Search of human proteins with 56788368

Search of human proteins with 56788368

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56788368 phosphatidylinositol-binding clathrin assembly
protein isoform 2 [Homo sapiens]
         (610 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56788368 phosphatidylinositol-binding clathrin assembly prote...  1208   0.0  
gi|56788366 phosphatidylinositol-binding clathrin assembly prote...  1158   0.0  
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...   504   e-142
gi|91982772 mucin 17 [Homo sapiens]                                    38   0.031
gi|161019170 mucin 5AC [Homo sapiens]                                  37   0.041
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    37   0.041
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       37   0.041
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    37   0.053
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    37   0.053
gi|151301154 mucin 6, gastric [Homo sapiens]                           37   0.053
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    37   0.069
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    37   0.069
gi|13489073 egl nine homolog 1 [Homo sapiens]                          35   0.15 
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap...    35   0.26 
gi|116284392 mucin 2 precursor [Homo sapiens]                          35   0.26 
gi|117190342 PHD finger protein 2 [Homo sapiens]                       35   0.26 
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         35   0.26 
gi|236459851 ubinuclein 2 [Homo sapiens]                               34   0.34 
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            34   0.34 
gi|33188443 microfilament and actin filament cross-linker protei...    34   0.34 
gi|33188445 microfilament and actin filament cross-linker protei...    34   0.34 
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    34   0.34 
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    34   0.34 
gi|7661968 epsin 4 [Homo sapiens]                                      34   0.45 
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide...    34   0.45 
gi|188497758 ubiquitin associated protein 2-like isoform a [Homo...    34   0.45 
gi|188497756 ubiquitin associated protein 2-like isoform b [Homo...    34   0.45 
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             33   0.59 
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    33   0.59 
gi|11641239 hypothetical protein LOC53838 [Homo sapiens]               33   0.59 

>gi|56788368 phosphatidylinositol-binding clathrin assembly protein
           isoform 2 [Homo sapiens]
          Length = 610

 Score = 1208 bits (3126), Expect = 0.0
 Identities = 610/610 (100%), Positives = 610/610 (100%)

Query: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
           MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA
Sbjct: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60

Query: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
           DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM
Sbjct: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120

Query: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
           STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD
Sbjct: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180

Query: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
           FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF
Sbjct: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240

Query: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
           LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT
Sbjct: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300

Query: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
           TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP
Sbjct: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360

Query: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGG 420
           VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGG
Sbjct: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGG 420

Query: 421 FTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKL 480
           FTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKL
Sbjct: 421 FTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKL 480

Query: 481 PPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNA 540
           PPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNA
Sbjct: 481 PPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNA 540

Query: 541 ATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFG 600
           ATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFG
Sbjct: 541 ATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFG 600

Query: 601 PVSGAQIQFM 610
           PVSGAQIQFM
Sbjct: 601 PVSGAQIQFM 610


>gi|56788366 phosphatidylinositol-binding clathrin assembly protein
           isoform 1 [Homo sapiens]
          Length = 652

 Score = 1158 bits (2996), Expect = 0.0
 Identities = 602/660 (91%), Positives = 602/660 (91%), Gaps = 58/660 (8%)

Query: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
           MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA
Sbjct: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60

Query: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
           DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM
Sbjct: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120

Query: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
           STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD
Sbjct: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180

Query: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
           FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF
Sbjct: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240

Query: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
           LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT
Sbjct: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300

Query: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
           TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP
Sbjct: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360

Query: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWG- 419
           VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWG 
Sbjct: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGD 420

Query: 420 -------------------------------------------------GFTPSPVAQPH 430
                                                            GFTPSPVAQPH
Sbjct: 421 PFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPH 480

Query: 431 PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL 490
           PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL
Sbjct: 481 PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL 540

Query: 491 DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQ 550
           DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATM       
Sbjct: 541 DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATM------- 593

Query: 551 YAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM 610
            APPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
Sbjct: 594 -APPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM 652


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score =  504 bits (1297), Expect = e-142
 Identities = 268/424 (63%), Positives = 316/424 (74%), Gaps = 49/424 (11%)

Query: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
           MSGQ+LTDRI AAQ+SVTGSAV++ VCKATTHE+MGPKKKHLDYLIQ TNE NVNIPQ+A
Sbjct: 1   MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA 60

Query: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
           D+LFER TNSSWVVVFK+L+TTHHLMV+GNERFIQYLASRNTLFNLSNFLDKSG  GYDM
Sbjct: 61  DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM 120

Query: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
           STFIRRYSRYLNEKA SYRQ+AFDF +VK+GADGVMRTM  EKLLK++PI+Q Q+DALL+
Sbjct: 121 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE 180

Query: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
           F+V+ NELTNGVINAAFMLLFKD I+LFA YN+G+INLLEK+F+MKK QCK+ L+IYK+F
Sbjct: 181 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF 240

Query: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
           LTRMTR+SEFLKVAEQVGID+GDIPDL+QAPSSL++ LEQHL +LEGKK  ++  +   +
Sbjct: 241 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS 300

Query: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
            LS +                                              +  TT  SP
Sbjct: 301 PLSKS----------------------------------------------SPATTVTSP 314

Query: 361 VSTSAGGIMTAPAIDIFSTPSSS--NSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTW 418
            ST A  I T+P +D+F+T S++   STSK  +DLLDL QP F       + A       
Sbjct: 315 NSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDL-QPDFSSGGAAAAAAPAPPPPA 373

Query: 419 GGFT 422
           GG T
Sbjct: 374 GGAT 377



 Score =  149 bits (376), Expect = 7e-36
 Identities = 126/350 (36%), Positives = 175/350 (50%), Gaps = 46/350 (13%)

Query: 293 STAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHT 352
           + AA+  TT S A ++ A   L +      +   +  E  A  K      +   +    +
Sbjct: 540 TAAATTTTTTSAATATTAPPALDIFG----DLFESTPEVAAAPKPDAAPSIDLFSTDAFS 595

Query: 353 SLTTAASPVSTSAGGIMTAP--AIDIFSTPSSSNSTSKLPND---LLDLQQPTFHPSVHP 407
           S    ASPV  S+   +TA   ++D F+ PS + + S    D   ++DL    F  S   
Sbjct: 596 SPPQGASPVPESS---LTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASE 652

Query: 408 MSTASQVAST----------WGGF----TPSPVAQPHPSAGLNVDFESVFG---NKSTNV 450
              ASQ AS+          +GG     +PSPV  P  +  L  +FE+ FG   + S++ 
Sbjct: 653 PQPASQAASSSSASADLLAGFGGSFMAPSPSPVT-PAQNNLLQPNFEAAFGTTPSTSSSS 711

