Guide to the Human Genome
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Search of human proteins with 5803197

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5803197 testisin isoform 1 [Homo sapiens]
         (314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5803197 testisin isoform 1 [Homo sapiens]                          670   0.0  
gi|21614531 testisin isoform 2 [Homo sapiens]                         660   0.0  
gi|21614533 testisin isoform 3 [Homo sapiens]                         629   0.0  
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         336   2e-92
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      223   2e-58
gi|13994276 marapsin [Homo sapiens]                                   218   4e-57
gi|4506153 prostasin preproprotein [Homo sapiens]                     213   2e-55
gi|148806900 epidermis-specific serine protease-like protein [Ho...   202   2e-52
gi|11545839 protease, serine, 22 [Homo sapiens]                       202   3e-52
gi|58218970 protease, serine, 36 [Homo sapiens]                       202   4e-52
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         196   2e-50
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           195   5e-50
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  193   1e-49
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             193   2e-49
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   192   4e-49
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            191   6e-49
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]          190   1e-48
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ...   190   1e-48
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ...   190   1e-48
gi|117956391 protease, serine, 33 [Homo sapiens]                      188   6e-48
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          186   2e-47
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           184   1e-46
gi|4503627 coagulation factor XI precursor [Homo sapiens]             183   2e-46
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...   182   4e-46
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...   182   4e-46
gi|33186882 testis serine protease 2 [Homo sapiens]                   179   3e-45
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]         179   4e-45
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          179   4e-45
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]       179   4e-45
gi|33695155 hepsin [Homo sapiens]                                     177   8e-45

>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  670 bits (1728), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR 60
           MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR
Sbjct: 1   MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR 60

Query: 61  LWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF 120
           LWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF
Sbjct: 61  LWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF 120

Query: 121 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK 180
           VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK
Sbjct: 121 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK 180

Query: 181 EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGG 240
           EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGG
Sbjct: 181 EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGG 240

Query: 241 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL 300
           PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL
Sbjct: 241 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL 300

Query: 301 FFPLLWALPLLGPV 314
           FFPLLWALPLLGPV
Sbjct: 301 FFPLLWALPLLGPV 314


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  660 bits (1704), Expect = 0.0
 Identities = 312/314 (99%), Positives = 312/314 (99%), Gaps = 2/314 (0%)

Query: 1   MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR 60
           MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR
Sbjct: 1   MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR 60

Query: 61  LWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF 120
           LWDSHVCGVSLLSHRWALTAAHCFET  DLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF
Sbjct: 61  LWDSHVCGVSLLSHRWALTAAHCFET--DLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF 118

Query: 121 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK 180
           VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK
Sbjct: 119 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK 178

Query: 181 EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGG 240
           EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGG
Sbjct: 179 EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGG 238

Query: 241 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL 300
           PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL
Sbjct: 239 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL 298

Query: 301 FFPLLWALPLLGPV 314
           FFPLLWALPLLGPV
Sbjct: 299 FFPLLWALPLLGPV 312


>gi|21614533 testisin isoform 3 [Homo sapiens]
          Length = 300

 Score =  629 bits (1623), Expect = 0.0
 Identities = 300/314 (95%), Positives = 300/314 (95%), Gaps = 14/314 (4%)

Query: 1   MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR 60
           MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR
Sbjct: 1   MGARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR 60

Query: 61  LWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF 120
           LWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF
Sbjct: 61  LWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF 120

Query: 121 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK 180
           VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK
Sbjct: 121 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIK 180

Query: 181 EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGG 240
           EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDM              GDSGG
Sbjct: 181 EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDM--------------GDSGG 226

Query: 241 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL 300
           PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL
Sbjct: 227 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWPLL 286

Query: 301 FFPLLWALPLLGPV 314
           FFPLLWALPLLGPV
Sbjct: 287 FFPLLWALPLLGPV 300


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  336 bits (861), Expect = 2e-92
 Identities = 172/322 (53%), Positives = 218/322 (67%), Gaps = 20/322 (6%)

Query: 1   MGARGALLLALLLARAGLRKPESQEAAPLSGP--------------CGRRVITSRIVGGE 46
           MGARGALLLALLLARAGL KP  +  A  +GP              CG R I + + GG 
Sbjct: 1   MGARGALLLALLLARAGLGKP-GELGALQAGPGAARRPGGGGREEACGHREIHALVAGGV 59

Query: 47  DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSM 106
           ++  GRWPWQ SLRL   H CG SLLS RW L+AAHCF+ +     PS W VQ G+LTS 
Sbjct: 60  ESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYY---PSEWTVQLGELTSR 116

Query: 107 PSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFE 166
           P+ W+L+AY +RY V +I ++P  LG    DIAL++L++ VTY  +IQPIC+++STF F 
Sbjct: 117 PTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTFNFV 176

Query: 167 NRTDCWVTGWGYIKEDEA-LPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAG 225
           +R DCWVTGWG I      LP P+ L+E QV I+NN+ CN+LF + S R  I+  M CAG
Sbjct: 177 HRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAG 236

Query: 226 NAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 285
              G  D C GDSGGPL C+K+GLWYQ+G+VSWG+ CG+PNRPGVYTNIS +F WI+++M
Sbjct: 237 AEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVM 296

Query: 286 AQSGMSQPDPSWPLLFFPLLWA 307
           + S   +P+PS  LL   LLWA
Sbjct: 297 SHS-TPRPNPSQLLLLLALLWA 317


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  223 bits (568), Expect = 2e-58
 Identities = 139/323 (43%), Positives = 178/323 (55%), Gaps = 45/323 (13%)

Query: 3   ARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITS---RIVGGEDAELGRWPWQGSL 59
           A GA  L LLLA  G+          L   CGR  ++    RIVGG  A  G WPWQ SL
Sbjct: 2   ALGACGLLLLLAVPGV------SLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASL 55

