWRAQTGLDIRE 
Sbjct: 301 SSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTGLDIREF 360

Query: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420
           YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQ+I     V      GD+G         
Sbjct: 361 YGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVI---AFVHGSPRAGDLGFAGTMTLS- 416

Query: 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 480
             F G+ +NPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN
Sbjct: 417 --FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVEN 474

Query: 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540
           ALM+HPAVVETAVISSPDPVRGEVVKAFV+LASQFLSHDPEQLTKELQQHVKSVTAPYKY
Sbjct: 475 ALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKY 534

Query: 541 PRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ 577
           PRKIEFVLNLPKTVTGKIQR KLRDKEWKMSGKARAQ
Sbjct: 535 PRKIEFVLNLPKTVTGKIQRTKLRDKEWKMSGKARAQ 571


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score =  683 bits (1762), Expect = 0.0
 Identities = 327/534 (61%), Positives = 406/534 (76%), Gaps = 1/534 (0%)

Query: 37  HQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANV 96
           ++ +P  FNFA+DVLD W+  EK G+R  +PALWWVNGKG E+ W+FREL   S++AANV
Sbjct: 45  NRPLPKNFNFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANV 104

Query: 97  LSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKA 156
           L+  CGLQRGDR+AV+LPR+PEWWLV + CIR G+IFMPGTIQ+ + DILYRL+ SKAK 
Sbjct: 105 LTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKC 164

Query: 157 IVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEAS 216
           IVA +EV   V+++  ECP L+ KLLVS +S +GWL+F++L   AS  H CVETGSQE  
Sbjct: 165 IVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPM 224

Query: 217 AIYFTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILCSLME 275
            IYFTSGT+G PKMA+HS SSLG+   +    W  L++SDI+W +SDTGW+   + S+  
Sbjct: 225 TIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFS 284

Query: 276 PWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCV 335
            W  GAC FVH + +FD    L TL++YPI ++   P VYRML+Q+DL  YKF  L++C+
Sbjct: 285 SWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCL 344

Query: 336 TVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQII 395
           T GE L PE LE WR QTGL++ E YGQTE G+ C   K  +IKPG MG     YDVQII
Sbjct: 345 TGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQII 404

Query: 396 DDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGY 455
           D+ GNVLPPG EG+I +R+KP RP   FS YVDNP KTAA IRGDF++ GDRG+ D DGY
Sbjct: 405 DENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGY 464

Query: 456 FQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQF 515
           F F+GRADD+I SSGYRIGP EVE+AL+EHPAVVE+AV+SSPD +RGEVVKAFVVLA+ F
Sbjct: 465 FWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPF 524

Query: 516 LSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 569
            S++PE+LT ELQ HVK  TAPYKYPRK+EFV  LPKT+TGKI+R  LRD+EW+
Sbjct: 525 KSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWR 578


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score =  666 bits (1719), Expect = 0.0
 Identities = 321/577 (55%), Positives = 422/577 (73%), Gaps = 14/577 (2%)

Query: 1   MHWLRKVQGLCTLWGTQMSSRTLYINSRQLV--------SLQWGHQEVPAKFNFASDVLD 52
           M WL + +   TLWG   S   ++    QL         + +W   EVP +FNFAS VLD
Sbjct: 1   MQWLMRFR---TLWGIHKSFHNIHPAPSQLRCRSLSEFGAPRWNDYEVPEEFNFASYVLD 57

Query: 53  HWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVV 112
           +WA  EK GKR P+PA WWVNG+G E+ W+FRE+ + +++ ANV +  CGLQ+GD +A++
Sbjct: 58  YWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALM 117

Query: 113 LPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVAS 172
           LPRVPEWWLV +GC+R G+IF+P TI +K+ DILYRLQ+SKAK IV  D +  EVD++AS
Sbjct: 118 LPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDSIAS 177

Query: 173 ECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAE 232
           +CPSL+ KLLVS+ S +GWL+F+ L+  AS  H CV++ + +   I+FTSGT+G PKMA+
Sbjct: 178 QCPSLKTKLLVSDHSREGWLDFRSLVKSASPEHTCVKSKTLDPMVIFFTSGTTGFPKMAK 237

Query: 233 HSYSSLGLKAKMDAG--WTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPK 290
           HS+  L L+           L+ SD+ W +SD+GWI+  + +L+EPW  G   F+H LP+
Sbjct: 238 HSHG-LALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAGCTVFIHHLPQ 296

Query: 291 FDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWR 350
           FD  VI++TL  YPI    G   +YRM+LQQD +S +FP L++C T GE +LP+  E W+
Sbjct: 297 FDTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFPALEHCYTGGEVVLPKDQEEWK 356

Query: 351 AQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDI 410
            +TGL + E+YGQ+ETGL C     MKIKPG+MG A   YDVQ+IDDKG++LPP TEG+I
Sbjct: 357 RRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVIDDKGSILPPNTEGNI 416

Query: 411 GIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSG 470
           GIR+KP+RP+ +F  Y  +P+KTA    GDF+  GDRG  DE+GY  F+GR+DDIIN+SG
Sbjct: 417 GIRIKPVRPVSLFMCYEGDPEKTAKVECGDFYNTGDRGKMDEEGYICFLGRSDDIINASG 476

Query: 471 YRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQH 530
           YRIGP+EVE+AL+EHPAV E+AV+ SPDP+RGEVVKAF+VL  QFLSHD +QLTKELQQH
Sbjct: 477 YRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQH 536

