Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 134254446
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134254446 patched isoform L [Homo sapiens]
(1447 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134254446 patched isoform L [Homo sapiens] 2949 0.0
gi|134254432 patched isoform L' [Homo sapiens] 2813 0.0
gi|134254466 patched isoform M [Homo sapiens] 2811 0.0
gi|134254450 patched isoform S [Homo sapiens] 2643 0.0
gi|134254435 patched isoform S [Homo sapiens] 2643 0.0
gi|134254468 patched isoform S [Homo sapiens] 2643 0.0
gi|134254452 patched isoform S [Homo sapiens] 2643 0.0
gi|52145305 patched 2 [Homo sapiens] 1279 0.0
gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens] 130 7e-30
gi|156231353 Niemann-Pick C1-like protein 1 isoform 2 [Homo sapi... 126 1e-28
gi|156231351 Niemann-Pick C1-like protein 1 isoform 1 [Homo sapi... 110 1e-23
gi|239754873 PREDICTED: similar to hCG2040393 [Homo sapiens] 92 4e-18
gi|239749412 PREDICTED: hypothetical protein XP_002347031 [Homo ... 92 4e-18
gi|239743547 PREDICTED: hypothetical protein XP_002342883 [Homo ... 92 4e-18
gi|194018513 patched domain containing 3 [Homo sapiens] 84 8e-16
gi|148271104 patched domain containing 1 [Homo sapiens] 82 3e-15
gi|148277106 hypothetical protein LOC442213 [Homo sapiens] 79 2e-14
gi|66932902 SREBF chaperone protein [Homo sapiens] 70 1e-11
gi|149274653 patched domain containing 2 [Homo sapiens] 53 2e-06
gi|25952134 dispatched A [Homo sapiens] 50 1e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 48 8e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 48 8e-05
gi|150417989 cyclin K isoform 1 [Homo sapiens] 45 5e-04
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 44 9e-04
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 44 0.001
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 43 0.003
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 42 0.003
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 42 0.003
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 42 0.003
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 42 0.003
>gi|134254446 patched isoform L [Homo sapiens]
Length = 1447
Score = 2949 bits (7644), Expect = 0.0
Identities = 1447/1447 (100%), Positives = 1447/1447 (100%)
Query: 1 MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAF 60
MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAF
Sbjct: 1 MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAF 60
Query: 61 ALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAAN 120
ALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAAN
Sbjct: 61 ALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAAN 120
Query: 121 LETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLD 180
LETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLD
Sbjct: 121 LETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLD 180
Query: 181 SALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAK 240
SALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAK
Sbjct: 181 SALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAK 240
Query: 241 LQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPA 300
LQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPA
Sbjct: 241 LQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPA 300
Query: 301 DPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHAL 360
DPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHAL
Sbjct: 301 DPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHAL 360
Query: 361 QTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVL 420
QTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVL
Sbjct: 361 QTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVL 420
Query: 421 SFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALS 480
SFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALS
Sbjct: 421 SFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALS 480
Query: 481 VAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGEC 540
VAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGEC
Sbjct: 481 VAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGEC 540
Query: 541 LKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDL 600
LKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDL
Sbjct: 541 LKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDL 600
Query: 601 YRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQS 660
YRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQS
Sbjct: 601 YRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQS 660
Query: 661 TVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSL 720
TVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSL
Sbjct: 661 TVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSL 720
Query: 721 HCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDI 780
HCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDI
Sbjct: 721 HCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDI 780
Query: 781 VPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQL 840
VPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQL
Sbjct: 781 VPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQL 840
Query: 841 PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDIS 900
PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDIS
Sbjct: 841 PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDIS 900
Query: 901 QLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR 960
QLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR
Sbjct: 901 QLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR 960
Query: 961 LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQ 1020
LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQ
Sbjct: 961 LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQ 1020
Query: 1021 YIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSA 1080
YIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSA
Sbjct: 1021 YIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSA 1080
Query: 1081 VPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLML 1140
VPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLML
Sbjct: 1081 VPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLML 1140
Query: 1141 AGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEP 1200
AGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEP
Sbjct: 1141 AGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEP 1200
Query: 1201 PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATE 1260
PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATE
Sbjct: 1201 PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATE 1260
Query: 1261 NPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRR 1320
NPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRR
Sbjct: 1261 NPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRR 1320
Query: 1321 DAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVA 1380
DAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVA
Sbjct: 1321 DAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVA 1380
Query: 1381 VHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEER 1440
VHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEER
Sbjct: 1381 VHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEER 1440
Query: 1441 PRGSSSN 1447
PRGSSSN
Sbjct: 1441 PRGSSSN 1447
>gi|134254432 patched isoform L' [Homo sapiens]
Length = 1446
Score = 2813 bits (7291), Expect = 0.0
Identities = 1381/1381 (100%), Positives = 1381/1381 (100%)
Query: 67 KGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVE 126
KGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVE
Sbjct: 66 KGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVE 125
Query: 127 ELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQAS 186
ELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQAS
Sbjct: 126 ELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQAS 185
Query: 187 RVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTA 246
RVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTA
Sbjct: 186 RVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTA 245
Query: 247 YLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPA 306
YLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPA
Sbjct: 246 YLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPA 305
Query: 307 TAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQL 366
TAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQL
Sbjct: 306 TAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQL 365
Query: 367 MTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTT 426
MTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTT
Sbjct: 366 MTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTT 425
Query: 427 LDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLG 486
LDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLG
Sbjct: 426 LDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLG 485
Query: 487 LCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGA 546
LCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGA
Sbjct: 486 LCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGA 545
Query: 547 SVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDR 606
SVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDR
Sbjct: 546 SVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDR 605
Query: 607 RLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRT 666
RLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRT
Sbjct: 606 RLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRT 665