Query: 60  RLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQL--TSMPSFWSLQAYYT 117
           RL   HVCG SLLS +W LTAAHCF    + SD   + V  G+L  T  P F +++    
Sbjct: 56  RLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSD---YQVHLGELEITLSPHFSTVRQII- 111

Query: 118 RYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWG 177
                 ++ SP     +  DIALV+LS PVT +  I P+CL  ++ +F     CWVTGWG
Sbjct: 112 ------LHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWG 165

Query: 178 YIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFG--------DMVCAGNAQG 229
           Y +E E LP P++L+EV+V++++   C         R+D  G        DM+CA   +G
Sbjct: 166 YTREGEPLPPPYSLREVKVSVVDTETC---------RRDYPGPGGSILQPDMLCA---RG 213

Query: 230 GKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSG 289
             DAC  DSGGPL C  NG W Q G+VSWG GCGRPNRPGVYT +  +  WI++ +  SG
Sbjct: 214 PGDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASG 273

Query: 290 MSQPD-PSWPLL---FFPLLWAL 308
            S+   P  PLL   F P L+ L
Sbjct: 274 GSESGYPRLPLLAGFFLPGLFLL 296


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  218 bits (556), Expect = 4e-57
 Identities = 121/287 (42%), Positives = 166/287 (57%), Gaps = 18/287 (6%)

Query: 4   RGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWD 63
           R A +  LLL   G ++ ++  A      CGR  + +R+VGG+D + G WPWQ S++   
Sbjct: 3   RPAAVPLLLLLCFGSQRAKAATA------CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNG 56

Query: 64  SHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSN 123
           SH CG SL++ +W LTAAHCF    + S+ S + V  G    +       A Y R  V  
Sbjct: 57  SHFCGGSLIAEQWVLTAAHCFR---NTSETSLYQVLLGARQLVQP--GPHAMYAR--VRQ 109

Query: 124 IYLSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182
           +  +P Y G  S  D+ALV+L APV +T +I P+CL   +  FE   +CWVTGWG   E+
Sbjct: 110 VESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEE 169

Query: 183 EALPSPHTLQEVQVAIINNSMCNHLFLK---YSFR-KDIFGDMVCAGNAQGGKDACFGDS 238
           + LP P  LQ++ V II+   CN L+ K   + ++ K I  DM+CAG  +G KDAC GDS
Sbjct: 170 DLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDS 229

Query: 239 GGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 285
           GGPL C     W Q GV+SWG GC R NRPGVY  ++ H  WI +++
Sbjct: 230 GGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  213 bits (542), Expect = 2e-55
 Identities = 134/336 (39%), Positives = 178/336 (52%), Gaps = 43/336 (12%)

Query: 9   LALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCG 68
           +A+LL    LR     E A    PCG     +RI GG  A  G+WPWQ S+     HVCG
Sbjct: 15  VAILLYLGLLRSGTGAEGA--EAPCGVAP-QARITGGSSAVAGQWPWQVSITYEGVHVCG 71

Query: 69  VSLLSHRWALTAAHCFETYSDLSDPSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIYL 126
            SL+S +W L+AAHCF +         + V+ G  QL S      +        + +I  
Sbjct: 72  GSLVSEQWVLSAAHCFPSEHH---KEAYEVKLGAHQLDSYSEDAKVST------LKDIIP 122

Query: 127 SPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEAL 185
            P YL   S  DIAL++LS P+T++++I+PICL A+   F N   C VTGWG++    +L
Sbjct: 123 HPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSL 182

Query: 186 PSPHTLQEVQVAIINNSMCNHLF---LKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPL 242
            +P  LQ+++V +I+   CN L+    K      +  DMVCAG  +GGKDAC GDSGGPL
Sbjct: 183 LTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPL 242

Query: 243 ACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ--------KLMAQSGMSQPD 294
           +C   GLWY  G+VSWG  CG  NRPGVYT  S +  WIQ        +++ Q+  SQPD
Sbjct: 243 SCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPD 302

Query: 295 PSW-----------------PLLFFPLLWALPLLGP 313
            +                  P+LF PL  AL LL P
Sbjct: 303 SNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSP 338


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  202 bits (515), Expect = 2e-52
 Identities = 114/284 (40%), Positives = 164/284 (57%), Gaps = 18/284 (6%)

Query: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFE-TYSDLS 91
           CG+ V +SR+VGG+DA  GRWPWQ SL    + +CG SL+S R  LTAAHC + T++  S
Sbjct: 19  CGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFS 78

Query: 92  DPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTK 151
               + V  G +T   S         +Y+VS I + P+Y   +  D+AL+KLS+ VT+T 
Sbjct: 79  ----YTVWLGSITVGDS-----RKRVKYYVSKIVIHPKYQDTTA-DVALLKLSSQVTFTS 128

Query: 152 HIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211
            I PICL + T +      CWVTGWG +KE         LQE +V II+   C  L+   
Sbjct: 129 AILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPI 188

Query: 212 -----SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPN 266
                +    I  D +CAG+ Q  KD+C GDSGGPL+C+ +G+W Q GVVSWG+ CG+ +
Sbjct: 189 GIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGK-S 247

Query: 267 RPGVYTNISHHFEWIQKLMAQ-SGMSQPDPSWPLLFFPLLWALP 309
            PGVYTN+ ++ +WI   +++ + +   D  +P++   L    P
Sbjct: 248 LPGVYTNVIYYQKWINATISRANNLDFSDFLFPIVLLSLALLRP 291


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  202 bits (514), Expect = 3e-52
 Identities = 106/289 (36%), Positives = 162/289 (56%), Gaps = 17/289 (5%)

