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Search of human proteins with 13435145
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13435145 clusterin associated protein 1 isoform 2 [Homo
sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13435145 clusterin associated protein 1 isoform 2 [Homo sapiens] 488 e-138
gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens] 488 e-138
gi|115529449 upstream binding transcription factor, RNA polymera... 59 5e-09
gi|115529451 upstream binding transcription factor, RNA polymera... 59 5e-09
gi|7657671 upstream binding transcription factor, RNA polymerase... 59 5e-09
gi|55956788 nucleolin [Homo sapiens] 53 2e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 53 3e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 53 3e-07
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 48 7e-06
gi|42794779 myosin 18A isoform b [Homo sapiens] 48 7e-06
gi|58530840 desmoplakin isoform I [Homo sapiens] 46 3e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 46 3e-05
gi|222537714 taxilin beta [Homo sapiens] 45 4e-05
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 45 4e-05
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 45 4e-05
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 45 4e-05
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 45 4e-05
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 45 4e-05
gi|217035164 coiled-coil domain containing 27 [Homo sapiens] 45 4e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 45 6e-05
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 45 8e-05
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 45 8e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 45 8e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 45 8e-05
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 44 1e-04
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 44 1e-04
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 44 1e-04
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 44 1e-04
gi|216548091 leucine zipper protein 1 [Homo sapiens] 44 1e-04
gi|216548085 leucine zipper protein 1 [Homo sapiens] 44 1e-04
>gi|13435145 clusterin associated protein 1 isoform 2 [Homo sapiens]
Length = 247
Score = 488 bits (1257), Expect = e-138
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 60
MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER
Sbjct: 1 MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 60
Query: 61 NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE 120
NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE
Sbjct: 61 NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE 120
Query: 121 AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG 180
AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG
Sbjct: 121 AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG 180
Query: 181 RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL 240
RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL
Sbjct: 181 RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL 240
Query: 241 DESDNDF 247
DESDNDF
Sbjct: 241 DESDNDF 247
>gi|52345626 clusterin associated protein 1 isoform 1 [Homo sapiens]
Length = 413
Score = 488 bits (1257), Expect = e-138
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 60
MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER
Sbjct: 167 MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 226
Query: 61 NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE 120
NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE
Sbjct: 227 NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEE 286
Query: 121 AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG 180
AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG
Sbjct: 287 AKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG 346
Query: 181 RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL 240
RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL
Sbjct: 347 RPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPL 406
Query: 241 DESDNDF 247
DESDNDF
Sbjct: 407 DESDNDF 413
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 58.5 bits (140), Expect = 5e-09
Identities = 46/196 (23%), Positives = 85/196 (43%), Gaps = 26/196 (13%)
Query: 51 IEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDH 110
+++R +E+ +R+ Q + Y+K EE QKQY +L+ +++
Sbjct: 556 LKERMVEIGSRWQRISQSQK------EHYKKLAEEQQKQYKVHLD-----LWVKSLSPQD 604
Query: 111 HRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKP 170
+E + ++ ++ + + L+S S + D + EDDE + E EE
Sbjct: 605 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD---- 660
Query: 171 QTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKP 230
G + + + D++ED +E+E D ED+DD++DD EDE +
Sbjct: 661 -------ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSS 713
Query: 231 NRRVRKSEPLDESDND 246
+ S D SD+D
Sbjct: 714 S----SSSSGDSSDSD 725
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 58.5 bits (140), Expect = 5e-09
Identities = 46/196 (23%), Positives = 85/196 (43%), Gaps = 26/196 (13%)
Query: 51 IEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDH 110
+++R +E+ +R+ Q + Y+K EE QKQY +L+ +++
Sbjct: 556 LKERMVEIGSRWQRISQSQK------EHYKKLAEEQQKQYKVHLD-----LWVKSLSPQD 604
Query: 111 HRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKP 170
+E + ++ ++ + + L+S S + D + EDDE + E EE
Sbjct: 605 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD---- 660
Query: 171 QTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKP 230
G + + + D++ED +E+E D ED+DD++DD EDE +
Sbjct: 661 -------ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSS 713
Query: 231 NRRVRKSEPLDESDND 246
+ S D SD+D
Sbjct: 714 S----SSSSGDSSDSD 725
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 58.5 bits (140), Expect = 5e-09
Identities = 46/196 (23%), Positives = 85/196 (43%), Gaps = 26/196 (13%)
Query: 51 IEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDH 110
+++R +E+ +R+ Q + Y+K EE QKQY +L+ +++
Sbjct: 593 LKERMVEIGSRWQRISQSQK------EHYKKLAEEQQKQYKVHLD-----LWVKSLSPQD 641
Query: 111 HRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKP 170
+E + ++ ++ + + L+S S + D + EDDE + E EE
Sbjct: 642 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDD---- 697
Query: 171 QTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKP 230
G + + + D++ED +E+E D ED+DD++DD EDE +
Sbjct: 698 -------ENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSS 750
Query: 231 NRRVRKSEPLDESDND 246
+ S D SD+D
Sbjct: 751 S----SSSSGDSSDSD 762
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 53.1 bits (126), Expect = 2e-07
Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 21/118 (17%)
Query: 137 KRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSD 196
K K S+++ D D +ED+E D + +E AM+ +
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMK-------------AAAAAPAS 184
Query: 197 DNEDSEESEIDMEDDDDEDDDLEDESISLSPTK--------PNRRVRKSEPLDESDND 246
++ED E+ E D +DDDDE+DD E+E++ +P K P + +E DE ++D
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDD 242
Score = 51.6 bits (122), Expect = 6e-07
Identities = 32/94 (34%), Positives = 49/94 (52%), Gaps = 5/94 (5%)
Query: 146 DDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGK-RIVGTMQGGDSDDNEDSEES 204
DD D D E+D+S+ E E K + A +++ P K + V + + DD ++ ++