Query: 667 EYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPP 726
EYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPP
Sbjct: 666 EYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPP 725
Query: 727 CTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETR 786
CTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETR
Sbjct: 726 CTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETR 785
Query: 787 EYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLH 846
EYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLH
Sbjct: 786 EYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLH 845
Query: 847 YFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQR 906
YFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQR
Sbjct: 846 YFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQR 905
Query: 907 LVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAA 966
LVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAA
Sbjct: 906 LVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAA 965
Query: 967 EPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRH 1026
EPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRH
Sbjct: 966 EPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRH 1025
Query: 1027 WLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVIL 1086
WLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVIL
Sbjct: 1026 WLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVIL 1085
Query: 1087 IASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFD 1146
IASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFD
Sbjct: 1086 IASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFD 1145
Query: 1147 FIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVR 1206
FIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVR
Sbjct: 1146 FIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVR 1205
Query: 1207 FAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAH 1266
FAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAH
Sbjct: 1206 FAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAH 1265
Query: 1267 STVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEIS 1326
STVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEIS
Sbjct: 1266 STVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEIS 1325
Query: 1327 TEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPV 1386
TEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPV
Sbjct: 1326 TEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPV 1385
Query: 1387 PGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSS 1446
PGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSS
Sbjct: 1386 PGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSS 1445
Query: 1447 N 1447
N
Sbjct: 1446 N 1446
>gi|134254466 patched isoform M [Homo sapiens]
Length = 1381
Score = 2811 bits (7286), Expect = 0.0
Identities = 1380/1380 (100%), Positives = 1380/1380 (100%)
Query: 68 GKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEE 127
GKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEE
Sbjct: 2 GKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEE 61
Query: 128 LWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASR 187
LWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASR
Sbjct: 62 LWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASR 121
Query: 188 VHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAY 247
VHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAY
Sbjct: 122 VHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAY 181
Query: 248 LLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPAT 307
LLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPAT
Sbjct: 182 LLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPAT 241
Query: 308 APNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLM 367
APNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLM
Sbjct: 242 APNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLM 301
Query: 368 TPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTL 427
TPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTL
Sbjct: 302 TPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTL 361
Query: 428 DDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGL 487
DDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGL
Sbjct: 362 DDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGL 421
Query: 488 CSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGAS 547
CSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGAS
Sbjct: 422 CSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGAS 481
Query: 548 VALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRR 607
VALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRR
Sbjct: 482 VALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRR 541
Query: 608 LDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTE 667
LDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTE
Sbjct: 542 LDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTE 601
Query: 668 YDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPC 727
YDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPC
Sbjct: 602 YDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPC 661
Query: 728 TKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETRE 787
TKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETRE
Sbjct: 662 TKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETRE 721
Query: 788 YDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHY 847
YDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHY
Sbjct: 722 YDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHY 781
Query: 848 FRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRL 907
FRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRL
Sbjct: 782 FRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRL 841
Query: 908 VDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAE 967
VDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAE
Sbjct: 842 VDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAE 901
Query: 968 PIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHW 1027
PIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHW
Sbjct: 902 PIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHW 961
Query: 1028 LLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILI 1087
LLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILI
Sbjct: 962 LLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILI 1021
Query: 1088 ASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDF 1147
ASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDF
Sbjct: 1022 ASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDF 1081
Query: 1148 IVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRF 1207
IVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRF
Sbjct: 1082 IVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRF 1141
Query: 1208 AMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHS 1267
AMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHS
Sbjct: 1142 AMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHS 1201
Query: 1268 TVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEIST 1327
TVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEIST
Sbjct: 1202 TVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEIST 1261
Query: 1328 EGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVP 1387
EGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVP
Sbjct: 1262 EGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVP 1321
Query: 1388 GPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
GPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN
Sbjct: 1322 GPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1381
>gi|134254450 patched isoform S [Homo sapiens]
Length = 1296
Score = 2644 bits (6852), Expect = 0.0
Identities = 1296/1296 (100%), Positives = 1296/1296 (100%)
Query: 152 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 211
MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT
Sbjct: 1 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 60
Query: 212 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 271
ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI
Sbjct: 61 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 120
Query: 272 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 331
NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS
Sbjct: 121 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 180
Query: 332 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 391
RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK
Sbjct: 181 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 240
Query: 392 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 451
AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA
Sbjct: 241 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 300
Query: 452 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 511
YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG
Sbjct: 301 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 360
Query: 512 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 571
VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR
Sbjct: 361 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 420
Query: 572 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 631
AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT
Sbjct: 421 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 480
Query: 632 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 691
DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT
Sbjct: 481 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 540
Query: 692 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 751
VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV
Sbjct: 541 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 600
Query: 752 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 811
VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD
Sbjct: 601 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 660
Query: 812 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 871
YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN
Sbjct: 661 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 720
Query: 872 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 931
NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP
Sbjct: 721 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 780
Query: 932 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 991
VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI
Sbjct: 781 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 840
Query: 992 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 1051
EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW
Sbjct: 841 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 900
Query: 1052 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 1111
TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK
Sbjct: 901 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 960
Query: 1112 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1171
NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL
Sbjct: 961 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1020
Query: 1172 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1231
PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV
Sbjct: 1021 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1080
Query: 1232 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1291
SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG
Sbjct: 1081 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1140
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1351
SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN
Sbjct: 1141 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1200
Query: 1352 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1411
PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED
Sbjct: 1201 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1260
Query: 1412 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN
Sbjct: 1261 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1296
>gi|134254435 patched isoform S [Homo sapiens]
Length = 1296
Score = 2644 bits (6852), Expect = 0.0
Identities = 1296/1296 (100%), Positives = 1296/1296 (100%)
Query: 152 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 211
MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT
Sbjct: 1 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 60
Query: 212 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 271
ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI
Sbjct: 61 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 120
Query: 272 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 331
NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS
Sbjct: 121 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 180
Query: 332 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 391
RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK
Sbjct: 181 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 240
Query: 392 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 451
AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA
Sbjct: 241 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 300
Query: 452 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 511
YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG
Sbjct: 301 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 360
Query: 512 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 571
VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR
Sbjct: 361 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 420
Query: 572 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 631
AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT
Sbjct: 421 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 480
Query: 632 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 691
DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT
Sbjct: 481 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 540
Query: 692 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 751
VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV
Sbjct: 541 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 600
Query: 752 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 811
VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD
Sbjct: 601 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 660
Query: 812 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 871
YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN
Sbjct: 661 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 720
Query: 872 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 931
NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP
Sbjct: 721 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 780
Query: 932 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 991
VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI
Sbjct: 781 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 840
Query: 992 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 1051
EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW
Sbjct: 841 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 900
Query: 1052 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 1111
TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK
Sbjct: 901 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 960
Query: 1112 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1171
NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL
Sbjct: 961 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1020
Query: 1172 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1231
PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV
Sbjct: 1021 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1080
Query: 1232 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1291
SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG
Sbjct: 1081 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1140
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1351
SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN
Sbjct: 1141 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1200
Query: 1352 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1411
PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED
Sbjct: 1201 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1260
Query: 1412 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN
Sbjct: 1261 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1296
>gi|134254468 patched isoform S [Homo sapiens]
Length = 1296
Score = 2644 bits (6852), Expect = 0.0
Identities = 1296/1296 (100%), Positives = 1296/1296 (100%)
Query: 152 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 211
MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT
Sbjct: 1 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 60
Query: 212 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 271
ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI
Sbjct: 61 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 120
Query: 272 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 331
NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS
Sbjct: 121 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 180
Query: 332 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 391
RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK
Sbjct: 181 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 240
Query: 392 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 451
AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA
Sbjct: 241 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 300
Query: 452 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 511
YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG
Sbjct: 301 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 360
Query: 512 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 571
VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR
Sbjct: 361 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 420
Query: 572 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 631
AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT
Sbjct: 421 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 480
Query: 632 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 691
DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT
Sbjct: 481 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 540
Query: 692 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 751
VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV
Sbjct: 541 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 600
Query: 752 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 811
VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD
Sbjct: 601 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 660
Query: 812 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 871
YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN
Sbjct: 661 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 720
