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Search of human proteins with 55956914
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956914 myosin binding protein H [Homo sapiens]
(477 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956914 myosin binding protein H [Homo sapiens] 959 0.0
gi|194018539 myosin binding protein H-like [Homo sapiens] 473 e-133
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ... 458 e-129
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ... 458 e-129
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ... 457 e-129
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 457 e-128
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ... 448 e-126
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 434 e-122
gi|148839296 immunoglobulin-like and fibronectin type III domain... 192 4e-49
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] 186 3e-47
gi|110349719 titin isoform N2-A [Homo sapiens] 155 8e-38
gi|110349717 titin isoform novex-2 [Homo sapiens] 155 8e-38
gi|110349713 titin isoform novex-1 [Homo sapiens] 155 8e-38
gi|110349715 titin isoform N2-B [Homo sapiens] 155 8e-38
gi|140560917 myomesin 1 isoform b [Homo sapiens] 88 2e-17
gi|155969693 myomesin family, member 3 [Homo sapiens] 82 1e-15
gi|156104903 myomesin 2 [Homo sapiens] 78 2e-14
gi|140560919 myomesin 1 isoform a [Homo sapiens] 73 6e-13
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 70 4e-12
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 70 4e-12
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 70 4e-12
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 67 5e-11
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 67 5e-11
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 65 2e-10
gi|93102361 palladin [Homo sapiens] 62 1e-09
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 62 1e-09
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 62 1e-09
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 62 1e-09
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 62 1e-09
gi|157785645 SPEG complex locus [Homo sapiens] 61 3e-09
>gi|55956914 myosin binding protein H [Homo sapiens]
Length = 477
Score = 959 bits (2479), Expect = 0.0
Identities = 477/477 (100%), Positives = 477/477 (100%)
Query: 1 MMEKNTSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTA 60
MMEKNTSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTA
Sbjct: 1 MMEKNTSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTA 60
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV
Sbjct: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL
Sbjct: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSD 240
RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSD
Sbjct: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSD 240
Query: 241 SGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
SGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG
Sbjct: 241 SGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
Query: 301 YMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAH 360
YMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAH
Sbjct: 301 YMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAH 360
Query: 361 IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKM 420
IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKM
Sbjct: 361 IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKM 420
Query: 421 EIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
EIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH
Sbjct: 421 EIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
>gi|194018539 myosin binding protein H-like [Homo sapiens]
Length = 354
Score = 473 bits (1216), Expect = e-133
Identities = 235/349 (67%), Positives = 276/349 (79%), Gaps = 9/349 (2%)
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPP-------AMLDQPIHIRENIEAPKIRVPRHLRQT 183
T +A G K L+V S A A PP A P + E PKI +PR LRQT
Sbjct: 5 TAPEVAAGSK--LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQT 62
Query: 184 YIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR 243
YIR+VG+TVNL IPFQGKPKPQA WTH+G ALD++RVS+R G+QDSILFIR AQR+DSGR
Sbjct: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
Query: 244 YELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
Y+L V++ LEA A IDILVIE+PGPP SI+L+DVWG +A L+WTPPQDTGNT LLGY V
Sbjct: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Query: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQK 363
QKAD K+G WFTVLE YH T+C +SDLIIGNSY+FRVF+EN CGLS +A +T +LAHIQK
Sbjct: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
Query: 364 ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
A K KGF +RDFSEAP FTQPLAD T+ GY+TQLFC VRASP+PKIIW+KNKM+IQ
Sbjct: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
Query: 424 GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
GNPKYRAL+ G+C+LEIRKP PFD G+YTCKA+N LGEASVDCR++VK
Sbjct: 303 GNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
Score = 43.5 bits (101), Expect = 4e-04
Identities = 40/156 (25%), Positives = 57/156 (36%), Gaps = 19/156 (12%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P + L DV S T+ W PP+ G L GY ++ + W V T
Sbjct: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI-HI--------------RENIEAPKIR 175
V +L +G+ + RV A + G A + + HI R+ EAPK
Sbjct: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHN 211
P T G L + P+P+ W N
Sbjct: 265 QPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKN 297
>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
sapiens]
Length = 1123
Score = 458 bits (1178), Expect = e-129
Identities = 221/427 (51%), Positives = 293/427 (68%), Gaps = 5/427 (1%)
Query: 54 APTASTATKPAPPSED-----VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A +KP+ PS V S P LLT+D V+ ++VT+ W PP+ +G GL GYVLE
Sbjct: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
C EG +W+ + + T+ T+ L K +RV AV++AGA P QPI ++E
Sbjct: 756 YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 815
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQD 228
IE PKIR+PRHL+QTYIR+VGE VNL IPFQGKP+P+ TW +G +D ++++R + D
Sbjct: 816 IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 875
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+I+FIR A+RS SG+Y+L V+V+ A IDI +I++PGPP +++ DVWG N AL WT
Sbjct: 876 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 935
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
PP+D GN + GY +QKADKK+ +WFTV+E YH T+ TI++L+IGN Y FRVFSEN+CGL
Sbjct: 936 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 995
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
S AT+TKE A I + K + + DFSEAP FTQPL + + GY+ L CSVR +
Sbjct: 996 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1055
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
PKPKI WMKNK+ I +P+YR S QGVCTLEIRKPSP+D G Y CKA+N LG ++C+
Sbjct: 1056 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1115
Query: 469 LEVKASA 475
LEVK A
Sbjct: 1116 LEVKVIA 1122
Score = 89.7 bits (221), Expect = 5e-18
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G + L+IP G+P P+A W+ A+ S R+ + S L I A+R DSG Y +
Sbjct: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
++ E EA A I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
Query: 307 DKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
K++ +W + + TT +I G +Y R+F+ N G+S
Sbjct: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 703
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/94 (25%), Positives = 46/94 (48%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P+ T+ +V ++WEPP G + GY +E ++ +S W+ ++ T
Sbjct: 618 DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 677
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
+ + G + +R+ AV++ G P+M +P
Sbjct: 678 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
Score = 38.9 bits (89), Expect = 0.010
Identities = 73/314 (23%), Positives = 118/314 (37%), Gaps = 45/314 (14%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTG 225
+ P I V + L T GE V L+ + W NG + R +R
Sbjct: 337 VREPPIMVTKQLEDT-TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 394
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDI--LVIEKPGPPSSIRLLDVWGCNA 283
+ IL I A ++D+ Y + AK +D+ L I P ++ L G
Sbjct: 395 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL----GKEI 450
Query: 284 ALQWTPPQDT-GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR--- 339
L+ ++ G G VQ++D+ L+ H I L+I N+ +
Sbjct: 451 CLKCEISENIPGKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANALTEDEGD 500
Query: 340 -VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS 398
VF+ + ++ A K + PK I D +A + +A G
Sbjct: 501 YVFAPDAYNVTLPA----------KVHVIDPPK--IILDGLDADNTVTVIA------GNK 542
Query: 399 TQLFCSVRASPKPKIIWMK-NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
+L + P PK +W + +K ++G+ + R S TL I DSGVY
Sbjct: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
Query: 458 NVLGEASVDCRLEV 471
N GEA +++V
Sbjct: 603 NEAGEAHASIKVKV 616
>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
sapiens]
Length = 1148
Score = 458 bits (1178), Expect = e-129
Identities = 221/427 (51%), Positives = 293/427 (68%), Gaps = 5/427 (1%)
Query: 54 APTASTATKPAPPSED-----VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A +KP+ PS V S P LLT+D V+ ++VT+ W PP+ +G GL GYVLE
Sbjct: 721 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
C EG +W+ + + T+ T+ L K +RV AV++AGA P QPI ++E
Sbjct: 781 YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQD 228
IE PKIR+PRHL+QTYIR+VGE VNL IPFQGKP+P+ TW +G +D ++++R + D
Sbjct: 841 IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+I+FIR A+RS SG+Y+L V+V+ A IDI +I++PGPP +++ DVWG N AL WT
Sbjct: 901 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
PP+D GN + GY +QKADKK+ +WFTV+E YH T+ TI++L+IGN Y FRVFSEN+CGL
Sbjct: 961 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
S AT+TKE A I + K + + DFSEAP FTQPL + + GY+ L CSVR +
Sbjct: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
PKPKI WMKNK+ I +P+YR S QGVCTLEIRKPSP+D G Y CKA+N LG ++C+
Sbjct: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
Query: 469 LEVKASA 475
LEVK A
Sbjct: 1141 LEVKVIA 1147
Score = 89.7 bits (221), Expect = 5e-18
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G + L+IP G+P P+A W+ A+ S R+ + S L I A+R DSG Y +
Sbjct: 565 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
++ E EA A I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 625 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
Query: 307 DKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
K++ +W + + TT +I G +Y R+F+ N G+S
Sbjct: 685 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 728
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/94 (25%), Positives = 46/94 (48%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P+ T+ +V ++WEPP G + GY +E ++ +S W+ ++ T
Sbjct: 643 DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 702
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
+ + G + +R+ AV++ G P+M +P
Sbjct: 703 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
Score = 38.9 bits (89), Expect = 0.010
Identities = 73/314 (23%), Positives = 118/314 (37%), Gaps = 45/314 (14%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTG 225
+ P I V + L T GE V L+ + W NG + R +R
Sbjct: 362 VREPPIMVTKQLEDT-TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 419
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDI--LVIEKPGPPSSIRLLDVWGCNA 283
+ IL I A ++D+ Y + AK +D+ L I P ++ L G
Sbjct: 420 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL----GKEI 475
Query: 284 ALQWTPPQDT-GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR--- 339
L+ ++ G G VQ++D+ L+ H I L+I N+ +
Sbjct: 476 CLKCEISENIPGKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANALTEDEGD 525
Query: 340 -VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS 398
VF+ + ++ A K + PK I D +A + +A G
Sbjct: 526 YVFAPDAYNVTLPA----------KVHVIDPPK--IILDGLDADNTVTVIA------GNK 567
Query: 399 TQLFCSVRASPKPKIIWMK-NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
+L + P PK +W + +K ++G+ + R S TL I DSGVY
Sbjct: 568 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
Query: 458 NVLGEASVDCRLEV 471
N GEA +++V
Sbjct: 628 NEAGEAHASIKVKV 641
>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
sapiens]
Length = 1171
Score = 457 bits (1176), Expect = e-129
Identities = 220/424 (51%), Positives = 292/424 (68%), Gaps = 5/424 (1%)
Query: 54 APTASTATKPAPPSED-----VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A +KP+ PS V S P LLT+D V+ ++VT+ W PP+ +G GL GYVLE
Sbjct: 721 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
C EG +W+ + + T+ T+ L K +RV AV++AGA P QPI ++E
Sbjct: 781 YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQD 228
IE PKIR+PRHL+QTYIR+VGE VNL IPFQGKP+P+ TW +G +D ++++R + D
Sbjct: 841 IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+I+FIR A+RS SG+Y+L V+V+ A IDI +I++PGPP +++ DVWG N AL WT
Sbjct: 901 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
PP+D GN + GY +QKADKK+ +WFTV+E YH T+ TI++L+IGN Y FRVFSEN+CGL
Sbjct: 961 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
S AT+TKE A I + K + + DFSEAP FTQPL + + GY+ L CSVR +
Sbjct: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
PKPKI WMKNK+ I +P+YR S QGVCTLEIRKPSP+D G Y CKA+N LG ++C+
Sbjct: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
Query: 469 LEVK 472
LEVK
Sbjct: 1141 LEVK 1144
Score = 89.7 bits (221), Expect = 5e-18
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G + L+IP G+P P+A W+ A+ S R+ + S L I A+R DSG Y +
Sbjct: 565 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
++ E EA A I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 625 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
Query: 307 DKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
K++ +W + + TT +I G +Y R+F+ N G+S
Sbjct: 685 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 728
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/94 (25%), Positives = 46/94 (48%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P+ T+ +V ++WEPP G + GY +E ++ +S W+ ++ T
Sbjct: 643 DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 702
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
+ + G + +R+ AV++ G P+M +P
Sbjct: 703 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
Score = 38.9 bits (89), Expect = 0.010
Identities = 73/314 (23%), Positives = 118/314 (37%), Gaps = 45/314 (14%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTG 225
+ P I V + L T GE V L+ + W NG + R +R
Sbjct: 362 VREPPIMVTKQLEDT-TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 419
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDI--LVIEKPGPPSSIRLLDVWGCNA 283
+ IL I A ++D+ Y + AK +D+ L I P ++ L G
Sbjct: 420 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL----GKEI 475
Query: 284 ALQWTPPQDT-GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR--- 339
L+ ++ G G VQ++D+ L+ H I L+I N+ +
Sbjct: 476 CLKCEISENIPGKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANALTEDEGD 525
Query: 340 -VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS 398
VF+ + ++ A K + PK I D +A + +A G
Sbjct: 526 YVFAPDAYNVTLPA----------KVHVIDPPK--IILDGLDADNTVTVIA------GNK 567
Query: 399 TQLFCSVRASPKPKIIWMK-NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
+L + P PK +W + +K ++G+ + R S TL I DSGVY
Sbjct: 568 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
Query: 458 NVLGEASVDCRLEV 471
N GEA +++V
Sbjct: 628 NEAGEAHASIKVKV 641
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 457 bits (1175), Expect = e-128
Identities = 219/415 (52%), Positives = 286/415 (68%), Gaps = 1/415 (0%)
Query: 58 STATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEW 117
S TKP P S PL L ++DV+ ++ T+ W PP R+G G+ GY++E C EG+ EW
Sbjct: 725 SMNTKPFMPIAPT-SEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW 783
Query: 118 VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVP 177
VP + P+ TV+NL G + L RV V+ AG PA L QP+ IRE E PKIR+P
Sbjct: 784 VPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLP 843
Query: 178 RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQ 237
RHLRQTYIR+VGE +NL +PFQGKP+PQ WT G LD+ RV +RT D D++ F+R A
Sbjct: 844 RHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAA 903
Query: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
RSDSG YEL+V++E+++ A I I V+EK GPP ++ + +VWG NA ++W P+D GN+E
Sbjct: 904 RSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSE 963
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
++GY VQKADKKT +WF V ER T+CT+SDLI+GN Y FRV++EN+CGLS S V+K
Sbjct: 964 IMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKN 1023
Query: 358 LAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK 417
A I K I KP + E DF AP F PL D GYS L C+VR PKPK++WMK
Sbjct: 1024 TARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMK 1083
Query: 418 NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
NKMEI+ +PK+ + QGV TL IR+PSPFD+G YTC+A+N LGEA +C+LEV+
Sbjct: 1084 NKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVR 1138
Score = 84.0 bits (206), Expect = 3e-16
Identities = 58/193 (30%), Positives = 86/193 (44%), Gaps = 6/193 (3%)
Query: 170 EAPKIRVP---RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ--RVSMRT 224
E PKI + + + G + L + G+P P ATW + R +
Sbjct: 537 EPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEK 596
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
S I SAQR D GRY + V E A I + V++ P PP ++R+ V A
Sbjct: 597 RVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAI 656
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSE 343
L W PP G + GY+V++ K + +W + E + TT + +I G Y RVF+
Sbjct: 657 LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAV 716
Query: 344 NLCGLSTSATVTK 356
N G+S + TK
Sbjct: 717 NAIGVSQPSMNTK 729
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/94 (26%), Positives = 44/94 (46%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + V + WEPP G + GY++E ++G+ W+ ++ T
Sbjct: 637 DVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTET 696
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
+ G + +RV AV++ G P+M +P
Sbjct: 697 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
sapiens]
Length = 1141
Score = 448 bits (1153), Expect = e-126
Identities = 222/445 (49%), Positives = 294/445 (66%), Gaps = 23/445 (5%)
Query: 54 APTASTATKPAPPSED-----VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A +KP+ PS V S P LLT+D V+ ++VT+ W PP+ +G GL GYVLE
Sbjct: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
Query: 109 LCREG------------------ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSS 150
C EG A +W+ + + T+ T+ L K +RV AV++
Sbjct: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
Query: 151 AGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH 210
AGA P QPI ++E IE PKIR+PRHL+QTYIR+VGE VNL IPFQGKP+P+ TW
Sbjct: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
Query: 211 NGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP 270
+G +D ++++R + D+I+FIR A+RS SG+Y+L V+V+ A IDI +I++PGPP
Sbjct: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 935
Query: 271 SSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDL 330
+++ DVWG N AL WTPP+D GN + GY +QKADKK+ +WFTV+E YH T+ TI++L
Sbjct: 936 QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
Query: 331 IIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLAD 390
+IGN Y FRVFSEN+CGLS AT+TKE A I + K + + DFSEAP FTQPL +
Sbjct: 996 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1055
Query: 391 HTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSG 450
+ GY+ L CSVR +PKPKI WMKNK+ I +P+YR S QGVCTLEIRKPSP+D G
Sbjct: 1056 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
Query: 451 VYTCKAINVLGEASVDCRLEVKASA 475
Y CKA+N LG ++C+LEVK A
Sbjct: 1116 TYCCKAVNDLGTVEIECKLEVKVIA 1140
Score = 89.7 bits (221), Expect = 5e-18
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G + L+IP G+P P+A W+ A+ S R+ + S L I A+R DSG Y +
Sbjct: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
++ E EA A I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
Query: 307 DKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
K++ +W + + TT +I G +Y R+F+ N G+S
Sbjct: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 703
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/94 (25%), Positives = 46/94 (48%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P+ T+ +V ++WEPP G + GY +E ++ +S W+ ++ T
Sbjct: 618 DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 677
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
+ + G + +R+ AV++ G P+M +P
Sbjct: 678 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
Score = 38.9 bits (89), Expect = 0.010
Identities = 73/314 (23%), Positives = 118/314 (37%), Gaps = 45/314 (14%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTG 225
+ P I V + L T GE V L+ + W NG + R +R
Sbjct: 337 VREPPIMVTKQLEDT-TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 394
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDI--LVIEKPGPPSSIRLLDVWGCNA 283
+ IL I A ++D+ Y + AK +D+ L I P ++ L G
Sbjct: 395 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL----GKEI 450
Query: 284 ALQWTPPQDT-GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR--- 339
L+ ++ G G VQ++D+ L+ H I L+I N+ +
Sbjct: 451 CLKCEISENIPGKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANALTEDEGD 500
Query: 340 -VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS 398
VF+ + ++ A K + PK I D +A + +A G
Sbjct: 501 YVFAPDAYNVTLPA----------KVHVIDPPK--IILDGLDADNTVTVIA------GNK 542
Query: 399 TQLFCSVRASPKPKIIWMK-NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
+L + P PK +W + +K ++G+ + R S TL I DSGVY
Sbjct: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
Query: 458 NVLGEASVDCRLEV 471
N GEA +++V
Sbjct: 603 NEAGEAHASIKVKV 616
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 434 bits (1117), Expect = e-122
Identities = 211/424 (49%), Positives = 281/424 (66%), Gaps = 5/424 (1%)
Query: 54 APTASTATKPAPPSEDV-----PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A ++P+P S+ PS P L ++DVS ++V++ W PPER+G GL GY +E
Sbjct: 848 AVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVE 907
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
C EG SEWV T V++L G + L RV A + AG G P +P+ ++E
Sbjct: 908 YCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEI 967
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQD 228
++ P++++PRHLRQT ++VGE VNL IPFQGKP+PQ TWT G L + VS+R D
Sbjct: 968 LQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTD 1027
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+ILFIR+A+R SG Y++TVR+E++E KA + + V++KP PP +R+ D WG N AL+W
Sbjct: 1028 TILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWK 1087
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
PPQD GNTEL GY VQKADKKT +WFTVLE Y T C + +LIIGN Y FRVFS+N+ G
Sbjct: 1088 PPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGF 1147
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
S A TKE I + I +P + DFSEAPSFTQPL + + GY+ L C+VR S
Sbjct: 1148 SDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGS 1207
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
PKPKI W KN +++ + ++R S+QGV TLEIRKP PFD G+Y C+A N+ GEA +CR
Sbjct: 1208 PKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECR 1267
Query: 469 LEVK 472
LEV+
Sbjct: 1268 LEVR 1271
Score = 69.7 bits (169), Expect = 5e-12
Identities = 51/213 (23%), Positives = 88/213 (41%), Gaps = 33/213 (15%)
Query: 170 EAPKIRV--PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWT------HNGHALDSQRVS 221
E PKI + P + T + G + L +P G P P W + A +
Sbjct: 643 EPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAP 702
Query: 222 MRTGDQD------------------------SILFIRSAQRSDSGRYELTVRVEDLEAKA 257
TGD D SI + A++ D G Y +TV+ E +
Sbjct: 703 EDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQV 762
Query: 258 VIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV- 316
+ + VI+ P P++ ++ +V + +QW PP G +LGY++++ KK+ +W +
Sbjct: 763 NLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLN 822
Query: 317 LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
+ + +I G Y RV++ N G+S
Sbjct: 823 FDLIQELSHEARRMIEGVVYEMRVYAVNAIGMS 855
Score = 56.2 bits (134), Expect = 6e-08
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 15/164 (9%)
Query: 13 SPEETASESA----KVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSE 68
+PE+T K E G V V E+T++ + + + T T P E
Sbjct: 701 APEDTGDSDEWVFDKKLLCETEGRVRV-ETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGE 759
Query: 69 D----------VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
D VP AP + +V S TV WEPP G + GY+LE ++ + W+
Sbjct: 760 DQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWM 819
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
++ + R + G + +RV AV++ G P+ QP
Sbjct: 820 RLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 192 bits (489), Expect = 4e-49
Identities = 129/425 (30%), Positives = 192/425 (45%), Gaps = 16/425 (3%)
Query: 49 APAPQAPTASTATKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRL 100
A AP P +P PPS+ V P L + D S++S+T+SW P+
Sbjct: 437 AVAPSGPG-----EPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGD 491
Query: 101 GLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLD 160
QGYV+ELC + +W+P + VT T + L G+ + +RV+AV+ G P+ LD
Sbjct: 492 EAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALD 551
Query: 161 QPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRV 220
+ PK V + +VG+TV + + F+ P P+ TW +G L + V
Sbjct: 552 TLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSV 611
Query: 221 SMRTGDQDSILFIRSAQRSDSGRYELTVR-VEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
++ T D + L I A SDSG Y + +R ++ E I V P P I L +
Sbjct: 612 TV-TKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRVAACPQAPGPIHLQENV 670
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR 339
+W P D L Y V G W +R H T+ ++ G+ Y FR
Sbjct: 671 PGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRIHTNRFTLLGILPGHEYHFR 730
Query: 340 VFSENLCGLSTSATVTKELAHIQKAD-IAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS 398
V ++N G S + ++ ++ D K + E D S+ P F L H G
Sbjct: 731 VVAKNELGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQGCE 790
Query: 399 TQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN 458
+ C+V+ SP+P + W KN ++GNP + GVC+L I SP DSG Y A N
Sbjct: 791 CCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAEN 850
Query: 459 VLGEA 463
LG+A
Sbjct: 851 TLGQA 855
Score = 79.7 bits (195), Expect = 5e-15
Identities = 52/170 (30%), Positives = 82/170 (48%), Gaps = 5/170 (2%)
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTGDQDSILF 232
V LR+ + + G+ V ++IPFQ QA W +G + + + GD + L
Sbjct: 167 VTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLC 226
Query: 233 IRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQ 291
+ SA R D G+Y +T+R E +A + + VI+KP PP + + D L+W PP+
Sbjct: 227 LPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPR 286
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLER-YHPTTCTISDLIIGNSYSFRV 340
D G + Y+V++ W V E TT T + + G Y+FRV
Sbjct: 287 DNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRV 336
Score = 78.2 bits (191), Expect = 2e-14
Identities = 105/417 (25%), Positives = 159/417 (38%), Gaps = 34/417 (8%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P+ + D + V + W PP G ++ YV+E + G S W+ V P T
Sbjct: 262 DPPQGPM--EVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADST 319
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAG----PPAMLDQPIHIRENIEAPKIRVPRH----L 180
T ++ G K+ RV AV+S GAG +L P + + AP I L
Sbjct: 320 TFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQGITL 379
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRTGDQDSILFIRSAQRS 239
T R G L + + K TWT N + +R ++ Q R +
Sbjct: 380 TWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVA 439
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
SG E + AV + PG ++++ D + L W P E
Sbjct: 440 PSGPGE-----PGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQ 494
Query: 300 GYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKEL 358
GY+V+ + QW P TT T L G Y RV + N G S + +
Sbjct: 495 GYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALD--- 551
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
+Q + PK + D S T + D P S A P P++ W+K+
Sbjct: 552 TLVQAMPVTVCPKFLV--DSSTKDLLTVKVGDTVRVP-------VSFEAMPMPEVTWLKD 602
Query: 419 KMEIQGNPKYR-ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG-EASVDCRLEVKA 473
+ + PK +++ G+ L I DSG+YT + G E + R+ V A
Sbjct: 603 GLPL---PKRSVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRVAA 656
>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
Length = 1326
Score = 186 bits (473), Expect = 3e-47
Identities = 126/423 (29%), Positives = 190/423 (44%), Gaps = 10/423 (2%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P P++S K P P P L + D S+SS++++W P GY+LE+
Sbjct: 887 PSVPSSSVVAKDPVKP----PGLVQDLHVSDSSNSSISLAWREPAEGD--PPSGYILEMR 940
Query: 111 REGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
E EW + P+ T TV L K+ R+ AV+ AG G P LD+ +
Sbjct: 941 AEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPA 1000
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
APK + L+ + + G + + F G P P W +G + ++ +
Sbjct: 1001 APKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVPTKGRETITKSKNHSQF 1060
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I S +RSDSG Y + ++ E EA+ I + V + P PP+++RL + L W
Sbjct: 1061 L-INSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHS 1119
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS- 349
D Y++ K D T W+T ER T++ L+ G Y FRV + N G S
Sbjct: 1120 PDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSE 1179
Query: 350 -TSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
+ T + Q D++AK K + ++D+ AP F PL HT G + C+ +
Sbjct: 1180 PLDSRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGN 1239
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P+P + K + I N K+ S GVCTL I + DSG Y+ N LG+ C
Sbjct: 1240 PRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCT 1299
Query: 469 LEV 471
L V
Sbjct: 1300 LTV 1302
Score = 85.9 bits (211), Expect = 7e-17
Identities = 47/166 (28%), Positives = 88/166 (53%), Gaps = 3/166 (1%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNG-HALDSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
+VG T ++++PF+GKP P+ TW +G + +RVSM G+ ++L I + R DSG
Sbjct: 620 KVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLIL 679
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L ++ + A A + + V+++P PP + L++ G ++W P+D G + ++V+
Sbjct: 680 LKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVE 739
Query: 305 KADKKTGQWFTVLE-RYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
+ W + E T + + + G +Y FR+ + N G+S
Sbjct: 740 RRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVS 785
Score = 63.5 bits (153), Expect = 4e-10
Identities = 98/476 (20%), Positives = 162/476 (34%), Gaps = 49/476 (10%)
Query: 15 EETASESAKVPTAEPPGEVAVSESTREE------QVPKPQAPAPQAPTASTATKPAPPSE 68
E T E + E + +S RE+ ++ A S +P PP
Sbjct: 647 EVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQG 706
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
V L S S V + W+ P+ G + +++E G W+ + VT
Sbjct: 707 RVEFLEL-------SGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ + G + R+ AV+S G P ++ + IE P + V
Sbjct: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEE-VFAGNPIEPPGFASQPQVTDVTKEAV 818
Query: 189 GETVNLQIPFQGKP----------KPQATWTH-NGHALDSQRVSMRTGDQDSILFIRSAQ 237
T N G P K W N + + ++ +D+ R
Sbjct: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878
Query: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
+ +G + +V + AK ++ PG + + D + +L W P +
Sbjct: 879 VNKAGPGQPSVPSSSVVAKD-----PVKPPGLVQDLHVSDSSNSSISLAWREPAEGDPPS 933
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTSATVTK 356
GY+++ + T +W + TC T+ LI Y FR+ + N G+
Sbjct: 934 --GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVG------- 984
Query: 357 ELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADH-TSTPGYSTQLFCSVRASPKPKIIW 415
E + K A P + D S L H G + + + SP P +IW
Sbjct: 985 EPVELDKGVRAMPPPAAPKFDLSAR------LKSHMVVRAGTALCIHAAFSGSPPPDVIW 1038
Query: 416 MKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
K+ + +G + K S DSGVY N GEA D + V
Sbjct: 1039 QKDGVPTKGRETITKSKNHSQFLINSTKRS--DSGVYRILLQNEFGEARYDIHVRV 1092
Score = 36.6 bits (83), Expect = 0.051
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Query: 382 PSFTQPLADHTSTP--GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
PS + LA H T G++ + R P PK+ W K+ ME+ + + L
Sbjct: 606 PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALL 665
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
I DSG+ K N G A+ L V
Sbjct: 666 TISNCVREDSGLILLKLKNDHGSATATLHLSV 697
Score = 31.6 bits (70), Expect = 1.7
Identities = 74/346 (21%), Positives = 126/346 (36%), Gaps = 55/346 (15%)
Query: 137 LGDKFLLRVSAVSSAGAGPPAM-------------LDQPIHIRENIEAPKIRVPRHLRQT 183
+G K++L +S V+ AG ++ LD+P+ ++ K+ RQT
Sbjct: 289 MGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTE----RQT 344
Query: 184 YIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTGDQDSILFIRSAQRSD 240
+ ++ + K +P W NG L D +++ L I+ A+ SD
Sbjct: 345 AVFEIRLS---------KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395
Query: 241 SGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
SG + +A+ ID + I+ ++R+ + A L+ EL
Sbjct: 396 SGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKE--RSRACLE---------CELTS 444
Query: 301 YMVQKADKKTGQWFTVLERYHPT-TCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELA 359
V KK GQ +Y ++LII ++ LS T +
Sbjct: 445 KDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQ-----------LSDGGEYT--VV 491
Query: 360 HIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK 419
+Q D I + ++D + G +L C V K + +W+K+
Sbjct: 492 AMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDG 550
Query: 420 MEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
EI P + + + V L P G YT +A EASV
Sbjct: 551 KEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASV 596
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 155 bits (392), Expect = 8e-38
Identities = 92/303 (30%), Positives = 156/303 (51%), Gaps = 15/303 (4%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
PA A + + +P PP + +TL DV+ +SV++SWE PE G + GY++E+
Sbjct: 22036 PAETAESVKASERPLPPGK--------ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 22087
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
+G+ +W + + VT+ T+ L G+++ RVSA + G P L P+ ++ +
Sbjct: 22088 QTKGSDKWATCAT--VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 22145
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQD 228
P ++ L T+ GE + + +PF G+P P TW + L + RV+ + + +
Sbjct: 22146 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 22202
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQW 287
S+L I+ A R D G Y + + EA ++++V++KPGPP+ +++ +V + L W
Sbjct: 22203 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 22262
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G + + Y+V+K D T W V TT L G Y FR+ +EN G
Sbjct: 22263 GPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYG 22322
Query: 348 LST 350
ST
Sbjct: 22323 KST 22325
Score = 155 bits (392), Expect = 8e-38
Identities = 92/291 (31%), Positives = 146/291 (50%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A + + PS P +TL DVS +S ++ WE PE G + GYV+E+ +G +W V
Sbjct: 24203 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 24262
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ V V L+ G ++ RV A + G P +L P+ ++ P +++P +
Sbjct: 24263 AESK--VCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN- 24319
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
TY Q GE + ++IP G+P+P +W +G L + RV++ ++L I+ +
Sbjct: 24320 --TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKD 24377
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTEL 298
D G+Y +T A + ++V+EKPGPP +R +V + W PP TG ++
Sbjct: 24378 DFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQI 24437
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+V+K D T W V TT I+ L G Y FR+F+EN G S
Sbjct: 24438 SNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 24488
Score = 155 bits (392), Expect = 8e-38
Identities = 96/325 (29%), Positives = 162/325 (49%), Gaps = 9/325 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR-PMMV 127
D P P + + D + SS+T+ W P G + GYV+E+ + EW VS + +
Sbjct: 27165 DPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRT 27224
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ V NL G + RVSAV+ AG G P +++P+ ++ +EAP+I + LR + I +
Sbjct: 27225 TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAK 27284
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRSDSGRYEL 246
GE V + IPF+G+P P TW + L S R S+ D S+L I R+D+G+Y L
Sbjct: 27285 AGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYIL 27344
Query: 247 TVRVEDLEAK-AVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
T+ E K + + + V++ P +++ V L W PP G + ++ Y+++K
Sbjct: 27345 TIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEK 27404
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
D W V + T+ + DL + FRV +EN G+ T+ ++ A+
Sbjct: 27405 RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP---VKAAE 27461
Query: 366 IAAKPKGFIERDFSEAP---SFTQP 387
+ A + +D ++ S+T+P
Sbjct: 27462 VPAPIRDLSMKDSTKTSVILSWTKP 27486
Score = 154 bits (389), Expect = 2e-37
Identities = 121/445 (27%), Positives = 189/445 (42%), Gaps = 28/445 (6%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V KP A P A +P+PP LT D + SSV + WEPP + G +
Sbjct: 13273 VGKPSAATPFVKVADPIERPSPPVN--------LTSSDQTQSSVQLKWEPPLKDGGSPIL 13324
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
GY++E C EG W+ + + + V L G+K+L RVSA + AG P+ + P+
Sbjct: 13325 GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPL 13384
Query: 164 HIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSM 222
+ P + + + V + + +P G P+P ATW L++ RV M
Sbjct: 13385 TADDAFVEPTMDLSAFKDGLEVI-VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKM 13443
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
+T + L I ++RSD G Y L + ID+ VI +P P ++ D+ +
Sbjct: 13444 KTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDS 13503
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP D G + L GY+V+K + W V++ T+ DL+ G Y F+V +
Sbjct: 13504 VHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCA 13563
Query: 343 ENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
N CG A V + + A + P+ RD + F D G S
Sbjct: 13564 RNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL--TWDPPKNDGGSRIKG 13621
Query: 403 CSVRASPKPKIIWM-------KNKMEIQGNP-------KYRALSEQGVCTLEIRKPSPFD 448
V P+ W+ + KME+ G + +AL+ QG + +P+
Sbjct: 13622 YIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS--KPSRPTEEI 13679
Query: 449 SGVYTCKAINVLGEASVDCRLEVKA 473
V T +A + + + L VKA
Sbjct: 13680 QAVDTQEAPEIFLDVKLLAGLTVKA 13704
Score = 154 bits (388), Expect = 2e-37
Identities = 82/278 (29%), Positives = 141/278 (50%), Gaps = 1/278 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P ++ + D S ++V++ W P G + + GY++E+C+ +W V+A + T+
Sbjct: 28254 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRY 28313
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV +L G+++ RVSA++ AG G + I + + AP++ + + +QT++ + G
Sbjct: 28314 TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGA 28373
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
++ L I +QG+P P A W+ L S R + T D S L + + R+D+G+Y LTV
Sbjct: 28374 SIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVEN 28432
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
+ V++ PGPP I DV +A L W P G + Y+V+K +
Sbjct: 28433 NSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASR 28492
Query: 311 GQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
W + E+ ++DL G Y FRV + N G+
Sbjct: 28493 RSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGV 28530
Score = 153 bits (386), Expect = 4e-37
Identities = 88/291 (30%), Positives = 151/291 (51%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE P P +TL DV+ ++ T+ WE PE G + GYV+E+ +G+ +W
Sbjct: 25287 TEPVKVSEP-PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-- 25343
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + T+ L G++++ RV+AV+ G P L P+ R+ P + +P H
Sbjct: 25344 TCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH- 25402
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
T+ + E + + +PF+G+P+ W +G L ++ RV++ + + L I+ A +
Sbjct: 25403 --TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKE 25460
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
D G YEL V I I+V+++PGPP IR+ +V + + W PP+ G ++
Sbjct: 25461 DVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQIS 25520
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
Y+V+K + + W V + T+ I L G+ Y FRV +EN G S+
Sbjct: 25521 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSS 25571
Score = 152 bits (384), Expect = 6e-37
Identities = 89/283 (31%), Positives = 147/283 (51%), Gaps = 7/283 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
+VP P +T+DDV+ +SV++SW PE G + Y++E+ + + +W + +
Sbjct: 23129 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSL-- 23186
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
Q + NL G+++L RV AV+ G P L PI ++ + P ++ +Y QV
Sbjct: 23187 QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF---SSYSVQV 23243
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + +++P G+PKP TWT +G L + R+++ + L I+ + D G+Y +T
Sbjct: 23244 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 23303
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
V + A I+I+ ++KP PP ++ DV + L W PP TG ++ Y+VQK
Sbjct: 23304 VANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKR 23363
Query: 307 DKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D T W V TT ++ L G Y FR+F+EN G S
Sbjct: 23364 DTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 23406
Score = 149 bits (375), Expect = 7e-36
Identities = 90/292 (30%), Positives = 144/292 (49%), Gaps = 2/292 (0%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A +VP P L + DV+ S+VT++WE P G L GYVLE C+ G W+ V
Sbjct: 29625 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 29684
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
V + TV +L G+++L R+ A + G P + +++ P I +
Sbjct: 29685 VTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 29744
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++T G V L IP G+P P A+W G L +S+RV++ T + + L IR
Sbjct: 29745 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 29804
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G Y L ++ I +++++KPGPP+ I++ ++ + + W PP+ G L
Sbjct: 29805 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 29864
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
GY+V++ D W V E +T + L GN Y FRV + N G+ +
Sbjct: 29865 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 29916
Score = 145 bits (367), Expect = 6e-35
Identities = 109/371 (29%), Positives = 175/371 (47%), Gaps = 16/371 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE PS P L + D++ S+V+++W P+ G + GYV+E R+G+ +W +
Sbjct: 20956 TEPVKASE-APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 21014
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + VRNL G+++ +V AV+SAG P +P+ ++E P++ +
Sbjct: 21015 TT--VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTMLPELDLRGIY 21071
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++ I + G+ + ++IP G+PKP TW L +QRV+ T +IL I RS
Sbjct: 21072 QKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRS 21131
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
DSG Y LT R E VI I V + PGPP+ I+ +V W PP++ G +
Sbjct: 21132 DSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 21191
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y+V+ + W + TT + L G Y FRV ++N G+ TSA +
Sbjct: 21192 SNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIV 21251
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ +D S S+ +PL+D G S L V + I+W
Sbjct: 21252 ANYPFKVPGPPGTPQVTAVTKD-SMTISWHEPLSD-----GGSPILGYHVERKERNGILW 21305
Query: 416 MK-NKMEIQGN 425
+K + GN
Sbjct: 21306 QTVSKALVPGN 21316
Score = 145 bits (366), Expect = 8e-35
Identities = 94/331 (28%), Positives = 158/331 (47%), Gaps = 19/331 (5%)
Query: 49 APAPQAP---TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
AP+P +P T KP PP P +L D S SS++++W P G + GY
Sbjct: 21739 APSPTSPFYKACDTVFKPGPPGN-----PRVL---DTSRSSISIAWNKPIYDGGSEITGY 21790
Query: 106 VLELCREGASEW-VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E+ EW + + T T+ L ++ +R+ A++S G G PA++
Sbjct: 21791 MVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 21850
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMR 223
+ + P+I + LR+ + T+ L +P +G+P P+ W +G +LD + S+
Sbjct: 21851 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 21908
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ ++L + + R DSG+Y LTV A +++ V++ PGPP +++ +V +
Sbjct: 21909 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 21968
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L W PP G +++ Y+V+K + + TV H T+ + L G SY FRV +E
Sbjct: 21969 TLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAE 22028
Query: 344 NLCGLSTSATVTKELAHIQKADIAAKPKGFI 374
N G+ A E A KA P G I
Sbjct: 22029 NEYGIGLPA----ETAESVKASERPLPPGKI 22055
Score = 144 bits (362), Expect = 2e-34
Identities = 86/282 (30%), Positives = 140/282 (49%), Gaps = 4/282 (1%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P L + +V+ ++VT++W PP+ G + YVLE G ++ V+ ++ +
Sbjct: 16716 VPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 16775
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV+ L GD + RVSAV+ G G P+ +PI ++ + P + + R +VG
Sbjct: 16776 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL--DFRDKLTIRVG 16833
Query: 190 ETVNLQIPFQGKPKPQATW-THNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
E L + GKPKP+ +W L+ R ++T L A+RSDSG+Y + V
Sbjct: 16834 EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV 16893
Query: 249 RVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
K + V+++PGPP + +V + W PP D G +++ Y+++K +
Sbjct: 16894 ENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKE 16953
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
W V TTC +S L+ G Y FR+ +ENL G+S
Sbjct: 16954 VGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGIS 16995
Score = 144 bits (362), Expect = 2e-34
Identities = 84/305 (27%), Positives = 146/305 (47%), Gaps = 10/305 (3%)
Query: 54 APTASTATKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A A + KP+ PS+ + P P + D + +SV+++W PE G + GY
Sbjct: 30008 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 30067
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165
++E+ + EW + P + + T+ +L G ++ RV A ++ G G PA + + +
Sbjct: 30068 LIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 30127
Query: 166 RENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG 225
E +E P + ++ + G + L IP +GKP P WT G + S+R + T
Sbjct: 30128 TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI-SKRAMIATS 30186
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
+ + L I+ A R DSG Y+L + + + I + VI P P + D+ +
Sbjct: 30187 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR 30246
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
+ W PP D G ++LGY++++ + W+T+ R T+ + L Y FRV +EN
Sbjct: 30247 VSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 30306
Query: 345 LCGLS 349
G+S
Sbjct: 30307 QFGIS 30311
Score = 140 bits (354), Expect = 2e-33
Identities = 81/280 (28%), Positives = 142/280 (50%), Gaps = 2/280 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P + D +++S+ ++W+PP+ G ++GY++E C G+ +WV P+ T+
Sbjct: 13587 VPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETK 13645
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
V L G + RV A++ GA P+ + I + EAP+I + L + G
Sbjct: 13646 MEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAG 13705
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
+ L GKP+P+ TWT L +R+++ + S + I ++RSD+G Y +
Sbjct: 13706 TKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEA 13765
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
A AV+++ V++KPGPP++ + DV + L W PP+D G +++ Y+V++
Sbjct: 13766 VNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRAT 13825
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ W + T + LI Y FRV +EN+ G+
Sbjct: 13826 DSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGV 13865
Score = 140 bits (354), Expect = 2e-33
Identities = 91/313 (29%), Positives = 146/313 (46%), Gaps = 9/313 (2%)
Query: 54 APTASTATKPAPPSEDV-------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYV 106
A A+ K +PPS+ P P + + D SS+++ + WEPP G + GY
Sbjct: 14978 AENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYF 15037
Query: 107 LELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR 166
++ G +EW + + + V Q TV+ + G + LRVSAV++AG GPP QP+ +
Sbjct: 15038 VDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVA 15096
Query: 167 ENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGD 226
E E P + + ++ G+T+ + G+P P WT LD RV +
Sbjct: 15097 EPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVG 15156
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
S L I+ A R D GRY +T A + V + PGP ++ + L
Sbjct: 15157 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 15216
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W+ P+D G +E+ G+++++ D K W +E + C I+ L+ G Y FRV ++N
Sbjct: 15217 WSDPEDDGGSEITGFIIERKDAKMHTWRQPIET-ERSKCDITGLLEGQEYKFRVIAKNKF 15275
Query: 347 GLSTSATVTKELA 359
G + LA
Sbjct: 15276 GCGPPVEIGPILA 15288
Score = 140 bits (353), Expect = 3e-33
Identities = 88/305 (28%), Positives = 147/305 (48%), Gaps = 7/305 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
TK + PS P L + +S SV+++W PE G + YV+E +G WV
Sbjct: 26365 TKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC 26424
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ T V L ++ RV A + AG P L P+ I+E +E P+I +
Sbjct: 26425 AVAKS--THHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFP 26482
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRS 239
T + G + + IP GKP P+ T + +G L + R + ++ + ++ + +
Sbjct: 26483 SHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA 26542
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+GRYE+T KA I+I+V+++PGPP+ + + D+ + L+W PP+ G +++
Sbjct: 26543 DAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQV 26602
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y++ K + T W V T + L G Y FR+ +EN G+S SA VT
Sbjct: 26603 TNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVT 26662
Query: 356 KELAH 360
+L +
Sbjct: 26663 VKLPY 26667
Score = 139 bits (351), Expect = 4e-33
Identities = 86/300 (28%), Positives = 149/300 (49%), Gaps = 6/300 (2%)
Query: 61 TKPAPPSED---VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEW 117
T P +ED +PS P + D +++T++W P G + GY +E + ++W
Sbjct: 26071 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 26130
Query: 118 VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVP 177
S + + T+ T+ L G +++ RV +V+ GA P+ P +E E P +
Sbjct: 26131 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 26189
Query: 178 RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQ 237
+R+T I + G + + +PF+G+P P W+ L + R + T D + L I +A
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENAN 26248
Query: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
R+DSG+Y LT++ A + + V++ PGPP++I + DV +A L W P++ G
Sbjct: 26249 RNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAP 26308
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
+ Y ++K + W +V + + +++L G Y FRV EN G+ A TKE
Sbjct: 26309 VKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKE 26367
Score = 138 bits (347), Expect = 1e-32
Identities = 87/299 (29%), Positives = 144/299 (48%), Gaps = 14/299 (4%)
Query: 61 TKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+ PSE D P P+ L +++ +VT+ W PE G + Y++E
Sbjct: 21342 SKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDL 21398
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEA 171
W+ + ++ + TV L + RV A ++AGA PP+ I R+++EA
Sbjct: 21399 PNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEA 21458
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSI 230
PKI+V + T I + GE L+ G+P P W+ +G L+ + ++ ++ D +
Sbjct: 21459 PKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN 21518
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTP 289
L + + R DSG Y LT AK + ++ V+++PGPP + + +V L W P
Sbjct: 21519 LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 21578
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P D G ++ Y+VQK + W V T ++ L+ GN Y FRV + N G+
Sbjct: 21579 PLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 21637
Score = 138 bits (347), Expect = 1e-32
Identities = 86/314 (27%), Positives = 145/314 (46%), Gaps = 10/314 (3%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V +P P+ P PPS + D S SSV+++W P G ++
Sbjct: 24984 VGEPSEPSVFYRACDALYPPGPPSNP--------KVTDTSRSSVSLAWSKPIYDGGAPVK 25035
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
GYV+E+ A EW + + +Q TV L ++ R+ A++S G G PA L
Sbjct: 25036 GYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 25095
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM 222
+ +E IE P+I + LR+ + + T+ L + +G+P+P+ W + + R +
Sbjct: 25096 VVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKW-EKAEGILTDRAQI 25154
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
++L I + R DSGRY LT+ A +++ V++ P P ++ + +V +
Sbjct: 25155 EVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDS 25214
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP G ++ Y+V+K + + T+ TT I +L G SY FRV +
Sbjct: 25215 VTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 25274
Query: 343 ENLCGLSTSATVTK 356
N G+ A T+
Sbjct: 25275 SNEYGIGLPAETTE 25288
Score = 137 bits (344), Expect = 3e-32
Identities = 85/320 (26%), Positives = 153/320 (47%), Gaps = 10/320 (3%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P + S K A PS P + D + S +++W P G L + GYV+E +
Sbjct: 20657 PSEASDSVLMKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 20713
Query: 112 EGASEWVP-VSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G W+ + + +TQ V +L +K+ R+SA++ AG G PA++ + I E
Sbjct: 20714 VGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREM 20772
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
AP + LR+T + + G ++ + +P +G+P P+ TWT + L + R ++ + ++
Sbjct: 20773 APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN-RANIENTESFTL 20831
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I R D+G++ +T+ + +++ V++ PGP ++R D+ + L W P
Sbjct: 20832 LIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLP 20891
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
G + + Y+V+K + + T + H T ++ L G Y FRV +EN G+
Sbjct: 20892 LIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 20951
Query: 351 SATVTKELAHIQKADIAAKP 370
T+ + KA A P
Sbjct: 20952 PTETTEPV----KASEAPSP 20967
Score = 135 bits (340), Expect = 8e-32
Identities = 87/319 (27%), Positives = 146/319 (45%), Gaps = 11/319 (3%)
Query: 63 PAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P+PPS+ V PS P+ D + +SV ++W+PP G + GY++E + G
Sbjct: 17097 PSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGD 17156
Query: 115 SEWVPVSARPMMV--TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
EW + P T+ V L G + RV AV++AG PA + +P+ +++ +E P
Sbjct: 17157 EEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPP 17216
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
++ + ++ + +VG+T+ L +G P P+ TW + + + S L
Sbjct: 17217 ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT-KARIDVTPVGSKLE 17275
Query: 233 IRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
IR+A D G Y LTV + +LV++KPGPP + + ++ + L W P D
Sbjct: 17276 IRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLD 17335
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
G + + Y+V++ D + QW + + L GN Y FRV +EN G
Sbjct: 17336 DGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFV 17395
Query: 353 TVTKELAHIQKADIAAKPK 371
K + + PK
Sbjct: 17396 ETPKPIKALDPLHPPGPPK 17414
Score = 135 bits (340), Expect = 8e-32
Identities = 83/299 (27%), Positives = 153/299 (51%), Gaps = 2/299 (0%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ++ A + P P + D + SSV++SW P G + GY++E+ R
Sbjct: 19570 PGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKR 19629
Query: 112 EGASEWVPVSA-RPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
+ WV + + + T+ V L ++ RV AV+ G P+ + + ++ +
Sbjct: 19630 ADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 19689
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRTGDQDS 229
P+ + LR+T I + G T+ L +P +G+P P+ TW+ N + D + +++ D D+
Sbjct: 19690 PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDT 19749
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L + + D+G+Y LT+ + + I + V++ PGPP ++ + ++ +A + W P
Sbjct: 19750 FLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEP 19809
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P G + ++ Y+VQK D + W TV T+ +++L G SY FRVF+EN G+
Sbjct: 19810 PIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGI 19868
Score = 134 bits (338), Expect = 1e-31
Identities = 85/299 (28%), Positives = 151/299 (50%), Gaps = 10/299 (3%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P PT + + P P PS PL L + D + ++W+PPE+ G + GY +E+C
Sbjct: 14269 PSEPTEILSIEDPTSP----PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMC 14324
Query: 111 REGASEWVPVSARPMMVTQQTVRNLALGDK-FLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
G +W+ V++RP+ + V + DK ++LRV AV++ G P+ + + + ++
Sbjct: 14325 PVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPD 14384
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQD 228
P I + H I GE +++ +PF+ P P +W +G + S R++M+
Sbjct: 14385 CKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS 14441
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+ L + + R+D+G Y +T+ + A A I++ VI PGP I+ D+ + L W
Sbjct: 14442 AHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWE 14501
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G T +L Y++++ + + V+ + + T+ DLI Y FRV + N G
Sbjct: 14502 PPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG 14560
Score = 134 bits (338), Expect = 1e-31
Identities = 86/307 (28%), Positives = 140/307 (45%), Gaps = 11/307 (3%)
Query: 46 KPQAPAPQAPTAS-TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQG 104
K + P PT TA P P P P ++ DV+ S+V++ W P+ G + G
Sbjct: 19171 KAGSSPPSKPTEYVTARMPVDP----PGKPEVI---DVTKSTVSLIWARPKHDGGSKIIG 19223
Query: 105 YVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK--FLLRVSAVSSAGAGPPAMLDQP 162
Y +E C+ +WV + P + Q+ L +K + R A ++ PP+ P
Sbjct: 19224 YFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 19283
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVS 221
+ I P+I + ++ + G V L GKP P +W +G L ++ +
Sbjct: 19284 VTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK 19343
Query: 222 MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGC 281
M L + S R DSG Y +T A I + V++KPGPP+S+++ ++
Sbjct: 19344 MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSD 19403
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
A L W PP + G +E+ Y+V K + W V T+C++ LI G+ Y FR+
Sbjct: 19404 RAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRIC 19463
Query: 342 SENLCGL 348
+EN G+
Sbjct: 19464 AENKYGV 19470
Score = 134 bits (337), Expect = 2e-31
Identities = 111/426 (26%), Positives = 182/426 (42%), Gaps = 23/426 (5%)
Query: 48 QAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVL 107
+ P + P A P P P P L DV + V++ W P+R G + GY++
Sbjct: 17391 RGPFVETPKPIKALDPLHP----PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 17446
Query: 108 ELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E EG +W+ + + + V L G + RV A + G G P PI +E
Sbjct: 17447 EYQEEGTQDWIKF--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 17503
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSMRTGD 226
+ P + + L + + + G TV +G P P A WT +G + + + ++ T +
Sbjct: 17504 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 17563
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
S+L I++ R D+G Y++TV + + V++ PGPP+ I +LDV + +
Sbjct: 17564 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 17623
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W PP+D G + ++ Y+V+K D + W V T I L G Y FRV +EN
Sbjct: 17624 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 17683
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE---APSFTQPLADHTS-TPGY---- 397
G+ T +A K + P + D +E S+T P +D S GY
Sbjct: 17684 IGVGPPLDSTPTVAK-HKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 17742
Query: 398 --STQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
T + V +P + + + ++R +E + KPSP + C+
Sbjct: 17743 REVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 17799
Query: 456 AINVLG 461
I G
Sbjct: 17800 PIKPPG 17805
Score = 133 bits (335), Expect = 3e-31
Identities = 99/424 (23%), Positives = 187/424 (44%), Gaps = 20/424 (4%)
Query: 41 EEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRL 100
E +V A P+ +T A P P + D + +S+T++W P G
Sbjct: 23890 EFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGS 23949
Query: 101 GLQGYVLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAML 159
+ GYV+E+C+ EW V+ + + VT+ + L ++ +RV A++ G G +
Sbjct: 23950 EILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV 24009
Query: 160 DQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
+ + +EAP++ + LR+ + + G + + IPF+G+P P+ TW+ + +
Sbjct: 24010 PGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDK 24068
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
V + G + L I + R+D+G+Y L + A + + V++ PGPP ++ + +V
Sbjct: 24069 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 24128
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR 339
+A L W PP G ++ Y++ K + + V + T+ + +L G Y FR
Sbjct: 24129 KDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFR 24188
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
V +EN G+ V E KA P G + L D + T ++
Sbjct: 24189 VMAENEFGVG----VPVETVDAVKAAEPPSPPGKV------------TLTDVSQTS--AS 24230
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
++ +++ +M+ +G K+ ++E VC + S + KA N
Sbjct: 24231 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNE 24290
Query: 460 LGEA 463
G++
Sbjct: 24291 KGKS 24294
Score = 132 bits (332), Expect = 7e-31
Identities = 74/289 (25%), Positives = 139/289 (48%), Gaps = 11/289 (3%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT-- 128
P P + D + SS+++ W+PP + G ++GY++E+ EG ++W V+ ++T
Sbjct: 15705 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 15764
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ V NL K+ RV AV+ AG P+ I + E P++ + + + +
Sbjct: 15765 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 15824
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR---------VSMRTGDQDSILFIRSAQRS 239
G + + +G+P P+++W +G A + + + T + S++ I +RS
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
+G+Y +T + + + A + V++ PGPP +++ D+ + L W P D G +
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIK 15944
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
GY+++K W V TT + DL+ Y FRV +EN G+
Sbjct: 15945 GYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 15993
Score = 132 bits (332), Expect = 7e-31
Identities = 84/317 (26%), Positives = 143/317 (45%), Gaps = 3/317 (0%)
Query: 57 ASTATKPAPPSEDV-PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
AS + PA + + P P + D + SS + W PP + G + GY++E EG
Sbjct: 16406 ASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKE 16465
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIR 175
EW + + T+ V L G + RV AV+ AG G P + I +++ + +P ++
Sbjct: 16466 EWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQ 16525
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRS 235
+ +R + G + + GKP P TW N L Q ++ T S + I++
Sbjct: 16526 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL-PQEATIETTAISSSMVIKN 16584
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTG 294
QRS G Y L + E E K I + V++ PGP + L ++ + L W P+D G
Sbjct: 16585 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 16644
Query: 295 NTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATV 354
+ + Y+++K + W V T+ LI G +Y FR+ +EN G+
Sbjct: 16645 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 16704
Query: 355 TKELAHIQKADIAAKPK 371
++ L + + +P+
Sbjct: 16705 SEALVIREPITVPERPE 16721
Score = 131 bits (329), Expect = 2e-30
Identities = 90/314 (28%), Positives = 138/314 (43%), Gaps = 14/314 (4%)
Query: 52 PQAPTASTATKPAPPSEDV--PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P PT KP S+ + P P L + +++ +S T++W PP R G + GY+
Sbjct: 18780 PGVPT--DVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSY 18837
Query: 110 CREG--ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E A W S + V L G K+ RV+A ++ G P + +E
Sbjct: 18838 REEEQPADRWTEYSV--VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE 18895
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHN-GHALDSQRVSMRTGD 226
+ PKI +P + + G+ + ++ GKP P W + S +++ D
Sbjct: 18896 QLLPPKILMPEQITI----KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 18951
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
SIL I+ R DSG Y LT I ++V++ PGPP + D+ +L
Sbjct: 18952 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 19011
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W P + G + + Y+V+K D G W T L T+C + LI G Y FRV +EN
Sbjct: 19012 SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 19071
Query: 346 CGLSTSATVTKELA 359
G+S T K +A
Sbjct: 19072 FGISEPLTSPKMVA 19085
Score = 131 bits (329), Expect = 2e-30
Identities = 83/309 (26%), Positives = 146/309 (47%), Gaps = 12/309 (3%)
Query: 46 KPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
+P P+ KP PP+ P ++ D++ SSV +SW P G +QGY
Sbjct: 22821 EPSPPSAYQKACDPIYKPGPPNN-----PKVI---DITRSSVFLSWSKPIYDGGCEIQGY 22872
Query: 106 VLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E C EW + + T V L ++ R+ A++ AG G A + PI
Sbjct: 22873 IVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPII 22932
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMR 223
+ E +EAP I + LR+ + G ++ L +P +G+P P+ W +G D+ + +
Sbjct: 22933 VEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT 22992
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ +L + R DSG+Y LT+ A + + V++ P PP ++++ ++ +
Sbjct: 22993 SSFTSLVL--DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 23050
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
++ W PP G +++ Y+V+K + + V+ H + I L G SY FRV +E
Sbjct: 23051 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 23110
Query: 344 NLCGLSTSA 352
N G+ A
Sbjct: 23111 NEYGIGLPA 23119
Score = 130 bits (326), Expect = 3e-30
Identities = 82/290 (28%), Positives = 144/290 (49%), Gaps = 7/290 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+ A + P + L + VS SS ++ W+ P G + GYV++ E ++W V
Sbjct: 19874 TRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKWQRV 19932
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ Q + ++L G ++ RVSA + G G P+ + + R+++ AP + +
Sbjct: 19933 MKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLP 19988
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRS 239
Y+ + L+IP +GKP P +W L + RVS+ + ++ L + Q+S
Sbjct: 19989 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 20048
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G+Y +T++ + I I V+ KPG P+ I+ +V L+W PP+D G +E+
Sbjct: 20049 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 20108
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Y+++K D +W T TT ++ L G Y+FRV +EN G+
Sbjct: 20109 TNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 20158
Score = 129 bits (325), Expect = 4e-30
Identities = 91/314 (28%), Positives = 152/314 (48%), Gaps = 15/314 (4%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P P+ K P P P P + D + S+T+ W P G + GYV+E+
Sbjct: 18481 PSLPSRPVVAKDPIEP----PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMR 18536
Query: 111 REGASE-----WVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ A W +A +V ++ TV +L ++ RV A + G G PA L + I
Sbjct: 18537 PKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 18596
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
+E +E P+I + +R+ I + G + L +G+P P+ TW G ++ +
Sbjct: 18597 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL 18656
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
D + L I ++ R DSG+Y LT+ E +++ V++ PGP S +++ DV +
Sbjct: 18657 VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCH 18716
Query: 285 LQWTPPQDTGNTELLGYMVQK--ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
+ W PP++ G +++ Y+V+K AD+KT W TV T+ +++L+ GN Y FRV +
Sbjct: 18717 VSWAPPENDGGSQVTHYIVEKREADRKT--WSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 18774
Query: 343 ENLCGLSTSATVTK 356
N G V K
Sbjct: 18775 VNEYGPGVPTDVPK 18788
Score = 124 bits (310), Expect = 2e-28
Identities = 78/279 (27%), Positives = 136/279 (48%), Gaps = 5/279 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV-TQ 129
PSAP ++ D + S++++W P G + GYVLE+ + +W V + T+
Sbjct: 29345 PSAPRVV---DTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 29401
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV +L +G K+ RV+AV+ G + I E IE P + + L++T + G
Sbjct: 29402 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAG 29461
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
++ L + G+P P TW+ G L S+ + + T + S+L + R D+G+Y +
Sbjct: 29462 ASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGKYTIEAE 29520
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ + A + + V + PGP S+++ +V + + W P G + Y+V+K +
Sbjct: 29521 NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAA 29580
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ TV + T IS L+ G Y FRV EN+ G+
Sbjct: 29581 MRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 29619
Score = 123 bits (309), Expect = 3e-28
Identities = 83/281 (29%), Positives = 129/281 (45%), Gaps = 4/281 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P+ P L + D S SS ++W P+ G + GY+LE+ ++G+ WV +
Sbjct: 28546 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTF-- 28603
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV L ++ RV A + AG P + I+E P + Q + G
Sbjct: 28604 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGS 28663
Query: 191 TVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ +P G+P P+ TW L ++ RVS+ T + L ++ + R DSGRY LT+
Sbjct: 28664 PFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLE 28723
Query: 250 VEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ ++VI +PGP + I + V + L W P+D G TE+ Y+V+K +
Sbjct: 28724 NTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRES 28783
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
T W V T ++ L YSFRV SEN G+S
Sbjct: 28784 GTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVS 28824
Score = 123 bits (308), Expect = 4e-28
Identities = 90/304 (29%), Positives = 137/304 (45%), Gaps = 10/304 (3%)
Query: 54 APTASTATKPAPPSE-----DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A+ KP+ PSE D P + + D+S +SV++SW+ P G + GY++E
Sbjct: 26746 AENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE 26805
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRE 167
W S + TQ + L ++ RV A ++ G+ P+ + PI +
Sbjct: 26806 RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCID 26865
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM--RTG 225
+ P I +P + + G +V L+ GKP P W + L + + T
Sbjct: 26866 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTT 26925
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
D SIL I+ A R +SG YEL +R A A I + +++KPGPP I V
Sbjct: 26926 DLASIL-IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKIT 26984
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L W PP D G ++ Y+V+K + W V E T + +I GN Y FRV + N
Sbjct: 26985 LLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVN 27044
Query: 345 LCGL 348
G+
Sbjct: 27045 KYGI 27048
Score = 122 bits (307), Expect = 5e-28
Identities = 110/421 (26%), Positives = 172/421 (40%), Gaps = 35/421 (8%)
Query: 67 SEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMM 126
S + P PL DD+ SV VSW PP G + GY+LE + W + +R +
Sbjct: 30227 SPNSPEGPL--EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VR 30283
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK--IRVPRHLRQT- 183
T V+ L ++ RVSA + G P ++P+ + + P+ P L T
Sbjct: 30284 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTK 30343
Query: 184 ------YIRQVGETVNLQIPFQGKPKPQAT--WT-HNGHALDSQRVSMRTGDQDSILFIR 234
+ R + + + + K +T W HN + + ++ D+ R
Sbjct: 30344 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 30403
Query: 235 SAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++D G E + E + K D KP P + +L + + LQW P+ G
Sbjct: 30404 IIAQNDVGLSETSPASEPVVCKDPFD-----KPSQPGELEILSISKDSVTLQWEKPECDG 30458
Query: 295 NTELLGYMVQKADKKTGQWF-TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
E+LGY V+ W + ER TI L+ Y FRVF+EN GLS
Sbjct: 30459 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 30518
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKI 413
+ K + + EAP + + D T+ G + QL C + P P I
Sbjct: 30519 TAMSI----KTKLTS----------GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 30564
Query: 414 IWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
W + E+ + KY+ S+ TL + D GVYTC A N +GE +L ++A
Sbjct: 30565 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 30624
Query: 474 S 474
+
Sbjct: 30625 T 30625
Score = 120 bits (300), Expect = 4e-27
Identities = 72/270 (26%), Positives = 126/270 (46%), Gaps = 3/270 (1%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V + +T+ W P G + GY++E W+ S ++ TQ TV L ++
Sbjct: 23532 VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRY 23591
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AGA P+ PI ++ +E P+I + R T + GET L+ G
Sbjct: 23592 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 23651
Query: 201 KPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W ++ S R ++ D ++L ++ A R D G+Y L +
Sbjct: 23652 KPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPV 23711
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP +++ V +L W+PP G +++ Y+V+K + W V
Sbjct: 23712 NVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVAS 23771
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ ++ L+ GN Y FR+ + N G+
Sbjct: 23772 EVVTNSLKVTKLLEGNEYVFRIMAVNKYGV 23801
Score = 117 bits (293), Expect = 2e-26
Identities = 77/312 (24%), Positives = 140/312 (44%), Gaps = 13/312 (4%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V+ +SVT+ W+ P G + GY++E W+ S ++ T V L ++
Sbjct: 22450 VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 22509
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AG P+ I R+ ++ P+I + + T + GE+ + G
Sbjct: 22510 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 22569
Query: 201 KPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W L ++ R+ +++ D + L ++ A R DSG Y L + E +
Sbjct: 22570 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 22629
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP + + V L W PP G ++++ Y+V++ + W V
Sbjct: 22630 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 22689
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
+C ++ L+ GN Y+FR+ + N G+ ++ + AK F+ D
Sbjct: 22690 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP---------LESEPVVAK-NPFVVPDA 22739
Query: 379 SEAPSFTQPLAD 390
+AP T D
Sbjct: 22740 PKAPEVTTVTKD 22751
Score = 116 bits (291), Expect = 4e-26
Identities = 77/322 (23%), Positives = 147/322 (45%), Gaps = 13/322 (4%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+P S+ + P P+ L D S + + W P G + GYV+E +
Sbjct: 17786 SKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKP 17845
Query: 113 GASEWVPVSARPMMVTQQTVR--NLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G ++W ++ + ++ Q R L G+++ R+ A + G G P L + + ++ +
Sbjct: 17846 GTAQWNRIN-KDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILH 17904
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
P++ + R +VG+T+ + +G+P+P TWT G L +RV +
Sbjct: 17905 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV 17964
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L I+ A R+D G+Y ++ + A+ + V+++PGP ++++ +V N + W
Sbjct: 17965 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWEN 18024
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
P D G +E+ ++V+ W V ++L+ N Y FRV +EN G+
Sbjct: 18025 PLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGVG 18083
Query: 350 TSATVTKELAHIQKADIAAKPK 371
+ + I D +P+
Sbjct: 18084 PTIETKTPILAINPIDRPGEPE 18105
Score = 116 bits (290), Expect = 5e-26
Identities = 83/297 (27%), Positives = 140/297 (47%), Gaps = 14/297 (4%)
Query: 62 KPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
KP+ PSE D P P ++ +++ +SVT+ W P+ G L GY++E
Sbjct: 20260 KPSLPSEPVVALDPIDPPGKPEVI---NITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLP 20316
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAP 172
+ W+ + + TV +L G K+ R+ A ++AGA P+ + I ++ EAP
Sbjct: 20317 SKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 20376
Query: 173 KIRVPRHLRQTYIRQVGETVNLQ-IPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSI 230
I + ++ + G+T+ L I GKP P+++W+ G + ++ T S+
Sbjct: 20377 TIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 20436
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I+ A R D+G Y +T + + V++ PGPP + + +V A L WTPP
Sbjct: 20437 LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP 20496
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
+ G + + Y+++K + W V E + LI GN Y FRV + N G
Sbjct: 20497 LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 20553
Score = 115 bits (288), Expect = 9e-26
Identities = 75/309 (24%), Positives = 133/309 (43%), Gaps = 36/309 (11%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P+ + + + ++ ++T++W+PP G + GY++E +G W + + +
Sbjct: 14580 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 14639
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T + L G ++ RV A ++AG P+ P + I+APK+ LR + + G+
Sbjct: 14640 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSLEVKRGD 14695
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG------------------------- 225
+ L G P P TW + + + + + R
Sbjct: 14696 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 14755
Query: 226 -----DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWG 280
+S L +R + R D G Y + V + AKA + V++ PGPP + D+
Sbjct: 14756 IDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRK 14815
Query: 281 CNAALQWTPPQDTGNTELLGYMVQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSF 338
+ +W PP D G +E++ Y ++K D K +W V +++ LI G Y F
Sbjct: 14816 TSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLF 14875
Query: 339 RVFSENLCG 347
RV +EN G
Sbjct: 14876 RVRAENRFG 14884
Score = 115 bits (287), Expect = 1e-25
Identities = 87/321 (27%), Positives = 145/321 (45%), Gaps = 17/321 (5%)
Query: 54 APTASTATKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A ++ + P+ PS+ D P P + DV+ ++T+ W PP R G + GY
Sbjct: 27833 AENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGY 27889
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIH 164
+E R+G WV + + Q TV L+ GD++ R+ A ++ G PP+ I
Sbjct: 27890 SIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIM 27948
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
R+ P + I + GE++ ++ QG+P P+ TW +G ++ +R++M
Sbjct: 27949 TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNMEI 28007
Query: 225 GDQ--DSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGC 281
D + LF+R A R G Y + + AKA I + V + PG IR ++ G
Sbjct: 28008 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 28067
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
L W P + G + Y+++K + W + ++ + T LI GN Y FRV
Sbjct: 28068 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 28127
Query: 342 SENLCGLSTSATVTKELAHIQ 362
+ N G+ +A IQ
Sbjct: 28128 AVNKFGVGRPLDSDPVVAQIQ 28148
Score = 114 bits (284), Expect = 3e-25
Identities = 81/305 (26%), Positives = 136/305 (44%), Gaps = 7/305 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L + D + V + W P+ G Y +E +G+ +W V + T
Sbjct: 18099 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 18158
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V + RV + G ++ + ++E+++ P + + L +
Sbjct: 18159 HYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVV-VKEDLQKPVLDLK--LSGVLTVKA 18215