Query: 2   GARGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL 61
           G  G     LLLA   +    +    P+   CG+    +R+VGGED+    WPW  S++ 
Sbjct: 13  GCLGTFTSLLLLASTAIL---NAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQK 69

Query: 62  WDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTR-YF 120
             +H C  SLL+ RW +TAAHCF+   +L+ P  + V  G        W L    +R   
Sbjct: 70  NGTHHCAGSLLTSRWVITAAHCFK--DNLNKPYLFSVLLGA-------WQLGNPGSRSQK 120

Query: 121 VSNIYLSPR----YLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGW 176
           V   ++ P     +   +  DIALV+L   + +++ + PICL  ++      T CW++GW
Sbjct: 121 VGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGW 180

Query: 177 GYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFG 236
           G I++   LP P TLQ+++V II++ +C+HL+ + + +  I  DM+CAG  +G +DAC G
Sbjct: 181 GSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLG 240

Query: 237 DSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 285
           DSGGPL C  +G W   G++SWG GC   NRPGVY ++S H  W++K++
Sbjct: 241 DSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIV 289


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  202 bits (513), Expect = 4e-52
 Identities = 104/281 (37%), Positives = 158/281 (56%), Gaps = 11/281 (3%)

Query: 21  PESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTA 80
           P  +E   L   CGR   ++RIVGG +A+ G WPWQ SL     H+CG SL++  W L+A
Sbjct: 28  PTQEEPEDLD--CGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSA 85

Query: 81  AHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIAL 140
           AHCF T   L   + W V  G  +       L   +TR   + +  +         D+AL
Sbjct: 86  AHCFMTNGTLEPAAEWSVLLGVHSQDGP---LDGAHTRAVAAIVVPANYSQVELGADLAL 142

Query: 141 VKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIIN 200
           ++L++P +    + P+CL  ++  F + T CW TGWG ++E + LP P  LQEV++ ++ 
Sbjct: 143 LRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLG 202

Query: 201 NSMCNHLFLK---YSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVS 257
            + C  L+ +   ++    I   M+CAG  +G +D C GDSGGPL C + G W+Q G+ S
Sbjct: 203 EATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITS 262

Query: 258 WGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQPDPSWP 298
           +G GCGR NRPGV+T ++ +  WI++   Q   S+P P++P
Sbjct: 263 FGFGCGRRNRPGVFTAVATYEAWIRE---QVMGSEPGPAFP 300



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 59/245 (24%), Positives = 95/245 (38%), Gaps = 28/245 (11%)

Query: 45  GEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCF----ETYSDLSDPSGWMVQF 100
           G+    G WPW+  + +  S  C  +L+S  W L  A CF     + S   D   W V  
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRV-- 383

Query: 101 GQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQA 160
             L S P             V+ +        ++  D+AL++L  PV  +   +P+CL  
Sbjct: 384 -LLPSRP---------RAERVARLVQHENASWDNASDLALLQLRTPVNLSAASRPVCLPH 433

Query: 161 STFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGD 220
               F   + C +  WG     E    P  L E +  ++    C+ L+ +      + GD
Sbjct: 434 PEHYFLPGSRCRLARWG---RGEPALGPGALLEAE--LLGGWWCHCLYGRQGAAVPLPGD 488

Query: 221 ----MVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISH 276
               +  A   +    +C+ DS   L C + G W+  G+  +  GC RP     +  +  
Sbjct: 489 PPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLRPR---AFFPLQT 545

Query: 277 HFEWI 281
           H  WI
Sbjct: 546 HGPWI 550



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 74/285 (25%), Positives = 116/285 (40%), Gaps = 45/285 (15%)

Query: 22  ESQEAAPLS--GPCGRRVITSRIVGGEDAELG-RWPWQGSLRLWDSHVCGVSLLSHRWAL 78
           E+Q   P +  G CG R+        E A +G  WPW   + +    VC   LL+  W L
Sbjct: 575 ETQTCPPHTEHGACGLRL--------EAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVL 626

Query: 79  TAAHCFETYSDLSDP--SGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPY 136
            A HC       + P    ++ + G  +S+P     Q +     V +I L P++LG  P 
Sbjct: 627 AATHCVLRPGSTTVPYIEVYLGRAG-ASSLP-----QGHQVSRLVISIRL-PQHLGLRP- 678

Query: 137 DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQV 196
            +AL++LS+ V  +    PICL  +         CWV GW   KE    P         V
Sbjct: 679 PLALLELSSRVEPSPSALPICLHPA--GIPPGASCWVLGW---KE----PQDRVPVAAAV 729

Query: 197 AIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACN-KNGLWYQIGV 255
           +I+   +C+ L     ++  +    +C   A+G ++ C   S  PL C    G W  +G+
Sbjct: 730 SILTQRICDCL-----YQGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGM 784

Query: 256 VSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMSQP--DPSWP 298
              G          ++  I     WI + + ++    P   P WP
Sbjct: 785 AVQG-------SRELFAAIGPEEAWISQTVGEANFLPPSGSPHWP 822


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  196 bits (499), Expect = 2e-50
 Identities = 105/256 (41%), Positives = 142/256 (55%), Gaps = 17/256 (6%)

Query: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
           CG R +T RIVGG  A   +WPWQ SL    +H+CG +L+  +W LTAAHCF    +   
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTRE-KV 375

Query: 93  PSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSP-YDIALVKLSAPVTY 149
             GW V  G   L  +P   S         ++ I ++  Y      YDIAL++LS P+T 
Sbjct: 376 LEGWKVYAGTSNLHQLPEAAS---------IAEIIINSNYTDEEDDYDIALMRLSKPLTL 426