Query: 531 VKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKE 567
           VKSVTAPYKYPRK+EFV  LPKT+TGKI+R +LR KE
Sbjct: 537 VKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKKE 573


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score =  652 bits (1682), Expect = 0.0
 Identities = 309/531 (58%), Positives = 384/531 (72%), Gaps = 1/531 (0%)

Query: 40  VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99
           +P  FNFA DVLD W D EKAGK+  +PA WW+N  G+E+ W+F EL   S++ AN+LS 
Sbjct: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113

Query: 100 ACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159
           AC LQRGDRV ++LPRVPEWWL  + C+R G + +PGT Q+   DILYRLQ SKA  I+ 
Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173

Query: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219
            D +   VD VAS+C +L  KL+VSE S +GW N K+L+  AS +H CV+T   E  AI+
Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233

Query: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILCSLMEPWA 278
           FTSGTSG PKM  H++SS GL   ++   W  L  SD+MW  SDTGW  +   S+  PW 
Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293

Query: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVG 338
            GAC F H LP+F+P  IL+TLS YPI     AP VYRML+Q D++SYKF  L++CV+ G
Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353

Query: 339 ESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDK 398
           E + P+  E WR +TGLDI E YGQTET L C   K MKIKPG MG  +  +DV+I+D  
Sbjct: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413

Query: 399 GNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQF 458
           GNVLPPG EGDIGI+V P RP G+F+ YVDNP KTA+ +RG+F++ GDRG  D+DGYF F
Sbjct: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473

Query: 459 MGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSH 518
           + RADD+I SSGYRIGP EVENAL EHP+V E+AV+SSPDP+RGEVVKAFVVL   + SH
Sbjct: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533

Query: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 569
           D EQL KE+Q+HVK  TAPYKYPRK+EF+  LPKT++GK +R +LR KEWK
Sbjct: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWK 584


>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score =  649 bits (1675), Expect = 0.0
 Identities = 306/538 (56%), Positives = 398/538 (73%), Gaps = 2/538 (0%)

Query: 32  SLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQ 91
           ++  G Q VP  FNFA DVLD W+ +E+AG R P+PA WWVNG G E+ W+F EL + S+
Sbjct: 41  AISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSR 100

Query: 92  QAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQM 151
           +AANVL GACGLQ GDR+ +VLPR+PEWWLV + C+R G + +PG  Q+   D+ YRLQ 
Sbjct: 101 KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQA 160

Query: 152 SKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG 211
           S+AK+I+  D +   VD +++ECPSL+ KLLVS+ S  GWLNF++LL EAST H+C+ T 
Sbjct: 161 SRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTK 220

Query: 212 SQEASAIYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNIL 270
           S++  AIYFTSGT+G PKM EHS SS GL        W  L  SDI W  +DTGW+    
Sbjct: 221 SRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWV-KAA 279

Query: 271 CSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPH 330
            +L   W  G+C FVH LP+ D  VIL TLS +PI ++   P ++R+L+Q+DL+ Y+F  
Sbjct: 280 WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQS 339

Query: 331 LQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCY 390
           L++C+T GE+L P+  E W+ QTG+++ E YGQ+ET + C   K MKIK G MG A+  Y
Sbjct: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399

Query: 391 DVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIK 450
           DVQI+DD+GNVLPPG EG++ +R++P RP   F+ Y+DNP+KTAA+ +GDF++ GDR   
Sbjct: 400 DVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARM 459

Query: 451 DEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510
           D+DGYF FMGR DD+INSS YRIGP EVE+AL EHPAV+E+AV+SSPDP+RGEVVKAF+V
Sbjct: 460 DKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIV 519

Query: 511 LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEW 568
           L   + SHDPE LT+ELQ+HVK VTAPYKYPRK+ FV  LPKTV+GKIQR+KLR +EW
Sbjct: 520 LTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577


>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
           sapiens]
          Length = 438

 Score =  399 bits (1026), Expect = e-111
 Identities = 189/356 (53%), Positives = 240/356 (67%), Gaps = 1/356 (0%)

Query: 40  VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99
           +P  FNFA DVLD W D EKAGK+  +PA WW+N  G+E+ W+F EL   S++ AN+LS 
Sbjct: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113

Query: 100 ACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159
           AC LQRGDRV ++LPRVPEWWL  + C+R G + +PGT Q+   DILYRLQ SKA  I+ 
Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173

Query: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219
            D +   VD VAS+C +L  KL+VSE S +GW N K+L+  AS +H CV+T   E  AI+
Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233

Query: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILCSLMEPWA 278
           FTSGTSG PKM  H++SS GL   ++   W  L  SD+MW  SDTGW  +   S+  PW 
Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293

Query: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVG 338
            GAC F H LP+F+P  IL+TLS YPI     AP VYRML+Q D++SYKF  L++CV+ G
Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353

Query: 339 ESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQI 394
           E + P+  E WR +TGLDI E YGQTET L C   K MKIKPG MG  +  +DV++
Sbjct: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score =  378 bits (970), Expect = e-105
 Identities = 189/438 (43%), Positives = 278/438 (63%), Gaps = 2/438 (0%)

Query: 38  QEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVL 97
           Q V   FNFA DVLD W+ +EK G R P PALW V+ KG+E  W+F  +++ S++AA++L
Sbjct: 43  QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102

Query: 98  SGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAI 157
           S  C L  GDR+ ++LP  PE + + L C+R G+ F+PG+ Q+ +  I Y+L+MSKA+ I
Sbjct: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162