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD---SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
G+T+ L+ +GKP P+ WT + A D S RV + T S + A+RSD G+Y
Sbjct: 18216 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 18275
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
+T A + V++KPGP +++++DV + W PP+D G E+ Y+++K
Sbjct: 18276 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEK 18335
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ K W T T++ LI GN Y FRV +EN G + T +K + K D
Sbjct: 18336 CETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG-TGPPTESKPVIAKTKYD 18394
Query: 366 IAAKP 370
+P
Sbjct: 18395 KPGRP 18399
Score = 114 bits (284), Expect = 3e-25
Identities = 73/298 (24%), Positives = 141/298 (47%), Gaps = 12/298 (4%)
Query: 58 STATKPAPPSE--DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
S + +P P + D P P + +++ SV++ W P G + GY++E
Sbjct: 25673 SKSCEPVPARDPCDPPGQP---EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDG 25729
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKI 174
W+ + + T V L ++ RV A ++A + P+ PI +++++E P++
Sbjct: 25730 RWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRV 25789
Query: 175 RVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFI 233
+ R + + GE + + G+P P +W +G ++ + R + + D ++L +
Sbjct: 25790 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 25849
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA---ALQWTPP 290
+ R D+G+Y LT++ ++ V++KPGPP+ L++ G A +L W P
Sbjct: 25850 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGP--LEINGLTAEKCSLSWGRP 25907
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Q+ G ++ Y+V+K + W T+C ++ L+ GN Y FRV N G+
Sbjct: 25908 QEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 25965
Score = 112 bits (279), Expect = 1e-24
Identities = 72/284 (25%), Positives = 129/284 (45%), Gaps = 7/284 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ ++VT+ W+ P G + GY++E W+ S ++ T
Sbjct: 24604 DPPGRPEAIV---ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLET 24660
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L ++ RV A ++AG P+ I R+ I+AP + + +
Sbjct: 24661 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 24720
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALD--SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
GET L+ +GKP P W+ +G L+ + R+ +++ Q + L ++ R+D G+Y
Sbjct: 24721 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L + I + V+++PGPP +++ V L W PP G + Y+++
Sbjct: 24781 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 24840
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
K + W V ++ L+ GN Y FRV + N G+
Sbjct: 24841 KRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 24884
Score = 107 bits (267), Expect = 2e-23
Identities = 103/376 (27%), Positives = 164/376 (43%), Gaps = 17/376 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P +E VP+ L++ D + +SV +SW P+ G + YV+E R+G E
Sbjct: 27454 TEPVKAAE-VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE--RKGKGEQTWS 27510
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
A + V L RV A + G P + PI ++E I P++ +
Sbjct: 27511 HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIP 27569
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++G V+L++P++GKPKP +W +G L +S+ V + L I++A++
Sbjct: 27570 GAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKE 27629
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS----IRLLDVWGCNAALQWTPPQDTGN 295
G+Y TV +++ + + I VI GPPS IR ++ + L W P+D G
Sbjct: 27630 HGGKY--TVILDNAVCRIAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 27686
Query: 296 TELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
E+ Y ++K + W V TT + +L+ Y FRV +EN G+S +
Sbjct: 27687 GEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSS 27746
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+A Q K I S+ S T D G S V + I+W
Sbjct: 27747 IIVAKHQFRIPGPPGKPVIYNVTSDGMSLTW---DAPVYDGGSEVTGFHVEKKERNSILW 27803
Query: 416 MK-NKMEIQGNPKYRA 430
K N I G +YRA
Sbjct: 27804 QKVNTSPISGR-EYRA 27818
Score = 107 bits (266), Expect = 3e-23
Identities = 88/337 (26%), Positives = 145/337 (43%), Gaps = 14/337 (4%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P++P LT + + S++T+ W+ P G +QGY++E R ++ V+ R T
Sbjct: 15295 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 15354
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVG 189
V NL + RV AV+ G P+ L + I+++ P I++ +R I+ + G
Sbjct: 15355 LVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAG 15413
Query: 190 ETVNLQIPFQGKPKPQATWTHN-------GHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
E V++ G P P+ W+ N AL + + + + L I A R D G
Sbjct: 15414 EPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKG 15473
Query: 243 RYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYM 302
Y +T + + V ++P PP ++ + D+ + L W P D G +E+ Y+
Sbjct: 15474 TYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 15533
Query: 303 VQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAH 360
+ K D +K +W V I LI Y FRV + N G+S K +
Sbjct: 15534 IDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 15593
Query: 361 --IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTP 395
+ KPK S S+T PL D+ +P
Sbjct: 15594 DPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSP 15629
Score = 107 bits (266), Expect = 3e-23
Identities = 81/313 (25%), Positives = 135/313 (43%), Gaps = 22/313 (7%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P + +TA P P P P+ L + ++ ++V +SW+PP+ G + Y++E
Sbjct: 15995 PPVETIQRTTARDPIYP----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC 16050
Query: 110 CREGAS-----EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ W + R + Q TV +L G ++ RV AV++AG P+ P
Sbjct: 16051 LAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCD 16110
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATW--------THNGHALD 216
+ P I L++ + G VN+ +G P P TW + L
Sbjct: 16111 CQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY 16166
Query: 217 SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRL 275
V+ D L I ++RSD+G Y +T A + + V+ +PGPP I+
Sbjct: 16167 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKF 16226
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
V L W PP+D G +++ Y+++K + W V T TI L+ G+
Sbjct: 16227 ESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHE 16286
Query: 336 YSFRVFSENLCGL 348
Y FR+ ++N G+
Sbjct: 16287 YVFRIMAQNKYGI 16299
Score = 105 bits (263), Expect = 7e-23
Identities = 89/333 (26%), Positives = 143/333 (42%), Gaps = 11/333 (3%)
Query: 23 KVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLD 80
KVP E +V E Q A AS A++P A D P P +
Sbjct: 28892 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP---EVT 28948
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLE---LCREGASEWVPVSARPMMVTQQTVRNLAL 137
DV+ S+V++ W P G + GY++E + G W+ + + TV L+
Sbjct: 28949 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 29008
Query: 138 GDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVGETVNLQ 195
GD + RV A ++AG + P+ R+ PK + L + + G + L
Sbjct: 29009 GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLD 29068
Query: 196 IPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLE 254
GKP+P+ WT LD ++VS++ + + I+ RSDSG+Y LTV+
Sbjct: 29069 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 29128
Query: 255 AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF 314
+ + V++ PGP + + V L W+ PQ+ G E+ Y+V++ + W
Sbjct: 29129 KAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV 29188
Query: 315 TVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
V + ++ LI N Y FRV + N G
Sbjct: 29189 IVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG 29221
Score = 102 bits (254), Expect = 8e-22
Identities = 105/421 (24%), Positives = 177/421 (42%), Gaps = 43/421 (10%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P LT+ V+ T++W P+ G + Y++E WV V ++
Sbjct: 29139 DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS 29198
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
R L ++++ RV AV+ G G P +PI R + P P + + +V
Sbjct: 29199 YVVTR-LIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPS---PPGIPE----EV 29249
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQ--------RVSMRTGDQDSILFIRSAQRSD 240
G I KP+ + + +D + RV+ D+ L + S
Sbjct: 29250 GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGC 29309
Query: 241 SGRYELTV-----RVEDLEAKAVIDILVIE-KPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++ +T E EA I PGPPS+ R++D + +L WT P G
Sbjct: 29310 DYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDG 29369
Query: 295 NTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
T+++GY+++ +K T QW+ V T T+ DL +G YSFRV + N+ G+S +
Sbjct: 29370 GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYS 29429
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
E+ +++ +I D A + + T G S +L SV P P
Sbjct: 29430 ESIAEIEPVERIEIP---------DLELADDLKKTV---TIRAGASLRLMVSVSGRPPPV 29477
Query: 413 IIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
I W K +++ RA+ + + L + K + +D+G YT +A N G+ S ++
Sbjct: 29478 ITWSKQGIDLAS----RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 29533
Query: 471 V 471
V
Sbjct: 29534 V 29534
Score = 100 bits (249), Expect = 3e-21
Identities = 105/423 (24%), Positives = 170/423 (40%), Gaps = 42/423 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DVSS TV W+PPE G +Q Y+LE C W SA ++
Sbjct: 18295 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSAT-VLTP 18353
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
TV L G++++ RV A + G GPP +P+ + + P P + T + +
Sbjct: 18354 GTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDKPGRPDPPEV--TKVSKE 18410
Query: 189 GETVNLQIP------------FQGKPKPQATWTH-NGHALDSQRVSMRTGDQDSILFIRS 235
TV P + K K W N A+ +R+ ++ ++L
Sbjct: 18411 EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQ-----NLLPDHE 18465
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
Q E+ + L ++ V+ IE PGPP++ R++D + L W P G
Sbjct: 18466 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGG 18525
Query: 296 TELLGYMVQK----ADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++GY+V+ AD + + + T++ L Y FRV ++N G+
Sbjct: 18526 APIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGI 18585
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
A + + A KPK +E + + + L G +LF VR
Sbjct: 18586 GRPAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGR 18633
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P PK+ W K ++ L + + L I + DSG Y+ +N GE +V
Sbjct: 18634 PAPKVTWRKVGIDNVVRKGQVDLVDT-MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 18692
Query: 469 LEV 471
+ V
Sbjct: 18693 VRV 18695
Score = 100 bits (248), Expect = 4e-21
Identities = 80/321 (24%), Positives = 140/321 (43%), Gaps = 21/321 (6%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ST D P P T+ DV +SV ++W PE G ++ YV+E+ +
Sbjct: 13965 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLK 14024
Query: 112 EGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEA 171
G EWV V A + TQ + L G ++ RV AV+ AG P+ P+ RE +
Sbjct: 14025 TGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 14083
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKP------------QATWTHNGHALDSQR 219
P PR L I + + +P + P + W + +
Sbjct: 14084 PS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTK 14141
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
++ + S+ R A + G+ + T +ED +V+ PGPP ++ ++DV
Sbjct: 14142 CTVTPLTEGSLYVFRVAAENAIGQSDYT-EIED----SVLAKDTFTTPGPPYALAVVDVT 14196
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSF 338
+ L+W PP++ G + Y+++K ++ +W + P ++D+I G F
Sbjct: 14197 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 14256
Query: 339 RVFSENLCGLSTSATVTKELA 359
+V +EN G+ + T+ L+
Sbjct: 14257 QVRAENEAGVGHPSEPTEILS 14277
Score = 97.1 bits (240), Expect = 3e-20
Identities = 80/302 (26%), Positives = 132/302 (43%), Gaps = 37/302 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L D++ +VT++W P+ G + GY +E +WV + P+ T
Sbjct: 13881 DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDT 13940
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V+ L K+ RV A + AG G P+ +PI I++ I+ P + ++ V
Sbjct: 13941 TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-----GKPTVKDV 13995
Query: 189 GETVNLQIPFQGKPKPQATWT---HNGHA-LDSQRVSM-RTGDQDSILFIRSAQRS---- 239
G+T + WT H+G A ++S + M +TG + + +
Sbjct: 13996 GKT-----------SVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLL 14044
Query: 240 ----DSGRYELTVRV-----EDLEAKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQW 287
+ Y VR E ++ +L EK P PP + ++++ A L+W
Sbjct: 14045 PGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKW 14104
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
T P+ G + + Y+V+K D + W TV T CT++ L G+ Y FRV +EN G
Sbjct: 14105 TVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIG 14164
Query: 348 LS 349
S
Sbjct: 14165 QS 14166
Score = 96.7 bits (239), Expect = 4e-20
Identities = 97/445 (21%), Positives = 172/445 (38%), Gaps = 86/445 (19%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP+ V + D++ SVT+ WEPP+ G + Y+L + W VS
Sbjct: 26569 RPGPPTGPV-------VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS 26621
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A + T V L G+++ R+ A + G I ++I++
Sbjct: 26622 AT-VARTMMKVMKLTTGEEYQFRIKAENRFG------------ISDHIDSA--------- 26659
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHN-----------------GHALDSQRVSMRT 224
V +++P+ P W N G A+ + M+
Sbjct: 26660 ---------CVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMK- 26709
Query: 225 GDQDSILFIRSAQR------------SDSGRYELTVRVEDLEAKAVID-----ILVIEKP 267
D++SIL+ ++ + S YE V E+ +L I+
Sbjct: 26710 -DRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC 26768
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCT 326
PP ++R+ D+ + +L W P G +++ GY+V++ D G+W T
Sbjct: 26769 EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFI 26828
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
IS L + Y FRVF+ N G + + ++ + I D P + +++E +
Sbjct: 26829 ISGLTQNSQYEFRVFARNAVG--SISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRA 26886
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
G S +L + P P I W K+ E+Q N + + ++ I+
Sbjct: 26887 ---------GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADR 26937
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
+SG Y K N +G AS R+++
Sbjct: 26938 LNSGCYELKLRNAMGSASATIRVQI 26962
Score = 96.3 bits (238), Expect = 5e-20
Identities = 95/412 (23%), Positives = 163/412 (39%), Gaps = 42/412 (10%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D+P P + D+VSS VT SW+PPE G + + YV+E+ + ++ WV ++ +
Sbjct: 21157 DIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRT 21216
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPA-----MLDQPIHIRENIEAPKIRVPRHLRQ 182
T + R L G ++ RV A + G GP + + P + P++
Sbjct: 21217 TYKATR-LTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQV-------- 21267
Query: 183 TYIRQVGETVNLQIPFQGKPKPQATW-----THNGHALDSQRVSMRTGDQDSILFIRSAQ 237
T + + T++ P P + NG + ++ G+ +S+
Sbjct: 21268 TAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGN-----IFKSSG 21322
Query: 238 RSDSGRYELTVRVEDLEAKAVID-----ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+D YE V E++ K+ +L ++ PP L++ L+W P+
Sbjct: 21323 LTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEY 21382
Query: 293 TGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
TG ++ Y+V+K D G+W T+S L +Y FRV ++N G +
Sbjct: 21383 TGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISP 21442
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ + I D PK ++ F + G + +L V P P
Sbjct: 21443 PSEPSDA--ITCRDDVEAPKIKVDVKFKDTVILKA---------GEAFRLEADVSGRPPP 21491
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ W K+ E++G K L + + DSG YT A N G A
Sbjct: 21492 TMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 21543
Score = 94.4 bits (233), Expect = 2e-19
Identities = 96/427 (22%), Positives = 163/427 (38%), Gaps = 50/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ V +D+V++ S+T+SW PP+ G + Y++E + W VS
Sbjct: 22240 KPGPPTGPVK-------MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 22292
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGP-----PAMLDQPIHIRENIEAPKIRV 176
A T + R L G ++ R++A + G P + P + P + +
Sbjct: 22293 ATVARTTIKACR-LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 22351
Query: 177 PRHLRQTYIRQVGETVN------LQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
R + Q E ++ + + K + W Q TG ++ +
Sbjct: 22352 SS--RDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 22409
Query: 231 LFIRSAQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAAL 285
YE V E++ + V + V P PP + V + L
Sbjct: 22410 ------------EYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTL 22457
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSEN 344
QW P G +++ GY+V+K + G+W T ++ L+ + Y FRV + N
Sbjct: 22458 QWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARN 22517
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G+ + + + I D P+ S P + + H G S ++
Sbjct: 22518 AAGVFSEPS--ESTGAITARDEVDPPR------ISMDPKYKDTIVVHA---GESFKVDAD 22566
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ P P I W+K E+ + S +L ++ DSG Y KA NV GE S
Sbjct: 22567 IYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERS 22626
Query: 465 VDCRLEV 471
V ++V
Sbjct: 22627 VTVNVKV 22633
Score = 90.5 bits (223), Expect = 3e-18
Identities = 95/411 (23%), Positives = 162/411 (39%), Gaps = 38/411 (9%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
DVP P + + DV+ +T+SW+PP+ G + Y++E W VS+
Sbjct: 17602 DVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK- 17660
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ + +L G +++ RV A + G GPP LD + ++ +P P T I +
Sbjct: 17661 TKLKIPHLQKGCEYVFRVRAENKIGVGPP--LDSTPTVAKHKFSPP-SPPGKPVVTDITE 17717
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
TV+ +P P + + + V + + F R + YE
Sbjct: 17718 NAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYEFR 17776
Query: 248 VRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
V E+L + + I+ PGPP + +L D A L WT P G + +L
Sbjct: 17777 VFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPIL 17836
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCT--ISDLIIGNSYSFRVFSENLCGLS-----TSA 352
GY+V+ T QW + + C + LI GN Y FR+ + N+ G +
Sbjct: 17837 GYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAES 17896
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
+ K++ H + ++ + I T G + ++ V+ P+P
Sbjct: 17897 VIAKDILHPPEVELDVTCRDVI-----------------TVRVGQTIRILARVKGRPEPD 17939
Query: 413 IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
I W K + + + + L+I++ D G Y A N G A
Sbjct: 17940 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 17990
Score = 87.4 bits (215), Expect = 3e-17
Identities = 96/411 (23%), Positives = 161/411 (39%), Gaps = 48/411 (11%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
+++ +T+ W+ P G + Y++E W + + T L G++
Sbjct: 28063 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNE 28121
Query: 141 FLLRVSAVSSAGAGPPAMLDQPI-HIRENI-EAPKIRVPRHLRQTYIRQV-------GET 191
+ RVSAV+ G G P D + I+ + +AP I P ++ I G +
Sbjct: 28122 YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGS 28181
Query: 192 VNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVE 251
Q + + K W + S+R T + + L ++ YE V E
Sbjct: 28182 EIQQYILERREKKSTRWVK----VISKRPISETRFKVTGL-------TEGNEYEFHVMAE 28230
Query: 252 DLEA---KAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
+ + I L+ + PGPP+ +++ D +L+W+ P G E++GY++
Sbjct: 28231 NAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYII 28290
Query: 304 QKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ 362
+ G W V E T T++DL G Y FRV + N G S VT I+
Sbjct: 28291 EMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIK 28347
Query: 363 KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI 422
D P+ I+ +F + H G S +LF + + P P +W K
Sbjct: 28348 AVDRLTAPELDIDANFKQT---------HVVRAGASIRLFIAYQGRPTPTAVWSKP---- 28394
Query: 423 QGNPKYRA--LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
N RA + TL + + D+G YT N G S+ ++V
Sbjct: 28395 DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 28445
Score = 86.7 bits (213), Expect = 4e-17
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 4/180 (2%)
Query: 180 LRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQR 238
L++ Y VG T+ L + + G+P P TW H L +S+ +++ + + L +++ QR
Sbjct: 30634 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 30693
Query: 239 -SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA-LQWTPPQDTGNT 296
+ +G+Y++ + A++D+ + +KP P+ +++ N+A + W PP D G +
Sbjct: 30694 KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGS 30753
Query: 297 ELLGYMVQKADKKTG-QWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+ Y+V+K + K G +W V TTC I +L Y FRV ++N G+S V+
Sbjct: 30754 WITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVS 30813
Score = 86.3 bits (212), Expect = 6e-17
Identities = 51/201 (25%), Positives = 95/201 (47%), Gaps = 6/201 (2%)
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
APKI+ Q + VG+ + + +P+ PK +A W L ++ + T +Q S
Sbjct: 12999 APKIKTAD---QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSF 13054
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
+ A++ D GRY++ ++ + +A+ I++ VI+ PGP ++ + + + +L W P
Sbjct: 13055 RILE-AKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEP 13113
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGN-SYSFRVFSENLCGLS 349
G ++++GY+V++ D K W +R T++ L G Y FRV + N G
Sbjct: 13114 LTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTG 13173
Query: 350 TSATVTKELAHIQKADIAAKP 370
+ K D+ P
Sbjct: 13174 EPVETDNPVEARSKYDVPGPP 13194
Score = 86.3 bits (212), Expect = 6e-17
Identities = 96/417 (23%), Positives = 171/417 (41%), Gaps = 60/417 (14%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P+ P+ D+V++ ++T+ W PP+ G + Y+LE ++WV ++ T
Sbjct: 20078 IPTGPI--KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTF 20135
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
+ R L G ++ RVSA + G G + +PI R + P P ++ V
Sbjct: 20136 RVTR-LHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVS 20193
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR-YELTV 248
T PK G+ L+ + +++S+L+ R+ + R +++T
Sbjct: 20194 LTWT-------DPKKTGGSPITGYHLEFK-------ERNSLLWKRANKTPIRMRDFKVTG 20239
Query: 249 RVEDLEAK---AVIDILVIEKPG-------------PPSSIRLLDVWGCNAALQWTPPQD 292
E LE + I++ + KP PP ++++ + L WT P+
Sbjct: 20240 LTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKY 20299
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTS 351
G +L GY+V+K D + W P T++DL+ G Y FR+ ++N G ++
Sbjct: 20300 DGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISA 20359
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQL-------FCS 404
+ + E I +D EAP+ + D T G + + S
Sbjct: 20360 PSESTET--------------IICKDEYEAPTI---VLDPTIKDGLTIKAGDTIVLNAIS 20402
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P PK W K +I+ + + S L I+ + D+G YT A N G
Sbjct: 20403 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459
Score = 85.9 bits (211), Expect = 7e-17
Identities = 105/431 (24%), Positives = 166/431 (38%), Gaps = 52/431 (12%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T KP PP V DDVS+ S+T+SW PP G + Y+++ + W
Sbjct: 23319 TLDKPDPPKGPVK-------FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWD 23371
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
VSA T + V L G ++ R+ A + G A+ PI + + P P
Sbjct: 23372 VVSATVARTTLK-VTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPG--PPG 23427
Query: 179 HLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIR---- 234
T I + + P P G+ L+ + +++SIL+ +
Sbjct: 23428 TPFATAISKDSMVIQWHEPVNNGGSPVI-----GYHLERK-------ERNSILWTKVNKT 23475
Query: 235 -------SAQRSDSG-RYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGC 281
AQ + G YE V E++ +A + V P PP + + V
Sbjct: 23476 IIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRN 23535
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRV 340
LQWT P G + + GY+V+K D G+W T T+S L Y FRV
Sbjct: 23536 EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRV 23595
Query: 341 FSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
++N G + + + I AK + + R S P F + + G + +
Sbjct: 23596 IAKNAAGAISKPSDS-------TGPITAKDEVELPR-ISMDPKFRDTIVVNA---GETFR 23644
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L V P P I W++ EI+ + + + L ++ D G Y +A NV
Sbjct: 23645 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 23704
Query: 461 GEASVDCRLEV 471
G S ++V
Sbjct: 23705 GSKSFPVNVKV 23715
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/199 (29%), Positives = 95/199 (47%), Gaps = 11/199 (5%)
Query: 169 IEAP-KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTHNGHALDSQR--VSMR 223
+E P KI +P+ L GE V+++IPF GKP P TW +D+ +
Sbjct: 31019 VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIV 31078
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T S++F +R D+G Y + + + +++ V + P PP +++ DV +
Sbjct: 31079 TRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSV 31138
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L WT P G +++ Y+V+K +W V + T T+ +L SY FRV +E
Sbjct: 31139 NLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAE 31197
Query: 344 NLCGLS-----TSATVTKE 357
N GLS + T+TKE
Sbjct: 31198 NKFGLSKPSEPSEPTITKE 31216
Score = 85.1 bits (209), Expect = 1e-16
Identities = 98/427 (22%), Positives = 161/427 (37%), Gaps = 48/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + D+V+ + +SW+PP G + Y++E G W+PV+
Sbjct: 16911 RPGPPVGPV-------SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 16963
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + V L G ++ R+ A + G P + D + ++ P P
Sbjct: 16964 SASAKTTCK-VSKLLEGKDYIFRIHAENLYGISDPLVSDS-MKAKDRFRVPD--APDQPI 17019
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSILFIRSAQRSD 240
T + + V P G KP + S+R + T D R +
Sbjct: 17020 VTEVTKDSALVTWNKPHDGG-KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLE 17078
Query: 241 SGRYELTVRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+YE V E+ +K V I KP PP + +D + L W PP+
Sbjct: 17079 GCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRH 17138
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT-----ISDLIIGNSYSFRVFSENLCG 347
G +++LGY+V+ +W + P +C ++ L G +Y FRV + N G
Sbjct: 17139 DGGSKILGYIVEYQKVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAG 17196
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCS 404
S A V P+ + +D E P + G + +L
Sbjct: 17197 ESDPAHV---------------PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAI 17241
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
++ P PK+ W K + K R LEIR + D G+Y+ N G +
Sbjct: 17242 IKGVPFPKVTWKKEDRDAP--TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKT 17299
Query: 465 VDCRLEV 471
V ++ V
Sbjct: 17300 VSVKVLV 17306
Score = 84.7 bits (208), Expect = 2e-16
Identities = 101/423 (23%), Positives = 164/423 (38%), Gaps = 52/423 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP L + + V+++WE P G + GYV+E WV + R
Sbjct: 13088 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 13146
Query: 129 QQTVRNLALGD-KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L G ++L RVSA + G G P D P+ R + P P ++ T + +
Sbjct: 13147 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITDVNR 13204
Query: 188 VGETVNLQIP------------FQGKPKPQATW----THNGHALDSQRVSMRTGDQDSIL 231
G ++ + P + + K W T L + + G + S
Sbjct: 13205 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFR 13264
Query: 232 FIRSAQRSDSGRYELT---VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+R+ R G+ V+V D IE+P PP ++ D + L+W
Sbjct: 13265 -VRAQNRIGVGKPSAATPFVKVAD----------PIERPSPPVNLTSSDQTQSSVQLKWE 13313
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSFRVFSENLCG 347
PP G + +LGY++++ ++ W + P T ++ L GN Y +RV +EN G
Sbjct: 13314 PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG 13373
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+S + + L AD A F+E + +F L P T L S
Sbjct: 13374 VSDPSEILGPLT----ADDA-----FVEPTM-DLSAFKDGL--EVIVPNPITILVPST-G 13420
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN----VLGEA 463
P+P W ++ + + + L I D G+YT K N + GE
Sbjct: 13421 YPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEI 13480
Query: 464 SVD 466
V+
Sbjct: 13481 DVN 13483
Score = 83.6 bits (205), Expect = 4e-16
Identities = 97/430 (22%), Positives = 166/430 (38%), Gaps = 69/430 (16%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + V++ T++W+PP + G + Y++E W V
Sbjct: 22636 RPGPPEGPV-------VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVD 22688
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A ++ + V L G+++ R+ AV+ G G P + +P+ + P P+
Sbjct: 22689 ANVQTLSCK-VTKLLEGNEYTFRIMAVNKYGVGEP-LESEPVVAKNPFVVPD--APKAPE 22744
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQR--- 238
T + T + I +P G+ L+ + D++ I + R +R
Sbjct: 22745 VTTV-----TKDSMIVVWERPASDGGSEILGYVLEKR-------DKEGIRWTRCHKRLIG 22792
Query: 239 ---------SDSGRYELTVRVEDLEA----------KAVIDILVIEKPGPPSSIRLLDVW 279
++ YE V E+ + D I KPGPP++ +++D+
Sbjct: 22793 ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDIT 22850
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW--FTVLERYHPTTCTISDLIIGNSYS 337
+ L W+ P G E+ GY+V+K D G+W T + T + L+ + Y+
Sbjct: 22851 RSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYN 22910
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADH---TST 394
FR+ + N G+ A V P I + EAP L
Sbjct: 22911 FRICAINKAGVGEHADV---------------PGPIIVEEKLEAPDIDLDLELRKIINIR 22955
Query: 395 PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
G S +LF ++ P P++ W K EI+ S +L + + +DSG YT
Sbjct: 22956 AGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTL 23013
Query: 455 KAINVLGEAS 464
N G S
Sbjct: 23014 TLENSSGTKS 23023
Score = 82.8 bits (203), Expect = 6e-16
Identities = 88/406 (21%), Positives = 157/406 (38%), Gaps = 29/406 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + +VS+ T++W PP G ++ Y+LE W VS +
Sbjct: 20471 DVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSC 20529
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ L G++++ RVSAV+ G G P +P+ + + P P + + +
Sbjct: 20530 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPG--PPEKPEVSNVTKN 20586
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
TV+ + P + S R S L + + YE V
Sbjct: 20587 TATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRV 20646
Query: 249 RVEDLE-----AKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+ ++A +L+ + PGPPS+ + D +A+L W P G E+ G
Sbjct: 20647 SAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITG 20706
Query: 301 YMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKEL 358
Y+V+ W T T + DL Y+FR+ + N G+ A +
Sbjct: 20707 YVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-- 20764
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
I + ++A DF + L G S ++F ++ P P++ W K+
Sbjct: 20765 VEIVEREMAP--------DFELDAELRRTLVVRA---GLSIRIFVPIKGRPAPEVTWTKD 20813
Query: 419 KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ ++ + + L I + + +D+G + N G+ S
Sbjct: 20814 NINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 20857
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/411 (21%), Positives = 155/411 (37%), Gaps = 40/411 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ + S +SWEPP G + Y+++ W VSA + +T
Sbjct: 19387 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSAT-VPIT 19445
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+V L G ++ R+ A + G G P + +P + + P P + I +
Sbjct: 19446 SCSVEKLIEGHEYQFRICAENKYGVGDP-VFTEPAIAKNPYDPPGRCDPPVISN--ITKD 19502
Query: 189 GETVNLQIPFQGKPKP------------QATWTHNGHALDSQRVSMRTGDQDSILF---I 233
TV+ + P P WT +R TG Q+ + +
Sbjct: 19503 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 19562
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
+ ++ G+ +KA PGPP+ ++ D + +L W P
Sbjct: 19563 TAINKAGPGK-------PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYD 19615
Query: 294 GNTELLGYMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
G + ++GY+V+ + W + + T ++ L+ Y FRV++ N G S
Sbjct: 19616 GGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 19675
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ V + H K DI P+G ++ D + G + +L+ V+ P P
Sbjct: 19676 SDVPDK--HYPK-DILIPPEGELDADLRKTLILRA---------GVTMRLYVPVKGRPPP 19723
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
KI W K + ++ S L + +D+G Y N G+
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 19774
Score = 81.6 bits (200), Expect = 1e-15
Identities = 99/427 (23%), Positives = 165/427 (38%), Gaps = 49/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP V D+VS+ V +SWEPP G + Y++E + W VS
Sbjct: 24404 KPGPPVGPV-------RFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS 24456
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A T + + L G ++ R+ A + G P LD I ++ P + P
Sbjct: 24457 ATVARTTIK-ITKLKTGTEYQFRIFAENRYGKSAP--LDSKAVI---VQYP-FKEPGPPG 24509
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM------RTGDQDSILFIRS 235
++ + + L + + T H ++ S+ +T QD+ ++
Sbjct: 24510 TPFVTSISKDQML-VQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF--KT 24566
Query: 236 AQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAALQWTPP 290
+ YE V E++ + V + V P PP + + N L+W P
Sbjct: 24567 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 24626
Query: 291 QDTGNTELLGYMVQKADKKTGQWF-----TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
G +++ GY+V+K D G+W VLE T T+S L+ Y FRV + N
Sbjct: 24627 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLE----TEFTVSGLVEDQRYEFRVIARNA 24682
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
G + + + I D P ++ P + + H G + L +
Sbjct: 24683 AGNFSEPSDSS--GAITARDEIDAPNASLD------PKYKDVIVVHA---GETFVLEADI 24731
Query: 406 RASPKPKIIWMKNKMEIQGN-PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
R P P ++W K+ E++ + S TL ++ D G Y K NV G S
Sbjct: 24732 RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 24791
Query: 465 VDCRLEV 471
+ ++V
Sbjct: 24792 IPITVKV 24798
Score = 81.6 bits (200), Expect = 1e-15
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 17/229 (7%)
Query: 251 EDLEAKAVIDILV-IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ LE +V+ I EKPG P + V + + W PP G ++ Y ++K +KK
Sbjct: 30808 DPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKK 30867
Query: 310 TGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAA 368
+W +V E T ++ +LI G Y FRV ENL G S + +++ + K+D+
Sbjct: 30868 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT--PKSDVPI 30925
Query: 369 KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNP-K 427
+AP F + L + + L C V PKP + W + EI + K
Sbjct: 30926 -----------QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 30974
Query: 428 YRALS-EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
YR + G L I + D+ VY +A N G S LEV+ A
Sbjct: 30975 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPA 31023
Score = 80.1 bits (196), Expect = 4e-15
Identities = 103/486 (21%), Positives = 178/486 (36%), Gaps = 60/486 (12%)
Query: 4 KNTSEGPACSPEETASESAKVPTAEPPG--EVAVSESTREEQVPKPQAPAPQAPTASTAT 61
K T+ S + S S K + E G E+ VS S VP T
Sbjct: 25436 KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPI---------TIIVLD 25486
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP + +D+VS S+T+SW PPE G + Y++E ++ W VS
Sbjct: 25487 RPGPPGP--------IRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS 25538
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAV-----SSAGAGPPAMLDQPIHIRENIEAPKIRV 176
+ + VR L G ++ RV A SS + + P PK+
Sbjct: 25539 QAVARTSIKIVR-LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV-- 25595
Query: 177 PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSA 236
+ + V Q+P G+ L+ + S + + + I
Sbjct: 25596 ------VHATKSTMLVTWQVPVNDGGSRVI-----GYHLEYKERSSILWSKANKILIADT 25644
Query: 237 QRSDSG-----RYELTVRVEDLE-----AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
Q SG YE V E++ +K+ + + PP + ++ + +L+
Sbjct: 25645 QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLK 25704
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENL 345
W+ P G ++ GY+V++ + G+W T +++L Y FRVF+ N
Sbjct: 25705 WSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNA 25764
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
+ + ++ I D P+ ++ F + G ++ +
Sbjct: 25765 A--DSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI---------VVKAGEVLKINADI 25813
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
P P I W K+ +EI+ + +S L ++ D+G Y NV G SV
Sbjct: 25814 AGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSV 25873
Query: 466 DCRLEV 471
+V
Sbjct: 25874 AVNCKV 25879
Score = 79.7 bits (195), Expect = 5e-15
Identities = 57/211 (27%), Positives = 89/211 (42%), Gaps = 16/211 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + E+P PP I L+DV + +L W P+ G + +LGY+V+ K + +
Sbjct: 22035 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 22094
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T T TI+ LI G YSFRV ++N G+S ++ +
Sbjct: 22095 WAT-CATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV-------------- 22139
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
I +D P+F T G ++ P P + W K+ + ++ + A S
Sbjct: 22140 -IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 22198
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ L I+ D G Y K N GEA
Sbjct: 22199 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229
Score = 79.0 bits (193), Expect = 9e-15
Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 12/205 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P PP +++ D + L W PP++ G + + GY+V++ + + +W E T
Sbjct: 13588 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 13647
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
++ L G Y++RV + N G S + T+E IQ D P+ F++ +
Sbjct: 13648 VTGLEEGKWYAYRVKALNRQGASKPSRPTEE---IQAVDTQEAPEIFLD---------VK 13695
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
LA T G +L +V P+PKI W K M ++ + + + T+ I
Sbjct: 13696 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 13755
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
D+G Y +A+NV G A+ + V
Sbjct: 13756 SDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 78.6 bits (192), Expect = 1e-14
Identities = 87/447 (19%), Positives = 169/447 (37%), Gaps = 72/447 (16%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
++P+ PS+ V PS P L + +++ ++ + W PE+ G + Y++E
Sbjct: 14066 SEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDV 14125
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
W V + T+ TV L G ++ RV+A ++ G ++ + ++ P
Sbjct: 14126 RRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP 14184
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
Y V + + + +P N QR + ++ +
Sbjct: 14185 G--------PPYALAVVDVTKRHVDLKWEPPK------NDGGRPIQRYVIEKKERLGTRW 14230
Query: 233 IRSAQRSDSG-RYELTVRVEDLEAKAVI---------------DILVIEKP----GPPSS 272
+++ + + + +T +E E + + +IL IE P PP
Sbjct: 14231 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLD 14290
Query: 273 IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDL-- 330
+ + D + A+ W PP+ G + ++GY V+ T +W V R I DL
Sbjct: 14291 LHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSR------PIKDLKF 14344
Query: 331 ------IIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ Y RV + N G+S + +++ + + +D P+
Sbjct: 14345 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 14389
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
D G + RA P P + W K+ E++ + + ++ LE+ K
Sbjct: 14390 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 14449
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
D+G+YT N LG A+ ++V
Sbjct: 14450 VRADAGIYTITLENKLGSATASINVKV 14476
Score = 77.0 bits (188), Expect = 3e-14
Identities = 92/421 (21%), Positives = 155/421 (36%), Gaps = 53/421 (12%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP + V++ +T+ W PP G + Y++E W VS
Sbjct: 26965 KPGPPGGPIE-------FKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS 27017
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + G++++ RV AV+ G G P D + + +P
Sbjct: 27018 EH-LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPE--- 27073
Query: 182 QTYIRQVGETVNLQIPF------------QGKPKPQATWTH--NGHALDS-QRVSMRTGD 226
T I + TV P + + K W D+ Q+V+ T +
Sbjct: 27074 VTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTEN 27133
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
D + + + G + E E D I+ PGPP+ IR+ D + L
Sbjct: 27134 SDYQYRVCAVNAAGQGPFS-----EPSEFYKAAD--PIDPPGPPAKIRIADSTKSSITLG 27186
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSEN 344
W+ P G + + GY+V+ + +W TV + T +S+L G +Y FRV + N
Sbjct: 27187 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVN 27246
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTST---PGYSTQL 401
G + + + +D EAP +A TS G Q+
Sbjct: 27247 CAGQGEPIEMNEPVQ---------------AKDILEAPEIDLDVALRTSVIAKAGEDVQV 27291
Query: 402 FCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P P + W K++ + + +Y + L I + + D+G Y N +G
Sbjct: 27292 LIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 27351
Query: 462 E 462
E
Sbjct: 27352 E 27352
Score = 75.9 bits (185), Expect = 8e-14
Identities = 60/238 (25%), Positives = 98/238 (41%), Gaps = 24/238 (10%)
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
+ +I + R ++ G + V VE ++A + E P PP + L DV +A+L
Sbjct: 24181 EGAIYYFRVMAENEFG---VGVPVETVDA-----VKAAEPPSPPGKVTLTDVSQTSASLM 24232
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W P+ G + +LGY+V+ K T +W V E ++ L G Y FRV + N
Sbjct: 24233 WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQEYQFRVKAYNEK 24291
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
G K+D I +D + PS P ++ G ++ V
Sbjct: 24292 G---------------KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVI 24336
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P+P I W+K+ ++ + L I++ + D G YT A N G A+
Sbjct: 24337 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 24394
Score = 74.7 bits (182), Expect = 2e-13
Identities = 95/428 (22%), Positives = 168/428 (39%), Gaps = 54/428 (12%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PPS+ P P+ D++ + SV +SW+ PE G + Y +E + W V +
Sbjct: 27656 PPSK--PKGPI--RFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 27711
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTY 184
T + V NL ++ RV A + G + QP+ + + R+P
Sbjct: 27712 ARTTFK-VPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPG------ 27758
Query: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR- 243
G+ V + G ++G + + + +++SIL+ + SGR
Sbjct: 27759 --PPGKPVIYNVTSDGMSLTWDAPVYDGGS-EVTGFHVEKKERNSILWQKVNTSPISGRE 27815
Query: 244 YELTVRVEDLE-------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
Y T VE L+ +K + + ++ PG P I DV
Sbjct: 27816 YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETIT 27872
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L+W PP G ++++GY ++K T++ L G+ Y FR+ + N
Sbjct: 27873 LKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARN 27932
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G T + ++ I D P +E P + L + G S ++
Sbjct: 27933 AVG--TISPPSQSSGIIMTRDENVPP--IVEF----GPEYFDGLIIKS---GESLRIKAL 27981
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V+ P P++ W K+ +EI+ G +L +R + GVYT +A N G A
Sbjct: 27982 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 28041
Query: 465 VDCRLEVK 472
+ +++V+
Sbjct: 28042 AEIKVKVQ 28049
Score = 73.6 bits (179), Expect = 4e-13
Identities = 79/294 (26%), Positives = 118/294 (40%), Gaps = 28/294 (9%)
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
VGET L+ G P+ W +G L SQ+ ++ S L I S +R D+G Y
Sbjct: 5717 VGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF 5776
Query: 247 TVR--VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
V+ V AV+D V ++ PPS R L ++TG +LG
Sbjct: 5777 QVQNNVGKSSCTAVVD--VSDRAVPPSFTRRL--------------KNTGG--VLGASCI 5818
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ-- 362
K G + +H T +S G Y FS+N+C L ++ + ++ +
Sbjct: 5819 LECKVAGSSPISVAWFHEKTKIVS----GAKYQ-TTFSDNVCTLQLNSLDSSDMGNYTCV 5873
Query: 363 KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI 422
A++A + E PSF + PG + +R +P K+ W + E+
Sbjct: 5874 AANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGAREL 5933
Query: 423 QGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ E V LE+ SG YTC N G+AS RL VK AA
Sbjct: 5934 VKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAA 5987
Score = 72.8 bits (177), Expect = 6e-13
Identities = 91/421 (21%), Positives = 155/421 (36%), Gaps = 39/421 (9%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ L ++ +++ ++SW P+ G + Y++E W +
Sbjct: 25882 KPGPPAGP-------LEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-IC 25933
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ +T V L G++++ RV+ V+ G G P + I + P P L
Sbjct: 25934 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP-LESVAIKALDPFTVPS--PPTSLE 25990
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDS 241
T + + T+ P + + +S R L ++S +
Sbjct: 25991 ITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREG 26050
Query: 242 GRYELTVRVED---LEAKAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
YE V E+ L + L+ + P PPS +++D + W P
Sbjct: 26051 CEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFD 26110
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
G + GY V+ W T ++ T TIS L G Y FRV S N G S +
Sbjct: 26111 GGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSD 26170
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCSVRASPK 410
++ P+ I ++ E P F ++ G S + R P
Sbjct: 26171 -------------SSDPQ--IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 26215
Query: 411 PKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
P ++W K +++ + T+E + DSG YT NVL AS+ ++
Sbjct: 26216 PNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRN--DSGKYTLTIQNVLSAASLTLVVK 26273
Query: 471 V 471
V
Sbjct: 26274 V 26274
Score = 72.4 bits (176), Expect = 8e-13
Identities = 49/217 (22%), Positives = 89/217 (41%), Gaps = 16/217 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ I V E P PP I + DV + +L WT P+ G ++++ Y+V+ K + +
Sbjct: 23117 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEK 23176
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W + R I++L G Y FRV + N G S ++ +
Sbjct: 23177 W-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI-------------- 23221
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+ +D P + ++ G ++ + PKP I W K+ + ++ +
Sbjct: 23222 -VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTD 23280
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRL 469
+ TL I++ D G Y NV+G+ + +
Sbjct: 23281 SLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 23317
Score = 71.2 bits (173), Expect = 2e-12
Identities = 75/305 (24%), Positives = 124/305 (40%), Gaps = 28/305 (9%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNG-HALDSQRVSMRTGDQ 227
I+AP V R Y + G+ + L+ F G P TW NG + SQR ++ T ++
Sbjct: 7864 IKAPAKFVKR--LNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK 7921
Query: 228 DSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW-GCNAALQ 286
+IL I S+ D+G+Y + + IL++E P + + V G +A+LQ
Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQ 7981
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTI--SDLIIGNSYSFRVFSEN 344
T +G K D K T + T+ + + I +S + +EN
Sbjct: 7982 C----QLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAEN 8037
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G +++T +Q+ + PSF++ L D T G C+
Sbjct: 8038 SVGEVSASTFLT----VQEQKLP--------------PSFSRQLRDVQETVGLPVVFDCA 8079
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ S + W K+ ++ +P + TL I K +G Y+C A N +G AS
Sbjct: 8080 ISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSAS 8139
Query: 465 VDCRL 469
RL
Sbjct: 8140 SSARL 8144
Score = 71.2 bits (173), Expect = 2e-12
Identities = 68/289 (23%), Positives = 112/289 (38%), Gaps = 12/289 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + DV++ S ++W PP G + YV+E + W +S+ + T
Sbjct: 13782 DKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSS-TVKDT 13840
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
L +++ RV+A + G G P PI + + P P L + I +
Sbjct: 13841 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA-SPITAKYQFDPP--GPPTRLEPSDITKD 13897
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
T+ P P + D+ + R ++ +Y V
Sbjct: 13898 AVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRV 13957
Query: 249 RVEDL-----EAKAVIDILV---IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+L +K+ IL+ I+ P PP + DV + L WT P+ G ++
Sbjct: 13958 LAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIES 14017
Query: 301 YMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+++ T +W V E T + L+ G YSFRV + N G S
Sbjct: 14018 YVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 14066
Score = 69.3 bits (168), Expect = 7e-12
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 20/215 (9%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + V E P PP + L+DV A ++W P+ G +++ GY+V+ K + +
Sbjct: 25282 LPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEK 25341
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T + TIS L G Y FRV + N G ++D
Sbjct: 25342 WSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKG---------------RSDPRQLGVP 25385
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV--RASPKPKIIWMKNKMEIQGNPKYRA 430
I RD PS P HT QL V + P+ + W K+ ++ +
Sbjct: 25386 VIARDIEIKPSVELPF--HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNV 25443
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
S + V +L I++ S D G Y N G +V
Sbjct: 25444 SSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 25478
Score = 68.2 bits (165), Expect = 2e-11
Identities = 97/427 (22%), Positives = 157/427 (36%), Gaps = 57/427 (13%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSARPMM 126
D P P+ +D+ +SV WEPP G + Y LE + SEW+ V++ +
Sbjct: 14800 DTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTS-TLR 14858
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR 186
+ +V L G ++L RV A + G GPP + +P+ ++ P + +
Sbjct: 14859 HCKYSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAP-----DKPIVE 14912
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG---- 242
V T N + +PK + G+ L+ + V+ + + + + + + G
Sbjct: 14913 DV--TSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 14969
Query: 243 -RYELTVRVEDL----------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
Y V E+ + K D I PGPP R+ D L+W PP
Sbjct: 14970 LTYVFRVCAENAAGPGKFSPPSDPKTAHD--PISPPGPPIP-RVTDTSSTTIELEWEPPA 15026
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGL-- 348
G E++GY V K T +W E+ T+ ++ G Y RV + N G
Sbjct: 15027 FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGP 15086
Query: 349 --STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
T E ++ KG I+ G + ++ V
Sbjct: 15087 PGETQPVTVAEPQEPPAVELDVSVKGGIQ-----------------IMAGKTLRIPAVVT 15129
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQ--GVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P +W K + E+ K R + + L I+ D G Y A N G
Sbjct: 15130 GRPVPTKVWTKEEGELD---KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 15186
Query: 465 VDCRLEV 471
R+EV
Sbjct: 15187 AAARVEV 15193
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/235 (22%), Positives = 94/235 (40%), Gaps = 30/235 (12%)
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
F R ++ G E T E ++A E P PP S+ ++D+ +L W P+
Sbjct: 20938 FFRVMAENEYGIGEPTETTEPVKAS--------EAPSPPDSLNIMDITKSTVSLAWPKPK 20989
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS-- 349
G +++ GY+++ K + QW T + C + +L G Y+F+V + N G S
Sbjct: 20990 HDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 21048
Query: 350 --TSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+ + KE + + D+ + + + G + ++ V
Sbjct: 21049 RESRPVIVKEQTMLPELDLRGIYQKLV-----------------IAKAGDNIKVEIPVLG 21091
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
PKP + W K ++ + + L I + DSG Y A N++GE
Sbjct: 21092 RPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 21146
Score = 66.6 bits (161), Expect = 5e-11
Identities = 85/431 (19%), Positives = 158/431 (36%), Gaps = 63/431 (14%)
Query: 69 DVPSAPLL-LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D P P + D+ + + ++SW P G + Y++E C +WV A +
Sbjct: 18990 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTK 19048
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T V L G +++ RV A + G + +P+ + + VP + + +
Sbjct: 19049 TSCRVGKLIPGQEYIFRVRAENRFG------ISEPLTSPKMVAQFPFGVPSEPKNARVTK 19102
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRS-DSGRYEL 246
V N F +P + G + + + +++S+L++++ S Y
Sbjct: 19103 V----NKDCIFVAWDRPDSD---GGSPIIGYLIERK--ERNSLLWVKANDTLVRSTEYPC 19153
Query: 247 TVRVEDLEAKAVIDILVIEKPG------------------PPSSIRLLDVWGCNAALQWT 288
VE LE I + K G PP ++DV +L W
Sbjct: 19154 AGLVEGLEYS--FRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWA 19211
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
P+ G ++++GY V+ +W T + T + L Y FR +
Sbjct: 19212 RPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTA 19271
Query: 346 CGLSTSATVTKELAHIQ-----KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
+S + + + + + D++ K + T G +
Sbjct: 19272 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL-----------------TVKAGTNVC 19314
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L +V P P + W K+ ++ + ++ +CTLE+ + DSG YT A N
Sbjct: 19315 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 19374
Query: 461 GEASVDCRLEV 471
G S +L+V
Sbjct: 19375 GSKSATIKLKV 19385
Score = 66.2 bits (160), Expect = 6e-11
Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 31/222 (13%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-----KADKKTGQWFTVLE 318
I P PP +++ + L W PP++ G + + Y+V+ K W +
Sbjct: 16009 IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK 16068
Query: 319 R-YHPTTCTISDLIIGNSYSFRVFSENLCGLST-SATVTKELAHIQKADIAAKPKGFIER 376
R T+ DL+ G Y FRV + N G+S SATV Q+ D+ P +
Sbjct: 16069 RDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGP--CDCQRPDM---PPSIDLK 16123
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK-------NKMEIQGNPKYR 429
+F E G + + ++ P P + W K NK + +
Sbjct: 16124 EFMEVEE------------GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN 16171
Query: 430 ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L CTL I + D+G+YT A+N LG AS + RL V
Sbjct: 16172 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213
Score = 66.2 bits (160), Expect = 6e-11
Identities = 91/429 (21%), Positives = 169/429 (39%), Gaps = 73/429 (17%)
Query: 77 LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLA 136
+ + VS+ S +SW P+ G + Y++E G + W V++ + TQ V +L
Sbjct: 28748 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLT 28806
Query: 137 LGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQI 196
++ RVS+ + G P L+ I E+ P P ++ ++ +
Sbjct: 28807 KYMEYSFRVSSENRFGVSKP--LESAPIIAEHPFVPP-SAPTRPEVYHVSANAMSIRWEE 28863
Query: 197 PFQ-GKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSD-SGRYELTVRVEDLE 254
P+ G K W ++++IL+++ + Y++T VE LE
Sbjct: 28864 PYHDGGSKIIGYWVEKK-------------ERNTILWVKENKVPCLECNYKVTGLVEGLE 28910
Query: 255 -------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
++ ++ ++ PG P + DV +L W+ P G
Sbjct: 28911 YQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VTDVTRSTVSLIWSAPAYDGG 28967
Query: 296 TELLGYMVQK---ADKKTGQW----FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++++GY++++ ++ G+W +T++ T +S+ G++Y FRV ++N G+
Sbjct: 28968 SKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE---GDTYEFRVLAKNAAGV 29024
Query: 349 ------STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
ST ++ KA++ A+ G + T G L
Sbjct: 29025 ISKGSESTGPVTCRDEYAPPKAELDARLHGDLV----------------TIRAGSDLVLD 29068
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
+V P+PKIIW K E+ K T I+ DSG YT N G
Sbjct: 29069 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 29128
Query: 463 ASVDCRLEV 471
+V ++V
Sbjct: 29129 KAVSVMVKV 29137
Score = 65.1 bits (157), Expect = 1e-10
Identities = 81/308 (26%), Positives = 119/308 (38%), Gaps = 51/308 (16%)
Query: 183 TYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDS 241
+Y+ GE+ L +G P Q TW N L +S V M + ++IL I + DS
Sbjct: 3746 SYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDS 3805
Query: 242 GRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLD----VWGCNAALQWTPPQDTGNTE 297
G Y V D+ + + +VI++P PS I+ L+ V G NA LQ TG E
Sbjct: 3806 GSYSCEA-VNDVGSDSCSTEIVIKEP--PSFIKTLEPADIVRGTNALLQ-CEVSGTGPFE 3861
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
+ + DKK I +S +R+FS+ + V E
Sbjct: 3862 ISWFK----DKKQ---------------------IRSSKKYRLFSQK-------SLVCLE 3889
Query: 358 LAHIQKADIA----------AKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+ AD+ K E P+F + + D + G + L +VR
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRG 3949
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDC 467
S + WMK + I+ + K + GV L I G YTC A N G +
Sbjct: 3950 SEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVG 4009
Query: 468 RLEVKASA 475
L VK A
Sbjct: 4010 ELIVKEPA 4017
Score = 65.1 bits (157), Expect = 1e-10
Identities = 73/290 (25%), Positives = 109/290 (37%), Gaps = 24/290 (8%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG-DQDSILFIRSAQRSDSGRYELT 247
G L+ G P+ A W +G L + T ++ + L I A+ SD G Y
Sbjct: 6659 GNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFE 6718
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
V+ ++ + + V ++ PPS IR L NA L G + +L V +
Sbjct: 6719 VKNSVGKSNCTVSVHVSDRIVPPSFIRKLK--DVNAIL--------GASVVLECRVSGSA 6768
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE--LAHIQKAD 365
+ WF + I+ FSEN+C L+ S + + A+
Sbjct: 6769 PISVGWFQD-----------GNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAAN 6817
Query: 366 IAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN 425
+A + E PSF Q PG S +R +P K+ W K E+
Sbjct: 6818 VAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPG 6877
Query: 426 PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
E V LE+ + P +SG Y+C N G AS L VK A
Sbjct: 6878 ESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA 6927
Score = 65.1 bits (157), Expect = 1e-10
Identities = 92/432 (21%), Positives = 162/432 (37%), Gaps = 47/432 (10%)
Query: 56 TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
T +P PP PL +T V++ ++W PP + G + Y++E
Sbjct: 24795 TVKVLDRPGPPE-----GPLKVT--GVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL 24847
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP--- 172
W VS + + V L G++++ RV AV+ G G P + P+ + P
Sbjct: 24848 SWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEP-LESGPVTACNPYKPPGPP 24905
Query: 173 -----KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRT 224
+ T+ R V G T + + K WT N L R+ +
Sbjct: 24906 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 24965
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
+ R A + +G E + E D L PGPPS+ ++ D + +
Sbjct: 24966 LTEGHSYEFRVAAENAAGVGEPS---EPSVFYRACDALY--PPGPPSNPKVTDTSRSSVS 25020
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-----TISDLIIGNSYSFR 339
L W+ P G + GY+V+ + +W T PT T++ L Y+FR
Sbjct: 25021 LAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP---PTGLQGKQFTVTKLKENTEYNFR 25077
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
+ + N G+ AT+ + ++ + P+ ++ D + +
Sbjct: 25078 ICAINSEGVGEPATLPGSVVAQERIE---PPEIELDADLRKVVVLRASA---------TL 25125
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
+LF +++ P+P++ W K + + + S L I + FDSG Y N
Sbjct: 25126 RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTLENN 25183
Query: 460 LGEASVDCRLEV 471
G + + V
Sbjct: 25184 SGSKTAFVNVRV 25195
Score = 63.9 bits (154), Expect = 3e-10
Identities = 66/275 (24%), Positives = 113/275 (41%), Gaps = 22/275 (8%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+TV LQ +G TW + + ++ M + ++L I Q S G+Y
Sbjct: 3938 GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCL 3997
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW-GCNAALQWTPPQDTGNTELLGYMVQKA 306
E +V +++V E L+ V G A L++T G EL +
Sbjct: 3998 AENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTV---AGTPEL-----KPK 4049
Query: 307 DKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADI 366
K G+ ++Y + N + +S L S T E+++ +
Sbjct: 4050 WYKDGRPLVASKKYRIS-------FKNNVAQLKFYSAEL---HDSGQYTFEISNEVGSSS 4099
Query: 367 AAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNP 426
++RD AP FT+PL + S + +L C + S ++ W K+ EI +
Sbjct: 4100 CETTFTVLDRDI--APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASD 4157
Query: 427 KYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+YR +G +LEI + D+G +TC+A N +G
Sbjct: 4158 RYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVG 4192
Score = 63.2 bits (152), Expect = 5e-10
Identities = 65/290 (22%), Positives = 114/290 (39%), Gaps = 16/290 (5%)
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRSDSGRYEL 246
VGE+ + + G + +W + + S + + + + L + + DSG+Y
Sbjct: 8166 VGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTC 8225
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
E + + + E+ PPS + L T + GN+ L V +
Sbjct: 8226 YAVNEVGKDSCTAQLNIKERLIPPSFTKRLSE---------TVEETEGNSFKLEGRVAGS 8276
Query: 307 DKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADI 366
T W+ PT S+ I + V G++ + T ++++ A
Sbjct: 8277 QPITVAWYKNNIEIQPT----SNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSN--DAGS 8330
Query: 367 AAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNP 426
A + ++ + P F Q L T + G QL C V+ S +I W+K EI+ +
Sbjct: 8331 ALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSD 8390
Query: 427 KYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ G LE+R + DSG Y CKA NV G + ++ +K A
Sbjct: 8391 RCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPA 8440
Score = 63.2 bits (152), Expect = 5e-10
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Query: 59 TATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASE 116
T +KP A D P P + VS +TV W PPE G + GY LE + ++
Sbjct: 18382 TESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 18441
Query: 117 WVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WVPV+ + + V+NL ++ RV A + G G P++ +P+ ++ IE P
Sbjct: 18442 WVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP 18497
Score = 63.2 bits (152), Expect = 5e-10
Identities = 53/201 (26%), Positives = 82/201 (40%), Gaps = 5/201 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P L + +S SVT+ WE PE G + GY +E + G S W + +
Sbjct: 30429 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 30488
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR-ENIEAPKIRVPRHLRQTYIRQ 187
Q T+ L ++ RV A + G P I + + EAP IR + +
Sbjct: 30489 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTK 30545
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
+GE L G+P P W G L S++ M + + L + + ++ D G Y
Sbjct: 30546 LGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 30605
Query: 247 TVRVEDLEAKAVIDILVIEKP 267
E E + +L+ P
Sbjct: 30606 IATNEVGEVETSSKLLLQATP 30626
Score = 62.0 bits (149), Expect = 1e-09
Identities = 63/300 (21%), Positives = 121/300 (40%), Gaps = 38/300 (12%)
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQD 228
E PK + L + + + GE++ L+ G P+ + +W N L +S + +M +
Sbjct: 6362 EPPKF--VKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSV 6419
Query: 229 SILFIRSAQRSDSGRY--ELTVRVEDLEAKAVIDI----LVIEKPGPPSSIRLLDVWGCN 282
++L I A DSG Y E V D + + + +KP P +++ DV
Sbjct: 6420 ALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVI-LQ 6478
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
+ TPP + + ++ + + + F + ++ T+ I +L + + +
Sbjct: 6479 CEISGTPPFE------VVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKA 6532
Query: 343 ENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
N G T + K F E P F + L+D ++ G + +L
Sbjct: 6533 TNEVGSDTCSCSVK---------------------FKEPPRFVKKLSDTSTLIGDAVELR 6571
Query: 403 CSVRASPKPKIIWMKNKME-IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
V ++W+K++ E I+ + R + TL++ P +SG Y C+ N G
Sbjct: 6572 AIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAG 6631
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 25/211 (11%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+LV E P P+ + ++DV L W P G + L GY+++ T +W V+
Sbjct: 29629 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT-L 29687
Query: 321 HPTTC--TISDLIIGNSYSFRVFSENLCGLS-----TSATVTKELAHIQKADIAAKPKGF 373
PT T++ L G Y FR+ ++N G+S +A ++L + D++ P+
Sbjct: 29688 KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKT 29747
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I P+ G +L + P P W +++ + + +
Sbjct: 29748 IH-----VPA------------GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 29790
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V L IR+ + D+G YT + NV G S
Sbjct: 29791 TKVAKLTIRETTIRDTGEYTLELKNVTGTTS 29821
Score = 61.6 bits (148), Expect = 1e-09
Identities = 33/103 (32%), Positives = 55/103 (53%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + DVS +T++W PPE G + GY++E A WV V+ P+ +T+
Sbjct: 29931 IPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 29990
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
L G ++ RV+A+++ G+G P+ +PI + I P
Sbjct: 29991 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPP 30033
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/104 (32%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV-SARPMMVT 128
VP AP + +++ +S+T++W PE G +Q Y+LE + ++ WV V S RP+ T
Sbjct: 28151 VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISET 28210
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ V L G+++ V A ++AG GP + + + I RE + P
Sbjct: 28211 RFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 28254
Score = 60.8 bits (146), Expect = 3e-09
Identities = 36/95 (37%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 380 EAPSFTQPL-ADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCT 438
E P F + L A + G S QL C + SP+ K+ W +N E+ + KY V
Sbjct: 6362 EPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL 6421
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
L I + S DSG Y C+A N +G+AS L VKA
Sbjct: 6422 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKA 6456
Score = 60.5 bits (145), Expect = 3e-09
Identities = 68/297 (22%), Positives = 123/297 (41%), Gaps = 44/297 (14%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+++ L+ + G TW +G + S++ ++ T ++ IL I ++ + D+G+Y +
Sbjct: 6000 GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQY--S 6057
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
+E+ + V LV PP + L+ AA+ G++ L V
Sbjct: 6058 CEIENEAGRDVCGALVSTLE-PPYFVTELEP--LEAAV--------GDSVSLQCQVAGTP 6106
Query: 308 KKTGQWFTVLERYHPT------------TCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+ T W+ + PT T + + I +S + +EN G ++S TV
Sbjct: 6107 EITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 6166
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ IQ+ + PSF + L D T G L C + S ++ W
Sbjct: 6167 R----IQERQLP--------------PSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCW 6208
Query: 416 MKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
++ + ++ + + V TL+I + SG Y+C A N LG AS RL +
Sbjct: 6209 YRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 6265
Score = 59.3 bits (142), Expect = 7e-09
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Query: 364 ADIAAKPKGFIERDFSEAPSFTQPLA-DHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI 422
++IA K + E P F + L T+ C + SP+ K++W K++ EI
Sbjct: 7287 SNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEI 7346
Query: 423 QGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
Q + K+R V LE+ S DSG YTC+A N G AS L+VK
Sbjct: 7347 QESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 58.5 bits (140), Expect = 1e-08
Identities = 62/272 (22%), Positives = 104/272 (38%), Gaps = 34/272 (12%)
Query: 208 WTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKP 267
WT + + Q +++ Q F R A + G VE EA + + + + P
Sbjct: 16663 WTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPF---VETSEALVIREPITV--P 16717
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT--- 324
P + + +V L W PP+ G +E++ Y+++ T E++H T
Sbjct: 16718 ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT-------EKFHKVTNDN 16770
Query: 325 -----CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFS 379
T+ L G++Y +RV + N+ G + TK I D A P + DF
Sbjct: 16771 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAPPT--LHLDFR 16825
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
+ T G + L PKPK+ W K++ ++ + + + L
Sbjct: 16826 DKL---------TIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLAL 16876
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
E K DSG Y N G C++ V
Sbjct: 16877 EKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 16908
Score = 58.5 bits (140), Expect = 1e-08
Identities = 64/267 (23%), Positives = 100/267 (37%), Gaps = 32/267 (11%)
Query: 207 TWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
TW+ H S + + + F R ++ G E E ++A V
Sbjct: 27411 TWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV-------- 27462
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P P + + D + L WT P G + + Y+V++ K W TC
Sbjct: 27463 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWS---HAGISKTCE 27519
Query: 327 I--SDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
I S L + FRVF++N GLS T+ I ++ P E D S+ P
Sbjct: 27520 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----GPITVKELIITP----EVDLSDIPG- 27570
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
A T G++ L + PKP I W+K+ + ++ + R + TL I+
Sbjct: 27571 ----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 27626
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
G YT N + CR+ V
Sbjct: 27627 KKEHGGKYTVILDNAV------CRIAV 27647
Score = 57.8 bits (138), Expect = 2e-08
Identities = 70/296 (23%), Positives = 112/296 (37%), Gaps = 26/296 (8%)
Query: 185 IRQVGETVNLQIPFQ----GKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
+R V ETV L + F G +W +G L DS V D + L I RS
Sbjct: 8063 LRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRS 8122
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTEL 298
+G+Y T A + +++ E PP IRL V TG +
Sbjct: 8123 LAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPI 8182
Query: 299 -LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
+ + + ++G + + + T+ + G+S + ++ N G S T
Sbjct: 8183 KVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVG-KDSCTAQLN 8241
Query: 358 LAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHT-STPGYSTQLFCSVRASPKPKIIWM 416
+ ++ PSFT+ L++ T G S +L V S + W
Sbjct: 8242 I-----------------KERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWY 8284
Query: 417 KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
KN +EIQ + L++RK D+G+YTCK N G A + +K
Sbjct: 8285 KNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPM---- 125
VP AP T+ V+ +S+TV+WE PE G + GY LE+ + W V+ P+
Sbjct: 16316 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 16375
Query: 126 MVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
+ V L G + RV A+++AG GP ++ P R+ I P P+
Sbjct: 16376 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPK 16428
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/104 (29%), Positives = 52/104 (50%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP AP + DV SV+++W P++ G + GY LE + W + P+ +
Sbjct: 20174 DVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMR 20233
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ RV A++ AG G P++ +P+ + I+ P
Sbjct: 20234 DFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 20277
Score = 57.8 bits (138), Expect = 2e-08
Identities = 48/208 (23%), Positives = 79/208 (37%), Gaps = 27/208 (12%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
I+ E+P PP + ++D +A L W P G + + GY+++ K + W +E
Sbjct: 28540 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW---VEAG 28596
Query: 321 H--PTTCTISDLIIGNSYSFRVFSENLCGLST-----SATVTKELAHIQKADIAAKPKGF 373
H T T+ L+ Y FRV ++N G S S+ + KE AD+
Sbjct: 28597 HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL 28656
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I T G + + P PK+ W +M ++ + +
Sbjct: 28657 I-----------------TCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTT 28699
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ TL ++ DSG Y N G
Sbjct: 28700 KDRTTLTVKDSMRGDSGRYFLTLENTAG 28727
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/98 (31%), Positives = 44/98 (44%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
+ ++ S+AP+F G + C + P P+I W KN + I +
Sbjct: 33126 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 33185
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ V +LEIR S DSG YT KA N G+ S L V
Sbjct: 33186 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/93 (30%), Positives = 44/93 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ L + T G S L C + P P + W + +I+ + ++ + G+ L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
R+ DSG +TC A+N G S C L V+ S
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 1035
Score = 57.4 bits (137), Expect = 3e-08
Identities = 55/218 (25%), Positives = 89/218 (40%), Gaps = 27/218 (12%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT-- 324
PGPPS + D + +L W PP G + + GY+V+ ++ T W V E T
Sbjct: 15705 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 15764
Query: 325 -CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
C + +L Y FRV + N G S + T E I DI +P+ FI+ +
Sbjct: 15765 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGE---IPATDIQEEPEVFIDIGAQDCL- 15820
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIW---------MKNKM-EIQGNPKYRALSE 433
G ++ ++ P PK W MK+ + +I + +
Sbjct: 15821 --------VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAEN 15872
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
V + K S +G Y+ A N G+ + +CR++V
Sbjct: 15873 SSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 15908
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 1/153 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P AP T+ V+ S V+W+PP G ++ Y LE + ++W+ V+ + T
Sbjct: 30825 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 30884
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
+V+NL G ++ RV + G + + +PI + ++ LR +R
Sbjct: 30885 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVR-YQS 30943
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMR 223
L G PKP W G + + + R
Sbjct: 30944 NATLVCKVTGHPKPIVKWYRQGKEIIADGLKYR 30976
Score = 56.6 bits (135), Expect = 5e-08
Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
+T +TVT++ +PK S P L D T + +
Sbjct: 32831 TTESTVTRK----------TEPKA--PEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGE 32878
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P+P IW K+ I KY+ ++G LEI K DSG+YTC N G S C+
Sbjct: 32879 PRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCK 32938
Query: 469 LEVKA 473
L +KA
Sbjct: 32939 LTIKA 32943
Score = 56.2 bits (134), Expect = 6e-08
Identities = 65/289 (22%), Positives = 108/289 (37%), Gaps = 23/289 (7%)
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
VG++ +LQ G P+ +W L + M + + L +DSG Y
Sbjct: 7974 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYIC 8033
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPS-SIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
E A + V E+ PPS S +L DV + G + +
Sbjct: 8034 KAENSVGEVSASTFLTVQEQKLPPSFSRQLRDV-----------QETVGLPVVFDCAISG 8082
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS--ENLCGLSTSATVTKELAHIQK 363
++ + W+ + + + + N+ + +F +L G S T T +
Sbjct: 8083 SEPISVSWYKDGKPLKDSP-NVQTSFLDNTATLNIFKTDRSLAG-QYSCTATNPIGS--- 8137
Query: 364 ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
A+ I + P F LA + G S C V + K+ W K+ EI+
Sbjct: 8138 ---ASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIR 8194
Query: 424 GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
KY+ + L + K DSG YTC A+N +G+ S +L +K
Sbjct: 8195 SGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIK 8243
Score = 55.8 bits (133), Expect = 8e-08
Identities = 57/237 (24%), Positives = 85/237 (35%), Gaps = 46/237 (19%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-T 323
+ P PP + + + + W PP G ++++GY+++K K +W E P
Sbjct: 14578 QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL 14637
Query: 324 TCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
T T L G Y FRV +EN G+S + T + D PK +
Sbjct: 14638 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPID---APKVILRTSLE---- 14690
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN--------------------KMEIQ 423
G L S+ SP P I W+K+ K E+Q
Sbjct: 14691 ---------VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQ 14741
Query: 424 GN-----PKYRAL----SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
P + L S++G L +R D G+Y K N G A C + V
Sbjct: 14742 EEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798
Score = 55.5 bits (132), Expect = 1e-07
Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 379 SEAPSFTQPL-ADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
+E P F + L A G S++L C + SP+ +++W +N+ E+ + KYR V
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 5479
Query: 438 TLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+++ S DSG + C+A N G S ++ VK
Sbjct: 5480 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 55.1 bits (131), Expect = 1e-07
Identities = 51/211 (24%), Positives = 84/211 (39%), Gaps = 26/211 (12%)
Query: 258 VIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
++ I I++PG P ++ + D L+W P G + L Y V++ K + W V
Sbjct: 18092 ILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH 18151
Query: 318 ERYHPTTCTISDLIIGNS-YSFRVFSENLCG----LSTSATVTKELAHIQKADIAAKPKG 372
+ T + D + N Y FRV ++N G + T V KE +QK + K G
Sbjct: 18152 KGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKE--DLQKPVLDLKLSG 18209
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK--MEIQGNPKYRA 430
+ T G + +L VR P P++ W K+K ++ +P+ +
Sbjct: 18210 VL-----------------TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 18252
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ + K D G Y A N G
Sbjct: 18253 DTRADSSKFSLTKAKRSDGGKYVVTATNTAG 18283
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PSAP+ LT+ +V SVT+SWEPP G + Y++E RE + T
Sbjct: 25197 DSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEK-RETTRKAYATITNNCTKT 25255
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ NL G + RV A + G G PA +P+ + E
Sbjct: 25256 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE 25294
Score = 54.7 bits (130), Expect = 2e-07
Identities = 30/94 (31%), Positives = 45/94 (47%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E P F +PL + G L C V +P+ +I W K +++ P Y+ + V +L
Sbjct: 7018 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 7077
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
I K D G Y+CKA N +G + L +KA
Sbjct: 7078 VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKA 7111
Score = 54.3 bits (129), Expect = 2e-07
Identities = 31/99 (31%), Positives = 43/99 (43%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
IE E P+F + L +L C V +P ++ W+KN EI+ + KY
Sbjct: 4947 IELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDR 5006
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
V L I K P D+G Y C N G S R+ +K
Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045
Score = 54.3 bits (129), Expect = 2e-07
Identities = 66/300 (22%), Positives = 110/300 (36%), Gaps = 47/300 (15%)
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
VG+ V LQ +G W + + +S + + + + L + +++G+Y
Sbjct: 7505 VGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYT 7564
Query: 246 LTVRVED--LEAKAVIDIL----VIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
++ + E A + +L ++EKP SI++ TG+T L
Sbjct: 7565 CQIKNDAGMQECFATLSVLEPATIVEKP---ESIKVT----------------TGDTCTL 7605
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL-------STSA 352
V + + +WF +L N Y F++ + GL S S
Sbjct: 7606 ECTVAGTPELSTKWFK----------DGKELTSDNKYKISFFNK-VSGLKIINVAPSDSG 7654
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
+ E+ + D +R + PSFT+ L + G S + C V SP
Sbjct: 7655 VYSFEVQNPVGKDSCTASLQVSDR--TVPPSFTRKLKETNGLSGSSVVMECKVYGSPPIS 7712
Query: 413 IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ W EI KY+ C L + DSG YTC A N+ G L V+
Sbjct: 7713 VSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR 7772
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/201 (20%), Positives = 82/201 (40%), Gaps = 13/201 (6%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+ + EKP PP + + + + +L W P+ G + ++ Y+V+ +K W
