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Search of human proteins with 56550049
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56550049 uromodulin precursor [Homo sapiens]
(640 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56550049 uromodulin precursor [Homo sapiens] 1365 0.0
gi|59850812 uromodulin precursor [Homo sapiens] 1365 0.0
gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2 [... 545 e-155
gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1 [... 539 e-153
gi|119220573 zymogen granule membrane glycoprotein 2 isoform 4 [... 372 e-103
gi|119220572 zymogen granule membrane glycoprotein 2 isoform 3 [... 372 e-103
gi|134268640 tectorin alpha precursor [Homo sapiens] 214 1e-55
gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens] 190 4e-48
gi|66346695 fibrillin 2 precursor [Homo sapiens] 112 8e-25
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 110 4e-24
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 110 4e-24
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 110 4e-24
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 110 4e-24
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 110 4e-24
gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens] 107 3e-23
gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens] 107 3e-23
gi|118572606 hemicentin 1 [Homo sapiens] 103 6e-22
gi|24430141 fibrillin 1 precursor [Homo sapiens] 102 8e-22
gi|42476320 sushi domain containing 1 [Homo sapiens] 102 1e-21
gi|110347437 latent transforming growth factor beta binding prot... 101 2e-21
gi|110347412 latent transforming growth factor beta binding prot... 101 2e-21
gi|110347431 latent transforming growth factor beta binding prot... 101 2e-21
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 101 2e-21
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 100 4e-21
gi|56237021 fibrillin 3 precursor [Homo sapiens] 97 3e-20
gi|40807489 egf-like module containing, mucin-like, hormone rece... 97 3e-20
gi|144953895 nidogen 2 precursor [Homo sapiens] 97 6e-20
gi|46249414 latent transforming growth factor beta binding prote... 95 2e-19
gi|46249412 latent transforming growth factor beta binding prote... 95 2e-19
gi|4557733 latent transforming growth factor beta binding protei... 95 2e-19
>gi|56550049 uromodulin precursor [Homo sapiens]
Length = 640
Score = 1365 bits (3533), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDG 60
MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDG
Sbjct: 1 MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDG 60
Query: 61 LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHC 120
LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHC
Sbjct: 61 LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHC 120
Query: 121 HALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTL 180
HALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTL
Sbjct: 121 HALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTL 180
Query: 181 DEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDE 240
DEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDE
Sbjct: 181 DEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDE 240
Query: 241 GIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC 300
GIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC
Sbjct: 241 GIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC 300
Query: 301 SIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMY 360
SIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMY
Sbjct: 301 SIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMY 360
Query: 361 LSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIK 420
LSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIK
Sbjct: 361 LSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIK 420
Query: 421 INFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLS 480
INFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLS
Sbjct: 421 INFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLS 480
Query: 481 TEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVEN 540
TEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVEN
Sbjct: 481 TEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVEN 540
Query: 541 GESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLN 600
GESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLN
Sbjct: 541 GESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLN 600
Query: 601 LGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ 640
LGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ
Sbjct: 601 LGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ 640
>gi|59850812 uromodulin precursor [Homo sapiens]
Length = 640
Score = 1365 bits (3533), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDG 60
MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDG
Sbjct: 1 MGQPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDG 60
Query: 61 LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHC 120
LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHC
Sbjct: 61 LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHC 120
Query: 121 HALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTL 180
HALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTL
Sbjct: 121 HALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTL 180
Query: 181 DEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDE 240
DEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDE
Sbjct: 181 DEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDE 240
Query: 241 GIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC 300
GIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC
Sbjct: 241 GIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC 300
Query: 301 SIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMY 360
SIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMY
Sbjct: 301 SIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMY 360
Query: 361 LSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIK 420
LSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIK
Sbjct: 361 LSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIK 420
Query: 421 INFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLS 480
INFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLS
Sbjct: 421 INFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLS 480
Query: 481 TEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVEN 540
TEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVEN
Sbjct: 481 TEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVEN 540
Query: 541 GESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLN 600
GESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLN
Sbjct: 541 GESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLN 600
Query: 601 LGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ 640
LGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ
Sbjct: 601 LGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ 640
>gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2
[Homo sapiens]
Length = 534
Score = 545 bits (1403), Expect = e-155
Identities = 274/526 (52%), Positives = 355/526 (67%), Gaps = 16/526 (3%)
Query: 122 ALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEG--DALVCADPCQAHRT 179
AL +C+ L A RG G E S S G LDC G +A VC DPCQ +
Sbjct: 17 ALVSCI------LTQASAVQRGYGNPIEAS--SYGLDLDCGAPGTPEAHVCFDPCQNYTL 68
Query: 180 LDEYWRSTEYGEG-YACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSS 238
LDE +RSTE G CD ++ GWYRFVG+GG RM+ETCV V RC T APMWLNGTHP+
Sbjct: 69 LDEPFRSTENSAGSQGCDKNMSGWYRFVGEGGVRMSETCVQVHRCQTDAPMWLNGTHPAL 128
Query: 239 DEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCE 298
+GI + ACAHWSG+CC W V VKAC GGY+VY L P C+L YCTDPS+VE CE
Sbjct: 129 GDGITNHTACAHWSGNCCFWKTEVLVKACPGGYHVYRLEGTPWCNLRYCTDPSTVEDKCE 188
Query: 299 E-CSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGF-DK 356
+ C +E+C + N W C C+QD N +D+ L+ +L+CG ++KV + KC L LG ++
Sbjct: 189 KACRPEEECLALNSTWGCFCRQDLNSSDVHSLQPQLDCGPREIKVKVDKCLLGGLGLGEE 248
Query: 357 VFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRD 416
V YL D CS + R+WVSV +P + C +L RN+THA Y NTL L ++ IIRD
Sbjct: 249 VIAYLRDPNCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTLSLVNDFIIRD 308
Query: 417 LNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSS 476
+ INF C+YPLDMKVSL+ ALQP+VS+LN+ V G G F VRMALFQ +YT PY+G +
Sbjct: 309 TILNINFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDA 368
Query: 477 VTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQ 536
V LS E+ LYVG +L+ GD SRF L++ NCYATP+ + D +KYFII++ C + RDSTI
Sbjct: 369 VELSVESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDSTIH 428
Query: 537 VVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSG-SVIDQ 595
V ENG+SS+ RFSVQMF FAG+YDLV+LHCE++LCD++NE+C+P+CS ++ RS ID
Sbjct: 429 VEENGQSSESRFSVQMFMFAGHYDLVFLHCEIHLCDSLNEQCQPSCSRSQVRSEVPAIDL 488
Query: 596 SRVLNLGPITRKGVQA--TVSRAFSSLGLLKVWLPLLLSATLTLTF 639
+RVL+LGPITR+G Q+ ++ S+ G L W +LL+ L F
Sbjct: 489 ARVLDLGPITRRGAQSPGVMNGTPSTAGFLVAWPMVLLTVLLAWLF 534
>gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1
[Homo sapiens]
Length = 537
Score = 539 bits (1389), Expect = e-153
Identities = 274/529 (51%), Positives = 355/529 (67%), Gaps = 19/529 (3%)
Query: 122 ALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEG--DALVCADPCQAHRT 179
AL +C+ L A RG G E S S G LDC G +A VC DPCQ +
Sbjct: 17 ALVSCI------LTQASAVQRGYGNPIEAS--SYGLDLDCGAPGTPEAHVCFDPCQNYTL 68
Query: 180 LDEYWRSTEYGEG-YACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSS 238
LDE +RSTE G CD ++ GWYRFVG+GG RM+ETCV V RC T APMWLNGTHP+
Sbjct: 69 LDEPFRSTENSAGSQGCDKNMSGWYRFVGEGGVRMSETCVQVHRCQTDAPMWLNGTHPAL 128
Query: 239 DEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCT---DPSSVEG 295
+GI + ACAHWSG+CC W V VKAC GGY+VY L P C+L YCT DPS+VE
Sbjct: 129 GDGITNHTACAHWSGNCCFWKTEVLVKACPGGYHVYRLEGTPWCNLRYCTVPRDPSTVED 188
Query: 296 TCEE-CSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGF 354
CE+ C +E+C + N W C C+QD N +D+ L+ +L+CG ++KV + KC L LG
Sbjct: 189 KCEKACRPEEECLALNSTWGCFCRQDLNSSDVHSLQPQLDCGPREIKVKVDKCLLGGLGL 248
Query: 355 -DKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEII 413
++V YL D CS + R+WVSV +P + C +L RN+THA Y NTL L ++ I
Sbjct: 249 GEEVIAYLRDPNCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTLSLVNDFI 308
Query: 414 IRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQ 473
IRD + INF C+YPLDMKVSL+ ALQP+VS+LN+ V G G F VRMALFQ +YT PY+
Sbjct: 309 IRDTILNINFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYE 368
Query: 474 GSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDS 533
G +V LS E+ LYVG +L+ GD SRF L++ NCYATP+ + D +KYFII++ C + RDS
Sbjct: 369 GDAVELSVESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDS 428
Query: 534 TIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSG-SV 592
TI V ENG+SS+ RFSVQMF FAG+YDLV+LHCE++LCD++NE+C+P+CS ++ RS
Sbjct: 429 TIHVEENGQSSESRFSVQMFMFAGHYDLVFLHCEIHLCDSLNEQCQPSCSRSQVRSEVPA 488
Query: 593 IDQSRVLNLGPITRKGVQA--TVSRAFSSLGLLKVWLPLLLSATLTLTF 639
ID +RVL+LGPITR+G Q+ ++ S+ G L W +LL+ L F
Sbjct: 489 IDLARVLDLGPITRRGAQSPGVMNGTPSTAGFLVAWPMVLLTVLLAWLF 537
>gi|119220573 zymogen granule membrane glycoprotein 2 isoform 4
[Homo sapiens]
Length = 387
Score = 372 bits (955), Expect = e-103
Identities = 183/356 (51%), Positives = 249/356 (69%), Gaps = 5/356 (1%)
Query: 289 DPSSVEGTCEE-CSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKC 347
DPS+VE CE+ C +E+C + N W C C+QD N +D+ L+ +L+CG ++KV + KC
Sbjct: 32 DPSTVEDKCEKACRPEEECLALNSTWGCFCRQDLNSSDVHSLQPQLDCGPREIKVKVDKC 91
Query: 348 QLKSLGF-DKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTL 406
L LG ++V YL D CS + R+WVSV +P + C +L RN+THA Y NTL
Sbjct: 92 LLGGLGLGEEVIAYLRDPNCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTL 151
Query: 407 YLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTP 466
L ++ IIRD + INF C+YPLDMKVSL+ ALQP+VS+LN+ V G G F VRMALFQ
Sbjct: 152 SLVNDFIIRDTILNINFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQ 211
Query: 467 SYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDR 526
+YT PY+G +V LS E+ LYVG +L+ GD SRF L++ NCYATP+ + D +KYFII++
Sbjct: 212 NYTNPYEGDAVELSVESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNS 271
Query: 527 CPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTR 586
C + RDSTI V ENG+SS+ RFSVQMF FAG+YDLV+LHCE++LCD++NE+C+P+CS ++
Sbjct: 272 CSNQRDSTIHVEENGQSSESRFSVQMFMFAGHYDLVFLHCEIHLCDSLNEQCQPSCSRSQ 331
Query: 587 FRSG-SVIDQSRVLNLGPITRKGVQA--TVSRAFSSLGLLKVWLPLLLSATLTLTF 639
RS ID +RVL+LGPITR+G Q+ ++ S+ G L W +LL+ L F
Sbjct: 332 VRSEVPAIDLARVLDLGPITRRGAQSPGVMNGTPSTAGFLVAWPMVLLTVLLAWLF 387
>gi|119220572 zymogen granule membrane glycoprotein 2 isoform 3
[Homo sapiens]
Length = 390
Score = 372 bits (955), Expect = e-103
Identities = 183/356 (51%), Positives = 249/356 (69%), Gaps = 5/356 (1%)
Query: 289 DPSSVEGTCEE-CSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKC 347
DPS+VE CE+ C +E+C + N W C C+QD N +D+ L+ +L+CG ++KV + KC
Sbjct: 35 DPSTVEDKCEKACRPEEECLALNSTWGCFCRQDLNSSDVHSLQPQLDCGPREIKVKVDKC 94
Query: 348 QLKSLGF-DKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTL 406
L LG ++V YL D CS + R+WVSV +P + C +L RN+THA Y NTL
Sbjct: 95 LLGGLGLGEEVIAYLRDPNCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTL 154
Query: 407 YLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTP 466
L ++ IIRD + INF C+YPLDMKVSL+ ALQP+VS+LN+ V G G F VRMALFQ
Sbjct: 155 SLVNDFIIRDTILNINFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQ 214
Query: 467 SYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDR 526
+YT PY+G +V LS E+ LYVG +L+ GD SRF L++ NCYATP+ + D +KYFII++
Sbjct: 215 NYTNPYEGDAVELSVESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNS 274
Query: 527 CPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTR 586
C + RDSTI V ENG+SS+ RFSVQMF FAG+YDLV+LHCE++LCD++NE+C+P+CS ++
Sbjct: 275 CSNQRDSTIHVEENGQSSESRFSVQMFMFAGHYDLVFLHCEIHLCDSLNEQCQPSCSRSQ 334
Query: 587 FRSG-SVIDQSRVLNLGPITRKGVQA--TVSRAFSSLGLLKVWLPLLLSATLTLTF 639
RS ID +RVL+LGPITR+G Q+ ++ S+ G L W +LL+ L F
Sbjct: 335 VRSEVPAIDLARVLDLGPITRRGAQSPGVMNGTPSTAGFLVAWPMVLLTVLLAWLF 390
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 214 bits (546), Expect = 1e-55
Identities = 116/334 (34%), Positives = 186/334 (55%), Gaps = 18/334 (5%)
Query: 289 DPSSVEGTCEECSIDEDCKSN-----NGRWHCQCKQD--FNITDISLLEHRLECGANDMK 341
+ + G E+ + DC + NGR C C + + +++ + C A M+
Sbjct: 1753 EKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDIIDAEVTCKAAQME 1812
Query: 342 VSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHAT 401
VS+ KC+L LGF++ + ++D +C+G + D++S G CG ++ N TH
Sbjct: 1813 VSISKCKLFQLGFEREGVRINDRQCTGI---EGEDFISFQINNTKGNCGNIVQSNGTHIM 1869
Query: 402 YSNTLYLAD-----EIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRVGGT-GM 455
Y NTL++ II RD I + F+C+Y LD+K+SL + ++PM+S +N+ V G
Sbjct: 1870 YKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGS 1929
Query: 456 FTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNAT 515
F +MAL++ SY PY+ V L+T LYVG + G D + L + CYATP+ ++
Sbjct: 1930 FITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKCYATPTRDSN 1989
Query: 516 DPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMN 575
D L+YFII+ C + +D+TI + EN S RF V +F+F G+YD V+LHC V LCD+
Sbjct: 1990 DKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEK 2049
Query: 576 EKCKPTC-SGTRFRSGSVID-QSRVLNLGPITRK 607
CK TC +R + + + +++++GPI RK
Sbjct: 2050 YSCKITCPHNSRIATDYTKEPKEQIISVGPIRRK 2083
Score = 30.8 bits (68), Expect = 4.0
Identities = 32/123 (26%), Positives = 42/123 (34%), Gaps = 23/123 (18%)
Query: 34 ECHSNA------TCTE------------DEAVTTCTCQEGFTGDGLTCVDLDECAIP-GA 74
EC N+ TCTE D C C EG+ G CV EC
Sbjct: 983 ECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEG 1042
Query: 75 HNCSANSS-CVNTPGSFSCVC--PEGFRLSPGLGCTDVDECAEP-GLSHCHALATCVNVV 130
H + N + V+ C C + + C D + C E GL +C A +V
Sbjct: 1043 HQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIV 1102
Query: 131 GSY 133
Y
Sbjct: 1103 SGY 1105
>gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]
Length = 545
Score = 190 bits (482), Expect = 4e-48
Identities = 148/535 (27%), Positives = 226/535 (42%), Gaps = 114/535 (21%)
Query: 169 VCADPCQAHRTLDEYWRSTEYGEGYA-----CDTDLRG-WYRFVGQGGARMAETCVPVLR 222
V DPC A+ +L+E WR+T++ + CD + G WY F G G M C+P
Sbjct: 20 VALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENH 79
Query: 223 CNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPEC 282
C T AP+WLNG+HP +GIV R+ACA ++G+CCLW+ +V+VKAC GGYYVY LT P C
Sbjct: 80 CGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVC 139
Query: 283 HLAYC-------------TDPSSVEGTC----------EECSIDEDCKSNNGRWHCQCKQ 319
YC + + E TC + C + +C+ NNG C
Sbjct: 140 FHVYCGHFYDICDEDCHGSCSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVN 199
Query: 320 DFNITDISLLEHRLECGANDMKVSLGK--------------CQLKSLGFDKVF------- 358
N +R ECG + S GK C LG +K +
Sbjct: 200 LKN-------SYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRG 252
Query: 359 ----------------------------------MYLSDSRCSGFNDRDNRDWVSVVTPA 384
++L+++ C G + N V+++
Sbjct: 253 LVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVS---NGTHVNILFSL 309
Query: 385 RDGPCGTVLTRNETHATYSN--------TLYLADEIIIRDLNIKINFACSYPLDMKVSLK 436
+ CGTV+ SN T + + IIR + I C +P +S
Sbjct: 310 K--TCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEG 367
Query: 437 TALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDL 496
S L I G+F + +F+ + +PY+ + TL LY G + +
Sbjct: 368 YVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFG-IEPVVHV 426
Query: 497 SRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFA 556
S L+ +C+ATP+S + LKY++I+D C D +++ + + F V +F+F