Query: 872 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 931
NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP
Sbjct: 721 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 780
Query: 932 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 991
VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI
Sbjct: 781 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 840
Query: 992 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 1051
EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW
Sbjct: 841 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 900
Query: 1052 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 1111
TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK
Sbjct: 901 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 960
Query: 1112 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1171
NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL
Sbjct: 961 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1020
Query: 1172 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1231
PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV
Sbjct: 1021 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1080
Query: 1232 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1291
SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG
Sbjct: 1081 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1140
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1351
SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN
Sbjct: 1141 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1200
Query: 1352 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1411
PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED
Sbjct: 1201 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1260
Query: 1412 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN
Sbjct: 1261 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1296
>gi|134254452 patched isoform S [Homo sapiens]
Length = 1296
Score = 2644 bits (6852), Expect = 0.0
Identities = 1296/1296 (100%), Positives = 1296/1296 (100%)
Query: 152 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 211
MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT
Sbjct: 1 MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELIT 60
Query: 212 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 271
ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI
Sbjct: 61 ETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKI 120
Query: 272 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 331
NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS
Sbjct: 121 NYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLS 180
Query: 332 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 391
RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK
Sbjct: 181 RKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDK 240
Query: 392 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 451
AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA
Sbjct: 241 AAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLA 300
Query: 452 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 511
YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG
Sbjct: 301 YACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVG 360
Query: 512 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 571
VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR
Sbjct: 361 VDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALR 420
Query: 572 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 631
AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT
Sbjct: 421 AFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYT 480
Query: 632 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 691
DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT
Sbjct: 481 DTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVT 540
Query: 692 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 751
VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV
Sbjct: 541 VTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKV 600
Query: 752 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 811
VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD
Sbjct: 601 VVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKAD 660
Query: 812 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 871
YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN
Sbjct: 661 YPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPN 720
Query: 872 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 931
NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP
Sbjct: 721 NYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDP 780
Query: 932 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 991
VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI
Sbjct: 781 VAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAI 840
Query: 992 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 1051
EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW
Sbjct: 841 EKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPW 900
Query: 1052 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 1111
TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK
Sbjct: 901 TAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDK 960
Query: 1112 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1171
NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL
Sbjct: 961 NRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1020
Query: 1172 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1231
PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV
Sbjct: 1021 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1080
Query: 1232 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1291
SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG
Sbjct: 1081 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1140
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1351
SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN
Sbjct: 1141 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRN 1200
Query: 1352 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1411
PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED
Sbjct: 1201 PASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFED 1260
Query: 1412 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN
Sbjct: 1261 PHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1296
>gi|52145305 patched 2 [Homo sapiens]
Length = 1203
Score = 1279 bits (3310), Expect = 0.0
Identities = 642/1136 (56%), Positives = 836/1136 (73%), Gaps = 31/1136 (2%)
Query: 53 PSYCDAA-FALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGA 111
PSY A A QI G KAPLWLRA FQ LLF LGC IQ++CGK L +GLL FGA
Sbjct: 12 PSYTPPARTAAPQILAGSL---KAPLWLRAYFQGLLFSLGCGIQRHCGKVLFLGLLAFGA 68
Query: 112 FAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLT 171
A+GL+ A +ETN+E+LWVEVG RVS+EL+YT++K+GEEA + Q++IQT ++EG N+LT
Sbjct: 69 LALGLRMAIIETNLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTARQEGENILT 128
Query: 172 TEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITP 231
EAL HL +AL AS+V V +Y + W L +CYKSG + E G ++++IE L+PC+I+TP
Sbjct: 129 PEALGLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENGMIERMIEKLFPCVILTP 188
Query: 232 LDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGY 291
LDCFWEGAKLQ G+AYL G+P ++WTN DP + LEEL ++ + E+L+KA+VG Y
Sbjct: 189 LDCFWEGAKLQGGSAYLPGRPDIQWTNLDPEQLLEELGPFA-SLEGFRELLDKAQVGQAY 247
Query: 292 MDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNST 351
+ RPCL+P D CP +APN +S + ++A L+GGCHG S K+MHWQEEL++GG ++
Sbjct: 248 VGRPCLHPDDLHCPPSAPNHHSRQAPNVAHELSGGCHGFSHKFMHWQEELLLGGMARDPQ 307
Query: 352 GKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSV 411
G+L+ A ALQ+ F LM+P+Q+YEHF+G I W+E++A+ +L+AWQR +V++ +++
Sbjct: 308 GELLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASTVLQAWQRRFVQLAQEAL 367
Query: 412 AQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGL 471
+N++Q++ +F++TTLDDIL +FS+VS RV GYLLMLAYAC+TMLRWDC++SQG+VGL
Sbjct: 368 PENASQQIHAFSSTTLDDILHAFSEVSAARVVGGYLLMLAYACVTMLRWDCAQSQGSVGL 427
Query: 472 AGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRI 531
AGVLLVAL+VA+GLGLC+L+GI+FNAATTQVLPFLALG+GVDDVFLLAHAF+E
Sbjct: 428 AGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDVFLLAHAFTEALPG--T 485
Query: 532 PFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLI 591
P ++R GECL+RTG SV LTSI+N+ AF MAAL+PIPALRAFSLQAA+VV F V+L+
Sbjct: 486 PLQERMGECLQRTGTSVVLTSINNMAAFLMAALVPIPALRAFSLQAAIVVGCTFVAVMLV 545
Query: 592 FPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFA 651
FPAILS+DL RR +RLD+ CCF+SPC ++VIQ+ PQ D P +H
Sbjct: 546 FPAILSLDLRRRHCQRLDVLCCFSSPCSAQVIQILPQELGD-------GTVPVGIAH--- 595
Query: 652 HETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDL 711
+ +TVQ T + + T P++ + P D L + STRDL
Sbjct: 596 ------LTATVQAFTHCEASSQHVVTILPPQAHLVPPP----SDPLGSELFSPGGSTRDL 645
Query: 712 LSQFSDS--SLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTT 769
L Q ++ C PC +W L+ FA +AP LL+ AK +V+ LF LLG+SLYG T
Sbjct: 646 LGQEEETRQKAACKSLPCARWNLAHFARYQFAPLLLQSHAKAIVLVLFGALLGLSLYGAT 705
Query: 770 RVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKA-DYPNIQHLLYDLHRSFSN 828
V+DGL LTD+VPR T+E+ F++AQ +YFS Y + +VTQ DY + Q L+DLH+ FS+
Sbjct: 706 LVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSS 765
Query: 829 VKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLV 888
+K V+ Q P+ WLHY+R+WLQG+Q AFD DW +G+I ++Y+NGS+DG LAYKLL+
Sbjct: 766 LKAVLPPPATQAPRTWLHYYRNWLQGIQAAFDQDWASGRITRHSYRNGSEDGALAYKLLI 825
