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Search of human proteins with 56090620
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56090620 NFKB activating protein-like [Homo sapiens]
(402 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56090620 NFKB activating protein-like [Homo sapiens] 816 0.0
gi|168229156 NFKB activating protein [Homo sapiens] 452 e-127
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 68 2e-11
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 66 5e-11
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] 66 5e-11
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens] 65 8e-11
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens] 65 8e-11
gi|52426743 cisplatin resistance-associated overexpressed protei... 65 8e-11
gi|19923485 cisplatin resistance-associated overexpressed protei... 65 8e-11
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 65 1e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 65 1e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 65 1e-10
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 64 2e-10
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 64 2e-10
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 62 7e-10
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 62 7e-10
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 62 1e-09
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 62 1e-09
gi|27883882 P18SRP protein [Homo sapiens] 61 2e-09
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 61 2e-09
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 61 2e-09
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 60 3e-09
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 60 3e-09
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 59 8e-09
gi|21361576 zinc finger, CCHC domain containing 17 [Homo sapiens] 59 8e-09
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 59 1e-08
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 57 2e-08
gi|50962882 G patch domain containing 8 [Homo sapiens] 57 4e-08
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 56 5e-08
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 56 7e-08
>gi|56090620 NFKB activating protein-like [Homo sapiens]
Length = 402
Score = 816 bits (2108), Expect = 0.0
Identities = 402/402 (100%), Positives = 402/402 (100%)
Query: 1 MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDV 60
MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDV
Sbjct: 1 MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDV 60
Query: 61 GALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQR 120
GALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQR
Sbjct: 61 GALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQR 120
Query: 121 RLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKT 180
RLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKT
Sbjct: 121 RLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKT 180
Query: 181 SRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKK 240
SRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKK
Sbjct: 181 SRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKK 240
Query: 241 NKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHAL 300
NKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHAL
Sbjct: 241 NKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHAL 300
Query: 301 LPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVRLRKENQI 360
LPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVRLRKENQI
Sbjct: 301 LPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVRLRKENQI 360
Query: 361 YSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK 402
YSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK
Sbjct: 361 YSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK 402
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 452 bits (1164), Expect = e-127
Identities = 266/420 (63%), Positives = 308/420 (73%), Gaps = 23/420 (5%)
Query: 1 MPPVSRS-SYSEDIVGSRRRRRSSSGSPP------SPQSRCSSWDGCSRSHSRGREGLRP 53
M PVS S S + GS RRRSSS SP SP+ R S CSRS R GL
Sbjct: 1 MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRN--GLTH 58
Query: 54 PWSELDVGALYPF----SRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAE 109
L G+ SRS SR R R FAS+ S+ Y G + + S
Sbjct: 59 QLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLL 118
Query: 110 DYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSD 169
D E+EES RQ+RL ERERIGELGAPEVWG SPK P+ DSDEHTPVEDEE +KS++S
Sbjct: 119 DKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEP---KKSTTSA 175
Query: 170 SNSEEHRKKKTSRS--RNKKKRKNKSSKRKHRKYS-DSDSNSESDTNSDSDDDKKRVK-A 225
S SEE +KKK+SRS R+KK+RK KSSKRKH+KYS DSDS+S+S+T+S +D+K+R K A
Sbjct: 176 STSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKA 235
Query: 226 KKKKKKKKHKTKK---KKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEA 282
KKK+KKKKH++KK K++KK++KESSDSS K+S+E+ E W ++ + DLIGPEA
Sbjct: 236 KKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEA 295
Query: 283 PIIHTSQDEKPLKYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMS 342
P TSQD+KPL YGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEI SFECSGYVMS
Sbjct: 296 PKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMS 355
Query: 343 GSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK 402
GSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRE+KILASFREMV++KTK KDDK
Sbjct: 356 GSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK 415
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 67.8 bits (164), Expect = 2e-11
Identities = 35/86 (40%), Positives = 55/86 (63%), Gaps = 3/86 (3%)
Query: 181 SRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHK---TK 237
S+ + ++K+++KSS SDSDS+S+S ++SDS D + + K KK+KKKH+ K
Sbjct: 181 SKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRK 240
Query: 238 KKKNKKTKKESSDSSCKDSEEDLSEA 263
KK KK +K+S S+ +SE + EA
Sbjct: 241 HKKEKKKRKKSKKSASSESEAENLEA 266
Score = 50.4 bits (119), Expect = 3e-06
Identities = 60/272 (22%), Positives = 107/272 (39%), Gaps = 44/272 (16%)
Query: 16 SRRRRRSSSGSPP-----SPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFSRSG 70
+R R R +PP S Q R + RG R P SRS
Sbjct: 301 NRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTP------------SRSR 348
Query: 71 SRGRL------PRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKE 124
SR R P +R + SG R+ + +E + E+ ++R++ +
Sbjct: 349 SRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITD 408
Query: 125 RERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDS--NSEEHRKKKTSR 182
+ E P+ K + + +E + S D N + R K SR
Sbjct: 409 HRNVSE-------SPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461
Query: 183 SRNKKKRKNKSSKRKHR-----------KYSDSDSNSESDTNSDS-DDDKKRVKAKKKKK 230
S++K+K K+K KH K D ++ E + SDS D++R ++K+K K
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK 521
Query: 231 KKKHKTKKKKNKKTKKESSDSSCKDSEEDLSE 262
+ + K+ + + K+K++ + + E D+++
Sbjct: 522 QLESKSNEHDHSKSKEKDRRAQSRSRECDITK 553
Score = 50.4 bits (119), Expect = 3e-06
Identities = 53/198 (26%), Positives = 82/198 (41%), Gaps = 13/198 (6%)
Query: 67 SRSGSRGRLPRFRNYAFASSWSTSYSGYR---YHRHCYAEERQSAEDYEKEESHRQRRLK 123
SRS R R R R + S S Y YR Y R + R+ + S +RR +
Sbjct: 566 SRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRR 625
Query: 124 ERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRS 183
R E + K+ +S E+ E S S D NS ++ S
Sbjct: 626 RDSRSSEREESQSRNKD-KYRNQESKSSHRKENSESEKRMYSKSRDHNS-------SNNS 677
Query: 184 RNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKK 243
R KK +++S K K S D+ +S + +D+K R +K+ +K K + ++K
Sbjct: 678 REKKADRDQSPFSKI-KQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEK 736
Query: 244 TKKESSDSSCKDSEEDLS 261
KK +SS ++ED S
Sbjct: 737 NKKFDHESS-PGTDEDKS 753
Score = 46.6 bits (109), Expect = 4e-05
Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 15/161 (9%)
Query: 121 RLKERERIGELGAPEVWGPSPKFPQ---LDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRK 177
R + R+R P W + Q + S E D+ E+ K + + RK
Sbjct: 346 RSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK 405
Query: 178 ----KKTSRSRNKKKRKNKSSKRKHRKYSDSDSNS-ESDTNSDSDDDKKRVKAKKKKKKK 232
+ S S N+K K K K D SNS E D +S+ D K KK+ K
Sbjct: 406 ITDHRNVSESPNRKNEKEK-------KVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKS 458
Query: 233 KHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVAD 273
K ++K K+ K+K+ S + + + S + + NV +
Sbjct: 459 KSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKE 499
Score = 44.7 bits (104), Expect = 2e-04
Identities = 65/247 (26%), Positives = 93/247 (37%), Gaps = 75/247 (30%)
Query: 68 RSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERER 127
RS SR R R R+ S S YHR Y ++E R+ R + RER
Sbjct: 565 RSRSRDRSRRVRSRTHDRDRSRSKE---YHR------------YREQEYRRRGRSRSRER 609
Query: 128 IGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKK 187
TP ++ DS S E ++ S+SRNK
Sbjct: 610 -----------------------RTP-PGRSRSKDRRRRRRDSRSSE---REESQSRNKD 642
Query: 188 KRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKN------ 241
K +N+ SK HRK NSES+ KR+ +K + + +++KK
Sbjct: 643 KYRNQESKSSHRK-----ENSESE---------KRMYSKSRDHNSSNNSREKKADRDQSP 688
Query: 242 -KKTKKESSDSSCKDS----EEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKY 296
K K+ S D+ K S +ED + +E+ N G E +H EK K+
Sbjct: 689 FSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSK----GQENDHVH----EKNKKF 740
Query: 297 GHALLPG 303
H PG
Sbjct: 741 DHESSPG 747
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 14/114 (12%)
Query: 148 SDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNK---SSKRKHRKYSDS 204
S + + + + SSSDS+ E ++ S+ R KK RKN ++K RK S
Sbjct: 194 SSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKK 253
Query: 205 DSNSESDTNSDSDDDKKRVKAKK-----------KKKKKKHKTKKKKNKKTKKE 247
++SES+ + + V+ ++ +K K K++KN++ ++E
Sbjct: 254 SASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERE 307
Score = 42.7 bits (99), Expect = 6e-04
Identities = 35/194 (18%), Positives = 88/194 (45%), Gaps = 3/194 (1%)
Query: 77 RFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEV 136
R ++ + + S S S R +H EE++ K H + KE++ + E
Sbjct: 455 RAKSKSRSKSKEKSKSKERDSKHNRNEEKRM-RSRSKGRDHENVKEKEKQSDSKGKDQER 513
Query: 137 WGPSPKFPQLDS--DEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSS 194
K QL+S +EH + +E+ +S S + + + + SR+R + + +++S
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR 573
Query: 195 KRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCK 254
+ + R + S S+ + ++R +++ ++++ + K+++ ++ S SS +
Sbjct: 574 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSER 633
Query: 255 DSEEDLSEATWMEQ 268
+ + ++ + Q
Sbjct: 634 EESQSRNKDKYRNQ 647
Score = 39.7 bits (91), Expect = 0.005
Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 21/103 (20%)
Query: 154 VEDEEEVTHQKSSSS-------DSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDS 206
V+ EE+ H+ SSSS DS+S+ +S S + + K+K K+KHRK S
Sbjct: 183 VKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS---- 238