Sbjct: 427 SGLESLVESCFATPTSKIDEVLKYYLIRDGC--VSDDSVKQYTSRDHLAKHFQVPVFKFV 484
Query: 557 G-NYDLVYLHCEVYLCDTMNE--KCKPTCSGTRFRSGSVID----QSRVLNLGPI 604
G ++ V+LHC V +C ++E +C C R D Q + L GPI
Sbjct: 485 GKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAGGEDSAGLQGQTLTGGPI 539
Score = 37.4 bits (85), Expect = 0.043
Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 80 NSSCVNTPGSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSYLCVCP 138
+ SC +T C C G L P C D +EC E C + CVN+ SY C C
Sbjct: 156 HGSCSDTS---ECTCAPGTVLGPDRQTCFDENEC-EQNNGGCSEI--CVNLKNSYRCECG 209
Query: 139 AG--YRGDGWHCE----CSPGSCGPGLDCVPEGDALVCADP 173
G R DG CE C + G C+ C P
Sbjct: 210 VGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECP 250
Score = 36.6 bits (83), Expect = 0.073
Identities = 30/104 (28%), Positives = 41/104 (39%), Gaps = 17/104 (16%)
Query: 33 SECHSN-----ATCTEDEAVTTCTCQEG--FTGDGLTCVDLDECAIPGAHNCSANSSCVN 85
+EC N C + C C G DG TC D++ C +N + SC+
Sbjct: 184 NECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCH---NNNGGCSHSCLG 240
Query: 86 TPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNV 129
+ + C CP G LS D C P L C + A VN+
Sbjct: 241 SEKGYQCECPRGLVLS-----EDNHTCQVPVL--CKSNAIEVNI 277
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 112 bits (281), Expect = 8e-25
Identities = 55/123 (44%), Positives = 72/123 (58%), Gaps = 5/123 (4%)
Query: 20 TTAATDTSEAR-WCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCS 78
TT TD E C +A+C C+C+EG+ G+G+ C+DLDEC+ G H CS
Sbjct: 1362 TTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECS-NGTHQCS 1420
Query: 79 ANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCP 138
N+ CVNTPGS+ C C EGF G C+DVDECAE ++ C C+NV G+Y C C
Sbjct: 1421 INAQCVNTPGSYRCACSEGF-TGDGFTCSDVDECAE-NINLCEN-GQCLNVPGAYRCECE 1477
Query: 139 AGY 141
G+
Sbjct: 1478 MGF 1480
Score = 105 bits (263), Expect = 1e-22
Identities = 91/330 (27%), Positives = 130/330 (39%), Gaps = 86/330 (26%)
Query: 33 SECHSNAT------CTEDEAVTTCTCQEGFT-GDGLT-CVDLDECAIPGAHNCSANSSCV 84
+EC N+ C + C CQ G++ G T C D+DEC I GAHNC ++SC+
Sbjct: 1327 NECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI-GAHNCDMHASCL 1385
Query: 85 NTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
N PGSF C C EG+ + G+ C D+DEC+ G C A CVN GSY C C G+ GD
Sbjct: 1386 NIPGSFKCSCREGW-IGNGIKCIDLDECSN-GTHQCSINAQCVNTPGSYRCACSEGFTGD 1443
Query: 145 GWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYR 204
G+ C D C + L E + Y C+ ++
Sbjct: 1444 GFTCSD--------------------VDECAENINLCENGQCLNVPGAYRCECEM----- 1478
Query: 205 FVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSG--HCCLWDASV 262
G A + +C + C S + I C + G HC
Sbjct: 1479 --GFTPASDSRSCQDIDEC--------------SFQNICVFGTCNNLPGMFHCI------ 1516
Query: 263 QVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDF- 321
C GY + + T + C DP + ++ C + GR+ C C DF
Sbjct: 1517 ----CDDGYEL-DRTGGNCTDIDECADPINC--------VNGLCVNTPGRYECNCPPDFQ 1563
Query: 322 -NITDISLLEHRLECGANDMKVSLGKCQLK 350
N T + +++R +G C LK
Sbjct: 1564 LNPTGVGCVDNR-----------VGNCYLK 1582
Score = 99.8 bits (247), Expect = 7e-21
Identities = 70/212 (33%), Positives = 96/212 (45%), Gaps = 30/212 (14%)
Query: 34 ECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCV 93
+C NA C C C EGFTGDG TC D+DECA N N C+N PG++ C
Sbjct: 1418 QCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECA--ENINLCENGQCLNVPGAYRCE 1475
Query: 94 CPEGFR-LSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD--GWHC-- 148
C GF S C D+DEC+ + TC N+ G + C+C GY D G +C
Sbjct: 1476 CEMGFTPASDSRSCQDIDECS---FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTD 1532
Query: 149 --ECS-PGSCGPGL----------DCVPEGDALVCADPCQAHRTLDEYWRSTEYGEG-YA 194
EC+ P +C GL +C P+ C +R + Y + G+G +
Sbjct: 1533 IDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLS 1592
Query: 195 CDTDLR-GWYR-----FVGQGGARMAETCVPV 220
C+T++ G R +G+ ETC PV
Sbjct: 1593 CNTEIGVGVSRSSCCCSLGKAWGNPCETCPPV 1624
Score = 97.4 bits (241), Expect = 3e-20
Identities = 87/345 (25%), Positives = 128/345 (37%), Gaps = 66/345 (19%)
Query: 37 SNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
SN C + C C G+ D G+ CVD DEC+I N N +C N GSF C C
Sbjct: 2183 SNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIG---NPCGNGTCTNVIGSFECNC 2239
Query: 95 PEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY--RGDGWHC---- 148
EGF P + C D++ECA+ L C+N GSY C CP GY R D C
Sbjct: 2240 NEGFEPGPMMNCEDINECAQNPLL---CAFRCMNTFGSYECTCPIGYALREDQKMCKDLD 2296
Query: 149 ECSPG--------------------SCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTE 188
EC+ G C PG+ P+G+ V + C+ + E R
Sbjct: 2297 ECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVN 2356
Query: 189 YGEGYACD------TDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEG- 241
Y C+ + G + G AE + + +++ + + D G
Sbjct: 2357 IIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGR 2416
Query: 242 --------------IVSRKACAHWSGHCC----LWDASVQVKACAGGYYVYNL-TAPPEC 282
+K C H G+ + + V C G + + + C
Sbjct: 2417 GWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFC 2476
Query: 283 HLAYCTDPSSVEG-TCEECS-----IDEDCKSNNGRWHCQCKQDF 321
+ Y TD S +ECS + CK+ G + C C + +
Sbjct: 2477 KVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGY 2521
Score = 92.0 bits (227), Expect = 1e-18
Identities = 53/147 (36%), Positives = 71/147 (48%), Gaps = 11/147 (7%)
Query: 20 TTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGL--TCVDLDECAIPGAHNC 77
T A D E + +N C C C GF+ + L C D+DEC+ G + C
Sbjct: 1803 TGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECS-NGDNLC 1861
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
N+ C+N+PGS+ C C GF+LSP C D +EC E H L CV++ GSY C+C
Sbjct: 1862 QRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL--CVDLQGSYQCIC 1919
Query: 138 PAGYRG--DGWHC----ECSPGSCGPG 158
G++ D C EC CG G
Sbjct: 1920 HNGFKASQDQTMCMDVDECERHPCGNG 1946
Score = 89.4 bits (220), Expect = 9e-18
Identities = 70/186 (37%), Positives = 83/186 (44%), Gaps = 34/186 (18%)
Query: 49 TCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCT 107
TC C GFT C+D +EC + C A C NTPGSFSC C GF L + GL C
Sbjct: 2555 TCKCPPGFTQHHTACIDNNECGSQPSL-CGAKGICQNTPGSFSCECQRGFSLDATGLNCE 2613
Query: 108 DVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY-RGDGWH-C----ECS-PGSCGPGLD 160
DVDEC G C C N++G Y C CP GY + W+ C ECS P +CG
Sbjct: 2614 DVDEC--DGNHRCQ--HGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACG-SAS 2668
Query: 161 CVPEGDALVCADP-----------------CQAHRTLDEYWRSTEYGEGYACDTDLRGWY 203
C + CA P C + + Y S G GY C G+Y
Sbjct: 2669 CYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEG-GYLCGCP-PGYY 2726
Query: 204 RFVGQG 209
R VGQG
Sbjct: 2727 R-VGQG 2731
Score = 89.0 bits (219), Expect = 1e-17
Identities = 86/367 (23%), Positives = 136/367 (37%), Gaps = 58/367 (15%)
Query: 24 TDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGL---TCVDLDECAIPGAHNCSAN 80
TD E R + + C C C EG+ + C+D+DEC
Sbjct: 1114 TDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPL--LCRG 1171
Query: 81 SSCVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPA 139
+CVNT GSF C CP G LSP C D++EC+ + CVN++G+Y C C
Sbjct: 1172 GTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLS--DNLCRNGKCVNMIGTYQCSCNP 1229
Query: 140 GYR-------------------GDGWHCECSPG----SCGPGLDCVPEGDALVCADPCQA 176
GY+ G C S G SC G +P+G + CAD
Sbjct: 1230 GYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRS--CAD---- 1283
Query: 177 HRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMA---ETCVPVLRCNTAAPMWLNG 233
+DE + + +G C T++ G YR + G + +TC+ V C+ + + + G
Sbjct: 1284 ---IDECENNPDICDGGQC-TNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFG 1339
Query: 234 THPSSDEGIVSRKACAH-----WSGHCCLWDASVQVKACAGGYYVYNLTAPPECHL---- 284
++ + + +G + + + C N+ +C
Sbjct: 1340 ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW 1399
Query: 285 ----AYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDM 340
C D +CSI+ C + G + C C + F + + EC N
Sbjct: 1400 IGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVD-ECAENIN 1458
Query: 341 KVSLGKC 347
G+C
Sbjct: 1459 LCENGQC 1465
Score = 87.8 bits (216), Expect = 3e-17
Identities = 53/147 (36%), Positives = 70/147 (47%), Gaps = 15/147 (10%)
Query: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTG--DGLTCVDLDECAIPGAHNCSA 79
A D +E S+ C + + C C GF D C+D+DEC H C
Sbjct: 1889 ACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE---RHPCG- 1944
Query: 80 NSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPA 139
N +C NT GS++C+C GF L+ C D+DEC+ C C N +GS+ C+C
Sbjct: 1945 NGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNE 2003
Query: 140 GYR--GDGWHC----EC--SPGSCGPG 158
GY DG +C EC PGSC PG
Sbjct: 2004 GYELTPDGKNCIDTNECVALPGSCSPG 2030
Score = 85.5 bits (210), Expect = 1e-16
Identities = 94/390 (24%), Positives = 137/390 (35%), Gaps = 75/390 (19%)
Query: 20 TTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNC 77
TT D E + +N C C C+ G+T D G +C+DLDEC+ C
Sbjct: 2444 TTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS-QSPKPC 2502
Query: 78 SANSSCVNTPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCV 136
N C NT GS+ C CP G+ L G C D+DEC + +C L CVN +G + C
Sbjct: 2503 --NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDEC-QTKQHNCQFL--CVNTLGGFTCK 2557
Query: 137 CPAGYRG------DGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYG 190
CP G+ D C P CG C + C CQ +LD
Sbjct: 2558 CPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC--ECQRGFSLD--------A 2607
Query: 191 EGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAH 250
G C+ + C RC L G +G + H
Sbjct: 2608 TGLNCED----------------VDECDGNHRCQHGCQNILGGYRCGCPQGYIQ-----H 2646
Query: 251 WSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNN 310
+ + C+ + G YN +C C S + C +C S+
Sbjct: 2647 YQWNQCVDENECSNPNACGSASCYNTLGSYKC---ACPSGFSFDQFSSACHDVNECSSSK 2703
Query: 311 GRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLS-------- 362
C + T+ L C +V G C + +GF+K YLS
Sbjct: 2704 N----PCNYGCSNTEGGYL---CGCPPGYYRVGQGHC-VSGMGFNK-GQYLSLDTEVDEE 2754
Query: 363 ---------DSRCSGFNDRDNRDWVSVVTP 383
+ + +G++ +D+R S+ P
Sbjct: 2755 NALSPEACYECKINGYSKKDSRQKRSIHEP 2784
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/163 (32%), Positives = 70/163 (42%), Gaps = 31/163 (19%)
Query: 38 NATCTEDEAVTTCTCQEGFTGDGL-TCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPE 96
N C + C C G+ D C+D+DEC N N CVNTPGS+ C C
Sbjct: 507 NGRCIPTVSSYRCECNMGYKQDANGDCIDVDECT----SNPCTNGDCVNTPGSYYCKCHA 562
Query: 97 GFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC----E 149
GF+ +P C D+DEC + G+ + CVN GS+ C+C AG+ DG +C E
Sbjct: 563 GFQRTPTKQACIDIDECIQNGVLCKN--GRCVNTDGSFQCICNAGFELTTDGKNCVDHDE 620
Query: 150 CSPGS-----------------CGPGLDCVPEGDALVCADPCQ 175
C+ + C PG P G D CQ
Sbjct: 621 CTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ 663
Score = 79.3 bits (194), Expect = 1e-14
Identities = 83/321 (25%), Positives = 117/321 (36%), Gaps = 54/321 (16%)
Query: 31 WCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCV--DLDECA-IPGAHNCSANSSCVNTP 87
W + C + E T C EGF + +T + D+DEC +PG +C+NT
Sbjct: 1614 WGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGL---CQGGNCINTF 1670
Query: 88 GSFSCVCPEGFRLSPGLG-CTDVDEC-AEPGLSHCHALATCVNVVGSYLCVCPAGYR--G 143
GSF C CP+G+ LS C D+DEC A PG+ TC N +G+Y C+CP Y
Sbjct: 1671 GSFQCECPQGYYLSEDTRICEDIDECFAHPGVC---GPGTCYNTLGNYTCICPPEYMQVN 1727
Query: 144 DGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWY 203
G +C S C + C + + T + C T Y
Sbjct: 1728 GGHNCMDMRKSF-----CYRSYNGTTCENELPFNVT-----------KRMCCCT-----Y 1766
Query: 204 RFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKA-----CAHWSGHC--- 255
G + C P TA + G P I + KA C G C
Sbjct: 1767 NV----GKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANG 1822
Query: 256 -CLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWH 314
C+ C G+ +L L C D C + DC ++ G +
Sbjct: 1823 VCINQIGSFRCECPTGFSYNDL-------LLVCEDIDECSNGDNLCQRNADCINSPGSYR 1875
Query: 315 CQCKQDFNITDISLLEHRLEC 335
C+C F ++ R EC
Sbjct: 1876 CECAAGFKLSPNGACVDRNEC 1896
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/116 (43%), Positives = 60/116 (51%), Gaps = 14/116 (12%)
Query: 52 CQEGFTGDGLT--CVDLDEC-AIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLG-CT 107
C+ GF + T C D+DEC AIPG +C+NT GSF C CP G + S C
Sbjct: 261 CRRGFIPNIRTGACQDVDECQAIPGI---CQGGNCINTVGSFECRCPAGHKQSETTQKCE 317
Query: 108 DVDECAE-PGLSHCHALATCVNVVGSYLCVCPAGY--RGDGWHC-ECSPGSCGPGL 159
D+DEC+ PG+ C N VGSY CVCP GY DG C + G C GL
Sbjct: 318 DIDECSIIPGICET---GECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGL 370
Score = 70.1 bits (170), Expect = 6e-12
Identities = 47/149 (31%), Positives = 64/149 (42%), Gaps = 24/149 (16%)
Query: 19 ITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHN 76
IT D +E + +N C C C G+ D G C+D+DEC +
Sbjct: 762 ITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRL-- 819
Query: 77 CSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
N C NTPGS+SC CP G+ + C D++EC S+ C N +GS+
Sbjct: 820 LCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE----SNPCVNGACRNNLGSF-- 873
Query: 136 VCPAGYRGDGWHCECSPGS--CGPGLDCV 162
+CECSPGS GL C+
Sbjct: 874 -----------NCECSPGSKLSSTGLICI 891
Score = 68.2 bits (165), Expect = 2e-11
Identities = 40/103 (38%), Positives = 52/103 (50%), Gaps = 11/103 (10%)
Query: 50 CTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCTD 108
C G+T DG D+DEC + N N C+NT GSF C C G+ G C D
Sbjct: 2437 CPHGPGYTTDGR---DIDECKV--MPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCID 2491
Query: 109 VDECAEPGLSHCHALATCVNVVGSYLCVCPAGY--RGDGWHCE 149
+DEC++ C+ + C N GSY C CP GY + DG C+
Sbjct: 2492 LDECSQ-SPKPCNYI--CKNTEGSYQCSCPRGYVLQEDGKTCK 2531
Score = 63.5 bits (153), Expect = 6e-10
Identities = 73/305 (23%), Positives = 106/305 (34%), Gaps = 57/305 (18%)
Query: 38 NATCTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCP 95
N C ++ C C+ GF +G C D+DEC PG N C+N+ GSF C CP
Sbjct: 629 NGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGI---CMNGHCINSEGSFRCDCP 685
Query: 96 EGFRLS-PGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGS 154
G + G C D H +TC + +CV P C C+
Sbjct: 686 PGLAVGMDGRVCVDT-----------HMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPD 734
Query: 155 CGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACD-TDLRGWYRFVGQGGARM 213
G G C PC A + E+ G G D D+ +
Sbjct: 735 YGFGEPC----------QPCPAKNSA-EFHGLCSSGVGITVDGRDINECALDPDICANGI 783
Query: 214 AETCVPVLRCNTAAPMWLNGTHPSS--------DEGIVSRKACAHWSGHCCLWDASVQVK 265
E RCN +G P + DE +V+R C +G C S
Sbjct: 784 CENLRGSYRCNCN-----SGYEPDASGRNCIDIDECLVNRLLCD--NGLCRNTPGS---- 832
Query: 266 ACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCE-ECSIDEDCKSNNGRWHCQCKQDFNIT 324
Y+ T PP T+ CE ++ C++N G ++C+C ++
Sbjct: 833 --------YSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLS 884
Query: 325 DISLL 329
L+
Sbjct: 885 STGLI 889
Score = 62.8 bits (151), Expect = 1e-09
Identities = 91/359 (25%), Positives = 117/359 (32%), Gaps = 86/359 (23%)
Query: 29 ARWCSECHSNATCTEDEAVTTCTCQEGFT--GDGLT----CVDLDEC-AIPGAHNCSANS 81
A W +EC E T C GF GD LT D++EC A PG
Sbjct: 1031 AAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGM---CTYG 1087
Query: 82 SCVNTPGSFSCVCPEGFRLS-PGLGCTDVDEC-AEPGLSHCHALATCVNVVGSYLCVCPA 139
C NT GSF C C GF L CTD+DEC P L CVN GS+ C C
Sbjct: 1088 KCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC---GSGICVNTPGSFECECFE 1144
Query: 140 GYRG---------DGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYG 190
GY D CE +P C G EG
Sbjct: 1145 GYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEG------------------------- 1179
Query: 191 EGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLN-------GTHPSS----- 238
+ CD L G + E CV + C+ + + N GT+ S
Sbjct: 1180 -SFQCDCPL-------GHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY 1231
Query: 239 -----DEGIVSRKACAHWSGHC---CLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDP 290
+G C +G C C +C+ GY + P+ C D
Sbjct: 1232 QATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALM-----PDGR--SCADI 1284
Query: 291 SSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNIT-DISLLEHRLECGANDMKVSLGKCQ 348
E + C C + G + C C F + D+ EC N G+C+
Sbjct: 1285 DECENNPDICD-GGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECE 1342
Score = 60.5 bits (145), Expect = 5e-09
Identities = 77/326 (23%), Positives = 104/326 (31%), Gaps = 89/326 (27%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCV 84
DT+E S TC E C C G+ C+D++EC N SC
Sbjct: 2016 DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINEC--DEDPNICLFGSCT 2073
Query: 85 NTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRG 143
NTPG F C+CP GF LS G C D + + C + C P +
Sbjct: 2074 NTPGGFQCLCPPGFVLSDNGRRCFDTRQ------------SFCFTNFENGKCSVPKAFNT 2121
Query: 144 DGWHCECS--PG-SCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLR 200
C CS PG G + P+ D + D C YG G
Sbjct: 2122 TKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLC-------------PYGHG-------- 2160
Query: 201 GWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDA 260
VP L+ T +E + S C+ +G C D
Sbjct: 2161 ----------------TVPS----------LHDTREDVNECLESPGICS--NGQCINTDG 2192
Query: 261 SVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGT-CEECSIDEDCKSNN-----GRWH 314
S + EC + Y D + V +ECSI C + G +
Sbjct: 2193 SFRC----------------ECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFE 2236
Query: 315 CQCKQDFNITDISLLEHRLECGANDM 340
C C + F + E EC N +
Sbjct: 2237 CNCNEGFEPGPMMNCEDINECAQNPL 2262
Score = 56.2 bits (134), Expect = 9e-08
Identities = 91/369 (24%), Positives = 118/369 (31%), Gaps = 92/369 (24%)
Query: 26 TSEARWCSECHSNATCTEDEAVTTCTCQEGFTG-DGLTCVDLDECAI-PGAHNCSANSSC 83
T A W S C C D A C G G+TC D++EC + PG N C
Sbjct: 923 TLGAAWGSPCER---CELDTA-----CPRGLARIKGVTCEDVNECEVFPGV---CPNGRC 971