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVV----PVKAKNVAEDEDEEEDDEDEDDDD 249
Query: 205 EIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSE 238
+ D EDDDDEDD+ E+E P K RK E
Sbjct: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283
Score = 47.4 bits (111), Expect = 1e-05
Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 15/113 (13%)
Query: 144 SNDDSDIDIQEDDESDSELEERRLPKPQTAMEML-MQGRPGKRIVGTMQGG--------- 193
+++D D + EDDE D + EE + AME +G+ ++V
Sbjct: 183 ASEDEDDEDDEDDEDDDDDEED--DSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240
Query: 194 ---DSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDES 243
D DD++D ++ + D EDD++E+++ E+E + +P K + + K + E+
Sbjct: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEA 293
Score = 34.7 bits (78), Expect = 0.079
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 182 PGKR-----IVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRK 236
PGK+ G G ++ + EE + D E+D+++D+D +++ + P
Sbjct: 122 PGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA 181
Query: 237 SEPLDESDND 246
DE D D
Sbjct: 182 PASEDEDDED 191
Score = 30.0 bits (66), Expect = 1.9
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 15/78 (19%)
Query: 182 PGKRIVGT------------MQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTK 229
PGK +V T + G + EDS+E E D + ++DE+DD EDE +
Sbjct: 114 PGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDD-DSEEDEEDD-EDEDEDEDEIE 171
Query: 230 P-NRRVRKSEPLDESDND 246
P + + P E ++D
Sbjct: 172 PAAMKAAAAAPASEDEDD 189
Score = 29.3 bits (64), Expect = 3.3
Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 6/57 (10%)
Query: 129 QNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKR 185
+N ++E++ +DD D D ++DD+ D E EE + E ++ PGKR
Sbjct: 230 KNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEE------EEEEEEPVKEAPGKR 280
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/229 (21%), Positives = 100/229 (43%), Gaps = 28/229 (12%)
Query: 20 RIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEY 79
RIA K +L +++ N++SDE E E +KR P
Sbjct: 1232 RIAKKMLLEEIKA------NLSSDEDGSSDD------EPEEGKKRTGKQNEENP----GD 1275
Query: 80 EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRL 139
E+ + ++ + D+ E+ + Y + L + E K T ++K +R
Sbjct: 1276 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335
Query: 140 LKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG-------RPGKRIVGTMQG 192
+ S ++DSD E SE E+ + P+ ++A + ++ + +R + +
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1395
Query: 193 GDSDDNEDSEESEIDMEDDDDEDDDLEDE-----SISLSPTKPNRRVRK 236
S++ +SEE E + E++++E+++ E+E S SP K +++RK
Sbjct: 1396 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK 1444
Score = 28.9 bits (63), Expect = 4.3
Identities = 34/144 (23%), Positives = 62/144 (43%), Gaps = 28/144 (19%)
Query: 104 EQQLEDHHRMEQERFEEAKNTLCLIQ--NKLKEEEKRLLKSGSNDDSDIDIQEDDES--- 158
E+ ED+ + +Q + K + + N L+ KR ++ S DI++DD++
Sbjct: 1121 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK-QADITSSSSSDIEDDDQNSIG 1179
Query: 159 DSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDL 218
+ +E+++ KP T +L G Q S D S+ + ++DDDD++D
Sbjct: 1180 EGSSDEQKI-KPVTENLVLSSH------TGFCQS--SGDEALSKSVPVTVDDDDDDND-- 1228
Query: 219 EDESISLSPTKPNRRVRKSEPLDE 242
P R+ K L+E
Sbjct: 1229 -----------PENRIAKKMLLEE 1241
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/229 (21%), Positives = 100/229 (43%), Gaps = 28/229 (12%)
Query: 20 RIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEY 79
RIA K +L +++ N++SDE E E +KR P
Sbjct: 1270 RIAKKMLLEEIKA------NLSSDEDGSSDD------EPEEGKKRTGKQNEENP----GD 1313
Query: 80 EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRL 139
E+ + ++ + D+ E+ + Y + L + E K T ++K +R
Sbjct: 1314 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1373
Query: 140 LKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG-------RPGKRIVGTMQG 192
+ S ++DSD E SE E+ + P+ ++A + ++ + +R + +
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1433
Query: 193 GDSDDNEDSEESEIDMEDDDDEDDDLEDE-----SISLSPTKPNRRVRK 236
S++ +SEE E + E++++E+++ E+E S SP K +++RK
Sbjct: 1434 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK 1482
Score = 28.9 bits (63), Expect = 4.3
Identities = 34/144 (23%), Positives = 62/144 (43%), Gaps = 28/144 (19%)
Query: 104 EQQLEDHHRMEQERFEEAKNTLCLIQ--NKLKEEEKRLLKSGSNDDSDIDIQEDDES--- 158
E+ ED+ + +Q + K + + N L+ KR ++ S DI++DD++
Sbjct: 1159 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK-QADITSSSSSDIEDDDQNSIG 1217
Query: 159 DSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDL 218
+ +E+++ KP T +L G Q S D S+ + ++DDDD++D
Sbjct: 1218 EGSSDEQKI-KPVTENLVLSSH------TGFCQS--SGDEALSKSVPVTVDDDDDDND-- 1266
Query: 219 EDESISLSPTKPNRRVRKSEPLDE 242
P R+ K L+E
Sbjct: 1267 -----------PENRIAKKMLLEE 1279
Score = 28.1 bits (61), Expect = 7.4
Identities = 36/149 (24%), Positives = 60/149 (40%), Gaps = 19/149 (12%)
Query: 100 LTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESD 159
L L Q+L D E EE + L N + ++ SGSN D + +E+ S
Sbjct: 11 LNTLVQKLHDFLAHSSEESEETSSPPRLAMN---QNTDKISGSGSNSDMMENSKEEGTSS 67
Query: 160 SELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLE 219
SE K +++ + +P IV D + D E D +++ E+D
Sbjct: 68 SE-------KSKSSGSSRSKRKPS--IVTKYVESDDEKPLDDETVNEDASNENSEND--- 115
Query: 220 DESISLSPTKPNRRVRKSEP-LDESDNDF 247
I++ + + EP L+E +DF
Sbjct: 116 ---ITMQSLPKGTVIVQPEPVLNEDKDDF 141
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 48.1 bits (113), Expect = 7e-06
Identities = 50/254 (19%), Positives = 112/254 (44%), Gaps = 33/254 (12%)
Query: 11 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIE----------KRKLELER 60
++ +K ++ A ++ L +Q +D +N++ ++ LE ++E K +++LER
Sbjct: 992 KLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLER 1051
Query: 61 NRKRLE-TLQSVRPCFMD---EYEKTEEELQKQYDTYLE-----------------KFQN 99
N+++LE L+ + +D + ++ +E L+K+ Y + K +
Sbjct: 1052 NKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKE 1111
Query: 100 LTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESD 159
L ++LE+ E+ + + +L+E +RL ++G + I++ + E++
Sbjct: 1112 LQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAE 1171
Query: 160 SELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDD--EDDD 217
R L + E ++ K + G+ DN + +++ E + E DD
Sbjct: 1172 FLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDD 1231
Query: 218 LEDESISLSPTKPN 231
L S+S +K N
Sbjct: 1232 LSSSMESVSKSKAN 1245
Score = 37.7 bits (86), Expect = 0.009
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 17/147 (11%)
Query: 25 EILTQVQKTKDLLNNVASDEANLE---AKIEKRKLELERNRKRL--------ETLQSV-- 71
E+ + +K +D + + D +LE AK+EK K E K L ET+ +
Sbjct: 936 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTR 995
Query: 72 -RPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQN 130
+ + +++ ++LQ + D + + LEQQ+ED +E +E K + L +N
Sbjct: 996 EKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVED---LESSLEQEKKLRVDLERN 1052
Query: 131 KLKEEEKRLLKSGSNDDSDIDIQEDDE 157
K K E L S D + D Q+ DE
Sbjct: 1053 KRKLEGDLKLAQESILDLENDKQQLDE 1079
Score = 33.9 bits (76), Expect = 0.13
Identities = 36/170 (21%), Positives = 75/170 (44%), Gaps = 22/170 (12%)
Query: 3 TEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNR 62
T+AI R E+ E +K + +++ QV+ ++ + L+ ++E +++ER
Sbjct: 1378 TDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