Query: 207 NSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESS 249
+ KKR KK KK + +N + + +S+
Sbjct: 239 ------RKHKKEKKKR----KKSKKSASSESEAENLEAQPQST 271
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 66.2 bits (160), Expect = 5e-11
Identities = 60/216 (27%), Positives = 92/216 (42%), Gaps = 15/216 (6%)
Query: 67 SRSGSRG---RLPRFRNYAFASSWSTSYSGYRYHRHCYAEE-----RQSAEDYEKEESHR 118
SRS RG R R R + S S G R R E+ R+ DY+KE +
Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNE 377
Query: 119 QRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKK 178
+ + +ER R K + D D+ +D+ + +K S S S E + +
Sbjct: 378 REKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSR-SRSRERKHR 436
Query: 179 KTSRSRNKKKR-----KNKSSKRKHRKYSDSDSNSESDTNSDSDD-DKKRVKAKKKKKKK 232
SRSRN KR K KSSK K+ S+ S S + +D +K + + K+K
Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEK 496
Query: 233 KHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQ 268
K + K + K++ SDS + + D + +EQ
Sbjct: 497 SRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQ 532
Score = 55.5 bits (132), Expect = 9e-08
Identities = 42/203 (20%), Positives = 84/203 (41%), Gaps = 12/203 (5%)
Query: 103 EERQSAEDYEKEESHRQRRLKE--------RERIGELGAPEVWGPSPKFPQLDSDEHTPV 154
+ERQ E KE +RR + R R E K + D D
Sbjct: 299 KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKR-KNKSSKRKHRKYSDSDSNSESDTN 213
E+E + + +E ++++ SR R+K++R + + ++KH++ D D D
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE--DKDDRRHRDDK 416
Query: 214 SDSDDDKKRVKAKKKKKKKKHKTKKKK-NKKTKKESSDSSCKDSEEDLSEATWMEQPNVA 272
DS +KK +++ +++K + +++ + K+++ S + S K E ++ +
Sbjct: 417 RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQ 476
Query: 273 DTMDLIGPEAPIIHTSQDEKPLK 295
D + H+ EK K
Sbjct: 477 GRTDSVEKSKKREHSPSKEKSRK 499
Score = 52.0 bits (123), Expect = 9e-07
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 7/233 (3%)
Query: 6 RSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYP 65
R S S D RRR RS +SR D R R +E R + D
Sbjct: 316 RRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERG 375
Query: 66 FSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKER 125
R R R R R+ S ++ + R D +KE+ H + R +ER
Sbjct: 376 NEREKERER-SRERSKEQRSRGEVEEKKHKEDKDD-RRHRDDKRDSKKEKKHSRSRSRER 433
Query: 126 ERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRN 185
+ + S + S +H E+ +S S + KK S +
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493
Query: 186 KKK-RKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTK 237
K+K RK SK + K SDS +SD + D ++ +++ ++K+HK K
Sbjct: 494 KEKSRKRSRSKERSHKRDHSDSKDQSDKH----DRRRSQSIEQESQEKQHKNK 542
Score = 38.5 bits (88), Expect = 0.011
Identities = 52/249 (20%), Positives = 99/249 (39%), Gaps = 22/249 (8%)
Query: 157 EEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKK---RKNKSSKRKHRKYSDSDSNSESDTN 213
+ E+ +K + R+K+ RSR+ + R+ S+ +HR S S S
Sbjct: 292 DRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHR----SRSRSRDRKG 347
Query: 214 SDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVAD 273
D D++R K ++ +++ K++ + +KE + S + S+E S E+ + D
Sbjct: 348 DRRDRDREREKENERGRRRDRDYDKERGNEREKE-RERSRERSKEQRSRGEVEEKKHKED 406
Query: 274 TMDLIGPEAPIIHTSQDEKPLKYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGS 333
D + S+ EK + + + + AGKR R + + + S
Sbjct: 407 KDDRRHRDDK--RDSKKEKKHSRSRS-RERKHRSRSRSRNAGKRSRSRSKEKSSKHKNES 463
Query: 334 FECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRESKILASFREMVH 393
E S R ++V K+ + + EK S ++E KR+ H
Sbjct: 464 KEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRD-----------H 512
Query: 394 KKTKEKDDK 402
+K++ DK
Sbjct: 513 SDSKDQSDK 521
Score = 30.4 bits (67), Expect = 3.0
Identities = 16/97 (16%), Positives = 49/97 (50%), Gaps = 10/97 (10%)
Query: 173 EEHRKKKTSRS--RNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKK 230
+ H +++ SRS R+ R++ R + + +S D + + +++R++ + K++
Sbjct: 252 DRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKER 311
Query: 231 KKKHK--------TKKKKNKKTKKESSDSSCKDSEED 259
+K+ + ++++++ ++ S S +D + D
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348
>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
Length = 292
Score = 66.2 bits (160), Expect = 5e-11
Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 8/140 (5%)
Query: 130 ELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS-----SDSNSEEHRKKKTSRSR 184
E P+ WG S + +L +E D++++T+ K +S S S +H+K K S +
Sbjct: 101 EANMPDRWGHSG-YKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK 159
Query: 185 NKKKRKNKSSKRKHRKYSD--SDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNK 242
+KKR +K K+ ++ +D +DS+SE + + +K + K+KKK + K+ KK
Sbjct: 160 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 219
Query: 243 KTKKESSDSSCKDSEEDLSE 262
+ ES+ S DS SE
Sbjct: 220 FLEAESNTSHSDDSASSSSE 239
Score = 50.8 bits (120), Expect = 2e-06
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 16/183 (8%)
Query: 93 GYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHT 152
G+ ++ Y EE ++ D + + ++ + + E + S K Q
Sbjct: 109 GHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKK 168
Query: 153 PVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRK---YSDSDSN-- 207
+ ++E T + SS SEE T + + KRK KS K+ +K + +++SN
Sbjct: 169 QKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTS 228
Query: 208 -SESDTNSDSDDDKKR--VKAKKKKKKKKHKT-------KKKKNKKTK-KESSDSSCKDS 256
S+ +S S++ ++R K K+KK++KK T +++ NK+T K ++D +S
Sbjct: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288
Query: 257 EED 259
ED
Sbjct: 289 SED 291
Score = 33.1 bits (74), Expect = 0.46
Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 22/123 (17%)
Query: 101 YAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160
++EE ++ + ++ H++ K++ R L P ++ L+++ +T D+
Sbjct: 187 FSEETGASGTRKGKQPHKR---KKKSRKKSLKKPALF--------LEAESNTSHSDDS-- 233
Query: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKR-----KNKSSKRKHRKYSDSDSNSESDTNSD 215
+SSS SEE KKT R + +KK N+ +R +++ + + E S
Sbjct: 234 ----ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 289
Query: 216 SDD 218
DD
Sbjct: 290 EDD 292
Score = 32.0 bits (71), Expect = 1.0
Identities = 32/143 (22%), Positives = 55/143 (38%), Gaps = 7/143 (4%)
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214
E + K+ S + ++ K K+ + N + H Y + E +T+S
Sbjct: 67 ESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPE-EFETDS 125
Query: 215 DSDDDKKRVKAKKKKKKKKHKTKK--KKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVA 272
D D K + K H+++K K K KK+ S K ++ EAT + A
Sbjct: 126 DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI----TA 181
Query: 273 DTMDLIGPEAPIIHTSQDEKPLK 295
D+ E T + ++P K
Sbjct: 182 DSSSEFSEETGASGTRKGKQPHK 204
>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 65.5 bits (158), Expect = 8e-11
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 130 ELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS-----SDSNSEEHRKKKTSRSR 184
E P+ WG S + T D++++T+ K +S S S +H+K K S +
Sbjct: 101 EANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK 160
Query: 185 NKKKRKNKSSKRKHRKYSD--SDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNK 242
+KKR +K K+ ++ +D +DS+SE + + +K + K+KKK + K+ KK
Sbjct: 161 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 220
Query: 243 KTKKESSDSSCKDSEEDLSE 262
+ ES+ S DS SE
Sbjct: 221 FLEAESNTSHSDDSASSSSE 240
Score = 48.9 bits (115), Expect = 8e-06
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 28/163 (17%)
Query: 113 KEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNS 172
K +H R+ K+ ++ S K Q + ++E T + SS S
Sbjct: 142 KSSTHESRKHKKSKK------------SHKKKQKKRSHKKQKKSKKEATDITADSSSEFS 189
Query: 173 EEHRKKKTSRSRNKKKRKNKSSKRKHRK---YSDSDSN---SESDTNSDSDDDKKR--VK 224
EE T + + KRK KS K+ +K + +++SN S+ +S S++ ++R K
Sbjct: 190 EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKK 249
Query: 225 AKKKKKKKKHKT-------KKKKNKKTK-KESSDSSCKDSEED 259
K+KK++KK T +++ NK+T K ++D +S ED
Sbjct: 250 TKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
Score = 33.1 bits (74), Expect = 0.46
Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 22/123 (17%)
Query: 101 YAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160
++EE ++ + ++ H++ K++ R L P ++ L+++ +T D+
Sbjct: 188 FSEETGASGTRKGKQPHKR---KKKSRKKSLKKPALF--------LEAESNTSHSDDS-- 234
Query: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKR-----KNKSSKRKHRKYSDSDSNSESDTNSD 215
+SSS SEE KKT R + +KK N+ +R +++ + + E S
Sbjct: 235 ----ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
Query: 216 SDD 218
DD
Sbjct: 291 EDD 293
Score = 32.7 bits (73), Expect = 0.60
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 18/127 (14%)
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSD---SDSNSESD 211
E + K+ S + ++ K K+ + N + H Y + + ++S
Sbjct: 67 ESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSS 126
Query: 212 TNSDSDDDKK---RVKA---KKKKKKKKHKTKK--------KKNKKTKKESSDSSCKDSE 257
D + KK +VK+ + +K KK K+ K KK KK+KKE++D + DS
Sbjct: 127 DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA-DSS 185
Query: 258 EDLSEAT 264
+ SE T
Sbjct: 186 SEFSEET 192
>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 65.5 bits (158), Expect = 8e-11
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 130 ELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS-----SDSNSEEHRKKKTSRSR 184
E P+ WG S + T D++++T+ K +S S S +H+K K S +
Sbjct: 101 EANMPDRWGHSGYKELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK 160
Query: 185 NKKKRKNKSSKRKHRKYSD--SDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNK 242
+KKR +K K+ ++ +D +DS+SE + + +K + K+KKK + K+ KK
Sbjct: 161 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 220
Query: 243 KTKKESSDSSCKDSEEDLSE 262
+ ES+ S DS SE
Sbjct: 221 FLEAESNTSHSDDSASSSSE 240
Score = 48.9 bits (115), Expect = 8e-06
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 28/163 (17%)
Query: 113 KEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNS 172
K +H R+ K+ ++ S K Q + ++E T + SS S
Sbjct: 142 KSSTHESRKHKKSKK------------SHKKKQKKRSHKKQKKSKKEATDITADSSSEFS 189
Query: 173 EEHRKKKTSRSRNKKKRKNKSSKRKHRK---YSDSDSN---SESDTNSDSDDDKKR--VK 224
EE T + + KRK KS K+ +K + +++SN S+ +S S++ ++R K
Sbjct: 190 EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKK 249
Query: 225 AKKKKKKKKHKT-------KKKKNKKTK-KESSDSSCKDSEED 259
K+KK++KK T +++ NK+T K ++D +S ED
Sbjct: 250 TKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 292
Score = 33.1 bits (74), Expect = 0.46
Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 22/123 (17%)
Query: 101 YAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160
++EE ++ + ++ H++ K++ R L P ++ L+++ +T D+
Sbjct: 188 FSEETGASGTRKGKQPHKR---KKKSRKKSLKKPALF--------LEAESNTSHSDDS-- 234
Query: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKR-----KNKSSKRKHRKYSDSDSNSESDTNSD 215
+SSS SEE KKT R + +KK N+ +R +++ + + E S
Sbjct: 235 ----ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 290
Query: 216 SDD 218
DD
Sbjct: 291 EDD 293
Score = 32.7 bits (73), Expect = 0.60
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 18/127 (14%)
