Guide to the Human Genome
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Search of human proteins with 57863269

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57863269 ribosomal RNA processing 1 homolog B [Homo sapiens]
         (758 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57863269 ribosomal RNA processing 1 homolog B [Homo sapiens]      1512   0.0  
gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens]          391   e-108
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         51   5e-06
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       50   6e-06
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       50   6e-06
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]                       45   2e-04
gi|49472835 bridging integrator 2 [Homo sapiens]                       45   3e-04
gi|6912246 CD3E antigen, epsilon polypeptide associated protein ...    44   4e-04
gi|33457316 pleckstrin homology domain containing, family O memb...    43   0.001
gi|122937223 NOBOX oogenesis homeobox [Homo sapiens]                   42   0.002
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    42   0.002
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    42   0.002
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    42   0.002
gi|50962882 G patch domain containing 8 [Homo sapiens]                 42   0.002
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...    42   0.003
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             42   0.003
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    41   0.004
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  41   0.005
gi|50428935 BPY2 interacting protein 1 [Homo sapiens]                  41   0.005
gi|163965366 nascent polypeptide-associated complex alpha subuni...    41   0.005
gi|98991767 mitogen-activated protein kinase kinase kinase 7 int...    40   0.006
gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo...    40   0.008
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]          40   0.008
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]          40   0.008
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]          40   0.008
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]          40   0.008
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]          40   0.008
gi|221316599 chromogranin B precursor [Homo sapiens]                   40   0.010
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]       40   0.010
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             40   0.010

>gi|57863269 ribosomal RNA processing 1 homolog B [Homo sapiens]
          Length = 758

 Score = 1512 bits (3915), Expect = 0.0
 Identities = 758/758 (100%), Positives = 758/758 (100%)

Query: 1   MAPAMQPAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFY 60
           MAPAMQPAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFY
Sbjct: 1   MAPAMQPAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFY 60

Query: 61  CMWVQDEPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYML 120
           CMWVQDEPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYML
Sbjct: 61  CMWVQDEPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYML 120

Query: 121 IRLVLRQSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVG 180
           IRLVLRQSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVG
Sbjct: 121 IRLVLRQSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVG 180

Query: 181 GKELLADQNLKFIDPFCKIAAKTKDHTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVG 240
           GKELLADQNLKFIDPFCKIAAKTKDHTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVG
Sbjct: 181 GKELLADQNLKFIDPFCKIAAKTKDHTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVG 240

Query: 241 DGDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDY 300
           DGDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDY
Sbjct: 241 DGDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDY 300

Query: 301 KAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQ 360
           KAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQ
Sbjct: 301 KAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQ 360

Query: 361 GKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAA 420
           GKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAA
Sbjct: 361 GKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAA 420

Query: 421 PSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSP 480
           PSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSP
Sbjct: 421 PSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSP 480

Query: 481 RAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTP 540
           RAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTP
Sbjct: 481 RAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTP 540

Query: 541 AWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMR 600
           AWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMR
Sbjct: 541 AWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMR 600

Query: 601 VMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKPLFFRRAK 660
           VMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKPLFFRRAK
Sbjct: 601 VMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKPLFFRRAK 660

Query: 661 SSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFDPEQK 720
           SSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFDPEQK
Sbjct: 661 SSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFDPEQK 720

Query: 721 PLHGVLKTPTSSPASSPLVAKKPLTTTPRRRPRAMDFF 758
           PLHGVLKTPTSSPASSPLVAKKPLTTTPRRRPRAMDFF
Sbjct: 721 PLHGVLKTPTSSPASSPLVAKKPLTTTPRRRPRAMDFF 758


>gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens]
          Length = 461

 Score =  391 bits (1004), Expect = e-108
 Identities = 215/471 (45%), Positives = 298/471 (63%), Gaps = 22/471 (4%)

Query: 7   PAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFYCMWVQD 66
           P EIQ AQRLA +E+  RDRAV+KLR+YI  +TQR  GGF+ +ELLK+WKGLFYCMW+QD
Sbjct: 8   PPEIQLAQRLAGNEQVTRDRAVRKLRKYIVARTQRAAGGFTHDELLKVWKGLFYCMWMQD 67

Query: 67  EPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYMLIRLVLR 126
           +PLLQEEL  TI+QLVHA   + AQHLF+Q FWQTMNREW GIDRLRLDK+YML+R+VL 
Sbjct: 68  KPLLQEELGRTISQLVHAFQTTEAQHLFLQAFWQTMNREWTGIDRLRLDKFYMLMRMVLN 127

Query: 127 QSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVGGKELLA 186
           +S +VLK  GWEE +I+  L++LM E+L P SQ+PNGV+ HFI+I+L+EL+KVG +EL A
Sbjct: 128 ESLKVLKMQGWEERQIEELLELLMTEILHPSSQAPNGVKSHFIEIFLEELTKVGAEELTA 187

Query: 187 DQNLKFIDPFCKIAAKTKDHTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVGDGDLSA 246
           DQNLKFIDPFC+IAA+TKD  ++  I RG+FE IV+Q+P   E+ + E  T+  D ++++
Sbjct: 188 DQNLKFIDPFCRIAARTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQ--DEEVAS 245

Query: 247 EEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDT-GPLLQFDYKAVAD 305
           +    +E   R     +K +             E G +  G   D+ GP+LQFDY+AVA+
Sbjct: 246 DSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVAN 305

Query: 306 RLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQGKHKK 365
           RL EM SR++TP  NRKRL K+I+K QDL+ G       F ED   ++  + L +G+ +K
Sbjct: 306 RLFEMASRQSTPSQNRKRLYKVIRKLQDLAGG------IFPEDEIPEKACRRLLEGRRQK 359

Query: 366 KGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQ 425
           K  K      L++E+G       E++  S   +R+R +++     PE     G  P   +
Sbjct: 360 KTKKQKRLLRLQQERGK-----GEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAE 414

Query: 426 NR--GREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKR 474
                 +P   G +  + R   P    TS+  + +  + P       K+KR
Sbjct: 415 RALLRDQPRGRGQRGARQRRRTP-RPLTSARAKAANVQEP-----EKKKKR 459


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 91/469 (19%), Positives = 150/469 (31%), Gaps = 54/469 (11%)

Query: 313 RKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQGKHKKKGNKLLE 372
           ++ TP      +       Q+ +  S I ++   E I   ++       K +K+  K   
Sbjct: 217 KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRP 276

Query: 373 KTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPEN-------PGPGGAAPSLEQ 425
           ++    +  SR        S S  + RRR + +     P         P P    P    
Sbjct: 277 RSRSRSKSRSRT----RSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332

Query: 426 NRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHRE 485
                   S     + R +      +SS+   S S  PP  P       PRK        
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT------R 386

Query: 486 MLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPL 545
            L  +  PP    +  P  + P   R SPT       RK ++ V P   SG  T      
Sbjct: 387 RLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTE 446

Query: 546 QQEGPPTGPA------------EGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASL 593
           ++E P   P             +G         ++R Q ++    S    G  S      
Sbjct: 447 KRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER 506

Query: 594 KKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKP 653
            KR  ++        NG    E G+ +    S + S   +++ +  S   +      P P
Sbjct: 507 PKRSHVK--------NG----EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPP 554

Query: 654 LFFRRAKS--------STATHPP---GPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKS 702
              RR+ S         T T PP    P+    +   S ++ +  + R  +       K 
Sbjct: 555 TRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP--SPPPKR 612

