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Search of human proteins with 5729840
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5729840 tubulin, gamma complex associated protein 2 [Homo
sapiens]
(902 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5729840 tubulin, gamma complex associated protein 2 [Homo sap... 1779 0.0
gi|5453660 tubulin, gamma complex associated protein 3 [Homo sap... 206 8e-53
gi|38454194 tubulin, gamma complex associated protein 4 [Homo sa... 98 3e-20
gi|56788364 tubulin, gamma complex associated protein 6 [Homo sa... 77 7e-14
gi|156616299 tubulin, gamma complex associated protein 5 isoform... 52 2e-06
gi|156616297 tubulin, gamma complex associated protein 5 isoform... 52 2e-06
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] 38 0.037
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 38 0.037
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 35 0.41
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 34 0.54
gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens] 34 0.70
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 33 1.2
gi|122937416 hypothetical protein LOC85452 [Homo sapiens] 33 1.6
gi|38044112 restin isoform b [Homo sapiens] 33 1.6
gi|4506751 restin isoform a [Homo sapiens] 33 1.6
gi|38788260 bromodomain PHD finger transcription factor isoform ... 32 2.0
gi|38788274 bromodomain PHD finger transcription factor isoform ... 32 2.0
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 32 2.7
gi|51988900 XPG-complementing protein [Homo sapiens] 32 3.5
gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens] 32 3.5
gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo sapi... 32 3.5
gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo sapi... 32 3.5
gi|42794620 Huntingtin interacting protein E [Homo sapiens] 32 3.5
gi|63054866 leucine rich repeat containing 16A [Homo sapiens] 31 4.5
gi|4758648 kinesin family member 5B [Homo sapiens] 31 4.5
gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3 c... 31 4.5
gi|212276096 leucine rich repeat (in FLII) interacting protein 1... 31 4.5
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 31 4.5
gi|166197690 neuronal guanine nucleotide exchange factor isoform... 31 4.5
gi|166197688 neuronal guanine nucleotide exchange factor isoform... 31 4.5
>gi|5729840 tubulin, gamma complex associated protein 2 [Homo
sapiens]
Length = 902
Score = 1779 bits (4609), Expect = 0.0
Identities = 902/902 (100%), Positives = 902/902 (100%)
Query: 1 MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP 60
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP
Sbjct: 1 MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP 60
Query: 61 EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI 120
EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI
Sbjct: 61 EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI 120
Query: 121 NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW 180
NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW
Sbjct: 121 NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW 180
Query: 181 VYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAG 240
VYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAG
Sbjct: 181 VYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAG 240
Query: 241 RQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLV 300
RQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLV
Sbjct: 241 RQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLV 300
Query: 301 KEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLH 360
KEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLH
Sbjct: 301 KEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLH 360
Query: 361 DRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQ 420
DRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQ
Sbjct: 361 DRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQ 420
Query: 421 EDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLK 480
EDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLK
Sbjct: 421 EDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLK 480
Query: 481 ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELR 540
ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELR
Sbjct: 481 ERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELR 540
Query: 541 KPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAM 600
KPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAM
Sbjct: 541 KPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAM 600
Query: 601 AHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI 660
AHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI
Sbjct: 601 AHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWI 660
Query: 661 SNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNID 720
SNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNID
Sbjct: 661 SNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNID 720
Query: 721 DVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTL 780
DVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTL
Sbjct: 721 DVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTL 780
Query: 781 EHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARL 840
EHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARL
Sbjct: 781 EHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARL 840
Query: 841 SIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVT 900
SIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVT
Sbjct: 841 SIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVT 900
Query: 901 AQ 902
AQ
Sbjct: 901 AQ 902
>gi|5453660 tubulin, gamma complex associated protein 3 [Homo
sapiens]
Length = 907
Score = 206 bits (524), Expect = 8e-53
Identities = 182/713 (25%), Positives = 323/713 (45%), Gaps = 106/713 (14%)
Query: 206 GTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAGRQSRTFLVD--PNLDLSIRELVHRI 263
GT+ + E+A+V D+LYV G+DG+ + + V+ NL S+R+ R+
Sbjct: 241 GTMEIT--EAALVRDILYVFQGIDGKNIKMN----NTENCYKVEGKANLSRSLRDTAVRL 294
Query: 264 LPVAASYSAVTRFIEEKS-SFEYGQVNHALAAAMRTLVKEHL----ILVSQLEQLHRQGL 318
+ ++ + R+ +++S +G V + AA+ ++E+ +L SQL+ QG+
Sbjct: 295 SELGWLHNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGV 354
Query: 319 -------LSLQKL--WFYIQPAMRTMDILASLATSVDKGECL-GGSTLSLLHDRSFSYTG 368
L+L++L W Y P +R L +LA VD + GG S +H +++ TG
Sbjct: 355 NLGLESSLTLRRLLVWTY-DPKIR----LKTLAALVDHCQGRKGGELASAVH--AYTKTG 407
Query: 369 DSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQEDYNDKYW 428
D + L ++ S P L +WIY G + D Y EF V K D+ W
Sbjct: 408 DPYMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVK-------TDRLW 460
Query: 429 DQRYTIVQQQIPSFL-QKMADKILSTGKYLNVVRECGHDVTCPVAKEI------------ 475
+YT+ + IPSF+ + K+L GK +N + + HD T P K I
Sbjct: 461 HDKYTLRKSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQT-PTTKMIAVTKSAESPQDA 519
Query: 476 --IYTLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMD 533
++T E A+ +I+ A+ SK LLD L ++ L+ H+++++RY L+ QGDF H MD
Sbjct: 520 ADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMD 579
Query: 534 LAEEELRKPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIE 593
L + EL +P + L +LE A+R + A D ++LR L +
Sbjct: 580 LLKPELVRPATTLYQHNLTGILETAVRATNAQFDS---------------PEILRRLDVR 624
Query: 594 TKQEKAMAHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVER 653
+ P + +G + FS DY V P++ + R+ ++ Y +F ++ K +E
Sbjct: 625 ------LLEVSPGD---TGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEY 675
Query: 654 QLCSVWISNKTAKQHSLHSAQWFAGAF----TLRQRMLNFVQNIQYYMMFEVMEPTWHIL 709
L + L + F+G L M++F+ +QYY+ FEV+E +W L
Sbjct: 676 ILTDI-RKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDEL 734
Query: 710 EKNLKSASNIDDVLGHHTGFLDTCLKDCMLTNP------ELLKVFSKLMSV----CVMFT 759
++ A ++D ++ H FLDT + C+L + +L VF +++ + ++
Sbjct: 735 WNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFDQIIELQNAQDAIYR 794
Query: 760 NCMQKFTQSMKLDGELGGQTLEHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFE 819
+++ + ++ + + + +E G+ A EE K + E +++ +
Sbjct: 795 AALEELQRRLQFEEKKKQREIEGQ--WGVTAAEEEE-----ENKRIGEFKESIPKMCSQL 847
Query: 820 ATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRLDFNGFYTERLERL 872
+ F + L LL T+ + + + RLDFN Y R RL
Sbjct: 848 RILTHFYQGIVQQFLVLL-------TTSSDESLRFLSFRLDFNEHYKAREPRL 893
>gi|38454194 tubulin, gamma complex associated protein 4 [Homo
sapiens]
Length = 666
Score = 98.2 bits (243), Expect = 3e-20
Identities = 123/624 (19%), Positives = 238/624 (38%), Gaps = 102/624 (16%)