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSD---SDSNSESD 211
E + K+ S + ++ K K+ + N + H Y + + ++S
Sbjct: 67 ESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSS 126
Query: 212 TNSDSDDDKK---RVKA---KKKKKKKKHKTKK--------KKNKKTKKESSDSSCKDSE 257
D + KK +VK+ + +K KK K+ K KK KK+KKE++D + DS
Sbjct: 127 DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA-DSS 185
Query: 258 EDLSEAT 264
+ SE T
Sbjct: 186 SEFSEET 192
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 65.5 bits (158), Expect = 8e-11
Identities = 39/157 (24%), Positives = 69/157 (43%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
EER+ + E+EE R+RR +E ER E + S + H
Sbjct: 255 EEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDH 314
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
++S S + R ++ SRS ++ +RK++S R R+ D S + D ++ R
Sbjct: 315 KRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR 374
Query: 223 VKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEED 259
+K+K+ K K+ +K+S D++ + E D
Sbjct: 375 KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
Score = 56.6 bits (135), Expect = 4e-08
Identities = 46/176 (26%), Positives = 81/176 (46%), Gaps = 8/176 (4%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
EE E +KE+ R+ R KERER E + + + + + + +
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSR 298
Query: 163 QKSSSSD---SNSEEH---RKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDS 216
S +SD S S +H R ++ RSR++ +R+++S R RK+ + + D
Sbjct: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 217 DDDKKRVKAKKKKKKKKHKTKKKKNKKTKKES--SDSSCKDSEEDLSEATWMEQPN 270
K R K++ +++ +K K K+K+ KK S S S K SE+ +E+ + N
Sbjct: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKN 414
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/119 (20%), Positives = 48/119 (40%), Gaps = 3/119 (2%)
Query: 108 AEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS 167
+ D+++ S +RR + R+R K D + + +S S
Sbjct: 311 SRDHKRSRSRERRRSRSRDRRRSRSHDR---SERKHRSRSRDRRRSKSRDRKSYKHRSKS 367
Query: 168 SDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAK 226
D + K+K R + KK KS R+ + + + ESDT ++ + + +K++
Sbjct: 368 RDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
Score = 33.5 bits (75), Expect = 0.35
Identities = 18/105 (17%), Positives = 55/105 (52%), Gaps = 18/105 (17%)
Query: 154 VEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTN 213
VE+ +E +++ D + E +K+K R +K+R+ + +R+ ++ +
Sbjct: 227 VEELKEKLRKRTEEPDRD-ERLKKEKQEREEREKEREREREERERKRRRE---------- 275
Query: 214 SDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258
++++++ +A+ ++++K+ +++ + + +T SD C S +
Sbjct: 276 ---EEEREKERARDRERRKRSRSRSRHSSRT----SDRRCSRSRD 313
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 65.5 bits (158), Expect = 8e-11
Identities = 39/157 (24%), Positives = 69/157 (43%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
EER+ + E+EE R+RR +E ER E + S + H
Sbjct: 255 EEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDH 314
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
++S S + R ++ SRS ++ +RK++S R R+ D S + D ++ R
Sbjct: 315 KRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR 374
Query: 223 VKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEED 259
+K+K+ K K+ +K+S D++ + E D
Sbjct: 375 KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
Score = 56.6 bits (135), Expect = 4e-08
Identities = 46/176 (26%), Positives = 81/176 (46%), Gaps = 8/176 (4%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
EE E +KE+ R+ R KERER E + + + + + + +
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSR 298
Query: 163 QKSSSSD---SNSEEH---RKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDS 216
S +SD S S +H R ++ RSR++ +R+++S R RK+ + + D
Sbjct: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 217 DDDKKRVKAKKKKKKKKHKTKKKKNKKTKKES--SDSSCKDSEEDLSEATWMEQPN 270
K R K++ +++ +K K K+K+ KK S S S K SE+ +E+ + N
Sbjct: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKN 414
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/119 (20%), Positives = 48/119 (40%), Gaps = 3/119 (2%)
Query: 108 AEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS 167
+ D+++ S +RR + R+R K D + + +S S
Sbjct: 311 SRDHKRSRSRERRRSRSRDRRRSRSHDR---SERKHRSRSRDRRRSKSRDRKSYKHRSKS 367
Query: 168 SDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAK 226
D + K+K R + KK KS R+ + + + ESDT ++ + + +K++
Sbjct: 368 RDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
Score = 33.5 bits (75), Expect = 0.35
Identities = 18/105 (17%), Positives = 55/105 (52%), Gaps = 18/105 (17%)
Query: 154 VEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTN 213
VE+ +E +++ D + E +K+K R +K+R+ + +R+ ++ +
Sbjct: 227 VEELKEKLRKRTEEPDRD-ERLKKEKQEREEREKEREREREERERKRRRE---------- 275
Query: 214 SDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258
++++++ +A+ ++++K+ +++ + + +T SD C S +
Sbjct: 276 ---EEEREKERARDRERRKRSRSRSRHSSRT----SDRRCSRSRD 313
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 64.7 bits (156), Expect = 1e-10
Identities = 75/275 (27%), Positives = 103/275 (37%), Gaps = 44/275 (16%)
Query: 25 GSPPSPQSRCSSWDGCSRSHSRGREGLRPPW-----SELDVG----ALYPFSRSGSRGRL 75
G SP R S CS HSR R G+ W +E + G YP R R
Sbjct: 1003 GDRLSPGER-RSLGRCSHHHSRHRSGVELDWVRHHYTEGERGWGREKFYPDRPRWDRCRY 1061
Query: 76 PRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGE--LGA 133
R +A+ + G R H ER + R +ER R GA
Sbjct: 1062 YHDRYALYAARDWKPFHGGREHERAGLHERPHKDHNRGRRGCEPARERERHRPSSPRAGA 1121
Query: 134 PEVWGPSPKFPQLDSDEHTPV------------EDEEEVTHQKSSSSDSNSEEHRKKKTS 181
P P P + D V E E + ++ S NS+ H +KK
Sbjct: 1122 PHALAPHPD--RFSHDRTALVAGDNCNLSDRFHEHENGKSRKRRHDSVENSDSHVEKKAR 1179
Query: 182 RSRNK------KKRKNKSSKRKHR---KYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKK 232
RS K K +K+K SK+K + K+ D DS + D++ + + KKKKKK
Sbjct: 1180 RSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDSRHQQDSDLSAACSDADLHRHKKKKKK 1239
Query: 233 KHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWME 267
K + +K S+ KDSE L T +E
Sbjct: 1240 KKRHSRK---------SEDFVKDSELHLPRVTSLE 1265
Score = 32.0 bits (71), Expect = 1.0
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 126 ERIGELGAPEVWGPSPKFPQLDS-----DEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKT 180
ER+ + AP+ GPSP ++ S H E + + + S S +E HR ++
Sbjct: 922 ERVEDAAAPKAPGPSPAKEKIGSLRKVDRGHYRSRRERSSSGEPARESRSKTEGHRHRRR 981
Query: 181 SRSRNKKKRKNKSSKRKHRKYSDSDSNSE 209
++ R+++ + H + D S E
Sbjct: 982 RTCPRERDRQDRHAPEHHPGHGDRLSPGE 1010
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 64.7 bits (156), Expect = 1e-10
Identities = 56/253 (22%), Positives = 106/253 (41%), Gaps = 26/253 (10%)
Query: 1 MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSW--DGCSRSHSRGREGLRPPWSEL 58
M P + + E+++ R +S + P+S S+ G SRSH+R +
Sbjct: 266 MTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK---------- 315
Query: 59 DVGALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHR 118
SRS S+ R R+ + S S + S R + R+S ++K R
Sbjct: 316 --------SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK-----DRRRSKSPHKKRSKSR 362
Query: 119 QRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKK 178
+RR K R R + K + ++ E E E +K N + +++
Sbjct: 363 ERR-KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 179 KTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKK 238
+ R ++K+K + + +++H K D + E D + + D+ + +K+KK KK +T
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 239 KKNKKTKKESSDS 251
+ +++ S S
Sbjct: 482 RSYNASRRSRSSS 494
Score = 58.2 bits (139), Expect = 1e-08
Identities = 62/262 (23%), Positives = 95/262 (36%), Gaps = 22/262 (8%)
Query: 16 SRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFSRSGSRGRL 75
SR RS S S SR RS S R R S+S R R
Sbjct: 308 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RK 366
Query: 76 PRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPE 135
R R+++ T +ER +D EKE + R KE+ER +
Sbjct: 367 SRSRSHSRDKRKDT-------REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK 419
Query: 136 VWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNK----KKRKN 191
+ + D+ E E E H+K + E+ ++K+ + R+K K++K+
Sbjct: 420 -----EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 474
Query: 192 KSSKRKHRKY-----SDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKK 246
K S+ R Y S S S S S R K+K + + + +NKK KK
Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 534
Query: 247 ESSDSSCKDSEEDLSEATWMEQ 268
+ + +T M +
Sbjct: 535 REKERDHISERRERERSTSMRK 556
Score = 55.1 bits (131), Expect = 1e-07
Identities = 48/198 (24%), Positives = 91/198 (45%), Gaps = 18/198 (9%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAP-EVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
ER+ + EKE + R KERE+ E + K + D D+ E ++E
Sbjct: 400 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Query: 163 QKSSSSDSNSEEHRKKKTS---RSRNKKKRKNKSSKRKHRKYSDSDSNSESDT------N 213
+K S + + + + KK+ RS N +R SS+ + R+ S S S S + +
Sbjct: 460 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 519
Query: 214 SDSDDDKKRVKAKKKKKKKK----HKTKKKKNKKTKKESSDSSCKDSEE----DLSEATW 265
S S + R K KK++K++ + +++++ +K S+D K+ E L E
Sbjct: 520 SRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 579
Query: 266 MEQPNVADTMDLIGPEAP 283
++P+ + + ++ +AP
Sbjct: 580 NKEPDSSVSKEVDDKDAP 597
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/221 (18%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 62 ALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRR 121
A+ P S + + R R++ + S S+S S R R+ ++ + SH + R
Sbjct: 292 AIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR---------RKRSQSKHRSRSHNRSR 342
Query: 122 LKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTS 181
++++R +P + + ++ S S S+S + RK
Sbjct: 343 SRQKDR--------------------RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE 382
Query: 182 RSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKN 241
+ + K++ K K +++ + + + E N D D ++++ + K K+K ++ + +K+
Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442
Query: 242 KKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEA 282
K KE K+ E + + +++ D P +
Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 483
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 64.7 bits (156), Expect = 1e-10
Identities = 56/253 (22%), Positives = 106/253 (41%), Gaps = 26/253 (10%)
Query: 1 MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSW--DGCSRSHSRGREGLRPPWSEL 58
M P + + E+++ R +S + P+S S+ G SRSH+R +
Sbjct: 150 MTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSK---------- 199
Query: 59 DVGALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHR 118
SRS S+ R R+ + S S + S R + R+S ++K R
Sbjct: 200 --------SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK-----DRRRSKSPHKKRSKSR 246
Query: 119 QRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKK 178
+RR K R R + K + ++ E E E +K N + +++
Sbjct: 247 ERR-KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 179 KTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKK 238
+ R ++K+K + + +++H K D + E D + + D+ + +K+KK KK +T