Query: 703 ILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPASSPLVAKKPLTTTPRRR 751
              SP  P +    P   P   V  +P     SSP+  ++  + + + R
Sbjct: 613 RTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHR 661



 Score = 33.1 bits (74), Expect = 0.98
 Identities = 61/319 (19%), Positives = 97/319 (30%), Gaps = 73/319 (22%)

Query: 369 KLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQNRG 428
           KL      +++K  R    ++E+ ESS +KR R +  +   +  +P P   +  + + R 
Sbjct: 140 KLASMKKQDEDKDKR----DKEEKESSREKRERSRSPRRR-KSRSPSPRRRSSPVRRERK 194

Query: 429 REPEASGLKALKARVA-------------------------------------------- 444
           R    S     K+R                                              
Sbjct: 195 RSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIP 254

Query: 445 ---EPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSP------RAHREMLESAVLPPE 495
              EP  E  S   +E     P +      R R R +SP      R HR    S      
Sbjct: 255 EPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR 314

Query: 496 DMSQSGPSGSHPQGPRGSPT----GGAQLLKRKRKLGVVPVNGSGLST--------PAWP 543
              +  PS      PR  P       ++   R+R+     ++GS  S+        P  P
Sbjct: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374

Query: 544 PLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKM---R 600
           P +   PP      + S +   +R R       P        P Q   + K R  +   R
Sbjct: 375 PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434

Query: 601 VMSNLVEHNGVLESEAGQP 619
               + +H G  + E+  P
Sbjct: 435 TSGKVTKHKGTEKRESPSP 453


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 44/157 (28%), Positives = 59/157 (37%), Gaps = 32/157 (20%)

Query: 411 PENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHN 470
           P+ P    A P+  Q R   P A G          PGA   +          PPA P   
Sbjct: 515 PQQPASQAAPPTQGQGRQSRPVAGG----------PGAPPAA---------RPPASPSPQ 555

Query: 471 KRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVV 530
           ++  P    P+A R+   S   PP+  S + P G   QGP   P G A   ++  + G V
Sbjct: 556 RQAGP----PQATRQTSVSGPAPPK-ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV 610

Query: 531 PVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQR 567
           P  G        PP  Q+  P+GP         L Q+
Sbjct: 611 PRTG--------PPTTQQPRPSGPGPAGRPKPQLAQK 639



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 34/110 (30%), Positives = 43/110 (39%), Gaps = 25/110 (22%)

Query: 492 LPPEDMSQSGPS-GSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQEGP 550
           LP +    + P  GSH Q P  SP             G +P+       PA PP QQ  P
Sbjct: 418 LPRQRQRDASPGRGSHGQTP--SP-------------GALPLGRQTSQQPAGPPAQQRPP 462

Query: 551 PTG--PAEGANSHTTLPQRR--RLQKKKAGPGSLELCGLPSQKTASLKKR 596
           P G  P  G       PQR+   LQ++    G   L GL     + L +R
Sbjct: 463 PQGGPPQPGPG-----PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQR 507


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 44/157 (28%), Positives = 59/157 (37%), Gaps = 32/157 (20%)

Query: 411 PENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHN 470
           P+ P    A P+  Q R   P A G          PGA   +          PPA P   
Sbjct: 515 PQQPASQAAPPTQGQGRQSRPVAGG----------PGAPPAA---------RPPASPSPQ 555

Query: 471 KRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVV 530
           ++  P    P+A R+   S   PP+  S + P G   QGP   P G A   ++  + G V
Sbjct: 556 RQAGP----PQATRQTSVSGPAPPK-ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV 610

Query: 531 PVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQR 567
           P  G        PP  Q+  P+GP         L Q+
Sbjct: 611 PRTG--------PPTTQQPRPSGPGPAGRPKPQLAQK 639



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 34/110 (30%), Positives = 43/110 (39%), Gaps = 25/110 (22%)

Query: 492 LPPEDMSQSGPS-GSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQEGP 550
           LP +    + P  GSH Q P  SP             G +P+       PA PP QQ  P
Sbjct: 418 LPRQRQRDASPGRGSHGQTP--SP-------------GALPLGRQTSQQPAGPPAQQRPP 462

Query: 551 PTG--PAEGANSHTTLPQRR--RLQKKKAGPGSLELCGLPSQKTASLKKR 596
           P G  P  G       PQR+   LQ++    G   L GL     + L +R
Sbjct: 463 PQGGPPQPGPG-----PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQR 507


>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 64/294 (21%), Positives = 112/294 (38%), Gaps = 32/294 (10%)

Query: 289  FEDTGPLLQFDYKAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSE--GSSISQLSFA 346
            F++T  +    YKA+   LLE T +       ++   +  +K   L+E    SIS++  +
Sbjct: 754  FQETCKIQTRQYKALRAHLLETTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSS 813

Query: 347  EDISADEDDQILSQGKHKKKG----------NKLLEKTNLEKEKGSRVFCVEEEDSESSL 396
            + +  DE  +   Q   ++            +K+  +T  + E+  R     E +   +L
Sbjct: 814  QALRLDETQEAEFQALRQQLQQELELLNAYQSKIKIRTESQHERELR-----ELEQRVAL 868

Query: 397  QKRRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGE 456
            ++   +++ +  L     G      SL + + RE EA   ++++   +        +   
Sbjct: 869  RRALLEQRVEEELLALQTGRSERIRSLLERQAREIEAFDAESMRLGFSSMALGGIPAEAA 928

Query: 457  ESGSEHPPAVPMHNKRKRPRKKSPRAHRE----MLESAVLPPEDMSQSG-PSGSHPQGPR 511
              G   PP  P    R  PR  +  +H      M   A   P  ++  G P+   P    
Sbjct: 929  AQGYPAPPPAPAWPSRPVPRSGAHWSHGPPPPGMPPPAWRQPSLLAPPGPPNWLGPPTQS 988

Query: 512  GSPTGGAQLLKRK--RKLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTT 563
            G+P GGA LL R   + L      GSG         +  GPP     G  S +T
Sbjct: 989  GTPRGGALLLLRNSPQPLRRAASGGSG--------SENVGPPAAAVPGPLSRST 1034


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 51/188 (27%), Positives = 78/188 (41%), Gaps = 30/188 (15%)

Query: 338 SSISQLSFAEDISADED-DQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEED----- 391
           S++S  S +E +SA ED     +QG+   +  +LLE+  +EKE GS     EE++     
Sbjct: 282 STLSLKSESESVSATEDLAPDAAQGEDNSEIKELLEEEEIEKE-GSEASSSEEDEPLPAC 340

Query: 392 -----SESSLQKRRRKKKKKHHLQPENPGPGGA-APSLEQNRGREPEASGLKALKARVAE 445
                ++ S    R K +++       P PGGA +PS     G+   ++    L+ R A 
Sbjct: 341 NGPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPS-----GQPSSSATEVVLRTRTAS 395

Query: 446 PGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGS 505
            G+E          +  PP+          R   PRA      S+   P   + SG  G 
Sbjct: 396 EGSEQPKKRASIQRTSAPPS----------RPPPPRATASPRPSSGNIPSSPTASG--GG 443

Query: 506 HPQGPRGS 513
            P  PR S
Sbjct: 444 SPTSPRAS 451


>gi|6912246 CD3E antigen, epsilon polypeptide associated protein
           [Homo sapiens]
          Length = 510

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 71/308 (23%), Positives = 112/308 (36%), Gaps = 40/308 (12%)