Query: 889 QTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEW 948
QTG +P+D SQLT ++LVD +G+I P FY+ LT WVS+DP+ AASQAN P PEW
Sbjct: 826 QTGDAQEPLDFSQLTTRKLVDREGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEW 885
Query: 949 VHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSS 1008
+HDK D E LRIP A+P+E+AQFPF L GL+ T+DFVEAIE R C+ G+ +
Sbjct: 886 LHDKYDTTGE-NLRIPPAQPLEFAQFPFLLRGLQKTADFVEAIEGARAACAEAGQAGVHA 944
Query: 1009 YPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELF 1068
YP+G PFLFWEQY+GLR LL + ++L CTFLVCA+ LLNPWTAG+IV+VLA+MTVELF
Sbjct: 945 YPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLNPWTAGLIVLVLAMMTVELF 1004
Query: 1069 GMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLD 1128
G+MG +GIKLSA+PVVIL+ASVGIGVEFTVHVAL FLT G +N RA ALEH FAPV D
Sbjct: 1005 GIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPVTD 1064
Query: 1129 GAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEV 1184
GA+STLLG+LMLAGS FDFIVRYFFA L +LT+LG+L+GLVLLPVLLS GP PEV
Sbjct: 1065 GAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPPPEV 1120
Score = 31.2 bits (69), Expect = 7.6
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 5/35 (14%)
Query: 1359 SSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNP 1393
SS+P +TT S+TVA+HPPP+PG +P
Sbjct: 1147 SSLPQSFARVTT-----SMTVAIHPPPLPGAYIHP 1176
>gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]
Length = 1278
Score = 130 bits (328), Expect = 7e-30
Identities = 126/476 (26%), Positives = 214/476 (44%), Gaps = 66/476 (13%)
Query: 732 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 791
L F + Y+P LLK + +VI +F+G+L S+ +V GLD + +P ++ D+
Sbjct: 817 LFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYF 876
Query: 792 AAQFKYF-SFYNMYIVTQKA-DYP--------------NIQHLLYDLHRSFSNVKYVMLE 835
+ +Y + +Y V ++ DY N L+ + + Y +
Sbjct: 877 KSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIG 936
Query: 836 ENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGS--DDGVLAYKLLVQTGSR 893
P W+ + DW++ D T + + N S D + + L G
Sbjct: 937 F---APSSWIDDYFDWVKPQSSCCRVDNIT-----DQFCNASVVDPACVRCRPLTPEG-- 986
Query: 894 DKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKA 953
KQR D F +L ++S++P P + H A
Sbjct: 987 ----------KQRPQGGD-------FMRFLPMFLSDNP----------NPKCGKGGH--A 1017
Query: 954 DYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYT-SLGLSS---- 1008
Y + + + F Y L+ ++DF++A++K R I SN T ++G++
Sbjct: 1018 AYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYR 1077
Query: 1009 -YPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFL-LNPWTAGIIVMVLALMTVE 1066
+P ++F+EQY+ + + + V L FLV V L W+A I+ +A++ V
Sbjct: 1078 VFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVN 1137
Query: 1067 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAI-GDKNRRAVLALEHMFAP 1125
+FG+M L GI L+AV +V L+ S GI VEF H+ AF ++ G + RA AL HM +
Sbjct: 1138 MFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSS 1197
Query: 1126 VLDGAVSTLL-GVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGP 1180
V G T G+++LA ++ ++F + + +LG +GL+ LPVLLS+ GP
Sbjct: 1198 VFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGP 1253
Score = 130 bits (326), Expect = 1e-29
Identities = 77/233 (33%), Positives = 123/233 (52%), Gaps = 9/233 (3%)
Query: 387 WNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASG 445
+N+ + +AW++ ++ V N T +SFT +++D L SD V V
Sbjct: 571 YNDTEKLQRAQAWEKEFINFVKNYKNPNLT---ISFTAERSIEDELNRESDSDVFTVVIS 627
Query: 446 YLLMLAYACLTM-----LRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATT 500
Y +M Y L + R S+ ++G+AG+L+V SVA LG+ S IG+
Sbjct: 628 YAIMFLYISLALGHIKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVI 687
Query: 501 QVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFF 560
+V+PFL L VGVD++F+L A+ + + + + G L S+ L+S S AFF
Sbjct: 688 EVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFF 747
Query: 561 MAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 613
+ AL +PA+ FSL A + V +F + + F ++L +D+ R+E RLDIFCC
Sbjct: 748 LGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCC 800
>gi|156231353 Niemann-Pick C1-like protein 1 isoform 2 [Homo sapiens]
Length = 1332
Score = 126 bits (317), Expect = 1e-28
Identities = 140/544 (25%), Positives = 236/544 (43%), Gaps = 96/544 (17%)
Query: 732 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 791
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D+
Sbjct: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYF 887
Query: 792 AAQFKYFSF-----------YN------MYIVTQKADYPNI---QHLLYDLHRSFSNVKY 831
+YF YN M + A N Q + Y F Y
Sbjct: 888 LFLNRYFEVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATE--FPEQSY 945
Query: 832 VMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTG 891
+ + + W+ F DWL P++ +L +
Sbjct: 946 LAIPASS-----WVDDFIDWLT----------------PSS----------CCRLYISGP 974
Query: 892 SRDK--PIDISQLT--KQRLVDADGIINPSA--FYIYLTAWVSNDPVAYAASQANIRPHR 945
++DK P ++ L K + G + PS F+ YL W ND + + +
Sbjct: 975 NKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLP-WFLNDRPNIKCPKGGLAAY- 1032
Query: 946 PEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS-- 1003
T + + + + ++F Y L+++ D+ EA+ R + +N T+
Sbjct: 1033 ------------STSVNLTSDGQVLASRFMAYHKPLKNSQDYTEALRAARELAANITADL 1080
Query: 1004 -------LGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII 1056
+P +F+EQY+ + L +S+ L TF V + L +G++
Sbjct: 1081 RKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLL 1140
Query: 1057 -VMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKN--- 1112
++ + ++ V+ G M L GI +AV ++ L+++VG+ VEF H+ +F AI K
Sbjct: 1141 NLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSF--AISTKPTWL 1198
Query: 1113 RRAVLALEHMFAPVLDG-AVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLL 1171
RA A M + V G A++ L G+L+L ++ I +FF + ++T+LG+L+GLV L
Sbjct: 1199 ERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFL 1258
Query: 1172 PVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQT 1229
PV+LS+ G P+V+PA L + E + V A P H S +D+ +S +
Sbjct: 1259 PVILSYVG--PDVNPALALEQ---KRAEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEG 1313
Query: 1230 TVSG 1233
++ G
Sbjct: 1314 SIKG 1317
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 390 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 448
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
Query: 449 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 503
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
Query: 504 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 563
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
Query: 564 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 613
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
>gi|156231351 Niemann-Pick C1-like protein 1 isoform 1 [Homo
sapiens]
Length = 1359
Score = 110 bits (274), Expect = 1e-23
Identities = 66/230 (28%), Positives = 115/230 (50%), Gaps = 6/230 (2%)
Query: 390 DKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTT-TLDDILKSFSDVSVIRVASGYLL 448
D A + W+ ++E + + + ++F +L+D + + + A+ Y++
Sbjct: 583 DPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIV 642
Query: 449 MLAYACLTMLRWDCSK-----SQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVL 503
+ Y L + + S+ +GL GV +V +V A +G S +GI + QV+
Sbjct: 643 IFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVV 702
Query: 504 PFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA 563
PFL L VG D++F+ + + P E G L R S+ L S+S FF+ A
Sbjct: 703 PFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGA 762
Query: 564 LIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCC 613
L P+PA+R F+L + + V+ +F + + F A+LS+D R+E RLD+ CC
Sbjct: 763 LTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCC 812
Score = 103 bits (256), Expect = 2e-21
Identities = 82/278 (29%), Positives = 144/278 (51%), Gaps = 23/278 (8%)
Query: 972 AQFPFYLNGLRDTSDFVEAIEKVRTICSNYTS---------LGLSSYPNGYPFLFWEQYI 1022
++F Y L+++ D+ EA+ R + +N T+ +P +F+EQY+
Sbjct: 1074 SRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYL 1133
Query: 1023 GLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII-VMVLALMTVELFGMMGLIGIKLSAV 1081
+ L +S+ L TF V + L +G++ ++ + ++ V+ G M L GI +AV
Sbjct: 1134 TILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAV 1193
Query: 1082 PVVILIASVGIGVEFTVHVALAFLTAIGDKN---RRAVLALEHMFAPVLDG-AVSTLLGV 1137
++ L+++VG+ VEF H+ +F AI K RA A M + V G A++ L G+
Sbjct: 1194 SLINLVSAVGMSVEFVSHITRSF--AISTKPTWLERAKEATISMGSAVFAGVAMTNLPGI 1251
Query: 1138 LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPS 1197
L+L ++ I +FF + ++T+LG+L+GLV LPV+LS+ G P+V+PA L +
Sbjct: 1252 LVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVG--PDVNPALALEQ---KR 1306
Query: 1198 PEPPPSVVRFAMPPGHTH--SGSDSSDSEYSSQTTVSG 1233
E + V A P H S +D+ +S + ++ G
Sbjct: 1307 AEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKG 1344
Score = 48.9 bits (115), Expect = 4e-05
Identities = 27/67 (40%), Positives = 37/67 (55%)
Query: 732 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 791
L F +K YAPFLL + VV+ LFL L GVSLY + GLD +P+++ D+
Sbjct: 828 LLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYF 887
Query: 792 AAQFKYF 798
+YF
Sbjct: 888 LFLNRYF 894
>gi|239754873 PREDICTED: similar to hCG2040393 [Homo sapiens]
Length = 333
Score = 92.0 bits (227), Expect = 4e-18
Identities = 93/295 (31%), Positives = 113/295 (38%), Gaps = 52/295 (17%)
Query: 1186 PANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQ 1245
P + R P P P S R PG GS + + + RH +
Sbjct: 58 PGHTAPRTQQPKPSGPSSHPREPPLPGAVTGGS----LHFQEPPPLGAATAGSRHRQKPP 113