Query: 63 KRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERF---- 118
L D+ ++ +++ ++ T E+ Q LE L++ + E F
Sbjct: 1438 SLAAAL--------DKKQRNFDKVLAEWKTKCEESQ--AELEASLKESRSLSTELFKLKN 1487
Query: 119 --EEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERR 166
EEA + L ++ + K E+ + D I E+ ++ ELE+ R
Sbjct: 1488 AYEEALDQLETVKRENKNLEQEIA------DLTEQIAENGKTIHELEKSR 1531
Score = 31.6 bits (70), Expect = 0.67
Identities = 48/235 (20%), Positives = 94/235 (40%), Gaps = 46/235 (19%)
Query: 11 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANL-----------------EAKI-- 51
E+ ++E + ++++T VQ+ DL V ++ NL EAKI
Sbjct: 863 ELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKE 922
Query: 52 --------EKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYL 103
E+ EL +++LE S +D+ E T +++K+ K +NLT
Sbjct: 923 VTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT-- 980
Query: 104 EQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELE 163
E T+ KL E+K L ++ D+ +ED +
Sbjct: 981 ------------EELSGLDETIA----KLTREKKALQEAHQQALDDLQAEEDKVNSLNKT 1024
Query: 164 ERRLPKPQTAMEMLMQGRPGKRI-VGTMQGGDSDDNEDSEESEIDMEDDDDEDDD 217
+ +L + +E ++ R+ + + D + ++ES +D+E+D + D+
Sbjct: 1025 KSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDE 1079
Score = 28.5 bits (62), Expect = 5.6
Identities = 26/152 (17%), Positives = 68/152 (44%), Gaps = 3/152 (1%)
Query: 16 EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCF 75
EK+ R +++ L++ + + + S+ +++++ EL R + E++ S
Sbjct: 1247 EKICR-TLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRS 1305
Query: 76 MDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEE 135
+ + EEL++Q + + L + Q + +E++EE + +Q L +
Sbjct: 1306 KQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA 1365
Query: 136 EKRLLKSGSNDDSDI--DIQEDDESDSELEER 165
+ + + ++D +E +E+ +L +R
Sbjct: 1366 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1397
Score = 28.1 bits (61), Expect = 7.4
Identities = 41/190 (21%), Positives = 76/190 (40%), Gaps = 29/190 (15%)
Query: 77 DEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQ----------ERFEEAKNTLC 126
+E++KT++EL K E + L L Q+ D Q ER ++
Sbjct: 855 EEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKF 914
Query: 127 LIQNKLKEEEKRLLKSGSNDDSDIDIQ----------EDDESDSELEERRLPKPQTAMEM 176
++ K+KE +R + D+ +I+ + E E ++++ L + E
Sbjct: 915 QLEAKIKEVTER-----AEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 969
Query: 177 LMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDL---EDESISLSPTKPNRR 233
K + + G D + + E + E DDL ED+ SL+ TK ++
Sbjct: 970 HATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTK-SKL 1028
Query: 234 VRKSEPLDES 243
++ E L+ S
Sbjct: 1029 EQQVEDLESS 1038
Score = 28.1 bits (61), Expect = 7.4
Identities = 28/168 (16%), Positives = 72/168 (42%), Gaps = 5/168 (2%)
Query: 11 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERN-RKRLETLQ 69
E+ ++ K + + +I +++ + L + + ++ ++ + K E++R ++ E ++
Sbjct: 1526 ELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585
Query: 70 SVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQ 129
++ Y++T E +Q D + L++++E + + A
Sbjct: 1586 QLKR----NYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETL 1641
Query: 130 NKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEML 177
L+ + +L + + D + QED + + ERR Q +E L
Sbjct: 1642 KHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEEL 1689
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 48.1 bits (113), Expect = 7e-06
Identities = 45/216 (20%), Positives = 94/216 (43%), Gaps = 12/216 (5%)
Query: 11 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQS 70
++NE K + A+ + + + DL + +EAN E + + KL+ +++
Sbjct: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQL--EEANKEKQELQEKLQALQSQVEFLEQSM 1811
Query: 71 VRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQN 130
V + E EL+ + + + + L L +L+++ E+ E ++ +N
Sbjct: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKEN----MEKLTEERDQRIAAEN 1867
Query: 131 KLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQG-----RPGKR 185
+ KE+ KRL + + ++ E+++ ++ L ++E Q + +
Sbjct: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1927
Query: 186 IVGTMQGGDSDDNE-DSEESEIDMEDDDDEDDDLED 220
+G +Q D+ E D E I+ E D D D +LED
Sbjct: 1928 RIGDLQAAIEDEMESDENEDLINSEGDSDVDSELED 1963
Score = 41.6 bits (96), Expect = 6e-04
Identities = 53/257 (20%), Positives = 110/257 (42%), Gaps = 43/257 (16%)
Query: 15 TEKVMRIA--IKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLE----------LERNR 62
T+KV+ + +++I +Q K + L V +LEAK++ ++ E LE+ +
Sbjct: 1513 TQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAK 1572
Query: 63 KRLE-TLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNL-TYLEQQLEDHHRMEQERFEE 120
RLE ++ +R E E +EE+++ + +K + + LE++ ED ++ +E+ E
Sbjct: 1573 LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREK-RE 1631
Query: 121 AKNTLCLIQNKLK----EEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEM 176
+ L + +++ E EKRL K D + + L Q ++
Sbjct: 1632 LEGKLATLSDQVNRRDFESEKRLRK-----------------DLKRTKALLADAQLMLDH 1674
Query: 177 LMQGRPGKRIVGTMQGGDSDDN-------EDSEESEIDMEDDDDEDDDLEDESISLSPTK 229
L P KR + ++ + + + E+++ED + DD+ +L
Sbjct: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
Query: 230 PNRRVRKSEPLDESDND 246
+ K+E + + D
Sbjct: 1735 SRLQREKNEIQNRLEED 1751
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 45.8 bits (107), Expect = 3e-05
Identities = 36/152 (23%), Positives = 76/152 (50%), Gaps = 19/152 (12%)
Query: 11 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQS 70
E+++ ++ + + ++++ TQ++ + + + D+A I+ + E+ER ++ ++ +
Sbjct: 1439 EVSQRKQQLEVELRQV-TQMRTEESVRYKQSLDDA--AKTIQDKNKEIERLKQLIDKETN 1495
Query: 71 VRPCFMDE---YEKTEEELQKQYDTYLEKFQNLTYLEQQLE----DHHRMEQER------ 117
R C DE ++ + +LQK + E L EQ+L D+ R+ QER
Sbjct: 1496 DRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQD 1555
Query: 118 ---FEEAKNTLCLIQNKLKEEEKRLLKSGSND 146
F+ + L L + K++EE RL ++ S D
Sbjct: 1556 ITRFQNSLKELQLQKQKVEEELNRLKRTASED 1587
Score = 35.8 bits (81), Expect = 0.035
Identities = 26/137 (18%), Positives = 65/137 (47%), Gaps = 3/137 (2%)
Query: 6 IARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRL 65
++ L+ E K+ I+ + +++ +D + + L+ ++K + E + + +L
Sbjct: 1017 LSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKL 1076
Query: 66 ETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRME---QERFEEAK 122
+L+ ++ + + ++ L K Y E + +T L ++ED R ++RF++ K
Sbjct: 1077 ASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQK 1136
Query: 123 NTLCLIQNKLKEEEKRL 139
N +Q + E++ L
Sbjct: 1137 NDYDQLQKARQCEKENL 1153
Score = 34.7 bits (78), Expect = 0.079
Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 17/151 (11%)
Query: 13 NETEKVMRIAIKEIL-------TQVQKTKDLLNNVA----SDEANLEAKIEKRKLELERN 61
NE KV +EI+ T++ TK ++ + D + A+I+ E
Sbjct: 1346 NELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSL 1405
Query: 62 RKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEA 121
+ ++ L++ + + EE++Q+Q T E Q LE +L +M E
Sbjct: 1406 SEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRY 1465
Query: 122 KNTL----CLIQNKLKEEE--KRLLKSGSND 146
K +L IQ+K KE E K+L+ +ND
Sbjct: 1466 KQSLDDAAKTIQDKNKEIERLKQLIDKETND 1496
Score = 34.7 bits (78), Expect = 0.079
Identities = 35/136 (25%), Positives = 69/136 (50%), Gaps = 9/136 (6%)