Query: 451 IVDSGGFDELGGLLKPTVASQNQNLPVAKLPPS------KLVSDDLDSSLANLVGNLGIG 504
             D   FD LG LL PT+A   Q  PV+ +PPS      K +  DLDSSLA+LVGNLGI 
Sbjct: 712 SFDPSVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGIS 771

Query: 505 NGTTKN-DVNWSQPGEKKLTGGSNWQPKVAPTTAWNA-----ATMNGMHFP-QYAPPVMA 557
             TTK  D+ W+  GEKKLTGG+NWQPKVAP T W+A     A + G   P    PPV  
Sbjct: 772 GTTTKKGDLQWNA-GEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTSSVPPVAG 829

Query: 558 YPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQI 607
            P+    G  G+G+PP    +P+M Q  ++++QP+MRPP     V G Q+
Sbjct: 830 APSVGQPG-AGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQL 878


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 37.7 bits (86), Expect = 0.031
 Identities = 74/329 (22%), Positives = 119/329 (36%), Gaps = 43/329 (13%)

Query: 286  EGKKIKDSTAASRATTLSN-------AVSSLASTGLSLTKVDEREKQAALEEEQ-----A 333
            EG  I  S  +   T L++        VSS A+T LS T VD + + A   E       A
Sbjct: 1146 EGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANT-LSTTPVDSKTQVATSTEASSPPPTA 1204

Query: 334  RLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDL 393
             + ++      E +  P TS+    +PV++S    ++   +D  +  ++S  TS  P   
Sbjct: 1205 EVTSMPTSTPGERST-PLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTA 1263

Query: 394  LDLQQPTFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVD 453
                 PT   S       S   ST      + V  P  S  L    ++     ++N +  
Sbjct: 1264 EGTSLPTSTTSEGSTLLTSIPVST------TLVTSPEASTLLTTPVDTKGPVVTSNEVSS 1317

Query: 454  SGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGT--TKND 511
            S    E  G   PT        P+  +P +  +   + SS  +++    + N T  T + 
Sbjct: 1318 SPTPAE--GTSMPTSTYSEGRTPLTSIPVNTTL---VASSAISILSTTPVDNSTPVTTST 1372

Query: 512  VNWSQPGEKKLTGGSNWQP------------KVAPTTAWNAATMNGMHFPQYAPPVMAYP 559
               S P   + T   N  P               P  +  A+T++        P   +  
Sbjct: 1373 EACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAE 1432

Query: 560  AT-TPTGMIGYGIP---PQMGSVPVMTQP 584
            AT +PT   G  IP   P  G  P+ + P
Sbjct: 1433 ATSSPTTAEGISIPTSTPSEGKTPLKSIP 1461



 Score = 37.0 bits (84), Expect = 0.053
 Identities = 68/310 (21%), Positives = 114/310 (36%), Gaps = 32/310 (10%)

Query: 286  EGKKIKDSTAASRATTLSNAV-------SSLASTGLSLTKVDEREKQAALEEEQARLKAL 338
            EG  +  ST   R+T L+N +       +S AST LS T VD         E  +     
Sbjct: 2678 EGSSMPTSTPGERSTPLTNILVSTTLLANSEAST-LSTTPVDTSTPVTTSAEASSSPTTA 2736

Query: 339  KEQRLK----ELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLL 394
            +   ++         P TS+  +  PV++S    ++  A+D     ++S   S  P    
Sbjct: 2737 EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAE 2796

Query: 395  DLQQPTFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDS 454
                PT  PS     T++ + S     TP   ++    +   VD  +     +T+    S
Sbjct: 2797 VTSMPTSTPS----ETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPV---TTSTKASS 2849

Query: 455  GGFDELGGLLKPTVASQNQNL---------PVAKLPPSKLVSDDLDSSLANLVGNLGIGN 505
                  G ++  + AS+   L         PVA    S L +  +D+S+       G  +
Sbjct: 2850 SPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSS 2909

Query: 506  GTTKNDVNW--SQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAP-PVMAYPATT 562
             TT    +   S P E   T  ++      P     A+T++        P    A  +++
Sbjct: 2910 PTTAEGTSMPISTPSEVS-TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSS 2968

Query: 563  PTGMIGYGIP 572
            PT   G  +P
Sbjct: 2969 PTTAEGTSMP 2978



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 77/349 (22%), Positives = 122/349 (34%), Gaps = 42/349 (12%)

Query: 268  SQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNA-------VSSLASTGLSLTKVD 320
            S +P      +     S EG  +  ST +  +T L +         SS AST LS T VD
Sbjct: 2542 SNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST-LSTTPVD 2600

Query: 321  EREKQAALEEEQARLKALKEQRLK-ELAKKPHTSLTT---AASPVSTSAGGIMTAPAIDI 376
                     E  +     K+  +      +  TSLT+   +  PV++S    ++   +D 
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDT 2660

Query: 377  FSTPSSSNSTSKLPNDLLDLQQPTFHPS----------VHPMSTASQVASTWGGFTPSPV 426
             +  ++S  TS  P        PT  P           V     A+  AST    TP   
Sbjct: 2661 RTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTL-STTPVDT 2719

Query: 427  AQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLV 486
            + P  ++       +     S  +   S G   L  +L  T       LPVA    S + 
Sbjct: 2720 STPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVST-------LPVASSEASTVS 2772

Query: 487  SDDLDSSLANLVGNLGIGNGTTK--NDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMN 544
            +  +D+S+          + TT     +  S P E   T  ++      P  +  A T++
Sbjct: 2773 TTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETS-TPLTSMPVNHTPVASSEAGTLS 2831

Query: 545  GMHFPQYAPPVMAYPA-TTPTGMIGYGIP--------PQMGSVPVMTQP 584
                    P   +  A ++PT   G  +P          + S+PV T P
Sbjct: 2832 TTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP 2880



 Score = 33.5 bits (75), Expect = 0.59
 Identities = 70/319 (21%), Positives = 114/319 (35%), Gaps = 57/319 (17%)

Query: 286  EGKKIKDSTAASRATTL-----------SNAVSSLASTGLSLTKVDEREKQAALEEEQAR 334
            EG  ++ ST + R T L           S+A+S+L++T +  +       +A      + 
Sbjct: 2147 EGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 2206

Query: 335  LKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIF----------STPSSSN 384
              ++      E    P TS+  +  PV TS    ++A  +D            S+P+++ 
Sbjct: 2207 GTSMPTSTPSE-GSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAE 2265

