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Search of human proteins with 56786136
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56786136 sperm-specific sodium proton exchanger [Homo
sapiens]
(1177 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens] 2328 0.0
gi|224465231 solute carrier family 9, member 11 [Homo sapiens] 492 e-139
gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)... 65 3e-10
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),... 63 2e-09
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I... 61 7e-09
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I... 61 7e-09
gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),... 60 1e-08
gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo... 59 3e-08
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)... 58 6e-08
gi|192807298 calcium channel, voltage-dependent, L type, alpha 1... 55 3e-07
gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens] 55 5e-07
gi|237512982 voltage-gated sodium channel type V alpha isoform f... 53 2e-06
gi|37622907 voltage-gated sodium channel type V alpha isoform a ... 53 2e-06
gi|30089970 voltage-gated sodium channel type V alpha isoform b ... 53 2e-06
gi|150417969 voltage-gated sodium channel type V alpha isoform d... 53 2e-06
gi|150417967 voltage-gated sodium channel type V alpha isoform c... 53 2e-06
gi|239748090 PREDICTED: similar to sodium channel, voltage-gated... 53 2e-06
gi|20070163 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H... 52 3e-06
gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H... 52 3e-06
gi|38505292 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505290 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505288 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505286 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505284 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505282 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505280 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505278 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505276 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
gi|38505274 voltage-dependent calcium channel alpha 1G subunit i... 52 3e-06
>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
Length = 1177
Score = 2328 bits (6034), Expect = 0.0
Identities = 1177/1177 (100%), Positives = 1177/1177 (100%)
Query: 1 MAGIFKEFFFSTEDLPEVILTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFT 60
MAGIFKEFFFSTEDLPEVILTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFT
Sbjct: 1 MAGIFKEFFFSTEDLPEVILTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFT 60
Query: 61 SSQVQRYANAIQWMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYI 120
SSQVQRYANAIQWMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYI
Sbjct: 61 SSQVQRYANAIQWMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYI 120
Query: 121 LVLWHLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSV 180
LVLWHLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSV
Sbjct: 121 LVLWHLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSV 180
Query: 181 ISLITFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTVFGD 240
ISLITFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTVFGD
Sbjct: 181 ISLITFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTVFGD 240
Query: 241 DVNHISLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEETLLLEFWTFLSR 300
DVNHISLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEETLLLEFWTFLSR
Sbjct: 241 DVNHISLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEETLLLEFWTFLSR 300
Query: 301 IAFLMVFTFFGLLIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSRVGHEFS 360
IAFLMVFTFFGLLIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSRVGHEFS
Sbjct: 301 IAFLMVFTFFGLLIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSRVGHEFS 360
Query: 361 WRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITLVVNRFILP 420
WRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITLVVNRFILP
Sbjct: 361 WRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITLVVNRFILP 420
Query: 421 VAVTILGLRDATSTKYKSVCCTFQHFQELTKSAASALKFDKDLANADWNMIEKAITLENP 480
VAVTILGLRDATSTKYKSVCCTFQHFQELTKSAASALKFDKDLANADWNMIEKAITLENP
Sbjct: 421 VAVTILGLRDATSTKYKSVCCTFQHFQELTKSAASALKFDKDLANADWNMIEKAITLENP 480
Query: 481 YMLNEEETTEHQKVKCPHCNKEIDEIFNTEAMELANRRLLSAQIASYQRQYRNEILSQSA 540
YMLNEEETTEHQKVKCPHCNKEIDEIFNTEAMELANRRLLSAQIASYQRQYRNEILSQSA
Sbjct: 481 YMLNEEETTEHQKVKCPHCNKEIDEIFNTEAMELANRRLLSAQIASYQRQYRNEILSQSA 540
Query: 541 VQVLVGAAESFGEKKGKCMSLDTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGPSKYFF 600
VQVLVGAAESFGEKKGKCMSLDTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGPSKYFF
Sbjct: 541 VQVLVGAAESFGEKKGKCMSLDTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGPSKYFF 600
Query: 601 FRICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEAL 660
FRICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEAL
Sbjct: 601 FRICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEAL 660
Query: 661 LKIAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRIL 720
LKIAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRIL
Sbjct: 661 LKIAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRIL 720
Query: 721 RIFKLIAPKLLQIIDKRMSHQKTFWYGILKGYVQGEADIMTIIDQITSSKQIKQMLLKQV 780
RIFKLIAPKLLQIIDKRMSHQKTFWYGILKGYVQGEADIMTIIDQITSSKQIKQMLLKQV