Query: 217 VVEDLLYVLVGVDGRYVSAQPLAGRQ-SRTFLVDPNLDLSIRELVHRILPVAASYSAVTR 275
++ +LL L G G + +G Q S+ F P L S +++R+ + Y T
Sbjct: 1 MIHELLLALSGYPGSIFTWNKRSGLQVSQDF---PFLHPSETSVLNRLCRLGTDYIRFTE 57
Query: 276 FIEEKSSFEYGQVNHALAAAMRTL----VKEHLILVSQLEQLHRQGLLSLQKLW------ 325
FIE+ + Q +H L ++ + + Q +RQ LL L++ +
Sbjct: 58 FIEQYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHL 117
Query: 326 ------FYIQPAMRTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTGDSQAQELCLYL 379
+++ + + + + G L ++ S G + +
Sbjct: 118 SISHVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCG--GLPPVRSALEKI 175
Query: 380 TKAASAPYFEVLEKWIYRGIIHDPYSEFMVEE---------------------------- 411
++ L W+ G++ D + EF +++
Sbjct: 176 LAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQL 235
Query: 412 HELRKERIQEDYND-----KYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHD 466
EL+ R+ E+ N K + R I+ IP ++A+KIL G+ + + +
Sbjct: 236 RELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPV---RVAEKILFVGESVQMFENQNVN 292
Query: 467 VTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDF------------------LMEEKE 508
+T K I +E + ++ + L+DF ++EE +
Sbjct: 293 LT---RKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESD 349
Query: 509 LVAHLRSIKRYFLMDQGDFFVHFMDLAEEELRKPVEDITPPRLEALLELALRMSTANTDP 568
L+ L+ IK ++L+ +G+ F F+D A+ L+ P +T E + +A + S
Sbjct: 350 LLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVT----EHDVNVAFQQSAH---- 401
Query: 569 FKDDLKIDLMPHDLITQLLRVLAIETKQEKAMAHA--------DPTELALSGLEAFSFDY 620
K+ L +L+ L + K+ K A P E SG A Y
Sbjct: 402 -----KVLLDDDNLLPLLHLTIEYHGKEHKDATQAREGPSRETSPREAPASGWAALGLSY 456
Query: 621 IVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAQWFAGAF 680
V+WPL ++ L +Y ++F+++ + V+ +L W K L S Q A +
Sbjct: 457 KVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKH--LKSNQTDAIKW 514
Query: 681 TLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCMLT 740
LR M V N+QYY+ +V+E + L + S + + + H FL L +
Sbjct: 515 RLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFIL 574
Query: 741 NPELLKVFSKLMSVCVMFTNCMQK 764
+ ++++ +C F + + +
Sbjct: 575 LKPVFHCLNEILDLCHSFCSLVSQ 598
>gi|56788364 tubulin, gamma complex associated protein 6 [Homo
sapiens]
Length = 1819
Score = 77.0 bits (188), Expect = 7e-14
Identities = 89/351 (25%), Positives = 154/351 (43%), Gaps = 62/351 (17%)
Query: 209 PLASQESAVVEDLLYVLVGVDGRYVSAQPLAGRQSRTFLVDPNLDLS------IRELVHR 262
P+ +E +V+D+L VL+GV VSA + ++ F+V + +S I L+
Sbjct: 344 PVLVKECELVKDVLNVLIGV----VSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSE 399
Query: 263 ILPVAASYSAVTRFIEEK---SSFEYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLL 319
+ Y+ ++ F + S + G V A + +R ++ + V L L
Sbjct: 400 VAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACV-----LSTPPTL 454
Query: 320 SLQKLWFYIQPAMRTMDILASLAT--SVDKGECLGG---------STLSLLHDRSFSYTG 368
SL + F + R + LA L +V G C GG LS L+ + +
Sbjct: 455 SLLTIGFLFKKLGRQLRYLAELCGVGAVLPGTCGGGPRAAFPTGVKLLSYLYQEAL-HNC 513
Query: 369 DSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVE-EHELRKERIQEDYNDK- 426
++ + L L K + PY + W+Y G+ D Y EFM++ HE + DK
Sbjct: 514 SNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYL------SFRDKL 567
Query: 427 YWDQRYTIVQQQ----IPSFLQKMADKILSTGKYLNVVR-------ECGHDVTCPVAKEI 475
YW Y ++ ++ +P FL+ +A I GK +N+++ C DV P +
Sbjct: 568 YWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGKTINLLKLCCPRHYLCWSDVPVP-RISV 626
Query: 476 IYTLKE--------RAYVEQIEKAFNYA--SKVLLDFLME--EKELVAHLR 514
I++L+E YV ++E+ ++ SK + ME ++EL+AH R
Sbjct: 627 IFSLEELKEIEKDCAVYVGRMERVARHSSVSKEEKELRMEIAKQELIAHAR 677
Score = 68.9 bits (167), Expect = 2e-11
Identities = 62/286 (21%), Positives = 117/286 (40%), Gaps = 27/286 (9%)
Query: 479 LKERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEE 538
L +R+ + + +K +D+ E L AH +++ + LM+ G+F DL E+
Sbjct: 1483 LMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEK 1542
Query: 539 L---RKPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETK 595
L + P E + P L ++L AL+ S P +L LA++
Sbjct: 1543 LGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLS---------------LALKYL 1587
Query: 596 QEKAMAHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQL 655
E +A L Y V WPL+++I L++Y +F + K + L
Sbjct: 1588 PEVFAPNAPDV------LSCLELRYKVDWPLNIVITEGCLSKYSGVFSFLLQLKLMMWAL 1641