Query: 385  STSKLPNDLLDLQQP-TFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVF 443
             TS   + L +   P T  P  H +   S+V++     TP             VD  + F
Sbjct: 2266 GTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL--STTP-------------VDSNTPF 2310

Query: 444  GNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGI 503
                T     S       G   PT  S   N P+ ++P S  +    ++S  +       
Sbjct: 2311 ----TTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS------- 2359

Query: 504  GNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTP 563
               TT  D   S P       GS+  P  A  T+   +T +    P  + PV   P  + 
Sbjct: 2360 ---TTPADT--STPVTTYSQAGSS--PTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS 2412

Query: 564  TGMIGYGIPPQMGSVPVMT 582
                 +   P   S PV T
Sbjct: 2413 EAST-HSTTPVDTSTPVTT 2430



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 72/339 (21%), Positives = 127/339 (37%), Gaps = 35/339 (10%)

Query: 268 SQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREK--- 324
           S+A SS   A +  +A+      + ST  +     +  V+S  ++ LS T VD + +   
Sbjct: 428 SEASSSPTTAEDTSIAT--STPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT 485

Query: 325 --QAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSS 382
             +A+     A + ++      E    P TS++ +  PV++S    ++   +D  +  ++
Sbjct: 486 STEASSSPPTAEVNSMPTSTPSE-GSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTT 544

Query: 383 SNSTSKLPNDLLDLQQPTFHPSV-------HPMSTASQVASTWGGFTPSPVAQPHPSAGL 435
           S+  S           PT  PS         P+ST   V+S     + +P       +  
Sbjct: 545 SSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA-----DSNT 599

Query: 436 NVDFESVFGNKST---NVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDS 492
            V   S   + ST      + +  + E G  +  T  S +  L VA    S L +  +DS
Sbjct: 600 FVTTSSEASSSSTTAEGTSMPTSTYSERGTTI--TSMSVSTTL-VASSEASTLSTTPVDS 656

Query: 493 SLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTT---AWNAATMNGMHFP 549
           +           + TT      S P      G +        TT   +  A+T++     
Sbjct: 657 NTPVTTSTEATSSSTTAEGT--SMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD 714

Query: 550 QYAPPVMAYPA-TTPTGMIGYGIP---PQMGSVPVMTQP 584
              P   +  A ++PT   G  +P   P  GS P+ + P
Sbjct: 715 TSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP 753



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 67/330 (20%), Positives = 111/330 (33%), Gaps = 40/330 (12%)

Query: 286  EGKKIKDSTAASRATTLSNA------VSSLASTGLSLTKVD---------EREKQAALEE 330
            EG  I  ST +   T L++       V+S  ++ LS T VD         E        E
Sbjct: 3208 EGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAE 3267

Query: 331  EQARLKALKEQRLKELAKKPHTSLTTAAS--------------PVSTSAGGIMTAPAIDI 376
              +   +   +    L   P ++ T A+S              PV+T +    + P  D 
Sbjct: 3268 GTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADG 3327

Query: 377  FSTPSSSNSTSKLP-NDLLDLQQPTFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGL 435
             S P+S+ S    P  ++     P        +ST     ST    T S  A   P+   
Sbjct: 3328 TSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTST--PVTTSTEASLSPTTAE 3385

Query: 436  NVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLD-SSL 494
                 +   ++ T  +        +     P V+S+   L    +  + LV+   + SS 
Sbjct: 3386 GTSIPTSSPSEGTTPLA------SMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSS 3439

Query: 495  ANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPP 554
              +     +   TT              T  ++ +     TT  + +T      P  + P
Sbjct: 3440 PTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSP 3499

Query: 555  VMAYPATTPTGMIGYGIPPQMGSVPVMTQP 584
              A   + PT   G G  P + ++PV T P
Sbjct: 3500 TTAEVTSMPTSTAGEGSTP-LTNMPVSTTP 3528



 Score = 30.0 bits (66), Expect = 6.5
 Identities = 63/318 (19%), Positives = 116/318 (36%), Gaps = 31/318 (9%)

Query: 286  EGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKE 345
            EG  +  S   S     S   S+L++T +          + +     A   ++      E
Sbjct: 1628 EGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTE 1687

Query: 346  LAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSV 405
              + P TS+T   +PV++SA   ++   +D  +  ++S      P        P   PS 
Sbjct: 1688 -GRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSE 1746

Query: 406  H-------PMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFD 458
                    P+ST   ++S     + +P+    P         S    + T++   +    
Sbjct: 1747 GTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTST---- 1802

Query: 459  ELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTK---NDVNWS 515
             L   + P  ++   +  VA    S L +  +DS+ + +V +  + +  T      +  S
Sbjct: 1803 -LSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSN-SPVVTSTAVSSSPTPAEGTSIATS 1860

Query: 516  QPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQY-APPVMAYP--ATTPTGMIGYGIP 572
             P E      S     V+ TT  ++ T      P   + PV  Y   +++PT   G  +P
Sbjct: 1861 TPSEGSTALTS---IPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMP 1917

Query: 573  --------PQMGSVPVMT 582
                    P + S+PV T
Sbjct: 1918 TSTPREGRPPLTSIPVST 1935


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 59/239 (24%), Positives = 86/239 (35%), Gaps = 41/239 (17%)

Query: 350  PHTSLTTAASPVS---TSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVH 406
            PH S  T  SP S   T+ G           +TPS + +++ LP+       PT  P   
Sbjct: 4542 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSS------PTSAPITT 4595

Query: 407  PMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKP 466
             ++T  +    W  +       P PS G   DF++      +N+    G   E    L+ 
Sbjct: 4596 VVTTGCEPQCAWSEWLDYSYPMPGPSGG---DFDTY-----SNIRAAGGAVCEQPLGLEC 4647

Query: 467  TVASQNQNLPVAKLPPSKLVSDDLDSSLA----NLVGNLGI-----------GNGTTKND 511
               +Q   +P+ +L   ++V   LD  L       VG   +             G   + 
Sbjct: 4648 RAQAQ-PGVPLGEL--GQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPST 4704

Query: 512  VNWSQPGEKKLTGGSNW----QPKVAPTTAWNAATMNGMHFPQYAPP--VMAYPATTPT 564
               S       T G+ W        A TTA   +T      P  APP  V+  PATTPT
Sbjct: 4705 PATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPT 4763



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 35/162 (21%), Positives = 59/162 (36%), Gaps = 19/162 (11%)