Sbjct: 26369 VKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA- 26427
Query: 321 HPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE 380
T +S L + Y FRVF+EN GLS + + ++ + E D
Sbjct: 26428 KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPP-------EIDMKN 26480
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
PS T + G + ++ + P PK+ ++ + ++ ++ T+
Sbjct: 26481 FPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTIN 26535
Query: 441 IRKPSPFDSGVYTCKAINVLG 461
+++ D+G Y A N G
Sbjct: 26536 LKESVTADAGRYEITAANSSG 26556
Score = 53.1 bits (126), Expect = 5e-07
Identities = 33/91 (36%), Positives = 38/91 (41%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
PSFT+ L S G L C V S I W K+ EI + KY+ LEI
Sbjct: 4675 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 4734
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ DSG YTC A N G L VK
Sbjct: 4735 SQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765
Score = 53.1 bits (126), Expect = 5e-07
Identities = 46/197 (23%), Positives = 82/197 (41%), Gaps = 16/197 (8%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT 324
+ PGP +++ V + ++ W P G + ++GY+V ++ +W V++
Sbjct: 19882 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQ 19939
Query: 325 CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ DL G Y+FRV +EN G T + +T + + D+ A + D P
Sbjct: 19940 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV----VARDDVVAP-----DLDLKGLPDL 19990
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
LA S + +L ++ P P + W K + + + + S TL +
Sbjct: 19991 CY-LAKENS----NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 20045
Query: 445 SPFDSGVYTCKAINVLG 461
D+G YT NV G
Sbjct: 20046 QKSDAGKYTITLKNVAG 20062
Score = 53.1 bits (126), Expect = 5e-07
Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
Query: 55 PTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P S A K P VPS P L + V+ S+T+ W PE G + GY++E + +
Sbjct: 25968 PLESVAIKALDPFT-VPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNS 26026
Query: 115 SEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WV V+ +P+ + L G ++ RV A ++AG P+ I + + P
Sbjct: 26027 LRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 26084
Score = 52.8 bits (125), Expect = 7e-07
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 380 EAPSFTQPL-ADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCT 438
E PSF + + + PG S +L C ++ SP ++ W KN E+ + R
Sbjct: 3735 EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 3794
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
L+I DSG Y+C+A+N +G S + +K
Sbjct: 3795 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 3828
Score = 52.8 bits (125), Expect = 7e-07
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 19/154 (12%)
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T + + + + R G Y ++ E +E ++ I I PGPP ++++ DV
Sbjct: 29897 TEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGM 29948
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV------LERYHPTTCTISDLIIGNSYS 337
L W PP+D G +++ GY+V++ + + +W V + RY T L G Y
Sbjct: 29949 TLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRST-----GLTEGLEYE 30003
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPK 371
RV + N G + +K + + KP+
Sbjct: 30004 HRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQ 30037
Score = 52.4 bits (124), Expect = 9e-07
Identities = 70/287 (24%), Positives = 106/287 (36%), Gaps = 28/287 (9%)
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ Q G P TW + LD V + D + L IRS SGRY +
Sbjct: 5064 SATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAK 5123
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
E + +LV E + +DV + T T L K K+
Sbjct: 5124 NESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPM---TLECVVAGTPELKVKWLKDGKQ 5180
Query: 310 T--GQWFTVLERYHPTTCTISDLIIGNS--YSFRVFSENLCGLSTSATVTKELAHIQKAD 365
++F++ + + I ++ +S Y+F+V EN G S+ + L
Sbjct: 5181 IVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV--ENDFGSSSCDAYLRVL------- 5231
Query: 366 IAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN 425
D + PSFT+ L G S + C V S W K+ EI +
Sbjct: 5232 -----------DQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280
Query: 426 PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
KYR + + +LE+ D+ YTCK NV G+ + L VK
Sbjct: 5281 AKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Score = 52.4 bits (124), Expect = 9e-07
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DV+ +S VSW PPE G + Y++E W V+ + T
Sbjct: 18697 DTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPE-VKKT 18755
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V NL G+++ RV+AV+ G G P + +P+ + + P PR L T + +
Sbjct: 18756 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPD--PPRKLEVTEMTKN 18813
Query: 189 GETV 192
T+
Sbjct: 18814 SATL 18817
Score = 52.4 bits (124), Expect = 9e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE+ V+ PGPP S+ + ++ + + W P G +E++GY+V+K D+
Sbjct: 23803 EPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSG 23862
Query: 311 GQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+W R ++ L + Y FRV +EN G+ + T
Sbjct: 23863 IRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 23908
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/91 (32%), Positives = 43/91 (47%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP T + H G +T+ +V++ P ++ W N +E+Q + K + GV TLE
Sbjct: 32373 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 32432
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
I DSG Y N GEAS L+V
Sbjct: 32433 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/287 (21%), Positives = 105/287 (36%), Gaps = 19/287 (6%)
Query: 200 GKPKPQATWTHNGHALDS---QRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAK 256
G PKP W +G L + +VS + L I D+G Y + VR + E
Sbjct: 1107 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1166
Query: 257 AVIDIL------VIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK- 309
A +L ++ K S +L A +Q +T G++ + +K+
Sbjct: 1167 ASASLLEEADYELLMK----SQQEMLYQTQVTAFVQEPKVGETAP----GFVYSEYEKEY 1218
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK 369
+ + ++ T + + + F E L + L + + D K
Sbjct: 1219 EKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEK 1278
Query: 370 PKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR 429
I + F + ++ G C + P PKI W K+ I+ +Y+
Sbjct: 1279 MAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQ 1338
Query: 430 A-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ G +L I P D G+YT A N+ G A +L V+ +A
Sbjct: 1339 MDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAA 1385
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/225 (24%), Positives = 85/225 (37%), Gaps = 30/225 (13%)
Query: 261 ILVIEKPGPPSSIRLL---DVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
IL ++ GPP+S L + L W P+ G + + GY+++K + V
Sbjct: 15286 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 15345
Query: 318 ERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIER 376
+R PTT + +L Y FRV + N G S + P + +
Sbjct: 15346 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNVVIQ 15389
Query: 377 DFSEAPSFTQPLADHTST----PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D P+ L+ T G + V P PKI W KN+ I+ ++
Sbjct: 15390 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 15449
Query: 433 EQGV------CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ V L I K D G YT A N LG + +EV
Sbjct: 15450 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 15494
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T+ DV+ S +SW+ PE G ++ Y +E WV V+ ++
Sbjct: 26276 DTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLS 26335
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+ V NL G + RVS + G G PA + + I E P+
Sbjct: 26336 YK-VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 26379
Score = 50.8 bits (120), Expect = 3e-06
Identities = 64/290 (22%), Positives = 105/290 (36%), Gaps = 24/290 (8%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+T L+ G P+ W +G L S + + ++ S L I + SDSG Y
Sbjct: 7600 GDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFE 7659
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
V+ + + V ++ PPS R L N +G++ ++ V +
Sbjct: 7660 VQNPVGKDSCTASLQVSDRTVPPSFTRKLKE--TNGL--------SGSSVVMECKVYGSP 7709
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ--KAD 365
+ WF H +++ G Y ++N C L+ + + +
Sbjct: 7710 PISVSWF------HEG----NEISSGRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIATN 7758
Query: 366 IAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN 425
+A + E PSF Q G + V+ +P + W K E+
Sbjct: 7759 MAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPG 7818
Query: 426 PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ E V LE+ SG YTC N G+AS L +KA A
Sbjct: 7819 DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA 7868
Score = 50.8 bits (120), Expect = 3e-06
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T DV+ S T+ W+ P G + YV+E W +S + T
Sbjct: 28447 DTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK---CT 28503
Query: 129 QQ--TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+Q V +LA G + RVSAV+ G G P + +PI E P+
Sbjct: 28504 RQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPR 28550
Score = 50.4 bits (119), Expect = 3e-06
Identities = 24/91 (26%), Positives = 46/91 (50%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P FTQ + + G L C + +P +++W+K++ +++ + K++ S+ +L I
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI 6517
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y CKA N +G + C ++ K
Sbjct: 6518 LNLEASDVGEYHCKATNEVGSDTCSCSVKFK 6548
Score = 50.4 bits (119), Expect = 3e-06
Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE++ V+ + P PP + + + + + W P G +E++ Y+V++ DK
Sbjct: 21639 EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAG 21698
Query: 311 GQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
+W ++ +S L G+ Y FR+ +EN G+S
Sbjct: 21699 QRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 21738
Score = 49.3 bits (116), Expect = 8e-06
Identities = 28/98 (28%), Positives = 43/98 (43%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
IE + AP + + G+ + C ++++P + W K EI + K S
Sbjct: 3448 IEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSS 3507
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ + +LEI + D G YTCKA N G S L V
Sbjct: 3508 KYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 3545
Score = 48.9 bits (115), Expect = 1e-05
Identities = 61/297 (20%), Positives = 112/297 (37%), Gaps = 38/297 (12%)
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQD 228
E PK + L + I + G++ L+ G P+ + W N H L S + M D
Sbjct: 5421 EPPKF--VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSV 5478
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKP----GPP--SSIRLLDVWGCN 282
+++ + + DSG + + ++V E P PP +++ +V
Sbjct: 5479 AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEV-SLE 5537
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L TPP E++ Y ++ + + ++ + +H T+ I ++ + + +
Sbjct: 5538 CELSGTPP-----FEVVWYKDKRQLRSSKKYKIASKNFH-TSIHILNVDTSDIGEYHCKA 5591
Query: 343 ENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
+N G T K E P F L T G +L
Sbjct: 5592 QNEVGSDTCVCTVK---------------------LKEPPRFVSKLNSLTVVAGEPAELQ 5630
Query: 403 CSVRASPKPKIIWMKNKME-IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN 458
S+ + + W+K K E I+ + R + V TL+ K P ++G Y C+ N
Sbjct: 5631 ASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKN 5687
Score = 48.5 bits (114), Expect = 1e-05
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 12/196 (6%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P+ L + +++ SV+++WEPP G ++ Y++E RE +
Sbjct: 23032 DTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK-REATRKSYAAVVTNCHKN 23090
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP-KIRVPRHLRQ----- 182
+ L G + RV+A + G G PA PI + E + P KI V R
Sbjct: 23091 SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLS 23150
Query: 183 -TYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF----IRSAQ 237
T G + +Q + + K W+ Q V + LF +
Sbjct: 23151 WTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKG 23210
Query: 238 RSDSGRYELTVRVEDL 253
RSD + + +DL
Sbjct: 23211 RSDPRSLAVPIVAKDL 23226
Score = 48.1 bits (113), Expect = 2e-05
Identities = 65/288 (22%), Positives = 98/288 (34%), Gaps = 21/288 (7%)
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRV-SMRTGDQDSILFIRSAQRSDSGRYEL 246
+GE LQ G P+ + +W L S M+ + + L I SD G Y
Sbjct: 7033 IGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSC 7092
Query: 247 TVRVEDLEAKAVIDILVIE--KPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
+ A A +LVI+ K P + +L DV E LG+ V
Sbjct: 7093 KAD-NSVGAVASSAVLVIKARKLPPFFARKLKDVH-----------------ETLGFPVA 7134
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKA 364
+ G + Y D + S+ V + + S +
Sbjct: 7135 FECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPL 7194
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
A+ I + P F G S C V + KI W K+ EI+
Sbjct: 7195 GTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRP 7254
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
Y+ + TL + K D+G YTC A N+ G+ S +L V+
Sbjct: 7255 GGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 48.1 bits (113), Expect = 2e-05
Identities = 60/295 (20%), Positives = 113/295 (38%), Gaps = 36/295 (12%)
Query: 175 RVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFI 233
R + L + I + E + G P+ + W + + +S + M D ++L +
Sbjct: 7306 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 7365
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIE------KPGPPSSIRLLDVWGCNAALQW 287
+ DSG Y A + + V E KP P +++ DV LQ
Sbjct: 7366 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVH-LECELQG 7424
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
TPP + + K + ++G+ + ++ T+ I ++ + ++ + N G
Sbjct: 7425 TPPFH------VSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVG 7478
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
T IA K P F + L+D ++ G QL ++
Sbjct: 7479 SDTCV-----------GSIALKAP----------PRFVKKLSDISTVVGKEVQLQTTIEG 7517
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALS-EQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ ++W K+K EI +S + + TL+ + P ++G YTC+ N G
Sbjct: 7518 AEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAG 7572
Score = 48.1 bits (113), Expect = 2e-05
Identities = 26/94 (27%), Positives = 44/94 (46%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E P F + + G L C ++ +P + W K+K E++ KY+ +SE + ++
Sbjct: 7397 EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSI 7456
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
I D G Y CKA N +G + + +KA
Sbjct: 7457 HILNVDAADIGEYQCKATNDVGSDTCVGSIALKA 7490
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
D++ SS ++WEPPE G + YVLE G ++PV + ++ TV++L +
Sbjct: 14490 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGE 14548
Query: 141 FLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ RV AV+ G G L P+ ++ + P
Sbjct: 14549 YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 14580
Score = 47.8 bits (112), Expect = 2e-05
Identities = 63/286 (22%), Positives = 107/286 (37%), Gaps = 47/286 (16%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G++ + G PK + +W +G+ + + Q+ + D + I A+ +SG Y
Sbjct: 4876 GQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCE 4935
Query: 248 VRVEDLEAKAVIDILVIEKPG------PPSSIRLLDVWGCNAALQWTPPQDTGNTELLGY 301
R + A I++ V E P P ++ DV + TPP + + +
Sbjct: 4936 ARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDV-ELECEVTGTPPFE------VTW 4988
Query: 302 MVQKADKKTGQWFTVLERY-----HPTTCTISDLIIGNSYSFRVFSEN-LCGLSTSATVT 355
+ + ++ + +T+ +R H T C SD Y V +E C ST +
Sbjct: 4989 LKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDT---GEYQCIVSNEGGSCSCSTRVAL- 5044
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
E PSF + + + T+ S +V SP I W
Sbjct: 5045 -----------------------KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITW 5081
Query: 416 MKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+K+ + + V TL+IR SG YTC+A N G
Sbjct: 5082 LKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 5127
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/199 (21%), Positives = 75/199 (37%), Gaps = 17/199 (8%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-KADKKTGQWFTVLERYHP 322
+ +P PP + + ++ +A L W PP G ++ GY+ + +++ +T
Sbjct: 18796 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 18855
Query: 323 TTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAP 382
+ ++ L G Y FRV + N G+S + +E + +A P P
Sbjct: 18856 LSLVVTGLKEGKKYKFRVAARNAVGVS----LPREAEGVYEAKEQLLP-----------P 18900
Query: 383 SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
P T G ++ V P P W K + E+ + L I+
Sbjct: 18901 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 18959
Query: 443 KPSPFDSGVYTCKAINVLG 461
+ DSG Y+ A N G
Sbjct: 18960 DVTRKDSGYYSLTAENSSG 18978
Score = 47.4 bits (111), Expect = 3e-05
Identities = 28/93 (30%), Positives = 41/93 (44%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E P F + L + G S L C + +P+ + W K +++ Y+ V TL
Sbjct: 7959 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8018
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ DSG Y CKA N +GE S L V+
Sbjct: 8019 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC--REGASEWVPVSARPMM 126
D P+ P+++ + + +S +SW+PP G + YV+E C +EGA EW VS+ +
Sbjct: 30724 DKPTGPIVI--EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGA-EWQLVSS-AIS 30779
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
VT + NL + RVSA ++ G P + + I+ E P
Sbjct: 30780 VTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP 30825
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + DVS SV ++W P G + Y++E C A W+ V T
Sbjct: 31120 DVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARET 31177
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
+ TV NL + RV A + G P+ +P +E+
Sbjct: 31178 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKED 31217
Score = 47.0 bits (110), Expect = 4e-05
Identities = 65/296 (21%), Positives = 99/296 (33%), Gaps = 42/296 (14%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ LQ+ F G + A W +G L + + D SIL I S ++ DSG Y
Sbjct: 4593 GDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE 4652
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
V+ + + I V++ PPS + L G+ L +V +
Sbjct: 4653 VQNDVGRSSCKARINVLDLIIPPSFTKKLK----------KMDSIKGSFIDLECIVAGSH 4702
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS-----------ATVTK 356
+ QWF ++ Y F F +N L S + T
Sbjct: 4703 PISIQWFK----------DDQEISASEKYKFS-FHDNTAFLEISQLEGTDSGTYTCSATN 4751
Query: 357 ELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWM 416
+ H Q + E P F + P QL V + I W
Sbjct: 4752 KAGHNQCSG---------HLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWF 4802
Query: 417 KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
K+ E+ + +LE+ DSG Y C+ N +G A+ L VK
Sbjct: 4803 KDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 83 SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP-----MMVTQQTVRNLAL 137
+ S+ VSW PP G + GY LE EG+ W VS P + + V L
Sbjct: 15611 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 15670
Query: 138 GDKFLLRVSAVSSAGAGPPAMLDQP 162
G K+ R A+++AG GPP+ P
Sbjct: 15671 GVKYQFRAMAINAAGIGPPSEPSDP 15695
Score = 47.0 bits (110), Expect = 4e-05
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 14/144 (9%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T P PPS + +V+ S+TV W P G + GY LE+ + W
Sbjct: 26668 TTPGPPSTP--------WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKA 26719
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + T V ++ G + RV A ++AG G P+ +P+ + E PR++
Sbjct: 26720 NKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP-----PRNV 26774
Query: 181 RQTYIRQVGETVNLQIP-FQGKPK 203
R T I + +++ Q P F G K
Sbjct: 26775 RITDISKNSVSLSWQQPAFDGGSK 26798
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T P P E + P +L DV+ SSV++SW P+ G + GY +E +WV
Sbjct: 30321 TPKTPLNPPEPPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWV 30377
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ + T TV L ++ R+ A + G + +P+ ++ + P
Sbjct: 30378 RHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKP 30431
Score = 46.6 bits (109), Expect = 5e-05
Identities = 39/129 (30%), Positives = 52/129 (40%), Gaps = 10/129 (7%)
Query: 355 TKELAHIQKADIAA---------KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
TKEL +K +A KP EAP + + T G V
Sbjct: 2042 TKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV 2101
Query: 406 RASPKPKIIWMKNKMEIQGNPK-YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P+ W KN ++I+ + + Y E VC L IR + DS KAIN+ GE S
Sbjct: 2102 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2161
Query: 465 VDCRLEVKA 473
L V+A
Sbjct: 2162 SHAFLLVQA 2170
Score = 46.6 bits (109), Expect = 5e-05
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ---GNPKYRALSEQGVCT 438
P FT PL + T+ G + + ++ P+P + W K+ +I+ + KY S++G+
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L I + D YT A N GE S +L V
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 46.2 bits (108), Expect = 6e-05
Identities = 42/153 (27%), Positives = 61/153 (39%), Gaps = 3/153 (1%)
Query: 20 ESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTL 79
E A++ TAE + + E R K A TA DVP P L +
Sbjct: 15863 EDAQLETAENSSVIIIPECKRSH-TGKYSITAKNKAGQKTANCRVKVM-DVPGPPKDLKV 15920
Query: 80 DDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGD 139
D++ S +SW+ P+ G ++GYV+E W V+ T V +L
Sbjct: 15921 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNP-DCGSTTFVVPDLLSEQ 15979
Query: 140 KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
++ RV A + G GPP Q R+ I P
Sbjct: 15980 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 16012
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/88 (27%), Positives = 43/88 (48%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + +++ S+TV W P+ G + GY++E W+ + R + +
Sbjct: 23818 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 23877
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPA 157
V L ++ RVSA ++AG G P+
Sbjct: 23878 LRVTGLTEDHEYEFRVSAENAAGVGEPS 23905
Score = 46.2 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
PSAP + VS++++++ WE P G + GY +E WV + P +
Sbjct: 28841 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 28900
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ R A+++AG + +PI + ++AP
Sbjct: 28901 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 28942
Score = 45.8 bits (107), Expect = 8e-05
Identities = 27/79 (34%), Positives = 36/79 (45%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G +TQL C V +P KI W N EI+ + K+R + L + DSG Y C+
Sbjct: 4314 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 4373
Query: 456 AINVLGEASVDCRLEVKAS 474
A N G + VK S
Sbjct: 4374 AQNEAGSDHCSSIVIVKES 4392
Score = 45.8 bits (107), Expect = 8e-05
Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 241 SGRYELTVRVED---LEAKAVIDILVIEKP----GPPSSIRLLDVWGCNAALQWTPPQDT 293
+G+YE VR + + + D +VI+ P GPP ++L + + WTPP D
Sbjct: 15566 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 15625
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTT--------CTISDLIIGNSYSFRVFSENL 345
G + + GY ++K ++ + W V P T + L+ G Y FR + N
Sbjct: 15626 GGSPITGYWLEKREEGSPYWSRVSRA--PITKVGLKGVEFNVPRLLEGVKYQFRAMAINA 15683
Query: 346 CGL 348
G+
Sbjct: 15684 AGI 15686
Score = 45.8 bits (107), Expect = 8e-05
Identities = 60/300 (20%), Positives = 105/300 (35%), Gaps = 40/300 (13%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ V G+P P+ W N + S VS+ L IR+A SDSG+Y +
Sbjct: 33148 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 33207
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG----YMV 303
+ + A ++V+ PS +L + +G+T L G V
Sbjct: 33208 AKNFRGQCSATASLMVLPLVEEPSREVVL--------------RTSGDTSLQGSFSSQSV 33253
Query: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSF--------RVFSENLCGLSTSATVT 355
Q + K F+ ++ T ++ S + S + G+S +
Sbjct: 33254 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 33313
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ + KA I P P +D + G + C+ P P++ W
Sbjct: 33314 SSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTW 33362
Query: 416 M--KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
K+ Q ++ + + TL I D G+YT N G S + +++
Sbjct: 33363 SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 33422
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/93 (24%), Positives = 42/93 (45%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E+P FT+ Y L V +P +I W K+ ++ KY+ + + +L
Sbjct: 4391 ESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSL 4450
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+I K D+G Y C+ N +G + R+ ++
Sbjct: 4451 QILKFVAADAGEYQCRVTNEVGSSICSARVTLR 4483
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P P + K D P P++ +DV+S+S+ V W P+ G + GY LE
Sbjct: 14885 PGPPCVSKPLVAKDPFGPPDAPDKPIV---EDVTSNSMLVKWNEPKDNGS-PILGYWLEK 14940
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
++ W V+ + + V L G ++ RV A ++AG G + P + I
Sbjct: 14941 REVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPI 15000
Query: 170 EAPKIRVPR 178
P +PR
Sbjct: 15001 SPPGPPIPR 15009
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/93 (30%), Positives = 41/93 (44%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E P Q L T G + + P+PKI W K + + K + L + TL
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + P D+ VYTC+A N G A+ L V+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329
Score = 45.1 bits (105), Expect = 1e-04
Identities = 20/72 (27%), Positives = 39/72 (54%)
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L C + +P +++W K+K +++ + KY+ S+ ++ I D G Y CKA N +
Sbjct: 5536 LECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEV 5595
Query: 461 GEASVDCRLEVK 472
G + C +++K
Sbjct: 5596 GSDTCVCTVKLK 5607
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+PL D T G + L C V + K+ W KN EI + KY +++ V L I
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 12345
Query: 444 PSPFDSGVYTCKA 456
+P D YTC A
Sbjct: 12346 CTPEDIKTYTCDA 12358
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGVCTL 439
P F + L + G ++ +P P I+W+KN I + PK R +G L
Sbjct: 1556 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1615
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+I DS YT AIN G + C++ V+ A
Sbjct: 1616 KIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFA 1652
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/77 (32%), Positives = 36/77 (46%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G ST C + +PK ++ W + EI K+ G+ T +I +SG Y C+
Sbjct: 4876 GQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCE 4935
Query: 456 AINVLGEASVDCRLEVK 472
A N G AS L+VK
Sbjct: 4936 ARNDAGTASCSIELKVK 4952
Score = 44.7 bits (104), Expect = 2e-04
Identities = 62/289 (21%), Positives = 109/289 (37%), Gaps = 32/289 (11%)
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
+ + L+ G P+ + W +G + S+ SM + + I+S + DSG+Y V
Sbjct: 5156 DPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV 5215
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ + + V+++ PPS + L T ++LG + K
Sbjct: 5216 ENDFGSSSCDAYLRVLDQNIPPSFTKKL----------------TKMDKVLGSSIHMECK 5259
Query: 309 KTG------QWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ 362
+G QWF + T+ + S S V N L +A T +++++
Sbjct: 5260 VSGSLPISAQWFKDGKEI-STSAKYRLVCHERSVSLEV---NNLELEDTANYTCKVSNVA 5315
Query: 363 KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI 422
D + G + E PSF + P + + ++ +P KI W K+ +E+
Sbjct: 5316 GDDACS---GIL--TVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVEL 5370
Query: 423 QGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
PK E L + +G YTC N +G S L V
Sbjct: 5371 VSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLV 5419
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/284 (20%), Positives = 102/284 (35%), Gaps = 42/284 (14%)
Query: 200 GKPKPQATWTHNGHALDSQRVSMRTGDQDS-ILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
G+P+P A WT +G A+ + D+ L I SDSG Y TV+
Sbjct: 32877 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--------- 32927
Query: 259 IDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
G SS L + + +TE QK + T Q V++
Sbjct: 32928 ------NSAGSVSSSCKLTI------------KAIKDTEAQKVSTQKTSEITPQKKAVVQ 32969
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
S+ I + S+ L A+ ++K+ + K + +
Sbjct: 32970 EEISQKALRSEEIKMSEAK----SQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 33025
Query: 379 SEAPSFTQPLADHTSTPGYSTQ--------LFCSVRASPKPKIIWMKNKMEIQGNPKYRA 430
++ ++ + H +STQ L + + W+ N +E+ + +YR
Sbjct: 33026 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 33085
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
TL I++ S D G+ TC I+ E V C+ ++ S
Sbjct: 33086 GVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDLTLS 33127
Score = 44.3 bits (103), Expect = 2e-04
Identities = 23/80 (28%), Positives = 38/80 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+F T+ G + + C+V +P + IW K+ + +P +R + LE+
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILEL 3610
Query: 442 RKPSPFDSGVYTCKAINVLG 461
+ D GVY+CKA N G
Sbjct: 3611 SNLTIQDRGVYSCKASNKFG 3630
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/93 (27%), Positives = 37/93 (39%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
+ P F + L S L C V K + W K+ ++ Y+ E + TL
Sbjct: 3642 DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 3701
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
EI DSG Y C A N G +S + V+
Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTVR 3734
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 379 SEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGV 436
++AP+FTQPL G + + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
L I + +SG Y+ KA N G+A+ L VKA A
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+F Q L T G +L V P P + + ++ EIQ + ++ E + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ P DSG Y+ A N +G A+ L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 43.1 bits (100), Expect = 5e-04
Identities = 62/287 (21%), Positives = 97/287 (33%), Gaps = 19/287 (6%)
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI--LFIRSAQRSDSGRYE 245
VG++V+LQ G P+ +W + G RT +++ L +DSG Y
Sbjct: 6092 VGDSVSLQCQVAGTPEITVSW-YKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYT 6150
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
A + + E+ PPS R L +D T +G V
Sbjct: 6151 CKAENSIGTASSKTVFRIQERQLPPSFARQL--------------KDIEQT--VGLPVTL 6194
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ G + Y D + S+ V + + S + +
Sbjct: 6195 TCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLG 6254
Query: 366 IAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN 425
A+ R+ ++P F G S C V + +I W K+ EI+
Sbjct: 6255 TASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPG 6314
Query: 426 PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
Y L I K DSG YTC+A N +G+ +L VK
Sbjct: 6315 GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 6361
Score = 42.4 bits (98), Expect = 0.001
Identities = 23/82 (28%), Positives = 39/82 (47%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E +F + L+DH+ PG S L + + + W K+ I + K ++ + C L
Sbjct: 5984 EPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCIL 6043
Query: 440 EIRKPSPFDSGVYTCKAINVLG 461
EI + D+G Y+C+ N G
Sbjct: 6044 EILNSTKRDAGQYSCEIENEAG 6065
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ PL D ++ G + C V + K+ W +I+ + +R + LEI
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
+ P D G YT A N +G+ S L ++A
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/96 (30%), Positives = 35/96 (36%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E PSF PG + L + + S I W K E+ E +L
Sbjct: 4204 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 4263
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
E+ DSG YTCK NV G L VK A
Sbjct: 4264 ELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA 4299
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 54 APTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
AP S A P ++ P P + +S + V W P G + GY LE +
Sbjct: 24489 APLDSKAVIVQYPFKE-PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ WV ++ P+ T+ L G ++ +VSA + G G P+ + + R+ + P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 24606
Score = 41.2 bits (95), Expect = 0.002
Identities = 67/326 (20%), Positives = 116/326 (35%), Gaps = 44/326 (13%)
Query: 156 PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL 215
P I + ++EAPKI ++ + Q G + ++ GKP P+ W NG +
Sbjct: 2062 PTFKPDKIELSPSMEAPKIF--ERIQSQTVGQ-GSDAHFRVRVVGKPDPECEWYKNGVKI 2118
Query: 216 DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRL 275
+ +D++ EL +R E A I + I G SS
Sbjct: 2119 ERSDRIYWYWPEDNVC-------------ELVIRDVTAEDSASIMVKAINIAGETSSHAF 2165
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
L V T EL + ++ D E + + +
Sbjct: 2166 LLVQAKQLI--------TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEG 2217
Query: 336 YSFRVFSE------NLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLA 389
+R+ S+ ++ + TS ++ ++ K +E E F + L
Sbjct: 2218 DKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVE---FVKELQ 2274
Query: 390 DHTSTPGYSTQLFCSVRASPKPKII---WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
D YS +L C V P+ I W N +E++ N KY S +G L ++ +
Sbjct: 2275 DIEVPESYSGELECIV----SPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTK 2330
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y+ V+ C+L++K
Sbjct: 2331 EDQGEYSF----VIDGKKTTCKLKMK 2352
Score = 41.2 bits (95), Expect = 0.002
Identities = 61/304 (20%), Positives = 107/304 (35%), Gaps = 37/304 (12%)
Query: 180 LRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQR 238
L + + + G+ L G P + TW N + +S + M + ++L +
Sbjct: 4305 LEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGI 4364
Query: 239 SDSGRYELTVRVEDLEAKAVIDILVIEKP------GPPSSIRLLDVWGCNAALQWTPPQD 292
DSG Y + E ++V E P P ++ DV A + TPP +
Sbjct: 4365 EDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVM-LLAEVAGTPPFE 4423
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST-S 351
+ + ++G+ + + H + I + ++ ++ N G S S
Sbjct: 4424 ------ITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICS 4477
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
A VT E PSF + + +S G + +++ S
Sbjct: 4478 ARVT----------------------LREPPSFIKKIESTSSLRGGTAAFQATLKGSLPI 4515
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ W+K+ EI + R E V +L + G Y C+A N G L V
Sbjct: 4516 TVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV 4575
Query: 472 KASA 475
K A
Sbjct: 4576 KEPA 4579
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/285 (21%), Positives = 104/285 (36%), Gaps = 56/285 (19%)
Query: 202 PKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVID 260
P + W +G L + + + L I + + D G Y V AK ++
Sbjct: 2646 PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVE 2705
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF---TVL 317
+ I+K +++ L V T QD T L + + K QW VL
Sbjct: 2706 AVKIKK-----TLKNLTV---------TETQDAVFTVELTH----PNVKGVQWIKNGVVL 2747
Query: 318 ERYHPTTCTISDLIIGNSYSFRV-----FSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
E ++ G YS R+ E++ G H++ I KPK
Sbjct: 2748 ESNEKYAISVK----GTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPK- 2802
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D T+ + SV P + W +EI+ + K+R +S
Sbjct: 2803 -----------------DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVS 2844
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
E+ V L ++ SP D+G YT V+G+ ++C+ ++ H
Sbjct: 2845 ERKVHKLMLQNISPSDAGEYTA----VVGQ--LECKAKLFVETLH 2883
Score = 40.4 bits (93), Expect = 0.004
Identities = 73/327 (22%), Positives = 114/327 (34%), Gaps = 40/327 (12%)
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVS 221
++I+E + P + L +T G + L+ G W N + +
Sbjct: 8240 LNIKERLIPPSFT--KRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCE 8297
Query: 222 MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGC 281
+ + +L +R A +D+G Y V + A I++ E PP + L
Sbjct: 8298 ITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHL----- 8352
Query: 282 NAALQWTPPQ-DTGNTELLGYMVQKADKKTGQWFTVLERYHPTT-CTIS----------- 328
TP G L VQ ++ QW P+ C+ S
Sbjct: 8353 ------TPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELR 8406
Query: 329 DLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERD--FSEAPSFTQ 386
D+ +S + + N+ G T T +K + A A K ++ F P +
Sbjct: 8407 DVAKADSGDYVCKASNVAGSDT--TKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIR 8464
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQ--GVCTLEIRKP 444
+ T+T V P P + W K K Q N R Q LEIR
Sbjct: 8465 VVEKTTAT------FIAKVGGDPIPNVKWTKGKWR-QLNQGGRVFIHQKGDEAKLEIRDT 8517
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
+ DSG+Y C A N GE + L+V
Sbjct: 8518 TKTDSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 40.4 bits (93), Expect = 0.004
Identities = 19/61 (31%), Positives = 29/61 (47%)
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ W +++ + KY E GV L ++ + D G Y CK +N GE S L V
Sbjct: 31599 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Query: 472 K 472
K
Sbjct: 31659 K 31659
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/126 (24%), Positives = 44/126 (34%), Gaps = 6/126 (4%)
Query: 350 TSATVTKELAHIQKADIAAKPKGFIERDFSE----APSFTQPLADHTSTPGYSTQLFCSV 405
T T+E ++ D+ E AP F G S C V
Sbjct: 1046 TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV 1105
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+PKP + W K+ + + +Y+ + G C L I D+G YT N GE
Sbjct: 1106 GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGET 1165
Query: 464 SVDCRL 469
S L
Sbjct: 1166 SASASL 1171
Score = 40.0 bits (92), Expect = 0.005
Identities = 41/151 (27%), Positives = 63/151 (41%), Gaps = 11/151 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L L D++ SVT+ W+ P G + Y++E RE + +
Sbjct: 20866 DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEK-REATRKSYSTATTKCHKC 20924
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V L+ G ++ RV A + G G P +P+ + EAP P L I +
Sbjct: 20925 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV---KASEAPS--PPDSLNIMDITK- 20978
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
TV+L P KPK G+ +++QR
Sbjct: 20979 -STVSLAWP---KPKHDGGSKITGYVIEAQR 21005
Score = 39.3 bits (90), Expect = 0.008
Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR---VSMRTGDQDSILFIRSAQR 238
Q+ + G T + G P P+ +W +G + + V + D + L I + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 239 SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL 276
++SGRY L +A + ++LV + PP+ ++ L
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110
Score = 38.9 bits (89), Expect = 0.010
Identities = 59/291 (20%), Positives = 105/291 (36%), Gaps = 34/291 (11%)
Query: 192 VNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
V+L+ G P + W + L S++ + + + + + I + SD G Y +
Sbjct: 5534 VSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 5593
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E V + + E P S + L V G L ++ A
Sbjct: 5594 EVGSDTCVCTVKLKEPPRFVSKLNSLTVVA-------------GEPAELQASIEGAQPIF 5640
Query: 311 GQWFTVLERYHPTTCTISDLIIGNSYSFRV-FSENLCGLSTSATVTKELAHIQKADIAAK 369
QW E +I S + R+ F EN+ L + E A+ K K
Sbjct: 5641 VQWLKEKEE-----------VIRESENIRITFVENVATLQFAKA---EPANAGKYICQIK 5686
Query: 370 PKGFIERDFS-----EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
G + + + E + T T G + L C V +P+ + W K+ +
Sbjct: 5687 NDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTS 5746
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ K++ + +L I D+G YT + N +G++S ++V A
Sbjct: 5747 SQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 5797
Score = 38.5 bits (88), Expect = 0.014
Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 26/144 (18%)
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSIL 231
P+ +P + + Y VGE V + P+P TW +G ++ GD D
Sbjct: 31690 PEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIKPGDNDK-- 31737
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT--- 288
+ SD G Y+LT+ + A ++ K G S C A L T
Sbjct: 31738 --KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS---------CKAKLTVTLHP 31786
Query: 289 PPQDTGNTELLGYMVQKADKKTGQ 312
PP D+ + ++ A+ + GQ
Sbjct: 31787 PPTDSTLRPMFKRLLANAECQEGQ 31810
Score = 38.1 bits (87), Expect = 0.018
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 14 PEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSA 73
PEE KVP PP EV + KP+AP P+ P A K P + VP
Sbjct: 10485 PEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVP---EAPKEVVPEKKVPVP 10541
Query: 74 P 74
P
Sbjct: 10542 P 10542
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 1/97 (1%)
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE-QG 435
D + P F + LA+ G S V P P + W K+ + P + E
Sbjct: 31790 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 31849
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
L IR P D+G Y A N G S L+V+
Sbjct: 31850 YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Score = 37.7 bits (86), Expect = 0.023
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 4/80 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
GE+ G+P P TW G L S R + T S I S Q SD G Y +
Sbjct: 32575 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY--S 32632
Query: 248 VRVEDLEAKAVIDI-LVIEK 266
V VE+ E K + L I+K
Sbjct: 32633 VVVENSEGKQEAEFTLTIQK 32652
Score = 36.6 bits (83), Expect = 0.051
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTC 325
PG P + V + + W P+ G + + GY ++ D + +W V + T
Sbjct: 16317 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 16376
Query: 326 TIS----DLIIGNSYSFRVFSENLCGLSTSA 352
+S LI G+ Y FRV++ N G+ ++
Sbjct: 16377 GVSYKVTGLIEGSDYQFRVYAINAAGVGPAS 16407
Score = 36.6 bits (83), Expect = 0.051
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PP D P P + T ++ S+ V W P+ G + Y++E + W+ + +
Sbjct: 21654 PP--DPPKNPEVTT---ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 21708
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPA 157
+ + V L G ++ R+ A ++AG P+
Sbjct: 21709 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 21741
Score = 36.2 bits (82), Expect = 0.067
Identities = 70/293 (23%), Positives = 107/293 (36%), Gaps = 41/293 (13%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI--LFIRSAQRSDSGRYEL 246
G LQ G + +W + + S + R Q S+ L I S +D G YE
Sbjct: 3845 GTNALLQCEVSGTGPFEISWFKDKKQIRSSK-KYRLFSQKSLVCLEIFSFNSADVGEYEC 3903
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLD--------VWGCNAALQWTPPQDTGNTEL 298
V E + + L+ E PP+ ++ +D AA++ + P T +
Sbjct: 3904 VVANEVGKCGCMATHLLKE---PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISV--TWM 3958
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKEL 358
G V + D K F+ I D+ I + +EN G TS EL
Sbjct: 3959 KGQEVIREDGKIKMSFS----NGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVG---EL 4011
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
I +P IER Q A +T Y+ V +P+ K W K+
Sbjct: 4012 -------IVKEPAKIIER-----AELIQVTAGDPATLEYT------VAGTPELKPKWYKD 4053
Query: 419 KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ + KYR + V L+ DSG YT + N +G +S + V
Sbjct: 4054 GRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV 4106
Score = 35.8 bits (81), Expect = 0.088
Identities = 18/64 (28%), Positives = 30/64 (46%)
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P + W+ + ++ + R ++E G C+L+ DSG+ TC+A N G
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791
Query: 469 LEVK 472
L VK
Sbjct: 1792 LIVK 1795
Score = 35.8 bits (81), Expect = 0.088
Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 3/134 (2%)
Query: 42 EQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGR 99
E + + +A P ++P A S +PS P + + + W PE G
Sbjct: 29209 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 29268
Query: 100 LGLQGYVLELCREGASEWVPVSARPMMV-TQQTVRNLALGDKFLLRVSAVSSAGAGPPAM 158
+ Y+++ + + W V+ ++ T+ V +L G + RV+AV++AG P+
Sbjct: 29269 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 29328
Query: 159 LDQPIHIRENIEAP 172
I RE P
Sbjct: 29329 ASNFISCREPSYTP 29342
Score = 35.8 bits (81), Expect = 0.088
Identities = 54/291 (18%), Positives = 98/291 (33%), Gaps = 34/291 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + Q KP + W HNG L +S ++ L I DSG Y
Sbjct: 32388 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRA- 32446
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
+ G S LDV G + + +D ++
Sbjct: 32447 --------------VCTNYKGEASDYATLDVTGGDYTTYASQRRD-----------EEVP 32481
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS------ENLCGLSTSATVTKELAHI 361
+ T E Y ++ + + +S V S E+L SA+ + A +
Sbjct: 32482 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 32541
Query: 362 QKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
++ + K + A T+P + T G S + C P P + W++
Sbjct: 32542 EEKSLEEKSTTRKIKTTLAARILTKPRS-MTVYEGESARFSCDTDGEPVPTVTWLRKGQV 32600
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + +++ + + T EI D G Y+ N G+ + L ++
Sbjct: 32601 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 35.4 bits (80), Expect = 0.11
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 3 EKNTSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATK 62
EK P PE ++ +VP A P + E PKP++P P+ P A K
Sbjct: 10535 EKKVPVPPPKKPEVPPTKVPEVPKAAVP-----EKKVPEAIPPKPESPPPEVP---EAPK 10586
Query: 63 PAPPSEDVPSAP 74
P + VP+AP
Sbjct: 10587 EVVPEKKVPAAP 10598
Score = 35.0 bits (79), Expect = 0.15
Identities = 37/142 (26%), Positives = 56/142 (39%), Gaps = 14/142 (9%)
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
WF + H T+ T+ G ++ + L +S KEL+ + +
Sbjct: 11606 WFKNDAKLH-TSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKV------ 11658
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+E D P FT L D T+ L C V S + W K+ EI +PKY +
Sbjct: 11659 -LEAD----PYFTVKLHDKTAVEKDEITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIKA 11711
Query: 433 EQGVCTLEIRKPSPFDSGVYTC 454
+ L+I+K D G Y C
Sbjct: 11712 DGLRRILKIKKADLKDKGEYVC 11733
Score = 35.0 bits (79), Expect = 0.15
Identities = 63/289 (21%), Positives = 114/289 (39%), Gaps = 40/289 (13%)
Query: 173 KIRVPRHLRQTYIRQVGETV-NLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSI 230
K+R+ L+ T +++ E V N ++ +G +A W N A+ DS + + D
Sbjct: 12639 KLRIVVPLKDTRVKEQQEVVFNCEVNTEGA---KAKWFRNEEAIFDSSKYIILQKDLVYT 12695
Query: 231 LFIRSAQRSDSGRYELTVRVEDLE-AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L IR A D Y +++ E K+ +++V E+ +R+++ P
Sbjct: 12696 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE-----DLRIVE-----------P 12739
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPT---TCTISDLIIGNSYSFRVFSENLC 346
+D ++ +KK+ ++ + R + T T ++ N S+RV
Sbjct: 12740 LKD----------IETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHM 12789
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS-FTQPLADHTSTPGYSTQLFCSV 405
E +I A + K E EAP+ F + L D T T + +F
Sbjct: 12790 LTIKDCGFPDEGEYIVTA---GQDKSVAELLIIEAPTEFVEHLEDQTVTE-FDDAVFSCQ 12845
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
+ K + W +N EI+ KY+ + + L I+ D Y C
Sbjct: 12846 LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 12894
Score = 34.7 bits (78), Expect = 0.20
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTC 454
G + + V P P+ W + +I + ++ + E G +L I +P DSG +T
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTV 1530
Query: 455 KAINVLGEASVDCRLEVKA 473
A N G +S+ L V+A
Sbjct: 1531 VAQNRAGRSSISVILTVEA 1549
Score = 34.7 bits (78), Expect = 0.20
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E FT+ LA+ + + +L C V + P ++IW K EI +Y L+E L
Sbjct: 12461 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 12519
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I+ D+G Y C+ L + D +++V AA
Sbjct: 12520 VIQNAHLEDAGNYNCR----LPSSRTDGKVKVHELAA 12552
Score = 34.3 bits (77), Expect = 0.26
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI--LFIRSAQRSDSGRY 244
GE+V L+ G P P TW + ++S + + Q I L IR A DSGR+
Sbjct: 957 GESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARLMIREAFAEDSGRF 1013
Score = 34.3 bits (77), Expect = 0.26
Identities = 37/149 (24%), Positives = 53/149 (35%), Gaps = 8/149 (5%)
Query: 328 SDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIER-----DFSEAP 382
SD I + F N+ L S E+ H K AK I+R E
Sbjct: 4523 SDEITEDDNIRMTFENNVASLYLSGI---EVKHDGKYVCQAKNDAGIQRCSALLSVKEPA 4579
Query: 383 SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
+ T+ T G L + + W K+ E+ KY+ V L+I
Sbjct: 4580 TITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKII 4639
Query: 443 KPSPFDSGVYTCKAINVLGEASVDCRLEV 471
DSG YT + N +G +S R+ V
Sbjct: 4640 STEKKDSGEYTFEVQNDVGRSSCKARINV 4668
Score = 34.3 bits (77), Expect = 0.26
Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 392 TSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGV 451
T T G L C V +P+ W K+ E+ + K+ V +L+I D G+
Sbjct: 6655 TVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGL 6714
Query: 452 YTCKAINVLGEASVDCRLEVKAS 474
Y+ + N +G++ +C + V S
Sbjct: 6715 YSFEVKNSVGKS--NCTVSVHVS 6735
Score = 34.3 bits (77), Expect = 0.26
Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 5/69 (7%)
Query: 10 PACSPEETASESAKVPTAEPPGEVAVS-ESTREEQV---PKPQAPAPQAPTASTATKPAP 65
P P E E +V EPP EV E QV PK P +AP A A KP
Sbjct: 10658 PESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAP-AVVAKKPEL 10716
Query: 66 PSEDVPSAP 74
P VP P
Sbjct: 10717 PPVKVPEVP 10725
Score = 34.3 bits (77), Expect = 0.26
Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P + + +VS SVT++WE P G + Y++E RE A T
Sbjct: 29536 DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK-REAAMRAFKTVTTKCSKT 29594
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ L G + RV + G G P + + E
Sbjct: 29595 LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 29633
Score = 33.9 bits (76), Expect = 0.33
Identities = 55/255 (21%), Positives = 94/255 (36%), Gaps = 49/255 (19%)
Query: 208 WTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
WT NG + RVS R +L I+ D G Y +T + K+V ++L+IE
Sbjct: 12766 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQD----KSVAELLIIEA 12821
Query: 267 PGP------PSSIRLLD--VWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
P ++ D V+ C + + + N G +++ K + +
Sbjct: 12822 PTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRN----GREIKEGKKYKFEKDGSIH 12877
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
R C + D E CG+ D ++ + F+E
Sbjct: 12878 RLIIKDCRLDDEC-----------EYACGVE---------------DRKSRARLFVE--- 12908
Query: 379 SEAP-SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
E P +P D PG +F + K ++ W++N M + K++ +SE +
Sbjct: 12909 -EIPVEIIRPPQDILEAPGADV-VFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIH 12966
Query: 438 TLEIRKPSPFDSGVY 452
L+I P D G Y
Sbjct: 12967 RLQICDIKPRDQGEY 12981
Score = 33.5 bits (75), Expect = 0.44
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P++ + L D T G + + C P K W +N ++ +++ E V L I
Sbjct: 8745 PAWERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTI 8803
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
D G YTCK ++ E S + R+E +
Sbjct: 8804 ADVRAEDQGQYTCKYEDL--ETSAELRIEAE 8832
Score = 32.7 bits (73), Expect = 0.74
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 4/62 (6%)
Query: 13 SPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPS 72
+P+E E KVP PP + T+ +VPK P + P A KP P +VP
Sbjct: 10528 APKEVVPEK-KVPV--PPPKKPEVPPTKVPEVPKAAVPEKKVPEA-IPPKPESPPPEVPE 10583
Query: 73 AP 74
AP
Sbjct: 10584 AP 10585
Score = 32.7 bits (73), Expect = 0.74
Identities = 31/114 (27%), Positives = 41/114 (35%), Gaps = 32/114 (28%)
Query: 14 PEETASESAKVPTAEPPGEVAVSESTR---------------EEQVP---KPQAPAPQAP 55
PEE A E P E P VA E E++VP KP+AP P+ P
Sbjct: 10807 PEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEP 10866
Query: 56 TASTATK------------PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERL 97
+ PAPP EDV + L + V + PE++
Sbjct: 10867 EPEKVIEKPKLKPRPPPPPPAPPKEDVKEK--IFQLKAIPKKKVPEKPQVPEKV 10918
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 4/77 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G+T + G+P P+ W H+G + D + D L I A SDSG E
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG--EW 1528
Query: 247 TVRVEDLEAKAVIDILV 263
TV ++ ++ I +++
Sbjct: 1529 TVVAQNRAGRSSISVIL 1545
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G + + C V P+PK+ W N I+ + ++R + G+ L+I +D+G
Sbjct: 1855 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1913
Query: 456 AINVLGEASVDCRLEVK 472
A N G +LE++
Sbjct: 1914 AENPEGVIEHKVKLEIQ 1930
Score = 30.8 bits (68), Expect = 2.8
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 12/99 (12%)
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ--RVSMRTGDQ 227
E IRV T+I +VG G P P WT +Q RV +
Sbjct: 8459 EPQSIRVVEKTTATFIAKVG----------GDPIPNVKWTKGKWRQLNQGGRVFIHQKGD 8508
Query: 228 DSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
++ L IR ++DSG Y E E ++ +++ V E+
Sbjct: 8509 EAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 8547
Score = 30.4 bits (67), Expect = 3.7
Identities = 63/326 (19%), Positives = 120/326 (36%), Gaps = 54/326 (16%)
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T ++L++ D +RV A+ + +L+ + + Q Y +
Sbjct: 11986 TFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKL------------QDYTGVEKD 12033
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
V LQ P W +G + S+ ++ + +L ++ A +SD G+Y
Sbjct: 12034 EVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCG 12092
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG-YMVQKAD- 307
+ K I+ I+ P S+ +++ + + N +L G ++Q D
Sbjct: 12093 TDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDC 12152
Query: 308 --KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ-KA 364
K+ G+ I L++ N C L + V + A+++ A
Sbjct: 12153 EIKEEGK--------------IHSLVLHN-----------CRLDQTGGVDFQAANVKSSA 12187
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
+ KP+ +PL D T T G + C + P ++K K +++
Sbjct: 12188 HLRVKPR---------VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGK-KLEP 12237
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSG 450
+ K SE V TL +R D+G
Sbjct: 12238 SDKVVPRSEGKVHTLTLRDVKLEDAG 12263
Score = 30.4 bits (67), Expect = 3.7
Identities = 34/160 (21%), Positives = 60/160 (37%), Gaps = 10/160 (6%)
Query: 13 SPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDV-- 70
S ET E EV+ SE+ E +PK T + + + +V
Sbjct: 15433 SKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHV 15492
Query: 71 -----PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSAR 123
PS P L + D+ + S ++W+ P G + YV++ +EW V+
Sbjct: 15493 EVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT-N 15551
Query: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
+ + + L ++ RV AV+ G D+ +
Sbjct: 15552 TAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 15591
Score = 30.0 bits (66), Expect = 4.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F +PL D + C + + K+ W K+ EI+ KY +S+ V L I K
Sbjct: 12376 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 12434
Query: 444 PSPFDSGVYTCK 455
D Y+C+
Sbjct: 12435 CLLDDEAEYSCE 12446
Score = 29.3 bits (64), Expect = 8.2
Identities = 20/86 (23%), Positives = 33/86 (38%), Gaps = 4/86 (4%)
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
PL D G L C V + W N +I+ + + +A+ + L I +
Sbjct: 2450 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2509
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y ++G +C L V+
Sbjct: 2510 SDEGPYKL----IVGRVETNCNLSVE 2531
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 155 bits (392), Expect = 8e-38
Identities = 92/303 (30%), Positives = 156/303 (51%), Gaps = 15/303 (4%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
PA A + + +P PP + +TL DV+ +SV++SWE PE G + GY++E+
Sbjct: 15731 PAETAESVKASERPLPPGK--------ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15782
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
+G+ +W + + VT+ T+ L G+++ RVSA + G P L P+ ++ +
Sbjct: 15783 QTKGSDKWATCAT--VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 15840
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQD 228
P ++ L T+ GE + + +PF G+P P TW + L + RV+ + + +
Sbjct: 15841 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 15897
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQW 287
S+L I+ A R D G Y + + EA ++++V++KPGPP+ +++ +V + L W
Sbjct: 15898 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 15957
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G + + Y+V+K D T W V TT L G Y FR+ +EN G
Sbjct: 15958 GPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYG 16017
Query: 348 LST 350
ST
Sbjct: 16018 KST 16020
Score = 155 bits (392), Expect = 8e-38
Identities = 92/291 (31%), Positives = 146/291 (50%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A + + PS P +TL DVS +S ++ WE PE G + GYV+E+ +G +W V
Sbjct: 17898 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17957
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ V V L+ G ++ RV A + G P +L P+ ++ P +++P +
Sbjct: 17958 AESK--VCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN- 18014
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
TY Q GE + ++IP G+P+P +W +G L + RV++ ++L I+ +
Sbjct: 18015 --TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKD 18072
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTEL 298
D G+Y +T A + ++V+EKPGPP +R +V + W PP TG ++
Sbjct: 18073 DFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQI 18132
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+V+K D T W V TT I+ L G Y FR+F+EN G S
Sbjct: 18133 SNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 18183
Score = 155 bits (392), Expect = 8e-38
Identities = 96/325 (29%), Positives = 162/325 (49%), Gaps = 9/325 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR-PMMV 127
D P P + + D + SS+T+ W P G + GYV+E+ + EW VS + +
Sbjct: 20860 DPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRT 20919
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ V NL G + RVSAV+ AG G P +++P+ ++ +EAP+I + LR + I +
Sbjct: 20920 TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAK 20979
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRSDSGRYEL 246
GE V + IPF+G+P P TW + L S R S+ D S+L I R+D+G+Y L
Sbjct: 20980 AGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYIL 21039
Query: 247 TVRVEDLEAK-AVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
T+ E K + + + V++ P +++ V L W PP G + ++ Y+++K
Sbjct: 21040 TIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEK 21099
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
D W V + T+ + DL + FRV +EN G+ T+ ++ A+
Sbjct: 21100 RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP---VKAAE 21156
Query: 366 IAAKPKGFIERDFSEAP---SFTQP 387
+ A + +D ++ S+T+P
Sbjct: 21157 VPAPIRDLSMKDSTKTSVILSWTKP 21181
Score = 154 bits (389), Expect = 2e-37
Identities = 121/445 (27%), Positives = 189/445 (42%), Gaps = 28/445 (6%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V KP A P A +P+PP LT D + SSV + WEPP + G +
Sbjct: 6968 VGKPSAATPFVKVADPIERPSPPVN--------LTSSDQTQSSVQLKWEPPLKDGGSPIL 7019
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
GY++E C EG W+ + + + V L G+K+L RVSA + AG P+ + P+
Sbjct: 7020 GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPL 7079
Query: 164 HIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSM 222
+ P + + + V + + +P G P+P ATW L++ RV M
Sbjct: 7080 TADDAFVEPTMDLSAFKDGLEVI-VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKM 7138
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
+T + L I ++RSD G Y L + ID+ VI +P P ++ D+ +
Sbjct: 7139 KTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDS 7198
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP D G + L GY+V+K + W V++ T+ DL+ G Y F+V +
Sbjct: 7199 VHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCA 7258
Query: 343 ENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
N CG A V + + A + P+ RD + F D G S
Sbjct: 7259 RNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL--TWDPPKNDGGSRIKG 7316
Query: 403 CSVRASPKPKIIWM-------KNKMEIQGNP-------KYRALSEQGVCTLEIRKPSPFD 448
V P+ W+ + KME+ G + +AL+ QG + +P+
Sbjct: 7317 YIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS--KPSRPTEEI 7374
Query: 449 SGVYTCKAINVLGEASVDCRLEVKA 473
V T +A + + + L VKA
Sbjct: 7375 QAVDTQEAPEIFLDVKLLAGLTVKA 7399
Score = 154 bits (388), Expect = 2e-37
Identities = 82/278 (29%), Positives = 141/278 (50%), Gaps = 1/278 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P ++ + D S ++V++ W P G + + GY++E+C+ +W V+A + T+
Sbjct: 21949 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRY 22008
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV +L G+++ RVSA++ AG G + I + + AP++ + + +QT++ + G
Sbjct: 22009 TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGA 22068
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
++ L I +QG+P P A W+ L S R + T D S L + + R+D+G+Y LTV
Sbjct: 22069 SIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVEN 22127
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
+ V++ PGPP I DV +A L W P G + Y+V+K +
Sbjct: 22128 NSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASR 22187
Query: 311 GQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
W + E+ ++DL G Y FRV + N G+
Sbjct: 22188 RSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGV 22225
Score = 153 bits (386), Expect = 4e-37
Identities = 88/291 (30%), Positives = 151/291 (51%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE P P +TL DV+ ++ T+ WE PE G + GYV+E+ +G+ +W
Sbjct: 18982 TEPVKVSEP-PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-- 19038
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + T+ L G++++ RV+AV+ G P L P+ R+ P + +P H
Sbjct: 19039 TCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH- 19097
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
T+ + E + + +PF+G+P+ W +G L ++ RV++ + + L I+ A +
Sbjct: 19098 --TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKE 19155
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
D G YEL V I I+V+++PGPP IR+ +V + + W PP+ G ++
Sbjct: 19156 DVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQIS 19215
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
Y+V+K + + W V + T+ I L G+ Y FRV +EN G S+
Sbjct: 19216 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSS 19266
Score = 152 bits (384), Expect = 6e-37
Identities = 89/283 (31%), Positives = 147/283 (51%), Gaps = 7/283 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
+VP P +T+DDV+ +SV++SW PE G + Y++E+ + + +W + +
Sbjct: 16824 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSL-- 16881
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
Q + NL G+++L RV AV+ G P L PI ++ + P ++ +Y QV
Sbjct: 16882 QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF---SSYSVQV 16938
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + +++P G+PKP TWT +G L + R+++ + L I+ + D G+Y +T
Sbjct: 16939 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 16998
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
V + A I+I+ ++KP PP ++ DV + L W PP TG ++ Y+VQK
Sbjct: 16999 VANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKR 17058
Query: 307 DKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D T W V TT ++ L G Y FR+F+EN G S
Sbjct: 17059 DTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17101
Score = 149 bits (375), Expect = 7e-36
Identities = 90/292 (30%), Positives = 144/292 (49%), Gaps = 2/292 (0%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A +VP P L + DV+ S+VT++WE P G L GYVLE C+ G W+ V
Sbjct: 23320 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 23379
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
V + TV +L G+++L R+ A + G P + +++ P I +
Sbjct: 23380 VTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 23439
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++T G V L IP G+P P A+W G L +S+RV++ T + + L IR
Sbjct: 23440 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 23499
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G Y L ++ I +++++KPGPP+ I++ ++ + + W PP+ G L
Sbjct: 23500 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 23559
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
GY+V++ D W V E +T + L GN Y FRV + N G+ +
Sbjct: 23560 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 23611
Score = 145 bits (367), Expect = 6e-35
Identities = 109/371 (29%), Positives = 175/371 (47%), Gaps = 16/371 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE PS P L + D++ S+V+++W P+ G + GYV+E R+G+ +W +
Sbjct: 14651 TEPVKASE-APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14709
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + VRNL G+++ +V AV+SAG P +P+ ++E P++ +
Sbjct: 14710 TT--VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTMLPELDLRGIY 14766
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++ I + G+ + ++IP G+PKP TW L +QRV+ T +IL I RS
Sbjct: 14767 QKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRS 14826
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
DSG Y LT R E VI I V + PGPP+ I+ +V W PP++ G +
Sbjct: 14827 DSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 14886
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y+V+ + W + TT + L G Y FRV ++N G+ TSA +
Sbjct: 14887 SNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIV 14946
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ +D S S+ +PL+D G S L V + I+W
Sbjct: 14947 ANYPFKVPGPPGTPQVTAVTKD-SMTISWHEPLSD-----GGSPILGYHVERKERNGILW 15000
Query: 416 MK-NKMEIQGN 425
+K + GN
Sbjct: 15001 QTVSKALVPGN 15011
Score = 145 bits (366), Expect = 8e-35
Identities = 94/331 (28%), Positives = 158/331 (47%), Gaps = 19/331 (5%)
Query: 49 APAPQAP---TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
AP+P +P T KP PP P +L D S SS++++W P G + GY
Sbjct: 15434 APSPTSPFYKACDTVFKPGPPGN-----PRVL---DTSRSSISIAWNKPIYDGGSEITGY 15485
Query: 106 VLELCREGASEW-VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E+ EW + + T T+ L ++ +R+ A++S G G PA++
Sbjct: 15486 MVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 15545
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMR 223
+ + P+I + LR+ + T+ L +P +G+P P+ W +G +LD + S+
Sbjct: 15546 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 15603
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ ++L + + R DSG+Y LTV A +++ V++ PGPP +++ +V +
Sbjct: 15604 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15663
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L W PP G +++ Y+V+K + + TV H T+ + L G SY FRV +E
Sbjct: 15664 TLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAE 15723
Query: 344 NLCGLSTSATVTKELAHIQKADIAAKPKGFI 374
N G+ A E A KA P G I
Sbjct: 15724 NEYGIGLPA----ETAESVKASERPLPPGKI 15750
Score = 144 bits (362), Expect = 2e-34
Identities = 86/282 (30%), Positives = 140/282 (49%), Gaps = 4/282 (1%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P L + +V+ ++VT++W PP+ G + YVLE G ++ V+ ++ +
Sbjct: 10411 VPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 10470
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV+ L GD + RVSAV+ G G P+ +PI ++ + P + + R +VG
Sbjct: 10471 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL--DFRDKLTIRVG 10528
Query: 190 ETVNLQIPFQGKPKPQATW-THNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
E L + GKPKP+ +W L+ R ++T L A+RSDSG+Y + V
Sbjct: 10529 EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV 10588
Query: 249 RVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
K + V+++PGPP + +V + W PP D G +++ Y+++K +
Sbjct: 10589 ENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKE 10648
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
W V TTC +S L+ G Y FR+ +ENL G+S
Sbjct: 10649 VGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGIS 10690
Score = 144 bits (362), Expect = 2e-34
Identities = 84/305 (27%), Positives = 146/305 (47%), Gaps = 10/305 (3%)
Query: 54 APTASTATKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A A + KP+ PS+ + P P + D + +SV+++W PE G + GY
Sbjct: 23703 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 23762
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165
++E+ + EW + P + + T+ +L G ++ RV A ++ G G PA + + +
Sbjct: 23763 LIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23822
Query: 166 RENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG 225
E +E P + ++ + G + L IP +GKP P WT G + S+R + T
Sbjct: 23823 TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI-SKRAMIATS 23881
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
+ + L I+ A R DSG Y+L + + + I + VI P P + D+ +
Sbjct: 23882 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR 23941
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
+ W PP D G ++LGY++++ + W+T+ R T+ + L Y FRV +EN
Sbjct: 23942 VSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 24001
Query: 345 LCGLS 349
G+S
Sbjct: 24002 QFGIS 24006
Score = 140 bits (354), Expect = 2e-33
Identities = 81/280 (28%), Positives = 142/280 (50%), Gaps = 2/280 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P + D +++S+ ++W+PP+ G ++GY++E C G+ +WV P+ T+
Sbjct: 7282 VPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETK 7340
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
V L G + RV A++ GA P+ + I + EAP+I + L + G
Sbjct: 7341 MEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAG 7400
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
+ L GKP+P+ TWT L +R+++ + S + I ++RSD+G Y +
Sbjct: 7401 TKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEA 7460
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
A AV+++ V++KPGPP++ + DV + L W PP+D G +++ Y+V++
Sbjct: 7461 VNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRAT 7520
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ W + T + LI Y FRV +EN+ G+
Sbjct: 7521 DSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGV 7560
Score = 140 bits (354), Expect = 2e-33
Identities = 91/313 (29%), Positives = 146/313 (46%), Gaps = 9/313 (2%)
Query: 54 APTASTATKPAPPSEDV-------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYV 106
A A+ K +PPS+ P P + + D SS+++ + WEPP G + GY
Sbjct: 8673 AENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYF 8732
Query: 107 LELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR 166
++ G +EW + + + V Q TV+ + G + LRVSAV++AG GPP QP+ +
Sbjct: 8733 VDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVA 8791
Query: 167 ENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGD 226
E E P + + ++ G+T+ + G+P P WT LD RV +
Sbjct: 8792 EPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVG 8851
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
S L I+ A R D GRY +T A + V + PGP ++ + L
Sbjct: 8852 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8911
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W+ P+D G +E+ G+++++ D K W +E + C I+ L+ G Y FRV ++N
Sbjct: 8912 WSDPEDDGGSEITGFIIERKDAKMHTWRQPIET-ERSKCDITGLLEGQEYKFRVIAKNKF 8970
Query: 347 GLSTSATVTKELA 359
G + LA
Sbjct: 8971 GCGPPVEIGPILA 8983
Score = 140 bits (353), Expect = 3e-33
Identities = 88/305 (28%), Positives = 147/305 (48%), Gaps = 7/305 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
TK + PS P L + +S SV+++W PE G + YV+E +G WV
Sbjct: 20060 TKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC 20119
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ T V L ++ RV A + AG P L P+ I+E +E P+I +
Sbjct: 20120 AVAKS--THHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFP 20177
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRS 239
T + G + + IP GKP P+ T + +G L + R + ++ + ++ + +
Sbjct: 20178 SHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA 20237
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+GRYE+T KA I+I+V+++PGPP+ + + D+ + L+W PP+ G +++
Sbjct: 20238 DAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQV 20297
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y++ K + T W V T + L G Y FR+ +EN G+S SA VT
Sbjct: 20298 TNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVT 20357
Query: 356 KELAH 360
+L +
Sbjct: 20358 VKLPY 20362
Score = 139 bits (351), Expect = 4e-33
Identities = 86/300 (28%), Positives = 149/300 (49%), Gaps = 6/300 (2%)
Query: 61 TKPAPPSED---VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEW 117
T P +ED +PS P + D +++T++W P G + GY +E + ++W
Sbjct: 19766 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 19825
Query: 118 VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVP 177
S + + T+ T+ L G +++ RV +V+ GA P+ P +E E P +
Sbjct: 19826 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 19884
Query: 178 RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQ 237
+R+T I + G + + +PF+G+P P W+ L + R + T D + L I +A
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENAN 19943
Query: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
R+DSG+Y LT++ A + + V++ PGPP++I + DV +A L W P++ G
Sbjct: 19944 RNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAP 20003
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
+ Y ++K + W +V + + +++L G Y FRV EN G+ A TKE
Sbjct: 20004 VKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKE 20062
Score = 138 bits (347), Expect = 1e-32
Identities = 87/299 (29%), Positives = 144/299 (48%), Gaps = 14/299 (4%)
Query: 61 TKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+ PSE D P P+ L +++ +VT+ W PE G + Y++E
Sbjct: 15037 SKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDL 15093
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEA 171
W+ + ++ + TV L + RV A ++AGA PP+ I R+++EA
Sbjct: 15094 PNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEA 15153
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSI 230
PKI+V + T I + GE L+ G+P P W+ +G L+ + ++ ++ D +
Sbjct: 15154 PKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN 15213
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTP 289
L + + R DSG Y LT AK + ++ V+++PGPP + + +V L W P
Sbjct: 15214 LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15273
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P D G ++ Y+VQK + W V T ++ L+ GN Y FRV + N G+
Sbjct: 15274 PLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15332
Score = 138 bits (347), Expect = 1e-32
Identities = 86/314 (27%), Positives = 145/314 (46%), Gaps = 10/314 (3%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V +P P+ P PPS + D S SSV+++W P G ++
Sbjct: 18679 VGEPSEPSVFYRACDALYPPGPPSNP--------KVTDTSRSSVSLAWSKPIYDGGAPVK 18730
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
GYV+E+ A EW + + +Q TV L ++ R+ A++S G G PA L
Sbjct: 18731 GYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 18790
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM 222
+ +E IE P+I + LR+ + + T+ L + +G+P+P+ W + + R +
Sbjct: 18791 VVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKW-EKAEGILTDRAQI 18849
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
++L I + R DSGRY LT+ A +++ V++ P P ++ + +V +
Sbjct: 18850 EVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDS 18909
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP G ++ Y+V+K + + T+ TT I +L G SY FRV +
Sbjct: 18910 VTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 18969
Query: 343 ENLCGLSTSATVTK 356
N G+ A T+
Sbjct: 18970 SNEYGIGLPAETTE 18983
Score = 137 bits (344), Expect = 3e-32
Identities = 85/320 (26%), Positives = 153/320 (47%), Gaps = 10/320 (3%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P + S K A PS P + D + S +++W P G L + GYV+E +
Sbjct: 14352 PSEASDSVLMKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 14408
Query: 112 EGASEWVP-VSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G W+ + + +TQ V +L +K+ R+SA++ AG G PA++ + I E
Sbjct: 14409 VGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREM 14467
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
AP + LR+T + + G ++ + +P +G+P P+ TWT + L + R ++ + ++
Sbjct: 14468 APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN-RANIENTESFTL 14526
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I R D+G++ +T+ + +++ V++ PGP ++R D+ + L W P
Sbjct: 14527 LIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLP 14586
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
G + + Y+V+K + + T + H T ++ L G Y FRV +EN G+
Sbjct: 14587 LIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14646
Query: 351 SATVTKELAHIQKADIAAKP 370
T+ + KA A P
Sbjct: 14647 PTETTEPV----KASEAPSP 14662
Score = 135 bits (340), Expect = 8e-32
Identities = 87/319 (27%), Positives = 146/319 (45%), Gaps = 11/319 (3%)
Query: 63 PAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P+PPS+ V PS P+ D + +SV ++W+PP G + GY++E + G
Sbjct: 10792 PSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGD 10851
Query: 115 SEWVPVSARPMMV--TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
EW + P T+ V L G + RV AV++AG PA + +P+ +++ +E P
Sbjct: 10852 EEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPP 10911
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
++ + ++ + +VG+T+ L +G P P+ TW + + + S L
Sbjct: 10912 ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT-KARIDVTPVGSKLE 10970
Query: 233 IRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
IR+A D G Y LTV + +LV++KPGPP + + ++ + L W P D
Sbjct: 10971 IRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLD 11030
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
G + + Y+V++ D + QW + + L GN Y FRV +EN G
Sbjct: 11031 DGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFV 11090
Query: 353 TVTKELAHIQKADIAAKPK 371
K + + PK
Sbjct: 11091 ETPKPIKALDPLHPPGPPK 11109
Score = 135 bits (340), Expect = 8e-32
Identities = 83/299 (27%), Positives = 153/299 (51%), Gaps = 2/299 (0%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ++ A + P P + D + SSV++SW P G + GY++E+ R
Sbjct: 13265 PGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKR 13324
Query: 112 EGASEWVPVSA-RPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
+ WV + + + T+ V L ++ RV AV+ G P+ + + ++ +
Sbjct: 13325 ADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 13384
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRTGDQDS 229
P+ + LR+T I + G T+ L +P +G+P P+ TW+ N + D + +++ D D+
Sbjct: 13385 PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDT 13444
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L + + D+G+Y LT+ + + I + V++ PGPP ++ + ++ +A + W P
Sbjct: 13445 FLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEP 13504
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P G + ++ Y+VQK D + W TV T+ +++L G SY FRVF+EN G+
Sbjct: 13505 PIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGI 13563
Score = 134 bits (338), Expect = 1e-31
Identities = 85/299 (28%), Positives = 151/299 (50%), Gaps = 10/299 (3%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P PT + + P P PS PL L + D + ++W+PPE+ G + GY +E+C
Sbjct: 7964 PSEPTEILSIEDPTSP----PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMC 8019
Query: 111 REGASEWVPVSARPMMVTQQTVRNLALGDK-FLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
G +W+ V++RP+ + V + DK ++LRV AV++ G P+ + + + ++
Sbjct: 8020 PVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPD 8079
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQD 228
P I + H I GE +++ +PF+ P P +W +G + S R++M+
Sbjct: 8080 CKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS 8136
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+ L + + R+D+G Y +T+ + A A I++ VI PGP I+ D+ + L W
Sbjct: 8137 AHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWE 8196
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G T +L Y++++ + + V+ + + T+ DLI Y FRV + N G
Sbjct: 8197 PPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8255
Score = 134 bits (338), Expect = 1e-31
Identities = 86/307 (28%), Positives = 140/307 (45%), Gaps = 11/307 (3%)
Query: 46 KPQAPAPQAPTAS-TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQG 104
K + P PT TA P P P P ++ DV+ S+V++ W P+ G + G
Sbjct: 12866 KAGSSPPSKPTEYVTARMPVDP----PGKPEVI---DVTKSTVSLIWARPKHDGGSKIIG 12918
Query: 105 YVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK--FLLRVSAVSSAGAGPPAMLDQP 162
Y +E C+ +WV + P + Q+ L +K + R A ++ PP+ P
Sbjct: 12919 YFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12978
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVS 221
+ I P+I + ++ + G V L GKP P +W +G L ++ +
Sbjct: 12979 VTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK 13038
Query: 222 MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGC 281
M L + S R DSG Y +T A I + V++KPGPP+S+++ ++
Sbjct: 13039 MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSD 13098
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