Query: 656 CSVWIS-NKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLK 714
V +TA + + F + M +FV+ IQ Y+ +++ TW L
Sbjct: 1642 KDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLA 1701
Query: 715 SASNIDDVLGHHTGFLDTCLKDCMLTN--PELLKVFSKLMSVCVMF 758
+ +++++ H +L + +LT ++ V + S+ + F
Sbjct: 1702 TVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSIFSLVLKF 1747
>gi|156616299 tubulin, gamma complex associated protein 5 isoform b
[Homo sapiens]
Length = 1024
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/327 (18%), Positives = 126/327 (38%), Gaps = 51/327 (15%)
Query: 460 VRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRY 519
V VTC + TL+ Y I+K + L+ L ++ LV +L++++ +
Sbjct: 671 VDRSSESVTCQTFE---LTLRSCLY-PHIDKQYLDCCGNLMQTLKKDYRLVEYLQAMRNF 726
Query: 520 FLMDQGDFFVHFMDLAEEELRKPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMP 579
FLM+ GD F +++R+ L L+ A+ P
Sbjct: 727 FLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQR---------------YP 771
Query: 580 HDLITQLLRVLAIETKQEKAMAHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQ 639
D + ++T ++K H L+ + Y V WP+ ++I+ + Y
Sbjct: 772 EDSSRLSISFENVDTAKKKLPVHI---------LDGLTLSYKVPWPVDIVISLECQKIYN 822
Query: 640 MLFRHMFYCKHVERQLCSVWISNKTA-------KQHSLHS--------------AQWFAG 678
+F + K + L + + K+ +H Q
Sbjct: 823 QVFLLLLQIKWAKYSLDVLLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHR 882
Query: 679 AFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCM 738
F LR ++++FV ++ Y+M ++ T + ++ A ++D ++ H +L T C+
Sbjct: 883 MFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCL 942
Query: 739 LTNPE--LLKVFSKLMSVCVMFTNCMQ 763
L + + K++++ +MF + Q
Sbjct: 943 LREKVSFVKEAIMKVLNLALMFADGWQ 969
Score = 40.4 bits (93), Expect = 0.007
Identities = 53/288 (18%), Positives = 112/288 (38%), Gaps = 62/288 (21%)
Query: 268 ASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLLSLQKLWFY 327
A Y F EE + E +N+ + +V + +SQL+ LH+ + ++
Sbjct: 367 ALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGVAEVPPD 426
Query: 328 IQPAMRTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTGDSQAQELCLYLTKAASAPY 387
+ +R +L +L ++ + + +G ++ Q L L PY
Sbjct: 427 TRNVVRASHLLNTLYKAILEYDNVGEAS--------------EQTVSLLFSLWVETVRPY 472
Query: 388 FEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQEDYNDKYWDQRYTIV------------ 435
+ +++WI G + D EF+++ R + + ++ D +W YT+
Sbjct: 473 LQTVDEWIVHGHLWDGAREFIIQ----RNKNVPVNHRD-FWYATYTLYSVSEKTENEEKM 527
Query: 436 -----------------QQQIPSFLQKMADKILSTGKYLNVVR--ECGHDVTCPVA---- 472
Q + SFL+ + +I+ GK + +++ +C TC
Sbjct: 528 SDNASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDA 587
Query: 473 -KEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEE---KELVAHLRSI 516
++ +YTL ++E ++ + L E+ KE + ++SI
Sbjct: 588 ERKSLYTL----FLESVQSRLRHGEDSTPQVLTEQQATKENLMKMQSI 631
>gi|156616297 tubulin, gamma complex associated protein 5 isoform a
[Homo sapiens]
Length = 1024
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/327 (18%), Positives = 126/327 (38%), Gaps = 51/327 (15%)
Query: 460 VRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRY 519
V VTC + TL+ Y I+K + L+ L ++ LV +L++++ +
Sbjct: 671 VDRSSESVTCQTFE---LTLRSCLY-PHIDKQYLDCCGNLMQTLKKDYRLVEYLQAMRNF 726
Query: 520 FLMDQGDFFVHFMDLAEEELRKPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMP 579
FLM+ GD F +++R+ L L+ A+ P
Sbjct: 727 FLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQR---------------YP 771
Query: 580 HDLITQLLRVLAIETKQEKAMAHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQ 639
D + ++T ++K H L+ + Y V WP+ ++I+ + Y
Sbjct: 772 EDSSRLSISFENVDTAKKKLPVHI---------LDGLTLSYKVPWPVDIVISLECQKIYN 822
Query: 640 MLFRHMFYCKHVERQLCSVWISNKTA-------KQHSLHS--------------AQWFAG 678
+F + K + L + + K+ +H Q
Sbjct: 823 QVFLLLLQIKWAKYSLDVLLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHR 882
Query: 679 AFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCM 738
F LR ++++FV ++ Y+M ++ T + ++ A ++D ++ H +L T C+
Sbjct: 883 MFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCL 942
Query: 739 LTNPE--LLKVFSKLMSVCVMFTNCMQ 763
L + + K++++ +MF + Q
Sbjct: 943 LREKVSFVKEAIMKVLNLALMFADGWQ 969
Score = 40.4 bits (93), Expect = 0.007
Identities = 53/288 (18%), Positives = 112/288 (38%), Gaps = 62/288 (21%)