Query: 3 TEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANL-EAKIEKRKLELERN 61
TE I + L++ E E E ++Q + KD ++ + +L E +++K+K+E E N
Sbjct: 1522 TETINK-LKVQEQELTRLRIDYERVSQERTVKD--QDITRFQNSLKELQLQKQKVEEELN 1578
Query: 62 RKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEA 121
R L+ S C + +K EEEL+ + E+ +T L QQLE +++ ++
Sbjct: 1579 R--LKRTASEDSC---KRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDL 1633
Query: 122 KNTLCLIQNKLKEEEK 137
+ ++ L+E+++
Sbjct: 1634 RQQRDVLDGHLREKQR 1649
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 45.8 bits (107), Expect = 3e-05
Identities = 41/213 (19%), Positives = 98/213 (46%), Gaps = 20/213 (9%)
Query: 25 EILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEE 84
+++T++ ++ +++S +L+ +E + E+ K +E+L+S + E+++ +
Sbjct: 1550 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHK 1609
Query: 85 ELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGS 144
ELQK+Y+ L+ ++N++ ++++ ++ +E L + KE EK+L ++
Sbjct: 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAE- 1668
Query: 145 NDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQ-----------GRPGKRIVGTMQGG 193
QE +E ++ + K Q +E+ + G K + T+
Sbjct: 1669 --------QEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSS 1720
Query: 194 DSDDNEDSEESEIDMEDDDDEDDDLEDESISLS 226
++ E+ E +++ E + L E SLS
Sbjct: 1721 NASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1753
Score = 36.2 bits (82), Expect = 0.027
Identities = 51/268 (19%), Positives = 109/268 (40%), Gaps = 42/268 (15%)
Query: 17 KVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFM 76
K ++ + ++ ++K K+ N+ EA I+ K E+ L+ + +
Sbjct: 2315 KSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLH 2374
Query: 77 DEYEKTEE------------------ELQKQYDTYLEKFQNLTYLEQQ----LEDHHRME 114
+E E+ EL++Q+D +++ +NL E++ LE+ ++
Sbjct: 2375 EEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKA 2434
Query: 115 QERFEEAKNTLCLIQNKLKEEEKRL---LKSGSNDDSDIDIQEDDESDSELEERR----L 167
++ + TL I+ + +++ +L +KS S+ +D D D +LEER L
Sbjct: 2435 VDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDY--QQLEERHLSIIL 2492
Query: 168 PKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDM----ED-------DDDEDD 216
K Q E + K + ++ D N ++ + + ++ ED D +
Sbjct: 2493 EKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK 2552
Query: 217 DLEDESISLSPTKPNRRVRKSEPLDESD 244
L + + + N+ + E L ES+
Sbjct: 2553 QLLEVQLQQNKELENKYAKLEEKLKESE 2580
Score = 35.4 bits (80), Expect = 0.046
Identities = 42/208 (20%), Positives = 91/208 (43%), Gaps = 14/208 (6%)
Query: 18 VMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMD 77
V++ ++++ +++ K ++ + D+ E+K + E++ +K +TLQ +
Sbjct: 2235 VLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQT---EVQLQQKVCDTLQGENKELLS 2291
Query: 78 EYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEK 137
+ E+T + + L L+ QL D E+ +E K L + ++++E
Sbjct: 2292 QLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN-SLEKCKEQKGNL---EGIIRQQEA 2347
Query: 138 RLLKSG-SNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSD 196
+ S S + + D+Q E S L E K Q + +L GK + +
Sbjct: 2348 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLL----SGKEEAIQVAIAELR 2403
Query: 197 DNEDSEESEID--MEDDDDEDDDLEDES 222
D E E++ + +++E+ LE+E+
Sbjct: 2404 QQHDKEIKELENLLSQEEEENIVLEEEN 2431
Score = 34.7 bits (78), Expect = 0.079
Identities = 43/166 (25%), Positives = 75/166 (45%), Gaps = 6/166 (3%)
Query: 4 EAIARPLEINETEKVMRIAI-KEILTQ-VQKTKDLLNNVASDEANLEAKIEKRKLELERN 61
E + LE +TE + I KE L Q V+ K +AS + L+ + L N
Sbjct: 2039 ERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADN 2098
Query: 62 RKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEA 121
K + LQS + + ++ +E+L+++ + EK Q+ D R E+ EE
Sbjct: 2099 LKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEE- 2157
Query: 122 KNTLCLIQNKLKEEEKRLLKSGSNDDSDI-DIQEDDESDSELEERR 166
T+ IQ L +++K + + N DS + + +S S L++ R
Sbjct: 2158 --TIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDR 2201
Score = 34.3 bits (77), Expect = 0.10
Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 14/118 (11%)
Query: 47 LEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQ 106
LE KI + E E+ +K+L+ + R + + ++ E L+++ L+QQ
Sbjct: 1162 LEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREE-------------LKQQ 1208
Query: 107 LEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEE 164
+D++R+ QE+F+E I ++L++ + ++ +S D QE S LEE
Sbjct: 1209 KDDYNRL-QEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEE 1265
Score = 31.6 bits (70), Expect = 0.67
Identities = 40/205 (19%), Positives = 86/205 (41%), Gaps = 24/205 (11%)
Query: 35 DLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYL 94
D +NN L+ +I + E ++N++ +TL++ + + + + EL+
Sbjct: 1833 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELK----MLQ 1888
Query: 95 EKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDI-DIQ 153
E+ + L QQ+++ + E A+ ++ +L + L S N D+ D Q
Sbjct: 1889 EEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQ 1948
Query: 154 EDDE-------------SDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNED 200
+E S+ E E+++L K +T +E ++ K + +QG +
Sbjct: 1949 IKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR----KEYLEKIQGAQKEPGNK 2004
Query: 201 SEESEID--MEDDDDEDDDLEDESI 223
S E+ +++ E L+ + I
Sbjct: 2005 SHAKELQELLKEKQQEVKQLQKDCI 2029
Score = 29.6 bits (65), Expect = 2.5
Identities = 35/174 (20%), Positives = 73/174 (41%), Gaps = 34/174 (19%)
Query: 1 MRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELER 60
++ A A+ +N+ + M+ +L ++++ L+ E +IEK K +L+
Sbjct: 96 LKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQE 155
Query: 61 NRKRLETLQ-----------SVRPCFMDEYEKTEEELQ--KQYDTYLEKFQNLTYLEQQL 107
+ + TLQ + M+E+ +++LQ +++ + L+ + T EQ
Sbjct: 156 KEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAA 215
Query: 108 EDHHRMEQERFE---------------------EAKNTLCLIQNKLKEEEKRLL 140
+ R + RFE E + L ++Q KL+E E+ L+
Sbjct: 216 QQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLV 269
Score = 29.6 bits (65), Expect = 2.5
Identities = 27/129 (20%), Positives = 59/129 (45%), Gaps = 12/129 (9%)
Query: 46 NLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ 105
+L+++++ ++ E+ +R+ + S + E E+ K LEK +++ L+Q
Sbjct: 835 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQ 894
Query: 106 QLEDHHRMEQE----------RFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQED 155
+E+ + E + E K +L + LKE+ L S + + ++ED
Sbjct: 895 TIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLN--LLSRAEEAKKEQVEED 952
Query: 156 DESDSELEE 164
+E S L++
Sbjct: 953 NEVSSGLKQ 961
Score = 28.9 bits (63), Expect = 4.3
Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 20/158 (12%)
Query: 2 RTEAIARPLEINETEKVMRIAIKE---ILTQVQKTKDLLNNVAS--DEANLEAKIEKRKL 56
R +AR L E E+ + + KE + Q+Q ++++ + D AN E KRK
Sbjct: 2704 RVAELARDLV--EMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2761
Query: 57 ELER------------NRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLE 104
+ NR+R L E + L+K L K + L +L
Sbjct: 2762 DASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLS 2821
Query: 105 QQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 142
QLED + Q F +A +L ++ L E ++ KS
Sbjct: 2822 SQLEDSYNQVQS-FSKAMASLQNERDHLWNELEKFRKS 2858
Score = 27.7 bits (60), Expect = 9.6
Identities = 32/176 (18%), Positives = 82/176 (46%), Gaps = 7/176 (3%)