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 239 KKNKKTKKESSDS 251
+ +++ S S
Sbjct: 366 RSYNASRRSRSSS 378
Score = 58.2 bits (139), Expect = 1e-08
Identities = 62/262 (23%), Positives = 95/262 (36%), Gaps = 22/262 (8%)
Query: 16 SRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFSRSGSRGRL 75
SR RS S S SR RS S R R S+S R R
Sbjct: 192 SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RK 250
Query: 76 PRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPE 135
R R+++ T +ER +D EKE + R KE+ER +
Sbjct: 251 SRSRSHSRDKRKDT-------REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK 303
Query: 136 VWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNK----KKRKN 191
+ + D+ E E E H+K + E+ ++K+ + R+K K++K+
Sbjct: 304 -----EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 358
Query: 192 KSSKRKHRKY-----SDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKK 246
K S+ R Y S S S S S R K+K + + + +NKK KK
Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 418
Query: 247 ESSDSSCKDSEEDLSEATWMEQ 268
+ + +T M +
Sbjct: 419 REKERDHISERRERERSTSMRK 440
Score = 55.1 bits (131), Expect = 1e-07
Identities = 48/198 (24%), Positives = 91/198 (45%), Gaps = 18/198 (9%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAP-EVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
ER+ + EKE + R KERE+ E + K + D D+ E ++E
Sbjct: 284 EREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Query: 163 QKSSSSDSNSEEHRKKKTS---RSRNKKKRKNKSSKRKHRKYSDSDSNSESDT------N 213
+K S + + + + KK+ RS N +R SS+ + R+ S S S S + +
Sbjct: 344 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 403
Query: 214 SDSDDDKKRVKAKKKKKKKK----HKTKKKKNKKTKKESSDSSCKDSEE----DLSEATW 265
S S + R K KK++K++ + +++++ +K S+D K+ E L E
Sbjct: 404 SRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 463
Query: 266 MEQPNVADTMDLIGPEAP 283
++P+ + + ++ +AP
Sbjct: 464 NKEPDSSVSKEVDDKDAP 481
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/221 (18%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 62 ALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRR 121
A+ P S + + R R++ + S S+S S R R+ ++ + SH + R
Sbjct: 176 AIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR---------RKRSQSKHRSRSHNRSR 226
Query: 122 LKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTS 181
++++R +P + + ++ S S S+S + RK
Sbjct: 227 SRQKDR--------------------RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE 266
Query: 182 RSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKN 241
+ + K++ K K +++ + + + E N D D ++++ + K K+K ++ + +K+
Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326
Query: 242 KKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEA 282
K KE K+ E + + +++ D P +
Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 367
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 64.3 bits (155), Expect = 2e-10
Identities = 33/84 (39%), Positives = 53/84 (63%), Gaps = 5/84 (5%)
Query: 173 EEHRKK--KTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSD---DDKKRVKAKK 227
E+HR+K S S +KK+++ K K+K +YS S S+S ++S SD +DKK+ K +K
Sbjct: 64 EKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRK 123
Query: 228 KKKKKKHKTKKKKNKKTKKESSDS 251
KKK + HK+ + +T+ +S DS
Sbjct: 124 KKKNRSHKSSESSMSETESDSKDS 147
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/162 (30%), Positives = 73/162 (45%), Gaps = 21/162 (12%)
Query: 112 EKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV-----THQKSS 166
E RQR+ KE+++ G + DS++ + + +H+ S
Sbjct: 75 ESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSE 134
Query: 167 SSDSNSEEH-----RKKKTSRSRNKKKRKNKSSKRKHRKYSD-----SDSNSESDTNSDS 216
SS S +E +KKK S+ +K++ K +K + YS+ S+S SES+ +
Sbjct: 135 SSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEV 194
Query: 217 DDDKK-----RVKAKKK-KKKKKHKTKKKKNKKTKKESSDSS 252
KK R KA +K KKKKKHK KK KK SS S
Sbjct: 195 RAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDS 236
Score = 56.2 bits (134), Expect = 5e-08
Identities = 52/168 (30%), Positives = 81/168 (48%), Gaps = 29/168 (17%)
Query: 104 ERQSAEDYEKE-ESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
E + E+++KE E HR++ L E S + + E++ +
Sbjct: 52 EEKMNENWKKELEKHREKLLSGSES-------------------SSKKRQRKKKEKKKSG 92
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
+ SSSS S+S+ S +KK+ K + K+K+R + S+S S S+T SDS D
Sbjct: 93 RYSSSSSSSSDSSSSSSDSEDEDKKQGKRRK-KKKNRSHKSSES-SMSETESDSKDS--- 147
Query: 223 VKAKKKKK--KKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQ 268
+K KKK K +K K K +KK K S D S E LSE+ ++E+
Sbjct: 148 LKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPL--SSESLSESEYIEE 193
Score = 36.6 bits (83), Expect = 0.041
Identities = 28/111 (25%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 99 HCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEE 158
H +E S + + ++S ++ K++ + G ++ G S K D+ E
Sbjct: 130 HKSSESSMSETESDSKDSLKK---KKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLS 186
Query: 159 EVTH-QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNS 208
E + ++ + S E R+K T +++ KKK K K SK+K +K + S +S
Sbjct: 187 ESEYIEEVRAKKKKSSEEREKATEKTKKKKKHK-KHSKKKKKKAASSSPDS 236
Score = 34.7 bits (78), Expect = 0.16
Identities = 48/207 (23%), Positives = 77/207 (37%), Gaps = 26/207 (12%)
Query: 176 RKKKTSRS----RNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKK 231
+KKK S++ K K KHR+ S S S S KK+++K
Sbjct: 40 KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSS---------------KKRQRK 84
Query: 232 KKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDE 291
KK K K + + SSDSS S+ + + ++ E+ + T D
Sbjct: 85 KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDS 144
Query: 292 K-PLKYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYV------MSGS 344
K LK G + KR + L+SE + E V S
Sbjct: 145 KDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEE 204
Query: 345 RHRRMEAVRLRKENQIYSADEKRALAS 371
R + E + +K+++ +S +K+ AS
Sbjct: 205 REKATEKTKKKKKHKKHSKKKKKKAAS 231
Score = 30.8 bits (68), Expect = 2.3
Identities = 16/77 (20%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 188 KRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKT-KK 246
K + + K+ + ++ + + + + ++++ + + KK + KKK+ KK+ +
Sbjct: 35 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 94
Query: 247 ESSDSSCKDSEEDLSEA 263
SS SS DS S++
Sbjct: 95 SSSSSSSSDSSSSSSDS 111
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 64.3 bits (155), Expect = 2e-10
Identities = 33/84 (39%), Positives = 53/84 (63%), Gaps = 5/84 (5%)
Query: 173 EEHRKK--KTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSD---DDKKRVKAKK 227
E+HR+K S S +KK+++ K K+K +YS S S+S ++S SD +DKK+ K +K
Sbjct: 74 EKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRK 133
Query: 228 KKKKKKHKTKKKKNKKTKKESSDS 251
KKK + HK+ + +T+ +S DS
Sbjct: 134 KKKNRSHKSSESSMSETESDSKDS 157
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/162 (30%), Positives = 73/162 (45%), Gaps = 21/162 (12%)
Query: 112 EKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV-----THQKSS 166
E RQR+ KE+++ G + DS++ + + +H+ S
Sbjct: 85 ESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSE 144
Query: 167 SSDSNSEEH-----RKKKTSRSRNKKKRKNKSSKRKHRKYSD-----SDSNSESDTNSDS 216
SS S +E +KKK S+ +K++ K +K + YS+ S+S SES+ +
Sbjct: 145 SSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEV 204
Query: 217 DDDKK-----RVKAKKK-KKKKKHKTKKKKNKKTKKESSDSS 252
KK R KA +K KKKKKHK KK KK SS S
Sbjct: 205 RAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDS 246
Score = 56.2 bits (134), Expect = 5e-08
Identities = 52/168 (30%), Positives = 81/168 (48%), Gaps = 29/168 (17%)
Query: 104 ERQSAEDYEKE-ESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
E + E+++KE E HR++ L E S + + E++ +
Sbjct: 62 EEKMNENWKKELEKHREKLLSGSES-------------------SSKKRQRKKKEKKKSG 102
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
+ SSSS S+S+ S +KK+ K + K+K+R + S+S S S+T SDS D
Sbjct: 103 RYSSSSSSSSDSSSSSSDSEDEDKKQGKRRK-KKKNRSHKSSES-SMSETESDSKDS--- 157
Query: 223 VKAKKKKK--KKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQ 268
+K KKK K +K K K +KK K S D S E LSE+ ++E+
Sbjct: 158 LKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPL--SSESLSESEYIEE 203
Score = 36.6 bits (83), Expect = 0.041
Identities = 28/111 (25%), Positives = 53/111 (47%), Gaps = 5/111 (4%)
Query: 99 HCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEE 158
H +E S + + ++S ++ K++ + G ++ G S K D+ E
Sbjct: 140 HKSSESSMSETESDSKDSLKK---KKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLS 196
Query: 159 EVTH-QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNS 208
E + ++ + S E R+K T +++ KKK K K SK+K +K + S +S
Sbjct: 197 ESEYIEEVRAKKKKSSEEREKATEKTKKKKKHK-KHSKKKKKKAASSSPDS 246
Score = 34.7 bits (78), Expect = 0.16
Identities = 48/207 (23%), Positives = 77/207 (37%), Gaps = 26/207 (12%)
Query: 176 RKKKTSRS----RNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKK 231
+KKK S++ K K KHR+ S S S S KK+++K
Sbjct: 50 KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSS---------------KKRQRK 94
Query: 232 KKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDE 291
KK K K + + SSDSS S+ + + ++ E+ + T D
Sbjct: 95 KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDS 154
Query: 292 K-PLKYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYV------MSGS 344
K LK G + KR + L+SE + E V S
Sbjct: 155 KDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEE 214
Query: 345 RHRRMEAVRLRKENQIYSADEKRALAS 371
R + E + +K+++ +S +K+ AS
Sbjct: 215 REKATEKTKKKKKHKKHSKKKKKKAAS 241
Score = 30.8 bits (68), Expect = 2.3
Identities = 16/77 (20%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 188 KRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKT-KK 246
K + + K+ + ++ + + + + ++++ + + KK + KKK+ KK+ +
Sbjct: 45 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 104
Query: 247 ESSDSSCKDSEEDLSEA 263
SS SS DS S++
Sbjct: 105 SSSSSSSSDSSSSSSDS 121
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 62.4 bits (150), Expect = 7e-10
Identities = 88/359 (24%), Positives = 136/359 (37%), Gaps = 67/359 (18%)
Query: 11 EDIVGSRRRR---------RSSSGSPPSPQSRC---SSWDGCSRSHSRGREGLRPPWSEL 58
ED GSRRRR RS S S S +SR SS S+S SR R G R
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR------ 227
Query: 59 DVGALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHR 118
SRS SR R S S S R H + R ++D +E
Sbjct: 228 --------SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE---- 275
Query: 119 QRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKK 178
+++ + +G+ P+ PS H+ S S S S+E R +
Sbjct: 276 --KIQNNDNVGK---PKSRSPS--------------------RHKSKSKSRSRSQERRVE 310
Query: 179 KTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKK 238
+ R + R + S R+ R S S S S + S R K+K K+K +K ++
Sbjct: 311 EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS-------RSKSKDKRKGRKRSREE 363
Query: 239 KKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGH 298
+++ + S+ S K + S+A ++ DT D +P S++ + K
Sbjct: 364 SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT-DRSQSRSPSRSVSKEREHAKSES 422
