Guide to the Human Genome
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Search of human proteins with 57546899

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57546899 myeloid/lymphoid or mixed-lineage leukemia
translocated to, 10 isoform b [Homo sapiens]
         (1011 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca...  2024   0.0  
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat...  2014   0.0  
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora...   670   0.0  
gi|51173722 bromodomain and PHD finger-containing protein 1 isof...   172   1e-42
gi|51173720 bromodomain and PHD finger-containing protein 1 isof...   172   1e-42
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi...   164   4e-40
gi|11321642 bromodomain containing protein 1 [Homo sapiens]           161   3e-39
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]            143   9e-34
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]            143   9e-34
gi|117190334 PHD finger protein 16 [Homo sapiens]                     139   1e-32
gi|7662006 PHD finger protein 16 [Homo sapiens]                       139   1e-32
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]        134   3e-31
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]         134   3e-31
gi|40556370 PHD finger protein 15 [Homo sapiens]                      134   4e-31
gi|45504380 jumonji domain containing 2B [Homo sapiens]               105   3e-22
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]    104   5e-22
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]    104   5e-22
gi|98986459 jumonji domain containing 2A [Homo sapiens]               100   1e-20
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    75   3e-13
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]     72   3e-12
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]     72   3e-12
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    68   5e-11
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        67   8e-11
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        66   1e-10
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    59   2e-08
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            56   1e-07
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            56   1e-07
gi|91982772 mucin 17 [Homo sapiens]                                    56   1e-07
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            56   2e-07
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            56   2e-07

>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
            to, 10 isoform b [Homo sapiens]
          Length = 1011

 Score = 2024 bits (5244), Expect = 0.0
 Identities = 1011/1011 (100%), Positives = 1011/1011 (100%)

Query: 1    MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQ 60
            MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQ
Sbjct: 1    MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQ 60

Query: 61   VPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM 120
            VPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM
Sbjct: 61   VPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM 120

Query: 121  EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEE 180
            EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEE
Sbjct: 121  EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEE 180

Query: 181  EGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDK 240
            EGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDK
Sbjct: 181  EGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDK 240

Query: 241  HKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAH 300
            HKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAH
Sbjct: 241  HKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAH 300

Query: 301  TSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSV 360
            TSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSV
Sbjct: 301  TSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSV 360

Query: 361  KSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGL 420
            KSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGL
Sbjct: 361  KSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGL 420

Query: 421  PSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR 480
            PSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR
Sbjct: 421  PSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR 480

Query: 481  PKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGS 540
            PKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGS
Sbjct: 481  PKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGS 540

Query: 541  EISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQS 600
            EISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQS
Sbjct: 541  EISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQS 600

Query: 601  SGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSEN 660
            SGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSEN
Sbjct: 601  SGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSEN 660

Query: 661  NQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLL 720
            NQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLL
Sbjct: 661  NQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLL 720

Query: 721  ERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSV 780
            ERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSV
Sbjct: 721  ERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSV 780

Query: 781  PFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQS 840
            PFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQS
Sbjct: 781  PFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQS 840

Query: 841  TSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIG 900
            TSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIG
Sbjct: 841  TSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIG 900

Query: 901  ALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLL 960
            ALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLL
Sbjct: 901  ALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLL 960

Query: 961  SDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFSPSMEIMQVRK 1011
            SDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFSPSMEIMQVRK
Sbjct: 961  SDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFSPSMEIMQVRK 1011


>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
            to, 10 isoform a [Homo sapiens]
          Length = 1027

 Score = 2014 bits (5217), Expect = 0.0
 Identities = 1011/1027 (98%), Positives = 1011/1027 (98%), Gaps = 16/1027 (1%)

Query: 1    MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQ 60
            MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQ
Sbjct: 1    MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQ 60

Query: 61   VPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM 120
            VPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM
Sbjct: 61   VPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM 120

Query: 121  EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEE 180
            EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEE
Sbjct: 121  EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEE 180

Query: 181  EGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDK 240
            EGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDK
Sbjct: 181  EGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDK 240

Query: 241  HKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAH 300
            HKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAH
Sbjct: 241  HKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAH 300

Query: 301  TSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSV 360
            TSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSV
Sbjct: 301  TSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSV 360

Query: 361  KSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGL 420
            KSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGL
Sbjct: 361  KSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGL 420

Query: 421  PSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR 480
            PSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR
Sbjct: 421  PSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR 480

Query: 481  PKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGS 540
            PKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGS
Sbjct: 481  PKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGS 540

Query: 541  EISMQYRHDGACPTTTFSELLNAIHN----------------GIYNSNDVAVSFPNVVSG 584
            EISMQYRHDGACPTTTFSELLNAIHN                GIYNSNDVAVSFPNVVSG
Sbjct: 541  EISMQYRHDGACPTTTFSELLNAIHNDRGDSSTLTKQELKFIGIYNSNDVAVSFPNVVSG 600

Query: 585  SGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYG 644
            SGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYG
Sbjct: 601  SGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYG 660

Query: 645  NRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNS 704
            NRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNS
Sbjct: 661  NRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNS 720

Query: 705  SLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNL 764
            SLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNL
Sbjct: 721  SLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNL 780

Query: 765  TAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPD 824
            TAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPD
Sbjct: 781  TAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPD 840

Query: 825  NSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQP 884
            NSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQP
Sbjct: 841  NSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQP 900

Query: 885  VTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATH 944
            VTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATH
Sbjct: 901  VTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATH 960

Query: 945  PMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFSPSM 1004
            PMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFSPSM
Sbjct: 961  PMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFSPSM 1020

Query: 1005 EIMQVRK 1011
            EIMQVRK
Sbjct: 1021 EIMQVRK 1027


>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 6 [Homo sapiens]
          Length = 1093

 Score =  670 bits (1729), Expect = 0.0
 Identities = 454/1047 (43%), Positives = 603/1047 (57%), Gaps = 159/1047 (15%)

Query: 18  MKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERA 77
           MKEM+GGCCVCSDERGWAENPLVYCDGH CSVAVHQACYGIVQVPTGPWFCRKCESQERA
Sbjct: 1   MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERA 60

Query: 78  ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTC 137
           ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANV TMEPIVLQ VPHDR+NKTC
Sbjct: 61  ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTC 120

Query: 138 YICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYH 197
           YIC+EQGRESKAA+GACMTCN+HGCRQAFHVTCAQ AGLLCEEE    DNV+YCGYCKYH
Sbjct: 121 YICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180

Query: 198 FSKLKKSKRGSNR--------------------SYDQSLSDSSSHSQDK---HHEK-EKK 233
           FSK+K S+  S                      S  +S S S S  Q+K   HHE+ +KK
Sbjct: 181 FSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKK 240

Query: 234 KYKEKDKHKQKHKKQPEPSPA-LVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNA 292
             K+K++ KQKHKK+PE  P+ L P +  T +K  +S S++                   
Sbjct: 241 SRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSS------------------- 281

Query: 293 NFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGS 352
                S H +S ++ SE+   E KGKKSS+HS   +G+K   G+   +  SA+S     S
Sbjct: 282 -----SHHEASTQETSES-SRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASS--SSSS 333

Query: 353 FSGTPGSVKSSSGSSVQSPQDFLSFTDSDL-RNDSYS-------HSQQSSATKDVHKGES 404
            S + G     + SS+QS  DF +F   +    D YS        +  S +  +  K + 
Sbjct: 334 SSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADL 393

Query: 405 GSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAG-----YKR----AQT 455
             Q+   + F  ++   +T++ + + ++   SPGD  +  +  +G     +KR    + T
Sbjct: 394 FEQKVVFSGFGPIMRFSTTTSSSGRARA--PSPGDYKSPHVTGSGASAGTHKRMPALSAT 451

Query: 456 SGIEEET----VKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSI 511
               +ET    +KEKK K +K+S+HGPGRPKG++N+E         A+P+   A  AG  
Sbjct: 452 PVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTG----GPAAPSLPSAQLAGFT 507

Query: 512 TSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTF-SELLNAIHNGIYN 570
            +++   SP     GSL      SS +G   S  +   G+ P+ +  S LL A   GIY 
Sbjct: 508 ATAA---SP--FSGGSLV-----SSGLGGLSSRTFGPSGSLPSLSLESPLLGA---GIYT 554

Query: 571 SNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSP--SAVSSAAPAVATTQAN 628
           SN   +S    +  +  STP+SSS L    +  L ++ + SP  S + S++ +++TTQ  
Sbjct: 555 SNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRL-SRSPFTSTLPSSSASISTTQVF 613

Query: 629 TLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPR 688
           +L+GS+ S   +H++G     ++  L++Q+E++ T+ DL D S     RG+SP+ SLS  
Sbjct: 614 SLAGSTFSLPSTHIFGT-PMGAVNPLLSQAESSHTEPDLEDCSFRC--RGTSPQESLSSM 670

Query: 689 SPVSSLQIRYDQP-----GNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGM 743
           SP+SSL   +DQ      G   L+   P   ++EQLLE+Q  +G+  +       +I+ M
Sbjct: 671 SPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQ-GDGEAGV-------NIVEM 722

Query: 744 LKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITA------NPSPSHQIHT 797
           LK+LH LQ EN+RL+EQI +LTAKKERLQ+LN QLSVPFP + A       P P    + 
Sbjct: 723 LKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGP--YG 780

Query: 798 FSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSAL--STPPP--- 852
              Q A ++DSL++SKSP   +S   DNSL   ++D  S   S SSSS    STPPP   
Sbjct: 781 LPPQ-AGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPL 839

Query: 853 AGQSPAQQGSGVSGV------QQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGN- 905
             QSPA     + G       Q  NG+       G  P  + + A+    G++G L G+ 
Sbjct: 840 LQQSPATLPLALPGAPAPLPPQPQNGL-------GRAPGAAGLGAMPMAEGLLGGLAGSG 892

Query: 906 QLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQQR 965
            L +NG++G LNG        + NP  L+     P  T  +P  L +       L++QQR
Sbjct: 893 GLPLNGLLGGLNG------AAAPNPASLSQAGGAP--TLQLPGCLNS-------LTEQQR 937

Query: 966 QILIHQ----QQFQQLLNSQQLTPVHR 988
            +L  Q    QQ QQLL S QLTP H+
Sbjct: 938 HLLQQQEQQLQQLQQLLASPQLTPEHQ 964


>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
           2 [Homo sapiens]
          Length = 1214

 Score =  172 bits (437), Expect = 1e-42
 Identities = 98/233 (42%), Positives = 132/233 (56%), Gaps = 26/233 (11%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 83
           CC+C+D      N +++CD   C++AVHQ CYG+  +P G W CR+C +S  RA  V C 
Sbjct: 276 CCICNDGECQNSNVILFCDM--CNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331

Query: 84  LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDE 142
           LCP+K GA K+TD+G WAHVVCAL+IPEV FAN   +EPI  ++ +P  R+  TCYIC +
Sbjct: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391

Query: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEE------GNGAD-NVQYCGYCK 195
           +G      +GAC+ C+K  C  AFHVTCAQ AGL  + E       NG   +V+   YC 
Sbjct: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCD 445

Query: 196 YHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQ 248
            H      +  GS R    +LS S     +   E E K +  +   K K K +
Sbjct: 446 IH------TPPGSARRL-PALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSR 491


>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform
           1 [Homo sapiens]
          Length = 1220

 Score =  172 bits (437), Expect = 1e-42
 Identities = 98/233 (42%), Positives = 132/233 (56%), Gaps = 26/233 (11%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 83
           CC+C+D      N +++CD   C++AVHQ CYG+  +P G W CR+C +S  RA  V C 
Sbjct: 276 CCICNDGECQNSNVILFCDM--CNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331

Query: 84  LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDE 142
           LCP+K GA K+TD+G WAHVVCAL+IPEV FAN   +EPI  ++ +P  R+  TCYIC +
Sbjct: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391

Query: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEE------GNGAD-NVQYCGYCK 195
           +G      +GAC+ C+K  C  AFHVTCAQ AGL  + E       NG   +V+   YC 
Sbjct: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCD 445

Query: 196 YHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQ 248
            H      +  GS R    +LS S     +   E E K +  +   K K K +
Sbjct: 446 IH------TPPGSARRL-PALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSR 491


>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
           sapiens]
          Length = 1205

 Score =  164 bits (415), Expect = 4e-40
 Identities = 102/277 (36%), Positives = 144/277 (51%), Gaps = 43/277 (15%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
           CCVC D+     N +++CD   C++AVHQ CYG+  +P G W CR C  Q  +  V C L
Sbjct: 215 CCVCLDDECHNSNVILFCDI--CNLAVHQECYGVPYIPEGQWLCRCC-LQSPSRPVDCIL 271

Query: 85  CPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDEQ 143
           CP+K GA K+T +G WAHVVCA++IPEV FAN   +EPI  + ++P  R+  TCYIC ++
Sbjct: 272 CPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQK 331

Query: 144 GRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEG------NGA-DNVQYCGYCKY 196
           G       GA + C+K  C  AFHVTCAQ AGL  + E       NG    V+   YC+ 
Sbjct: 332 G------LGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCEA 385

Query: 197 HF---SKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKH------------ 241
           H    +   + K  S RS  ++  +      D   E+E++  +E+ +             
Sbjct: 386 HSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVP 445

Query: 242 -------KQKHKKQPE----PSPALVPSLTVTTEKTY 267
                  KQK KK+PE     +P+ +P L V    +Y
Sbjct: 446 KKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIPSY 482


>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
          Length = 1058

 Score =  161 bits (407), Expect = 3e-39
 Identities = 81/181 (44%), Positives = 107/181 (59%), Gaps = 17/181 (9%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
           CC+C D      N +++CD   C++AVHQ CYG+  +P G W CR C  Q RA    C L
Sbjct: 217 CCICMDGECQNSNVILFCDM--CNLAVHQECYGVPYIPEGQWLCRHC-LQSRARPADCVL 273

Query: 85  CPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDEQ 143
           CP+K GA K+TD+  W HVVCAL+IPEV FAN   +EPI  ++++P  R+  TCY+C ++
Sbjct: 274 CPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQK 333

Query: 144 GRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEE-------GNGADNVQYCGYCKY 196
           G       GAC+ C+K  C  AFHVTCAQ AGL  + E       G    +V+   YC  
Sbjct: 334 G------VGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGGTTFSVRKTAYCDV 387

Query: 197 H 197
           H
Sbjct: 388 H 388


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score =  143 bits (360), Expect = 9e-34
 Identities = 86/277 (31%), Positives = 131/277 (47%), Gaps = 24/277 (8%)

Query: 3   SSDRPVSLEDEVSHSMKEM--IGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGI-- 58
           S++  + LE   + S ++M  I  CCVC  +     + ++ CD   C + VH+ CYG+  
Sbjct: 298 SNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDN--CGITVHEGCYGVDG 355

Query: 59  ---------VQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYI 109
                     +  T PWFC  C+         CELCP++DG  K TD G W H+VCALY+
Sbjct: 356 ESDSIMSSASENSTEPWFCDACKC---GVSPSCELCPNQDGIFKETDAGRWVHIVCALYV 412

Query: 110 PEVQFANVSTMEPIVLQSVPHDRYN-KTCYICDEQGRESKAATGACMTCNKHGCRQAFHV 168
           P V F ++  + P+ L  + + +Y  K C  C++      A TG C++C+   CR  FHV
Sbjct: 413 PGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCED---PRFARTGVCISCDAGMCRAYFHV 469

Query: 169 TCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHH 228
           TCAQ  GLL E          +  YCK H  +L +  +  N    QS    S   ++K  
Sbjct: 470 TCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQL 529

Query: 229 EKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEK 265
             E +     +   Q+++ + E + +  P   V  EK
Sbjct: 530 SPEAQ--ARINARLQQYRAKAELARSTRPQAWVPREK 564



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 45/199 (22%), Positives = 69/199 (34%), Gaps = 45/199 (22%)

Query: 226 KHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSIS--------- 276
           K  EKEK+K KEK+K ++K K++   S  +  S   TT  T     N S S         
Sbjct: 115 KEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATE 174

Query: 277 --------GSLKRLEDTTARFTNANFQEVSAHTS-------------SGKDVSETRGSEG 315
                    +L+R        +     ++  + S              G+  S+  GS+G
Sbjct: 175 EQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDG 234

Query: 316 KGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFL 375
             +      SG    +     + G     +SP  +G        V S +           
Sbjct: 235 DNEDDEDEGSGSDEDE----NDEGNDEDHSSPASEGGCKKKKSKVLSRN----------- 279

Query: 376 SFTDSDLRNDSYSHSQQSS 394
           S  D +L NDS + SQ  S
Sbjct: 280 SADDEELTNDSLTLSQSKS 298



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 5/93 (5%)

Query: 200 KLKKSKRGSNRSYDQSLSDSSSHSQDKHHE-----KEKKKYKEKDKHKQKHKKQPEPSPA 254
           +LK S      S ++ L       ++++ E     KEK+K KEK+K K+K +++ +    
Sbjct: 80  QLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKAT 139

Query: 255 LVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTA 287
           +  ++  +   T  +TS  +++ S      TTA
Sbjct: 140 VSENVAASAAATTPATSPPAVNTSPSVPTTTTA 172


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score =  143 bits (360), Expect = 9e-34
 Identities = 86/277 (31%), Positives = 131/277 (47%), Gaps = 24/277 (8%)

Query: 3   SSDRPVSLEDEVSHSMKEM--IGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGI-- 58
           S++  + LE   + S ++M  I  CCVC  +     + ++ CD   C + VH+ CYG+  
Sbjct: 298 SNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDN--CGITVHEGCYGVDG 355

Query: 59  ---------VQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYI 109
                     +  T PWFC  C+         CELCP++DG  K TD G W H+VCALY+
Sbjct: 356 ESDSIMSSASENSTEPWFCDACKC---GVSPSCELCPNQDGIFKETDAGRWVHIVCALYV 412

Query: 110 PEVQFANVSTMEPIVLQSVPHDRYN-KTCYICDEQGRESKAATGACMTCNKHGCRQAFHV 168
           P V F ++  + P+ L  + + +Y  K C  C++      A TG C++C+   CR  FHV
Sbjct: 413 PGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCED---PRFARTGVCISCDAGMCRAYFHV 469

Query: 169 TCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHH 228
           TCAQ  GLL E          +  YCK H  +L +  +  N    QS    S   ++K  
Sbjct: 470 TCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQL 529

Query: 229 EKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEK 265
             E +     +   Q+++ + E + +  P   V  EK
Sbjct: 530 SPEAQ--ARINARLQQYRAKAELARSTRPQAWVPREK 564



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 45/199 (22%), Positives = 69/199 (34%), Gaps = 45/199 (22%)

Query: 226 KHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSIS--------- 276
           K  EKEK+K KEK+K ++K K++   S  +  S   TT  T     N S S         
Sbjct: 115 KEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATE 174

Query: 277 --------GSLKRLEDTTARFTNANFQEVSAHTS-------------SGKDVSETRGSEG 315
                    +L+R        +     ++  + S              G+  S+  GS+G
Sbjct: 175 EQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDG 234

Query: 316 KGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFL 375
             +      SG    +     + G     +SP  +G        V S +           
Sbjct: 235 DNEDDEDEGSGSDEDE----NDEGNDEDHSSPASEGGCKKKKSKVLSRN----------- 279

Query: 376 SFTDSDLRNDSYSHSQQSS 394
           S  D +L NDS + SQ  S
Sbjct: 280 SADDEELTNDSLTLSQSKS 298



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 5/93 (5%)

Query: 200 KLKKSKRGSNRSYDQSLSDSSSHSQDKHHE-----KEKKKYKEKDKHKQKHKKQPEPSPA 254
           +LK S      S ++ L       ++++ E     KEK+K KEK+K K+K +++ +    
Sbjct: 80  QLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKAT 139

Query: 255 LVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTA 287
           +  ++  +   T  +TS  +++ S      TTA
Sbjct: 140 VSENVAASAAATTPATSPPAVNTSPSVPTTTTA 172



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 178 CEEEGNGADNVQYCGYCK--YHFS----KLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKE 231
           C+  G+  +N+  C  C+  YHF      LKKS + +   +     DSSS  +D+ +E E
Sbjct: 874 CKGTGDN-ENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDE-NEAE 931

Query: 232 KKKYKEKDKHKQKHKKQ 248
           +K   ++   +QK+ K+
Sbjct: 932 RKNISQELNMEQKNPKK 948


>gi|117190334 PHD finger protein 16 [Homo sapiens]
          Length = 823

 Score =  139 bits (351), Expect = 1e-32
 Identities = 87/218 (39%), Positives = 114/218 (52%), Gaps = 19/218 (8%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
           C VC        N +V+CD   C+V VHQACYGI++VP G W CR C         +C L
Sbjct: 203 CDVCRSPDSEEGNDMVFCDK--CNVCVHQACYGILKVPEGSWLCRSC---VLGIYPQCVL 257

Query: 85  CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
           CP K GALK T  G  WAHV CAL+IPEV  A    MEPI  +  +P  R+   C +C  
Sbjct: 258 CPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC-- 315

Query: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHF---S 199
                K  TGAC+ C+   C  AFHVTCA   GL  +   +  D V++  YC  H     
Sbjct: 316 -----KLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQ 370

Query: 200 KLKKSKRGSNRSYDQS--LSDSSSHSQDKHHEKEKKKY 235
           KL +++   +R+ +QS   S+ +S    K  E E++ Y
Sbjct: 371 KLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFY 408


>gi|7662006 PHD finger protein 16 [Homo sapiens]
          Length = 823

 Score =  139 bits (351), Expect = 1e-32
 Identities = 87/218 (39%), Positives = 114/218 (52%), Gaps = 19/218 (8%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
           C VC        N +V+CD   C+V VHQACYGI++VP G W CR C         +C L
Sbjct: 203 CDVCRSPDSEEGNDMVFCDK--CNVCVHQACYGILKVPEGSWLCRSC---VLGIYPQCVL 257

Query: 85  CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
           CP K GALK T  G  WAHV CAL+IPEV  A    MEPI  +  +P  R+   C +C  
Sbjct: 258 CPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC-- 315

Query: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHF---S 199
                K  TGAC+ C+   C  AFHVTCA   GL  +   +  D V++  YC  H     
Sbjct: 316 -----KLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKHSQNRQ 370

Query: 200 KLKKSKRGSNRSYDQS--LSDSSSHSQDKHHEKEKKKY 235
           KL +++   +R+ +QS   S+ +S    K  E E++ Y
Sbjct: 371 KLGEAEYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFY 408


>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
          Length = 509

 Score =  134 bits (338), Expect = 3e-31
 Identities = 74/180 (41%), Positives = 97/180 (53%), Gaps = 14/180 (7%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
           C VC    G   N +V+CD   C++ VHQACYGI++VP G W CR C       + +C L
Sbjct: 206 CDVCQSPDGEDGNEMVFCDK--CNICVHQACYGILKVPEGSWLCRTC---ALGVQPKCLL 260

Query: 85  CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
           CP K GA+K T +G  W HV CAL+IPEV   +   MEPI  +  +P  R+   C +C+E
Sbjct: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 320

Query: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLK 202
           +        GA + C+   CR AFHVTCA   GL  +      D V++  YC  H S  K
Sbjct: 321 K-------FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRK 373


>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
          Length = 842

 Score =  134 bits (338), Expect = 3e-31
 Identities = 74/180 (41%), Positives = 97/180 (53%), Gaps = 14/180 (7%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
           C VC    G   N +V+CD   C++ VHQACYGI++VP G W CR C       + +C L
Sbjct: 206 CDVCQSPDGEDGNEMVFCDK--CNICVHQACYGILKVPEGSWLCRTC---ALGVQPKCLL 260

Query: 85  CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
           CP K GA+K T +G  W HV CAL+IPEV   +   MEPI  +  +P  R+   C +C+E
Sbjct: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 320

Query: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLK 202
           +        GA + C+   CR AFHVTCA   GL  +      D V++  YC  H S  K
Sbjct: 321 K-------FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRK 373


>gi|40556370 PHD finger protein 15 [Homo sapiens]
          Length = 790

 Score =  134 bits (337), Expect = 4e-31
 Identities = 73/175 (41%), Positives = 94/175 (53%), Gaps = 14/175 (8%)

Query: 25  CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
           C VC    G   N +V+CD   C+V VHQACYGI++VPTG W CR C       + +C L
Sbjct: 202 CDVCRSPEGEDGNEMVFCDK--CNVCVHQACYGILKVPTGSWLCRTC---ALGVQPKCLL 256

Query: 85  CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
           CP + GALK T +G  W HV CAL+IPEV       MEPI  +  +P  R+  +C +C  
Sbjct: 257 CPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLC-- 314

Query: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYH 197
                K  TG C+ C+   C  AFHVTCA   GL         D V++  +C+ H
Sbjct: 315 -----KECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSFCQEH 364


>gi|45504380 jumonji domain containing 2B [Homo sapiens]
          Length = 1096

 Score =  105 bits (261), Expect = 3e-22
 Identities = 52/146 (35%), Positives = 79/146 (54%), Gaps = 8/146 (5%)

Query: 37  NPLVYCDGHGCSVAVHQACYGI-VQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRT 95
           +PL+ C    C + VH +CYGI  ++    W C +C +    A   C LC  + GAL+ T
Sbjct: 755 SPLIACGK--CCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAE--CCLCNLRGGALQMT 810

Query: 96  DNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACM 155
            +  W HV+CA+ +PE +F NV    P+ + ++P  R+   C  C    +  K  +GAC+
Sbjct: 811 TDRRWIHVICAIAVPEARFLNVIERHPVDISAIPEQRWKLKCVYC---RKRMKKVSGACI 867

Query: 156 TCNKHGCRQAFHVTCAQFAGLLCEEE 181
            C+   C  +FHVTCA  AG+L E +
Sbjct: 868 QCSYEHCSTSFHVTCAHAAGVLMEPD 893


>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
          Length = 1047

 Score =  104 bits (259), Expect = 5e-22
 Identities = 65/188 (34%), Positives = 92/188 (48%), Gaps = 20/188 (10%)

Query: 5   DRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHG---------CSVAVHQAC 55
           D  V+ E +    + EM   C + S+E      P  + +  G         C V VH +C
Sbjct: 673 DEVVTSEGKTKPLIPEM---CFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASC 729

Query: 56  YGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQ 113
           YGI   ++  G W C +C+    A    C LC  + GALK+T N  WAHV+CA+ +PEV+
Sbjct: 730 YGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVR 786

Query: 114 FANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQF 173
           F NV     I +  +P  R    C  C  +    K  +GAC+ C+   C  +FHVTCA  
Sbjct: 787 FTNVPERTQIDVGRIPLQRLKLKCIFCRHR---VKRVSGACIQCSYGRCPASFHVTCAHA 843

Query: 174 AGLLCEEE 181
           AG+L E +
Sbjct: 844 AGVLMEPD 851


>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
          Length = 1056

 Score =  104 bits (259), Expect = 5e-22
 Identities = 65/188 (34%), Positives = 92/188 (48%), Gaps = 20/188 (10%)

Query: 5   DRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHG---------CSVAVHQAC 55
           D  V+ E +    + EM   C + S+E      P  + +  G         C V VH +C
Sbjct: 673 DEVVTSEGKTKPLIPEM---CFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASC 729

Query: 56  YGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQ 113
           YGI   ++  G W C +C+    A    C LC  + GALK+T N  WAHV+CA+ +PEV+
Sbjct: 730 YGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVR 786

Query: 114 FANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQF 173
           F NV     I +  +P  R    C  C  +    K  +GAC+ C+   C  +FHVTCA  
Sbjct: 787 FTNVPERTQIDVGRIPLQRLKLKCIFCRHR---VKRVSGACIQCSYGRCPASFHVTCAHA 843

Query: 174 AGLLCEEE 181
           AG+L E +
Sbjct: 844 AGVLMEPD 851


>gi|98986459 jumonji domain containing 2A [Homo sapiens]
          Length = 1064

 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 6/136 (4%)

Query: 47  CSVAVHQACYGIVQVPTGP-WFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVC 105
           CSV VH +CYG+        W C +C +   A    C LC  + GAL+R ++  W HV C
Sbjct: 741 CSVRVHASCYGVPPAKASEDWMCSRCSAN--ALEEDCCLCSLRGGALQRANDDRWVHVSC 798

Query: 106 ALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQA 165
           A+ I E +F N++   P+ +  +P  R+   C  C    +  K   G C+ C+   C  A
Sbjct: 799 AVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCK---KRRKRTAGCCVQCSHGRCPTA 855

Query: 166 FHVTCAQFAGLLCEEE 181
           FHV+CAQ AG++ + +
Sbjct: 856 FHVSCAQAAGVMMQPD 871


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 107/510 (20%), Positives = 193/510 (37%), Gaps = 16/510 (3%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKE--KDKHKQKHKKQPEPSPALVPSLTVTTEK 265
            S+ + D + SDS+ +  + + + +K    +   D            S +   S + +++ 
Sbjct: 515  SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574