Query: 268 ASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLLSLQKLWFY 327
A Y F EE + E +N+ + +V + +SQL+ LH+ + ++
Sbjct: 367 ALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGVAEVPPD 426
Query: 328 IQPAMRTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTGDSQAQELCLYLTKAASAPY 387
+ +R +L +L ++ + + +G ++ Q L L PY
Sbjct: 427 TRNVVRASHLLNTLYKAILEYDNVGEAS--------------EQTVSLLFSLWVETVRPY 472
Query: 388 FEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQEDYNDKYWDQRYTIV------------ 435
+ +++WI G + D EF+++ R + + ++ D +W YT+
Sbjct: 473 LQTVDEWIVHGHLWDGAREFIIQ----RNKNVPVNHRD-FWYATYTLYSVSEKTENEEKM 527
Query: 436 -----------------QQQIPSFLQKMADKILSTGKYLNVVR--ECGHDVTCPVA---- 472
Q + SFL+ + +I+ GK + +++ +C TC
Sbjct: 528 SDNASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDA 587
Query: 473 -KEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEE---KELVAHLRSI 516
++ +YTL ++E ++ + L E+ KE + ++SI
Sbjct: 588 ERKSLYTL----FLESVQSRLRHGEDSTPQVLTEQQATKENLMKMQSI 631
>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
Length = 1164
Score = 38.1 bits (87), Expect = 0.037
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 4/146 (2%)
Query: 26 EVYIDLLQKNRTPYVTTTVSAHSAKVKIAE---FSRTPEDFLKKYDELKSKNTRNLDPLV 82
E Y+ + + + ++T +++ V I+ T +DF+ K ++ K N
Sbjct: 482 EFYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLENAVVAD 541
Query: 83 YLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLG 142
+ SK + E L+ L Q ++ A G S + A S S + L E ++QLG
Sbjct: 542 AVASKCSVLNEKLEQLLQALHTDSQAAPVLPGLSPLIVEEDAVESS-SEESLGESKEQLG 600
Query: 143 SVATGSTLQQSLELKRKMLRDKQNKK 168
T + Q++++ + MLR KK
Sbjct: 601 DDVTKPSSQKAVKPREIMLRANSLKK 626
>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
Length = 1220
Score = 38.1 bits (87), Expect = 0.037
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 4/146 (2%)
Query: 26 EVYIDLLQKNRTPYVTTTVSAHSAKVKIAE---FSRTPEDFLKKYDELKSKNTRNLDPLV 82
E Y+ + + + ++T +++ V I+ T +DF+ K ++ K N
Sbjct: 482 EFYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLENAVVAD 541
Query: 83 YLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLG 142
+ SK + E L+ L Q ++ A G S + A S S + L E ++QLG
Sbjct: 542 AVASKCSVLNEKLEQLLQALHTDSQAAPVLPGLSPLIVEEDAVESS-SEESLGESKEQLG 600
Query: 143 SVATGSTLQQSLELKRKMLRDKQNKK 168
T + Q++++ + MLR KK
Sbjct: 601 DDVTKPSSQKAVKPREIMLRANSLKK 626
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 34.7 bits (78), Expect = 0.41
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 17/176 (9%)
Query: 5 RIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVK-IAEFSRTPEDF 63
++ H+ N L + + + E Y LLQKN+ +AH A +K + E ++
Sbjct: 281 KLLHERNASLVMTKAQLTEVQEAYETLLQKNQ----GILSAAHEALLKQVNELRAELKEE 336
Query: 64 LKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAK---ERAELAAAAVGSSTTSI 120
KK LKS+ L+ + L L E +E ++ L++ K + + ++ S+ S
Sbjct: 337 SKKAVSLKSQ----LEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSS 392
Query: 121 NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPI 176
+ P ++++ ++L++ QL L LE KRK+L + +K + L +
Sbjct: 393 SQPHWSNELIAEQLQQQVSQL-----QDQLDAELEDKRKVLLELSREKAQNEDLKL 443
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 34.3 bits (77), Expect = 0.54
Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 8/164 (4%)
Query: 5 RIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFL 64
R+H +V ++ R H D E ++ QK R T S K ++ + E
Sbjct: 903 RLHREVAQV----RQHMAD-LEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALK 957
Query: 65 KKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPA 124
K+ +EL+ + + + + +L D L Q+ K + + AVG + +
Sbjct: 958 KQIEELQQEARKAITEQKQKMRRLGSD---LTSAQKEMKTKHKAYENAVGILSRRLQEAL 1014
Query: 125 AASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKK 168
AA + + EL +LR Q GS + L + ++ L+ + K
Sbjct: 1015 AAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSK 1058
>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
Length = 1720
Score = 33.9 bits (76), Expect = 0.70
Identities = 19/63 (30%), Positives = 33/63 (52%)
Query: 105 RAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDK 164
R L A+ T ++VP +K +++ ++ L+KQL V G LQ+ + + +K
Sbjct: 1249 REILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEK 1308
Query: 165 QNK 167
QNK
Sbjct: 1309 QNK 1311
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