Query: 150 TKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFL 209
           + HI P CL      F     CW+TG+G  +E +   SP  L+EVQV +I+   CN   +
Sbjct: 427 SAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPF-LREVQVNLIDFKKCNDYLV 485

Query: 210 KYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPG 269
             S+   +   M+CAG+ +GG+D+C GDSGGPL C +N  WY  GV SWG GCG+ N+PG
Sbjct: 486 YDSY---LTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPG 542

Query: 270 VYTNISHHFEWIQKLM 285
           VYT ++    WI   M
Sbjct: 543 VYTKVTEVLPWIYSKM 558


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  195 bits (495), Expect = 5e-50
 Identities = 104/255 (40%), Positives = 153/255 (60%), Gaps = 14/255 (5%)

Query: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
           CG +  +SRIVGG  +  G WPWQ SL++   H+CG +L++ RW +TAAHCF+  S ++ 
Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDS-MAS 626

Query: 93  PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNS-PYDIALVKLSAPVTYTK 151
              W V  G++    S W  +  +    VS + L P +  +S  YD+AL++L  PV  + 
Sbjct: 627 TVLWTVFLGKVW-QNSRWPGEVSFK---VSRLLLHPYHEEDSHDYDVALLQLDHPVVRSA 682

Query: 152 HIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211
            ++P+CL A +  FE    CW+TGWG ++E    P  + LQ+V V +I   +C+ +    
Sbjct: 683 AVRPVCLPARSHFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQDLCSEV---- 736

Query: 212 SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNK-NGLWYQIGVVSWGVGCGRPNRPGV 270
            +R  +   M+CAG  +G KDAC GDSGGPL C   +G W+  G+VSWG+GCGRPN  GV
Sbjct: 737 -YRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGV 795

Query: 271 YTNISHHFEWIQKLM 285
           YT I+    WIQ+++
Sbjct: 796 YTRITGVISWIQQVV 810


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  193 bits (491), Expect = 1e-49
 Identities = 108/266 (40%), Positives = 149/266 (56%), Gaps = 26/266 (9%)

Query: 26  AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDS---HVCGVSLLSHRWALTAAH 82
           AAP  G   +RV    IVGG++A   +WPWQ SLR+ D    H CG SL+  +W LTAAH
Sbjct: 18  AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAH 74

Query: 83  CFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDIA 139
           C     D+ D +   VQ  +            YY      VS I + P+ Y      DIA
Sbjct: 75  CVGP--DVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADIA 123

Query: 140 LVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAII 199
           L++L  PV  + H+  + L  ++  F     CWVTGWG +  DE LP P  L++V+V I+
Sbjct: 124 LLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIM 183

Query: 200 NNSMCNHLFLKYSFRKD----IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGV 255
            N +C+  +   ++  D    +  DM+CAGN +  +D+C GDSGGPL C  NG W Q GV
Sbjct: 184 ENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGV 241

Query: 256 VSWGVGCGRPNRPGVYTNISHHFEWI 281
           VSWG GC +PNRPG+YT ++++ +WI
Sbjct: 242 VSWGEGCAQPNRPGIYTRVTYYLDWI 267


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  193 bits (490), Expect = 2e-49
 Identities = 102/259 (39%), Positives = 148/259 (57%), Gaps = 18/259 (6%)

Query: 39  TSRIVGGEDAELGRWPWQGSLRLW---DSHVCGVSLLSHRWALTAAHCFETYSDLSDPSG 95
           ++RIVGG ++  G WPWQ SL++      H+CG SL+ H+W LTAAHCF+    L     
Sbjct: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD---GLPLQDV 444

Query: 96  WMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVTYTKHIQ 154
           W +  G L    S  +    +++  +  I +   Y +    +DIAL+KL AP+ YT+  +
Sbjct: 445 WRIYSGILNL--SDITKDTPFSQ--IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQK 500

Query: 155 PICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFR 214
           PICL +        T+CWVTGWG+ KE   + +   LQ+V + ++ N  C   +  Y   
Sbjct: 501 PICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTNEECQKRYQDYKIT 558

Query: 215 KDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNI 274
           +     MVCAG  +GGKDAC GDSGGPL C  NG+W  +G+ SWG GC R  +PGVYT +
Sbjct: 559 QR----MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKV 614

Query: 275 SHHFEWI-QKLMAQSGMSQ 292
           + + +WI +K  +  G +Q
Sbjct: 615 AEYMDWILEKTQSSDGKAQ 633


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  192 bits (487), Expect = 4e-49
 Identities = 101/259 (38%), Positives = 146/259 (56%), Gaps = 23/259 (8%)

Query: 33  CG-RRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLS 91
           CG RR  +SRIVGG  + L +WPWQ SL+    H+CG S+++  W +TAAHC     DL 
Sbjct: 207 CGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVY---DLY 263

Query: 92  DPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTK 151
            P  W +Q G ++ + +     ++     V +    P+ LGN   DIAL+KL+ P+T+ +
Sbjct: 264 LPKSWTIQVGLVSLLDN--PAPSHLVEKIVYHSKYKPKRLGN---DIALMKLAGPLTFNE 318

Query: 152 HIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211
            IQP+CL  S   F +   CW +GWG  ++     SP  L    V +I+N +CNH     
Sbjct: 319 MIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASP-VLNHAAVPLISNKICNH----- 372

Query: 212 SFRKDIFG-----DMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPN 266
              +D++G      M+CAG   GG D+C GDSGGPL C +  LW  +G  S+G+GC   N
Sbjct: 373 ---RDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVN 429

Query: 267 RPGVYTNISHHFEWIQKLM 285
           +PGVYT ++   +WI + M
Sbjct: 430 KPGVYTRVTSFLDWIHEQM 448


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  191 bits (486), Expect = 6e-49
 Identities = 108/267 (40%), Positives = 149/267 (55%), Gaps = 28/267 (10%)