Query: 266  TYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSS 325
              +S S++S S S    +  ++  +N++    S+ +S   D S++  S+    KS + SS
Sbjct: 575  NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634

Query: 326  GQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRND 385
                +      N   +   +      + S +  S  SS  S   S  D  + +DS   +D
Sbjct: 635  DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694

Query: 386  SYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSL 445
            S + S+ S ++       S S +   ++ S      S+ +  S   S  +   D  NSS 
Sbjct: 695  SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754

Query: 446  PTAGYKRAQTSGIEEET-VKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSV 504
             +     + +S   + +   +     N    +       + +  N S  S SS S  SS 
Sbjct: 755  SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814

Query: 505  ASAAGSITSS-SLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNA 563
            +S + S  SS S   S +   + S  S     S  GS+     R D +  + +       
Sbjct: 815  SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS---- 870

Query: 564  IHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVA 623
              +   NS+D + S  +  S S SS    SS+     S         S S+ SS +   +
Sbjct: 871  --SDSSNSSDSSDSSDSNES-SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927

Query: 624  TTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSEN-----NQTDQDLGDNSRNLVGRG 678
             +  N+ S  S + + S    + SNSS ++  + S N     +    D  D+S +     
Sbjct: 928  NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987

Query: 679  SSPRGSLSPRSPVSSLQIRYDQPGNSSLEN 708
            SS     S  S  S+     D   +S   N
Sbjct: 988  SSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017



 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 106/492 (21%), Positives = 178/492 (36%), Gaps = 12/492 (2%)

Query: 204  SKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTT 263
            S   SN S     SDSS  S               D          E S +   S + ++
Sbjct: 659  SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS-----SNSSESSDSSDSSDSDSS 713

Query: 264  EKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAH 323
            + + +S SN+S S S    + + +  +N++    S+ +S+  D S++  S+      S+ 
Sbjct: 714  DSSDSSNSNSSDSDSSNSSDSSDS--SNSSDSSDSSDSSNSSDSSDS--SDSSNSSDSSD 769

Query: 324  SSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLR 383
            SS           +     S +S     S S    +   SS SS  S  D  + +DS   
Sbjct: 770  SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829

Query: 384  NDS--YSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLG 441
            +DS   S+S  SS + D   G         +S ++     S+ +  S   S  +   +  
Sbjct: 830  SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889

Query: 442  NSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPT 501
            NSS  +     + +   +     +     N            N N  + S+ S SS S  
Sbjct: 890  NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949

Query: 502  SSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELL 561
            SS  S+  S +S S   S +   N S  S S  SS            D +  + +     
Sbjct: 950  SS-NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008

Query: 562  NAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPA 621
            ++  +   NS+D + S  +  S   S +  SS       S         S S+ SS +  
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068

Query: 622  VATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSP 681
             + +  ++ S  S   + S    N S+SS ++  + S ++    D  D+S +     SS 
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128

Query: 682  RGSLSPRSPVSS 693
                S  S  S+
Sbjct: 1129 SSDSSDSSDSSN 1140



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 109/505 (21%), Positives = 188/505 (37%), Gaps = 17/505 (3%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTY 267
            S+ S D S S  SS S D    K      E D      K     S     + + +++ + 
Sbjct: 601  SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS-----NSSDSSDNSD 655

Query: 268  TSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQ 327
            +S S+NS + S       ++  ++++    S+ +S   D S +  S      S + SS  
Sbjct: 656  SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715

Query: 328  RGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSY 387
                     +  ++ S+ S     S   +  S  S+S  S  S     S   SD  + S 
Sbjct: 716  SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775

Query: 388  SHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPT 447
            S    +S+  +     S S +   +S S+     S S+ +S   S  +S  D  NSS  +
Sbjct: 776  SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS--DSSNSSDSS 833

Query: 448  AGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVAS- 506
                 + +S   + +        N+           + +  N S  S SS S  SS +S 
Sbjct: 834  DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893

Query: 507  ---AAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNA 563
               ++ S  S S   S +   + S  S     S   S+ S       +  ++  S+  N+
Sbjct: 894  SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953

Query: 564  IHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVA 623
              +   NS+D + S  +  S S  S+  S+S     SS       +   S  S ++ +  
Sbjct: 954  SDSS--NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011

Query: 624  TTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRG 683
            ++ ++  S SS S   S    N S+SS ++  + S ++    D  D+S +     SS   
Sbjct: 1012 SSDSSNSSDSSNSSDSS----NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067

Query: 684  SLSPRSPVSSLQIRYDQPGNSSLEN 708
              S  S  S      +   +S   N
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSN 1092



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 96/501 (19%), Positives = 180/501 (35%), Gaps = 19/501 (3%)

Query: 204  SKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTT 263
            S   SN +   S S +SS S D  +  +     +              + +     + ++
Sbjct: 715  SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774

Query: 264  EKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAH 323
            + + +S S++S   S            N++    S+++S   + S++  S       S++
Sbjct: 775  DSSDSSNSSDSNDSS------------NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822

Query: 324  SSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLR 383
            SS           +  +  S +S    GS S +     SS+ S      D  + +DS   
Sbjct: 823  SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882

Query: 384  NDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNS 443
            +DS   S  S ++   +  +S S +   +S        S+ +  S   S  ++  D  NS
Sbjct: 883  SDSNESSNSSDSSDSSNSSDSDSSDSSNSS-------DSSDSSNSSDSSESSNSSDNSNS 935

Query: 444  SLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSS 503
            S  +     + +S     +        +  S         + +  N S  S SS S  SS
Sbjct: 936  SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995

Query: 504  VASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNA 563
             +S + + + SS     +   N S  S S  SS            D +  + +     ++
Sbjct: 996  DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055

Query: 564  IHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVA 623
              +   +S+D + S  +  S   S +  SS      +S         S S+ SS +   +
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115

Query: 624  TTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRG 683
             +  ++ S  S   + S    + SNSS ++  ++S ++    D  D+S +     SS   
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175

Query: 684  SLSPRSPVSSLQIRYDQPGNS 704
              S  S  S      D   +S
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSS 1196



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 113/518 (21%), Positives = 189/518 (36%), Gaps = 28/518 (5%)

Query: 192 GYCKYHFSKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEP 251
           GY  Y F    KS +G     D + SD S+ + D + E +       D      + +   
Sbjct: 449 GYDSYDFDD--KSMQGD----DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502

Query: 252 SPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETR 311
           + +         +   TS +NNS         D+     N N  + +  + SGK  S++ 
Sbjct: 503 NGSDSKGAE-DDDSDSTSDTNNS---------DSNGNGNNGN--DDNDKSDSGKGKSDSS 550

Query: 312 GSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSP 371
            S+     +S+ SS           +   + S+ S     S S +  S  SS  S     
Sbjct: 551 DSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS 610

Query: 372 QDFLSFTDS-DLRNDSY-SHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVT-- 427
            D    +DS D ++DS  S S  S +       +S S +   NS S+     S S+ +  
Sbjct: 611 SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670

Query: 428 SQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQ 487
           S   S  +S  D  NSS  +     + +S        +     +  S         N + 
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSS-----ESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 488 ENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYR 547
            + S+ S SS S  SS +S +   ++SS     +   N S  S S  SS      +    
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 548 HDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQV 607
           +D +  + +     ++  +   +S+D + S  +  S S  S+  S S     SS      
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845

Query: 608 GALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDL 667
            +   S   S+  + ++  +++   S  S +      + SN S  +  +   +N +D D 
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905

Query: 668 GDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSS 705
            D+S N      S   S S  S  SS         NSS
Sbjct: 906 SDSS-NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942



 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 96/504 (19%), Positives = 185/504 (36%), Gaps = 5/504 (0%)

Query: 204  SKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTT 263
            S   S+ S D S S  SS+S +     +       D     +    +   +     + ++
Sbjct: 679  SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738

Query: 264  EKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAH 323
              + +S S++S + S       ++  ++++    S+ +S   + S++  S      S + 
Sbjct: 739  NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798

Query: 324  SSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLR 383
            +S           +  ++ S +S     S S       +SS SS  S     S +DS  R
Sbjct: 799  NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858

Query: 384  NDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNS 443
            +DS S+S  SS + D       S     N  S       +S  +    S  ++  D  +S
Sbjct: 859  SDS-SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS 917

Query: 444  SLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSS 503
            S  +   + + +S  +     +     +            + N  + S+ S SS S +S 
Sbjct: 918  SNSSDSSESSNSS--DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975

Query: 504  VASAAGSITSS-SLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLN 562
             + ++ S  SS S   S +   + S  S     S   S+ S       +  ++  S+  +
Sbjct: 976  SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035

Query: 563  AIHNG-IYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPA 621
            +  +    +S+D + S  +  S   S +  SS       S         S S+ SS +  
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095

Query: 622  VATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSP 681
             + +  ++ S  S   + S    + SNSS ++  + S ++    +  D+S +     SS 
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155

Query: 682  RGSLSPRSPVSSLQIRYDQPGNSS 705
                S  S  S      D   +S+
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSN 1179



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 94/488 (19%), Positives = 177/488 (36%), Gaps = 4/488 (0%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTY 267
            S+ S D S S  SS+S D     +     +              + +     + +++ + 
Sbjct: 737  SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796

Query: 268  TSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQ 327
            +S S++S S S    + + +  ++++    S+++S   D S +  S      S    S  
Sbjct: 797  SSNSSDS-SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855

Query: 328  RGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSY 387
              R      +  +  S +S     S S       +SS SS  S       +DS   +DS 
Sbjct: 856  SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915

Query: 388  SHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLG--NSSL 445
              S  S +++  +  ++ +     NS  +     S+++  S   S  ++  D    NSS 
Sbjct: 916  DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975

Query: 446  PTAGYKRAQTSGIEEET-VKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSV 504
             +     + +S   + +   +     N            + N  + S+ S SS S  SS 
Sbjct: 976  SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035

Query: 505  ASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAI 564
            +S +   + SS     +   N S  S S  SS            D +  + +     ++ 
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095

Query: 565  HNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVAT 624
             +   +S+D + S  +  S   S +  SS       S         S S+ SS +   + 
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155

Query: 625  TQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGS 684
            +  ++ S  S   + S    + SNSS ++  + S ++    D  D+S +     SS    
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215

Query: 685  LSPRSPVS 692
             S  S  S
Sbjct: 1216 SSDSSDSS 1223



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 94/474 (19%), Positives = 177/474 (37%), Gaps = 20/474 (4%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTY 267
            S+ S D S S +SS S D     +       ++    +      S     S   +     
Sbjct: 826  SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885

Query: 268  TSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQ 327
              +SN+S S       D+ +   ++N  + S  ++S      +  S+      S++SS  
Sbjct: 886  NESSNSSDSSDSSNSSDSDSS-DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 328  RGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSY 387
                     +  +  S +S     S S +  S  SS+ S      D    +DS   ++S 
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004

Query: 388  SHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPT 447
              S  S ++   +  +S +     NS  +     S+ +  S   S  +   D  NSS   
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSS---DSSDSSDSSDSSDSSDSSDSSNSS--- 1058

Query: 448  AGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASA 507
                 + +S   + +        +  S+        N +  + S  S  S+  + S  S+
Sbjct: 1059 ---DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115

Query: 508  AGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNG 567
              S +S+S   S +   + S  S +   S   SE S       +  ++  S+  ++  + 
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175

Query: 568  -IYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQ 626
               NS+D + S     S S  S+  S S     SS       +   S  S ++ +  ++ 
Sbjct: 1176 DSSNSSDSSDS-----SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1230

Query: 627  ANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSS 680
            +N  S SS S   S    + SNSS ++  + S ++ +D +   +S++  G G++
Sbjct: 1231 SNESSDSSDSSDSS----DSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 116/585 (19%), Positives = 202/585 (34%), Gaps = 42/585 (7%)

Query: 283  EDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKS--SAHSSGQRGRKPGGGRNPGT 340
            +D  +   N +     A  +S +      GS+ KG +   S  +S        G  N G 
Sbjct: 475  DDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGN 534

Query: 341  TVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVH 400
              +  S   +G    +      SS SS  S       +DS+  +DS S    SS + D  
Sbjct: 535  DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594

Query: 401  KGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEE 460
              +S +     +S        S S+ +S      +S  D   S                +
Sbjct: 595  SSDSSNSSDSSDS--------SDSSDSSDSSDSSDSKSDSSKSE--------------SD 632

Query: 461  ETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSP 520
             +  + K   +  +         + +  N S+ S SS S  SS +S++   ++SS     
Sbjct: 633  SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692

Query: 521  TLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPN 580
            +   N S  S S  SS            D     ++ S   N+  +   NS+D + S  +
Sbjct: 693  SDSSNSSESSDSSDSS------------DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740

Query: 581  VVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPS 640
              S   S +  SS       S +       S S+ SS +   + +  ++ S  S   + S
Sbjct: 741  SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800

Query: 641  HMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQ 700
                N S+SS       S+++ +D     +S N      S   S S  S  SS     D 
Sbjct: 801  SDSSNSSDSS-----DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855

Query: 701  PGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQ 760
               S   N    + S +       S+      E    SD      S      ++    + 
Sbjct: 856  SNRSDSSNSSDSSDSSDSSNSSDSSDSSD-SNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914

Query: 761  IKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNS 820
              +  +        ++  S    +  ++ S      + S+ ++ ++DS NSS S    +S
Sbjct: 915  SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974

Query: 821  FLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVS 865
               D+S    + D + S  S+ SS + ++   +  S +   S  S
Sbjct: 975  DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 104/505 (20%), Positives = 174/505 (34%), Gaps = 22/505 (4%)

Query: 208  SNRSYDQSLSDSSSH--SQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLTVTTEK 265
            S+ S D     S S   S D   + +       D            S     S   +   
Sbjct: 616  SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675

Query: 266  TYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSS 325
              +S+S++S S       D++    +++  + S   SS    S    S      +S+ SS
Sbjct: 676  DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735

Query: 326  GQRGRKPGGGRNPGTTVSAASPFPQGSFS-----GTPGSVKSSSGSSVQSPQDFLSFTDS 380
                       +  +  S +S     S S      +  S  S S +S  S     S   S
Sbjct: 736  DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795

Query: 381  DLRNDS-YSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGD 439
            D  N S  S+S  SS + D    +S +     NS  +     S+ +  S   S + S  D
Sbjct: 796  DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS-DGSDSD 854

Query: 440  LGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSAS 499
              N S  +     + +S     +        N+ S         N +  + S  S SS S
Sbjct: 855  SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914

Query: 500  PTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSE 559
              SS +S +   ++SS   + +   N S  S S  SS              +  ++  S+
Sbjct: 915  SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS-------------NSSDSSNSSD 961

Query: 560  LLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAA 619
              N+  +   NS+D + S  +  S   S +  SS      +S         S S+ SS +
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 620  PAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGS 679
               + +  ++ S  S   + S    + S+SS ++  + S ++    D  D+S +     S
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081

Query: 680  SPRGSLSPRSPVSSLQIRYDQPGNS 704
            S     S  S  S      D   +S
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSS 1106



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 90/457 (19%), Positives = 162/457 (35%), Gaps = 19/457 (4%)

Query: 199  SKLKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPS 258
            S  +     S+ S D S S +SS S D     E     +              S     S
Sbjct: 855  SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914

Query: 259  -----LTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGS 313
                  + ++E + +S ++NS   S       ++  +N++    S+ +S+  D S++  S
Sbjct: 915  SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974

Query: 314  EGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQD 373
            +     +S+ SS           +  +  S +S     S S       +SS SS  S   
Sbjct: 975  DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS- 1033

Query: 374  FLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSF 433
                +DS   +DS   S  S ++   +  +S       +S  +     S+ +  S   S 
Sbjct: 1034 ----SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089

Query: 434  ENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
             ++  D  +SS  +     + +S   + +        +  S         N +  + S  
Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149

Query: 494  SVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP 553
            S  S+  + S  S+  S +S S   S +   + S  S     S   S+ S       +  
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209

Query: 554  TTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPS 613
            ++  S+  ++  +   +S+D + S  N  S S  S+  S S     SS       + S S
Sbjct: 1210 SSDSSDSSDSSDSS--DSSDSSDS--NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDS 1265

Query: 614  AVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSS 650
               S + + +    N  S S      S   G+ SN S
Sbjct: 1266 NDESDSQSKSGNGNNNGSDSD-----SDSEGSDSNHS 1297



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 115/637 (18%), Positives = 206/637 (32%), Gaps = 50/637 (7%)

Query: 273 NSISGSLKRLEDTTARFTNANFQEVSAHTS-SGKDVSETRGS-------EGKGKKSSAHS 324
           NS     K  E T     +A         S +G D  E  GS        G GK SS +S
Sbjct: 218 NSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNS 277

Query: 325 SGQRGRKPGGGRNPGTTVSAASPF-----------PQGSFSGTPGSVKSSSGSSVQSPQD 373
            GQ G+  G   +  +++   S             P     G   S    + + +     
Sbjct: 278 KGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNG 337

Query: 374 FLSFTDSDLRNDSYSHSQQSSATKDVHKGESG-SQEGGVNSFSTLIGLPSTSAVTSQPKS 432
                D+   N   S   ++  TK+      G SQ+ G+       G  + +    +   
Sbjct: 338 SQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNE 397

Query: 433 FENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE--NV 490
            +   G  G   +   G  + Q   +  E   +K   GNK      G    +   +  + 
Sbjct: 398 GKEDKGQHG--MILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDF 455

Query: 491 SHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDG 550
              S+    P SS  S      +S    + +   + S  S     +  GS+       D 
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDS 515

Query: 551 ACPTTTFSELLNAIHNG------------------------IYNSNDVAVSFPNVVSGSG 586
              + T +   N   N                           NS+D + S  +  S S 
Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575

Query: 587 SSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNR 646
           SS+   SS      S       + + S  S ++ +  ++ ++  S S    + S    + 
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635

Query: 647 SNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSL 706
           S+S   +  + S ++  + D  D+S +     SS     S  S  S      D   +S  
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695

Query: 707 ENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTA 766
            N    + S +   +   S+         + SD      S       +        N + 
Sbjct: 696 SNSSESSDSSDS-SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754

Query: 767 KKERLQLLN-AQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDN 825
             +     N +  S    +  ++ S +      S+ ++ ++DS NSS S +  +S    +
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814

Query: 826 SLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGS 862
           S    + + + S  S+ SS + ++   +  S +  GS
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851


>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
          Length = 813

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 47/139 (33%), Positives = 67/139 (48%), Gaps = 17/139 (12%)

Query: 5   DRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHG---------CSVAVHQAC 55
           D  V+ E +    + EM   C + S+E      P  + +  G         C V VH +C
Sbjct: 673 DEVVTSEGKTKPLIPEM---CFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASC 729

Query: 56  YGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQ 113
           YGI   ++  G W C +C+    A    C LC  + GALK+T N  WAHV+CA+ +PEV+
Sbjct: 730 YGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVR 786

Query: 114 FANVSTMEPIVLQSVPHDR 132
           F NV     I +  +P  R
Sbjct: 787 FTNVPERTQIDVGRIPLQR 805


>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
          Length = 835

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 47/139 (33%), Positives = 67/139 (48%), Gaps = 17/139 (12%)

Query: 5   DRPVSLEDEVSHSMKEMIGGCCVCSDERGWAENPLVYCDGHG---------CSVAVHQAC 55
           D  V+ E +    + EM   C + S+E      P  + +  G         C V VH +C
Sbjct: 695 DEVVTSEGKTKPLIPEM---CFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASC 751

Query: 56  YGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQ 113
           YGI   ++  G W C +C+    A    C LC  + GALK+T N  WAHV+CA+ +PEV+
Sbjct: 752 YGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVR 808

Query: 114 FANVSTMEPIVLQSVPHDR 132
           F NV     I +  +P  R
Sbjct: 809 FTNVPERTQIDVGRIPLQR 827


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 164/805 (20%), Positives = 285/805 (35%), Gaps = 120/805 (14%)

Query: 206 RGSNRSYDQSLSDSSSHS-----QDKHHEKEKKKYKEKDKHKQKHKKQPEPSPALVPSLT 260
           + S  S   +L+ +S HS     +  H           ++ K  H      +  ++P+ +
Sbjct: 27  KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGS 86

Query: 261 VTTEKTYTSTSNNSISGSLKR-----------LEDTTARFTNANFQEVSAH-----TSSG 304
             +     ST +   SGS++            L + +  F ++     + H     TSSG
Sbjct: 87  TPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG 146

Query: 305 KDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSS 364
                T      G   S H++   G     G +  +T S +SP P  +      +  SS 
Sbjct: 147 VSEESTTSHSRPG---STHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSL 203

Query: 365 GSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVH------------------KGESGS 406
           G    +       T++ L  D+ + S    A+  VH                  +GES +
Sbjct: 204 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 263

Query: 407 QEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK-RAQTSGIEEETVKE 465
                +S  T    P+T++   +P +  +       SS+PT     R+ TSG+ EE+   
Sbjct: 264 FHSWPSSKDTRPAPPTTTSAFVEPSTTSHG----SPSSIPTTHISARSTTSGLVEESTTY 319

Query: 466 KKRKGNKQSKHGP--GRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLL 523
               G+ Q+ H P      G   +   SH     +S T +++SA    T+S+L + PT  
Sbjct: 320 HSSPGSTQTMHFPESDTTSGRGEESTTSH-----SSTTHTISSAPS--TTSALVEEPT-- 370

Query: 524 RNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDV---AVSFPN 580
                   S  SSP GS  +  +    +  T+  SE   A H+    +  +   A S  +
Sbjct: 371 --------SYHSSP-GSTATTHF--PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTS 419

Query: 581 VVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAV----SSAAPAVATTQANTLSGSSLS 636
           V+ G  +++P+SS  +   +         LS  +     S  +PA   + A+T S     
Sbjct: 420 VLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSE 479

Query: 637 QAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQI 696
           ++ +    +RS        A  ++  T       SR+     SSP  + +   P S+   
Sbjct: 480 ESTT----SRSRPGSTHTTAFPDSTTTP----GLSRHSTTSHSSPGSTDTTLLPASTTTS 531

Query: 697 RYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRR 756
              Q   +S  +      ++        S GQ+       P        S H     +  
Sbjct: 532 GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPG-------STHTTLFPDST 584

Query: 757 LEEQIKNLTAKKERLQLLNAQLSVPFPTITANP-----------SPSHQIHTFSAQTAPT 805
               I   + +           S   P  T +P           S + Q H  S  T P+
Sbjct: 585 TSSGIVEASTR--------VHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 636

Query: 806 -----TDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQ 860
                T  +  S + H      P    P  +   T+SG S  S+   S+P  +G +P+  
Sbjct: 637 PPSTATAPVEESTTYHRSPGSTPTTHFPASS---TTSGHSEKSTIFHSSPDASGTTPSSA 693

Query: 861 GSGVS--GVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNG 918
            S  S  G    + ++ G+      P ++T P +S       + P +           + 
Sbjct: 694 HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL 753

Query: 919 VMQTPVTMSQNPTPLTHTTVPPNAT 943
            +    T S++    TH+TV P +T
Sbjct: 754 GVGEESTTSRSQPGSTHSTVSPAST 778



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 145/622 (23%), Positives = 219/622 (35%), Gaps = 107/622 (17%)

Query: 298 SAHTSSGKDVSETRGSEGKGKKSSAHS-SGQRGRKPGGGRNPGTTVSAASPFPQGSFSGT 356
           S HT+     S TR    +G+ ++ HS    +  +P     P TT SA    P  +  G+
Sbjct: 244 SPHTTLSPAGSTTR----QGESTTFHSWPSSKDTRPA----PPTTTSAFVE-PSTTSHGS 294

Query: 357 PGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGES----GSQEGGVN 412
           P S+ ++  S+          T S L  +S ++     +T+ +H  ES    G  E    
Sbjct: 295 PSSIPTTHISARS--------TTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 346

Query: 413 SFS----TLIGLPST-SAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKK 467
           S S    T+   PST SA+  +P S+ +SPG    +  P +    + TSG  EE      
Sbjct: 347 SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS----STTSGRSEE------ 396

Query: 468 RKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTL-LRNG 526
                                  S  S SS   T ++   A S TS  L +S T  + +G
Sbjct: 397 -----------------------STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 433

Query: 527 SLQSLSVGSS---PVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVS 583
           S+++ ++  S   P  SE S  +      P TT S   +   +G+   +  + S P    
Sbjct: 434 SMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSP-ASTTSSGVSEESTTSRSRP---- 488

Query: 584 GSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMY 643
           GS  +T    S      S H         S  S ++P   +T    L  S+ +  PS   
Sbjct: 489 GSTHTTAFPDSTTTPGLSRH---------STTSHSSP--GSTDTTLLPASTTTSGPSQES 537

Query: 644 GNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSS----LQIRYD 699
               +SS +   A S  + T    G  S        S   +L P S  SS       R  
Sbjct: 538 TTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVH 597

Query: 700 QPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEE 759
               S    L P +++   L     +          TPS       S     VE      
Sbjct: 598 SSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP-----PSTATAPVEESTTYH 652

Query: 760 QIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGN 819
           +    T               P  + T+  S    I   S   + TT S   S +   G 
Sbjct: 653 RSPGSTPTTH----------FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 702

Query: 820 SFLP-----DNSLPVLNQDLTSSGQSTSSSSALSTP--PPAGQSPAQQGS-GVSGVQQVN 871
           S           +  L    T+ G S +S++  S+P  P    SPA   S GV      +
Sbjct: 703 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 762

Query: 872 GVTVGALASGMQPVTSTIPAVS 893
               G+  S + P ++T P +S
Sbjct: 763 RSQPGSTHSTVSPASTTTPGLS 784



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 176/781 (22%), Positives = 290/781 (37%), Gaps = 137/781 (17%)

Query: 257  PSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGK 316
            P+ T TT  T  ST++          E++TA      F    A T +G   + T    G+
Sbjct: 823  PASTHTTLFTEDSTTSGLT-------EESTA------FPGSPASTQTGLPATLTTADLGE 869

Query: 317  GKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGT-----PGSVKSSSGS----- 366
               +   SSG  G K    R+  + +   S   + S S T     PGS  + S S     
Sbjct: 870  ESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT 929

Query: 367  ---SVQSPQDFLS---FTDSDLRNDSY-SHSQ----------QSSATKDVHKGESGSQEG 409
               S +SP   LS    T S +  +S  SHSQ           S+ T D+ +  + S   
Sbjct: 930  FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSS 989

Query: 410  GVNSFSTLI-GLPSTSAVTSQPKSFENSPGDLGNSSLP----TAGYKRAQT--------- 455
              ++ +TL  G  + S++  Q  +F +SPGD   + LP    T+G   A T         
Sbjct: 990  QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL 1049

Query: 456  -----------SGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSV 504
                       +G++EE+   +    +  +   P        + + ++ S  S++PT+  
Sbjct: 1050 HTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF 1109

Query: 505  ASAAGSI----TSSSLQKSP-----TLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTT 555
            ++++ ++     S+++  SP      L    S  S+ VG  P  S IS       A P +
Sbjct: 1110 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE-PTTSPISSGSTETTALPGS 1168

Query: 556  TFSELLNAIHNGIYNSN---DVAVSFPNVVSGSGSSTPVSSSHLPQQSS------GHLQQ 606
            T +  L+      Y+S    D  +S P   + SG S   ++SH    S+      G    
Sbjct: 1169 TTTAGLSEKSTTFYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 1227

Query: 607  VGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQD 666
             G    S  S ++P    T  +  S ++ S  P     + S  S    +    +N T   
Sbjct: 1228 PGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLP--DNTTASG 1285

Query: 667  LGDNSRNLVGRGSSPRGSLSPR-SPVSSLQIRYDQPGNSSLENLPP----VAASIEQLLE 721
            L + S  +     SP  +LSP  S     +    Q   SS + +P      +A +E    
Sbjct: 1286 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1345

Query: 722  RQWSEGQQFLLEQGTPSDILGMLK---SLHQLQVENRRLEEQIKNLTAKKERLQLLNAQL 778
               S            S  LG  +   ++H   V         ++ T+    ++   A  
Sbjct: 1346 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGL--VEESTAYH 1403

Query: 779  SVPFPTIT---------------ANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP 823
            S P  T T               +  S S   HT S+  + T+  +    S H     + 
Sbjct: 1404 SSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIA 1463

Query: 824  DNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQ 883
                P   +  T+SG+S  S+++ S+P   G +P       SG  ++   T   ++ G  
Sbjct: 1464 TTHFP---ESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG--RIAESTTFYISPGSM 1518

Query: 884  PV----TSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVP 939
                  T+T P +SA   I        L  + +VG        P T   +P+P T+TT+ 
Sbjct: 1519 ETTLASTATTPGLSAKSTI--------LYTSDLVG-------EPTTFYISPSP-TYTTLF 1562