sapiens]
Length = 2346
Score = 33.1 bits (74), Expect = 1.2
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 8/123 (6%)
Query: 16 LLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKY---DELKS 72
L+ H D + + DLL+ N Y S + ++A+ S+ E K D
Sbjct: 1501 LITRHAKDTVKSFEDLLRSNDIDYYL----GQSFREQLAQGSQLTERLTSKLSTKDHKSE 1556
Query: 73 KNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQ 132
K+ L+PL LS+ ++KE + + Q + L ++ + + S P++ S +S
Sbjct: 1557 KDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLS-D 1615
Query: 133 ELE 135
ELE
Sbjct: 1616 ELE 1618
>gi|122937416 hypothetical protein LOC85452 [Homo sapiens]
Length = 762
Score = 32.7 bits (73), Expect = 1.6
Identities = 28/125 (22%), Positives = 52/125 (41%), Gaps = 3/125 (2%)
Query: 54 AEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAV 113
A R E K+ E R +D +V L ++ +++TL+ Q + +AELA V
Sbjct: 258 ASLGRIREQEKKEEMECHEYMRRRMDAVVALKGSISANRDTLRKFQAWDRAKAELAEQRV 317
Query: 114 GSSTTSI---NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNS 170
+ +I A + + +EL Q + L++ + R + + + +K
Sbjct: 318 QAEKKAILAQGRDAFRHLVHQRRRQELEAQKRAFEEEQKLRKQEIISRILKEEAEEEKRK 377
Query: 171 GQHLP 175
QH P
Sbjct: 378 KQHPP 382
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 32.7 bits (73), Expect = 1.6
Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 28/164 (17%)
Query: 17 LRVHGGDGAEVYIDLLQKNRTP-YVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNT 75
LR+ D E+ + L + N ++ ++ + K + ++ ++ KK++E K +
Sbjct: 905 LRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAE-----QSQQEAAKKHEEEKKELE 959
Query: 76 RNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI-------------NV 122
R L S L + ET Q K R E A + + I +
Sbjct: 960 RKL-------SDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKL 1012
Query: 123 PAAASKIS--MQELEELRKQLGSVATGSTLQQSLELKRKMLRDK 164
A + S +QELEELRKQ T + ++++ +M ++K
Sbjct: 1013 KGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1056
Score = 30.4 bits (67), Expect = 7.8
Identities = 25/99 (25%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 66 KYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKE----RAELAAAAVGSSTTSIN 121
K D+L++ V LL++L E+K ++ LQ +E + +L A V + +
Sbjct: 409 KMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIME 468
Query: 122 VPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKM 160
+ + + +QE+ ELR++L S + SL L +++
Sbjct: 469 LEKDLA-LRVQEVAELRRRLESNKPAGDVDMSLSLLQEI 506
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 32.7 bits (73), Expect = 1.6
Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 28/164 (17%)
Query: 17 LRVHGGDGAEVYIDLLQKNRTP-YVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNT 75
LR+ D E+ + L + N ++ ++ + K + ++ ++ KK++E K +
Sbjct: 940 LRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAE-----QSQQEAAKKHEEEKKELE 994
Query: 76 RNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI-------------NV 122
R L S L + ET Q K R E A + + I +
Sbjct: 995 RKL-------SDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKL 1047
Query: 123 PAAASKIS--MQELEELRKQLGSVATGSTLQQSLELKRKMLRDK 164
A + S +QELEELRKQ T + ++++ +M ++K
Sbjct: 1048 KGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1091
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 91 DKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTL 150
+KE Q ++Q AK+R E V +++T+ + S IS + + GSV TG+ +
Sbjct: 2031 EKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKM 2090
Query: 151 QQSLELKRKMLRDKQNKKNSGQHLPIFPAWV 181
+ ++ Q KN Q F WV
Sbjct: 2091 VLTTKVGSPATVTFQQNKNFHQ---TFATWV 2118
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 91 DKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTL 150
+KE Q ++Q AK+R E V +++T+ + S IS + + GSV TG+ +
Sbjct: 1905 EKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKM 1964
Query: 151 QQSLELKRKMLRDKQNKKNSGQHLPIFPAWV 181
+ ++ Q KN Q F WV
Sbjct: 1965 VLTTKVGSPATVTFQQNKNFHQ---TFATWV 1992
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 32.0 bits (71), Expect = 2.7
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 17/151 (11%)
Query: 29 IDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKL 88
+D L++ + + T A ++I+E +R ED K+ + S+ ++ + L K
Sbjct: 420 LDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQQS-EALKEEAEKR 478