Sbjct: 721 RIFKLIAPKLLQIIDKRMSHQKTFWYGILKGYVQGEADIMTIIDQITSSKQIKQMLLKQV 780
Query: 781 IRNMEHAIKELGYLEYDHPEIAVTVKTKEEINVMLNMATEILKAFGLKGIISKTEGAGIN 840
IRNMEHAIKELGYLEYDHPEIAVTVKTKEEINVMLNMATEILKAFGLKGIISKTEGAGIN
Sbjct: 781 IRNMEHAIKELGYLEYDHPEIAVTVKTKEEINVMLNMATEILKAFGLKGIISKTEGAGIN 840
Query: 841 KLIMAKKKEVLDSQSIIRPLTVEEVLYHIPWLDKNKDYINFIQEKAKVVTFDCGNDIFEE 900
KLIMAKKKEVLDSQSIIRPLTVEEVLYHIPWLDKNKDYINFIQEKAKVVTFDCGNDIFEE
Sbjct: 841 KLIMAKKKEVLDSQSIIRPLTVEEVLYHIPWLDKNKDYINFIQEKAKVVTFDCGNDIFEE 900
Query: 901 GDEPKGIYIIISGMVKLEKSKPGLGIDQMVESKEKDFPIIDTDYMLSGEIIGEINCLTNE 960
GDEPKGIYIIISGMVKLEKSKPGLGIDQMVESKEKDFPIIDTDYMLSGEIIGEINCLTNE
Sbjct: 901 GDEPKGIYIIISGMVKLEKSKPGLGIDQMVESKEKDFPIIDTDYMLSGEIIGEINCLTNE 960
Query: 961 PMKYSATCKTVVETCFIPKTHLYDAFEQCSPLIKQKMWLKLGLAITARKIREHLSYEDWN 1020
PMKYSATCKTVVETCFIPKTHLYDAFEQCSPLIKQKMWLKLGLAITARKIREHLSYEDWN
Sbjct: 961 PMKYSATCKTVVETCFIPKTHLYDAFEQCSPLIKQKMWLKLGLAITARKIREHLSYEDWN 1020
Query: 1021 YNMQLKLSNIYVVDIPMSTKTDIYDENLIYVILIHGAVEDCLLRKTYRAPFLIPITCHQI 1080
YNMQLKLSNIYVVDIPMSTKTDIYDENLIYVILIHGAVEDCLLRKTYRAPFLIPITCHQI
Sbjct: 1021 YNMQLKLSNIYVVDIPMSTKTDIYDENLIYVILIHGAVEDCLLRKTYRAPFLIPITCHQI 1080
Query: 1081 QSIEDFTKVVIIQTPINMKTFRRNIRKFVPKHKSYLTPGLIGSVGTLEEGIQEERNVKED 1140
QSIEDFTKVVIIQTPINMKTFRRNIRKFVPKHKSYLTPGLIGSVGTLEEGIQEERNVKED
Sbjct: 1081 QSIEDFTKVVIIQTPINMKTFRRNIRKFVPKHKSYLTPGLIGSVGTLEEGIQEERNVKED 1140
Query: 1141 GAHSAATARSPQPCSLLGTKFNCKESPRINLRKVRKE 1177
GAHSAATARSPQPCSLLGTKFNCKESPRINLRKVRKE
Sbjct: 1141 GAHSAATARSPQPCSLLGTKFNCKESPRINLRKVRKE 1177
>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
Length = 1124
Score = 492 bits (1267), Expect = e-139
Identities = 316/1080 (29%), Positives = 570/1080 (52%), Gaps = 45/1080 (4%)
Query: 28 IGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLFFRIFTPVV 87
+G L L++ + V IL L G +++ S +V + + S + F+P++
Sbjct: 41 LGGLLKMCLKNCEVIVLTILSLSGFVIGHMAYNSVEVHQIVYPLLRTSSFSLYSYFSPLI 100
Query: 88 FFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASVNQLLLKPTQWLLFSAILV 147
F A D++ Y L+K+FWQ+LL + F I++ + + N+ LLFS L
Sbjct: 101 IFMVALDVEFYTLKKMFWQVLLTGLISFSTASIIIGYVVIKFNKDSWDLQSCLLFSITLG 160
Query: 148 SSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFDQRLQSKRNHTLAEE 207
DP+ + +++ +G+S+ I LI GESL+ I+ I F + ++ + ++ +
Sbjct: 161 IIDPLRSVNSLKTIGISKIYIDLIRGESLIICSIASIFFGNFRG------NRIHFSIFRD 214
Query: 208 IVGGI-CSY-IIASFLFGILSSKLIQFWMSTVFGDDVNHISLIFSILYLIFYICELVGMS 265
+ GI SY I+ S +FG +K+IQ ++ VF + + +I L FS++Y+ FYI E +GMS
Sbjct: 215 LHVGIELSYDILGSIIFGYWCAKIIQCILADVFSNMLTNIILCFSMVYMTFYIVEFLGMS 274
Query: 266 GIFTLAIVGLLLNSTSFKAAIEETLLLEFWTFLSRIAFLMVFTFFGLLIPAHTYLYIEFV 325
G LA VGL L+S +FK IE ++ +F S + +++ FFG++I + EF
Sbjct: 275 GTLALAAVGLNLDSLTFKPKIE-LVITKFLRIFSSVYEHLIYAFFGIVIGCGELSHYEFH 333
Query: 326 DIYYSLNIYLTLIVLRFLTLLLISPVLSRVGHEFSWRWIFIMVCSEMKGMPNINMALLLA 385
I + ++ T+ ++R LT+LL+SP+L +E++WRW ++ S +KG+ N LL
Sbjct: 334 TIPFIFILFTTVNLVRLLTILLVSPILMHSNYEYNWRWGVVITWSGIKGVFN-----LLW 388
Query: 386 YSDLYFGSDKE---KSQILFHGVLVCLITLVVNRFILPVAVTILGLRDATSTKYKSVCCT 442
D+Y ++++ + + ++ L+T+ +N +++ + L L + + +
Sbjct: 389 APDVYNLAERKVEVPQMFILYVQVISLLTMGINSYVMTQSARKLDLCVLSLPRQMILQNA 448
Query: 443 FQHFQELTKSAASALKFDKDLANADWNMIEKAITLEN-PYMLNEEETTEHQKVKCPHCNK 501
QH QE+ ++ + K +K L N +W ++E +E P+ H +
Sbjct: 449 TQHIQEIVQNTITLFKTEKILTNVNWTLVEDKTRIEYIPFS------------HVSHNDM 496
Query: 502 EIDEIFNTEAMELANRRLLSAQIASYQRQYRNEILSQSAVQVLVGAAESFGEKKGKCMSL 561
+ + + ME A + + Q++S+++Q N IL A ++L+GAA+ + +GK MS+
Sbjct: 497 KTESTTDEALMEEARLHVAAIQMSSFEKQRNNGILEIEAARILIGAAKCYYSIQGKFMSI 556
Query: 562 DTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGP--SKYFFFRICHTIVFTEEFEHVGYL 619
+ Y ++ + + +L Y K P S F I H IVF+EEFE+ G +
Sbjct: 557 YDVSTYMRTRSWLIKFKNVLTFLEYCIEKIHFIPPESNTFLTFIFH-IVFSEEFEYTGQI 615
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMRKDFFSHAWNIFE 679
+ L+ I+P II + S L NY F+ LY+LE+ LKI +++ +F WN E
Sbjct: 616 INLIYIYPMIIHLWPMARGLNVSALISINYYFMFLYVLESTLKIIILKRKYFQQCWNTLE 675
Query: 680 LAITLIGILHVILIEIDTIK----YIFNETEVIVFIKVVQFFRILRIFKLIAPKLLQIID 735
I +IGI+ + + ++ + T ++ ++++++F L +FK+I P L++I D
Sbjct: 676 FFILVIGIIDIFCVYFVKLRPDNLALIQLTVIMGYLRIIRF---LPLFKIIVPILIRIAD 732
Query: 736 KRMSHQKTFWYGILKGYVQGEADIMTIIDQITSSKQIKQMLLKQVIRNMEHAIKELGYLE 795
++ + + Y I KGY++ + D +I QI + I Q L + + N + A+KEL +E
Sbjct: 733 VQIKKRLSLMYSITKGYIKSQEDAKLLIKQIAVCESIYQKLCEILETNKQDAVKELVLME 792
Query: 796 YDHPEIAVTVKTKEEINVMLNMATEILKAFGLKGIISKTEGAGINKLIMAKKKEVLDSQS 855
++ ++ + +KTK+ I ++ A + L +GII K E INK+++ K K + +
Sbjct: 793 HEGRDVVIALKTKQAIRNVIAKALKNLTFLCSRGIIDKHEVIEINKVLLKKLKALNNFPK 852
Query: 856 IIRPLTVEEVLYHIPWLDKNKDYINFIQEKAKVVTFDCGNDIFEEGDEPKGIYIIISGMV 915
I P T + L++I WL+ I+F +E+AK+ FD G+ I + G+ P+GIY+IISGM
Sbjct: 853 AIPPPTPDIYLHNIIWLEGKDVLIDFFKERAKLACFDSGDTICKGGEMPQGIYLIISGMA 912
Query: 916 KLEKSKPGLGID--QMVESKEKDFPIIDTDYMLSGEIIGEINCLTNEPMKYSATCKTVVE 973
L P GI+ Q + +D + T++ +G+IIGE++CL ++Y+ C+T ++
Sbjct: 913 ILHSLSPTFGIESNQRCDRGSRD---MFTEFCTTGDIIGELSCLLKREIEYTVICETSLQ 969
Query: 974 TCFIPKTHLYDAFEQCSPLIKQKMWLKLGLAITARKIREHLSYEDWNYNMQLKLSNIYVV 1033
CFI LY+ F+ P ++ K+WLKL L+ + L ED + + + YV
Sbjct: 970 ACFISLEDLYEGFDAFWPSLEYKIWLKLALSTAYQYFESSLIDEDLRFQNCVMFNQAYVE 1029
Query: 1034 DIPMSTKTDIYDENLIYVILIHGAVEDCLLRKTYRAPFLIPITCHQIQSIEDFTKVVIIQ 1093
+ + I + + +VI+++G+V D + Y AP +IP TC Q+Q D +K++IIQ
Sbjct: 1030 TLSSYSDMIIDNMTMKFVIIVYGSVIDTKTEEPYFAPCIIPTTCEQVQGTSDLSKLLIIQ 1089
>gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 3 [Homo sapiens]
Length = 834
Score = 65.5 bits (158), Expect = 3e-10
Identities = 75/360 (20%), Positives = 146/360 (40%), Gaps = 34/360 (9%)
Query: 16 PEVILTLSLISSIG--AFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQW 73
P VI L++S+ F H +P +L +LG + + + + +
Sbjct: 55 PYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFT----- 109
Query: 74 MSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASV---- 129
++P +FF P + + M + ILL ++ G + N L V
Sbjct: 110 LTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSG 169
Query: 130 --NQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFT 187
L + +LLF +++ + DP+ A ++ ++ L ++ GESL+ ++++ +
Sbjct: 170 LMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYN 229
Query: 188 SIMDFDQRLQSKRNHTLAEEIVGGICSYIIASFLFGILSSKLIQFWMSTV--FGDDVNHI 245
F+ + ++ + V GI S+ + S L G L + F +S V F V I
Sbjct: 230 V---FESFVALGGDNVTGVDCVKGIVSFFVVS-LGGTLVGVVFAFLLSLVTRFTKHVRII 285
Query: 246 --SLIFSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEE---TLLLEFWTFLSR 300
+F I YL + E++ +S I + G+ KA I E T + L+
Sbjct: 286 EPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQK-YVKANISEQSATTVRYTMKMLAS 344
Query: 301 IAFLMVFTFFGLLI---------PAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPV 351
A ++F F G+ A L + F+ +Y ++ + L +L ++ + P+
Sbjct: 345 SAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPI 404
>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
member 2 [Homo sapiens]
Length = 812
Score = 62.8 bits (151), Expect = 2e-09
Identities = 75/350 (21%), Positives = 147/350 (42%), Gaps = 35/350 (10%)
Query: 20 LTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLF 79
+ L+ ++ IG L L +P +L ++G + F + A M D+F
Sbjct: 88 ILLASLAKIGFHLYHKLPTI-VPESCLLIMVGLLLGGIIFGVDEKSPPA-----MKTDVF 141
Query: 80 FRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASVNQLL------ 133
F P + + M T + I ++ G L N I + L + Q+
Sbjct: 142 FLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSD 201
Query: 134 LKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFD 193
+ Q LLF +++ + DP+ A ++ ++ L L+ GESL+ ++++ + F
Sbjct: 202 ITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSF- 260
Query: 194 QRLQSKRNHTLAEEIVGGICSYI---IASFLFGILSSKLIQFWMSTVFGDDVNHISLIFS 250
Q K T+ ++ GI ++ I L GI + F +T F ++ I +F
Sbjct: 261 --CQMKTIETI--DVFAGIANFFVVGIGGVLIGIFLGFIAAF--TTRFTHNIRVIEPLFV 314
Query: 251 IL--YLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEE--TLLLEFWTFLSRIAFLMV 306
L YL + E+ +SGI + + +N + ++ T + F LS ++ ++
Sbjct: 315 FLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLI 374
Query: 307 FTFFGLLIPAHTYLY--------IEFVDIYYSLNIY-LTLIVLRFLTLLL 347
F F G+ + + + F ++ +L ++ LT ++ RF T+ L
Sbjct: 375 FIFMGVSTVGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRTIPL 424
>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform b [Homo sapiens]
Length = 2188
Score = 60.8 bits (146), Expect = 7e-09
Identities = 37/144 (25%), Positives = 73/144 (50%), Gaps = 8/144 (5%)
Query: 589 RKEKEGPSKYFFFRICHTIVFTEEFEHVGYL------VILMNIFPFIISWISQLNVIYHS 642
+K ++ ++ CHT + YL +I +N+ + +Q + +
Sbjct: 1424 KKRRKAQRLPYYATYCHTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSL-ET 1482
Query: 643 ELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIFELAITLIGILHVILIEIDTIKYI 701
LK+ NY F T+++LEA+LK+ A + FF WN +LAI L+ ++ + L EI+ +
Sbjct: 1483 ALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAAL 1542
Query: 702 FNETEVIVFIKVVQFFRILRIFKL 725
+I ++V++ R+L++ K+
Sbjct: 1543 PINPTIIRIMRVLRIARVLKLLKM 1566
Score = 37.4 bits (85), Expect = 0.085
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 19/107 (17%)
Query: 644 LKHTNYCFLTLYILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIF 702
L+ N F +++ LE +LK+AA D+ + +NIF+ I +I I ++
Sbjct: 637 LEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIV----------- 685
Query: 703 NETEVIVFIKVVQFFRILRIFKLI--APKL---LQIIDKRMSHQKTF 744
+ + V++ FR+LR+ KL+ P L L ++ K M + TF
Sbjct: 686 --GQADGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATF 730
Score = 35.8 bits (81), Expect = 0.25
Identities = 33/165 (20%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 592 KEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWIS-QLNVIYHSEL 644
+E S Y F FR+ C TI+ + F++V I +N + + L
Sbjct: 1110 REDWSVYLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFL 1169
Query: 645 KHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEIDTIK 699
+NY F +++ E LK+ ++ + + +WN+ + + + I+ +++
Sbjct: 1170 TVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASA-- 1227
Query: 700 YIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+++ ++V++ R LR ++I AP L +++ +S K
Sbjct: 1228 ---GGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLK 1269
>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform a [Homo sapiens]
Length = 2223
Score = 60.8 bits (146), Expect = 7e-09
Identities = 37/144 (25%), Positives = 73/144 (50%), Gaps = 8/144 (5%)
Query: 589 RKEKEGPSKYFFFRICHTIVFTEEFEHVGYL------VILMNIFPFIISWISQLNVIYHS 642
+K ++ ++ CHT + YL +I +N+ + +Q + +
Sbjct: 1459 KKRRKAQRLPYYATYCHTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSL-ET 1517
Query: 643 ELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIFELAITLIGILHVILIEIDTIKYI 701
LK+ NY F T+++LEA+LK+ A + FF WN +LAI L+ ++ + L EI+ +
Sbjct: 1518 ALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAAL 1577
Query: 702 FNETEVIVFIKVVQFFRILRIFKL 725
+I ++V++ R+L++ K+