Query: 940  P 940
            P
Sbjct: 1563 P 1563



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 108/496 (21%), Positives = 175/496 (35%), Gaps = 72/496 (14%)

Query: 245  HKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSG 304
            H    +    L+P  T+T+     ST  +S +GSL     T A  T+A  QE S    S 
Sbjct: 1015 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL-HTTLTPASSTSAGLQEESTTFQSW 1073

Query: 305  KDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVS--AASPFPQGSFSGTPGSVKS 362
               S+T  S                        PGTT +    S       S TP +  S
Sbjct: 1074 PSSSDTTPSP-----------------------PGTTAAPVEVSTTYHSRPSSTPTTHFS 1110

Query: 363  SSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPS 422
            +S +++   ++  +   S     +     +S+ +  V +  +     G    + L G  +
Sbjct: 1111 ASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTT 1170

Query: 423  TSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRP- 481
            T+ ++ +  +F +SP     +  P +      +SG+ EE+     R G+  +   PG   
Sbjct: 1171 TAGLSEKSTTFYSSPRSPDTTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPGSTT 1226

Query: 482  -KGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRN--GSLQSLSVGSSPV 538
              G   +   SH S  S   T S     GS T+SSL    T   +  GS ++  +  +  
Sbjct: 1227 MPGVSQESTASHSSPGSTDTTLS----PGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 1282

Query: 539  GS---EISMQYRHDGACPTTTFSELLNAIHNGIY-------NSNDVAVSFPNVVS----- 583
             S   E S         P TT S   +    G         +S D   + P   S     
Sbjct: 1283 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVEL 1342

Query: 584  -----GSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQA 638
                 GS SSTP +       + G  ++      + V S+  A ATT +   S +S    
Sbjct: 1343 STTSHGSPSSTPTTHFSASSTTLGRSEE-----STTVHSSPVATATTPSPARSTTSGLVE 1397

Query: 639  PSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSL---- 694
             S  Y +   S+      +S         G +  +     S+     SP S  S+L    
Sbjct: 1398 ESTAYHSSPGSTQTMHFPESSTAS-----GRSEESRTSHSSTTHTISSPPSTTSALVEEP 1452

Query: 695  QIRYDQPGNSSLENLP 710
               +  PG+ +  + P
Sbjct: 1453 TSYHSSPGSIATTHFP 1468



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 160/779 (20%), Positives = 265/779 (34%), Gaps = 123/779 (15%)

Query: 245  HKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSG 304
            H         L+P+ T T+  +  ST+++S SGS     DT                S G
Sbjct: 513  HSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGS----TDTA--------------LSPG 554

Query: 305  KDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSS 364
               + + G E     ++ HS            NPG+T +    FP  + S       +  
Sbjct: 555  STTALSFGQE----STTFHS------------NPGSTHTTL--FPDSTTSSGIVEASTRV 596

Query: 365  GSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPST- 423
             SS  SP+  LS                +S+T    +GES + +    S  T    PST 
Sbjct: 597  HSSTGSPRTTLS---------------PASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 641

Query: 424  SAVTSQPKSFENSPGDLGNSSLP----TAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPG 479
            +A   +  ++  SPG    +  P    T+G+    T                  +  G G
Sbjct: 642  TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 701

Query: 480  RPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVG 539
                ++     + ++    S T+   S A +   SS +   T L   S+ SL VG     
Sbjct: 702  ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 761

Query: 540  SEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVS---FPNVVSGSGSSTPVSSSHL 596
            S       H    P +T +  L+     +Y+S+  +     FP+  + S      ++ H 
Sbjct: 762  SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHS 821

Query: 597  PQQS------------SGHLQQVGAL--SPSAVSSAAPAVATT-----------QANTLS 631
               S            SG  ++  A   SP++  +  PA  TT            ++  +
Sbjct: 822  RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 881

Query: 632  GSSLSQAPSHMYGNRSNSSMAALIAQS------ENNQTDQDLGDNSRNLVGRGSSPRGSL 685
            G+ LS A S   G    S+ + L   S        + T   L + S        SP  +L
Sbjct: 882  GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 941

Query: 686  SPRSPVSS-----LQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDI 740
            SP +  SS         + QPG++     P    + +   E   S   Q   E  T S  
Sbjct: 942  SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE-ATLSPG 1000

Query: 741  LGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVP--------FPTITANPSPS 792
                 SL Q            +      + +     + S P          T+T   S S
Sbjct: 1001 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS 1060

Query: 793  HQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP----------DNSLPV--LNQDLTSSGQS 840
              +   S        S +++ SP  G +  P           +S P    +   T+ G+S
Sbjct: 1061 AGLQEESTTFQSWPSSSDTTPSPP-GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS 1119

Query: 841  TSSSSALSTPPPAGQS--PAQQGSGV-SGVQQVNGVTVGALASGMQPVTSTIPAVSAVGG 897
              S++  S+P   G +  P +  + V  G    + ++ G+  +   P ++T   +S    
Sbjct: 1120 EESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKST 1179

Query: 898  IIGALPGN-QLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSAS 955
               + P +    ++      +GV +   T    P   THTT  P +T  MP     S +
Sbjct: 1180 TFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS-THTTAFPGST-TMPGVSQESTA 1236



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 79/369 (21%), Positives = 129/369 (34%), Gaps = 57/369 (15%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQ-----------------KHKKQPE 250
            S RS D +LS +S+ S     E      +    H                    H     
Sbjct: 1184 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 1243

Query: 251  PSPALVPSLTVTTEKTYTSTSNNSISGSLKRL---EDTTARFTNANFQEVSAHTSSGKDV 307
                L P  T  +     ST+ +S  GS +     ++TTA         V + T S    
Sbjct: 1244 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 1303

Query: 308  SETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSA---ASPFPQGSFSGTPGSVKSSS 364
                GS  +  +S+   S    +       P TT SA    S    GS S TP +  S+S
Sbjct: 1304 LSPAGSTTRQGESTTFQSWPSSKDTMPA--PPTTTSAFVELSTTSHGSPSSTPTTHFSAS 1361

Query: 365  GSSVQSPQDFLSF----------------TDSDLRNDSYSHSQQSSATKDVHKGESG--- 405
             +++   ++  +                 T S L  +S ++     +T+ +H  ES    
Sbjct: 1362 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 1421

Query: 406  --SQEGGVNSFSTLIGLPS----TSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIE 459
              S+E   +  ST   + S    TSA+  +P S+ +SPG +  +  P    + + TSG  
Sbjct: 1422 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP----ESSTTSGRS 1477

Query: 460  EETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKS 519
            EE+        +  +      P        ++  +    SP S   + A + T+  L   
Sbjct: 1478 EESTAS---HSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAK 1534

Query: 520  PTLLRNGSL 528
             T+L    L
Sbjct: 1535 STILYTSDL 1543



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 38/172 (22%), Positives = 65/172 (37%), Gaps = 14/172 (8%)

Query: 782 FPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSF---LPDNSLPVLNQDLTSSG 838
           FP  +     S +  TF   T  T  S  S+ +     S+   L            T SG
Sbjct: 3   FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG 62

Query: 839 QSTSSSSALSTPP-------PAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPA 891
           +S  S ++ S+P        PAG +P    S + G    + ++ G++ +   P ++T P 
Sbjct: 63  RSEESKASHSSPDAMATTVLPAGSTP----SVLVGDSTPSPISSGSMETTALPGSTTKPG 118

Query: 892 VSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNAT 943
           +S       + P +    +      +  +    T S +    THTT  P +T
Sbjct: 119 LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGST 170


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 173/797 (21%), Positives = 288/797 (36%), Gaps = 135/797 (16%)

Query: 248  QPEPSPALVPSLTVTTEKTYTSTSNNSISG----SLKRLEDTT---ARFTNANFQEVSAH 300
            +P+ SP    S+  T     T+T+  S       S  R  D T   AR T++   E S  
Sbjct: 251  EPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT 310

Query: 301  TSSGKDVSETRG------SEGKGKKSSAHSSGQRGRKPGGGR---NPGTTVSAASPFPQG 351
            + S    + T          G  ++S+A  S      PG      +PGTT  ++      
Sbjct: 311  SHSRPGPTHTIAFPDSTTMPGVSQESTASHS-----IPGSTDTTLSPGTTTPSSLGPEST 365

Query: 352  SFSGTPGSVKSS--------SG---------SSVQSPQDFLSFTDSDLRNDSYSHSQQSS 394
            +F  +PG  K++        SG         SS  SP   LS + S       +  Q   
Sbjct: 366  TFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWP 425

Query: 395  ATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK--- 451
            ++KD     SG+    V   +T    PS++  T     F  S   LG+S   T  +    
Sbjct: 426  SSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTH----FSASSTTLGHSEESTPVHSSPV 481

Query: 452  ---------RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE-------NVSHLSV 495
                     R+ TSG  EE+    +  G+ Q+ H P     + + E       + +H   
Sbjct: 482  ATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS 541

Query: 496  SSASPTSSVA-----SAAGSITSSSLQKSPTL---------------------LRNGSLQ 529
            S+ S T+++A     S+ GS  ++  + S T+                     L  GS  
Sbjct: 542  STPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP 601

Query: 530  SLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNS--NDVAVSFPNVVSGSGS 587
            S+ VG S   S IS       A P +T    L+      Y+S  +      P  ++ SG 
Sbjct: 602  SVLVGDS-TPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGV 660

Query: 588  STPVSSSHLPQQSS------GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSH 641
            S   ++SH    S+      G     G    S  S ++P    T  +  S ++ S  P +
Sbjct: 661  SEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 720

Query: 642  -MYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVS---SLQIR 697
              + +R  S+   L+    +N T   L + S  +     SP  +LSP    +        
Sbjct: 721  TTFHSRPGSTETTLL---PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTF 777

Query: 698  YDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLH-QLQVENRR 756
            +  P +      PP   S         +  +      G+PS I     + H   +     
Sbjct: 778  HSWPSSKDTRPAPPTTTS---------AFVEPSTTSHGSPSSI----PTTHISARSTTSG 824

Query: 757  LEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDS--LNSSKS 814
            L E+     +     Q ++   S          + SH   T +  +AP+T S  +    S
Sbjct: 825  LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 884

Query: 815  PH-----IGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQ--SPAQQGSGV-SG 866
             H        +  PD+S        T+SG+S  S+++ S+    G    PA+  + V  G
Sbjct: 885  YHSSPGSTATTHFPDSS--------TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG 936

Query: 867  VQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTM 926
                + ++ G++ +   P ++T P +S       + P +           +  +    T 
Sbjct: 937  ESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTT 996

Query: 927  SQNPTPLTHTTVPPNAT 943
            S++    THTT  P++T
Sbjct: 997  SRSRPGSTHTTAFPDST 1013



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 177/791 (22%), Positives = 267/791 (33%), Gaps = 168/791 (21%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQ-----------------KHKKQPE 250
            S RS D +LS +S+ S     E      +    H                    H     
Sbjct: 3254 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 3313

Query: 251  PSPALVPSLTVTTEKTYTSTSNNSISGSLKRL---EDTTARFTNANFQEVSAHTSSGKDV 307
                L P  T  +     ST+ +S  GS +     ++TTA         V + T S    
Sbjct: 3314 TDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 3373

Query: 308  SETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSA---ASPFPQGSFSGTPGSVKSSS 364
                GS  +  +S+   S    +       P TT SA    S    GS S TP +  S+S
Sbjct: 3374 LSPAGSTTRQGESTTFQSWPNSKDTTPA--PPTTTSAFVELSTTSHGSPSSTPTTHFSAS 3431

Query: 365  GSSVQSPQDFLSF----------------TDSDLRNDSYSHSQQSSATKDVHKGES---- 404
             +++   ++  +                 T S L  +S ++     +T+ +H  ES    
Sbjct: 3432 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 3491

Query: 405  GSQEGGVNSFS----TLIGLPST-SAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIE 459
            G  E    S S    T+   PST SA+  +P S+ +SPG    +  P +    + TSG  
Sbjct: 3492 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS----STTSGRS 3547

Query: 460  EETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKS 519
            EE                             S  S SS   T ++   A S TS  L +S
Sbjct: 3548 EE-----------------------------STASHSSQDATGTIVLPARSTTSVLLGES 3578

Query: 520  PTL-LRNGSLQSLSVGSS---PVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVA 575
             T  + +GS+++ ++  S   P  SE S  +      P TT S   +   +G+   +  +
Sbjct: 3579 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP-ASTTSSGVSEESTTS 3637

Query: 576  VSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSL 635
             S P    GS  +T    S      S H     +   S  ++  PA  TT     SGSS 
Sbjct: 3638 HSRP----GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT-----SGSSQ 3688

Query: 636  SQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQ 695
                SH      +SS +   A S  + T    G  S        S   +L P S  SS  
Sbjct: 3689 ESTTSH------SSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 3742

Query: 696  IRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQ-LQVEN 754
            +      +SS                             G+P   L    S    LQ E+
Sbjct: 3743 VEASTRVHSS----------------------------TGSPRTTLSPASSTSPGLQGES 3774

Query: 755  RRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKS 814
               +                      P  T T  PSP       S  TAP  +S    +S
Sbjct: 3775 TAFQTH--------------------PASTHT-TPSPP------STATAPVEESTTYHRS 3807

Query: 815  PHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVS--GVQQVNG 872
            P       P    P  +   T+SG S  S+   S+P  +G +P+   S  S  G    + 
Sbjct: 3808 P----GSTPTTHFPASS---TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 3860

Query: 873  VTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTP 932
            ++ G+      P ++T P +S       + P +           +  +    T S++   
Sbjct: 3861 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 3920

Query: 933  LTHTTVPPNAT 943
             TH+TV P +T
Sbjct: 3921 STHSTVSPAST 3931



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 165/765 (21%), Positives = 263/765 (34%), Gaps = 114/765 (14%)

Query: 245  HKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSG 304
            H    +    L+P  T+T+     ST  +S +GSL     T A  T+A  QE S    S 
Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL-HTTLTPASSTSAGLQEESTTFQSW 3143

Query: 305  KDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVS--AASPFPQGSFSGTPGSVKS 362
               S+T  S                        PGTT +    S       S TP +  S
Sbjct: 3144 PSSSDTTPSP-----------------------PGTTAAPVEVSTTYHSRPSSTPTTHFS 3180

Query: 363  SSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPS 422
            +S +++   ++  +   S     +     +S+ +  V +  +     G    + L G  +
Sbjct: 3181 ASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTT 3240

Query: 423  TSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRP- 481
            T+ ++ +  +F +SP     +  P +      +SG+ EE+     R G+  +   PG   
Sbjct: 3241 TAGLSEKSTTFYSSPRSPDTTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPGSTT 3296

Query: 482  -KGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRN--GSLQSLSVGSSPV 538
              G   +   SH S  S   T S     GS T+SSL    T   +  GS ++  +  +  
Sbjct: 3297 MPGVSQESTASHSSPGSTDTTLS----PGSTTASSLGPESTTFHSGPGSTETTLLPDNTT 3352

Query: 539  GS---EISMQYRHDGACPTTTFSELLNAIHNGIY-------NSNDVAVSFPNVVS----- 583
             S   E S         P TT S   +    G         NS D   + P   S     
Sbjct: 3353 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 3412

Query: 584  -----GSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQA 638
                 GS SSTP +       + G  ++      + V S+  A ATT +   S +S    
Sbjct: 3413 STTSHGSPSSTPTTHFSASSTTLGRSEE-----STTVHSSPVATATTPSPARSTTSGLVE 3467

Query: 639  PSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSL---- 694
             S  Y +   S+      +S     D   G    +     S+     S  S  S+L    
Sbjct: 3468 ESTTYHSSPGSTQTMHFPES-----DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP 3522

Query: 695  QIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQ------FLLEQGTPSDILG--MLKS 746
               +  PG+++  + P  + +  +  E   S   Q       L  + T S +LG      
Sbjct: 3523 TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 3582

Query: 747  LHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTT 806
            +    +E   L          ++     ++  S   P  T +P+ +    T S  +  +T
Sbjct: 3583 ISSGSMETTALPGSTTTPGLSEKSTTFHSSPRS---PATTLSPAST----TSSGVSEEST 3635

Query: 807  DSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSG 866
             S +   S H   +F    + P L++  T+S  S  S+     P     S + Q S  S 
Sbjct: 3636 TSHSRPGSTHT-TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTS- 3693

Query: 867  VQQVNGVTVGALASGMQPVTS----TIPAVSAVGGIIGALPGNQLAINGIVGALNGV--- 919
                +G T  AL+ G     S    +    S+ G     L  +    +GIV A   V   
Sbjct: 3694 -HSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 3752

Query: 920  -----------------MQTPVTMSQNPTPLTHTTVPPNATHPMP 947
                             +Q   T  Q     THTT  P +T   P
Sbjct: 3753 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 3797



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 159/763 (20%), Positives = 268/763 (35%), Gaps = 110/763 (14%)

Query: 245  HKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSG 304
            H    +    L+P  T+T+     ST  +S +GSL     T A  T+A  QE S    S 
Sbjct: 1528 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL-HTTLTPASSTSAGLQEESTTFQSW 1586

Query: 305  KDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVS--AASPFPQGSFSGTPGSVKS 362
               S+T  S                        PGTT +    S       S TP +  S
Sbjct: 1587 PSSSDTTPSP-----------------------PGTTAAPVEVSTTYHSRPSSTPTTHFS 1623

Query: 363  SSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPS 422
            +S +++   ++  +   S     +     +S+ +  V +  +     G    + L G  +
Sbjct: 1624 ASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTT 1683

Query: 423  TSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRP- 481
            T+ ++ +  +F +SP     +  P +      +SG+ EE+     R G+  +   PG   
Sbjct: 1684 TAGLSEKSTTFYSSPRSPDTTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPGSTT 1739

Query: 482  -KGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRN--GSLQSLSVGSSPV 538
              G   +   SH S  S   T S     GS T+SSL    T   +  GS ++  +  +  
Sbjct: 1740 MPGVSQESTASHSSPGSTDTTLS----PGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 1795

Query: 539  GS---EISMQYRHDGACPTTTFSELLNAIHNGIY-------NSNDVAVSFPNVVS----- 583
             S   E S         P TT S   +    G         +S D   + P   S     
Sbjct: 1796 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVEL 1855

Query: 584  -----GSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQA 638
                 GS SSTP +       + G  ++      + V S+  A ATT +   S +S    
Sbjct: 1856 STTSHGSPSSTPTTHFSASSTTLGRSEE-----STTVHSSPVATATTPSPARSTTSGLVE 1910

Query: 639  PSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSL---- 694
             S  Y +   S+      +S         G +  +     S+     SP S  S+L    
Sbjct: 1911 ESTAYHSSPGSTQTMHFPESSTAS-----GRSEESRTSHSSTTHTISSPPSTTSALVEEP 1965

Query: 695  QIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQ------FLLEQGTPSDILG--MLKS 746
               +  PG+++  + P  + +  +  E   S   Q       L  + T S +LG      
Sbjct: 1966 TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP 2025

Query: 747  LHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTT 806
            +    +E   L          ++     ++  S   P  T +P+ +    T S  +  +T
Sbjct: 2026 ISSGSMETTALPGSTTTPGLSEKSTTFHSSPRS---PATTLSPAST----TSSGVSEEST 2078

Query: 807  DSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSS------SALSTPPPAGQSPAQQ 860
             S +   S H   +F    + P L++  T+S  S  S+      ++ +T  P+ +S    
Sbjct: 2079 TSHSRPGSTHT-TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2137

Query: 861  GSGVSGVQQVNGVTVGALASGMQPV----------TSTIPAVSAVGGIIGA------LPG 904
             S  S    ++  +  AL+ G +            T+  P  +   GI+ A        G
Sbjct: 2138 SSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2197

Query: 905  NQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMP 947
            +         + +  +Q   T  Q     THTT  P +T   P
Sbjct: 2198 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 2240



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 145/622 (23%), Positives = 219/622 (35%), Gaps = 107/622 (17%)

Query: 298  SAHTSSGKDVSETRGSEGKGKKSSAHS-SGQRGRKPGGGRNPGTTVSAASPFPQGSFSGT 356
            S HT+     S TR    +G+ ++ HS    +  +P     P TT SA    P  +  G+
Sbjct: 757  SPHTTLSPAGSTTR----QGESTTFHSWPSSKDTRPA----PPTTTSAFVE-PSTTSHGS 807

Query: 357  PGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGES----GSQEGGVN 412
            P S+ ++  S+          T S L  +S ++     +T+ +H  ES    G  E    
Sbjct: 808  PSSIPTTHISARS--------TTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 859

Query: 413  SFS----TLIGLPST-SAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKK 467
            S S    T+   PST SA+  +P S+ +SPG    +  P +    + TSG  EE      
Sbjct: 860  SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS----STTSGRSEE------ 909

Query: 468  RKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTL-LRNG 526
                                   S  S SS   T ++   A S TS  L +S T  + +G
Sbjct: 910  -----------------------STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 946

Query: 527  SLQSLSVGSS---PVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVS 583
            S+++ ++  S   P  SE S  +      P TT S   +   +G+   +  + S P    
Sbjct: 947  SMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSP-ASTTSSGVSEESTTSRSRP---- 1001

Query: 584  GSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMY 643
            GS  +T    S      S H         S  S ++P   +T    L  S+ +  PS   
Sbjct: 1002 GSTHTTAFPDSTTTPGLSRH---------STTSHSSP--GSTDTTLLPASTTTSGPSQES 1050

Query: 644  GNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSS----LQIRYD 699
                +SS +   A S  + T    G  S        S   +L P S  SS       R  
Sbjct: 1051 TTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVH 1110

Query: 700  QPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEE 759
                S    L P +++   L     +          TPS       S     VE      
Sbjct: 1111 SSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP-----PSTATAPVEESTTYH 1165

Query: 760  QIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGN 819
            +    T               P  + T+  S    I   S   + TT S   S +   G 
Sbjct: 1166 RSPGSTPTTH----------FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 1215

Query: 820  SFLP-----DNSLPVLNQDLTSSGQSTSSSSALSTP--PPAGQSPAQQGS-GVSGVQQVN 871
            S           +  L    T+ G S +S++  S+P  P    SPA   S GV      +
Sbjct: 1216 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 1275

Query: 872  GVTVGALASGMQPVTSTIPAVS 893
                G+  S + P ++T P +S
Sbjct: 1276 RSQPGSTHSTVSPASTTTPGLS 1297



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 178/815 (21%), Positives = 273/815 (33%), Gaps = 140/815 (17%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQ-----------------KHKKQPE 250
            S RS D +LS +S+ S     E      +    H                    H     
Sbjct: 1697 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 1756

Query: 251  PSPALVPSLTVTTEKTYTSTSNNSISGSLKRL---EDTTARFTNANFQEVSAHTSSGKDV 307
                L P  T  +     ST+ +S  GS +     ++TTA         V + T S    
Sbjct: 1757 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 1816

Query: 308  SETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSA---ASPFPQGSFSGTPGSVKSSS 364
                GS  +  +S+   S    +       P TT SA    S    GS S TP +  S+S
Sbjct: 1817 LSPAGSTTRQGESTTFQSWPSSKDTMPA--PPTTTSAFVELSTTSHGSPSSTPTTHFSAS 1874

Query: 365  GSSVQSPQDFLSF----------------TDSDLRNDSYSHSQQSSATKDVHKGESG--- 405
             +++   ++  +                 T S L  +S ++     +T+ +H  ES    
Sbjct: 1875 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 1934

Query: 406  --SQEGGVNSFSTLIGLPS----TSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIE 459
              S+E   +  ST   + S    TSA+  +P S+ +SPG    +  P +    + TSG  
Sbjct: 1935 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS----STTSGRS 1990

Query: 460  EETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKS 519
            EE                             S  S SS   T ++   A S TS  L +S
Sbjct: 1991 EE-----------------------------STASHSSQDATGTIVLPARSTTSVLLGES 2021

Query: 520  PTL-LRNGSLQSLSVGSS---PVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVA 575
             T  + +GS+++ ++  S   P  SE S  +      P TT S   +   +G+   +  +
Sbjct: 2022 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSP-ASTTSSGVSEESTTS 2080

Query: 576  VSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSL 635
             S P    GS  +T    S      S H         S  S ++P   +T    L  S+ 
Sbjct: 2081 HSRP----GSTHTTAFPDSTTTPGLSRH---------STTSHSSP--GSTDTTLLPASTT 2125

Query: 636  SQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSS-- 693
            +  PS       +S  +   A S  + T    G  S        S   +L P S  SS  
Sbjct: 2126 TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 2185

Query: 694  --LQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQ 751
                 R      S    L P +++   L     +          TPS       S     
Sbjct: 2186 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP-----PSTATAP 2240

Query: 752  VENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNS 811
            VE      +    T               P  + T+  S    I   S   + TT S   
Sbjct: 2241 VEESTTYHRSPGSTPTTH----------FPASSTTSGHSEKSTIFHSSPDASGTTPSSAH 2290

Query: 812  SKSPHIGNSFLP-----DNSLPVLNQDLTSSGQSTSSSSALSTP--PPAGQSPAQQGS-G 863
            S +   G S           +  L    T+ G S +S++  S+P  P    SPA   S G
Sbjct: 2291 STTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2350

Query: 864  VSGVQQVNGVTVGALASGMQPVTSTIPAVSAVG-GIIGALPGNQLAINGIVGALNGVMQT 922
            V      +    G+  S + P ++T P +S     +  + PG+               +T
Sbjct: 2351 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGST--------ETTVFPRT 2402

Query: 923  PVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGL 957
            P T  +   P T  +  P +TH    T  ++ SGL
Sbjct: 2403 PTTSVRGEEPTTFHS-RPASTHTTLFTEDSTTSGL 2436



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 164/825 (19%), Positives = 280/825 (33%), Gaps = 139/825 (16%)

Query: 245  HKKQPEPSPALVPS----LTVTTEKTYTSTSNNSISGS---LKRLEDTTARFTN----AN 293
            + K   P+P    S    L+ T+  + +ST     S S   L R E++T   ++    A 
Sbjct: 3394 NSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 3453

Query: 294  FQEVSAHTSSGKDVSETRGSEGKGKKSSAH-----SSGQRGRKPGGGRNPGTTVSAASPF 348
                +  T+SG     T      G   + H     ++  RG +     +  T   +++P 
Sbjct: 3454 TPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPS 3513

Query: 349  PQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSS---------ATKDV 399
               +    P S  SS GS+  +     S T       + SHS Q +         +T  V
Sbjct: 3514 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 3573

Query: 400  HKGESGSQEGGVNSFST--LIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSG 457
              GES +      S  T  L G  +T  ++ +  +F +SP     +  P +      +SG
Sbjct: 3574 LLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAS----TTSSG 3629

Query: 458  IEEETVKEKKRKGNKQSKHGPGRPK--GNKNQENVSHLSVSS-------ASPTSSVASAA 508
            + EE+     R G+  +   P      G       SH S  S       AS T+S +S  
Sbjct: 3630 VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQE 3689

Query: 509  GSITSSSLQKSPTLLRNGSLQSLSVG-------SSPVGS---------------EISMQY 546
             + + SS   + T L  GS  +LS G       SSP  +               E S + 
Sbjct: 3690 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV 3749

Query: 547  RHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGS-----STPVSSS------- 594
                  P TT S   ++   G+   +    + P     + S     + PV  S       
Sbjct: 3750 HSSTGSPRTTLSPA-SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 3808

Query: 595  ------HLPQQS--SGHLQQ---------VGALSPSAVSSAAP----------AVATTQA 627
                  H P  S  SGH ++             +PS+  S             +  +T+ 
Sbjct: 3809 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 3868

Query: 628  NTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSP 687
             TL GS+ +   S       +S  +     S  + T   +G+ S     +  S   ++SP
Sbjct: 3869 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP 3928

Query: 688  RSPVS------SLQIRYDQPGNSSLENLP------------------PVAASIEQLLERQ 723
             S  +      S  +    PG++     P                  P +       E  
Sbjct: 3929 ASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDS 3988

Query: 724  WSEG--QQFLLEQGTPSDI---LGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQL 778
             + G  ++     G+P+     L    +   L  E+        +   K    +   + L
Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048

Query: 779  SVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSG 838
                     +PS +    T +   +PTT SL+   +    +   PD +L       TSSG
Sbjct: 4049 VGESTPSRLSPSSTE---TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT--TSSG 4103

Query: 839  QSTSSSSALSTPPPAGQSPAQQGSGVSGVQQ---VNGVTVGALASGMQPVTSTIPAVSAV 895
             S  SS++ S P     +     +  SG+ Q    +  + G+  + + P ++T  ++   
Sbjct: 4104 VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ 4163

Query: 896  GGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPP 940
                 + PG+          +   +    T + + T   HTT+ P
Sbjct: 4164 STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 4208



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 181/818 (22%), Positives = 282/818 (34%), Gaps = 176/818 (21%)