Query: 1246 GAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPS---NPRQQPHL-DSGSLPPGRQGQQ 1301
G E P +T R PPS HL SGS R
Sbjct: 114 SPGSR------HRWEPPPPGAATATGSRHRREPPSPGATTAGSCHLRSSGSTGTRRAPSH 167
Query: 1302 PR-------RDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWG---PRGARSHNP-- 1349
P R+ PRE PP P+ A EG S WG P+G R
Sbjct: 168 PAALQVPYTREGPREPT--PPAGPQGFAGSFCAEG-SRRGAEVGWGKLEPQGTRRTGSLG 224
Query: 1350 --RNPASTAMGSSVPG------------YCQPITTVTASASVTVAVHPPPVPGPGRNPRG 1395
+P S +G + G +C I + P PGP ++P+
Sbjct: 225 VDSSPLSETLGPAQCGSGRRRACSVLHHHCDGIRFRDCHCA------PSACPGPTQDPQA 278
Query: 1396 GLCPG---YPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
GLC G YP TDHGLF PH+ F V+ ER + KVEV ELQDVECEE PRGSSSN
Sbjct: 279 GLCTGQEGYPGTDHGLFMGPHLLFQVQGERTNLKVEVTELQDVECEEWPRGSSSN 333
>gi|239749412 PREDICTED: hypothetical protein XP_002347031 [Homo
sapiens]
Length = 333
Score = 92.0 bits (227), Expect = 4e-18
Identities = 93/295 (31%), Positives = 113/295 (38%), Gaps = 52/295 (17%)
Query: 1186 PANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQ 1245
P + R P P P S R PG GS + + + RH +
Sbjct: 58 PGHTAPRTQQPKPSGPSSHPREPPLPGAVTGGS----LHFQEPPPLGAATAGSRHRQKPP 113
Query: 1246 GAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPS---NPRQQPHL-DSGSLPPGRQGQQ 1301
G E P +T R PPS HL SGS R
Sbjct: 114 SPGSR------HRWEPPPPGAATATGSRHRREPPSPGATTAGSCHLRSSGSTGTRRAPSH 167
Query: 1302 PR-------RDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWG---PRGARSHNP-- 1349
P R+ PRE PP P+ A EG S WG P+G R
Sbjct: 168 PAALQVPYTREGPREPT--PPAGPQGFAGSFCAEG-SRRGAEVGWGKLEPQGTRRTGSLG 224
Query: 1350 --RNPASTAMGSSVPG------------YCQPITTVTASASVTVAVHPPPVPGPGRNPRG 1395
+P S +G + G +C I + P PGP ++P+
Sbjct: 225 VDSSPLSETLGPAQCGSGRRRACSVLHHHCDGIRFRDCHCA------PSACPGPTQDPQA 278
Query: 1396 GLCPG---YPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
GLC G YP TDHGLF PH+ F V+ ER + KVEV ELQDVECEE PRGSSSN
Sbjct: 279 GLCTGQEGYPGTDHGLFMGPHLLFQVQGERTNLKVEVTELQDVECEEWPRGSSSN 333
>gi|239743547 PREDICTED: hypothetical protein XP_002342883 [Homo
sapiens]
Length = 333
Score = 92.0 bits (227), Expect = 4e-18
Identities = 93/295 (31%), Positives = 113/295 (38%), Gaps = 52/295 (17%)
Query: 1186 PANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQ 1245
P + R P P P S R PG GS + + + RH +
Sbjct: 58 PGHTAPRTQQPKPSGPSSHPREPPLPGAVTGGS----LHFQEPPPLGAATAGSRHRQKPP 113
Query: 1246 GAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPS---NPRQQPHL-DSGSLPPGRQGQQ 1301
G E P +T R PPS HL SGS R
Sbjct: 114 SPGSR------HRWEPPPPGAATATGSRHRREPPSPGATTAGSCHLRSSGSTGTRRAPSH 167
Query: 1302 PR-------RDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWG---PRGARSHNP-- 1349
P R+ PRE PP P+ A EG S WG P+G R
Sbjct: 168 PAALQVPYTREGPREPT--PPAGPQGFAGSFCAEG-SRRGAEVGWGKLEPQGTRRTGSLG 224
Query: 1350 --RNPASTAMGSSVPG------------YCQPITTVTASASVTVAVHPPPVPGPGRNPRG 1395
+P S +G + G +C I + P PGP ++P+
Sbjct: 225 VDSSPLSETLGPAQCGSGRRRACSVLHHHCDGIRFRDCHCA------PSACPGPTQDPQA 278
Query: 1396 GLCPG---YPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN 1447
GLC G YP TDHGLF PH+ F V+ ER + KVEV ELQDVECEE PRGSSSN
Sbjct: 279 GLCTGQEGYPGTDHGLFMGPHLLFQVQGERTNLKVEVTELQDVECEEWPRGSSSN 333
>gi|194018513 patched domain containing 3 [Homo sapiens]
Length = 767
Score = 84.3 bits (207), Expect = 8e-16
Identities = 62/246 (25%), Positives = 120/246 (48%), Gaps = 20/246 (8%)
Query: 354 LVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQ 413
L+ A A++ ++ L T Y+ + ++++H+ D+ I +EVVH +
Sbjct: 316 LLRAKAMRLLYYLKTEDPEYD-VQSKQWLTHLL---DQFTNIKNILALKKIEVVHFT--- 368
Query: 414 NSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAG 473
S + L F T S + + V +A Y+L++ +A + R+DC +++ V G
Sbjct: 369 -SLSRQLEFEAT-------SVTVIPVFHLA--YILIILFAVTSCFRFDCIRNKMCVAAFG 418
Query: 474 VLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPF 533
V+ L+V +G GL IG+ F PFL LGVGVDD+F++ A+ +T N
Sbjct: 419 VISAFLAVVSGFGLLLHIGVPFVIIVAN-SPFLILGVGVDDMFIMISAWHKT--NLADDI 475
Query: 534 EDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFP 593
+R + S+ +T+I+N+ A + + +++ F + + ++F + + F
Sbjct: 476 RERMSNVYSKAAVSITITTITNILALYTGIMSSFRSVQCFCIYTGMTLLFCYFYNITCFG 535
Query: 594 AILSMD 599
A +++D
Sbjct: 536 AFMALD 541
Score = 60.5 bits (145), Expect = 1e-08
Identities = 37/128 (28%), Positives = 68/128 (53%), Gaps = 9/128 (7%)
Query: 732 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 791
+S F ++ PFL + ++K V+F+++ + S+YG V++GLDL ++ ++ +
Sbjct: 584 ISLFFRDYFGPFLTRSESKYFVVFIYVLYIISSIYGCFHVQEGLDLRNLASDDSYITPYF 643
Query: 792 AAQFKYFSFYN---MYIVTQKADY--PNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLH 846
+ YFS Y M IVT+K DY +++ L + + F YV +K L + WL
Sbjct: 644 NVEENYFSDYGPRVMVIVTKKVDYWDKDVRQKLENCTKIFEKNVYV----DKNLTEFWLD 699
Query: 847 YFRDWLQG 854
+ +L+G
Sbjct: 700 AYVQYLKG 707
>gi|148271104 patched domain containing 1 [Homo sapiens]
Length = 888
Score = 82.4 bits (202), Expect = 3e-15
Identities = 65/272 (23%), Positives = 126/272 (46%), Gaps = 24/272 (8%)
Query: 343 VGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRT 402
+GG +S ++ SA A+Q + Y+ IN D A E W+ +
Sbjct: 192 LGGVTVHSKDRVKSAEAIQLTY----------------YLQSINSLNDMVA---ERWESS 232
Query: 403 YVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDC 462
+ + V NS K+ +T+++L + + S VS + + +L++ A L DC
Sbjct: 233 FCDTVRLFQKSNSKVKMYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDC 292
Query: 463 SKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAF 522
+S+ +GL G++ ++L+ G+ +L G +N +T +PF+ LG G+ F + ++
Sbjct: 293 VRSKPWLGLLGLVTISLATLTAAGIINLTGGKYN-STFLGVPFVMLGHGLYGTFEMLSSW 351
Query: 523 SETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA--LIPIPALRAFSLQAAVV 580
+T +++ + ++RT + S +LT+ + F + A I A R F + +
Sbjct: 352 RKTREDQHV--KERTAAVYADSMLSFSLTTAMYLVTFGIGASPFTNIEAARIFCCNSCIA 409
Query: 581 VVFNFAMVLLIFPAILSMDLYRREDRRLDIFC 612
+ FN+ VL + + L Y + + IFC
Sbjct: 410 IFFNYLYVLSFYGSSLVFTGYIENNYQHSIFC 441
Score = 44.7 bits (104), Expect = 7e-04
Identities = 23/74 (31%), Positives = 40/74 (54%)
Query: 732 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 791
L F +++Y ++ K V+ +L + +L G +V +G DL++IV T+ ++
Sbjct: 483 LVCFLKRYYCDWITNTYVKPFVVLFYLIYISFALMGYLQVSEGSDLSNIVATATQTIEYT 542
Query: 792 AAQFKYFSFYNMYI 805
AQ KYFS Y+ I
Sbjct: 543 TAQQKYFSNYSPVI 556
Score = 31.6 bits (70), Expect = 5.8
Identities = 36/155 (23%), Positives = 66/155 (42%), Gaps = 16/155 (10%)
Query: 1029 LLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVE--LFGMMGLIGIKLSAVPVVIL 1086
LLF S L A L+N W + L +++VE + G M L ++L + V+ L
Sbjct: 710 LLFFSAFLV------ADSLINVW------ITLTVVSVEFGVIGFMTLWKVELDCISVLCL 757
Query: 1087 IASVGIGVEFTVHVALAFLTAIGDKNRRAVL-ALEHMFAPVLDGAVSTLLGVLMLAGSEF 1145
I + ++ + F+ + V ALE +L + ++G++ LA
Sbjct: 758 IYGINYTIDNCAPMLSTFVLGKDFTRTKWVKNALEVHGVAILQSYLCYIVGLIPLAAVPS 817
Query: 1146 DFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGP 1180
+ F L ++ + + +LPV+L+F P
Sbjct: 818 NLTCT-LFRCLFLIAFVTFFHCFAILPVILTFLPP 851
>gi|148277106 hypothetical protein LOC442213 [Homo sapiens]
Length = 829
Score = 79.3 bits (194), Expect = 2e-14
Identities = 62/260 (23%), Positives = 112/260 (43%), Gaps = 7/260 (2%)
Query: 397 EAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLT 456
E W+ + +++ + ++ ++ S + +L S ++ +V +L+L A L+
Sbjct: 175 EKWENEFCKLIRKLQEEHQELQLYSLASFSLWRDFHKTSILARSKVLVSLVLILTTATLS 234
Query: 457 MLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVF 516
DC +S+ +GL GVL V +S+ G+ + +N +T +PF A+G G VF
Sbjct: 235 SSMKDCLRSKPFLGLLGVLTVCISIITAAGIFFITDGKYN-STLLGIPFFAMGHGTKGVF 293
Query: 517 LLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAA--LIPIPALRAFS 574
L + T +N +PF+DR + + +TS F M A I A++ F
Sbjct: 294 ELLSGWRRTKEN--LPFKDRIADAYSDVMVTYTMTSSLYFITFGMGASPFTNIEAVKVFC 351
Query: 575 LQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCF--TSPCVSRVIQVEPQAYTD 632
V ++ N+ + F + L ++R IFCC ++ + R +D
Sbjct: 352 QNMCVSILLNYFYIFSFFGSCLVFAGQLEQNRYHSIFCCKIPSAEYLDRKPVWFQTVMSD 411
Query: 633 THDNTRYSPPPPYSSHSFAH 652
H T + PY H H
Sbjct: 412 GHQQTSHHETNPYQHHFIQH 431
Score = 43.5 bits (101), Expect = 0.001
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 9/183 (4%)
Query: 732 LSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFI 791
+ F +HY ++ K V+ L+L S G ++ DG ++ +++ ++ +
Sbjct: 429 IQHFLREHYNEWITNIYVKPFVVILYLIYASFSFMGCLQISDGANIINLLASDSPSVSYA 488
Query: 792 AAQFKYFSFYNMYI---VTQKADYPN--IQHLLYDLHRSFSNVKYV-MLEENKQLPKMWL 845
Q KYFS Y+ I V + +Y N +Q L L F+ V +V + ++ +
Sbjct: 489 MVQQKYFSNYSPVIGFYVYEPLEYWNSSVQDDLRRLCSGFTAVSWVEQYYQFLKVSNVSA 548
Query: 846 HYFRDWLQGLQDAFDSDWETGKIMPNNY--KNGSDDGVLAYKL-LVQTGSRDKPIDISQL 902
+ D++ LQ +F E + K G + ++A +L LV SRDK +I+++
Sbjct: 549 NNKSDFISVLQSSFLKKPEFQHFRNDIIFSKAGDESNIIASRLYLVARTSRDKQKEITEV 608
Query: 903 TKQ 905
++
Sbjct: 609 LEK 611
Score = 41.6 bits (96), Expect = 0.006
Identities = 39/174 (22%), Positives = 78/174 (44%), Gaps = 12/174 (6%)
Query: 1016 LFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTA----GIIVMVLALMTVEL--FG 1069
+F ++ + H+ L VL F V V +L + G ++L++ ++EL G
Sbjct: 625 VFNPSFVFMDHYSLSVTVPVLIAGFGVLLVLILTFFLVIHPLGNFWLILSVTSIELGVLG 684
Query: 1070 MMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLA-LEHMFAPVLD 1128
+M L + + + ++ LI ++ ++ + F+ A + + + L+ +L
Sbjct: 685 LMTLWNVDMDCISILCLIYTLNFAIDHCAPLLFTFVLATEHTRTQCIKSSLQDHGTAILQ 744
Query: 1129 GAVSTLLGV--LMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGP 1180
S L+G+ L+ S F + F L + +L+ V+LPV L+FF P
Sbjct: 745 NVTSFLIGLVPLLFVPSNLTFTL---FKCLLLTGGCTLLHCFVILPVFLTFFPP 795
>gi|66932902 SREBF chaperone protein [Homo sapiens]
Length = 1279
Score = 70.1 bits (170), Expect = 1e-11