Query: 49 AKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLE 108
A+I+ + E+E + LE S + + + +LQ+Q + + ++L + + E
Sbjct: 1305 AQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAE 1364
Query: 109 DHHRMEQERFEEAKNTLCLIQN--KLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERR 166
H Q++ E ++ + +++ +L+ + L K S + D+ S+ +E
Sbjct: 1365 VHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSE---KEAA 1421
Query: 167 LPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDES 222
L K QT E++ Q K + ++ + +E ++ ++++ + + +++ +ES
Sbjct: 1422 LTKIQT--EIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEES 1475
>gi|222537714 taxilin beta [Homo sapiens]
Length = 684
Score = 45.4 bits (106), Expect = 4e-05
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 13/165 (7%)
Query: 7 ARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRL- 65
A L+ + TE+ +++ Q+QK KD L S +K+E EL+R+ K L
Sbjct: 170 AELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLK 229
Query: 66 -ETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNT 124
E LQ R E E+ +E+ + + L Q +EQQ E + ++ QE E A+
Sbjct: 230 EEALQRAR-----EEEEKRKEITSHFQSTLTDIQG--QIEQQSERNMKLCQENTELAEKL 282
Query: 125 LCLI-QNKLKEEE-KRLLKSGSNDDSDID--IQEDDESDSELEER 165
+I Q +L+EE ++ K +D +++ E E EER
Sbjct: 283 KSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEER 327
Score = 30.4 bits (67), Expect = 1.5
Identities = 27/157 (17%), Positives = 71/157 (45%), Gaps = 15/157 (9%)
Query: 2 RTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERN 61
+ E++ R L+ + + A++ + +K K++ ++ S +++ +IE++ ERN
Sbjct: 213 KLESLCRELQ-RHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQS---ERN 268
Query: 62 RKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEA 121
K + E + E+L+ D Y + ++L + + E ++ + E+A
Sbjct: 269 MKLCQ-----------ENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQA 317
Query: 122 KNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDES 158
+ + + + K E++ LL + + ++ E+
Sbjct: 318 QEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQET 354
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 45.4 bits (106), Expect = 4e-05
Identities = 56/206 (27%), Positives = 100/206 (48%), Gaps = 25/206 (12%)
Query: 7 ARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLE 66
A LE E+ +R A + +L + ++ K+LL + +++ +IE + L++ +
Sbjct: 205 ANALEEQLKEQELR-ACEMVLEETRRQKELLCKMEREKS---IEIENLQTRLQQLDEENS 260
Query: 67 TLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTY-LEQQLEDHHRM------EQERFE 119
L+S PC E+ EEE QK L++ ++LT L ++ E+ RM E+ +F+
Sbjct: 261 ELRSCTPCLKANIERLEEEKQK----LLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQ 316
Query: 120 EAKN-TLCLIQNKLKE-EEKRLLKSGSND----DSDIDIQE----DDESDSELEERRLPK 169
K T LI++ K+ E +LLK + S + +QE ES+ E E RRL +
Sbjct: 317 RDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQ 376
Query: 170 PQTAMEMLMQGRPGKRIVGTMQGGDS 195
++ + G+ I ++QG S
Sbjct: 377 DNRNLKEQNEELNGQIITLSIQGAKS 402
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 45.4 bits (106), Expect = 4e-05
Identities = 56/206 (27%), Positives = 100/206 (48%), Gaps = 25/206 (12%)
Query: 7 ARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLE 66
A LE E+ +R A + +L + ++ K+LL + +++ +IE + L++ +
Sbjct: 501 ANALEEQLKEQELR-ACEMVLEETRRQKELLCKMEREKS---IEIENLQTRLQQLDEENS 556
Query: 67 TLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTY-LEQQLEDHHRM------EQERFE 119
L+S PC E+ EEE QK L++ ++LT L ++ E+ RM E+ +F+
Sbjct: 557 ELRSCTPCLKANIERLEEEKQK----LLDEIESLTLRLSEEQENKRRMGDRLSHERHQFQ 612
Query: 120 EAKN-TLCLIQNKLKE-EEKRLLKSGSND----DSDIDIQE----DDESDSELEERRLPK 169
K T LI++ K+ E +LLK + S + +QE ES+ E E RRL +
Sbjct: 613 RDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSMGLQEYHSRARESELEQEVRRLKQ 672
Query: 170 PQTAMEMLMQGRPGKRIVGTMQGGDS 195
++ + G+ I ++QG S
Sbjct: 673 DNRNLKEQNEELNGQIITLSIQGAKS 698
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 45.4 bits (106), Expect = 4e-05
Identities = 53/234 (22%), Positives = 108/234 (46%), Gaps = 20/234 (8%)
Query: 11 EINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ 69
EIN EK +R+ + I +V + LN++ ++ A L +K+EK K ER +E+L
Sbjct: 472 EINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLH 531
Query: 70 SVRPCFMDEY----EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTL 125
S ++EY E+ + EL + + + + QL D + + E+ +A+
Sbjct: 532 SNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKF 591
Query: 126 CLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDDESDSEL----------EERRLPKPQTAM 174
++ KL+E L K+ + + +D+++ E+ E + + K ++
Sbjct: 592 NTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSE 651
Query: 175 EMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLEDESISL 225
E + Q R + ++ Q D+ D++E I++ D + ++D LE+ + L
Sbjct: 652 ERIRQ-RELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKEL 704
Score = 30.0 bits (66), Expect = 1.9
Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 14/102 (13%)
Query: 6 IARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLEL------- 58
+A+ E+ E + ++E +++K K +L NL+ +EK +EL
Sbjct: 875 LAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKV---LNLKTHMEKDMVELGKVQEYK 931
Query: 59 ----ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEK 96
ER + +E L+ + EYEK E+L K L+K
Sbjct: 932 SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK 973
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 45.4 bits (106), Expect = 4e-05
Identities = 53/234 (22%), Positives = 108/234 (46%), Gaps = 20/234 (8%)
Query: 11 EINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ 69
EIN EK +R+ + I +V + LN++ ++ A L +K+EK K ER +E+L
Sbjct: 501 EINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLH 560
Query: 70 SVRPCFMDEY----EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTL 125
S ++EY E+ + EL + + + + QL D + + E+ +A+
Sbjct: 561 SNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKF 620
Query: 126 CLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDDESDSEL----------EERRLPKPQTAM 174
++ KL+E L K+ + + +D+++ E+ E + + K ++
Sbjct: 621 NTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSE 680
Query: 175 EMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLEDESISL 225
E + Q R + ++ Q D+ D++E I++ D + ++D LE+ + L
Sbjct: 681 ERIRQ-RELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKEL 733
Score = 30.0 bits (66), Expect = 1.9
Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 14/102 (13%)
Query: 6 IARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLEL------- 58
+A+ E+ E + ++E +++K K +L NL+ +EK +EL
Sbjct: 904 LAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKV---LNLKTHMEKDMVELGKVQEYK 960
Query: 59 ----ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEK 96
ER + +E L+ + EYEK E+L K L+K
Sbjct: 961 SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK 1002
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 45.4 bits (106), Expect = 4e-05
Identities = 53/234 (22%), Positives = 108/234 (46%), Gaps = 20/234 (8%)
Query: 11 EINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ 69
EIN EK +R+ + I +V + LN++ ++ A L +K+EK K ER +E+L
Sbjct: 501 EINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLH 560
Query: 70 SVRPCFMDEY----EKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTL 125
S ++EY E+ + EL + + + + QL D + + E+ +A+
Sbjct: 561 SNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKF 620