A L W PP + G +E+ Y+V K + W V T+C++ LI G+ Y FR+
Sbjct: 13099 RAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRIC 13158
Query: 342 SENLCGL 348
+EN G+
Sbjct: 13159 AENKYGV 13165
Score = 134 bits (337), Expect = 2e-31
Identities = 111/426 (26%), Positives = 182/426 (42%), Gaps = 23/426 (5%)
Query: 48 QAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVL 107
+ P + P A P P P P L DV + V++ W P+R G + GY++
Sbjct: 11086 RGPFVETPKPIKALDPLHP----PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11141
Query: 108 ELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E EG +W+ + + + V L G + RV A + G G P PI +E
Sbjct: 11142 EYQEEGTQDWIKF--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 11198
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSMRTGD 226
+ P + + L + + + G TV +G P P A WT +G + + + ++ T +
Sbjct: 11199 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11258
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
S+L I++ R D+G Y++TV + + V++ PGPP+ I +LDV + +
Sbjct: 11259 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11318
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W PP+D G + ++ Y+V+K D + W V T I L G Y FRV +EN
Sbjct: 11319 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 11378
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE---APSFTQPLADHTS-TPGY---- 397
G+ T +A K + P + D +E S+T P +D S GY
Sbjct: 11379 IGVGPPLDSTPTVAK-HKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 11437
Query: 398 --STQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
T + V +P + + + ++R +E + KPSP + C+
Sbjct: 11438 REVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 11494
Query: 456 AINVLG 461
I G
Sbjct: 11495 PIKPPG 11500
Score = 133 bits (335), Expect = 3e-31
Identities = 99/424 (23%), Positives = 187/424 (44%), Gaps = 20/424 (4%)
Query: 41 EEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRL 100
E +V A P+ +T A P P + D + +S+T++W P G
Sbjct: 17585 EFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGS 17644
Query: 101 GLQGYVLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAML 159
+ GYV+E+C+ EW V+ + + VT+ + L ++ +RV A++ G G +
Sbjct: 17645 EILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV 17704
Query: 160 DQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
+ + +EAP++ + LR+ + + G + + IPF+G+P P+ TW+ + +
Sbjct: 17705 PGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDK 17763
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
V + G + L I + R+D+G+Y L + A + + V++ PGPP ++ + +V
Sbjct: 17764 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17823
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR 339
+A L W PP G ++ Y++ K + + V + T+ + +L G Y FR
Sbjct: 17824 KDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFR 17883
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
V +EN G+ V E KA P G + L D + T ++
Sbjct: 17884 VMAENEFGVG----VPVETVDAVKAAEPPSPPGKV------------TLTDVSQTS--AS 17925
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
++ +++ +M+ +G K+ ++E VC + S + KA N
Sbjct: 17926 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNE 17985
Query: 460 LGEA 463
G++
Sbjct: 17986 KGKS 17989
Score = 132 bits (332), Expect = 7e-31
Identities = 74/289 (25%), Positives = 139/289 (48%), Gaps = 11/289 (3%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT-- 128
P P + D + SS+++ W+PP + G ++GY++E+ EG ++W V+ ++T
Sbjct: 9400 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9459
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ V NL K+ RV AV+ AG P+ I + E P++ + + + +
Sbjct: 9460 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9519
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR---------VSMRTGDQDSILFIRSAQRS 239
G + + +G+P P+++W +G A + + + T + S++ I +RS
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
+G+Y +T + + + A + V++ PGPP +++ D+ + L W P D G +
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIK 9639
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
GY+++K W V TT + DL+ Y FRV +EN G+
Sbjct: 9640 GYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 9688
Score = 132 bits (332), Expect = 7e-31
Identities = 84/317 (26%), Positives = 143/317 (45%), Gaps = 3/317 (0%)
Query: 57 ASTATKPAPPSEDV-PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
AS + PA + + P P + D + SS + W PP + G + GY++E EG
Sbjct: 10101 ASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKE 10160
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIR 175
EW + + T+ V L G + RV AV+ AG G P + I +++ + +P ++
Sbjct: 10161 EWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQ 10220
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRS 235
+ +R + G + + GKP P TW N L Q ++ T S + I++
Sbjct: 10221 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL-PQEATIETTAISSSMVIKN 10279
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTG 294
QRS G Y L + E E K I + V++ PGP + L ++ + L W P+D G
Sbjct: 10280 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 10339
Query: 295 NTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATV 354
+ + Y+++K + W V T+ LI G +Y FR+ +EN G+
Sbjct: 10340 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 10399
Query: 355 TKELAHIQKADIAAKPK 371
++ L + + +P+
Sbjct: 10400 SEALVIREPITVPERPE 10416
Score = 131 bits (329), Expect = 2e-30
Identities = 90/314 (28%), Positives = 138/314 (43%), Gaps = 14/314 (4%)
Query: 52 PQAPTASTATKPAPPSEDV--PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P PT KP S+ + P P L + +++ +S T++W PP R G + GY+
Sbjct: 12475 PGVPT--DVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSY 12532
Query: 110 CREG--ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E A W S + V L G K+ RV+A ++ G P + +E
Sbjct: 12533 REEEQPADRWTEYSV--VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE 12590
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHN-GHALDSQRVSMRTGD 226
+ PKI +P + + G+ + ++ GKP P W + S +++ D
Sbjct: 12591 QLLPPKILMPEQITI----KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 12646
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
SIL I+ R DSG Y LT I ++V++ PGPP + D+ +L
Sbjct: 12647 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 12706
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W P + G + + Y+V+K D G W T L T+C + LI G Y FRV +EN
Sbjct: 12707 SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12766
Query: 346 CGLSTSATVTKELA 359
G+S T K +A
Sbjct: 12767 FGISEPLTSPKMVA 12780
Score = 131 bits (329), Expect = 2e-30
Identities = 83/309 (26%), Positives = 147/309 (47%), Gaps = 12/309 (3%)
Query: 46 KPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
+P P+ KP PP+ P ++ D++ SSV +SW P G +QGY
Sbjct: 16516 EPSPPSAYQKACDPIYKPGPPNN-----PKVI---DITRSSVFLSWSKPIYDGGCEIQGY 16567
Query: 106 VLELCREGASEWVPVS-ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E C EW + + T V L ++ R+ A++ AG G A + PI
Sbjct: 16568 IVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPII 16627
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMR 223
+ E +EAP I + LR+ + G ++ L +P +G+P P+ W +G D+ + +
Sbjct: 16628 VEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT 16687
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ + L + + R DSG+Y LT+ A + + V++ P PP ++++ ++ +
Sbjct: 16688 S--SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16745
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
++ W PP G +++ Y+V+K + + V+ H + I L G SY FRV +E
Sbjct: 16746 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16805
Query: 344 NLCGLSTSA 352
N G+ A
Sbjct: 16806 NEYGIGLPA 16814
Score = 130 bits (326), Expect = 3e-30
Identities = 82/290 (28%), Positives = 144/290 (49%), Gaps = 7/290 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+ A + P + L + VS SS ++ W+ P G + GYV++ E ++W V
Sbjct: 13569 TRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKWQRV 13627
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ Q + ++L G ++ RVSA + G G P+ + + R+++ AP + +
Sbjct: 13628 MKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLP 13683
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRS 239
Y+ + L+IP +GKP P +W L + RVS+ + ++ L + Q+S
Sbjct: 13684 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13743
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G+Y +T++ + I I V+ KPG P+ I+ +V L+W PP+D G +E+
Sbjct: 13744 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13803
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Y+++K D +W T TT ++ L G Y+FRV +EN G+
Sbjct: 13804 TNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13853
Score = 129 bits (325), Expect = 4e-30
Identities = 91/314 (28%), Positives = 152/314 (48%), Gaps = 15/314 (4%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P P+ K P P P P + D + S+T+ W P G + GYV+E+
Sbjct: 12176 PSLPSRPVVAKDPIEP----PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMR 12231
Query: 111 REGASE-----WVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ A W +A +V ++ TV +L ++ RV A + G G PA L + I
Sbjct: 12232 PKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 12291
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
+E +E P+I + +R+ I + G + L +G+P P+ TW G ++ +
Sbjct: 12292 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL 12351
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
D + L I ++ R DSG+Y LT+ E +++ V++ PGP S +++ DV +
Sbjct: 12352 VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCH 12411
Query: 285 LQWTPPQDTGNTELLGYMVQK--ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
+ W PP++ G +++ Y+V+K AD+KT W TV T+ +++L+ GN Y FRV +
Sbjct: 12412 VSWAPPENDGGSQVTHYIVEKREADRKT--WSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12469
Query: 343 ENLCGLSTSATVTK 356
N G V K
Sbjct: 12470 VNEYGPGVPTDVPK 12483
Score = 124 bits (310), Expect = 2e-28
Identities = 79/279 (28%), Positives = 135/279 (48%), Gaps = 5/279 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR-PMMVTQ 129
PSAP ++ D + S++++W P G + GYVLE+ + +W V + T+
Sbjct: 23040 PSAPRVV---DTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 23096
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV +L +G K+ RV+AV+ G + I E IE P + + L++T + G
Sbjct: 23097 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAG 23156
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
++ L + G+P P TW+ G L S R + T + S+L + R D+G+Y +
Sbjct: 23157 ASLRLMVSVSGRPPPVITWSKQGIDLAS-RAIIDTTESYSLLIVDKVNRYDAGKYTIEAE 23215
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ + A + + V + PGP S+++ +V + + W P G + Y+V+K +
Sbjct: 23216 NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAA 23275
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ TV + T IS L+ G Y FRV EN+ G+
Sbjct: 23276 MRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23314
Score = 123 bits (309), Expect = 3e-28
Identities = 83/281 (29%), Positives = 129/281 (45%), Gaps = 4/281 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P+ P L + D S SS ++W P+ G + GY+LE+ ++G+ WV +
Sbjct: 22241 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTF-- 22298
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV L ++ RV A + AG P + I+E P + Q + G
Sbjct: 22299 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGS 22358
Query: 191 TVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ +P G+P P+ TW L ++ RVS+ T + L ++ + R DSGRY LT+
Sbjct: 22359 PFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLE 22418
Query: 250 VEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ ++VI +PGP + I + V + L W P+D G TE+ Y+V+K +
Sbjct: 22419 NTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRES 22478
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
T W V T ++ L YSFRV SEN G+S
Sbjct: 22479 GTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVS 22519
Score = 123 bits (308), Expect = 4e-28
Identities = 90/304 (29%), Positives = 137/304 (45%), Gaps = 10/304 (3%)
Query: 54 APTASTATKPAPPSE-----DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A+ KP+ PSE D P + + D+S +SV++SW+ P G + GY++E
Sbjct: 20441 AENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE 20500
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRE 167
W S + TQ + L ++ RV A ++ G+ P+ + PI +
Sbjct: 20501 RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCID 20560
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM--RTG 225
+ P I +P + + G +V L+ GKP P W + L + + T
Sbjct: 20561 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTT 20620
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
D SIL I+ A R +SG YEL +R A A I + +++KPGPP I V
Sbjct: 20621 DLASIL-IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKIT 20679
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L W PP D G ++ Y+V+K + W V E T + +I GN Y FRV + N
Sbjct: 20680 LLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVN 20739
Query: 345 LCGL 348
G+
Sbjct: 20740 KYGI 20743
Score = 122 bits (307), Expect = 5e-28
Identities = 110/421 (26%), Positives = 172/421 (40%), Gaps = 35/421 (8%)
Query: 67 SEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMM 126
S + P PL DD+ SV VSW PP G + GY+LE + W + +R +
Sbjct: 23922 SPNSPEGPL--EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VR 23978
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK--IRVPRHLRQT- 183
T V+ L ++ RVSA + G P ++P+ + + P+ P L T
Sbjct: 23979 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTK 24038
Query: 184 ------YIRQVGETVNLQIPFQGKPKPQAT--WT-HNGHALDSQRVSMRTGDQDSILFIR 234
+ R + + + + K +T W HN + + ++ D+ R
Sbjct: 24039 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 24098
Query: 235 SAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++D G E + E + K D KP P + +L + + LQW P+ G
Sbjct: 24099 IIAQNDVGLSETSPASEPVVCKDPFD-----KPSQPGELEILSISKDSVTLQWEKPECDG 24153
Query: 295 NTELLGYMVQKADKKTGQWF-TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
E+LGY V+ W + ER TI L+ Y FRVF+EN GLS
Sbjct: 24154 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24213
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKI 413
+ K + + EAP + + D T+ G + QL C + P P I
Sbjct: 24214 TAMSI----KTKLTS----------GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 24259
Query: 414 IWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
W + E+ + KY+ S+ TL + D GVYTC A N +GE +L ++A
Sbjct: 24260 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24319
Query: 474 S 474
+
Sbjct: 24320 T 24320
Score = 120 bits (300), Expect = 4e-27
Identities = 72/270 (26%), Positives = 126/270 (46%), Gaps = 3/270 (1%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V + +T+ W P G + GY++E W+ S ++ TQ TV L ++
Sbjct: 17227 VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRY 17286
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AGA P+ PI ++ +E P+I + R T + GET L+ G
Sbjct: 17287 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 17346
Query: 201 KPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W ++ S R ++ D ++L ++ A R D G+Y L +
Sbjct: 17347 KPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPV 17406
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP +++ V +L W+PP G +++ Y+V+K + W V
Sbjct: 17407 NVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVAS 17466
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ ++ L+ GN Y FR+ + N G+
Sbjct: 17467 EVVTNSLKVTKLLEGNEYVFRIMAVNKYGV 17496
Score = 117 bits (293), Expect = 2e-26
Identities = 77/312 (24%), Positives = 140/312 (44%), Gaps = 13/312 (4%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V+ +SVT+ W+ P G + GY++E W+ S ++ T V L ++
Sbjct: 16145 VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 16204
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AG P+ I R+ ++ P+I + + T + GE+ + G
Sbjct: 16205 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16264
Query: 201 KPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W L ++ R+ +++ D + L ++ A R DSG Y L + E +
Sbjct: 16265 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16324
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP + + V L W PP G ++++ Y+V++ + W V
Sbjct: 16325 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 16384
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
+C ++ L+ GN Y+FR+ + N G+ ++ + AK F+ D
Sbjct: 16385 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP---------LESEPVVAK-NPFVVPDA 16434
Query: 379 SEAPSFTQPLAD 390
+AP T D
Sbjct: 16435 PKAPEVTTVTKD 16446
Score = 116 bits (291), Expect = 4e-26
Identities = 77/322 (23%), Positives = 147/322 (45%), Gaps = 13/322 (4%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+P S+ + P P+ L D S + + W P G + GYV+E +
Sbjct: 11481 SKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKP 11540
Query: 113 GASEWVPVSARPMMVTQQTVR--NLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G ++W ++ + ++ Q R L G+++ R+ A + G G P L + + ++ +
Sbjct: 11541 GTAQWNRIN-KDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILH 11599
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
P++ + R +VG+T+ + +G+P+P TWT G L +RV +
Sbjct: 11600 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV 11659
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L I+ A R+D G+Y ++ + A+ + V+++PGP ++++ +V N + W
Sbjct: 11660 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWEN 11719
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
P D G +E+ ++V+ W V ++L+ N Y FRV +EN G+
Sbjct: 11720 PLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGVG 11778
Query: 350 TSATVTKELAHIQKADIAAKPK 371
+ + I D +P+
Sbjct: 11779 PTIETKTPILAINPIDRPGEPE 11800
Score = 116 bits (290), Expect = 5e-26
Identities = 83/297 (27%), Positives = 140/297 (47%), Gaps = 14/297 (4%)
Query: 62 KPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
KP+ PSE D P P ++ +++ +SVT+ W P+ G L GY++E
Sbjct: 13955 KPSLPSEPVVALDPIDPPGKPEVI---NITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLP 14011
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAP 172
+ W+ + + TV +L G K+ R+ A ++AGA P+ + I ++ EAP
Sbjct: 14012 SKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14071
Query: 173 KIRVPRHLRQTYIRQVGETVNLQ-IPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSI 230
I + ++ + G+T+ L I GKP P+++W+ G + ++ T S+
Sbjct: 14072 TIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 14131
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I+ A R D+G Y +T + + V++ PGPP + + +V A L WTPP
Sbjct: 14132 LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP 14191
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
+ G + + Y+++K + W V E + LI GN Y FRV + N G
Sbjct: 14192 LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14248
Score = 115 bits (288), Expect = 9e-26
Identities = 75/309 (24%), Positives = 133/309 (43%), Gaps = 36/309 (11%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P+ + + + ++ ++T++W+PP G + GY++E +G W + + +
Sbjct: 8275 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8334
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T + L G ++ RV A ++AG P+ P + I+APK+ LR + + G+
Sbjct: 8335 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSLEVKRGD 8390
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG------------------------- 225
+ L G P P TW + + + + + R
Sbjct: 8391 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 8450
Query: 226 -----DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWG 280
+S L +R + R D G Y + V + AKA + V++ PGPP + D+
Sbjct: 8451 IDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRK 8510
Query: 281 CNAALQWTPPQDTGNTELLGYMVQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSF 338
+ +W PP D G +E++ Y ++K D K +W V +++ LI G Y F
Sbjct: 8511 TSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLF 8570
Query: 339 RVFSENLCG 347
RV +EN G
Sbjct: 8571 RVRAENRFG 8579
Score = 115 bits (287), Expect = 1e-25
Identities = 87/321 (27%), Positives = 145/321 (45%), Gaps = 17/321 (5%)
Query: 54 APTASTATKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A ++ + P+ PS+ D P P + DV+ ++T+ W PP R G + GY
Sbjct: 21528 AENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGY 21584
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIH 164
+E R+G WV + + Q TV L+ GD++ R+ A ++ G PP+ I
Sbjct: 21585 SIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIM 21643
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
R+ P + I + GE++ ++ QG+P P+ TW +G ++ +R++M
Sbjct: 21644 TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNMEI 21702
Query: 225 GDQ--DSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGC 281
D + LF+R A R G Y + + AKA I + V + PG IR ++ G
Sbjct: 21703 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 21762
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
L W P + G + Y+++K + W + ++ + T LI GN Y FRV
Sbjct: 21763 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 21822
Query: 342 SENLCGLSTSATVTKELAHIQ 362
+ N G+ +A IQ
Sbjct: 21823 AVNKFGVGRPLDSDPVVAQIQ 21843
Score = 114 bits (284), Expect = 3e-25
Identities = 81/305 (26%), Positives = 136/305 (44%), Gaps = 7/305 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L + D + V + W P+ G Y +E +G+ +W V + T
Sbjct: 11794 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11853
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V + RV + G ++ + ++E+++ P + + L +
Sbjct: 11854 HYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVV-VKEDLQKPVLDLK--LSGVLTVKA 11910
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD---SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
G+T+ L+ +GKP P+ WT + A D S RV + T S + A+RSD G+Y
Sbjct: 11911 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11970
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
+T A + V++KPGP +++++DV + W PP+D G E+ Y+++K
Sbjct: 11971 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEK 12030
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ K W T T++ LI GN Y FRV +EN G + T +K + K D
Sbjct: 12031 CETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG-TGPPTESKPVIAKTKYD 12089
Query: 366 IAAKP 370
+P
Sbjct: 12090 KPGRP 12094
Score = 114 bits (284), Expect = 3e-25
Identities = 73/298 (24%), Positives = 141/298 (47%), Gaps = 12/298 (4%)
Query: 58 STATKPAPPSE--DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
S + +P P + D P P + +++ SV++ W P G + GY++E
Sbjct: 19368 SKSCEPVPARDPCDPPGQP---EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDG 19424
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKI 174
W+ + + T V L ++ RV A ++A + P+ PI +++++E P++
Sbjct: 19425 RWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRV 19484
Query: 175 RVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFI 233
+ R + + GE + + G+P P +W +G ++ + R + + D ++L +
Sbjct: 19485 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19544
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA---ALQWTPP 290
+ R D+G+Y LT++ ++ V++KPGPP+ L++ G A +L W P
Sbjct: 19545 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGP--LEINGLTAEKCSLSWGRP 19602
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Q+ G ++ Y+V+K + W T+C ++ L+ GN Y FRV N G+
Sbjct: 19603 QEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 19660
Score = 112 bits (279), Expect = 1e-24
Identities = 72/284 (25%), Positives = 129/284 (45%), Gaps = 7/284 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ ++VT+ W+ P G + GY++E W+ S ++ T
Sbjct: 18299 DPPGRPEAIV---ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLET 18355
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L ++ RV A ++AG P+ I R+ I+AP + + +
Sbjct: 18356 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18415
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALD--SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
GET L+ +GKP P W+ +G L+ + R+ +++ Q + L ++ R+D G+Y
Sbjct: 18416 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L + I + V+++PGPP +++ V L W PP G + Y+++
Sbjct: 18476 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 18535
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
K + W V ++ L+ GN Y FRV + N G+
Sbjct: 18536 KRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18579
Score = 107 bits (267), Expect = 2e-23
Identities = 103/376 (27%), Positives = 164/376 (43%), Gaps = 17/376 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P +E VP+ L++ D + +SV +SW P+ G + YV+E R+G E
Sbjct: 21149 TEPVKAAE-VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE--RKGKGEQTWS 21205
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
A + V L RV A + G P + PI ++E I P++ +
Sbjct: 21206 HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIP 21264
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++G V+L++P++GKPKP +W +G L +S+ V + L I++A++
Sbjct: 21265 GAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKE 21324
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS----IRLLDVWGCNAALQWTPPQDTGN 295
G+Y TV +++ + + I VI GPPS IR ++ + L W P+D G
Sbjct: 21325 HGGKY--TVILDNAVCRIAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21381
Query: 296 TELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
E+ Y ++K + W V TT + +L+ Y FRV +EN G+S +
Sbjct: 21382 GEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSS 21441
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+A Q K I S+ S T D G S V + I+W
Sbjct: 21442 IIVAKHQFRIPGPPGKPVIYNVTSDGMSLTW---DAPVYDGGSEVTGFHVEKKERNSILW 21498
Query: 416 MK-NKMEIQGNPKYRA 430
K N I G +YRA
Sbjct: 21499 QKVNTSPISGR-EYRA 21513
Score = 107 bits (266), Expect = 3e-23
Identities = 88/337 (26%), Positives = 145/337 (43%), Gaps = 14/337 (4%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P++P LT + + S++T+ W+ P G +QGY++E R ++ V+ R T
Sbjct: 8990 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 9049
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVG 189
V NL + RV AV+ G P+ L + I+++ P I++ +R I+ + G
Sbjct: 9050 LVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAG 9108
Query: 190 ETVNLQIPFQGKPKPQATWTHN-------GHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
E V++ G P P+ W+ N AL + + + + L I A R D G
Sbjct: 9109 EPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKG 9168
Query: 243 RYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYM 302
Y +T + + V ++P PP ++ + D+ + L W P D G +E+ Y+
Sbjct: 9169 TYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 9228
Query: 303 VQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAH 360
+ K D +K +W V I LI Y FRV + N G+S K +
Sbjct: 9229 IDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 9288
Query: 361 --IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTP 395
+ KPK S S+T PL D+ +P
Sbjct: 9289 DPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSP 9324
Score = 107 bits (266), Expect = 3e-23
Identities = 81/313 (25%), Positives = 135/313 (43%), Gaps = 22/313 (7%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P + +TA P P P P+ L + ++ ++V +SW+PP+ G + Y++E
Sbjct: 9690 PPVETIQRTTARDPIYP----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC 9745
Query: 110 CREGAS-----EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ W + R + Q TV +L G ++ RV AV++AG P+ P
Sbjct: 9746 LAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCD 9805
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATW--------THNGHALD 216
+ P I L++ + G VN+ +G P P TW + L
Sbjct: 9806 CQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY 9861
Query: 217 SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRL 275
V+ D L I ++RSD+G Y +T A + + V+ +PGPP I+
Sbjct: 9862 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKF 9921
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
V L W PP+D G +++ Y+++K + W V T TI L+ G+
Sbjct: 9922 ESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHE 9981
Query: 336 YSFRVFSENLCGL 348
Y FR+ ++N G+
Sbjct: 9982 YVFRIMAQNKYGI 9994
Score = 105 bits (263), Expect = 7e-23
Identities = 89/333 (26%), Positives = 143/333 (42%), Gaps = 11/333 (3%)
Query: 23 KVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLD 80
KVP E +V E Q A AS A++P A D P P +
Sbjct: 22587 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP---EVT 22643
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLE---LCREGASEWVPVSARPMMVTQQTVRNLAL 137
DV+ S+V++ W P G + GY++E + G W+ + + TV L+
Sbjct: 22644 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 22703
Query: 138 GDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVGETVNLQ 195
GD + RV A ++AG + P+ R+ PK + L + + G + L
Sbjct: 22704 GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLD 22763
Query: 196 IPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLE 254
GKP+P+ WT LD ++VS++ + + I+ RSDSG+Y LTV+
Sbjct: 22764 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 22823
Query: 255 AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF 314
+ + V++ PGP + + V L W+ PQ+ G E+ Y+V++ + W
Sbjct: 22824 KAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV 22883
Query: 315 TVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
V + ++ LI N Y FRV + N G
Sbjct: 22884 IVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG 22916
Score = 102 bits (254), Expect = 8e-22
Identities = 105/421 (24%), Positives = 177/421 (42%), Gaps = 43/421 (10%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P LT+ V+ T++W P+ G + Y++E WV V ++
Sbjct: 22834 DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS 22893
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
R L ++++ RV AV+ G G P +PI R + P P + + +V
Sbjct: 22894 YVVTR-LIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPS---PPGIPE----EV 22944
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQ--------RVSMRTGDQDSILFIRSAQRSD 240
G I KP+ + + +D + RV+ D+ L + S
Sbjct: 22945 GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGC 23004
Query: 241 SGRYELTV-----RVEDLEAKAVIDILVIE-KPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++ +T E EA I PGPPS+ R++D + +L WT P G
Sbjct: 23005 DYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDG 23064
Query: 295 NTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
T+++GY+++ +K T QW+ V T T+ DL +G YSFRV + N+ G+S +
Sbjct: 23065 GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYS 23124
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
E+ +++ +I D A + + T G S +L SV P P
Sbjct: 23125 ESIAEIEPVERIEIP---------DLELADDLKKTV---TIRAGASLRLMVSVSGRPPPV 23172
Query: 413 IIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
I W K +++ RA+ + + L + K + +D+G YT +A N G+ S ++
Sbjct: 23173 ITWSKQGIDLAS----RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23228
Query: 471 V 471
V
Sbjct: 23229 V 23229
Score = 100 bits (249), Expect = 3e-21
Identities = 105/423 (24%), Positives = 170/423 (40%), Gaps = 42/423 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DVSS TV W+PPE G +Q Y+LE C W SA ++
Sbjct: 11990 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSAT-VLTP 12048
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
TV L G++++ RV A + G GPP +P+ + + P P + T + +
Sbjct: 12049 GTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDKPGRPDPPEV--TKVSKE 12105
Query: 189 GETVNLQIP------------FQGKPKPQATWTH-NGHALDSQRVSMRTGDQDSILFIRS 235
TV P + K K W N A+ +R+ ++ ++L
Sbjct: 12106 EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQ-----NLLPDHE 12160
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
Q E+ + L ++ V+ IE PGPP++ R++D + L W P G
Sbjct: 12161 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGG 12220
Query: 296 TELLGYMVQK----ADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++GY+V+ AD + + + T++ L Y FRV ++N G+
Sbjct: 12221 APIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGI 12280
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
A + + A KPK +E + + + L G +LF VR
Sbjct: 12281 GRPAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGR 12328
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P PK+ W K ++ L + + L I + DSG Y+ +N GE +V
Sbjct: 12329 PAPKVTWRKVGIDNVVRKGQVDLVDT-MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12387
Query: 469 LEV 471
+ V
Sbjct: 12388 VRV 12390
Score = 100 bits (248), Expect = 4e-21
Identities = 80/321 (24%), Positives = 140/321 (43%), Gaps = 21/321 (6%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ST D P P T+ DV +SV ++W PE G ++ YV+E+ +
Sbjct: 7660 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLK 7719
Query: 112 EGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEA 171
G EWV V A + TQ + L G ++ RV AV+ AG P+ P+ RE +
Sbjct: 7720 TGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7778
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKP------------QATWTHNGHALDSQR 219
P PR L I + + +P + P + W + +
Sbjct: 7779 PS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTK 7836
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
++ + S+ R A + G+ + T +ED +V+ PGPP ++ ++DV
Sbjct: 7837 CTVTPLTEGSLYVFRVAAENAIGQSDYT-EIED----SVLAKDTFTTPGPPYALAVVDVT 7891
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSF 338
+ L+W PP++ G + Y+++K ++ +W + P ++D+I G F
Sbjct: 7892 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 7951
Query: 339 RVFSENLCGLSTSATVTKELA 359
+V +EN G+ + T+ L+
Sbjct: 7952 QVRAENEAGVGHPSEPTEILS 7972
Score = 97.1 bits (240), Expect = 3e-20
Identities = 80/302 (26%), Positives = 132/302 (43%), Gaps = 37/302 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L D++ +VT++W P+ G + GY +E +WV + P+ T
Sbjct: 7576 DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDT 7635
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V+ L K+ RV A + AG G P+ +PI I++ I+ P + ++ V
Sbjct: 7636 TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-----GKPTVKDV 7690
Query: 189 GETVNLQIPFQGKPKPQATWT---HNGHA-LDSQRVSM-RTGDQDSILFIRSAQRS---- 239
G+T + WT H+G A ++S + M +TG + + +
Sbjct: 7691 GKT-----------SVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLL 7739
Query: 240 ----DSGRYELTVRV-----EDLEAKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQW 287
+ Y VR E ++ +L EK P PP + ++++ A L+W
Sbjct: 7740 PGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKW 7799
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
T P+ G + + Y+V+K D + W TV T CT++ L G+ Y FRV +EN G
Sbjct: 7800 TVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIG 7859
Query: 348 LS 349
S
Sbjct: 7860 QS 7861
Score = 96.7 bits (239), Expect = 4e-20
Identities = 97/445 (21%), Positives = 172/445 (38%), Gaps = 86/445 (19%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP+ V + D++ SVT+ WEPP+ G + Y+L + W VS
Sbjct: 20264 RPGPPTGPV-------VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS 20316
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A + T V L G+++ R+ A + G I ++I++
Sbjct: 20317 AT-VARTMMKVMKLTTGEEYQFRIKAENRFG------------ISDHIDSA--------- 20354
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHN-----------------GHALDSQRVSMRT 224
V +++P+ P W N G A+ + M+
Sbjct: 20355 ---------CVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMK- 20404
Query: 225 GDQDSILFIRSAQR------------SDSGRYELTVRVEDLEAKAVID-----ILVIEKP 267
D++SIL+ ++ + S YE V E+ +L I+
Sbjct: 20405 -DRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC 20463
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCT 326
PP ++R+ D+ + +L W P G +++ GY+V++ D G+W T
Sbjct: 20464 EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFI 20523
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
IS L + Y FRVF+ N G + + ++ + I D P + +++E +
Sbjct: 20524 ISGLTQNSQYEFRVFARNAVG--SISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRA 20581
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
G S +L + P P I W K+ E+Q N + + ++ I+
Sbjct: 20582 ---------GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADR 20632
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
+SG Y K N +G AS R+++
Sbjct: 20633 LNSGCYELKLRNAMGSASATIRVQI 20657
Score = 96.3 bits (238), Expect = 5e-20
Identities = 95/412 (23%), Positives = 163/412 (39%), Gaps = 42/412 (10%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D+P P + D+VSS VT SW+PPE G + + YV+E+ + ++ WV ++ +
Sbjct: 14852 DIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRT 14911
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPA-----MLDQPIHIRENIEAPKIRVPRHLRQ 182
T + R L G ++ RV A + G GP + + P + P++
Sbjct: 14912 TYKATR-LTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQV-------- 14962
Query: 183 TYIRQVGETVNLQIPFQGKPKPQATW-----THNGHALDSQRVSMRTGDQDSILFIRSAQ 237
T + + T++ P P + NG + ++ G+ +S+
Sbjct: 14963 TAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGN-----IFKSSG 15017
Query: 238 RSDSGRYELTVRVEDLEAKAVID-----ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+D YE V E++ K+ +L ++ PP L++ L+W P+
Sbjct: 15018 LTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEY 15077
Query: 293 TGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
TG ++ Y+V+K D G+W T+S L +Y FRV ++N G +
Sbjct: 15078 TGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISP 15137
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ + I D PK ++ F + G + +L V P P
Sbjct: 15138 PSEPSDA--ITCRDDVEAPKIKVDVKFKDTVILKA---------GEAFRLEADVSGRPPP 15186
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ W K+ E++G K L + + DSG YT A N G A
Sbjct: 15187 TMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 15238
Score = 94.4 bits (233), Expect = 2e-19
Identities = 96/427 (22%), Positives = 163/427 (38%), Gaps = 50/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ V +D+V++ S+T+SW PP+ G + Y++E + W VS
Sbjct: 15935 KPGPPTGPVK-------MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15987
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGP-----PAMLDQPIHIRENIEAPKIRV 176
A T + R L G ++ R++A + G P + P + P + +
Sbjct: 15988 ATVARTTIKACR-LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 16046
Query: 177 PRHLRQTYIRQVGETVN------LQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
R + Q E ++ + + K + W Q TG ++ +
Sbjct: 16047 SS--RDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16104
Query: 231 LFIRSAQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAAL 285
YE V E++ + V + V P PP + V + L
Sbjct: 16105 ------------EYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTL 16152
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSEN 344
QW P G +++ GY+V+K + G+W T ++ L+ + Y FRV + N
Sbjct: 16153 QWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARN 16212
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G+ + + + I D P+ S P + + H G S ++
Sbjct: 16213 AAGVFSEPS--ESTGAITARDEVDPPR------ISMDPKYKDTIVVHA---GESFKVDAD 16261
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ P P I W+K E+ + S +L ++ DSG Y KA NV GE S
Sbjct: 16262 IYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERS 16321
Query: 465 VDCRLEV 471
V ++V
Sbjct: 16322 VTVNVKV 16328
Score = 90.5 bits (223), Expect = 3e-18
Identities = 95/411 (23%), Positives = 162/411 (39%), Gaps = 38/411 (9%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
DVP P + + DV+ +T+SW+PP+ G + Y++E W VS+
Sbjct: 11297 DVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK- 11355
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ + +L G +++ RV A + G GPP LD + ++ +P P T I +
Sbjct: 11356 TKLKIPHLQKGCEYVFRVRAENKIGVGPP--LDSTPTVAKHKFSPP-SPPGKPVVTDITE 11412
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
TV+ +P P + + + V + + F R + YE
Sbjct: 11413 NAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYEFR 11471
Query: 248 VRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
V E+L + + I+ PGPP + +L D A L WT P G + +L
Sbjct: 11472 VFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPIL 11531
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCT--ISDLIIGNSYSFRVFSENLCGLS-----TSA 352
GY+V+ T QW + + C + LI GN Y FR+ + N+ G +
Sbjct: 11532 GYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAES 11591
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
+ K++ H + ++ + I T G + ++ V+ P+P
Sbjct: 11592 VIAKDILHPPEVELDVTCRDVI-----------------TVRVGQTIRILARVKGRPEPD 11634
Query: 413 IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
I W K + + + + L+I++ D G Y A N G A
Sbjct: 11635 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 11685
Score = 87.4 bits (215), Expect = 3e-17
Identities = 96/411 (23%), Positives = 161/411 (39%), Gaps = 48/411 (11%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
+++ +T+ W+ P G + Y++E W + + T L G++
Sbjct: 21758 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNE 21816
Query: 141 FLLRVSAVSSAGAGPPAMLDQPI-HIRENI-EAPKIRVPRHLRQTYIRQV-------GET 191
+ RVSAV+ G G P D + I+ + +AP I P ++ I G +
Sbjct: 21817 YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGS 21876
Query: 192 VNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVE 251
Q + + K W + S+R T + + L ++ YE V E
Sbjct: 21877 EIQQYILERREKKSTRWVK----VISKRPISETRFKVTGL-------TEGNEYEFHVMAE 21925
Query: 252 DLEA---KAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
+ + I L+ + PGPP+ +++ D +L+W+ P G E++GY++
Sbjct: 21926 NAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYII 21985
Query: 304 QKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ 362
+ G W V E T T++DL G Y FRV + N G S VT I+
Sbjct: 21986 EMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIK 22042
Query: 363 KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI 422
D P+ I+ +F + H G S +LF + + P P +W K
Sbjct: 22043 AVDRLTAPELDIDANFKQT---------HVVRAGASIRLFIAYQGRPTPTAVWSKP---- 22089
Query: 423 QGNPKYRA--LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
N RA + TL + + D+G YT N G S+ ++V
Sbjct: 22090 DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 22140
Score = 86.7 bits (213), Expect = 4e-17
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 4/180 (2%)
Query: 180 LRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQR 238
L++ Y VG T+ L + + G+P P TW H L +S+ +++ + + L +++ QR
Sbjct: 24329 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 24388
Query: 239 -SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA-LQWTPPQDTGNT 296
+ +G+Y++ + A++D+ + +KP P+ +++ N+A + W PP D G +
Sbjct: 24389 KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGS 24448
Query: 297 ELLGYMVQKADKKTG-QWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+ Y+V+K + K G +W V TTC I +L Y FRV ++N G+S V+
Sbjct: 24449 WITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVS 24508
Score = 86.3 bits (212), Expect = 6e-17
Identities = 51/201 (25%), Positives = 95/201 (47%), Gaps = 6/201 (2%)
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
APKI+ Q + VG+ + + +P+ PK +A W L ++ + T +Q S
Sbjct: 6694 APKIKTAD---QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSF 6749
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
+ A++ D GRY++ ++ + +A+ I++ VI+ PGP ++ + + + +L W P
Sbjct: 6750 RILE-AKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEP 6808
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGN-SYSFRVFSENLCGLS 349
G ++++GY+V++ D K W +R T++ L G Y FRV + N G
Sbjct: 6809 LTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTG 6868
Query: 350 TSATVTKELAHIQKADIAAKP 370
+ K D+ P
Sbjct: 6869 EPVETDNPVEARSKYDVPGPP 6889
Score = 86.3 bits (212), Expect = 6e-17
Identities = 96/417 (23%), Positives = 171/417 (41%), Gaps = 60/417 (14%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P+ P+ D+V++ ++T+ W PP+ G + Y+LE ++WV ++ T
Sbjct: 13773 IPTGPI--KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTF 13830
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
+ R L G ++ RVSA + G G + +PI R + P P ++ V
Sbjct: 13831 RVTR-LHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVS 13888
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR-YELTV 248
T PK G+ L+ + +++S+L+ R+ + R +++T
Sbjct: 13889 LTWT-------DPKKTGGSPITGYHLEFK-------ERNSLLWKRANKTPIRMRDFKVTG 13934
Query: 249 RVEDLEAK---AVIDILVIEKPG-------------PPSSIRLLDVWGCNAALQWTPPQD 292
E LE + I++ + KP PP ++++ + L WT P+
Sbjct: 13935 LTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKY 13994
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTS 351
G +L GY+V+K D + W P T++DL+ G Y FR+ ++N G ++
Sbjct: 13995 DGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISA 14054
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQL-------FCS 404
+ + E I +D EAP+ + D T G + + S
Sbjct: 14055 PSESTET--------------IICKDEYEAPTI---VLDPTIKDGLTIKAGDTIVLNAIS 14097
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P PK W K +I+ + + S L I+ + D+G YT A N G
Sbjct: 14098 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154
Score = 85.9 bits (211), Expect = 7e-17
Identities = 105/431 (24%), Positives = 166/431 (38%), Gaps = 52/431 (12%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T KP PP V DDVS+ S+T+SW PP G + Y+++ + W
Sbjct: 17014 TLDKPDPPKGPVK-------FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWD 17066
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
VSA T + V L G ++ R+ A + G A+ PI + + P P
Sbjct: 17067 VVSATVARTTLK-VTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPG--PPG 17122
Query: 179 HLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIR---- 234
T I + + P P G+ L+ + +++SIL+ +
Sbjct: 17123 TPFATAISKDSMVIQWHEPVNNGGSPVI-----GYHLERK-------ERNSILWTKVNKT 17170
Query: 235 -------SAQRSDSG-RYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGC 281
AQ + G YE V E++ +A + V P PP + + V
Sbjct: 17171 IIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRN 17230
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRV 340
LQWT P G + + GY+V+K D G+W T T+S L Y FRV
Sbjct: 17231 EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRV 17290
Query: 341 FSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
++N G + + + I AK + + R S P F + + G + +
Sbjct: 17291 IAKNAAGAISKPSDS-------TGPITAKDEVELPR-ISMDPKFRDTIVVNA---GETFR 17339
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L V P P I W++ EI+ + + + L ++ D G Y +A NV
Sbjct: 17340 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 17399
Query: 461 GEASVDCRLEV 471
G S ++V
Sbjct: 17400 GSKSFPVNVKV 17410
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/199 (29%), Positives = 95/199 (47%), Gaps = 11/199 (5%)
Query: 169 IEAP-KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTHNGHALDSQR--VSMR 223
+E P KI +P+ L GE V+++IPF GKP P TW +D+ +
Sbjct: 24714 VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIV 24773
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T S++F +R D+G Y + + + +++ V + P PP +++ DV +
Sbjct: 24774 TRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSV 24833
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L WT P G +++ Y+V+K +W V + T T+ +L SY FRV +E
Sbjct: 24834 NLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAE 24892
Query: 344 NLCGLS-----TSATVTKE 357
N GLS + T+TKE
Sbjct: 24893 NKFGLSKPSEPSEPTITKE 24911
Score = 85.1 bits (209), Expect = 1e-16
Identities = 98/427 (22%), Positives = 161/427 (37%), Gaps = 48/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + D+V+ + +SW+PP G + Y++E G W+PV+
Sbjct: 10606 RPGPPVGPV-------SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 10658
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + V L G ++ R+ A + G P + D + ++ P P
Sbjct: 10659 SASAKTTCK-VSKLLEGKDYIFRIHAENLYGISDPLVSDS-MKAKDRFRVPD--APDQPI 10714
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSILFIRSAQRSD 240
T + + V P G KP + S+R + T D R +
Sbjct: 10715 VTEVTKDSALVTWNKPHDGG-KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLE 10773
Query: 241 SGRYELTVRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+YE V E+ +K V I KP PP + +D + L W PP+
Sbjct: 10774 GCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRH 10833
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT-----ISDLIIGNSYSFRVFSENLCG 347
G +++LGY+V+ +W + P +C ++ L G +Y FRV + N G
Sbjct: 10834 DGGSKILGYIVEYQKVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAG 10891
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCS 404
S A V P+ + +D E P + G + +L
Sbjct: 10892 ESDPAHV---------------PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAI 10936
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
++ P PK+ W K + K R LEIR + D G+Y+ N G +
Sbjct: 10937 IKGVPFPKVTWKKEDRDAP--TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKT 10994
Query: 465 VDCRLEV 471
V ++ V
Sbjct: 10995 VSVKVLV 11001
Score = 84.7 bits (208), Expect = 2e-16
Identities = 101/423 (23%), Positives = 164/423 (38%), Gaps = 52/423 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP L + + V+++WE P G + GYV+E WV + R
Sbjct: 6783 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 6841
Query: 129 QQTVRNLALGD-KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L G ++L RVSA + G G P D P+ R + P P ++ T + +
Sbjct: 6842 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITDVNR 6899
Query: 188 VGETVNLQIP------------FQGKPKPQATW----THNGHALDSQRVSMRTGDQDSIL 231
G ++ + P + + K W T L + + G + S
Sbjct: 6900 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFR 6959
Query: 232 FIRSAQRSDSGRYELT---VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+R+ R G+ V+V D IE+P PP ++ D + L+W
Sbjct: 6960 -VRAQNRIGVGKPSAATPFVKVAD----------PIERPSPPVNLTSSDQTQSSVQLKWE 7008
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSFRVFSENLCG 347
PP G + +LGY++++ ++ W + P T ++ L GN Y +RV +EN G
Sbjct: 7009 PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG 7068
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+S + + L AD A F+E + +F L P T L S
Sbjct: 7069 VSDPSEILGPLT----ADDA-----FVEPTM-DLSAFKDGL--EVIVPNPITILVPST-G 7115
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN----VLGEA 463
P+P W ++ + + + L I D G+YT K N + GE
Sbjct: 7116 YPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEI 7175
Query: 464 SVD 466
V+
Sbjct: 7176 DVN 7178
Score = 83.6 bits (205), Expect = 4e-16
Identities = 97/430 (22%), Positives = 166/430 (38%), Gaps = 69/430 (16%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + V++ T++W+PP + G + Y++E W V
Sbjct: 16331 RPGPPEGPV-------VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVD 16383
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A ++ + V L G+++ R+ AV+ G G P + +P+ + P P+
Sbjct: 16384 ANVQTLSCK-VTKLLEGNEYTFRIMAVNKYGVGEP-LESEPVVAKNPFVVPD--APKAPE 16439
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQR--- 238
T + T + I +P G+ L+ + D++ I + R +R
Sbjct: 16440 VTTV-----TKDSMIVVWERPASDGGSEILGYVLEKR-------DKEGIRWTRCHKRLIG 16487
Query: 239 ---------SDSGRYELTVRVEDLEA----------KAVIDILVIEKPGPPSSIRLLDVW 279
++ YE V E+ + D I KPGPP++ +++D+
Sbjct: 16488 ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDIT 16545
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW--FTVLERYHPTTCTISDLIIGNSYS 337
+ L W+ P G E+ GY+V+K D G+W T + T + L+ + Y+
Sbjct: 16546 RSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYN 16605
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADH---TST 394
FR+ + N G+ A V P I + EAP L
Sbjct: 16606 FRICAINKAGVGEHADV---------------PGPIIVEEKLEAPDIDLDLELRKIINIR 16650
Query: 395 PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
G S +LF ++ P P++ W K EI+ S +L + + +DSG YT
Sbjct: 16651 AGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTL 16708
Query: 455 KAINVLGEAS 464
N G S
Sbjct: 16709 TLENSSGTKS 16718
Score = 82.8 bits (203), Expect = 6e-16
Identities = 88/406 (21%), Positives = 157/406 (38%), Gaps = 29/406 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + +VS+ T++W PP G ++ Y+LE W VS +
Sbjct: 14166 DVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSC 14224
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ L G++++ RVSAV+ G G P +P+ + + P P + + +
Sbjct: 14225 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPG--PPEKPEVSNVTKN 14281
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
TV+ + P + S R S L + + YE V
Sbjct: 14282 TATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRV 14341
Query: 249 RVEDLE-----AKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+ ++A +L+ + PGPPS+ + D +A+L W P G E+ G
Sbjct: 14342 SAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITG 14401
Query: 301 YMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKEL 358
Y+V+ W T T + DL Y+FR+ + N G+ A +
Sbjct: 14402 YVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-- 14459
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
I + ++A DF + L G S ++F ++ P P++ W K+
Sbjct: 14460 VEIVEREMAP--------DFELDAELRRTLVVRA---GLSIRIFVPIKGRPAPEVTWTKD 14508
Query: 419 KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ ++ + + L I + + +D+G + N G+ S
Sbjct: 14509 NINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 14552
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/411 (21%), Positives = 155/411 (37%), Gaps = 40/411 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ + S +SWEPP G + Y+++ W VSA + +T
Sbjct: 13082 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSAT-VPIT 13140
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+V L G ++ R+ A + G G P + +P + + P P + I +
Sbjct: 13141 SCSVEKLIEGHEYQFRICAENKYGVGDP-VFTEPAIAKNPYDPPGRCDPPVISN--ITKD 13197
Query: 189 GETVNLQIPFQGKPKP------------QATWTHNGHALDSQRVSMRTGDQDSILF---I 233
TV+ + P P WT +R TG Q+ + +
Sbjct: 13198 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 13257
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
+ ++ G+ +KA PGPP+ ++ D + +L W P
Sbjct: 13258 TAINKAGPGK-------PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYD 13310
Query: 294 GNTELLGYMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
G + ++GY+V+ + W + + T ++ L+ Y FRV++ N G S
Sbjct: 13311 GGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13370
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ V + H K DI P+G ++ D + G + +L+ V+ P P
Sbjct: 13371 SDVPDK--HYPK-DILIPPEGELDADLRKTLILRA---------GVTMRLYVPVKGRPPP 13418
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
KI W K + ++ S L + +D+G Y N G+
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 13469
Score = 81.6 bits (200), Expect = 1e-15
Identities = 99/427 (23%), Positives = 165/427 (38%), Gaps = 49/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP V D+VS+ V +SWEPP G + Y++E + W VS
Sbjct: 18099 KPGPPVGPV-------RFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS 18151
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A T + + L G ++ R+ A + G P LD I ++ P + P
Sbjct: 18152 ATVARTTIK-ITKLKTGTEYQFRIFAENRYGKSAP--LDSKAVI---VQYP-FKEPGPPG 18204
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM------RTGDQDSILFIRS 235
++ + + L + + T H ++ S+ +T QD+ ++
Sbjct: 18205 TPFVTSISKDQML-VQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF--KT 18261
Query: 236 AQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAALQWTPP 290
+ YE V E++ + V + V P PP + + N L+W P
Sbjct: 18262 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18321
Query: 291 QDTGNTELLGYMVQKADKKTGQWF-----TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
G +++ GY+V+K D G+W VLE T T+S L+ Y FRV + N
Sbjct: 18322 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLE----TEFTVSGLVEDQRYEFRVIARNA 18377
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
G + + + I D P ++ P + + H G + L +
Sbjct: 18378 AGNFSEPSDSS--GAITARDEIDAPNASLD------PKYKDVIVVHA---GETFVLEADI 18426
Query: 406 RASPKPKIIWMKNKMEIQGN-PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
R P P ++W K+ E++ + S TL ++ D G Y K NV G S
Sbjct: 18427 RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18486
Query: 465 VDCRLEV 471
+ ++V
Sbjct: 18487 IPITVKV 18493
Score = 81.6 bits (200), Expect = 1e-15
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 17/229 (7%)
Query: 251 EDLEAKAVIDILV-IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ LE +V+ I EKPG P + V + + W PP G ++ Y ++K +KK
Sbjct: 24503 DPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKK 24562
Query: 310 TGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAA 368
+W +V E T ++ +LI G Y FRV ENL G S + +++ + K+D+
Sbjct: 24563 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT--PKSDVPI 24620
Query: 369 KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNP-K 427
+AP F + L + + L C V PKP + W + EI + K
Sbjct: 24621 -----------QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24669
Query: 428 YRALS-EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
YR + G L I + D+ VY +A N G S LEV+ A
Sbjct: 24670 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPA 24718
Score = 80.1 bits (196), Expect = 4e-15
Identities = 103/486 (21%), Positives = 178/486 (36%), Gaps = 60/486 (12%)
Query: 4 KNTSEGPACSPEETASESAKVPTAEPPG--EVAVSESTREEQVPKPQAPAPQAPTASTAT 61
K T+ S + S S K + E G E+ VS S VP T
Sbjct: 19131 KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPI---------TIIVLD 19181
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP + +D+VS S+T+SW PPE G + Y++E ++ W VS
Sbjct: 19182 RPGPPGP--------IRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS 19233
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAV-----SSAGAGPPAMLDQPIHIRENIEAPKIRV 176
+ + VR L G ++ RV A SS + + P PK+
Sbjct: 19234 QAVARTSIKIVR-LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV-- 19290
Query: 177 PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSA 236
+ + V Q+P G+ L+ + S + + + I
Sbjct: 19291 ------VHATKSTMLVTWQVPVNDGGSRVI-----GYHLEYKERSSILWSKANKILIADT 19339
Query: 237 QRSDSG-----RYELTVRVEDLE-----AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
Q SG YE V E++ +K+ + + PP + ++ + +L+
Sbjct: 19340 QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLK 19399
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENL 345
W+ P G ++ GY+V++ + G+W T +++L Y FRVF+ N
Sbjct: 19400 WSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNA 19459
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
+ + ++ I D P+ ++ F + G ++ +
Sbjct: 19460 A--DSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI---------VVKAGEVLKINADI 19508
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
P P I W K+ +EI+ + +S L ++ D+G Y NV G SV
Sbjct: 19509 AGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSV 19568
Query: 466 DCRLEV 471
+V
Sbjct: 19569 AVNCKV 19574
Score = 79.7 bits (195), Expect = 5e-15
Identities = 57/211 (27%), Positives = 89/211 (42%), Gaps = 16/211 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + E+P PP I L+DV + +L W P+ G + +LGY+V+ K + +
Sbjct: 15730 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 15789
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T T TI+ LI G YSFRV ++N G+S ++ +
Sbjct: 15790 WAT-CATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV-------------- 15834
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
I +D P+F T G ++ P P + W K+ + ++ + A S
Sbjct: 15835 -IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 15893
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ L I+ D G Y K N GEA
Sbjct: 15894 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924
Score = 79.0 bits (193), Expect = 9e-15
Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 12/205 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P PP +++ D + L W PP++ G + + GY+V++ + + +W E T
Sbjct: 7283 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7342
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
++ L G Y++RV + N G S + T+E IQ D P+ F++ +
Sbjct: 7343 VTGLEEGKWYAYRVKALNRQGASKPSRPTEE---IQAVDTQEAPEIFLD---------VK 7390
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
LA T G +L +V P+PKI W K M ++ + + + T+ I
Sbjct: 7391 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 7450
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
D+G Y +A+NV G A+ + V
Sbjct: 7451 SDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 78.6 bits (192), Expect = 1e-14
Identities = 87/447 (19%), Positives = 169/447 (37%), Gaps = 72/447 (16%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
++P+ PS+ V PS P L + +++ ++ + W PE+ G + Y++E
Sbjct: 7761 SEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDV 7820
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
W V + T+ TV L G ++ RV+A ++ G ++ + ++ P
Sbjct: 7821 RRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP 7879
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
Y V + + + +P N QR + ++ +
Sbjct: 7880 G--------PPYALAVVDVTKRHVDLKWEPPK------NDGGRPIQRYVIEKKERLGTRW 7925
Query: 233 IRSAQRSDSG-RYELTVRVEDLEAKAVI---------------DILVIEKP----GPPSS 272
+++ + + + +T +E E + + +IL IE P PP
Sbjct: 7926 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLD 7985
Query: 273 IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDL-- 330
+ + D + A+ W PP+ G + ++GY V+ T +W V R I DL
Sbjct: 7986 LHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSR------PIKDLKF 8039
Query: 331 ------IIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ Y RV + N G+S + +++ + + +D P+
Sbjct: 8040 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 8084
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
D G + RA P P + W K+ E++ + + ++ LE+ K
Sbjct: 8085 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 8144
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
D+G+YT N LG A+ ++V
Sbjct: 8145 VRADAGIYTITLENKLGSATASINVKV 8171
Score = 77.0 bits (188), Expect = 3e-14
Identities = 92/421 (21%), Positives = 155/421 (36%), Gaps = 53/421 (12%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP + V++ +T+ W PP G + Y++E W VS
Sbjct: 20660 KPGPPGGPIE-------FKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS 20712
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + G++++ RV AV+ G G P D + + +P
Sbjct: 20713 EH-LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPE--- 20768
Query: 182 QTYIRQVGETVNLQIPF------------QGKPKPQATWTH--NGHALDS-QRVSMRTGD 226
T I + TV P + + K W D+ Q+V+ T +
Sbjct: 20769 VTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTEN 20828
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
D + + + G + E E D I+ PGPP+ IR+ D + L
Sbjct: 20829 SDYQYRVCAVNAAGQGPFS-----EPSEFYKAAD--PIDPPGPPAKIRIADSTKSSITLG 20881
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSEN 344
W+ P G + + GY+V+ + +W TV + T +S+L G +Y FRV + N
Sbjct: 20882 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVN 20941
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTST---PGYSTQL 401
G + + + +D EAP +A TS G Q+
Sbjct: 20942 CAGQGEPIEMNEPVQ---------------AKDILEAPEIDLDVALRTSVIAKAGEDVQV 20986
Query: 402 FCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P P + W K++ + + +Y + L I + + D+G Y N +G
Sbjct: 20987 LIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 21046
Query: 462 E 462
E
Sbjct: 21047 E 21047
Score = 75.9 bits (185), Expect = 8e-14
Identities = 60/238 (25%), Positives = 98/238 (41%), Gaps = 24/238 (10%)
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
+ +I + R ++ G + V VE ++A + E P PP + L DV +A+L
Sbjct: 17876 EGAIYYFRVMAENEFG---VGVPVETVDA-----VKAAEPPSPPGKVTLTDVSQTSASLM 17927
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W P+ G + +LGY+V+ K T +W V E ++ L G Y FRV + N
Sbjct: 17928 WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQEYQFRVKAYNEK 17986
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
G K+D I +D + PS P ++ G ++ V
Sbjct: 17987 G---------------KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVI 18031
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P+P I W+K+ ++ + L I++ + D G YT A N G A+
Sbjct: 18032 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 18089
Score = 74.7 bits (182), Expect = 2e-13
Identities = 95/428 (22%), Positives = 168/428 (39%), Gaps = 54/428 (12%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PPS+ P P+ D++ + SV +SW+ PE G + Y +E + W V +
Sbjct: 21351 PPSK--PKGPI--RFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21406
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTY 184
T + V NL ++ RV A + G + QP+ + + R+P
Sbjct: 21407 ARTTFK-VPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPG------ 21453
Query: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR- 243
G+ V + G ++G + + + +++SIL+ + SGR
Sbjct: 21454 --PPGKPVIYNVTSDGMSLTWDAPVYDGGS-EVTGFHVEKKERNSILWQKVNTSPISGRE 21510
Query: 244 YELTVRVEDLE-------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
Y T VE L+ +K + + ++ PG P I DV
Sbjct: 21511 YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETIT 21567
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L+W PP G ++++GY ++K T++ L G+ Y FR+ + N
Sbjct: 21568 LKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARN 21627
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G T + ++ I D P +E P + L + G S ++
Sbjct: 21628 AVG--TISPPSQSSGIIMTRDENVPP--IVEF----GPEYFDGLIIKS---GESLRIKAL 21676
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V+ P P++ W K+ +EI+ G +L +R + GVYT +A N G A
Sbjct: 21677 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21736
Query: 465 VDCRLEVK 472
+ +++V+
Sbjct: 21737 AEIKVKVQ 21744
Score = 72.8 bits (177), Expect = 6e-13
Identities = 91/421 (21%), Positives = 155/421 (36%), Gaps = 39/421 (9%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ L ++ +++ ++SW P+ G + Y++E W +
Sbjct: 19577 KPGPPAGP-------LEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-IC 19628
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ +T V L G++++ RV+ V+ G G P + I + P P L
Sbjct: 19629 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP-LESVAIKALDPFTVPS--PPTSLE 19685
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDS 241
T + + T+ P + + +S R L ++S +
Sbjct: 19686 ITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREG 19745
Query: 242 GRYELTVRVED---LEAKAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
YE V E+ L + L+ + P PPS +++D + W P
Sbjct: 19746 CEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFD 19805
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
G + GY V+ W T ++ T TIS L G Y FRV S N G S +
Sbjct: 19806 GGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSD 19865
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCSVRASPK 410
++ P+ I ++ E P F ++ G S + R P
Sbjct: 19866 -------------SSDPQ--IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 19910
Query: 411 PKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
P ++W K +++ + T+E + DSG YT NVL AS+ ++
Sbjct: 19911 PNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRN--DSGKYTLTIQNVLSAASLTLVVK 19968
Query: 471 V 471
V
Sbjct: 19969 V 19969
Score = 72.4 bits (176), Expect = 8e-13
Identities = 49/217 (22%), Positives = 89/217 (41%), Gaps = 16/217 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ I V E P PP I + DV + +L WT P+ G ++++ Y+V+ K + +
Sbjct: 16812 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEK 16871
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W + R I++L G Y FRV + N G S ++ +
Sbjct: 16872 W-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI-------------- 16916
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+ +D P + ++ G ++ + PKP I W K+ + ++ +
Sbjct: 16917 -VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTD 16975
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRL 469
+ TL I++ D G Y NV+G+ + +
Sbjct: 16976 SLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 17012
Score = 71.2 bits (173), Expect = 2e-12
Identities = 68/289 (23%), Positives = 112/289 (38%), Gaps = 12/289 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + DV++ S ++W PP G + YV+E + W +S+ + T
Sbjct: 7477 DKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSS-TVKDT 7535
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
L +++ RV+A + G G P PI + + P P L + I +
Sbjct: 7536 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA-SPITAKYQFDPP--GPPTRLEPSDITKD 7592
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
T+ P P + D+ + R ++ +Y V
Sbjct: 7593 AVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRV 7652
Query: 249 RVEDL-----EAKAVIDILV---IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+L +K+ IL+ I+ P PP + DV + L WT P+ G ++
Sbjct: 7653 LAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIES 7712
Query: 301 YMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+++ T +W V E T + L+ G YSFRV + N G S
Sbjct: 7713 YVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 7761
Score = 69.3 bits (168), Expect = 7e-12
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 20/215 (9%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + V E P PP + L+DV A ++W P+ G +++ GY+V+ K + +
Sbjct: 18977 LPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEK 19036
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T + TIS L G Y FRV + N G ++D
Sbjct: 19037 WSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKG---------------RSDPRQLGVP 19080
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV--RASPKPKIIWMKNKMEIQGNPKYRA 430
I RD PS P HT QL V + P+ + W K+ ++ +
Sbjct: 19081 VIARDIEIKPSVELPF--HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNV 19138
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
S + V +L I++ S D G Y N G +V
Sbjct: 19139 SSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 19173
Score = 68.2 bits (165), Expect = 2e-11
Identities = 97/427 (22%), Positives = 157/427 (36%), Gaps = 57/427 (13%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSARPMM 126
D P P+ +D+ +SV WEPP G + Y LE + SEW+ V++ +
Sbjct: 8495 DTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTS-TLR 8553
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR 186
+ +V L G ++L RV A + G GPP + +P+ ++ P + +
Sbjct: 8554 HCKYSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAP-----DKPIVE 8607
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG---- 242
V T N + +PK + G+ L+ + V+ + + + + + + G
Sbjct: 8608 DV--TSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 8664
Query: 243 -RYELTVRVEDL----------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
Y V E+ + K D I PGPP R+ D L+W PP
Sbjct: 8665 LTYVFRVCAENAAGPGKFSPPSDPKTAHD--PISPPGPPIP-RVTDTSSTTIELEWEPPA 8721
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGL-- 348
G E++GY V K T +W E+ T+ ++ G Y RV + N G
Sbjct: 8722 FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGP 8781
Query: 349 --STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
T E ++ KG I+ G + ++ V
Sbjct: 8782 PGETQPVTVAEPQEPPAVELDVSVKGGIQ-----------------IMAGKTLRIPAVVT 8824
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQ--GVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P +W K + E+ K R + + L I+ D G Y A N G
Sbjct: 8825 GRPVPTKVWTKEEGELD---KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 8881
Query: 465 VDCRLEV 471
R+EV
Sbjct: 8882 AAARVEV 8888
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/235 (22%), Positives = 94/235 (40%), Gaps = 30/235 (12%)
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
F R ++ G E T E ++A E P PP S+ ++D+ +L W P+
Sbjct: 14633 FFRVMAENEYGIGEPTETTEPVKAS--------EAPSPPDSLNIMDITKSTVSLAWPKPK 14684
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS-- 349
G +++ GY+++ K + QW T + C + +L G Y+F+V + N G S
Sbjct: 14685 HDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 14743
Query: 350 --TSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+ + KE + + D+ + + + G + ++ V
Sbjct: 14744 RESRPVIVKEQTMLPELDLRGIYQKLV-----------------IAKAGDNIKVEIPVLG 14786
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
PKP + W K ++ + + L I + DSG Y A N++GE
Sbjct: 14787 RPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 14841
Score = 66.6 bits (161), Expect = 5e-11
Identities = 85/431 (19%), Positives = 158/431 (36%), Gaps = 63/431 (14%)
Query: 69 DVPSAPLL-LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D P P + D+ + + ++SW P G + Y++E C +WV A +
Sbjct: 12685 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTK 12743
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T V L G +++ RV A + G + +P+ + + VP + + +
Sbjct: 12744 TSCRVGKLIPGQEYIFRVRAENRFG------ISEPLTSPKMVAQFPFGVPSEPKNARVTK 12797
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRS-DSGRYEL 246
V N F +P + G + + + +++S+L++++ S Y
Sbjct: 12798 V----NKDCIFVAWDRPDSD---GGSPIIGYLIERK--ERNSLLWVKANDTLVRSTEYPC 12848
Query: 247 TVRVEDLEAKAVIDILVIEKPG------------------PPSSIRLLDVWGCNAALQWT 288
VE LE I + K G PP ++DV +L W
Sbjct: 12849 AGLVEGLEYS--FRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWA 12906
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
P+ G ++++GY V+ +W T + T + L Y FR +
Sbjct: 12907 RPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTA 12966
Query: 346 CGLSTSATVTKELAHIQ-----KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
+S + + + + + D++ K + T G +
Sbjct: 12967 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL-----------------TVKAGTNVC 13009
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L +V P P + W K+ ++ + ++ +CTLE+ + DSG YT A N
Sbjct: 13010 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 13069
Query: 461 GEASVDCRLEV 471
G S +L+V
Sbjct: 13070 GSKSATIKLKV 13080
Score = 66.2 bits (160), Expect = 6e-11
Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 31/222 (13%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-----KADKKTGQWFTVLE 318
I P PP +++ + L W PP++ G + + Y+V+ K W +
Sbjct: 9704 IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK 9763
Query: 319 R-YHPTTCTISDLIIGNSYSFRVFSENLCGLST-SATVTKELAHIQKADIAAKPKGFIER 376
R T+ DL+ G Y FRV + N G+S SATV Q+ D+ P +
Sbjct: 9764 RDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGP--CDCQRPDM---PPSIDLK 9818
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK-------NKMEIQGNPKYR 429
+F E G + + ++ P P + W K NK + +
Sbjct: 9819 EFMEVEE------------GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN 9866
Query: 430 ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L CTL I + D+G+YT A+N LG AS + RL V
Sbjct: 9867 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9908
Score = 66.2 bits (160), Expect = 6e-11
Identities = 91/429 (21%), Positives = 169/429 (39%), Gaps = 73/429 (17%)
Query: 77 LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLA 136
+ + VS+ S +SW P+ G + Y++E G + W V++ + TQ V +L
Sbjct: 22443 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLT 22501
Query: 137 LGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQI 196
++ RVS+ + G P L+ I E+ P P ++ ++ +
Sbjct: 22502 KYMEYSFRVSSENRFGVSKP--LESAPIIAEHPFVPP-SAPTRPEVYHVSANAMSIRWEE 22558
Query: 197 PFQ-GKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSD-SGRYELTVRVEDLE 254
P+ G K W ++++IL+++ + Y++T VE LE
Sbjct: 22559 PYHDGGSKIIGYWVEKK-------------ERNTILWVKENKVPCLECNYKVTGLVEGLE 22605
Query: 255 -------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
++ ++ ++ PG P + DV +L W+ P G
Sbjct: 22606 YQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VTDVTRSTVSLIWSAPAYDGG 22662
Query: 296 TELLGYMVQK---ADKKTGQW----FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++++GY++++ ++ G+W +T++ T +S+ G++Y FRV ++N G+
Sbjct: 22663 SKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE---GDTYEFRVLAKNAAGV 22719
Query: 349 ------STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
ST ++ KA++ A+ G + T G L
Sbjct: 22720 ISKGSESTGPVTCRDEYAPPKAELDARLHGDLV----------------TIRAGSDLVLD 22763
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
+V P+PKIIW K E+ K T I+ DSG YT N G
Sbjct: 22764 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 22823
Query: 463 ASVDCRLEV 471
+V ++V
Sbjct: 22824 KAVSVMVKV 22832
Score = 65.1 bits (157), Expect = 1e-10
Identities = 92/432 (21%), Positives = 162/432 (37%), Gaps = 47/432 (10%)
Query: 56 TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
T +P PP PL +T V++ ++W PP + G + Y++E
Sbjct: 18490 TVKVLDRPGPPE-----GPLKVT--GVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL 18542
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP--- 172
W VS + + V L G++++ RV AV+ G G P + P+ + P
Sbjct: 18543 SWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEP-LESGPVTACNPYKPPGPP 18600
Query: 173 -----KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRT 224
+ T+ R V G T + + K WT N L R+ +
Sbjct: 18601 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 18660
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
+ R A + +G E + E D L PGPPS+ ++ D + +
Sbjct: 18661 LTEGHSYEFRVAAENAAGVGEPS---EPSVFYRACDALY--PPGPPSNPKVTDTSRSSVS 18715
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-----TISDLIIGNSYSFR 339
L W+ P G + GY+V+ + +W T PT T++ L Y+FR
Sbjct: 18716 LAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP---PTGLQGKQFTVTKLKENTEYNFR 18772
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
+ + N G+ AT+ + ++ + P+ ++ D + +
Sbjct: 18773 ICAINSEGVGEPATLPGSVVAQERIE---PPEIELDADLRKVVVLRASA---------TL 18820
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
+LF +++ P+P++ W K + + + S L I + FDSG Y N
Sbjct: 18821 RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTLENN 18878
Query: 460 LGEASVDCRLEV 471
G + + V
Sbjct: 18879 SGSKTAFVNVRV 18890
Score = 63.2 bits (152), Expect = 5e-10
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Query: 59 TATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASE 116
T +KP A D P P + VS +TV W PPE G + GY LE + ++
Sbjct: 12077 TESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 12136
Query: 117 WVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WVPV+ + + V+NL ++ RV A + G G P++ +P+ ++ IE P
Sbjct: 12137 WVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP 12192
Score = 63.2 bits (152), Expect = 5e-10
Identities = 53/201 (26%), Positives = 82/201 (40%), Gaps = 5/201 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P L + +S SVT+ WE PE G + GY +E + G S W + +
Sbjct: 24124 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 24183
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR-ENIEAPKIRVPRHLRQTYIRQ 187
Q T+ L ++ RV A + G P I + + EAP IR + +
Sbjct: 24184 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTK 24240
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
+GE L G+P P W G L S++ M + + L + + ++ D G Y
Sbjct: 24241 LGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 24300
Query: 247 TVRVEDLEAKAVIDILVIEKP 267
E E + +L+ P
Sbjct: 24301 IATNEVGEVETSSKLLLQATP 24321
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 25/211 (11%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+LV E P P+ + ++DV L W P G + L GY+++ T +W V+
Sbjct: 23324 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT-L 23382
Query: 321 HPTTC--TISDLIIGNSYSFRVFSENLCGLS-----TSATVTKELAHIQKADIAAKPKGF 373
PT T++ L G Y FR+ ++N G+S +A ++L + D++ P+
Sbjct: 23383 KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKT 23442
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I P+ G +L + P P W +++ + + +
Sbjct: 23443 IH-----VPA------------GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 23485
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V L IR+ + D+G YT + NV G S
Sbjct: 23486 TKVAKLTIRETTIRDTGEYTLELKNVTGTTS 23516
Score = 61.6 bits (148), Expect = 1e-09
Identities = 33/103 (32%), Positives = 55/103 (53%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + DVS +T++W PPE G + GY++E A WV V+ P+ +T+
Sbjct: 23626 IPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 23685
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
L G ++ RV+A+++ G+G P+ +PI + I P
Sbjct: 23686 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPP 23728
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/104 (32%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV-SARPMMVT 128
VP AP + +++ +S+T++W PE G +Q Y+LE + ++ WV V S RP+ T
Sbjct: 21846 VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISET 21905
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ V L G+++ V A ++AG GP + + + I RE + P
Sbjct: 21906 RFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 21949
Score = 58.5 bits (140), Expect = 1e-08
Identities = 62/272 (22%), Positives = 104/272 (38%), Gaps = 34/272 (12%)
Query: 208 WTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKP 267
WT + + Q +++ Q F R A + G VE EA + + + + P
Sbjct: 10358 WTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPF---VETSEALVIREPITV--P 10412
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT--- 324
P + + +V L W PP+ G +E++ Y+++ T E++H T
Sbjct: 10413 ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT-------EKFHKVTNDN 10465
Query: 325 -----CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFS 379
T+ L G++Y +RV + N+ G + TK I D A P + DF
Sbjct: 10466 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAPPT--LHLDFR 10520
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
+ T G + L PKPK+ W K++ ++ + + + L
Sbjct: 10521 DKL---------TIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLAL 10571
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
E K DSG Y N G C++ V
Sbjct: 10572 EKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10603
Score = 58.5 bits (140), Expect = 1e-08
Identities = 64/267 (23%), Positives = 100/267 (37%), Gaps = 32/267 (11%)
Query: 207 TWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
TW+ H S + + + F R ++ G E E ++A V