Query: 158 VAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA 217
           VA + +   V++  S+CP+L+ KLLVS+KS DGWL+FKKL+  A      + T SQ+  A
Sbjct: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222

Query: 218 IYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNILCSLMEP 276
           I+FT GT+G PKM E+S   LG+  ++    W  LQ +D++W++ D       L +++  
Sbjct: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282

Query: 277 WALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQD-LSSYKFPHLQNCV 335
           W  GAC F+  +P F P  +L  LS +PI ++   P +Y+ LLQ    +SY+F  L+ CV
Sbjct: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342

Query: 336 TVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQII 395
             G  + P  +E+W+  T LDI E YGQTETGL C  SKT+K+KP  +G     Y VQI+
Sbjct: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402

Query: 396 DDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGY 455
           D+  N+LPPG EG+I IR+K  +P  ++  ++ + ++ A+      +L GDRGI DEDGY
Sbjct: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462

Query: 456 FQFMGRADDIINSSGYRI 473
           F + GR DD+ N+ G R+
Sbjct: 463 FWWSGRVDDVANALGQRL 480


>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
           sapiens]
          Length = 689

 Score =  162 bits (410), Expect = 8e-40
 Identities = 148/531 (27%), Positives = 239/531 (45%), Gaps = 45/531 (8%)

Query: 69  LWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIR 128
           +W  +  G E+   +REL E + + AN L    G+ RGDRVA+ +P  P     +L C R
Sbjct: 129 IWERDEPGTEVRITYRELLETTCRLANTLKRH-GVHRGDRVAIYMPVSPLAVAAMLACAR 187

Query: 129 AGLIFMPGTIQMKSTDILYRLQMSKAKAIVA------GDEVIQE---VDTVASECPSLRI 179
            G +         +  +  R+  +K K ++       G  V++    VD     CP+++ 
Sbjct: 188 IGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQH 247

Query: 180 KLLV---SEKSCDGWLNFKKLLNEASTTHHCV--ETGSQEASAIYFTSGTSGLPKMAEHS 234
            L+      K   G L+       A     C     GS++   + +TSG++G+PK   H+
Sbjct: 248 VLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHT 307

Query: 235 ------YSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLL 288
                 Y++L  K   D      Q  DI   ++D GWI      +  P   GA + +   
Sbjct: 308 QAGYLLYAALTHKLVFDH-----QPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFES 362

Query: 289 PKFDPLV--ILKTLSSYPIKSMMGAPIVYRMLLQQD---LSSYKFPHLQNCVTVGESLLP 343
               P      +T+    I    GAP   R+LL+     +  Y    L+   +VGE +  
Sbjct: 363 TPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINC 422

Query: 344 ETLENWRAQTGLDIR----ESYGQTETGLTCMVSKTMK----IKPGYMGTAASCYDVQII 395
           E  E W  +   D R    +++ QTETG  C+  +  +    I P             ++
Sbjct: 423 EAWE-WLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLM 481

Query: 396 DDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRG--DFWLLGDRGIKDED 453
           D+KG+V+  G+     + +    P    + Y D+     A  +    ++  GD   + E 
Sbjct: 482 DEKGSVVE-GSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEG 540

Query: 454 GYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLAS 513
           GY+Q  GR DD+IN SG+R+G +E+E+A+ +HPAV E+AVI  P  ++GE   AF+V+  
Sbjct: 541 GYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKD 600

Query: 514 QFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
              + D + + +EL+  V +  A Y  P +I  V  LPKT +GK+ R  LR
Sbjct: 601 S--AGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLR 649


>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
           sapiens]
          Length = 686

 Score =  159 bits (403), Expect = 5e-39
 Identities = 138/517 (26%), Positives = 224/517 (43%), Gaps = 39/517 (7%)

Query: 81  WNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQM 140
           + ++E+ E   + A VL    G+++GD V + +P +P+    +L C R G I        
Sbjct: 144 FTYKEVLEQVSKLAGVLVKH-GIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGF 202

Query: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNE 200
            S ++  R+   K K +V     I+    V    P +   L + +   D  L + +   E
Sbjct: 203 ASKELSSRIDHVKPKVVVTASFGIEPGRRV-EYVPLVEEALKIGQHKPDKILIYNRPNME 261

Query: 201 A-----------------STTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAK 243
           A                 + +H CV   S+    I +TSGT+GLPK          +   
Sbjct: 262 AVPLAPGRDLDWDEEMAKAQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGGYAVMLH 321

Query: 244 MD-AGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHL---LPKFDPLVILKT 299
              +   GLQ  ++ W  SD GW++        P   G  T ++    +   D     + 
Sbjct: 322 WSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRV 381

Query: 300 LSSYPIKSMMGAPIVYRMLLQQDLSS-----YKFPHLQNCVTVGESLLPETLENWRAQTG 354
           L+ + + ++  AP   R + QQD  +     Y     +     GE    ETLE  +    
Sbjct: 382 LAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVFR 441

Query: 355 LDIRESYGQTETG----LTCM-VSKTMKIKPGYMGTAASCYDVQIIDDKGNVLPPGTEGD 409
           + + + + QTETG     +C+ +  +    PG  G +   Y+V I+DD    L     G+
Sbjct: 442 VPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCLGN 501

Query: 410 IGIRVKPIRPIGIFSGYVDNPDKTAANIRGDF---WLLGDRGIKDEDGYFQFMGRADDII 466
           I +++ P+ P G FSG   N +         F   +   D G  DE+GY   M R DD+I
Sbjct: 502 IVVKL-PLPP-GAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVI 559