Query: 245  HKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSG 304
            H    +    L+P  T+T+     ST  +S +GSL     T A  T+   QE S    S 
Sbjct: 4168 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL-HTTLTPASSTSTGLQEESTTFQSW 4226

Query: 305  KDVSET--------------------RGSEGKGKKSSAHSS--GQRGRKPGGGRNPGTTV 342
               S+T                    R S       SA S+  G+         +PG T 
Sbjct: 4227 PSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 4286

Query: 343  SA----------------ASPFPQGSFSGT--PGSVKSSS--------GSSVQSPQDFL- 375
            +A                 SP   GS   T  PGS  ++          SS +SP   L 
Sbjct: 4287 TALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS 4346

Query: 376  --SFTDSDLRNDS-YSHSQ---------QSSATKDVHKGESGSQEGGVNSFSTLIGLPST 423
              S T S +  +S  SHS+          SS T      ES +      S  T +   ST
Sbjct: 4347 PASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGST 4406

Query: 424  SAVTSQPKS--FENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRP 481
            +A +  P+S  F +SPG    + LP         SG+ E +       G   S H    P
Sbjct: 4407 TASSLGPESTTFHSSPGSTETTLLP----DNTTASGLLEASTPVHSSTG---SPHTTLSP 4459

Query: 482  KGNKNQENVS--------HLSVSSASPTSSVASAAGSITS-SSLQKSPTLLRNGSL---- 528
             G+  ++  S            + A PT++ A    S TS  S   +PT   + S     
Sbjct: 4460 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 4519

Query: 529  ---QSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGS 585
               +S +V SSPV +  +          T+   E     H+   ++  +     N  SG 
Sbjct: 4520 RSEESTTVHSSPVATATTPS---PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGR 4576

Query: 586  GSSTPVSSSHLPQQSSGHLQQVGAL--SPSAVSSAAPAVATT---QANTLSGSSLSQAPS 640
            G  +  S S      S       AL   P++  S+  + ATT    ++T SG S     S
Sbjct: 4577 GEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 4636

Query: 641  HMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSL--------------- 685
            H     S+      I     + T   LG+++ + +  GS    +L               
Sbjct: 4637 H-----SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 4691

Query: 686  -------SPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTP- 737
                   +P +  S+      +   S+  +  PVA +      R  + G   L+E+ T  
Sbjct: 4692 FHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG---LVEESTAY 4748

Query: 738  SDILGMLKSLH--QLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQI 795
                G  +++H  +    + R EE                           +  S S   
Sbjct: 4749 HSSPGSTQTMHFPESSTASGRSEE---------------------------SRTSHSSTT 4781

Query: 796  HTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQ 855
            HT S+  + T+  +    S H     +     P   +  T+SG+S  S+++ S+P   G 
Sbjct: 4782 HTISSPPSTTSALVEEPTSYHSSPGSIATTHFP---ESSTTSGRSEESTASHSSPDTNGI 4838

Query: 856  SPAQQGSGVSGVQQVNGVTVGALASGMQPV----TSTIPAVSAVGGIIGALPGNQLAING 911
            +P       SG  ++   T   ++ G        T+T P +SA   I+ +      +   
Sbjct: 4839 TPLPAHFTTSG--RIAESTTFYISPGSMETTLASTATTPGLSAKSTILYS------SSRS 4890

Query: 912  IVGALNGVMQTPVTMSQNPTPL------THTTVPPNAT 943
                L+    T  ++S  PT L      THTT  P +T
Sbjct: 4891 PDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPAST 4928



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 92/451 (20%), Positives = 171/451 (37%), Gaps = 39/451 (8%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEK--DKHKQKHKKQPEPSPALVPSLTVTTEK 265
            SN +  +    ++SHS   H             ++    H      +    P  + T+ +
Sbjct: 4570 SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 4629

Query: 266  TYTSTSNNSISGS-----LKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKKS 320
            +  ST+++S   +     L     T+     +    +S+ +     +  +  + G  +KS
Sbjct: 4630 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 4689

Query: 321  SAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDS 380
            +   S            P T  SA+S     S   T  +V SS  ++  +P    S T S
Sbjct: 4690 TTFHSSPSS-------TPTTHFSASSTTLGRSEEST--TVHSSPVATATTPSPARS-TTS 4739

Query: 381  DLRNDSYSHSQQSSATKDVHKGESG-----SQEGGVNSFSTLIGLPS----TSAVTSQPK 431
             L  +S ++     +T+ +H  ES      S+E   +  ST   + S    TSA+  +P 
Sbjct: 4740 GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPT 4799

Query: 432  SFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR--PKGNKNQEN 489
            S+ +SPG +  +  P    + + TSG  EE+               P      G   +  
Sbjct: 4800 SYHSSPGSIATTHFP----ESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST 4855

Query: 490  VSHLSVSSASPT-SSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRH 548
              ++S  S   T +S A+  G    S++  S +   + +L   S+ SS +  E +  Y  
Sbjct: 4856 TFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQ 4915

Query: 549  DGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVG 608
              +  TT F    +   +G+   +    S P     + S   +++S   Q+ +    Q G
Sbjct: 4916 AESTHTTAFP--ASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPG 4973

Query: 609  ALSPSAVSSAAPAVATTQANTLSGSSLSQAP 639
                SA+S+ +PA  T    +   ++   +P
Sbjct: 4974 ----SALSTVSPASTTVPGLSEESTTFYSSP 5000



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 160/779 (20%), Positives = 265/779 (34%), Gaps = 123/779 (15%)

Query: 245  HKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSG 304
            H         L+P+ T T+  +  ST+++S SGS     DT                S G
Sbjct: 1026 HSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGS----TDTA--------------LSPG 1067

Query: 305  KDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSS 364
               + + G E     ++ HS            NPG+T +    FP  + S       +  
Sbjct: 1068 STTALSFGQE----STTFHS------------NPGSTHTTL--FPDSTTSSGIVEASTRV 1109

Query: 365  GSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPST- 423
             SS  SP+  LS                +S+T    +GES + +    S  T    PST 
Sbjct: 1110 HSSTGSPRTTLS---------------PASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154

Query: 424  SAVTSQPKSFENSPGDLGNSSLP----TAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPG 479
            +A   +  ++  SPG    +  P    T+G+    T                  +  G G
Sbjct: 1155 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 1214

Query: 480  RPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVG 539
                ++     + ++    S T+   S A +   SS +   T L   S+ SL VG     
Sbjct: 1215 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 1274

Query: 540  SEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVS---FPNVVSGSGSSTPVSSSHL 596
            S       H    P +T +  L+     +Y+S+  +     FP+  + S      ++ H 
Sbjct: 1275 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHS 1334

Query: 597  PQQS------------SGHLQQVGAL--SPSAVSSAAPAVATT-----------QANTLS 631
               S            SG  ++  A   SP++  +  PA  TT            ++  +
Sbjct: 1335 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 1394

Query: 632  GSSLSQAPSHMYGNRSNSSMAALIAQS------ENNQTDQDLGDNSRNLVGRGSSPRGSL 685
            G+ LS A S   G    S+ + L   S        + T   L + S        SP  +L
Sbjct: 1395 GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 1454

Query: 686  SPRSPVSS-----LQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDI 740
            SP +  SS         + QPG++     P    + +   E   S   Q   E  T S  
Sbjct: 1455 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE-ATLSPG 1513

Query: 741  LGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVP--------FPTITANPSPS 792
                 SL Q            +      + +     + S P          T+T   S S
Sbjct: 1514 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS 1573

Query: 793  HQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP----------DNSLPV--LNQDLTSSGQS 840
              +   S        S +++ SP  G +  P           +S P    +   T+ G+S
Sbjct: 1574 AGLQEESTTFQSWPSSSDTTPSPP-GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS 1632

Query: 841  TSSSSALSTPPPAGQS--PAQQGSGV-SGVQQVNGVTVGALASGMQPVTSTIPAVSAVGG 897
              S++  S+P   G +  P +  + V  G    + ++ G+  +   P ++T   +S    
Sbjct: 1633 EESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKST 1692

Query: 898  IIGALPGN-QLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSAS 955
               + P +    ++      +GV +   T    P   THTT  P +T  MP     S +
Sbjct: 1693 TFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS-THTTAFPGST-TMPGVSQESTA 1749



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 185/818 (22%), Positives = 292/818 (35%), Gaps = 138/818 (16%)

Query: 243  QKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTS 302
            Q H      +P+   + T   E+   ST+ +   GS        A  T +   E S    
Sbjct: 3778 QTHPASTHTTPSPPSTATAPVEE---STTYHRSPGSTPTTH-FPASSTTSGHSEKSTIFH 3833

Query: 303  SGKDVSETRGSEGKGKKSSAHSSGQ-RGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
            S  D S T         SSAHS+   RG       +PG+T     P   GS + TPG  +
Sbjct: 3834 SSPDASGTT-------PSSAHSTTSGRGESTTSRISPGSTEITTLP---GSTT-TPGLSE 3882

Query: 362  SSSG--SSVQSPQDFLS---FTDSDLRNDSYSHSQQSSATKD------------------ 398
            +S+   SS +SP   LS    T   +  +S +   Q  +T                    
Sbjct: 3883 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT 3942

Query: 399  VHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGI 458
            V+    GS E  V   ST     +TS    +P +F + P     S+  T   + + TSG+
Sbjct: 3943 VYSSSPGSTETTVFPRST-----TTSVRREEPTTFHSRPA----STHTTLFTEDSTTSGL 3993

Query: 459  EEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQK 518
             EE+        + Q+         +  +E+ +    SS+  T +  S A S TS  + +
Sbjct: 3994 TEESTAFPGSPASTQTGLPATLTTADLGEESTTF--PSSSGSTGTKLSPARSTTSGLVGE 4051

Query: 519  S-PTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVS 577
            S P+ L   S ++ ++  SP    +S +        +TTF             S D  +S
Sbjct: 4052 STPSRLSPSSTETTTLPGSPTTPSLSEK--------STTFYTSPR--------SPDATLS 4095

Query: 578  FPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQ 637
             P   + SG S   S+SH  Q  S H            ++A P   TT       S LSQ
Sbjct: 4096 -PATTTSSGVSEESSTSH-SQPGSTH------------TTAFPDSTTT-------SGLSQ 4134

Query: 638  APSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIR 697
             P+  + ++ ++        S  + T   LG  S            +L P   ++S  + 
Sbjct: 4135 EPTTSHSSQGSTEATL----SPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVE 4190

Query: 698  YDQPGNSSLENLPPV---AASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVEN 754
               P +SS  +L      A+S    L+ + +  Q +     + SD      S   + VE 
Sbjct: 4191 ASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSW----PSSSDTTPSPPSTTAVPVEV 4246

Query: 755  RRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKS 814
                    + T         +  L     + T + SP           + T+  +    +
Sbjct: 4247 STTYHSRPSSTPTTH-FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 4305

Query: 815  PHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTP--PPAGQSPAQQ-GSGVSGVQQVN 871
              I +      +LP      T++G S  S++  S+P  P    SPA    SGVS     +
Sbjct: 4306 SPISSGSTETTALP---GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 4362

Query: 872  GVTVGALASGMQPVTSTIPAVSAVGGIIGALPGN---QLAINGIVGALNGVMQTPVTMSQ 928
                G++ +   P ++T+P VS       + PG+    L+      +  G   T  T   
Sbjct: 4363 HSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPEST--TFHS 4420

Query: 929  NPTPLTHTTVPPN--------ATHPMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNS 980
            +P     T +P N        A+ P+ ++  +  + L       RQ       FQ   NS
Sbjct: 4421 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ--GESTTFQSWPNS 4478

Query: 981  QQLTPV---------------HRHPHFTQLPPTHFSPS 1003
            +  TP                H  P  T  P THFS S
Sbjct: 4479 KDTTPAPPTTTSAFVELSTTSHGSPSST--PTTHFSAS 4514



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 159/726 (21%), Positives = 259/726 (35%), Gaps = 123/726 (16%)

Query: 243  QKHKKQPEPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTS 302
            Q H      +P+   + T   E+   ST+ +   GS        A  T +   E S    
Sbjct: 2221 QTHPASTHTTPSPPSTATAPVEE---STTYHRSPGSTPTTH-FPASSTTSGHSEKSTIFH 2276

Query: 303  SGKDVSETRGSEGKGKKSSAHSSGQ-RGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
            S  D S T         SSAHS+   RG       +PG+T     P   GS + TPG  +
Sbjct: 2277 SSPDASGTT-------PSSAHSTTSGRGESTTSRISPGSTEITTLP---GSTT-TPGLSE 2325

Query: 362  SSSG--SSVQSPQDFLS---FTDSDLRNDSYSHSQQSSATKDVHKGES----GSQEGGVN 412
            +S+   SS +SP   LS    T   +  +S +   Q  +T       S    G  E    
Sbjct: 2326 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT 2385

Query: 413  SFSTLIG---------LPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETV 463
             +S+  G          P+TS    +P +F + P     S+  T   + + TSG+ EE+ 
Sbjct: 2386 VYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPA----STHTTLFTEDSTTSGLTEEST 2441

Query: 464  KEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKS-PTL 522
                   + Q+         +  +E+ +    SS+  T +  S A S TS  + +S P+ 
Sbjct: 2442 AFPGSPASTQTGLPATLTTADLGEESTTF--PSSSGSTGTTLSPARSTTSGLVGESTPSR 2499

Query: 523  LRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVV 582
            L   S ++ ++  SP    +S +        +TTF           Y S       P   
Sbjct: 2500 LSPSSTETTTLPGSPTTPSLSEK--------STTF-----------YTS-------PRSP 2533

Query: 583  SGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHM 642
              + S    +SS + ++SS    Q G+   +A   +      ++ +T S SS     + +
Sbjct: 2534 DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 2593

Query: 643  YGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPG 702
                + +S       S+ + T      ++   +  GS+   S    S        +  PG
Sbjct: 2594 LPASTTTS-----GPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTF-----HSSPG 2643

Query: 703  NSSLENLPPVAAS--IEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQ-LQVENRRLEE 759
            ++     P    S  I +   R  S         G+P   L    S    LQ E+   + 
Sbjct: 2644 STHTTLFPDSTTSSGIVEASTRVHSS-------TGSPRTTLSPASSTSPGLQGESTTFQT 2696

Query: 760  QIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGN 819
                                 P  T T  PSP       S  TAP  +S    +SP    
Sbjct: 2697 H--------------------PASTHTT-PSPP------STATAPVEESTTYHRSP---- 2725

Query: 820  SFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVS--GVQQVNGVTVGA 877
               P    P  +   T+SG S  S+   S+P  +G +P+   S  S  G    + ++ G+
Sbjct: 2726 GSTPTTHFPASS---TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 2782

Query: 878  LASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTT 937
                  P ++T P +S       + P +           +  +    T S++    TH+T
Sbjct: 2783 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST 2842

Query: 938  VPPNAT 943
            V P +T
Sbjct: 2843 VSPAST 2848



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 144/726 (19%), Positives = 250/726 (34%), Gaps = 93/726 (12%)

Query: 253  PALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRG 312
            PA + +  +  E T   +S+ S   +L     TT+         V   T S    S T  
Sbjct: 2455 PATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL-------VGESTPSRLSPSSTET 2507

Query: 313  SEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQ 372
            +   G  ++   S +        R+P  T+S A+    G       S +SS+  S     
Sbjct: 2508 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV------SEESSTSHSQPGST 2561

Query: 373  DFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKS 432
               +F DS        HS  S ++        GS +  +   ST    PS  + TS    
Sbjct: 2562 HTTAFPDSTTTPGLSRHSTTSHSSP-------GSTDTTLLPASTTTSGPSQESTTSH--- 2611

Query: 433  FENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSH 492
              +SPG    +  P  G   A + G E  T       G+  +   P     +   E  + 
Sbjct: 2612 --SSPGSTDTALSP--GSTTALSFGQESTTFHSSP--GSTHTTLFPDSTTSSGIVEASTR 2665

Query: 493  LSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGS-----EISMQYR 547
            +  S+ SP ++++ A  S TS  LQ   T  +     + +  S P  +     E +  +R
Sbjct: 2666 VHSSTGSPRTTLSPA--SSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHR 2723

Query: 548  HDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQV 607
              G+ PTT F    ++  +G    + +  S P+      S T  SS+H      G     
Sbjct: 2724 SPGSTPTTHFPA--SSTTSGHSEKSTIFHSSPDA-----SGTTPSSAHSTTSGRGE---- 2772

Query: 608  GALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDL 667
                 S  S  +P   +T+  TL GS+ +   S       +S  +     S  + T   +
Sbjct: 2773 -----STTSRISPG--STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGV 2825

Query: 668  GDNSRNLVGRGSSPRGSLSPRSPVS------SLQIRYDQPGNSSLENLP----------- 710
            G+ S     +  S   ++SP S  +      S  +    PG++     P           
Sbjct: 2826 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEE 2885

Query: 711  -------PVAASIEQLLERQWSEG--QQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQI 761
                   P +       E   + G  ++     G+P+     L +     +    L E+ 
Sbjct: 2886 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPAT----LTTADLGEES 2941

Query: 762  KNLTAKKERLQLLNAQLSVPFPTITANPSPSH----QIHTFSAQTAPTTDSLNSSKSPHI 817
                +         +        +    +PS        T +   +PTT SL+   +   
Sbjct: 2942 TTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY 3001

Query: 818  GNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQ---VNGVT 874
             +   PD +L       TSSG S  SS++ S P     +     +  SG+ Q    +  +
Sbjct: 3002 TSPRSPDATLSPATT--TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSS 3059

Query: 875  VGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLT 934
             G+  + + P ++T  ++        + PG+          +   +    T + + T   
Sbjct: 3060 QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL 3119

Query: 935  HTTVPP 940
            HTT+ P
Sbjct: 3120 HTTLTP 3125



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 94/445 (21%), Positives = 164/445 (36%), Gaps = 57/445 (12%)

Query: 257  PSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDV--SETRGSE 314
            P  + TT  +  ST++     +  R+   +   T       +   S       S  R   
Sbjct: 2753 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 2812

Query: 315  GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPG------SVKSSSGSSV 368
                 +S  S G           PG+T S  SP    + + TPG      +V SSS  S 
Sbjct: 2813 TTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP----ASTTTPGLSEESTTVYSSSPGST 2868

Query: 369  QSPQDFLSFTDSDLRNDSYS--HSQQSSATKDVHKGES---GSQEGGV----NSFSTLIG 419
            ++   F   T + +R +  +  HS+ +S    +   +S   G  E       +  ST  G
Sbjct: 2869 ETTV-FPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 2927

Query: 420  LPSTSAVTS---QPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKH 476
            LP+T        +  +F +S G  G +  P     R+ TSG+  E+   +    + ++  
Sbjct: 2928 LPATLTTADLGEESTTFPSSSGSTGTTLSPA----RSTTSGLVGESTPSRLSPSSTETTT 2983

Query: 477  GPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSS 536
             PG P      E  +    S  SP ++++ A  + +  S + S +  + GS  + +   S
Sbjct: 2984 LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 3043

Query: 537  PVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHL 596
               S +S +       PT + S            S +  +S        GS+T   +S L
Sbjct: 3044 TTTSGLSQE-------PTASHSS---------QGSTEATLS-------PGSTT---ASSL 3077

Query: 597  PQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIA 656
             QQS+      G    + +          +A+T + SS      H     ++S+ A L  
Sbjct: 3078 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL--HTTLTPASSTSAGLQE 3135

Query: 657  QSENNQTDQDLGDNSRNLVGRGSSP 681
            +S   Q+     D + +  G  ++P
Sbjct: 3136 ESTTFQSWPSSSDTTPSPPGTTAAP 3160



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 125/619 (20%), Positives = 207/619 (33%), Gaps = 60/619 (9%)

Query: 333 GGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQ 392
           GG     +T S++ PF   +FS    SV   +GS+         F DS   +    HS++
Sbjct: 174 GGNTTSASTPSSSDPFT--TFSDYGVSVTFITGSTATK-----HFLDSSTNS---GHSEE 223

Query: 393 SSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKR 452
           S+ +         +     ++ S  +G P TS +TS        PG     S  TAG   
Sbjct: 224 STVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPG-----STTTAGLSE 278

Query: 453 AQTSGIEEETVKEKKRKGNKQSKHGPG-RPKGNKNQENVSHLSVSSASPTSSVASAAGSI 511
             T+        ++     + +  G   +   + ++   +H      S T    S   + 
Sbjct: 279 KSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTA 338

Query: 512 TSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP-TTTFSELLNAIHNGIYN 570
           + S    + T L  G+    S+G        S  Y      P  TT S LL A       
Sbjct: 339 SHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEA------- 391

Query: 571 SNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTL 630
                 S P V S +GS     S        G      +   S  +S AP+  TT A   
Sbjct: 392 ------STP-VHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPS-GTTSAFVK 443

Query: 631 SGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSP 690
             ++   +PS       ++S   L    E+         +S  +    + P    +    
Sbjct: 444 LSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV------HSSPVATATTPPPARSATSGH 497

Query: 691 VSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQL 750
           V      +  PG++   + P  + +     E     G     +  TPS    +  + +  
Sbjct: 498 VEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHS 557

Query: 751 QVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLN 810
            + +       ++ +    R +   A  S P    T             A + P+    +
Sbjct: 558 SLGSTETTH-FRDSSTISGRSEESKASHSSPDAMATT---------VLPAGSTPSVLVGD 607

Query: 811 SSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTP--PPAGQSPAQQ-GSGVSGV 867
           S+ SP I +  +   +LP      T  G S  S++  S+P  P     PA    SGVS  
Sbjct: 608 STPSP-ISSGSMETTALP---GSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEE 663

Query: 868 QQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPG---NQLAINGIVGALNGVMQTPV 924
              +    G+  +   P ++T+P +S       + PG     L+      +  G   T  
Sbjct: 664 STTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYT-- 721

Query: 925 TMSQNPTPLTHTTVPPNAT 943
           T    P     T +P N T
Sbjct: 722 TFHSRPGSTETTLLPDNTT 740



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 53/243 (21%), Positives = 88/243 (36%), Gaps = 43/243 (17%)

Query: 788 NPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSAL 847
           +P  S  + T +   + TT  L+   +    +   PD +L       TSSG S  S+++ 
Sbjct: 255 SPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPART--TSSGVSEKSTTSH 312

Query: 848 STPPPAGQSPAQQGSGVSGVQQVNGVT---VGALASGMQPVTSTIPAVSAVGGIIGALPG 904
           S P P         + + GV Q +  +    G+  + + P T+T  ++        + PG
Sbjct: 313 SRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPG 372

Query: 905 --------NQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNA-------------- 942
                   +    +G++ A      TPV  S   T   HTT+ P++              
Sbjct: 373 YTKTTRLPDNTTTSGLLEA-----STPVHSS---TGSPHTTLSPSSSTTHEGEPTTFQSW 424

Query: 943 -----THPMPATLTNSASGLGLL---SDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQ 994
                T P P+  T++   L      S               L +S++ TPVH  P  T 
Sbjct: 425 PSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA 484

Query: 995 LPP 997
             P
Sbjct: 485 TTP 487


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 168/749 (22%), Positives = 273/749 (36%), Gaps = 126/749 (16%)

Query: 262  TTEKTYTSTSNNSISGSLKRLEDT--TARFTNANFQEVSA--HTSSGKDVS----ETRGS 313
            TT   +   S  S  GS   +  T  +AR T +   E S   H+S G   +    E+  +
Sbjct: 713  TTTSAFVEPSTTS-HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT 771

Query: 314  EGKGKKSS-AHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQ 372
             G+G++S+ +HSS               T+S+A P    +    P S  SS GS+  +  
Sbjct: 772  SGRGEESTTSHSSTTH------------TISSA-PSTTSALVEEPTSYHSSPGSTATTHF 818

Query: 373  DFLSFTDSDLRNDSYSHSQQSS---------ATKDVHKGESGSQEGGVNSFST--LIGLP 421
               S T         SHS Q +         +T  V  GES +      S  T  L G  
Sbjct: 819  PDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGST 878

Query: 422  STSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRP 481
            +T  ++ +  +F +SP     +  P +      +SG+ EE+     R G   S H    P
Sbjct: 879  TTPGLSERSTTFHSSPRSPATTLSPAS----TTSSGVSEESTTSHSRPG---STHTTAFP 931

Query: 482  KGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSE 541
                      H + S +SP S+  +   + T++ L   PT             +SP+ S 
Sbjct: 932  DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPT-------------TSPISSG 978

Query: 542  ISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSS 601
             +      G+  T   SE     ++    S D  +S P   + SG S   ++SH    S+
Sbjct: 979  STETTALPGSTTTAGLSEKSTTFYSSP-RSPDTTLS-PASTTSSGVSEESTTSHSRPGST 1036

Query: 602  ------GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAP-SHMYGNRSNSSMAAL 654
                  G     G    S  S ++P    T  +  S ++ S  P S  + +   S+   L
Sbjct: 1037 HTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTL 1096

Query: 655  IAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPR-SPVSSLQIRYDQPGNSSLENLPPVA 713
            +    +N T   L + S  +     SPR +LSP  S     +    Q   SS + +P   
Sbjct: 1097 LP---DNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPP 1153

Query: 714  ASIEQLLERQWSEGQQFLLEQGTPSDI-----------LGMLK---SLHQLQVENRRLEE 759
             +    +E   +         G+PS I            G  +   ++H   V       
Sbjct: 1154 TTTSAFVELSTTS-------HGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPS 1206

Query: 760  QIKNLTAKKERLQLLNAQLSVPFPTIT---------------ANPSPSHQIHTFSAQTAP 804
              ++ T+    ++   A  S P  T T               +  S S   HT S+  + 
Sbjct: 1207 PARSTTSGL--VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 1264

Query: 805  TTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGV 864
            T+  +    S H     +     P   +  T+SG+S  S+++ S+P   G +P       
Sbjct: 1265 TSALVEEPTSYHSSPGSIATTHFP---ESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 1321

Query: 865  SGVQQVNGVTVGALASGMQPV----TSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVM 920
            SG  ++   T   ++ G        T+T P +SA   I+ +      +       L+   
Sbjct: 1322 SG--RIAESTTFYISPGSMETTLASTATTPGLSAKSTILYS------SSRSPDQTLSPAS 1373

Query: 921  QTPVTMSQNPTPL------THTTVPPNAT 943
             T  ++S  PT L      THTT  P +T
Sbjct: 1374 MTSSSISGEPTSLYSQAESTHTTAFPAST 1402



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 173/797 (21%), Positives = 286/797 (35%), Gaps = 135/797 (16%)

Query: 248 QPEPSPALVPSLTVTTEKTYTSTSNNSISG----SLKRLEDTT---ARFTNANFQEVSAH 300
           +P+ SP    S+  T     T+T+  S       S  R  D T   AR T++   E S  
Sbjct: 172 EPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT 231

Query: 301 TSSGKDVSETRG------SEGKGKKSSAHSSGQRGRKPGGGR---NPGTTVSAASPFPQG 351
           + S    + T          G  ++S+A  S      PG      +PGTT  ++      
Sbjct: 232 SHSRPGPTHTIAFPDSTTMPGVSQESTASHS-----IPGSTDTTLSPGTTTPSSLGPEST 286

Query: 352 SFSGTPGSVKSS--------SG---------SSVQSPQDFLSFTDSDLRNDSYSHSQQSS 394
           +F  +PG  K++        SG         SS  SP   LS   S       +  Q   
Sbjct: 287 TFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWP 346

Query: 395 ATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK--- 451
           ++KD     SG+    V   +T    PS++  T     F  S   LG+S   T  +    
Sbjct: 347 SSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTH----FSASSTTLGHSEESTPVHSSPV 402

Query: 452 ---------RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE-------NVSHLSV 495
                    R+ TSG  EE+    +  G+ Q+ H P     + + E       + +H   
Sbjct: 403 ATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS 462

Query: 496 SSASPTSSVA-----SAAGSITSSSLQKSPTL---------------------LRNGSLQ 529
           S+ S T+++A     S+ GS  ++  + S T+                     L  GS  
Sbjct: 463 STPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP 522

Query: 530 SLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNS--NDVAVSFPNVVSGSGS 587
           S+ VG S   S IS       A P +T    L+      Y+S  +      P  ++ SG 
Sbjct: 523 SVLVGDS-TPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGV 581

Query: 588 STPVSSSHLPQQSS------GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSH 641
           S   ++SH    S+      G     G    S  S ++P    T  +  S ++ S  P +
Sbjct: 582 SEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 641

Query: 642 -MYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVS---SLQIR 697
             + +R  S+   L+    +N T   L + S  +     SP  +LSP    +        
Sbjct: 642 TTFHSRPGSTETTLL---PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTF 698

Query: 698 YDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLH-QLQVENRR 756
           +  P ++     PP   S         +  +      G+PS I     + H   +     
Sbjct: 699 HSWPSSNDTRPAPPTTTS---------AFVEPSTTSHGSPSSI----PTTHISARSTTSG 745