Query: 126 CLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDDESDSEL----------EERRLPKPQTAM 174
++ KL+E L K+ + + +D+++ E+ E + + K ++
Sbjct: 621 NTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSE 680
Query: 175 EMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLEDESISL 225
E + Q R + ++ Q D+ D++E I++ D + ++D LE+ + L
Sbjct: 681 ERIRQ-RELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKEL 733
Score = 30.0 bits (66), Expect = 1.9
Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 14/102 (13%)
Query: 6 IARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLEL------- 58
+A+ E+ E + ++E +++K K +L NL+ +EK +EL
Sbjct: 904 LAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKV---LNLKTHMEKDMVELGKVQEYK 960
Query: 59 ----ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEK 96
ER + +E L+ + EYEK E+L K L+K
Sbjct: 961 SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK 1002
>gi|217035164 coiled-coil domain containing 27 [Homo sapiens]
Length = 656
Score = 45.4 bits (106), Expect = 4e-05
Identities = 37/155 (23%), Positives = 69/155 (44%), Gaps = 11/155 (7%)
Query: 11 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAK--IEKRKLELERNRKRLETL 68
+IN + ++ ++E Q+Q D +N+ D+ + E IEK L + LE
Sbjct: 459 KINTENETLQKELRERRQQLQAMTDKFSNLREDKKHQEMMGLIEKDNQLLRQQVSELERK 518
Query: 69 QSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLI 128
+ R C + E + +LQ+Q + Q L++ L+ M Q+ + + L
Sbjct: 519 LTKRDCVISELDTKVSQLQEQVELDQNHLQRWKQLQEDLQSKKEMIQQAEQHTRVALESS 578
Query: 129 QNKLKEEEKRLL---------KSGSNDDSDIDIQE 154
Q++L+ +++ KS +N+ SD DI E
Sbjct: 579 QSRLERLRNKIIQATFSISGTKSLANEISDNDILE 613
Score = 29.3 bits (64), Expect = 3.3
Identities = 45/201 (22%), Positives = 77/201 (38%), Gaps = 29/201 (14%)
Query: 60 RNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLE---QQLEDHHRMEQE 116
R R++ +TL V + + + EK L+ LE Q+ ++ + QE
Sbjct: 201 RKRRKSQTLSPVTSSSVASQSCLRKRMPWYLSVIHEKDHCLSELEIQVQKKDEEILLLQE 260
Query: 117 RFEEAKNTL-CLIQNK------------------LKEEEKRLLKSGSNDDSDID----IQ 153
E K L CL++ K LK LLK+ S + ++ +Q
Sbjct: 261 EREALKMQLKCLLKGKGQETSMSPGRREQLSDASLKLGRLSLLKAFSRHEEELQHWWQMQ 320
Query: 154 EDDESDSELEERRLPKPQTAMEMLMQGRP-GKRIVGTMQGGDSDDNEDSEESEIDMEDDD 212
E+ + +E L + + ++G P G G G + E SE + E++
Sbjct: 321 EESAAPERGKEPDLGGGEE--DEGLEGEPDGVEDTGAWGGVSQMGSVHEEGSEEEEEEEG 378
Query: 213 DEDDDLEDESISLSPTKPNRR 233
D D+D E+ + P RR
Sbjct: 379 DRDEDSEERELPEEEEIPRRR 399
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 45.1 bits (105), Expect = 6e-05
Identities = 40/161 (24%), Positives = 75/161 (46%), Gaps = 12/161 (7%)
Query: 11 EINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQS 70
E N K + +++ +V+ + L E L + E+ + + ER R++ E L
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCE 224
Query: 71 VRPCFMDEYEKT---EEELQKQYDTYLEKFQNLTYLEQQL---EDHHRMEQERFEEAKNT 124
++ E+ EE L +Q + E + L E++L E+ R ++ER E +
Sbjct: 225 QEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEER 284
Query: 125 LCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEER 165
LC + +L+E+E+RL + + ++E +E E EER
Sbjct: 285 LCEQEERLREQEERLC------EQEERLREQEERLCEQEER 319
Score = 42.7 bits (99), Expect = 3e-04
Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 12/173 (6%)
Query: 12 INETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETL--Q 69
+ E E+ +R + + Q ++ + + E L + E+ + ER R+ E L Q
Sbjct: 201 LREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQ 260
Query: 70 SVRPCFMDE-YEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLI 128
R C +E + EE L +Q + E+ + L E++L + ++ER E + LC
Sbjct: 261 EERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCE----QEERLREQEERLCEQ 316
Query: 129 QNKLKEEEKRLLKSGSNDDSDIDIQE-----DDESDSELEERRLPKPQTAMEM 176
+ +L+E+E+RL + + ++E + E E +ER L + + E+
Sbjct: 317 EERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEV 369
Score = 34.7 bits (78), Expect = 0.079
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 10/102 (9%)
Query: 64 RLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKN 123
++E LQ E E +LQ + +E Q L+ L ++ E+ R ++ER E +
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAE----VENNQMLSLLNRRQEERLREQEERLREQEE 213
Query: 124 TLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEER 165
L + +L E+E+RL + + ++E +E E EER
Sbjct: 214 RLREQEERLCEQEERL------REQEERLREQEERLCEQEER 249
Score = 28.5 bits (62), Expect = 5.6
Identities = 28/153 (18%), Positives = 67/153 (43%), Gaps = 2/153 (1%)
Query: 14 ETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRP 73
E E+ +R + + Q ++ ++ + E L + E+R E E+ + L+ V
Sbjct: 287 EQEERLREQEERLCEQEERLREQEERLCEQEERLREQ-EERLCEQEKLPGQERLLEEVEK 345
Query: 74 CFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLK 133
E + E+E + + LE+ + L E+ + R+ Q+ + L ++ L+
Sbjct: 346 LLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLE 405
Query: 134 EEEKRLLKSGSNDDSDI-DIQEDDESDSELEER 165
+ L + + S ++ +++S +LE++
Sbjct: 406 LGWEALYEQRAEPRSGFEELNNENKSTLQLEQQ 438
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 44.7 bits (104), Expect = 8e-05
Identities = 43/220 (19%), Positives = 99/220 (45%), Gaps = 21/220 (9%)
Query: 40 VASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQN 99
+ + + A E R++E ++E + E++ E QK + Q
Sbjct: 256 IEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQR 315
Query: 100 LTYLEQQLEDHHRME-QERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDES 158
LE+ H+ +E +E EE + + ++ + ++E++ + + ++ ++E+ E
Sbjct: 316 EEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQE---EEEQKQEMEVKMEEETEV 372
Query: 159 DSELEERRLPKPQTAMEMLMQGRPGKRIV--------GTMQGGDSDDNEDSEESEIDMED 210
E E+++ +P+ M++L K ++ ++ + +NE S+E E +ME
Sbjct: 373 -RESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEF 431
Query: 211 DDDEDDDLEDESISLSPTKPNRRV----RKSEPLDESDND 246
+ + D + + SLSP K N ++SE +E +++
Sbjct: 432 EIEPDKECK----SLSPGKENVSALDMEKESEEKEEKESE 467
Score = 34.7 bits (78), Expect = 0.079
Identities = 33/155 (21%), Positives = 67/155 (43%), Gaps = 13/155 (8%)
Query: 29 QVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQK 88
++++T + N+V +EA E + E + + +++ E Q E E E +K
Sbjct: 318 ELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEK 377
Query: 89 QYDTYLEKFQNLTYLEQQLE----DHHRMEQERFEEAKNTLCLIQNKLKEE--------- 135
Q D+ E+ ++ + + ++ D ME R E + + +L+ E
Sbjct: 378 QQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDK 437
Query: 136 EKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKP 170
E + L G + S +D++++ E E E P+P
Sbjct: 438 ECKSLSPGKENVSALDMEKESEEKEEKESEPQPEP 472
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 44.7 bits (104), Expect = 8e-05
Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 8/95 (8%)
Query: 160 SELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSD-----DNEDS---EESEIDMEDD 211
S+ +E+ + ++ P K +V +G DSD D+EDS EE + + ED+
Sbjct: 561 SQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDE 620
Query: 212 DDEDDDLEDESISLSPTKPNRRVRKSEPLDESDND 246
+D++DD D+S S S + SE D+ D D
Sbjct: 621 EDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKD 655
Score = 39.7 bits (91), Expect = 0.002
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 18/92 (19%)
Query: 144 SNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEE 203
SN+D + D +E+DE D E +E + ++ D E SEE
Sbjct: 607 SNEDEEEDDEEEDEEDDEDDESDDSQSES------------------DSNSESDTEGSEE 648