Query: 467 NSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKE 526
           N +G+RI    +E +++ H  V + AV+   DP++G V  A  VL    ++   EQ+ +E
Sbjct: 560 NVAGHRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKD-INATEEQVLEE 618

Query: 527 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKL 563
           + +HV+    P    R   FV  LPKT +GKI R+ L
Sbjct: 619 IVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSAL 655


>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
           1 [Homo sapiens]
          Length = 701

 Score =  153 bits (386), Expect = 5e-37
 Identities = 152/587 (25%), Positives = 248/587 (42%), Gaps = 81/587 (13%)

Query: 42  AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANVLSGA 100
           A  N   +VLD     +K G ++   A +W  N  G+     + +L     Q +NVL   
Sbjct: 99  ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155

Query: 101 CGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159
            G+Q+GDRVA+ +P +PE  + +L C R G +         S  +  R+  S    ++  
Sbjct: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214

Query: 160 ---------------GDEVIQEVDT------------------------------VASEC 174
                           DE +Q+                                 +   C
Sbjct: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274

Query: 175 PSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHS 234
           P ++I      +  D W  + +L+ EA          +++   I +TSG++G PK   H+
Sbjct: 275 PDVQISW---NQGIDLW--WHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHT 329

Query: 235 YSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHL-LPKF- 291
                L       +     A D+ W  +D GWI         P A GA + +   +P + 
Sbjct: 330 VGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYP 389

Query: 292 DPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCVTVGESLLPETLEN 348
           D   +   +  Y +     AP   R+L++   + ++ +    LQ   TVGE + PE    
Sbjct: 390 DVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLW 449

Query: 349 WRAQTGLD---IRESYGQTETG---LTCMVSKTMKIKPG-----YMGTAASCYDVQIIDD 397
           +    G     I +++ QTETG   LT +   T  +KPG     + G A +     I+++
Sbjct: 450 YHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAPA-----ILNE 503

Query: 398 KGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQ 457
            G  L    EG +  +      +    G  +  + T       +++ GD   +D+DGY+ 
Sbjct: 504 SGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYW 563

Query: 458 FMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLS 517
             GR DD++N SG+ +  +EVE+AL+EH AV E AV+  P PV+GE +  FV L     +
Sbjct: 564 ITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGH-T 622

Query: 518 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
             P +LT+EL++ ++    P   P  I+    LPKT +GKI R  LR
Sbjct: 623 FSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 668


>gi|253970489 acyl-CoA synthetase short-chain family member 2
           isoform 2 [Homo sapiens]
          Length = 714

 Score =  152 bits (383), Expect = 1e-36
 Identities = 152/595 (25%), Positives = 249/595 (41%), Gaps = 84/595 (14%)

Query: 42  AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANVLSGA 100
           A  N   +VLD     +K G ++   A +W  N  G+     + +L     Q +NVL   
Sbjct: 99  ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155

Query: 101 CGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159
            G+Q+GDRVA+ +P +PE  + +L C R G +         S  +  R+  S    ++  
Sbjct: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214

Query: 160 ---------------GDEVIQEVDT------------------------------VASEC 174
                           DE +Q+                                 +   C
Sbjct: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274

Query: 175 PSLRIKLLVSEKSCDGWLNFKK--------LLNEASTTHHCVETGSQEASAIYFTSGTSG 226
           P ++ KL    K     +++ +        L+ EA          +++   I +TSG++G
Sbjct: 275 PDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTG 334

Query: 227 LPKMAEHSYSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILNILCSLMEPWALGACTFV 285
            PK   H+     L       +     A D+ W  +D GWI         P A GA + +
Sbjct: 335 KPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVL 394

Query: 286 HL-LPKF-DPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCVTVGES 340
              +P + D   +   +  Y +     AP   R+L++   + ++ +    LQ   TVGE 
Sbjct: 395 FEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEP 454

Query: 341 LLPETLENWRAQTGLD---IRESYGQTETG---LTCMVSKTMKIKPG-----YMGTAASC 389
           + PE    +    G     I +++ QTETG   LT +   T  +KPG     + G A + 
Sbjct: 455 INPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAPA- 512

Query: 390 YDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGI 449
               I+++ G  L    EG +  +      +    G  +  + T       +++ GD   
Sbjct: 513 ----ILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQ 568

Query: 450 KDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFV 509
           +D+DGY+   GR DD++N SG+ +  +EVE+AL+EH AV E AV+  P PV+GE +  FV
Sbjct: 569 RDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFV 628

Query: 510 VLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
            L     +  P +LT+EL++ ++    P   P  I+    LPKT +GKI R  LR
Sbjct: 629 TLCDGH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score =  123 bits (309), Expect = 4e-28
 Identities = 129/525 (24%), Positives = 225/525 (42%), Gaps = 67/525 (12%)

Query: 83  FRELSENSQQAANVLSGACGLQRGD----RVAVVLPRVPEWWLVILGCIRAGLIFMPGTI 138
           +REL   S + +  +   CG   GD    RV+ +      + +       +G + +P   
Sbjct: 68  YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127

Query: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198
           +  +  + Y +  S++  ++A  E ++ +  V  +   L + LL    +      +   +
Sbjct: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179

Query: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253
            E +      +    + + I +TSGT+G PK    ++ ++     GL  K    WT    
Sbjct: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234

Query: 254 SDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMMG 310
            D++  +     +  ++ +L+ P  +GA     ++P+F P  +  K LSS    I   M 
Sbjct: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV--MMPEFSPQQVWEKFLSSETPRINVFMA 292