Identities = 45/182 (24%), Positives = 90/182 (49%), Gaps = 6/182 (3%)
Query: 439 VIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAA 498
+I + + Y+++ AY + + D KS+ + LA V+ V S+ +GLC+L G++
Sbjct: 285 LIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLN 344
Query: 499 TTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTA 558
++ P+L + +G+++V +L + T + + R + L S+ + +
Sbjct: 345 GGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKL--RIAQGLSSESWSIMKNMATELGI 402
Query: 559 FFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRRE----DRRLDIFCCF 614
+ +PA++ F L A V +V +F + +L F +LS+D+ R E ++RL C
Sbjct: 403 ILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNKRLPPEACL 462
Query: 615 TS 616
S
Sbjct: 463 PS 464
>gi|149274653 patched domain containing 2 [Homo sapiens]
Length = 1392
Score = 53.1 bits (126), Expect = 2e-06
Identities = 87/394 (22%), Positives = 152/394 (38%), Gaps = 65/394 (16%)
Query: 387 WNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGY 446
W E +A +++ TYV ++ A+ ST KV T D V R +
Sbjct: 415 WEEQRAK--FQSFVVTYVAML----AKQSTSKVQVLYGGT------DLFDYEVRRTFNND 462
Query: 447 LLM--LAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLI-GISFNAATTQVL 503
+L+ ++ +C+ L + + + G+ + LS L L ++ GI + V
Sbjct: 463 MLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVA 522
Query: 504 PFLALGVGVDDVFLLAHAFSETGQNKRIPFED---RTGECLKRTGASVALTSISNVTAFF 560
F+ +G+GVDDVF+ + + + ED R ++ G + TS++ A+
Sbjct: 523 AFVIVGIGVDDVFVFINTYRQATH-----LEDPQLRMIHTVQTAGKATFFTSLTTAAAYA 577
Query: 561 MAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVS 620
IPA+ F L +++V + VL+ PA L + + + +P
Sbjct: 578 ANVFSQIPAVHDFGLFMSLIVSCCWLAVLVTMPAALGL------------WSLYLAP--- 622
Query: 621 RVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAE 680
+E T H N + FA Q+ D + E
Sbjct: 623 ----LESSCQTSCHQNCSRKTSLHFPGDVFAAPEQVGGSPAQGPIPYLDDDIPLLEVEEE 678
Query: 681 PRS-EIS-VQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEK 738
P S E+ V V+V+ + L Q +T S L+ Q + H W L S
Sbjct: 679 PVSLELGDVSLVSVSPEGL--QPASNTGSRGHLIVQLQELLHH--------WVLWSAV-- 726
Query: 739 HYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVR 772
K++ V++ LF+ +L +SL +R+R
Sbjct: 727 ---------KSRWVIVGLFVSILILSLVFASRLR 751
Score = 32.3 bits (72), Expect = 3.4
Identities = 35/167 (20%), Positives = 67/167 (40%), Gaps = 39/167 (23%)
Query: 1028 LLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILI 1087
+LL + V+L+ +VC V + W+ G ++ AV + L
Sbjct: 1205 ILLLLPVLLSILGIVCLVVTIMYWS----------------------GWEMGAVEAISLS 1242
Query: 1088 ASVGIGVEFTVHVALAFL------------TAIGDKNRRAVLALEHMFAPVLDGAVSTLL 1135
VG V++ VH+ +L A + R + A+ H+ ++ A++T++
Sbjct: 1243 ILVGSSVDYCVHLVEGYLLAGENLPPHQAEDARTQRQWRTLEAVRHVGVAIVSSALTTVI 1302
Query: 1136 GVLMLAGSEFDFIVRY--FFAVLAILTILGVLNGLVLLPVLLSFFGP 1180
+ L F I + F ++A+ T + +L L + LL P
Sbjct: 1303 ATVPLF---FCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAP 1346
>gi|25952134 dispatched A [Homo sapiens]
Length = 1524
Score = 50.4 bits (119), Expect = 1e-05
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 506 LALGVGVDDVFLLAHAFSETGQNK-RIPFEDRTGECLKRTGASVALTSISNVTAFFMAAL 564
+ +G+G DD F+L ++ T +K + L+ S+ +TS + AF+ +
Sbjct: 565 ILVGIGADDAFVLCDVWNYTKFDKPHAETSETVSITLQHAALSMFVTSFTTAAAFYANYV 624
Query: 565 IPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSP 617
I A+R F + A ++ N+ +++ PA++ + E L+IF CF P
Sbjct: 625 SNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVL----HERYLLNIFTCFKKP 673
Score = 41.2 bits (95), Expect = 0.007
Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 21/173 (12%)
Query: 987 FVEAIEKVRTI---CSNYTSLGLSSYPNGYP-------FLFWEQYIGLRHWLLLFISVVL 1036
F A EK+ ++ S LSS P G F++ L L+ + + +
Sbjct: 933 FTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSV 992
Query: 1037 ACTFLVCAVFLLNPWTAGIIVMVLALMTVE-----LFGMMGLIGIKLSAVPVVILIASVG 1091
A F +V LL W II+ + A++++ G + L+G +L+ + V + +VG
Sbjct: 993 AVAF---SVMLLTTWN--IIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVG 1047
Query: 1092 IGVEFTVHVALAF-LTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGS 1143
+ V+F VH +A+ L D+ + + +L + + + A++T + M+ S
Sbjct: 1048 LSVDFAVHYGVAYRLAPDPDREGKVIFSLSRVGSAMAMAALTTFVAGAMMMPS 1100
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 47.8 bits (112), Expect = 8e-05
Identities = 67/245 (27%), Positives = 89/245 (36%), Gaps = 32/245 (13%)
Query: 1178 FGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEE 1237
F P P +SP L TP P+ PP++ A+PP S + S T S +
Sbjct: 380 FLPSPPLSP------LATPPPQAPPAL---ALPPLQA-PPSPPASPPLSPLATPSPQAPN 429
Query: 1238 LRHYEAQQGAGGPAHQVIVEATENPVFAH--STVVHPESR----------HHPPSNPRQQ 1285
Q P V+A +P + S P S+ PPS P
Sbjct: 430 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 489
Query: 1286 PHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGAR 1345
P S + PP Q P PP + PPP P A S P++ P
Sbjct: 490 PMSPSATPPP--QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 547
Query: 1346 SHNPRNPASTAMGSSVPGYCQPITTVTAS--ASVTV-AVHPPPVPGPGRNPRG-----GL 1397
+ P +P +T + P P+ V S AS T+ A PP PGP + G L
Sbjct: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 607
Query: 1398 CPGYP 1402
PG P
Sbjct: 608 APGPP 612
Score = 31.6 bits (70), Expect = 5.8
Identities = 41/164 (25%), Positives = 56/164 (34%), Gaps = 34/164 (20%)
Query: 1196 PSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVI 1255
P P PPPS P T SG D + S+ +T EELR Y++ G
Sbjct: 609 PGPPPPPS-----RSPSSTLSGPDLAGHSSSATST----PEELRGYDSGPEGGA------ 653
Query: 1256 VEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLP------PGR--------QGQQ 1301
A P A HP + P+ P LP PG + +
Sbjct: 654 --AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
Query: 1302 PRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGAR 1345
P P G P P + + +G S+R+ P+ AR
Sbjct: 712 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS---PKQAR 752
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 47.8 bits (112), Expect = 8e-05
Identities = 67/245 (27%), Positives = 89/245 (36%), Gaps = 32/245 (13%)
Query: 1178 FGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEE 1237
F P P +SP L TP P+ PP++ A+PP S + S T S +
Sbjct: 341 FLPSPPLSP------LATPPPQAPPAL---ALPPLQA-PPSPPASPPLSPLATPSPQAPN 390
Query: 1238 LRHYEAQQGAGGPAHQVIVEATENPVFAH--STVVHPESR----------HHPPSNPRQQ 1285
Q P V+A +P + S P S+ PPS P
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450
Query: 1286 PHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGAR 1345
P S + PP Q P PP + PPP P A S P++ P
Sbjct: 451 PMSPSATPPP--QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508
Query: 1346 SHNPRNPASTAMGSSVPGYCQPITTVTAS--ASVTV-AVHPPPVPGPGRNPRG-----GL 1397
+ P +P +T + P P+ V S AS T+ A PP PGP + G L
Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568
Query: 1398 CPGYP 1402
PG P
Sbjct: 569 APGPP 573
Score = 35.8 bits (81), Expect = 0.31
Identities = 53/218 (24%), Positives = 72/218 (33%), Gaps = 36/218 (16%)
Query: 1180 PYPEVSPANG---LNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSE 1236
P + +PA G + L TPSP PPS + PP + S + SQ T S
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSP---SAPP--SLQTLPSPPATPPSQATTS---- 329
Query: 1237 ELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPG 1296
G P Q HS + P P+ P L +LPP
Sbjct: 330 ----------LGSPTLQA----------THSFLPSPPLSPLATPPPQAPPAL---ALPPL 366
Query: 1297 RQGQQPRRDPPREGL-WPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPAST 1355
+ P PP L P P P A + S P + P + P +P++T
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426
Query: 1356 AMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNP 1393
+ P P V S + + P P P P
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464
Score = 31.6 bits (70), Expect = 5.8
Identities = 41/164 (25%), Positives = 56/164 (34%), Gaps = 34/164 (20%)
Query: 1196 PSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVI 1255
P P PPPS P T SG D + S+ +T EELR Y++ G
Sbjct: 570 PGPPPPPS-----RSPSSTLSGPDLAGHSSSATST----PEELRGYDSGPEGGA------ 614
Query: 1256 VEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLP------PGR--------QGQQ 1301
A P A HP + P+ P LP PG + +
Sbjct: 615 --AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 672
Query: 1302 PRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGAR 1345
P P G P P + + +G S+R+ P+ AR
Sbjct: 673 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS---PKQAR 713
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 45.1 bits (105), Expect = 5e-04
Identities = 55/204 (26%), Positives = 69/204 (33%), Gaps = 37/204 (18%)
Query: 1194 PTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQ 1253
P P +PPP R PP ++ S+ S Y S E + ++ GP++
Sbjct: 407 PAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMS-------GEGYQSLQSMMKTEGPSYG 459
Query: 1254 VIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWP 1313
+ A P AH P H P NP P PP P PP G P
Sbjct: 460 ALPPAYGPP--AHL----PYHPHVYPPNPPPPP-----VPPPPASFPPPAIPPPTPGYPP 508
Query: 1314 PPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTA 1373
PP T + P R P A +P G +P P V
Sbjct: 509 PP----------PTYNPNFPPPPPRLPPTHAVPPHP------PPGLGLPPASYPPPAVPP 552
Query: 1374 SASVTVAVHPPPVPGPGRNPRGGL 1397
V PPP+P PG P GGL
Sbjct: 553 GGQPPV---PPPIPPPGMPPVGGL 573
Score = 32.3 bits (72), Expect = 3.4
Identities = 43/168 (25%), Positives = 53/168 (31%), Gaps = 28/168 (16%)
Query: 1256 VEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGR---------QGQQP---- 1302
V+AT+ P HP H PP P + P S G +G Q
Sbjct: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
Query: 1303 -RRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSV 1361
+ + P G PP Y P + H P N P P + A+
