Guide to the Human Genome
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Search of human proteins with 57232759

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|57232759 intestine-specific homeobox [Homo sapiens]
         (245 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|57232759 intestine-specific homeobox [Homo sapiens]                517   e-147
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...   109   2e-24
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                 105   3e-23
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap...   105   4e-23
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                100   2e-21
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                 99   3e-21
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                  99   3e-21
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                  99   3e-21
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                  99   3e-21
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                  99   3e-21
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                   99   3e-21
gi|24497589 aristaless related homeobox [Homo sapiens]                 97   1e-20
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]      97   1e-20
gi|7706659 paired related homeobox 2 [Homo sapiens]                    97   1e-20
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                       94   8e-20
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                       94   1e-19
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                     94   1e-19
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          93   2e-19
gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]          93   2e-19
gi|189083681 paired box gene 6 isoform a [Homo sapiens]                93   2e-19
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                  93   2e-19
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                  93   2e-19
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]             92   5e-19
gi|46249382 paired-like homeobox 2a [Homo sapiens]                     92   5e-19
gi|14149760 orthopedia homeobox [Homo sapiens]                         92   5e-19
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     91   7e-19
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]    91   9e-19
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi...    91   9e-19
gi|122937484 dorsal root ganglia homeobox [Homo sapiens]               91   1e-18
gi|34365783 visual system homeobox 2 [Homo sapiens]                    89   3e-18

>gi|57232759 intestine-specific homeobox [Homo sapiens]
          Length = 245

 Score =  517 bits (1331), Expect = e-147
 Identities = 245/245 (100%), Positives = 245/245 (100%)

Query: 1   MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA 60
           MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA
Sbjct: 1   MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA 60

Query: 61  AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN 120
           AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN
Sbjct: 61  AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN 120

Query: 121 LPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP 180
           LPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP
Sbjct: 121 LPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP 180

Query: 181 PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSI 240
           PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSI
Sbjct: 181 PTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSI 240

Query: 241 CATST 245
           CATST
Sbjct: 241 CATST 245


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score =  109 bits (272), Expect = 2e-24
 Identities = 49/95 (51%), Positives = 65/95 (68%)

Query: 49  PEGPGEEGPGEAAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPD 108
           P+ PGE  P      G    +    + ++ +K  RR RTTFTT QLHELE+ F  +HYPD
Sbjct: 103 PKEPGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPD 162

Query: 109 VHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKI 143
           V+ R +LA ++NLPE RVQ+WFQN+RAKWR+QEK+
Sbjct: 163 VYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKL 197


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score =  105 bits (263), Expect = 3e-23
 Identities = 76/212 (35%), Positives = 99/212 (46%), Gaps = 36/212 (16%)

Query: 19  GCCEAPKKLSL-----SFSIEAILKRP--ARRSDMDRPEGP------------------G 53
           G C+ P   SL     S    A L+ P  A+ S +  PE P                  G
Sbjct: 127 GACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAG 186

Query: 54  EEGPGEAAASGSGLEKPPKDQPQEGRKSK-RRVRTTFTTEQLHELEKIFHFTHYPDVHIR 112
            +GP + A+S   L  P +    E  K K RR RTTFT+ QL ELEK+F  THYPDV+ R
Sbjct: 187 VKGPQDRASSD--LPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAR 244

Query: 113 SQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALP------TNLDVA 166
            QLA R +L EARVQ+WFQN+RAKWRK+E+ G +   +     +  LP          + 
Sbjct: 245 EQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQ 304

Query: 167 GPTWTSTALRRLAPPTSCCPSAQDQLASAWFP 198
            P+W        A P   C    D + +   P
Sbjct: 305 NPSWLGN--NGAASPVPACVVPCDPVPACMSP 334


>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
           sapiens]
          Length = 184

 Score =  105 bits (262), Expect = 4e-23
 Identities = 57/108 (52%), Positives = 76/108 (70%), Gaps = 9/108 (8%)