Query: 311 APIVYRMLLQQDLSSYKFPHLQNCVTV-----------GESLLP-ETLENWRAQTGLDIR 358
            P +Y  L++     +  PH Q+ +             G + LP   LE W+  TG  + 
Sbjct: 293 VPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLL 352

Query: 359 ESYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQII-----------------DDKGN 400
           E YG TE G+      T  ++ PG +GT      V+I+                 D++G 
Sbjct: 353 ERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412

Query: 401 VLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMG 460
            + PG E   G  +  +R   +F  Y + P++T +    D W      +  +DG +   G
Sbjct: 413 KVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRG 470

Query: 461 RAD-DIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVL-ASQFLSH 518
           R   DII + GY++   EVE  L+ HP++ + AVI  PD   G+ V A V L     LSH
Sbjct: 471 RTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSH 530

Query: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKL 563
                 +EL++  ++V APY  P ++  V  +P+   GKI +  L
Sbjct: 531 ------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score =  123 bits (309), Expect = 4e-28
 Identities = 129/525 (24%), Positives = 225/525 (42%), Gaps = 67/525 (12%)

Query: 83  FRELSENSQQAANVLSGACGLQRGD----RVAVVLPRVPEWWLVILGCIRAGLIFMPGTI 138
           +REL   S + +  +   CG   GD    RV+ +      + +       +G + +P   
Sbjct: 68  YRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYR 127

Query: 139 QMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLL 198
           +  +  + Y +  S++  ++A  E ++ +  V  +   L + LL    +      +   +
Sbjct: 128 KHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRK---LGVPLLPLTPAI-----YTGAV 179

Query: 199 NEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSL-----GLKAKMDAGWTGLQA 253
            E +      +    + + I +TSGT+G PK    ++ ++     GL  K    WT    
Sbjct: 180 EEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW--AWT---K 234

Query: 254 SDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVIL-KTLSSYP--IKSMMG 310
            D++  +     +  ++ +L+ P  +GA     ++P+F P  +  K LSS    I   M 
Sbjct: 235 DDVILHVLPLHHVHGVVNALLCPLWVGATCV--MMPEFSPQQVWEKFLSSETPRINVFMA 292

Query: 311 APIVYRMLLQQDLSSYKFPHLQNCVTV-----------GESLLP-ETLENWRAQTGLDIR 358
            P +Y  L++     +  PH Q+ +             G + LP   LE W+  TG  + 
Sbjct: 293 VPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLL 352

Query: 359 ESYGQTETGLTCMVSKTMKIK-PGYMGTAASCYDVQII-----------------DDKGN 400
           E YG TE G+      T  ++ PG +GT      V+I+                 D++G 
Sbjct: 353 ERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGT 412

Query: 401 VLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMG 460
            + PG E   G  +  +R   +F  Y + P++T +    D W      +  +DG +   G
Sbjct: 413 KVTPGFEEKEGELL--VRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRG 470

Query: 461 RAD-DIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVL-ASQFLSH 518
           R   DII + GY++   EVE  L+ HP++ + AVI  PD   G+ V A V L     LSH
Sbjct: 471 RTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSH 530

Query: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKL 563
                 +EL++  ++V APY  P ++  V  +P+   GKI +  L
Sbjct: 531 ------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score =  113 bits (282), Expect = 5e-25
 Identities = 142/529 (26%), Positives = 229/529 (43%), Gaps = 55/529 (10%)

Query: 77  KELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPG 136
           +++   F +L E   +AA+ L  + GL +GDR+ +  P    W L+ L   +AG+I +  
Sbjct: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154

Query: 137 TIQMKSTDILYRLQMSKAKAIVAGDE--VIQEVDTVASECP-----------SLRIKLLV 183
               ++ ++ Y L+    KA+V   +    Q  + +   CP           S R+  L 
Sbjct: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214

Query: 184 SEKSCDGWLNFKKLLNEA----STTHHC--VETGSQEASA-----IYFTSGTSGLPKMAE 232
           +  S D  L    LL+E     ST  H   ++   Q  S      I FTSGT+G PK A 
Sbjct: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274

Query: 233 HSYSS-------LGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFV 285
            S+ +       LG + K+    T  Q   I+   +     L  +   M     GA T +
Sbjct: 275 LSHYNIVNNSNILGERLKLHEK-TPEQLRMIL--PNPLYHCLGSVAGTMMCLMYGA-TLI 330

Query: 286 HLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ-DLSSYKFPHLQNCVTVGESLLPE 344
              P F+    L+ +S      + G P ++  +L Q D SSY    +   V  G    PE
Sbjct: 331 LASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPE 390

Query: 345 TLENWRAQTGL-DIRESYGQTETGLTCMV---SKTMKIKPGYMGTAASCYDVQIID-DKG 399
            +     +  + D+  +YG TE            T++ K   +G      + +I++ + G
Sbjct: 391 LIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAG 450

Query: 400 NVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQF 458
            +    T G++ IR        +  GY   P KT   +  D W   GD    +E G+ + 
Sbjct: 451 TLAKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKI 505

Query: 459 MGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSH 518
           +GR+ D+I   G  I P+E+E+    HP V E  V+   D   GE + A + L       
Sbjct: 506 VGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL------K 559

Query: 519 DPEQLT-KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDK 566
           D E+ T +E++   K   + +K P+ I FV N P T++GKIQ+ KLR++
Sbjct: 560 DGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608