Query: 357 ILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHL-QPENPG 415
           +L+ GK KK+          E   G     V+       +  R++KKKK   L +PE  G
Sbjct: 169 LLTSGKKKKEMQVTEAPVTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAG 228

Query: 416 PGGAAPSLEQNRGREPEASGL---KALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKR 472
           P G  P++E       E  G+      K R    G E      +    E     P+ +  
Sbjct: 229 PVGTEPTVE-----TLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQINTEPLEDTV 283

Query: 473 KRPRKKSPRAHREMLESAVLPPEDMS-QSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVP 531
             P KK     R+     + P E ++ +S P           P    +  KRK++ G + 
Sbjct: 284 LSPTKK---RKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTK--KRKKEKGQMA 338

Query: 532 VNGSGLST-----PAWPPLQQEG------PPTGPAEGANSHTTLPQRRRLQKKK------ 574
           +   G        P   PL+  G       P G    A +    P+++  ++K+      
Sbjct: 339 MMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKEKQQDATVE 398

Query: 575 -----AGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESE---AGQPQALGSSG 626
                 GP   +     +  T++ KK+KK      + E    LE E    GQP+A  + G
Sbjct: 399 PETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPG 458

Query: 627 TCSSLKKQ 634
           +    KKQ
Sbjct: 459 STKKRKKQ 466



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 68/322 (21%), Positives = 126/322 (39%), Gaps = 41/322 (12%)

Query: 308 LEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQIL----SQGKH 363
           LE+     +P  + ++  K  KK Q L E  +   +     +   E   +L    ++ + 
Sbjct: 197 LEVDMALGSPEMDVRKKKK--KKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRK 254

Query: 364 KKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSL 423
           K KG +  E  + +  K  ++     ED+  S  K+R+++K    ++PE      + P +
Sbjct: 255 KPKGKETFEPED-KTVKQEQINTEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQV 313

Query: 424 EQNRGRE----PEASGLKALKARVA--EPGAEATSSTGEESGSEHPPA---VPMHNKRKR 474
           +     E    P     K  K ++A  EPG EA      E      P     P   +  +
Sbjct: 314 KVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAK 373

Query: 475 PRKKS------PRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLG 528
           P+ ++       +  +E  + A + PE     GP       P+ +PT   +  K+K +  
Sbjct: 374 PQAQAALAAPKKKTKKEKQQDATVEPE-TEVVGPELPDDLEPQAAPTSTKKKKKKKER-- 430

Query: 529 VVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSL---ELCGL 585
                G  ++ P   PL+ E P  G  E   +  +  +R++  ++   P ++   E+ G 
Sbjct: 431 -----GHTVTEPI-QPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGP 484

Query: 586 P-------SQKTASLKKRKKMR 600
           P          T   KKRK+ +
Sbjct: 485 PLNSESGEEAPTGRDKKRKQQQ 506


>gi|33457316 pleckstrin homology domain containing, family O member
           2 [Homo sapiens]
          Length = 490

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 51/204 (25%), Positives = 73/204 (35%), Gaps = 23/204 (11%)

Query: 379 EKGSRVFCVEEEDSESSLQKRRRK--KKKKHHLQPENPGPGGAAPSLEQNRGREPEASGL 436
           + G  VF      SE+  ++  R      K  L PE   PG    +    R   P ++  
Sbjct: 179 DSGPPVFAPSNHVSEAQPRETPRPLMPPTKPFLAPETTSPGDRVETPVGERAPTPVSASS 238

Query: 437 KALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPED 496
           +       E   ++ +   E+SGSE PP   + +K K   +          ESA   P  
Sbjct: 239 EVSP----ESQEDSETPAEEDSGSEQPPNSVLPDKLKVSWENPSPQEAPAAESA--EPSQ 292

Query: 497 MSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGV---------------VPVNGSGLSTPA 541
              S  S + P+     PT   ++L  K K  +               V VNG   S   
Sbjct: 293 APCSETSEAAPREGGKPPTPPPKILSEKLKASMGEMQASGPPAPGTVQVSVNGMDDSPEP 352

Query: 542 WPPLQQEGPPTGPAEGANSHTTLP 565
             P Q EG P  P + A + T LP
Sbjct: 353 AKPSQAEGTPGTPPKDATTSTALP 376


>gi|122937223 NOBOX oogenesis homeobox [Homo sapiens]
          Length = 490

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 56/230 (24%), Positives = 94/230 (40%), Gaps = 33/230 (14%)

Query: 398 KRRRKKKKKHHLQPENPGPG------GAAPSLEQNRGRE-PEASGLKALKARVAEPGAEA 450
           KR   + +K   +P   GPG      G+AP  +  +  E P +  +   K    +P A +
Sbjct: 92  KRELTRGQKAGEKPLAAGPGEEELLRGSAPHAQDTQSEELPPSCTISGEK----KPPAVS 147

Query: 451 TSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQ--SGPSGSHPQ 508
             +TG ++G   PP          PR ++P   R +  S    P+   +  S P G    
Sbjct: 148 GEATGADAGRLCPP----------PRSRAPHKDRTLARSR---PQTQGEDCSLPVGEVKI 194

Query: 509 GPRG-SPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQE--GPPTGPAEGANSHTTLP 565
           G R  SP  G Q  K+   +G+ P +  G    A         G   GP   AN  +TL 
Sbjct: 195 GKRSYSPAPGKQ--KKPNAMGLAPTSSPGAPNSARATHNPVPCGSGRGPCHLANLLSTLA 252

Query: 566 QRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESE 615
           Q  + +  K GP  +  C +  +KT +L +  ++  +  + + +   +S+
Sbjct: 253 QSNQNRDHKQGPPEV-TCQI-RKKTRTLYRSDQLEELEKIFQEDHYPDSD 300


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 66/280 (23%), Positives = 96/280 (34%), Gaps = 42/280 (15%)

Query: 399  RRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEES 458
            R+ +K  K     E P PG   P   Q    +P   GL+ +   V E G    +      
Sbjct: 1385 RQGEKGAKGEAGAEGP-PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443

Query: 459  GSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGA 518
            G   PP +P    +  P  K  + H  ++   + PP +  + G  G    G +GSP    
Sbjct: 1444 GPMGPPGLP--GLKGDPGSKGEKGHPGLI-GLIGPPGEQGEKGDRGL--PGTQGSPGAKG 1498

Query: 519  QLLKRKRKLGVVPVNGSGLSTPAWPPLQ-QEGP-----PTGPAEGANSHTTLPQRRRLQK 572
                     G +P     L  P  P L   +GP      TGPA G    + LP       
Sbjct: 1499 D--------GGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA-GQKGDSGLP------- 1542

Query: 573  KKAGPGSLELCGLPSQKTASLKKRKKMRVMSNLV--EHNGVLESEAGQPQALGSSGTCSS 630
                PGS    G   Q    L  +K  R    +     + +L+   G  +  GS  +   
Sbjct: 1543 --GPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNS--- 1597

Query: 631  LKKQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGP 670
                 L+ + + +KF       P   R  K    +HP  P
Sbjct: 1598 -----LKQDIEHMKFPMGTQTNPA--RTCKDLQLSHPDFP 1630



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 53/183 (28%), Positives = 69/183 (37%), Gaps = 61/183 (33%)

Query: 410  QPENPGPGGAA--PSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVP 467
            QP  PGP G A  P     RG  P A+G +    R  E GA+       E+G+E PP   
Sbjct: 1355 QPGPPGPSGEAGPPGPPGKRG-PPGAAGAEG---RQGEKGAKG------EAGAEGPP--- 1401