Query: 84 VNTPGSFSCVCPEGFRL-SPGLGCTDV-----------DECAEPGLSHCHALATCVNV-- 129
VN+ GSF C CPEG L G C D+ DEC P A C V
Sbjct: 972 VNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGA 1031
Query: 130 -------------VGSYLCVCPAG----YRGDGW----------HCECSPGSCGPGLDCV 162
Y +CP G RGD C+ PG C G C
Sbjct: 1032 AWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG-KCR 1090
Query: 163 PEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVG-------------QG 209
+ C C + LD R+ + DL G V +
Sbjct: 1091 NTIGSFKCR--CNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYES 1148
Query: 210 GARMAETCVPVLRCNTAAPMWLNGT-----------HPSSDEGIVSRKACAHWSGHCCLW 258
G M + C+ + C + GT P E SR+ C C L
Sbjct: 1149 GFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD-INECSLS 1207
Query: 259 DASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGT-CEECSI-----DEDCKSNNGR 312
D + C Y + C+ Y P T +EC I D C ++ G
Sbjct: 1208 DNLCRNGKCVNMIGTYQCS----CNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGS 1263
Query: 313 WHCQCKQDF 321
+ C C + +
Sbjct: 1264 YECSCSEGY 1272
Score = 51.6 bits (122), Expect = 2e-06
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 76 NCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
N N C+ T S+ C C G++ C DVDEC ++ CVN GSY C
Sbjct: 503 NLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTN----GDCVNTPGSYYC 558
Query: 136 VCPAGYR 142
C AG++
Sbjct: 559 KCHAGFQ 565
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/165 (24%), Positives = 53/165 (32%), Gaps = 44/165 (26%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGF--TGDGLTCVD----------------- 65
D +E R N C C C EGF + G C+D
Sbjct: 2338 DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQM 2397
Query: 66 ---------LDECAIPGAHNCSANSSCVNTPGS--FSCVCPEGFRLSPGLGC--TDVDEC 112
EC G PG+ + +CP G PG D+DEC
Sbjct: 2398 ASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHG----PGYTTDGRDIDEC 2453
Query: 113 AEPGLSHCHALATCVNVVGSYLCVCPAGYRGD--GWHC----ECS 151
+ + C+N +GS+ C C GY D G C ECS
Sbjct: 2454 KV--MPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS 2496
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 110 bits (275), Expect = 4e-24
Identities = 98/337 (29%), Positives = 135/337 (40%), Gaps = 63/337 (18%)
Query: 31 WCSE---CHSNATCTEDEAVTTCTCQEGFTG---DGLTCVDLDECAIPGAHNCSANSSCV 84
+CSE C N+ C C+C++GF D C D+DECA G H C N+ CV
Sbjct: 423 FCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-EGRHYCRENTMCV 481
Query: 85 NTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
NTPGSF C+C G+ CT+ DEC +C A C N VG + CVC GY G+
Sbjct: 482 NTPGSFMCICKTGYIRIDDYSCTEHDECI-TNQHNCDENALCFNTVGGHNCVCKPGYTGN 540
Query: 145 GWHCE--CSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYA-CDT---- 197
G C+ C G C G C+ A VCA P Q E +G+ CD+
Sbjct: 541 GTTCKAFCKDG-CRNGGACIA---ANVCACP-QGFTGPSCETDIDECSDGFVQCDSRANC 595
Query: 198 -DLRGWYRFVGQGG-------ARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
+L GWY + G + E+C + C T N T + +G + C
Sbjct: 596 INLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCR-CP 654
Query: 250 HWSGHC---CLWDASVQ--------------VKACAGGYYVYNLTAPPECHLAYCTDPSS 292
H +C C+ D V+ V +C G+ + + C +P+
Sbjct: 655 H-GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRM------VCDCENPTV 707
Query: 293 VEGTCEECS--IDEDCKSNNGR--------WHCQCKQ 319
C EC + C NG W C+Q
Sbjct: 708 DLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQ 744
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 110 bits (275), Expect = 4e-24
Identities = 98/337 (29%), Positives = 135/337 (40%), Gaps = 63/337 (18%)
Query: 31 WCSE---CHSNATCTEDEAVTTCTCQEGFTG---DGLTCVDLDECAIPGAHNCSANSSCV 84
+CSE C N+ C C+C++GF D C D+DECA G H C N+ CV
Sbjct: 399 FCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-EGRHYCRENTMCV 457
Query: 85 NTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
NTPGSF C+C G+ CT+ DEC +C A C N VG + CVC GY G+
Sbjct: 458 NTPGSFMCICKTGYIRIDDYSCTEHDECI-TNQHNCDENALCFNTVGGHNCVCKPGYTGN 516
Query: 145 GWHCE--CSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYA-CDT---- 197
G C+ C G C G C+ A VCA P Q E +G+ CD+
Sbjct: 517 GTTCKAFCKDG-CRNGGACIA---ANVCACP-QGFTGPSCETDIDECSDGFVQCDSRANC 571
Query: 198 -DLRGWYRFVGQGG-------ARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
+L GWY + G + E+C + C T N T + +G + C
Sbjct: 572 INLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCR-CP 630
Query: 250 HWSGHC---CLWDASVQ--------------VKACAGGYYVYNLTAPPECHLAYCTDPSS 292
H +C C+ D V+ V +C G+ + + C +P+
Sbjct: 631 H-GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRM------VCDCENPTV 683
Query: 293 VEGTCEECS--IDEDCKSNNGR--------WHCQCKQ 319
C EC + C NG W C+Q
Sbjct: 684 DLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQ 720
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 110 bits (275), Expect = 4e-24
Identities = 98/337 (29%), Positives = 135/337 (40%), Gaps = 63/337 (18%)
Query: 31 WCSE---CHSNATCTEDEAVTTCTCQEGFTG---DGLTCVDLDECAIPGAHNCSANSSCV 84
+CSE C N+ C C+C++GF D C D+DECA G H C N+ CV
Sbjct: 400 FCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-EGRHYCRENTMCV 458
Query: 85 NTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
NTPGSF C+C G+ CT+ DEC +C A C N VG + CVC GY G+
Sbjct: 459 NTPGSFMCICKTGYIRIDDYSCTEHDECI-TNQHNCDENALCFNTVGGHNCVCKPGYTGN 517
Query: 145 GWHCE--CSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYA-CDT---- 197
G C+ C G C G C+ A VCA P Q E +G+ CD+
Sbjct: 518 GTTCKAFCKDG-CRNGGACIA---ANVCACP-QGFTGPSCETDIDECSDGFVQCDSRANC 572
Query: 198 -DLRGWYRFVGQGG-------ARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
+L GWY + G + E+C + C T N T + +G + C
Sbjct: 573 INLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCR-CP 631
Query: 250 HWSGHC---CLWDASVQ--------------VKACAGGYYVYNLTAPPECHLAYCTDPSS 292
H +C C+ D V+ V +C G+ + + C +P+
Sbjct: 632 H-GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRM------VCDCENPTV 684
Query: 293 VEGTCEECS--IDEDCKSNNGR--------WHCQCKQ 319
C EC + C NG W C+Q
Sbjct: 685 DLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQ 721
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 110 bits (275), Expect = 4e-24
Identities = 98/337 (29%), Positives = 135/337 (40%), Gaps = 63/337 (18%)
Query: 31 WCSE---CHSNATCTEDEAVTTCTCQEGFTG---DGLTCVDLDECAIPGAHNCSANSSCV 84
+CSE C N+ C C+C++GF D C D+DECA G H C N+ CV
Sbjct: 450 FCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-EGRHYCRENTMCV 508
Query: 85 NTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
NTPGSF C+C G+ CT+ DEC +C A C N VG + CVC GY G+
Sbjct: 509 NTPGSFMCICKTGYIRIDDYSCTEHDECI-TNQHNCDENALCFNTVGGHNCVCKPGYTGN 567
Query: 145 GWHCE--CSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYA-CDT---- 197
G C+ C G C G C+ A VCA P Q E +G+ CD+
Sbjct: 568 GTTCKAFCKDG-CRNGGACIA---ANVCACP-QGFTGPSCETDIDECSDGFVQCDSRANC 622
Query: 198 -DLRGWYRFVGQGG-------ARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
+L GWY + G + E+C + C T N T + +G + C
Sbjct: 623 INLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCR-CP 681
Query: 250 HWSGHC---CLWDASVQ--------------VKACAGGYYVYNLTAPPECHLAYCTDPSS 292
H +C C+ D V+ V +C G+ + + C +P+
Sbjct: 682 H-GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRM------VCDCENPTV 734
Query: 293 VEGTCEECS--IDEDCKSNNGR--------WHCQCKQ 319
C EC + C NG W C+Q
Sbjct: 735 DLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQ 771
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 110 bits (275), Expect = 4e-24
Identities = 98/337 (29%), Positives = 135/337 (40%), Gaps = 63/337 (18%)
Query: 31 WCSE---CHSNATCTEDEAVTTCTCQEGFTG---DGLTCVDLDECAIPGAHNCSANSSCV 84
+CSE C N+ C C+C++GF D C D+DECA G H C N+ CV
Sbjct: 400 FCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECA-EGRHYCRENTMCV 458
Query: 85 NTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
NTPGSF C+C G+ CT+ DEC +C A C N VG + CVC GY G+
Sbjct: 459 NTPGSFMCICKTGYIRIDDYSCTEHDECI-TNQHNCDENALCFNTVGGHNCVCKPGYTGN 517
Query: 145 GWHCE--CSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYA-CDT---- 197
G C+ C G C G C+ A VCA P Q E +G+ CD+
Sbjct: 518 GTTCKAFCKDG-CRNGGACIA---ANVCACP-QGFTGPSCETDIDECSDGFVQCDSRANC 572
Query: 198 -DLRGWYRFVGQGG-------ARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
+L GWY + G + E+C + C T N T + +G + C
Sbjct: 573 INLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCR-CP 631
Query: 250 HWSGHC---CLWDASVQ--------------VKACAGGYYVYNLTAPPECHLAYCTDPSS 292
H +C C+ D V+ V +C G+ + + C +P+
Sbjct: 632 H-GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRM------VCDCENPTV 684
Query: 293 VEGTCEECS--IDEDCKSNNGR--------WHCQCKQ 319
C EC + C NG W C+Q
Sbjct: 685 DLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQ 721
>gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens]
Length = 1318
Score = 107 bits (267), Expect = 3e-23
Identities = 89/312 (28%), Positives = 145/312 (46%), Gaps = 17/312 (5%)
Query: 332 RLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGT 391
R+ C + V++ K L+ + +YLS C+ + V+ A CGT
Sbjct: 990 RVLCEIEKVVVAIQKRFLQQESIPESSLYLSHPSCNVSHSNGTH----VLLEAGWSECGT 1045
Query: 392 VLTRNETHATYSNTLY--LADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIR 449
++ N T+ TL L+ E II L I C++ D+ S L+ V +
Sbjct: 1046 LMQSNMTNTVVRTTLRNDLSQEGIIHHLKILSPIYCAFQNDLLTSSGFTLEWGVYTIIED 1105
Query: 450 VGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYAT 509
+ G G F M LF S Q SV+ S + + VG +L +++T C+AT
Sbjct: 1106 LHGAGNFVTEMQLFIGDSPIP--QNYSVSASDDVRIEVGLYRQKSNLK---VVLTECWAT 1160
Query: 510 PSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVY 569
PSSNA DP+ + I + CP T V+ENG S++ +F +++F F N +VYLHC++
Sbjct: 1161 PSSNARDPITFSFINNSCPVPNTYT-NVIENGNSNKAQFKLRIFSFI-NDSIVYLHCKLR 1218
Query: 570 LC-DTMNEKCKPTCSGTRFRSGSVIDQSRVLNLGPITRKGVQATVSRAFSSLG---LLKV 625
+C ++ CK C+ R S + ++ GP+ R + + A G L+ V
Sbjct: 1219 VCMESPGATCKINCNNFRLLQNSETSATHQMSWGPLIRSEGEPPHAEAGLGAGYVVLIVV 1278
Query: 626 WLPLLLSATLTL 637
+ +L++ T TL
Sbjct: 1279 AIFVLVAGTATL 1290
Score = 36.6 bits (83), Expect = 0.073
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 60 GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
G D DEC H+CS + C+N GS++C C
Sbjct: 502 GTRVQDWDECVDSAEHDCSPAAWCINLEGSYTCQC 536
Score = 34.3 bits (77), Expect = 0.36
Identities = 14/35 (40%), Positives = 17/35 (48%)
Query: 103 GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
G D DEC + C A C+N+ GSY C C
Sbjct: 502 GTRVQDWDECVDSAEHDCSPAAWCINLEGSYTCQC 536
Score = 33.9 bits (76), Expect = 0.47
Identities = 14/30 (46%), Positives = 17/30 (56%)
Query: 108 DVDECAEPGLSHCHALATCVNVVGSYLCVC 137
DV+EC L+ C C N+ GSY CVC
Sbjct: 264 DVNECFYEELNACSGRELCANLEGSYWCVC 293
Score = 31.6 bits (70), Expect = 2.3
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
D++EC + CS C N GS+ CVC
Sbjct: 264 DVNECFYEELNACSGRELCANLEGSYWCVC 293
Score = 30.8 bits (68), Expect = 4.0
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVCPEG 97
D DEC +C +SC NT GSF+C C G
Sbjct: 897 DYDECERK-EDDCVPGTSCRNTLGSFTCSCEGG 928
>gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]
Length = 1446
Score = 107 bits (267), Expect = 3e-23
Identities = 89/312 (28%), Positives = 145/312 (46%), Gaps = 17/312 (5%)
Query: 332 RLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARDGPCGT 391
R+ C + V++ K L+ + +YLS C+ + V+ A CGT
Sbjct: 1118 RVLCEIEKVVVAIQKRFLQQESIPESSLYLSHPSCNVSHSNGTH----VLLEAGWSECGT 1173
Query: 392 VLTRNETHATYSNTLY--LADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIR 449
++ N T+ TL L+ E II L I C++ D+ S L+ V +
Sbjct: 1174 LMQSNMTNTVVRTTLRNDLSQEGIIHHLKILSPIYCAFQNDLLTSSGFTLEWGVYTIIED 1233
Query: 450 VGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYAT 509
+ G G F M LF S Q SV+ S + + VG +L +++T C+AT
Sbjct: 1234 LHGAGNFVTEMQLFIGDSPIP--QNYSVSASDDVRIEVGLYRQKSNLK---VVLTECWAT 1288
Query: 510 PSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVY 569
PSSNA DP+ + I + CP T V+ENG S++ +F +++F F N +VYLHC++
Sbjct: 1289 PSSNARDPITFSFINNSCPVPNTYT-NVIENGNSNKAQFKLRIFSFI-NDSIVYLHCKLR 1346
Query: 570 LC-DTMNEKCKPTCSGTRFRSGSVIDQSRVLNLGPITRKGVQATVSRAFSSLG---LLKV 625
+C ++ CK C+ R S + ++ GP+ R + + A G L+ V
Sbjct: 1347 VCMESPGATCKINCNNFRLLQNSETSATHQMSWGPLIRSEGEPPHAEAGLGAGYVVLIVV 1406
Query: 626 WLPLLLSATLTL 637
+ +L++ T TL
Sbjct: 1407 AIFVLVAGTATL 1418
Score = 36.6 bits (83), Expect = 0.073
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 60 GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
G D DEC H+CS + C+N GS++C C
Sbjct: 502 GTRVQDWDECVDSAEHDCSPAAWCINLEGSYTCQC 536
Score = 34.3 bits (77), Expect = 0.36
Identities = 14/35 (40%), Positives = 17/35 (48%)
Query: 103 GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
G D DEC + C A C+N+ GSY C C
Sbjct: 502 GTRVQDWDECVDSAEHDCSPAAWCINLEGSYTCQC 536
Score = 33.9 bits (76), Expect = 0.47
Identities = 14/30 (46%), Positives = 17/30 (56%)
Query: 108 DVDECAEPGLSHCHALATCVNVVGSYLCVC 137
DV+EC L+ C C N+ GSY CVC
Sbjct: 264 DVNECFYEELNACSGRELCANLEGSYWCVC 293
Score = 31.6 bits (70), Expect = 2.3
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
D++EC + CS C N GS+ CVC
Sbjct: 264 DVNECFYEELNACSGRELCANLEGSYWCVC 293
Score = 30.8 bits (68), Expect = 4.0
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVCPEG 97
D DEC +C +SC NT GSF+C C G
Sbjct: 1025 DYDECERK-EDDCVPGTSCRNTLGSFTCSCEGG 1056
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 103 bits (256), Expect = 6e-22
Identities = 112/390 (28%), Positives = 142/390 (36%), Gaps = 94/390 (24%)
Query: 34 ECHSNATCTED--EAVTT--CTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTP 87
EC + C+ A+ T C+C +G T DG TC D+DECA+ G H C A C NT
Sbjct: 5110 ECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECAL-GRHTCHAGQDCDNTI 5168
Query: 88 GSFSCV--CPEGF-RLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
GS+ CV C GF R S GL C D++EC E S CH C N +GS+ C C GY+
Sbjct: 5169 GSYRCVVRCGSGFRRTSDGLSCQDINECQES--SPCH--QRCFNAIGSFHCGCEPGYQLK 5224
Query: 145 GWHC----ECSPGSCGPGLDCVPEGDALVCADPCQAHRT---------LDEYWRSTEYGE 191
G C EC C P C C D C T +DE T
Sbjct: 5225 GRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCR 5284
Query: 192 GYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHW 251
+ RG YR V G R P + N + H S+ + C
Sbjct: 5285 YNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICP-- 5342
Query: 252 SGHCCLWDASVQVKACAG---------GYYVYNLT---------APPECHLAYC------ 287
G L D K+CAG Y YNL P + + Y
Sbjct: 5343 PGQHLLGDG----KSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSY 5398
Query: 288 -------------------TDPSSVEGTCEEC-SIDE---------DCKSNNGRWHCQCK 318
T P E + + C IDE +CK+ G + C C
Sbjct: 5399 SEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICP 5458
Query: 319 QDFNIT-------DI-SLLEHRLECGANDM 340
+ +T DI LE + CG N M
Sbjct: 5459 PGYQLTHNGKTCQDIDECLEQNVHCGPNRM 5488
Score = 84.0 bits (206), Expect = 4e-16
Identities = 50/131 (38%), Positives = 64/131 (48%), Gaps = 13/131 (9%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCT--CQEGFT-GDGLTCVDLDECAIPGAHNCSANS 81
D +E R + C + C C C G T + TC+D+DEC G H C N
Sbjct: 5230 DVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECK-DGTHQCRYNQ 5287
Query: 82 SCVNTPGSFSCVCPEGFRLSPGLG--CTDVDECAEPGLSHCHALATCVNVVGSYLCVCPA 139
C NT GS+ CVCP G+R S G+G C D++EC + H C N GS+ C+CP
Sbjct: 5288 ICENTRGSYRCVCPRGYR-SQGVGRPCMDINECEQVPKPCAH---QCSNTPGSFKCICPP 5343
Query: 140 GYR--GDGWHC 148
G GDG C
Sbjct: 5344 GQHLLGDGKSC 5354
Score = 77.8 bits (190), Expect = 3e-14
Identities = 41/98 (41%), Positives = 52/98 (53%), Gaps = 9/98 (9%)
Query: 51 TCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCTDV 109
TC EG TCVD+DEC A C NT GS+ C+CP G++L+ G C D+
Sbjct: 5418 TCPEGSEASHDTCVDIDECENTDA----CQHECKNTFGSYQCICPPGYQLTHNGKTCQDI 5473
Query: 110 DECAEPGLSHCHALATCVNVVGSYLCV---CPAGYRGD 144
DEC E + HC C N+ GSY C+ CP Y+ D
Sbjct: 5474 DECLEQNV-HCGPNRMCFNMRGSYQCIDTPCPPNYQRD 5510
Score = 69.7 bits (169), Expect = 8e-12
Identities = 70/277 (25%), Positives = 97/277 (35%), Gaps = 71/277 (25%)
Query: 52 CQEGFTGD--GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSP-GLGCTD 108
C GFT D G C D DECA + CS SC N G++ C CP+G ++ G C D
Sbjct: 5092 CPSGFTLDSVGPFCADEDECA--AGNPCS--HSCHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Query: 109 VDECAEPGLSHCHALATCVNVVGSYLCV--CPAGYRGDGWHCECSPGSCGPGLDCVPEGD 166
+DECA G CHA C N +GSY CV C +G+R GL C D
Sbjct: 5148 IDECAL-GRHTCHAGQDCDNTIGSYRCVVRCGSGFR-----------RTSDGLSCQ---D 5192
Query: 167 ALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTA 226
C + H+ C + ++ G C+ V C
Sbjct: 5193 INECQESSPCHQR---------------CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ- 5236
Query: 227 APMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNL--TAPPECHL 284
N P HC K GGY +L +
Sbjct: 5237 -----NVCRPDQ---------------HC---------KNTRGGYKCIDLCPNGMTKAEN 5267
Query: 285 AYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDF 321
C D + +C ++ C++ G + C C + +
Sbjct: 5268 GTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGY 5304
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 10/81 (12%)
Query: 34 ECHSNATCTEDEAVT----TCTCQEGF--TGDGLTCVDLDECAIPGAHNCSANSSCVNTP 87
EC + C + T C C G+ T +G TC D+DEC H C N C N
Sbjct: 5435 ECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVH-CGPNRMCFNMR 5493
Query: 88 GSFSCV---CPEGFRLSPGLG 105
GS+ C+ CP ++ P G
Sbjct: 5494 GSYQCIDTPCPPNYQRDPVSG 5514
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 102 bits (255), Expect = 8e-22
Identities = 54/132 (40%), Positives = 70/132 (53%), Gaps = 7/132 (5%)
Query: 21 TAATDTSEAR-WCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSA 79
T TD +E C +A CT C+C G+ GDG+ C DLDEC+ G H CS
Sbjct: 1318 TGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECS-NGTHMCSQ 1376
Query: 80 NSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPA 139
++ C NT GS+ C+C EG+ G CTD+DEC+E L+ C C+N G Y C C
Sbjct: 1377 HADCKNTMGSYRCLCKEGY-TGDGFTCTDLDECSE-NLNLC-GNGQCLNAPGGYRCECDM 1433