Sbjct: 1578 PINPTIIRIMRVLRIARVLKLLKM 1601
Score = 37.4 bits (85), Expect = 0.085
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 19/107 (17%)
Query: 644 LKHTNYCFLTLYILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIF 702
L+ N F +++ LE +LK+AA D+ + +NIF+ I +I I ++
Sbjct: 672 LEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIV----------- 720
Query: 703 NETEVIVFIKVVQFFRILRIFKLI--APKL---LQIIDKRMSHQKTF 744
+ + V++ FR+LR+ KL+ P L L ++ K M + TF
Sbjct: 721 --GQADGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATF 765
Score = 35.8 bits (81), Expect = 0.25
Identities = 33/165 (20%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 592 KEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWIS-QLNVIYHSEL 644
+E S Y F FR+ C TI+ + F++V I +N + + L
Sbjct: 1145 REDWSVYLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFL 1204
Query: 645 KHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEIDTIK 699
+NY F +++ E LK+ ++ + + +WN+ + + + I+ +++
Sbjct: 1205 TVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASA-- 1262
Query: 700 YIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+++ ++V++ R LR ++I AP L +++ +S K
Sbjct: 1263 ---GGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLK 1304
>gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),
member 9 [Homo sapiens]
Length = 645
Score = 60.1 bits (144), Expect = 1e-08
Identities = 71/361 (19%), Positives = 148/361 (40%), Gaps = 41/361 (11%)
Query: 76 PDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILV----------LWH 125
P++FF + P + F + + + IL + G ++ I++ + H
Sbjct: 131 PEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMIH 190
Query: 126 LASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLIT 185
+ T L F +++ ++DP+ A +L + L +L+ GES++ ++++
Sbjct: 191 AGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVL 250
Query: 186 FTSIMDFDQRLQSKRNHTLA-EEIVGGICSYIIASFLFG----ILSSKLIQFWMSTVFGD 240
SI + + A + VG SF G I+++ L +F F
Sbjct: 251 TYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEF-- 308
Query: 241 DVNHISLIFSILYLIFYICELVGMSGIFTLAIVGL-----LLNSTSFKAAIEETLLLEFW 295
+ L F + + F E G++GI + G+ N+ S + I L EF
Sbjct: 309 PMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFM 368
Query: 296 TFLSRIAFLMVFTFFGL-LIPAHTYLYIEFVDIYYSLNIYLTLIVLRFLTLLLISPVLSR 354
FL A ++F + GL L +++ + + L +L + V R + +S +L+
Sbjct: 369 NFL---AENVIFCYMGLALFTFQNHIF----NALFILGAFLAIFVARACNIYPLSFLLN- 420
Query: 355 VG--HEFSWRWIFIMVCSEMKGMPNINMALLLAYSDLYFGSDKEKSQILFHGVLVCLITL 412
+G + W + +M+ S ++G +A++ ++ + Q++F L+ +
Sbjct: 421 LGRKQKIPWNFQHMMMFSGLRG--------AIAFALAIRNTESQPKQMMFTTTLLLVFFT 472
Query: 413 V 413
V
Sbjct: 473 V 473
>gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo
sapiens]
Length = 1791
Score = 58.9 bits (141), Expect = 3e-08
Identities = 34/143 (23%), Positives = 75/143 (52%), Gaps = 1/143 (0%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAM 666
IV ++ F+ + +I++N+ + +Q + S L H N+ F+ ++ LE L+KI A+
Sbjct: 1362 IVTSQIFDIIIISLIILNMISMMAESYNQPKAM-KSILDHLNWVFVVIFTLECLIKIFAL 1420
Query: 667 RKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKLI 726
R+ +F++ WN+F+ + L+ I+ ++ ++ ++I + +++ + RILR+ +
Sbjct: 1421 RQYYFTNGWNLFDCVVVLLSIVSTMISTLENQEHIPFPPTLFRIVRLARIGRILRLVRAA 1480
Query: 727 APKLLQIIDKRMSHQKTFWYGIL 749
+ MS F G+L
Sbjct: 1481 RGIRTLLFALMMSLPSLFNIGLL 1503
Score = 40.8 bits (94), Expect = 0.008
Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 608 VFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR 667
V T+ F + + ++ F+ ++ + L N F +++I E LKI A+
Sbjct: 573 VMTDPFTELAITICIIINTVFLAMEHHKMEASFEKMLNIGNLVFTSIFIAEMCLKIIALD 632
Query: 668 K-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+F WNIF+ + L+ V+ + + F ++ FR+LR+FKL
Sbjct: 633 PYHYFRRGWNIFDSIVALLSFADVMNCVLQKRSWPF-----------LRSFRVLRVFKL 680
>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
member 4 [Homo sapiens]
Length = 798
Score = 57.8 bits (138), Expect = 6e-08
Identities = 67/311 (21%), Positives = 133/311 (42%), Gaps = 33/311 (10%)
Query: 20 LTLSLISSIGAFLNRHLEDFPIPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLF 79
+ L+ ++ IG L L +P +L L+G + F + + M ++
Sbjct: 77 ILLASLAKIGFHLYHRLPGL-MPESCLLILVGALVGGIIFGTDH-----KSPPVMDSSIY 130
Query: 80 FRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYI---LVLWHLASVNQLLLKP 136
F P + + M T + IL ++ G L+N + L L+ + V L
Sbjct: 131 FLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLICQVKAFGLGD 190
Query: 137 T---QWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFD 193
Q LLF +++ + DP+ A + ++ L +I GE+L+ I+++ + ++ F
Sbjct: 191 VNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFT 250
Query: 194 QRLQSKRNHTLAEEIVGGICSYIIASF---LFGILSSKLIQFWMSTVFGDDVNHIS--LI 248
+ + + T+ +I+ G +I+ LFGI+ + F T F +++ I ++
Sbjct: 251 KMHKFEDIETV--DILAGCARFIVVGLGGVLFGIVFGFISAF--ITRFTQNISAIEPLIV 306
Query: 249 FSILYLIFYICELVGMSGIFTLAIVGLLLNSTSFKAAIEE-------TLLLEFWTFLSRI 301
F YL + E + +SGI + + + K +EE T + F LS +
Sbjct: 307 FMFSYLSYLAAETLYLSGILAITAC-----AVTMKKYVEENVSQTSYTTIKYFMKMLSSV 361
Query: 302 AFLMVFTFFGL 312
+ ++F F G+
Sbjct: 362 SETLIFIFMGV 372
>gi|192807298 calcium channel, voltage-dependent, L type, alpha 1D
subunit isoform c [Homo sapiens]
Length = 2137
Score = 55.5 bits (132), Expect = 3e-07
Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 20/177 (11%)
Query: 552 GEKKGKCMSLDTIKNYSESQKTVTFARKLLLNWVYNTRKEKEGPSKYFFFRICHTIVFTE 611
GEK+ K LD KN + + AR L R + P +Y F+ + V +