Query: 468  MHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKL 527
                                           ++GP G  PQGP G P  G + L+     
Sbjct: 1402 ------------------------------GKTGPVG--PQGPAGKP--GPEGLR----- 1422

Query: 528  GVV-PVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLP 586
            G+  PV   GL   A     Q+GPP GP  G      L      + +K  PG + L G P
Sbjct: 1423 GIPGPVGEQGLPGAA----GQDGPP-GPM-GPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1476

Query: 587  SQK 589
             ++
Sbjct: 1477 GEQ 1479


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 66/280 (23%), Positives = 96/280 (34%), Gaps = 42/280 (15%)

Query: 399  RRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEES 458
            R+ +K  K     E P PG   P   Q    +P   GL+ +   V E G    +      
Sbjct: 1334 RQGEKGAKGEAGAEGP-PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392

Query: 459  GSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGA 518
            G   PP +P    +  P  K  + H  ++   + PP +  + G  G    G +GSP    
Sbjct: 1393 GPMGPPGLP--GLKGDPGSKGEKGHPGLI-GLIGPPGEQGEKGDRGL--PGTQGSPGAKG 1447

Query: 519  QLLKRKRKLGVVPVNGSGLSTPAWPPLQ-QEGP-----PTGPAEGANSHTTLPQRRRLQK 572
                     G +P     L  P  P L   +GP      TGPA G    + LP       
Sbjct: 1448 D--------GGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA-GQKGDSGLP------- 1491

Query: 573  KKAGPGSLELCGLPSQKTASLKKRKKMRVMSNLV--EHNGVLESEAGQPQALGSSGTCSS 630
                PGS    G   Q    L  +K  R    +     + +L+   G  +  GS  +   
Sbjct: 1492 --GPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNS--- 1546

Query: 631  LKKQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGP 670
                 L+ + + +KF       P   R  K    +HP  P
Sbjct: 1547 -----LKQDIEHMKFPMGTQTNPA--RTCKDLQLSHPDFP 1579



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 53/183 (28%), Positives = 69/183 (37%), Gaps = 61/183 (33%)

Query: 410  QPENPGPGGAA--PSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVP 467
            QP  PGP G A  P     RG  P A+G +    R  E GA+       E+G+E PP   
Sbjct: 1304 QPGPPGPSGEAGPPGPPGKRG-PPGAAGAEG---RQGEKGAKG------EAGAEGPP--- 1350

Query: 468  MHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKL 527
                                           ++GP G  PQGP G P  G + L+     
Sbjct: 1351 ------------------------------GKTGPVG--PQGPAGKP--GPEGLR----- 1371

Query: 528  GVV-PVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLP 586
            G+  PV   GL   A     Q+GPP GP  G      L      + +K  PG + L G P
Sbjct: 1372 GIPGPVGEQGLPGAA----GQDGPP-GPM-GPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1425

Query: 587  SQK 589
             ++
Sbjct: 1426 GEQ 1428


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 66/280 (23%), Positives = 96/280 (34%), Gaps = 42/280 (15%)

Query: 399  RRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEES 458
            R+ +K  K     E P PG   P   Q    +P   GL+ +   V E G    +      
Sbjct: 1373 RQGEKGAKGEAGAEGP-PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431

Query: 459  GSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGA 518
            G   PP +P    +  P  K  + H  ++   + PP +  + G  G    G +GSP    
Sbjct: 1432 GPMGPPGLP--GLKGDPGSKGEKGHPGLI-GLIGPPGEQGEKGDRGL--PGTQGSPGAKG 1486

Query: 519  QLLKRKRKLGVVPVNGSGLSTPAWPPLQ-QEGP-----PTGPAEGANSHTTLPQRRRLQK 572
                     G +P     L  P  P L   +GP      TGPA G    + LP       
Sbjct: 1487 D--------GGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA-GQKGDSGLP------- 1530

Query: 573  KKAGPGSLELCGLPSQKTASLKKRKKMRVMSNLV--EHNGVLESEAGQPQALGSSGTCSS 630
                PGS    G   Q    L  +K  R    +     + +L+   G  +  GS  +   
Sbjct: 1531 --GPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNS--- 1585

Query: 631  LKKQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGP 670
                 L+ + + +KF       P   R  K    +HP  P
Sbjct: 1586 -----LKQDIEHMKFPMGTQTNPA--RTCKDLQLSHPDFP 1618



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 53/183 (28%), Positives = 69/183 (37%), Gaps = 61/183 (33%)

Query: 410  QPENPGPGGAA--PSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVP 467
            QP  PGP G A  P     RG  P A+G +    R  E GA+       E+G+E PP   
Sbjct: 1343 QPGPPGPSGEAGPPGPPGKRG-PPGAAGAEG---RQGEKGAKG------EAGAEGPP--- 1389

Query: 468  MHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKL 527
                                           ++GP G  PQGP G P  G + L+     
Sbjct: 1390 ------------------------------GKTGPVG--PQGPAGKP--GPEGLR----- 1410

Query: 528  GVV-PVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLP 586
            G+  PV   GL   A     Q+GPP GP  G      L      + +K  PG + L G P
Sbjct: 1411 GIPGPVGEQGLPGAA----GQDGPP-GPM-GPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1464

Query: 587  SQK 589
             ++
Sbjct: 1465 GEQ 1467


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/165 (23%), Positives = 67/165 (40%), Gaps = 21/165 (12%)

Query: 362 KHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHL----------QP 411
           +HKKK        +  K K        + +S    +KR+++K+KK+            +P
Sbjct: 674 RHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKP 733

Query: 412 ENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAE----ATSSTGEESGSEHPPAVP 467
           E PG G  AP   + R R  + S  ++L A     G +      SS+ +  G +H   +P
Sbjct: 734 EPPGSGSPAP--PRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELP 791

Query: 468 MHNKRKR--PRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGP 510
             + ++R   ++ S  +HR    S     ED   +     H + P
Sbjct: 792 PSSCQRRAGTKRSSRSSHRSQPSSG---DEDSDDASSHRLHQKSP 833


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
            subunit [Homo sapiens]
          Length = 2339

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 73/315 (23%), Positives = 121/315 (38%), Gaps = 35/315 (11%)

Query: 332  QDLSEGSSISQLSFAE-DISADEDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEE 390
            Q   E + +S +S A   I+A + +   ++   +++ ++L     L+  + S      E 
Sbjct: 736  QKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQL----RLQNLRASCEALYSEM 791

Query: 391  DSESSLQ----KRRRKKKKKHHLQP---ENPGPGGAAPSLEQNRGREPEA-SGLKALKAR 442
            D E  L+    +  R   K H  +P   E    G   P   + R    EA  G+   +  
Sbjct: 792  DPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAEAPEGVDPPRRH 851

Query: 443  VAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQ--- 499
                  + T + G++  +E P A    +     R++ PR HR   + A  PPE  S+   
Sbjct: 852  HRHRDKDKTPAAGDQDRAEAPKA---ESGEPGAREERPRPHRSHSKEAAGPPEARSERGR 908

Query: 500  -SGPSGSHPQGPRGSPTGGAQLLKRKRKL--GVVPVNGSGLSTPAWPPLQQEGPPTGPAE 556
              GP G      RGSP   A+   R+ +      P      +        + GP  GP E
Sbjct: 909  GPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRGGPRAGPRE 968

Query: 557  GANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEA 616
              +     P RR   + KA P    +    ++K A+ K+       + +VE +   E   
Sbjct: 969  AESGEE--PARRHRARHKAQPAHEAVEKETTEKEATEKE-------AEIVEADKEKELRN 1019