Query: 140 GY--RGDGWHCE 149
G+ DG CE
Sbjct: 1434 GFVPSADGKACE 1445
Score = 100 bits (248), Expect = 5e-21
Identities = 88/340 (25%), Positives = 126/340 (37%), Gaps = 68/340 (20%)
Query: 34 ECHSNATCTEDEAVTT-----CTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPG 88
EC C + + T C C G+ G CVD DEC++ N N +C N G
Sbjct: 2130 ECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVG---NPCGNGTCKNVIG 2186
Query: 89 SFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY--RGDGW 146
F C C EGF P + C D++ECA+ L CVN GSY C CP GY R D
Sbjct: 2187 GFECTCEEGFEPGPMMTCEDINECAQNPLL---CAFRCVNTYGSYECKCPVGYVLREDRR 2243
Query: 147 HC----ECSPGS--------------------CGPGLDCVPEGDALVCADPCQAHRTLDE 182
C EC G CGPG P+G+ V + CQ + E
Sbjct: 2244 MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE 2303
Query: 183 YWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLR--CNTAAPMWLNGTHPSSDE 240
R Y C+ + G + + C+ C T + S+
Sbjct: 2304 NGRCLNTRGSYTCECN-------DGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRN 2356
Query: 241 GIVSRKACAH----WSGHC--CLWDASVQVKACA--GGYYVYNLTAPPECHLAYCTDPSS 292
+ + C W HC C + +V K G ++ N EC +
Sbjct: 2357 PVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKV-------- 2408
Query: 293 VEGTCEECSIDEDCKSNNGRWHCQCKQDF--NITDISLLE 330
+ C + +C ++ G +HC CK + +IT S ++
Sbjct: 2409 IHDVCR----NGECVNDRGSYHCICKTGYTPDITGTSCVD 2444
Score = 98.2 bits (243), Expect = 2e-20
Identities = 98/375 (26%), Positives = 136/375 (36%), Gaps = 74/375 (19%)
Query: 24 TDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGL---TCVDLDECAIPGAHNCSAN 80
TD E R + C C C EG+ + C+D+DEC
Sbjct: 1069 TDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPL--LCRG 1126
Query: 81 SSCVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPA 139
C NT GS+ C CP G +LSP + C D++EC +H CVN++G Y C C
Sbjct: 1127 GVCHNTEGSYRCECPPGHQLSPNISACIDINECELS--AHLCPNGRCVNLIGKYQCACNP 1184
Query: 140 GYRG--DGWHC----ECS-----------------PGSCGPGLDCVPEGDALVCADPCQA 176
GY D C ECS SC PG +P D C D
Sbjct: 1185 GYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMP--DQRSCTD---- 1238
Query: 177 HRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAE---TCVPVLRCNTAAPMWLNG 233
+DE + +G C T++ G YR + G +E TCV V C+ + L+G
Sbjct: 1239 ---IDECEDNPNICDGGQC-TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSG 1294
Query: 234 THPSS--------DEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLA 285
T ++ D G +K +G + + + C N +C +
Sbjct: 1295 TCENTKGSFICHCDMGYSGKKG---KTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCS 1351
Query: 286 --------YCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQ-----DFNITDISLLEHR 332
CTD CS DCK+ G + C CK+ F TD+
Sbjct: 1352 PGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLD----- 1406
Query: 333 LECGANDMKVSLGKC 347
EC N G+C
Sbjct: 1407 -ECSENLNLCGNGQC 1420
Score = 97.1 bits (240), Expect = 5e-20
Identities = 56/147 (38%), Positives = 72/147 (48%), Gaps = 14/147 (9%)
Query: 35 CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
C +A C C C+EG+TGDG TC DLDEC+ N N C+N PG + C C
Sbjct: 1374 CSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECS--ENLNLCGNGQCLNAPGGYRCEC 1431
Query: 95 PEGFRLS-PGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD--GWHC--- 148
GF S G C D+DEC+ P + TC N+ G + C C GY D G +C
Sbjct: 1432 DMGFVPSADGKACEDIDECSLPNIC---VFGTCHNLPGLFRCECEIGYELDRSGGNCTDV 1488
Query: 149 -EC-SPGSCGPGLDCVPEGDALVCADP 173
EC P +C G +CV + +C P
Sbjct: 1489 NECLDPTTCISG-NCVNTPGSYICDCP 1514
Score = 95.5 bits (236), Expect = 1e-19
Identities = 99/335 (29%), Positives = 131/335 (39%), Gaps = 53/335 (15%)
Query: 38 NATCTEDEAVTTCTCQEGFT-GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPE 96
N TC C C GF C+D+DECA G N N C+NT GSF C C E
Sbjct: 1902 NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECA-SGNGNLCRNGQCINTVGSFQCQCNE 1960
Query: 97 GFRLSP-GLGCTDVDECA-EPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCE----- 149
G+ ++P G C D++EC EP C A TC N+ GSY C+CP GY CE
Sbjct: 1961 GYEVAPDGRTCVDINECLLEP--RKC-APGTCQNLDGSYRCICPPGYSLQNEKCEDIDEC 2017
Query: 150 ------CSPGSCG---PGLDCV-PEGDALVCAD-PCQAHRTLDEYWRSTEYGEGYACDTD 198
C+ G+C C+ PEG +L + CQ R Y + EG C +
Sbjct: 2018 VEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKF----EGGKCSSP 2073
Query: 199 LRGWY-------RFVGQGGARMAETC--VPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
+ G+G E C P P + +G D+ V C
Sbjct: 2074 KSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICP-YGSGIIVGPDDSAVDMDECK 2132
Query: 250 H----WSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDED 305
G C D S + + C GY + A EC TD SV C +
Sbjct: 2133 EPDVCKHGQCINTDGSYRCE-CPFGY----ILAGNEC---VDTDECSVGNPCG----NGT 2180
Query: 306 CKSNNGRWHCQCKQDFNITDISLLEHRLECGANDM 340
CK+ G + C C++ F + E EC N +
Sbjct: 2181 CKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPL 2215
Score = 87.0 bits (214), Expect = 5e-17
Identities = 60/180 (33%), Positives = 78/180 (43%), Gaps = 18/180 (10%)
Query: 18 FITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAH 75
F+T A D E + + N C D C C+ G+T D G +CVDL+EC
Sbjct: 2396 FMTNGA-DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC---NQA 2451
Query: 76 NCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYL 134
N C NT GS+ C CP+G+ L G C D+DECA +C L CVN +G +
Sbjct: 2452 PKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATK-QHNCQFL--CVNTIGGFT 2508
Query: 135 CVCPAGYRG------DGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTE 188
C CP G+ D C CG C + C CQ +LD+ S E
Sbjct: 2509 CKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTC--ECQRGFSLDQTGSSCE 2566
Score = 86.3 bits (212), Expect = 8e-17
Identities = 93/341 (27%), Positives = 120/341 (35%), Gaps = 74/341 (21%)
Query: 3 QPSLTWMLMVVVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGF--TGDG 60
Q S T S T D E +N C + C C GF T DG
Sbjct: 508 QGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDG 567
Query: 61 LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSH 119
C D+DEC+I N N C+N GSF C+C GF+L S G C D++EC PG+
Sbjct: 568 KNCEDMDECSI---RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGIC- 623
Query: 120 CHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRT 179
CVN GSY CEC PG GL D VC
Sbjct: 624 --MNGRCVNTDGSY-------------RCECFPG-LAVGL------DGRVC--------- 652
Query: 180 LDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAET-------CVPVLRCNTAAPMWLN 232
+D + RST YG GY ++ + V + A T C P N+A L
Sbjct: 653 VDTHMRSTCYG-GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALC 711
Query: 233 GTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSS 292
+ P CA + C G NL +C C
Sbjct: 712 SSGPGMTSAGSDINECA------------LDPDICPNG-ICENLRGTYKC---ICNSGYE 755
Query: 293 VEGTCEEC-SIDE-----------DCKSNNGRWHCQCKQDF 321
V+ T + C I+E C++ G + C C + F
Sbjct: 756 VDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGF 796
Score = 84.3 bits (207), Expect = 3e-16
Identities = 55/149 (36%), Positives = 68/149 (45%), Gaps = 15/149 (10%)
Query: 20 TTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGF-TGDGLT-CVDLDECAIPGAHNC 77
T D +E + S+ C + C C GF T D T C+D++EC +
Sbjct: 1844 TGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECE----RDA 1899
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
N +C NT GSF+C C GF LS C DVDECA + C C+N VGS+ C C
Sbjct: 1900 CGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQC 1958
Query: 138 PAGYR--GDGWHC----EC--SPGSCGPG 158
GY DG C EC P C PG
Sbjct: 1959 NEGYEVAPDGRTCVDINECLLEPRKCAPG 1987
Score = 84.0 bits (206), Expect = 4e-16
Identities = 89/334 (26%), Positives = 116/334 (34%), Gaps = 77/334 (23%)
Query: 41 CTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGF 98
CT E C+CQ GF D +C D+DEC N C N PG + C+C +GF
Sbjct: 1212 CTNSEGSYECSCQPGFALMPDQRSCTDIDECE--DNPNICDGGQCTNIPGEYRCLCYDGF 1269
Query: 99 RLSPGLG-CTDVDEC-AEPGLSHCHALATCVNVVGSYLCVCPAGYRG------------- 143
S + C DV+EC P + TC N GS++C C GY G
Sbjct: 1270 MASEDMKTCVDVNECDLNPNIC---LSGTCENTKGSFICHCDMGYSGKKGKTGCTDINEC 1326
Query: 144 -----------------DGWHCECSPGSCGPGLDCVP----EGDALVCADPCQAHRTLDE 182
+ C CSPG G G+ C +C+ T+
Sbjct: 1327 EIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGS 1386
Query: 183 Y---WRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSD 239
Y + G+G+ C TDL + G RC G PS+D
Sbjct: 1387 YRCLCKEGYTGDGFTC-TDLDECSENLNLCGNGQCLNAPGGYRCECDM-----GFVPSAD 1440
Query: 240 EGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTA--PPECHLAYCTDPSSVEGTC 297
KAC C L C G +NL EC + Y D S G C
Sbjct: 1441 -----GKACED-IDECSL------PNICVFG-TCHNLPGLFRCECEIGYELDRSG--GNC 1485
Query: 298 ---EEC-----SIDEDCKSNNGRWHCQCKQDFNI 323
EC I +C + G + C C DF +
Sbjct: 1486 TDVNECLDPTTCISGNCVNTPGSYICDCPPDFEL 1519
Score = 82.0 bits (201), Expect = 2e-15
Identities = 51/140 (36%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 49 TCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRL-SPGLGCT 107
TC C GFT +C+D +EC + C + C NTPGSF+C C GF L G C
Sbjct: 2508 TCKCPPGFTQHHTSCIDNNECT-SDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE 2566
Query: 108 DVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY-RGDGWHCECSPGSCGPGLDCVPEGD 166
DVDEC G C C N++G Y C CP GY + W+ CV E +
Sbjct: 2567 DVDEC--EGNHRCQ--HGCQNIIGGYRCSCPQGYLQHYQWN------------QCVDENE 2610
Query: 167 AL---VCADPCQAHRTLDEY 183
L +C H TL Y
Sbjct: 2611 CLSAHICGG-ASCHNTLGSY 2629
Score = 77.8 bits (190), Expect = 3e-14
Identities = 87/375 (23%), Positives = 133/375 (35%), Gaps = 46/375 (12%)
Query: 31 WCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCV--DLDECA-IPGAHNCSANSSCVNTP 87
W + C E C EGF + +T + D+DEC +PG C+NT
Sbjct: 1570 WGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL---CQGGKCINTF 1626
Query: 88 GSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGW 146
GSF C CP G+ L+ C DV+EC PG+ TC N VG+Y C+CP Y
Sbjct: 1627 GSFQCRCPTGYYLNEDTRVCDDVNECETPGIC---GPGTCYNTVGNYTCICPPDYM---- 1679
Query: 147 HCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDL-RGWYRF 205
G +C+ +L + ++T D + C ++ R W +
Sbjct: 1680 -------QVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKP 1732
Query: 206 VGQGGARMAETCVPVLRCNTAAPMWL----NGTHPSSDEGIVSRKACAHWSGHCCLWDAS 261
Q + T C + P ++ G DE C +G C S
Sbjct: 1733 CEQ--CPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCE--NGVCINMVGS 1788
Query: 262 VQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDF 321
+ + G +Y L C D + C + +C + G + C CK +
Sbjct: 1789 FRCECPVGFFY--------NDKLLVCEDIDECQNG-PVCQRNAECINTAGSYRCDCKPGY 1839
Query: 322 NITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVV 381
T R EC S G+C + ++G + +GF D++ +
Sbjct: 1840 RFTSTGQCNDRNECQEIPNICSHGQC-IDTVGSFYCLCH------TGFKTNDDQTMCLDI 1892
Query: 382 TPARDGPCGTVLTRN 396
CG RN
Sbjct: 1893 NECERDACGNGTCRN 1907
Score = 77.8 bits (190), Expect = 3e-14
Identities = 45/126 (35%), Positives = 60/126 (47%), Gaps = 11/126 (8%)
Query: 35 CHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSC 92
C S C TC CQ GF+ D G +C D+DEC G H C C N G + C
Sbjct: 2535 CGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE--GNHRCQ--HGCQNIIGGYRC 2590
Query: 93 VCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECS 151
CP+G+ C D +EC +H A+C N +GSY C+CPAG++ + + C
Sbjct: 2591 SCPQGYLQHYQWNQCVDENECLS---AHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647
Query: 152 P-GSCG 156
CG
Sbjct: 2648 DINECG 2653
Score = 76.6 bits (187), Expect = 6e-14
Identities = 44/122 (36%), Positives = 57/122 (46%), Gaps = 9/122 (7%)
Query: 19 ITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHN 76
+T+A +D +E + N C C C G+ D G CVD++EC +
Sbjct: 717 MTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSL-- 774
Query: 77 CSANSSCVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
N C NTPGSF C CP+GF P L C D+DEC S C C N GS++C
Sbjct: 775 LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECES---SPC-INGVCKNSPGSFIC 830
Query: 136 VC 137
C
Sbjct: 831 EC 832
Score = 76.6 bits (187), Expect = 6e-14
Identities = 85/363 (23%), Positives = 124/363 (34%), Gaps = 88/363 (24%)
Query: 20 TTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDG--LTCVDLDECAIPGAHNC 77
T D E R N C C C GF + L C D+DEC C
Sbjct: 1761 TGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ--NGPVC 1818
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
N+ C+NT GS+ C C G+R + C D +EC E + + + C++ VGS+ C+C
Sbjct: 1819 QRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLC 1876
Query: 138 PAGYR--GDGWHC----ECSPGSCGPGL----------------------DCV-----PE 164
G++ D C EC +CG G DC+
Sbjct: 1877 HTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECAS 1936
Query: 165 GDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCN 224
G+ +C + Q T+ + + EGY D R TCV + C
Sbjct: 1937 GNGNLCRNG-QCINTVGSF--QCQCNEGYEVAPDGR---------------TCVDINEC- 1977
Query: 225 TAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHL 284
++ + CA G C D S + C GY + N
Sbjct: 1978 -----------------LLEPRKCA--PGTCQNLDGSYRC-ICPPGYSLQN--------- 2008
Query: 285 AYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSL 344
C D E C++ C + G + C C + F+++ L K
Sbjct: 2009 EKCEDIDECVEEPEICALG-TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEG 2067
Query: 345 GKC 347
GKC
Sbjct: 2068 GKC 2070
Score = 75.9 bits (185), Expect = 1e-13
Identities = 105/422 (24%), Positives = 163/422 (38%), Gaps = 80/422 (18%)
Query: 38 NATCTEDEAVTTCTCQEGFTGDGL-TCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPE 96
N C C C +GF D C+D+DEC N A C+N GS++C C
Sbjct: 462 NGRCIPTPGSCRCECNKGFQLDLRGECIDVDECE----KNPCAGGECINNQGSYTCQCRA 517
Query: 97 GFRLS-PGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC----E 149
G++ + C D+DEC + G C+ C+N GS+ CVC AG+ DG +C E
Sbjct: 518 GYQSTLTRTECRDIDECLQNG-RICNN-GRCINTDGSFHCVCNAGFHVTRDGKNCEDMDE 575
Query: 150 CS-PGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTD---LRGWYRF 205
CS C G+ C+ E + C C+ L R + + C+T + G R
Sbjct: 576 CSIRNMCLNGM-CINEDGSFKCI--CKPGFQLASDGRYCK--DINECETPGICMNG--RC 628
Query: 206 VGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKAC------AHWSGHCCLWD 259
V G+ E C P L + ++ S+ G R C A CC
Sbjct: 629 VNTDGSYRCE-CFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECC--- 684
Query: 260 ASVQVKACAGGYYVYNLTAPPEC-------HLAYCTD---PSSVEGTCEECSIDED---- 305
CA Y + P C + A C+ +S EC++D D
Sbjct: 685 -------CASTEYAFGEPCQP-CPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPN 736
Query: 306 --CKSNNGRWHCQCKQDF-------NITDISLLEHRLECGANDMKVSLGKCQLKSLGF-- 354
C++ G + C C + N DI+ EC N + G+C+ F
Sbjct: 737 GICENLRGTYKCICNSGYEVDSTGKNCVDIN------ECVLNSLLCDNGQCRNTPGSFVC 790
Query: 355 --DKVFMYLSDSR-CSGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADE 411
K F+Y D + C ++ ++ ++ V ++ P G+ + + +T T + E
Sbjct: 791 TCPKGFIYKPDLKTCEDIDECESSPCINGV--CKNSP-GSFICECSSESTLDPTKTICIE 847
Query: 412 II 413
I
Sbjct: 848 TI 849
Score = 74.7 bits (182), Expect = 2e-13
Identities = 47/112 (41%), Positives = 59/112 (52%), Gaps = 14/112 (12%)
Query: 52 CQEGFTGDGLT--CVDLDEC-AIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSP-GLGCT 107
C+ GF + T C D+DEC AIPG +C+NT GSF C CP G +L+ C
Sbjct: 231 CRRGFIPNIRTGACQDVDECQAIPGL---CQGGNCINTVGSFECKCPAGHKLNEVSQKCE 287
Query: 108 DVDECAE-PGLSHCHALATCVNVVGSYLCVCPAGY--RGDGWHC-ECSPGSC 155
D+DEC+ PG+ C C N V SY C CP G+ DG C + PG C
Sbjct: 288 DIDECSTIPGI--CEG-GECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYC 336
Score = 63.9 bits (154), Expect = 4e-10
Identities = 43/131 (32%), Positives = 57/131 (43%), Gaps = 15/131 (11%)
Query: 50 CTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCTD 108
C GF +G D+DEC + H+ N CVN GS+ C+C G+ G C D
Sbjct: 2390 CPHGRGFMTNG---ADIDECKV--IHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVD 2444
Query: 109 VDECAEPGLSHCHALATCVNVVGSYLCVCPAGY--RGDGWHC----ECSPGSCGPGLDCV 162
++EC + C+ + C N GSY C CP GY + DG C EC+ CV
Sbjct: 2445 LNECNQ-APKPCNFI--CKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCV 2501
Query: 163 PEGDALVCADP 173
C P
Sbjct: 2502 NTIGGFTCKCP 2512
Score = 62.0 bits (149), Expect = 2e-09
Identities = 74/301 (24%), Positives = 108/301 (35%), Gaps = 35/301 (11%)
Query: 40 TCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFR 99
TC + C C G++ C D+DEC + C A +C NT GSF C+CPEGF
Sbjct: 1988 TCQNLDGSYRCICPPGYSLQNEKCEDIDEC-VEEPEIC-ALGTCSNTEGSFKCLCPEGFS 2045
Query: 100 LSPGLGCTDVDECAEPGLSHCHAL---ATCVNVV----GSYLCVCPAGYRGDGW--HCEC 150
LS + C + +S+C+A C + C C +G+GW CE
Sbjct: 2046 LS-----SSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCC--ALKGEGWGDPCEL 2098
Query: 151 SPGSCGPGL-DCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQG 209
P P G ++ P + +DE G +TD G YR
Sbjct: 2099 CPTEPDEAFRQICPYGSGII-VGPDDSAVDMDECKEPDVCKHGQCINTD--GSYRCECPF 2155
Query: 210 GARMA-ETCVPVLRCNTAAPMW-------LNGTHPSSDEGIVSRKACAHWSGHCCLWDAS 261
G +A CV C+ P + G + +EG + C +
Sbjct: 2156 GYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPL 2215
Query: 262 VQVKACAGGYYVYNLTAPPECHL----AYCTDPSSVEGTCEECSIDE-DCKSNNGRWHCQ 316
+ C Y Y P L C D E +C+ + +CK+ G + C
Sbjct: 2216 LCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCI 2275
Query: 317 C 317
C
Sbjct: 2276 C 2276
Score = 53.5 bits (127), Expect = 6e-07
Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 6/72 (8%)
Query: 40 TCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEG 97
TC + C C+ G+ D G C D++EC P + +CVNTPGS+ C CP
Sbjct: 1460 TCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDP---TTCISGNCVNTPGSYICDCPPD 1516
Query: 98 FRLSP-GLGCTD 108
F L+P +GC D
Sbjct: 1517 FELNPTRVGCVD 1528
Score = 50.8 bits (120), Expect = 4e-06
Identities = 50/174 (28%), Positives = 64/174 (36%), Gaps = 37/174 (21%)
Query: 38 NATCTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCP 95
N C CTC +GF D TC D+DEC + N C N+PGSF C C
Sbjct: 778 NGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECE----SSPCINGVCKNSPGSFICECS 833