>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
          Length = 646

 Score = 99.4 bits (246), Expect = 8e-21
 Identities = 137/519 (26%), Positives = 206/519 (39%), Gaps = 52/519 (10%)

Query: 81  WNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQM 140
           W F +L   S   AN+     G   GD VA+ L   PE+  + LG  +AG+      + +
Sbjct: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162

Query: 141 KSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLN----FKK 196
           +   + + L  S AKA++ G E++  V  V+       IK    +   +G L        
Sbjct: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222

Query: 197 LLNEASTT--HHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQAS 254
           LL EAST         G  +     +TSGT+GLPK A   +S     A        +QA+
Sbjct: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAA 282

Query: 255 DIMWTISDTGWILNILCSLMEPWALGACTF----VHLLPKFDPLVILKTLSSYPIKSMMG 310
           D+++        L +  S      +G C      V L  KF           Y    +  
Sbjct: 283 DVLYD------CLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336

Query: 311 APIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGL-DIRESYGQTETGLT 369
              + R LL+Q +   +  H    + VG  L P   E +  + G+  I E YG TE    
Sbjct: 337 IGEICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATE--CN 393

Query: 370 CMVSKTMKIKPGYMGTAASCY--------------DVQIIDDKGNVLPPGTEGDIGIRVK 415
           C ++  M  K G  G  +                  ++++ D   +  P   G+ G+ V 
Sbjct: 394 CSIA-NMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVG 452

Query: 416 PIR---PIGIFSGYVD---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQFMGRADDII 466
            I    P+  F GYV       K A ++  +GD  +L GD  + DE GY  F  R+ D  
Sbjct: 453 QINQQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTF 512

Query: 467 NSSGYRIGPSEVENALMEHPAVVETAVISSPDP-VRGEVVKAFVVLASQFLSHDPEQLTK 525
              G  +  +EVE  L       + AV     P V G+   A V      L  DP  + +
Sbjct: 513 RWRGENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVADPHSLL--DPNAIYQ 570

Query: 526 ELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
           ELQ+    V APY  P  +  +  +  T T KIQ+ +L+
Sbjct: 571 ELQK----VLAPYARPIFLRLLPQVDTTGTFKIQKTRLQ 605


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 124/507 (24%), Positives = 200/507 (39%), Gaps = 49/507 (9%)

Query: 93  AANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGL--IFMPGTIQMKSTDILYRLQ 150
           AA     A  L  G  VA++LP  PE+  +  G  +AGL   F+P  +  +   +L+ L+
Sbjct: 201 AARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTAL--RRGPLLHCLR 258

Query: 151 MSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGW--LNFKKLLNEASTTHHCV 208
              A+A+V   E ++ ++    + P+LR   L    +  G        LL E S      
Sbjct: 259 SCGARALVLAPEFLESLEP---DLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGP 315

Query: 209 ETG------SQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTIS 261
             G      S   + +Y FTSGT+GLPK A  S+  + L+ +      G+   D+++   
Sbjct: 316 VPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKI-LQCQGFYQLCGVHQEDVIYLAL 374

Query: 262 DTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ 321
               +   L  ++    +GA   V L  KF      +    + +        + R L+ Q
Sbjct: 375 PLYHMSGSLLGIVGCMGIGAT--VVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQ 432

Query: 322 DLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTE--------TGLTCMV 372
             S  +  H    + VG  L P+T E +  + G L + E+YG TE        TG    V
Sbjct: 433 PPSKAERGHKVR-LAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAV 491

Query: 373 SKTMKIKPGYMGTAASCYDV----QIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVD 428
            +   +       +   YDV     I D +G+ +   + G+ G+ V P+     F GY  
Sbjct: 492 GRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMAT-SPGEPGLLVAPVSQQSPFLGYAG 550

Query: 429 NPDKTAANIRGD-------FWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENA 481
            P+     +  D       F+  GD  + D+ G+ +F  R  D     G  +  +EV   
Sbjct: 551 GPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEV 610

Query: 482 LMEHPAVVETAVISSPDP-VRGEVVKAFVVLASQFLSHDPEQL-TKELQQHVKSVTAPYK 539
                 + E  V     P   G    A +VL        P  L   +L  HV     PY 
Sbjct: 611 FEALDFLQEVNVYGVTVPGHEGRAGMAALVL------RPPHALDLMQLYTHVSENLPPYA 664

Query: 540 YPRKIEFVLNLPKTVTGKIQRAKLRDK 566
            PR +    +L  T T K Q+ ++ ++
Sbjct: 665 RPRFLRLQESLATTETFKQQKVRMANE 691


>gi|40807357 solute carrier family 27 (fatty acid transporter),
           member 4 [Homo sapiens]
          Length = 643

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 129/527 (24%), Positives = 207/527 (39%), Gaps = 57/527 (10%)

Query: 75  KGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFM 134
           +G +  W FR+L E S   AN L  A GL  GD  A+ +    E+  + LG  + G+   
Sbjct: 96  EGTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAA 154

Query: 135 PGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTV-ASECPSLRIKLLVSEKSCDG-WL 192
                ++   +L+ L  S+A+A+V G E+   +  V AS  PSL +        C G W 
Sbjct: 155 LINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSL-------FCSGSWE 207

Query: 193 ---------NFKKLLNEAST-THHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKA 242
                    +   LL +A      C + G  +     +TSGT+GLPK A   +S     A
Sbjct: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267