Sbjct: 21106 TWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV-------- 21157
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P P + + D + L WT P G + + Y+V++ K W TC
Sbjct: 21158 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWS---HAGISKTCE 21214
Query: 327 I--SDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
I S L + FRVF++N GLS T+ I ++ P E D S+ P
Sbjct: 21215 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----GPITVKELIITP----EVDLSDIPG- 21265
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
A T G++ L + PKP I W+K+ + ++ + R + TL I+
Sbjct: 21266 ----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21321
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
G YT N + CR+ V
Sbjct: 21322 KKEHGGKYTVILDNAV------CRIAV 21342
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPM---- 125
VP AP T+ V+ +S+TV+WE PE G + GY LE+ + W V+ P+
Sbjct: 10011 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 10070
Query: 126 MVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
+ V L G + RV A+++AG GP ++ P R+ I P P+
Sbjct: 10071 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPK 10123
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/104 (29%), Positives = 52/104 (50%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP AP + DV SV+++W P++ G + GY LE + W + P+ +
Sbjct: 13869 DVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMR 13928
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ RV A++ AG G P++ +P+ + I+ P
Sbjct: 13929 DFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13972
Score = 57.8 bits (138), Expect = 2e-08
Identities = 48/208 (23%), Positives = 79/208 (37%), Gaps = 27/208 (12%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
I+ E+P PP + ++D +A L W P G + + GY+++ K + W +E
Sbjct: 22235 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW---VEAG 22291
Query: 321 H--PTTCTISDLIIGNSYSFRVFSENLCGLST-----SATVTKELAHIQKADIAAKPKGF 373
H T T+ L+ Y FRV ++N G S S+ + KE AD+
Sbjct: 22292 HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL 22351
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I T G + + P PK+ W +M ++ + +
Sbjct: 22352 I-----------------TCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTT 22394
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ TL ++ DSG Y N G
Sbjct: 22395 KDRTTLTVKDSMRGDSGRYFLTLENTAG 22422
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/98 (31%), Positives = 44/98 (44%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
+ ++ S+AP+F G + C + P P+I W KN + I +
Sbjct: 26821 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 26880
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ V +LEIR S DSG YT KA N G+ S L V
Sbjct: 26881 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/93 (30%), Positives = 44/93 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ L + T G S L C + P P + W + +I+ + ++ + G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
R+ DSG +TC A+N G S C L V+ S
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 57.4 bits (137), Expect = 3e-08
Identities = 55/218 (25%), Positives = 89/218 (40%), Gaps = 27/218 (12%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT-- 324
PGPPS + D + +L W PP G + + GY+V+ ++ T W V E T
Sbjct: 9400 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9459
Query: 325 -CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
C + +L Y FRV + N G S + T E I DI +P+ FI+ +
Sbjct: 9460 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGE---IPATDIQEEPEVFIDIGAQDCL- 9515
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIW---------MKNKM-EIQGNPKYRALSE 433
G ++ ++ P PK W MK+ + +I + +
Sbjct: 9516 --------VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAEN 9567
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
V + K S +G Y+ A N G+ + +CR++V
Sbjct: 9568 SSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 9603
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 1/153 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P AP T+ V+ S V+W+PP G ++ Y LE + ++W+ V+ + T
Sbjct: 24520 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 24579
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
+V+NL G ++ RV + G + + +PI + ++ LR +R
Sbjct: 24580 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVR-YQS 24638
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMR 223
L G PKP W G + + + R
Sbjct: 24639 NATLVCKVTGHPKPIVKWYRQGKEIIADGLKYR 24671
Score = 56.6 bits (135), Expect = 5e-08
Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
+T +TVT++ +PK S P L D T + +
Sbjct: 26526 TTESTVTRK----------TEPKA--PEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGE 26573
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P+P IW K+ I KY+ ++G LEI K DSG+YTC N G S C+
Sbjct: 26574 PRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCK 26633
Query: 469 LEVKA 473
L +KA
Sbjct: 26634 LTIKA 26638
Score = 55.8 bits (133), Expect = 8e-08
Identities = 57/237 (24%), Positives = 85/237 (35%), Gaps = 46/237 (19%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-T 323
+ P PP + + + + W PP G ++++GY+++K K +W E P
Sbjct: 8273 QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL 8332
Query: 324 TCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
T T L G Y FRV +EN G+S + T + D PK +
Sbjct: 8333 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPID---APKVILRTSLE---- 8385
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN--------------------KMEIQ 423
G L S+ SP P I W+K+ K E+Q
Sbjct: 8386 ---------VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQ 8436
Query: 424 GN-----PKYRAL----SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
P + L S++G L +R D G+Y K N G A C + V
Sbjct: 8437 EEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493
Score = 55.1 bits (131), Expect = 1e-07
Identities = 51/211 (24%), Positives = 84/211 (39%), Gaps = 26/211 (12%)
Query: 258 VIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
++ I I++PG P ++ + D L+W P G + L Y V++ K + W V
Sbjct: 11787 ILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH 11846
Query: 318 ERYHPTTCTISDLIIGNS-YSFRVFSENLCG----LSTSATVTKELAHIQKADIAAKPKG 372
+ T + D + N Y FRV ++N G + T V KE +QK + K G
Sbjct: 11847 KGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKE--DLQKPVLDLKLSG 11904
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK--MEIQGNPKYRA 430
+ T G + +L VR P P++ W K+K ++ +P+ +
Sbjct: 11905 VL-----------------TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11947
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ + K D G Y A N G
Sbjct: 11948 DTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11978
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PSAP+ LT+ +V SVT+SWEPP G + Y++E RE + T
Sbjct: 18892 DSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEK-RETTRKAYATITNNCTKT 18950
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ NL G + RV A + G G PA +P+ + E
Sbjct: 18951 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE 18989
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/201 (20%), Positives = 82/201 (40%), Gaps = 13/201 (6%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+ + EKP PP + + + + +L W P+ G + ++ Y+V+ +K W
Sbjct: 20064 VKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA- 20122
Query: 321 HPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE 380
T +S L + Y FRVF+EN GLS + + ++ + E D
Sbjct: 20123 KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPP-------EIDMKN 20175
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
PS T + G + ++ + P PK+ ++ + ++ ++ T+
Sbjct: 20176 FPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTIN 20230
Query: 441 IRKPSPFDSGVYTCKAINVLG 461
+++ D+G Y A N G
Sbjct: 20231 LKESVTADAGRYEITAANSSG 20251
Score = 53.1 bits (126), Expect = 5e-07
Identities = 46/197 (23%), Positives = 82/197 (41%), Gaps = 16/197 (8%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT 324
+ PGP +++ V + ++ W P G + ++GY+V ++ +W V++
Sbjct: 13577 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQ 13634
Query: 325 CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ DL G Y+FRV +EN G T + +T + + D+ A + D P
Sbjct: 13635 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV----VARDDVVAP-----DLDLKGLPDL 13685
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
LA S + +L ++ P P + W K + + + + S TL +
Sbjct: 13686 CY-LAKENS----NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 13740
Query: 445 SPFDSGVYTCKAINVLG 461
D+G YT NV G
Sbjct: 13741 QKSDAGKYTITLKNVAG 13757
Score = 53.1 bits (126), Expect = 5e-07
Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
Query: 55 PTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P S A K P VPS P L + V+ S+T+ W PE G + GY++E + +
Sbjct: 19663 PLESVAIKALDPFT-VPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNS 19721
Query: 115 SEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WV V+ +P+ + L G ++ RV A ++AG P+ I + + P
Sbjct: 19722 LRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19779
Score = 52.8 bits (125), Expect = 7e-07
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 19/154 (12%)
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T + + + + R G Y ++ E +E ++ I I PGPP ++++ DV
Sbjct: 23592 TEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGM 23643
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV------LERYHPTTCTISDLIIGNSYS 337
L W PP+D G +++ GY+V++ + + +W V + RY T L G Y
Sbjct: 23644 TLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRST-----GLTEGLEYE 23698
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPK 371
RV + N G + +K + + KP+
Sbjct: 23699 HRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQ 23732
Score = 52.4 bits (124), Expect = 9e-07
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DV+ +S VSW PPE G + Y++E W V+ + T
Sbjct: 12392 DTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPE-VKKT 12450
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V NL G+++ RV+AV+ G G P + +P+ + + P PR L T + +
Sbjct: 12451 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPD--PPRKLEVTEMTKN 12508
Query: 189 GETV 192
T+
Sbjct: 12509 SATL 12512
Score = 52.4 bits (124), Expect = 9e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE+ V+ PGPP S+ + ++ + + W P G +E++GY+V+K D+
Sbjct: 17498 EPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSG 17557
Query: 311 GQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+W R ++ L + Y FRV +EN G+ + T
Sbjct: 17558 IRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17603
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/91 (32%), Positives = 43/91 (47%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP T + H G +T+ +V++ P ++ W N +E+Q + K + GV TLE
Sbjct: 26068 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 26127
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
I DSG Y N GEAS L+V
Sbjct: 26128 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/287 (21%), Positives = 105/287 (36%), Gaps = 19/287 (6%)
Query: 200 GKPKPQATWTHNGHALDS---QRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAK 256
G PKP W +G L + +VS + L I D+G Y + VR + E
Sbjct: 1061 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1120
Query: 257 AVIDIL------VIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK- 309
A +L ++ K S +L A +Q +T G++ + +K+
Sbjct: 1121 ASASLLEEADYELLMK----SQQEMLYQTQVTAFVQEPKVGETAP----GFVYSEYEKEY 1172
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK 369
+ + ++ T + + + F E L + L + + D K
Sbjct: 1173 EKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEK 1232
Query: 370 PKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR 429
I + F + ++ G C + P PKI W K+ I+ +Y+
Sbjct: 1233 MAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQ 1292
Query: 430 A-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ G +L I P D G+YT A N+ G A +L V+ +A
Sbjct: 1293 MDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAA 1339
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/225 (24%), Positives = 85/225 (37%), Gaps = 30/225 (13%)
Query: 261 ILVIEKPGPPSSIRLL---DVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
IL ++ GPP+S L + L W P+ G + + GY+++K + V
Sbjct: 8981 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 9040
Query: 318 ERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIER 376
+R PTT + +L Y FRV + N G S + P + +
Sbjct: 9041 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNVVIQ 9084
Query: 377 DFSEAPSFTQPLADHTST----PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D P+ L+ T G + V P PKI W KN+ I+ ++
Sbjct: 9085 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 9144
Query: 433 EQGV------CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ V L I K D G YT A N LG + +EV
Sbjct: 9145 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9189
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T+ DV+ S +SW+ PE G ++ Y +E WV V+ ++
Sbjct: 19971 DTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLS 20030
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+ V NL G + RVS + G G PA + + I E P+
Sbjct: 20031 YK-VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 20074
Score = 50.8 bits (120), Expect = 3e-06
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T DV+ S T+ W+ P G + YV+E W +S + T
Sbjct: 22142 DTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK---CT 22198
Query: 129 QQ--TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+Q V +LA G + RVSAV+ G G P + +PI E P+
Sbjct: 22199 RQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPR 22245
Score = 50.4 bits (119), Expect = 3e-06
Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE++ V+ + P PP + + + + + W P G +E++ Y+V++ DK
Sbjct: 15334 EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAG 15393
Query: 311 GQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
+W ++ +S L G+ Y FR+ +EN G+S
Sbjct: 15394 QRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 15433
Score = 48.5 bits (114), Expect = 1e-05
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 12/196 (6%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P+ L + +++ SV+++WEPP G ++ Y++E RE +
Sbjct: 16727 DTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK-REATRKSYAAVVTNCHKN 16785
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP-KIRVPRHLRQ----- 182
+ L G + RV+A + G G PA PI + E + P KI V R
Sbjct: 16786 SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLS 16845
Query: 183 -TYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF----IRSAQ 237
T G + +Q + + K W+ Q V + LF +
Sbjct: 16846 WTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKG 16905
Query: 238 RSDSGRYELTVRVEDL 253
RSD + + +DL
Sbjct: 16906 RSDPRSLAVPIVAKDL 16921
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
D++ SS ++WEPPE G + YVLE G ++PV + ++ TV++L +
Sbjct: 8185 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGE 8243
Query: 141 FLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ RV AV+ G G L P+ ++ + P
Sbjct: 8244 YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8275
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/199 (21%), Positives = 75/199 (37%), Gaps = 17/199 (8%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-KADKKTGQWFTVLERYHP 322
+ +P PP + + ++ +A L W PP G ++ GY+ + +++ +T
Sbjct: 12491 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 12550
Query: 323 TTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAP 382
+ ++ L G Y FRV + N G+S + +E + +A P P
Sbjct: 12551 LSLVVTGLKEGKKYKFRVAARNAVGVS----LPREAEGVYEAKEQLLP-----------P 12595
Query: 383 SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
P T G ++ V P P W K + E+ + L I+
Sbjct: 12596 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12654
Query: 443 KPSPFDSGVYTCKAINVLG 461
+ DSG Y+ A N G
Sbjct: 12655 DVTRKDSGYYSLTAENSSG 12673
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC--REGASEWVPVSARPMM 126
D P+ P+++ + + +S +SW+PP G + YV+E C +EGA EW VS+ +
Sbjct: 24419 DKPTGPIVI--EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGA-EWQLVSS-AIS 24474
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
VT + NL + RVSA ++ G P + + I+ E P
Sbjct: 24475 VTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP 24520
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + DVS SV ++W P G + Y++E C A W+ V T
Sbjct: 24815 DVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARET 24872
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
+ TV NL + RV A + G P+ +P +E+
Sbjct: 24873 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKED 24912
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 83 SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP-----MMVTQQTVRNLAL 137
+ S+ VSW PP G + GY LE EG+ W VS P + + V L
Sbjct: 9306 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9365
Query: 138 GDKFLLRVSAVSSAGAGPPAMLDQP 162
G K+ R A+++AG GPP+ P
Sbjct: 9366 GVKYQFRAMAINAAGIGPPSEPSDP 9390
Score = 47.0 bits (110), Expect = 4e-05
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 14/144 (9%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T P PPS + +V+ S+TV W P G + GY LE+ + W
Sbjct: 20363 TTPGPPSTP--------WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKA 20414
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + T V ++ G + RV A ++AG G P+ +P+ + E PR++
Sbjct: 20415 NKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP-----PRNV 20469
Query: 181 RQTYIRQVGETVNLQIP-FQGKPK 203
R T I + +++ Q P F G K
Sbjct: 20470 RITDISKNSVSLSWQQPAFDGGSK 20493
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T P P E + P +L DV+ SSV++SW P+ G + GY +E +WV
Sbjct: 24016 TPKTPLNPPEPPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWV 24072
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ + T TV L ++ R+ A + G + +P+ ++ + P
Sbjct: 24073 RHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKP 24126
Score = 46.6 bits (109), Expect = 5e-05
Identities = 39/129 (30%), Positives = 52/129 (40%), Gaps = 10/129 (7%)
Query: 355 TKELAHIQKADIAA---------KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
TKEL +K +A KP EAP + + T G V
Sbjct: 1996 TKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV 2055
Query: 406 RASPKPKIIWMKNKMEIQGNPK-YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P+ W KN ++I+ + + Y E VC L IR + DS KAIN+ GE S
Sbjct: 2056 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2115
Query: 465 VDCRLEVKA 473
L V+A
Sbjct: 2116 SHAFLLVQA 2124
Score = 46.6 bits (109), Expect = 5e-05
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ---GNPKYRALSEQGVCT 438
P FT PL + T+ G + + ++ P+P + W K+ +I+ + KY S++G+
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L I + D YT A N GE S +L V
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/76 (31%), Positives = 36/76 (47%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G+ + C ++++P + W K EI + K S + + +LEI + D G YTCK
Sbjct: 4543 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 4602
Query: 456 AINVLGEASVDCRLEV 471
A N G S L V
Sbjct: 4603 ASNEYGSVSCTATLTV 4618
Score = 46.2 bits (108), Expect = 6e-05
Identities = 42/153 (27%), Positives = 61/153 (39%), Gaps = 3/153 (1%)
Query: 20 ESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTL 79
E A++ TAE + + E R K A TA DVP P L +
Sbjct: 9558 EDAQLETAENSSVIIIPECKRSH-TGKYSITAKNKAGQKTANCRVKVM-DVPGPPKDLKV 9615
Query: 80 DDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGD 139
D++ S +SW+ P+ G ++GYV+E W V+ T V +L
Sbjct: 9616 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNP-DCGSTTFVVPDLLSEQ 9674
Query: 140 KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
++ RV A + G GPP Q R+ I P
Sbjct: 9675 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 9707
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/88 (27%), Positives = 43/88 (48%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + +++ S+TV W P+ G + GY++E W+ + R + +
Sbjct: 17513 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 17572
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPA 157
V L ++ RVSA ++AG G P+
Sbjct: 17573 LRVTGLTEDHEYEFRVSAENAAGVGEPS 17600
Score = 46.2 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
PSAP + VS++++++ WE P G + GY +E WV + P +
Sbjct: 22536 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22595
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ R A+++AG + +PI + ++AP
Sbjct: 22596 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 22637
Score = 45.8 bits (107), Expect = 8e-05
Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 241 SGRYELTVRVED---LEAKAVIDILVIEKP----GPPSSIRLLDVWGCNAALQWTPPQDT 293
+G+YE VR + + + D +VI+ P GPP ++L + + WTPP D
Sbjct: 9261 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 9320
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTT--------CTISDLIIGNSYSFRVFSENL 345
G + + GY ++K ++ + W V P T + L+ G Y FR + N
Sbjct: 9321 GGSPITGYWLEKREEGSPYWSRVSRA--PITKVGLKGVEFNVPRLLEGVKYQFRAMAINA 9378
Query: 346 CGL 348
G+
Sbjct: 9379 AGI 9381
Score = 45.8 bits (107), Expect = 8e-05
Identities = 60/300 (20%), Positives = 105/300 (35%), Gaps = 40/300 (13%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ V G+P P+ W N + S VS+ L IR+A SDSG+Y +
Sbjct: 26843 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 26902
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG----YMV 303
+ + A ++V+ PS +L + +G+T L G V
Sbjct: 26903 AKNFRGQCSATASLMVLPLVEEPSREVVL--------------RTSGDTSLQGSFSSQSV 26948
Query: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSF--------RVFSENLCGLSTSATVT 355
Q + K F+ ++ T ++ S + S + G+S +
Sbjct: 26949 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 27008
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ + KA I P P +D + G + C+ P P++ W
Sbjct: 27009 SSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTW 27057
Query: 416 M--KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
K+ Q ++ + + TL I D G+YT N G S + +++
Sbjct: 27058 SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27117
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P P + K D P P++ +DV+S+S+ V W P+ G + GY LE
Sbjct: 8580 PGPPCVSKPLVAKDPFGPPDAPDKPIV---EDVTSNSMLVKWNEPKDNGS-PILGYWLEK 8635
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
++ W V+ + + V L G ++ RV A ++AG G + P + I
Sbjct: 8636 REVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPI 8695
Query: 170 EAPKIRVPR 178
P +PR
Sbjct: 8696 SPPGPPIPR 8704
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/93 (30%), Positives = 41/93 (44%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E P Q L T G + + P+PKI W K + + K + L + TL
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + P D+ VYTC+A N G A+ L V+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+PL D T G + L C V + K+ W KN EI + KY +++ V L I
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 6040
Query: 444 PSPFDSGVYTCKA 456
+P D YTC A
Sbjct: 6041 CTPEDIKTYTCDA 6053
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGVCTL 439
P F + L + G ++ +P P I+W+KN I + PK R +G L
Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1569
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+I DS YT AIN G + C++ V+ A
Sbjct: 1570 KIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFA 1606
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/284 (20%), Positives = 102/284 (35%), Gaps = 42/284 (14%)
Query: 200 GKPKPQATWTHNGHALDSQRVSMRTGDQDS-ILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
G+P+P A WT +G A+ + D+ L I SDSG Y TV+
Sbjct: 26572 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--------- 26622
Query: 259 IDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
G SS L + + +TE QK + T Q V++
Sbjct: 26623 ------NSAGSVSSSCKLTI------------KAIKDTEAQKVSTQKTSEITPQKKAVVQ 26664
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
S+ I + S+ L A+ ++K+ + K + +
Sbjct: 26665 EEISQKALRSEEIKMSEAK----SQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 26720
Query: 379 SEAPSFTQPLADHTSTPGYSTQ--------LFCSVRASPKPKIIWMKNKMEIQGNPKYRA 430
++ ++ + H +STQ L + + W+ N +E+ + +YR
Sbjct: 26721 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 26780
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
TL I++ S D G+ TC I+ E V C+ ++ S
Sbjct: 26781 GVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDLTLS 26822
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 379 SEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGV 436
++AP+FTQPL G + + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
L I + +SG Y+ KA N G+A+ L VKA A
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102
Score = 43.5 bits (101), Expect = 4e-04
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 9/129 (6%)
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
S+S + T+E+A ++ I G I+ D P PL D S G L S+ +
Sbjct: 4408 SSSESGTEEVATVK---IQEAEGGLIKED---GPMIHTPLVDTVSEEGDIVHLTTSITNA 4461
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFD-SGVYTCKAINVLGEASVDC 467
+ + W + + K++ L +Q TL I K + D G Y C+A+N G+ +
Sbjct: 4462 KE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4519
Query: 468 RLEVKASAA 476
+L V AA
Sbjct: 4520 KLTVVKRAA 4528
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+F Q L T G +L V P P + + ++ EIQ + ++ E + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ P DSG Y+ A N +G A+ L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ PL D ++ G + C V + K+ W +I+ + +R + LEI
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ P D G YT A N +G+ S L ++ A
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQA 3391
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRAL-SEQGVCTLE 440
P F + L G +V P P + W K ++ + Y + + G T
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ P DSG+Y CKA N+LGE++ L V
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 54 APTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
AP S A P ++ P P + +S + V W P G + GY LE +
Sbjct: 18184 APLDSKAVIVQYPFKE-PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ WV ++ P+ T+ L G ++ +VSA + G G P+ + + R+ + P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18301
Score = 41.2 bits (95), Expect = 0.002
Identities = 67/326 (20%), Positives = 116/326 (35%), Gaps = 44/326 (13%)
Query: 156 PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL 215
P I + ++EAPKI ++ + Q G + ++ GKP P+ W NG +
Sbjct: 2016 PTFKPDKIELSPSMEAPKIF--ERIQSQTVGQ-GSDAHFRVRVVGKPDPECEWYKNGVKI 2072
Query: 216 DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRL 275
+ +D++ EL +R E A I + I G SS
Sbjct: 2073 ERSDRIYWYWPEDNVC-------------ELVIRDVTAEDSASIMVKAINIAGETSSHAF 2119
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
L V T EL + ++ D E + + +
Sbjct: 2120 LLVQAKQLI--------TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEG 2171
Query: 336 YSFRVFSE------NLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLA 389
+R+ S+ ++ + TS ++ ++ K +E E F + L
Sbjct: 2172 DKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVE---FVKELQ 2228
Query: 390 DHTSTPGYSTQLFCSVRASPKPKII---WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
D YS +L C V P+ I W N +E++ N KY S +G L ++ +
Sbjct: 2229 DIEVPESYSGELECIV----SPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTK 2284
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y+ V+ C+L++K
Sbjct: 2285 EDQGEYSF----VIDGKKTTCKLKMK 2306
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/285 (21%), Positives = 104/285 (36%), Gaps = 56/285 (19%)
Query: 202 PKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVID 260
P + W +G L + + + L I + + D G Y V AK ++
Sbjct: 2600 PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVE 2659
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF---TVL 317
+ I+K +++ L V T QD T L + + K QW VL
Sbjct: 2660 AVKIKK-----TLKNLTV---------TETQDAVFTVELTH----PNVKGVQWIKNGVVL 2701
Query: 318 ERYHPTTCTISDLIIGNSYSFRV-----FSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
E ++ G YS R+ E++ G H++ I KPK
Sbjct: 2702 ESNEKYAISVK----GTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPK- 2756
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D T+ + SV P + W +EI+ + K+R +S
Sbjct: 2757 -----------------DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVS 2798
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
E+ V L ++ SP D+G YT V+G+ ++C+ ++ H
Sbjct: 2799 ERKVHKLMLQNISPSDAGEYTA----VVGQ--LECKAKLFVETLH 2837
Score = 40.4 bits (93), Expect = 0.004
Identities = 19/61 (31%), Positives = 29/61 (47%)
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ W +++ + KY E GV L ++ + D G Y CK +N GE S L V
Sbjct: 25294 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353
Query: 472 K 472
K
Sbjct: 25354 K 25354
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/126 (24%), Positives = 44/126 (34%), Gaps = 6/126 (4%)
Query: 350 TSATVTKELAHIQKADIAAKPKGFIERDFSE----APSFTQPLADHTSTPGYSTQLFCSV 405
T T+E ++ D+ E AP F G S C V
Sbjct: 1000 TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV 1059
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+PKP + W K+ + + +Y+ + G C L I D+G YT N GE
Sbjct: 1060 GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGET 1119
Query: 464 SVDCRL 469
S L
Sbjct: 1120 SASASL 1125
Score = 40.0 bits (92), Expect = 0.005
Identities = 41/151 (27%), Positives = 63/151 (41%), Gaps = 11/151 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L L D++ SVT+ W+ P G + Y++E RE + +
Sbjct: 14561 DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEK-REATRKSYSTATTKCHKC 14619
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V L+ G ++ RV A + G G P +P+ + EAP P L I +
Sbjct: 14620 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV---KASEAPS--PPDSLNIMDITK- 14673
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
TV+L P KPK G+ +++QR
Sbjct: 14674 -STVSLAWP---KPKHDGGSKITGYVIEAQR 14700
Score = 39.3 bits (90), Expect = 0.008
Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR---VSMRTGDQDSILFIRSAQR 238
Q+ + G T + G P P+ +W +G + + V + D + L I + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 239 SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL 276
++SGRY L +A + ++LV + PP+ ++ L
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110
Score = 38.5 bits (88), Expect = 0.014
Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 26/144 (18%)
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSIL 231
P+ +P + + Y VGE V + P+P TW +G ++ GD D
Sbjct: 25385 PEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIKPGDNDK-- 25432
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT--- 288
+ SD G Y+LT+ + A ++ K G S C A L T
Sbjct: 25433 --KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS---------CKAKLTVTLHP 25481
Query: 289 PPQDTGNTELLGYMVQKADKKTGQ 312
PP D+ + ++ A+ + GQ
Sbjct: 25482 PPTDSTLRPMFKRLLANAECQEGQ 25505
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 1/97 (1%)
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE-QG 435
D + P F + LA+ G S V P P + W K+ + P + E
Sbjct: 25485 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 25544
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
L IR P D+G Y A N G S L+V+
Sbjct: 25545 YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Score = 37.7 bits (86), Expect = 0.023
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 4/80 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
GE+ G+P P TW G L S R + T S I S Q SD G Y +
Sbjct: 26270 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY--S 26327
Query: 248 VRVEDLEAKAVIDI-LVIEK 266
V VE+ E K + L I+K
Sbjct: 26328 VVVENSEGKQEAEFTLTIQK 26347
Score = 37.0 bits (84), Expect = 0.039
Identities = 35/150 (23%), Positives = 59/150 (39%), Gaps = 8/150 (5%)
Query: 333 GNSYSFRVF---SENLCGLSTSATVTK-ELAHI----QKADIAAKPKGFIERDFSEAPSF 384
G+SY + V S + + T+A+V +L H Q A+ K + EAP
Sbjct: 3432 GSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGEAPKI 3491
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
L D T G + Q C ++ + W +I+ + + + + L I
Sbjct: 3492 FLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNV 3551
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
D G+Y+C N GE + L V+ +
Sbjct: 3552 QLVDQGLYSCIVHNDCGERTTSAVLSVEGA 3581
Score = 36.6 bits (83), Expect = 0.051
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTC 325
PG P + V + + W P+ G + + GY ++ D + +W V + T
Sbjct: 10012 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10071
Query: 326 TIS----DLIIGNSYSFRVFSENLCGLSTSA 352
+S LI G+ Y FRV++ N G+ ++
Sbjct: 10072 GVSYKVTGLIEGSDYQFRVYAINAAGVGPAS 10102
Score = 36.6 bits (83), Expect = 0.051
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PP D P P + T ++ S+ V W P+ G + Y++E + W+ + +
Sbjct: 15349 PP--DPPKNPEVTT---ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 15403
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPA 157
+ + V L G ++ R+ A ++AG P+
Sbjct: 15404 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15436
Score = 35.8 bits (81), Expect = 0.088
Identities = 18/64 (28%), Positives = 30/64 (46%)
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P + W+ + ++ + R ++E G C+L+ DSG+ TC+A N G
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745
Query: 469 LEVK 472
L VK
Sbjct: 1746 LIVK 1749
Score = 35.8 bits (81), Expect = 0.088
Identities = 26/104 (25%), Positives = 43/104 (41%)
Query: 370 PKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR 429
P F P F + +++ + G L +V PKPKI W N + + + Y+
Sbjct: 3637 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3696
Query: 430 ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
+ + +L I D G YTC A N G+ L++ +
Sbjct: 3697 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3740
Score = 35.8 bits (81), Expect = 0.088
Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 3/134 (2%)
Query: 42 EQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGR 99
E + + +A P ++P A S +PS P + + + W PE G
Sbjct: 22904 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22963
Query: 100 LGLQGYVLELCREGASEWVPVSARPMMV-TQQTVRNLALGDKFLLRVSAVSSAGAGPPAM 158
+ Y+++ + + W V+ ++ T+ V +L G + RV+AV++AG P+
Sbjct: 22964 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 23023
Query: 159 LDQPIHIRENIEAP 172
I RE P
Sbjct: 23024 ASNFISCREPSYTP 23037
Score = 35.8 bits (81), Expect = 0.088
Identities = 54/291 (18%), Positives = 98/291 (33%), Gaps = 34/291 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + Q KP + W HNG L +S ++ L I DSG Y
Sbjct: 26083 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRA- 26141
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
+ G S LDV G + + +D ++
Sbjct: 26142 --------------VCTNYKGEASDYATLDVTGGDYTTYASQRRD-----------EEVP 26176
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS------ENLCGLSTSATVTKELAHI 361
+ T E Y ++ + + +S V S E+L SA+ + A +
Sbjct: 26177 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26236
Query: 362 QKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
++ + K + A T+P + T G S + C P P + W++
Sbjct: 26237 EEKSLEEKSTTRKIKTTLAARILTKPRS-MTVYEGESARFSCDTDGEPVPTVTWLRKGQV 26295
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + +++ + + T EI D G Y+ N G+ + L ++
Sbjct: 26296 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346
Score = 35.0 bits (79), Expect = 0.15
Identities = 37/142 (26%), Positives = 56/142 (39%), Gaps = 14/142 (9%)
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
WF + H T+ T+ G ++ + L +S KEL+ + +
Sbjct: 5301 WFKNDAKLH-TSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKV------ 5353
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+E D P FT L D T+ L C V S + W K+ EI +PKY +
Sbjct: 5354 -LEAD----PYFTVKLHDKTAVEKDEITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIKA 5406
Query: 433 EQGVCTLEIRKPSPFDSGVYTC 454
+ L+I+K D G Y C
Sbjct: 5407 DGLRRILKIKKADLKDKGEYVC 5428
Score = 35.0 bits (79), Expect = 0.15
Identities = 63/289 (21%), Positives = 114/289 (39%), Gaps = 40/289 (13%)
Query: 173 KIRVPRHLRQTYIRQVGETV-NLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSI 230
K+R+ L+ T +++ E V N ++ +G +A W N A+ DS + + D
Sbjct: 6334 KLRIVVPLKDTRVKEQQEVVFNCEVNTEGA---KAKWFRNEEAIFDSSKYIILQKDLVYT 6390
Query: 231 LFIRSAQRSDSGRYELTVRVEDLE-AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L IR A D Y +++ E K+ +++V E+ +R+++ P
Sbjct: 6391 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE-----DLRIVE-----------P 6434
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPT---TCTISDLIIGNSYSFRVFSENLC 346
+D ++ +KK+ ++ + R + T T ++ N S+RV
Sbjct: 6435 LKD----------IETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHM 6484
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS-FTQPLADHTSTPGYSTQLFCSV 405
E +I A + K E EAP+ F + L D T T + +F
Sbjct: 6485 LTIKDCGFPDEGEYIVTA---GQDKSVAELLIIEAPTEFVEHLEDQTVTE-FDDAVFSCQ 6540
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
+ K + W +N EI+ KY+ + + L I+ D Y C
Sbjct: 6541 LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 6589
Score = 34.7 bits (78), Expect = 0.20
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTC 454
G + + V P P+ W + +I + ++ + E G +L I +P DSG +T
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTV 1484
Query: 455 KAINVLGEASVDCRLEVKA 473
A N G +S+ L V+A
Sbjct: 1485 VAQNRAGRSSISVILTVEA 1503
Score = 34.7 bits (78), Expect = 0.20
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E FT+ LA+ + + +L C V + P ++IW K EI +Y L+E L
Sbjct: 6156 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 6214
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I+ D+G Y C+ L + D +++V AA
Sbjct: 6215 VIQNAHLEDAGNYNCR----LPSSRTDGKVKVHELAA 6247
Score = 34.3 bits (77), Expect = 0.26
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI--LFIRSAQRSDSGRY 244
GE+V L+ G P P TW + ++S + + Q I L IR A DSGR+
Sbjct: 911 GESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARLMIREAFAEDSGRF 967
Score = 34.3 bits (77), Expect = 0.26
Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P + + +VS SVT++WE P G + Y++E RE A T
Sbjct: 23231 DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK-REAAMRAFKTVTTKCSKT 23289
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ L G + RV + G G P + + E
Sbjct: 23290 LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 23328
Score = 33.9 bits (76), Expect = 0.33
Identities = 55/255 (21%), Positives = 94/255 (36%), Gaps = 49/255 (19%)
Query: 208 WTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
WT NG + RVS R +L I+ D G Y +T + K+V ++L+IE
Sbjct: 6461 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQD----KSVAELLIIEA 6516
Query: 267 PGP------PSSIRLLD--VWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
P ++ D V+ C + + + N G +++ K + +
Sbjct: 6517 PTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRN----GREIKEGKKYKFEKDGSIH 6572
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
R C + D E CG+ D ++ + F+E
Sbjct: 6573 RLIIKDCRLDDEC-----------EYACGVE---------------DRKSRARLFVE--- 6603
Query: 379 SEAP-SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
E P +P D PG +F + K ++ W++N M + K++ +SE +
Sbjct: 6604 -EIPVEIIRPPQDILEAPGADV-VFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIH 6661
Query: 438 TLEIRKPSPFDSGVY 452
L+I P D G Y
Sbjct: 6662 RLQICDIKPRDQGEY 6676
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 4/77 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G+T + G+P P+ W H+G + D + D L I A SDSG E
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG--EW 1482
Query: 247 TVRVEDLEAKAVIDILV 263
TV ++ ++ I +++
Sbjct: 1483 TVVAQNRAGRSSISVIL 1499
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G + + C V P+PK+ W N I+ + ++R + G+ L+I +D+G
Sbjct: 1809 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1867
Query: 456 AINVLGEASVDCRLEVK 472
A N G +LE++
Sbjct: 1868 AENPEGVIEHKVKLEIQ 1884
Score = 30.4 bits (67), Expect = 3.7
Identities = 63/326 (19%), Positives = 120/326 (36%), Gaps = 54/326 (16%)
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T ++L++ D +RV A+ + +L+ + + Q Y +
Sbjct: 5681 TFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKL------------QDYTGVEKD 5728
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
V LQ P W +G + S+ ++ + +L ++ A +SD G+Y
Sbjct: 5729 EVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCG 5787
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG-YMVQKAD- 307
+ K I+ I+ P S+ +++ + + N +L G ++Q D
Sbjct: 5788 TDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDC 5847
Query: 308 --KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ-KA 364
K+ G+ I L++ N C L + V + A+++ A
Sbjct: 5848 EIKEEGK--------------IHSLVLHN-----------CRLDQTGGVDFQAANVKSSA 5882
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
+ KP+ +PL D T T G + C + P ++K K +++
Sbjct: 5883 HLRVKPR---------VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGK-KLEP 5932
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSG 450
+ K SE V TL +R D+G
Sbjct: 5933 SDKVVPRSEGKVHTLTLRDVKLEDAG 5958
Score = 30.4 bits (67), Expect = 3.7
Identities = 34/160 (21%), Positives = 60/160 (37%), Gaps = 10/160 (6%)
Query: 13 SPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDV-- 70
S ET E EV+ SE+ E +PK T + + + +V
Sbjct: 9128 SKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHV 9187
Query: 71 -----PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSAR 123
PS P L + D+ + S ++W+ P G + YV++ +EW V+
Sbjct: 9188 EVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT-N 9246
Query: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
+ + + L ++ RV AV+ G D+ +
Sbjct: 9247 TAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 9286
Score = 30.0 bits (66), Expect = 4.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F +PL D + C + + K+ W K+ EI+ KY +S+ V L I K
Sbjct: 6071 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6129
Query: 444 PSPFDSGVYTCK 455
D Y+C+
Sbjct: 6130 CLLDDEAEYSCE 6141
Score = 29.3 bits (64), Expect = 8.2
Identities = 20/86 (23%), Positives = 33/86 (38%), Gaps = 4/86 (4%)
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
PL D G L C V + W N +I+ + + +A+ + L I +
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y ++G +C L V+
Sbjct: 2464 SDEGPYKL----IVGRVETNCNLSVE 2485
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 155 bits (392), Expect = 8e-38
Identities = 92/303 (30%), Positives = 156/303 (51%), Gaps = 15/303 (4%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
PA A + + +P PP + +TL DV+ +SV++SWE PE G + GY++E+
Sbjct: 15664 PAETAESVKASERPLPPGK--------ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15715
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
+G+ +W + + VT+ T+ L G+++ RVSA + G P L P+ ++ +
Sbjct: 15716 QTKGSDKWATCAT--VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 15773
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQD 228
P ++ L T+ GE + + +PF G+P P TW + L + RV+ + + +
Sbjct: 15774 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 15830
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQW 287
S+L I+ A R D G Y + + EA ++++V++KPGPP+ +++ +V + L W
Sbjct: 15831 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 15890
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G + + Y+V+K D T W V TT L G Y FR+ +EN G
Sbjct: 15891 GPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYG 15950
Query: 348 LST 350
ST
Sbjct: 15951 KST 15953
Score = 155 bits (392), Expect = 8e-38
Identities = 92/291 (31%), Positives = 146/291 (50%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A + + PS P +TL DVS +S ++ WE PE G + GYV+E+ +G +W V
Sbjct: 17831 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17890
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ V V L+ G ++ RV A + G P +L P+ ++ P +++P +
Sbjct: 17891 AESK--VCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN- 17947
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
TY Q GE + ++IP G+P+P +W +G L + RV++ ++L I+ +
Sbjct: 17948 --TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKD 18005
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTEL 298
D G+Y +T A + ++V+EKPGPP +R +V + W PP TG ++
Sbjct: 18006 DFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQI 18065
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+V+K D T W V TT I+ L G Y FR+F+EN G S
Sbjct: 18066 SNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 18116
Score = 155 bits (392), Expect = 8e-38
Identities = 96/325 (29%), Positives = 162/325 (49%), Gaps = 9/325 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR-PMMV 127
D P P + + D + SS+T+ W P G + GYV+E+ + EW VS + +
Sbjct: 20793 DPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRT 20852
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ V NL G + RVSAV+ AG G P +++P+ ++ +EAP+I + LR + I +
Sbjct: 20853 TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAK 20912
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRSDSGRYEL 246
GE V + IPF+G+P P TW + L S R S+ D S+L I R+D+G+Y L
Sbjct: 20913 AGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYIL 20972
Query: 247 TVRVEDLEAK-AVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
T+ E K + + + V++ P +++ V L W PP G + ++ Y+++K
Sbjct: 20973 TIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEK 21032
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
D W V + T+ + DL + FRV +EN G+ T+ ++ A+
Sbjct: 21033 RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP---VKAAE 21089
Query: 366 IAAKPKGFIERDFSEAP---SFTQP 387
+ A + +D ++ S+T+P
Sbjct: 21090 VPAPIRDLSMKDSTKTSVILSWTKP 21114
Score = 154 bits (389), Expect = 2e-37
Identities = 121/445 (27%), Positives = 189/445 (42%), Gaps = 28/445 (6%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V KP A P A +P+PP LT D + SSV + WEPP + G +
Sbjct: 6901 VGKPSAATPFVKVADPIERPSPPVN--------LTSSDQTQSSVQLKWEPPLKDGGSPIL 6952
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
GY++E C EG W+ + + + V L G+K+L RVSA + AG P+ + P+
Sbjct: 6953 GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPL 7012
Query: 164 HIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSM 222
+ P + + + V + + +P G P+P ATW L++ RV M
Sbjct: 7013 TADDAFVEPTMDLSAFKDGLEVI-VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKM 7071
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
+T + L I ++RSD G Y L + ID+ VI +P P ++ D+ +
Sbjct: 7072 KTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDS 7131
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP D G + L GY+V+K + W V++ T+ DL+ G Y F+V +
Sbjct: 7132 VHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCA 7191
Query: 343 ENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
N CG A V + + A + P+ RD + F D G S
Sbjct: 7192 RNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL--TWDPPKNDGGSRIKG 7249
Query: 403 CSVRASPKPKIIWM-------KNKMEIQGNP-------KYRALSEQGVCTLEIRKPSPFD 448
V P+ W+ + KME+ G + +AL+ QG + +P+
Sbjct: 7250 YIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS--KPSRPTEEI 7307
Query: 449 SGVYTCKAINVLGEASVDCRLEVKA 473
V T +A + + + L VKA
Sbjct: 7308 QAVDTQEAPEIFLDVKLLAGLTVKA 7332
Score = 154 bits (388), Expect = 2e-37
Identities = 82/278 (29%), Positives = 141/278 (50%), Gaps = 1/278 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P ++ + D S ++V++ W P G + + GY++E+C+ +W V+A + T+
Sbjct: 21882 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRY 21941
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV +L G+++ RVSA++ AG G + I + + AP++ + + +QT++ + G
Sbjct: 21942 TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGA 22001
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
++ L I +QG+P P A W+ L S R + T D S L + + R+D+G+Y LTV
Sbjct: 22002 SIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVEN 22060
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
+ V++ PGPP I DV +A L W P G + Y+V+K +
Sbjct: 22061 NSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASR 22120
Query: 311 GQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
W + E+ ++DL G Y FRV + N G+
Sbjct: 22121 RSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGV 22158
Score = 153 bits (386), Expect = 4e-37
Identities = 88/291 (30%), Positives = 151/291 (51%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE P P +TL DV+ ++ T+ WE PE G + GYV+E+ +G+ +W
Sbjct: 18915 TEPVKVSEP-PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-- 18971
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + T+ L G++++ RV+AV+ G P L P+ R+ P + +P H
Sbjct: 18972 TCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH- 19030
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
T+ + E + + +PF+G+P+ W +G L ++ RV++ + + L I+ A +
Sbjct: 19031 --TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKE 19088
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
D G YEL V I I+V+++PGPP IR+ +V + + W PP+ G ++
Sbjct: 19089 DVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQIS 19148
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
Y+V+K + + W V + T+ I L G+ Y FRV +EN G S+
Sbjct: 19149 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSS 19199
Score = 152 bits (384), Expect = 6e-37
Identities = 89/283 (31%), Positives = 147/283 (51%), Gaps = 7/283 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
+VP P +T+DDV+ +SV++SW PE G + Y++E+ + + +W + +
Sbjct: 16757 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSL-- 16814
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
Q + NL G+++L RV AV+ G P L PI ++ + P ++ +Y QV
Sbjct: 16815 QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF---SSYSVQV 16871
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + +++P G+PKP TWT +G L + R+++ + L I+ + D G+Y +T
Sbjct: 16872 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 16931
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
V + A I+I+ ++KP PP ++ DV + L W PP TG ++ Y+VQK
Sbjct: 16932 VANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKR 16991
Query: 307 DKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D T W V TT ++ L G Y FR+F+EN G S
Sbjct: 16992 DTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17034
Score = 149 bits (375), Expect = 7e-36
Identities = 90/292 (30%), Positives = 144/292 (49%), Gaps = 2/292 (0%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A +VP P L + DV+ S+VT++WE P G L GYVLE C+ G W+ V
Sbjct: 23253 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 23312
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
V + TV +L G+++L R+ A + G P + +++ P I +
Sbjct: 23313 VTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 23372
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++T G V L IP G+P P A+W G L +S+RV++ T + + L IR
Sbjct: 23373 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 23432
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G Y L ++ I +++++KPGPP+ I++ ++ + + W PP+ G L
Sbjct: 23433 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 23492
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
GY+V++ D W V E +T + L GN Y FRV + N G+ +
Sbjct: 23493 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 23544
Score = 145 bits (367), Expect = 6e-35
Identities = 109/371 (29%), Positives = 175/371 (47%), Gaps = 16/371 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE PS P L + D++ S+V+++W P+ G + GYV+E R+G+ +W +
Sbjct: 14584 TEPVKASE-APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14642
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + VRNL G+++ +V AV+SAG P +P+ ++E P++ +
Sbjct: 14643 TT--VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTMLPELDLRGIY 14699
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++ I + G+ + ++IP G+PKP TW L +QRV+ T +IL I RS
Sbjct: 14700 QKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRS 14759
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
DSG Y LT R E VI I V + PGPP+ I+ +V W PP++ G +
Sbjct: 14760 DSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 14819
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y+V+ + W + TT + L G Y FRV ++N G+ TSA +
Sbjct: 14820 SNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIV 14879
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ +D S S+ +PL+D G S L V + I+W
Sbjct: 14880 ANYPFKVPGPPGTPQVTAVTKD-SMTISWHEPLSD-----GGSPILGYHVERKERNGILW 14933
Query: 416 MK-NKMEIQGN 425
+K + GN
Sbjct: 14934 QTVSKALVPGN 14944
Score = 145 bits (366), Expect = 8e-35
Identities = 94/331 (28%), Positives = 158/331 (47%), Gaps = 19/331 (5%)
Query: 49 APAPQAP---TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
AP+P +P T KP PP P +L D S SS++++W P G + GY
Sbjct: 15367 APSPTSPFYKACDTVFKPGPPGN-----PRVL---DTSRSSISIAWNKPIYDGGSEITGY 15418
Query: 106 VLELCREGASEW-VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E+ EW + + T T+ L ++ +R+ A++S G G PA++
Sbjct: 15419 MVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 15478
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMR 223
+ + P+I + LR+ + T+ L +P +G+P P+ W +G +LD + S+
Sbjct: 15479 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 15536
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ ++L + + R DSG+Y LTV A +++ V++ PGPP +++ +V +
Sbjct: 15537 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15596
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L W PP G +++ Y+V+K + + TV H T+ + L G SY FRV +E
Sbjct: 15597 TLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAE 15656
Query: 344 NLCGLSTSATVTKELAHIQKADIAAKPKGFI 374
N G+ A E A KA P G I
Sbjct: 15657 NEYGIGLPA----ETAESVKASERPLPPGKI 15683
Score = 144 bits (362), Expect = 2e-34
Identities = 86/282 (30%), Positives = 140/282 (49%), Gaps = 4/282 (1%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P L + +V+ ++VT++W PP+ G + YVLE G ++ V+ ++ +
Sbjct: 10344 VPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 10403
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV+ L GD + RVSAV+ G G P+ +PI ++ + P + + R +VG
Sbjct: 10404 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL--DFRDKLTIRVG 10461
Query: 190 ETVNLQIPFQGKPKPQATW-THNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
E L + GKPKP+ +W L+ R ++T L A+RSDSG+Y + V
Sbjct: 10462 EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV 10521
Query: 249 RVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
K + V+++PGPP + +V + W PP D G +++ Y+++K +
Sbjct: 10522 ENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKE 10581
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
W V TTC +S L+ G Y FR+ +ENL G+S
Sbjct: 10582 VGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGIS 10623
Score = 144 bits (362), Expect = 2e-34
Identities = 84/305 (27%), Positives = 146/305 (47%), Gaps = 10/305 (3%)
Query: 54 APTASTATKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A A + KP+ PS+ + P P + D + +SV+++W PE G + GY
Sbjct: 23636 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 23695
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165
++E+ + EW + P + + T+ +L G ++ RV A ++ G G PA + + +
Sbjct: 23696 LIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23755
Query: 166 RENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG 225
E +E P + ++ + G + L IP +GKP P WT G + S+R + T
Sbjct: 23756 TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI-SKRAMIATS 23814
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
+ + L I+ A R DSG Y+L + + + I + VI P P + D+ +
Sbjct: 23815 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR 23874
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
+ W PP D G ++LGY++++ + W+T+ R T+ + L Y FRV +EN
Sbjct: 23875 VSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 23934
Query: 345 LCGLS 349
G+S
Sbjct: 23935 QFGIS 23939
Score = 140 bits (354), Expect = 2e-33
Identities = 81/280 (28%), Positives = 142/280 (50%), Gaps = 2/280 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P + D +++S+ ++W+PP+ G ++GY++E C G+ +WV P+ T+
Sbjct: 7215 VPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETK 7273
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
V L G + RV A++ GA P+ + I + EAP+I + L + G
Sbjct: 7274 MEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAG 7333
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
+ L GKP+P+ TWT L +R+++ + S + I ++RSD+G Y +
Sbjct: 7334 TKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEA 7393
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
A AV+++ V++KPGPP++ + DV + L W PP+D G +++ Y+V++
Sbjct: 7394 VNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRAT 7453
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ W + T + LI Y FRV +EN+ G+
Sbjct: 7454 DSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGV 7493
Score = 140 bits (354), Expect = 2e-33
Identities = 91/313 (29%), Positives = 146/313 (46%), Gaps = 9/313 (2%)
Query: 54 APTASTATKPAPPSEDV-------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYV 106
A A+ K +PPS+ P P + + D SS+++ + WEPP G + GY
Sbjct: 8606 AENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYF 8665
Query: 107 LELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR 166
++ G +EW + + + V Q TV+ + G + LRVSAV++AG GPP QP+ +
Sbjct: 8666 VDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVA 8724
Query: 167 ENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGD 226
E E P + + ++ G+T+ + G+P P WT LD RV +
Sbjct: 8725 EPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVG 8784
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
S L I+ A R D GRY +T A + V + PGP ++ + L
Sbjct: 8785 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8844
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W+ P+D G +E+ G+++++ D K W +E + C I+ L+ G Y FRV ++N
Sbjct: 8845 WSDPEDDGGSEITGFIIERKDAKMHTWRQPIET-ERSKCDITGLLEGQEYKFRVIAKNKF 8903
Query: 347 GLSTSATVTKELA 359
G + LA
Sbjct: 8904 GCGPPVEIGPILA 8916
Score = 140 bits (353), Expect = 3e-33
Identities = 88/305 (28%), Positives = 147/305 (48%), Gaps = 7/305 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
TK + PS P L + +S SV+++W PE G + YV+E +G WV
Sbjct: 19993 TKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC 20052
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ T V L ++ RV A + AG P L P+ I+E +E P+I +
Sbjct: 20053 AVAKS--THHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFP 20110
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRS 239
T + G + + IP GKP P+ T + +G L + R + ++ + ++ + +
Sbjct: 20111 SHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA 20170
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+GRYE+T KA I+I+V+++PGPP+ + + D+ + L+W PP+ G +++
Sbjct: 20171 DAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQV 20230
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y++ K + T W V T + L G Y FR+ +EN G+S SA VT
Sbjct: 20231 TNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVT 20290
Query: 356 KELAH 360
+L +
Sbjct: 20291 VKLPY 20295
Score = 139 bits (351), Expect = 4e-33
Identities = 86/300 (28%), Positives = 149/300 (49%), Gaps = 6/300 (2%)
Query: 61 TKPAPPSED---VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEW 117
T P +ED +PS P + D +++T++W P G + GY +E + ++W
Sbjct: 19699 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 19758
Query: 118 VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVP 177
S + + T+ T+ L G +++ RV +V+ GA P+ P +E E P +
Sbjct: 19759 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 19817
Query: 178 RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQ 237
+R+T I + G + + +PF+G+P P W+ L + R + T D + L I +A
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENAN 19876
Query: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
R+DSG+Y LT++ A + + V++ PGPP++I + DV +A L W P++ G
Sbjct: 19877 RNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAP 19936
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
+ Y ++K + W +V + + +++L G Y FRV EN G+ A TKE
Sbjct: 19937 VKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKE 19995
Score = 138 bits (347), Expect = 1e-32
Identities = 87/299 (29%), Positives = 144/299 (48%), Gaps = 14/299 (4%)
Query: 61 TKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+ PSE D P P+ L +++ +VT+ W PE G + Y++E
Sbjct: 14970 SKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDL 15026
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEA 171
W+ + ++ + TV L + RV A ++AGA PP+ I R+++EA
Sbjct: 15027 PNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEA 15086
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSI 230
PKI+V + T I + GE L+ G+P P W+ +G L+ + ++ ++ D +
Sbjct: 15087 PKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN 15146
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTP 289
L + + R DSG Y LT AK + ++ V+++PGPP + + +V L W P
Sbjct: 15147 LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15206
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P D G ++ Y+VQK + W V T ++ L+ GN Y FRV + N G+
Sbjct: 15207 PLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15265
Score = 138 bits (347), Expect = 1e-32
Identities = 86/314 (27%), Positives = 145/314 (46%), Gaps = 10/314 (3%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V +P P+ P PPS + D S SSV+++W P G ++
Sbjct: 18612 VGEPSEPSVFYRACDALYPPGPPSNP--------KVTDTSRSSVSLAWSKPIYDGGAPVK 18663
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
GYV+E+ A EW + + +Q TV L ++ R+ A++S G G PA L
Sbjct: 18664 GYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 18723
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM 222
+ +E IE P+I + LR+ + + T+ L + +G+P+P+ W + + R +
Sbjct: 18724 VVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKW-EKAEGILTDRAQI 18782
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
++L I + R DSGRY LT+ A +++ V++ P P ++ + +V +
Sbjct: 18783 EVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDS 18842
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP G ++ Y+V+K + + T+ TT I +L G SY FRV +
Sbjct: 18843 VTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 18902
Query: 343 ENLCGLSTSATVTK 356
N G+ A T+
Sbjct: 18903 SNEYGIGLPAETTE 18916
Score = 137 bits (344), Expect = 3e-32
Identities = 85/320 (26%), Positives = 153/320 (47%), Gaps = 10/320 (3%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P + S K A PS P + D + S +++W P G L + GYV+E +
Sbjct: 14285 PSEASDSVLMKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 14341
Query: 112 EGASEWVP-VSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G W+ + + +TQ V +L +K+ R+SA++ AG G PA++ + I E
Sbjct: 14342 VGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREM 14400
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
AP + LR+T + + G ++ + +P +G+P P+ TWT + L + R ++ + ++
Sbjct: 14401 APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN-RANIENTESFTL 14459
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I R D+G++ +T+ + +++ V++ PGP ++R D+ + L W P
Sbjct: 14460 LIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLP 14519
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
G + + Y+V+K + + T + H T ++ L G Y FRV +EN G+
Sbjct: 14520 LIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14579
Query: 351 SATVTKELAHIQKADIAAKP 370
T+ + KA A P
Sbjct: 14580 PTETTEPV----KASEAPSP 14595
Score = 135 bits (340), Expect = 8e-32
Identities = 87/319 (27%), Positives = 146/319 (45%), Gaps = 11/319 (3%)
Query: 63 PAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P+PPS+ V PS P+ D + +SV ++W+PP G + GY++E + G
Sbjct: 10725 PSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGD 10784
Query: 115 SEWVPVSARPMMV--TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
EW + P T+ V L G + RV AV++AG PA + +P+ +++ +E P
Sbjct: 10785 EEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPP 10844
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
++ + ++ + +VG+T+ L +G P P+ TW + + + S L
Sbjct: 10845 ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT-KARIDVTPVGSKLE 10903
Query: 233 IRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
IR+A D G Y LTV + +LV++KPGPP + + ++ + L W P D
Sbjct: 10904 IRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLD 10963
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
G + + Y+V++ D + QW + + L GN Y FRV +EN G
Sbjct: 10964 DGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFV 11023
Query: 353 TVTKELAHIQKADIAAKPK 371
K + + PK
Sbjct: 11024 ETPKPIKALDPLHPPGPPK 11042
Score = 135 bits (340), Expect = 8e-32
Identities = 83/299 (27%), Positives = 153/299 (51%), Gaps = 2/299 (0%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ++ A + P P + D + SSV++SW P G + GY++E+ R
Sbjct: 13198 PGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKR 13257
Query: 112 EGASEWVPVSA-RPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
+ WV + + + T+ V L ++ RV AV+ G P+ + + ++ +
Sbjct: 13258 ADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 13317
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRTGDQDS 229
P+ + LR+T I + G T+ L +P +G+P P+ TW+ N + D + +++ D D+
Sbjct: 13318 PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDT 13377
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L + + D+G+Y LT+ + + I + V++ PGPP ++ + ++ +A + W P
Sbjct: 13378 FLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEP 13437
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P G + ++ Y+VQK D + W TV T+ +++L G SY FRVF+EN G+
Sbjct: 13438 PIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGI 13496
Score = 134 bits (338), Expect = 1e-31
Identities = 85/299 (28%), Positives = 151/299 (50%), Gaps = 10/299 (3%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P PT + + P P PS PL L + D + ++W+PPE+ G + GY +E+C
Sbjct: 7897 PSEPTEILSIEDPTSP----PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMC 7952
Query: 111 REGASEWVPVSARPMMVTQQTVRNLALGDK-FLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
G +W+ V++RP+ + V + DK ++LRV AV++ G P+ + + + ++
Sbjct: 7953 PVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPD 8012
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQD 228
P I + H I GE +++ +PF+ P P +W +G + S R++M+
Sbjct: 8013 CKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS 8069
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+ L + + R+D+G Y +T+ + A A I++ VI PGP I+ D+ + L W
Sbjct: 8070 AHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWE 8129
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G T +L Y++++ + + V+ + + T+ DLI Y FRV + N G
Sbjct: 8130 PPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8188
Score = 134 bits (338), Expect = 1e-31
Identities = 86/307 (28%), Positives = 140/307 (45%), Gaps = 11/307 (3%)
Query: 46 KPQAPAPQAPTAS-TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQG 104
K + P PT TA P P P P ++ DV+ S+V++ W P+ G + G
Sbjct: 12799 KAGSSPPSKPTEYVTARMPVDP----PGKPEVI---DVTKSTVSLIWARPKHDGGSKIIG 12851
Query: 105 YVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK--FLLRVSAVSSAGAGPPAMLDQP 162
Y +E C+ +WV + P + Q+ L +K + R A ++ PP+ P
Sbjct: 12852 YFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12911
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVS 221
+ I P+I + ++ + G V L GKP P +W +G L ++ +
Sbjct: 12912 VTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK 12971
Query: 222 MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGC 281
M L + S R DSG Y +T A I + V++KPGPP+S+++ ++
Sbjct: 12972 MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSD 13031
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
A L W PP + G +E+ Y+V K + W V T+C++ LI G+ Y FR+
Sbjct: 13032 RAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRIC 13091
Query: 342 SENLCGL 348
+EN G+
Sbjct: 13092 AENKYGV 13098
Score = 134 bits (337), Expect = 2e-31
Identities = 111/426 (26%), Positives = 182/426 (42%), Gaps = 23/426 (5%)
Query: 48 QAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVL 107
+ P + P A P P P P L DV + V++ W P+R G + GY++
Sbjct: 11019 RGPFVETPKPIKALDPLHP----PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11074
Query: 108 ELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E EG +W+ + + + V L G + RV A + G G P PI +E
Sbjct: 11075 EYQEEGTQDWIKF--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 11131
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSMRTGD 226
+ P + + L + + + G TV +G P P A WT +G + + + ++ T +
Sbjct: 11132 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11191
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
S+L I++ R D+G Y++TV + + V++ PGPP+ I +LDV + +
Sbjct: 11192 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11251
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W PP+D G + ++ Y+V+K D + W V T I L G Y FRV +EN
Sbjct: 11252 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 11311
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE---APSFTQPLADHTS-TPGY---- 397
G+ T +A K + P + D +E S+T P +D S GY
Sbjct: 11312 IGVGPPLDSTPTVAK-HKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 11370
Query: 398 --STQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
T + V +P + + + ++R +E + KPSP + C+
Sbjct: 11371 REVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 11427
Query: 456 AINVLG 461
I G
Sbjct: 11428 PIKPPG 11433
Score = 133 bits (335), Expect = 3e-31
Identities = 99/424 (23%), Positives = 187/424 (44%), Gaps = 20/424 (4%)
Query: 41 EEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRL 100
E +V A P+ +T A P P + D + +S+T++W P G
Sbjct: 17518 EFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGS 17577
Query: 101 GLQGYVLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAML 159
+ GYV+E+C+ EW V+ + + VT+ + L ++ +RV A++ G G +
Sbjct: 17578 EILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV 17637
Query: 160 DQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
+ + +EAP++ + LR+ + + G + + IPF+G+P P+ TW+ + +
Sbjct: 17638 PGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDK 17696
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
V + G + L I + R+D+G+Y L + A + + V++ PGPP ++ + +V
Sbjct: 17697 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17756
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR 339
+A L W PP G ++ Y++ K + + V + T+ + +L G Y FR
Sbjct: 17757 KDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFR 17816
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
V +EN G+ V E KA P G + L D + T ++
Sbjct: 17817 VMAENEFGVG----VPVETVDAVKAAEPPSPPGKV------------TLTDVSQTS--AS 17858
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
++ +++ +M+ +G K+ ++E VC + S + KA N
Sbjct: 17859 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNE 17918
Query: 460 LGEA 463
G++
Sbjct: 17919 KGKS 17922
Score = 132 bits (332), Expect = 7e-31
Identities = 74/289 (25%), Positives = 139/289 (48%), Gaps = 11/289 (3%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT-- 128
P P + D + SS+++ W+PP + G ++GY++E+ EG ++W V+ ++T
Sbjct: 9333 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9392
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ V NL K+ RV AV+ AG P+ I + E P++ + + + +
Sbjct: 9393 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9452
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR---------VSMRTGDQDSILFIRSAQRS 239
G + + +G+P P+++W +G A + + + T + S++ I +RS
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
+G+Y +T + + + A + V++ PGPP +++ D+ + L W P D G +
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIK 9572
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
GY+++K W V TT + DL+ Y FRV +EN G+
Sbjct: 9573 GYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 9621
Score = 132 bits (332), Expect = 7e-31
Identities = 84/317 (26%), Positives = 143/317 (45%), Gaps = 3/317 (0%)
Query: 57 ASTATKPAPPSEDV-PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
AS + PA + + P P + D + SS + W PP + G + GY++E EG
Sbjct: 10034 ASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKE 10093
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIR 175
EW + + T+ V L G + RV AV+ AG G P + I +++ + +P ++
Sbjct: 10094 EWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQ 10153
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRS 235
+ +R + G + + GKP P TW N L Q ++ T S + I++
Sbjct: 10154 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL-PQEATIETTAISSSMVIKN 10212
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTG 294
QRS G Y L + E E K I + V++ PGP + L ++ + L W P+D G
Sbjct: 10213 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 10272
Query: 295 NTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATV 354
+ + Y+++K + W V T+ LI G +Y FR+ +EN G+
Sbjct: 10273 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 10332
Query: 355 TKELAHIQKADIAAKPK 371
++ L + + +P+
Sbjct: 10333 SEALVIREPITVPERPE 10349
Score = 131 bits (329), Expect = 2e-30
Identities = 90/314 (28%), Positives = 138/314 (43%), Gaps = 14/314 (4%)
Query: 52 PQAPTASTATKPAPPSEDV--PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P PT KP S+ + P P L + +++ +S T++W PP R G + GY+
Sbjct: 12408 PGVPT--DVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSY 12465
Query: 110 CREG--ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E A W S + V L G K+ RV+A ++ G P + +E
Sbjct: 12466 REEEQPADRWTEYSV--VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE 12523
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHN-GHALDSQRVSMRTGD 226
+ PKI +P + + G+ + ++ GKP P W + S +++ D
Sbjct: 12524 QLLPPKILMPEQITI----KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 12579
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
SIL I+ R DSG Y LT I ++V++ PGPP + D+ +L
Sbjct: 12580 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 12639
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W P + G + + Y+V+K D G W T L T+C + LI G Y FRV +EN
Sbjct: 12640 SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12699
Query: 346 CGLSTSATVTKELA 359
G+S T K +A
Sbjct: 12700 FGISEPLTSPKMVA 12713
Score = 131 bits (329), Expect = 2e-30
Identities = 83/309 (26%), Positives = 146/309 (47%), Gaps = 12/309 (3%)
Query: 46 KPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
+P P+ KP PP+ P ++ D++ SSV +SW P G +QGY
Sbjct: 16449 EPSPPSAYQKACDPIYKPGPPNN-----PKVI---DITRSSVFLSWSKPIYDGGCEIQGY 16500
Query: 106 VLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E C EW + + T V L ++ R+ A++ AG G A + PI
Sbjct: 16501 IVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPII 16560
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMR 223
+ E +EAP I + LR+ + G ++ L +P +G+P P+ W +G D+ + +
Sbjct: 16561 VEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT 16620
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ +L + R DSG+Y LT+ A + + V++ P PP ++++ ++ +
Sbjct: 16621 SSFTSLVL--DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16678
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
++ W PP G +++ Y+V+K + + V+ H + I L G SY FRV +E
Sbjct: 16679 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16738
Query: 344 NLCGLSTSA 352
N G+ A
Sbjct: 16739 NEYGIGLPA 16747
Score = 130 bits (326), Expect = 3e-30
Identities = 82/290 (28%), Positives = 144/290 (49%), Gaps = 7/290 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+ A + P + L + VS SS ++ W+ P G + GYV++ E ++W V
Sbjct: 13502 TRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKWQRV 13560
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ Q + ++L G ++ RVSA + G G P+ + + R+++ AP + +
Sbjct: 13561 MKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLP 13616
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRS 239
Y+ + L+IP +GKP P +W L + RVS+ + ++ L + Q+S
Sbjct: 13617 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13676
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G+Y +T++ + I I V+ KPG P+ I+ +V L+W PP+D G +E+
Sbjct: 13677 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13736
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Y+++K D +W T TT ++ L G Y+FRV +EN G+
Sbjct: 13737 TNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13786
Score = 129 bits (325), Expect = 4e-30
Identities = 91/314 (28%), Positives = 152/314 (48%), Gaps = 15/314 (4%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P P+ K P P P P + D + S+T+ W P G + GYV+E+
Sbjct: 12109 PSLPSRPVVAKDPIEP----PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMR 12164
Query: 111 REGASE-----WVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ A W +A +V ++ TV +L ++ RV A + G G PA L + I
Sbjct: 12165 PKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 12224
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
+E +E P+I + +R+ I + G + L +G+P P+ TW G ++ +
Sbjct: 12225 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL 12284
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
D + L I ++ R DSG+Y LT+ E +++ V++ PGP S +++ DV +
Sbjct: 12285 VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCH 12344
Query: 285 LQWTPPQDTGNTELLGYMVQK--ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
+ W PP++ G +++ Y+V+K AD+KT W TV T+ +++L+ GN Y FRV +
Sbjct: 12345 VSWAPPENDGGSQVTHYIVEKREADRKT--WSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12402
Query: 343 ENLCGLSTSATVTK 356
N G V K
Sbjct: 12403 VNEYGPGVPTDVPK 12416
Score = 124 bits (310), Expect = 2e-28
Identities = 79/279 (28%), Positives = 135/279 (48%), Gaps = 5/279 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR-PMMVTQ 129
PSAP ++ D + S++++W P G + GYVLE+ + +W V + T+
Sbjct: 22973 PSAPRVV---DTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 23029
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV +L +G K+ RV+AV+ G + I E IE P + + L++T + G
Sbjct: 23030 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAG 23089
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
++ L + G+P P TW+ G L S R + T + S+L + R D+G+Y +
Sbjct: 23090 ASLRLMVSVSGRPPPVITWSKQGIDLAS-RAIIDTTESYSLLIVDKVNRYDAGKYTIEAE 23148
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ + A + + V + PGP S+++ +V + + W P G + Y+V+K +
Sbjct: 23149 NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAA 23208
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ TV + T IS L+ G Y FRV EN+ G+
Sbjct: 23209 MRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23247
Score = 123 bits (309), Expect = 3e-28
Identities = 83/281 (29%), Positives = 129/281 (45%), Gaps = 4/281 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P+ P L + D S SS ++W P+ G + GY+LE+ ++G+ WV +
Sbjct: 22174 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTF-- 22231
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV L ++ RV A + AG P + I+E P + Q + G
Sbjct: 22232 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGS 22291
Query: 191 TVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ +P G+P P+ TW L ++ RVS+ T + L ++ + R DSGRY LT+
Sbjct: 22292 PFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLE 22351
Query: 250 VEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ ++VI +PGP + I + V + L W P+D G TE+ Y+V+K +
Sbjct: 22352 NTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRES 22411
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
T W V T ++ L YSFRV SEN G+S
Sbjct: 22412 GTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVS 22452
Score = 123 bits (308), Expect = 4e-28
Identities = 90/304 (29%), Positives = 137/304 (45%), Gaps = 10/304 (3%)
Query: 54 APTASTATKPAPPSE-----DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A+ KP+ PSE D P + + D+S +SV++SW+ P G + GY++E
Sbjct: 20374 AENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE 20433
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRE 167
W S + TQ + L ++ RV A ++ G+ P+ + PI +
Sbjct: 20434 RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCID 20493
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM--RTG 225
+ P I +P + + G +V L+ GKP P W + L + + T
Sbjct: 20494 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTT 20553
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
D SIL I+ A R +SG YEL +R A A I + +++KPGPP I V
Sbjct: 20554 DLASIL-IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKIT 20612
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L W PP D G ++ Y+V+K + W V E T + +I GN Y FRV + N
Sbjct: 20613 LLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVN 20672
Query: 345 LCGL 348
G+
Sbjct: 20673 KYGI 20676
Score = 122 bits (307), Expect = 5e-28
Identities = 110/421 (26%), Positives = 172/421 (40%), Gaps = 35/421 (8%)
Query: 67 SEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMM 126
S + P PL DD+ SV VSW PP G + GY+LE + W + +R +
Sbjct: 23855 SPNSPEGPL--EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VR 23911
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK--IRVPRHLRQT- 183
T V+ L ++ RVSA + G P ++P+ + + P+ P L T
Sbjct: 23912 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTK 23971
Query: 184 ------YIRQVGETVNLQIPFQGKPKPQAT--WT-HNGHALDSQRVSMRTGDQDSILFIR 234
+ R + + + + K +T W HN + + ++ D+ R
Sbjct: 23972 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 24031
Query: 235 SAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++D G E + E + K D KP P + +L + + LQW P+ G