Query: 757 LEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDS--LNSSKS 814
           L E+     +     Q ++   S          + SH   T +  +AP+T S  +    S
Sbjct: 746 LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 805

Query: 815 PH-----IGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQ--SPAQQGSGV-SG 866
            H        +  PD+S        T+SG+S  S ++ S+    G    PA+  + V  G
Sbjct: 806 YHSSPGSTATTHFPDSS--------TTSGRSEESIASHSSQDATGTIVLPARSTNSVLLG 857

Query: 867 VQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTM 926
               + ++ G++ +   P ++T P +S       + P +           +  +    T 
Sbjct: 858 ESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTT 917

Query: 927 SQNPTPLTHTTVPPNAT 943
           S +    THTT  P++T
Sbjct: 918 SHSRPGSTHTTAFPDST 934



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 126/596 (21%), Positives = 216/596 (36%), Gaps = 84/596 (14%)

Query: 298  SAHTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTP 357
            S HT+     S TR  E     S   S+  R   P        T ++A   P  +  G+P
Sbjct: 678  SPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPP--------TTTSAFVEPSTTSHGSP 729

Query: 358  GSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGES----GSQEGGVNS 413
             S+ ++  S+          T S L  +S ++     +T+ +H  ES    G  E    S
Sbjct: 730  SSIPTTHISARS--------TTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS 781

Query: 414  FS----TLIGLPST-SAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKR 468
             S    T+   PST SA+  +P S+ +SPG    +  P +    + TSG  EE++     
Sbjct: 782  HSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS----STTSGRSEESI----- 832

Query: 469  KGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSS----VASAAGSITSSSLQKSPTLLR 524
              +  S+   G         N   L  S+ SP SS      +  GS T+  L +  T   
Sbjct: 833  -ASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFH 891

Query: 525  NG------SLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSF 578
            +       +L   S  SS V  E +  +   G+  TT F +  +    G+   +  + S 
Sbjct: 892  SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPD--STTTPGLSRHSTTSHSS 949

Query: 579  PNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQA 638
            P    GS  +T      LP  ++  L  VG  + S +SS +        +T +     ++
Sbjct: 950  P----GSTDTT-----LLPASTTTXL--VGEPTTSPISSGSTETTALPGSTTTAGLSEKS 998

Query: 639  PSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRY 698
             +     RS  +  +  + + +  +++    +SR      ++  GS +           +
Sbjct: 999  TTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH 1058

Query: 699  DQPGNSSLENLPPVAASIEQLLERQ-------WSEGQQFLLEQGTPSDILGMLKSLHQLQ 751
              PG++    L P + +   L            S     L +  T S +L     +H   
Sbjct: 1059 SSPGSTD-TTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSST 1117

Query: 752  VENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNS 811
               R       + T + E              + T    PS +  T  A    T+  +  
Sbjct: 1118 GSPRTTLSPAGSTTRQGE--------------STTFQSWPSSK-DTMPAPPTTTSAFVEL 1162

Query: 812  SKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGV 867
            S + H   S +P       +   T+ G+S  S++  S+P     +P+   S  SG+
Sbjct: 1163 STTSHGSPSSIPTTH---FSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGL 1215



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 102/483 (21%), Positives = 174/483 (36%), Gaps = 63/483 (13%)

Query: 208  SNRSYDQSLSDSSSHSQDKHHEKEKKKYKEKDKHKQ-----------------KHKKQPE 250
            S RS D +LS +S+ S     E      +    H                    H     
Sbjct: 1004 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 1063

Query: 251  PSPALVPSLTVTTEKTYTSTSNNSISGSLKRL---EDTTARFTNANFQEVSAHTSSGKDV 307
                L P  T  +     ST+ +S  GS +     ++TTA         V + T S +  
Sbjct: 1064 TDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTT 1123

Query: 308  SETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSA---ASPFPQGSFSGTPGSVKSSS 364
                GS  +  +S+   S    +       P TT SA    S    GS S  P +  S+S
Sbjct: 1124 LSPAGSTTRQGESTTFQSWPSSKDTMPA--PPTTTSAFVELSTTSHGSPSSIPTTHFSAS 1181

Query: 365  GSSVQSPQDFLSF----------------TDSDLRNDSYSHSQQSSATKDVHKGESG--- 405
             ++    ++  +                 T S L  +S ++     +T+ +H  ES    
Sbjct: 1182 STTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 1241

Query: 406  --SQEGGVNSFSTLIGLPS----TSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIE 459
              S+E   +  ST   + S    TSA+  +P S+ +SPG +  +  P    + + TSG  
Sbjct: 1242 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP----ESSTTSGRS 1297

Query: 460  EETVKEKKRKGNKQSKHGPGR--PKGNKNQENVSHLSVSSASPT-SSVASAAGSITSSSL 516
            EE+               P      G   +    ++S  S   T +S A+  G    S++
Sbjct: 1298 EESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTI 1357

Query: 517  QKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAV 576
              S +   + +L   S+ SS +  E +  Y    +  TT F    +   +G+   +    
Sbjct: 1358 LYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFP--ASTTTSGLSQESTTFH 1415

Query: 577  SFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLS 636
            S P     + S   +++S   Q+ +    Q G    SA+S+ +PA  T    +   ++  
Sbjct: 1416 SKPGSTETTLSPGSITTSSFAQEFTTPHSQPG----SALSTVSPASTTVPGLSEESTTFY 1471

Query: 637  QAP 639
             +P
Sbjct: 1472 SSP 1474



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 125/643 (19%), Positives = 210/643 (32%), Gaps = 108/643 (16%)

Query: 333 GGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQ 392
           GG     +T S++ PF   +FS    SV   +GS+         F DS   +    HS++
Sbjct: 95  GGNTTSASTPSSSDPFT--TFSDYGVSVTFITGSTATK-----HFLDSSTNS---GHSEE 144

Query: 393 SSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLP------ 446
           S+ +         +     ++ S  +G P TS +TS        PG    + L       
Sbjct: 145 STVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTF 204

Query: 447 ---------TAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPK--GNKNQENVSH--- 492
                    T    R  +SG+ E++     R G   +   P      G   +   SH   
Sbjct: 205 YSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIP 264

Query: 493 ------LSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQY 546
                 LS  + +P+S    +    +S    K+  L  N +   L   S+PV S      
Sbjct: 265 GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGS-- 322

Query: 547 RHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQ 606
                 P TT S   +  H G         S+P+    S + +  +S+ +   ++ H   
Sbjct: 323 ------PHTTLSPASSTTHEG---EPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHS-- 371

Query: 607 VGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQD 666
               SPS+     P    + ++T  G S    P H                         
Sbjct: 372 ----SPSST----PTTHFSASSTTLGHSEESTPVH------------------------- 398

Query: 667 LGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSE 726
               S  +    + P    +    V      +  PG++   + P  + +     E     
Sbjct: 399 ----SSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFH 454

Query: 727 GQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTIT 786
           G     +  TPS    +  + +   + +       ++ +    R +   A  S P    T
Sbjct: 455 GSTTHTKSSTPSTTAALAHTSYHSSLGSTETTH-FRDSSTISGRSEESKASHSSPDAMAT 513

Query: 787 ANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSA 846
                        A + P+    +S+ SP I +  +   +LP      T  G S  S++ 
Sbjct: 514 T---------VLPAGSTPSVLVGDSTPSP-ISSGSMETTALP---GSTTKPGLSEKSTTF 560

Query: 847 LSTP--PPAGQSPAQQ-GSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALP 903
            S+P  P     PA    SGVS     +    G+  +   P ++T+P +S       + P
Sbjct: 561 YSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSP 620

Query: 904 G---NQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNAT 943
           G     L+      +  G   T  T    P     T +P N T
Sbjct: 621 GPTDTTLSPGSTTASSLGPEYT--TFHSRPGSTETTLLPDNTT 661



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 53/243 (21%), Positives = 87/243 (35%), Gaps = 43/243 (17%)

Query: 788 NPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSAL 847
           +P  S  + T +   + TT  L+   +    +   PD +L       TSSG S  S+++ 
Sbjct: 176 SPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPART--TSSGVSEKSTTSH 233

Query: 848 STPPPAGQSPAQQGSGVSGVQQVNGVT---VGALASGMQPVTSTIPAVSAVGGIIGALPG 904
           S P P         + + GV Q +  +    G+  + + P T+T  ++        + PG
Sbjct: 234 SRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPG 293

Query: 905 --------NQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNA-------------- 942
                   +    +G++ A      TPV  S   T   HTT+ P +              
Sbjct: 294 YTKTTRLPDNTTTSGLLEA-----STPVHSS---TGSPHTTLSPASSTTHEGEPTTFQSW 345

Query: 943 -----THPMPATLTNSASGLGLL---SDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQ 994
                T P P+  T++   L      S               L +S++ TPVH  P  T 
Sbjct: 346 PSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA 405

Query: 995 LPP 997
             P
Sbjct: 406 TTP 408


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 163/746 (21%), Positives = 268/746 (35%), Gaps = 133/746 (17%)

Query: 248 QPEPSPALVPSLTVTTEKTYTSTSNNSISG----SLKRLEDTT---ARFTNANFQEVSAH 300
           +P+ SP    S+  T     T+T+  S       S  R  D T   AR T++   E S  
Sbjct: 107 EPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTT 166

Query: 301 TSSGKDVSETRG------SEGKGKKSSAHSSGQRGRKPGGGR---NPGTTVSAASPFPQG 351
           + S    + T          G  ++S+A  S      PG      +PGTT  ++      
Sbjct: 167 SHSRPGPTHTIAFPDSTTMPGVSQESTASHS-----IPGSTDTTLSPGTTTPSSLGPEST 221

Query: 352 SFSGTPGSVKSS--------SG---------SSVQSPQDFLSFTDSDLRNDSYSHSQQSS 394
           +F  +PG  K++        SG         SS  SP   LS + S       +  Q   
Sbjct: 222 TFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWP 281

Query: 395 ATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK--- 451
           ++KD     SG+    V   +T    PS++  T     F  S   LG+S   T  +    
Sbjct: 282 SSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTH----FSASSTTLGHSEESTPVHSSPV 337

Query: 452 ---------RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE-------NVSHLSV 495
                    R+ TSG  EE+    +  G+ Q+ H P     + + E       + +H   
Sbjct: 338 ATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS 397

Query: 496 SSASPTSSVA-----SAAGSITSSSLQKSPTL---------------------LRNGSLQ 529
           S+ S T+++A     S+ GS  ++  + S T+                     L  GS  
Sbjct: 398 STPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP 457

Query: 530 SLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNS--NDVAVSFPNVVSGSGS 587
           S+ VG S   S IS       A P +T    L+      Y+S  +      P  ++ SG 
Sbjct: 458 SVLVGDS-TPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPARMTSSGV 516

Query: 588 STPVSSSHLPQQSS------GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSH 641
           S   ++SH    S+      G     G    S  S ++P    T  +  S ++ S  P +
Sbjct: 517 SEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 576

Query: 642 MYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVS---SLQIRY 698
              + S  S    +    +N T   L + S  +     SP  +LSP    +        +
Sbjct: 577 TTFHSSPGSTETTLL--PDNTTASGLLEASTPVHSSTRSPHTTLSPAGSTTRQGESTTFH 634

Query: 699 DQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLH-QLQVENRRL 757
             P +      PP   S         +  +      G+PS I     + H   +     L
Sbjct: 635 SWPSSKDTRPAPPTTTS---------AFVEPSTTSHGSPSSI----PTTHISARSTTSGL 681

Query: 758 EEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDS--LNSSKSP 815
            E+     +     Q ++   S          + SH   T +  +AP+T S  +    S 
Sbjct: 682 VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 741

Query: 816 H-----IGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQ--SPAQQGSGV-SGV 867
           H        +  PD+S        T+SG+S  S+++ S+    G    PA+  + V  G 
Sbjct: 742 HSSPGSTATTHFPDSS--------TTSGRSEESTASHSSQDATGTIVLPARSTNSVLLGE 793

Query: 868 QQVNGVTVGALASGMQPVTSTIPAVS 893
              + ++ G++ +   P ++T P +S
Sbjct: 794 STTSPISSGSMETTALPGSTTTPGLS 819



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 104/456 (22%), Positives = 167/456 (36%), Gaps = 90/456 (19%)

Query: 251 PSPALVPSLTVT-----TEKTYTSTSNNSISGSLKRLEDTT---ARFTNANFQEVSAHTS 302
           PSP    S+  T     T K   S  + +   S  R  DTT   AR T++   E S  + 
Sbjct: 466 PSPISSGSMETTALPGSTTKPGLSEKSTTFYSS-PRSPDTTHLPARMTSSGVSEESTTSH 524

Query: 303 SGKDVSETRGSEGK----GKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPG 358
           S    + T    G     G    + +S           +PG+T +++      +F  +PG
Sbjct: 525 SRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSSPG 584

Query: 359 SVKSSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLI 418
           S +++      +    L  +     +    H+  S A     +GES +     +S  T  
Sbjct: 585 STETTLLPDNTTASGLLEASTPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 644

Query: 419 GLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK-RAQTSGIEEETVKEKKRKGNKQSKHG 477
             P+T++   +P +  +       SS+PT     R+ TSG+ EE+       G+ Q+ H 
Sbjct: 645 APPTTTSAFVEPSTTSHG----SPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHF 700

Query: 478 PGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSP 537
           P     +   E     S +S S T+   S+A S T+S+L + PT          S  SSP
Sbjct: 701 PESDTTSGRGEE----STTSHSSTTHTISSAPS-TTSALVEEPT----------SYHSSP 745

Query: 538 VGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLP 597
                       G+  TT                      FP+  + SG S   ++SH  
Sbjct: 746 ------------GSTATT---------------------HFPDSSTTSGRSEESTASHSS 772

Query: 598 QQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQ 657
           Q ++G +               PA +T   + L G S +   S   G+   +++      
Sbjct: 773 QDATGTI-------------VLPARSTN--SVLLGESTTSPISS--GSMETTAL------ 809

Query: 658 SENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSS 693
              + T   L + S        SP  +LSP S  SS
Sbjct: 810 -PGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSS 844



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 76/320 (23%), Positives = 124/320 (38%), Gaps = 43/320 (13%)

Query: 252 SPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETR 311
           SP    + ++  E T   +S  S   +L     T +    A+    S+  S    +S   
Sbjct: 563 SPGSTTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTRSPHTTLSPAG 622

Query: 312 GSEGKGKKSSAHS-SGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQS 370
            +  +G+ ++ HS    +  +P     P TT SA    P  +  G+P S+ ++  S+   
Sbjct: 623 STTRQGESTTFHSWPSSKDTRPA----PPTTTSAFVE-PSTTSHGSPSSIPTTHISARS- 676

Query: 371 PQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGES----GSQEGGVNSFS----TLIGLPS 422
                  T S L  +S ++     +T+ +H  ES    G  E    S S    T+   PS
Sbjct: 677 -------TTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPS 729

Query: 423 T-SAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRP 481
           T SA+  +P S+ +SPG    +  P +    + TSG  EE+        +  S+   G  
Sbjct: 730 TTSALVEEPTSYHSSPGSTATTHFPDS----STTSGRSEEST------ASHSSQDATGTI 779

Query: 482 KGNKNQENVSHLSVSSASPTSS----VASAAGSITSSSLQKSPTLLRNG------SLQSL 531
                  N   L  S+ SP SS      +  GS T+  L +  T   +       +L   
Sbjct: 780 VLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA 839

Query: 532 SVGSSPVGSEISMQYRHDGA 551
           S  SS V  E +  +   G+
Sbjct: 840 STTSSGVSEESTTSHSRPGS 859



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 79/371 (21%), Positives = 126/371 (33%), Gaps = 64/371 (17%)

Query: 315 GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDF 374
           G G      SS       GG     +T S++ PF   +FS    SV   +GS+       
Sbjct: 12  GAGAFVDDRSSSTVNTSIGGNTTSASTPSSSDPFT--TFSDYGVSVTFITGSTATK---- 65

Query: 375 LSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFE 434
             F DS   +    HS++S+ +         +     ++ S  +G P TS +TS      
Sbjct: 66  -HFLDSSTNS---GHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETT 121

Query: 435 NSPGDLGNSSLP---------------TAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPG 479
             PG    + L                T    R  +SG+ E++     R G   +   P 
Sbjct: 122 ALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPD 181

Query: 480 RP--KGNKNQENVSH---------LSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSL 528
                G   +   SH         LS  + +P+S    +    +S    K+  L  N + 
Sbjct: 182 STTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTT 241

Query: 529 QSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNG-------IYNSNDVA------ 575
             L   S+PV S            P TT S   +  H G         +S D +      
Sbjct: 242 SGLLEASTPVHSST--------GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGT 293

Query: 576 ----VSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAA---PAVATTQAN 628
               V        S SSTP +       + GH ++   +  S V++A    PA + T  +
Sbjct: 294 TSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGH 353

Query: 629 TLSGSSLSQAP 639
               ++  ++P
Sbjct: 354 VEESTAYHRSP 364



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 53/243 (21%), Positives = 88/243 (36%), Gaps = 43/243 (17%)

Query: 788 NPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSAL 847
           +P  S  + T +   + TT  L+   +    +   PD +L       TSSG S  S+++ 
Sbjct: 111 SPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPART--TSSGVSEKSTTSH 168

Query: 848 STPPPAGQSPAQQGSGVSGVQQVNGVT---VGALASGMQPVTSTIPAVSAVGGIIGALPG 904
           S P P         + + GV Q +  +    G+  + + P T+T  ++        + PG
Sbjct: 169 SRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPG 228

Query: 905 --------NQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNA-------------- 942
                   +    +G++ A      TPV  S   T   HTT+ P++              
Sbjct: 229 YTKTTRLPDNTTTSGLLEA-----STPVHSS---TGSPHTTLSPSSSTTHEGEPTTFQSW 280

Query: 943 -----THPMPATLTNSASGLGLL---SDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQ 994
                T P P+  T++   L      S               L +S++ TPVH  P  T 
Sbjct: 281 PSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA 340

Query: 995 LPP 997
             P
Sbjct: 341 TTP 343



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 38/172 (22%), Positives = 65/172 (37%), Gaps = 14/172 (8%)

Query: 782 FPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSF---LPDNSLPVLNQDLTSSG 838
           FP  +     S +  TF   T  T  S  S+ +     S+   L            T SG
Sbjct: 372 FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG 431

Query: 839 QSTSSSSALSTPP-------PAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPA 891
           +S  S ++ S+P        PAG +P    S + G    + ++ G++ +   P ++T P 
Sbjct: 432 RSEESKASHSSPDAMATTVLPAGSTP----SVLVGDSTPSPISSGSMETTALPGSTTKPG 487

Query: 892 VSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNAT 943
           +S       + P +    +      +  +    T S +    THTT  P +T
Sbjct: 488 LSEKSTTFYSSPRSPDTTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGST 539


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 133/756 (17%), Positives = 266/756 (35%), Gaps = 80/756 (10%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE--- 314
            S T +   T ++TS+ + + S +  E TT   T++    VS  T S + ++ T GSE   
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST-TGSERTITSTEGSETTT 675

Query: 315  -------------GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
                         G G  + + +  +  +    G    TT +  S     S +G+  +  
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 362  SSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLP 421
            S+ GS   +     S   S+  + S + S+ ++A+    +    S  G   + ++ IG  
Sbjct: 736  STEGSETTT----ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 422  STSAVTSQPKS----FENSPGDLGN------SSLPTAGYKRAQTSGIEEETVKEKKRKGN 471
            +T   T+  K      ENS   + +      +++ TAG +    S    ET      +G+
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 472  KQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSL 531
            + +           + E     + S+ S  ++ A+  GS T+++  +        +  S 
Sbjct: 852  ETT---------TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE 902

Query: 532  SVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSGSSTP 590
            +  +S  GSEI+          +TT SE   A   G   +      S    VS +GS T 
Sbjct: 903  TTTASTEGSEIT--------TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954

Query: 591  VSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSS 650
              S+   + ++         + S   S    V+T  + T + +S+  + +    +  + +
Sbjct: 955  TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTT-ASIEGSETTTVSSTGSET 1013

Query: 651  MAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLE 707
                   +E   T  + G  +  +   GS      +  S  ++      +      +  E
Sbjct: 1014 TTVSTTGTETTITSTE-GSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE 1072

Query: 708  NLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAK 767
                  A +E         G       G+ +  + +  S              +   +++
Sbjct: 1073 TTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSE 1132

Query: 768  KERLQLLNAQLSVPFPTI----TANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP 823
                    ++++  F T+    T +   S    + +A +  TT S   S++     +   
Sbjct: 1133 TTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSE 1192

Query: 824  DNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQ 883
              +      + T++  S S ++   T      +P+  GS  +    +   T  A  + ++
Sbjct: 1193 TTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLE 1252

Query: 884  P----------VTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPV----TMSQN 929
            P           T +I A  A            +       ++  +  TP+    T    
Sbjct: 1253 PTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTR 1312

Query: 930  PTPLTHTTVPPN-------ATHPMPATLTNSASGLG 958
            PT  +  T+ P        A+H +P  + N+ SGLG
Sbjct: 1313 PTASSSVTMAPGMDFTASAASHTVPGIVLNT-SGLG 1347



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 80/413 (19%), Positives = 158/413 (38%), Gaps = 16/413 (3%)

Query: 252  SPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETR 311
            S +   S T T   T + T+  SI GS   +  T    T       S  T+   + SET 
Sbjct: 754  SASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETT 813

Query: 312  GSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSP 371
             +     +++  S+      P       TT + ++   + + + T GS ++++ S+  S 
Sbjct: 814  IASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS-ETTTASTESSE 872

Query: 372  QDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPK 431
                +   S+    S   S+ ++ + +  +  + S EG   S  T +    +   T+  +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG---SEITTVSTTGSETTTASTE 929

Query: 432  SFENSPGDLGNSSLPTAGYKRAQT-----SGIEEETVKEKKRKGNKQSKHGPGRPKGNKN 486
              E +      S L T     ++T      G E  TV     +    S  G      +  
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 487  QENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQY 546
                +  S+  +  T+  ++ + + T S+     T+      ++ +V ++  GSE +  Y
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTA--GSETTAVY 1047

Query: 547  RHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNV----VSGSGSSTPVSSSHLPQQSSG 602
               G+  TTT +E           S     S  ++    VS SGS T  +S+   + ++ 
Sbjct: 1048 T-TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 603  HLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALI 655
            ++      + S   S A  V+TT + T + S+     + ++   S ++  + I
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTI 1159



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 118/646 (18%), Positives = 221/646 (34%), Gaps = 53/646 (8%)

Query: 260  TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
            T  +E T  ST+++  + +     +TT+  T  +    ++ TSS    + T GSE     
Sbjct: 588  TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 315  -GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQD 373
                + +   ++G          +  TTVSA       S  G+  +  S +GS       
Sbjct: 648  TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTK--- 704

Query: 374  FLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSF 433
             +S T S+    S   S+ ++A+    +  + S EG   + ++  G  +TSA T+  ++ 
Sbjct: 705  -VSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETT 763

Query: 434  ENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
              S      +     G +    S I  ET K         +          +N E    +
Sbjct: 764  TASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF-------TENSETT--I 814

Query: 494  SVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP 553
            + ++AS T++V++A      +S   S T     +  S +  +S  GSE +          
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 554  TTTF--SELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALS 611
            T T   SE   A   G         S     S  GS T  +S+         +  V    
Sbjct: 875  TATTIGSETTTASTEG---------SETTTTSTEGSETTTAST-----EGSEITTVSTTG 920

Query: 612  PSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNS 671
                +++     TT A+T  GS L+        + + S    + A+     T   +G  +
Sbjct: 921  SETTTASTEGSETTTAST-EGSELTTV------STTGSETITVSAEGSETTTVTTMGSET 973

Query: 672  RNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLENLPPVAASIEQLLERQWSEGQ 728
                  GS      +  S  ++  I   +     ++  E         E  +    +EG 
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS--TEGS 1031

Query: 729  QFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVP------F 782
            +        S+   +  +  +    +    E     T   E      A L          
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 783  PTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTS 842
             T TA+ + S     +   +  TT S   S++  +  +     +      ++T+   + S
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 843  SSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
             ++ +ST      + +  GS  +        T  A  +G +  T++
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 118/672 (17%), Positives = 235/672 (34%), Gaps = 71/672 (10%)

Query: 263  TEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE-------G 315
            +E T T T  + ++     + +TT   T  +   +++ + S    + T GSE       G
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 316  KGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ------ 369
               K++  +  +       G    T  +  S     S  G+  +  S++GS +       
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 370  ----------SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIG 419
                      S    +S T  +    S   S+ ++ +    +  + S EG   + ++  G
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 420  LPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK------------RAQTSGIEEETVKEKK 467
              +T+  T+  ++   S  D   +S  T G +             A T G E  TV    
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 468  RKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGS 527
             +    S  G  R     + E     +VS+    ++V++     T+ S+  S T  +  +
Sbjct: 651  SETTMVSTTGSERT--ITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSET-TKVST 707

Query: 528  LQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSG 586
              S +  +S  GSEI+          + T SE   A   G   +      S     S +G
Sbjct: 708  TGSETTTTSTEGSEIT--------TASITGSETTTASTEGSETTTASTEGSETTSASTTG 759

Query: 587  SSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVAT---------TQANTLSGSSLSQ 637
            S T  +S+   + +   +        S + S    V+T         T+ +  + +S + 
Sbjct: 760  SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 819

Query: 638  APSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIR 697
            + +       + ++ A  A SE   T    G  +      GS    + +  S  ++    
Sbjct: 820  SETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI 879

Query: 698  YDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRL 757
              +   +S E       S         +EG +        S+I  +  +  +    +   
Sbjct: 880  GSETTTASTEGSETTTTS---------TEGSETTTASTEGSEITTVSTTGSETTTAS--- 927

Query: 758  EEQIKNLTAKKERLQLLNAQLS-VPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPH 816
             E  +  TA  E  +L     +     T++A  S +  + T  ++T  TT S   S++  
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSET--TTASTAGSETTT 985

Query: 817  IGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVG 876
            +  +     +  +   + T+   + S ++ +ST        + +GS  + V      T  
Sbjct: 986  VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTA 1045

Query: 877  ALASGMQPVTST 888
               +G +  T++
Sbjct: 1046 VYTTGSETTTTS 1057



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 94/422 (22%), Positives = 159/422 (37%), Gaps = 70/422 (16%)

Query: 250 EPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSE 309
           E + +   S T T   T T T+  S  GS      TT+  T       S  T+     SE
Sbjct: 94  ETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE 153

Query: 310 TRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ 369
           T  +     +++A S+         G    T  +A S     S +G+  +  S++GS   
Sbjct: 154 TTTAYTADSETTAAST--------TGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205

Query: 370 SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQ 429
           +    +S T S+    S +HS+ ++A+    +    S  G   + ST  G  +T+A T  
Sbjct: 206 T----VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST-AGSETTAASTED 260

Query: 430 PKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQ 487
            ++      D   ++  T G++   A T+G E         +    S  GP   K     
Sbjct: 261 SETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK----- 315

Query: 488 ENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYR 547
                  VS+AS   +   AAGS T                    + +S VGSE +    
Sbjct: 316 -------VSTASSEVTTVFAAGSET--------------------IRASTVGSETT---- 344

Query: 548 HDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQV 607
                 +TT SE   A   G   S D         S +GS T  +S+   + ++   +  
Sbjct: 345 ----TVSTTGSETTTASIMGSETSTD---------STTGSETTTASTEGSETTTASTEGS 391

Query: 608 GALSPSAVSSAAPAVATTQANTLS----GSSLSQAPSHMYGNRSNSSMAA--LIAQSENN 661
            A + S   S    V+ T + T +    GS ++   + ++   + S+  +   IA + ++
Sbjct: 392 EATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDS 451

Query: 662 QT 663
           +T
Sbjct: 452 ET 453



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 77/351 (21%), Positives = 136/351 (38%), Gaps = 20/351 (5%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKG 317
            S T T   T T T+  S  GS      T    T A +   S  T++  + SET      G
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 318  KKSSAHSSGQRGRKPGGGRNPGTTV--SAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFL 375
             +++  S+             GTT   +A S       +G+  +  S+ GS   +    +
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATT----V 1126

Query: 376  SFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFEN 435
            S T S+    S + S+ ++    V +  + S  G   + S+  G  +T+  T   ++   
Sbjct: 1127 STTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTA 1186

Query: 436  SPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
            S      ++  TAG +   A TSG E  T      + +  S  G             +  
Sbjct: 1187 STAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIA 1246

Query: 494  SVSSASPTSSVASAAG----SITSSSLQKSPTLLRNGSL---QSLSVGSSPVGSEISMQY 546
            S +S  PT++  + +     SIT+S    + T + + +    ++  V   P+ +      
Sbjct: 1247 STASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGT 1306