Query: 617  GQPQA----LGSSGT 627
             QP+     L +SGT
Sbjct: 1020 HQPREPHCDLETSGT 1034


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 6/169 (3%)

Query: 347 EDISADEDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKK 406
           +++  +++ Q   + + K++  K LE+   +KEK   +  ++E++ E  L+K R K ++K
Sbjct: 543 KELEKEQEKQREMEKERKQEKEKELER---QKEKEKELQKMKEQEKECELEKEREKLEEK 599

Query: 407 HHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAV 466
              +  N  P       E +  +E E    +    R  +        T  ESGS+  PAV
Sbjct: 600 IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAV 659

Query: 467 PMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPT 515
                ++  +   PR  R+  +   +  +   Q    G  PQ     P+
Sbjct: 660 LSGYFKQFQKSLPPRFQRQQEQ---MKQQQWQQQQQQGVLPQTVPSQPS 705



 Score = 30.0 bits (66), Expect = 8.3
 Identities = 51/247 (20%), Positives = 90/247 (36%), Gaps = 38/247 (15%)

Query: 342 QLSFAEDISADEDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQK--- 398
           +L   E   + E+ +   + K +++  +L ++   E+EK        +++ E  L+K   
Sbjct: 491 KLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550

Query: 399 ------RRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLK-ALKARVAEPGAEAT 451
                 + RK++K+  L+ +           EQ +  E E    K   K    EP  E  
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPM 610

Query: 452 SSTGEESGS---EHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGP---SGS 505
               E   S   E  P     +  +  ++ +P  H          PE  SQ  P   SG 
Sbjct: 611 VEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHE-------TEPESGSQPRPAVLSGY 663

Query: 506 HPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQEG--PPTGPAEGANSHTT 563
             Q  +  P       +R+++          +    W   QQ+G  P T P++ ++S   
Sbjct: 664 FKQFQKSLP----PRFQRQQE---------QMKQQQWQQQQQQGVLPQTVPSQPSSSTVP 710

Query: 564 LPQRRRL 570
            P  R L
Sbjct: 711 PPPHRPL 717


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 48/170 (28%), Positives = 58/170 (34%), Gaps = 28/170 (16%)

Query: 414 PGPGGAAPSLEQNRGREPEASGLKALKARVAEPGA-EATSSTGEESGSEHPPAVPMHNKR 472
           PG G A P+        P  SG        A PG+    + T   + +  PP  P     
Sbjct: 119 PGVGSAPPASSSAPPATPPTSG--------APPGSGPGPTPTPPPAVTSAPPGAPP---- 166

Query: 473 KRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPR-GSPTGGAQLLKRKRKLGVVP 531
             P   S        ++   PP   +  GP     QGP  G P GG      K   G  P
Sbjct: 167 --PTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGG------KMPGGPKP 218

Query: 532 VNGSGLSTPAW---PPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPG 578
             G GLSTP     PP +  G P G   G   H    Q+        GPG
Sbjct: 219 GGGPGLSTPGGHPKPPHRGGGEPRG---GRQHHPPYHQQHHQGPPPGGPG 265


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 67/354 (18%), Positives = 129/354 (36%), Gaps = 47/354 (13%)

Query: 309 EMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQGKHKK--K 366
           E +S +    +  K   K + K Q   + +S+S+    E+    E + +    K  +  K
Sbjct: 157 EESSEEEEKGYKGKTRKKPVVKKQAPGK-ASVSRKQAREESEESEAEPVQRTAKKVEGNK 215

Query: 367 GNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQN 426
           G K L+++  E+E    +   ++E  E  +++  +++ ++           G   S  + 
Sbjct: 216 GTKSLKES--EQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREE 273

Query: 427 RGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREM 486
           R  + ++   + L    +E   +  +S+G++SG +  P V   ++ +   K   R     
Sbjct: 274 RSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRL---- 329

Query: 487 LESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQ 546
                        SG S       +G PT  A+  ++  +LG      S L        +
Sbjct: 330 -------------SGSSEDEEDSGKGEPT--AKGSRKMARLGSTSGEESDLEREV-SDSE 373

Query: 547 QEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCG-----------------LPSQK 589
             G P G  +  +S  +  + R      +  GS E  G                 L    
Sbjct: 374 AGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSGRRGEDHPAVMRLKRYI 433

Query: 590 TASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGT-----CSSLKKQKLRA 638
            A    R   +++ +   H   L     + +ALG  GT     C +LK+Q+  A
Sbjct: 434 RACGAHRNYKKLLGSCCSHKERLSILRAELEALGMKGTPSLGKCRALKEQREEA 487


>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
          Length = 1059

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 19/211 (9%)

Query: 378 KEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLK 437
           +   S V  +++ +++++ + R+          P   GP  + PSL       P A+   
Sbjct: 542 RRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPR-SPPSLRCGEASPPSAACGS 600

Query: 438 ALKARVAEPGAE-ATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPED 496
                VA P  E      GEE   E P A    +   RPR  SP +HR   E +    E 
Sbjct: 601 PASQLVATPSLELGPIPAGEEKALELPLAA---SSIPRPRTPSPESHRSPAEGS----ER 653

Query: 497 MSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPL----QQEGPPT 552
           +S S P      GP  SPT     +        V   GS  ST     L    +Q  PP+
Sbjct: 654 LSLS-PLRGGEAGPDASPTVTTPTVTTPSLPAEV---GSPHSTEVDESLSVSFEQVLPPS 709

Query: 553 GPAEGANSHTTLPQRRRLQKKKAGPGSLELC 583
            P   A    +LP R    ++ A P  ++LC
Sbjct: 710 APTSEAG--LSLPLRGPRARRSASPHDVDLC 738


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 64/267 (23%), Positives = 91/267 (34%), Gaps = 29/267 (10%)

Query: 431  PEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKK---------SPR 481
            P A  + + K   A P  +   +T     +  PPAV     +  P  K         SP 
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609

Query: 482  AHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKR--------KLGV-VPV 532
                    AV PP    + GP+   P+G   SP      LK           K+G  VP 
Sbjct: 1610 PKEAPTPPAVTPPSP--EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667

Query: 533  NGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTAS 592
               GL     P   +E     PA  +    T P R+  Q KK+   S  +C  PS K  S
Sbjct: 1668 ASKGLPAKKGPTALKE-VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS 1726

Query: 593  LKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPK 652
                  +     L       ++  G+  +    G  +   + K         F+   LPK
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP-PESKASTPLTAAAFE-KVLPK 1784

Query: 653  PLFFRRAKSSTATHPPGPAVQLNKTPS 679
            P      +S++ +  P P V L   PS
Sbjct: 1785 P------ESASVSAAPSPPVSLPLAPS 1805



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 79/348 (22%), Positives = 113/348 (32%), Gaps = 72/348 (20%)

Query: 414  PGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRK 473
            P    A P   +     P   G     A    P  +   +T    G+   PA    + + 
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 474  RPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVN 533
                 SP+        A  PP    + GP+   P+G    P      LK    L   P  
Sbjct: 1231 GLATPSPKG--APTTPAATPPSP--KGGPATPPPKGAPTPPAATPPSLKGG--LATPPHK 1284

Query: 534  GSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASL 593
            G+       PP  + GP T P +GA +    P        K  PG+    G P+    + 
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPT----PPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340

Query: 594  KKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKP 653
               K            G     A  P + G   T SS +                  P P
Sbjct: 1341 PSPK------------GTPTLPATTPSSKGGPTTPSSKEG-----------------PTP 1371