Sbjct: 24032 IIAQNDVGLSETSPASEPVVCKDPFD-----KPSQPGELEILSISKDSVTLQWEKPECDG 24086
Query: 295 NTELLGYMVQKADKKTGQWF-TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
E+LGY V+ W + ER TI L+ Y FRVF+EN GLS
Sbjct: 24087 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24146
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKI 413
+ K + + EAP + + D T+ G + QL C + P P I
Sbjct: 24147 TAMSI----KTKLTS----------GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 24192
Query: 414 IWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
W + E+ + KY+ S+ TL + D GVYTC A N +GE +L ++A
Sbjct: 24193 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24252
Query: 474 S 474
+
Sbjct: 24253 T 24253
Score = 120 bits (300), Expect = 4e-27
Identities = 72/270 (26%), Positives = 126/270 (46%), Gaps = 3/270 (1%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V + +T+ W P G + GY++E W+ S ++ TQ TV L ++
Sbjct: 17160 VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRY 17219
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AGA P+ PI ++ +E P+I + R T + GET L+ G
Sbjct: 17220 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 17279
Query: 201 KPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W ++ S R ++ D ++L ++ A R D G+Y L +
Sbjct: 17280 KPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPV 17339
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP +++ V +L W+PP G +++ Y+V+K + W V
Sbjct: 17340 NVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVAS 17399
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ ++ L+ GN Y FR+ + N G+
Sbjct: 17400 EVVTNSLKVTKLLEGNEYVFRIMAVNKYGV 17429
Score = 117 bits (293), Expect = 2e-26
Identities = 77/312 (24%), Positives = 140/312 (44%), Gaps = 13/312 (4%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V+ +SVT+ W+ P G + GY++E W+ S ++ T V L ++
Sbjct: 16078 VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 16137
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AG P+ I R+ ++ P+I + + T + GE+ + G
Sbjct: 16138 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16197
Query: 201 KPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W L ++ R+ +++ D + L ++ A R DSG Y L + E +
Sbjct: 16198 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16257
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP + + V L W PP G ++++ Y+V++ + W V
Sbjct: 16258 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 16317
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
+C ++ L+ GN Y+FR+ + N G+ ++ + AK F+ D
Sbjct: 16318 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP---------LESEPVVAK-NPFVVPDA 16367
Query: 379 SEAPSFTQPLAD 390
+AP T D
Sbjct: 16368 PKAPEVTTVTKD 16379
Score = 116 bits (291), Expect = 4e-26
Identities = 77/322 (23%), Positives = 147/322 (45%), Gaps = 13/322 (4%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+P S+ + P P+ L D S + + W P G + GYV+E +
Sbjct: 11414 SKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKP 11473
Query: 113 GASEWVPVSARPMMVTQQTVR--NLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G ++W ++ + ++ Q R L G+++ R+ A + G G P L + + ++ +
Sbjct: 11474 GTAQWNRIN-KDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILH 11532
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
P++ + R +VG+T+ + +G+P+P TWT G L +RV +
Sbjct: 11533 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV 11592
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L I+ A R+D G+Y ++ + A+ + V+++PGP ++++ +V N + W
Sbjct: 11593 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWEN 11652
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
P D G +E+ ++V+ W V ++L+ N Y FRV +EN G+
Sbjct: 11653 PLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGVG 11711
Query: 350 TSATVTKELAHIQKADIAAKPK 371
+ + I D +P+
Sbjct: 11712 PTIETKTPILAINPIDRPGEPE 11733
Score = 116 bits (290), Expect = 5e-26
Identities = 83/297 (27%), Positives = 140/297 (47%), Gaps = 14/297 (4%)
Query: 62 KPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
KP+ PSE D P P ++ +++ +SVT+ W P+ G L GY++E
Sbjct: 13888 KPSLPSEPVVALDPIDPPGKPEVI---NITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLP 13944
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAP 172
+ W+ + + TV +L G K+ R+ A ++AGA P+ + I ++ EAP
Sbjct: 13945 SKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14004
Query: 173 KIRVPRHLRQTYIRQVGETVNLQ-IPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSI 230
I + ++ + G+T+ L I GKP P+++W+ G + ++ T S+
Sbjct: 14005 TIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 14064
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I+ A R D+G Y +T + + V++ PGPP + + +V A L WTPP
Sbjct: 14065 LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP 14124
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
+ G + + Y+++K + W V E + LI GN Y FRV + N G
Sbjct: 14125 LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14181
Score = 115 bits (288), Expect = 9e-26
Identities = 75/309 (24%), Positives = 133/309 (43%), Gaps = 36/309 (11%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P+ + + + ++ ++T++W+PP G + GY++E +G W + + +
Sbjct: 8208 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8267
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T + L G ++ RV A ++AG P+ P + I+APK+ LR + + G+
Sbjct: 8268 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSLEVKRGD 8323
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG------------------------- 225
+ L G P P TW + + + + + R
Sbjct: 8324 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 8383
Query: 226 -----DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWG 280
+S L +R + R D G Y + V + AKA + V++ PGPP + D+
Sbjct: 8384 IDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRK 8443
Query: 281 CNAALQWTPPQDTGNTELLGYMVQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSF 338
+ +W PP D G +E++ Y ++K D K +W V +++ LI G Y F
Sbjct: 8444 TSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLF 8503
Query: 339 RVFSENLCG 347
RV +EN G
Sbjct: 8504 RVRAENRFG 8512
Score = 115 bits (287), Expect = 1e-25
Identities = 87/321 (27%), Positives = 145/321 (45%), Gaps = 17/321 (5%)
Query: 54 APTASTATKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A ++ + P+ PS+ D P P + DV+ ++T+ W PP R G + GY
Sbjct: 21461 AENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGY 21517
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIH 164
+E R+G WV + + Q TV L+ GD++ R+ A ++ G PP+ I
Sbjct: 21518 SIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIM 21576
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
R+ P + I + GE++ ++ QG+P P+ TW +G ++ +R++M
Sbjct: 21577 TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNMEI 21635
Query: 225 GDQ--DSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGC 281
D + LF+R A R G Y + + AKA I + V + PG IR ++ G
Sbjct: 21636 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 21695
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
L W P + G + Y+++K + W + ++ + T LI GN Y FRV
Sbjct: 21696 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 21755
Query: 342 SENLCGLSTSATVTKELAHIQ 362
+ N G+ +A IQ
Sbjct: 21756 AVNKFGVGRPLDSDPVVAQIQ 21776
Score = 114 bits (284), Expect = 3e-25
Identities = 81/305 (26%), Positives = 136/305 (44%), Gaps = 7/305 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L + D + V + W P+ G Y +E +G+ +W V + T
Sbjct: 11727 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11786
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V + RV + G ++ + ++E+++ P + + L +
Sbjct: 11787 HYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVV-VKEDLQKPVLDLK--LSGVLTVKA 11843
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD---SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
G+T+ L+ +GKP P+ WT + A D S RV + T S + A+RSD G+Y
Sbjct: 11844 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11903
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
+T A + V++KPGP +++++DV + W PP+D G E+ Y+++K
Sbjct: 11904 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEK 11963
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ K W T T++ LI GN Y FRV +EN G + T +K + K D
Sbjct: 11964 CETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG-TGPPTESKPVIAKTKYD 12022
Query: 366 IAAKP 370
+P
Sbjct: 12023 KPGRP 12027
Score = 114 bits (284), Expect = 3e-25
Identities = 73/298 (24%), Positives = 141/298 (47%), Gaps = 12/298 (4%)
Query: 58 STATKPAPPSE--DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
S + +P P + D P P + +++ SV++ W P G + GY++E
Sbjct: 19301 SKSCEPVPARDPCDPPGQP---EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDG 19357
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKI 174
W+ + + T V L ++ RV A ++A + P+ PI +++++E P++
Sbjct: 19358 RWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRV 19417
Query: 175 RVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFI 233
+ R + + GE + + G+P P +W +G ++ + R + + D ++L +
Sbjct: 19418 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19477
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA---ALQWTPP 290
+ R D+G+Y LT++ ++ V++KPGPP+ L++ G A +L W P
Sbjct: 19478 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGP--LEINGLTAEKCSLSWGRP 19535
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Q+ G ++ Y+V+K + W T+C ++ L+ GN Y FRV N G+
Sbjct: 19536 QEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 19593
Score = 112 bits (279), Expect = 1e-24
Identities = 72/284 (25%), Positives = 129/284 (45%), Gaps = 7/284 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ ++VT+ W+ P G + GY++E W+ S ++ T
Sbjct: 18232 DPPGRPEAIV---ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLET 18288
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L ++ RV A ++AG P+ I R+ I+AP + + +
Sbjct: 18289 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18348
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALD--SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
GET L+ +GKP P W+ +G L+ + R+ +++ Q + L ++ R+D G+Y
Sbjct: 18349 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L + I + V+++PGPP +++ V L W PP G + Y+++
Sbjct: 18409 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 18468
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
K + W V ++ L+ GN Y FRV + N G+
Sbjct: 18469 KRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18512
Score = 107 bits (267), Expect = 2e-23
Identities = 103/376 (27%), Positives = 164/376 (43%), Gaps = 17/376 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P +E VP+ L++ D + +SV +SW P+ G + YV+E R+G E
Sbjct: 21082 TEPVKAAE-VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE--RKGKGEQTWS 21138
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
A + V L RV A + G P + PI ++E I P++ +
Sbjct: 21139 HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIP 21197
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++G V+L++P++GKPKP +W +G L +S+ V + L I++A++
Sbjct: 21198 GAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKE 21257
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS----IRLLDVWGCNAALQWTPPQDTGN 295
G+Y TV +++ + + I VI GPPS IR ++ + L W P+D G
Sbjct: 21258 HGGKY--TVILDNAVCRIAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21314
Query: 296 TELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
E+ Y ++K + W V TT + +L+ Y FRV +EN G+S +
Sbjct: 21315 GEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSS 21374
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+A Q K I S+ S T D G S V + I+W
Sbjct: 21375 IIVAKHQFRIPGPPGKPVIYNVTSDGMSLTW---DAPVYDGGSEVTGFHVEKKERNSILW 21431
Query: 416 MK-NKMEIQGNPKYRA 430
K N I G +YRA
Sbjct: 21432 QKVNTSPISGR-EYRA 21446
Score = 107 bits (266), Expect = 3e-23
Identities = 88/337 (26%), Positives = 145/337 (43%), Gaps = 14/337 (4%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P++P LT + + S++T+ W+ P G +QGY++E R ++ V+ R T
Sbjct: 8923 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 8982
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVG 189
V NL + RV AV+ G P+ L + I+++ P I++ +R I+ + G
Sbjct: 8983 LVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAG 9041
Query: 190 ETVNLQIPFQGKPKPQATWTHN-------GHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
E V++ G P P+ W+ N AL + + + + L I A R D G
Sbjct: 9042 EPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKG 9101
Query: 243 RYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYM 302
Y +T + + V ++P PP ++ + D+ + L W P D G +E+ Y+
Sbjct: 9102 TYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 9161
Query: 303 VQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAH 360
+ K D +K +W V I LI Y FRV + N G+S K +
Sbjct: 9162 IDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 9221
Query: 361 --IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTP 395
+ KPK S S+T PL D+ +P
Sbjct: 9222 DPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSP 9257
Score = 107 bits (266), Expect = 3e-23
Identities = 81/313 (25%), Positives = 135/313 (43%), Gaps = 22/313 (7%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P + +TA P P P P+ L + ++ ++V +SW+PP+ G + Y++E
Sbjct: 9623 PPVETIQRTTARDPIYP----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC 9678
Query: 110 CREGAS-----EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ W + R + Q TV +L G ++ RV AV++AG P+ P
Sbjct: 9679 LAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCD 9738
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATW--------THNGHALD 216
+ P I L++ + G VN+ +G P P TW + L
Sbjct: 9739 CQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY 9794
Query: 217 SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRL 275
V+ D L I ++RSD+G Y +T A + + V+ +PGPP I+
Sbjct: 9795 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKF 9854
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
V L W PP+D G +++ Y+++K + W V T TI L+ G+
Sbjct: 9855 ESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHE 9914
Query: 336 YSFRVFSENLCGL 348
Y FR+ ++N G+
Sbjct: 9915 YVFRIMAQNKYGI 9927
Score = 105 bits (263), Expect = 7e-23
Identities = 89/333 (26%), Positives = 143/333 (42%), Gaps = 11/333 (3%)
Query: 23 KVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLD 80
KVP E +V E Q A AS A++P A D P P +
Sbjct: 22520 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP---EVT 22576
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLE---LCREGASEWVPVSARPMMVTQQTVRNLAL 137
DV+ S+V++ W P G + GY++E + G W+ + + TV L+
Sbjct: 22577 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 22636
Query: 138 GDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVGETVNLQ 195
GD + RV A ++AG + P+ R+ PK + L + + G + L
Sbjct: 22637 GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLD 22696
Query: 196 IPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLE 254
GKP+P+ WT LD ++VS++ + + I+ RSDSG+Y LTV+
Sbjct: 22697 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 22756
Query: 255 AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF 314
+ + V++ PGP + + V L W+ PQ+ G E+ Y+V++ + W
Sbjct: 22757 KAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV 22816
Query: 315 TVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
V + ++ LI N Y FRV + N G
Sbjct: 22817 IVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG 22849
Score = 102 bits (254), Expect = 8e-22
Identities = 105/421 (24%), Positives = 177/421 (42%), Gaps = 43/421 (10%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P LT+ V+ T++W P+ G + Y++E WV V ++
Sbjct: 22767 DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS 22826
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
R L ++++ RV AV+ G G P +PI R + P P + + +V
Sbjct: 22827 YVVTR-LIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPS---PPGIPE----EV 22877
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQ--------RVSMRTGDQDSILFIRSAQRSD 240
G I KP+ + + +D + RV+ D+ L + S
Sbjct: 22878 GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGC 22937
Query: 241 SGRYELTV-----RVEDLEAKAVIDILVIE-KPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++ +T E EA I PGPPS+ R++D + +L WT P G
Sbjct: 22938 DYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDG 22997
Query: 295 NTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
T+++GY+++ +K T QW+ V T T+ DL +G YSFRV + N+ G+S +
Sbjct: 22998 GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYS 23057
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
E+ +++ +I D A + + T G S +L SV P P
Sbjct: 23058 ESIAEIEPVERIEIP---------DLELADDLKKTV---TIRAGASLRLMVSVSGRPPPV 23105
Query: 413 IIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
I W K +++ RA+ + + L + K + +D+G YT +A N G+ S ++
Sbjct: 23106 ITWSKQGIDLAS----RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23161
Query: 471 V 471
V
Sbjct: 23162 V 23162
Score = 100 bits (249), Expect = 3e-21
Identities = 105/423 (24%), Positives = 170/423 (40%), Gaps = 42/423 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DVSS TV W+PPE G +Q Y+LE C W SA ++
Sbjct: 11923 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSAT-VLTP 11981
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
TV L G++++ RV A + G GPP +P+ + + P P + T + +
Sbjct: 11982 GTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDKPGRPDPPEV--TKVSKE 12038
Query: 189 GETVNLQIP------------FQGKPKPQATWTH-NGHALDSQRVSMRTGDQDSILFIRS 235
TV P + K K W N A+ +R+ ++ ++L
Sbjct: 12039 EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQ-----NLLPDHE 12093
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
Q E+ + L ++ V+ IE PGPP++ R++D + L W P G
Sbjct: 12094 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGG 12153
Query: 296 TELLGYMVQK----ADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++GY+V+ AD + + + T++ L Y FRV ++N G+
Sbjct: 12154 APIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGI 12213
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
A + + A KPK +E + + + L G +LF VR
Sbjct: 12214 GRPAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGR 12261
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P PK+ W K ++ L + + L I + DSG Y+ +N GE +V
Sbjct: 12262 PAPKVTWRKVGIDNVVRKGQVDLVDT-MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12320
Query: 469 LEV 471
+ V
Sbjct: 12321 VRV 12323
Score = 100 bits (248), Expect = 4e-21
Identities = 80/321 (24%), Positives = 140/321 (43%), Gaps = 21/321 (6%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ST D P P T+ DV +SV ++W PE G ++ YV+E+ +
Sbjct: 7593 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLK 7652
Query: 112 EGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEA 171
G EWV V A + TQ + L G ++ RV AV+ AG P+ P+ RE +
Sbjct: 7653 TGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7711
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKP------------QATWTHNGHALDSQR 219
P PR L I + + +P + P + W + +
Sbjct: 7712 PS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTK 7769
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
++ + S+ R A + G+ + T +ED +V+ PGPP ++ ++DV
Sbjct: 7770 CTVTPLTEGSLYVFRVAAENAIGQSDYT-EIED----SVLAKDTFTTPGPPYALAVVDVT 7824
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSF 338
+ L+W PP++ G + Y+++K ++ +W + P ++D+I G F
Sbjct: 7825 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 7884
Query: 339 RVFSENLCGLSTSATVTKELA 359
+V +EN G+ + T+ L+
Sbjct: 7885 QVRAENEAGVGHPSEPTEILS 7905
Score = 97.1 bits (240), Expect = 3e-20
Identities = 80/302 (26%), Positives = 132/302 (43%), Gaps = 37/302 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L D++ +VT++W P+ G + GY +E +WV + P+ T
Sbjct: 7509 DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDT 7568
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V+ L K+ RV A + AG G P+ +PI I++ I+ P + ++ V
Sbjct: 7569 TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-----GKPTVKDV 7623
Query: 189 GETVNLQIPFQGKPKPQATWT---HNGHA-LDSQRVSM-RTGDQDSILFIRSAQRS---- 239
G+T + WT H+G A ++S + M +TG + + +
Sbjct: 7624 GKT-----------SVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLL 7672
Query: 240 ----DSGRYELTVRV-----EDLEAKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQW 287
+ Y VR E ++ +L EK P PP + ++++ A L+W
Sbjct: 7673 PGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKW 7732
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
T P+ G + + Y+V+K D + W TV T CT++ L G+ Y FRV +EN G
Sbjct: 7733 TVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIG 7792
Query: 348 LS 349
S
Sbjct: 7793 QS 7794
Score = 96.7 bits (239), Expect = 4e-20
Identities = 97/445 (21%), Positives = 172/445 (38%), Gaps = 86/445 (19%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP+ V + D++ SVT+ WEPP+ G + Y+L + W VS
Sbjct: 20197 RPGPPTGPV-------VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS 20249
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A + T V L G+++ R+ A + G I ++I++
Sbjct: 20250 AT-VARTMMKVMKLTTGEEYQFRIKAENRFG------------ISDHIDSA--------- 20287
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHN-----------------GHALDSQRVSMRT 224
V +++P+ P W N G A+ + M+
Sbjct: 20288 ---------CVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMK- 20337
Query: 225 GDQDSILFIRSAQR------------SDSGRYELTVRVEDLEAKAVID-----ILVIEKP 267
D++SIL+ ++ + S YE V E+ +L I+
Sbjct: 20338 -DRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC 20396
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCT 326
PP ++R+ D+ + +L W P G +++ GY+V++ D G+W T
Sbjct: 20397 EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFI 20456
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
IS L + Y FRVF+ N G + + ++ + I D P + +++E +
Sbjct: 20457 ISGLTQNSQYEFRVFARNAVG--SISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRA 20514
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
G S +L + P P I W K+ E+Q N + + ++ I+
Sbjct: 20515 ---------GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADR 20565
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
+SG Y K N +G AS R+++
Sbjct: 20566 LNSGCYELKLRNAMGSASATIRVQI 20590
Score = 96.3 bits (238), Expect = 5e-20
Identities = 95/412 (23%), Positives = 163/412 (39%), Gaps = 42/412 (10%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D+P P + D+VSS VT SW+PPE G + + YV+E+ + ++ WV ++ +
Sbjct: 14785 DIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRT 14844
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPA-----MLDQPIHIRENIEAPKIRVPRHLRQ 182
T + R L G ++ RV A + G GP + + P + P++
Sbjct: 14845 TYKATR-LTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQV-------- 14895
Query: 183 TYIRQVGETVNLQIPFQGKPKPQATW-----THNGHALDSQRVSMRTGDQDSILFIRSAQ 237
T + + T++ P P + NG + ++ G+ +S+
Sbjct: 14896 TAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGN-----IFKSSG 14950
Query: 238 RSDSGRYELTVRVEDLEAKAVID-----ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+D YE V E++ K+ +L ++ PP L++ L+W P+
Sbjct: 14951 LTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEY 15010
Query: 293 TGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
TG ++ Y+V+K D G+W T+S L +Y FRV ++N G +
Sbjct: 15011 TGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISP 15070
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ + I D PK ++ F + G + +L V P P
Sbjct: 15071 PSEPSDA--ITCRDDVEAPKIKVDVKFKDTVILKA---------GEAFRLEADVSGRPPP 15119
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ W K+ E++G K L + + DSG YT A N G A
Sbjct: 15120 TMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 15171
Score = 94.4 bits (233), Expect = 2e-19
Identities = 96/427 (22%), Positives = 163/427 (38%), Gaps = 50/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ V +D+V++ S+T+SW PP+ G + Y++E + W VS
Sbjct: 15868 KPGPPTGPVK-------MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15920
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGP-----PAMLDQPIHIRENIEAPKIRV 176
A T + R L G ++ R++A + G P + P + P + +
Sbjct: 15921 ATVARTTIKACR-LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 15979
Query: 177 PRHLRQTYIRQVGETVN------LQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
R + Q E ++ + + K + W Q TG ++ +
Sbjct: 15980 SS--RDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16037
Query: 231 LFIRSAQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAAL 285
YE V E++ + V + V P PP + V + L
Sbjct: 16038 ------------EYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTL 16085
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSEN 344
QW P G +++ GY+V+K + G+W T ++ L+ + Y FRV + N
Sbjct: 16086 QWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARN 16145
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G+ + + + I D P+ S P + + H G S ++
Sbjct: 16146 AAGVFSEPS--ESTGAITARDEVDPPR------ISMDPKYKDTIVVHA---GESFKVDAD 16194
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ P P I W+K E+ + S +L ++ DSG Y KA NV GE S
Sbjct: 16195 IYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERS 16254
Query: 465 VDCRLEV 471
V ++V
Sbjct: 16255 VTVNVKV 16261
Score = 90.5 bits (223), Expect = 3e-18
Identities = 95/411 (23%), Positives = 162/411 (39%), Gaps = 38/411 (9%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
DVP P + + DV+ +T+SW+PP+ G + Y++E W VS+
Sbjct: 11230 DVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK- 11288
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ + +L G +++ RV A + G GPP LD + ++ +P P T I +
Sbjct: 11289 TKLKIPHLQKGCEYVFRVRAENKIGVGPP--LDSTPTVAKHKFSPP-SPPGKPVVTDITE 11345
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
TV+ +P P + + + V + + F R + YE
Sbjct: 11346 NAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYEFR 11404
Query: 248 VRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
V E+L + + I+ PGPP + +L D A L WT P G + +L
Sbjct: 11405 VFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPIL 11464
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCT--ISDLIIGNSYSFRVFSENLCGLS-----TSA 352
GY+V+ T QW + + C + LI GN Y FR+ + N+ G +
Sbjct: 11465 GYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAES 11524
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
+ K++ H + ++ + I T G + ++ V+ P+P
Sbjct: 11525 VIAKDILHPPEVELDVTCRDVI-----------------TVRVGQTIRILARVKGRPEPD 11567
Query: 413 IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
I W K + + + + L+I++ D G Y A N G A
Sbjct: 11568 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 11618
Score = 87.4 bits (215), Expect = 3e-17
Identities = 96/411 (23%), Positives = 161/411 (39%), Gaps = 48/411 (11%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
+++ +T+ W+ P G + Y++E W + + T L G++
Sbjct: 21691 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNE 21749
Query: 141 FLLRVSAVSSAGAGPPAMLDQPI-HIRENI-EAPKIRVPRHLRQTYIRQV-------GET 191
+ RVSAV+ G G P D + I+ + +AP I P ++ I G +
Sbjct: 21750 YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGS 21809
Query: 192 VNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVE 251
Q + + K W + S+R T + + L ++ YE V E
Sbjct: 21810 EIQQYILERREKKSTRWVK----VISKRPISETRFKVTGL-------TEGNEYEFHVMAE 21858
Query: 252 DLEA---KAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
+ + I L+ + PGPP+ +++ D +L+W+ P G E++GY++
Sbjct: 21859 NAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYII 21918
Query: 304 QKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ 362
+ G W V E T T++DL G Y FRV + N G S VT I+
Sbjct: 21919 EMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIK 21975
Query: 363 KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI 422
D P+ I+ +F + H G S +LF + + P P +W K
Sbjct: 21976 AVDRLTAPELDIDANFKQT---------HVVRAGASIRLFIAYQGRPTPTAVWSKP---- 22022
Query: 423 QGNPKYRA--LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
N RA + TL + + D+G YT N G S+ ++V
Sbjct: 22023 DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 22073
Score = 86.7 bits (213), Expect = 4e-17
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 4/180 (2%)
Query: 180 LRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQR 238
L++ Y VG T+ L + + G+P P TW H L +S+ +++ + + L +++ QR
Sbjct: 24262 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 24321
Query: 239 -SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA-LQWTPPQDTGNT 296
+ +G+Y++ + A++D+ + +KP P+ +++ N+A + W PP D G +
Sbjct: 24322 KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGS 24381
Query: 297 ELLGYMVQKADKKTG-QWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+ Y+V+K + K G +W V TTC I +L Y FRV ++N G+S V+
Sbjct: 24382 WITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVS 24441
Score = 86.3 bits (212), Expect = 6e-17
Identities = 51/201 (25%), Positives = 95/201 (47%), Gaps = 6/201 (2%)
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
APKI+ Q + VG+ + + +P+ PK +A W L ++ + T +Q S
Sbjct: 6627 APKIKTAD---QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSF 6682
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
+ A++ D GRY++ ++ + +A+ I++ VI+ PGP ++ + + + +L W P
Sbjct: 6683 RILE-AKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEP 6741
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGN-SYSFRVFSENLCGLS 349
G ++++GY+V++ D K W +R T++ L G Y FRV + N G
Sbjct: 6742 LTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTG 6801
Query: 350 TSATVTKELAHIQKADIAAKP 370
+ K D+ P
Sbjct: 6802 EPVETDNPVEARSKYDVPGPP 6822
Score = 86.3 bits (212), Expect = 6e-17
Identities = 96/417 (23%), Positives = 171/417 (41%), Gaps = 60/417 (14%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P+ P+ D+V++ ++T+ W PP+ G + Y+LE ++WV ++ T
Sbjct: 13706 IPTGPI--KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTF 13763
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
+ R L G ++ RVSA + G G + +PI R + P P ++ V
Sbjct: 13764 RVTR-LHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVS 13821
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR-YELTV 248
T PK G+ L+ + +++S+L+ R+ + R +++T
Sbjct: 13822 LTWT-------DPKKTGGSPITGYHLEFK-------ERNSLLWKRANKTPIRMRDFKVTG 13867
Query: 249 RVEDLEAK---AVIDILVIEKPG-------------PPSSIRLLDVWGCNAALQWTPPQD 292
E LE + I++ + KP PP ++++ + L WT P+
Sbjct: 13868 LTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKY 13927
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTS 351
G +L GY+V+K D + W P T++DL+ G Y FR+ ++N G ++
Sbjct: 13928 DGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISA 13987
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQL-------FCS 404
+ + E I +D EAP+ + D T G + + S
Sbjct: 13988 PSESTET--------------IICKDEYEAPTI---VLDPTIKDGLTIKAGDTIVLNAIS 14030
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P PK W K +I+ + + S L I+ + D+G YT A N G
Sbjct: 14031 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087
Score = 85.9 bits (211), Expect = 7e-17
Identities = 105/431 (24%), Positives = 166/431 (38%), Gaps = 52/431 (12%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T KP PP V DDVS+ S+T+SW PP G + Y+++ + W
Sbjct: 16947 TLDKPDPPKGPVK-------FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWD 16999
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
VSA T + V L G ++ R+ A + G A+ PI + + P P
Sbjct: 17000 VVSATVARTTLK-VTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPG--PPG 17055
Query: 179 HLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIR---- 234
T I + + P P G+ L+ + +++SIL+ +
Sbjct: 17056 TPFATAISKDSMVIQWHEPVNNGGSPVI-----GYHLERK-------ERNSILWTKVNKT 17103
Query: 235 -------SAQRSDSG-RYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGC 281
AQ + G YE V E++ +A + V P PP + + V
Sbjct: 17104 IIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRN 17163
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRV 340
LQWT P G + + GY+V+K D G+W T T+S L Y FRV
Sbjct: 17164 EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRV 17223
Query: 341 FSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
++N G + + + I AK + + R S P F + + G + +
Sbjct: 17224 IAKNAAGAISKPSDS-------TGPITAKDEVELPR-ISMDPKFRDTIVVNA---GETFR 17272
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L V P P I W++ EI+ + + + L ++ D G Y +A NV
Sbjct: 17273 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 17332
Query: 461 GEASVDCRLEV 471
G S ++V
Sbjct: 17333 GSKSFPVNVKV 17343
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/199 (29%), Positives = 95/199 (47%), Gaps = 11/199 (5%)
Query: 169 IEAP-KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTHNGHALDSQR--VSMR 223
+E P KI +P+ L GE V+++IPF GKP P TW +D+ +
Sbjct: 24647 VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIV 24706
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T S++F +R D+G Y + + + +++ V + P PP +++ DV +
Sbjct: 24707 TRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSV 24766
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L WT P G +++ Y+V+K +W V + T T+ +L SY FRV +E
Sbjct: 24767 NLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAE 24825
Query: 344 NLCGLS-----TSATVTKE 357
N GLS + T+TKE
Sbjct: 24826 NKFGLSKPSEPSEPTITKE 24844
Score = 85.1 bits (209), Expect = 1e-16
Identities = 98/427 (22%), Positives = 161/427 (37%), Gaps = 48/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + D+V+ + +SW+PP G + Y++E G W+PV+
Sbjct: 10539 RPGPPVGPV-------SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 10591
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + V L G ++ R+ A + G P + D + ++ P P
Sbjct: 10592 SASAKTTCK-VSKLLEGKDYIFRIHAENLYGISDPLVSDS-MKAKDRFRVPD--APDQPI 10647
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSILFIRSAQRSD 240
T + + V P G KP + S+R + T D R +
Sbjct: 10648 VTEVTKDSALVTWNKPHDGG-KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLE 10706
Query: 241 SGRYELTVRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+YE V E+ +K V I KP PP + +D + L W PP+
Sbjct: 10707 GCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRH 10766
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT-----ISDLIIGNSYSFRVFSENLCG 347
G +++LGY+V+ +W + P +C ++ L G +Y FRV + N G
Sbjct: 10767 DGGSKILGYIVEYQKVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAG 10824
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCS 404
S A V P+ + +D E P + G + +L
Sbjct: 10825 ESDPAHV---------------PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAI 10869
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
++ P PK+ W K + K R LEIR + D G+Y+ N G +
Sbjct: 10870 IKGVPFPKVTWKKEDRDAP--TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKT 10927
Query: 465 VDCRLEV 471
V ++ V
Sbjct: 10928 VSVKVLV 10934
Score = 84.7 bits (208), Expect = 2e-16
Identities = 101/423 (23%), Positives = 164/423 (38%), Gaps = 52/423 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP L + + V+++WE P G + GYV+E WV + R
Sbjct: 6716 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 6774
Query: 129 QQTVRNLALGD-KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L G ++L RVSA + G G P D P+ R + P P ++ T + +
Sbjct: 6775 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITDVNR 6832
Query: 188 VGETVNLQIP------------FQGKPKPQATW----THNGHALDSQRVSMRTGDQDSIL 231
G ++ + P + + K W T L + + G + S
Sbjct: 6833 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFR 6892
Query: 232 FIRSAQRSDSGRYELT---VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+R+ R G+ V+V D IE+P PP ++ D + L+W
Sbjct: 6893 -VRAQNRIGVGKPSAATPFVKVAD----------PIERPSPPVNLTSSDQTQSSVQLKWE 6941
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSFRVFSENLCG 347
PP G + +LGY++++ ++ W + P T ++ L GN Y +RV +EN G
Sbjct: 6942 PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG 7001
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+S + + L AD A F+E + +F L P T L S
Sbjct: 7002 VSDPSEILGPLT----ADDA-----FVEPTM-DLSAFKDGL--EVIVPNPITILVPST-G 7048
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN----VLGEA 463
P+P W ++ + + + L I D G+YT K N + GE
Sbjct: 7049 YPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEI 7108
Query: 464 SVD 466
V+
Sbjct: 7109 DVN 7111
Score = 83.6 bits (205), Expect = 4e-16
Identities = 97/430 (22%), Positives = 166/430 (38%), Gaps = 69/430 (16%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + V++ T++W+PP + G + Y++E W V
Sbjct: 16264 RPGPPEGPV-------VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVD 16316
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A ++ + V L G+++ R+ AV+ G G P + +P+ + P P+
Sbjct: 16317 ANVQTLSCK-VTKLLEGNEYTFRIMAVNKYGVGEP-LESEPVVAKNPFVVPD--APKAPE 16372
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQR--- 238
T + T + I +P G+ L+ + D++ I + R +R
Sbjct: 16373 VTTV-----TKDSMIVVWERPASDGGSEILGYVLEKR-------DKEGIRWTRCHKRLIG 16420
Query: 239 ---------SDSGRYELTVRVEDLEA----------KAVIDILVIEKPGPPSSIRLLDVW 279
++ YE V E+ + D I KPGPP++ +++D+
Sbjct: 16421 ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDIT 16478
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW--FTVLERYHPTTCTISDLIIGNSYS 337
+ L W+ P G E+ GY+V+K D G+W T + T + L+ + Y+
Sbjct: 16479 RSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYN 16538
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADH---TST 394
FR+ + N G+ A V P I + EAP L
Sbjct: 16539 FRICAINKAGVGEHADV---------------PGPIIVEEKLEAPDIDLDLELRKIINIR 16583
Query: 395 PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
G S +LF ++ P P++ W K EI+ S +L + + +DSG YT
Sbjct: 16584 AGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTL 16641
Query: 455 KAINVLGEAS 464
N G S
Sbjct: 16642 TLENSSGTKS 16651
Score = 82.8 bits (203), Expect = 6e-16
Identities = 88/406 (21%), Positives = 157/406 (38%), Gaps = 29/406 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + +VS+ T++W PP G ++ Y+LE W VS +
Sbjct: 14099 DVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSC 14157
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ L G++++ RVSAV+ G G P +P+ + + P P + + +
Sbjct: 14158 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPG--PPEKPEVSNVTKN 14214
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
TV+ + P + S R S L + + YE V
Sbjct: 14215 TATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRV 14274
Query: 249 RVEDLE-----AKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+ ++A +L+ + PGPPS+ + D +A+L W P G E+ G
Sbjct: 14275 SAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITG 14334
Query: 301 YMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKEL 358
Y+V+ W T T + DL Y+FR+ + N G+ A +
Sbjct: 14335 YVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-- 14392
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
I + ++A DF + L G S ++F ++ P P++ W K+
Sbjct: 14393 VEIVEREMAP--------DFELDAELRRTLVVRA---GLSIRIFVPIKGRPAPEVTWTKD 14441
Query: 419 KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ ++ + + L I + + +D+G + N G+ S
Sbjct: 14442 NINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 14485
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/411 (21%), Positives = 155/411 (37%), Gaps = 40/411 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ + S +SWEPP G + Y+++ W VSA + +T
Sbjct: 13015 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSAT-VPIT 13073
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+V L G ++ R+ A + G G P + +P + + P P + I +
Sbjct: 13074 SCSVEKLIEGHEYQFRICAENKYGVGDP-VFTEPAIAKNPYDPPGRCDPPVISN--ITKD 13130
Query: 189 GETVNLQIPFQGKPKP------------QATWTHNGHALDSQRVSMRTGDQDSILF---I 233
TV+ + P P WT +R TG Q+ + +
Sbjct: 13131 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 13190
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
+ ++ G+ +KA PGPP+ ++ D + +L W P
Sbjct: 13191 TAINKAGPGK-------PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYD 13243
Query: 294 GNTELLGYMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
G + ++GY+V+ + W + + T ++ L+ Y FRV++ N G S
Sbjct: 13244 GGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13303
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ V + H K DI P+G ++ D + G + +L+ V+ P P
Sbjct: 13304 SDVPDK--HYPK-DILIPPEGELDADLRKTLILRA---------GVTMRLYVPVKGRPPP 13351
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
KI W K + ++ S L + +D+G Y N G+
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 13402
Score = 81.6 bits (200), Expect = 1e-15
Identities = 99/427 (23%), Positives = 165/427 (38%), Gaps = 49/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP V D+VS+ V +SWEPP G + Y++E + W VS
Sbjct: 18032 KPGPPVGPV-------RFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS 18084
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A T + + L G ++ R+ A + G P LD I ++ P + P
Sbjct: 18085 ATVARTTIK-ITKLKTGTEYQFRIFAENRYGKSAP--LDSKAVI---VQYP-FKEPGPPG 18137
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM------RTGDQDSILFIRS 235
++ + + L + + T H ++ S+ +T QD+ ++
Sbjct: 18138 TPFVTSISKDQML-VQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF--KT 18194
Query: 236 AQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAALQWTPP 290
+ YE V E++ + V + V P PP + + N L+W P
Sbjct: 18195 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18254
Query: 291 QDTGNTELLGYMVQKADKKTGQWF-----TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
G +++ GY+V+K D G+W VLE T T+S L+ Y FRV + N
Sbjct: 18255 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLE----TEFTVSGLVEDQRYEFRVIARNA 18310
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
G + + + I D P ++ P + + H G + L +
Sbjct: 18311 AGNFSEPSDSS--GAITARDEIDAPNASLD------PKYKDVIVVHA---GETFVLEADI 18359
Query: 406 RASPKPKIIWMKNKMEIQGN-PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
R P P ++W K+ E++ + S TL ++ D G Y K NV G S
Sbjct: 18360 RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18419
Query: 465 VDCRLEV 471
+ ++V
Sbjct: 18420 IPITVKV 18426
Score = 81.6 bits (200), Expect = 1e-15
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 17/229 (7%)
Query: 251 EDLEAKAVIDILV-IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ LE +V+ I EKPG P + V + + W PP G ++ Y ++K +KK
Sbjct: 24436 DPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKK 24495
Query: 310 TGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAA 368
+W +V E T ++ +LI G Y FRV ENL G S + +++ + K+D+
Sbjct: 24496 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT--PKSDVPI 24553
Query: 369 KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNP-K 427
+AP F + L + + L C V PKP + W + EI + K
Sbjct: 24554 -----------QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24602
Query: 428 YRALS-EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
YR + G L I + D+ VY +A N G S LEV+ A
Sbjct: 24603 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPA 24651
Score = 80.1 bits (196), Expect = 4e-15
Identities = 103/486 (21%), Positives = 178/486 (36%), Gaps = 60/486 (12%)
Query: 4 KNTSEGPACSPEETASESAKVPTAEPPG--EVAVSESTREEQVPKPQAPAPQAPTASTAT 61
K T+ S + S S K + E G E+ VS S VP T
Sbjct: 19064 KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPI---------TIIVLD 19114
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP + +D+VS S+T+SW PPE G + Y++E ++ W VS
Sbjct: 19115 RPGPPGP--------IRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS 19166
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAV-----SSAGAGPPAMLDQPIHIRENIEAPKIRV 176
+ + VR L G ++ RV A SS + + P PK+
Sbjct: 19167 QAVARTSIKIVR-LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV-- 19223
Query: 177 PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSA 236
+ + V Q+P G+ L+ + S + + + I
Sbjct: 19224 ------VHATKSTMLVTWQVPVNDGGSRVI-----GYHLEYKERSSILWSKANKILIADT 19272
Query: 237 QRSDSG-----RYELTVRVEDLE-----AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
Q SG YE V E++ +K+ + + PP + ++ + +L+
Sbjct: 19273 QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLK 19332
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENL 345
W+ P G ++ GY+V++ + G+W T +++L Y FRVF+ N
Sbjct: 19333 WSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNA 19392
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
+ + ++ I D P+ ++ F + G ++ +
Sbjct: 19393 A--DSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI---------VVKAGEVLKINADI 19441
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
P P I W K+ +EI+ + +S L ++ D+G Y NV G SV
Sbjct: 19442 AGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSV 19501
Query: 466 DCRLEV 471
+V
Sbjct: 19502 AVNCKV 19507
Score = 79.7 bits (195), Expect = 5e-15
Identities = 57/211 (27%), Positives = 89/211 (42%), Gaps = 16/211 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + E+P PP I L+DV + +L W P+ G + +LGY+V+ K + +
Sbjct: 15663 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 15722
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T T TI+ LI G YSFRV ++N G+S ++ +
Sbjct: 15723 WAT-CATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV-------------- 15767
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
I +D P+F T G ++ P P + W K+ + ++ + A S
Sbjct: 15768 -IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 15826
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ L I+ D G Y K N GEA
Sbjct: 15827 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857
Score = 79.0 bits (193), Expect = 9e-15
Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 12/205 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P PP +++ D + L W PP++ G + + GY+V++ + + +W E T
Sbjct: 7216 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7275
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
++ L G Y++RV + N G S + T+E IQ D P+ F++ +
Sbjct: 7276 VTGLEEGKWYAYRVKALNRQGASKPSRPTEE---IQAVDTQEAPEIFLD---------VK 7323
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
LA T G +L +V P+PKI W K M ++ + + + T+ I
Sbjct: 7324 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 7383
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
D+G Y +A+NV G A+ + V
Sbjct: 7384 SDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 78.6 bits (192), Expect = 1e-14
Identities = 87/447 (19%), Positives = 169/447 (37%), Gaps = 72/447 (16%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
++P+ PS+ V PS P L + +++ ++ + W PE+ G + Y++E
Sbjct: 7694 SEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDV 7753
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
W V + T+ TV L G ++ RV+A ++ G ++ + ++ P
Sbjct: 7754 RRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP 7812
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
Y V + + + +P N QR + ++ +
Sbjct: 7813 G--------PPYALAVVDVTKRHVDLKWEPPK------NDGGRPIQRYVIEKKERLGTRW 7858
Query: 233 IRSAQRSDSG-RYELTVRVEDLEAKAVI---------------DILVIEKP----GPPSS 272
+++ + + + +T +E E + + +IL IE P PP
Sbjct: 7859 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLD 7918
Query: 273 IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDL-- 330
+ + D + A+ W PP+ G + ++GY V+ T +W V R I DL
Sbjct: 7919 LHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSR------PIKDLKF 7972
Query: 331 ------IIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ Y RV + N G+S + +++ + + +D P+
Sbjct: 7973 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 8017
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
D G + RA P P + W K+ E++ + + ++ LE+ K
Sbjct: 8018 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 8077
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
D+G+YT N LG A+ ++V
Sbjct: 8078 VRADAGIYTITLENKLGSATASINVKV 8104
Score = 77.0 bits (188), Expect = 3e-14
Identities = 92/421 (21%), Positives = 155/421 (36%), Gaps = 53/421 (12%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP + V++ +T+ W PP G + Y++E W VS
Sbjct: 20593 KPGPPGGPIE-------FKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS 20645
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + G++++ RV AV+ G G P D + + +P
Sbjct: 20646 EH-LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPE--- 20701
Query: 182 QTYIRQVGETVNLQIPF------------QGKPKPQATWTH--NGHALDS-QRVSMRTGD 226
T I + TV P + + K W D+ Q+V+ T +
Sbjct: 20702 VTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTEN 20761
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
D + + + G + E E D I+ PGPP+ IR+ D + L
Sbjct: 20762 SDYQYRVCAVNAAGQGPFS-----EPSEFYKAAD--PIDPPGPPAKIRIADSTKSSITLG 20814
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSEN 344
W+ P G + + GY+V+ + +W TV + T +S+L G +Y FRV + N
Sbjct: 20815 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVN 20874
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTST---PGYSTQL 401
G + + + +D EAP +A TS G Q+
Sbjct: 20875 CAGQGEPIEMNEPVQ---------------AKDILEAPEIDLDVALRTSVIAKAGEDVQV 20919
Query: 402 FCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P P + W K++ + + +Y + L I + + D+G Y N +G
Sbjct: 20920 LIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20979
Query: 462 E 462
E
Sbjct: 20980 E 20980
Score = 75.9 bits (185), Expect = 8e-14
Identities = 60/238 (25%), Positives = 98/238 (41%), Gaps = 24/238 (10%)
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
+ +I + R ++ G + V VE ++A + E P PP + L DV +A+L
Sbjct: 17809 EGAIYYFRVMAENEFG---VGVPVETVDA-----VKAAEPPSPPGKVTLTDVSQTSASLM 17860
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W P+ G + +LGY+V+ K T +W V E ++ L G Y FRV + N
Sbjct: 17861 WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQEYQFRVKAYNEK 17919
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
G K+D I +D + PS P ++ G ++ V
Sbjct: 17920 G---------------KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVI 17964
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P+P I W+K+ ++ + L I++ + D G YT A N G A+
Sbjct: 17965 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 18022
Score = 74.7 bits (182), Expect = 2e-13
Identities = 95/428 (22%), Positives = 168/428 (39%), Gaps = 54/428 (12%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PPS+ P P+ D++ + SV +SW+ PE G + Y +E + W V +
Sbjct: 21284 PPSK--PKGPI--RFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21339
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTY 184
T + V NL ++ RV A + G + QP+ + + R+P
Sbjct: 21340 ARTTFK-VPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPG------ 21386
Query: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR- 243
G+ V + G ++G + + + +++SIL+ + SGR
Sbjct: 21387 --PPGKPVIYNVTSDGMSLTWDAPVYDGGS-EVTGFHVEKKERNSILWQKVNTSPISGRE 21443
Query: 244 YELTVRVEDLE-------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
Y T VE L+ +K + + ++ PG P I DV
Sbjct: 21444 YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETIT 21500
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L+W PP G ++++GY ++K T++ L G+ Y FR+ + N
Sbjct: 21501 LKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARN 21560
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G T + ++ I D P +E P + L + G S ++
Sbjct: 21561 AVG--TISPPSQSSGIIMTRDENVPP--IVEF----GPEYFDGLIIKS---GESLRIKAL 21609
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V+ P P++ W K+ +EI+ G +L +R + GVYT +A N G A
Sbjct: 21610 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21669
Query: 465 VDCRLEVK 472
+ +++V+
Sbjct: 21670 AEIKVKVQ 21677
Score = 72.8 bits (177), Expect = 6e-13
Identities = 91/421 (21%), Positives = 155/421 (36%), Gaps = 39/421 (9%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ L ++ +++ ++SW P+ G + Y++E W +
Sbjct: 19510 KPGPPAGP-------LEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-IC 19561
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ +T V L G++++ RV+ V+ G G P + I + P P L
Sbjct: 19562 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP-LESVAIKALDPFTVPS--PPTSLE 19618
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDS 241
T + + T+ P + + +S R L ++S +
Sbjct: 19619 ITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREG 19678
Query: 242 GRYELTVRVED---LEAKAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
YE V E+ L + L+ + P PPS +++D + W P
Sbjct: 19679 CEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFD 19738
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
G + GY V+ W T ++ T TIS L G Y FRV S N G S +
Sbjct: 19739 GGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSD 19798
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCSVRASPK 410
++ P+ I ++ E P F ++ G S + R P
Sbjct: 19799 -------------SSDPQ--IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 19843
Query: 411 PKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
P ++W K +++ + T+E + DSG YT NVL AS+ ++
Sbjct: 19844 PNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRN--DSGKYTLTIQNVLSAASLTLVVK 19901
Query: 471 V 471
V
Sbjct: 19902 V 19902
Score = 72.4 bits (176), Expect = 8e-13
Identities = 49/217 (22%), Positives = 89/217 (41%), Gaps = 16/217 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ I V E P PP I + DV + +L WT P+ G ++++ Y+V+ K + +
Sbjct: 16745 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEK 16804
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W + R I++L G Y FRV + N G S ++ +
Sbjct: 16805 W-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI-------------- 16849
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+ +D P + ++ G ++ + PKP I W K+ + ++ +
Sbjct: 16850 -VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTD 16908
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRL 469
+ TL I++ D G Y NV+G+ + +
Sbjct: 16909 SLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 16945
Score = 71.2 bits (173), Expect = 2e-12
Identities = 68/289 (23%), Positives = 112/289 (38%), Gaps = 12/289 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + DV++ S ++W PP G + YV+E + W +S+ + T
Sbjct: 7410 DKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSS-TVKDT 7468
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
L +++ RV+A + G G P PI + + P P L + I +
Sbjct: 7469 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA-SPITAKYQFDPP--GPPTRLEPSDITKD 7525
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
T+ P P + D+ + R ++ +Y V
Sbjct: 7526 AVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRV 7585
Query: 249 RVEDL-----EAKAVIDILV---IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+L +K+ IL+ I+ P PP + DV + L WT P+ G ++
Sbjct: 7586 LAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIES 7645
Query: 301 YMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+++ T +W V E T + L+ G YSFRV + N G S
Sbjct: 7646 YVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 7694
Score = 69.3 bits (168), Expect = 7e-12
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 20/215 (9%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + V E P PP + L+DV A ++W P+ G +++ GY+V+ K + +
Sbjct: 18910 LPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEK 18969
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T + TIS L G Y FRV + N G ++D
Sbjct: 18970 WSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKG---------------RSDPRQLGVP 19013
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV--RASPKPKIIWMKNKMEIQGNPKYRA 430
I RD PS P HT QL V + P+ + W K+ ++ +
Sbjct: 19014 VIARDIEIKPSVELPF--HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNV 19071
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
S + V +L I++ S D G Y N G +V
Sbjct: 19072 SSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 19106
Score = 68.2 bits (165), Expect = 2e-11
Identities = 97/427 (22%), Positives = 157/427 (36%), Gaps = 57/427 (13%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSARPMM 126
D P P+ +D+ +SV WEPP G + Y LE + SEW+ V++ +
Sbjct: 8428 DTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTS-TLR 8486
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR 186
+ +V L G ++L RV A + G GPP + +P+ ++ P + +
Sbjct: 8487 HCKYSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAP-----DKPIVE 8540
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG---- 242
V T N + +PK + G+ L+ + V+ + + + + + + G
Sbjct: 8541 DV--TSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 8597
Query: 243 -RYELTVRVEDL----------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
Y V E+ + K D I PGPP R+ D L+W PP
Sbjct: 8598 LTYVFRVCAENAAGPGKFSPPSDPKTAHD--PISPPGPPIP-RVTDTSSTTIELEWEPPA 8654
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGL-- 348
G E++GY V K T +W E+ T+ ++ G Y RV + N G
Sbjct: 8655 FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGP 8714
Query: 349 --STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
T E ++ KG I+ G + ++ V
Sbjct: 8715 PGETQPVTVAEPQEPPAVELDVSVKGGIQ-----------------IMAGKTLRIPAVVT 8757
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQ--GVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P +W K + E+ K R + + L I+ D G Y A N G
Sbjct: 8758 GRPVPTKVWTKEEGELD---KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 8814
Query: 465 VDCRLEV 471
R+EV
Sbjct: 8815 AAARVEV 8821
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/235 (22%), Positives = 94/235 (40%), Gaps = 30/235 (12%)
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
F R ++ G E T E ++A E P PP S+ ++D+ +L W P+
Sbjct: 14566 FFRVMAENEYGIGEPTETTEPVKAS--------EAPSPPDSLNIMDITKSTVSLAWPKPK 14617
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS-- 349
G +++ GY+++ K + QW T + C + +L G Y+F+V + N G S
Sbjct: 14618 HDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 14676
Query: 350 --TSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+ + KE + + D+ + + + G + ++ V
Sbjct: 14677 RESRPVIVKEQTMLPELDLRGIYQKLV-----------------IAKAGDNIKVEIPVLG 14719
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
PKP + W K ++ + + L I + DSG Y A N++GE
Sbjct: 14720 RPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 14774
Score = 66.6 bits (161), Expect = 5e-11
Identities = 85/431 (19%), Positives = 158/431 (36%), Gaps = 63/431 (14%)
Query: 69 DVPSAPLL-LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D P P + D+ + + ++SW P G + Y++E C +WV A +
Sbjct: 12618 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTK 12676
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T V L G +++ RV A + G + +P+ + + VP + + +
Sbjct: 12677 TSCRVGKLIPGQEYIFRVRAENRFG------ISEPLTSPKMVAQFPFGVPSEPKNARVTK 12730
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRS-DSGRYEL 246
V N F +P + G + + + +++S+L++++ S Y
Sbjct: 12731 V----NKDCIFVAWDRPDSD---GGSPIIGYLIERK--ERNSLLWVKANDTLVRSTEYPC 12781
Query: 247 TVRVEDLEAKAVIDILVIEKPG------------------PPSSIRLLDVWGCNAALQWT 288
VE LE I + K G PP ++DV +L W
Sbjct: 12782 AGLVEGLEYS--FRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWA 12839
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
P+ G ++++GY V+ +W T + T + L Y FR +
Sbjct: 12840 RPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTA 12899
Query: 346 CGLSTSATVTKELAHIQ-----KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
+S + + + + + D++ K + T G +
Sbjct: 12900 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL-----------------TVKAGTNVC 12942
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L +V P P + W K+ ++ + ++ +CTLE+ + DSG YT A N
Sbjct: 12943 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 13002
Query: 461 GEASVDCRLEV 471
G S +L+V
Sbjct: 13003 GSKSATIKLKV 13013
Score = 66.2 bits (160), Expect = 6e-11
Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 31/222 (13%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-----KADKKTGQWFTVLE 318
I P PP +++ + L W PP++ G + + Y+V+ K W +
Sbjct: 9637 IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK 9696
Query: 319 R-YHPTTCTISDLIIGNSYSFRVFSENLCGLST-SATVTKELAHIQKADIAAKPKGFIER 376
R T+ DL+ G Y FRV + N G+S SATV Q+ D+ P +
Sbjct: 9697 RDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGP--CDCQRPDM---PPSIDLK 9751
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK-------NKMEIQGNPKYR 429
+F E G + + ++ P P + W K NK + +
Sbjct: 9752 EFMEVEE------------GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN 9799
Query: 430 ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L CTL I + D+G+YT A+N LG AS + RL V
Sbjct: 9800 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9841
Score = 66.2 bits (160), Expect = 6e-11
Identities = 91/429 (21%), Positives = 169/429 (39%), Gaps = 73/429 (17%)
Query: 77 LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLA 136
+ + VS+ S +SW P+ G + Y++E G + W V++ + TQ V +L
Sbjct: 22376 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLT 22434
Query: 137 LGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQI 196
++ RVS+ + G P L+ I E+ P P ++ ++ +
Sbjct: 22435 KYMEYSFRVSSENRFGVSKP--LESAPIIAEHPFVPP-SAPTRPEVYHVSANAMSIRWEE 22491
Query: 197 PFQ-GKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSD-SGRYELTVRVEDLE 254
P+ G K W ++++IL+++ + Y++T VE LE
Sbjct: 22492 PYHDGGSKIIGYWVEKK-------------ERNTILWVKENKVPCLECNYKVTGLVEGLE 22538
Query: 255 -------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
++ ++ ++ PG P + DV +L W+ P G
Sbjct: 22539 YQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VTDVTRSTVSLIWSAPAYDGG 22595
Query: 296 TELLGYMVQK---ADKKTGQW----FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++++GY++++ ++ G+W +T++ T +S+ G++Y FRV ++N G+
Sbjct: 22596 SKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE---GDTYEFRVLAKNAAGV 22652
Query: 349 ------STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
ST ++ KA++ A+ G + T G L
Sbjct: 22653 ISKGSESTGPVTCRDEYAPPKAELDARLHGDLV----------------TIRAGSDLVLD 22696
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
+V P+PKIIW K E+ K T I+ DSG YT N G
Sbjct: 22697 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 22756
Query: 463 ASVDCRLEV 471
+V ++V
Sbjct: 22757 KAVSVMVKV 22765
Score = 65.1 bits (157), Expect = 1e-10
Identities = 92/432 (21%), Positives = 162/432 (37%), Gaps = 47/432 (10%)
Query: 56 TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
T +P PP PL +T V++ ++W PP + G + Y++E
Sbjct: 18423 TVKVLDRPGPPE-----GPLKVT--GVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL 18475
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP--- 172
W VS + + V L G++++ RV AV+ G G P + P+ + P
Sbjct: 18476 SWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEP-LESGPVTACNPYKPPGPP 18533
Query: 173 -----KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRT 224
+ T+ R V G T + + K WT N L R+ +
Sbjct: 18534 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 18593
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
+ R A + +G E + E D L PGPPS+ ++ D + +
Sbjct: 18594 LTEGHSYEFRVAAENAAGVGEPS---EPSVFYRACDALY--PPGPPSNPKVTDTSRSSVS 18648
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-----TISDLIIGNSYSFR 339
L W+ P G + GY+V+ + +W T PT T++ L Y+FR
Sbjct: 18649 LAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP---PTGLQGKQFTVTKLKENTEYNFR 18705
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
+ + N G+ AT+ + ++ + P+ ++ D + +
Sbjct: 18706 ICAINSEGVGEPATLPGSVVAQERIE---PPEIELDADLRKVVVLRASA---------TL 18753
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
+LF +++ P+P++ W K + + + S L I + FDSG Y N
Sbjct: 18754 RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTLENN 18811
Query: 460 LGEASVDCRLEV 471
G + + V
Sbjct: 18812 SGSKTAFVNVRV 18823
Score = 63.2 bits (152), Expect = 5e-10
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Query: 59 TATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASE 116
T +KP A D P P + VS +TV W PPE G + GY LE + ++
Sbjct: 12010 TESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 12069
Query: 117 WVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WVPV+ + + V+NL ++ RV A + G G P++ +P+ ++ IE P
Sbjct: 12070 WVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP 12125
Score = 63.2 bits (152), Expect = 5e-10
Identities = 53/201 (26%), Positives = 82/201 (40%), Gaps = 5/201 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P L + +S SVT+ WE PE G + GY +E + G S W + +
Sbjct: 24057 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 24116
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR-ENIEAPKIRVPRHLRQTYIRQ 187
Q T+ L ++ RV A + G P I + + EAP IR + +
Sbjct: 24117 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTK 24173
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
+GE L G+P P W G L S++ M + + L + + ++ D G Y
Sbjct: 24174 LGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 24233
Query: 247 TVRVEDLEAKAVIDILVIEKP 267
E E + +L+ P
Sbjct: 24234 IATNEVGEVETSSKLLLQATP 24254
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 25/211 (11%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+LV E P P+ + ++DV L W P G + L GY+++ T +W V+
Sbjct: 23257 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT-L 23315
Query: 321 HPTTC--TISDLIIGNSYSFRVFSENLCGLS-----TSATVTKELAHIQKADIAAKPKGF 373
PT T++ L G Y FR+ ++N G+S +A ++L + D++ P+
Sbjct: 23316 KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKT 23375
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I P+ G +L + P P W +++ + + +
Sbjct: 23376 IH-----VPA------------GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 23418
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V L IR+ + D+G YT + NV G S
Sbjct: 23419 TKVAKLTIRETTIRDTGEYTLELKNVTGTTS 23449
Score = 61.6 bits (148), Expect = 1e-09
Identities = 33/103 (32%), Positives = 55/103 (53%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + DVS +T++W PPE G + GY++E A WV V+ P+ +T+
Sbjct: 23559 IPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 23618
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
L G ++ RV+A+++ G+G P+ +PI + I P
Sbjct: 23619 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPP 23661
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/104 (32%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV-SARPMMVT 128
VP AP + +++ +S+T++W PE G +Q Y+LE + ++ WV V S RP+ T
Sbjct: 21779 VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISET 21838
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ V L G+++ V A ++AG GP + + + I RE + P
Sbjct: 21839 RFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 21882
Score = 58.5 bits (140), Expect = 1e-08
Identities = 62/272 (22%), Positives = 104/272 (38%), Gaps = 34/272 (12%)
Query: 208 WTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKP 267
WT + + Q +++ Q F R A + G VE EA + + + + P
Sbjct: 10291 WTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPF---VETSEALVIREPITV--P 10345
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT--- 324
P + + +V L W PP+ G +E++ Y+++ T E++H T
Sbjct: 10346 ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT-------EKFHKVTNDN 10398
Query: 325 -----CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFS 379
T+ L G++Y +RV + N+ G + TK I D A P + DF
Sbjct: 10399 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAPPT--LHLDFR 10453
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
+ T G + L PKPK+ W K++ ++ + + + L
Sbjct: 10454 DKL---------TIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLAL 10504
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
E K DSG Y N G C++ V
Sbjct: 10505 EKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10536
Score = 58.5 bits (140), Expect = 1e-08
Identities = 64/267 (23%), Positives = 100/267 (37%), Gaps = 32/267 (11%)
Query: 207 TWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
TW+ H S + + + F R ++ G E E ++A V
Sbjct: 21039 TWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV-------- 21090
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P P + + D + L WT P G + + Y+V++ K W TC
Sbjct: 21091 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWS---HAGISKTCE 21147
Query: 327 I--SDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
I S L + FRVF++N GLS T+ I ++ P E D S+ P
Sbjct: 21148 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----GPITVKELIITP----EVDLSDIPG- 21198
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
A T G++ L + PKP I W+K+ + ++ + R + TL I+
Sbjct: 21199 ----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21254
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
G YT N + CR+ V
Sbjct: 21255 KKEHGGKYTVILDNAV------CRIAV 21275
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPM---- 125
VP AP T+ V+ +S+TV+WE PE G + GY LE+ + W V+ P+
Sbjct: 9944 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 10003
Query: 126 MVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
+ V L G + RV A+++AG GP ++ P R+ I P P+
Sbjct: 10004 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPK 10056
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/104 (29%), Positives = 52/104 (50%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP AP + DV SV+++W P++ G + GY LE + W + P+ +
Sbjct: 13802 DVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMR 13861
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ RV A++ AG G P++ +P+ + I+ P
Sbjct: 13862 DFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13905
Score = 57.8 bits (138), Expect = 2e-08
Identities = 48/208 (23%), Positives = 79/208 (37%), Gaps = 27/208 (12%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
I+ E+P PP + ++D +A L W P G + + GY+++ K + W +E
Sbjct: 22168 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW---VEAG 22224
Query: 321 H--PTTCTISDLIIGNSYSFRVFSENLCGLST-----SATVTKELAHIQKADIAAKPKGF 373
H T T+ L+ Y FRV ++N G S S+ + KE AD+
Sbjct: 22225 HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL 22284
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I T G + + P PK+ W +M ++ + +
Sbjct: 22285 I-----------------TCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTT 22327
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ TL ++ DSG Y N G
Sbjct: 22328 KDRTTLTVKDSMRGDSGRYFLTLENTAG 22355
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/98 (31%), Positives = 44/98 (44%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
+ ++ S+AP+F G + C + P P+I W KN + I +
Sbjct: 26754 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 26813
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ V +LEIR S DSG YT KA N G+ S L V
Sbjct: 26814 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/93 (30%), Positives = 44/93 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ L + T G S L C + P P + W + +I+ + ++ + G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
R+ DSG +TC A+N G S C L V+ S
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 57.4 bits (137), Expect = 3e-08
Identities = 55/218 (25%), Positives = 89/218 (40%), Gaps = 27/218 (12%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT-- 324
PGPPS + D + +L W PP G + + GY+V+ ++ T W V E T
Sbjct: 9333 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9392
Query: 325 -CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
C + +L Y FRV + N G S + T E I DI +P+ FI+ +
Sbjct: 9393 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGE---IPATDIQEEPEVFIDIGAQDCL- 9448
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIW---------MKNKM-EIQGNPKYRALSE 433
G ++ ++ P PK W MK+ + +I + +
Sbjct: 9449 --------VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAEN 9500
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
V + K S +G Y+ A N G+ + +CR++V
Sbjct: 9501 SSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 9536
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 1/153 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P AP T+ V+ S V+W+PP G ++ Y LE + ++W+ V+ + T
Sbjct: 24453 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 24512
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
+V+NL G ++ RV + G + + +PI + ++ LR +R
Sbjct: 24513 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVR-YQS 24571
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMR 223
L G PKP W G + + + R
Sbjct: 24572 NATLVCKVTGHPKPIVKWYRQGKEIIADGLKYR 24604
Score = 56.6 bits (135), Expect = 5e-08
Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
+T +TVT++ +PK S P L D T + +
Sbjct: 26459 TTESTVTRK----------TEPKA--PEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGE 26506
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P+P IW K+ I KY+ ++G LEI K DSG+YTC N G S C+
Sbjct: 26507 PRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCK 26566
Query: 469 LEVKA 473
L +KA
Sbjct: 26567 LTIKA 26571
Score = 55.8 bits (133), Expect = 8e-08
Identities = 57/237 (24%), Positives = 85/237 (35%), Gaps = 46/237 (19%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-T 323
+ P PP + + + + W PP G ++++GY+++K K +W E P
Sbjct: 8206 QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL 8265
Query: 324 TCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
T T L G Y FRV +EN G+S + T + D PK +
Sbjct: 8266 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPID---APKVILRTSLE---- 8318
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN--------------------KMEIQ 423
G L S+ SP P I W+K+ K E+Q
Sbjct: 8319 ---------VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQ 8369
Query: 424 GN-----PKYRAL----SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
P + L S++G L +R D G+Y K N G A C + V
Sbjct: 8370 EEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426
Score = 55.1 bits (131), Expect = 1e-07
Identities = 51/211 (24%), Positives = 84/211 (39%), Gaps = 26/211 (12%)
Query: 258 VIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
++ I I++PG P ++ + D L+W P G + L Y V++ K + W V
Sbjct: 11720 ILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH 11779
Query: 318 ERYHPTTCTISDLIIGNS-YSFRVFSENLCG----LSTSATVTKELAHIQKADIAAKPKG 372
+ T + D + N Y FRV ++N G + T V KE +QK + K G
Sbjct: 11780 KGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKE--DLQKPVLDLKLSG 11837
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK--MEIQGNPKYRA 430
+ T G + +L VR P P++ W K+K ++ +P+ +
Sbjct: 11838 VL-----------------TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11880
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ + K D G Y A N G
Sbjct: 11881 DTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11911
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PSAP+ LT+ +V SVT+SWEPP G + Y++E RE + T
Sbjct: 18825 DSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEK-RETTRKAYATITNNCTKT 18883
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ NL G + RV A + G G PA +P+ + E
Sbjct: 18884 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE 18922
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/201 (20%), Positives = 82/201 (40%), Gaps = 13/201 (6%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+ + EKP PP + + + + +L W P+ G + ++ Y+V+ +K W
Sbjct: 19997 VKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA- 20055
Query: 321 HPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE 380
T +S L + Y FRVF+EN GLS + + ++ + E D
Sbjct: 20056 KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPP-------EIDMKN 20108
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
PS T + G + ++ + P PK+ ++ + ++ ++ T+
Sbjct: 20109 FPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTIN 20163
Query: 441 IRKPSPFDSGVYTCKAINVLG 461
+++ D+G Y A N G
Sbjct: 20164 LKESVTADAGRYEITAANSSG 20184
Score = 53.1 bits (126), Expect = 5e-07
Identities = 46/197 (23%), Positives = 82/197 (41%), Gaps = 16/197 (8%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT 324
+ PGP +++ V + ++ W P G + ++GY+V ++ +W V++
Sbjct: 13510 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQ 13567
Query: 325 CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ DL G Y+FRV +EN G T + +T + + D+ A + D P
Sbjct: 13568 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV----VARDDVVAP-----DLDLKGLPDL 13618
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
LA S + +L ++ P P + W K + + + + S TL +
Sbjct: 13619 CY-LAKENS----NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 13673
Query: 445 SPFDSGVYTCKAINVLG 461
D+G YT NV G
Sbjct: 13674 QKSDAGKYTITLKNVAG 13690
Score = 53.1 bits (126), Expect = 5e-07
Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
Query: 55 PTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P S A K P VPS P L + V+ S+T+ W PE G + GY++E + +
Sbjct: 19596 PLESVAIKALDPFT-VPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNS 19654
Query: 115 SEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WV V+ +P+ + L G ++ RV A ++AG P+ I + + P
Sbjct: 19655 LRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19712
Score = 52.8 bits (125), Expect = 7e-07
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 19/154 (12%)
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T + + + + R G Y ++ E +E ++ I I PGPP ++++ DV
Sbjct: 23525 TEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGM 23576
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV------LERYHPTTCTISDLIIGNSYS 337
L W PP+D G +++ GY+V++ + + +W V + RY T L G Y
Sbjct: 23577 TLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRST-----GLTEGLEYE 23631
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPK 371
RV + N G + +K + + KP+
Sbjct: 23632 HRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQ 23665
Score = 52.4 bits (124), Expect = 9e-07
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DV+ +S VSW PPE G + Y++E W V+ + T
Sbjct: 12325 DTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPE-VKKT 12383
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V NL G+++ RV+AV+ G G P + +P+ + + P PR L T + +
Sbjct: 12384 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPD--PPRKLEVTEMTKN 12441
Query: 189 GETV 192
T+
Sbjct: 12442 SATL 12445
Score = 52.4 bits (124), Expect = 9e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE+ V+ PGPP S+ + ++ + + W P G +E++GY+V+K D+
Sbjct: 17431 EPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSG 17490
Query: 311 GQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+W R ++ L + Y FRV +EN G+ + T
Sbjct: 17491 IRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17536
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/91 (32%), Positives = 43/91 (47%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP T + H G +T+ +V++ P ++ W N +E+Q + K + GV TLE
Sbjct: 26001 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 26060
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
I DSG Y N GEAS L+V
Sbjct: 26061 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/287 (21%), Positives = 105/287 (36%), Gaps = 19/287 (6%)
Query: 200 GKPKPQATWTHNGHALDS---QRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAK 256
G PKP W +G L + +VS + L I D+G Y + VR + E
Sbjct: 1061 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1120
Query: 257 AVIDIL------VIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK- 309
A +L ++ K S +L A +Q +T G++ + +K+
Sbjct: 1121 ASASLLEEADYELLMK----SQQEMLYQTQVTAFVQEPKVGETAP----GFVYSEYEKEY 1172
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK 369
+ + ++ T + + + F E L + L + + D K
Sbjct: 1173 EKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEK 1232
Query: 370 PKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR 429
I + F + ++ G C + P PKI W K+ I+ +Y+
Sbjct: 1233 MAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQ 1292
Query: 430 A-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ G +L I P D G+YT A N+ G A +L V+ +A
Sbjct: 1293 MDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAA 1339
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/225 (24%), Positives = 85/225 (37%), Gaps = 30/225 (13%)
Query: 261 ILVIEKPGPPSSIRLL---DVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
IL ++ GPP+S L + L W P+ G + + GY+++K + V
Sbjct: 8914 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8973
Query: 318 ERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIER 376
+R PTT + +L Y FRV + N G S + P + +
Sbjct: 8974 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNVVIQ 9017
Query: 377 DFSEAPSFTQPLADHTST----PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D P+ L+ T G + V P PKI W KN+ I+ ++
Sbjct: 9018 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 9077
Query: 433 EQGV------CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ V L I K D G YT A N LG + +EV
Sbjct: 9078 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9122
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T+ DV+ S +SW+ PE G ++ Y +E WV V+ ++
Sbjct: 19904 DTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLS 19963
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+ V NL G + RVS + G G PA + + I E P+
Sbjct: 19964 YK-VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 20007
Score = 50.8 bits (120), Expect = 3e-06
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T DV+ S T+ W+ P G + YV+E W +S + T
Sbjct: 22075 DTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK---CT 22131
Query: 129 QQ--TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+Q V +LA G + RVSAV+ G G P + +PI E P+
Sbjct: 22132 RQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPR 22178
Score = 50.4 bits (119), Expect = 3e-06
Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE++ V+ + P PP + + + + + W P G +E++ Y+V++ DK
Sbjct: 15267 EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAG 15326
Query: 311 GQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
+W ++ +S L G+ Y FR+ +EN G+S
Sbjct: 15327 QRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 15366
Score = 48.5 bits (114), Expect = 1e-05
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 12/196 (6%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P+ L + +++ SV+++WEPP G ++ Y++E RE +
Sbjct: 16660 DTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK-REATRKSYAAVVTNCHKN 16718
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP-KIRVPRHLRQ----- 182
+ L G + RV+A + G G PA PI + E + P KI V R
Sbjct: 16719 SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLS 16778
Query: 183 -TYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF----IRSAQ 237
T G + +Q + + K W+ Q V + LF +
Sbjct: 16779 WTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKG 16838
Query: 238 RSDSGRYELTVRVEDL 253
RSD + + +DL
Sbjct: 16839 RSDPRSLAVPIVAKDL 16854
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
D++ SS ++WEPPE G + YVLE G ++PV + ++ TV++L +
Sbjct: 8118 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGE 8176
Query: 141 FLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ RV AV+ G G L P+ ++ + P
Sbjct: 8177 YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8208
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/199 (21%), Positives = 75/199 (37%), Gaps = 17/199 (8%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-KADKKTGQWFTVLERYHP 322
+ +P PP + + ++ +A L W PP G ++ GY+ + +++ +T
Sbjct: 12424 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 12483
Query: 323 TTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAP 382
+ ++ L G Y FRV + N G+S + +E + +A P P
Sbjct: 12484 LSLVVTGLKEGKKYKFRVAARNAVGVS----LPREAEGVYEAKEQLLP-----------P 12528
Query: 383 SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
P T G ++ V P P W K + E+ + L I+
Sbjct: 12529 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12587
Query: 443 KPSPFDSGVYTCKAINVLG 461
+ DSG Y+ A N G
Sbjct: 12588 DVTRKDSGYYSLTAENSSG 12606
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC--REGASEWVPVSARPMM 126
D P+ P+++ + + +S +SW+PP G + YV+E C +EGA EW VS+ +
Sbjct: 24352 DKPTGPIVI--EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGA-EWQLVSS-AIS 24407
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
VT + NL + RVSA ++ G P + + I+ E P
Sbjct: 24408 VTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP 24453
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + DVS SV ++W P G + Y++E C A W+ V T
Sbjct: 24748 DVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARET 24805
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
+ TV NL + RV A + G P+ +P +E+
Sbjct: 24806 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKED 24845
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 83 SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP-----MMVTQQTVRNLAL 137
+ S+ VSW PP G + GY LE EG+ W VS P + + V L
Sbjct: 9239 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9298
Query: 138 GDKFLLRVSAVSSAGAGPPAMLDQP 162
G K+ R A+++AG GPP+ P
Sbjct: 9299 GVKYQFRAMAINAAGIGPPSEPSDP 9323
Score = 47.0 bits (110), Expect = 4e-05
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 14/144 (9%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T P PPS + +V+ S+TV W P G + GY LE+ + W
Sbjct: 20296 TTPGPPSTP--------WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKA 20347
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + T V ++ G + RV A ++AG G P+ +P+ + E PR++
Sbjct: 20348 NKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP-----PRNV 20402
Query: 181 RQTYIRQVGETVNLQIP-FQGKPK 203
R T I + +++ Q P F G K
Sbjct: 20403 RITDISKNSVSLSWQQPAFDGGSK 20426
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T P P E + P +L DV+ SSV++SW P+ G + GY +E +WV
Sbjct: 23949 TPKTPLNPPEPPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWV 24005
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ + T TV L ++ R+ A + G + +P+ ++ + P
Sbjct: 24006 RHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKP 24059
Score = 46.6 bits (109), Expect = 5e-05
Identities = 39/129 (30%), Positives = 52/129 (40%), Gaps = 10/129 (7%)
Query: 355 TKELAHIQKADIAA---------KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
TKEL +K +A KP EAP + + T G V
Sbjct: 1996 TKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV 2055
Query: 406 RASPKPKIIWMKNKMEIQGNPK-YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P+ W KN ++I+ + + Y E VC L IR + DS KAIN+ GE S
Sbjct: 2056 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2115
Query: 465 VDCRLEVKA 473
L V+A
Sbjct: 2116 SHAFLLVQA 2124
Score = 46.6 bits (109), Expect = 5e-05
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ---GNPKYRALSEQGVCT 438
P FT PL + T+ G + + ++ P+P + W K+ +I+ + KY S++G+
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L I + D YT A N GE S +L V
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/76 (31%), Positives = 36/76 (47%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G+ + C ++++P + W K EI + K S + + +LEI + D G YTCK
Sbjct: 4476 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 4535
Query: 456 AINVLGEASVDCRLEV 471
A N G S L V
Sbjct: 4536 ASNEYGSVSCTATLTV 4551
Score = 46.2 bits (108), Expect = 6e-05
Identities = 42/153 (27%), Positives = 61/153 (39%), Gaps = 3/153 (1%)
Query: 20 ESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTL 79
E A++ TAE + + E R K A TA DVP P L +
Sbjct: 9491 EDAQLETAENSSVIIIPECKRSH-TGKYSITAKNKAGQKTANCRVKVM-DVPGPPKDLKV 9548
Query: 80 DDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGD 139
D++ S +SW+ P+ G ++GYV+E W V+ T V +L
Sbjct: 9549 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNP-DCGSTTFVVPDLLSEQ 9607
Query: 140 KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
++ RV A + G GPP Q R+ I P
Sbjct: 9608 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 9640
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/88 (27%), Positives = 43/88 (48%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + +++ S+TV W P+ G + GY++E W+ + R + +
Sbjct: 17446 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 17505
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPA 157
V L ++ RVSA ++AG G P+
Sbjct: 17506 LRVTGLTEDHEYEFRVSAENAAGVGEPS 17533
Score = 46.2 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
PSAP + VS++++++ WE P G + GY +E WV + P +
Sbjct: 22469 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22528
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ R A+++AG + +PI + ++AP
Sbjct: 22529 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 22570
Score = 45.8 bits (107), Expect = 8e-05
Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 241 SGRYELTVRVED---LEAKAVIDILVIEKP----GPPSSIRLLDVWGCNAALQWTPPQDT 293
+G+YE VR + + + D +VI+ P GPP ++L + + WTPP D
Sbjct: 9194 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 9253
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTT--------CTISDLIIGNSYSFRVFSENL 345
G + + GY ++K ++ + W V P T + L+ G Y FR + N
Sbjct: 9254 GGSPITGYWLEKREEGSPYWSRVSRA--PITKVGLKGVEFNVPRLLEGVKYQFRAMAINA 9311
Query: 346 CGL 348
G+
Sbjct: 9312 AGI 9314
Score = 45.8 bits (107), Expect = 8e-05
Identities = 60/300 (20%), Positives = 105/300 (35%), Gaps = 40/300 (13%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ V G+P P+ W N + S VS+ L IR+A SDSG+Y +
Sbjct: 26776 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 26835
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG----YMV 303
+ + A ++V+ PS +L + +G+T L G V
Sbjct: 26836 AKNFRGQCSATASLMVLPLVEEPSREVVL--------------RTSGDTSLQGSFSSQSV 26881
Query: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSF--------RVFSENLCGLSTSATVT 355
Q + K F+ ++ T ++ S + S + G+S +
Sbjct: 26882 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 26941
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ + KA I P P +D + G + C+ P P++ W
Sbjct: 26942 SSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTW 26990
Query: 416 M--KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
K+ Q ++ + + TL I D G+YT N G S + +++
Sbjct: 26991 SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27050
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P P + K D P P++ +DV+S+S+ V W P+ G + GY LE
Sbjct: 8513 PGPPCVSKPLVAKDPFGPPDAPDKPIV---EDVTSNSMLVKWNEPKDNGS-PILGYWLEK 8568
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
++ W V+ + + V L G ++ RV A ++AG G + P + I
Sbjct: 8569 REVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPI 8628
Query: 170 EAPKIRVPR 178
P +PR
Sbjct: 8629 SPPGPPIPR 8637
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/93 (30%), Positives = 41/93 (44%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E P Q L T G + + P+PKI W K + + K + L + TL
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + P D+ VYTC+A N G A+ L V+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+PL D T G + L C V + K+ W KN EI + KY +++ V L I
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5973
Query: 444 PSPFDSGVYTCKA 456
+P D YTC A
Sbjct: 5974 CTPEDIKTYTCDA 5986
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGVCTL 439
P F + L + G ++ +P P I+W+KN I + PK R +G L
Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1569
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+I DS YT AIN G + C++ V+ A
Sbjct: 1570 KIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFA 1606
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/284 (20%), Positives = 102/284 (35%), Gaps = 42/284 (14%)
Query: 200 GKPKPQATWTHNGHALDSQRVSMRTGDQDS-ILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
G+P+P A WT +G A+ + D+ L I SDSG Y TV+
Sbjct: 26505 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--------- 26555
Query: 259 IDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
G SS L + + +TE QK + T Q V++
Sbjct: 26556 ------NSAGSVSSSCKLTI------------KAIKDTEAQKVSTQKTSEITPQKKAVVQ 26597
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
S+ I + S+ L A+ ++K+ + K + +
Sbjct: 26598 EEISQKALRSEEIKMSEAK----SQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 26653
Query: 379 SEAPSFTQPLADHTSTPGYSTQ--------LFCSVRASPKPKIIWMKNKMEIQGNPKYRA 430
++ ++ + H +STQ L + + W+ N +E+ + +YR
Sbjct: 26654 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 26713
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
TL I++ S D G+ TC I+ E V C+ ++ S
Sbjct: 26714 GVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDLTLS 26755
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 379 SEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGV 436
++AP+FTQPL G + + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
L I + +SG Y+ KA N G+A+ L VKA A
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102
Score = 43.5 bits (101), Expect = 4e-04
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 9/129 (6%)
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
S+S + T+E+A ++ I G I+ D P PL D S G L S+ +
Sbjct: 4341 SSSESGTEEVATVK---IQEAEGGLIKED---GPMIHTPLVDTVSEEGDIVHLTTSITNA 4394
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFD-SGVYTCKAINVLGEASVDC 467
+ + W + + K++ L +Q TL I K + D G Y C+A+N G+ +
Sbjct: 4395 KE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4452
Query: 468 RLEVKASAA 476
+L V AA
Sbjct: 4453 KLTVVKRAA 4461
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+F Q L T G +L V P P + + ++ EIQ + ++ E + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ P DSG Y+ A N +G A+ L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 2/105 (1%)
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI--QGNPKYRA 430
F + + PSF QPL+ G + + V PKP+I W N+ I + +
Sbjct: 3410 FKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHF 3469
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
G+ + I +G Y+CKA N GEA+ L V A
Sbjct: 3470 EESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKA 3514
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRAL-SEQGVCTLE 440
P F + L G +V P P + W K ++ + Y + + G T
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ P DSG+Y CKA N+LGE++ L V
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 54 APTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
AP S A P ++ P P + +S + V W P G + GY LE +
Sbjct: 18117 APLDSKAVIVQYPFKE-PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ WV ++ P+ T+ L G ++ +VSA + G G P+ + + R+ + P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18234
Score = 41.2 bits (95), Expect = 0.002
Identities = 67/326 (20%), Positives = 116/326 (35%), Gaps = 44/326 (13%)
Query: 156 PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL 215
P I + ++EAPKI ++ + Q G + ++ GKP P+ W NG +
Sbjct: 2016 PTFKPDKIELSPSMEAPKIF--ERIQSQTVGQ-GSDAHFRVRVVGKPDPECEWYKNGVKI 2072
Query: 216 DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRL 275
+ +D++ EL +R E A I + I G SS
Sbjct: 2073 ERSDRIYWYWPEDNVC-------------ELVIRDVTAEDSASIMVKAINIAGETSSHAF 2119
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
L V T EL + ++ D E + + +
Sbjct: 2120 LLVQAKQLI--------TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEG 2171
Query: 336 YSFRVFSE------NLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLA 389
+R+ S+ ++ + TS ++ ++ K +E E F + L
Sbjct: 2172 DKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVE---FVKELQ 2228
Query: 390 DHTSTPGYSTQLFCSVRASPKPKII---WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
D YS +L C V P+ I W N +E++ N KY S +G L ++ +
Sbjct: 2229 DIEVPESYSGELECIV----SPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTK 2284
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y+ V+ C+L++K
Sbjct: 2285 EDQGEYSF----VIDGKKTTCKLKMK 2306
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/285 (21%), Positives = 104/285 (36%), Gaps = 56/285 (19%)
Query: 202 PKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVID 260
P + W +G L + + + L I + + D G Y V AK ++
Sbjct: 2600 PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVE 2659
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF---TVL 317
+ I+K +++ L V T QD T L + + K QW VL
Sbjct: 2660 AVKIKK-----TLKNLTV---------TETQDAVFTVELTH----PNVKGVQWIKNGVVL 2701
Query: 318 ERYHPTTCTISDLIIGNSYSFRV-----FSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
E ++ G YS R+ E++ G H++ I KPK
Sbjct: 2702 ESNEKYAISVK----GTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPK- 2756
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D T+ + SV P + W +EI+ + K+R +S
Sbjct: 2757 -----------------DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVS 2798
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
E+ V L ++ SP D+G YT V+G+ ++C+ ++ H
Sbjct: 2799 ERKVHKLMLQNISPSDAGEYTA----VVGQ--LECKAKLFVETLH 2837
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ PL D ++ G + C V + K+ W +I+ + +R + LEI
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ P D G YT A N +G+ S L ++
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388
Score = 40.4 bits (93), Expect = 0.004
Identities = 19/61 (31%), Positives = 29/61 (47%)
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ W +++ + KY E GV L ++ + D G Y CK +N GE S L V
Sbjct: 25227 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286
Query: 472 K 472
K
Sbjct: 25287 K 25287
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/126 (24%), Positives = 44/126 (34%), Gaps = 6/126 (4%)
Query: 350 TSATVTKELAHIQKADIAAKPKGFIERDFSE----APSFTQPLADHTSTPGYSTQLFCSV 405
T T+E ++ D+ E AP F G S C V
Sbjct: 1000 TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV 1059
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+PKP + W K+ + + +Y+ + G C L I D+G YT N GE
Sbjct: 1060 GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGET 1119
Query: 464 SVDCRL 469
S L
Sbjct: 1120 SASASL 1125
Score = 40.0 bits (92), Expect = 0.005
Identities = 41/151 (27%), Positives = 63/151 (41%), Gaps = 11/151 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L L D++ SVT+ W+ P G + Y++E RE + +
Sbjct: 14494 DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEK-REATRKSYSTATTKCHKC 14552
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V L+ G ++ RV A + G G P +P+ + EAP P L I +
Sbjct: 14553 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV---KASEAPS--PPDSLNIMDITK- 14606
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
TV+L P KPK G+ +++QR
Sbjct: 14607 -STVSLAWP---KPKHDGGSKITGYVIEAQR 14633
Score = 39.3 bits (90), Expect = 0.008
Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR---VSMRTGDQDSILFIRSAQR 238
Q+ + G T + G P P+ +W +G + + V + D + L I + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 239 SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL 276
++SGRY L +A + ++LV + PP+ ++ L
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110
Score = 38.5 bits (88), Expect = 0.014
Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 26/144 (18%)
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSIL 231
P+ +P + + Y VGE V + P+P TW +G ++ GD D
Sbjct: 25318 PEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIKPGDNDK-- 25365
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT--- 288
+ SD G Y+LT+ + A ++ K G S C A L T
Sbjct: 25366 --KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS---------CKAKLTVTLHP 25414
Query: 289 PPQDTGNTELLGYMVQKADKKTGQ 312
PP D+ + ++ A+ + GQ
Sbjct: 25415 PPTDSTLRPMFKRLLANAECQEGQ 25438
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 1/97 (1%)
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE-QG 435
D + P F + LA+ G S V P P + W K+ + P + E
Sbjct: 25418 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 25477
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
L IR P D+G Y A N G S L+V+
Sbjct: 25478 YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Score = 37.7 bits (86), Expect = 0.023
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 4/80 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
GE+ G+P P TW G L S R + T S I S Q SD G Y +
Sbjct: 26203 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY--S 26260
Query: 248 VRVEDLEAKAVIDI-LVIEK 266
V VE+ E K + L I+K
Sbjct: 26261 VVVENSEGKQEAEFTLTIQK 26280
Score = 36.6 bits (83), Expect = 0.051
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTC 325
PG P + V + + W P+ G + + GY ++ D + +W V + T
Sbjct: 9945 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10004
Query: 326 TIS----DLIIGNSYSFRVFSENLCGLSTSA 352
+S LI G+ Y FRV++ N G+ ++
Sbjct: 10005 GVSYKVTGLIEGSDYQFRVYAINAAGVGPAS 10035
Score = 36.6 bits (83), Expect = 0.051
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PP D P P + T ++ S+ V W P+ G + Y++E + W+ + +
Sbjct: 15282 PP--DPPKNPEVTT---ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 15336
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPA 157
+ + V L G ++ R+ A ++AG P+
Sbjct: 15337 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15369
Score = 35.8 bits (81), Expect = 0.088
Identities = 18/64 (28%), Positives = 30/64 (46%)
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P + W+ + ++ + R ++E G C+L+ DSG+ TC+A N G
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745
Query: 469 LEVK 472
L VK
Sbjct: 1746 LIVK 1749
Score = 35.8 bits (81), Expect = 0.088
Identities = 26/104 (25%), Positives = 43/104 (41%)
Query: 370 PKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR 429
P F P F + +++ + G L +V PKPKI W N + + + Y+
Sbjct: 3570 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3629
Query: 430 ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
+ + +L I D G YTC A N G+ L++ +
Sbjct: 3630 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3673
Score = 35.8 bits (81), Expect = 0.088
Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 3/134 (2%)
Query: 42 EQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGR 99
E + + +A P ++P A S +PS P + + + W PE G
Sbjct: 22837 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22896
Query: 100 LGLQGYVLELCREGASEWVPVSARPMMV-TQQTVRNLALGDKFLLRVSAVSSAGAGPPAM 158
+ Y+++ + + W V+ ++ T+ V +L G + RV+AV++AG P+
Sbjct: 22897 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22956
Query: 159 LDQPIHIRENIEAP 172
I RE P
Sbjct: 22957 ASNFISCREPSYTP 22970
Score = 35.8 bits (81), Expect = 0.088
Identities = 54/291 (18%), Positives = 98/291 (33%), Gaps = 34/291 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + Q KP + W HNG L +S ++ L I DSG Y
Sbjct: 26016 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRA- 26074
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
+ G S LDV G + + +D ++
Sbjct: 26075 --------------VCTNYKGEASDYATLDVTGGDYTTYASQRRD-----------EEVP 26109
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS------ENLCGLSTSATVTKELAHI 361
+ T E Y ++ + + +S V S E+L SA+ + A +
Sbjct: 26110 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26169
Query: 362 QKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
++ + K + A T+P + T G S + C P P + W++
Sbjct: 26170 EEKSLEEKSTTRKIKTTLAARILTKPRS-MTVYEGESARFSCDTDGEPVPTVTWLRKGQV 26228
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + +++ + + T EI D G Y+ N G+ + L ++
Sbjct: 26229 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279
Score = 35.0 bits (79), Expect = 0.15
Identities = 37/142 (26%), Positives = 56/142 (39%), Gaps = 14/142 (9%)
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
WF + H T+ T+ G ++ + L +S KEL+ + +
Sbjct: 5234 WFKNDAKLH-TSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKV------ 5286
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+E D P FT L D T+ L C V S + W K+ EI +PKY +
Sbjct: 5287 -LEAD----PYFTVKLHDKTAVEKDEITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIKA 5339
Query: 433 EQGVCTLEIRKPSPFDSGVYTC 454
+ L+I+K D G Y C
Sbjct: 5340 DGLRRILKIKKADLKDKGEYVC 5361
Score = 35.0 bits (79), Expect = 0.15
Identities = 63/289 (21%), Positives = 114/289 (39%), Gaps = 40/289 (13%)
Query: 173 KIRVPRHLRQTYIRQVGETV-NLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSI 230
K+R+ L+ T +++ E V N ++ +G +A W N A+ DS + + D
Sbjct: 6267 KLRIVVPLKDTRVKEQQEVVFNCEVNTEGA---KAKWFRNEEAIFDSSKYIILQKDLVYT 6323
Query: 231 LFIRSAQRSDSGRYELTVRVEDLE-AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L IR A D Y +++ E K+ +++V E+ +R+++ P
Sbjct: 6324 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE-----DLRIVE-----------P 6367
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPT---TCTISDLIIGNSYSFRVFSENLC 346
+D ++ +KK+ ++ + R + T T ++ N S+RV
Sbjct: 6368 LKD----------IETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHM 6417
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS-FTQPLADHTSTPGYSTQLFCSV 405
E +I A + K E EAP+ F + L D T T + +F
Sbjct: 6418 LTIKDCGFPDEGEYIVTA---GQDKSVAELLIIEAPTEFVEHLEDQTVTE-FDDAVFSCQ 6473
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
+ K + W +N EI+ KY+ + + L I+ D Y C
Sbjct: 6474 LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 6522
Score = 34.7 bits (78), Expect = 0.20
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTC 454
G + + V P P+ W + +I + ++ + E G +L I +P DSG +T
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTV 1484
Query: 455 KAINVLGEASVDCRLEVKA 473
A N G +S+ L V+A
Sbjct: 1485 VAQNRAGRSSISVILTVEA 1503
Score = 34.7 bits (78), Expect = 0.20
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E FT+ LA+ + + +L C V + P ++IW K EI +Y L+E L
Sbjct: 6089 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 6147
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I+ D+G Y C+ L + D +++V AA
Sbjct: 6148 VIQNAHLEDAGNYNCR----LPSSRTDGKVKVHELAA 6180
Score = 34.3 bits (77), Expect = 0.26
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI--LFIRSAQRSDSGRY 244
GE+V L+ G P P TW + ++S + + Q I L IR A DSGR+
Sbjct: 911 GESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARLMIREAFAEDSGRF 967
Score = 34.3 bits (77), Expect = 0.26
Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P + + +VS SVT++WE P G + Y++E RE A T
Sbjct: 23164 DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK-REAAMRAFKTVTTKCSKT 23222
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ L G + RV + G G P + + E
Sbjct: 23223 LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 23261
Score = 33.9 bits (76), Expect = 0.33
Identities = 55/255 (21%), Positives = 94/255 (36%), Gaps = 49/255 (19%)
Query: 208 WTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
WT NG + RVS R +L I+ D G Y +T + K+V ++L+IE
Sbjct: 6394 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQD----KSVAELLIIEA 6449
Query: 267 PGP------PSSIRLLD--VWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
P ++ D V+ C + + + N G +++ K + +
Sbjct: 6450 PTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRN----GREIKEGKKYKFEKDGSIH 6505
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
R C + D E CG+ D ++ + F+E
Sbjct: 6506 RLIIKDCRLDDEC-----------EYACGVE---------------DRKSRARLFVE--- 6536
Query: 379 SEAP-SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
E P +P D PG +F + K ++ W++N M + K++ +SE +
Sbjct: 6537 -EIPVEIIRPPQDILEAPGADV-VFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIH 6594
Query: 438 TLEIRKPSPFDSGVY 452
L+I P D G Y
Sbjct: 6595 RLQICDIKPRDQGEY 6609
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 4/77 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G+T + G+P P+ W H+G + D + D L I A SDSG E
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG--EW 1482
Query: 247 TVRVEDLEAKAVIDILV 263
TV ++ ++ I +++
Sbjct: 1483 TVVAQNRAGRSSISVIL 1499
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G + + C V P+PK+ W N I+ + ++R + G+ L+I +D+G
Sbjct: 1809 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1867
Query: 456 AINVLGEASVDCRLEVK 472
A N G +LE++
Sbjct: 1868 AENPEGVIEHKVKLEIQ 1884
Score = 30.4 bits (67), Expect = 3.7
Identities = 63/326 (19%), Positives = 120/326 (36%), Gaps = 54/326 (16%)
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T ++L++ D +RV A+ + +L+ + + Q Y +
Sbjct: 5614 TFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKL------------QDYTGVEKD 5661
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
V LQ P W +G + S+ ++ + +L ++ A +SD G+Y
Sbjct: 5662 EVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCG 5720
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG-YMVQKAD- 307
+ K I+ I+ P S+ +++ + + N +L G ++Q D
Sbjct: 5721 TDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDC 5780
Query: 308 --KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ-KA 364
K+ G+ I L++ N C L + V + A+++ A
Sbjct: 5781 EIKEEGK--------------IHSLVLHN-----------CRLDQTGGVDFQAANVKSSA 5815
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
+ KP+ +PL D T T G + C + P ++K K +++
Sbjct: 5816 HLRVKPR---------VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGK-KLEP 5865
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSG 450
+ K SE V TL +R D+G
Sbjct: 5866 SDKVVPRSEGKVHTLTLRDVKLEDAG 5891
Score = 30.4 bits (67), Expect = 3.7
Identities = 34/160 (21%), Positives = 60/160 (37%), Gaps = 10/160 (6%)
Query: 13 SPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDV-- 70
S ET E EV+ SE+ E +PK T + + + +V
Sbjct: 9061 SKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHV 9120
Query: 71 -----PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSAR 123
PS P L + D+ + S ++W+ P G + YV++ +EW V+
Sbjct: 9121 EVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT-N 9179
Query: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
+ + + L ++ RV AV+ G D+ +
Sbjct: 9180 TAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 9219
Score = 30.0 bits (66), Expect = 4.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F +PL D + C + + K+ W K+ EI+ KY +S+ V L I K
Sbjct: 6004 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6062
Query: 444 PSPFDSGVYTCK 455
D Y+C+
Sbjct: 6063 CLLDDEAEYSCE 6074
Score = 29.3 bits (64), Expect = 8.2
Identities = 20/86 (23%), Positives = 33/86 (38%), Gaps = 4/86 (4%)
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
PL D G L C V + W N +I+ + + +A+ + L I +
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y ++G +C L V+
Sbjct: 2464 SDEGPYKL----IVGRVETNCNLSVE 2485
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 155 bits (392), Expect = 8e-38
Identities = 92/303 (30%), Positives = 156/303 (51%), Gaps = 15/303 (4%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
PA A + + +P PP + +TL DV+ +SV++SWE PE G + GY++E+
Sbjct: 15539 PAETAESVKASERPLPPGK--------ITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15590
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
+G+ +W + + VT+ T+ L G+++ RVSA + G P L P+ ++ +
Sbjct: 15591 QTKGSDKWATCAT--VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV 15648
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQD 228
P ++ L T+ GE + + +PF G+P P TW + L + RV+ + + +
Sbjct: 15649 IPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN 15705
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQW 287
S+L I+ A R D G Y + + EA ++++V++KPGPP+ +++ +V + L W
Sbjct: 15706 SLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSW 15765
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G + + Y+V+K D T W V TT L G Y FR+ +EN G
Sbjct: 15766 GPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYG 15825
Query: 348 LST 350
ST
Sbjct: 15826 KST 15828
Score = 155 bits (392), Expect = 8e-38
Identities = 92/291 (31%), Positives = 146/291 (50%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A + + PS P +TL DVS +S ++ WE PE G + GYV+E+ +G +W V
Sbjct: 17706 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17765
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ V V L+ G ++ RV A + G P +L P+ ++ P +++P +
Sbjct: 17766 AESK--VCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFN- 17822
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
TY Q GE + ++IP G+P+P +W +G L + RV++ ++L I+ +
Sbjct: 17823 --TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKD 17880
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTEL 298
D G+Y +T A + ++V+EKPGPP +R +V + W PP TG ++
Sbjct: 17881 DFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQI 17940
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+V+K D T W V TT I+ L G Y FR+F+EN G S
Sbjct: 17941 SNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 17991
Score = 155 bits (392), Expect = 8e-38
Identities = 96/325 (29%), Positives = 162/325 (49%), Gaps = 9/325 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR-PMMV 127
D P P + + D + SS+T+ W P G + GYV+E+ + EW VS + +
Sbjct: 20668 DPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRT 20727
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ V NL G + RVSAV+ AG G P +++P+ ++ +EAP+I + LR + I +
Sbjct: 20728 TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAK 20787
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRSDSGRYEL 246
GE V + IPF+G+P P TW + L S R S+ D S+L I R+D+G+Y L
Sbjct: 20788 AGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYIL 20847
Query: 247 TVRVEDLEAK-AVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
T+ E K + + + V++ P +++ V L W PP G + ++ Y+++K
Sbjct: 20848 TIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEK 20907
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
D W V + T+ + DL + FRV +EN G+ T+ ++ A+
Sbjct: 20908 RDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP---VKAAE 20964
Query: 366 IAAKPKGFIERDFSEAP---SFTQP 387
+ A + +D ++ S+T+P
Sbjct: 20965 VPAPIRDLSMKDSTKTSVILSWTKP 20989
Score = 154 bits (389), Expect = 2e-37
Identities = 121/445 (27%), Positives = 189/445 (42%), Gaps = 28/445 (6%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V KP A P A +P+PP LT D + SSV + WEPP + G +
Sbjct: 6776 VGKPSAATPFVKVADPIERPSPPVN--------LTSSDQTQSSVQLKWEPPLKDGGSPIL 6827
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
GY++E C EG W+ + + + V L G+K+L RVSA + AG P+ + P+
Sbjct: 6828 GYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPL 6887
Query: 164 HIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSM 222
+ P + + + V + + +P G P+P ATW L++ RV M
Sbjct: 6888 TADDAFVEPTMDLSAFKDGLEVI-VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKM 6946
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
+T + L I ++RSD G Y L + ID+ VI +P P ++ D+ +
Sbjct: 6947 KTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDS 7006
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP D G + L GY+V+K + W V++ T+ DL+ G Y F+V +
Sbjct: 7007 VHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCA 7066
Query: 343 ENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
N CG A V + + A + P+ RD + F D G S
Sbjct: 7067 RNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL--TWDPPKNDGGSRIKG 7124
Query: 403 CSVRASPKPKIIWM-------KNKMEIQGNP-------KYRALSEQGVCTLEIRKPSPFD 448
V P+ W+ + KME+ G + +AL+ QG + +P+
Sbjct: 7125 YIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGAS--KPSRPTEEI 7182
Query: 449 SGVYTCKAINVLGEASVDCRLEVKA 473
V T +A + + + L VKA
Sbjct: 7183 QAVDTQEAPEIFLDVKLLAGLTVKA 7207
Score = 154 bits (388), Expect = 2e-37
Identities = 82/278 (29%), Positives = 141/278 (50%), Gaps = 1/278 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P ++ + D S ++V++ W P G + + GY++E+C+ +W V+A + T+
Sbjct: 21757 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRY 21816
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV +L G+++ RVSA++ AG G + I + + AP++ + + +QT++ + G
Sbjct: 21817 TVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGA 21876
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
++ L I +QG+P P A W+ L S R + T D S L + + R+D+G+Y LTV
Sbjct: 21877 SIRLFIAYQGRPTPTAVWSKPDSNL-SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVEN 21935
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
+ V++ PGPP I DV +A L W P G + Y+V+K +
Sbjct: 21936 NSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASR 21995
Query: 311 GQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
W + E+ ++DL G Y FRV + N G+
Sbjct: 21996 RSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGV 22033
Score = 153 bits (386), Expect = 4e-37
Identities = 88/291 (30%), Positives = 151/291 (51%), Gaps = 7/291 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE P P +TL DV+ ++ T+ WE PE G + GYV+E+ +G+ +W
Sbjct: 18790 TEPVKVSEP-PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-- 18846
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + T+ L G++++ RV+AV+ G P L P+ R+ P + +P H
Sbjct: 18847 TCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH- 18905
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
T+ + E + + +PF+G+P+ W +G L ++ RV++ + + L I+ A +
Sbjct: 18906 --TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKE 18963
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
D G YEL V I I+V+++PGPP IR+ +V + + W PP+ G ++
Sbjct: 18964 DVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQIS 19023
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
Y+V+K + + W V + T+ I L G+ Y FRV +EN G S+
Sbjct: 19024 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSS 19074
Score = 152 bits (384), Expect = 6e-37
Identities = 89/283 (31%), Positives = 147/283 (51%), Gaps = 7/283 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
+VP P +T+DDV+ +SV++SW PE G + Y++E+ + + +W + +
Sbjct: 16632 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSL-- 16689
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
Q + NL G+++L RV AV+ G P L PI ++ + P ++ +Y QV
Sbjct: 16690 QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAF---SSYSVQV 16746
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + +++P G+PKP TWT +G L + R+++ + L I+ + D G+Y +T
Sbjct: 16747 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 16806
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
V + A I+I+ ++KP PP ++ DV + L W PP TG ++ Y+VQK
Sbjct: 16807 VANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKR 16866
Query: 307 DKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D T W V TT ++ L G Y FR+F+EN G S
Sbjct: 16867 DTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 16909
Score = 149 bits (375), Expect = 7e-36
Identities = 90/292 (30%), Positives = 144/292 (49%), Gaps = 2/292 (0%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T A +VP P L + DV+ S+VT++WE P G L GYVLE C+ G W+ V
Sbjct: 23128 TSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV 23187
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
V + TV +L G+++L R+ A + G P + +++ P I +
Sbjct: 23188 VTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 23247
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++T G V L IP G+P P A+W G L +S+RV++ T + + L IR
Sbjct: 23248 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 23307
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G Y L ++ I +++++KPGPP+ I++ ++ + + W PP+ G L
Sbjct: 23308 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 23367
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
GY+V++ D W V E +T + L GN Y FRV + N G+ +
Sbjct: 23368 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 23419
Score = 145 bits (367), Expect = 6e-35
Identities = 109/371 (29%), Positives = 175/371 (47%), Gaps = 16/371 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P SE PS P L + D++ S+V+++W P+ G + GYV+E R+G+ +W +
Sbjct: 14459 TEPVKASE-APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14517
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + + VRNL G+++ +V AV+SAG P +P+ ++E P++ +
Sbjct: 14518 TT--VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRE-SRPVIVKEQTMLPELDLRGIY 14574
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++ I + G+ + ++IP G+PKP TW L +QRV+ T +IL I RS
Sbjct: 14575 QKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRS 14634
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
DSG Y LT R E VI I V + PGPP+ I+ +V W PP++ G +
Sbjct: 14635 DSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 14694
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y+V+ + W + TT + L G Y FRV ++N G+ TSA +
Sbjct: 14695 SNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIV 14754
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ +D S S+ +PL+D G S L V + I+W
Sbjct: 14755 ANYPFKVPGPPGTPQVTAVTKD-SMTISWHEPLSD-----GGSPILGYHVERKERNGILW 14808
Query: 416 MK-NKMEIQGN 425
+K + GN
Sbjct: 14809 QTVSKALVPGN 14819
Score = 145 bits (366), Expect = 8e-35
Identities = 95/331 (28%), Positives = 159/331 (48%), Gaps = 19/331 (5%)
Query: 49 APAPQAP---TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
AP+P +P T KP PP P +L D S SS++++W P G + GY
Sbjct: 15242 APSPTSPFYKACDTVFKPGPPGN-----PRVL---DTSRSSISIAWNKPIYDGGSEITGY 15293
Query: 106 VLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E+ EW V+ + T T+ L ++ +R+ A++S G G PA++
Sbjct: 15294 MVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPK 15353
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHN-GHALDSQRVSMR 223
+ + P+I + LR+ + T+ L +P +G+P P+ W + G +LD + S+
Sbjct: 15354 AEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIE 15411
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ ++L + + R DSG+Y LTV A +++ V++ PGPP +++ +V +
Sbjct: 15412 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15471
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L W PP G +++ Y+V+K + + TV H T+ + L G SY FRV +E
Sbjct: 15472 TLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAE 15531
Query: 344 NLCGLSTSATVTKELAHIQKADIAAKPKGFI 374
N G+ A E A KA P G I
Sbjct: 15532 NEYGIGLPA----ETAESVKASERPLPPGKI 15558
Score = 144 bits (362), Expect = 2e-34
Identities = 86/282 (30%), Positives = 140/282 (49%), Gaps = 4/282 (1%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P L + +V+ ++VT++W PP+ G + YVLE G ++ V+ ++ +
Sbjct: 10219 VPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 10278
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV+ L GD + RVSAV+ G G P+ +PI ++ + P + + R +VG
Sbjct: 10279 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHL--DFRDKLTIRVG 10336
Query: 190 ETVNLQIPFQGKPKPQATW-THNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
E L + GKPKP+ +W L+ R ++T L A+RSDSG+Y + V
Sbjct: 10337 EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV 10396
Query: 249 RVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
K + V+++PGPP + +V + W PP D G +++ Y+++K +
Sbjct: 10397 ENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKE 10456
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
W V TTC +S L+ G Y FR+ +ENL G+S
Sbjct: 10457 VGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGIS 10498
Score = 144 bits (362), Expect = 2e-34
Identities = 84/305 (27%), Positives = 146/305 (47%), Gaps = 10/305 (3%)
Query: 54 APTASTATKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A A + KP+ PS+ + P P + D + +SV+++W PE G + GY
Sbjct: 23511 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 23570
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165
++E+ + EW + P + + T+ +L G ++ RV A ++ G G PA + + +
Sbjct: 23571 LIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23630
Query: 166 RENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG 225
E +E P + ++ + G + L IP +GKP P WT G + S+R + T
Sbjct: 23631 TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI-SKRAMIATS 23689
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
+ + L I+ A R DSG Y+L + + + I + VI P P + D+ +
Sbjct: 23690 ETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR 23749
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
+ W PP D G ++LGY++++ + W+T+ R T+ + L Y FRV +EN
Sbjct: 23750 VSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 23809
Query: 345 LCGLS 349
G+S
Sbjct: 23810 QFGIS 23814
Score = 140 bits (354), Expect = 2e-33
Identities = 81/280 (28%), Positives = 142/280 (50%), Gaps = 2/280 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
VP P + D +++S+ ++W+PP+ G ++GY++E C G+ +WV P+ T+
Sbjct: 7090 VPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETK 7148
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
V L G + RV A++ GA P+ + I + EAP+I + L + G
Sbjct: 7149 MEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAG 7208
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
+ L GKP+P+ TWT L +R+++ + S + I ++RSD+G Y +
Sbjct: 7209 TKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEA 7268
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
A AV+++ V++KPGPP++ + DV + L W PP+D G +++ Y+V++
Sbjct: 7269 VNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRAT 7328
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ W + T + LI Y FRV +EN+ G+
Sbjct: 7329 DSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGV 7368
Score = 140 bits (354), Expect = 2e-33
Identities = 91/313 (29%), Positives = 146/313 (46%), Gaps = 9/313 (2%)
Query: 54 APTASTATKPAPPSEDV-------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYV 106
A A+ K +PPS+ P P + + D SS+++ + WEPP G + GY
Sbjct: 8481 AENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYF 8540
Query: 107 LELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR 166
++ G +EW + + + V Q TV+ + G + LRVSAV++AG GPP QP+ +
Sbjct: 8541 VDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE-TQPVTVA 8599
Query: 167 ENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGD 226
E E P + + ++ G+T+ + G+P P WT LD RV +
Sbjct: 8600 EPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVG 8659
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
S L I+ A R D GRY +T A + V + PGP ++ + L
Sbjct: 8660 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8719
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W+ P+D G +E+ G+++++ D K W +E + C I+ L+ G Y FRV ++N
Sbjct: 8720 WSDPEDDGGSEITGFIIERKDAKMHTWRQPIET-ERSKCDITGLLEGQEYKFRVIAKNKF 8778
Query: 347 GLSTSATVTKELA 359
G + LA
Sbjct: 8779 GCGPPVEIGPILA 8791
Score = 140 bits (353), Expect = 3e-33
Identities = 88/305 (28%), Positives = 147/305 (48%), Gaps = 7/305 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
TK + PS P L + +S SV+++W PE G + YV+E +G WV
Sbjct: 19868 TKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC 19927
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ T V L ++ RV A + AG P L P+ I+E +E P+I +
Sbjct: 19928 AVAKS--THHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFP 19985
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRS 239
T + G + + IP GKP P+ T + +G L + R + ++ + ++ + +
Sbjct: 19986 SHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA 20045
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+GRYE+T KA I+I+V+++PGPP+ + + D+ + L+W PP+ G +++
Sbjct: 20046 DAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQV 20105
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS---TSATVT 355
Y++ K + T W V T + L G Y FR+ +EN G+S SA VT
Sbjct: 20106 TNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVT 20165
Query: 356 KELAH 360
+L +
Sbjct: 20166 VKLPY 20170
Score = 139 bits (351), Expect = 4e-33
Identities = 86/300 (28%), Positives = 149/300 (49%), Gaps = 6/300 (2%)
Query: 61 TKPAPPSED---VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEW 117
T P +ED +PS P + D +++T++W P G + GY +E + ++W
Sbjct: 19574 TSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW 19633
Query: 118 VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVP 177
S + + T+ T+ L G +++ RV +V+ GA P+ P +E E P +
Sbjct: 19634 -KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDID 19692
Query: 178 RHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQ 237
+R+T I + G + + +PF+G+P P W+ L + R + T D + L I +A
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTSLTIENAN 19751
Query: 238 RSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
R+DSG+Y LT++ A + + V++ PGPP++I + DV +A L W P++ G
Sbjct: 19752 RNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAP 19811
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKE 357
+ Y ++K + W +V + + +++L G Y FRV EN G+ A TKE
Sbjct: 19812 VKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKE 19870
Score = 138 bits (347), Expect = 1e-32
Identities = 87/299 (29%), Positives = 144/299 (48%), Gaps = 14/299 (4%)
Query: 61 TKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+ PSE D P P+ L +++ +VT+ W PE G + Y++E
Sbjct: 14845 SKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKITSYIVEKRDL 14901
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEA 171
W+ + ++ + TV L + RV A ++AGA PP+ I R+++EA
Sbjct: 14902 PNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEA 14961
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSI 230
PKI+V + T I + GE L+ G+P P W+ +G L+ + ++ ++ D +
Sbjct: 14962 PKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN 15021
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTP 289
L + + R DSG Y LT AK + ++ V+++PGPP + + +V L W P
Sbjct: 15022 LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15081
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P D G ++ Y+VQK + W V T ++ L+ GN Y FRV + N G+
Sbjct: 15082 PLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15140
Score = 138 bits (347), Expect = 1e-32
Identities = 86/314 (27%), Positives = 145/314 (46%), Gaps = 10/314 (3%)
Query: 44 VPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQ 103
V +P P+ P PPS + D S SSV+++W P G ++
Sbjct: 18487 VGEPSEPSVFYRACDALYPPGPPSNP--------KVTDTSRSSVSLAWSKPIYDGGAPVK 18538
Query: 104 GYVLELCREGASEWVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
GYV+E+ A EW + + +Q TV L ++ R+ A++S G G PA L
Sbjct: 18539 GYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGS 18598
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM 222
+ +E IE P+I + LR+ + + T+ L + +G+P+P+ W + + R +
Sbjct: 18599 VVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKW-EKAEGILTDRAQI 18657
Query: 223 RTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCN 282
++L I + R DSGRY LT+ A +++ V++ P P ++ + +V +
Sbjct: 18658 EVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDS 18717
Query: 283 AALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
L W PP G ++ Y+V+K + + T+ TT I +L G SY FRV +
Sbjct: 18718 VTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 18777
Query: 343 ENLCGLSTSATVTK 356
N G+ A T+
Sbjct: 18778 SNEYGIGLPAETTE 18791
Score = 137 bits (344), Expect = 3e-32
Identities = 85/320 (26%), Positives = 153/320 (47%), Gaps = 10/320 (3%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P + S K A PS P + D + S +++W P G L + GYV+E +
Sbjct: 14160 PSEASDSVLMKDAAYPPGPPSNP---HVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQK 14216
Query: 112 EGASEWVP-VSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G W+ + + +TQ V +L +K+ R+SA++ AG G PA++ + I E
Sbjct: 14217 VGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-VEIVEREM 14275
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
AP + LR+T + + G ++ + +P +G+P P+ TWT + L + R ++ + ++
Sbjct: 14276 APDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN-RANIENTESFTL 14334
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I R D+G++ +T+ + +++ V++ PGP ++R D+ + L W P
Sbjct: 14335 LIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLP 14394
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLST 350
G + + Y+V+K + + T + H T ++ L G Y FRV +EN G+
Sbjct: 14395 LIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14454
Query: 351 SATVTKELAHIQKADIAAKP 370
T+ + KA A P
Sbjct: 14455 PTETTEPV----KASEAPSP 14470
Score = 135 bits (340), Expect = 8e-32
Identities = 87/319 (27%), Positives = 146/319 (45%), Gaps = 11/319 (3%)
Query: 63 PAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P+PPS+ V PS P+ D + +SV ++W+PP G + GY++E + G
Sbjct: 10600 PSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGD 10659
Query: 115 SEWVPVSARPMMV--TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
EW + P T+ V L G + RV AV++AG PA + +P+ +++ +E P
Sbjct: 10660 EEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPP 10719
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
++ + ++ + +VG+T+ L +G P P+ TW + + + S L
Sbjct: 10720 ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT-KARIDVTPVGSKLE 10778
Query: 233 IRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
IR+A D G Y LTV + +LV++KPGPP + + ++ + L W P D
Sbjct: 10779 IRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLD 10838
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
G + + Y+V++ D + QW + + L GN Y FRV +EN G
Sbjct: 10839 DGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFV 10898
Query: 353 TVTKELAHIQKADIAAKPK 371
K + + PK
Sbjct: 10899 ETPKPIKALDPLHPPGPPK 10917
Score = 135 bits (340), Expect = 8e-32
Identities = 83/299 (27%), Positives = 153/299 (51%), Gaps = 2/299 (0%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ++ A + P P + D + SSV++SW P G + GY++E+ R
Sbjct: 13073 PGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKR 13132
Query: 112 EGASEWVPVSA-RPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
+ WV + + + T+ V L ++ RV AV+ G P+ + + ++ +
Sbjct: 13133 ADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILI 13192
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRTGDQDS 229
P+ + LR+T I + G T+ L +P +G+P P+ TW+ N + D + +++ D D+
Sbjct: 13193 PPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDT 13252
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L + + D+G+Y LT+ + + I + V++ PGPP ++ + ++ +A + W P
Sbjct: 13253 FLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEP 13312
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P G + ++ Y+VQK D + W TV T+ +++L G SY FRVF+EN G+
Sbjct: 13313 PIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGI 13371
Score = 134 bits (338), Expect = 1e-31
Identities = 85/299 (28%), Positives = 151/299 (50%), Gaps = 10/299 (3%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P PT + + P P PS PL L + D + ++W+PPE+ G + GY +E+C
Sbjct: 7772 PSEPTEILSIEDPTSP----PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMC 7827
Query: 111 REGASEWVPVSARPMMVTQQTVRNLALGDK-FLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
G +W+ V++RP+ + V + DK ++LRV AV++ G P+ + + + ++
Sbjct: 7828 PVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPD 7887
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQD 228
P I + H I GE +++ +PF+ P P +W +G + S R++M+
Sbjct: 7888 CKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHIS 7944
Query: 229 SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+ L + + R+D+G Y +T+ + A A I++ VI PGP I+ D+ + L W
Sbjct: 7945 AHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWE 8004
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
PP+ G T +L Y++++ + + V+ + + T+ DLI Y FRV + N G
Sbjct: 8005 PPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8063
Score = 134 bits (338), Expect = 1e-31
Identities = 86/307 (28%), Positives = 140/307 (45%), Gaps = 11/307 (3%)
Query: 46 KPQAPAPQAPTAS-TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQG 104
K + P PT TA P P P P ++ DV+ S+V++ W P+ G + G
Sbjct: 12674 KAGSSPPSKPTEYVTARMPVDP----PGKPEVI---DVTKSTVSLIWARPKHDGGSKIIG 12726
Query: 105 YVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK--FLLRVSAVSSAGAGPPAMLDQP 162
Y +E C+ +WV + P + Q+ L +K + R A ++ PP+ P
Sbjct: 12727 YFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12786
Query: 163 IHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALD-SQRVS 221
+ I P+I + ++ + G V L GKP P +W +G L ++ +
Sbjct: 12787 VTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK 12846
Query: 222 MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGC 281
M L + S R DSG Y +T A I + V++KPGPP+S+++ ++
Sbjct: 12847 MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSD 12906
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
A L W PP + G +E+ Y+V K + W V T+C++ LI G+ Y FR+
Sbjct: 12907 RAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRIC 12966
Query: 342 SENLCGL 348
+EN G+
Sbjct: 12967 AENKYGV 12973
Score = 134 bits (337), Expect = 2e-31
Identities = 111/426 (26%), Positives = 182/426 (42%), Gaps = 23/426 (5%)
Query: 48 QAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVL 107
+ P + P A P P P P L DV + V++ W P+R G + GY++
Sbjct: 10894 RGPFVETPKPIKALDPLHP----PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 10949
Query: 108 ELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E EG +W+ + + + V L G + RV A + G G P PI +E
Sbjct: 10950 EYQEEGTQDWIKF--KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTI-PIECQE 11006
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDS-QRVSMRTGD 226
+ P + + L + + + G TV +G P P A WT +G + + + ++ T +
Sbjct: 11007 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11066
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
S+L I++ R D+G Y++TV + + V++ PGPP+ I +LDV + +
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTI 11126
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W PP+D G + ++ Y+V+K D + W V T I L G Y FRV +EN
Sbjct: 11127 SWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 11186
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE---APSFTQPLADHTS-TPGY---- 397
G+ T +A K + P + D +E S+T P +D S GY
Sbjct: 11187 IGVGPPLDSTPTVAK-HKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMER 11245
Query: 398 --STQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
T + V +P + + + ++R +E + KPSP + C+
Sbjct: 11246 REVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAEN---LAGLSKPSPSSDPIKACR 11302
Query: 456 AINVLG 461
I G
Sbjct: 11303 PIKPPG 11308
Score = 133 bits (335), Expect = 3e-31
Identities = 99/424 (23%), Positives = 187/424 (44%), Gaps = 20/424 (4%)
Query: 41 EEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRL 100
E +V A P+ +T A P P + D + +S+T++W P G
Sbjct: 17393 EFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGS 17452
Query: 101 GLQGYVLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAML 159
+ GYV+E+C+ EW V+ + + VT+ + L ++ +RV A++ G G +
Sbjct: 17453 EILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSV 17512
Query: 160 DQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
+ + +EAP++ + LR+ + + G + + IPF+G+P P+ TW+ + +
Sbjct: 17513 PGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF-TDK 17571
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
V + G + L I + R+D+G+Y L + A + + V++ PGPP ++ + +V
Sbjct: 17572 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17631
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR 339
+A L W PP G ++ Y++ K + + V + T+ + +L G Y FR
Sbjct: 17632 KDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFR 17691
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
V +EN G+ V E KA P G + L D + T ++
Sbjct: 17692 VMAENEFGVG----VPVETVDAVKAAEPPSPPGKV------------TLTDVSQTS--AS 17733
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
++ +++ +M+ +G K+ ++E VC + S + KA N
Sbjct: 17734 LMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNE 17793
Query: 460 LGEA 463
G++
Sbjct: 17794 KGKS 17797
Score = 132 bits (332), Expect = 7e-31
Identities = 74/289 (25%), Positives = 139/289 (48%), Gaps = 11/289 (3%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT-- 128
P P + D + SS+++ W+PP + G ++GY++E+ EG ++W V+ ++T
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9267
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ V NL K+ RV AV+ AG P+ I + E P++ + + + +
Sbjct: 9268 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9327
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR---------VSMRTGDQDSILFIRSAQRS 239
G + + +G+P P+++W +G A + + + T + S++ I +RS
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
+G+Y +T + + + A + V++ PGPP +++ D+ + L W P D G +
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIK 9447
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
GY+++K W V TT + DL+ Y FRV +EN G+
Sbjct: 9448 GYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 9496
Score = 132 bits (332), Expect = 7e-31
Identities = 84/317 (26%), Positives = 143/317 (45%), Gaps = 3/317 (0%)
Query: 57 ASTATKPAPPSEDV-PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
AS + PA + + P P + D + SS + W PP + G + GY++E EG
Sbjct: 9909 ASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKE 9968
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIR 175
EW + + T+ V L G + RV AV+ AG G P + I +++ + +P ++
Sbjct: 9969 EWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQ 10028
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRS 235
+ +R + G + + GKP P TW N L Q ++ T S + I++
Sbjct: 10029 LDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL-PQEATIETTAISSSMVIKN 10087
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTG 294
QRS G Y L + E E K I + V++ PGP + L ++ + L W P+D G
Sbjct: 10088 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 10147
Query: 295 NTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATV 354
+ + Y+++K + W V T+ LI G +Y FR+ +EN G+
Sbjct: 10148 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVET 10207
Query: 355 TKELAHIQKADIAAKPK 371
++ L + + +P+
Sbjct: 10208 SEALVIREPITVPERPE 10224
Score = 131 bits (329), Expect = 2e-30
Identities = 90/314 (28%), Positives = 138/314 (43%), Gaps = 14/314 (4%)
Query: 52 PQAPTASTATKPAPPSEDV--PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P PT KP S+ + P P L + +++ +S T++W PP R G + GY+
Sbjct: 12283 PGVPT--DVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSY 12340
Query: 110 CREG--ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
E A W S + V L G K+ RV+A ++ G P + +E
Sbjct: 12341 REEEQPADRWTEYSV--VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKE 12398
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHN-GHALDSQRVSMRTGD 226
+ PKI +P + + G+ + ++ GKP P W + S +++ D
Sbjct: 12399 QLLPPKILMPEQITI----KAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKAD 12454
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAAL 285
SIL I+ R DSG Y LT I ++V++ PGPP + D+ +L
Sbjct: 12455 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 12514
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
W P + G + + Y+V+K D G W T L T+C + LI G Y FRV +EN
Sbjct: 12515 SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12574
Query: 346 CGLSTSATVTKELA 359
G+S T K +A
Sbjct: 12575 FGISEPLTSPKMVA 12588
Score = 131 bits (329), Expect = 2e-30
Identities = 83/309 (26%), Positives = 146/309 (47%), Gaps = 12/309 (3%)
Query: 46 KPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
+P P+ KP PP+ P ++ D++ SSV +SW P G +QGY
Sbjct: 16324 EPSPPSAYQKACDPIYKPGPPNN-----PKVI---DITRSSVFLSWSKPIYDGGCEIQGY 16375
Query: 106 VLELCREGASEWVPVSARP-MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
++E C EW + + T V L ++ R+ A++ AG G A + PI
Sbjct: 16376 IVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPII 16435
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMR 223
+ E +EAP I + LR+ + G ++ L +P +G+P P+ W +G D+ + +
Sbjct: 16436 VEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVT 16495
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
+ +L + R DSG+Y LT+ A + + V++ P PP ++++ ++ +
Sbjct: 16496 SSFTSLVL--DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSV 16553
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
++ W PP G +++ Y+V+K + + V+ H + I L G SY FRV +E
Sbjct: 16554 SITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16613
Query: 344 NLCGLSTSA 352
N G+ A
Sbjct: 16614 NEYGIGLPA 16622
Score = 130 bits (326), Expect = 3e-30
Identities = 82/290 (28%), Positives = 144/290 (49%), Gaps = 7/290 (2%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+ A + P + L + VS SS ++ W+ P G + GYV++ E ++W V
Sbjct: 13377 TRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTE-ENKWQRV 13435
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ Q + ++L G ++ RVSA + G G P+ + + R+++ AP + +
Sbjct: 13436 MKS--LSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDVVAPDLDLKGLP 13491
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFIRSAQRS 239
Y+ + L+IP +GKP P +W L + RVS+ + ++ L + Q+S
Sbjct: 13492 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13551
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTEL 298
D+G+Y +T++ + I I V+ KPG P+ I+ +V L+W PP+D G +E+
Sbjct: 13552 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13611
Query: 299 LGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Y+++K D +W T TT ++ L G Y+FRV +EN G+
Sbjct: 13612 TNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13661
Score = 129 bits (325), Expect = 4e-30
Identities = 91/314 (28%), Positives = 152/314 (48%), Gaps = 15/314 (4%)
Query: 52 PQAPTASTATK-PAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC 110
P P+ K P P P P + D + S+T+ W P G + GYV+E+
Sbjct: 11984 PSLPSRPVVAKDPIEP----PGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMR 12039
Query: 111 REGASE-----WVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ A W +A +V ++ TV +L ++ RV A + G G PA L + I
Sbjct: 12040 PKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 12099
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
+E +E P+I + +R+ I + G + L +G+P P+ TW G ++ +
Sbjct: 12100 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL 12159
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
D + L I ++ R DSG+Y LT+ E +++ V++ PGP S +++ DV +
Sbjct: 12160 VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCH 12219
Query: 285 LQWTPPQDTGNTELLGYMVQK--ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS 342
+ W PP++ G +++ Y+V+K AD+KT W TV T+ +++L+ GN Y FRV +
Sbjct: 12220 VSWAPPENDGGSQVTHYIVEKREADRKT--WSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12277
Query: 343 ENLCGLSTSATVTK 356
N G V K
Sbjct: 12278 VNEYGPGVPTDVPK 12291
Score = 124 bits (310), Expect = 2e-28
Identities = 79/279 (28%), Positives = 135/279 (48%), Gaps = 5/279 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR-PMMVTQ 129
PSAP ++ D + S++++W P G + GYVLE+ + +W V + T+
Sbjct: 22848 PSAPRVV---DTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 22904
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
TV +L +G K+ RV+AV+ G + I E IE P + + L++T + G
Sbjct: 22905 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAG 22964
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
++ L + G+P P TW+ G L S R + T + S+L + R D+G+Y +
Sbjct: 22965 ASLRLMVSVSGRPPPVITWSKQGIDLAS-RAIIDTTESYSLLIVDKVNRYDAGKYTIEAE 23023
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ + A + + V + PGP S+++ +V + + W P G + Y+V+K +
Sbjct: 23024 NQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAA 23083
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ TV + T IS L+ G Y FRV EN+ G+
Sbjct: 23084 MRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23122
Score = 123 bits (309), Expect = 3e-28
Identities = 83/281 (29%), Positives = 129/281 (45%), Gaps = 4/281 (1%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P+ P L + D S SS ++W P+ G + GY+LE+ ++G+ WV +
Sbjct: 22049 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTF-- 22106
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
TV L ++ RV A + AG P + I+E P + Q + G
Sbjct: 22107 TVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGS 22166
Query: 191 TVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ +P G+P P+ TW L ++ RVS+ T + L ++ + R DSGRY LT+
Sbjct: 22167 PFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLE 22226
Query: 250 VEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ ++VI +PGP + I + V + L W P+D G TE+ Y+V+K +
Sbjct: 22227 NTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRES 22286
Query: 309 KTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
T W V T ++ L YSFRV SEN G+S
Sbjct: 22287 GTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVS 22327
Score = 123 bits (308), Expect = 4e-28
Identities = 90/304 (29%), Positives = 137/304 (45%), Gaps = 10/304 (3%)
Query: 54 APTASTATKPAPPSE-----DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
A A+ KP+ PSE D P + + D+S +SV++SW+ P G + GY++E
Sbjct: 20249 AENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE 20308
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRE 167
W S + TQ + L ++ RV A ++ G+ P+ + PI +
Sbjct: 20309 RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCID 20368
Query: 168 NIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM--RTG 225
+ P I +P + + G +V L+ GKP P W + L + + T
Sbjct: 20369 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTT 20428
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAA 284
D SIL I+ A R +SG YEL +R A A I + +++KPGPP I V
Sbjct: 20429 DLASIL-IKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKIT 20487
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L W PP D G ++ Y+V+K + W V E T + +I GN Y FRV + N
Sbjct: 20488 LLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVN 20547
Query: 345 LCGL 348
G+
Sbjct: 20548 KYGI 20551
Score = 122 bits (307), Expect = 5e-28
Identities = 110/421 (26%), Positives = 172/421 (40%), Gaps = 35/421 (8%)
Query: 67 SEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMM 126
S + P PL DD+ SV VSW PP G + GY+LE + W + +R +
Sbjct: 23730 SPNSPEGPL--EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VR 23786
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK--IRVPRHLRQT- 183
T V+ L ++ RVSA + G P ++P+ + + P+ P L T
Sbjct: 23787 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTK 23846
Query: 184 ------YIRQVGETVNLQIPFQGKPKPQAT--WT-HNGHALDSQRVSMRTGDQDSILFIR 234
+ R + + + + K +T W HN + + ++ D+ R
Sbjct: 23847 SSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFR 23906
Query: 235 SAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++D G E + E + K D KP P + +L + + LQW P+ G
Sbjct: 23907 IIAQNDVGLSETSPASEPVVCKDPFD-----KPSQPGELEILSISKDSVTLQWEKPECDG 23961
Query: 295 NTELLGYMVQKADKKTGQWF-TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
E+LGY V+ W + ER TI L+ Y FRVF+EN GLS
Sbjct: 23962 GKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRR 24021
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKI 413
+ K + + EAP + + D T+ G + QL C + P P I
Sbjct: 24022 TAMSI----KTKLTS----------GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDI 24067
Query: 414 IWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
W + E+ + KY+ S+ TL + D GVYTC A N +GE +L ++A
Sbjct: 24068 KWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 24127
Query: 474 S 474
+
Sbjct: 24128 T 24128
Score = 120 bits (300), Expect = 4e-27
Identities = 72/270 (26%), Positives = 126/270 (46%), Gaps = 3/270 (1%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V + +T+ W P G + GY++E W+ S ++ TQ TV L ++
Sbjct: 17035 VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRY 17094
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AGA P+ PI ++ +E P+I + R T + GET L+ G
Sbjct: 17095 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 17154
Query: 201 KPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W ++ S R ++ D ++L ++ A R D G+Y L +
Sbjct: 17155 KPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPV 17214
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP +++ V +L W+PP G +++ Y+V+K + W V
Sbjct: 17215 NVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVAS 17274
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
+ ++ L+ GN Y FR+ + N G+
Sbjct: 17275 EVVTNSLKVTKLLEGNEYVFRIMAVNKYGV 17304
Score = 117 bits (293), Expect = 2e-26
Identities = 77/312 (24%), Positives = 140/312 (44%), Gaps = 13/312 (4%)
Query: 82 VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKF 141
V+ +SVT+ W+ P G + GY++E W+ S ++ T V L ++
Sbjct: 15953 VTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 16012
Query: 142 LLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQG 200
RV A ++AG P+ I R+ ++ P+I + + T + GE+ + G
Sbjct: 16013 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16072
Query: 201 KPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVI 259
KP P W L ++ R+ +++ D + L ++ A R DSG Y L + E +
Sbjct: 16073 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16132
Query: 260 DILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
++ V+++PGPP + + V L W PP G ++++ Y+V++ + W V
Sbjct: 16133 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 16192
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
+C ++ L+ GN Y+FR+ + N G+ ++ + AK F+ D
Sbjct: 16193 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP---------LESEPVVAK-NPFVVPDA 16242
Query: 379 SEAPSFTQPLAD 390
+AP T D
Sbjct: 16243 PKAPEVTTVTKD 16254
Score = 116 bits (291), Expect = 4e-26
Identities = 77/322 (23%), Positives = 147/322 (45%), Gaps = 13/322 (4%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+KP+P S+ + P P+ L D S + + W P G + GYV+E +
Sbjct: 11289 SKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKP 11348
Query: 113 GASEWVPVSARPMMVTQQTVR--NLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G ++W ++ + ++ Q R L G+++ R+ A + G G P L + + ++ +
Sbjct: 11349 GTAQWNRIN-KDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILH 11407
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
P++ + R +VG+T+ + +G+P+P TWT G L +RV +
Sbjct: 11408 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV 11467
Query: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L I+ A R+D G+Y ++ + A+ + V+++PGP ++++ +V N + W
Sbjct: 11468 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWEN 11527
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
P D G +E+ ++V+ W V ++L+ N Y FRV +EN G+
Sbjct: 11528 PLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGVG 11586
Query: 350 TSATVTKELAHIQKADIAAKPK 371
+ + I D +P+
Sbjct: 11587 PTIETKTPILAINPIDRPGEPE 11608
Score = 116 bits (290), Expect = 5e-26
Identities = 83/297 (27%), Positives = 140/297 (47%), Gaps = 14/297 (4%)
Query: 62 KPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
KP+ PSE D P P ++ +++ +SVT+ W P+ G L GY++E
Sbjct: 13763 KPSLPSEPVVALDPIDPPGKPEVI---NITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLP 13819
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAP 172
+ W+ + + TV +L G K+ R+ A ++AGA P+ + I ++ EAP
Sbjct: 13820 SKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 13879
Query: 173 KIRVPRHLRQTYIRQVGETVNLQ-IPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSI 230
I + ++ + G+T+ L I GKP P+++W+ G + ++ T S+
Sbjct: 13880 TIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSM 13939
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
L I+ A R D+G Y +T + + V++ PGPP + + +V A L WTPP
Sbjct: 13940 LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP 13999
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
+ G + + Y+++K + W V E + LI GN Y FRV + N G
Sbjct: 14000 LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14056
Score = 115 bits (288), Expect = 9e-26
Identities = 75/309 (24%), Positives = 133/309 (43%), Gaps = 36/309 (11%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P+ + + + ++ ++T++W+PP G + GY++E +G W + + +
Sbjct: 8083 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8142
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T + L G ++ RV A ++AG P+ P + I+APK+ LR + + G+
Sbjct: 8143 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKV----ILRTSLEVKRGD 8198
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTG------------------------- 225
+ L G P P TW + + + + + R
Sbjct: 8199 EIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLS 8258
Query: 226 -----DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWG 280
+S L +R + R D G Y + V + AKA + V++ PGPP + D+
Sbjct: 8259 IDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRK 8318
Query: 281 CNAALQWTPPQDTGNTELLGYMVQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSF 338
+ +W PP D G +E++ Y ++K D K +W V +++ LI G Y F
Sbjct: 8319 TSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLF 8378
Query: 339 RVFSENLCG 347
RV +EN G
Sbjct: 8379 RVRAENRFG 8387
Score = 115 bits (287), Expect = 1e-25
Identities = 87/321 (27%), Positives = 145/321 (45%), Gaps = 17/321 (5%)
Query: 54 APTASTATKPAPPSE--------DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
A ++ + P+ PS+ D P P + DV+ ++T+ W PP R G + GY
Sbjct: 21336 AENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGY 21392
Query: 106 VLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIH 164
+E R+G WV + + Q TV L+ GD++ R+ A ++ G PP+ I
Sbjct: 21393 SIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIM 21451
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT 224
R+ P + I + GE++ ++ QG+P P+ TW +G ++ +R++M
Sbjct: 21452 TRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNMEI 21510
Query: 225 GDQ--DSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRLLDVWGC 281
D + LF+R A R G Y + + AKA I + V + PG IR ++ G
Sbjct: 21511 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 21570
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVF 341
L W P + G + Y+++K + W + ++ + T LI GN Y FRV
Sbjct: 21571 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 21630
Query: 342 SENLCGLSTSATVTKELAHIQ 362
+ N G+ +A IQ
Sbjct: 21631 AVNKFGVGRPLDSDPVVAQIQ 21651
Score = 114 bits (284), Expect = 3e-25
Identities = 81/305 (26%), Positives = 136/305 (44%), Gaps = 7/305 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L + D + V + W P+ G Y +E +G+ +W V + T
Sbjct: 11602 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11661
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V + RV + G ++ + ++E+++ P + + L +
Sbjct: 11662 HYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVV-VKEDLQKPVLDLK--LSGVLTVKA 11718
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD---SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
G+T+ L+ +GKP P+ WT + A D S RV + T S + A+RSD G+Y
Sbjct: 11719 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11778
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
+T A + V++KPGP +++++DV + W PP+D G E+ Y+++K
Sbjct: 11779 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEK 11838
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ K W T T++ LI GN Y FRV +EN G + T +K + K D
Sbjct: 11839 CETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG-TGPPTESKPVIAKTKYD 11897
Query: 366 IAAKP 370
+P
Sbjct: 11898 KPGRP 11902
Score = 114 bits (284), Expect = 3e-25
Identities = 73/298 (24%), Positives = 141/298 (47%), Gaps = 12/298 (4%)
Query: 58 STATKPAPPSE--DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
S + +P P + D P P + +++ SV++ W P G + GY++E
Sbjct: 19176 SKSCEPVPARDPCDPPGQP---EVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDG 19232
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKI 174
W+ + + T V L ++ RV A ++A + P+ PI +++++E P++
Sbjct: 19233 RWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRV 19292
Query: 175 RVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTGDQDSILFI 233
+ R + + GE + + G+P P +W +G ++ + R + + D ++L +
Sbjct: 19293 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19352
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA---ALQWTPP 290
+ R D+G+Y LT++ ++ V++KPGPP+ L++ G A +L W P
Sbjct: 19353 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGP--LEINGLTAEKCSLSWGRP 19410
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
Q+ G ++ Y+V+K + W T+C ++ L+ GN Y FRV N G+
Sbjct: 19411 QEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGV 19468
Score = 112 bits (279), Expect = 1e-24
Identities = 72/284 (25%), Positives = 129/284 (45%), Gaps = 7/284 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ ++VT+ W+ P G + GY++E W+ S ++ T
Sbjct: 18107 DPPGRPEAIV---ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLET 18163
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L ++ RV A ++AG P+ I R+ I+AP + + +
Sbjct: 18164 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18223
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALD--SQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
GET L+ +GKP P W+ +G L+ + R+ +++ Q + L ++ R+D G+Y
Sbjct: 18224 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L + I + V+++PGPP +++ V L W PP G + Y+++
Sbjct: 18284 LKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE 18343
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
K + W V ++ L+ GN Y FRV + N G+
Sbjct: 18344 KRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18387
Score = 107 bits (267), Expect = 2e-23
Identities = 103/376 (27%), Positives = 164/376 (43%), Gaps = 17/376 (4%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T+P +E VP+ L++ D + +SV +SW P+ G + YV+E R+G E
Sbjct: 20957 TEPVKAAE-VPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE--RKGKGEQTWS 21013
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
A + V L RV A + G P + PI ++E I P++ +
Sbjct: 21014 HAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIP 21072
Query: 181 RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
++G V+L++P++GKPKP +W +G L +S+ V + L I++A++
Sbjct: 21073 GAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKE 21132
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSS----IRLLDVWGCNAALQWTPPQDTGN 295
G+Y TV +++ + + I VI GPPS IR ++ + L W P+D G
Sbjct: 21133 HGGKY--TVILDNAVCRIAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGG 21189
Query: 296 TELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
E+ Y ++K + W V TT + +L+ Y FRV +EN G+S +
Sbjct: 21190 GEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSS 21249
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+A Q K I S+ S T D G S V + I+W
Sbjct: 21250 IIVAKHQFRIPGPPGKPVIYNVTSDGMSLTW---DAPVYDGGSEVTGFHVEKKERNSILW 21306
Query: 416 MK-NKMEIQGNPKYRA 430
K N I G +YRA
Sbjct: 21307 QKVNTSPISGR-EYRA 21321
Score = 107 bits (266), Expect = 3e-23
Identities = 88/337 (26%), Positives = 145/337 (43%), Gaps = 14/337 (4%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P++P LT + + S++T+ W+ P G +QGY++E R ++ V+ R T
Sbjct: 8798 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 8857
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVG 189
V NL + RV AV+ G P+ L + I+++ P I++ +R I+ + G
Sbjct: 8858 LVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAG 8916
Query: 190 ETVNLQIPFQGKPKPQATWTHN-------GHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
E V++ G P P+ W+ N AL + + + + L I A R D G
Sbjct: 8917 EPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKG 8976
Query: 243 RYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYM 302
Y +T + + V ++P PP ++ + D+ + L W P D G +E+ Y+
Sbjct: 8977 TYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 9036
Query: 303 VQKAD--KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAH 360
+ K D +K +W V I LI Y FRV + N G+S K +
Sbjct: 9037 IDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQ 9096
Query: 361 --IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTP 395
+ KPK S S+T PL D+ +P
Sbjct: 9097 DPYRLPGPPGKPKVLARTKGSMLVSWTPPL-DNGGSP 9132
Score = 107 bits (266), Expect = 3e-23
Identities = 81/313 (25%), Positives = 135/313 (43%), Gaps = 22/313 (7%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P + +TA P P P P+ L + ++ ++V +SW+PP+ G + Y++E