Query: 57  PGEAAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLA 116
           PGE  A+  G   P ++ P   +K  RR RTTFTT QLH+LE+ F  +HYPDV+ R +LA
Sbjct: 5   PGEGPATEGGGLGPGEEAP---KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELA 61

Query: 117 ARINLPEARVQIWFQNQRAKWRKQEKI----GNLGAPQQLSEASVALP 160
           A+++LPE RVQ+WFQN+RAKWR+QE++    G + AP +L EA  ALP
Sbjct: 62  AKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAP-RLPEAP-ALP 107


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 66/146 (45%), Positives = 81/146 (55%), Gaps = 11/146 (7%)

Query: 6   GPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAAS-- 63
           GPAL  G      G  EA +K S + S    L    R    D P    +  PG   AS  
Sbjct: 78  GPALNGGHFYE--GPAEAEEKTSKAASFPQ-LPLDCRGGPRDGPSNL-QGSPGPCLASLH 133

Query: 64  ---GSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARIN 120
                GL  P   +  + +  KRR RTTF+T QL ELEK+F  THYPDV+ R QLA R +
Sbjct: 134 LPLSPGL--PDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTD 191

Query: 121 LPEARVQIWFQNQRAKWRKQEKIGNL 146
           L EARVQ+WFQN+RAKWRK+E+ G +
Sbjct: 192 LTEARVQVWFQNRRAKWRKRERYGKI 217


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 69/200 (34%), Positives = 93/200 (46%), Gaps = 30/200 (15%)

Query: 38  KRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEG-----------RKSKRRVR 86
           K     +D++R E    E   + +  G   E+    Q  EG           ++ +RR R
Sbjct: 163 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 222

Query: 87  TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL 146
           TTFT EQL ELE+ F  THYPD++ R +LA R  L EARVQ+WF N+RA+WRKQ     L
Sbjct: 223 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQL 282

Query: 147 GAPQQLSEASVALPTNLDVAGPTWTSTALRRLA-PPTSCCPSAQDQLASAWFPAWITLLP 205
            A   L       PT    A PT  +  L   +  PTS   +  D  ++   P       
Sbjct: 283 MAFNHLIPGGFP-PT----AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRP------- 330

Query: 206 AHPWETQPVPGLPIHQTCIP 225
                 QP+P   +HQ+ IP
Sbjct: 331 ------QPLPPSTVHQSTIP 344


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 69/200 (34%), Positives = 93/200 (46%), Gaps = 30/200 (15%)

Query: 38  KRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEG-----------RKSKRRVR 86
           K     +D++R E    E   + +  G   E+    Q  EG           ++ +RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223

Query: 87  TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL 146
           TTFT EQL ELE+ F  THYPD++ R +LA R  L EARVQ+WF N+RA+WRKQ     L
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQL 283

Query: 147 GAPQQLSEASVALPTNLDVAGPTWTSTALRRLA-PPTSCCPSAQDQLASAWFPAWITLLP 205
            A   L       PT    A PT  +  L   +  PTS   +  D  ++   P       
Sbjct: 284 MAFNHLIPGGFP-PT----AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRP------- 331

Query: 206 AHPWETQPVPGLPIHQTCIP 225
                 QP+P   +HQ+ IP
Sbjct: 332 ------QPLPPSTVHQSTIP 345


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 69/200 (34%), Positives = 93/200 (46%), Gaps = 30/200 (15%)

Query: 38  KRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEG-----------RKSKRRVR 86
           K     +D++R E    E   + +  G   E+    Q  EG           ++ +RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223

Query: 87  TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL 146
           TTFT EQL ELE+ F  THYPD++ R +LA R  L EARVQ+WF N+RA+WRKQ     L
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQL 283

Query: 147 GAPQQLSEASVALPTNLDVAGPTWTSTALRRLA-PPTSCCPSAQDQLASAWFPAWITLLP 205
            A   L       PT    A PT  +  L   +  PTS   +  D  ++   P       
Sbjct: 284 MAFNHLIPGGFP-PT----AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRP------- 331