Query: 283  ASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQR 342
            A+  G+ +  S+  +  T  ++A S +  T    T + E    + +            Q 
Sbjct: 3980 ATTHGRSLPPSSPHTVRTAWTSATSGILGT----THITE---PSTVTSHTPAATTSTTQH 4032

Query: 343  LKELAKKPHTSLTTAASPVS---TSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQP 399
                   PH S  T  SP S   T+ G           +TPS + +++ LP+       P
Sbjct: 4033 STPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSS------P 4086

Query: 400  TFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFES 441
            T  P    ++T  +    W  +       P PS G   DF++
Sbjct: 4087 TSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGG---DFDT 4125


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 44/157 (28%), Positives = 60/157 (38%), Gaps = 30/157 (19%)

Query: 469 ASQNQNLPVAKLPPSKLVS----DDLDSSLANLVG---NLGIGNGTTKNDVNWSQPGEKK 521
           +S++Q +P   +  S   S     +L+  L N  G   NLG+ N T  N      P    
Sbjct: 293 SSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVG 352

Query: 522 LTGGSNW----QPKVAPTTAWNAATMNGMHFPQ----YAPP-------VMAYPATTPTGM 566
               S      Q  + P+ + N      MH  Q    YA P        M+ PA TP   
Sbjct: 353 FPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQ 412

Query: 567 I---GYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFG 600
           +     GIP ++GS P M  P     QP  +PP   G
Sbjct: 413 VRPGSAGIPMEVGSYPNMPHP-----QPSHQPPGAMG 444


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 59/239 (24%), Positives = 86/239 (35%), Gaps = 41/239 (17%)

Query: 350  PHTSLTTAASPVS---TSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVH 406
            PH S  T  SP S   T+ G           +TPS + +++ LP+       PT  P   
Sbjct: 4072 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSS------PTSAPITT 4125

Query: 407  PMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKP 466
             ++T  +    W  +       P PS G   DF++      +N+    G   E    L+ 
Sbjct: 4126 VVTTGCEPQCAWSEWLDYSYPMPGPSGG---DFDTY-----SNIRAAGGAVCEQPLGLEC 4177

Query: 467  TVASQNQNLPVAKLPPSKLVSDDLDSSLA----NLVGNLGI-----------GNGTTKND 511
               +Q   +P+ +L   ++V   LD  L       VG   +             G   + 
Sbjct: 4178 RAQAQ-PGVPLGEL--GQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPST 4234

Query: 512  VNWSQPGEKKLTGGSNW----QPKVAPTTAWNAATMNGMHFPQYAPP--VMAYPATTPT 564
               S       T G+ W        A TTA   +T      P  APP  V+  PATTPT
Sbjct: 4235 PATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPT 4293



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 35/162 (21%), Positives = 59/162 (36%), Gaps = 19/162 (11%)

Query: 283  ASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQR 342
            A+  G+ +  S+  +  T  ++A S +  T    T + E    + +            Q 
Sbjct: 3455 ATTHGRSLPPSSPHTVRTAWTSATSGILGT----THITE---PSTVTSHTPAATTSTTQH 3507

Query: 343  LKELAKKPHTSLTTAASPVS---TSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQP 399
                   PH S  T  SP S   T+ G           +TPS + +++ LP+       P
Sbjct: 3508 STPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSS------P 3561

Query: 400  TFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFES 441
            T  P    ++T  +    W  +       P PS G   DF++
Sbjct: 3562 TSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGG---DFDT 3600


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 37.0 bits (84), Expect = 0.053
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 19/140 (13%)

Query: 210 AYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ 269
           A  E  I  L++  D  + + +E +D YKK L  +          E+V + +GD   LS+
Sbjct: 623 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK---------EKVSLLQGD---LSE 670

Query: 270 APSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALE 329
             +SLLD L++H +SL    +K     SR  TL  A+       L +    ++  +AALE
Sbjct: 671 KEASLLD-LKEHASSLASSGLKKD---SRLKTLEIALEQKKEECLKMESQLKKAHEAALE 726

Query: 330 EEQARLKALKEQRLKELAKK 349
              AR       R++ L ++
Sbjct: 727 ---ARASPEMSDRIQHLERE 743



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 70/327 (21%), Positives = 126/327 (38%), Gaps = 37/327 (11%)

Query: 41  HLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERF------- 93
           HL+ L++   + N  + +     FE   +S+     +++I      +   ER        
Sbjct: 345 HLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404

Query: 94  IQYLASRNTLFNLSNFLDKSGLQGY-DMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGA 152
           IQ L S   L       +   ++ Y   S F++     L E+  S      +  K   G 
Sbjct: 405 IQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGL 464

Query: 153 DGVMRTMNTEKLLKTVPII--QNQMDALLD--------FNVNSNELTNGVINAAFMLLFK 202
              +  +  E   K   ++  Q +++ L +          V    LT     AA +    
Sbjct: 465 QAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEV 524

Query: 203 DAIRLFAAYNEGIINLLEKYF-DMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQ-VGID 260
           DA+RL     E ++N   K   DM + +  +  +I+         + + L V E+ V + 
Sbjct: 525 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD--------LKDMLDVKERKVNVL 576

Query: 261 RGDIPDLSQA---PSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLT 317
           +  I +L +        + +L++ + SL+       TA    TTL  A++    T   L 
Sbjct: 577 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTAL---TTLEEALAEKERTIERLK 633

Query: 318 KV---DEREKQAALEEEQARLKALKEQ 341
           +    DEREKQ  ++  +  LK LKE+
Sbjct: 634 EQRDRDEREKQEEIDNYKKDLKDLKEK 660


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 37.0 bits (84), Expect = 0.053
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 19/140 (13%)

Query: 210 AYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ 269
           A  E  I  L++  D  + + +E +D YKK L  +          E+V + +GD   LS+
Sbjct: 595 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK---------EKVSLLQGD---LSE 642

Query: 270 APSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALE 329
             +SLLD L++H +SL    +K     SR  TL  A+       L +    ++  +AALE
Sbjct: 643 KEASLLD-LKEHASSLASSGLKKD---SRLKTLEIALEQKKEECLKMESQLKKAHEAALE 698

Query: 330 EEQARLKALKEQRLKELAKK 349
              AR       R++ L ++
Sbjct: 699 ---ARASPEMSDRIQHLERE 715



 Score = 32.7 bits (73), Expect = 1.00
 Identities = 67/313 (21%), Positives = 125/313 (39%), Gaps = 37/313 (11%)

Query: 41  HLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASR 100
           HL+ L++   + N  + +     FE   +S+     +++I      +   ER ++ L   
Sbjct: 345 HLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404