Query: 96 EGFRLSPGLGC-----------TDVDECAEPGLSHCHALATCVNVVGS------YLC--- 135
L P T +D E ++ + C + +G+ LC
Sbjct: 834 SESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVD 893
Query: 136 -VCPAGYR-------GDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLD 181
+C GY D CE PG C GL CV + C C + TLD
Sbjct: 894 PICGKGYSRIKGTQCEDIDECEVFPGVCKNGL-CVNTRGSFKC--QCPSGMTLD 944
Score = 50.4 bits (119), Expect = 5e-06
Identities = 42/136 (30%), Positives = 53/136 (38%), Gaps = 22/136 (16%)
Query: 33 SECHSNATCTEDEAVTTCT----CQEGFTG-DGLTCVDLDECAI-PGAHNCSANSSCVNT 86
S+C S+ T C C +G++ G C D+DEC + PG N CVNT
Sbjct: 873 SQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGV---CKNGLCVNT 929
Query: 87 PGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDG 145
GSF C CP G L + G C D+ L TC C P R
Sbjct: 930 RGSFKCQCPSGMTLDATGRICLDI------------RLETCFLRYEDEECTLPIAGRHRM 977
Query: 146 WHCECSPGSCGPGLDC 161
C CS G+ +C
Sbjct: 978 DACCCSVGAAWGTEEC 993
Score = 48.5 bits (114), Expect = 2e-05
Identities = 86/393 (21%), Positives = 122/393 (31%), Gaps = 110/393 (27%)
Query: 21 TAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDL-----------D 67
T D E N C C C G T D G C+D+ +
Sbjct: 906 TQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDE 965
Query: 68 ECAIP--GAHNCSANSSCV---------------NTPGSFSCVCPEGFRLSPGLGCT--- 107
EC +P G H A V NTP + +CP G PG
Sbjct: 966 ECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTP-EYEELCPRG----PGFATKEIT 1020
Query: 108 -------DVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGW--------HCECSP 152
D++EC H C N +GS+ C C +G+ D C SP
Sbjct: 1021 NGKPFFKDINECKMIPSLCTHG--KCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISP 1078
Query: 153 GSCGPGLDCVPEGDALVCADP--------CQAHRTLDEYWRSTEYGEGYACDTDLRGWYR 204
CG G GD D + +DE R G C + G YR
Sbjct: 1079 DLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCH-NTEGSYR 1137
Query: 205 FVGQGGARMA---ETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCCLWDAS 261
G +++ C+ + C +A + NG + ++ + C
Sbjct: 1138 CECPPGHQLSPNISACIDINECELSAHLCPNGRCVN----LIGKYQC------------- 1180
Query: 262 VQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDF 321
AC GY+ + P + S + G CE C ++ G + C C+ F
Sbjct: 1181 ----ACNPGYH----STPDRLFCVDIDECSIMNGGCETF-----CTNSEGSYECSCQPGF 1227
Query: 322 -------NITDISLLEHRLECGANDMKVSLGKC 347
+ TDI EC N G+C
Sbjct: 1228 ALMPDQRSCTDID------ECEDNPNICDGGQC 1254
>gi|42476320 sushi domain containing 1 [Homo sapiens]
Length = 747
Score = 102 bits (254), Expect = 1e-21
Identities = 51/120 (42%), Positives = 63/120 (52%), Gaps = 12/120 (10%)
Query: 32 CSECHSNATCTEDEAVTTCTCQEGFTGDGLT-CVDLDECAIPGAHNCSANSSCVNTPGSF 90
C+ CH +ATC + E C C GF G+G T CVD +EC C ++SC NTPG F
Sbjct: 39 CATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGF 98
Query: 91 SCVCPEGFRL---------SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY 141
C+C EG+R + G CTD+DEC GL C CVN GS+ C C GY
Sbjct: 99 YCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL--CRHGGRCVNTHGSFECYCMDGY 156
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/120 (29%), Positives = 45/120 (37%), Gaps = 20/120 (16%)
Query: 66 LDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALAT 125
LD CA C +++C G C+C GF + C D +EC C +
Sbjct: 36 LDVCA-----TCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTS 90
Query: 126 CVNVVGSYLCVCPAGYR----------GDGWHC----ECS-PGSCGPGLDCVPEGDALVC 170
C N G + C+C GYR DG C EC G C G CV + C
Sbjct: 91 CHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGLCRHGGRCVNTHGSFEC 150
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 101 bits (252), Expect = 2e-21
Identities = 91/318 (28%), Positives = 119/318 (37%), Gaps = 59/318 (18%)
Query: 21 TAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDEC-AIPGAHNC 77
T D E R + C C C GF C+D+DEC +P +
Sbjct: 516 TRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL 575
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAE-PGLSHCHALATCVNVVGSYLC 135
C NTPGSF CVCP G++ +P G C DVDEC + PGL C N+ GS+ C
Sbjct: 576 GR---CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC---GRGACKNLPGSFRC 629
Query: 136 VCPAGYRG-----DGWHCECSPGSCGPGLDCVPEGDALVCA-----------DPCQAHRT 179
VCPAG+RG D C P CGPG C + CA PCQ
Sbjct: 630 VCPAGFRGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGAPCQ---D 685
Query: 180 LDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSD 239
+DE RS C+ + G ++ V C + NTA G+
Sbjct: 686 VDECARSPPPCTYGRCE-NTEGSFQCV----------CPMGFQPNTA------GSECEDV 728
Query: 240 EGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEE 299
+ + AC C S Q + C G+++ H CTD
Sbjct: 729 DECENHLACP--GQECVNSPGSFQCRTCPSGHHL---------HRGRCTDVDECSSGAPP 777
Query: 300 CSIDEDCKSNNGRWHCQC 317
C C + G + C C
Sbjct: 778 CGPHGHCTNTEGSFRCSC 795
Score = 90.9 bits (224), Expect = 3e-18
Identities = 73/235 (31%), Positives = 95/235 (40%), Gaps = 49/235 (20%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSANSS 82
D +E C + C + CTC G+ G +C+D+DEC+ + +
Sbjct: 811 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS---EEDLCQSGI 867
Query: 83 CVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCHALATCVNVVGSYLCV--CPA 139
C NT GSF C+CP G R P L C DVDEC E G + C + C N GSY CV C
Sbjct: 868 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS-QRCENSPGSYRCVRDCDP 926
Query: 140 GYRG--------------------DGWHCECSPGS------CGPGLDCVPEGDALVCADP 173
GY CE +PGS C PG P G C D
Sbjct: 927 GYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG---CQD- 982
Query: 174 CQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFV---GQGGARMAETCVPVLRCNT 225
+DE R+ + +A +L G ++ + G GAR CV V C T
Sbjct: 983 ------VDE-CRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1030
Score = 80.5 bits (197), Expect = 4e-15
Identities = 102/393 (25%), Positives = 132/393 (33%), Gaps = 90/393 (22%)
Query: 24 TDTSEARWCSECHSNATCTEDEAVTT-----C-TCQEGFTGDGLTCVDLDECAIPGAHNC 77
T SE EC ++ C E V + C TC G C D+DEC+ GA C
Sbjct: 720 TAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECS-SGAPPC 778
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSPGL--GCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
+ C NT GSF C C G+R G C DV+EC E C C+N GS+ C
Sbjct: 779 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEG--DFCFPHGECLNTDGSFAC 836
Query: 136 VCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYAC 195
C GYR PG P G + + D C G
Sbjct: 837 TCAPGYR---------PG---------PRGASCLDVDECSEEDLCQ---------SGICT 869
Query: 196 DTDLRGWYRFVGQGGARMA---ETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWS 252
+TD G + + G R +C+ V C P + G S
Sbjct: 870 NTD--GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG----------S 917
Query: 253 GHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGR 312
C V+ C GY+ A PE C D + E + C++ G
Sbjct: 918 YRC--------VRDCDPGYH-----AGPE---GTCDDVDECQEYGPEICGAQRCENTPGS 961
Query: 313 WHC--QCKQDFNIT------DISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDS 364
+ C C + T D+ +R CGA+ + CQ F L D
Sbjct: 962 YRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAV------CQ----NLPGSFQCLCDQ 1011
Query: 365 RCSGFNDRDNRDWVSV-VTPARDGPCGTVLTRN 396
G RD R V V G CG L N
Sbjct: 1012 GYEG--ARDGRHCVDVNECETLQGVCGAALCEN 1042
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/92 (41%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 49 TCTCQEGFTGD-GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFR-LSPGLGC 106
T C G+ G C D+DEC C A++ C N PGSF C+C +G+ G C
Sbjct: 965 TPACDPGYQPTPGGGCQDVDECR--NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC 1022
Query: 107 TDVDECAEPGLSHCHALATCVNVVGSYLCVCP 138
DV+EC L A C NV GS+LCVCP
Sbjct: 1023 VDVNECET--LQGVCGAALCENVEGSFLCVCP 1052
Score = 65.9 bits (159), Expect = 1e-10
Identities = 78/303 (25%), Positives = 103/303 (33%), Gaps = 77/303 (25%)
Query: 83 CVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY 141
C++ P ++C C GFRLSP G C DVDEC + A C N GS+ CVC G+
Sbjct: 494 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRR--VPPPCAPGRCENSPGSFRCVCGPGF 551
Query: 142 RG--------------------DGWHCECSPGS----CGPGLDCVPEGDALVCADPCQAH 177
R D CE +PGS C G P G + D C
Sbjct: 552 RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 611
Query: 178 RTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPS 237
L G G AC +L G +R V G R + V C P G
Sbjct: 612 PGL--------CGRG-AC-KNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG---- 657
Query: 238 SDEGIVSRKACAHWSG--HCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEG 295
C + +G HC AC G+ AP C D
Sbjct: 658 ---------RCDNTAGSFHC----------ACPAGFRSRGPGAP-------CQDVDECAR 691
Query: 296 TCEECSIDEDCKSNNGRWHCQCKQDF-------NITDISLLEHRLECGANDMKVSLGKCQ 348
+ C+ C++ G + C C F D+ E+ L C + S G Q
Sbjct: 692 SPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQ 750
Query: 349 LKS 351
++
Sbjct: 751 CRT 753
Score = 57.0 bits (136), Expect = 5e-08
Identities = 59/185 (31%), Positives = 71/185 (38%), Gaps = 25/185 (13%)
Query: 31 WCSECHSNATCTEDEAVTTCTCQEGF-----TGDGLTCVDLDECAIPGAHNCSANSSCVN 85
W S C + A C G +GD D+DEC + C + CVN
Sbjct: 1147 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVN 1205
Query: 86 TPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
T +SC C G+ + L C D DECA+ + C CVN VGSY C C D
Sbjct: 1206 TAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA-CEG-GRCVNTVGSYHCTCEPPLVLD 1263
Query: 145 GWHCECSPGSCGPGLD-----CVPE-GDALVCADPCQAHRTLDEYWRSTE----YGEGYA 194
G C LD C E G LVC +H LD TE YGE +
Sbjct: 1264 GSQRRCVSNE-SQSLDDNLGVCWQEVGADLVC-----SHPRLDRQATYTECCCLYGEAWG 1317
Query: 195 CDTDL 199
D L
Sbjct: 1318 MDCAL 1322
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 64 VDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCTDVDECAE-PGLSHCH 121
++ +EC I C+ N CV P F+C C +G+RL + C D++EC E S
Sbjct: 1465 LEAEECGI--LDGCT-NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC 1521
Query: 122 ALATCVNVVGSYLCVCPAGYRGDGWHCECSP 152
A C+N GS+ C+C G+ C+P
Sbjct: 1522 VNARCLNTDGSFRCICRPGFAPTHQPHHCAP 1552
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/84 (38%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 73 GAHNCS------ANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATC 126
G H+C NS V+ P CP GF G C DVDECA G C C
Sbjct: 253 GVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNG-SCEDVDECATGG--RCQH-GEC 305
Query: 127 VNVVGSYLCVCPAGYRGDGWHCEC 150
N G Y CVCP G+ D C
Sbjct: 306 ANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 32 CSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFS 91
C C +E + C GF +C D+DECA G C + C NT G ++
Sbjct: 257 CQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGG--RCQ-HGECANTRGGYT 313
Query: 92 CVCPEGFRL 100
CVCP+GF L
Sbjct: 314 CVCPDGFLL 322
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 37 SNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDEC-AIPGAHNCSANSSCVNTPGSFSCV 93
+N C TC C +G+ D + CVD++EC A N+ C+NT GSF C+
Sbjct: 1477 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
Query: 94 CPEGF 98
C GF
Sbjct: 1537 CRPGF 1541
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 101 bits (252), Expect = 2e-21
Identities = 91/318 (28%), Positives = 119/318 (37%), Gaps = 59/318 (18%)
Query: 21 TAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDEC-AIPGAHNC 77
T D E R + C C C GF C+D+DEC +P +
Sbjct: 546 TRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL 605
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAE-PGLSHCHALATCVNVVGSYLC 135
C NTPGSF CVCP G++ +P G C DVDEC + PGL C N+ GS+ C
Sbjct: 606 GR---CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC---GRGACKNLPGSFRC 659
Query: 136 VCPAGYRG-----DGWHCECSPGSCGPGLDCVPEGDALVCA-----------DPCQAHRT 179
VCPAG+RG D C P CGPG C + CA PCQ
Sbjct: 660 VCPAGFRGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGAPCQ---D 715
Query: 180 LDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSD 239
+DE RS C+ + G ++ V C + NTA G+
Sbjct: 716 VDECARSPPPCTYGRCE-NTEGSFQCV----------CPMGFQPNTA------GSECEDV 758
Query: 240 EGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEE 299
+ + AC C S Q + C G+++ H CTD
Sbjct: 759 DECENHLACP--GQECVNSPGSFQCRTCPSGHHL---------HRGRCTDVDECSSGAPP 807
Query: 300 CSIDEDCKSNNGRWHCQC 317
C C + G + C C
Sbjct: 808 CGPHGHCTNTEGSFRCSC 825
Score = 90.9 bits (224), Expect = 3e-18
Identities = 73/235 (31%), Positives = 95/235 (40%), Gaps = 49/235 (20%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSANSS 82
D +E C + C + CTC G+ G +C+D+DEC+ + +
Sbjct: 841 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS---EEDLCQSGI 897
Query: 83 CVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCHALATCVNVVGSYLCV--CPA 139
C NT GSF C+CP G R P L C DVDEC E G + C + C N GSY CV C
Sbjct: 898 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS-QRCENSPGSYRCVRDCDP 956
Query: 140 GYRG--------------------DGWHCECSPGS------CGPGLDCVPEGDALVCADP 173
GY CE +PGS C PG P G C D
Sbjct: 957 GYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG---CQD- 1012
Query: 174 CQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFV---GQGGARMAETCVPVLRCNT 225
+DE R+ + +A +L G ++ + G GAR CV V C T
Sbjct: 1013 ------VDE-CRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1060
Score = 80.5 bits (197), Expect = 4e-15
Identities = 102/393 (25%), Positives = 132/393 (33%), Gaps = 90/393 (22%)
Query: 24 TDTSEARWCSECHSNATCTEDEAVTT-----C-TCQEGFTGDGLTCVDLDECAIPGAHNC 77
T SE EC ++ C E V + C TC G C D+DEC+ GA C
Sbjct: 750 TAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECS-SGAPPC 808
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSPGL--GCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
+ C NT GSF C C G+R G C DV+EC E C C+N GS+ C
Sbjct: 809 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEG--DFCFPHGECLNTDGSFAC 866
Query: 136 VCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYAC 195
C GYR PG P G + + D C G
Sbjct: 867 TCAPGYR---------PG---------PRGASCLDVDECSEEDLCQ---------SGICT 899
Query: 196 DTDLRGWYRFVGQGGARMA---ETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWS 252
+TD G + + G R +C+ V C P + G S
Sbjct: 900 NTD--GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG----------S 947
Query: 253 GHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGR 312
C V+ C GY+ A PE C D + E + C++ G
Sbjct: 948 YRC--------VRDCDPGYH-----AGPE---GTCDDVDECQEYGPEICGAQRCENTPGS 991
Query: 313 WHC--QCKQDFNIT------DISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDS 364
+ C C + T D+ +R CGA+ + CQ F L D
Sbjct: 992 YRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAV------CQ----NLPGSFQCLCDQ 1041
Query: 365 RCSGFNDRDNRDWVSV-VTPARDGPCGTVLTRN 396
G RD R V V G CG L N
Sbjct: 1042 GYEG--ARDGRHCVDVNECETLQGVCGAALCEN 1072
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/92 (41%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 49 TCTCQEGFTGD-GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFR-LSPGLGC 106
T C G+ G C D+DEC C A++ C N PGSF C+C +G+ G C
Sbjct: 995 TPACDPGYQPTPGGGCQDVDECR--NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC 1052
Query: 107 TDVDECAEPGLSHCHALATCVNVVGSYLCVCP 138
DV+EC L A C NV GS+LCVCP
Sbjct: 1053 VDVNECET--LQGVCGAALCENVEGSFLCVCP 1082
Score = 65.9 bits (159), Expect = 1e-10
Identities = 78/303 (25%), Positives = 103/303 (33%), Gaps = 77/303 (25%)
Query: 83 CVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY 141
C++ P ++C C GFRLSP G C DVDEC + A C N GS+ CVC G+
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRR--VPPPCAPGRCENSPGSFRCVCGPGF 581
Query: 142 RG--------------------DGWHCECSPGS----CGPGLDCVPEGDALVCADPCQAH 177
R D CE +PGS C G P G + D C
Sbjct: 582 RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 641
Query: 178 RTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPS 237
L G G AC +L G +R V G R + V C P G
Sbjct: 642 PGL--------CGRG-AC-KNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG---- 687
Query: 238 SDEGIVSRKACAHWSG--HCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEG 295
C + +G HC AC G+ AP C D
Sbjct: 688 ---------RCDNTAGSFHC----------ACPAGFRSRGPGAP-------CQDVDECAR 721
Query: 296 TCEECSIDEDCKSNNGRWHCQCKQDF-------NITDISLLEHRLECGANDMKVSLGKCQ 348
+ C+ C++ G + C C F D+ E+ L C + S G Q
Sbjct: 722 SPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQ 780
Query: 349 LKS 351
++
Sbjct: 781 CRT 783
Score = 57.0 bits (136), Expect = 5e-08
Identities = 59/185 (31%), Positives = 71/185 (38%), Gaps = 25/185 (13%)
Query: 31 WCSECHSNATCTEDEAVTTCTCQEGF-----TGDGLTCVDLDECAIPGAHNCSANSSCVN 85
W S C + A C G +GD D+DEC + C + CVN
Sbjct: 1177 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVN 1235
Query: 86 TPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
T +SC C G+ + L C D DECA+ + C CVN VGSY C C D
Sbjct: 1236 TAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA-CEG-GRCVNTVGSYHCTCEPPLVLD 1293
Query: 145 GWHCECSPGSCGPGLD-----CVPE-GDALVCADPCQAHRTLDEYWRSTE----YGEGYA 194
G C LD C E G LVC +H LD TE YGE +
Sbjct: 1294 GSQRRCVSNE-SQSLDDNLGVCWQEVGADLVC-----SHPRLDRQATYTECCCLYGEAWG 1347
Query: 195 CDTDL 199
D L
Sbjct: 1348 MDCAL 1352
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 64 VDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCTDVDECAE-PGLSHCH 121
++ +EC I C+ N CV P F+C C +G+RL + C D++EC E S
Sbjct: 1495 LEAEECGI--LDGCT-NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC 1551
Query: 122 ALATCVNVVGSYLCVCPAGYRGDGWHCECSP 152
A C+N GS+ C+C G+ C+P
Sbjct: 1552 VNARCLNTDGSFRCICRPGFAPTHQPHHCAP 1582
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/84 (38%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 73 GAHNCS------ANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATC 126
G H+C NS V+ P CP GF G C DVDECA G C C
Sbjct: 283 GVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNG-SCEDVDECATGG--RCQH-GEC 335
Query: 127 VNVVGSYLCVCPAGYRGDGWHCEC 150
N G Y CVCP G+ D C