Query: 206 AHPWETQPVPGLPIHQTCIP 225
                 QP+P   +HQ+ IP
Sbjct: 332 ------QPLPPSTVHQSTIP 345


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 69/200 (34%), Positives = 93/200 (46%), Gaps = 30/200 (15%)

Query: 38  KRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEG-----------RKSKRRVR 86
           K     +D++R E    E   + +  G   E+    Q  EG           ++ +RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223

Query: 87  TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL 146
           TTFT EQL ELE+ F  THYPD++ R +LA R  L EARVQ+WF N+RA+WRKQ     L
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQL 283

Query: 147 GAPQQLSEASVALPTNLDVAGPTWTSTALRRLA-PPTSCCPSAQDQLASAWFPAWITLLP 205
            A   L       PT    A PT  +  L   +  PTS   +  D  ++   P       
Sbjct: 284 MAFNHLIPGGFP-PT----AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRP------- 331

Query: 206 AHPWETQPVPGLPIHQTCIP 225
                 QP+P   +HQ+ IP
Sbjct: 332 ------QPLPPSTVHQSTIP 345


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 69/200 (34%), Positives = 93/200 (46%), Gaps = 30/200 (15%)

Query: 38  KRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEG-----------RKSKRRVR 86
           K     +D++R E    E   + +  G   E+    Q  EG           ++ +RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223

Query: 87  TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL 146
           TTFT EQL ELE+ F  THYPD++ R +LA R  L EARVQ+WF N+RA+WRKQ     L
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQL 283

Query: 147 GAPQQLSEASVALPTNLDVAGPTWTSTALRRLA-PPTSCCPSAQDQLASAWFPAWITLLP 205
            A   L       PT    A PT  +  L   +  PTS   +  D  ++   P       
Sbjct: 284 MAFNHLIPGGFP-PT----AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRP------- 331

Query: 206 AHPWETQPVPGLPIHQTCIP 225
                 QP+P   +HQ+ IP
Sbjct: 332 ------QPLPPSTVHQSTIP 345


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 69/200 (34%), Positives = 93/200 (46%), Gaps = 30/200 (15%)

Query: 38  KRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEG-----------RKSKRRVR 86
           K     +D++R E    E   + +  G   E+    Q  EG           ++ +RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223

Query: 87  TTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL 146
           TTFT EQL ELE+ F  THYPD++ R +LA R  L EARVQ+WF N+RA+WRKQ     L
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQL 283

Query: 147 GAPQQLSEASVALPTNLDVAGPTWTSTALRRLA-PPTSCCPSAQDQLASAWFPAWITLLP 205
            A   L       PT    A PT  +  L   +  PTS   +  D  ++   P       
Sbjct: 284 MAFNHLIPGGFP-PT----AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRP------- 331

Query: 206 AHPWETQPVPGLPIHQTCIP 225
                 QP+P   +HQ+ IP
Sbjct: 332 ------QPLPPSTVHQSTIP 345


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 61/140 (43%), Positives = 75/140 (53%), Gaps = 17/140 (12%)

Query: 79  RKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWR 138
           ++ +RR RTTFT+ QL ELE+ F  THYPDV  R +LA R++L EARVQ+WFQN+RAKWR
Sbjct: 325 KRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWR 384

Query: 139 KQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAP--PTSCCPSAQDQLASAW 196
           K+EK G           +   P  L   GP    +A   L+P    S  P     L SAW
Sbjct: 385 KREKAG-----------AQTHPPGLPFPGPL---SATHPLSPYLDASPFPPHHPALDSAW 430

Query: 197 FPAWITLLPAHPWETQPVPG 216
             A      A P    P PG
Sbjct: 431 TAAAAAAAAAFP-SLPPPPG 449


>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
          Length = 326

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 44/65 (67%), Positives = 53/65 (81%)

Query: 82  KRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQE 141
           KRR RTTFT+ QL ELEK+F  THYPDV++R QLA R  L EARVQ+WFQN+RAKWRK+E
Sbjct: 132 KRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRE 191

Query: 142 KIGNL 146
           + G +
Sbjct: 192 RYGQI 196


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 61/187 (32%), Positives = 91/187 (48%), Gaps = 25/187 (13%)