Sbjct: 1159 GEKEYKNCELD--KNQRQCVEYALKARPL-------RRYIPKNPYQYKFWYV----VNSS 1205
Query: 612 EFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDF 670
FE++ +++I++N + Q + +++ + N F ++ +E +LK+ A + K +
Sbjct: 1206 PFEYMMFVLIMLNTLCLAMQHYEQ-SKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGY 1264
Query: 671 FSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKLIA 727
FS AWN F+ I + I+ V L E D +E + I + FR++R+ KL++
Sbjct: 1265 FSDAWNTFDSLIVIGSIIDVALSEADN-----SEESNRISITFFRLFRVMRLVKLLS 1316
Score = 37.0 bits (84), Expect = 0.11
Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 602 RICHTIVFTEEFEHVGYLVILMNIFPFIISWI----SQLNVIYHSELKHTNYCFLTLYIL 657
R C +IV + F+ L I N I +I N H+ L+ Y FL ++ +
Sbjct: 117 RACISIVEWKPFDIFILLAIFANCVALAI-YIPFPEDDSNSTNHN-LEKVEYAFLIIFTV 174
Query: 658 EALLKIAAMR-----KDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVI---V 709
E LKI A + + WN+ + I ++G+ VIL ++ N +
Sbjct: 175 ETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGF 234
Query: 710 FIKVVQFFRILRIFKLIA 727
+K ++ FR+LR +L++
Sbjct: 235 DVKALRAFRVLRPLRLVS 252
>gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]
Length = 815
Score = 54.7 bits (130), Expect = 5e-07
Identities = 54/258 (20%), Positives = 109/258 (42%), Gaps = 30/258 (11%)
Query: 73 WMSPDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVN--------YILVLW 124
++ D+FF P + + + + IL+ ++ G L N Y + L
Sbjct: 155 FLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLV 214
Query: 125 HLASVNQLLLKPTQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLI 184
+N + L LLF +I+ + DP+ A ++ ++ L L+ GESL+ ++++
Sbjct: 215 GGEQINNIGLLDN--LLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVV 272
Query: 185 TFTSIMDFDQRLQSKRNHTLAEEIVGGICSYIIASF---LFGILSSKLIQFWMSTVFGDD 241
+ +F + H +I G S+ + + L G++ + F ++ F
Sbjct: 273 LYHLFEEF-----ANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAF--TSRFTSH 325
Query: 242 VNHISLIFSIL--YLIFYICELVGMSGIFTLAIVGLLLN-----STSFKAAIEETLLLEF 294
+ I +F L Y+ + EL +SGI L G+++ + S K+ L+
Sbjct: 326 IRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKM 385
Query: 295 WTFLSRIAFLMVFTFFGL 312
W S ++ ++F F G+
Sbjct: 386 W---SSVSETLIFIFLGV 400
>gi|237512982 voltage-gated sodium channel type V alpha isoform f
[Homo sapiens]
Length = 1962
Score = 52.8 bits (125), Expect = 2e-06
Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQ----LNVIYHSELKHTNYCFLTLYILEALLK 662
IV + F+ +I +N+ ++ Q +N+ L N F+ ++ E ++K
Sbjct: 1470 IVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINI-----LAKINLLFVAIFTGECIVK 1524
Query: 663 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 722
+AA+R +F+++WNIF+ + ++ I+ +L +I KY F+ T +V++ RI RI
Sbjct: 1525 LAALRHYYFTNSWNIFDFVVVILSIVGTVLSDI-IQKYFFSPT----LFRVIRLARIGRI 1579
Query: 723 FKLI 726
+LI
Sbjct: 1580 LRLI 1583
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 640 YHSELKHTNYCFLTLYILEALLKIAAMRKDF-FSHAWNIFELAITLIGILHVILIEIDTI 698
+ L+ N F ++ E KI A+ + F WNIF+ I ++ ++ + L +
Sbjct: 745 FEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSN- 803
Query: 699 KYIFNETEVIVFIKVVQFFRILRIFKL 725
+ V++ FR+LR+FKL
Sbjct: 804 ------------LSVLRSFRLLRVFKL 818
>gi|37622907 voltage-gated sodium channel type V alpha isoform a [Homo
sapiens]
Length = 2016
Score = 52.8 bits (125), Expect = 2e-06
Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQ----LNVIYHSELKHTNYCFLTLYILEALLK 662
IV + F+ +I +N+ ++ Q +N+ L N F+ ++ E ++K
Sbjct: 1524 IVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINI-----LAKINLLFVAIFTGECIVK 1578
Query: 663 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 722
+AA+R +F+++WNIF+ + ++ I+ +L +I KY F+ T +V++ RI RI
Sbjct: 1579 LAALRHYYFTNSWNIFDFVVVILSIVGTVLSDI-IQKYFFSPT----LFRVIRLARIGRI 1633
Query: 723 FKLI 726
+LI
Sbjct: 1634 LRLI 1637
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 640 YHSELKHTNYCFLTLYILEALLKIAAMRKDF-FSHAWNIFELAITLIGILHVILIEIDTI 698
+ L+ N F ++ E KI A+ + F WNIF+ I ++ ++ + L +
Sbjct: 745 FEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSN- 803
Query: 699 KYIFNETEVIVFIKVVQFFRILRIFKL 725
+ V++ FR+LR+FKL
Sbjct: 804 ------------LSVLRSFRLLRVFKL 818
>gi|30089970 voltage-gated sodium channel type V alpha isoform b [Homo
sapiens]
Length = 2015
Score = 52.8 bits (125), Expect = 2e-06
Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQ----LNVIYHSELKHTNYCFLTLYILEALLK 662
IV + F+ +I +N+ ++ Q +N+ L N F+ ++ E ++K
Sbjct: 1523 IVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINI-----LAKINLLFVAIFTGECIVK 1577
Query: 663 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 722
+AA+R +F+++WNIF+ + ++ I+ +L +I KY F+ T +V++ RI RI
Sbjct: 1578 LAALRHYYFTNSWNIFDFVVVILSIVGTVLSDI-IQKYFFSPT----LFRVIRLARIGRI 1632
Query: 723 FKLI 726
+LI
Sbjct: 1633 LRLI 1636
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 640 YHSELKHTNYCFLTLYILEALLKIAAMRKDF-FSHAWNIFELAITLIGILHVILIEIDTI 698
+ L+ N F ++ E KI A+ + F WNIF+ I ++ ++ + L +
Sbjct: 745 FEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSN- 803
Query: 699 KYIFNETEVIVFIKVVQFFRILRIFKL 725
+ V++ FR+LR+FKL
Sbjct: 804 ------------LSVLRSFRLLRVFKL 818
>gi|150417969 voltage-gated sodium channel type V alpha isoform d
[Homo sapiens]
Length = 1998
Score = 52.8 bits (125), Expect = 2e-06
Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQ----LNVIYHSELKHTNYCFLTLYILEALLK 662
IV + F+ +I +N+ ++ Q +N+ L N F+ ++ E ++K
Sbjct: 1506 IVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINI-----LAKINLLFVAIFTGECIVK 1560