Query: 654  LFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRV 713
                   ++T +H  GPA+    TP S K       R       K D      PT P+ +
Sbjct: 1372 ------PAATPSHKGGPAM----TPPSPK-------RGPAIPSPKGD------PTSPAVI 1408

Query: 714  AFDPEQKPLHGVLK----TPT----SSPASSPLVAKK-PLTTTPRRRP 752
               P++ P   V +    TP+    + PA +P+  KK P T+ P+  P
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456



 Score = 37.0 bits (84), Expect = 0.068
 Identities = 76/338 (22%), Positives = 110/338 (32%), Gaps = 17/338 (5%)

Query: 414  PGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRK 473
            P P  A P   +     P   G     A    P  +   +T    G+  PPAV   + + 
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPA-ATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021

Query: 474  RPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVP-V 532
             P   +P         A  PP   S  G   + P  P+G+PT  A  L   +     P +
Sbjct: 1022 SPAA-TPFPKGASTPPAATPP---SPKGSPAATPL-PKGAPTTPAATLPSPKGGPATPSL 1076

Query: 533  NGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTAS 592
             G+     A PP  + GP T   +GA     +P        K G  +    G P+   A+
Sbjct: 1077 KGAPTPPAATPPSPKGGPATPSPKGA----PMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132

Query: 593  LKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPK 652
                K    ++            A  P   G   T          A +          P 
Sbjct: 1133 PPSPK--GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190

Query: 653  PLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSR 712
            P   + A ++ A  PP P   L  TPS     T       + +      S   +PT P+ 
Sbjct: 1191 P---KGAPTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 713  VAFDPEQKPLHGVLKTPTSSPASSPLVAKKPLTTTPRR 750
                P+  P     K   + PA++P   K  L T P +
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284



 Score = 33.1 bits (74), Expect = 0.98
 Identities = 70/342 (20%), Positives = 114/342 (33%), Gaps = 51/342 (14%)

Query: 414  PGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRK 473
            P P G   +        P A+   +LK  +A P            G+ +P  V   + + 
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATP---------PHKGAPNPAVVTPPSPKG 1299

Query: 474  RPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVN 533
             P    P+        A  PP   S  G  G+ P  P+G+PT  A      +    +P  
Sbjct: 1300 GPATSPPKG--APTPPAATPP---SPKGSPGTPP--PKGAPTPPAVTPPSPKGTPTLPAT 1352

Query: 534  GSGLSTPAWPPLQQEGPP---TGPAEGANSHTTLPQRRR---LQKKKAGPGSLELCGLPS 587
                      P  +EGP      P+       T P  +R   +   K  P S  +  L  
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412

Query: 588  QKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDT 647
            +K  +    ++     +     G L   A  P +L  +   S+ K       S       
Sbjct: 1413 KKAPATPVTREGAATPS----KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK----GD 1464

Query: 648  PFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSP 707
            P LP            A  PP P     K P + K+V      + + +      + + +P
Sbjct: 1465 PTLP------------AVTPPSP-----KEPPAPKQVA----TSSSPKKAPATPAPMGAP 1503

Query: 708  TGPSRVAFDPEQKPLHGVLKTPTSSPASSPLVAKKPLTTTPR 749
            T P+ +   P++ P     +    +P ++ L  K P T  P+
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545



 Score = 33.1 bits (74), Expect = 0.98
 Identities = 77/353 (21%), Positives = 129/353 (36%), Gaps = 44/353 (12%)

Query: 411  PENPGPGGAA--PSLEQNRGREPEA--SGLKALKARVAEPGAEATSSTGEESGSEHPPAV 466
            P  P P GA   P++  +  +E  A  S  +   A  A   ++ T +T     +  PPA+
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553

Query: 467  PMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRK 526
             + + +K P   +P+        A   P     S P    P   +G+P+    L+     
Sbjct: 1554 TVPSPKKTPAIPTPK-------EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP--- 1603

Query: 527  LGVVPVNGSGLSTP--AWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCG 584
              V   +     TP    PP  ++GP T   +G  +   +     L+     P S+  C 
Sbjct: 1604 -AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS-LKDSPTSPASVT-CK 1660

Query: 585  LPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVK 644
            + +    + K     +  + L E   VL + A +   + ++ T    + +K  A S    
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKE---VLVAPAPESTPIITAPTRKGPQTKKSSATSP--- 1714

Query: 645  FDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSIL 704
               P  P P     +K   +T  P P + + K  S + K           +   + K  L
Sbjct: 1715 ---PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAK---------GKDASHSPKGPL 1762

Query: 705  VSP-----TGPSRVAFDPE-QKPLHGVLKTPTSSPASSPLVAKKPLTTTPRRR 751
              P     T  +  AF+    KP    +    S P S PL A  P+ T P ++
Sbjct: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL-APSPVPTLPPKQ 1814



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 76/360 (21%), Positives = 121/360 (33%), Gaps = 48/360 (13%)

Query: 414  PGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEES-GSEHPPAVPMHNKR 472
            P P  A P   +     P   G     A V  P  + T +    +  S+  P  P   + 
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPA-VTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368

Query: 473  KRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPV 532
              P   +P +H+     A+ PP     S   G     P+G PT  A +    +K    PV
Sbjct: 1369 PTPPAATP-SHKG--GPAMTPP-----SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420

Query: 533  NGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTAS 592
               G +TP+      +G  T PA    +  +L +       K GP +    G P+    +
Sbjct: 1421 TREGAATPS------KGDLTPPAV---TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471

Query: 593  LKKRKKMRVMSNLVEHNGVLESEAGQ--------PQALGSS----GTCSSLKKQKLRAES 640
                K+      +   +   ++ A          P  + SS        S ++  +   +
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531

Query: 641  DFVKFDTP--------FLPKPLFFRRAKSSTATHPP--GPAVQLNKTPSSSKKVTFGLNR 690
              +   TP         +P  +     K + A   P   PA   +K  SS   VT    +
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591

Query: 691  NMTAEFK------KTDKSILVSPTGPSRVAFDPEQKPLHGVLK-TPTSSPASSPLVAKKP 743
               +  +       T  S   +PT P+     PE+ P     K TPTS P +   +   P
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651


>gi|98991767 mitogen-activated protein kinase kinase kinase 7
           interacting protein 3 [Homo sapiens]
          Length = 712

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 55/256 (21%), Positives = 94/256 (36%), Gaps = 31/256 (12%)

Query: 460 SEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQ 519
           S+ P  V  H +  +P + SP+  +         P+    S P    P     SP    Q
Sbjct: 262 SQRPLPVYPHQQNYQPSQYSPKQQQI--------PQSAYHSPPPSQCP-----SPFSSPQ 308

Query: 520 LLKRKRKLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGS 579
              +  +LG + +  S  +TP  P   Q+GPP+   +G++S   LP        K     
Sbjct: 309 HQVQPSQLGHIFMPPSPSTTPPHP--YQQGPPSYQKQGSHSVAYLPYTAS-SLSKGSMKK 365

Query: 580 LELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAE 639
           +E+   PSQ+  +   R    + +     N      A  P +   S   SS  K      
Sbjct: 366 IEITVEPSQRPGTAINRSPSPISNQPSPWNQHSLYTATTPPSSSPSRGISSQPKP----- 420

Query: 640 SDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFG--LNRNMTAEFK 697
                   PF   P++    + +  +  P P+ ++   P++  K+T G     N+     
Sbjct: 421 --------PFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVD 472