Query: 204 SEIDMEDDDDEDDDLEDESISLSPTKPNRRVR 235
+ D +D D+ D D E E S+ K V+
Sbjct: 649 EDDDDKDQDESDSDTEGEKTSMKLNKTTSSVK 680
Score = 34.7 bits (78), Expect = 0.079
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 7/54 (12%)
Query: 191 QGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESD 244
+GGDSD ++D ++ D D+DDED++ +++ K ++ E DE D
Sbjct: 1293 KGGDSDYDDDDDDDSDDQGDEDDEDEEDKED-------KKGKKTDICEDEDEGD 1339
Score = 34.3 bits (77), Expect = 0.10
Identities = 24/107 (22%), Positives = 48/107 (44%), Gaps = 10/107 (9%)
Query: 141 KSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNED 200
KS S+ + ++ + L+ R ++ + +P K+ + + DSD
Sbjct: 201 KSTSSGGGNRKCNQEQSKNQPLDAR--------VDKIKDKKPRKKAMESSSNSDSDSGTS 252
Query: 201 SEESE--IDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDN 245
S+ S I D DD ++D E+E S+ ++ + +SE +S+N
Sbjct: 253 SDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299
Score = 30.0 bits (66), Expect = 1.9
Identities = 12/37 (32%), Positives = 22/37 (59%)
Query: 180 GRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDD 216
GR +R G D DD++ ++ + D ED++D++D
Sbjct: 1287 GRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKED 1323
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 44.7 bits (104), Expect = 8e-05
Identities = 47/187 (25%), Positives = 86/187 (45%), Gaps = 17/187 (9%)
Query: 2 RTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL----- 56
R E + + L+ E + M+ K+ + Q D A +E E K +K+
Sbjct: 574 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 633
Query: 57 ELERNRKRLETLQSVRPCFMDEYEKTEEE-LQKQYDTYLEKFQNLTYLEQQLE--DHHRM 113
E+E RK+ E + +R +E E+ +E LQK+ + E+ + ++ E + R
Sbjct: 634 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 693
Query: 114 EQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEER----RLPK 169
EQER E+ + + + +E+E++L + + QE +++ EL+ER RL K
Sbjct: 694 EQERREQERREQERREQERREQERQLAEQERRRE-----QERLQAERELQEREKALRLQK 748
Query: 170 PQTAMEM 176
Q E+
Sbjct: 749 EQLQREL 755
Score = 37.7 bits (86), Expect = 0.009
Identities = 48/257 (18%), Positives = 107/257 (41%), Gaps = 31/257 (12%)
Query: 17 KVMRIAIKEILTQVQKTKDLLNNVASDEA--------NLEAKIEKRKLELERNRKRLETL 68
KV+R ++ L VQ+ + L+ ++ + N +++ + +E+ R+RLE L
Sbjct: 487 KVVR-PLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENL 545
Query: 69 QSVRPCFMDEYEKTEEELQKQY-DTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCL 127
+ +K EE+ +++ + L++ + L + Q E +M++E+ ++ +
Sbjct: 546 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 605
Query: 128 IQNKLKE-------EEKRLLKSGSNDDSDIDIQEDDESDS--------ELEERR-----L 167
I K ++ EEK K+ + +++ + E ++ E EERR
Sbjct: 606 IDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 665
Query: 168 PKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSP 227
K + E L + KR+ + + + E E+ + E + E + E +
Sbjct: 666 KKKEEEQERLRKAAEAKRL-AEQREQERREQERREQERREQERREQERREQERQLAEQER 724
Query: 228 TKPNRRVRKSEPLDESD 244
+ R++ L E +
Sbjct: 725 RREQERLQAERELQERE 741
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 44.7 bits (104), Expect = 8e-05
Identities = 47/187 (25%), Positives = 86/187 (45%), Gaps = 17/187 (9%)
Query: 2 RTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKL----- 56
R E + + L+ E + M+ K+ + Q D A +E E K +K+
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
Query: 57 ELERNRKRLETLQSVRPCFMDEYEKTEEE-LQKQYDTYLEKFQNLTYLEQQLE--DHHRM 113
E+E RK+ E + +R +E E+ +E LQK+ + E+ + ++ E + R
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689
Query: 114 EQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEER----RLPK 169
EQER E+ + + + +E+E++L + + QE +++ EL+ER RL K
Sbjct: 690 EQERREQERREQERREQERREQERQLAEQERRRE-----QERLQAERELQEREKALRLQK 744
Query: 170 PQTAMEM 176
Q E+
Sbjct: 745 EQLQREL 751
Score = 39.3 bits (90), Expect = 0.003
Identities = 49/253 (19%), Positives = 108/253 (42%), Gaps = 27/253 (10%)
Query: 17 KVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEK----RKLELERNRKRLETLQSVR 72
KV+R ++ L VQ+ + L+ ++ + +++ I++ R E+ R+RLE L+
Sbjct: 487 KVVR-PLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKE 545
Query: 73 PCFMDEYEKTEEELQKQYDTY-LEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNK 131
+K EE+ +++ + L++ + L + Q E +M++E+ ++ + I K
Sbjct: 546 EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 605
Query: 132 LKE-------EEKRLLKSGSNDDSDIDIQEDDESDS--------ELEERR-----LPKPQ 171
++ EEK K+ + +++ + E ++ E EERR K +
Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665
Query: 172 TAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPN 231
E L + KR+ + + + E E+ + E + E + E + +
Sbjct: 666 EEQERLRKAAEAKRL-AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724
Query: 232 RRVRKSEPLDESD 244
R++ L E +
Sbjct: 725 ERLQAERELQERE 737
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 44.3 bits (103), Expect = 1e-04
Identities = 30/133 (22%), Positives = 62/133 (46%), Gaps = 17/133 (12%)
Query: 105 QQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEE 164
Q+++D +M ++R E ++ + N+ +E + G D IQ DE ++ +E
Sbjct: 186 QKMDDMKKMRRQRMRELEDLG--VFNETEESNLNMYTRGKQKD----IQRTDEETTDNQE 239
Query: 165 RRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESIS 224
+ + + + G+ +D+ED ++ + D +DDDDEDD+ E++
Sbjct: 240 GSVESSEEGEDQEHE-----------DDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEE 288
Query: 225 LSPTKPNRRVRKS 237
+ + R RK+
Sbjct: 289 ENQKRYYLRQRKA 301
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/235 (22%), Positives = 109/235 (46%), Gaps = 22/235 (9%)
Query: 11 EINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ 69
EIN EK +R+ K I V + LN++ ++ A L +++EK K ER +E+L
Sbjct: 471 EINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLH 530
Query: 70 SVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ------QLEDHHRMEQERFEEAKN 123
S ++EY + E +K + L + +++ E+ QL D + + E+ +A+
Sbjct: 531 SSLATAINEYNEIVE--RKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARV 588
Query: 124 TLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDD---------ESDSELEERRLPKPQTA 173
++ KL+E L K+ + +D+++ + E +E + Q +
Sbjct: 589 KFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNS 648
Query: 174 MEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLEDESISL 225
+E ++ + + ++ Q D+ D++E I++ D + ++D LE+ + L
Sbjct: 649 LEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKEL 703
Score = 31.6 bits (70), Expect = 0.67
Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 26/156 (16%)
Query: 6 IARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLEL------- 58
+A+ E+ E + ++E +++K K +L + NL+ +EK +EL
Sbjct: 874 LAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEE---EVLNLKTHMEKDMVELGKLQEYK 930
Query: 59 ----ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLE------ 108
ER + +E L+ + EYEK E+L K L+K + LT + + +
Sbjct: 931 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK-KELTLKDVECKFSKMKT 989
Query: 109 --DHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 142
+ E E F+EA N + K+L+KS
Sbjct: 990 AYEEVTTELEEFKEAFAGAVKANNSM---SKKLMKS 1022
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/235 (22%), Positives = 109/235 (46%), Gaps = 22/235 (9%)
Query: 11 EINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ 69
EIN EK +R+ K I V + LN++ ++ A L +++EK K ER +E+L
Sbjct: 364 EINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLH 423