Query: 243 KMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTF----VHLLPKFDPLVILK 298
            +      ++ +DI++        L +  S      +G C      V +  KF       
Sbjct: 268 ALVYYGFRMRPNDIVYD------CLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWD 321

Query: 299 TLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTGL-DI 357
               Y    +     + R LL Q     +  H Q  + +G  L      N+ ++  +  +
Sbjct: 322 DCIKYNCTIVQYIGELCRYLLNQPPREAENQH-QVRMALGNGLRQSIWTNFSSRFHIPQV 380

Query: 358 RESYGQTETGLTCMVSKTMKIKPGYMGTAAS-CYDVQII-----------DDKGNVLP-- 403
            E YG TE   +     +     G+     S  Y ++++              G  +P  
Sbjct: 381 AEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQ 440

Query: 404 PGTEGDIGIRVKPIRPIGIFSGYVD---NPDKTAANI--RGD-FWLLGDRGIKDEDGYFQ 457
           PG  G +  R+    P+  F GY++   N  K A ++  +GD  +L GD  + DE GY  
Sbjct: 441 PGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLY 500

Query: 458 FMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLS 517
           F  R  D     G  +  +EVE  L     + + AV     P   E       +AS   +
Sbjct: 501 FRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVP-GTEGRAGMAAVASPTGN 559

Query: 518 HDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
            D E+  + L++ +      Y  P  +  +  L KT T K Q+ +LR
Sbjct: 560 CDLERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELR 602


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 108/513 (21%), Positives = 200/513 (38%), Gaps = 47/513 (9%)

Query: 83  FRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
           + ++   S Q A  L    GL++GD VA+++   P +  + LG ++ G         +++
Sbjct: 81  YAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRA 140

Query: 143 TDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR-----IKLLVSEKSCDGWLNFKKL 197
             +L+  Q   AK ++   E+   V+ +    PSL+     I  +    + DG  +F   
Sbjct: 141 KSLLHCFQCCGAKVLLVSPELQAAVEEI---LPSLKKDDVSIYYVSRTSNTDGIDSFLDK 197

Query: 198 LNEASTTHHCVETGSQEAS----AIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQ 252
           ++E S T    E+   E +    A+Y +TSGT+GLPK A  ++  +     +    +GL+
Sbjct: 198 VDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGL-TFVSGLK 255

Query: 253 ASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAP 312
           A D+++          +L  +      GA   + L  KF           Y +  +    
Sbjct: 256 ADDVIYITLPFYHSAALLIGIHGCIVAGAT--LALRTKFSASQFWDDCRKYNVTVIQYIG 313

Query: 313 IVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTETGLTCM 371
            + R L           H    + +G  L  +    +  + G + I E Y  TE  +  M
Sbjct: 314 ELLRYLCNSPQKPNDRDHKVR-LALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFM 372

Query: 372 VSKTMKI----KPGYMGTAASCYDV--------QIIDDKGNVLPPGTEGDIGIRVKPIRP 419
            +   K+    +  Y+      YD+        + + D+        +G++G+ V  I  
Sbjct: 373 -NYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQ 431

Query: 420 IGIFSGYVDNPDKTAAN------IRGDFWL-LGDRGIKDEDGYFQFMGRADDIINSSGYR 472
           +  F+GY     +T          +GD +   GD  + D + +  F  R  D     G  
Sbjct: 432 LTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGEN 491

Query: 473 IGPSEVEN--ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQH 530
           +  +EV +   L++    V    +  PD       +  + +AS  +  + E   K+L QH
Sbjct: 492 VATTEVADTVGLVDFVQEVNVYGVHVPDH------EGRIGMASIKMKENHEFDGKKLFQH 545

Query: 531 VKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKL 563
           +      Y  PR +     +  T T K ++  L
Sbjct: 546 IADYLPSYARPRFLRIQDTIEITGTFKHRKMTL 578


>gi|62865631 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 90/431 (20%), Positives = 173/431 (40%), Gaps = 37/431 (8%)

Query: 80  MWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQ 139
           ++ ++++ + S + A+V      L++GD VA+++   P++  V  G  + G +       
Sbjct: 79  IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138

Query: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196
           ++S  +L  ++    +A+V G +++  V+ +    PSL   + V    +    G ++ K+
Sbjct: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195

Query: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250
            L+ +       +HH V     +++ +Y FTSGT+GLPK A  S   + L+        G
Sbjct: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252

Query: 251 LQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMG 310
             A DI++           +  +     LGA     L  KF           Y +     
Sbjct: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCV--LKKKFSASQFWSDCKKYDVTVFQY 310

Query: 311 APIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTETGLT 369
              + R L +Q     +  H    + +G  +  +    +  + G + + E Y  TE+ ++
Sbjct: 311 IGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATESSIS 369

Query: 370 CM--------VSKTMKIKPGYMGTAASCYDVQIIDDKGNV------LPPGTEGDIGIRVK 415
            M        + +T              YD Q  +   N       +  G  G +  RV 
Sbjct: 370 FMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVN 429

Query: 416 PIRPIGIFSG-YVDNPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIINSSGY 471
              P   ++G Y    DK   ++  +GD +L  GD  ++D+D +  F  R  D     G 
Sbjct: 430 AKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGE 489

Query: 472 RIGPSEVENAL 482
            +  +EV + +
Sbjct: 490 NVATTEVADVI 500


>gi|13325055 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 90/431 (20%), Positives = 173/431 (40%), Gaps = 37/431 (8%)

Query: 80  MWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQ 139
           ++ ++++ + S + A+V      L++GD VA+++   P++  V  G  + G +       
Sbjct: 79  IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138