Query: 101 NTLFNLSNFLD-KSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTM 159
             +   +  L  +   +        R +S+++  K    +Q               +   
Sbjct: 405 IQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQE--------------LSRK 450

Query: 160 NTEKL-LKT-VPIIQNQM-DALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGII 216
           +TE L L+T +  + NQ  D+     V    LT     AA +    DA+RL     E ++
Sbjct: 451 DTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETML 510

Query: 217 NLLEKYF-DMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQ-VGIDRGDIPDLSQA---P 271
           N   K   DM + +  +  +I+         + + L V E+ V + +  I +L +     
Sbjct: 511 NKKTKQIQDMAEEKGTQAGEIHD--------LKDMLDVKERKVNVLQKKIENLQEQLRDK 562

Query: 272 SSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKV---DEREKQAAL 328
              + +L++ + SL+       TA    TTL  A++    T   L +    DEREKQ  +
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTAL---TTLEEALAEKERTIERLKEQRDRDEREKQEEI 619

Query: 329 EEEQARLKALKEQ 341
           +  +  LK LKE+
Sbjct: 620 DNYKKDLKDLKEK 632


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 37.0 bits (84), Expect = 0.053
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 8/82 (9%)

Query: 351  HTS--LTTAASPVSTSAGGIMTAPAIDIFSTPSS---SNSTSKLPNDLLDLQQPTFHPSV 405
            HT+  +T   S  S +     TA A   F + SS    NS+S+ P+  +  Q P    + 
Sbjct: 2059 HTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSAT 2118

Query: 406  HPMSTASQVASTWGGFTPSPVA 427
             P+ST +Q++S+   F+PSP A
Sbjct: 2119 TPVSTTNQLSSS---FSPSPSA 2137



 Score = 33.9 bits (76), Expect = 0.45
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 351  HTSLTTAASPVST--SAGGIMTAPAIDIFSTPSS----SNSTSKLPNDLLDLQQPTFHPS 404
            H++ T    P +T  + G   TAP I   ++ +S    S ST+K P  L      T HP 
Sbjct: 1477 HSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPE 1536

Query: 405  VHPMSTASQVASTWGGFTPSPVA 427
            V P ST +   +     T +PVA
Sbjct: 1537 VTPTSTTTITPNPTSTRTRTPVA 1559



 Score = 33.1 bits (74), Expect = 0.77
 Identities = 71/319 (22%), Positives = 103/319 (32%), Gaps = 28/319 (8%)

Query: 300  TTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAAS 359
            TTL    S+  +  ++LT     +  ++L   +              A+   TS TT  +
Sbjct: 1657 TTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTS-TTNIT 1715

Query: 360  PVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWG 419
            P  TS G           S   SS ST+K    L      T HP V   ST S   +   
Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775

Query: 420  GFTPSPVAQ--PHPSAGLNVDFESVFGNKSTNVIVDSGGFDELG---GLLKPTVASQNQN 474
              T +PVA      S+ L   F +      T  I  +G             PT +  +  
Sbjct: 1776 TGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTT 1835

Query: 475  LPV--------AKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGS 526
            LP            P +  V     + +A       +  GT         P   K TG +
Sbjct: 1836 LPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI------PPPTTIKATGST 1889

Query: 527  NWQPKVAPTTAWNAATMNGMHFPQ------YAPPVMAYPATTPTGMIGYGIPPQMGSVPV 580
            +  P + PTT+  + + +     +      Y      +P  TPT      I P+  S   
Sbjct: 1890 HTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTT--NITPKHTSTGT 1947

Query: 581  MTQPTLIYSQPVMRPPNPF 599
             T      S    R P PF
Sbjct: 1948 RTPVAHTTSASSSRLPTPF 1966


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 36.6 bits (83), Expect = 0.069
 Identities = 65/257 (25%), Positives = 102/257 (39%), Gaps = 46/257 (17%)

Query: 346  LAKKPHTSLTTAASPV-STSAGGIMTAPAI--DIFSTP-SSSNSTSKLPNDLLDLQQPTF 401
            L   P T+ +++AS V  TS  G  ++P++   +F T   +SN+T+              
Sbjct: 1965 LTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAP 2024

Query: 402  HPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELG 461
              + +PM TA +        +PSP AQP    G++ +     G+ S N +  S    E G
Sbjct: 2025 TNATYPMPTAKEHYPVSSPSSPSPPAQP---GGVSRNSPLDCGSASPNKVASSSE-QEAG 2080

Query: 462  GLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQ--PGE 519
                P V + N        PP+   S    S+ +N     G  +   +  +  SQ  P E
Sbjct: 2081 S--PPVVETTNTR------PPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPE 2132

Query: 520  KKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVP 579
             ++T      P +A ++A                PV A P+T P   + Y +P      P
Sbjct: 2133 VRMT-----VPPLATSSA----------------PV-AVPSTAP---VTYPMPQTPMGCP 2167

Query: 580  VMTQPTLIYSQPVMRPP 596
               QPT     P +RPP
Sbjct: 2168 ---QPTPKMETPAIRPP 2181


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 36.6 bits (83), Expect = 0.069
 Identities = 65/257 (25%), Positives = 102/257 (39%), Gaps = 46/257 (17%)

Query: 346  LAKKPHTSLTTAASPV-STSAGGIMTAPAI--DIFSTP-SSSNSTSKLPNDLLDLQQPTF 401
            L   P T+ +++AS V  TS  G  ++P++   +F T   +SN+T+              
Sbjct: 1714 LTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAP 1773

Query: 402  HPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELG 461
              + +PM TA +        +PSP AQP    G++ +     G+ S N +  S    E G
Sbjct: 1774 TNATYPMPTAKEHYPVSSPSSPSPPAQP---GGVSRNSPLDCGSASPNKVASSSE-QEAG 1829

Query: 462  GLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQ--PGE 519
                P V + N        PP+   S    S+ +N     G  +   +  +  SQ  P E
Sbjct: 1830 S--PPVVETTNTR------PPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPE 1881

Query: 520  KKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVP 579
             ++T      P +A ++A                PV A P+T P   + Y +P      P
Sbjct: 1882 VRMT-----VPPLATSSA----------------PV-AVPSTAP---VTYPMPQTPMGCP 1916

Query: 580  VMTQPTLIYSQPVMRPP 596
               QPT     P +RPP
Sbjct: 1917 ---QPTPKMETPAIRPP 1930


>gi|13489073 egl nine homolog 1 [Homo sapiens]
          Length = 426

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 42/170 (24%), Positives = 66/170 (38%), Gaps = 15/170 (8%)