Sbjct: 451 MKTEGPSYGALPPAYGP---PAHLPYHPHVYPPN----PPPPPVPPPPASFPPPAIPPPT 503
Query: 1362 PGYCQPITTVTAS-------ASVTVAVHPPPVPGPGRNPRGGLCPGYP 1402
PGY P T + T AV P P PG G P P P
Sbjct: 504 PGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVP 551
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 44.3 bits (103), Expect = 9e-04
Identities = 39/133 (29%), Positives = 50/133 (37%), Gaps = 31/133 (23%)
Query: 1281 NPRQQPHLDSGSLPPGRQGQQPRRDPPREG--LWPPPYRPRRDAFEISTEGHSGPSNRAR 1338
+PR P G PP + G QP+ PP G PPP R +G P
Sbjct: 89 SPRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNR------PQGPPPPGKPQG 140
Query: 1339 WGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGP--------G 1390
P+G +S +PR+P G G QP PPP PG G
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQP-------------QGPPPPPGKPQGPPPQGG 187
Query: 1391 RNPRGGLCPGYPE 1403
+ P+G PG P+
Sbjct: 188 KKPQGPPPPGKPQ 200
Score = 36.6 bits (83), Expect = 0.18
Identities = 35/126 (27%), Positives = 48/126 (38%), Gaps = 24/126 (19%)
Query: 1289 DSGSLPPGR-QGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGP--RGAR 1345
+S SL G QG P+ +G PPP +P+ + + P GP +G +
Sbjct: 27 ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 86
Query: 1346 SHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGP--------GRNPRGGL 1397
S +PR+P G G QP PPP PG G P+G
Sbjct: 87 SRSPRSPPGKPQGPPPQGGNQP-------------QGPPPPPGKPQGPPPQGGNRPQGPP 133
Query: 1398 CPGYPE 1403
PG P+
Sbjct: 134 PPGKPQ 139
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 43.5 bits (101), Expect = 0.001
Identities = 47/218 (21%), Positives = 81/218 (37%), Gaps = 44/218 (20%)
Query: 1180 PYPEV----SPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLS 1235
P+P+V SP R P P+ P++ A+ PG + S S + QTT++ L
Sbjct: 662 PHPKVPAPFSPPPSKPRSPNPAA---PALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQ 718
Query: 1236 EELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPP 1295
E ++ ++P + P +HPP P ++P + +
Sbjct: 719 ES----------------PVISKDQSPPPS------PPPSYHPPPPPTKKPEVVVEAPSA 756
Query: 1296 GRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPAST 1355
++P +DP WPPP P + ++S P S P P+ +
Sbjct: 757 SETAEEPLQDPN----WPPPPPPAPEEQDLSMADFPPPEEAF----FSVASPEPAGPSGS 808
Query: 1356 AMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNP 1393
S P ++S++ + + PP P P P
Sbjct: 809 PELVSSP-------AASSSSATALQIQPPGSPDPPPAP 839
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 42.7 bits (99), Expect = 0.003
Identities = 39/142 (27%), Positives = 50/142 (35%), Gaps = 31/142 (21%)
Query: 1272 PESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREG--LWPPPYRPRRDAFEISTEG 1329
P + P P P G PP + G QP+ PP G PPP + +G
Sbjct: 40 PPQGGNKPQGPPSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNK------PQG 91
Query: 1330 HSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGP 1389
P P+G +S +PR+P G G QP PPP PG
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-------------QGPPPPPGK 138
Query: 1390 --------GRNPRGGLCPGYPE 1403
G P+G PG P+
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQ 160
Score = 32.7 bits (73), Expect = 2.6
Identities = 37/141 (26%), Positives = 48/141 (34%), Gaps = 39/141 (27%)
Query: 1274 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREG--LWPPPYRPRRDAFEISTEGHS 1331
S PP P+ PP + G QP+ PP G PPP + +G
Sbjct: 172 SSRSPPGKPQG---------PPPQGGNQPQGPPPPPGKPQGPPPQGGNK------PQGPP 216
Query: 1332 GPSNRARWGPRG-ARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGP- 1389
P P+G +S + R+P G G QP PPP PG
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP-------------QGPPPPPGKP 263
Query: 1390 -------GRNPRGGLCPGYPE 1403
G P+G PG P+
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQ 284
Score = 32.7 bits (73), Expect = 2.6
Identities = 41/169 (24%), Positives = 57/169 (33%), Gaps = 50/169 (29%)
Query: 1272 PESRHHPPSNPRQQP----HLDSGSLPPGR-QGQQPR--------RDPPREGLWPPPY-- 1316
P+ PP P+ P + G PPG+ QG P+ R PP + PPP
Sbjct: 191 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGG 250
Query: 1317 -----------RPRRDAFEISTEGHSGPSNRARWGP---RGARSHNPRNPASTAMGSSVP 1362
+P+ + + P GP G++S + R+P G
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310
Query: 1363 GYCQPITTVTASASVTVAVHPPPVPGP--------GRNPRGGLCPGYPE 1403
G QP PPP PG G P+G PG P+
Sbjct: 311 GGNQP-------------QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo
sapiens]
Length = 1125
Score = 42.4 bits (98), Expect = 0.003
Identities = 47/181 (25%), Positives = 64/181 (35%), Gaps = 41/181 (22%)
Query: 1182 PEVSPANGLNRLPTPSPEP----------PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1231
P P L R P P P PP FAMPP H G + +
Sbjct: 840 PPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGM 899
Query: 1232 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1291
GL G GGP + + R PP P+QQP +
Sbjct: 900 PGLGGP------GPGPGGPEDR-------------------DGRQQPPQQPQQQPQPQAP 934
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPR--GARSHNP 1349
P +Q QQP PP + P +P++ + + +SG ++ R+G R G R N
Sbjct: 935 QQPQQQQQQQP---PPSQQPPPTQQQPQQFRNDNRQQFNSG-RDQERFGRRSFGNRVEND 990
Query: 1350 R 1350
R
Sbjct: 991 R 991
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo
sapiens]
Length = 1132
Score = 42.4 bits (98), Expect = 0.003
Identities = 47/181 (25%), Positives = 64/181 (35%), Gaps = 41/181 (22%)
Query: 1182 PEVSPANGLNRLPTPSPEP----------PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1231
P P L R P P P PP FAMPP H G + +
Sbjct: 847 PPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGM 906
Query: 1232 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1291
GL G GGP + + R PP P+QQP +
Sbjct: 907 PGLGGP------GPGPGGPEDR-------------------DGRQQPPQQPQQQPQPQAP 941
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPR--GARSHNP 1349
P +Q QQP PP + P +P++ + + +SG ++ R+G R G R N
Sbjct: 942 QQPQQQQQQQP---PPSQQPPPTQQQPQQFRNDNRQQFNSG-RDQERFGRRSFGNRVEND 997
Query: 1350 R 1350
R
Sbjct: 998 R 998
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
sapiens]
Length = 1147
Score = 42.4 bits (98), Expect = 0.003
Identities = 47/181 (25%), Positives = 64/181 (35%), Gaps = 41/181 (22%)
Query: 1182 PEVSPANGLNRLPTPSPEP----------PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTV 1231
P P L R P P P PP FAMPP H G + +
Sbjct: 862 PPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGM 921
Query: 1232 SGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSG 1291
GL G GGP + + R PP P+QQP +
Sbjct: 922 PGLGGP------GPGPGGPEDR-------------------DGRQQPPQQPQQQPQPQAP 956
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPR--GARSHNP 1349
P +Q QQP PP + P +P++ + + +SG ++ R+G R G R N
Sbjct: 957 QQPQQQQQQQP---PPSQQPPPTQQQPQQFRNDNRQQFNSG-RDQERFGRRSFGNRVEND 1012
Query: 1350 R 1350
R
Sbjct: 1013 R 1013
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 42.4 bits (98), Expect = 0.003
Identities = 43/151 (28%), Positives = 58/151 (38%), Gaps = 28/151 (18%)
Query: 1278 PPSNPRQQPHLDSGSLPPGRQG---QQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPS 1334
PP P QQ PP +Q Q P P + PPP P +D+ + GP+
Sbjct: 61 PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP--PPQDSSKPVVAQGPGPA 118
Query: 1335 NRARWGPRGARSHNPRNPAST----------------AMGSSVPGYCQPITTVTASASVT 1378
P + S P P ++ A+ S+ PG P T ++ T
Sbjct: 119 PGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPG-APPPTPPSSGVPTT 177
Query: 1379 V--AVHPPP----VPGPGRNPRGGLCPGYPE 1403
A PPP VPGPG P+ G PG P+
Sbjct: 178 PPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK 208
Score = 33.1 bits (74), Expect = 2.0
Identities = 45/178 (25%), Positives = 55/178 (30%), Gaps = 23/178 (12%)
Query: 1180 PYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELR 1239
P P P P P P V + P S +S S + SG
Sbjct: 87 PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG------ 140
Query: 1240 HYEAQQGAG-GPAHQVIVEATENPVFA-------HSTVVHPESRHHPPSNPRQQPHLDSG 1291
A G+G GP T P A P PP P P G
Sbjct: 141 ---APPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVP----G 193
Query: 1292 SLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNP 1349
P +QG P P+ G P +P + GH P +R PRG R H+P
Sbjct: 194 PGPGPKQGPGP--GGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249
Score = 32.0 bits (71), Expect = 4.4
Identities = 55/226 (24%), Positives = 72/226 (31%), Gaps = 44/226 (19%)
Query: 1179 GPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEEL 1238
GP P + P + P P+ PP PP H + S+ +
Sbjct: 55 GPKPPIPPPPPHQQQQQPPPQQPPP----QQPPPHQPPPHPQPHQQQQPPPPPQDSSKPV 110
Query: 1239 RHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSN---PRQQPHLDSGSLPP 1295
QG GPA V + P + + P + PP + P P S PP
Sbjct: 111 ----VAQGP-GPAPGV---GSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPP 162
Query: 1296 GRQGQQPRRD-----PPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPR 1350
G P PP+ G PPP + G GP + GP G +
Sbjct: 163 GAPPPTPPSSGVPTTPPQAGGPPPP--------PAAVPG-PGPGPKQGPGPGGPK----- 208
Query: 1351 NPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGG 1396
G +PG +P S T HP P G PRGG
Sbjct: 209 -------GGKMPGGPKPGGGPGLS---TPGGHPKPPHRGGGEPRGG 244
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,690,764
Number of Sequences: 37866
Number of extensions: 3149697
Number of successful extensions: 16355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 335
Number of HSP's that attempted gapping in prelim test: 14948
Number of HSP's gapped (non-prelim): 1603
length of query: 1447
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1332
effective length of database: 13,892,928
effective search space: 18505380096
effective search space used: 18505380096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.