Query: 89 TED-----KETLQY--LQQNAKERAELAAAAVGSSTTSINVPAAASK--------ISMQE 133
ED +E+++ L+ ERA + T N K ++Q+
Sbjct: 479 REDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQ 538
Query: 134 LEELRKQLGSVATGSTLQ-QSLELKRKMLRD 163
+E LRK+L V T LQ + L K + LRD
Sbjct: 539 IENLRKELNDVLTKRALQEEELHSKEEKLRD 569
>gi|51988900 XPG-complementing protein [Homo sapiens]
Length = 1186
Score = 31.6 bits (70), Expect = 3.5
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 10/123 (8%)
Query: 57 SRTPEDFLKKYDELKSKNTR-NLDPLVYLLSKLTEDKETLQYLQQNAKE----RAELAAA 111
++T E +L ++ T+ +D L + ED + ++ + N R E AA
Sbjct: 971 TKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAA 1030
Query: 112 AVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSG 171
A + I + A + + L++ +++ +TL++S LKRK L D + K G
Sbjct: 1031 A-----SEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEESSSLKRKRLSDSKRKNTCG 1085
Query: 172 QHL 174
L
Sbjct: 1086 GFL 1088
>gi|17511435 roundabout homolog 4, magic roundabout [Homo sapiens]
Length = 1007
Score = 31.6 bits (70), Expect = 3.5
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 8/96 (8%)
Query: 803 KHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRL--- 859
KH +H+D+ L + +T D + S+ L L DC + S SR
Sbjct: 514 KHRMDHSDSQWLADTWRSTSGSRDLSSSSSLSSRLGA-DARDPLDCRRSLLSWDSRSPGV 572
Query: 860 ----DFNGFYTERLERLSAERSQKATPQVPVLRGPP 891
D + FY + L + + +PQVP +R P
Sbjct: 573 PLLPDTSTFYGSLIAELPSSTPARPSPQVPAVRRLP 608
>gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo
sapiens]
Length = 497
Score = 31.6 bits (70), Expect = 3.5
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 14/129 (10%)
Query: 9 DVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPE---DFLK 65
D+ L L+ G E +++ K R T++ + K+++ E ++ P+ D K
Sbjct: 249 DLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFK 308
Query: 66 KYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAK-----------ERAELAAAAVG 114
+ K NT NL + + +L E + NAK E A AA
Sbjct: 309 SVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQLETAVGAAIKSF 368
Query: 115 SSTTSINVP 123
++ INVP
Sbjct: 369 ENSLGINVP 377
>gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo
sapiens]
Length = 508
Score = 31.6 bits (70), Expect = 3.5
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 14/129 (10%)
Query: 9 DVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPE---DFLK 65
D+ L L+ G E +++ K R T++ + K+++ E ++ P+ D K
Sbjct: 260 DLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFK 319
Query: 66 KYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAK-----------ERAELAAAAVG 114
+ K NT NL + + +L E + NAK E A AA
Sbjct: 320 SVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQLETAVGAAIKSF 379
Query: 115 SSTTSINVP 123
++ INVP
Sbjct: 380 ENSLGINVP 388
>gi|42794620 Huntingtin interacting protein E [Homo sapiens]
Length = 458
Score = 31.6 bits (70), Expect = 3.5
Identities = 18/71 (25%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Query: 97 YLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLEL 156
YL ++ +RA+ AA S +T +++ + + + + + + G + + L Q+LE+
Sbjct: 59 YLLRSKPDRAQHAATKCTSPSTELSITSRGATLLVAKTKA--SPAGKLEARAALNQALEM 116
Query: 157 KRKMLRDKQNK 167
KR+ R+K K
Sbjct: 117 KRQGKREKAQK 127
>gi|63054866 leucine rich repeat containing 16A [Homo sapiens]
Length = 1326
Score = 31.2 bits (69), Expect = 4.5
Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 70 LKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKI 129
LK+ + D L + + L + ET +YLQ+ A + + +STT + K+
Sbjct: 643 LKTNPEKTEDALQKIENYLLRNHETRKYLQEQAYRLQQ----GIVTSTTQQMIDRICVKV 698
Query: 130 SMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKK 168
L LR G +Q+ L+ +++RD +N K
Sbjct: 699 Q-DHLNSLRN-----CGGDAIQEDLKSAERLMRDAKNSK 731
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 31.2 bits (69), Expect = 4.5
Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 16/123 (13%)
Query: 59 TPEDFLKKYDELKSKNTRNLDPLVYLLSKLT--EDKETLQYLQQNAKERAELAAAAVGSS 116
T E + KKY++ K KN + + +L ++L + ET+ +Q KE+A L A V
Sbjct: 336 TAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKD 395
Query: 117 TTSIN-VPAAASKI-----------SMQELEELRKQLGSVATGSTLQQSL--ELKRKMLR 162
T N PA A + +E+ +L KQL Q L +LK +ML
Sbjct: 396 ITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLD 455
Query: 163 DKQ 165