Query: 20  CCEAPKKLSLSFSIEA--------ILKRPARRSDMDRPEGPGEEGPG-----EAAASGSG 66
           C +A K  S+S  ++         +  RP  R++    EG   E  G     EAA     
Sbjct: 31  CAQARKNFSVSHLLDLEEVAAAGRLAARPGARAEAR--EGAAREPSGGSSGSEAAPQDGE 88

Query: 67  LEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARV 126
              P +    + +K +RR RTTF + QL  LE++F  THYPD  +R +LA R+NL EARV
Sbjct: 89  CPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARV 148

Query: 127 QIWFQNQRAKWRKQEK----------IGNLGAPQQLSEASVALPTNLDVAGPTWTSTALR 176
           Q+WFQN+RAK+R+ E+          + +      + +     PT L     +WT+++  
Sbjct: 149 QVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYLSWTASSPY 208

Query: 177 RLAPPTS 183
              PP S
Sbjct: 209 STVPPYS 215


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 55/136 (40%), Positives = 71/136 (52%), Gaps = 14/136 (10%)

Query: 24  PKKLSLSFSIEAILKRPARRSDMDRPEGPGEE-----------GPGEAAASGSGLEKPPK 72
           P   S+S  +     +     + D+ E  GE+             G     GS +E  P 
Sbjct: 149 PSVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEP- 207

Query: 73  DQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQN 132
           D P   ++ +RR RTTFT EQL ELEK F  THYPD++ R +LA R  L EARVQ+WF N
Sbjct: 208 DLPL--KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSN 265

Query: 133 QRAKWRKQEKIGNLGA 148
           +RA+WRKQ     L A
Sbjct: 266 RRARWRKQAGANQLAA 281


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 57/144 (39%), Positives = 74/144 (51%), Gaps = 18/144 (12%)

Query: 20  CCEAPKKLSLSFSIEAILK----RPARRSDMDRPEGPGEE-----------GPGEAAASG 64
           C  +     L  SI  +L+    +     + D+ E  GE+             G     G
Sbjct: 143 CDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEG 202

Query: 65  SGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEA 124
           S +E  P D P   ++ +RR RTTFT EQL ELEK F  THYPD++ R +LA R  L EA
Sbjct: 203 SDVESEP-DLPL--KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEA 259

Query: 125 RVQIWFQNQRAKWRKQEKIGNLGA 148
           RVQ+WF N+RA+WRKQ     L A
Sbjct: 260 RVQVWFSNRRARWRKQAGANQLAA 283


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 57/144 (39%), Positives = 74/144 (51%), Gaps = 18/144 (12%)

Query: 20  CCEAPKKLSLSFSIEAILK----RPARRSDMDRPEGPGEE-----------GPGEAAASG 64
           C  +     L  SI  +L+    +     + D+ E  GE+             G     G
Sbjct: 143 CDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEG 202

Query: 65  SGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEA 124
           S +E  P D P   ++ +RR RTTFT EQL ELEK F  THYPD++ R +LA R  L EA
Sbjct: 203 SDVESEP-DLPL--KRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEA 259

Query: 125 RVQIWFQNQRAKWRKQEKIGNLGA 148
           RVQ+WF N+RA+WRKQ     L A
Sbjct: 260 RVQVWFSNRRARWRKQAGANQLAA 283


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 75/197 (38%), Positives = 98/197 (49%), Gaps = 16/197 (8%)

Query: 38  KRPARRSDM---DRPEGPGEEGPGEAAASGSGLEKPPKDQPQEGRKS--KRRVRTTFTTE 92
           + P R  DM   +R   PG     E +      ++  K    EG+    +RR RT FT E
Sbjct: 91  RSPVRELDMGAAERSREPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLE 150

Query: 93  QLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQE----KIGNLGA 148
           QL+ELE++F  THYPD  +R +L+ R+ L EARVQ+WFQN+RAK RKQE    K   +GA
Sbjct: 151 QLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGA 210