Query: 663 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 722
+AA+R +F+++WNIF+ + ++ I+ +L +I KY F+ T +V++ RI RI
Sbjct: 1561 LAALRHYYFTNSWNIFDFVVVILSIVGTVLSDI-IQKYFFSPT----LFRVIRLARIGRI 1615
Query: 723 FKLI 726
+LI
Sbjct: 1616 LRLI 1619
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 640 YHSELKHTNYCFLTLYILEALLKIAAMRKDF-FSHAWNIFELAITLIGILHVILIEIDTI 698
+ L+ N F ++ E KI A+ + F WNIF+ I ++ ++ + L +
Sbjct: 745 FEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSN- 803
Query: 699 KYIFNETEVIVFIKVVQFFRILRIFKL 725
+ V++ FR+LR+FKL
Sbjct: 804 ------------LSVLRSFRLLRVFKL 818
>gi|150417967 voltage-gated sodium channel type V alpha isoform c
[Homo sapiens]
Length = 2016
Score = 52.8 bits (125), Expect = 2e-06
Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQ----LNVIYHSELKHTNYCFLTLYILEALLK 662
IV + F+ +I +N+ ++ Q +N+ L N F+ ++ E ++K
Sbjct: 1524 IVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINI-----LAKINLLFVAIFTGECIVK 1578
Query: 663 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 722
+AA+R +F+++WNIF+ + ++ I+ +L +I KY F+ T +V++ RI RI
Sbjct: 1579 LAALRHYYFTNSWNIFDFVVVILSIVGTVLSDI-IQKYFFSPT----LFRVIRLARIGRI 1633
Query: 723 FKLI 726
+LI
Sbjct: 1634 LRLI 1637
Score = 35.0 bits (79), Expect = 0.42
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 640 YHSELKHTNYCFLTLYILEALLKIAAMRKDF-FSHAWNIFELAITLIGILHVILIEIDTI 698
+ L+ N F ++ E KI A+ + F WNIF+ I ++ ++ + L +
Sbjct: 745 FEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSN- 803
Query: 699 KYIFNETEVIVFIKVVQFFRILRIFKL 725
+ V++ FR+LR+FKL
Sbjct: 804 ------------LSVLRSFRLLRVFKL 818
>gi|239748090 PREDICTED: similar to sodium channel, voltage-gated,
type V, alpha (long QT syndrome 3) [Homo sapiens]
Length = 1637
Score = 52.8 bits (125), Expect = 2e-06
Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 14/124 (11%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQ----LNVIYHSELKHTNYCFLTLYILEALLK 662
IV + F+ +I +N+ ++ Q +N+ L N F+ ++ E ++K
Sbjct: 1133 IVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINI-----LAKINLLFVAIFTGECIVK 1187
Query: 663 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 722
+AA+R +F+++WNIF+ + ++ I+ +L +I KY F+ T +V++ RI RI
Sbjct: 1188 LAALRHYYFTNSWNIFDFVVVILSIVGTVLSDI-IQKYFFSPT----LFRVIRLARIGRI 1242
Query: 723 FKLI 726
+LI
Sbjct: 1243 LRLI 1246
>gi|20070163 voltage-dependent calcium channel alpha 1G subunit
isoform 1 [Homo sapiens]
Length = 2377
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1620 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1678
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1679 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1725
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1250 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1306
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1307 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1366
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1367 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1410
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|53832011 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform b [Homo sapiens]
Length = 2347
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 2/125 (1%)
Query: 602 RICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALL 661
R H++ + + +I +N+ + +Q + + LK+ NY F +++ EA L
Sbjct: 1602 RSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEA-LKYCNYVFTIVFVFEAAL 1660
Query: 662 KIAAMR-KDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRIL 720
K+ A + FF WN +LAI L+ ++ + L EI+ + +I ++V++ R+L
Sbjct: 1661 KLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVL 1720
Query: 721 RIFKL 725
++ K+
Sbjct: 1721 KLLKM 1725
Score = 37.4 bits (85), Expect = 0.085
Identities = 30/164 (18%), Positives = 73/164 (44%), Gaps = 19/164 (11%)
Query: 590 KEKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWIS-QLNVIYHS 642
+ +E + Y F FR+ C ++ + F+HV + I +N +
Sbjct: 1267 RSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERV 1326
Query: 643 ELKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEIDT 697
L +NY F +++ E ++K+ A+ + +WN+ + + L+ ++ +++
Sbjct: 1327 FLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASA 1386
Query: 698 IKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMS 739
+++ ++V++ R LR ++I AP L +++ +S
Sbjct: 1387 -----GGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLIS 1425
Score = 35.0 bits (79), Expect = 0.42
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 20/144 (13%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAM 666
IV ++ F + IL+N + + Q + ++ L+ +N F +++ LE LLK+ A
Sbjct: 789 IVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNA-LEISNIVFTSMFALEMLLKLLAC 847
Query: 667 RK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+ + +NIF+ I +I + ++ + + V++ FR+LR+ KL
Sbjct: 848 GPLGYIRNPYNIFDGIIVVISVWEIV-------------GQADGGLSVLRTFRLLRVLKL 894
Query: 726 I--APKL---LQIIDKRMSHQKTF 744
+ P L L ++ K M + TF
Sbjct: 895 VRFLPALRRQLVVLVKTMDNVATF 918
>gi|53832009 calcium channel, voltage-dependent, T type, alpha 1H
subunit isoform a [Homo sapiens]
Length = 2353
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/125 (24%), Positives = 64/125 (51%), Gaps = 2/125 (1%)
Query: 602 RICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALL 661
R H++ + + +I +N+ + +Q + + LK+ NY F +++ EA L