Query: 324 KQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSS 383
           ++AA   + A   A K +    +  KP      AASP   +AGG  +A A +        
Sbjct: 94  RKAAARRDNASGDAAKGK----VKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEP 149

Query: 384 NSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVF 443
            + S L  +  +L  P+        +T     S  GG  P+   +P P+  L +++    
Sbjct: 150 PARSSLFQEKANLYPPS--------NTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPC 201

Query: 444 GNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSS 493
            NK    +VD     E G  +   V + +      K    +LVS   DSS
Sbjct: 202 MNKHGICVVDDFLGKETGQQIGDEVRALHD---TGKFTDGQLVSQKSDSS 248


>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo
           sapiens]
          Length = 559

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 68/279 (24%), Positives = 105/279 (37%), Gaps = 43/279 (15%)

Query: 321 EREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGG-IMTAPAIDIFST 379
           E+EK+A  +++ A L    E+        P +  +     V  +AGG    AP++   + 
Sbjct: 109 EQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAK 168

Query: 380 PSSSNST-SKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGGFTPSPVAQPHPSAGLNVD 438
              SNST SK+P     LQ  T  P     S+A    +    F+ S + QP  +   +  
Sbjct: 169 DKVSNSTLSKIP----ALQGSTKSPR---YSSACPSTTKRATFSDSLLIQPTSAGSTDRL 221

Query: 439 FESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLV 498
             S  GNK               G+ K      +   P + LPP + VS D D +  +L 
Sbjct: 222 PYSKSGNKD--------------GVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLN 267

Query: 499 GNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYA------ 552
            ++      T      S+P  +    G++      PTT  + A   G   P Y+      
Sbjct: 268 SSISSSARRTTR----SEPIRRAGKSGTS-----TPTTPGSTAITPGTP-PSYSSRTPGT 317

Query: 553 PPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQP 591
           P   +YP T  T     G P     VP   +  +I + P
Sbjct: 318 PGTPSYPRTPHTP----GTPKSAILVPSEKKVAIIRTPP 352


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 3/82 (3%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P T+ TT   P +T +  I T       +TPS   ST+  P        PT  PS  P +
Sbjct: 1424 PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPS-PPTT 1482

Query: 410  TASQVASTWGGFTPSPVAQPHP 431
            T S   +T    TP P   P P
Sbjct: 1483 TPSPPTTT--TTTPPPTTTPSP 1502



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 4/83 (4%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P T  TT   P +T +    T       +TPS   +T   P        PT  PS  P +
Sbjct: 1588 PPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1647

Query: 410  TASQVASTWGGFTPSPVAQPHPS 432
            T +   +T    TPSP     PS
Sbjct: 1648 TTTPPPTT----TPSPPTTTTPS 1666



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 4/83 (4%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P T+  T  SP +T +  I T       +TPS   +T   P+       PT   +  P +
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPT 1750

Query: 410  TASQVASTWGGFTPSPVAQPHPS 432
            T S   +T    TP P +   P+
Sbjct: 1751 TTSSPLTT----TPLPPSITPPT 1769



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 7/82 (8%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P   +TT  +P  T      T P+  I +TPS   +T   P+       P    +  P S
Sbjct: 1665 PSPPITTTTTPPPT------TTPSSPITTTPSPPTTTMTTPSPTTTPSSP-ITTTTTPSS 1717

Query: 410  TASQVASTWGGFTPSPVAQPHP 431
            T +         TPSP   P P
Sbjct: 1718 TTTPSPPPTTMTTPSPTTTPSP 1739



 Score = 29.6 bits (65), Expect = 8.5
 Identities = 23/78 (29%), Positives = 30/78 (38%), Gaps = 4/78 (5%)

Query: 355  TTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQV 414
            TT   P +T +    T       +TPS   +T   P        PT  PS  P +T +  
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573

Query: 415  ASTWGGFTPSPVAQPHPS 432
             +T    TPSP     PS
Sbjct: 1574 PTT----TPSPPTTTTPS 1587


>gi|117190342 PHD finger protein 2 [Homo sapiens]
          Length = 1096

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 324  KQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSS 383
            K +  EE++++ K   +++L      P TS + +A   STS     T PA    +TP+S+
Sbjct: 940  KLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTSISAGTTSTSTTPASTTPA---STTPAST 996

Query: 384  NSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGGFT 422
            ++ S   +   +   P   P  H  S A    +  G FT
Sbjct: 997  STASSQASQ--EGSSPEPPPESHSSSLADHEYTAAGTFT 1033


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 21/122 (17%)

Query: 261 RGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVD 320
           +  I +LSQA   L  A + H A L  +    ++  S  TTL NA        L+  K  
Sbjct: 472 QSSISNLSQAKEELEQASQAHGARLTAQV---ASLTSELTTL-NATIQQQDQELAGLKQQ 527

Query: 321 EREKQAAL-----EEEQA------RLKAL------KEQRLKELAKKPHTSLTTAASPVST 363
            +EKQA L     ++EQA      +++ L      KEQ+LKE+A+K   +    A  ++T
Sbjct: 528 AKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLAT 587

Query: 364 SA 365
           +A
Sbjct: 588 AA 589


>gi|236459851 ubinuclein 2 [Homo sapiens]
          Length = 1347

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 64/260 (24%), Positives = 99/260 (38%), Gaps = 30/260 (11%)

Query: 336  KALKEQRLKELAKKPHTSLTT---AASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPND 392
            KA+  Q   +  K P +   +   AASP   ++   + +P       PS S   S +   
Sbjct: 1016 KAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLPSPKPSASPKPSLSAKPS-VSTK 1074

Query: 393  LLDLQQPTFHPSVHPMSTASQVASTWGGF--TPSPV-AQPHPSAGLNVDFESVFGNKSTN 449
            L+    PT  P+V P S++       G    T SPV  QP   +G+N+  +S     + N
Sbjct: 1075 LISKSNPTPKPTVSPSSSSPNALVAQGSHSSTNSPVHKQP---SGMNISRQS----PTLN 1127

Query: 450  VIVDS--GGFDELGGLLKP----------TVASQNQNLPVAKLPPSKLVSDDLDSSLANL 497
            ++  S   G      L  P          TV   + +     +P S+    +L+SS AN 
Sbjct: 1128 LLPSSRTSGLPPTKNLQAPSKLTNSSSTGTVGKNSLSGIAMNVPASR--GSNLNSSGANR 1185

Query: 498  VG-NLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPV- 555
               + G G+GT       S P       GS+       +TA  +   N         P+ 
Sbjct: 1186 TSLSGGTGSGTQGATKPLSTPHRPSTASGSSVVTASVQSTAGASLLANASPLTLMTSPLS 1245