Sbjct: 336 ANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 32 CSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFS 91
C C +E + C GF +C D+DECA G C + C NT G ++
Sbjct: 287 CQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGG--RCQ-HGECANTRGGYT 343
Query: 92 CVCPEGFRL 100
CVCP+GF L
Sbjct: 344 CVCPDGFLL 352
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 37 SNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDEC-AIPGAHNCSANSSCVNTPGSFSCV 93
+N C TC C +G+ D + CVD++EC A N+ C+NT GSF C+
Sbjct: 1507 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1566
Query: 94 CPEGF 98
C GF
Sbjct: 1567 CRPGF 1571
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 101 bits (252), Expect = 2e-21
Identities = 91/318 (28%), Positives = 119/318 (37%), Gaps = 59/318 (18%)
Query: 21 TAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDEC-AIPGAHNC 77
T D E R + C C C GF C+D+DEC +P +
Sbjct: 583 TRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL 642
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAE-PGLSHCHALATCVNVVGSYLC 135
C NTPGSF CVCP G++ +P G C DVDEC + PGL C N+ GS+ C
Sbjct: 643 GR---CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC---GRGACKNLPGSFRC 696
Query: 136 VCPAGYRG-----DGWHCECSPGSCGPGLDCVPEGDALVCA-----------DPCQAHRT 179
VCPAG+RG D C P CGPG C + CA PCQ
Sbjct: 697 VCPAGFRGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGAPCQ---D 752
Query: 180 LDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSD 239
+DE RS C+ + G ++ V C + NTA G+
Sbjct: 753 VDECARSPPPCTYGRCE-NTEGSFQCV----------CPMGFQPNTA------GSECEDV 795
Query: 240 EGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEE 299
+ + AC C S Q + C G+++ H CTD
Sbjct: 796 DECENHLACP--GQECVNSPGSFQCRTCPSGHHL---------HRGRCTDVDECSSGAPP 844
Query: 300 CSIDEDCKSNNGRWHCQC 317
C C + G + C C
Sbjct: 845 CGPHGHCTNTEGSFRCSC 862
Score = 90.9 bits (224), Expect = 3e-18
Identities = 73/235 (31%), Positives = 95/235 (40%), Gaps = 49/235 (20%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSANSS 82
D +E C + C + CTC G+ G +C+D+DEC+ + +
Sbjct: 878 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS---EEDLCQSGI 934
Query: 83 CVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCHALATCVNVVGSYLCV--CPA 139
C NT GSF C+CP G R P L C DVDEC E G + C + C N GSY CV C
Sbjct: 935 CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS-QRCENSPGSYRCVRDCDP 993
Query: 140 GYRG--------------------DGWHCECSPGS------CGPGLDCVPEGDALVCADP 173
GY CE +PGS C PG P G C D
Sbjct: 994 GYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG---CQD- 1049
Query: 174 CQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFV---GQGGARMAETCVPVLRCNT 225
+DE R+ + +A +L G ++ + G GAR CV V C T
Sbjct: 1050 ------VDE-CRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1097
Score = 80.5 bits (197), Expect = 4e-15
Identities = 102/393 (25%), Positives = 132/393 (33%), Gaps = 90/393 (22%)
Query: 24 TDTSEARWCSECHSNATCTEDEAVTT-----C-TCQEGFTGDGLTCVDLDECAIPGAHNC 77
T SE EC ++ C E V + C TC G C D+DEC+ GA C
Sbjct: 787 TAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECS-SGAPPC 845
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSPGL--GCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
+ C NT GSF C C G+R G C DV+EC E C C+N GS+ C
Sbjct: 846 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEG--DFCFPHGECLNTDGSFAC 903
Query: 136 VCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYAC 195
C GYR PG P G + + D C G
Sbjct: 904 TCAPGYR---------PG---------PRGASCLDVDECSEEDLCQ---------SGICT 936
Query: 196 DTDLRGWYRFVGQGGARMA---ETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWS 252
+TD G + + G R +C+ V C P + G S
Sbjct: 937 NTD--GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG----------S 984
Query: 253 GHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGR 312
C V+ C GY+ A PE C D + E + C++ G
Sbjct: 985 YRC--------VRDCDPGYH-----AGPE---GTCDDVDECQEYGPEICGAQRCENTPGS 1028
Query: 313 WHC--QCKQDFNIT------DISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDS 364
+ C C + T D+ +R CGA+ + CQ F L D
Sbjct: 1029 YRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAV------CQ----NLPGSFQCLCDQ 1078
Query: 365 RCSGFNDRDNRDWVSV-VTPARDGPCGTVLTRN 396
G RD R V V G CG L N
Sbjct: 1079 GYEG--ARDGRHCVDVNECETLQGVCGAALCEN 1109
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/92 (41%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 49 TCTCQEGFTGD-GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFR-LSPGLGC 106
T C G+ G C D+DEC C A++ C N PGSF C+C +G+ G C
Sbjct: 1032 TPACDPGYQPTPGGGCQDVDECR--NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC 1089
Query: 107 TDVDECAEPGLSHCHALATCVNVVGSYLCVCP 138
DV+EC L A C NV GS+LCVCP
Sbjct: 1090 VDVNECET--LQGVCGAALCENVEGSFLCVCP 1119
Score = 65.9 bits (159), Expect = 1e-10
Identities = 78/303 (25%), Positives = 103/303 (33%), Gaps = 77/303 (25%)
Query: 83 CVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY 141
C++ P ++C C GFRLSP G C DVDEC + A C N GS+ CVC G+
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRR--VPPPCAPGRCENSPGSFRCVCGPGF 618
Query: 142 RG--------------------DGWHCECSPGS----CGPGLDCVPEGDALVCADPCQAH 177
R D CE +PGS C G P G + D C
Sbjct: 619 RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 678
Query: 178 RTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPS 237
L G G AC +L G +R V G R + V C P G
Sbjct: 679 PGL--------CGRG-AC-KNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG---- 724
Query: 238 SDEGIVSRKACAHWSG--HCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEG 295
C + +G HC AC G+ AP C D
Sbjct: 725 ---------RCDNTAGSFHC----------ACPAGFRSRGPGAP-------CQDVDECAR 758
Query: 296 TCEECSIDEDCKSNNGRWHCQCKQDF-------NITDISLLEHRLECGANDMKVSLGKCQ 348
+ C+ C++ G + C C F D+ E+ L C + S G Q
Sbjct: 759 SPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQ 817
Query: 349 LKS 351
++
Sbjct: 818 CRT 820
Score = 57.0 bits (136), Expect = 5e-08
Identities = 59/185 (31%), Positives = 71/185 (38%), Gaps = 25/185 (13%)
Query: 31 WCSECHSNATCTEDEAVTTCTCQEGF-----TGDGLTCVDLDECAIPGAHNCSANSSCVN 85
W S C + A C G +GD D+DEC + C + CVN
Sbjct: 1214 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVN 1272
Query: 86 TPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
T +SC C G+ + L C D DECA+ + C CVN VGSY C C D
Sbjct: 1273 TAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA-CEG-GRCVNTVGSYHCTCEPPLVLD 1330
Query: 145 GWHCECSPGSCGPGLD-----CVPE-GDALVCADPCQAHRTLDEYWRSTE----YGEGYA 194
G C LD C E G LVC +H LD TE YGE +
Sbjct: 1331 GSQRRCVSNE-SQSLDDNLGVCWQEVGADLVC-----SHPRLDRQATYTECCCLYGEAWG 1384
Query: 195 CDTDL 199
D L
Sbjct: 1385 MDCAL 1389
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 64 VDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCTDVDECAE-PGLSHCH 121
++ +EC I C+ N CV P F+C C +G+RL + C D++EC E S
Sbjct: 1532 LEAEECGI--LDGCT-NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC 1588
Query: 122 ALATCVNVVGSYLCVCPAGYRGDGWHCECSP 152
A C+N GS+ C+C G+ C+P
Sbjct: 1589 VNARCLNTDGSFRCICRPGFAPTHQPHHCAP 1619
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/84 (38%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 73 GAHNCS------ANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATC 126
G H+C NS V+ P CP GF G C DVDECA G C C
Sbjct: 320 GVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNG-SCEDVDECATGG--RCQH-GEC 372
Query: 127 VNVVGSYLCVCPAGYRGDGWHCEC 150
N G Y CVCP G+ D C
Sbjct: 373 ANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 32 CSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFS 91
C C +E + C GF +C D+DECA G C + C NT G ++
Sbjct: 324 CQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGG--RCQ-HGECANTRGGYT 380
Query: 92 CVCPEGFRL 100
CVCP+GF L
Sbjct: 381 CVCPDGFLL 389
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 37 SNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDEC-AIPGAHNCSANSSCVNTPGSFSCV 93
+N C TC C +G+ D + CVD++EC A N+ C+NT GSF C+
Sbjct: 1544 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1603
Query: 94 CPEGF 98
C GF
Sbjct: 1604 CRPGF 1608
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 101 bits (251), Expect = 2e-21
Identities = 89/331 (26%), Positives = 124/331 (37%), Gaps = 51/331 (15%)
Query: 31 WCSE---CHSNATCTEDEAVTTCTCQEGFT---GDGLTCVDLDECAIPGAHNCSANSSCV 84
+C+E C N+ C TC C+ G+ GD C D+DECA H C AN+ CV
Sbjct: 394 FCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAK-MHYCHANTVCV 452
Query: 85 NTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD 144
N PG + C C G+ CT+ DEC G +C A C N V + C C GY G+
Sbjct: 453 NLPGLYRCDCVPGYIRVDDFSCTEHDECGS-GQHNCDENAICTNTVQGHSCTCKPGYVGN 511
Query: 145 GWHCE--CSPGSCGPGLDCVPEGDALVCADPCQAH--RTLDEYWRSTEYGEGYACDTDLR 200
G C C G C G CV + + +H + +DE ++ +L
Sbjct: 512 GTICRAFCEEG-CRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLP 570
Query: 201 GWYRFVGQGG-------ARMAETCVPVLRC--------NTAAPMWLNG-------THPSS 238
GWY + G + E+C+ + C N +A + L G + PS
Sbjct: 571 GWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSC 630
Query: 239 DEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCE 298
H L + V +C G TA C +PS+ C
Sbjct: 631 SGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTA------CDCQNPSADLFCCP 684
Query: 299 ECS--IDEDCKSNNG--------RWHCQCKQ 319
EC + C NG W C+Q
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQ 715
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 100 bits (249), Expect = 4e-21
Identities = 96/334 (28%), Positives = 133/334 (39%), Gaps = 56/334 (16%)
Query: 9 MLMVVVASWFITTAATDTSEA-RWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLD 67
+L+V + + AA D E CH +A C C C+ G+TGDG C D+D
Sbjct: 13 VLLVHARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVD 72
Query: 68 ECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCTDVDECAEPGLSHCHALATC 126
EC N CVN PG++ C C +GF L+ G C DVDECAE G C +C
Sbjct: 73 EC--EREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAE-GNGGCQ--QSC 127
Query: 127 VNVVGSYLCVCPAG-YRGDGWH-CECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYW 184
VN++GSY C C G + D H C P G++C+ + CA C
Sbjct: 128 VNMMGSYECHCREGFFLSDNQHTCIQRPEE---GMNCMNKNHG--CAHIC---------- 172
Query: 185 RSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNG--THPSSDEGI 242
R T G G AC+ G+ Q + L CN + NG H D
Sbjct: 173 RETPKG-GIACEC-RPGFELTKNQRDCK--------LTCN-----YGNGGCQHTCDDTEQ 217
Query: 243 VSRKAC-----AHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTC 297
R C H G C+ +V C + C + + P TC
Sbjct: 218 GPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPD--RKTC 275
Query: 298 ---EECSI-----DEDCKSNNGRWHCQCKQDFNI 323
+EC + D C++ G + C CK+ + +
Sbjct: 276 KDIDECRLNNGGCDHICRNTVGSFECSCKKGYKL 309
Score = 81.6 bits (200), Expect = 2e-15
Identities = 51/159 (32%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 50 CTCQEGFTG--DGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCT 107
C+C++G+ + C D+DEC+ + + + CVNTPGSF C+C G+ L C
Sbjct: 301 CSCKKGYKLLINERNCQDIDECSF----DRTCDHICVNTPGSFQCLCHRGYLLYGITHCG 356
Query: 108 DVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWH---------CECSPGSCGPG 158
DVDEC+ ++ C+N GSY C CPAG W+ C+ SPG+
Sbjct: 357 DVDECS---INRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAM 413
Query: 159 LDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDT 197
L C G CA C + + +E G +C T
Sbjct: 414 LSCNRSGKKDTCALTCPSRA---RFLPESENGFTVSCGT 449
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 97.4 bits (241), Expect = 3e-20
Identities = 69/194 (35%), Positives = 91/194 (46%), Gaps = 31/194 (15%)
Query: 30 RWCSECHSNATCTEDEAVTTCTCQEGF--TGDGLTCVDLDECAIPGAHNCSANSSCVNTP 87
R C + H CT C C +GF T D TCVD+DEC + H C + C NT
Sbjct: 1205 RVCDQGH----CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDL-NPHIC-LHGDCENTK 1258
Query: 88 GSFSCVCPEGFRLSPG-LGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGW 146
GSF C C G+ + G GC+DVDEC E G +C + A+C+N+ GS+ C C G+ GDG+
Sbjct: 1259 GSFVCHCQLGYMVRKGATGCSDVDEC-EVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGF 1317
Query: 147 HC----EC--SPGSCGPGLDC--VP-----------EGDALVC--ADPCQAHRTLDEYWR 185
C EC C P DC VP GD C D C + L + +
Sbjct: 1318 ECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQ 1377
Query: 186 STEYGEGYACDTDL 199
GY C+ ++
Sbjct: 1378 CLNAPGGYRCECEM 1391
Score = 95.5 bits (236), Expect = 1e-19
Identities = 90/364 (24%), Positives = 128/364 (35%), Gaps = 52/364 (14%)
Query: 24 TDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGL---TCVDLDECAIPGAHNCSAN 80
TD E R + TC C C G+ + C+D+DECA
Sbjct: 1027 TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPL--LCRG 1084
Query: 81 SSCVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPA 139
+C NT GS+ C CP G L+ G C D+DEC+ H CVNV+G++ C C A
Sbjct: 1085 GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHG--QCVNVIGAFQCSCHA 1142
Query: 140 GYR-------------------GDGWHCECSPGS----CGPGLDCVPEGDALVCADPCQA 176
G++ G HC + GS CG G +P+G A D C+
Sbjct: 1143 GFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEE 1202
Query: 177 HRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHP 236
+ + + T G+ C + G TCV V C+ + L+G
Sbjct: 1203 NPRVCDQGHCTNMPGGHRC-------LCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 237 SSDEGIVSRKACAHW-----SGHCCLWDASVQVKACAGGYYVYNLTAPPECHLA------ 285
++ V + +G + + V C N+ C
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGD 1315
Query: 286 --YCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVS 343
C D CS DC + G + C C+Q F D E R EC N
Sbjct: 1316 GFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF-AGDGFFCEDRDECAENVDLCD 1374
Query: 344 LGKC 347
G+C
Sbjct: 1375 NGQC 1378
Score = 92.4 bits (228), Expect = 1e-18
Identities = 92/348 (26%), Positives = 129/348 (37%), Gaps = 71/348 (20%)
Query: 37 SNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
+N C + C C G++ D G+ CVD DEC++ H C +C N G F C C
Sbjct: 2096 TNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV--GHPCG-QGTCTNVIGGFECAC 2152
Query: 95 PEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY--RGDGWHC---- 148
+GF + C D+DEC+ L+ C N GSYLC CPAGY R DG C
Sbjct: 2153 ADGFEPGLMMTCEDIDECS---LNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 149 ECSPGS--------------------CGPGLDCVP-EGDALVCADPCQAHRTLDEYWRST 187
EC+ G C PG+ +P G+ + C A L R
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCV 2269
Query: 188 EYGEGYACDTDLRGWY--------RFVGQGG--ARMAETCVPVLRCNTAAPMWL------ 231
+ CD D G+ + QG A + +T L ++ A
Sbjct: 2270 NTAGSFRCDCD-EGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGG 2328
Query: 232 -NGTHPSSD-----EGIVSRKACAHWSGHCC----LWDASVQVKACAGGYYVYNLTAPPE 281
G P + RK C H SG+ + + + CA G + N
Sbjct: 2329 GRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECI-NSLGSFR 2387
Query: 282 CHLAYCTDPSSVEGTC---EECSIDED-----CKSNNGRWHCQCKQDF 321
CH P + TC +ECS CK+ G + C C + +
Sbjct: 2388 CHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGY 2435
Score = 88.2 bits (217), Expect = 2e-17
Identities = 53/147 (36%), Positives = 70/147 (47%), Gaps = 14/147 (9%)
Query: 35 CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
C C CTC++GF GDG C D DECA C N C+N PG + C C
Sbjct: 1332 CSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECA-ENVDLCD-NGQCLNAPGGYRCEC 1389
Query: 95 PEGF-RLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGD--GWHC--- 148
GF C DVDECA+ L A +C N+ G + C+C GY D G +C
Sbjct: 1390 EMGFDPTEDHRACQDVDECAQGNLC---AFGSCENLPGMFRCICNGGYELDRGGGNCTDI 1446
Query: 149 -ECS-PGSCGPGLDCVPEGDALVCADP 173
EC+ P +C G+ C+ + +C+ P
Sbjct: 1447 NECADPVNCINGV-CINTPGSYLCSCP 1472
Score = 87.4 bits (215), Expect = 4e-17
Identities = 86/336 (25%), Positives = 114/336 (33%), Gaps = 87/336 (25%)
Query: 20 TTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGL--TCVDLDECA-IPGAHN 76
T D E R + ++ C C CQ G+T D TC+D+DEC+ +P
Sbjct: 2358 TAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP-- 2415
Query: 77 CSANSSCVNTPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
C NT GSF C CP G+ L G C D+DEC +C L CVN VG++ C
Sbjct: 2416 --CTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS-RQHNCQFL--CVNTVGAFTC 2470
Query: 136 VCPAGYRG------DGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEY 189
CP G+ D C PG CG C + C+ H+ T
Sbjct: 2471 RCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF----RCECHQGF------TLV 2520
Query: 190 GEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
G+ C+ C RC L G S +G
Sbjct: 2521 SSGHGCED----------------VNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQ-- 2562
Query: 250 HWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTD---------PSSVE-----G 295
W V CA +PP C A C + PS + G
Sbjct: 2563 --------WAQCVDENECA--------LSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 296 TCEECSIDE----------DCKSNNGRWHCQCKQDF 321
C+E +DE C + G + C C Q +
Sbjct: 2607 GCQE--VDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 86.7 bits (213), Expect = 6e-17
Identities = 93/361 (25%), Positives = 131/361 (36%), Gaps = 90/361 (24%)
Query: 38 NATCTEDEAVTTCTCQEGFTGDGL-TCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPE 96
N C + C C G+T D C+D+DEC H + CVN PG++ C C
Sbjct: 421 NGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCH----HGDCVNIPGTYHCRCYP 476
Query: 97 GFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC----E 149
GF+ +P C DVDEC G CH L CVN GS+ CVC AG+ DG +C E
Sbjct: 477 GFQATPTRQACVDVDECIVSG-GLCH-LGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNE 534
Query: 150 CSPGS-----------------CGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEG 192
C+ + C PG P G + D CQ G
Sbjct: 535 CATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGIC---------VNG 585
Query: 193 YACDTDLRGWYRFVGQGGARM---AETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACA 249
+ +T+ G +R GG + CV +T G+ G V++ C
Sbjct: 586 HCTNTE--GSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECC 643