Query: 26  AAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL----WDSHVCGVSLLSHRWALTAA 81
           AAP  G   +RV    IVGG++A   +WPWQ SLR+    W  H CG SL+  +W LTAA
Sbjct: 18  AAPAPGQALQRV---GIVGGQEAPRSKWPWQVSLRVHGPYW-MHFCGGSLIHPQWVLTAA 73

Query: 82  HCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYF--VSNIYLSPR-YLGNSPYDI 138
           HC     D+ D +   VQ  +            YY      VS I + P+ Y      DI
Sbjct: 74  HCVGP--DVKDLAALRVQLREQ---------HLYYQDQLLPVSRIIVHPQFYTAQIGADI 122

Query: 139 ALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAI 198
           AL++L  PV  + H+  + L  ++  F     CWVTGWG +  DE LP P  L++V+V I
Sbjct: 123 ALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPI 182

Query: 199 INNSMCNHLFLKYSFRKD----IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIG 254
           + N +C+  +   ++  D    +  DM+CAGN +  +D+C GDSGGPL C  NG W Q G
Sbjct: 183 MENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAG 240

Query: 255 VVSWGVGCGRPNRPGVYTNISHHFEWI 281
           VVSWG GC +PNRPG+YT ++++ +WI
Sbjct: 241 VVSWGEGCAQPNRPGIYTRVTYYLDWI 267


>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
          Length = 410

 Score =  190 bits (483), Expect = 1e-48
 Identities = 108/254 (42%), Positives = 138/254 (54%), Gaps = 15/254 (5%)

Query: 30  SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89
           S  CG RV  SR++GG  A   +WPWQ SL+  + H CG SL+  RW LTAAHC      
Sbjct: 153 SQACGHRV--SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC------ 204

Query: 90  LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTY 149
           +    GW      L  +   W  QA+  ++    I+ S         DIAL  L+  V Y
Sbjct: 205 VFRGCGWEGGRWLLAGIGR-WD-QAW--KHLEDIIFPSNFDFATLTSDIALALLAYSVNY 260

Query: 150 TKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFL 209
           + HIQP CL    FE E  T+CWVTGWG + E  + P P  LQE ++ I+ +  C  +  
Sbjct: 261 SSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLK 320

Query: 210 KYSFRKD--IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNR 267
             +  K   +    VC  N QG KDAC GDSGGPL C  NG W Q+G+VSWG+GCGR   
Sbjct: 321 NKNISKSKMVTRGTVCGYNDQG-KDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGY 379

Query: 268 PGVYTNISHHFEWI 281
           PGVYT +S + +WI
Sbjct: 380 PGVYTEVSFYKKWI 393


>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
           sapiens]
          Length = 410

 Score =  190 bits (483), Expect = 1e-48
 Identities = 108/254 (42%), Positives = 138/254 (54%), Gaps = 15/254 (5%)

Query: 30  SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89
           S  CG RV  SR++GG  A   +WPWQ SL+  + H CG SL+  RW LTAAHC      
Sbjct: 153 SQACGHRV--SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC------ 204

Query: 90  LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTY 149
           +    GW      L  +   W  QA+  ++    I+ S         DIAL  L+  V Y
Sbjct: 205 VFRGCGWEGGRWLLAGIGR-WD-QAW--KHLEDIIFPSNFDFATLTSDIALALLAYSVNY 260

Query: 150 TKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFL 209
           + HIQP CL    FE E  T+CWVTGWG + E  + P P  LQE ++ I+ +  C  +  
Sbjct: 261 SSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLK 320

Query: 210 KYSFRKD--IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNR 267
             +  K   +    VC  N QG KDAC GDSGGPL C  NG W Q+G+VSWG+GCGR   
Sbjct: 321 NKNISKSKMVTRGTVCGYNDQG-KDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGY 379

Query: 268 PGVYTNISHHFEWI 281
           PGVYT +S + +WI
Sbjct: 380 PGVYTEVSFYKKWI 393


>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
           sapiens]
          Length = 410

 Score =  190 bits (483), Expect = 1e-48
 Identities = 108/254 (42%), Positives = 138/254 (54%), Gaps = 15/254 (5%)

Query: 30  SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89
           S  CG RV  SR++GG  A   +WPWQ SL+  + H CG SL+  RW LTAAHC      
Sbjct: 153 SQACGHRV--SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC------ 204

Query: 90  LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTY 149
           +    GW      L  +   W  QA+  ++    I+ S         DIAL  L+  V Y
Sbjct: 205 VFRGCGWEGGRWLLAGIGR-WD-QAW--KHLEDIIFPSNFDFATLTSDIALALLAYSVNY 260

Query: 150 TKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFL 209
           + HIQP CL    FE E  T+CWVTGWG + E  + P P  LQE ++ I+ +  C  +  
Sbjct: 261 SSHIQPACLPEKLFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLK 320

Query: 210 KYSFRKD--IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNR 267
             +  K   +    VC  N QG KDAC GDSGGPL C  NG W Q+G+VSWG+GCGR   
Sbjct: 321 NKNISKSKMVTRGTVCGYNDQG-KDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGY 379

Query: 268 PGVYTNISHHFEWI 281
           PGVYT +S + +WI
Sbjct: 380 PGVYTEVSFYKKWI 393


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  188 bits (477), Expect = 6e-48
 Identities = 109/284 (38%), Positives = 157/284 (55%), Gaps = 25/284 (8%)

Query: 7   LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHV 66
           +LL L+L  AG +  +S         CG+  ++SRIVGG D   G WPWQ S++   +HV
Sbjct: 9   VLLLLVLGAAGTQGRKS-------AACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHV 61