Query: 547  RHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVV---SGSGSSTPVSSS 594
            R  G  PT + S  +       + ++  + + P +V   SG G+ST  +SS
Sbjct: 1307 RTTGTRPTASSS--VTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASS 1355



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 108/653 (16%), Positives = 229/653 (35%), Gaps = 47/653 (7%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKK 319
           T+  E T  ST+++ ++       +T    T  +  E +  +++G   SET  +   G +
Sbjct: 308 TIGPETTKVSTASSEVTTVFAAGSETIRASTVGS--ETTTVSTTG---SETTTASIMGSE 362

Query: 320 SSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTD 379
           +S  S+         G    T  +  S     S  G+  +  S++GS   +    +S TD
Sbjct: 363 TSTDSTT--------GSETTTASTEGSETTTASTEGSEATTVSTTGSETTT----VSITD 410

Query: 380 SDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGD 439
           S+        S+ ++ +  V +  + S EG   + ++     +T+A T   ++   +   
Sbjct: 411 SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 440 LGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSS 497
               +  T G +   A  +G+E  TV          S  G      +     ++ +S   
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 498 ASPT--SSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTT 555
           +  T  S+  S   +++++ L+ + T      + ++S   +   ++ S +     A  T 
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD-STEGSGTTAASTA 589

Query: 556 TFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAV 615
                  +  +    +   A S     S +GS T  +S+   + ++   +     + S  
Sbjct: 590 GSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTT 649

Query: 616 SSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLV 675
            S    V+TT +     S+     + +    S ++++    +     T    G  +  + 
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSITGSETTKVS 706

Query: 676 GRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWS-EGQQFLLEQ 734
             GS    + +  S +++  I   +   +S E      AS E       S  G +     
Sbjct: 707 TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 735 GTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQ 794
            T S+         +  + +    E  K  TA  +   +          + TA  S +  
Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA--SETTT 824

Query: 795 IHTFSAQTAP-------------------TTDSLNSSKSPHIGNSFLPDNSLPVLNQDLT 835
           + T  ++T P                   TT S   S++           +   +  + T
Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 836 SSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
           ++    S ++  ST      + + +GS ++ V      T  A   G +  T++
Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 89/422 (21%), Positives = 156/422 (36%), Gaps = 25/422 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARF----TNANFQEVSAHTSSGKDVSETRGSEG 315
           T+ +E T  ST+ +  + S    E T A      TN  F E S  T++     ET  +  
Sbjct: 229 TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 316 KGKKSSAHSSGQRGRKPGGGRNPGTT-VSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDF 374
            G + +  S+            P TT VS AS      F+    ++++   S+V S    
Sbjct: 289 TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA---STVGSETTT 345

Query: 375 LSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFE 434
           +S T S+    S   S+ S+ +    +  + S EG   + ++  G  +T+  T+  ++  
Sbjct: 346 VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405

Query: 435 NSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLS 494
            S  D   ++  T G +    S    ET                       + E     +
Sbjct: 406 VSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTT 465

Query: 495 VSSASPTSSVASAAGSITSSSLQ---KSPTLLRNGS-------LQSLSVGSSPVGSEISM 544
           V++A   +  A   GS T+++     ++ T+   GS         S +   S  GSE++ 
Sbjct: 466 VTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTT 525

Query: 545 QYRH--DGACPTTTFSELLNAIHNGI-YNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSS 601
                 +    +TT SE       G+   +     S    VS +G+ T   S+    + S
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST----EGS 581

Query: 602 GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENN 661
           G      A S +   S A +  TT +   S ++ +          S +S     A +E +
Sbjct: 582 GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS 641

Query: 662 QT 663
           +T
Sbjct: 642 ET 643



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 85/470 (18%), Positives = 165/470 (35%), Gaps = 25/470 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
           T ++E T TST+ +  +       +TT  +T  +    ++ T S      T GSE     
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 315 --GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSG-----SS 367
             G    + + +  +       G    T  +A S     S  G+  +  S++G     S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 368 VQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVT 427
             S     S  DS+        S+ ++A+    +  + S  G   + ++ +G  +T A T
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 428 SQPKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNK 485
             P++ + S      +++  AG +  RA T G E  TV     +    S  G      + 
Sbjct: 309 IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 486 NQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQ 545
                +  S   +  T++    + + T S+     T +      S +  +   GSE++  
Sbjct: 369 TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV--SITDSETTTTCTEGSEMT-- 424

Query: 546 YRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                A  TT F     +           + S     S  GS T   ++   +  + +  
Sbjct: 425 -----AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTT 479

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQ 665
                + S        V T  ++T + S+     + +  + + S M  +  +   N T  
Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV--SATGSEMTTVSTEGSENTTVS 537

Query: 666 DLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAAS 715
             G  +  +   G     + +  S ++++     +    S E     AAS
Sbjct: 538 TTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 79/389 (20%), Positives = 143/389 (36%), Gaps = 24/389 (6%)

Query: 258 SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFT---NANFQEVSAHTSSGKDVSE--TRG 312
           S T+T     + T+  S +GS      TT   T   +    E +A ++ G + ++  T G
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 313 SE----GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSV 368
           SE      G +++A S+           +  TT ++ + F + + + T GS + +  S++
Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF-ETTAASTTGS-EPTMASTM 299

Query: 369 QSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTS 428
            S     S    +    S   +  S  T     G    +   V S +T +    +   T+
Sbjct: 300 GSETTMASTIGPETTKVS---TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 429 QPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE 488
                E S      S   T     A T G E  T   +  +    S  G      +    
Sbjct: 357 SIMGSETSTDSTTGSETTT-----ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 489 NVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRH 548
             +  + +  S  ++V++     T++S + S   + + S  S +  +S  GSE +     
Sbjct: 412 ETT-TTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS-DSETTTASTEGSETTTVTTA 469

Query: 549 DGACPT--TTFSELLNAIHNGIYNSNDVAV-SFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                T  TT SE   A + G+  +    + S     S  GS T   S+   + ++   +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTE 529

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSS 634
                + S   S    V+TT   T + S+
Sbjct: 530 GSENTTVSTTGSETTTVSTTGLETTTTST 558


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 133/756 (17%), Positives = 266/756 (35%), Gaps = 80/756 (10%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE--- 314
            S T +   T ++TS+ + + S +  E TT   T++    VS  T S + ++ T GSE   
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST-TGSERTITSTEGSETTT 675

Query: 315  -------------GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
                         G G  + + +  +  +    G    TT +  S     S +G+  +  
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 362  SSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLP 421
            S+ GS   +     S   S+  + S + S+ ++A+    +    S  G   + ++ IG  
Sbjct: 736  STEGSETTT----ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 422  STSAVTSQPKS----FENSPGDLGN------SSLPTAGYKRAQTSGIEEETVKEKKRKGN 471
            +T   T+  K      ENS   + +      +++ TAG +    S    ET      +G+
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 472  KQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSL 531
            + +           + E     + S+ S  ++ A+  GS T+++  +        +  S 
Sbjct: 852  ETT---------TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE 902

Query: 532  SVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSGSSTP 590
            +  +S  GSEI+          +TT SE   A   G   +      S    VS +GS T 
Sbjct: 903  TTTASTEGSEIT--------TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954

Query: 591  VSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSS 650
              S+   + ++         + S   S    V+T  + T + +S+  + +    +  + +
Sbjct: 955  TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTT-ASIEGSETTTVSSTGSET 1013

Query: 651  MAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLE 707
                   +E   T  + G  +  +   GS      +  S  ++      +      +  E
Sbjct: 1014 TTVSTTGTETTITSTE-GSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE 1072

Query: 708  NLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAK 767
                  A +E         G       G+ +  + +  S              +   +++
Sbjct: 1073 TTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSE 1132

Query: 768  KERLQLLNAQLSVPFPTI----TANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP 823
                    ++++  F T+    T +   S    + +A +  TT S   S++     +   
Sbjct: 1133 TTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSE 1192

Query: 824  DNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQ 883
              +      + T++  S S ++   T      +P+  GS  +    +   T  A  + ++
Sbjct: 1193 TTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLE 1252

Query: 884  P----------VTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPV----TMSQN 929
            P           T +I A  A            +       ++  +  TP+    T    
Sbjct: 1253 PTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTR 1312

Query: 930  PTPLTHTTVPPN-------ATHPMPATLTNSASGLG 958
            PT  +  T+ P        A+H +P  + N+ SGLG
Sbjct: 1313 PTASSSVTMAPGMDFTASAASHTVPGIVLNT-SGLG 1347



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 80/413 (19%), Positives = 158/413 (38%), Gaps = 16/413 (3%)

Query: 252  SPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETR 311
            S +   S T T   T + T+  SI GS   +  T    T       S  T+   + SET 
Sbjct: 754  SASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETT 813

Query: 312  GSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSP 371
             +     +++  S+      P       TT + ++   + + + T GS ++++ S+  S 
Sbjct: 814  IASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS-ETTTASTESSE 872

Query: 372  QDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPK 431
                +   S+    S   S+ ++ + +  +  + S EG   S  T +    +   T+  +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG---SEITTVSTTGSETTTASTE 929

Query: 432  SFENSPGDLGNSSLPTAGYKRAQT-----SGIEEETVKEKKRKGNKQSKHGPGRPKGNKN 486
              E +      S L T     ++T      G E  TV     +    S  G      +  
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 487  QENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQY 546
                +  S+  +  T+  ++ + + T S+     T+      ++ +V ++  GSE +  Y
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTA--GSETTAVY 1047

Query: 547  RHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNV----VSGSGSSTPVSSSHLPQQSSG 602
               G+  TTT +E           S     S  ++    VS SGS T  +S+   + ++ 
Sbjct: 1048 T-TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 603  HLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALI 655
            ++      + S   S A  V+TT + T + S+     + ++   S ++  + I
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTI 1159



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 118/646 (18%), Positives = 221/646 (34%), Gaps = 53/646 (8%)

Query: 260  TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
            T  +E T  ST+++  + +     +TT+  T  +    ++ TSS    + T GSE     
Sbjct: 588  TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 315  -GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQD 373
                + +   ++G          +  TTVSA       S  G+  +  S +GS       
Sbjct: 648  TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTK--- 704

Query: 374  FLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSF 433
             +S T S+    S   S+ ++A+    +  + S EG   + ++  G  +TSA T+  ++ 
Sbjct: 705  -VSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETT 763

Query: 434  ENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
              S      +     G +    S I  ET K         +          +N E    +
Sbjct: 764  TASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF-------TENSETT--I 814

Query: 494  SVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP 553
            + ++AS T++V++A      +S   S T     +  S +  +S  GSE +          
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 554  TTTF--SELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALS 611
            T T   SE   A   G         S     S  GS T  +S+         +  V    
Sbjct: 875  TATTIGSETTTASTEG---------SETTTTSTEGSETTTAST-----EGSEITTVSTTG 920

Query: 612  PSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNS 671
                +++     TT A+T  GS L+        + + S    + A+     T   +G  +
Sbjct: 921  SETTTASTEGSETTTAST-EGSELTTV------STTGSETITVSAEGSETTTVTTMGSET 973

Query: 672  RNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLENLPPVAASIEQLLERQWSEGQ 728
                  GS      +  S  ++  I   +     ++  E         E  +    +EG 
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS--TEGS 1031

Query: 729  QFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVP------F 782
            +        S+   +  +  +    +    E     T   E      A L          
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 783  PTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTS 842
             T TA+ + S     +   +  TT S   S++  +  +     +      ++T+   + S
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 843  SSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
             ++ +ST      + +  GS  +        T  A  +G +  T++
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 118/672 (17%), Positives = 235/672 (34%), Gaps = 71/672 (10%)

Query: 263  TEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE-------G 315
            +E T T T  + ++     + +TT   T  +   +++ + S    + T GSE       G
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 316  KGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ------ 369
               K++  +  +       G    T  +  S     S  G+  +  S++GS +       
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 370  ----------SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIG 419
                      S    +S T  +    S   S+ ++ +    +  + S EG   + ++  G
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 420  LPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK------------RAQTSGIEEETVKEKK 467
              +T+  T+  ++   S  D   +S  T G +             A T G E  TV    
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 468  RKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGS 527
             +    S  G  R     + E     +VS+    ++V++     T+ S+  S T  +  +
Sbjct: 651  SETTMVSTTGSERT--ITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSET-TKVST 707

Query: 528  LQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSG 586
              S +  +S  GSEI+          + T SE   A   G   +      S     S +G
Sbjct: 708  TGSETTTTSTEGSEIT--------TASITGSETTTASTEGSETTTASTEGSETTSASTTG 759

Query: 587  SSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVAT---------TQANTLSGSSLSQ 637
            S T  +S+   + +   +        S + S    V+T         T+ +  + +S + 
Sbjct: 760  SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 819

Query: 638  APSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIR 697
            + +       + ++ A  A SE   T    G  +      GS    + +  S  ++    
Sbjct: 820  SETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI 879

Query: 698  YDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRL 757
              +   +S E       S         +EG +        S+I  +  +  +    +   
Sbjct: 880  GSETTTASTEGSETTTTS---------TEGSETTTASTEGSEITTVSTTGSETTTAS--- 927

Query: 758  EEQIKNLTAKKERLQLLNAQLS-VPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPH 816
             E  +  TA  E  +L     +     T++A  S +  + T  ++T  TT S   S++  
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSET--TTASTAGSETTT 985

Query: 817  IGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVG 876
            +  +     +  +   + T+   + S ++ +ST        + +GS  + V      T  
Sbjct: 986  VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTA 1045

Query: 877  ALASGMQPVTST 888
               +G +  T++
Sbjct: 1046 VYTTGSETTTTS 1057



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 94/422 (22%), Positives = 159/422 (37%), Gaps = 70/422 (16%)

Query: 250 EPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSE 309
           E + +   S T T   T T T+  S  GS      TT+  T       S  T+     SE
Sbjct: 94  ETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE 153

Query: 310 TRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ 369
           T  +     +++A S+         G    T  +A S     S +G+  +  S++GS   
Sbjct: 154 TTTAYTADSETTAAST--------TGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205

Query: 370 SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQ 429
           +    +S T S+    S +HS+ ++A+    +    S  G   + ST  G  +T+A T  
Sbjct: 206 T----VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST-AGSETTAASTED 260

Query: 430 PKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQ 487
            ++      D   ++  T G++   A T+G E         +    S  GP   K     
Sbjct: 261 SETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK----- 315

Query: 488 ENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYR 547
                  VS+AS   +   AAGS T                    + +S VGSE +    
Sbjct: 316 -------VSTASSEVTTVFAAGSET--------------------IRASTVGSETT---- 344

Query: 548 HDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQV 607
                 +TT SE   A   G   S D         S +GS T  +S+   + ++   +  
Sbjct: 345 ----TVSTTGSETTTASIMGSETSTD---------STTGSETTTASTEGSETTTASTEGS 391

Query: 608 GALSPSAVSSAAPAVATTQANTLS----GSSLSQAPSHMYGNRSNSSMAA--LIAQSENN 661
            A + S   S    V+ T + T +    GS ++   + ++   + S+  +   IA + ++
Sbjct: 392 EATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDS 451

Query: 662 QT 663
           +T
Sbjct: 452 ET 453



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 77/351 (21%), Positives = 136/351 (38%), Gaps = 20/351 (5%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKG 317
            S T T   T T T+  S  GS      T    T A +   S  T++  + SET      G
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 318  KKSSAHSSGQRGRKPGGGRNPGTTV--SAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFL 375
             +++  S+             GTT   +A S       +G+  +  S+ GS   +    +
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATT----V 1126

Query: 376  SFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFEN 435
            S T S+    S + S+ ++    V +  + S  G   + S+  G  +T+  T   ++   
Sbjct: 1127 STTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTA 1186

Query: 436  SPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
            S      ++  TAG +   A TSG E  T      + +  S  G             +  
Sbjct: 1187 STAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIA 1246

Query: 494  SVSSASPTSSVASAAG----SITSSSLQKSPTLLRNGSL---QSLSVGSSPVGSEISMQY 546
            S +S  PT++  + +     SIT+S    + T + + +    ++  V   P+ +      
Sbjct: 1247 STASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGT 1306

Query: 547  RHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVV---SGSGSSTPVSSS 594
            R  G  PT + S  +       + ++  + + P +V   SG G+ST  +SS
Sbjct: 1307 RTTGTRPTASSS--VTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASS 1355



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 108/653 (16%), Positives = 229/653 (35%), Gaps = 47/653 (7%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKK 319
           T+  E T  ST+++ ++       +T    T  +  E +  +++G   SET  +   G +
Sbjct: 308 TIGPETTKVSTASSEVTTVFAAGSETIRASTVGS--ETTTVSTTG---SETTTASIMGSE 362

Query: 320 SSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTD 379
           +S  S+         G    T  +  S     S  G+  +  S++GS   +    +S TD
Sbjct: 363 TSTDSTT--------GSETTTASTEGSETTTASTEGSEATTVSTTGSETTT----VSITD 410

Query: 380 SDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGD 439
           S+        S+ ++ +  V +  + S EG   + ++     +T+A T   ++   +   
Sbjct: 411 SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 440 LGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSS 497
               +  T G +   A  +G+E  TV          S  G      +     ++ +S   
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 498 ASPT--SSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTT 555
           +  T  S+  S   +++++ L+ + T      + ++S   +   ++ S +     A  T 
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD-STEGSGTTAASTA 589

Query: 556 TFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAV 615
                  +  +    +   A S     S +GS T  +S+   + ++   +     + S  
Sbjct: 590 GSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTT 649

Query: 616 SSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLV 675
            S    V+TT +     S+     + +    S ++++    +     T    G  +  + 
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSITGSETTKVS 706

Query: 676 GRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWS-EGQQFLLEQ 734
             GS    + +  S +++  I   +   +S E      AS E       S  G +     
Sbjct: 707 TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 735 GTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQ 794
            T S+         +  + +    E  K  TA  +   +          + TA  S +  
Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA--SETTT 824

Query: 795 IHTFSAQTAP-------------------TTDSLNSSKSPHIGNSFLPDNSLPVLNQDLT 835
           + T  ++T P                   TT S   S++           +   +  + T
Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 836 SSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
           ++    S ++  ST      + + +GS ++ V      T  A   G +  T++
Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 89/422 (21%), Positives = 156/422 (36%), Gaps = 25/422 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARF----TNANFQEVSAHTSSGKDVSETRGSEG 315
           T+ +E T  ST+ +  + S    E T A      TN  F E S  T++     ET  +  
Sbjct: 229 TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 316 KGKKSSAHSSGQRGRKPGGGRNPGTT-VSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDF 374
            G + +  S+            P TT VS AS      F+    ++++   S+V S    
Sbjct: 289 TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA---STVGSETTT 345

Query: 375 LSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFE 434
           +S T S+    S   S+ S+ +    +  + S EG   + ++  G  +T+  T+  ++  
Sbjct: 346 VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405

Query: 435 NSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLS 494
            S  D   ++  T G +    S    ET                       + E     +
Sbjct: 406 VSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTT 465

Query: 495 VSSASPTSSVASAAGSITSSSLQ---KSPTLLRNGS-------LQSLSVGSSPVGSEISM 544
           V++A   +  A   GS T+++     ++ T+   GS         S +   S  GSE++ 
Sbjct: 466 VTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTT 525

Query: 545 QYRH--DGACPTTTFSELLNAIHNGI-YNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSS 601
                 +    +TT SE       G+   +     S    VS +G+ T   S+    + S
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST----EGS 581

Query: 602 GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENN 661
           G      A S +   S A +  TT +   S ++ +          S +S     A +E +
Sbjct: 582 GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS 641

Query: 662 QT 663
           +T
Sbjct: 642 ET 643



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 85/470 (18%), Positives = 165/470 (35%), Gaps = 25/470 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
           T ++E T TST+ +  +       +TT  +T  +    ++ T S      T GSE     
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 315 --GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSG-----SS 367
             G    + + +  +       G    T  +A S     S  G+  +  S++G     S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 368 VQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVT 427
             S     S  DS+        S+ ++A+    +  + S  G   + ++ +G  +T A T
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 428 SQPKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNK 485
             P++ + S      +++  AG +  RA T G E  TV     +    S  G      + 
Sbjct: 309 IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 486 NQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQ 545
                +  S   +  T++    + + T S+     T +      S +  +   GSE++  
Sbjct: 369 TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV--SITDSETTTTCTEGSEMT-- 424

Query: 546 YRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                A  TT F     +           + S     S  GS T   ++   +  + +  
Sbjct: 425 -----AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTT 479

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQ 665
                + S        V T  ++T + S+     + +  + + S M  +  +   N T  
Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV--SATGSEMTTVSTEGSENTTVS 537

Query: 666 DLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAAS 715
             G  +  +   G     + +  S ++++     +    S E     AAS
Sbjct: 538 TTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 79/389 (20%), Positives = 143/389 (36%), Gaps = 24/389 (6%)

Query: 258 SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFT---NANFQEVSAHTSSGKDVSE--TRG 312
           S T+T     + T+  S +GS      TT   T   +    E +A ++ G + ++  T G
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 313 SE----GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSV 368
           SE      G +++A S+           +  TT ++ + F + + + T GS + +  S++
Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF-ETTAASTTGS-EPTMASTM 299

Query: 369 QSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTS 428
            S     S    +    S   +  S  T     G    +   V S +T +    +   T+
Sbjct: 300 GSETTMASTIGPETTKVS---TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 429 QPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE 488
                E S      S   T     A T G E  T   +  +    S  G      +    
Sbjct: 357 SIMGSETSTDSTTGSETTT-----ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 489 NVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRH 548
             +  + +  S  ++V++     T++S + S   + + S  S +  +S  GSE +     
Sbjct: 412 ETT-TTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS-DSETTTASTEGSETTTVTTA 469

Query: 549 DGACPT--TTFSELLNAIHNGIYNSNDVAV-SFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                T  TT SE   A + G+  +    + S     S  GS T   S+   + ++   +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTE 529

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSS 634
                + S   S    V+TT   T + S+
Sbjct: 530 GSENTTVSTTGSETTTVSTTGLETTTTST 558


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 111/523 (21%), Positives = 202/523 (38%), Gaps = 49/523 (9%)

Query: 496  SSASPTSSVASAAG-SITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRH---DGA 551
            +SA  TSS  +A G SI +S+  +  T      L+S+ V ++PV +  +        D  
Sbjct: 1429 TSAEATSSPTTAEGISIPTSTPSEGKT-----PLKSIPVSNTPVANSEASTLSTTPVDSN 1483

Query: 552  CPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALS 611
             P  T + + ++          +A+S P+  S + +S PVS++ +       L    A++
Sbjct: 1484 SPVVTSTAVSSSPTPA--EGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVT 1541

Query: 612  PSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAA---LIAQSENNQTDQDLG 668
             + V++ + A  ++   T  G+S+ Q  ++  G+   +S+     L+  SE N       
Sbjct: 1542 STPVTTYSQA--SSSPTTADGTSM-QTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598

Query: 669  DNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLP----PVAASIEQLLERQW 724
            D+   +    +S   S S  +  SS+ I     G+  L ++P    PVA+     L    
Sbjct: 1599 DSKTQVT---ASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTP 1655

Query: 725  SEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQ-LLNAQLSVPFP 783
             +    ++   T +++           +      E    LT+   R   + ++ +S    
Sbjct: 1656 VDSNSPVI---TSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLST 1712

Query: 784  TITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSS 843
            T   N +P     +  A+++PTT    S  +        P  S+PV    + SS  ST S
Sbjct: 1713 TPVDNSTPVTT--STEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS 1770

Query: 844  SSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALP 903
            ++ + T  P   S     S  +   +   +    L+ GM P+TST  + + V        
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTA--EGTSIPTSTLSEGMTPLTSTPVSHTLVAN------ 1822

Query: 904  GNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQ 963
                 ++      N  + T   +S +PTP   T++         AT T S     L S  
Sbjct: 1823 SEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI---------ATSTPSEGSTALTSIP 1873

Query: 964  QRQILIHQQQFQQLLNSQQL--TPVHRHPHFTQLPPTHFSPSM 1004
                 +   +   L  +  +  TPV  +   +  P T    SM
Sbjct: 1874 VSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSM 1916



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 144/720 (20%), Positives = 256/720 (35%), Gaps = 106/720 (14%)

Query: 251  PSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSET 310
            PS    P   +    T  ++S  S   +     DT+   T  +    S+ T+ G  +  +
Sbjct: 1037 PSEGSTPLTRMPVSTTMVASSETSTLSTTPA--DTSTPVTTYSQASSSSTTADGTSMPTS 1094

Query: 311  RGSEGKGKKSS---------AHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
              SEG    +S         +  +      P     P TT + AS  P  +   +  +  
Sbjct: 1095 TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSP 1154

Query: 362  SSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLP 421
             S G++  +     +        ++ S +   S T+     E+ S              P
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSP-------------P 1201

Query: 422  STSAVTSQPKSFENSPGDLGN--SSLP-------TAGYKRAQTSGIEEETVKEKKRKGNK 472
             T+ VTS P S   +PG+     +S+P       ++      TS ++  T      + + 
Sbjct: 1202 PTAEVTSMPTS---TPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSS 1258

Query: 473  QSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLS 532
                  G           S L  S    T+ V S      +S+L  +P   +   + S  
Sbjct: 1259 SPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPE----ASTLLTTPVDTKGPVVTSNE 1314

Query: 533  VGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGS--GSSTP 590
            V SSP  +E +       + PT+T+SE    + +   N+  VA S  +++S +   +STP
Sbjct: 1315 VSSSPTPAEGT-------SMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTP 1367

Query: 591  VSSS----HLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNR 646
            V++S      P  S G        S       +  V+TT   +   S+LS  P       
Sbjct: 1368 VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPV------ 1421

Query: 647  SNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSS- 705
              S+     A++ ++ T  +      +    G +P  S+    PVS+  +   +    S 
Sbjct: 1422 DTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSI----PVSNTPVANSEASTLST 1477

Query: 706  --LENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKN 763
              +++  PV  S         +EG    +   TPS+    L S+             +  
Sbjct: 1478 TPVDSNSPVVTSTAVSSSPTPAEGTSIAIS--TPSEGSTALTSI------------PVST 1523

Query: 764  LTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP 823
             T     +  L+       P +T+ P  ++      A ++PTT    S ++        P
Sbjct: 1524 TTVASSEINSLSTT-----PAVTSTPVTTYS----QASSSPTTADGTSMQTSTYSEGSTP 1574

Query: 824  DNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQ 883
              SLPV    + SS  +T S++ + +     Q  A   +  S   + + +T+   + G  
Sbjct: 1575 LTSLPVSTMLVVSSEANTLSTTPIDSKT---QVTASTEASSSTTAEGSSMTISTPSEGSP 1631

Query: 884  PVT----STIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVP 939
             +T    ST P  S     +   P +           N  + T   +S +PTP   T++P
Sbjct: 1632 LLTSIPVSTTPVASPEASTLSTTPVDS----------NSPVITSTEVSSSPTPAEGTSMP 1681



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 153/740 (20%), Positives = 263/740 (35%), Gaps = 119/740 (16%)

Query: 256  VPSLTV---TTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRG 312
            +P+ T+   TT  T    S+  ++ S      TT   +N  F      T+S +  S    
Sbjct: 2269 IPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPF------TTSTEASSPPPT 2322

Query: 313  SEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQ 372
            +EG    +S  S G         R P +T   AS F   + S TP    +   +  Q+  
Sbjct: 2323 AEGTSMPTSTSSEGNTPLT----RMPVSTTMVAS-FETSTLSTTPADTSTPVTTYSQAGS 2377

Query: 373  DFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKS 432
               +  D+ +   +YS       +  V      S E   +S + +    ST   TS   S
Sbjct: 2378 SPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVD--TSTPVTTSTEAS 2435

Query: 433  FENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSH 492
              +SP     +S+PT+      T                  S      P  +     +S 
Sbjct: 2436 --SSPTTAEGTSIPTSPPSEGTTP---------------LASMPVSTTPVVSSEAGTLST 2478

Query: 493  LSVSSASP-TSSVASAAGSITSSSLQKSPTLLRNGS--LQSLSVGSSPVGSEISMQYRH- 548
              V +++P T+S  +++   T+  +    +    GS  L S+ V ++PV S  +      
Sbjct: 2479 TPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTT 2538

Query: 549  --DGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGS----STPVSSSHLPQQSSG 602
              D   P  T +E+ ++       ++    S P      GS    S PVS+  L      
Sbjct: 2539 PVDSNSPVVTSTEISSSA------TSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASS--- 2589

Query: 603  HLQQVGALSPSAVSSAAPAVATTQAN----TLSGSSLS-QAPSHMYGNRSNSSMAALIAQ 657
               +   LS + V ++ P   +T+ +    T   +S+    PS +  + ++  ++ +   
Sbjct: 2590 ---EASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVA 2646

