NPC1L1 5922

Name: NPC1L1	Sequence: fasta or formatted (1359aa)		NCBI GI: 156231351
Description: Niemann-Pick C1-like protein 1 isoform 1		Referenced in: Stomach, Small Intestine, and Colon Common Drug Targets Hedgehog and Related Pathways Additional Membrane Functions
Other entries for this name: alt prot [1332aa] Niemann-Pick C1-like protein 1 isoform 2
Composition: Amino acid Percentage Count Longest homopolymer A alanine 9.3 126 3 C cysteine 3.1 42 3 D aspartate 3.8 52 2 E glutamate 3.9 53 2 F phenylalanine 5.5 75 3 G glycine 6.4 87 2 H histidine 1.5 21 1 I isoleucine 4.6 63 3 K lysine 2.7 37 2 L leucine 14.1 191 4 M methionine 2.2 30 1 N asparagine 4.3 58 2 P proline 5.3 72 3 Q glutamine 4.0 54 1 R arginine 4.0 55 2 S serine 8.5 116 2 T threonine 5.3 72 2 V valine 6.8 92 2 W tryptophan 1.3 17 1 Y tyrosine 3.4 46 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 Niemann-Pick C1-like protein 1 isoform 1 NPC1L1 0.974 Niemann-Pick C1-like protein 1 isoform 2 NPC1 0.323 Niemann-Pick disease, type C1 precursor PTCH2 0.032 patched 2 PTCH1 0.032 patched isoform S PTCH1 0.032 patched isoform S PTCH1 0.032 patched isoform S PTCH1 0.032 patched isoform S PTCH1 0.032 patched isoform L' PTCH1 0.032 patched isoform M PTCH1 0.032 patched isoform L PTCHD3 0.027 patched domain containing 3 C6orf138 0.026 hypothetical protein LOC442213 SCAP 0.018 SREBF chaperone protein PTCHD1 0.017 patched domain containing 1 PTCHD2 0.009 patched domain containing 2 DISP2 0.008 dispatched B DISP1 0.006 dispatched A CCNJL 0.006 cyclin J-like C20orf30 0.006 hypothetical protein LOC29058 isoform 1 SORBS1 0.005 sorbin and SH3 domain containing 1 isoform 4 CENPL 0.004 centromere protein L isoform 1 LOC100289388 0.004 PREDICTED: hypothetical protein XP_002343124 CNGA1 0.004 cyclic nucleotide gated channel alpha 1 isoform 1 [... IFT20 0.004 intraflagellar transport protein IFT20 MYL10 0.004 myosin, light chain 10, regulatory LOC100293423 0.004 PREDICTED: hypothetical protein LOC100290837 0.004 PREDICTED: hypothetical protein XP_002347267 C15orf40 0.004 hypothetical protein LOC123207 isoform b NOS3 0.004 nitric oxide synthase 3 isoform 4 Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.