Query: 149 PQQLSEASVALPTNLDVAGPTWTSTALRRLAPPTSCCPSAQDQLASAWFPAWITLLP--- 205
             Q     VA   N+      +   +   +  P S    AQ QL SA   A   L P   
Sbjct: 211 ASQFEACRVAPYVNVGALRMPFQQDSHCNVT-PLSFQVQAQLQLDSAVAHAHHHLHPHLA 269

Query: 206 AH-PWETQPVP--GLPI 219
           AH P+   P P  GLP+
Sbjct: 270 AHAPYMMFPAPPFGLPL 286


>gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
          Length = 365

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 42/71 (59%), Positives = 50/71 (70%)

Query: 72  KDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQ 131
           K  P  G++ KRR RT FT  QL ELEK F   HYPDV+ R  LA +  LPE R+Q+WFQ
Sbjct: 154 KASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQ 213

Query: 132 NQRAKWRKQEK 142
           N+RAKWRK+EK
Sbjct: 214 NRRAKWRKREK 224


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 45/94 (47%), Positives = 64/94 (68%), Gaps = 2/94 (2%)

Query: 54  EEGPGEA--AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHI 111
           +EG GE   + S +G +        + ++  +R RT+FT EQ+  LEK F  THYPDV  
Sbjct: 180 QEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFA 239

Query: 112 RSQLAARINLPEARVQIWFQNQRAKWRKQEKIGN 145
           R +LAA+I+LPEAR+Q+WF N+RAKWR++EK+ N
Sbjct: 240 RERLAAKIDLPEARIQVWFSNRRAKWRREEKLRN 273


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 45/94 (47%), Positives = 64/94 (68%), Gaps = 2/94 (2%)

Query: 54  EEGPGEA--AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHI 111
           +EG GE   + S +G +        + ++  +R RT+FT EQ+  LEK F  THYPDV  
Sbjct: 194 QEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFA 253

Query: 112 RSQLAARINLPEARVQIWFQNQRAKWRKQEKIGN 145
           R +LAA+I+LPEAR+Q+WF N+RAKWR++EK+ N
Sbjct: 254 RERLAAKIDLPEARIQVWFSNRRAKWRREEKLRN 287


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 45/94 (47%), Positives = 64/94 (68%), Gaps = 2/94 (2%)

Query: 54  EEGPGEA--AASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHI 111
           +EG GE   + S +G +        + ++  +R RT+FT EQ+  LEK F  THYPDV  
Sbjct: 180 QEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFA 239

Query: 112 RSQLAARINLPEARVQIWFQNQRAKWRKQEKIGN 145
           R +LAA+I+LPEAR+Q+WF N+RAKWR++EK+ N
Sbjct: 240 RERLAAKIDLPEARIQVWFSNRRAKWRREEKLRN 273


>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 54/133 (40%), Positives = 74/133 (55%), Gaps = 26/133 (19%)

Query: 52  PGEE------GPGEAAASGSGLEKPPKDQ---------PQEGRKSKRRVRTTFTTEQLHE 96
           PGE+       P   A S    +K P  Q          Q+G++ ++R RT FT  QL+E
Sbjct: 59  PGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNE 118

Query: 97  LEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL---------- 146
           LE+ F  THYPD+ +R +LA RI L E+RVQ+WFQN+RAKW+K++K  N+          
Sbjct: 119 LERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPT 178

Query: 147 -GAPQQLSEASVA 158
            G PQ  S A+ A
Sbjct: 179 PGLPQFPSAAAAA 191


>gi|46249382 paired-like homeobox 2a [Homo sapiens]
          Length = 284

 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 40/72 (55%), Positives = 57/72 (79%)

Query: 71  PKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWF 130
           P+      ++ +RR+RTTFT+ QL ELE++F  THYPD++ R +LA +I+L EARVQ+WF
Sbjct: 79  PEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWF 138

Query: 131 QNQRAKWRKQEK 142
           QN+RAK+RKQE+
Sbjct: 139 QNRRAKFRKQER 150


>gi|14149760 orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 54/133 (40%), Positives = 74/133 (55%), Gaps = 26/133 (19%)