Query: 658  SENNQTDQDLGDNSRNLV----GRGSSP---RGSLSPRS-------PVSSLQIRYDQPGN 703
            S    T      ++R LV    G  SSP    GS  P S       P++++ +      N
Sbjct: 2647 SSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLAN 2706

Query: 704  SSLENLP--------PVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENR 755
            S    L         PV  S E       +EG    +   TPSD    L S+        
Sbjct: 2707 SEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIS--TPSDGSTPLTSI-------- 2756

Query: 756  RLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSP 815
             L   +   +++   +       S+P  T T             A ++PTT  + S  + 
Sbjct: 2757 -LVSTLPVASSEASTVSTTAVDTSIPVTTST------------EASSSPTTAEVTSMPTS 2803

Query: 816  HIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSG---VQQVNG 872
                +  P  S+PV +  + SS   T S++ + T  P   S     S  +    V  ++ 
Sbjct: 2804 TPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIST 2863

Query: 873  VTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTP 932
             + G+      PV ST P  S+    +   P +           +  + T    S +PT 
Sbjct: 2864 ASEGSTLLTSIPV-STTPVASSEASTLSTTPVD----------TSIPVTTSTEGSSSPTT 2912

Query: 933  LTHTTVPPNATHPMPATLTN 952
               T++P +    +   LT+
Sbjct: 2913 AEGTSMPISTPSEVSTPLTS 2932



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 150/709 (21%), Positives = 249/709 (35%), Gaps = 119/709 (16%)

Query: 251  PSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSET 310
            PS    P  ++    T   +S  S   +     DT+   T +     S  T+ G  +  +
Sbjct: 1744 PSEGTTPLTSIPVSTTPVLSSEASTLSATPI--DTSTPVTTSTEATSSPTTAEGTSIPTS 1801

Query: 311  RGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQS 370
              SEG    +S   S              T V + SP            V S++ SS  +
Sbjct: 1802 TLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPV-----------VTSTAVSSSPT 1850

Query: 371  PQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQP 430
            P +  S   S       + S+ S+A   +    +       N+ ST   + ST   T   
Sbjct: 1851 PAEGTSIATS-------TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ 1903

Query: 431  KSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENV 490
             S  +SP     SS+PT+             T +E             GRP        +
Sbjct: 1904 VS--SSPTTADGSSMPTS-------------TPRE-------------GRPP-------L 1928

Query: 491  SHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDG 550
            + + VS    T++VAS+  +  S++L  + T +   S Q+ S  ++  G+ +      +G
Sbjct: 1929 TSIPVS----TTTVASSEINTLSTTLADTRTPVTTYS-QASSSPTTADGTSMPTPAYSEG 1983

Query: 551  ACPTTTF---SELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQV 607
            + P T+    + L+ +      ++  V  S P   S  GSS+P ++     Q+S   ++ 
Sbjct: 1984 STPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERT 2043

Query: 608  GALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDL 667
              L       A   V+TT   +  G++LS  P       +NS+ A+  A +E +      
Sbjct: 2044 TPL-------AGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISA 2096

Query: 668  GDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSEG 727
                  L+   S P  +    SP +S         NS      PV  S E       +EG
Sbjct: 2097 PSEGSPLLT--SIPLSTTPVASPEASTLSTTPVDSNS------PVITSTEVSSSPIPTEG 2148

Query: 728  QQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITA 787
                ++  T SD    L S+             +         +  L+       P  T+
Sbjct: 2149 TS--MQTSTYSDRRTPLTSM------------PVSTTVVASSAISTLSTT-----PVDTS 2189

Query: 788  NPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSAL 847
             P  +    +  A+++PTT    S  +        P  S+PV    + +S  ST S++ +
Sbjct: 2190 TPVTN----STEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPV 2245

Query: 848  STPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQL 907
             T  P   S     S  +   +   +    L+ G  P+TS IP              + L
Sbjct: 2246 DTSTPVTTSTEATSSPTTA--EGTSIPTSTLSEGTTPLTS-IPV------------SHTL 2290

Query: 908  AINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASG 956
              N  V  L+    TPV  +   T  T  + PP          + S+ G
Sbjct: 2291 VANSEVSTLS---TTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEG 2336



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 147/738 (19%), Positives = 262/738 (35%), Gaps = 121/738 (16%)

Query: 259  LTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGK 318
            +T + E + + T+    S  +    D +   T+     +   +S    VS T        
Sbjct: 2723 VTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPV 2782

Query: 319  KSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFT 378
             +S  +S              T    ++P      + TP +  S +G+   +P D    T
Sbjct: 2783 TTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVA-SSEAGTLSTTPVD----T 2837

Query: 379  DSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPG 438
             + +   + + S  ++A + +    S + EG  ++  T I + +T   +S+  +   +P 
Sbjct: 2838 STPVTTSTKASSSPTTA-EGIVVPISTASEG--STLLTSIPVSTTPVASSEASTLSTTPV 2894

Query: 439  DLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGR-------------PKGNK 485
            D   +S+P        T G    T  E    G       P               P    
Sbjct: 2895 D---TSIPVT----TSTEGSSSPTTAE----GTSMPISTPSEVSTPLTSILVSTVPVAGS 2943

Query: 486  NQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLL---RNGSLQSLSVGSSPVGS-E 541
                +S   V + +P ++ A A+ S T++     P      R   L S+SV + PV S E
Sbjct: 2944 EASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSE 3003

Query: 542  ISMQYRH--DGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQ 599
             S   R   D + P TT +E  ++          + +S P+  S   +S PVS++ +   
Sbjct: 3004 ASTLSRTPADTSTPVTTSTEASSSPTTA--EGTGIPISTPSEGSTPLTSIPVSTTPVA-- 3059

Query: 600  SSGHLQQVGALSPSAVSSAAPAVATTQANT---------LSGSSLSQAPSHMYGNRSNSS 650
                + +   LS + V S +P V +T+ ++         +  S+ S+  + + G   +++
Sbjct: 3060 ----IPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTT 3115

Query: 651  MAALIAQSENNQTDQDLGDNSRNLVGRGSSP---RGSLSPRS------------PVSSLQ 695
                 A S  + T  D            SSP    G+  P S            PVS++ 
Sbjct: 3116 PVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTML 3175

Query: 696  IRYDQPGNSS---LENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQV 752
            +   +    S   ++   PV  S E       +EG    +   TPS+ +  L S+     
Sbjct: 3176 VVSSEDSTLSATPVDTSTPVTTSTEATSSTT-AEGTS--IPTSTPSEGMTPLTSV----- 3227

Query: 753  ENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSS 812
                    + N         +L+         +T +   S    T    + PT+      
Sbjct: 3228 -------PVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTS------ 3274

Query: 813  KSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNG 872
             +P  G++  P  S+PV    + SS  ST S++   T  P   +   Q S    +     
Sbjct: 3275 -TPSEGST--PLTSMPVSTTTVASSETSTLSTTPADTSTPV--TTYSQASSSPPIADGTS 3329

Query: 873  VTVGALASGMQPVT----STIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQ 928
            +     + G  P+T    ST P VS+    +   P +                TPVT S 
Sbjct: 3330 MPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVD--------------TSTPVTTST 3375

Query: 929  ----NPTPLTHTTVPPNA 942
                +PT    T++P ++
Sbjct: 3376 EASLSPTTAEGTSIPTSS 3393



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 149/761 (19%), Positives = 278/761 (36%), Gaps = 108/761 (14%)

Query: 251  PSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSET 310
            PS  + P  +V    T  ++S  SI  +     D+    T +     S  T+ G  +  +
Sbjct: 3217 PSEGMTPLTSVPVSNTPVASSEASILSTTP--VDSNTPLTTSTEASSSPPTAEGTSMPTS 3274

Query: 311  RGSEGKGKKSS---------AHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
              SEG    +S         +  +      P     P TT S AS  P  +  GT  S+ 
Sbjct: 3275 TPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIA-DGT--SMP 3331

Query: 362  SSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLP 421
            +S+ S   +P   +SF+ + +   S   S  S+   D     + S E  ++  +      
Sbjct: 3332 TSTYSEGSTPLTNMSFSTTPVV--SSEASTLSTTPVDTSTPVTTSTEASLSPTTA----E 3385

Query: 422  STSAVTSQPKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPG 479
             TS  TS P         +  S+ P    +     T+ ++  T+     + +       G
Sbjct: 3386 GTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEG 3445

Query: 480  RP-KGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPV 538
                 +   E  + LS+   S T   +S A +++++ +  S  +       S    SSP 
Sbjct: 3446 TSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTT-----SSPTNSSPT 3500

Query: 539  GSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGS--GSSTPVSSSHL 596
             +E++       + PT+T  E    + N   ++  VA S  + +S +   S+T V+SS  
Sbjct: 3501 TAEVT-------SMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQ 3553

Query: 597  PQQSSGHLQQV---------GALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRS 647
               S   LQ           G+ S + +  ++  V +++A+T S  S+ ++       +S
Sbjct: 3554 ASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQS 3613

Query: 648  NSSMA-------------------ALIAQSENNQTDQDLGDNSRNLVGRGS----SPRGS 684
            NS+                      ++  S  + T  + G  S   V   +    S + S
Sbjct: 3614 NSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVS 3673

Query: 685  LSPRSPV-SSLQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGM 743
             SP +P  +++ I     G++ L  +P     +        SEG        TPS +   
Sbjct: 3674 SSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTS------SEGSTL----STPSVVTST 3723

Query: 744  LKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQI--HTFSAQ 801
              +     + +    +      +    +  L   + V    +T  P  S       +++ 
Sbjct: 3724 PVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSM 3783

Query: 802  TAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTS------SGQSTSSSSALSTPPPAGQ 855
            +  T    +SS +   G + +P ++    +  LT+      S  S S +S LSTPP    
Sbjct: 3784 SMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTS 3843

Query: 856  SP---AQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGNQLAINGI 912
            +P   + +    S   +V  + +   +    P+T+ + + +    +  + PG  +A    
Sbjct: 3844 TPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTT----LPTSFPGASIA---- 3895

Query: 913  VGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNS 953
                      P+  S   TP T T   P  T P+  T++ S
Sbjct: 3896 -------STPPLDTSTTFTPSTDTASTP--TIPVATTISVS 3927



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 156/785 (19%), Positives = 273/785 (34%), Gaps = 94/785 (11%)

Query: 259  LTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGK 318
            +T + E + + T+    S  +    +     T+ +   +   +S    +S T        
Sbjct: 2959 VTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPV 3018

Query: 319  KSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFT 378
             +S  +S       G G    T    ++P      S TP ++  +S  S  +P D     
Sbjct: 3019 TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLST-TPVD----- 3072

Query: 379  DSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLP-STSAVTSQPKS-FENS 436
                 N     S + S++    +G S          + L G+P ST+ VTS   S    +
Sbjct: 3073 ----SNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128

Query: 437  PGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKG-----NKNQENVS 491
            P D   +S P      A +S    E         ++ S      P       +     +S
Sbjct: 3129 PVD---TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLS 3185

Query: 492  HLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGS--LQSLSVGSSPVGSE---ISMQY 546
               V +++P ++   A  S T+       +    G   L S+ V ++PV S    I    
Sbjct: 3186 ATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTT 3245

Query: 547  RHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQ 606
              D   P TT +E  ++          +  S P+  S   +S PVS++ +         +
Sbjct: 3246 PVDSNTPLTTSTEASSSPPTA--EGTSMPTSTPSEGSTPLTSMPVSTTTVASS------E 3297

Query: 607  VGALSPSAVSSAAPAVATTQANT----LSGSSLSQAPSHMYGNRSN-----SSMAALIAQ 657
               LS +   ++ P    +QA++      G+S+   P+  Y   S      S     +  
Sbjct: 3298 TSTLSTTPADTSTPVTTYSQASSSPPIADGTSM---PTSTYSEGSTPLTNMSFSTTPVVS 3354

Query: 658  SENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPV-SSLQIRYDQPGNSSLENLP----PV 712
            SE +       D S  +    +S   SLSP +   +S+       G + L ++P    PV
Sbjct: 3355 SEASTLSTTPVDTSTPVT---TSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPV 3411

Query: 713  AASIEQLLERQWSEGQQFLLE--QGTPSDILGMLKSLHQLQVENRRLEEQIKNLT----A 766
             +S    L     +    +    + + S  +    SL             I  L+    A
Sbjct: 3412 VSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVA 3471

Query: 767  KKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNS 826
              E   L    +    P  T++P+ S          +PTT  + S  +   G     + S
Sbjct: 3472 SSEASTLSTTPVDTSTPVTTSSPTNS----------SPTTAEVTSMPTSTAG-----EGS 3516

Query: 827  LPVLNQDLTSSGQSTSSSSALSTPPPAGQ---SPAQQGSGVSGVQQVNGVTVGALASGMQ 883
             P+ N  ++++  ++S +S LST P       + + Q S      QV  + +   + G  
Sbjct: 3517 TPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSS 3576

Query: 884  PVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMS--QNPTPLTHTTVPPN 941
             +T+ + + + V     + P                  TPVT S   N TP    T P  
Sbjct: 3577 SLTTMLLSSTYVTSSEASTPSTPSVDR----------STPVTTSTQSNSTP----TPPEV 3622

Query: 942  ATHPMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFS 1001
             T PM +T +  ++ L ++      + I +      L     TPV      +  P T   
Sbjct: 3623 ITLPM-STPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG 3681

Query: 1002 PSMEI 1006
             +M I
Sbjct: 3682 TTMPI 3686



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 157/798 (19%), Positives = 269/798 (33%), Gaps = 138/798 (17%)

Query: 252  SPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETR 311
            S    P  ++    T  +TS  +IS       DT+   TN+     S  TS G  +  + 
Sbjct: 861  SEGRTPLTSMPVSTTLVATS--AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 918

Query: 312  GSEGKGKKSSAHSSGQR---------GRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKS 362
              EG    +S   S               P     P TT + A+  P  +   +  +   
Sbjct: 919  PGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP 978

Query: 363  SSGSS------------VQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGG 410
            S G++              S    LS T  D  N   + S ++S+     +G S      
Sbjct: 979  SEGTTPLTSTPVSHTLVANSEASTLSTTPVD-SNTPLTTSTEASSPPPTAEGTSMPTSTP 1037

Query: 411  VNSFSTLIGLP--STSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKR 468
                + L  +P  +T   +S+  +   +P D   +S P   Y +A +S    +       
Sbjct: 1038 SEGSTPLTRMPVSTTMVASSETSTLSTTPAD---TSTPVTTYSQASSSSTTADGTSMPTS 1094

Query: 469  KGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSI---TSSSLQKSPTLLRN 525
              ++ S      P   +       L VSS + T S      SI   TS+    SPT    
Sbjct: 1095 TYSEGSTPLTSVPVSTR-------LVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG 1147

Query: 526  GSLQSL--SVGSSPVGSE-------ISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAV 576
             S+ +   S G++P+ S        +S +       P  + +++  +             
Sbjct: 1148 TSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVT 1207

Query: 577  SFPNVVSGSGSSTPVSSS---HLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGS 633
            S P    G   STP++S    H P  SS    +   LS S V ++ P   TT A T S  
Sbjct: 1208 SMPTSTPGE-RSTPLTSMPVRHTPVASS----EASTLSTSPVDTSTPV--TTSAETSSSP 1260

Query: 634  SLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSS 693
            + ++  S      S +S  + +  S    T       +  L+      +G +   + VSS
Sbjct: 1261 TTAEGTSLP---TSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSS 1317

Query: 694  LQIRYDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVE 753
                             P  A    +    +SEG+       TP   + +  +L      
Sbjct: 1318 ----------------SPTPAEGTSMPTSTYSEGR-------TPLTSIPVNTTL------ 1348

Query: 754  NRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSK 813
                               + ++ +S+   T   N +P     +  A ++PTT    S  
Sbjct: 1349 -------------------VASSAISILSTTPVDNSTPVTT--STEACSSPTTSEGTSMP 1387

Query: 814  SPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGV 873
            + +      P  S+PV    + SS  ST S++ + T  P G + A+  S  +  + ++ +
Sbjct: 1388 NSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTP-GTTSAEATSSPTTAEGIS-I 1445

Query: 874  TVGALASGMQPV----TSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQN 929
                 + G  P+     S  P  ++    +   P +           N  + T   +S +
Sbjct: 1446 PTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDS----------NSPVVTSTAVSSS 1495

Query: 930  PTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQQRQILIHQQQFQQLLNSQQL--TPVH 987
            PTP   T++         A  T S     L S       +   +   L  +  +  TPV 
Sbjct: 1496 PTPAEGTSI---------AISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVT 1546

Query: 988  RHPHFTQLPPTHFSPSME 1005
             +   +  P T    SM+
Sbjct: 1547 TYSQASSSPTTADGTSMQ 1564



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 106/533 (19%), Positives = 196/533 (36%), Gaps = 68/533 (12%)

Query: 477 GPGRPKGNKNQENVSH-LSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGS 535
           G   P    ++E++S  ++  S +P  S   A  S+T      +P      S Q+ S  +
Sbjct: 144 GTDVPMSTPSEESISSTMAFVSTAPLPSF-EAYTSLTYKVDMSTPLTT---STQASSSPT 199

Query: 536 SPVGSEISMQYRHDGACPTTTF--SELLNAIHNGI-YNSNDVAVSFPNVVSGSGSSTPVS 592
           +P  + I      +G+ P T+   S +  A    I   +  V +S P  +S   SS+P +
Sbjct: 200 TPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTT 259

Query: 593 ------SSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANT----LSGSSLSQAPSHM 642
                 S+  P   S  L ++       VSS A  ++TT A T    ++ +  S +P+  
Sbjct: 260 AEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTA 319

Query: 643 YGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPG 702
            G          I  S   +    L     + +   +S   +LS  +PV +  +      
Sbjct: 320 EGTS--------IPTSTYTEGSTPLTSTPASTMPVATSEMSTLS-ITPVDTSTLVTTSTE 370

Query: 703 NSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGM--LKSLHQLQVENRRL--- 757
            SSL    P  A    +L    SEG   L      + ++      +   + V+++     
Sbjct: 371 PSSL----PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTT 426

Query: 758 --EEQIKNLTAKKERLQLLN-AQLSVPFPTITANPSPSHQIHTFSAQTAP-------TTD 807
             E      TA+   +     ++ S P  ++  + +P       +  T P       TT 
Sbjct: 427 ASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTS 486

Query: 808 SLNSSKSPHIGNSFLP-----DNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSP---AQ 859
           +  SS  P    + +P     + S P+ +  +++   ++S +S LST P    +P   + 
Sbjct: 487 TEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSS 546

Query: 860 QGSGVSGVQQVNGVTVGALASGMQPVT----STIPAVSAVGGIIGALPGNQLAINGIVGA 915
           + S  S   +   +     + G  P+T    ST   VS+        P +          
Sbjct: 547 EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADS--------- 597

Query: 916 LNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQQRQIL 968
            N  + T    S + T    T++P +       T+T+ +    L++  +   L
Sbjct: 598 -NTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTL 649



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 143/741 (19%), Positives = 258/741 (34%), Gaps = 93/741 (12%)

Query: 260  TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKK 319
            T T  +  T+ ++ S+S +L    + +   T          TS+    S T  +EG    
Sbjct: 621  TSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTT-AEGTSMP 679

Query: 320  SSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTD 379
            +S ++ G     P       TT+ A+S     + S TP    +   +S ++     +   
Sbjct: 680  TSTYTEGST---PLTSMPVNTTLVASSE--ASTLSTTPVDTSTPVTTSTEASSSPTTADG 734

Query: 380  SDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGD 439
            + +   + S       +  V K    S E    S + L      +  T    S   + G 
Sbjct: 735  ASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGT 794

Query: 440  LGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSAS 499
                S P+ G     +  +    V   +      +      P     + + S       S
Sbjct: 795  SMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTS 854

Query: 500  -PTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTFS 558
             PTS+ +     +TS  +  S TL+   ++ +LS  ++PV          D + P T  +
Sbjct: 855  MPTSTYSEGRTPLTSMPV--STTLVATSAISTLS--TTPV----------DTSTPVTNST 900

Query: 559  ELLNAIHNGIYNSNDVAVSFPNVVSGSGSS--TPVSSSHLPQQSSGHLQQVGALSPSAVS 616
            E  ++       +     S P    G GS+  T +  S  P  SS    +   LS + V 
Sbjct: 901  EARSS------PTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSS----EARTLSATPVD 950

Query: 617  SAAPAVATTQAN----TLSGSSL-SQAPSHMYGNRSNSSMA-ALIAQSENNQTDQDLGDN 670
            ++ P   +T+A     T  G+S+ +  PS      +++ ++  L+A SE +       D+
Sbjct: 951  TSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDS 1010

Query: 671  SRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPP----VAASIEQLLERQWSE 726
            +  L    S+   S  P +  +S+       G++ L  +P     VA+S    L    ++
Sbjct: 1011 NTPLTT--STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPAD 1068

Query: 727  GQQFLL------EQGTPSDILGMLKS--------LHQLQVENRRLEEQIKNLTAKKERLQ 772
                +          T +D   M  S        L  + V  R +      ++++   L 
Sbjct: 1069 TSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLV------VSSEASTLS 1122

Query: 773  LLNAQLSVPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQ 832
                  S+P  T T   S        S  T+P ++      S  +  + +  +    L+ 
Sbjct: 1123 TTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLST 1182

Query: 833  DLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTSTIPAV 892
                S    ++S+  S+PPP  +  +   S         G     L S   PV  T P  
Sbjct: 1183 TPVDSKTQVATSTEASSPPPTAEVTSMPTS-------TPGERSTPLTS--MPVRHT-PVA 1232

Query: 893  SAVGGIIGALPGNQLAINGIVGALNGVMQTPVT----MSQNPTPLTHTTVPPNATHPMPA 948
            S+    +   P +                TPVT     S +PT    T++P + T     
Sbjct: 1233 SSEASTLSTSPVD--------------TSTPVTTSAETSSSPTTAEGTSLPTSTTSEGST 1278

Query: 949  TLTNSASGLGLLSDQQRQILI 969
             LT+      L++  +   L+
Sbjct: 1279 LLTSIPVSTTLVTSPEASTLL 1299


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 127/728 (17%), Positives = 255/728 (35%), Gaps = 70/728 (9%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE--- 314
            S T +   T ++TS+ + + S +  E TT   T++    VS  T S + ++ T GSE   
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST-TGSERTITSTEGSETTT 675

Query: 315  -------------GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
                         G G  + + +  +  +    G    TT +  S     S +G+  +  
Sbjct: 676  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 362  SSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLP 421
            S+ GS   +     S   S+  + S + S+ ++A+    +    S  G   + ++ IG  
Sbjct: 736  STEGSETTT----ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 422  STSAVTSQPKS----FENSPGDLGN------SSLPTAGYKRAQTSGIEEETVKEKKRKGN 471
            +T   T+  K      ENS   + +      +++ TAG +    S    ET      +G+
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 472  KQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSL 531
            + +           + E     + S+ S  ++ A+  GS T+++  +        +  S 
Sbjct: 852  ETT---------TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE 902

Query: 532  SVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSGSSTP 590
            +  +S  GSEI+          +TT SE   A   G   +      S    VS +GS T 
Sbjct: 903  TTTASTEGSEIT--------TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954

Query: 591  VSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSS 650
              S+   + ++         + S   S    V+T  + T + +S+  + +    +  + +
Sbjct: 955  TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTT-ASIEGSETTTVSSTGSET 1013

Query: 651  MAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLE 707
                   +E   T  + G  +  +   GS      +  S  ++      +      +  E
Sbjct: 1014 TTVSTTGTETTITSTE-GSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE 1072

Query: 708  NLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAK 767
                  A +E         G       G+ +  + +  S              +   +++
Sbjct: 1073 TTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSE 1132

Query: 768  KERLQLLNAQLSVPFPTI----TANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP 823
                    ++++  F T+    T +   S    + +A +  TT S   S++     +   
Sbjct: 1133 TTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSE 1192

Query: 824  DNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQ 883
              +      + T++  S S ++   T      +P+  GS  +    +   T  A  + ++
Sbjct: 1193 TTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLE 1252

Query: 884  PVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNAT 943
            P  +++         I A        +G   A   V  T   +    T  T  ++ P   
Sbjct: 1253 PTATSLTGSETTTVSITA--------SGATAASTTVSSTTFVL----TKATDVSIQPITN 1300

Query: 944  HPMPATLT 951
             PM  T T
Sbjct: 1301 TPMSGTRT 1308



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 118/646 (18%), Positives = 221/646 (34%), Gaps = 53/646 (8%)

Query: 260  TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
            T  +E T  ST+++  + +     +TT+  T  +    ++ TSS    + T GSE     
Sbjct: 588  TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 647

Query: 315  -GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQD 373
                + +   ++G          +  TTVSA       S  G+  +  S +GS       
Sbjct: 648  TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTK--- 704

Query: 374  FLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSF 433
             +S T S+    S   S+ ++A+    +  + S EG   + ++  G  +TSA T+  ++ 
Sbjct: 705  -VSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETT 763

Query: 434  ENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
              S      +     G +    S I  ET K         +          +N E    +
Sbjct: 764  TASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF-------TENSETT--I 814

Query: 494  SVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP 553
            + ++AS T++V++A      +S   S T     +  S +  +S  GSE +          
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 554  TTTF--SELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALS 611
            T T   SE   A   G         S     S  GS T  +S+         +  V    
Sbjct: 875  TATTIGSETTTASTEG---------SETTTTSTEGSETTTAST-----EGSEITTVSTTG 920

Query: 612  PSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNS 671
                +++     TT A+T  GS L+        + + S    + A+     T   +G  +
Sbjct: 921  SETTTASTEGSETTTAST-EGSELTTV------STTGSETITVSAEGSETTTVTTMGSET 973

Query: 672  RNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLENLPPVAASIEQLLERQWSEGQ 728
                  GS      +  S  ++  I   +     ++  E         E  +    +EG 
Sbjct: 974  TTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS--TEGS 1031

Query: 729  QFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVP------F 782
            +        S+   +  +  +    +    E     T   E      A L          
Sbjct: 1032 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 783  PTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTS 842
             T TA+ + S     +   +  TT S   S++  +  +     +      ++T+   + S
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 843  SSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
             ++ +ST      + +  GS  +        T  A  +G +  T++
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 118/672 (17%), Positives = 235/672 (34%), Gaps = 71/672 (10%)

Query: 263  TEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE-------G 315
            +E T T T  + ++     + +TT   T  +   +++ + S    + T GSE       G
Sbjct: 411  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 316  KGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ------ 369
               K++  +  +       G    T  +  S     S  G+  +  S++GS +       
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 370  ----------SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIG 419
                      S    +S T  +    S   S+ ++ +    +  + S EG   + ++  G
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 420  LPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK------------RAQTSGIEEETVKEKK 467
              +T+  T+  ++   S  D   +S  T G +             A T G E  TV    
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 468  RKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGS 527
             +    S  G  R     + E     +VS+    ++V++     T+ S+  S T  +  +
Sbjct: 651  SETTMVSTTGSERT--ITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSET-TKVST 707

Query: 528  LQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSG 586
              S +  +S  GSEI+          + T SE   A   G   +      S     S +G
Sbjct: 708  TGSETTTTSTEGSEIT--------TASITGSETTTASTEGSETTTASTEGSETTSASTTG 759

Query: 587  SSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVAT---------TQANTLSGSSLSQ 637
            S T  +S+   + +   +        S + S    V+T         T+ +  + +S + 
Sbjct: 760  SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 819

Query: 638  APSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIR 697
            + +       + ++ A  A SE   T    G  +      GS    + +  S  ++    
Sbjct: 820  SETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI 879

Query: 698  YDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRL 757
              +   +S E       S         +EG +        S+I  +  +  +    +   
Sbjct: 880  GSETTTASTEGSETTTTS---------TEGSETTTASTEGSEITTVSTTGSETTTAS--- 927

Query: 758  EEQIKNLTAKKERLQLLNAQLS-VPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPH 816
             E  +  TA  E  +L     +     T++A  S +  + T  ++T  TT S   S++  
Sbjct: 928  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSET--TTASTAGSETTT 985

Query: 817  IGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVG 876
            +  +     +  +   + T+   + S ++ +ST        + +GS  + V      T  
Sbjct: 986  VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTA 1045

Query: 877  ALASGMQPVTST 888
               +G +  T++
Sbjct: 1046 VYTTGSETTTTS 1057



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 94/422 (22%), Positives = 159/422 (37%), Gaps = 70/422 (16%)

Query: 250 EPSPALVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSE 309
           E + +   S T T   T T T+  S  GS      TT+  T       S  T+     SE
Sbjct: 94  ETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE 153

Query: 310 TRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ 369
           T  +     +++A S+         G    T  +A S     S +G+  +  S++GS   
Sbjct: 154 TTTAYTADSETTAAST--------TGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETT 205