Query: 299 ALLPGEG----AAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVR 353
+ G G A + ++ R + + L SE + + S S+ R A R
Sbjct: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASR 481
Score = 55.8 bits (133), Expect = 7e-08
Identities = 57/275 (20%), Positives = 105/275 (38%), Gaps = 39/275 (14%)
Query: 5 SRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALY 64
S+SS+S+ SR RS S S QSR S SRS S+ + R G
Sbjct: 211 SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSR----SHSAGKSR 266
Query: 65 PFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAED--------YEKEES 116
S+ + ++ N S S S + ++ER+ E+ +E+S
Sbjct: 267 SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKS 326
Query: 117 HRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHR 176
RQ R + R + G + +S S D R
Sbjct: 327 LRQSRSRSRSKGG---------------------------SRSRSRSRSKSKDKRKGRKR 359
Query: 177 KKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKT 236
++ SRSR++ + K++ S+++ K +S+ D+D + R ++ K+++H
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
Query: 237 KKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNV 271
+ ++ + ES ++ S + +PN+
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNL 454
Score = 39.3 bits (90), Expect = 0.006
Identities = 56/226 (24%), Positives = 83/226 (36%), Gaps = 61/226 (26%)
Query: 4 VSRS-SYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGA 62
VSR S + + SR R RS GS +SR S D + R RE R
Sbjct: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK-RKGRKRSREESR---------- 365
Query: 63 LYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRL 122
SRS SR + R R G + + +++ ED ++ +S R
Sbjct: 366 ----SRSRSRSKSERSRK-----------RGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
Query: 123 KERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKT-- 180
+ER EH E + +S ++ +N E + ++
Sbjct: 411 VSKER----------------------EHAKSESSQREGRGESENAGTNQETRSRSRSNS 448
Query: 181 ---------SRSRNKKKRKNKS-SKRKHRKYSDSDSNSESDTNSDS 216
SRSR+K K +S SK + R S S S S S ++S S
Sbjct: 449 KSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 62.4 bits (150), Expect = 7e-10
Identities = 37/177 (20%), Positives = 76/177 (42%), Gaps = 9/177 (5%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEE---- 158
+ER+S E+ E +++R +E+ER E G E G K + E++E
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 159 -----EVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTN 213
+ ++ +S E RK++ R K++ + K + K R+ +
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Query: 214 SDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPN 270
++ K++ + ++KK+++ K +KK+ ++ ++ K EE E Q N
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/159 (22%), Positives = 75/159 (47%), Gaps = 2/159 (1%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
+++ + +KEE R++R +E+E + K S E E +EE +
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRV 223
+ + EE K++ + R K++RK K + RK + + + N + KK
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK--ERKKER 200
Query: 224 KAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSE 262
+ K+++++KK + KK++ KK +++ ++ ++ E E
Sbjct: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239
Score = 52.0 bits (123), Expect = 9e-07
Identities = 24/109 (22%), Positives = 50/109 (45%)
Query: 154 VEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTN 213
+E +E ++ S E K+K R + +K+ + K K+ RK + +
Sbjct: 45 IETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREK 104
Query: 214 SDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSE 262
+ + ++K + KK+KK++ +K+ K ++ K+E K+ E E
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Score = 50.8 bits (120), Expect = 2e-06
Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 10/114 (8%)
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214
E E E+ +K + SE +KK R R K+KR+ + +++ R + + +
Sbjct: 40 EREREIETRKEGKKERESE---RKKERREREKRKREREKERKRERGKKEKKGERKKE--- 93
Query: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQ 268
+++R K +++K+ K+ + K+K+ KK KKE +S + E + E E+
Sbjct: 94 ----ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Score = 50.8 bits (120), Expect = 2e-06
Identities = 30/156 (19%), Positives = 70/156 (44%), Gaps = 9/156 (5%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
+ R+ E+ E EE ++++ +++ER S + + + E E+ +E
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKER---------GRTSKEGKERERKEERKREERKERER 149
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
+K + RKK+ + +K+ + K +RK RK + + + +++
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
Query: 223 VKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258
+ KKK+++KK + K ++ +KE K+ ++
Sbjct: 210 KERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/131 (19%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Query: 145 QLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKK--RKNKSSKRKHRKYS 202
++++ + E E E ++ E +++K R + +KK RK + +RK R+
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 203 DSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSE 262
+ E + K+R + K+ K+++ K ++K+ ++ ++E ++ E + E
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE-REKERERKE 162
Query: 263 ATWMEQPNVAD 273
E+ V +
Sbjct: 163 RKKRERKQVGE 173
Score = 35.0 bits (79), Expect = 0.12
Identities = 20/87 (22%), Positives = 44/87 (50%), Gaps = 11/87 (12%)
Query: 172 SEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKK 231
SE +++ +R + K++ +S ++K R+ + + + ++KR + KK+KK
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKR-------EREKERKRERGKKEKKG 88
Query: 232 KKHKTKKKKNKKTKKESSDSSCKDSEE 258
+KK+ ++ KK + K+ EE
Sbjct: 89 ----ERKKEERERKKRRREKENKEGEE 111
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 61.6 bits (148), Expect = 1e-09
Identities = 36/121 (29%), Positives = 66/121 (54%), Gaps = 2/121 (1%)
Query: 139 PSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKK-RKNKSSKRK 197
PS ++ + +E VE + +T ++ + KKK + R KKK +K++S +K
Sbjct: 195 PSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKK 254
Query: 198 HRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSE 257
H+ S S S+S S +++++ + ++ K+KK + K K+KKNK + +SDS KD
Sbjct: 255 HKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRK-KRKKNKCSGHNNSDSEEKDKS 313
Query: 258 E 258
+
Sbjct: 314 K 314
Score = 50.8 bits (120), Expect = 2e-06
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 162 HQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKK 221
H+ SSSS S+S +TS S ++ + NK K + +K + + ++++S+ D K
Sbjct: 255 HKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSK 314
Query: 222 RVKAKKKKKKKKHKTKKKKNKK--TKKESS--DSSCKDSEEDLSEATWMEQP 269
+ K ++ H +K K K K ESS DS S+ D T P
Sbjct: 315 KRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSP 366
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 16/108 (14%)
Query: 161 THQKSSSSDSNSEEHRKKKTSRSRNK--------KKRKNKSSKRK-HRKYSDSDSNSESD 211
T + SS S+SN++E + ++ R +NK + K+KS KRK H + S S N E
Sbjct: 273 TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKA 332
Query: 212 -------TNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSS 252
+ S +D K + KK + HK +K +KE S S
Sbjct: 333 KEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRS 380
Score = 39.3 bits (90), Expect = 0.006
Identities = 21/56 (37%), Positives = 31/56 (55%)
Query: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPN 270
D + KK+ K +KKKK +K ++K KK+K + SS SS S E ++ E N
Sbjct: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNN 284
Score = 33.9 bits (76), Expect = 0.27
Identities = 45/221 (20%), Positives = 89/221 (40%), Gaps = 41/221 (18%)
Query: 71 SRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGE 130
SR + + ++ + +SS S+S S +E +E KE+ ++++ K+ + G
Sbjct: 248 SRSKHKKHKSSSSSSSSSSSSSSTET-----SESSSESESNNKEKKIQRKKRKKNKCSGH 302
Query: 131 LGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKK------------ 178
+SD + ++ H++ SSS N E+ ++K
Sbjct: 303 N---------------NSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRED 347
Query: 179 -KTSRSR-NKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKT 236
K S S +KK R +K S K S+ S + ++ +R +++ K+ +T
Sbjct: 348 SKWSHSDSDKKSRTHKHSPEKR----GSERKEGSSRSHGREERSRRSRSRSPGSYKQRET 403
Query: 237 KKKKNKKTKKESS---DSSCKDSEEDLSEATWMEQPNVADT 274
+K+ + +E S DS ++ E + E P T
Sbjct: 404 RKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHT 444
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 13/160 (8%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
+R+S E+ E +++R +E+ER E G E + E +E +
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKE------------KKKRKKRERGKERERK 78
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDD-KKR 222
+ E K++ R + KKKR+ K R+ RK E + + KKR
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Query: 223 VKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSE 262
K K++K++K+ K + K+ +K KK + K E + E
Sbjct: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178
Score = 60.5 bits (145), Expect = 3e-09
Identities = 37/144 (25%), Positives = 67/144 (46%), Gaps = 17/144 (11%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
E+Q E EKE R++ K+RER Q E ++ +E +
Sbjct: 83 EKQRKERREKERRKRKKEKKKRER----------------KQRGRRERKKKKERKERERE 126
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSS-KRKHRKYSDSDSNSESDTNSDSDDDKKR 222
+ ++ RKKK + R ++K + K KRK RK + + E + + +++
Sbjct: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
Query: 223 VKAKKKKKKKKHKTKKKKNKKTKK 246
+ ++KK++KK + KKK+ KK +K
Sbjct: 187 ERRERKKERKKERRKKKERKKDRK 210
Score = 48.9 bits (115), Expect = 8e-06
Identities = 24/96 (25%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 152 TPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESD 211
T E E + ++ E+ RK++ + KK++K + K + RK + + +
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 212 TNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKE 247
+ +KR K KKK+++K+ +++K KK +KE
Sbjct: 90 REKER---RKRKKEKKKRERKQRGRRERKKKKERKE 122
Score = 45.8 bits (107), Expect = 7e-05
Identities = 18/80 (22%), Positives = 42/80 (52%)
Query: 167 SSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAK 226
S E +KK R R K+KR+ + +++ R + + + + + +K + +
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Query: 227 KKKKKKKHKTKKKKNKKTKK 246
+K++++K + K+KK KK ++
Sbjct: 86 RKERREKERRKRKKEKKKRE 105
Score = 31.6 bits (70), Expect = 1.3
Identities = 19/86 (22%), Positives = 39/86 (45%)
Query: 177 KKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKT 236
K +SR+ K + + H + SE + +KR + K++K+++ K
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKE 62
Query: 237 KKKKNKKTKKESSDSSCKDSEEDLSE 262
KKK+ K+ + + + K+ E+ E
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKE 88
>gi|27883882 P18SRP protein [Homo sapiens]
Length = 155
Score = 61.2 bits (147), Expect = 2e-09
Identities = 39/110 (35%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 148 SDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSN 207
S E + E+EE Q N EE +KK+ S+ + K K+K K R YS S +
Sbjct: 48 SSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRK------RSYSSSSTE 101
Query: 208 SESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSE 257