Query: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196
           ++S  +L  ++    +A+V G +++  V+ +    PSL   + V    +    G ++ K+
Sbjct: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195

Query: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250
            L+ +       +HH V     +++ +Y FTSGT+GLPK A  S   + L+        G
Sbjct: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252

Query: 251 LQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMG 310
             A DI++           +  +     LGA     L  KF           Y +     
Sbjct: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCV--LKKKFSASQFWSDCKKYDVTVFQY 310

Query: 311 APIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTETGLT 369
              + R L +Q     +  H    + +G  +  +    +  + G + + E Y  TE+ ++
Sbjct: 311 IGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATESSIS 369

Query: 370 CM--------VSKTMKIKPGYMGTAASCYDVQIIDDKGNV------LPPGTEGDIGIRVK 415
            M        + +T              YD Q  +   N       +  G  G +  RV 
Sbjct: 370 FMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVN 429

Query: 416 PIRPIGIFSG-YVDNPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIINSSGY 471
              P   ++G Y    DK   ++  +GD +L  GD  ++D+D +  F  R  D     G 
Sbjct: 430 AKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGE 489

Query: 472 RIGPSEVENAL 482
            +  +EV + +
Sbjct: 490 NVATTEVADVI 500


>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
           b [Homo sapiens]
          Length = 722

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 15/179 (8%)

Query: 335 VTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQI 394
           VT      P  L   RA  G  + E YGQTE    C  +       G++G    C  +++
Sbjct: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516

Query: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDE 452
           +D ++ N      EG+I +R        +F GY+ +PD+T   +  D WL  GD G    
Sbjct: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571

Query: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510
            G  + + R   I   + G  + P ++EN  +    V +         V G+ +KAF+V
Sbjct: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 82  NFRELSENSQ-QAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMP----- 135
           +++E+++ ++   + +L   C       + V     PEW +V L C    ++ +P     
Sbjct: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206

Query: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185
             G I+  + + DI   +     KA++  + V ++      E P L++ +L+        
Sbjct: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260

Query: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231
              + C   +   + + +    +H      Q  + S + FTSGT+G PK A
Sbjct: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311


>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
           a [Homo sapiens]
          Length = 722

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 15/179 (8%)

Query: 335 VTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQI 394
           VT      P  L   RA  G  + E YGQTE    C  +       G++G    C  +++
Sbjct: 457 VTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKL 516

Query: 395 ID-DKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDE 452
           +D ++ N      EG+I +R        +F GY+ +PD+T   +  D WL  GD G    
Sbjct: 517 VDVEELNYWACKGEGEICVRGP-----NVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP 571

Query: 453 DGYFQFMGRADDIIN-SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510
            G  + + R   I   + G  + P ++EN  +    V +         V G+ +KAF+V
Sbjct: 572 AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIY-------VHGDSLKAFLV 623



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 82  NFRELSENSQ-QAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMP----- 135
           +++E+++ ++   + +L   C       + V     PEW +V L C    ++ +P     
Sbjct: 147 SYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTL 206

Query: 136 --GTIQ--MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSE------ 185
             G I+  + + DI   +     KA++  + V ++      E P L++ +L+        
Sbjct: 207 GPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK------ETPGLKLIILMDPFEEALK 260

Query: 186 ---KSCDGWLNFKKLLNEASTTHHCVETGSQ--EASAIYFTSGTSGLPKMA 231
              + C   +   + + +    +H      Q  + S + FTSGT+G PK A
Sbjct: 261 ERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGA 311


>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
           sapiens]
          Length = 698

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 15/164 (9%)

Query: 350 RAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIID-DKGNVLPPGTEG 408
           RA  G    E YGQTE    C ++       G++G    C  ++++D ++ N +    EG
Sbjct: 447 RAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKLVDVEEMNYMAAEGEG 506

Query: 409 DIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467
           ++ ++        +F GY+ +P KTA  +  D WL  GD G    +G  + + R   I  
Sbjct: 507 EVCVKGP-----NVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFK 561

Query: 468 -SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510
            + G  I P ++EN  M    V +         V GE ++AF++
Sbjct: 562 LAQGEYIAPEKIENIYMRSEPVAQVF-------VHGESLQAFLI 598


>gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]
          Length = 1133

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 28/41 (68%), Positives = 32/41 (78%)

Query: 504 VVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 544
           +VK  +VL  QFLSHD  QLTKELQQHVKSVT P +Y RK+
Sbjct: 1   MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41


>gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-chain
           family member 2 [Homo sapiens]
          Length = 1122

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 28/41 (68%), Positives = 32/41 (78%)

Query: 504 VVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 544
           +VK  +VL  QFLSHD  QLTKELQQHVKSVT P +Y RK+
Sbjct: 1   MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41


>gi|239745482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 449

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 27/42 (64%), Positives = 32/42 (76%)

Query: 503 EVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKI 544
           ++VK  +VL  QFLSHD  Q TKELQQHVKSVT P +Y RK+
Sbjct: 17  QMVKLSIVLTPQFLSHDQSQFTKELQQHVKSVTCPCEYLRKV 58


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,707,561
Number of Sequences: 37866
Number of extensions: 956905
Number of successful extensions: 2358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2237
Number of HSP's gapped (non-prelim): 85
length of query: 577
length of database: 18,247,518
effective HSP length: 108
effective length of query: 469
effective length of database: 14,157,990
effective search space: 6640097310
effective search space used: 6640097310
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.