Sbjct: 1608 RSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEA-LKYCNYVFTIVFVFEAAL 1666
Query: 662 KIAAMR-KDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRIL 720
K+ A + FF WN +LAI L+ ++ + L EI+ + +I ++V++ R+L
Sbjct: 1667 KLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVL 1726
Query: 721 RIFKL 725
++ K+
Sbjct: 1727 KLLKM 1731
Score = 37.4 bits (85), Expect = 0.085
Identities = 30/164 (18%), Positives = 73/164 (44%), Gaps = 19/164 (11%)
Query: 590 KEKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWIS-QLNVIYHS 642
+ +E + Y F FR+ C ++ + F+HV + I +N +
Sbjct: 1267 RSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERV 1326
Query: 643 ELKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEIDT 697
L +NY F +++ E ++K+ A+ + +WN+ + + L+ ++ +++
Sbjct: 1327 FLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASA 1386
Query: 698 IKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMS 739
+++ ++V++ R LR ++I AP L +++ +S
Sbjct: 1387 -----GGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLIS 1425
Score = 35.0 bits (79), Expect = 0.42
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 20/144 (13%)
Query: 607 IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAM 666
IV ++ F + IL+N + + Q + ++ L+ +N F +++ LE LLK+ A
Sbjct: 789 IVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNA-LEISNIVFTSMFALEMLLKLLAC 847
Query: 667 RK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+ + +NIF+ I +I + ++ + + V++ FR+LR+ KL
Sbjct: 848 GPLGYIRNPYNIFDGIIVVISVWEIV-------------GQADGGLSVLRTFRLLRVLKL 894
Query: 726 I--APKL---LQIIDKRMSHQKTF 744
+ P L L ++ K M + TF
Sbjct: 895 VRFLPALRRQLVVLVKTMDNVATF 918
>gi|38505292 voltage-dependent calcium channel alpha 1G subunit
isoform 3 [Homo sapiens]
Length = 2343
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1586 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1644
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1645 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1691
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1227 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1283
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1284 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1343
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1344 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1387
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505290 voltage-dependent calcium channel alpha 1G subunit
isoform 13 [Homo sapiens]
Length = 2243
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1579 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1637
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1638 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1684
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1227 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1283
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1284 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1343
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1344 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1387
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505288 voltage-dependent calcium channel alpha 1G subunit
isoform 12 [Homo sapiens]
Length = 2250
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1586 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1644
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1645 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1691
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1227 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1283
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1284 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1343
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1344 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1387
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505286 voltage-dependent calcium channel alpha 1G subunit
isoform 10 [Homo sapiens]
Length = 2266
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1602 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1660
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1661 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1707
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1250 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1306
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1307 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1366
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1367 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1410
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505284 voltage-dependent calcium channel alpha 1G subunit
isoform 4 [Homo sapiens]
Length = 2332
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1620 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1678
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1679 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1725
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1250 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1306
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1307 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1366
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1367 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1410
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505282 voltage-dependent calcium channel alpha 1G subunit
isoform 8 [Homo sapiens]