Query: 52  PGEE------GPGEAAASGSGLEKPPKDQ---------PQEGRKSKRRVRTTFTTEQLHE 96
           PGE+       P   A S    +K P  Q          Q+G++ ++R RT FT  QL+E
Sbjct: 59  PGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNE 118

Query: 97  LEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNL---------- 146
           LE+ F  THYPD+ +R +LA RI L E+RVQ+WFQN+RAKW+K++K  N+          
Sbjct: 119 LERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPT 178

Query: 147 -GAPQQLSEASVA 158
            G PQ  S A+ A
Sbjct: 179 PGLPQFPSAAAAA 191


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 91.3 bits (225), Expect = 7e-19
 Identities = 39/64 (60%), Positives = 55/64 (85%)

Query: 79  RKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWR 138
           ++ +RR+RTTFT+ QL ELE++F  THYPD++ R +LA +I+L EARVQ+WFQN+RAK+R
Sbjct: 95  KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 154

Query: 139 KQEK 142
           KQE+
Sbjct: 155 KQER 158


>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
          Length = 217

 Score = 90.9 bits (224), Expect = 9e-19
 Identities = 52/133 (39%), Positives = 75/133 (56%), Gaps = 9/133 (6%)

Query: 17  SLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAASG--SGLEKPPKDQ 74
           +L   +A K  S+S  ++  L+           E  GE G     + G  SG + P +D 
Sbjct: 24  NLDTLQAKKNFSVSHLLD--LEEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN 81

Query: 75  PQ-----EGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIW 129
            Q     + ++ +RR RTTF + QL  LE++F  THYPD  +R  LA R+NL EARVQ+W
Sbjct: 82  DQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVW 141

Query: 130 FQNQRAKWRKQEK 142
           FQN+RAK+R+ E+
Sbjct: 142 FQNRRAKFRRNER 154


>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
           sapiens]
          Length = 245

 Score = 90.9 bits (224), Expect = 9e-19
 Identities = 52/133 (39%), Positives = 75/133 (56%), Gaps = 9/133 (6%)

Query: 17  SLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAASG--SGLEKPPKDQ 74
           +L   +A K  S+S  ++  L+           E  GE G     + G  SG + P +D 
Sbjct: 24  NLDTLQAKKNFSVSHLLD--LEEAGDMVAAQADENVGEAGRSLLESPGLTSGSDTPQQDN 81

Query: 75  PQ-----EGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIW 129
            Q     + ++ +RR RTTF + QL  LE++F  THYPD  +R  LA R+NL EARVQ+W
Sbjct: 82  DQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVW 141

Query: 130 FQNQRAKWRKQEK 142
           FQN+RAK+R+ E+
Sbjct: 142 FQNRRAKFRRNER 154


>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
          Length = 268

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 46/93 (49%), Positives = 62/93 (66%), Gaps = 3/93 (3%)

Query: 79  RKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWR 138
           R+ +RR RTTFT +QL  LE +F  THYPDV  R +LA +INL EARVQ+WFQN+RAKWR
Sbjct: 35  RRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWR 94

Query: 139 KQEKIGN---LGAPQQLSEASVALPTNLDVAGP 168
           K E+  +    GA + ++E +     N++   P
Sbjct: 95  KTERGASDQEPGAKEPMAEVTPPPVRNINSPPP 127


>gi|34365783 visual system homeobox 2 [Homo sapiens]
          Length = 361

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 40/67 (59%), Positives = 50/67 (74%)

Query: 76  QEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRA 135
           Q  ++ KRR RT FT+ QL ELEK F+  HYPDV+ R  LA +  LPE R+Q+WFQN+RA
Sbjct: 142 QTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRA 201

Query: 136 KWRKQEK 142
           KWRK+EK
Sbjct: 202 KWRKREK 208


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,242,672
Number of Sequences: 37866
Number of extensions: 637659
Number of successful extensions: 3591
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 294
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 3123
Number of HSP's gapped (non-prelim): 532
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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