Query: 698 KTDKSILVSPTGPSRV 713
           + ++S    P  P  V
Sbjct: 473 QEERSAAPEPIQPISV 488


>gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo
           sapiens]
          Length = 674

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 38/159 (23%), Positives = 58/159 (36%), Gaps = 28/159 (17%)

Query: 360 QGKHKKKGNKLLEKTNLEKEKGSRVF-----------CVEEEDSESSLQKRRRKKKKKHH 408
           QG  K  G +  E+  + +E+G   F            VEEED E +++K   +      
Sbjct: 152 QGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSAL 211

Query: 409 LQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPM 468
                P    + P  E+N+  E         K      GA  TS +   SGS+  P    
Sbjct: 212 SPGSKPSTWVSCPGEEENQATED--------KRTERSKGARKTSVSPRSSGSD--PRSWE 261

Query: 469 HNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHP 507
           +   +   +K  +AH+E  +    P       GP  S P
Sbjct: 262 YRSGEASEEKEEKAHKETGKGEAAP-------GPQSSAP 293


>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
          Length = 1062

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 80/343 (23%), Positives = 116/343 (33%), Gaps = 57/343 (16%)

Query: 407 HHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSS-TGEESGSEHPPA 465
           HHL   +PGPG  A  +     R        + KA+    GA+  SS +   SG    P 
Sbjct: 385 HHLDNSSPGPGSEARGINGGPSR-------MSPKAQRPLRGAKTLSSPSNRPSGETSVPP 437

Query: 466 VPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKR 525
            P   +   PR     A   +  S   PP   +    S S P     S  G   +     
Sbjct: 438 PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASP 497

Query: 526 KLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKK------------ 573
           K+ + P +   LST      ++ G    P E A     +P  +  QK+            
Sbjct: 498 KISLAPTDVKELST------KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQ 551

Query: 574 -KAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLK 632
            K  P S     L       LK+  K +      E +G+L SE          G+  S K
Sbjct: 552 FKLQPSSSPENSLDPFPPRILKEEPKGKEK----EVDGLLTSE--------PMGSPVSSK 599

Query: 633 KQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNM 692
            + +  + D          KP       +     PP P       PS +     GL +  
Sbjct: 600 TESVSDKED----------KPPLAPSGGTEGPEQPPPPC------PSQTGSPPVGLIKGE 643

Query: 693 TAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPAS 735
             +     + +  S   P+   F+P  KPL  V K+ TS+P S
Sbjct: 644 DKDEGPVAEQVKKSTLNPNAKEFNP-TKPLLSVNKS-TSTPTS 684


>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
          Length = 1044

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 80/343 (23%), Positives = 116/343 (33%), Gaps = 57/343 (16%)

Query: 407 HHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSS-TGEESGSEHPPA 465
           HHL   +PGPG  A  +     R        + KA+    GA+  SS +   SG    P 
Sbjct: 385 HHLDNSSPGPGSEARGINGGPSR-------MSPKAQRPLRGAKTLSSPSNRPSGETSVPP 437

Query: 466 VPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKR 525
            P   +   PR     A   +  S   PP   +    S S P     S  G   +     
Sbjct: 438 PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASP 497

Query: 526 KLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKK------------ 573
           K+ + P +   LST      ++ G    P E A     +P  +  QK+            
Sbjct: 498 KISLAPTDVKELST------KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQ 551

Query: 574 -KAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLK 632
            K  P S     L       LK+  K +      E +G+L SE          G+  S K
Sbjct: 552 FKLQPSSSPENSLDPFPPRILKEEPKGKEK----EVDGLLTSE--------PMGSPVSSK 599

Query: 633 KQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNM 692
            + +  + D          KP       +     PP P       PS +     GL +  
Sbjct: 600 TESVSDKED----------KPPLAPSGGTEGPEQPPPPC------PSQTGSPPVGLIKGE 643

Query: 693 TAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPAS 735
             +     + +  S   P+   F+P  KPL  V K+ TS+P S
Sbjct: 644 DKDEGPVAEQVKKSTLNPNAKEFNP-TKPLLSVNKS-TSTPTS 684


>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
          Length = 1097

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 80/343 (23%), Positives = 116/343 (33%), Gaps = 57/343 (16%)

Query: 407 HHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSS-TGEESGSEHPPA 465
           HHL   +PGPG  A  +     R        + KA+    GA+  SS +   SG    P 
Sbjct: 385 HHLDNSSPGPGSEARGINGGPSR-------MSPKAQRPLRGAKTLSSPSNRPSGETSVPP 437

Query: 466 VPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKR 525
            P   +   PR     A   +  S   PP   +    S S P     S  G   +     
Sbjct: 438 PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASP 497

Query: 526 KLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKK------------ 573
           K+ + P +   LST      ++ G    P E A     +P  +  QK+            
Sbjct: 498 KISLAPTDVKELST------KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQ 551

Query: 574 -KAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLK 632
            K  P S     L       LK+  K +      E +G+L SE          G+  S K
Sbjct: 552 FKLQPSSSPENSLDPFPPRILKEEPKGKEK----EVDGLLTSE--------PMGSPVSSK 599

Query: 633 KQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNM 692
            + +  + D          KP       +     PP P       PS +     GL +  
Sbjct: 600 TESVSDKED----------KPPLAPSGGTEGPEQPPPPC------PSQTGSPPVGLIKGE 643

Query: 693 TAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPAS 735
             +     + +  S   P+   F+P  KPL  V K+ TS+P S
Sbjct: 644 DKDEGPVAEQVKKSTLNPNAKEFNP-TKPLLSVNKS-TSTPTS 684


>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
          Length = 1075

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 80/343 (23%), Positives = 116/343 (33%), Gaps = 57/343 (16%)

Query: 407 HHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSS-TGEESGSEHPPA 465
           HHL   +PGPG  A  +     R        + KA+    GA+  SS +   SG    P 
Sbjct: 385 HHLDNSSPGPGSEARGINGGPSR-------MSPKAQRPLRGAKTLSSPSNRPSGETSVPP 437

Query: 466 VPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKR 525
            P   +   PR     A   +  S   PP   +    S S P     S  G   +     
Sbjct: 438 PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASP 497

Query: 526 KLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKK------------ 573
           K+ + P +   LST      ++ G    P E A     +P  +  QK+            
Sbjct: 498 KISLAPTDVKELST------KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQ 551

Query: 574 -KAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLK 632
            K  P S     L       LK+  K +      E +G+L SE          G+  S K
Sbjct: 552 FKLQPSSSPENSLDPFPPRILKEEPKGKEK----EVDGLLTSE--------PMGSPVSSK 599

Query: 633 KQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNM 692
            + +  + D          KP       +     PP P       PS +     GL +  
Sbjct: 600 TESVSDKED----------KPPLAPSGGTEGPEQPPPPC------PSQTGSPPVGLIKGE 643

Query: 693 TAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPAS 735
             +     + +  S   P+   F+P  KPL  V K+ TS+P S
Sbjct: 644 DKDEGPVAEQVKKSTLNPNAKEFNP-TKPLLSVNKS-TSTPTS 684


>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
          Length = 1044

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 80/343 (23%), Positives = 116/343 (33%), Gaps = 57/343 (16%)

Query: 407 HHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSS-TGEESGSEHPPA 465
           HHL   +PGPG  A  +     R        + KA+    GA+  SS +   SG    P 
Sbjct: 385 HHLDNSSPGPGSEARGINGGPSR-------MSPKAQRPLRGAKTLSSPSNRPSGETSVPP 437