Query: 67  CGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQL---TSMPSFWSLQAYYTRYFVSN 123
           CG SL++ +W LTAAHCF   +    P+ + V+ G L   ++ P   S+        V  
Sbjct: 62  CGGSLIAPQWVLTAAHCFPRRAL---PAEYRVRLGALRLGSTSPRTLSVP-------VRR 111

Query: 124 IYLSPRYLGNSPY-DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182
           + L P Y  +    D+AL++L  PV  +  +QP+CL          T C VTGWG ++  
Sbjct: 112 VLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPG 171

Query: 183 EALPSPHTLQEVQVAIINNSMCNHLFLKYS----FRKDIFGDMVCAGNAQGGKDACFGDS 238
             LP    LQ V+V ++++  C+ L+   +      + +    +CAG  QG KDAC GDS
Sbjct: 172 VPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDS 231

Query: 239 GGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ 282
           GGPL C ++G W  +GVVSWG GC  PNRPGVYT+++ +  WIQ
Sbjct: 232 GGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQ 275


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  186 bits (473), Expect = 2e-47
 Identities = 106/256 (41%), Positives = 148/256 (57%), Gaps = 18/256 (7%)

Query: 30  SGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89
           +GP    +   RI+GG +AE G WPWQ SLRL ++H CG SL+++ W LTAAHCF +   
Sbjct: 175 AGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN-- 232

Query: 90  LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVT 148
            S+P  W+   G  T+ P          R  V NI +   Y       DIALV+L   VT
Sbjct: 233 -SNPRDWIATSGISTTFPKL--------RMRVRNILIHNNYKSATHENDIALVRLENSVT 283

Query: 149 YTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLF 208
           +TK I  +CL A+T      +  +VTGWG   ++ A  +   L++ QV II+N +CN   
Sbjct: 284 FTKDIHSVCLPAATQNIPPGSTAYVTGWG--AQEYAGHTVPELRQGQVRIISNDVCN--- 338

Query: 209 LKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC-NKNGLWYQIGVVSWGVGCGRPNR 267
             +S+   I   M+CAG  QGG DAC GDSGGPL   +   LW+ +G+VSWG  CG P++
Sbjct: 339 APHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDK 398

Query: 268 PGVYTNISHHFEWIQK 283
           PGVYT ++ + +WI++
Sbjct: 399 PGVYTRVTAYLDWIRQ 414


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  184 bits (466), Expect = 1e-46
 Identities = 97/273 (35%), Positives = 150/273 (54%), Gaps = 25/273 (9%)

Query: 38  ITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWM 97
           +  RIVGG +A  G +PWQ SLR    H CG ++++ RW ++AAHCF   ++  DP+ W+
Sbjct: 199 MAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCF---NEFQDPTKWV 255

Query: 98  VQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVTYTKHIQPI 156
              G      S    +A   R  V  I   P Y    + +D+A+++L++P+ + +HIQP+
Sbjct: 256 AYVGATYLSGS----EASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPV 311

Query: 157 CLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKD 216
           CL A+T  F     C ++GWGY+KED  L  P  LQ+  V +++ ++C  L     +   
Sbjct: 312 CLPAATHIFPPSKKCLISGWGYLKED-FLVKPEVLQKATVELLDQALCASL-----YGHS 365

Query: 217 IFGDMVCAGNAQGGKDACFGDSGGPLACNK-NGLWYQIGVVSWGVGCGRPNRPGVYTNIS 275
           +   MVCAG   G  D+C GDSGGPL C + +G ++  G+VSWG+GC    RPGVY  ++
Sbjct: 366 LTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVT 425

Query: 276 HHFEWIQKLMAQSGM----------SQPDPSWP 298
              +WI +   ++ M          + P  +WP
Sbjct: 426 RLRDWILEATTKASMPLAPTMAPAPAAPSTAWP 458



 Score =  169 bits (427), Expect = 4e-42
 Identities = 98/245 (40%), Positives = 132/245 (53%), Gaps = 19/245 (7%)

Query: 40   SRIVGGEDAELGRWPWQGSLRLWD-SHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMV 98
            +RIVGG  A  G WPWQ SL L    H CG  L++ RW L+AAHCF+ Y D   P  W  
Sbjct: 825  TRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGD---PKQWAA 881

Query: 99   QFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVTYTKHIQPIC 157
              G     P     +    R  V+ IY  P Y L    YD+AL++L+ PV  ++ ++PIC
Sbjct: 882  FLGT----PFLSGAEGQLER--VARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPIC 935

Query: 158  LQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDI 217
            L        + T C +TGWG ++E  ++     LQ+  V +++   C   +        I
Sbjct: 936  LPEPAPRPPDGTRCVITGWGSVREGGSMA--RQLQKAAVRLLSEQTCRRFY-----PVQI 988

Query: 218  FGDMVCAGNAQGGKDACFGDSGGPLACNK-NGLWYQIGVVSWGVGCGRPNRPGVYTNISH 276
               M+CAG  QGG D+C GD+GGPLAC + +G W   GV SWG GCGRP+ PGVYT ++ 
Sbjct: 989  SSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAA 1048

Query: 277  HFEWI 281
               WI
Sbjct: 1049 VRGWI 1053



 Score =  164 bits (414), Expect = 1e-40
 Identities = 95/269 (35%), Positives = 142/269 (52%), Gaps = 19/269 (7%)

Query: 33  CGRRVIT---SRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSD 89
           CG R      +R+VGG  A  G  PWQ SL+    H CG +++  RW L+AAHCF     
Sbjct: 492 CGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTK- 550

Query: 90  LSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVT 148
                  + Q        S   L     +  +  + L P Y  G   +D+A+++L++P+ 
Sbjct: 551 -------VEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLA 603