Query: 370 SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQ 429
           +    +S T S+    S +HS+ ++A+    +    S  G   + ST  G  +T+A T  
Sbjct: 206 T----VSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST-AGSETTAASTED 260

Query: 430 PKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQ 487
            ++      D   ++  T G++   A T+G E         +    S  GP   K     
Sbjct: 261 SETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK----- 315

Query: 488 ENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYR 547
                  VS+AS   +   AAGS T                    + +S VGSE +    
Sbjct: 316 -------VSTASSEVTTVFAAGSET--------------------IRASTVGSETT---- 344

Query: 548 HDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQV 607
                 +TT SE   A   G   S D         S +GS T  +S+   + ++   +  
Sbjct: 345 ----TVSTTGSETTTASIMGSETSTD---------STTGSETTTASTEGSETTTASTEGS 391

Query: 608 GALSPSAVSSAAPAVATTQANTLS----GSSLSQAPSHMYGNRSNSSMAA--LIAQSENN 661
            A + S   S    V+ T + T +    GS ++   + ++   + S+  +   IA + ++
Sbjct: 392 EATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDS 451

Query: 662 QT 663
           +T
Sbjct: 452 ET 453



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 95/465 (20%), Positives = 171/465 (36%), Gaps = 58/465 (12%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKG 317
            S T T   T T T+  S  GS      T    T A +   S  T++  + SET      G
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 318  KKSSAHSSGQRGRKPGGGRNPGTTV--SAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFL 375
             +++  S+             GTT   +A S       +G+  +  S+ GS   +    +
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATT----V 1126

Query: 376  SFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFEN 435
            S T S+    S + S+ ++    V +  + S  G   + S+  G  +T+  T   ++   
Sbjct: 1127 STTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTA 1186

Query: 436  SPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
            S      ++  TAG +   A TSG E  T      + +  S  G        ++ N + +
Sbjct: 1187 STAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--------SETNTAFI 1238

Query: 494  SVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP 553
                 S T+  ++A+   T++SL  S T   + +    +  S+ V S             
Sbjct: 1239 ---IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS------------- 1282

Query: 554  TTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPS 613
             TTF          +  + DV++    + +   S T  + + L   SS  +      + S
Sbjct: 1283 -TTFV---------LTKATDVSIQ--PITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1330

Query: 614  AVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNS-- 671
            A S   P +    +   + +  + + +  +G R+ +       +   + T Q+ G  S  
Sbjct: 1331 AASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS----TREPTSSTFQETGPVSMG 1386

Query: 672  RNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASI 716
             N V    +P   + P          Y QP    L +L  V A++
Sbjct: 1387 TNTVSMSHTPTNVIKPSG--------YLQPWAIILISLAAVVAAV 1423



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 108/653 (16%), Positives = 229/653 (35%), Gaps = 47/653 (7%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKK 319
           T+  E T  ST+++ ++       +T    T  +  E +  +++G   SET  +   G +
Sbjct: 308 TIGPETTKVSTASSEVTTVFAAGSETIRASTVGS--ETTTVSTTG---SETTTASIMGSE 362

Query: 320 SSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTD 379
           +S  S+         G    T  +  S     S  G+  +  S++GS   +    +S TD
Sbjct: 363 TSTDSTT--------GSETTTASTEGSETTTASTEGSEATTVSTTGSETTT----VSITD 410

Query: 380 SDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGD 439
           S+        S+ ++ +  V +  + S EG   + ++     +T+A T   ++   +   
Sbjct: 411 SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 470

Query: 440 LGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSS 497
               +  T G +   A  +G+E  TV          S  G      +     ++ +S   
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 498 ASPT--SSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTT 555
           +  T  S+  S   +++++ L+ + T      + ++S   +   ++ S +     A  T 
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD-STEGSGTTAASTA 589

Query: 556 TFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAV 615
                  +  +    +   A S     S +GS T  +S+   + ++   +     + S  
Sbjct: 590 GSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTT 649

Query: 616 SSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLV 675
            S    V+TT +     S+     + +    S ++++    +     T    G  +  + 
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSITGSETTKVS 706

Query: 676 GRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWS-EGQQFLLEQ 734
             GS    + +  S +++  I   +   +S E      AS E       S  G +     
Sbjct: 707 TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 766

Query: 735 GTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQ 794
            T S+         +  + +    E  K  TA  +   +          + TA  S +  
Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA--SETTT 824

Query: 795 IHTFSAQTAP-------------------TTDSLNSSKSPHIGNSFLPDNSLPVLNQDLT 835
           + T  ++T P                   TT S   S++           +   +  + T
Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 836 SSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
           ++    S ++  ST      + + +GS ++ V      T  A   G +  T++
Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 89/422 (21%), Positives = 156/422 (36%), Gaps = 25/422 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARF----TNANFQEVSAHTSSGKDVSETRGSEG 315
           T+ +E T  ST+ +  + S    E T A      TN  F E S  T++     ET  +  
Sbjct: 229 TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 316 KGKKSSAHSSGQRGRKPGGGRNPGTT-VSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDF 374
            G + +  S+            P TT VS AS      F+    ++++   S+V S    
Sbjct: 289 TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA---STVGSETTT 345

Query: 375 LSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFE 434
           +S T S+    S   S+ S+ +    +  + S EG   + ++  G  +T+  T+  ++  
Sbjct: 346 VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405

Query: 435 NSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLS 494
            S  D   ++  T G +    S    ET                       + E     +
Sbjct: 406 VSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTT 465

Query: 495 VSSASPTSSVASAAGSITSSSLQ---KSPTLLRNGS-------LQSLSVGSSPVGSEISM 544
           V++A   +  A   GS T+++     ++ T+   GS         S +   S  GSE++ 
Sbjct: 466 VTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTT 525

Query: 545 QYRH--DGACPTTTFSELLNAIHNGI-YNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSS 601
                 +    +TT SE       G+   +     S    VS +G+ T   S+    + S
Sbjct: 526 VSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST----EGS 581

Query: 602 GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENN 661
           G      A S +   S A +  TT +   S ++ +          S +S     A +E +
Sbjct: 582 GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS 641

Query: 662 QT 663
           +T
Sbjct: 642 ET 643



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 82/426 (19%), Positives = 159/426 (37%), Gaps = 39/426 (9%)

Query: 256  VPSLTVTTEKTYTSTSNNS--ISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGS 313
            +P+ T  +E T T+++  S   + S +  E TTA   +    E +  T+ G + + T  +
Sbjct: 833  IPASTAGSETTTTTSTEGSETTTASTEGSETTTA---STESSETTTATTIGSETT-TAST 888

Query: 314  EGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ---- 369
            EG    +++    +       G    T  +  S     S  G+  +  S+ GS +     
Sbjct: 889  EGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVST 948

Query: 370  --------SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGES----GSQEGGVNSFSTL 417
                    S +   + T + + +++ + S   S T  V    S     S EG   +  + 
Sbjct: 949  TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008

Query: 418  IGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHG 477
             G  +T+  T+  ++   S      +++ TAG +         ET           +   
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068

Query: 478  PGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSS---SLQKSPTLLRNGS------- 527
             G      +  ++   +VS++   ++ AS AGS T++   +  K+ T    GS       
Sbjct: 1069 TGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVST 1128

Query: 528  LQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGS 587
              S +  +S  GSE++  +       TTT S +          ++  A S     S  GS
Sbjct: 1129 TSSETTTASTTGSEMTTVF--TTVSETTTVSTI-----GSEATTSSAAGSEATTTSTEGS 1181

Query: 588  STPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRS 647
             T  +S+   + ++         + S   S      TT + T + SS     +  +   S
Sbjct: 1182 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1241

Query: 648  NSSMAA 653
             +++A+
Sbjct: 1242 ETTIAS 1247



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 85/470 (18%), Positives = 165/470 (35%), Gaps = 25/470 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
           T ++E T TST+ +  +       +TT  +T  +    ++ T S      T GSE     
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 188

Query: 315 --GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSG-----SS 367
             G    + + +  +       G    T  +A S     S  G+  +  S++G     S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 368 VQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVT 427
             S     S  DS+        S+ ++A+    +  + S  G   + ++ +G  +T A T
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 308

Query: 428 SQPKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNK 485
             P++ + S      +++  AG +  RA T G E  TV     +    S  G      + 
Sbjct: 309 IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 486 NQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQ 545
                +  S   +  T++    + + T S+     T +      S +  +   GSE++  
Sbjct: 369 TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV--SITDSETTTTCTEGSEMT-- 424

Query: 546 YRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                A  TT F     +           + S     S  GS T   ++   +  + +  
Sbjct: 425 -----AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTT 479

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQ 665
                + S        V T  ++T + S+     + +  + + S M  +  +   N T  
Sbjct: 480 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV--SATGSEMTTVSTEGSENTTVS 537

Query: 666 DLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAAS 715
             G  +  +   G     + +  S ++++     +    S E     AAS
Sbjct: 538 TTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 587



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 79/389 (20%), Positives = 143/389 (36%), Gaps = 24/389 (6%)

Query: 258 SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFT---NANFQEVSAHTSSGKDVSE--TRG 312
           S T+T     + T+  S +GS      TT   T   +    E +A ++ G + ++  T G
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241

Query: 313 SE----GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSV 368
           SE      G +++A S+           +  TT ++ + F + + + T GS + +  S++
Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF-ETTAASTTGS-EPTMASTM 299

Query: 369 QSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTS 428
            S     S    +    S   +  S  T     G    +   V S +T +    +   T+
Sbjct: 300 GSETTMASTIGPETTKVS---TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 429 QPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE 488
                E S      S   T     A T G E  T   +  +    S  G      +    
Sbjct: 357 SIMGSETSTDSTTGSETTT-----ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 489 NVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRH 548
             +  + +  S  ++V++     T++S + S   + + S  S +  +S  GSE +     
Sbjct: 412 ETT-TTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS-DSETTTASTEGSETTTVTTA 469

Query: 549 DGACPT--TTFSELLNAIHNGIYNSNDVAV-SFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                T  TT SE   A + G+  +    + S     S  GS T   S+   + ++   +
Sbjct: 470 GSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTE 529

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSS 634
                + S   S    V+TT   T + S+
Sbjct: 530 GSENTTVSTTGSETTTVSTTGLETTTTST 558


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 127/728 (17%), Positives = 255/728 (35%), Gaps = 70/728 (9%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE--- 314
            S T +   T ++TS+ + + S +  E TT   T++    VS  T S + ++ T GSE   
Sbjct: 638  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST-TGSERTITSTEGSETTT 696

Query: 315  -------------GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVK 361
                         G G  + + +  +  +    G    TT +  S     S +G+  +  
Sbjct: 697  VSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 756

Query: 362  SSSGSSVQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLP 421
            S+ GS   +     S   S+  + S + S+ ++A+    +    S  G   + ++ IG  
Sbjct: 757  STEGSETTT----ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 812

Query: 422  STSAVTSQPKS----FENSPGDLGN------SSLPTAGYKRAQTSGIEEETVKEKKRKGN 471
            +T   T+  K      ENS   + +      +++ TAG +    S    ET      +G+
Sbjct: 813  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 872

Query: 472  KQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSL 531
            + +           + E     + S+ S  ++ A+  GS T+++  +        +  S 
Sbjct: 873  ETT---------TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE 923

Query: 532  SVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSGSSTP 590
            +  +S  GSEI+          +TT SE   A   G   +      S    VS +GS T 
Sbjct: 924  TTTASTEGSEIT--------TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 975

Query: 591  VSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSS 650
              S+   + ++         + S   S    V+T  + T + +S+  + +    +  + +
Sbjct: 976  TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTT-ASIEGSETTTVSSTGSET 1034

Query: 651  MAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLE 707
                   +E   T  + G  +  +   GS      +  S  ++      +      +  E
Sbjct: 1035 TTVSTTGTETTITSTE-GSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSE 1093

Query: 708  NLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAK 767
                  A +E         G       G+ +  + +  S              +   +++
Sbjct: 1094 TTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSE 1153

Query: 768  KERLQLLNAQLSVPFPTI----TANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLP 823
                    ++++  F T+    T +   S    + +A +  TT S   S++     +   
Sbjct: 1154 TTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSE 1213

Query: 824  DNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQ 883
              +      + T++  S S ++   T      +P+  GS  +    +   T  A  + ++
Sbjct: 1214 TTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLE 1273

Query: 884  PVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNAT 943
            P  +++         I A        +G   A   V  T   +    T  T  ++ P   
Sbjct: 1274 PTATSLTGSETTTVSITA--------SGATAASTTVSSTTFVL----TKATDVSIQPITN 1321

Query: 944  HPMPATLT 951
             PM  T T
Sbjct: 1322 TPMSGTRT 1329



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 118/646 (18%), Positives = 221/646 (34%), Gaps = 53/646 (8%)

Query: 260  TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
            T  +E T  ST+++  + +     +TT+  T  +    ++ TSS    + T GSE     
Sbjct: 609  TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 668

Query: 315  -GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQD 373
                + +   ++G          +  TTVSA       S  G+  +  S +GS       
Sbjct: 669  TTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTK--- 725

Query: 374  FLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSF 433
             +S T S+    S   S+ ++A+    +  + S EG   + ++  G  +TSA T+  ++ 
Sbjct: 726  -VSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETT 784

Query: 434  ENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
              S      +     G +    S I  ET K         +          +N E    +
Sbjct: 785  TASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVF-------TENSETT--I 835

Query: 494  SVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP 553
            + ++AS T++V++A      +S   S T     +  S +  +S  GSE +          
Sbjct: 836  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 895

Query: 554  TTTF--SELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALS 611
            T T   SE   A   G         S     S  GS T  +S+         +  V    
Sbjct: 896  TATTIGSETTTASTEG---------SETTTTSTEGSETTTAST-----EGSEITTVSTTG 941

Query: 612  PSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNS 671
                +++     TT A+T  GS L+        + + S    + A+     T   +G  +
Sbjct: 942  SETTTASTEGSETTTAST-EGSELTTV------STTGSETITVSAEGSETTTVTTMGSET 994

Query: 672  RNLVGRGSSPRGSLSPRSPVSSLQIRYDQP---GNSSLENLPPVAASIEQLLERQWSEGQ 728
                  GS      +  S  ++  I   +     ++  E         E  +    +EG 
Sbjct: 995  TTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS--TEGS 1052

Query: 729  QFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVP------F 782
            +        S+   +  +  +    +    E     T   E      A L          
Sbjct: 1053 ETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGS 1112

Query: 783  PTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTS 842
             T TA+ + S     +   +  TT S   S++  +  +     +      ++T+   + S
Sbjct: 1113 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1172

Query: 843  SSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
             ++ +ST      + +  GS  +        T  A  +G +  T++
Sbjct: 1173 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1218



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 118/672 (17%), Positives = 235/672 (34%), Gaps = 71/672 (10%)

Query: 263  TEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE-------G 315
            +E T T T  + ++     + +TT   T  +   +++ + S    + T GSE       G
Sbjct: 432  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 491

Query: 316  KGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ------ 369
               K++  +  +       G    T  +  S     S  G+  +  S++GS +       
Sbjct: 492  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 551

Query: 370  ----------SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIG 419
                      S    +S T  +    S   S+ ++ +    +  + S EG   + ++  G
Sbjct: 552  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 611

Query: 420  LPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK------------RAQTSGIEEETVKEKK 467
              +T+  T+  ++   S  D   +S  T G +             A T G E  TV    
Sbjct: 612  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 671

Query: 468  RKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGS 527
             +    S  G  R     + E     +VS+    ++V++     T+ S+  S T  +  +
Sbjct: 672  SETTMVSTTGSERT--ITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSET-TKVST 728

Query: 528  LQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSN-DVAVSFPNVVSGSG 586
              S +  +S  GSEI+          + T SE   A   G   +      S     S +G
Sbjct: 729  TGSETTTTSTEGSEIT--------TASITGSETTTASTEGSETTTASTEGSETTSASTTG 780

Query: 587  SSTPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVAT---------TQANTLSGSSLSQ 637
            S T  +S+   + +   +        S + S    V+T         T+ +  + +S + 
Sbjct: 781  SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 840

Query: 638  APSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIR 697
            + +       + ++ A  A SE   T    G  +      GS    + +  S  ++    
Sbjct: 841  SETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI 900

Query: 698  YDQPGNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGMLKSLHQLQVENRRL 757
              +   +S E       S         +EG +        S+I  +  +  +    +   
Sbjct: 901  GSETTTASTEGSETTTTS---------TEGSETTTASTEGSEITTVSTTGSETTTAS--- 948

Query: 758  EEQIKNLTAKKERLQLLNAQLS-VPFPTITANPSPSHQIHTFSAQTAPTTDSLNSSKSPH 816
             E  +  TA  E  +L     +     T++A  S +  + T  ++T  TT S   S++  
Sbjct: 949  TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSET--TTASTAGSETTT 1006

Query: 817  IGNSFLPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVG 876
            +  +     +  +   + T+   + S ++ +ST        + +GS  + V      T  
Sbjct: 1007 VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTA 1066

Query: 877  ALASGMQPVTST 888
               +G +  T++
Sbjct: 1067 VYTTGSETTTTS 1078



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 95/465 (20%), Positives = 171/465 (36%), Gaps = 58/465 (12%)

Query: 258  SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKG 317
            S T T   T T T+  S  GS      T    T A +   S  T++  + SET      G
Sbjct: 1032 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1091

Query: 318  KKSSAHSSGQRGRKPGGGRNPGTTV--SAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFL 375
             +++  S+             GTT   +A S       +G+  +  S+ GS   +    +
Sbjct: 1092 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATT----V 1147

Query: 376  SFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFEN 435
            S T S+    S + S+ ++    V +  + S  G   + S+  G  +T+  T   ++   
Sbjct: 1148 STTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTA 1207

Query: 436  SPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHL 493
            S      ++  TAG +   A TSG E  T      + +  S  G        ++ N + +
Sbjct: 1208 STAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--------SETNTAFI 1259

Query: 494  SVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACP 553
                 S T+  ++A+   T++SL  S T   + +    +  S+ V S             
Sbjct: 1260 ---IGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS------------- 1303

Query: 554  TTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPS 613
             TTF          +  + DV++    + +   S T  + + L   SS  +      + S
Sbjct: 1304 -TTFV---------LTKATDVSIQ--PITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1351

Query: 614  AVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNS-- 671
            A S   P +    +   + +  + + +  +G R+ +       +   + T Q+ G  S  
Sbjct: 1352 AASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS----TREPTSSTFQETGPVSMG 1407

Query: 672  RNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASI 716
             N V    +P   + P          Y QP    L +L  V A++
Sbjct: 1408 TNTVSMSHTPTNVIKPSG--------YLQPWAIILISLAAVVAAV 1444



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 108/653 (16%), Positives = 229/653 (35%), Gaps = 47/653 (7%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSEGKGKK 319
           T+  E T  ST+++ ++       +T    T  +  E +  +++G   SET  +   G +
Sbjct: 329 TIGPETTKVSTASSEVTTVFAAGSETIRASTVGS--ETTTVSTTG---SETTTASIMGSE 383

Query: 320 SSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDFLSFTD 379
           +S  S+         G    T  +  S     S  G+  +  S++GS   +    +S TD
Sbjct: 384 TSTDSTT--------GSETTTASTEGSETTTASTEGSEATTVSTTGSETTT----VSITD 431

Query: 380 SDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGD 439
           S+        S+ ++ +  V +  + S EG   + ++     +T+A T   ++   +   
Sbjct: 432 SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAG 491

Query: 440 LGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSS 497
               +  T G +   A  +G+E  TV          S  G      +     ++ +S   
Sbjct: 492 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 551

Query: 498 ASPT--SSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTT 555
           +  T  S+  S   +++++ L+ + T      + ++S   +   ++ S +     A  T 
Sbjct: 552 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD-STEGSGTTAASTA 610

Query: 556 TFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSPSAV 615
                  +  +    +   A S     S +GS T  +S+   + ++   +     + S  
Sbjct: 611 GSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTT 670

Query: 616 SSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLV 675
            S    V+TT +     S+     + +    S ++++    +     T    G  +  + 
Sbjct: 671 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS---TEGSGTTTVSITGSETTKVS 727

Query: 676 GRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAASIEQLLERQWS-EGQQFLLEQ 734
             GS    + +  S +++  I   +   +S E      AS E       S  G +     
Sbjct: 728 TTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAS 787

Query: 735 GTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTITANPSPSHQ 794
            T S+         +  + +    E  K  TA  +   +          + TA  S +  
Sbjct: 788 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA--SETTT 845

Query: 795 IHTFSAQTAP-------------------TTDSLNSSKSPHIGNSFLPDNSLPVLNQDLT 835
           + T  ++T P                   TT S   S++           +   +  + T
Sbjct: 846 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 905

Query: 836 SSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQQVNGVTVGALASGMQPVTST 888
           ++    S ++  ST      + + +GS ++ V      T  A   G +  T++
Sbjct: 906 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 958



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 89/422 (21%), Positives = 156/422 (36%), Gaps = 25/422 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARF----TNANFQEVSAHTSSGKDVSETRGSEG 315
           T+ +E T  ST+ +  + S    E T A      TN  F E S  T++     ET  +  
Sbjct: 250 TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 309

Query: 316 KGKKSSAHSSGQRGRKPGGGRNPGTT-VSAASPFPQGSFSGTPGSVKSSSGSSVQSPQDF 374
            G + +  S+            P TT VS AS      F+    ++++   S+V S    
Sbjct: 310 TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA---STVGSETTT 366

Query: 375 LSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSFE 434
           +S T S+    S   S+ S+ +    +  + S EG   + ++  G  +T+  T+  ++  
Sbjct: 367 VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 426

Query: 435 NSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQENVSHLS 494
            S  D   ++  T G +    S    ET                       + E     +
Sbjct: 427 VSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTT 486

Query: 495 VSSASPTSSVASAAGSITSSSLQ---KSPTLLRNGS-------LQSLSVGSSPVGSEISM 544
           V++A   +  A   GS T+++     ++ T+   GS         S +   S  GSE++ 
Sbjct: 487 VTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTT 546

Query: 545 QYRH--DGACPTTTFSELLNAIHNGI-YNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSS 601
                 +    +TT SE       G+   +     S    VS +G+ T   S+    + S
Sbjct: 547 VSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST----EGS 602

Query: 602 GHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENN 661
           G      A S +   S A +  TT +   S ++ +          S +S     A +E +
Sbjct: 603 GTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS 662

Query: 662 QT 663
           +T
Sbjct: 663 ET 664



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 82/426 (19%), Positives = 159/426 (37%), Gaps = 39/426 (9%)

Query: 256  VPSLTVTTEKTYTSTSNNS--ISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGS 313
            +P+ T  +E T T+++  S   + S +  E TTA   +    E +  T+ G + + T  +
Sbjct: 854  IPASTAGSETTTTTSTEGSETTTASTEGSETTTA---STESSETTTATTIGSETT-TAST 909

Query: 314  EGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSVQ---- 369
            EG    +++    +       G    T  +  S     S  G+  +  S+ GS +     
Sbjct: 910  EGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVST 969

Query: 370  --------SPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGES----GSQEGGVNSFSTL 417
                    S +   + T + + +++ + S   S T  V    S     S EG   +  + 
Sbjct: 970  TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1029

Query: 418  IGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHG 477
             G  +T+  T+  ++   S      +++ TAG +         ET           +   
Sbjct: 1030 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1089

Query: 478  PGRPKGNKNQENVSHLSVSSASPTSSVASAAGSITSS---SLQKSPTLLRNGS------- 527
             G      +  ++   +VS++   ++ AS AGS T++   +  K+ T    GS       
Sbjct: 1090 TGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVST 1149

Query: 528  LQSLSVGSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGS 587
              S +  +S  GSE++  +       TTT S +          ++  A S     S  GS
Sbjct: 1150 TSSETTTASTTGSEMTTVF--TTVSETTTVSTI-----GSEATTSSAAGSEATTTSTEGS 1202

Query: 588  STPVSSSHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRS 647
             T  +S+   + ++         + S   S      TT + T + SS     +  +   S
Sbjct: 1203 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1262

Query: 648  NSSMAA 653
             +++A+
Sbjct: 1263 ETTIAS 1268



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 85/470 (18%), Positives = 165/470 (35%), Gaps = 25/470 (5%)

Query: 260 TVTTEKTYTSTSNNSISGSLKRLEDTTARFTNANFQEVSAHTSSGKDVSETRGSE----- 314
           T ++E T TST+ +  +       +TT  +T  +    ++ T S      T GSE     
Sbjct: 150 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPS 209

Query: 315 --GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSG-----SS 367
             G    + + +  +       G    T  +A S     S  G+  +  S++G     S+
Sbjct: 210 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 269

Query: 368 VQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVT 427
             S     S  DS+        S+ ++A+    +  + S  G   + ++ +G  +T A T
Sbjct: 270 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMAST 329

Query: 428 SQPKSFENSPGDLGNSSLPTAGYK--RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNK 485
             P++ + S      +++  AG +  RA T G E  TV     +    S  G      + 
Sbjct: 330 IGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 389

Query: 486 NQENVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQ 545
                +  S   +  T++    + + T S+     T +      S +  +   GSE++  
Sbjct: 390 TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTV--SITDSETTTTCTEGSEMT-- 445

Query: 546 YRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                A  TT F     +           + S     S  GS T   ++   +  + +  
Sbjct: 446 -----AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTT 500

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQ 665
                + S        V T  ++T + S+     + +  + + S M  +  +   N T  
Sbjct: 501 GSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV--SATGSEMTTVSTEGSENTTVS 558

Query: 666 DLGDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQPGNSSLENLPPVAAS 715
             G  +  +   G     + +  S ++++     +    S E     AAS
Sbjct: 559 TTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAS 608



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 79/389 (20%), Positives = 143/389 (36%), Gaps = 24/389 (6%)

Query: 258 SLTVTTEKTYTSTSNNSISGSLKRLEDTTARFT---NANFQEVSAHTSSGKDVSE--TRG 312
           S T+T     + T+  S +GS      TT   T   +    E +A ++ G + ++  T G
Sbjct: 203 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 262

Query: 313 SE----GKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSSV 368
           SE      G +++A S+           +  TT ++ + F + + + T GS + +  S++
Sbjct: 263 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF-ETTAASTTGS-EPTMASTM 320

Query: 369 QSPQDFLSFTDSDLRNDSYSHSQQSSATKDVHKGESGSQEGGVNSFSTLIGLPSTSAVTS 428
            S     S    +    S   +  S  T     G    +   V S +T +    +   T+
Sbjct: 321 GSETTMASTIGPETTKVS---TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 377

Query: 429 QPKSFENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGNKNQE 488
                E S      S   T     A T G E  T   +  +    S  G      +    
Sbjct: 378 SIMGSETSTDSTTGSETTT-----ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 432

Query: 489 NVSHLSVSSASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRH 548
             +  + +  S  ++V++     T++S + S   + + S  S +  +S  GSE +     
Sbjct: 433 ETT-TTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS-DSETTTASTEGSETTTVTTA 490

Query: 549 DGACPT--TTFSELLNAIHNGIYNSNDVAV-SFPNVVSGSGSSTPVSSSHLPQQSSGHLQ 605
                T  TT SE   A + G+  +    + S     S  GS T   S+   + ++   +
Sbjct: 491 GSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTE 550

Query: 606 QVGALSPSAVSSAAPAVATTQANTLSGSS 634
                + S   S    V+TT   T + S+
Sbjct: 551 GSENTTVSTTGSETTTVSTTGLETTTTST 579



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 47/221 (21%), Positives = 87/221 (39%), Gaps = 14/221 (6%)

Query: 417 LIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYKR--AQTSGIEEETVKEKKRKGNKQS 474
           + G  +T+  T+  K    S      +  P AG     A T+G E  T+  K  +    S
Sbjct: 1   MAGSEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTAS 60

Query: 475 KHGPGRPKGNKNQENVSHLSVS-SASPTSSVASAAGSITSSSLQKSPTLLRNGSLQSLSV 533
             G      +      + +S+S S   T+S A +  +  SS+   + T    GS  ++S 
Sbjct: 61  TAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTIST 120

Query: 534 GSSPVGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTPVSS 593
             S   + +S+         T T + +++A+ +    +N    S   V S +GS T   S
Sbjct: 121 AGSET-TTVSI---------TGTETTMVSAMGSET-TTNSTTSSETTVTSTAGSETTTVS 169

Query: 594 SHLPQQSSGHLQQVGALSPSAVSSAAPAVATTQANTLSGSS 634
           +   + ++ +       + S   S    V T  + T++ S+
Sbjct: 170 TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPST 210


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,099,685
Number of Sequences: 37866
Number of extensions: 2255228
Number of successful extensions: 17499
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 705
Number of HSP's that attempted gapping in prelim test: 12508
Number of HSP's gapped (non-prelim): 4339
length of query: 1011
length of database: 18,247,518
effective HSP length: 112
effective length of query: 899
effective length of database: 14,006,526
effective search space: 12591866874
effective search space used: 12591866874
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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