Query: 466 VPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKR 525
            P   +   PR     A   +  S   PP   +    S S P     S  G   +     
Sbjct: 438 PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASP 497

Query: 526 KLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKK------------ 573
           K+ + P +   LST      ++ G    P E A     +P  +  QK+            
Sbjct: 498 KISLAPTDVKELST------KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQ 551

Query: 574 -KAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLK 632
            K  P S     L       LK+  K +      E +G+L SE          G+  S K
Sbjct: 552 FKLQPSSSPENSLDPFPPRILKEEPKGKEK----EVDGLLTSE--------PMGSPVSSK 599

Query: 633 KQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNM 692
            + +  + D          KP       +     PP P       PS +     GL +  
Sbjct: 600 TESVSDKED----------KPPLAPSGGTEGPEQPPPPC------PSQTGSPPVGLIKGE 643

Query: 693 TAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPAS 735
             +     + +  S   P+   F+P  KPL  V K+ TS+P S
Sbjct: 644 DKDEGPVAEQVKKSTLNPNAKEFNP-TKPLLSVNKS-TSTPTS 684


>gi|221316599 chromogranin B precursor [Homo sapiens]
          Length = 677

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 47/199 (23%), Positives = 81/199 (40%), Gaps = 26/199 (13%)

Query: 242 GDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDYK 301
           G  S E   E + SL  + S+    +   HS K    DE         E+ G   Q   +
Sbjct: 127 GGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKSQREDEE--------EEEGENYQKGER 178

Query: 302 ---AVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSE------GSSISQLSFAEDISAD 352
              +  ++ LE          N ++ +  IKK + ++       G S  +    E  S +
Sbjct: 179 GEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQE 238

Query: 353 EDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKH-HLQP 411
             ++  SQ  H ++ +K   ++  E E+G       EED+ S + KRR + +  H   +P
Sbjct: 239 SGEETGSQENHPQE-SKGQPRSQEESEEG-------EEDATSEVDKRRTRPRHHHGRSRP 290

Query: 412 ENPGPGGAAPSLEQNRGRE 430
           +    GG+ PS E+   +E
Sbjct: 291 DRSSQGGSLPSEEKGHPQE 309


>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
          Length = 1374

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 51/209 (24%), Positives = 67/209 (32%), Gaps = 35/209 (16%)

Query: 404 KKKHHLQPENPGPGGAAPSLEQNRGREP----------EASGLKALKARVAEPGAEATSS 453
           K+     PE   PG     L+    +EP           A GL      V     E  SS
Sbjct: 712 KQTPRASPEPGYPGEPLLGLQAASAQEPGCCPGLPHLCSAQGLAPAPCLVTPSWTETASS 771

Query: 454 TGEESGSEHPPAVPMHNKRKR----PRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQG 509
                G +HP A P           PR   P       E A LP E+ S      + P  
Sbjct: 772 -----GGDHPQAEPKLATEAEGTTGPRLPLPSVPSPSQEGAPLPSEEASAPDAPDALPDS 826

Query: 510 PRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTT------ 563
           P  +  G    +K    L     NGS  S     P  ++        G  + T+      
Sbjct: 827 PTPATGGEVSAIKLASAL-----NGSSSSPEVEAPSSEDEDTAEATSGIFTDTSSDGLQA 881

Query: 564 -----LPQRRRLQKKKAGPGSLELCGLPS 587
                +P  R LQK+   P SL+   +PS
Sbjct: 882 RRPDVVPAFRSLQKQVGTPDSLDSLDIPS 910


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 42/175 (24%), Positives = 65/175 (37%), Gaps = 16/175 (9%)

Query: 362 KHKKKGNKLLEKT-NLEKEK------GSRVFCVEEEDSES-SLQKRRRKKKKKHHLQPEN 413
           +H+ + +K   K  N EK++      G R        S S SL       +    L P++
Sbjct: 223 RHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKH 282

Query: 414 PGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRK 473
              G    S   +  R P  SG     +       +    +G+ SG+        H+   
Sbjct: 283 RDEGRKTGSQRSSGSRSPSPSGGSGWGS------PQRNGGSGQRSGAHGGRPGSAHSPPD 336

Query: 474 RPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHP--QGPRGSPTGGAQLLKRKRK 526
           +P   SPR   +   +A  PP    +S    S P  QG  G   GGA   +R+R+
Sbjct: 337 KPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRR 391



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 68/295 (23%), Positives = 101/295 (34%), Gaps = 49/295 (16%)

Query: 362 KHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKK--KKHHLQPENPGPGGA 419
           K KKKG     + + +K +      +E E S  S    R+KKK  KKH     + G    
Sbjct: 171 KKKKKGG---HRRSRKKRR------LESECSCGSSSPLRKKKKSVKKHRRDRSDSG---- 217

Query: 420 APSLEQNRGREPEASGLKALKARVAEPGAEATSSTG-----EESGSEHPPAVPMHNKRKR 474
                + + R    S     K +  E     T S G       SGS H P++  H    R
Sbjct: 218 ----SRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSR 273

Query: 475 -PRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVN 533
            P + SP+   E  ++            PSG       GSP       +R    G  P  
Sbjct: 274 SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGG---SGWGSPQRNGGSGQRSGAHGGRP-- 328

Query: 534 GSGLSTPAWPPLQQ--------EGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGL 585
           GS  S P  P               PT PA G  S    P  R     +   G     G 
Sbjct: 329 GSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKES----PSPRSAPSSQGRGG--RAAGG 382

Query: 586 PSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAES 640
             ++    ++R++ R  ++     G       +P+     G+  SL + +  ++S
Sbjct: 383 AGRRRRRRRRRRRSRSSASAPRRRG-----RRRPRPAPPRGSSRSLSRARSSSDS 432



 Score = 30.4 bits (67), Expect = 6.4
 Identities = 65/325 (20%), Positives = 109/325 (33%), Gaps = 45/325 (13%)

Query: 412 ENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNK 471
           E+P P  +APS +   GR    +G +  + R       + S+             P    
Sbjct: 362 ESPSPR-SAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASA-------------PRRRG 407

Query: 472 RKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVP 531
           R+RPR   PR     L  A    +  S  G  G  P+       GG     ++R     P
Sbjct: 408 RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467

Query: 532 VNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTA 591
            + S       P     G   GP   ++S +  P  R     ++   S          + 
Sbjct: 468 ASTS-------PSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSP 520

Query: 592 SLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLP 651
           S     K  +  +         SEA   +A   S + S ++K++          D+P   
Sbjct: 521 SRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRR---------DSPSFM 571

Query: 652 KPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPS 711
           +P   RR  S+       P      +PSSS          +++++     S   SP G S
Sbjct: 572 EP---RRITSARKR----PIPYYRPSPSSSSSC-------LSSDYSTRSHSRSPSP-GHS 616

Query: 712 RVAFDPEQKPLHGVLKTPTSSPASS 736
             ++           ++P+ +P+ S
Sbjct: 617 HGSYSSRSHGTRSRTRSPSRTPSPS 641


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,888,319
Number of Sequences: 37866
Number of extensions: 1770036
Number of successful extensions: 9596
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 614
Number of HSP's that attempted gapping in prelim test: 8167
Number of HSP's gapped (non-prelim): 1809
length of query: 758
length of database: 18,247,518
effective HSP length: 110
effective length of query: 648
effective length of database: 14,082,258
effective search space: 9125303184
effective search space used: 9125303184
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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