Query: 149 YTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLF 208
           + K+IQP+CL  +  +F     C ++GWG  +E  A   P  LQ+  V II+   C+ L 
Sbjct: 604 FNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNA-TKPELLQKASVGIIDQKTCSVL- 661

Query: 209 LKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNK-NGLWYQIGVVSWGVGCGRPNR 267
             Y+F   +   M+CAG  +G  D+C GDSGGPLAC +  G++Y  G+VSWG+GC +  +
Sbjct: 662 --YNF--SLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKK 717

Query: 268 PGVYTNISHHFEWIQKLMAQSGMSQPDPS 296
           PGVYT I+    WI ++M+   +    PS
Sbjct: 718 PGVYTRITRLKGWILEIMSSQPLPMSPPS 746


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  183 bits (464), Expect = 2e-46
 Identities = 101/251 (40%), Positives = 141/251 (56%), Gaps = 23/251 (9%)

Query: 38  ITSRIVGGEDAELGRWPWQGSLRLWDS---HVCGVSLLSHRWALTAAHCF---ETYSDLS 91
           I  RIVGG  +  G WPWQ +L        H+CG S++ ++W LTAAHCF   E+   L 
Sbjct: 384 IKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILR 443

Query: 92  DPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVTYT 150
             SG + Q  ++    SF+ +Q          I +  +Y +  S YDIAL+KL   V YT
Sbjct: 444 VYSGILNQ-SEIKEDTSFFGVQ---------EIIIHDQYKMAESGYDIALLKLETTVNYT 493

Query: 151 KHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK 210
              +PICL +        TDCWVTGWGY K  + + +  TLQ+ ++ ++ N  C   +  
Sbjct: 494 DSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQN--TLQKAKIPLVTNEECQKRYRG 551

Query: 211 YSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGV 270
           +     I   M+CAG  +GGKDAC GDSGGPL+C  N +W+ +G+ SWG GC +  RPGV
Sbjct: 552 HK----ITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGV 607

Query: 271 YTNISHHFEWI 281
           YTN+  + +WI
Sbjct: 608 YTNVVEYVDWI 618


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score =  182 bits (461), Expect = 4e-46
 Identities = 98/251 (39%), Positives = 146/251 (58%), Gaps = 19/251 (7%)

Query: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
           CG+ + T R+VGGE+A +  WPWQ S++    HVCG S+L   W LTAAHCF  ++D+ +
Sbjct: 191 CGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFN 250

Query: 93  PSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYT 150
              W V+ G  +L S PS    +       +  I  +P Y  ++  DIAL+KL  P+T++
Sbjct: 251 ---WKVRAGSDKLGSFPSLAVAK-------IIIIEFNPMYPKDN--DIALMKLQFPLTFS 298

Query: 151 KHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK 210
             ++PICL     E    T  W+ GWG+ K++    S   LQ   V +I+++ CN     
Sbjct: 299 GTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQ-ASVQVIDSTRCN---AD 354

Query: 211 YSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGV 270
            +++ ++   M+CAG  +GG D C GDSGGPL   ++  W+ +G+VSWG GCG P+ PGV
Sbjct: 355 DAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPL-MYQSDQWHVVGIVSWGYGCGGPSTPGV 413

Query: 271 YTNISHHFEWI 281
           YT +S +  WI
Sbjct: 414 YTKVSAYLNWI 424


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score =  182 bits (461), Expect = 4e-46
 Identities = 98/251 (39%), Positives = 146/251 (58%), Gaps = 19/251 (7%)

Query: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
           CG+ + T R+VGGE+A +  WPWQ S++    HVCG S+L   W LTAAHCF  ++D+ +
Sbjct: 196 CGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFN 255

Query: 93  PSGWMVQFG--QLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYT 150
              W V+ G  +L S PS    +       +  I  +P Y  ++  DIAL+KL  P+T++
Sbjct: 256 ---WKVRAGSDKLGSFPSLAVAK-------IIIIEFNPMYPKDN--DIALMKLQFPLTFS 303

Query: 151 KHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK 210
             ++PICL     E    T  W+ GWG+ K++    S   LQ   V +I+++ CN     
Sbjct: 304 GTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQ-ASVQVIDSTRCN---AD 359

Query: 211 YSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGV 270
            +++ ++   M+CAG  +GG D C GDSGGPL   ++  W+ +G+VSWG GCG P+ PGV
Sbjct: 360 DAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPL-MYQSDQWHVVGIVSWGYGCGGPSTPGV 418

Query: 271 YTNISHHFEWI 281
           YT +S +  WI
Sbjct: 419 YTKVSAYLNWI 429


>gi|33186882 testis serine protease 2 [Homo sapiens]
          Length = 293

 Score =  179 bits (454), Expect = 3e-45
 Identities = 108/269 (40%), Positives = 142/269 (52%), Gaps = 28/269 (10%)

Query: 12  LLARAGLRKPESQEA-APLSGP--------------CGRRVITSRIVGGEDAELGRWPWQ 56
           LL+  G   PE+  A  P +GP              CGR  +  RIVGG DAE GRWPWQ
Sbjct: 37  LLSEEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPL--RIVGGVDAEEGRWPWQ 94

Query: 57  GSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYY 116
            S+R    H+CG +L++  W LTA HC      +S    + V+ G  +      S+    
Sbjct: 95  VSVRTKGRHICGGTLVTATWVLTAGHC------ISSRFHYSVKMGDRSVYNENTSVVVSV 148

Query: 117 TRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGW 176
            R FV   + +   + N   D+AL++L  PV +T +IQPIC+    F+ E RT CWVTGW
Sbjct: 149 QRAFVHPKFSTVTTIRN---DLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGW 205