Query: 250 -----HWSGH----CCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC 300
H G C D++ C+ G L TD + EC
Sbjct: 644 CANPDHGFGEPCQLCPAKDSAEFQALCSSG-------------LGITTDGRDI----NEC 686
Query: 301 SIDED------CKSNNGRWHCQCKQDF-------NITDISLLEHRLECGANDMKVSLGKC 347
++D + C++ G + C C + + TD+ EC N + G C
Sbjct: 687 ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVD------ECALNSLLCDNGWC 740
Query: 348 Q 348
Q
Sbjct: 741 Q 741
Score = 81.6 bits (200), Expect = 2e-15
Identities = 49/129 (37%), Positives = 64/129 (49%), Gaps = 10/129 (7%)
Query: 50 CTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGL-GC 106
C+C +GFT CVD +ECA+ + ++SC NT G F CVCP GF L GC
Sbjct: 2551 CSCPQGFTQHSQWAQCVDENECAL--SPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGC 2608
Query: 107 TDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY-RGDGWHCECSPGSCGPGLDCVPEG 165
+VDECA +C N G +LC CP GY R HC G PG P+
Sbjct: 2609 QEVDECAG---RRGPCSYSCANTPGGFLCGCPQGYFRAGQGHCVSGLG-FSPGPQDTPDK 2664
Query: 166 DALVCADPC 174
+ L+ ++ C
Sbjct: 2665 EELLSSEAC 2673
Score = 81.3 bits (199), Expect = 3e-15
Identities = 94/344 (27%), Positives = 127/344 (36%), Gaps = 51/344 (14%)
Query: 19 ITTAATDTSEAR-WCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCV--DLDECA-IPGA 74
+T A+ S R W + C E T C EGF + +T + D+DEC +PG
Sbjct: 1514 VTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 75 HNCSANSSCVNTPGSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSY 133
CVNT GSF C CP G+ LS C D+DEC+ S TC N +G+Y
Sbjct: 1574 ---CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTH--SGICGPGTCYNTLGNY 1628
Query: 134 LCVCPAGYR--GDGWHC-ECSPGSCGPGLD--CVPEGDALVCADPCQAHRTLDEYW-RST 187
CVCPA Y G +C + C + C E V C + + W R
Sbjct: 1629 TCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPC 1688
Query: 188 EYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSS----DEGIV 243
E AC T + Y+ + C AP +L H DE
Sbjct: 1689 E-----ACPTPISPDYQIL----------------CGNQAPGFLTDIHTGKPLDIDECGE 1727
Query: 244 SRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSID 303
CA +G C S + + AG Y L A C D C +
Sbjct: 1728 IPAICA--NGICINQIGSFRCECPAGFNYNSILLA--------CEDVDECGSRESPCQQN 1777
Query: 304 EDCKSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKC 347
DC + G + C+C + + ++ R EC S G C
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDC 1821
Score = 81.3 bits (199), Expect = 3e-15
Identities = 44/130 (33%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 37 SNATCTEDEAVTTCTCQEGFTGDG--LTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
+N C C C GF + L C D+DEC + C N+ C+N PGS+ C C
Sbjct: 1733 ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESP-CQQNADCINIPGSYRCKC 1791
Query: 95 PEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYR--GDGWHC---- 148
G++LSPG C +EC E + + + C++ GSY+C+C G++ D C
Sbjct: 1792 TRGYKLSPGGACVGRNECRE--IPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDID 1849
Query: 149 ECSPGSCGPG 158
EC CG G
Sbjct: 1850 ECDRQPCGNG 1859
Score = 79.0 bits (193), Expect = 1e-14
Identities = 88/317 (27%), Positives = 123/317 (38%), Gaps = 43/317 (13%)
Query: 33 SECHSNATCTEDEAVTTCTCQEGF--TGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSF 90
S CH + C C C GF T CVD+DEC + G C CVNT GSF
Sbjct: 456 SPCH-HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGL-CHLGR-CVNTEGSF 512
Query: 91 SCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY--RGDGWH 147
CVC GF LSP G C D +ECA S C+N GS+ C+C G+ G +
Sbjct: 513 QCVCNAGFELSPDGKNCVDHNECA---TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHY 569
Query: 148 C----EC-SPGSCGPGLDCVPEGDALVC------ADPCQAHRTLDEYWRSTEYG--EGYA 194
C EC +PG C G C + C A +D + RST YG E +
Sbjct: 570 CMDIDECQTPGICVNG-HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGS 628
Query: 195 CDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSGH 254
C G +E C P L S++ + +
Sbjct: 629 CARPF--------PGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDG 680
Query: 255 CCLWDASVQVKACAGGYYVYNLTAPPE--CHLAYCTDPSSVEGT-CEECSIDE------D 305
+ + ++ + CA G NL C+L Y S + T +EC+++
Sbjct: 681 RDINECALDPEVCANG-VCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGW 739
Query: 306 CKSNNGRWHCQCKQDFN 322
C+++ G + C C F+
Sbjct: 740 CQNSPGSYSCSCPPGFH 756
Score = 78.2 bits (191), Expect = 2e-14
Identities = 52/143 (36%), Positives = 63/143 (44%), Gaps = 12/143 (8%)
Query: 19 ITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTG--DGLTCVDLDECAIPGAHN 76
ITT D +E E +N C C C G+ G C D+DECA+
Sbjct: 676 ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSL-- 733
Query: 77 CSANSSCVNTPGSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSYLC 135
N C N+PGS+SC CP GF C DVDEC LS C N+ GSY C
Sbjct: 734 LCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC----LSSPCVSGVCRNLAGSYTC 789
Query: 136 VCPAGYRGD--GWHC-ECSPGSC 155
C G R D G C + + G+C
Sbjct: 790 KCGPGSRLDPSGTFCLDSTKGTC 812
Score = 74.3 bits (181), Expect = 3e-13
Identities = 47/147 (31%), Positives = 65/147 (44%), Gaps = 15/147 (10%)
Query: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGF--TGDGLTCVDLDECAIPGAHNCSA 79
A +E R S+ C + E C C GF + D C+D+DEC
Sbjct: 1802 ACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECD----RQPCG 1857
Query: 80 NSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPA 139
N +C N GS++C+C GF ++ C D DEC C C+N GS+ C+C
Sbjct: 1858 NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCR-FGHCLNTAGSFHCLCQD 1916
Query: 140 GYR--GDGWHC----EC--SPGSCGPG 158
G+ DG +C EC G+C PG
Sbjct: 1917 GFELTADGKNCVDTNECLSLAGTCLPG 1943
Score = 70.5 bits (171), Expect = 5e-12
Identities = 51/176 (28%), Positives = 69/176 (39%), Gaps = 41/176 (23%)
Query: 33 SECHSNATCTEDEAVTTCTCQEGF-TGDGLTCVDLDEC-AIPGAHNCSANSSCVNTPGSF 90
S C NA C C C G+ G CV +EC IP N ++ C++T GS+
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIP---NVCSHGDCMDTEGSY 1828
Query: 91 SCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY----RGD- 144
C+C GF+ S C D+DEC + TC N++GSY C+C G+ GD
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECDRQPCGN----GTCKNIIGSYNCLCFPGFVVTHNGDC 1884
Query: 145 ------------------------GWHCECSPG--SCGPGLDCVPEGDALVCADPC 174
+HC C G G +CV + L A C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC 1940
Score = 61.6 bits (148), Expect = 2e-09
Identities = 48/140 (34%), Positives = 61/140 (43%), Gaps = 14/140 (10%)
Query: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD--GLTCVDLDECAIPGAHNCSA 79
A D E + C + +C + C C G+ D G C D++ECA P NC
Sbjct: 1401 ACQDVDECAQGNLC-AFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPV--NC-I 1456
Query: 80 NSSCVNTPGSFSCVCPEGFRLSP-GLGCTDVD------ECAEPGLSHCHALATCVNVVGS 132
N C+NTPGS+ C CP+ F L+P G+GC D E + G S A V
Sbjct: 1457 NGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTR 1516
Query: 133 YLCVCPAGYRGDGWHCECSP 152
C C G R G CE P
Sbjct: 1517 ASCCCSLG-RAWGNPCELCP 1535
Score = 60.1 bits (144), Expect = 6e-09
Identities = 97/391 (24%), Positives = 131/391 (33%), Gaps = 84/391 (21%)
Query: 26 TSEARWCSECHSNATCTEDEAVTTCTCQEGFTG-DGLTCVDLDEC-AIPGAHNCSANSSC 83
T A W S C C D A C GF G+TC D++EC + PG N C
Sbjct: 837 TLGAAWGSPCER---CEIDPA-----CARGFARMTGVTCDDVNECESFPGV---CPNGRC 885
Query: 84 VNTPGSFSCVCPEGFRL-SPGLGCTDV-----------DECAE--PGLSHCHALATCVNV 129
VNT GSF C CPEG L + G C DV DEC PG +
Sbjct: 886 VNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGA 945
Query: 130 VGSYLC-------------VCPAG-------------YRGDGWHCECSPGSCGPGLDCVP 163
V C +CP G + D C+ PG C G C
Sbjct: 946 VWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHG-TCRN 1004
Query: 164 EGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVG-------------QGG 210
+ CA C LD R+ + DL G V + G
Sbjct: 1005 TVGSFHCA--CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Query: 211 ARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAH---WSGHCC--LWDASVQVK 265
+ + C+ V C + GT ++D + H G C + + S+
Sbjct: 1063 FMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDG 1122
Query: 266 ACAGGYYVYNLTA-PPECHLAYCTDPSSVEGTCE--ECSI-----DEDCKSNNGRWHCQC 317
C G V + A CH + + P +G + EC + D C + G + C C
Sbjct: 1123 LCPHGQCVNVIGAFQCSCHAGFQSTPDR-QGCVDINECRVQNGGCDVHCINTEGSYRCSC 1181
Query: 318 KQDFNI-TDISLLEHRLECGANDMKVSLGKC 347
Q +++ D EC N G C
Sbjct: 1182 GQGYSLMPDGRACADVDECEENPRVCDQGHC 1212
Score = 60.1 bits (144), Expect = 6e-09
Identities = 44/127 (34%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 34 ECHSNAT-CTEDEAVTTCTCQEGFT---GDGLTCVDLDECAIPGAHNCSANSSCVNTPGS 89
+CH+ C C C G G G C D +EC + N CVNT GS
Sbjct: 2217 DCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH--AQPDLCVNGRCVNTAGS 2274
Query: 90 FSCVCPEGFRLSPGL-GCTDVDE---CAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDG 145
F C C EGF+ SP L C D+ + AE + C +L++ V C C G RG G
Sbjct: 2275 FRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGG-RGWG 2333
Query: 146 WHCECSP 152
CE P
Sbjct: 2334 PRCELCP 2340
Score = 56.6 bits (135), Expect = 7e-08
Identities = 44/148 (29%), Positives = 56/148 (37%), Gaps = 19/148 (12%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCV 84
DT+E + TC E C C GF C+D+DEC+ N +C
Sbjct: 1929 DTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECS--EEPNLCLFGTCT 1986
Query: 85 NTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRG 143
N+PGSF C+CP GF LS G C D + + C + C P +
Sbjct: 1987 NSPGSFQCLCPPGFVLSDNGHRCFDTRQ------------SFCFTRFEAGKCSVPKAFNT 2034
Query: 144 DGWHCECS----PGSCGPGLDCVPEGDA 167
C CS G P C EG A
Sbjct: 2035 TKTRCCCSKRPGEGWGDPCELCPQEGSA 2062
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/122 (32%), Positives = 48/122 (39%), Gaps = 23/122 (18%)
Query: 52 CQEGFTGDGLT--CVDLDEC-AIPGAHNCSANSSCVNTPGSFSCVCPEGFRLS-PGLGCT 107
C+ GF + T C D+DEC A+PG SCVN GSF C CP G RLS C
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL---CQGGSCVNMVGSFHCRCPVGHRLSDSSAACE 288
Query: 108 DVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSC---GPGLD-CVP 163
D + C +V+ C C C G C GP + C P
Sbjct: 289 D------------YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPP 336
Query: 164 EG 165
G
Sbjct: 337 RG 338
Score = 43.5 bits (101), Expect = 6e-04
Identities = 47/172 (27%), Positives = 60/172 (34%), Gaps = 63/172 (36%)
Query: 27 SEARWCS-ECHSNATCTEDEAVTTCTCQEGFTG-------------DGLTCVDLDECAI- 71
S CS C + TC +C CQ+G+TG +G C+ + CA
Sbjct: 115 SRGSGCSVSCMNGGTCRG----ASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACV 170
Query: 72 -----PGAHNCSANSSCVNTPGSFSC---------------------------VCP---- 95
P C G C +CP
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 96 ---EGFRLSPGLG-CTDVDEC-AEPGLSHCHALATCVNVVGSYLCVCPAGYR 142
GF + G C DVDEC A PGL C +CVN+VGS+ C CP G+R
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGL--CQG-GSCVNMVGSFHCRCPVGHR 279
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 21/116 (18%)
Query: 35 CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVC 94
C S ++ +E C C G G G C + C +PG ++ +C
Sbjct: 2309 CRSLSSSSEAVTRAECCCGGG-RGWGPRC---ELCPLPGT-------------SAYRKLC 2351
Query: 95 PEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCEC 150
P G + DVDEC L+H A C+N +GS+ C C AGY D C
Sbjct: 2352 PHGSGYTAE--GRDVDECRM--LAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 33.5 bits (75), Expect = 0.62
Identities = 35/131 (26%), Positives = 46/131 (35%), Gaps = 27/131 (20%)
Query: 52 CQEGFTGDGLTCVDLD-----ECAIPGAHNCSANSSCVN--TPGSFSCVCPEGFRLSPGL 104
C EGF C D C + CS SC+N T SC+C +G+ +
Sbjct: 90 CGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSV--SCMNGGTCRGASCLCQKGYTGT--- 144
Query: 105 GCTDVDECAEPGLSH-CHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSC----GPGL 159
C +P CH C +G C C G+ G + G C GP
Sbjct: 145 ------VCGQPICDRGCHNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPE- 194
Query: 160 DCVPEGDALVC 170
C + LVC
Sbjct: 195 GCQHQLTGLVC 205
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 97.4 bits (241), Expect = 3e-20
Identities = 57/163 (34%), Positives = 73/163 (44%), Gaps = 29/163 (17%)
Query: 22 AATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANS 81
+ TD +E S C ++ C +C+CQ GF TC D+DECA P A C ++
Sbjct: 129 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRA--CPEHA 186
Query: 82 SCVNTPGSFSCVCPEGFRLSPG--------LGCTDVDECAEPGLSHCHALATCVNVVGSY 133
+C NT G++SC C GF S G C D+DEC E C +TC N GSY
Sbjct: 187 TCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTE----MCPINSTCTNTPGSY 242
Query: 134 LCVCPAG---------YRGDGWHC----EC--SPGSCGPGLDC 161
C C G + G C EC P +CGP C
Sbjct: 243 FCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSIC 285
Score = 80.5 bits (197), Expect = 4e-15
Identities = 55/177 (31%), Positives = 70/177 (39%), Gaps = 40/177 (22%)
Query: 24 TDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGD---------GLTCVDLDECAIPGA 74
T + R + C + ATCT C C++GF G+ C D+DEC+
Sbjct: 30 TKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECS-QSP 88
Query: 75 HNCSANSSCVNTPGSFSCVCPEGFRLSPG----------LGCTDVDECAEPGLSHCHALA 124
C NSSC N G + C C +GF G CTD++EC S C +
Sbjct: 89 QPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTS--SVCPEHS 146
Query: 125 TCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADP--CQAHRT 179
CVN +GSY C C G+ CE D CADP C H T
Sbjct: 147 DCVNSMGSYSCSCQVGFISRNSTCE----------------DVDECADPRACPEHAT 187
Score = 58.5 bits (140), Expect = 2e-08
Identities = 32/81 (39%), Positives = 38/81 (46%), Gaps = 11/81 (13%)
Query: 32 CSE-CHSNATCTEDEAVTTCTCQEGF---------TGDGLTCVDLDECAIPGAHNCSANS 81
C+E C N+TCT CTC GF T G+ C D+DEC C NS
Sbjct: 225 CTEMCPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECR-QDPSTCGPNS 283
Query: 82 SCVNTPGSFSCVCPEGFRLSP 102
C N GS+SC C GF +P
Sbjct: 284 ICTNALGSYSCGCIAGFHPNP 304
Score = 56.6 bits (135), Expect = 7e-08
Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 20/128 (15%)
Query: 77 CSANSSCVNTPGSFSCVCPEGFRLS--------PGLGCTDVDECAEPGLSHCHALATCVN 128
C A ++C NT S+ C C +GF S PG+ C D+DEC++ C ++C N
Sbjct: 41 CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQ-SPQPCGPNSSCKN 99
Query: 129 VVGSYLCVCPAGY---RGDGWHCECSPGSCGPGLDCVPEGDAL---VCADPCQAHRTLDE 182
+ G Y C C G+ G+ W PG G C + L VC + ++
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDW----VPGKPG-NFSCTDINECLTSSVCPEHSDCVNSMGS 154
Query: 183 YWRSTEYG 190
Y S + G
Sbjct: 155 YSCSCQVG 162
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 96.7 bits (239), Expect = 6e-20
Identities = 56/164 (34%), Positives = 67/164 (40%), Gaps = 54/164 (32%)
Query: 35 CHSNATCTEDEAVT-TCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCV 93
C + A C V TC C G+ GDG CVD +ECA G H C NS C+N PGS+ C
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECAT-GFHRCGPNSVCINLPGSYRCE 828
Query: 94 CPEGFRLS--------------------------------------------PGLG---- 105
C G+ + PG
Sbjct: 829 CRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGH 888
Query: 106 -CTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC 148
CTDVDEC+E + CH ATC N GS+ C C GY GDG+ C
Sbjct: 889 QCTDVDECSE---NRCHPAATCYNTPGSFSCRCQPGYYGDGFQC 929
Score = 40.8 bits (94), Expect = 0.004
Identities = 46/164 (28%), Positives = 57/164 (34%), Gaps = 33/164 (20%)
Query: 24 TDTSEARWCSE--CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANS 81
TD E CSE CH ATC +C CQ G+ GDG C+ +S
Sbjct: 891 TDVDE---CSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCI--------------PDS 933
Query: 82 SCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGY 141
+ TP + PG + +C E G C G CV P G+
Sbjct: 934 TSSLTPCEQQQRHAQAQYAYPG-ARFHIPQCDEQG---NFLPLQCHGSTGFCWCVDPDGH 989
Query: 142 RGDGWHCECSPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWR 185
G + PGS P PE P Q T+ E WR
Sbjct: 990 EVPG--TQTPPGSTPPHCGPSPE--------PTQRPPTICERWR 1023
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 94.7 bits (234), Expect = 2e-19
Identities = 107/359 (29%), Positives = 138/359 (38%), Gaps = 49/359 (13%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFTG--DGLTCVDLDECAIPGAHNCSANSS 82
D E S C E C C GF +G C+D+DEC P +
Sbjct: 916 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP---DVCGEGH 972
Query: 83 CVNTPGSFSC-VCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCV-CPAG 140
CVNT G+F C C G+R++ C D+DEC P S C CVN GSY CV C G
Sbjct: 973 CVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP--STCPD-EQCVNSPGSYQCVPCTEG 1029
Query: 141 YRGDGWHC----EC-SPGSCGPGLDCVPEGDALVCA-------DPCQAH-RTLDEYWRST 187
+RG C EC P C G DC + +C+ P H R +DE +
Sbjct: 1030 FRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 1088
Query: 188 EYGEGYACDTDLRGWYRFV-GQGGARMA--ETCVPVLRC---NTAAPMWLNGTHPSSDEG 241
G +T+ G +R GQG A + C + C + A T S
Sbjct: 1089 LCVNGQCKNTE--GSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV 1146
Query: 242 IVSRKACAHWSGHC-----CLWDASV-QVKACAGGYYVYNLTAPPECHL---AYCTDPSS 292
+ HC CL D SV Q C Y+ T P L C D +
Sbjct: 1147 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINE 1206
Query: 293 VEGTCEE---CSIDEDCKSNNGRWHCQCKQDFNIT-DISLLEHRLECGANDMKVSLGKC 347
CE C +C + G +HC C+Q F+I+ D E EC N + S G C
Sbjct: 1207 ----CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFC 1261
Score = 94.0 bits (232), Expect = 4e-19
Identities = 60/171 (35%), Positives = 78/171 (45%), Gaps = 21/171 (12%)
Query: 33 SEC-HSNATCTEDEAVTT-----CTCQEGFT-GDGLTCVDLDECAIPGAHNCSANSSCVN 85
+EC + C + + T CTC +GF D TC D++EC PG C C+N
Sbjct: 1164 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGL--CGPQGECLN 1221
Query: 86 TPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRG- 143
T GSF CVC +GF +S G C D+DEC + H C N GS+ C+C G++
Sbjct: 1222 TEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGF--CDNTAGSFRCLCYQGFQAP 1279
Query: 144 -------DGWHCECSPGSCGPGLDCVPEGDAL-VCADPCQAHRTLDEYWRS 186
D CE G CG EG L VCAD Q + + RS
Sbjct: 1280 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1330
Score = 88.2 bits (217), Expect = 2e-17