++ KK K +KK K KK K KK+ KK KKE S+ SE
Sbjct: 102 EDTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSE 151
Score = 59.7 bits (143), Expect = 5e-09
Identities = 40/113 (35%), Positives = 57/113 (50%), Gaps = 13/113 (11%)
Query: 159 EVTHQKSSSSDSNSEEHRK------KKTSRSRNKKKRKNKSS--KRKHRKYSDSDSNSES 210
+V+ S SD +EE K K+ + KKK K+K +K RK S S S++E
Sbjct: 43 DVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEE 102
Query: 211 DTNSDSDD-----DKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258
DT+ +KK+ K K KK K HK +KKK KK K S+ +S + S +
Sbjct: 103 DTSKQKKQKYQKKEKKKEKKSKSKKGKHHKKEKKKRKKEKHSSTPNSSEFSRK 155
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/183 (31%), Positives = 82/183 (44%), Gaps = 35/183 (19%)
Query: 104 ERQSAEDYEKE-ESHRQRRL-------KERERIGELGAPEVWGPSPKFPQLDSDEHTPVE 155
E + E+++KE E R++ L K+RER + S S + E
Sbjct: 62 EEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSE 121
Query: 156 DEEEVTHQKS------SSSDSNSEEHRKKKTSRSRNKKKRKNKS-----------SKRKH 198
DEE+ ++ S S S H + S+ KKK+K+K SK++
Sbjct: 122 DEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRK 181
Query: 199 RKYSD-----SDSNSESDTNSDSDDDKK-----RVKAKKKKKKKKHKTKKKKNKKTKKES 248
+ Y D S+S+SESD D KK R +AK+K KKKK K KK +KK KK+S
Sbjct: 182 KSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKS 241
Query: 249 SDS 251
S
Sbjct: 242 GSS 244
Score = 59.3 bits (142), Expect = 6e-09
Identities = 51/189 (26%), Positives = 80/189 (42%), Gaps = 30/189 (15%)
Query: 67 SRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERE 126
S S R R + + + SS S+S S + +ED EK++ R+++ K R
Sbjct: 86 SSSKKRERKKKRKKKSCRSSSSSSSSDS-------SSSSSDSEDEEKKQGKRRKKKKNRS 138
Query: 127 RIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNK 186
+ S H + +E +K S D E K+K RS +K
Sbjct: 139 ----------------YKSSQSSTHESESESKESVKKKKKSKD----ETEKEKDVRSLSK 178
Query: 187 KKRKNKSSKRKHRKYSDSDSNSESDTNSDSD---DDKKRVKAKKKKKKKKHKTKKKKNKK 243
K++K+ + S S+S+ E D + +++++ K K KKKKKK K K KK
Sbjct: 179 KRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKK 238
Query: 244 TKKESSDSS 252
K SS S
Sbjct: 239 KKSGSSHKS 247
Score = 52.4 bits (124), Expect = 7e-07
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 145 QLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDS 204
+L S + + E +K S S+S +S S + + + K KR+ +K + S
Sbjct: 79 KLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRS 138
Query: 205 DSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTK-----KKKNKKT----KKESSDSSCK- 254
+S+S T+ + K+ VK KKK K + K K KK KK+ K SS+SS +
Sbjct: 139 YKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSES 198
Query: 255 DSEEDL 260
D EED+
Sbjct: 199 DYEEDV 204
Score = 36.6 bits (83), Expect = 0.041
Identities = 40/214 (18%), Positives = 77/214 (35%), Gaps = 47/214 (21%)
Query: 186 KKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTK 245
KK+ +NK + K ++ + + + + ++++ + + KK + KKK+ KK+
Sbjct: 45 KKQLENKKTGSK--ALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
Query: 246 KESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHALLPGEG 305
+ SS SS DS S+ S+DE+
Sbjct: 103 RSSSSSSSSDSSSSSSD-------------------------SEDEEK------------ 125
Query: 306 AAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVRLRKENQIYSADE 365
K GKR ++ S + + E + ++ KE + S +
Sbjct: 126 -------KQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSK 178
Query: 366 KRALASFNQEERRKRESKILASFREMVHKKTKEK 399
KR S+ ++ ES + + E V K K +
Sbjct: 179 KRK-KSYPDDKPLSSESSSESDYEEDVQAKKKRR 211
Score = 34.3 bits (77), Expect = 0.20
Identities = 27/126 (21%), Positives = 48/126 (38%), Gaps = 24/126 (19%)
Query: 173 EEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKK- 231
EE +K+ ++ K K + + + E + + KKR + KK+KKK
Sbjct: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101
Query: 232 -----------------------KKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQ 268
KK ++KK K +SS SS +SE + E+ ++
Sbjct: 102 CRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKK 161
Query: 269 PNVADT 274
+ +T
Sbjct: 162 KSKDET 167
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 60.8 bits (146), Expect = 2e-09
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 15/143 (10%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
ERQ+ +D + + R ++RER + + + D D E E E
Sbjct: 154 ERQTEKDRDGQRETETERERDREREKQ---------KERETERDRDRQRDTEKERE---- 200
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRV 223
+D + RK +T R R + + + R+ + D D E D D +++K+
Sbjct: 201 --RQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKE 258
Query: 224 KAKKKKKKKKHKTKKKKNKKTKK 246
+ K++KK++K K K++K ++ KK
Sbjct: 259 RKKERKKERKEKKKEEKRREDKK 281
Score = 59.3 bits (142), Expect = 6e-09
Identities = 32/168 (19%), Positives = 75/168 (44%), Gaps = 13/168 (7%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
E+Q + E++ + R ++RE+ E + D T E E + +
Sbjct: 128 EKQKGRERERDRGRERERDRDREKERERQTEK---------DRDGQRETETERERDRERE 178
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRK----HRKYSDSDSNSESDTNSDSDDD 219
K ++ + R++ T + R ++ + + +RK ++ +D + E+D + D
Sbjct: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238
Query: 220 KKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWME 267
+ R K + +++ +K + KK++ K+ KKE + ++ + + W E
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
Score = 52.4 bits (124), Expect = 7e-07
Identities = 36/162 (22%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 105 RQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQK 164
R+ D +E + R KERER E G + + D + E E +
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKDRD---GQRETETERERDREREKQKERETERDR 189
Query: 165 SSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRV- 223
D+ E+ R+++T R R+++++ +R+ + + +++ + D D K+R
Sbjct: 190 DRQRDT--EKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDR 247
Query: 224 ----KAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLS 261
K ++KK++KK + K++K KK +++ + + E +S
Sbjct: 248 ERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289
Score = 50.4 bits (119), Expect = 3e-06
Identities = 34/172 (19%), Positives = 64/172 (37%), Gaps = 23/172 (13%)
Query: 125 RERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTS--- 181
R R+G +P WG D D+ D +K D + R++K
Sbjct: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN 110
Query: 182 --------------RSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDD------KK 221
R R K+K + + R + D D E + ++ D D +
Sbjct: 111 RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE 170
Query: 222 RVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVAD 273
R + ++++K+K+ +T++ ++++ E D E D T E+ D
Sbjct: 171 RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETD 222
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 60.5 bits (145), Expect = 3e-09
Identities = 36/157 (22%), Positives = 77/157 (49%), Gaps = 6/157 (3%)
Query: 95 RYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPV 154
R +H Y+ R + + +++ + R+ + R R E E S K + S+EH
Sbjct: 34 RASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK--KHKSEEHNDK 91
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214
E + ++ +SS++ + H++K+ SR + +++S +R+HR S S + S
Sbjct: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR----SRSRERKKSRS 147
Query: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDS 251
S + KK +++KK + +++++K + + S S
Sbjct: 148 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 184
Score = 51.6 bits (122), Expect = 1e-06
Identities = 56/228 (24%), Positives = 91/228 (39%), Gaps = 35/228 (15%)
Query: 17 RRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFSRSGSRGRLP 76
R +++ S SP++ + SRS SR RE R +S + GR
Sbjct: 20 RDKKKEQSEVSVSPRASKHHY---SRSRSRSRERKR---------------KSDNEGRKH 61
Query: 77 RFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEV 136
R R S S G R+ + ++ +E++ +E H + +ER E G
Sbjct: 62 RSR--------SRSKEGRRHESKDKSSKKHKSEEHNDKE-HSSDKGRERLNSSENGEDRH 112
Query: 137 WGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKR 196
K + S + + + + + RKK SRSR +KK +++S +R
Sbjct: 113 KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 172
Query: 197 KHRKYSDSDS--------NSESDTNSDSDDDKKRVKAKKKKKKKKHKT 236
K R S S S S S T S S D KKR++ ++ + +T
Sbjct: 173 KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRT 220
Score = 46.2 bits (108), Expect = 5e-05
Identities = 25/117 (21%), Positives = 58/117 (49%), Gaps = 10/117 (8%)
Query: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESD------TNS 214
+ ++ SD+ +HR + S+ + + K+KSSK KH+ +D SD +S
Sbjct: 47 SRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSS 105
Query: 215 DSDDDKKRVKAKKKKKKKKH---KTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQ 268
++ +D+ + K +K + + H ++++++++ +E S + E S + E+
Sbjct: 106 ENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER 162
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 166 SSSDSNSEEHRKKKTSRSRNKKKRKNK---SSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
++SD+ + +KTS R+KKK +++ S + YS S S S ++ +K
Sbjct: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
Query: 223 VKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258
+ K+ ++H++K K +KK K E + S++
Sbjct: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDK 97
Score = 39.7 bits (91), Expect = 0.005
Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 7/118 (5%)
Query: 147 DSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNK---KKRKNKSSKRKHRKYSD 203
+ D P + + +K S S S K SRSR++ +KRK+ + RKHR
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR---- 62
Query: 204 SDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLS 261
S S S+ +S D + ++ K+H + K + + E+ + K E S
Sbjct: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 60.1 bits (144), Expect = 3e-09
Identities = 35/153 (22%), Positives = 77/153 (50%), Gaps = 3/153 (1%)
Query: 95 RYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPV 154
R+ + ER D EKE ++ R ++R+R E E + Q + T
Sbjct: 36 RHRQRDRHRERDRQTDREKERERQKERDRQRQRERETER-ETERQRERQRQRERKRQTDR 94
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214
E +++ ++ +D N E R +K R R+K+ + + +R+ ++ + + + +
Sbjct: 95 ERDKDRDRERKRETDRNRE--RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKR 152
Query: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKE 247
++D +++R ++++KK++ K +KK+ K+ KKE
Sbjct: 153 ETDRERQRWAEREERKKERKKERKKERKEKKKE 185
Score = 54.3 bits (129), Expect = 2e-07
Identities = 37/176 (21%), Positives = 75/176 (42%), Gaps = 13/176 (7%)
Query: 104 ERQSAEDYEKEESHRQR-RLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
+R+ E+E HRQR R +ER+R + E + Q + T E E +
Sbjct: 24 QRERENQTERENRHRQRDRHRERDRQTDR-EKERERQKERDRQRQRERETERETERQRER 82
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
Q+ ++ R K R R ++ +N+ RK + D + E D + ++R
Sbjct: 83 QRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRER 142
Query: 223 VKAKKKKKKK-----------KHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWME 267
+ +++++K+ + + KK++ K+ KKE + ++ + + W E
Sbjct: 143 ERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 58.9 bits (141), Expect = 8e-09
Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 10/103 (9%)
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKK-------KRKNKSSKRKHRKYSDSDSN 207
E+EE+ +K + E+ +KKKT + +K KRK K K+K + + +
Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80
Query: 208 SESDTNSDSDDDKKRVKAKKKKKKKKHKT---KKKKNKKTKKE 247
E + + + ++ R + KKKK+++K + KKK+ +KTKK+
Sbjct: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 49.3 bits (116), Expect = 6e-06
Identities = 21/90 (23%), Positives = 49/90 (54%)
Query: 173 EEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKK 232
++ +KK+T + ++ + + K RK + E + + + +KR + ++++KK+
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 233 KHKTKKKKNKKTKKESSDSSCKDSEEDLSE 262
K K KKKK ++ ++E + ++ EE+ E
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92
Score = 48.1 bits (113), Expect = 1e-05
Identities = 21/105 (20%), Positives = 51/105 (48%), Gaps = 13/105 (12%)
Query: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKH-------------RKY 201
E+ EE + + ++K+ + + KKK+ ++ KRK +K
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70
Query: 202 SDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKK 246
+ + E + + +++++ + +++KKKKK + K+++ +K KK
Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/89 (23%), Positives = 51/89 (57%), Gaps = 6/89 (6%)
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNK-SSKRKHRKYSDSDSNSESDTNSDSDDDKK 221
+K + +EE +++ + K+KRK K K K +K +++ E + +++KK
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE-----EEEKK 61
Query: 222 RVKAKKKKKKKKHKTKKKKNKKTKKESSD 250
R + +KKKK+++ + ++++ ++ +KE +
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEE 90
Score = 42.7 bits (99), Expect = 6e-04
Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 186 KKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKK------KKKKHKTKKK 239
KKK+K K ++ + + + +K++ K KKKK +K+K + +KK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 240 KNKKTKKESSDSSCKDSEEDLSE 262
+ +K KK+ + ++ EE+ E
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEE 84
Score = 42.4 bits (98), Expect = 8e-04
Identities = 21/77 (27%), Positives = 38/77 (49%)
Query: 186 KKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTK 245
KKK+K K + + +++ E + +KR + +KKKK K+ + +K+K ++ K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 246 KESSDSSCKDSEEDLSE 262
K K EE+ E
Sbjct: 61 KRKRKRKKKKEEEEREE 77
Score = 40.0 bits (92), Expect = 0.004
Identities = 17/77 (22%), Positives = 39/77 (50%)
Query: 192 KSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDS 251
K K+K ++ +++ E++ + + +K + +K+K+K+K K K+ K+ +KE +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 252 SCKDSEEDLSEATWMEQ 268
K + E E+
Sbjct: 61 KRKRKRKKKKEEEEREE 77
Score = 39.3 bits (90), Expect = 0.006
Identities = 21/97 (21%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
+R+ +++E ++++ KE E+ E E + + + +E E+EEE
Sbjct: 28 KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE---- 83
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRK 200
+ EE R++K + R +K+ + + K++ RK
Sbjct: 84 -EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119
Score = 38.1 bits (87), Expect = 0.014
Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 20/94 (21%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
E+R+ E+ EK+ ++++ KE E + +E E+EE+
Sbjct: 50 EKRKEKEEEEKKRKRKRKKKKEEE--------------------EREEEEEEEEEEKEEE 89
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKR 196
+K ++ R++K KKKR+ K+ K+
Sbjct: 90 EKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 37.7 bits (86), Expect = 0.019
Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 17/127 (13%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
EE + E+ E++E R+ + KE+ + E + + E EEE
Sbjct: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEK------------KKKTKETEKRKEKEEEEKK 61
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
+K EE R+++ +K+ + K R+ +K E + + KKR
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE-----EKKKKR 116
Query: 223 VKAKKKK 229
+ KKK
Sbjct: 117 RRKTKKK 123
>gi|21361576 zinc finger, CCHC domain containing 17 [Homo sapiens]
Length = 241
Score = 58.9 bits (141), Expect = 8e-09
Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 8/100 (8%)
Query: 143 FPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKR-KHRKY 201
F Q +++ + DEEE ++ S E K +R+ ++K++K K K+ + RK
Sbjct: 147 FMQPGGTKYSLIPDEEE------EKEEAKSAEFEKPDPTRNPSRKRKKEKKKKKHRDRKS 200
Query: 202 SDSDSN-SESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKK 240
SDSDS+ SESDT + K KA KKKKKKK KK K
Sbjct: 201 SDSDSSDSESDTGKRARHTSKDSKAAKKKKKKKKHKKKHK 240
Score = 35.0 bits (79), Expect = 0.12
Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 200 KYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEED 259
KYS E + S + +K + +K+K + KKKK++ K SDSS DSE D
Sbjct: 154 KYSLIPDEEEEKEEAKSAEFEKPDPTRNPSRKRKKEKKKKKHRDRKSSDSDSS--DSESD 211
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 58.5 bits (140), Expect = 1e-08
Identities = 30/115 (26%), Positives = 57/115 (49%)
Query: 158 EEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSD 217
E+ + K +++ +KKKT+ + KK K + K +K + + + + T + +
Sbjct: 18 EKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKE 77
Query: 218 DDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVA 272
+K++ K K+K+K+K+ + +KKK KK KK+ L A+W E A
Sbjct: 78 KEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAKVCGLEIASWSEMTTAA 132
Score = 47.0 bits (110), Expect = 3e-05
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 16/103 (15%)
Query: 138 GPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRK 197
G K + + T ++ +++ T +K +++ + KKT+ + K+K K K
Sbjct: 26 GRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEK----- 80
Query: 198 HRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKK 240
E + + + +K++ K KKKKKKKK K KKKK
Sbjct: 81 -----------EKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 113 KEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNS 172
+ ES R K + + ++ E W SP + + +++ Q +SS+S S
Sbjct: 63 ESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGS 122
Query: 173 EEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR---------- 222
EE + + K K K + + S S S S+S ++S+S++++++
Sbjct: 123 EEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDY 182
Query: 223 -VKAKKKKKKKKHKTKKKKNKK---TKKESSDSSCKDSEED 259
K K K +K ++++K K KK KK DSS +D +E+
Sbjct: 183 EPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEE 223
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/121 (23%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Query: 145 QLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDS 204
Q +S+ T E++ + K ++ RS KK++ + +++H+ S+S
Sbjct: 61 QSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNS 120
Query: 205 DSNSESDTNSDSDDDKKRVKAKKKKKK------KKHKTKKKKNKKTKKESSDSSCKDSEE 258
S +S ++ DSDD VK KK K + ++ + ++++E SSC ++E
Sbjct: 121 GSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETES 180
Query: 259 D 259
D
Sbjct: 181 D 181
Score = 42.4 bits (98), Expect = 8e-04
Identities = 38/151 (25%), Positives = 69/151 (45%), Gaps = 23/151 (15%)
Query: 103 EERQSAEDYEKEESHRQRRLKERE--RIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160
E+ S+ED + S +R+ + E ++ G+P Q SD E EEE
Sbjct: 124 EDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPS---------QSGSDS----ESEEE- 169
Query: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKR-KHRKYSDSDSNSESDTNSDSDDD 219
+KSS ++ S+ K K + + + K+K+ K+ +K DS+ E D D D+D
Sbjct: 170 -REKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDND 228
Query: 220 KKRVKAKKKKKKKKHKTKKKKNKKTKKESSD 250
K + +++ K++++ K +S D
Sbjct: 229 K-----RSSRRQATVNVSYKEDEEMKTDSDD 254
Score = 40.0 bits (92), Expect = 0.004
Identities = 58/269 (21%), Positives = 104/269 (38%), Gaps = 44/269 (16%)
Query: 156 DEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSD 215
DEE V + SS S+ + + + + SS + SDSDS SES + S+
Sbjct: 6 DEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGS--SDSDSGSESGSQSE 63
Query: 216 SDDDKKR---VKAKKKK---------------KKKKHKTKKKKNKKTKKESSDSSCKDSE 257
S+ D R V+AK K ++ KK++ ++ +++ SS SE
Sbjct: 64 SESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSE 123
Query: 258 EDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHALLPGEGAAMAEYVKAGKR 317
ED S + D+ D +S + K K+ G+ +
Sbjct: 124 EDSSSS--------EDSDD----------SSSEVKRKKHKDEDWQMSGSGSPSQSGSDSE 165
Query: 318 IPRRGEIGLTSEEIGSFECSGYVMS-----GSRHRRMEAVRLRKENQIYSADEKRALASF 372
E E +E V S S+ + + + +K+ QI S++E +
Sbjct: 166 SEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDY 225
Query: 373 NQEER-RKRESKILASFREMVHKKTKEKD 400
+ ++R +R++ + S++E KT D
Sbjct: 226 DNDKRSSRRQATVNVSYKEDEEMKTDSDD 254
Score = 36.2 bits (82), Expect = 0.054
Identities = 59/257 (22%), Positives = 97/257 (37%), Gaps = 33/257 (12%)
Query: 7 SSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPF 66
SS S+D GS S S S S SS G S S S G + SE D
Sbjct: 17 SSQSDDDSGSASGSGSGSSSGSSSDGS-SSQSGSSDSDSGSESGSQSE-SESDTSR---- 70
Query: 67 SRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERE 126
+ + + P+ F W +S S R +++Q +Q++ ++ +
Sbjct: 71 -ENKVQAKPPKVDGAEF---WKSSPSILAVQRSAILKKQQ-----------QQQQQQQHQ 115
Query: 127 RIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS-----SDSNSEEHRKKKT- 180
G+ E S S+ +E+ S S SDS SEE R+K +
Sbjct: 116 ASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSC 175
Query: 181 --SRSRNKKKRKNKSSKRKHRKYSDSDSN----SESDTNSDSDDDKKRVKAKKKKKKKKH 234
+ S + K K KS K ++R S + + +S +DD + K+ ++
Sbjct: 176 DETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQ 235
Query: 235 KTKKKKNKKTKKESSDS 251
T K+ ++ +DS
Sbjct: 236 ATVNVSYKEDEEMKTDS 252
Score = 34.3 bits (77), Expect = 0.20
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 155 EDEEEVTHQKSSSSD-SNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTN 213
+D + H K S S+ E+HRK RSR+ R N K R +SD S+S+ +
Sbjct: 1583 KDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDH--RSNLEGSLKDRSHSDHRSHSDHRLH 1640
Query: 214 SDSDDDKKRVKAKKKKKKKKH 234
SD + K + + H
Sbjct: 1641 SDHRSSSEYTHHKSSRDYRYH 1661
Score = 32.0 bits (71), Expect = 1.0
Identities = 31/140 (22%), Positives = 53/140 (37%), Gaps = 9/140 (6%)
Query: 148 SDEH-TPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDS 206
SD H T D + HQ S S+S ++ +S S K R K+ R YSD +
Sbjct: 1546 SDRHLTQYHDHHKDRHQGDSYKKSDSR--KRPYSSFSNGKDHRDWDHYKQDSRYYSDREK 1603
Query: 207 NSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSD--SSCKDSEEDLSEAT 264
+ + D + D + K + H++ + SS + K S + +
Sbjct: 1604 HRKLDDHRSRDHRSNLEGSLKDRSHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSD 1663
Query: 265 WMEQPNVADTMDLIGPEAPI 284
W + + GP +P+
Sbjct: 1664 WQMDHRASSS----GPRSPL 1679
Score = 30.4 bits (67), Expect = 3.0
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 180 TSRSRNKKKRKNKSSKR-KHRKYSDSDSNSESDTNSDSDDDK-KRVKAKKKKKKKK 233
+S+ R + +KNK+ K K ++ SDS+ SD DDDK K+ +++ KK
Sbjct: 1328 SSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRERSKK 1383
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 56.6 bits (135), Expect = 4e-08