Query: 556  MAYPATTPTGMIGYGIPPQM 575
            +     TP GM+G  +P  M
Sbjct: 1246 VTNQNVTPFGMLGGLVPVTM 1265


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 19/116 (16%)

Query: 288 KKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELA 347
           KK K +T     T      ++   T  + TK  E+EK+   E+E+ + K  ++++ K+  
Sbjct: 44  KKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKK 103

Query: 348 KKPH------------------TSLTTAASPVSTSAGGIMTAPAIDIF-STPSSSN 384
           KK                    + +TTAA+      G ++ A  + I  S+PS S+
Sbjct: 104 KKKKKKKKKLNAKVCGLEIASWSEMTTAAAGEGEEQGSMVQAAGVSISNSSPSRSD 159


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 29/130 (22%), Positives = 63/130 (48%), Gaps = 15/130 (11%)

Query: 226  KKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASL 285
            K+++ ++ L   + F   +  + E+L  AEQ    RG +PD ++A  SL+D  ++ +  +
Sbjct: 5304 KQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKV 5363

Query: 286  EGKKIKDSTAASRA------------TTLSNAVSSLAS---TGLSLTKVDEREKQAALEE 330
            E K++  ++A +              TT+ + ++ + +     L+  K  ++  + AL E
Sbjct: 5364 EEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSE 5423

Query: 331  EQARLKALKE 340
              A  + L+E
Sbjct: 5424 LVANAELLEE 5433


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 29/130 (22%), Positives = 63/130 (48%), Gaps = 15/130 (11%)

Query: 226  KKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASL 285
            K+++ ++ L   + F   +  + E+L  AEQ    RG +PD ++A  SL+D  ++ +  +
Sbjct: 4802 KQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKV 4861

Query: 286  EGKKIKDSTAASRA------------TTLSNAVSSLAS---TGLSLTKVDEREKQAALEE 330
            E K++  ++A +              TT+ + ++ + +     L+  K  ++  + AL E
Sbjct: 4862 EEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSE 4921

Query: 331  EQARLKALKE 340
              A  + L+E
Sbjct: 4922 LVANAELLEE 4931


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 35/148 (23%), Positives = 67/148 (45%), Gaps = 14/148 (9%)

Query: 231  KEGLDIYKKFLTRMTRISEFLKVAEQVG---IDRGDIPDLSQAP--------SSLLDALE 279
            K  L IYKKFL +   ++  LK  +  G   ++    P  S+ P         SLL  L+
Sbjct: 2179 KAQLKIYKKFLKKAQDLTSLLKELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQ 2238

Query: 280  QHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALK 339
              + +L+G   +  +     T L+  + + +   +S +  D+   Q A+EE+  +L+ L+
Sbjct: 2239 DSVQNLDGHVREHDSYQVCVTDLNTTLDNFSKEFVSFS--DKPVDQIAVEEKLQKLQELE 2296

Query: 340  EQ-RLKELAKKPHTSLTTAASPVSTSAG 366
             +  L++   K   +L  +    ++S G
Sbjct: 2297 NRLSLQDGTLKKILALAKSVKQNTSSVG 2324


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 34.3 bits (77), Expect = 0.34
 Identities = 35/148 (23%), Positives = 67/148 (45%), Gaps = 14/148 (9%)

Query: 231  KEGLDIYKKFLTRMTRISEFLKVAEQVG---IDRGDIPDLSQAP--------SSLLDALE 279
            K  L IYKKFL +   ++  LK  +  G   ++    P  S+ P         SLL  L+
Sbjct: 2179 KAQLKIYKKFLKKAQDLTSLLKELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQ 2238

Query: 280  QHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALK 339
              + +L+G   +  +     T L+  + + +   +S +  D+   Q A+EE+  +L+ L+
Sbjct: 2239 DSVQNLDGHVREHDSYQVCVTDLNTTLDNFSKEFVSFS--DKPVDQIAVEEKLQKLQELE 2296

Query: 340  EQ-RLKELAKKPHTSLTTAASPVSTSAG 366
             +  L++   K   +L  +    ++S G
Sbjct: 2297 NRLSLQDGTLKKILALAKSVKQNTSSVG 2324


>gi|7661968 epsin 4 [Homo sapiens]
          Length = 625

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 14/142 (9%)

Query: 20  SAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERT---TNSSWVVVF 76
           S +   V +AT  +  GP  + +  + + T  M    P+L + L+ R       +W  V+
Sbjct: 22  SEIESKVREATNDDPWGPSGQLMGEIAKATF-MYEQFPELMNMLWSRMLKDNKKNWRRVY 80

Query: 77  KSLITTHHLMVYGNERFIQYLASRNTLFNLS-----NFLDKSGLQGYDMSTFIRRYSRYL 131
           KSL+   +L+  G+ER +   ++R  +++L      +F+D+    G D    IR+  + L
Sbjct: 81  KSLLLLAYLIRNGSERVV--TSAREHIYDLRSLENYHFVDE---HGKDQGINIRQKVKEL 135

Query: 132 NEKAVSYRQVAFDFTKVKRGAD 153
            E A    ++  +  K K+  D
Sbjct: 136 VEFAQDDDRLREERKKAKKNKD 157


>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
           [Homo sapiens]
          Length = 1634

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 43/180 (23%), Positives = 66/180 (36%), Gaps = 20/180 (11%)

Query: 308 SLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGG 367
           SL S G+S  ++   E   AL+ E   L  L+  + +  AK+        A P   S   
Sbjct: 13  SLESVGISRKELAMAE---ALQMEYDALSRLRHDKEENRAKQN-------ADPSLIS--- 59

Query: 368 IMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGGFTPSPVA 427
               P +D +S P+   +  KL   L        + S+ P       +++ G   P P +
Sbjct: 60  -WDEPGVDFYSKPAGRRTDLKLLRGLSGSDPTLNYNSLSPQEGPPNHSTSQG---PQPGS 115

Query: 428 QPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLK---PTVASQNQNLPVAKLPPSK 484
            P P   L+ D+  +F      V    G  D  G   K   P +  +        LPP K
Sbjct: 116 DPWPKGSLSGDYLYIFDGSDGGVSSSPGPGDIEGSCKKLSPPPLPPRASIWDTPPLPPRK 175


>gi|188497758 ubiquitin associated protein 2-like isoform a [Homo
           sapiens]
          Length = 1087

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 49/182 (26%), Positives = 74/182 (40%), Gaps = 46/182 (25%)