Identities = 81/307 (26%), Positives = 120/307 (39%), Gaps = 59/307 (19%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHAL 123
+++EC + C A C+N P ++C+C EG+R S C D+DEC + + H +
Sbjct: 874 EINECTV-NPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ--VQHLCSQ 929
Query: 124 ATCVNVVGSYLCVCPAGYRG--DGWHC----EC-SPGSCGPGLDCVPEGDALVCADPCQA 176
C N GS+LC+CPAG+ +G +C EC P CG G CV A C
Sbjct: 930 GRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG-HCVNTVGAFRC------ 982
Query: 177 HRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHP 236
EY CD+ YR +G + C+ C P P
Sbjct: 983 -----EY-----------CDSG----YRMTQRGRCEDIDECLNPSTC----PDEQCVNSP 1018
Query: 237 SSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAP--PECHLAYCTDPSSVE 294
S + + + W+G C D ++ CA G NL CH Y P
Sbjct: 1019 GSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMCSCHKGYTRTPDHKH 1077
Query: 295 -GTCEECS-----IDEDCKSNNGRWHCQCKQDFNIT-------DISLLEHRLECGANDMK 341
+EC ++ CK+ G + C C Q + ++ DI +HR C +
Sbjct: 1078 CRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCR 1137
Query: 342 VSLGKCQ 348
+ G Q
Sbjct: 1138 NTEGSFQ 1144
Score = 84.7 bits (208), Expect = 2e-16
Identities = 48/116 (41%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSS 82
D +E C C E C CQ+GF+ DG TC D+DEC C ++
Sbjct: 1203 DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV--CDSHGF 1260
Query: 83 CVNTPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
C NT GSF C+C +GF+ G GC DV+EC LS A C NV GS+LCVC
Sbjct: 1261 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECEL--LSGVCGEAFCENVEGSFLCVC 1314
Score = 54.7 bits (130), Expect = 3e-07
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHAL 123
D DEC + G C N C+NT + C C +G P L C D+DEC +P S C
Sbjct: 1425 DADECLLFGQEICK-NGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP--SSC-ID 1480
Query: 124 ATCVNVVGSYLCVC 137
CVN GSY C C
Sbjct: 1481 GQCVNTEGSYNCFC 1494
Score = 49.7 bits (117), Expect = 8e-06
Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 67 DECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPG-LGCTDVDECAEPG--LSHCHAL 123
+EC G N N CV ++C C +G+ L + C DV+EC E +S C
Sbjct: 1624 EEC---GILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN- 1679
Query: 124 ATCVNVVGSYLCVCPAGYRGDGWHCECSP 152
A C+N GSY C+C GY C+P
Sbjct: 1680 AKCINTDGSYKCLCLPGYVPSDKPNYCTP 1708
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
Query: 17 WFITTAATDTSEARWCSECH-----SNATCTEDEAVTTCTCQEGFTGDG--LTCVDLDEC 69
+FI ++ E EC N C + TC C +G+ D +TCVD++EC
Sbjct: 1608 YFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNEC 1667
Query: 70 -AIPGAHNCSANSSCVNTPGSFSCVCPEGF 98
+ + N+ C+NT GS+ C+C G+
Sbjct: 1668 DELNNRMSLCKNAKCINTDGSYKCLCLPGY 1697
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 13/99 (13%)
Query: 63 CVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCH 121
C D++EC + G N C+NT GS+ C C GF P C C+
Sbjct: 624 CQDINECQLQGV---CPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCY 680
Query: 122 ALAT----CVNVVGSY----LCVCPAGYRGDGWHCECSP 152
L + C++ + + LC C G + G HCE P
Sbjct: 681 RLVSSGRQCMHPLSVHLTKQLCCCSVG-KAWGPHCEKCP 718
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 34 ECHSNATCTEDEAVTTCTCQEGFTGDG--LTCVDLDECAIPGAHNCSANSSCVNTPGSFS 91
E N C C C++G D L C D+DEC P + + CVNT GS++
Sbjct: 1435 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSS---CIDGQCVNTEGSYN 1491
Query: 92 CVC 94
C C
Sbjct: 1492 CFC 1494
Score = 38.9 bits (89), Expect = 0.015
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 11/92 (11%)
Query: 94 CPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPG 153
C G++ C D++EC G+ C+N +GSY C C G+ D C P
Sbjct: 612 CLPGYKRVNNTFCQDINECQLQGVC---PNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD 668
Query: 154 ------SCGPGLDCVPEGDALVCADPCQAHRT 179
GP V G C P H T
Sbjct: 669 PPVISEEKGPCYRLVSSGRQ--CMHPLSVHLT 698
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 94.7 bits (234), Expect = 2e-19
Identities = 107/359 (29%), Positives = 138/359 (38%), Gaps = 49/359 (13%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFTG--DGLTCVDLDECAIPGAHNCSANSS 82
D E S C E C C GF +G C+D+DEC P +
Sbjct: 590 DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP---DVCGEGH 646
Query: 83 CVNTPGSFSC-VCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCV-CPAG 140
CVNT G+F C C G+R++ C D+DEC P S C CVN GSY CV C G
Sbjct: 647 CVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNP--STCPD-EQCVNSPGSYQCVPCTEG 703
Query: 141 YRGDGWHC----EC-SPGSCGPGLDCVPEGDALVCA-------DPCQAH-RTLDEYWRST 187
+RG C EC P C G DC + +C+ P H R +DE +
Sbjct: 704 FRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN 762
Query: 188 EYGEGYACDTDLRGWYRFV-GQGGARMA--ETCVPVLRC---NTAAPMWLNGTHPSSDEG 241
G +T+ G +R GQG A + C + C + A T S
Sbjct: 763 LCVNGQCKNTE--GSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV 820
Query: 242 IVSRKACAHWSGHC-----CLWDASV-QVKACAGGYYVYNLTAPPECHL---AYCTDPSS 292
+ HC CL D SV Q C Y+ T P L C D +
Sbjct: 821 CDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINE 880
Query: 293 VEGTCEE---CSIDEDCKSNNGRWHCQCKQDFNIT-DISLLEHRLECGANDMKVSLGKC 347
CE C +C + G +HC C+Q F+I+ D E EC N + S G C
Sbjct: 881 ----CEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFC 935
Score = 94.0 bits (232), Expect = 4e-19
Identities = 60/171 (35%), Positives = 78/171 (45%), Gaps = 21/171 (12%)
Query: 33 SEC-HSNATCTEDEAVTT-----CTCQEGFT-GDGLTCVDLDECAIPGAHNCSANSSCVN 85
+EC + C + + T CTC +GF D TC D++EC PG C C+N
Sbjct: 838 NECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGL--CGPQGECLN 895
Query: 86 TPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRG- 143
T GSF CVC +GF +S G C D+DEC + H C N GS+ C+C G++
Sbjct: 896 TEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGF--CDNTAGSFRCLCYQGFQAP 953
Query: 144 -------DGWHCECSPGSCGPGLDCVPEGDAL-VCADPCQAHRTLDEYWRS 186
D CE G CG EG L VCAD Q + + RS
Sbjct: 954 QDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS 1004
Score = 88.2 bits (217), Expect = 2e-17
Identities = 81/307 (26%), Positives = 120/307 (39%), Gaps = 59/307 (19%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLG-CTDVDECAEPGLSHCHAL 123
+++EC + C A C+N P ++C+C EG+R S C D+DEC + + H +
Sbjct: 548 EINECTV-NPDICGAGH-CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ--VQHLCSQ 603
Query: 124 ATCVNVVGSYLCVCPAGYRG--DGWHC----EC-SPGSCGPGLDCVPEGDALVCADPCQA 176
C N GS+LC+CPAG+ +G +C EC P CG G CV A C
Sbjct: 604 GRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEG-HCVNTVGAFRC------ 656
Query: 177 HRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHP 236
EY CD+ YR +G + C+ C P P
Sbjct: 657 -----EY-----------CDSG----YRMTQRGRCEDIDECLNPSTC----PDEQCVNSP 692
Query: 237 SSDEGIVSRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAP--PECHLAYCTDPSSVE 294
S + + + W+G C D ++ CA G NL CH Y P
Sbjct: 693 GSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMCSCHKGYTRTPDHKH 751
Query: 295 -GTCEECS-----IDEDCKSNNGRWHCQCKQDFNIT-------DISLLEHRLECGANDMK 341
+EC ++ CK+ G + C C Q + ++ DI +HR C +
Sbjct: 752 CRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCR 811
Query: 342 VSLGKCQ 348
+ G Q
Sbjct: 812 NTEGSFQ 818
Score = 84.7 bits (208), Expect = 2e-16
Identities = 48/116 (41%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGFT--GDGLTCVDLDECAIPGAHNCSANSS 82
D +E C C E C CQ+GF+ DG TC D+DEC C ++
Sbjct: 877 DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTV--CDSHGF 934
Query: 83 CVNTPGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
C NT GSF C+C +GF+ G GC DV+EC LS A C NV GS+LCVC
Sbjct: 935 CDNTAGSFRCLCYQGFQAPQDGQGCVDVNECEL--LSGVCGEAFCENVEGSFLCVC 988
Score = 54.7 bits (130), Expect = 3e-07
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 65 DLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSP-GLGCTDVDECAEPGLSHCHAL 123
D DEC + G C N C+NT + C C +G P L C D+DEC +P S C
Sbjct: 1099 DADECLLFGQEICK-NGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP--SSC-ID 1154
Query: 124 ATCVNVVGSYLCVC 137
CVN GSY C C
Sbjct: 1155 GQCVNTEGSYNCFC 1168
Score = 49.7 bits (117), Expect = 8e-06
Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 67 DECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPG-LGCTDVDECAEPG--LSHCHAL 123
+EC G N N CV ++C C +G+ L + C DV+EC E +S C
Sbjct: 1298 EEC---GILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKN- 1353
Query: 124 ATCVNVVGSYLCVCPAGYRGDGWHCECSP 152
A C+N GSY C+C GY C+P
Sbjct: 1354 AKCINTDGSYKCLCLPGYVPSDKPNYCTP 1382
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
Query: 17 WFITTAATDTSEARWCSECH-----SNATCTEDEAVTTCTCQEGFTGDG--LTCVDLDEC 69
+FI ++ E EC N C + TC C +G+ D +TCVD++EC
Sbjct: 1282 YFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNEC 1341
Query: 70 -AIPGAHNCSANSSCVNTPGSFSCVCPEGF 98
+ + N+ C+NT GS+ C+C G+
Sbjct: 1342 DELNNRMSLCKNAKCINTDGSYKCLCLPGY 1371
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 13/99 (13%)
Query: 63 CVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGL-GCTDVDECAEPGLSHCH 121
C D++EC + G N C+NT GS+ C C GF P C C+
Sbjct: 298 CQDINECQLQGV---CPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCY 354
Query: 122 ALAT----CVNVVGSY----LCVCPAGYRGDGWHCECSP 152
L + C++ + + LC C G + G HCE P
Sbjct: 355 RLVSSGRQCMHPLSVHLTKQLCCCSVG-KAWGPHCEKCP 392
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 34 ECHSNATCTEDEAVTTCTCQEGFTGDG--LTCVDLDECAIPGAHNCSANSSCVNTPGSFS 91
E N C C C++G D L C D+DEC P + + CVNT GS++
Sbjct: 1109 EICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSS---CIDGQCVNTEGSYN 1165
Query: 92 CVC 94
C C
Sbjct: 1166 CFC 1168
Score = 38.9 bits (89), Expect = 0.015
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 11/92 (11%)
Query: 94 CPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPG 153
C G++ C D++EC G+ C+N +GSY C C G+ D C P
Sbjct: 286 CLPGYKRVNNTFCQDINECQLQGVC---PNGECLNTMGSYRCTCKIGFGPDPTFSSCVPD 342
Query: 154 ------SCGPGLDCVPEGDALVCADPCQAHRT 179
GP V G C P H T
Sbjct: 343 PPVISEEKGPCYRLVSSGRQ--CMHPLSVHLT 372
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 94.7 bits (234), Expect = 2e-19
Identities = 94/334 (28%), Positives = 130/334 (38%), Gaps = 58/334 (17%)
Query: 35 CHSNATCTEDEAVTTCTCQEGFT----GDGLTCVDLDECAIPGAHNCSANSSCVNTPGSF 90
C C +C C G+T G C D++EC PG CS C NT GS+
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGV--CSGGQ-CTNTEGSY 952
Query: 91 SCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCV-CPAGYRGDGWHC- 148
C C +G+ + C D++EC PG CVN GSY C+ C GYRG C
Sbjct: 953 HCECDQGYIMVRKGHCQDINECRHPGTCPD---GRCVNSPGSYTCLACEEGYRGQSGSCV 1009
Query: 149 ---EC-SPGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYR 204
EC +PG C G C + C+ C+ +GY +D +G +
Sbjct: 1010 DVNECLTPGVCAHG-KCTNLEGSFRCS--CE---------------QGYEVTSDEKGC-Q 1050
Query: 205 FVGQGGARMAETCVPVLRCNTAAPM---------WLN--GTHPSSDEGIVSRKACAHWSG 253
V + +R + C L NT W+N GT + C SG
Sbjct: 1051 DVDECASRAS--CPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCP--SG 1106
Query: 254 HCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRW 313
C S K C GGY L E + C DP S +C + +CK+ G +
Sbjct: 1107 VCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQS---SC----LGGECKNTVGSY 1158
Query: 314 HCQCKQDFNITDISLLEHRLECGANDMKVSLGKC 347
C C Q F + + ++ E EC + G+C
Sbjct: 1159 QCLCPQGFQLANGTVCEDVNECMGEEHCAPHGEC 1192
Score = 86.3 bits (212), Expect = 8e-17
Identities = 85/305 (27%), Positives = 117/305 (38%), Gaps = 85/305 (27%)
Query: 33 SECHSNATCTEDEAVT-----TC-TCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNT 86
+EC TC + V TC C+EG+ G +CVD++EC PG A+ C N
Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGV---CAHGKCTNL 1028
Query: 87 PGSFSCVCPEGFRL-SPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLC-VCPAGY--R 142
GSF C C +G+ + S GC DVDECA + C C+N GS+ C C GY
Sbjct: 1029 EGSFRCSCEQGYEVTSDEKGCQDVDECASR--ASCPT-GLCLNTEGSFACSACENGYWVN 1085
Query: 143 GDGWHCE----CS-PGSCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGEGYACDT 197
DG CE C+ PG C G+ C + C D CD
Sbjct: 1086 EDGTACEDLDECAFPGVCPSGV-CTNTAGSFSCKD----------------------CD- 1121
Query: 198 DLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSG-HCC 256
G YR + + ++C V C L G C + G + C
Sbjct: 1122 ---GGYR-----PSPLGDSCEDVDECEDPQSSCLGGE-------------CKNTVGSYQC 1160
Query: 257 LWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQ 316
L C G+ + N T C D + G E C+ +C +++G + C
Sbjct: 1161 L---------CPQGFQLANGTV--------CEDVNECMGE-EHCAPHGECLNSHGSFFCL 1202
Query: 317 CKQDF 321
C F
Sbjct: 1203 CAPGF 1207
Score = 85.1 bits (209), Expect = 2e-16
Identities = 63/232 (27%), Positives = 88/232 (37%), Gaps = 32/232 (13%)
Query: 21 TAATDTSEARWCSECHSNATCTEDEAVTTCT-CQEGFTGDGL--TCVDLDECAIPGAHNC 77
TA D E + C S CT +C C G+ L +C D+DEC P +
Sbjct: 1089 TACEDLDECAFPGVCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDP--QSS 1145
Query: 78 SANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
C NT GS+ C+CP+GF+L+ G C DV+EC G HC C+N GS+ C+C
Sbjct: 1146 CLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECM--GEEHCAPHGECLNSHGSFFCLC 1203
Query: 138 PAGYRGD-------------------GWHCECSPGS----CGPGLDCVPEGDALVCADPC 174
G+ G HC + GS C G PE V D C
Sbjct: 1204 APGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDEC 1263
Query: 175 QAH-RTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNT 225
+ + + W+ Y C + + G + C C +
Sbjct: 1264 EDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGS 1315
Score = 80.9 bits (198), Expect = 3e-15
Identities = 52/123 (42%), Positives = 66/123 (53%), Gaps = 16/123 (13%)
Query: 52 CQEGF----TGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSP-GLGC 106
CQ GF GD C+D+DECA C ++ C NT GSF C+C +GF +SP G C
Sbjct: 1289 CQPGFHMAPNGD---CIDIDECA--NDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDC 1343
Query: 107 TDVDECAEPGLSHCHALATCVNVVGSYLCVCPAG---YRGDGWHCECSPGSCGPGLDCVP 163
DV+EC E L+ C A A C NV GS+LC+C + Y HC G+ G + P
Sbjct: 1344 VDVNEC-ELMLAVCGA-ALCENVEGSFLCLCASDLEEYDAQEGHCR-PRGAGGQSMSEAP 1400
Query: 164 EGD 166
GD
Sbjct: 1401 TGD 1403
Score = 51.2 bits (121), Expect = 3e-06
Identities = 48/173 (27%), Positives = 63/173 (36%), Gaps = 26/173 (15%)
Query: 26 TSEARWCSECHSNATCTEDEAVTTCTCQEG---------FTGDGLTCVDLDECAIPGAHN 76
T A W C + +ED A + C G +T D DEC I G
Sbjct: 1439 TQGASWGDAC--DLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGL 1496
Query: 77 CSANSSCVNTPGSFSCVCPEGFRLSPG-LGCTDVDECAEPGLSHCHALATCVNVVGSYLC 135
C N C+NT + C+C GF C D DEC + + CVN GS+ C
Sbjct: 1497 CP-NGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACEN----GECVNTEGSFHC 1551
Query: 136 VCPAGYRGDGWHCECSPGSCG----PGLD-----CVPEGDALVCADPCQAHRT 179
C D C + P D C + VC++P + HRT
Sbjct: 1552 FCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRT 1604
Score = 49.7 bits (117), Expect = 8e-06
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 60 GLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPG-LGCTDVDECAE---P 115
G + +EC G N N CV ++C C EGF+L + C DV+EC + P
Sbjct: 1728 GFEGLQAEEC---GILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGP 1784
Query: 116 GLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECS 151
+ H C N GSY C C GY + C+
Sbjct: 1785 AVLCVHGY--CENTEGSYRCHCSPGYVAEAGPPHCT 1818
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/187 (24%), Positives = 68/187 (36%), Gaps = 15/187 (8%)
Query: 25 DTSEARWCSECHSNATCTEDEAVTTCTCQEGF--TGDGLTCVDLDECAIPGAHNCSANSS 82
D E + C S+ C + C C +GF + G CVD++EC + A C A +
Sbjct: 1303 DIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLA-VCGA-AL 1360
Query: 83 CVNTPGSFSCVC---------PEGFRLSPGLGCTDVDECAEPGLSHCHALATCVN-VVGS 132
C N GSF C+C EG G G + E + C + G
Sbjct: 1361 CENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGH 1420
Query: 133 YLCVCPAGYRGDGWHCECSPG-SCGPGLDCVPEGDALVCADPCQAHRTLDEYWRSTEYGE 191
C G C C+ G S G D P D+ ++ C + + + +G+
Sbjct: 1421 APCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQ 1480
Query: 192 GYACDTD 198
D D
Sbjct: 1481 TMYTDAD 1487
Score = 44.7 bits (104), Expect = 3e-04
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 16/88 (18%)
Query: 38 NATCTEDEAVTTCTCQEGFTGDG--LTCVDLDEC-AIPGAHNCSANSSCVNTPGSFSCVC 94
N C TC C EGF D + CVD++EC + G + C NT GS+ C C
Sbjct: 1745 NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHC 1804
Query: 95 PEGFRLSPGLGCTDVDECAEPGLSHCHA 122
G+ AE G HC A
Sbjct: 1805 SPGY-------------VAEAGPPHCTA 1819
Score = 43.1 bits (100), Expect = 8e-04
Identities = 46/158 (29%), Positives = 57/158 (36%), Gaps = 26/158 (16%)
Query: 46 AVTTCTCQEGFTGD-------GLTCVDLDECAIPGAHNCSANSSCVNTPGS-FSCVCPEG 97
A T C G G G + C GA A C + + FS +CP G
Sbjct: 1407 APTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSG 1466
Query: 98 FRLSPGLGC--------TDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWH-- 147
P G TD DEC G C C+N V Y+C+C G+ D H
Sbjct: 1467 KGYIPVEGAWTFGQTMYTDADECVIFGPGLCPN-GRCLNTVPGYVCLCNPGFHYDASHKK 1525
Query: 148 C----ECSPGSCGPGLDCVPEGDALVCADPCQAHRTLD 181
C EC +C G +CV + C C TLD
Sbjct: 1526 CEDHDECQDLACENG-ECVNTEGSFHCF--CSPPLTLD 1560
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 12/112 (10%)
Query: 52 CQEGFTGDGLT-CVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLG-CTDV 109
C +G+ LT C D++EC G ++ CVNT GS+ C C G L P C
Sbjct: 608 CPQGYKRLNLTHCQDINECLTLGL---CKDAECVNTRGSYLCTCRPGLMLDPSRSRCV-- 662
Query: 110 DECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDC 161
++ +S L C +G C P R C CS G +C
Sbjct: 663 ---SDKAISMLQGL--CYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSEC 709
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,308,509
Number of Sequences: 37866
Number of extensions: 1381949
Number of successful extensions: 6606
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 152
Number of HSP's successfully gapped in prelim test: 139
Number of HSP's that attempted gapping in prelim test: 2690
Number of HSP's gapped (non-prelim): 1656
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.