Query: 70 SVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ------QLEDHHRMEQERFEEAKN 123
S ++EY + E +K + L + +++ E+ QL D + + E+ +A+
Sbjct: 424 SSLATAINEYNEIVE--RKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARV 481
Query: 124 TLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDD---------ESDSELEERRLPKPQTA 173
++ KL+E L K+ + +D+++ + E +E + Q +
Sbjct: 482 KFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNS 541
Query: 174 MEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLEDESISL 225
+E ++ + + ++ Q D+ D++E I++ D + ++D LE+ + L
Sbjct: 542 LEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKEL 596
Score = 31.6 bits (70), Expect = 0.67
Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 26/156 (16%)
Query: 6 IARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLEL------- 58
+A+ E+ E + ++E +++K K +L + NL+ +EK +EL
Sbjct: 767 LAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEE---EVLNLKTHMEKDMVELGKLQEYK 823
Query: 59 ----ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLE------ 108
ER + +E L+ + EYEK E+L K L+K + LT + + +
Sbjct: 824 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK-KELTLKDVECKFSKMKT 882
Query: 109 --DHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 142
+ E E F+EA N + K+L+KS
Sbjct: 883 AYEEVTTELEEFKEAFAGAVKANNSM---SKKLMKS 915
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/235 (22%), Positives = 109/235 (46%), Gaps = 22/235 (9%)
Query: 11 EINET-EKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQ 69
EIN EK +R+ K I V + LN++ ++ A L +++EK K ER +E+L
Sbjct: 471 EINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLH 530
Query: 70 SVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQ------QLEDHHRMEQERFEEAKN 123
S ++EY + E +K + L + +++ E+ QL D + + E+ +A+
Sbjct: 531 SSLATAINEYNEIVE--RKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARV 588
Query: 124 TLCLIQNKLKEEEKRLL-KSGSNDDSDIDIQEDD---------ESDSELEERRLPKPQTA 173
++ KL+E L K+ + +D+++ + E +E + Q +
Sbjct: 589 KFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNS 648
Query: 174 MEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDD---DDEDDDLEDESISL 225
+E ++ + + ++ Q D+ D++E I++ D + ++D LE+ + L
Sbjct: 649 LEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKEL 703
Score = 31.6 bits (70), Expect = 0.67
Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 26/156 (16%)
Query: 6 IARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLEL------- 58
+A+ E+ E + ++E +++K K +L + NL+ +EK +EL
Sbjct: 874 LAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEE---EVLNLKTHMEKDMVELGKLQEYK 930
Query: 59 ----ERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLE------ 108
ER + +E L+ + EYEK E+L K L+K + LT + + +
Sbjct: 931 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKK-KELTLKDVECKFSKMKT 989
Query: 109 --DHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKS 142
+ E E F+EA N + K+L+KS
Sbjct: 990 AYEEVTTELEEFKEAFAGAVKANNSM---SKKLMKS 1022
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 44.3 bits (103), Expect = 1e-04
Identities = 53/237 (22%), Positives = 99/237 (41%), Gaps = 40/237 (16%)
Query: 12 INETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLET-LQS 70
+NE EK IKE+ ++++ K + + + +N LERN R+E + S
Sbjct: 200 LNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASN-----------LERNDLRIEDGISS 248
Query: 71 VRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQN 130
P ++E +K YL++ +N T + + E + E + ++ + ++
Sbjct: 249 TLP--------SKESRRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKT 300
Query: 131 KLK-----EEEKRLLKSGSNDDSDIDIQEDDESD---SELEERRLP-KPQTAMEMLMQGR 181
++K EEE + +KS +ND D + E +++ S+LEE +L K Q +E
Sbjct: 301 QIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELEN----- 355
Query: 182 PGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSE 238
G ++G D+ + E + + LSP R+R E
Sbjct: 356 ------GEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNRE 406
Score = 32.0 bits (71), Expect = 0.51
Identities = 47/250 (18%), Positives = 108/250 (43%), Gaps = 32/250 (12%)
Query: 16 EKVMRIAIKEILTQVQKTKDL---LNNVASDEANLEAKIEKRKLELERNRKRLETLQSVR 72
++V+RI K+ ++++ +DL + +E NL ++ K E+ER +KR+ L+ +
Sbjct: 70 QRVLRIEGKD--EEIKRAEDLCRLMKEKLEEEENLTREL---KSEIERLQKRMAELEKLE 124
Query: 73 PCF-------------MDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFE 119
F ++E +++ + + K + L E +L+ + E
Sbjct: 125 EAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELE 184
Query: 120 EAKN-TLCLI------QNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQT 172
+ K+ TL + K KE EK + + + + + D ++ ER + +
Sbjct: 185 KLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIED 244
Query: 173 AMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNR 232
+ + + +R G + +NE +SE + ++ + ED+ ++D + + K
Sbjct: 245 GISSTLPSKESRR-KGGLDYLKQVENETRNKSE-NEKNRNQEDNKVKDLNQEIEKLK--T 300
Query: 233 RVRKSEPLDE 242
+++ E L+E
Sbjct: 301 QIKHFESLEE 310
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 44.3 bits (103), Expect = 1e-04
Identities = 53/237 (22%), Positives = 99/237 (41%), Gaps = 40/237 (16%)
Query: 12 INETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLET-LQS 70
+NE EK IKE+ ++++ K + + + +N LERN R+E + S
Sbjct: 200 LNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASN-----------LERNDLRIEDGISS 248
Query: 71 VRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQN 130
P ++E +K YL++ +N T + + E + E + ++ + ++
Sbjct: 249 TLP--------SKESRRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKT 300
Query: 131 KLK-----EEEKRLLKSGSNDDSDIDIQEDDESD---SELEERRLP-KPQTAMEMLMQGR 181
++K EEE + +KS +ND D + E +++ S+LEE +L K Q +E
Sbjct: 301 QIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELEN----- 355
Query: 182 PGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSE 238
G ++G D+ + E + + LSP R+R E
Sbjct: 356 ------GEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNRE 406
Score = 32.0 bits (71), Expect = 0.51
Identities = 47/250 (18%), Positives = 108/250 (43%), Gaps = 32/250 (12%)
Query: 16 EKVMRIAIKEILTQVQKTKDL---LNNVASDEANLEAKIEKRKLELERNRKRLETLQSVR 72
++V+RI K+ ++++ +DL + +E NL ++ K E+ER +KR+ L+ +
Sbjct: 70 QRVLRIEGKD--EEIKRAEDLCRLMKEKLEEEENLTREL---KSEIERLQKRMAELEKLE 124
Query: 73 PCF-------------MDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFE 119
F ++E +++ + + K + L E +L+ + E
Sbjct: 125 EAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELE 184
Query: 120 EAKN-TLCLI------QNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQT 172
+ K+ TL + K KE EK + + + + + D ++ ER + +
Sbjct: 185 KLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIED 244
Query: 173 AMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNR 232
+ + + +R G + +NE +SE + ++ + ED+ ++D + + K
Sbjct: 245 GISSTLPSKESRR-KGGLDYLKQVENETRNKSE-NEKNRNQEDNKVKDLNQEIEKLK--T 300
Query: 233 RVRKSEPLDE 242
+++ E L+E
Sbjct: 301 QIKHFESLEE 310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.128 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,578,306
Number of Sequences: 37866
Number of extensions: 501516
Number of successful extensions: 9787
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 517
Number of HSP's successfully gapped in prelim test: 854
Number of HSP's that attempted gapping in prelim test: 4082
Number of HSP's gapped (non-prelim): 3986
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.