Identities = 63/293 (21%), Positives = 110/293 (37%), Gaps = 52/293 (17%)
Query: 14 VGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFS--RSGS 71
VG + RSS G +P S S+ G ++ G G D G P RSG
Sbjct: 617 VGGEKIVRSSGGRMDAPASG-SACSGLNKQEPGGSHGSETE----DTGRSLPSKKERSGK 671
Query: 72 RGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGEL 131
R + + + +S R H+ E+ AE EK + ++R+ K+ +
Sbjct: 672 SHRHKKKKKHKKSSKHK------RKHKADTEEKSSKAESGEKSKKRKKRKRKKNK--SSA 723
Query: 132 GAPEVWGPSPKFP--------------QLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRK 177
A GP P+ P Q DS + +E + S+S++H
Sbjct: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG 783
Query: 178 KK--------TSRSRNKKKRKNKSSKRKHRKYSDSDSN---------------SESDTNS 214
+K + + R KR ++SS R D DS+ SE +
Sbjct: 784 RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEE 843
Query: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWME 267
DS + R +++ ++ H++ ++ + SSD SC + S+ ++ +
Sbjct: 844 DSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSD 896
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 8/212 (3%)
Query: 15 GSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALYPFSRSGSRGR 74
G++R RSS S PS S R H + E D G+ + SRS S R
Sbjct: 800 GTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRR 859
Query: 75 LPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGE---L 131
R+ + S S+ S + CY+ +R ++D + S R RR +R +
Sbjct: 860 HSSHRSSRRSYSSSSDASS---DQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDY 916
Query: 132 GAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKN 191
+ + K+ D D + + + R SRSR+K++ ++
Sbjct: 917 ASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS 976
Query: 192 KS--SKRKHRKYSDSDSNSESDTNSDSDDDKK 221
+ S ++ R YS S S + S K+
Sbjct: 977 TTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKR 1008
Score = 41.6 bits (96), Expect = 0.001
Identities = 63/273 (23%), Positives = 102/273 (37%), Gaps = 31/273 (11%)
Query: 5 SRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSE------- 57
++SS D + SGSP P+ R + D R EG E
Sbjct: 719 NKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSS 778
Query: 58 ------LDVGALYPFS---RSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSA 108
G L P S R+G++ R R + + SS HR Q +
Sbjct: 779 QDHGGRKHKGELPPSSCQRRAGTK-RSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYS 837
Query: 109 EDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSS 168
E+ E+E+S + + R R G + S + SD + D+ + Q+S S
Sbjct: 838 EEEEEEDSGSEHS-RSRSRSGRRHSSH--RSSRRSYSSSSDASS---DQSCYSRQRSYSD 891
Query: 169 DSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKK 228
DS S+ + RSR KR + S Y+ S S+ S SDDD ++ +
Sbjct: 892 DSYSD-----YSDRSRRHSKRSHDSD---DSDYASSKHRSKRHKYSSSDDDYSLSCSQSR 943
Query: 229 KKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLS 261
+ + H ++ +++ + SS S + S
Sbjct: 944 SRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRS 976
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 56.2 bits (134), Expect = 5e-08
Identities = 30/158 (18%), Positives = 84/158 (53%), Gaps = 6/158 (3%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAP-EVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
+R+ EKE + ++ R +E ER GE G + G + Q D+++ E E +
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEK----ERERQTDR 165
Query: 163 QKSSSSDSNSEEHRKKKTSRS-RNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKK 221
++ ++ N ++ R+++ +R R +++R+ + + ++S+ E + ++++ ++K
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 222 RVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEED 259
R +++ +++K + +++K + ++ S + +D E +
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Score = 51.2 bits (121), Expect = 2e-06
Identities = 28/160 (17%), Positives = 80/160 (50%), Gaps = 4/160 (2%)
Query: 106 QSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKS 165
Q+ +D + ++ R R+ KERER E E + + + D H + E +
Sbjct: 44 QAHKDADGDDRERNRQ-KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE 102
Query: 166 SSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVK- 224
+ ++ R ++ + RN++K + + ++R+ + D ++ + + D +K+R +
Sbjct: 103 KERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ 162
Query: 225 --AKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSE 262
+++++ ++++ K+++ +K ++E + + +E+ +E
Sbjct: 163 TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Score = 49.7 bits (117), Expect = 5e-06
Identities = 28/151 (18%), Positives = 73/151 (48%), Gaps = 9/151 (5%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
ER ++ E+E++ ++RR +ER+R E + S + + + + T E E +
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTED--RHSERGRERERERETETETERKRQTD 229
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSN-------SESDTNSDS 216
+ +E R+K+ R R ++ + +R+ + D D + ++D
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 217 DDDKKRVKAKKKKKKKKHKTKKKKNKKTKKE 247
++ R +K++++++ + ++++N+K ++E
Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERE 320
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/164 (17%), Positives = 74/164 (45%), Gaps = 21/164 (12%)
Query: 103 EERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTH 162
+ER+ D E++ + R KERER + + + E ++E T
Sbjct: 157 KERERQTDRERQRQTERNRQKERER--------------EKNRQERRERERQREKENKTE 202
Query: 163 QKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKR 222
+ S E R+ +T R ++ + + +RK + + + E + +++ DK+R
Sbjct: 203 DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER 262
Query: 223 VKAK-------KKKKKKKHKTKKKKNKKTKKESSDSSCKDSEED 259
+ + +++K+++ +T +K+ ++T+++ ++ + +
Sbjct: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Score = 47.0 bits (110), Expect = 3e-05
Identities = 32/174 (18%), Positives = 76/174 (43%), Gaps = 27/174 (15%)
Query: 103 EERQSAEDYEKEESHRQR---RLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEE 159
E R+ + + K + HR+R R KERER +D + E+E
Sbjct: 80 ERRREKDRHRKRDRHRERQRDREKERER-------------------QTDRERDRQREKE 120
Query: 160 VTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDD 219
QK ++ E R + +++ + + ++++ + +D + +++ N
Sbjct: 121 RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ---- 176
Query: 220 KKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVAD 273
K+R + K ++++++ + +++K KT+ S+ ++ E + T E+ D
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERG-RERERERETETETERKRQTD 229
Score = 45.4 bits (106), Expect = 9e-05
Identities = 29/160 (18%), Positives = 78/160 (48%), Gaps = 12/160 (7%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAP-EVWGPSPKFPQLDSD---EHTPVEDEEE 159
ER+ D E++ + R +E++ E + E + + D D + E E +
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 160 VTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDD 219
++ ++ + E RK++ R R +++ +N+ +R+ + + + E++ D +
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER----DRE 338
Query: 220 KKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEED 259
K+R ++K+K++ + +++N++T +E + ++ E +
Sbjct: 339 KER----ERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/144 (15%), Positives = 65/144 (45%), Gaps = 4/144 (2%)
Query: 125 RERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSR 184
R R G +P G D D+ +E ++ ++ ++ +K R R
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD----RKRERRR 83
Query: 185 NKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKT 244
K + + + R+ ++ + + ++D D +K+R + K+++++ + + ++ ++++T
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
Query: 245 KKESSDSSCKDSEEDLSEATWMEQ 268
+ +D+E++ T E+
Sbjct: 144 DGQRERERQRDAEKERERQTDRER 167
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/147 (19%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 104 ERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQ 163
+R++ D EKE +++R E +R + Q + E E E +
Sbjct: 330 QRETERDREKERERKRKRQTEMDR-------------ERNRQTGREGRRQAERERERERE 376
Query: 164 KSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSD--SDDDKK 221
+ S EE R++ R R K++ + R ++ ++ E D S+ + ++
Sbjct: 377 RDRQSAREREE-RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435
Query: 222 RVKAKKKKKKKKHKTKKKKNKKTKKES 248
R K K +++ ++ +T ++ ++ K+ +
Sbjct: 436 REKQKGRERDRERQTDRQAGRQRKRST 462
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 55.8 bits (133), Expect = 7e-08
Identities = 50/182 (27%), Positives = 86/182 (47%), Gaps = 19/182 (10%)
Query: 92 SGYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEH 151
+ YR + + + E +SA + H + ++KE ++ E E L D+
Sbjct: 387 TAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEEKKDLEESMEEA---------LKLDQE 437
Query: 152 TPVEDEEEVTHQKSSSSDSNSEEHRKK---KTSRSRNKKKRKNKSSKRKHRKYSDSDSNS 208
P+ EV + + DSNSE R++ K+ R R + R S K++ + D
Sbjct: 438 MPLT---EVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTEDKLK 494
Query: 209 ESDT-NSDSDDDKKRVKAKKKKKKKKHK-TKKKKNKKTKKESSDSSCKDSEEDLSEATWM 266
++DT N D DDD + + K+ + K T K+K KK KK+ + S KDS+E+ ++
Sbjct: 495 DNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQ--EDSDKDSDEEEEKSQER 552
Query: 267 EQ 268
E+
Sbjct: 553 EE 554
Score = 31.6 bits (70), Expect = 1.3
Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 9/118 (7%)
Query: 147 DSD-EHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKR---KHRKYS 202
D+D E+ V+D+ E +K N +K T + + KK +K + S + + + S
Sbjct: 495 DNDTENKDVDDDYETAEKK-----ENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKS 549
Query: 203 DSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDL 260
+ES +S+ ++D++ ++ K K K + K +K + S S+ D E L
Sbjct: 550 QEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVL 607
Score = 31.6 bits (70), Expect = 1.3
Identities = 33/144 (22%), Positives = 57/144 (39%), Gaps = 31/144 (21%)
Query: 150 EHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNK------------------KKRKN 191
++TP + E+++ Q+ S DS+ EE + ++ + +K K K
Sbjct: 522 KNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKV 581
Query: 192 KSSKRKHRK-YSDSDSNSESDT------------NSDSDDDKKRVKAKKKKKKKKHKTKK 238
K + K +K Y S ++E D N D+ K + K K K+
Sbjct: 582 KYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQ 641
Query: 239 KKNKKTKKESSDSSCKDSEEDLSE 262
KK K K++S +D E S+
Sbjct: 642 KKKAKNKEDSEKDEKRDEERQKSK 665
Score = 31.2 bits (69), Expect = 1.7
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 21/102 (20%)
Query: 155 EDEEEVTHQKSSSSDSNSE------EHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNS 208
E EEE T K +D+ ++ E +KK + +K K ++K +K DSD
Sbjct: 483 EIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK-- 540
Query: 209 ESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSD 250
DSD++ ++K +++ +T+ K + + +++ D
Sbjct: 541 ------DSDEE-------EEKSQEREETESKCDSEGEEDEED 569
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.123 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,412,208
Number of Sequences: 37866
Number of extensions: 916928
Number of successful extensions: 25910
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 747
Number of HSP's successfully gapped in prelim test: 723
Number of HSP's that attempted gapping in prelim test: 8339
Number of HSP's gapped (non-prelim): 8391
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.