Query: 177 GYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK-YSFRKDIFGDMVCAGNAQGGKDACF 235
           G   E E L S   LQ+V   I+    CN +  K  S  KD+    +  G  + GKD+C 
Sbjct: 206 GKTPEREKLAS-EILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQ 264

Query: 236 GDSGGPLACNKNGLWYQIGVVSWGVGCGR 264
           GDSGG LAC  N  W Q+G+VSWG+GCGR
Sbjct: 265 GDSGGRLACEYNDTWVQVGIVSWGIGCGR 293


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score =  179 bits (453), Expect = 4e-45
 Identities = 97/242 (40%), Positives = 142/242 (58%), Gaps = 16/242 (6%)

Query: 41  RIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQF 100
           RIVGG + E G WPWQ SL+   SH CG +L++  W ++AAHCF TY    +P+ W   F
Sbjct: 191 RIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTY---KNPARWTASF 247

Query: 101 GQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQA 160
           G +T  PS   ++    R  V   Y  P +     YDI+L +LS+PV YT  +  +CL  
Sbjct: 248 G-VTIKPS--KMKRGLRRIIVHEKYKHPSH----DYDISLAELSSPVPYTNAVHRVCLPD 300

Query: 161 STFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGD 220
           +++EF+     +VTG+G +K D    S + L++ QV +I+ + CN      ++   I   
Sbjct: 301 ASYEFQPGDVMFVTGFGALKNDGY--SQNHLRQAQVTLIDATTCNE---PQAYNDAITPR 355

Query: 221 MVCAGNAQGGKDACFGDSGGPL-ACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFE 279
           M+CAG+ +G  DAC GDSGGPL + +   +WY  G+VSWG  C +PN+PGVYT ++   +
Sbjct: 356 MLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRD 415

Query: 280 WI 281
           WI
Sbjct: 416 WI 417


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  179 bits (453), Expect = 4e-45
 Identities = 94/250 (37%), Positives = 129/250 (51%), Gaps = 11/250 (4%)

Query: 33  CGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSD 92
           CG R + SRIVGG+    GRWPWQ S+ L   H CG S+L+ RW +TAAHC  ++  L+ 
Sbjct: 209 CGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFR-LAR 267

Query: 93  PSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLG-NSPYDIALVKLSAPVTYTK 151
            S W V  G ++      S    +    V  I   P Y   N  YD+AL++L   + ++ 
Sbjct: 268 LSSWRVHAGLVSH-----SAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSD 322

Query: 152 HIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211
            +  +CL A    F   + CWV+GWG+        S   LQ+  V + +  +CN   +  
Sbjct: 323 TVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSD-MLQDTVVPLFSTQLCNSSCV-- 379

Query: 212 SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVY 271
            +   +   M+CAG   G  DAC GDSGGPL C     W  +GVVSWG GC  PN PGVY
Sbjct: 380 -YSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVY 438

Query: 272 TNISHHFEWI 281
             ++   +WI
Sbjct: 439 AKVAEFLDWI 448


>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
          Length = 423

 Score =  179 bits (453), Expect = 4e-45
 Identities = 97/242 (40%), Positives = 142/242 (58%), Gaps = 16/242 (6%)

Query: 41  RIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQF 100
           RIVGG + E G WPWQ SL+   SH CG +L++  W ++AAHCF TY    +P+ W   F
Sbjct: 191 RIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTY---KNPARWTASF 247

Query: 101 GQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQA 160
           G +T  PS   ++    R  V   Y  P +     YDI+L +LS+PV YT  +  +CL  
Sbjct: 248 G-VTIKPS--KMKRGLRRIIVHEKYKHPSH----DYDISLAELSSPVPYTNAVHRVCLPD 300

Query: 161 STFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGD 220
           +++EF+     +VTG+G +K D    S + L++ QV +I+ + CN      ++   I   
Sbjct: 301 ASYEFQPGDVMFVTGFGALKNDGY--SQNHLRQAQVTLIDATTCNE---PQAYNDAITPR 355

Query: 221 MVCAGNAQGGKDACFGDSGGPL-ACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFE 279
           M+CAG+ +G  DAC GDSGGPL + +   +WY  G+VSWG  C +PN+PGVYT ++   +
Sbjct: 356 MLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRD 415

Query: 280 WI 281
           WI
Sbjct: 416 WI 417


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  177 bits (450), Expect = 8e-45
 Identities = 114/272 (41%), Positives = 141/272 (51%), Gaps = 23/272 (8%)

Query: 21  PESQEAAPLSGPCGRRVI-TSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSLLSHRWALT 79
           P  +  A +   CGRR +   RIVGG D  LGRWPWQ SLR   +H+CG SLLS  W LT
Sbjct: 141 PRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLT 200

Query: 80  AAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYL---SPRYLGNSPY 136
           AAHCF   + +   S W V F    +  S   LQ           YL    P    NS  
Sbjct: 201 AAHCFPERNRVL--SRWRV-FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENS-N 256

Query: 137 DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWG---YIKEDEALPSPHTLQE 193
           DIALV LS+P+  T++IQP+CL A+     +   C VTGWG   Y  +   +     LQE
Sbjct: 257 DIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-----LQE 311

Query: 194 VQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC----NKNGL 249
            +V II+N +CN       +   I   M CAG  +GG DAC GDSGGP  C    ++   
Sbjct: 312 ARVPIISNDVCNGADF---YGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPR 368

Query: 250 WYQIGVVSWGVGCGRPNRPGVYTNISHHFEWI 281
           W   G+VSWG GC    +PGVYT +S   EWI
Sbjct: 369 WRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.467 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,557,975
Number of Sequences: 37866
Number of extensions: 641679
Number of successful extensions: 1857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1212
Number of HSP's gapped (non-prelim): 219
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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