Query: 264 IPDLSQAPS--SLLDALEQHLASLEG----KKIKDSTAASRATTLS---NAVSSLASTGL 314
           IP L++  S  SLL    QH +SL G    ++I ++T    ++TLS   N +SS  S+G 
Sbjct: 653 IPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGR 712

Query: 315 SLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAI 374
           + T                         L   + +   +L +++S  ST++  +   P  
Sbjct: 713 TSTST-----------------------LLHTSVESEANLHSSSSTFSTTSSTVSAPP-- 747

Query: 375 DIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGGFTPS-----PVAQP 429
            + S  SS NS S L   L      T        ST S VA+T G   P+     P   P
Sbjct: 748 PVVSVSSSLNSGSSLGLSLGSNSTVT-------ASTRSSVATTSGKAPPNLPPGVPPLLP 800

Query: 430 HP 431
           +P
Sbjct: 801 NP 802


>gi|188497756 ubiquitin associated protein 2-like isoform b [Homo
           sapiens]
          Length = 983

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 49/182 (26%), Positives = 74/182 (40%), Gaps = 46/182 (25%)

Query: 264 IPDLSQAPS--SLLDALEQHLASLEG----KKIKDSTAASRATTLS---NAVSSLASTGL 314
           IP L++  S  SLL    QH +SL G    ++I ++T    ++TLS   N +SS  S+G 
Sbjct: 653 IPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGR 712

Query: 315 SLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAI 374
           + T                         L   + +   +L +++S  ST++  +   P  
Sbjct: 713 TSTST-----------------------LLHTSVESEANLHSSSSTFSTTSSTVSAPP-- 747

Query: 375 DIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGGFTPS-----PVAQP 429
            + S  SS NS S L   L      T        ST S VA+T G   P+     P   P
Sbjct: 748 PVVSVSSSLNSGSSLGLSLGSNSTVT-------ASTRSSVATTSGKAPPNLPPGVPPLLP 800

Query: 430 HP 431
           +P
Sbjct: 801 NP 802


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 33.5 bits (75), Expect = 0.59
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 14/98 (14%)

Query: 344  KELAKKPHT-SLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFH 402
            KEL   P T S  T+ SP S       T P +D     S+ +  S+ P+       P+ H
Sbjct: 1096 KELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDP-----SPSPH 1150

Query: 403  PSV--------HPMSTASQVASTWGGFTPSPVAQPHPS 432
            P+          P++T +   +     TP P   PHP+
Sbjct: 1151 PTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPT 1188



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 6/85 (7%)

Query: 349  KPHTSLTTAASPVSTSAGGIMTA-PAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHP 407
            +P T++    +P ST+     T  P     ST     +T+  P       QPT  P  HP
Sbjct: 1223 QPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQP---FTTMQPTTMP--HP 1277

Query: 408  MSTASQVASTWGGFTPSPVAQPHPS 432
             +T     +     TP P   PHP+
Sbjct: 1278 TTTPHPTTTPHPTTTPHPTTTPHPT 1302


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 33.5 bits (75), Expect = 0.59
 Identities = 48/174 (27%), Positives = 65/174 (37%), Gaps = 16/174 (9%)

Query: 351  HTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMST 410
            HTSL     P +  AG     PA ++ +   S       PN +       F  +  PM  
Sbjct: 2486 HTSLGAGGFPAALPAG-----PAGELHAKVPSGQP----PNFVRSPGTGAFVGTPSPMRF 2536

Query: 411  ASQVASTWGGFTPSPVAQPH--PSAGLNVDF---ESVFGNKSTNVIVDSGGFDELGGLLK 465
                A       P PV QP   P  G+N  F    ++   +STN  V +G F   G  L 
Sbjct: 2537 TFPQAVGEPSLKP-PVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLG 2595

Query: 466  PTVASQNQNLPVAKL-PPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPG 518
            P+  S  ++  ++ L PPS L     D SL  L       +G T        PG
Sbjct: 2596 PSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPG 2649


>gi|11641239 hypothetical protein LOC53838 [Homo sapiens]
          Length = 449

 Score = 33.5 bits (75), Expect = 0.59
 Identities = 81/342 (23%), Positives = 125/342 (36%), Gaps = 38/342 (11%)

Query: 271 PSSLLDALEQHLASLE---GKKIKDST-AASRATTLSNAVSSLASTGLSLTKVDEREKQA 326
           P+ +   L +  AS+E    K  +D T AA+   TL+   S+     + +T  D      
Sbjct: 30  PNKMWKGLVKRNASVETVDNKTSEDVTMAAASPVTLTKGTSAAHLNSMEVTTEDTSRTDV 89

Query: 327 ALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNST 386
           +    +          +  +A     S TTAAS   T+A   MT  +    +  SS+   
Sbjct: 90  S----EPATSGGAADGVTSIAPTAVASSTTAAS--ITTAASSMTVASSAPTTAASSTTVA 143

Query: 387 SKLPNDLLDLQQPTFHPSVHPMSTASQV-ASTWGGFTPSPVAQPHPSAGLNVDFESVFGN 445
           S  P             S  PM+ A     ST  G TPS  A  HPS  L+     V   
Sbjct: 144 SIAPTTAASSMTAA---SSTPMTLALPAPTSTSTGRTPSTTATGHPS--LSTALAQV--- 195

Query: 446 KSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLP-PSKLVSDDLDSSLANLVGNLGIG 504
             ++ +  +     L    +    + N + P++  P PSK +  D  +S    +     G
Sbjct: 196 PKSSALPRTATLATLATRAQTVATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQAQG 255

Query: 505 NGTTKNDVNWSQP----GEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPA 560
                + V+  QP      K     SN  P+ APT      T      P  +P  +  P 
Sbjct: 256 ---PISQVSVDQPVVNTTNKSTPMPSNTTPEPAPTPTVVTTTKAQAREPTASP--VPVPH 310

Query: 561 TTPTGMIGYGIPPQMGSVPVMTQPT-LIYSQPVMRPPNPFGP 601
           T+P         P+M ++   TQP+ + Y+Q    P     P
Sbjct: 311 TSPI--------PEMEAMSPTTQPSPMPYTQRAAGPGTSQAP 344


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,388,607
Number of Sequences: 37866
Number of extensions: 1045578
Number of successful extensions: 4243
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 4073
Number of HSP's gapped (non-prelim): 317
length of query: 610
length of database: 18,247,518
effective HSP length: 108
effective length of query: 502
effective length of database: 14,157,990
effective search space: 7107310980
effective search space used: 7107310980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.