++
Sbjct: 456 QEE 458
>gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3
component n-recognin 5 isoform 2 [Homo sapiens]
Length = 2277
Score = 31.2 bits (69), Expect = 4.5
Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 29/145 (20%)
Query: 86 SKLTEDKETLQYLQQN--AKERAELAAAAVGSSTTSINVPA----AASKISMQELEELRK 139
+K T+++E + ++N A+ + + A A S S N P ++S S++ E +R+
Sbjct: 430 NKETKEEEEAERSERNTFAERLSAVEAIANAISVVSSNGPGNRAGSSSSRSLRLREMMRR 489
Query: 140 QLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFP-----AWVYERPALIGDFLIG 194
L + G R + +S P+ P +WV + PA+ D G
Sbjct: 490 SLRAAGLG--------------RHEAGASSSDHQDPVSPPIAPPSWVPDPPAMDPDAATG 535
Query: 195 AGISTDTALPIGTLPLASQESAVVE 219
G T+ T+P S E +VVE
Sbjct: 536 TGQGPSTS----TIPGPSTEPSVVE 556
>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
isoform 3 [Homo sapiens]
Length = 808
Score = 31.2 bits (69), Expect = 4.5
Identities = 31/141 (21%), Positives = 62/141 (43%), Gaps = 17/141 (12%)
Query: 46 AHSAKVKIAEFSRTP-EDFLKKYDELKSKNTRNLDPLVYLL-----SKLTEDKETLQYLQ 99
A + ++++ E R E+ ++Y +NT D + S E++ + +
Sbjct: 35 AEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTE 94
Query: 100 QNAKERAELAAAAV----------GSSTTSINVPAAASKISMQELEELRKQLGSVATGST 149
+ ++ L+AA + GS TSI++ AS ++EL EL+ Q+ V G
Sbjct: 95 KGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDV-EGKY 153
Query: 150 LQQSLELKRKMLRDKQNKKNS 170
+Q E+K + ++ K +
Sbjct: 154 MQGLKEMKDSLAEVEEKYKKA 174
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 31.2 bits (69), Expect = 4.5
Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 11/95 (11%)
Query: 86 SKLTEDKETLQYLQQNAKERAELAAAAV----------GSSTTSINVPAAASKISMQELE 135
S + E++ + ++ ++ L+AA + GS TSI++ AS ++EL
Sbjct: 209 SPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELN 268
Query: 136 ELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNS 170
EL+ Q+ V G +Q E+K + ++ K +
Sbjct: 269 ELKDQIQDV-EGKYMQGLKEMKDSLAEVEEKYKKA 302
Score = 30.4 bits (67), Expect = 7.8
Identities = 30/122 (24%), Positives = 57/122 (46%), Gaps = 11/122 (9%)
Query: 49 AKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAK-ERAE 107
A V A+ +F+ + D LK D L+ L +L E + QY ++N + ER +
Sbjct: 302 AMVSNAQLDNEKTNFMYQVDTLK-------DMLLELEEQLAESRR--QYEEKNKEFEREK 352
Query: 108 LAAAAVGSSTTSINVPAAASKISMQELEELR-KQLGSVATGSTLQQSLELKRKMLRDKQN 166
A + + + + ++E+ +L+ KQ S+ S LQ+++E K K + +
Sbjct: 353 HAHSILQFQFAEVKEALKQREEMLEEIRQLQQKQASSIREISDLQETIEWKDKKIGALER 412
Query: 167 KK 168
+K
Sbjct: 413 QK 414
>gi|166197690 neuronal guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 618
Score = 31.2 bits (69), Expect = 4.5
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 12/123 (9%)
Query: 53 IAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAA 112
+A+ T + L+ + + + RNL + LL + DK TLQ ++ ++ AE+
Sbjct: 54 LADSPTTLTEALRMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIEDNT 113
Query: 113 VGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQ 172
GS PA+ +E EE ++ S TL Q +L + ++ N Q
Sbjct: 114 NGS-------PASEDTPEEEEEEEEEEEPASPPERKTLPQIC-----LLSNPHSRFNLWQ 161
Query: 173 HLP 175
LP
Sbjct: 162 DLP 164
>gi|166197688 neuronal guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 710
Score = 31.2 bits (69), Expect = 4.5
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 12/123 (9%)
Query: 53 IAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAA 112
+A+ T + L+ + + + RNL + LL + DK TLQ ++ ++ AE+
Sbjct: 146 LADSPTTLTEALRMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIEDNT 205
Query: 113 VGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQ 172
GS PA+ +E EE ++ S TL Q +L + ++ N Q
Sbjct: 206 NGS-------PASEDTPEEEEEEEEEEEPASPPERKTLPQIC-----LLSNPHSRFNLWQ 253
Query: 173 HLP 175
LP
Sbjct: 254 DLP 256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,165,705
Number of Sequences: 37866
Number of extensions: 1321261
Number of successful extensions: 4463
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 4414
Number of HSP's gapped (non-prelim): 68
length of query: 902
length of database: 18,247,518
effective HSP length: 111
effective length of query: 791
effective length of database: 14,044,392
effective search space: 11109114072
effective search space used: 11109114072
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.