Length = 2284
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1620 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1678
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1679 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1725
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1250 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1306
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1307 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1366
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1367 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1410
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505280 voltage-dependent calcium channel alpha 1G subunit
isoform 6 [Homo sapiens]
Length = 2306
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1597 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1655
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1656 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1702
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1227 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1283
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1284 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1343
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1344 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1387
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505278 voltage-dependent calcium channel alpha 1G subunit
isoform 11 [Homo sapiens]
Length = 2261
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1597 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1655
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1656 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1702
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1227 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1283
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1284 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1343
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1344 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1387
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505276 voltage-dependent calcium channel alpha 1G subunit
isoform 5 [Homo sapiens]
Length = 2321
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1609 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1667
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1668 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1714
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1250 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1306
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1307 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1366
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1367 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1410
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
>gi|38505274 voltage-dependent calcium channel alpha 1G subunit
isoform 7 [Homo sapiens]
Length = 2298
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 620 VILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLKIAAMR-KDFFSHAWNIF 678
VI +N+ + Q ++ + LK NY F +++LE++ K+ A + FF WN
Sbjct: 1586 VIGLNVVTMAMEHYQQPQILDEA-LKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQL 1644
Query: 679 ELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRIFKL 725
+LAI L+ I+ + L EI+ + +I ++V++ R+L++ K+
Sbjct: 1645 DLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKM 1691
Score = 48.5 bits (114), Expect = 4e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 25/169 (14%)
Query: 591 EKEGPSKYFF-----FRI-CHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSE- 643
E++ S Y F FR+ CH I+ + F+HV ++I +N I + + + HS
Sbjct: 1227 ERDSWSAYIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNC---ITIAMERPKIDPHSAE 1283
Query: 644 ---LKHTNYCFLTLYILEALLKIAAM-----RKDFFSHAWNIFELAITLIGILHVILIEI 695
L +NY F +++ E +K+ A+ + + +WN+ + + LI ++ +++ +
Sbjct: 1284 RIFLTLSNYIFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMV 1343
Query: 696 DTIKYIFNETEVIVFIKVVQFFRILRIFKLI--APKLLQIIDKRMSHQK 742
+ T+++ ++V++ R LR ++I A L +++ MS K
Sbjct: 1344 SD-----SGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLK 1387
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/155 (23%), Positives = 71/155 (45%), Gaps = 23/155 (14%)
Query: 599 FFFRICHT---IVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLY 655
F+ IC T IV ++ F + IL+N I + Q + ++ L+ +N F +L+
Sbjct: 728 FWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNA-LEISNIVFTSLF 786
Query: 656 ILEALLKIAAMRK-DFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVV 714
LE LLK+ + + +NIF+ I +I + ++ + + V+
Sbjct: 787 ALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLS-------------VL 833
Query: 715 QFFRILRIFKLI-----APKLLQIIDKRMSHQKTF 744
+ FR++R+ KL+ + L ++ K M + TF
Sbjct: 834 RTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATF 868
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,538,686
Number of Sequences: 37866
Number of extensions: 1593324
Number of successful extensions: 5283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 4898
Number of HSP's gapped (non-prelim): 335
length of query: 1177
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1064
effective length of database: 13,968,660
effective search space: 14862654240
effective search space used: 14862654240
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.