Sbjct: 9498 PPVETIQRTTARDPIYP----PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC 9553
Query: 110 CREGAS-----EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
+ W + R + Q TV +L G ++ RV AV++AG P+ P
Sbjct: 9554 LAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCD 9613
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATW--------THNGHALD 216
+ P I L++ + G VN+ +G P P TW + L
Sbjct: 9614 CQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLY 9669
Query: 217 SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP-SSIRL 275
V+ D L I ++RSD+G Y +T A + + V+ +PGPP I+
Sbjct: 9670 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKF 9729
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
V L W PP+D G +++ Y+++K + W V T TI L+ G+
Sbjct: 9730 ESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHE 9789
Query: 336 YSFRVFSENLCGL 348
Y FR+ ++N G+
Sbjct: 9790 YVFRIMAQNKYGI 9802
Score = 105 bits (263), Expect = 7e-23
Identities = 89/333 (26%), Positives = 143/333 (42%), Gaps = 11/333 (3%)
Query: 23 KVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLD 80
KVP E +V E Q A AS A++P A D P P +
Sbjct: 22395 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRP---EVT 22451
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLE---LCREGASEWVPVSARPMMVTQQTVRNLAL 137
DV+ S+V++ W P G + GY++E + G W+ + + TV L+
Sbjct: 22452 DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE 22511
Query: 138 GDKFLLRVSAVSSAGA-GPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR-QVGETVNLQ 195
GD + RV A ++AG + P+ R+ PK + L + + G + L
Sbjct: 22512 GDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLD 22571
Query: 196 IPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLE 254
GKP+P+ WT LD ++VS++ + + I+ RSDSG+Y LTV+
Sbjct: 22572 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 22631
Query: 255 AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF 314
+ + V++ PGP + + V L W+ PQ+ G E+ Y+V++ + W
Sbjct: 22632 KAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWV 22691
Query: 315 TVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
V + ++ LI N Y FRV + N G
Sbjct: 22692 IVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG 22724
Score = 102 bits (254), Expect = 8e-22
Identities = 105/421 (24%), Positives = 177/421 (42%), Gaps = 43/421 (10%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P LT+ V+ T++W P+ G + Y++E WV V ++
Sbjct: 22642 DSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS 22701
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
R L ++++ RV AV+ G G P +PI R + P P + + +V
Sbjct: 22702 YVVTR-LIKNNEYIFRVRAVNKYGPGVPVE-SEPIVARNSFTIPS---PPGIPE----EV 22752
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQ--------RVSMRTGDQDSILFIRSAQRSD 240
G I KP+ + + +D + RV+ D+ L + S
Sbjct: 22753 GTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGC 22812
Query: 241 SGRYELTV-----RVEDLEAKAVIDILVIE-KPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
++ +T E EA I PGPPS+ R++D + +L WT P G
Sbjct: 22813 DYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDG 22872
Query: 295 NTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA 352
T+++GY+++ +K T QW+ V T T+ DL +G YSFRV + N+ G+S +
Sbjct: 22873 GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYS 22932
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
E+ +++ +I D A + + T G S +L SV P P
Sbjct: 22933 ESIAEIEPVERIEIP---------DLELADDLKKTV---TIRAGASLRLMVSVSGRPPPV 22980
Query: 413 IIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
I W K +++ RA+ + + L + K + +D+G YT +A N G+ S ++
Sbjct: 22981 ITWSKQGIDLAS----RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVK 23036
Query: 471 V 471
V
Sbjct: 23037 V 23037
Score = 100 bits (249), Expect = 3e-21
Identities = 105/423 (24%), Positives = 170/423 (40%), Gaps = 42/423 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DVSS TV W+PPE G +Q Y+LE C W SA ++
Sbjct: 11798 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSAT-VLTP 11856
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
TV L G++++ RV A + G GPP +P+ + + P P + T + +
Sbjct: 11857 GTTVTRLIEGNEYIFRVRAENKIGTGPPTE-SKPVIAKTKYDKPGRPDPPEV--TKVSKE 11913
Query: 189 GETVNLQIP------------FQGKPKPQATWTH-NGHALDSQRVSMRTGDQDSILFIRS 235
TV P + K K W N A+ +R+ ++ ++L
Sbjct: 11914 EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQ-----NLLPDHE 11968
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
Q E+ + L ++ V+ IE PGPP++ R++D + L W P G
Sbjct: 11969 YQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGG 12028
Query: 296 TELLGYMVQK----ADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++GY+V+ AD + + + T++ L Y FRV ++N G+
Sbjct: 12029 APIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGI 12088
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
A + + A KPK +E + + + L G +LF VR
Sbjct: 12089 GRPAELKE----------AIKPKEILEPPEIDLDASMRKLV--IVRAGCPIRLFAIVRGR 12136
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P PK+ W K ++ L + + L I + DSG Y+ +N GE +V
Sbjct: 12137 PAPKVTWRKVGIDNVVRKGQVDLVDT-MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12195
Query: 469 LEV 471
+ V
Sbjct: 12196 VRV 12198
Score = 100 bits (248), Expect = 4e-21
Identities = 80/321 (24%), Positives = 140/321 (43%), Gaps = 21/321 (6%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCR 111
P P+ ST D P P T+ DV +SV ++W PE G ++ YV+E+ +
Sbjct: 7468 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLK 7527
Query: 112 EGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEA 171
G EWV V A + TQ + L G ++ RV AV+ AG P+ P+ RE +
Sbjct: 7528 TGTDEWVRV-AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYP 7586
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKP------------QATWTHNGHALDSQR 219
P PR L I + + +P + P + W + +
Sbjct: 7587 PS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTK 7644
Query: 220 VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
++ + S+ R A + G+ + T +ED +V+ PGPP ++ ++DV
Sbjct: 7645 CTVTPLTEGSLYVFRVAAENAIGQSDYT-EIED----SVLAKDTFTTPGPPYALAVVDVT 7699
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSF 338
+ L+W PP++ G + Y+++K ++ +W + P ++D+I G F
Sbjct: 7700 KRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQF 7759
Query: 339 RVFSENLCGLSTSATVTKELA 359
+V +EN G+ + T+ L+
Sbjct: 7760 QVRAENEAGVGHPSEPTEILS 7780
Score = 97.1 bits (240), Expect = 3e-20
Identities = 80/302 (26%), Positives = 132/302 (43%), Gaps = 37/302 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P L D++ +VT++W P+ G + GY +E +WV + P+ T
Sbjct: 7384 DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDT 7443
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V+ L K+ RV A + AG G P+ +PI I++ I+ P + ++ V
Sbjct: 7444 TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-----GKPTVKDV 7498
Query: 189 GETVNLQIPFQGKPKPQATWT---HNGHA-LDSQRVSM-RTGDQDSILFIRSAQRS---- 239
G+T + WT H+G A ++S + M +TG + + +
Sbjct: 7499 GKT-----------SVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLL 7547
Query: 240 ----DSGRYELTVRV-----EDLEAKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQW 287
+ Y VR E ++ +L EK P PP + ++++ A L+W
Sbjct: 7548 PGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKW 7607
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
T P+ G + + Y+V+K D + W TV T CT++ L G+ Y FRV +EN G
Sbjct: 7608 TVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIG 7667
Query: 348 LS 349
S
Sbjct: 7668 QS 7669
Score = 96.7 bits (239), Expect = 4e-20
Identities = 97/445 (21%), Positives = 172/445 (38%), Gaps = 86/445 (19%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP+ V + D++ SVT+ WEPP+ G + Y+L + W VS
Sbjct: 20072 RPGPPTGPV-------VISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVS 20124
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A + T V L G+++ R+ A + G I ++I++
Sbjct: 20125 AT-VARTMMKVMKLTTGEEYQFRIKAENRFG------------ISDHIDSA--------- 20162
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHN-----------------GHALDSQRVSMRT 224
V +++P+ P W N G A+ + M+
Sbjct: 20163 ---------CVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMK- 20212
Query: 225 GDQDSILFIRSAQR------------SDSGRYELTVRVEDLEAKAVID-----ILVIEKP 267
D++SIL+ ++ + S YE V E+ +L I+
Sbjct: 20213 -DRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC 20271
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCT 326
PP ++R+ D+ + +L W P G +++ GY+V++ D G+W T
Sbjct: 20272 EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFI 20331
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
IS L + Y FRVF+ N G + + ++ + I D P + +++E +
Sbjct: 20332 ISGLTQNSQYEFRVFARNAVG--SISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRA 20389
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
G S +L + P P I W K+ E+Q N + + ++ I+
Sbjct: 20390 ---------GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADR 20440
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
+SG Y K N +G AS R+++
Sbjct: 20441 LNSGCYELKLRNAMGSASATIRVQI 20465
Score = 96.3 bits (238), Expect = 5e-20
Identities = 95/412 (23%), Positives = 163/412 (39%), Gaps = 42/412 (10%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D+P P + D+VSS VT SW+PPE G + + YV+E+ + ++ WV ++ +
Sbjct: 14660 DIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRT 14719
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPA-----MLDQPIHIRENIEAPKIRVPRHLRQ 182
T + R L G ++ RV A + G GP + + P + P++
Sbjct: 14720 TYKATR-LTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQV-------- 14770
Query: 183 TYIRQVGETVNLQIPFQGKPKPQATW-----THNGHALDSQRVSMRTGDQDSILFIRSAQ 237
T + + T++ P P + NG + ++ G+ +S+
Sbjct: 14771 TAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGN-----IFKSSG 14825
Query: 238 RSDSGRYELTVRVEDLEAKAVID-----ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+D YE V E++ K+ +L ++ PP L++ L+W P+
Sbjct: 14826 LTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEY 14885
Query: 293 TGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
TG ++ Y+V+K D G+W T+S L +Y FRV ++N G +
Sbjct: 14886 TGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISP 14945
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ + I D PK ++ F + G + +L V P P
Sbjct: 14946 PSEPSDA--ITCRDDVEAPKIKVDVKFKDTVILKA---------GEAFRLEADVSGRPPP 14994
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ W K+ E++G K L + + DSG YT A N G A
Sbjct: 14995 TMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFA 15046
Score = 94.4 bits (233), Expect = 2e-19
Identities = 96/427 (22%), Positives = 163/427 (38%), Gaps = 50/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ V +D+V++ S+T+SW PP+ G + Y++E + W VS
Sbjct: 15743 KPGPPTGPVK-------MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVS 15795
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGP-----PAMLDQPIHIRENIEAPKIRV 176
A T + R L G ++ R++A + G P + P + P + +
Sbjct: 15796 ATVARTTIKACR-LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTL 15854
Query: 177 PRHLRQTYIRQVGETVN------LQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
R + Q E ++ + + K + W Q TG ++ +
Sbjct: 15855 SS--RDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 15912
Query: 231 LFIRSAQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAAL 285
YE V E++ + V + V P PP + V + L
Sbjct: 15913 ------------EYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTL 15960
Query: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSEN 344
QW P G +++ GY+V+K + G+W T ++ L+ + Y FRV + N
Sbjct: 15961 QWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARN 16020
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G+ + + + I D P+ S P + + H G S ++
Sbjct: 16021 AAGVFSEPS--ESTGAITARDEVDPPR------ISMDPKYKDTIVVHA---GESFKVDAD 16069
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ P P I W+K E+ + S +L ++ DSG Y KA NV GE S
Sbjct: 16070 IYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERS 16129
Query: 465 VDCRLEV 471
V ++V
Sbjct: 16130 VTVNVKV 16136
Score = 90.5 bits (223), Expect = 3e-18
Identities = 95/411 (23%), Positives = 162/411 (39%), Gaps = 38/411 (9%)
Query: 69 DVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
DVP P + + DV+ +T+SW+PP+ G + Y++E W VS+
Sbjct: 11105 DVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK- 11163
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T+ + +L G +++ RV A + G GPP LD + ++ +P P T I +
Sbjct: 11164 TKLKIPHLQKGCEYVFRVRAENKIGVGPP--LDSTPTVAKHKFSPP-SPPGKPVVTDITE 11220
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
TV+ +P P + + + V + + F R + YE
Sbjct: 11221 NAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKF-RVTGLYEGNTYEFR 11279
Query: 248 VRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
V E+L + + I+ PGPP + +L D A L WT P G + +L
Sbjct: 11280 VFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPIL 11339
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCT--ISDLIIGNSYSFRVFSENLCGLS-----TSA 352
GY+V+ T QW + + C + LI GN Y FR+ + N+ G +
Sbjct: 11340 GYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAES 11399
Query: 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
+ K++ H + ++ + I T G + ++ V+ P+P
Sbjct: 11400 VIAKDILHPPEVELDVTCRDVI-----------------TVRVGQTIRILARVKGRPEPD 11442
Query: 413 IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
I W K + + + + L+I++ D G Y A N G A
Sbjct: 11443 ITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 11493
Score = 87.4 bits (215), Expect = 3e-17
Identities = 96/411 (23%), Positives = 161/411 (39%), Gaps = 48/411 (11%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
+++ +T+ W+ P G + Y++E W + + T L G++
Sbjct: 21566 NITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDK-CEAQSYTAIKLINGNE 21624
Query: 141 FLLRVSAVSSAGAGPPAMLDQPI-HIRENI-EAPKIRVPRHLRQTYIRQV-------GET 191
+ RVSAV+ G G P D + I+ + +AP I P ++ I G +
Sbjct: 21625 YQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGS 21684
Query: 192 VNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVE 251
Q + + K W + S+R T + + L ++ YE V E
Sbjct: 21685 EIQQYILERREKKSTRWVK----VISKRPISETRFKVTGL-------TEGNEYEFHVMAE 21733
Query: 252 DLEA---KAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
+ + I L+ + PGPP+ +++ D +L+W+ P G E++GY++
Sbjct: 21734 NAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYII 21793
Query: 304 QKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ 362
+ G W V E T T++DL G Y FRV + N G S VT I+
Sbjct: 21794 EMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIK 21850
Query: 363 KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI 422
D P+ I+ +F + H G S +LF + + P P +W K
Sbjct: 21851 AVDRLTAPELDIDANFKQT---------HVVRAGASIRLFIAYQGRPTPTAVWSKP---- 21897
Query: 423 QGNPKYRA--LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
N RA + TL + + D+G YT N G S+ ++V
Sbjct: 21898 DSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 21948
Score = 86.7 bits (213), Expect = 4e-17
Identities = 51/180 (28%), Positives = 95/180 (52%), Gaps = 4/180 (2%)
Query: 180 LRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQR 238
L++ Y VG T+ L + + G+P P TW H L +S+ +++ + + L +++ QR
Sbjct: 24137 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 24196
Query: 239 -SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA-LQWTPPQDTGNT 296
+ +G+Y++ + A++D+ + +KP P+ +++ N+A + W PP D G +
Sbjct: 24197 KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGS 24256
Query: 297 ELLGYMVQKADKKTG-QWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+ Y+V+K + K G +W V TTC I +L Y FRV ++N G+S V+
Sbjct: 24257 WITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVS 24316
Score = 86.3 bits (212), Expect = 6e-17
Identities = 51/201 (25%), Positives = 95/201 (47%), Gaps = 6/201 (2%)
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
APKI+ Q + VG+ + + +P+ PK +A W L ++ + T +Q S
Sbjct: 6502 APKIKTAD---QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSF 6557
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPP 290
+ A++ D GRY++ ++ + +A+ I++ VI+ PGP ++ + + + +L W P
Sbjct: 6558 RILE-AKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEP 6616
Query: 291 QDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGN-SYSFRVFSENLCGLS 349
G ++++GY+V++ D K W +R T++ L G Y FRV + N G
Sbjct: 6617 LTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTG 6676
Query: 350 TSATVTKELAHIQKADIAAKP 370
+ K D+ P
Sbjct: 6677 EPVETDNPVEARSKYDVPGPP 6697
Score = 86.3 bits (212), Expect = 6e-17
Identities = 96/417 (23%), Positives = 171/417 (41%), Gaps = 60/417 (14%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P+ P+ D+V++ ++T+ W PP+ G + Y+LE ++WV ++ T
Sbjct: 13581 IPTGPI--KFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTF 13638
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
+ R L G ++ RVSA + G G + +PI R + P P ++ V
Sbjct: 13639 RVTR-LHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVS 13696
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR-YELTV 248
T PK G+ L+ + +++S+L+ R+ + R +++T
Sbjct: 13697 LTWT-------DPKKTGGSPITGYHLEFK-------ERNSLLWKRANKTPIRMRDFKVTG 13742
Query: 249 RVEDLEAK---AVIDILVIEKPG-------------PPSSIRLLDVWGCNAALQWTPPQD 292
E LE + I++ + KP PP ++++ + L WT P+
Sbjct: 13743 LTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKY 13802
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTS 351
G +L GY+V+K D + W P T++DL+ G Y FR+ ++N G ++
Sbjct: 13803 DGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISA 13862
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQL-------FCS 404
+ + E I +D EAP+ + D T G + + S
Sbjct: 13863 PSESTET--------------IICKDEYEAPTI---VLDPTIKDGLTIKAGDTIVLNAIS 13905
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P PK W K +I+ + + S L I+ + D+G YT A N G
Sbjct: 13906 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 85.9 bits (211), Expect = 7e-17
Identities = 105/431 (24%), Positives = 166/431 (38%), Gaps = 52/431 (12%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T KP PP V DDVS+ S+T+SW PP G + Y+++ + W
Sbjct: 16822 TLDKPDPPKGPVK-------FDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWD 16874
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
VSA T + V L G ++ R+ A + G A+ PI + + P P
Sbjct: 16875 VVSATVARTTLK-VTKLKTGTEYQFRIFAENRYGQSF-ALESDPIVAQYPYKEPG--PPG 16930
Query: 179 HLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIR---- 234
T I + + P P G+ L+ + +++SIL+ +
Sbjct: 16931 TPFATAISKDSMVIQWHEPVNNGGSPVI-----GYHLERK-------ERNSILWTKVNKT 16978
Query: 235 -------SAQRSDSG-RYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGC 281
AQ + G YE V E++ +A + V P PP + + V
Sbjct: 16979 IIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRN 17038
Query: 282 NAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRV 340
LQWT P G + + GY+V+K D G+W T T+S L Y FRV
Sbjct: 17039 EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRV 17098
Query: 341 FSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
++N G + + + I AK + + R S P F + + G + +
Sbjct: 17099 IAKNAAGAISKPSDS-------TGPITAKDEVELPR-ISMDPKFRDTIVVNA---GETFR 17147
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L V P P I W++ EI+ + + + L ++ D G Y +A NV
Sbjct: 17148 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA 17207
Query: 461 GEASVDCRLEV 471
G S ++V
Sbjct: 17208 GSKSFPVNVKV 17218
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/199 (29%), Positives = 95/199 (47%), Gaps = 11/199 (5%)
Query: 169 IEAP-KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTHNGHALDSQR--VSMR 223
+E P KI +P+ L GE V+++IPF GKP P TW +D+ +
Sbjct: 24522 VEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIV 24581
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T S++F +R D+G Y + + + +++ V + P PP +++ DV +
Sbjct: 24582 TRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSV 24641
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSE 343
L WT P G +++ Y+V+K +W V + T T+ +L SY FRV +E
Sbjct: 24642 NLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAE 24700
Query: 344 NLCGLS-----TSATVTKE 357
N GLS + T+TKE
Sbjct: 24701 NKFGLSKPSEPSEPTITKE 24719
Score = 85.1 bits (209), Expect = 1e-16
Identities = 98/427 (22%), Positives = 161/427 (37%), Gaps = 48/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + D+V+ + +SW+PP G + Y++E G W+PV+
Sbjct: 10414 RPGPPVGPV-------SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVT 10466
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + V L G ++ R+ A + G P + D + ++ P P
Sbjct: 10467 SASAKTTCK-VSKLLEGKDYIFRIHAENLYGISDPLVSDS-MKAKDRFRVPD--APDQPI 10522
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ-DSILFIRSAQRSD 240
T + + V P G KP + S+R + T D R +
Sbjct: 10523 VTEVTKDSALVTWNKPHDGG-KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLE 10581
Query: 241 SGRYELTVRVEDL--------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
+YE V E+ +K V I KP PP + +D + L W PP+
Sbjct: 10582 GCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRH 10641
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT-----ISDLIIGNSYSFRVFSENLCG 347
G +++LGY+V+ +W + P +C ++ L G +Y FRV + N G
Sbjct: 10642 DGGSKILGYIVEYQKVGDEEWRRA--NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAG 10699
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCS 404
S A V P+ + +D E P + G + +L
Sbjct: 10700 ESDPAHV---------------PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAI 10744
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
++ P PK+ W K + K R LEIR + D G+Y+ N G +
Sbjct: 10745 IKGVPFPKVTWKKEDRDAP--TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKT 10802
Query: 465 VDCRLEV 471
V ++ V
Sbjct: 10803 VSVKVLV 10809
Score = 84.7 bits (208), Expect = 2e-16
Identities = 101/423 (23%), Positives = 164/423 (38%), Gaps = 52/423 (12%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP L + + V+++WE P G + GYV+E WV + R
Sbjct: 6591 DVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC- 6649
Query: 129 QQTVRNLALGD-KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ TV L G ++L RVSA + G G P D P+ R + P P ++ T + +
Sbjct: 6650 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP--GPPLNVTITDVNR 6707
Query: 188 VGETVNLQIP------------FQGKPKPQATW----THNGHALDSQRVSMRTGDQDSIL 231
G ++ + P + + K W T L + + G + S
Sbjct: 6708 FGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFR 6767
Query: 232 FIRSAQRSDSGRYELT---VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
+R+ R G+ V+V D IE+P PP ++ D + L+W
Sbjct: 6768 -VRAQNRIGVGKPSAATPFVKVAD----------PIERPSPPVNLTSSDQTQSSVQLKWE 6816
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-TTCTISDLIIGNSYSFRVFSENLCG 347
PP G + +LGY++++ ++ W + P T ++ L GN Y +RV +EN G
Sbjct: 6817 PPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAG 6876
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+S + + L AD A F+E + +F L P T L S
Sbjct: 6877 VSDPSEILGPLT----ADDA-----FVEPTM-DLSAFKDGL--EVIVPNPITILVPST-G 6923
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN----VLGEA 463
P+P W ++ + + + L I D G+YT K N + GE
Sbjct: 6924 YPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEI 6983
Query: 464 SVD 466
V+
Sbjct: 6984 DVN 6986
Score = 83.6 bits (205), Expect = 4e-16
Identities = 97/430 (22%), Positives = 166/430 (38%), Gaps = 69/430 (16%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP V + V++ T++W+PP + G + Y++E W V
Sbjct: 16139 RPGPPEGPV-------VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVD 16191
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A ++ + V L G+++ R+ AV+ G G P + +P+ + P P+
Sbjct: 16192 ANVQTLSCK-VTKLLEGNEYTFRIMAVNKYGVGEP-LESEPVVAKNPFVVPD--APKAPE 16247
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQR--- 238
T + T + I +P G+ L+ + D++ I + R +R
Sbjct: 16248 VTTV-----TKDSMIVVWERPASDGGSEILGYVLEKR-------DKEGIRWTRCHKRLIG 16295
Query: 239 ---------SDSGRYELTVRVEDLEA----------KAVIDILVIEKPGPPSSIRLLDVW 279
++ YE V E+ + D I KPGPP++ +++D+
Sbjct: 16296 ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD--PIYKPGPPNNPKVIDIT 16353
Query: 280 GCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW--FTVLERYHPTTCTISDLIIGNSYS 337
+ L W+ P G E+ GY+V+K D G+W T + T + L+ + Y+
Sbjct: 16354 RSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYN 16413
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADH---TST 394
FR+ + N G+ A V P I + EAP L
Sbjct: 16414 FRICAINKAGVGEHADV---------------PGPIIVEEKLEAPDIDLDLELRKIINIR 16458
Query: 395 PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
G S +LF ++ P P++ W K EI+ S +L + + +DSG YT
Sbjct: 16459 AGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTL 16516
Query: 455 KAINVLGEAS 464
N G S
Sbjct: 16517 TLENSSGTKS 16526
Score = 82.8 bits (203), Expect = 6e-16
Identities = 88/406 (21%), Positives = 157/406 (38%), Gaps = 29/406 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + +VS+ T++W PP G ++ Y+LE W VS +
Sbjct: 13974 DVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVS-EDIQSC 14032
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+ L G++++ RVSAV+ G G P +P+ + + P P + + +
Sbjct: 14033 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-SEPVKMVDRFGPPG--PPEKPEVSNVTKN 14089
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
TV+ + P + S R S L + + YE V
Sbjct: 14090 TATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRV 14149
Query: 249 RVEDLE-----AKAVIDILVIEK---PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+ ++A +L+ + PGPPS+ + D +A+L W P G E+ G
Sbjct: 14150 SAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITG 14209
Query: 301 YMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKEL 358
Y+V+ W T T + DL Y+FR+ + N G+ A +
Sbjct: 14210 YVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD-- 14267
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
I + ++A DF + L G S ++F ++ P P++ W K+
Sbjct: 14268 VEIVEREMAP--------DFELDAELRRTLVVRA---GLSIRIFVPIKGRPAPEVTWTKD 14316
Query: 419 KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
+ ++ + + L I + + +D+G + N G+ S
Sbjct: 14317 NINLKNRANIE--NTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 14360
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/411 (21%), Positives = 155/411 (37%), Gaps = 40/411 (9%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + ++ + S +SWEPP G + Y+++ W VSA + +T
Sbjct: 12890 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSAT-VPIT 12948
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
+V L G ++ R+ A + G G P + +P + + P P + I +
Sbjct: 12949 SCSVEKLIEGHEYQFRICAENKYGVGDP-VFTEPAIAKNPYDPPGRCDPPVISN--ITKD 13005
Query: 189 GETVNLQIPFQGKPKP------------QATWTHNGHALDSQRVSMRTGDQDSILF---I 233
TV+ + P P WT +R TG Q+ + +
Sbjct: 13006 HMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRV 13065
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
+ ++ G+ +KA PGPP+ ++ D + +L W P
Sbjct: 13066 TAINKAGPGK-------PSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYD 13118
Query: 294 GNTELLGYMVQKADKKTGQWF--TVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
G + ++GY+V+ + W + + T ++ L+ Y FRV++ N G S
Sbjct: 13119 GGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13178
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+ V + H K DI P+G ++ D + G + +L+ V+ P P
Sbjct: 13179 SDVPDK--HYPK-DILIPPEGELDADLRKTLILRA---------GVTMRLYVPVKGRPPP 13226
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
KI W K + ++ S L + +D+G Y N G+
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 13277
Score = 81.6 bits (200), Expect = 1e-15
Identities = 99/427 (23%), Positives = 165/427 (38%), Gaps = 49/427 (11%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP V D+VS+ V +SWEPP G + Y++E + W VS
Sbjct: 17907 KPGPPVGPV-------RFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS 17959
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
A T + + L G ++ R+ A + G P LD I ++ P + P
Sbjct: 17960 ATVARTTIK-ITKLKTGTEYQFRIFAENRYGKSAP--LDSKAVI---VQYP-FKEPGPPG 18012
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSM------RTGDQDSILFIRS 235
++ + + L + + T H ++ S+ +T QD+ ++
Sbjct: 18013 TPFVTSISKDQML-VQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF--KT 18069
Query: 236 AQRSDSGRYELTVRVEDL----EAKAVIDILVIEKP-GPPSSIRLLDVWGCNAALQWTPP 290
+ YE V E++ + V + V P PP + + N L+W P
Sbjct: 18070 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18129
Query: 291 QDTGNTELLGYMVQKADKKTGQWF-----TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
G +++ GY+V+K D G+W VLE T T+S L+ Y FRV + N
Sbjct: 18130 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLE----TEFTVSGLVEDQRYEFRVIARNA 18185
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
G + + + I D P ++ P + + H G + L +
Sbjct: 18186 AGNFSEPSDSS--GAITARDEIDAPNASLD------PKYKDVIVVHA---GETFVLEADI 18234
Query: 406 RASPKPKIIWMKNKMEIQGN-PKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
R P P ++W K+ E++ + S TL ++ D G Y K NV G S
Sbjct: 18235 RGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18294
Query: 465 VDCRLEV 471
+ ++V
Sbjct: 18295 IPITVKV 18301
Score = 81.6 bits (200), Expect = 1e-15
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 17/229 (7%)
Query: 251 EDLEAKAVIDILV-IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ LE +V+ I EKPG P + V + + W PP G ++ Y ++K +KK
Sbjct: 24311 DPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKK 24370
Query: 310 TGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAA 368
+W +V E T ++ +LI G Y FRV ENL G S + +++ + K+D+
Sbjct: 24371 QNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT--PKSDVPI 24428
Query: 369 KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNP-K 427
+AP F + L + + L C V PKP + W + EI + K
Sbjct: 24429 -----------QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLK 24477
Query: 428 YRALS-EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
YR + G L I + D+ VY +A N G S LEV+ A
Sbjct: 24478 YRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPA 24526
Score = 80.1 bits (196), Expect = 4e-15
Identities = 103/486 (21%), Positives = 178/486 (36%), Gaps = 60/486 (12%)
Query: 4 KNTSEGPACSPEETASESAKVPTAEPPG--EVAVSESTREEQVPKPQAPAPQAPTASTAT 61
K T+ S + S S K + E G E+ VS S VP T
Sbjct: 18939 KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPI---------TIIVLD 18989
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
+P PP + +D+VS S+T+SW PPE G + Y++E ++ W VS
Sbjct: 18990 RPGPPGP--------IRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVS 19041
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAV-----SSAGAGPPAMLDQPIHIRENIEAPKIRV 176
+ + VR L G ++ RV A SS + + P PK+
Sbjct: 19042 QAVARTSIKIVR-LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV-- 19098
Query: 177 PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSA 236
+ + V Q+P G+ L+ + S + + + I
Sbjct: 19099 ------VHATKSTMLVTWQVPVNDGGSRVI-----GYHLEYKERSSILWSKANKILIADT 19147
Query: 237 QRSDSG-----RYELTVRVEDLE-----AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
Q SG YE V E++ +K+ + + PP + ++ + +L+
Sbjct: 19148 QMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLK 19207
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENL 345
W+ P G ++ GY+V++ + G+W T +++L Y FRVF+ N
Sbjct: 19208 WSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNA 19267
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
+ + ++ I D P+ ++ F + G ++ +
Sbjct: 19268 A--DSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVI---------VVKAGEVLKINADI 19316
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
P P I W K+ +EI+ + +S L ++ D+G Y NV G SV
Sbjct: 19317 AGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSV 19376
Query: 466 DCRLEV 471
+V
Sbjct: 19377 AVNCKV 19382
Score = 79.7 bits (195), Expect = 5e-15
Identities = 57/211 (27%), Positives = 89/211 (42%), Gaps = 16/211 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + E+P PP I L+DV + +L W P+ G + +LGY+V+ K + +
Sbjct: 15538 LPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDK 15597
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T T TI+ LI G YSFRV ++N G+S ++ +
Sbjct: 15598 WAT-CATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV-------------- 15642
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
I +D P+F T G ++ P P + W K+ + ++ + A S
Sbjct: 15643 -IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAES 15701
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ L I+ D G Y K N GEA
Sbjct: 15702 TENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732
Score = 79.0 bits (193), Expect = 9e-15
Identities = 54/205 (26%), Positives = 93/205 (45%), Gaps = 12/205 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P PP +++ D + L W PP++ G + + GY+V++ + + +W E T
Sbjct: 7091 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7150
Query: 327 ISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQ 386
++ L G Y++RV + N G S + T+E IQ D P+ F++ +
Sbjct: 7151 VTGLEEGKWYAYRVKALNRQGASKPSRPTEE---IQAVDTQEAPEIFLD---------VK 7198
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
LA T G +L +V P+PKI W K M ++ + + + T+ I
Sbjct: 7199 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 7258
Query: 447 FDSGVYTCKAINVLGEASVDCRLEV 471
D+G Y +A+NV G A+ + V
Sbjct: 7259 SDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 78.6 bits (192), Expect = 1e-14
Identities = 87/447 (19%), Positives = 169/447 (37%), Gaps = 72/447 (16%)
Query: 61 TKPAPPSEDV--------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
++P+ PS+ V PS P L + +++ ++ + W PE+ G + Y++E
Sbjct: 7569 SEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDV 7628
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
W V + T+ TV L G ++ RV+A ++ G ++ + ++ P
Sbjct: 7629 RRKGWQTVDTT-VKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP 7687
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF 232
Y V + + + +P N QR + ++ +
Sbjct: 7688 G--------PPYALAVVDVTKRHVDLKWEPPK------NDGGRPIQRYVIEKKERLGTRW 7733
Query: 233 IRSAQRSDSG-RYELTVRVEDLEAKAVI---------------DILVIEKP----GPPSS 272
+++ + + + +T +E E + + +IL IE P PP
Sbjct: 7734 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLD 7793
Query: 273 IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDL-- 330
+ + D + A+ W PP+ G + ++GY V+ T +W V R I DL
Sbjct: 7794 LHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSR------PIKDLKF 7847
Query: 331 ------IIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ Y RV + N G+S + +++ + + +D P+
Sbjct: 7848 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 7892
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
D G + RA P P + W K+ E++ + + ++ LE+ K
Sbjct: 7893 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 7952
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
D+G+YT N LG A+ ++V
Sbjct: 7953 VRADAGIYTITLENKLGSATASINVKV 7979
Score = 77.0 bits (188), Expect = 3e-14
Identities = 92/421 (21%), Positives = 155/421 (36%), Gaps = 53/421 (12%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP + V++ +T+ W PP G + Y++E W VS
Sbjct: 20468 KPGPPGGPIE-------FKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVS 20520
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ T + G++++ RV AV+ G G P D + + +P
Sbjct: 20521 EH-LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPE--- 20576
Query: 182 QTYIRQVGETVNLQIPF------------QGKPKPQATWTH--NGHALDS-QRVSMRTGD 226
T I + TV P + + K W D+ Q+V+ T +
Sbjct: 20577 VTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTEN 20636
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
D + + + G + E E D I+ PGPP+ IR+ D + L
Sbjct: 20637 SDYQYRVCAVNAAGQGPFS-----EPSEFYKAAD--PIDPPGPPAKIRIADSTKSSITLG 20689
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSEN 344
W+ P G + + GY+V+ + +W TV + T +S+L G +Y FRV + N
Sbjct: 20690 WSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVN 20749
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTST---PGYSTQL 401
G + + + +D EAP +A TS G Q+
Sbjct: 20750 CAGQGEPIEMNEPVQ---------------AKDILEAPEIDLDVALRTSVIAKAGEDVQV 20794
Query: 402 FCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ P P + W K++ + + +Y + L I + + D+G Y N +G
Sbjct: 20795 LIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854
Query: 462 E 462
E
Sbjct: 20855 E 20855
Score = 75.9 bits (185), Expect = 8e-14
Identities = 60/238 (25%), Positives = 98/238 (41%), Gaps = 24/238 (10%)
Query: 227 QDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
+ +I + R ++ G + V VE ++A + E P PP + L DV +A+L
Sbjct: 17684 EGAIYYFRVMAENEFG---VGVPVETVDA-----VKAAEPPSPPGKVTLTDVSQTSASLM 17735
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLC 346
W P+ G + +LGY+V+ K T +W V E ++ L G Y FRV + N
Sbjct: 17736 WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQEYQFRVKAYNEK 17794
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
G K+D I +D + PS P ++ G ++ V
Sbjct: 17795 G---------------KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVI 17839
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P+P I W+K+ ++ + L I++ + D G YT A N G A+
Sbjct: 17840 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTAT 17897
Score = 74.7 bits (182), Expect = 2e-13
Identities = 95/428 (22%), Positives = 168/428 (39%), Gaps = 54/428 (12%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PPS+ P P+ D++ + SV +SW+ PE G + Y +E + W V +
Sbjct: 21159 PPSK--PKGPI--RFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21214
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTY 184
T + V NL ++ RV A + G + QP+ + + R+P
Sbjct: 21215 ARTTFK-VPNLVKDAEYQFRVRAENRYG------VSQPLVSSIIVAKHQFRIPG------ 21261
Query: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR- 243
G+ V + G ++G + + + +++SIL+ + SGR
Sbjct: 21262 --PPGKPVIYNVTSDGMSLTWDAPVYDGGS-EVTGFHVEKKERNSILWQKVNTSPISGRE 21318
Query: 244 YELTVRVEDLE-------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
Y T VE L+ +K + + ++ PG P I DV
Sbjct: 21319 YRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETIT 21375
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN 344
L+W PP G ++++GY ++K T++ L G+ Y FR+ + N
Sbjct: 21376 LKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARN 21435
Query: 345 LCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
G T + ++ I D P +E P + L + G S ++
Sbjct: 21436 AVG--TISPPSQSSGIIMTRDENVPP--IVEF----GPEYFDGLIIKS---GESLRIKAL 21484
Query: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V+ P P++ W K+ +EI+ G +L +R + GVYT +A N G A
Sbjct: 21485 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21544
Query: 465 VDCRLEVK 472
+ +++V+
Sbjct: 21545 AEIKVKVQ 21552
Score = 72.8 bits (177), Expect = 6e-13
Identities = 91/421 (21%), Positives = 155/421 (36%), Gaps = 39/421 (9%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ L ++ +++ ++SW P+ G + Y++E W +
Sbjct: 19385 KPGPPAGP-------LEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT-IC 19436
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLR 181
+ +T V L G++++ RV+ V+ G G P + I + P P L
Sbjct: 19437 EGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP-LESVAIKALDPFTVPS--PPTSLE 19493
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDS 241
T + + T+ P + + +S R L ++S +
Sbjct: 19494 ITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREG 19553
Query: 242 GRYELTVRVED---LEAKAVIDILV-----IEKPGPPSSIRLLDVWGCNAALQWTPPQDT 293
YE V E+ L + L+ + P PPS +++D + W P
Sbjct: 19554 CEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFD 19613
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSAT 353
G + GY V+ W T ++ T TIS L G Y FRV S N G S +
Sbjct: 19614 GGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSD 19673
Query: 354 VTKELAHIQKADIAAKPKGFIERDFSEAPSF---TQPLADHTSTPGYSTQLFCSVRASPK 410
++ P+ I ++ E P F ++ G S + R P
Sbjct: 19674 -------------SSDPQ--IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 19718
Query: 411 PKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
P ++W K +++ + T+E + DSG YT NVL AS+ ++
Sbjct: 19719 PNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRN--DSGKYTLTIQNVLSAASLTLVVK 19776
Query: 471 V 471
V
Sbjct: 19777 V 19777
Score = 72.4 bits (176), Expect = 8e-13
Identities = 49/217 (22%), Positives = 89/217 (41%), Gaps = 16/217 (7%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ I V E P PP I + DV + +L WT P+ G ++++ Y+V+ K + +
Sbjct: 16620 LPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEK 16679
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W + R I++L G Y FRV + N G S ++ +
Sbjct: 16680 W-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI-------------- 16724
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+ +D P + ++ G ++ + PKP I W K+ + ++ +
Sbjct: 16725 -VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTD 16783
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRL 469
+ TL I++ D G Y NV+G+ + +
Sbjct: 16784 SLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 16820
Score = 71.2 bits (173), Expect = 2e-12
Identities = 68/289 (23%), Positives = 112/289 (38%), Gaps = 12/289 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P + DV++ S ++W PP G + YV+E + W +S+ + T
Sbjct: 7285 DKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSS-TVKDT 7343
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
L +++ RV+A + G G P PI + + P P L + I +
Sbjct: 7344 NFKATKLIPNKEYIFRVAAENMYGVGEPVQA-SPITAKYQFDPP--GPPTRLEPSDITKD 7400
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
T+ P P + D+ + R ++ +Y V
Sbjct: 7401 AVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRV 7460
Query: 249 RVEDL-----EAKAVIDILV---IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG 300
E+L +K+ IL+ I+ P PP + DV + L WT P+ G ++
Sbjct: 7461 LAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIES 7520
Query: 301 YMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Y+++ T +W V E T + L+ G YSFRV + N G S
Sbjct: 7521 YVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 7569
Score = 69.3 bits (168), Expect = 7e-12
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 20/215 (9%)
Query: 253 LEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQ 312
L A+ + V E P PP + L+DV A ++W P+ G +++ GY+V+ K + +
Sbjct: 18785 LPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEK 18844
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
W T + TIS L G Y FRV + N G ++D
Sbjct: 18845 WSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKG---------------RSDPRQLGVP 18888
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV--RASPKPKIIWMKNKMEIQGNPKYRA 430
I RD PS P HT QL V + P+ + W K+ ++ +
Sbjct: 18889 VIARDIEIKPSVELPF--HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNV 18946
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465
S + V +L I++ S D G Y N G +V
Sbjct: 18947 SSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 18981
Score = 68.2 bits (165), Expect = 2e-11
Identities = 97/427 (22%), Positives = 157/427 (36%), Gaps = 57/427 (13%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSARPMM 126
D P P+ +D+ +SV WEPP G + Y LE + SEW+ V++ +
Sbjct: 8303 DTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTS-TLR 8361
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR 186
+ +V L G ++L RV A + G GPP + +P+ ++ P + +
Sbjct: 8362 HCKYSVTKLIEGKEYLFRVRAENRFGPGPPC-VSKPLVAKDPFGPPDAP-----DKPIVE 8415
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG---- 242
V T N + +PK + G+ L+ + V+ + + + + + + G
Sbjct: 8416 DV--TSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEG 8472
Query: 243 -RYELTVRVEDL----------EAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
Y V E+ + K D I PGPP R+ D L+W PP
Sbjct: 8473 LTYVFRVCAENAAGPGKFSPPSDPKTAHD--PISPPGPPIP-RVTDTSSTTIELEWEPPA 8529
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGL-- 348
G E++GY V K T +W E+ T+ ++ G Y RV + N G
Sbjct: 8530 FNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGP 8589
Query: 349 --STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVR 406
T E ++ KG I+ G + ++ V
Sbjct: 8590 PGETQPVTVAEPQEPPAVELDVSVKGGIQ-----------------IMAGKTLRIPAVVT 8632
Query: 407 ASPKPKIIWMKNKMEIQGNPKYRALSEQ--GVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P +W K + E+ K R + + L I+ D G Y A N G
Sbjct: 8633 GRPVPTKVWTKEEGELD---KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKF 8689
Query: 465 VDCRLEV 471
R+EV
Sbjct: 8690 AAARVEV 8696
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/235 (22%), Positives = 94/235 (40%), Gaps = 30/235 (12%)
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
F R ++ G E T E ++A E P PP S+ ++D+ +L W P+
Sbjct: 14441 FFRVMAENEYGIGEPTETTEPVKAS--------EAPSPPDSLNIMDITKSTVSLAWPKPK 14492
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS-- 349
G +++ GY+++ K + QW T + C + +L G Y+F+V + N G S
Sbjct: 14493 HDGGSKITGYVIEAQRKGSDQW-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP 14551
Query: 350 --TSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRA 407
+ + KE + + D+ + + + G + ++ V
Sbjct: 14552 RESRPVIVKEQTMLPELDLRGIYQKLV-----------------IAKAGDNIKVEIPVLG 14594
Query: 408 SPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
PKP + W K ++ + + L I + DSG Y A N++GE
Sbjct: 14595 RPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE 14649
Score = 66.6 bits (161), Expect = 5e-11
Identities = 85/431 (19%), Positives = 158/431 (36%), Gaps = 63/431 (14%)
Query: 69 DVPSAPLL-LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
D P P + D+ + + ++SW P G + Y++E C +WV A +
Sbjct: 12493 DAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS-VTK 12551
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
T V L G +++ RV A + G + +P+ + + VP + + +
Sbjct: 12552 TSCRVGKLIPGQEYIFRVRAENRFG------ISEPLTSPKMVAQFPFGVPSEPKNARVTK 12605
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRS-DSGRYEL 246
V N F +P + G + + + +++S+L++++ S Y
Sbjct: 12606 V----NKDCIFVAWDRPDSD---GGSPIIGYLIERK--ERNSLLWVKANDTLVRSTEYPC 12656
Query: 247 TVRVEDLEAKAVIDILVIEKPG------------------PPSSIRLLDVWGCNAALQWT 288
VE LE I + K G PP ++DV +L W
Sbjct: 12657 AGLVEGLEYS--FRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWA 12714
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWF---TVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
P+ G ++++GY V+ +W T + T + L Y FR +
Sbjct: 12715 RPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTA 12774
Query: 346 CGLSTSATVTKELAHIQ-----KADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
+S + + + + + D++ K + T G +
Sbjct: 12775 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL-----------------TVKAGTNVC 12817
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L +V P P + W K+ ++ + ++ +CTLE+ + DSG YT A N
Sbjct: 12818 LDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 12877
Query: 461 GEASVDCRLEV 471
G S +L+V
Sbjct: 12878 GSKSATIKLKV 12888
Score = 66.2 bits (160), Expect = 6e-11
Identities = 59/222 (26%), Positives = 90/222 (40%), Gaps = 31/222 (13%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-----KADKKTGQWFTVLE 318
I P PP +++ + L W PP++ G + + Y+V+ K W +
Sbjct: 9512 IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNK 9571
Query: 319 R-YHPTTCTISDLIIGNSYSFRVFSENLCGLST-SATVTKELAHIQKADIAAKPKGFIER 376
R T+ DL+ G Y FRV + N G+S SATV Q+ D+ P +
Sbjct: 9572 RDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGP--CDCQRPDM---PPSIDLK 9626
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK-------NKMEIQGNPKYR 429
+F E G + + ++ P P + W K NK + +
Sbjct: 9627 EFMEVEE------------GTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN 9674
Query: 430 ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L CTL I + D+G+YT A+N LG AS + RL V
Sbjct: 9675 KLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9716
Score = 66.2 bits (160), Expect = 6e-11
Identities = 91/429 (21%), Positives = 169/429 (39%), Gaps = 73/429 (17%)
Query: 77 LTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLA 136
+ + VS+ S +SW P+ G + Y++E G + W V++ + TQ V +L
Sbjct: 22251 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-VKRTQIKVTHLT 22309
Query: 137 LGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQI 196
++ RVS+ + G P L+ I E+ P P ++ ++ +
Sbjct: 22310 KYMEYSFRVSSENRFGVSKP--LESAPIIAEHPFVPP-SAPTRPEVYHVSANAMSIRWEE 22366
Query: 197 PFQ-GKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSD-SGRYELTVRVEDLE 254
P+ G K W ++++IL+++ + Y++T VE LE
Sbjct: 22367 PYHDGGSKIIGYWVEKK-------------ERNTILWVKENKVPCLECNYKVTGLVEGLE 22413
Query: 255 -------------------AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGN 295
++ ++ ++ PG P + DV +L W+ P G
Sbjct: 22414 YQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VTDVTRSTVSLIWSAPAYDGG 22470
Query: 296 TELLGYMVQK---ADKKTGQW----FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
++++GY++++ ++ G+W +T++ T +S+ G++Y FRV ++N G+
Sbjct: 22471 SKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSE---GDTYEFRVLAKNAAGV 22527
Query: 349 ------STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
ST ++ KA++ A+ G + T G L
Sbjct: 22528 ISKGSESTGPVTCRDEYAPPKAELDARLHGDLV----------------TIRAGSDLVLD 22571
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
+V P+PKIIW K E+ K T I+ DSG YT N G
Sbjct: 22572 AAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGT 22631
Query: 463 ASVDCRLEV 471
+V ++V
Sbjct: 22632 KAVSVMVKV 22640
Score = 65.1 bits (157), Expect = 1e-10
Identities = 92/432 (21%), Positives = 162/432 (37%), Gaps = 47/432 (10%)
Query: 56 TASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGAS 115
T +P PP PL +T V++ ++W PP + G + Y++E
Sbjct: 18298 TVKVLDRPGPPE-----GPLKVT--GVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL 18350
Query: 116 EWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP--- 172
W VS + + V L G++++ RV AV+ G G P + P+ + P
Sbjct: 18351 SWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEP-LESGPVTACNPYKPPGPP 18408
Query: 173 -----KIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTH-NGHALDSQRVSMRT 224
+ T+ R V G T + + K WT N L R+ +
Sbjct: 18409 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 18468
Query: 225 GDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAA 284
+ R A + +G E + E D L PGPPS+ ++ D + +
Sbjct: 18469 LTEGHSYEFRVAAENAAGVGEPS---EPSVFYRACDALY--PPGPPSNPKVTDTSRSSVS 18523
Query: 285 LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTC-----TISDLIIGNSYSFR 339
L W+ P G + GY+V+ + +W T PT T++ L Y+FR
Sbjct: 18524 LAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP---PTGLQGKQFTVTKLKENTEYNFR 18580
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
+ + N G+ AT+ + ++ + P+ ++ D + +
Sbjct: 18581 ICAINSEGVGEPATLPGSVVAQERIE---PPEIELDADLRKVVVLRASA---------TL 18628
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
+LF +++ P+P++ W K + + + S L I + FDSG Y N
Sbjct: 18629 RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLVIDNVTRFDSGRYNLTLENN 18686
Query: 460 LGEASVDCRLEV 471
G + + V
Sbjct: 18687 SGSKTAFVNVRV 18698
Score = 63.2 bits (152), Expect = 5e-10
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Query: 59 TATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASE 116
T +KP A D P P + VS +TV W PPE G + GY LE + ++
Sbjct: 11885 TESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTR 11944
Query: 117 WVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WVPV+ + + V+NL ++ RV A + G G P++ +P+ ++ IE P
Sbjct: 11945 WVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPP 12000
Score = 63.2 bits (152), Expect = 5e-10
Identities = 53/201 (26%), Positives = 82/201 (40%), Gaps = 5/201 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P L + +S SVT+ WE PE G + GY +E + G S W + +
Sbjct: 23932 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 23991
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIR-ENIEAPKIRVPRHLRQTYIRQ 187
Q T+ L ++ RV A + G P I + + EAP IR + +
Sbjct: 23992 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKE---MKDVTTK 24048
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
+GE L G+P P W G L S++ M + + L + + ++ D G Y
Sbjct: 24049 LGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTC 24108
Query: 247 TVRVEDLEAKAVIDILVIEKP 267
E E + +L+ P
Sbjct: 24109 IATNEVGEVETSSKLLLQATP 24129
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 25/211 (11%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+LV E P P+ + ++DV L W P G + L GY+++ T +W V+
Sbjct: 23132 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT-L 23190
Query: 321 HPTTC--TISDLIIGNSYSFRVFSENLCGLS-----TSATVTKELAHIQKADIAAKPKGF 373
PT T++ L G Y FR+ ++N G+S +A ++L + D++ P+
Sbjct: 23191 KPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKT 23250
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I P+ G +L + P P W +++ + + +
Sbjct: 23251 IH-----VPA------------GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 23293
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
V L IR+ + D+G YT + NV G S
Sbjct: 23294 TKVAKLTIRETTIRDTGEYTLELKNVTGTTS 23324
Score = 61.6 bits (148), Expect = 1e-09
Identities = 33/103 (32%), Positives = 55/103 (53%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + DVS +T++W PPE G + GY++E A WV V+ P+ +T+
Sbjct: 23434 IPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 23493
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
L G ++ RV+A+++ G+G P+ +PI + I P
Sbjct: 23494 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPP 23536
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/104 (32%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV-SARPMMVT 128
VP AP + +++ +S+T++W PE G +Q Y+LE + ++ WV V S RP+ T
Sbjct: 21654 VPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISET 21713
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ V L G+++ V A ++AG GP + + + I RE + P
Sbjct: 21714 RFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPP 21757
Score = 58.5 bits (140), Expect = 1e-08
Identities = 62/272 (22%), Positives = 104/272 (38%), Gaps = 34/272 (12%)
Query: 208 WTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKP 267
WT + + Q +++ Q F R A + G VE EA + + + + P
Sbjct: 10166 WTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPF---VETSEALVIREPITV--P 10220
Query: 268 GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT--- 324
P + + +V L W PP+ G +E++ Y+++ T E++H T
Sbjct: 10221 ERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT-------EKFHKVTNDN 10273
Query: 325 -----CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFS 379
T+ L G++Y +RV + N+ G + TK I D A P + DF
Sbjct: 10274 LLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAPPT--LHLDFR 10328
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
+ T G + L PKPK+ W K++ ++ + + + L
Sbjct: 10329 DKL---------TIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLAL 10379
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
E K DSG Y N G C++ V
Sbjct: 10380 EKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10411
Score = 58.5 bits (140), Expect = 1e-08
Identities = 64/267 (23%), Positives = 100/267 (37%), Gaps = 32/267 (11%)
Query: 207 TWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
TW+ H S + + + F R ++ G E E ++A V
Sbjct: 20914 TWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV-------- 20965
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT 326
P P + + D + L WT P G + + Y+V++ K W TC
Sbjct: 20966 PAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWS---HAGISKTCE 21022
Query: 327 I--SDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
I S L + FRVF++N GLS T+ I ++ P E D S+ P
Sbjct: 21023 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----GPITVKELIITP----EVDLSDIPG- 21073
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
A T G++ L + PKP I W+K+ + ++ + R + TL I+
Sbjct: 21074 ----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNA 21129
Query: 445 SPFDSGVYTCKAINVLGEASVDCRLEV 471
G YT N + CR+ V
Sbjct: 21130 KKEHGGKYTVILDNAV------CRIAV 21150
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPM---- 125
VP AP T+ V+ +S+TV+WE PE G + GY LE+ + W V+ P+
Sbjct: 9819 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 9878
Query: 126 MVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPR 178
+ V L G + RV A+++AG GP ++ P R+ I P P+
Sbjct: 9879 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPK 9931
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/104 (29%), Positives = 52/104 (50%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP AP + DV SV+++W P++ G + GY LE + W + P+ +
Sbjct: 13677 DVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMR 13736
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ RV A++ AG G P++ +P+ + I+ P
Sbjct: 13737 DFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13780
Score = 57.8 bits (138), Expect = 2e-08
Identities = 48/208 (23%), Positives = 79/208 (37%), Gaps = 27/208 (12%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
I+ E+P PP + ++D +A L W P G + + GY+++ K + W +E
Sbjct: 22043 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW---VEAG 22099
Query: 321 H--PTTCTISDLIIGNSYSFRVFSENLCGLST-----SATVTKELAHIQKADIAAKPKGF 373
H T T+ L+ Y FRV ++N G S S+ + KE AD+
Sbjct: 22100 HTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQL 22159
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I T G + + P PK+ W +M ++ + +
Sbjct: 22160 I-----------------TCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTT 22202
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ TL ++ DSG Y N G
Sbjct: 22203 KDRTTLTVKDSMRGDSGRYFLTLENTAG 22230
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/98 (31%), Positives = 44/98 (44%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
+ ++ S+AP+F G + C + P P+I W KN + I +
Sbjct: 26629 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 26688
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ V +LEIR S DSG YT KA N G+ S L V
Sbjct: 26689 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 57.4 bits (137), Expect = 3e-08
Identities = 28/93 (30%), Positives = 44/93 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ L + T G S L C + P P + W + +I+ + ++ + G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
R+ DSG +TC A+N G S C L V+ S
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 57.4 bits (137), Expect = 3e-08
Identities = 55/218 (25%), Positives = 89/218 (40%), Gaps = 27/218 (12%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT-- 324
PGPPS + D + +L W PP G + + GY+V+ ++ T W V E T
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9267
Query: 325 -CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
C + +L Y FRV + N G S + T E I DI +P+ FI+ +
Sbjct: 9268 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGE---IPATDIQEEPEVFIDIGAQDCL- 9323
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIW---------MKNKM-EIQGNPKYRALSE 433
G ++ ++ P PK W MK+ + +I + +
Sbjct: 9324 --------VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAEN 9375
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
V + K S +G Y+ A N G+ + +CR++V
Sbjct: 9376 SSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 9411
Score = 57.0 bits (136), Expect = 4e-08
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 1/153 (0%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P AP T+ V+ S V+W+PP G ++ Y LE + ++W+ V+ + T
Sbjct: 24328 PGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVF 24387
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
+V+NL G ++ RV + G + + +PI + ++ LR +R
Sbjct: 24388 SVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVR-YQS 24446
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMR 223
L G PKP W G + + + R
Sbjct: 24447 NATLVCKVTGHPKPIVKWYRQGKEIIADGLKYR 24479
Score = 56.6 bits (135), Expect = 5e-08
Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
+T +TVT++ +PK S P L D T + +
Sbjct: 26334 TTESTVTRK----------TEPKA--PEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGE 26381
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P+P IW K+ I KY+ ++G LEI K DSG+YTC N G S C+
Sbjct: 26382 PRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCK 26441
Query: 469 LEVKA 473
L +KA
Sbjct: 26442 LTIKA 26446
Score = 55.8 bits (133), Expect = 8e-08
Identities = 57/237 (24%), Positives = 85/237 (35%), Gaps = 46/237 (19%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHP-T 323
+ P PP + + + + W PP G ++++GY+++K K +W E P
Sbjct: 8081 QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL 8140
Query: 324 TCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS 383
T T L G Y FRV +EN G+S + T + D PK +
Sbjct: 8141 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPID---APKVILRTSLE---- 8193
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN--------------------KMEIQ 423
G L S+ SP P I W+K+ K E+Q
Sbjct: 8194 ---------VKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQ 8244
Query: 424 GN-----PKYRAL----SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
P + L S++G L +R D G+Y K N G A C + V
Sbjct: 8245 EEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301
Score = 55.1 bits (131), Expect = 1e-07
Identities = 51/211 (24%), Positives = 84/211 (39%), Gaps = 26/211 (12%)
Query: 258 VIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
++ I I++PG P ++ + D L+W P G + L Y V++ K + W V
Sbjct: 11595 ILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVH 11654
Query: 318 ERYHPTTCTISDLIIGNS-YSFRVFSENLCG----LSTSATVTKELAHIQKADIAAKPKG 372
+ T + D + N Y FRV ++N G + T V KE +QK + K G
Sbjct: 11655 KGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKE--DLQKPVLDLKLSG 11712
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK--MEIQGNPKYRA 430
+ T G + +L VR P P++ W K+K ++ +P+ +
Sbjct: 11713 VL-----------------TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11755
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLG 461
+ + K D G Y A N G
Sbjct: 11756 DTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11786
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PSAP+ LT+ +V SVT+SWEPP G + Y++E RE + T
Sbjct: 18700 DSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEK-RETTRKAYATITNNCTKT 18758
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ NL G + RV A + G G PA +P+ + E
Sbjct: 18759 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE 18797
Score = 54.3 bits (129), Expect = 2e-07
Identities = 42/201 (20%), Positives = 82/201 (40%), Gaps = 13/201 (6%)
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERY 320
+ + EKP PP + + + + +L W P+ G + ++ Y+V+ +K W
Sbjct: 19872 VKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVA- 19930
Query: 321 HPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE 380
T +S L + Y FRVF+EN GLS + + ++ + E D
Sbjct: 19931 KSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPP-------EIDMKN 19983
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
PS T + G + ++ + P PK+ ++ + ++ ++ T+
Sbjct: 19984 FPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTIN 20038
Query: 441 IRKPSPFDSGVYTCKAINVLG 461
+++ D+G Y A N G
Sbjct: 20039 LKESVTADAGRYEITAANSSG 20059
Score = 53.1 bits (126), Expect = 5e-07
Identities = 46/197 (23%), Positives = 82/197 (41%), Gaps = 16/197 (8%)
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTT 324
+ PGP +++ V + ++ W P G + ++GY+V ++ +W V++
Sbjct: 13385 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQ 13442
Query: 325 CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
+ DL G Y+FRV +EN G T + +T + + D+ A + D P
Sbjct: 13443 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV----VARDDVVAP-----DLDLKGLPDL 13493
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
LA S + +L ++ P P + W K + + + + S TL +
Sbjct: 13494 CY-LAKENS----NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 13548
Query: 445 SPFDSGVYTCKAINVLG 461
D+G YT NV G
Sbjct: 13549 QKSDAGKYTITLKNVAG 13565
Score = 53.1 bits (126), Expect = 5e-07
Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 1/118 (0%)
Query: 55 PTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P S A K P VPS P L + V+ S+T+ W PE G + GY++E + +
Sbjct: 19471 PLESVAIKALDPFT-VPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNS 19529
Query: 115 SEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
WV V+ +P+ + L G ++ RV A ++AG P+ I + + P
Sbjct: 19530 LRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 19587
Score = 52.8 bits (125), Expect = 7e-07
Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 19/154 (12%)
Query: 224 TGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNA 283
T + + + + R G Y ++ E +E ++ I I PGPP ++++ DV
Sbjct: 23400 TEGNEYVFRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGM 23451
Query: 284 ALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV------LERYHPTTCTISDLIIGNSYS 337
L W PP+D G +++ GY+V++ + + +W V + RY T L G Y
Sbjct: 23452 TLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRST-----GLTEGLEYE 23506
Query: 338 FRVFSENLCGLSTSATVTKELAHIQKADIAAKPK 371
RV + N G + +K + + KP+
Sbjct: 23507 HRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQ 23540
Score = 52.4 bits (124), Expect = 9e-07
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L + DV+ +S VSW PPE G + Y++E W V+ + T
Sbjct: 12200 DTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPE-VKKT 12258
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V NL G+++ RV+AV+ G G P + +P+ + + P PR L T + +
Sbjct: 12259 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPD--PPRKLEVTEMTKN 12316
Query: 189 GETV 192
T+
Sbjct: 12317 SATL 12320
Score = 52.4 bits (124), Expect = 9e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE+ V+ PGPP S+ + ++ + + W P G +E++GY+V+K D+
Sbjct: 17306 EPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSG 17365
Query: 311 GQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+W R ++ L + Y FRV +EN G+ + T
Sbjct: 17366 IRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17411
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/91 (32%), Positives = 43/91 (47%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP T + H G +T+ +V++ P ++ W N +E+Q + K + GV TLE
Sbjct: 25876 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLE 25935
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
I DSG Y N GEAS L+V
Sbjct: 25936 ILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/287 (21%), Positives = 105/287 (36%), Gaps = 19/287 (6%)
Query: 200 GKPKPQATWTHNGHALDS---QRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAK 256
G PKP W +G L + +VS + L I D+G Y + VR + E
Sbjct: 1061 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1120
Query: 257 AVIDIL------VIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK- 309
A +L ++ K S +L A +Q +T G++ + +K+
Sbjct: 1121 ASASLLEEADYELLMK----SQQEMLYQTQVTAFVQEPKVGETAP----GFVYSEYEKEY 1172
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK 369
+ + ++ T + + + F E L + L + + D K
Sbjct: 1173 EKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEK 1232
Query: 370 PKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR 429
I + F + ++ G C + P PKI W K+ I+ +Y+
Sbjct: 1233 MAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQ 1292
Query: 430 A-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ G +L I P D G+YT A N+ G A +L V+ +A
Sbjct: 1293 MDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAA 1339
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/225 (24%), Positives = 85/225 (37%), Gaps = 30/225 (13%)
Query: 261 ILVIEKPGPPSSIRLL---DVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVL 317
IL ++ GPP+S L + L W P+ G + + GY+++K + V
Sbjct: 8789 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8848
Query: 318 ERYHPTTC-TISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIER 376
+R PTT + +L Y FRV + N G S + P + +
Sbjct: 8849 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSL----------------PLNVVIQ 8892
Query: 377 DFSEAPSFTQPLADHTST----PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D P+ L+ T G + V P PKI W KN+ I+ ++
Sbjct: 8893 DDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQIT 8952
Query: 433 EQGV------CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ V L I K D G YT A N LG + +EV
Sbjct: 8953 KEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T+ DV+ S +SW+ PE G ++ Y +E WV V+ ++
Sbjct: 19779 DTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLS 19838
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+ V NL G + RVS + G G PA + + I E P+
Sbjct: 19839 YK-VTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 19882
Score = 50.8 bits (120), Expect = 3e-06
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P P +T DV+ S T+ W+ P G + YV+E W +S + T
Sbjct: 21950 DTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK---CT 22006
Query: 129 QQ--TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
+Q V +LA G + RVSAV+ G G P + +PI E P+
Sbjct: 22007 RQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPR 22053
Score = 50.4 bits (119), Expect = 3e-06
Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKT 310
E LE++ V+ + P PP + + + + + W P G +E++ Y+V++ DK
Sbjct: 15142 EPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAG 15201
Query: 311 GQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
+W ++ +S L G+ Y FR+ +EN G+S
Sbjct: 15202 QRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGIS 15241
Score = 48.5 bits (114), Expect = 1e-05
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 12/196 (6%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D PS P+ L + +++ SV+++WEPP G ++ Y++E RE +
Sbjct: 16535 DTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK-REATRKSYAAVVTNCHKN 16593
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP-KIRVPRHLRQ----- 182
+ L G + RV+A + G G PA PI + E + P KI V R
Sbjct: 16594 SWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLS 16653
Query: 183 -TYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILF----IRSAQ 237
T G + +Q + + K W+ Q V + LF +
Sbjct: 16654 WTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKG 16713
Query: 238 RSDSGRYELTVRVEDL 253
RSD + + +DL
Sbjct: 16714 RSDPRSLAVPIVAKDL 16729
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
Query: 81 DVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDK 140
D++ SS ++WEPPE G + YVLE G ++PV + ++ TV++L +
Sbjct: 7993 DITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSW-TVKDLIPNGE 8051
Query: 141 FLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ RV AV+ G G L P+ ++ + P
Sbjct: 8052 YFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8083
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/199 (21%), Positives = 75/199 (37%), Gaps = 17/199 (8%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ-KADKKTGQWFTVLERYHP 322
+ +P PP + + ++ +A L W PP G ++ GY+ + +++ +T
Sbjct: 12299 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 12358
Query: 323 TTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAP 382
+ ++ L G Y FRV + N G+S + +E + +A P P
Sbjct: 12359 LSLVVTGLKEGKKYKFRVAARNAVGVS----LPREAEGVYEAKEQLLP-----------P 12403
Query: 383 SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
P T G ++ V P P W K + E+ + L I+
Sbjct: 12404 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12462
Query: 443 KPSPFDSGVYTCKAINVLG 461
+ DSG Y+ A N G
Sbjct: 12463 DVTRKDSGYYSLTAENSSG 12481
Score = 47.4 bits (111), Expect = 3e-05
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELC--REGASEWVPVSARPMM 126
D P+ P+++ + + +S +SW+PP G + YV+E C +EGA EW VS+ +
Sbjct: 24227 DKPTGPIVI--EALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGA-EWQLVSS-AIS 24282
Query: 127 VTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
VT + NL + RVSA ++ G P + + I+ E P
Sbjct: 24283 VTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP 24328
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
DVP P + + DVS SV ++W P G + Y++E C A W+ V T
Sbjct: 24623 DVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG--QARET 24680
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
+ TV NL + RV A + G P+ +P +E+
Sbjct: 24681 RYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKED 24720
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 83 SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP-----MMVTQQTVRNLAL 137
+ S+ VSW PP G + GY LE EG+ W VS P + + V L
Sbjct: 9114 TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9173
Query: 138 GDKFLLRVSAVSSAGAGPPAMLDQP 162
G K+ R A+++AG GPP+ P
Sbjct: 9174 GVKYQFRAMAINAAGIGPPSEPSDP 9198
Score = 47.0 bits (110), Expect = 4e-05
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 14/144 (9%)
Query: 61 TKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPV 120
T P PPS + +V+ S+TV W P G + GY LE+ + W
Sbjct: 20171 TTPGPPSTP--------WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKA 20222
Query: 121 SARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHL 180
+ + T V ++ G + RV A ++AG G P+ +P+ + E PR++
Sbjct: 20223 NKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP-----PRNV 20277
Query: 181 RQTYIRQVGETVNLQIP-FQGKPK 203
R T I + +++ Q P F G K
Sbjct: 20278 RITDISKNSVSLSWQQPAFDGGSK 20301
Score = 47.0 bits (110), Expect = 4e-05
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
T P P E + P +L DV+ SSV++SW P+ G + GY +E +WV
Sbjct: 23824 TPKTPLNPPEPPSNPPEVL---DVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWV 23880
Query: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ + T TV L ++ R+ A + G + +P+ ++ + P
Sbjct: 23881 RHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKP 23934
Score = 46.6 bits (109), Expect = 5e-05
Identities = 39/129 (30%), Positives = 52/129 (40%), Gaps = 10/129 (7%)
Query: 355 TKELAHIQKADIAA---------KPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405
TKEL +K +A KP EAP + + T G V
Sbjct: 1996 TKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRV 2055
Query: 406 RASPKPKIIWMKNKMEIQGNPK-YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
P P+ W KN ++I+ + + Y E VC L IR + DS KAIN+ GE S
Sbjct: 2056 VGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETS 2115
Query: 465 VDCRLEVKA 473
L V+A
Sbjct: 2116 SHAFLLVQA 2124
Score = 46.6 bits (109), Expect = 5e-05
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ---GNPKYRALSEQGVCT 438
P FT PL + T+ G + + ++ P+P + W K+ +I+ + KY S++G+
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L I + D YT A N GE S +L V
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/76 (31%), Positives = 36/76 (47%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G+ + C ++++P + W K EI + K S + + +LEI + D G YTCK
Sbjct: 4351 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 4410
Query: 456 AINVLGEASVDCRLEV 471
A N G S L V
Sbjct: 4411 ASNEYGSVSCTATLTV 4426
Score = 46.2 bits (108), Expect = 6e-05
Identities = 42/153 (27%), Positives = 61/153 (39%), Gaps = 3/153 (1%)
Query: 20 ESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTL 79
E A++ TAE + + E R K A TA DVP P L +
Sbjct: 9366 EDAQLETAENSSVIIIPECKRSH-TGKYSITAKNKAGQKTANCRVKVM-DVPGPPKDLKV 9423
Query: 80 DDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGD 139
D++ S +SW+ P+ G ++GYV+E W V+ T V +L
Sbjct: 9424 SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNP-DCGSTTFVVPDLLSEQ 9482
Query: 140 KFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
++ RV A + G GPP Q R+ I P
Sbjct: 9483 QYFFRVRAENRFGIGPPVETIQRTTARDPIYPP 9515
Score = 46.2 bits (108), Expect = 6e-05
Identities = 24/88 (27%), Positives = 43/88 (48%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQ 129
+P P L + +++ S+TV W P+ G + GY++E W+ + R + +
Sbjct: 17321 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR 17380
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPA 157
V L ++ RVSA ++AG G P+
Sbjct: 17381 LRVTGLTEDHEYEFRVSAENAAGVGEPS 17408
Score = 46.2 bits (108), Expect = 6e-05
Identities = 27/102 (26%), Positives = 48/102 (47%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
PSAP + VS++++++ WE P G + GY +E WV + P +
Sbjct: 22344 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22403
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
V L G ++ R A+++AG + +PI + ++AP
Sbjct: 22404 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP 22445
Score = 45.8 bits (107), Expect = 8e-05
Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 17/123 (13%)
Query: 241 SGRYELTVRVED---LEAKAVIDILVIEKP----GPPSSIRLLDVWGCNAALQWTPPQDT 293
+G+YE VR + + + D +VI+ P GPP ++L + + WTPP D
Sbjct: 9069 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 9128
Query: 294 GNTELLGYMVQKADKKTGQWFTVLERYHPTT--------CTISDLIIGNSYSFRVFSENL 345
G + + GY ++K ++ + W V P T + L+ G Y FR + N
Sbjct: 9129 GGSPITGYWLEKREEGSPYWSRVSRA--PITKVGLKGVEFNVPRLLEGVKYQFRAMAINA 9186
Query: 346 CGL 348
G+
Sbjct: 9187 AGI 9189
Score = 45.8 bits (107), Expect = 8e-05
Identities = 60/300 (20%), Positives = 105/300 (35%), Gaps = 40/300 (13%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ V G+P P+ W N + S VS+ L IR+A SDSG+Y +
Sbjct: 26651 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 26710
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG----YMV 303
+ + A ++V+ PS +L + +G+T L G V
Sbjct: 26711 AKNFRGQCSATASLMVLPLVEEPSREVVL--------------RTSGDTSLQGSFSSQSV 26756
Query: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSF--------RVFSENLCGLSTSATVT 355
Q + K F+ ++ T ++ S + S + G+S +
Sbjct: 26757 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 26816
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIW 415
+ + KA I P P +D + G + C+ P P++ W
Sbjct: 26817 SSTSKMLKAGIRGIP-----------PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTW 26865
Query: 416 M--KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
K+ Q ++ + + TL I D G+YT N G S + +++
Sbjct: 26866 SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 26925
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 50 PAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P P + K D P P++ +DV+S+S+ V W P+ G + GY LE
Sbjct: 8388 PGPPCVSKPLVAKDPFGPPDAPDKPIV---EDVTSNSMLVKWNEPKDNGS-PILGYWLEK 8443
Query: 110 CREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENI 169
++ W V+ + + V L G ++ RV A ++AG G + P + I
Sbjct: 8444 REVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPI 8503
Query: 170 EAPKIRVPR 178
P +PR
Sbjct: 8504 SPPGPPIPR 8512
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/93 (30%), Positives = 41/93 (44%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E P Q L T G + + P+PKI W K + + K + L + TL
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + P D+ VYTC+A N G A+ L V+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 1/73 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+PL D T G + L C V + K+ W KN EI + KY +++ V L I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5848
Query: 444 PSPFDSGVYTCKA 456
+P D YTC A
Sbjct: 5849 CTPEDIKTYTCDA 5861
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGVCTL 439
P F + L + G ++ +P P I+W+KN I + PK R +G L
Sbjct: 1510 PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL 1569
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+I DS YT AIN G + C++ V+ A
Sbjct: 1570 KIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFA 1606
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/284 (20%), Positives = 102/284 (35%), Gaps = 42/284 (14%)
Query: 200 GKPKPQATWTHNGHALDSQRVSMRTGDQDS-ILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
G+P+P A WT +G A+ + D+ L I SDSG Y TV+
Sbjct: 26380 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--------- 26430
Query: 259 IDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
G SS L + + +TE QK + T Q V++
Sbjct: 26431 ------NSAGSVSSSCKLTI------------KAIKDTEAQKVSTQKTSEITPQKKAVVQ 26472
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
S+ I + S+ L A+ ++K+ + K + +
Sbjct: 26473 EEISQKALRSEEIKMSEAK----SQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 26528
Query: 379 SEAPSFTQPLADHTSTPGYSTQ--------LFCSVRASPKPKIIWMKNKMEIQGNPKYRA 430
++ ++ + H +STQ L + + W+ N +E+ + +YR
Sbjct: 26529 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 26588
Query: 431 LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
TL I++ S D G+ TC I+ E V C+ ++ S
Sbjct: 26589 GVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDLTLS 26630
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 379 SEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN--PKYRALSEQGV 436
++AP+FTQPL G + + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
L I + +SG Y+ KA N G+A+ L VKA A
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA 102
Score = 43.5 bits (101), Expect = 4e-04
Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 9/129 (6%)
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408
S+S + T+E+A ++ I G I+ D P PL D S G L S+ +
Sbjct: 4216 SSSESGTEEVATVK---IQEAEGGLIKED---GPMIHTPLVDTVSEEGDIVHLTTSITNA 4269
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFD-SGVYTCKAINVLGEASVDC 467
+ + W + + K++ L +Q TL I K + D G Y C+A+N G+ +
Sbjct: 4270 KE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4327
Query: 468 RLEVKASAA 476
+L V AA
Sbjct: 4328 KLTVVKRAA 4336
Score = 43.1 bits (100), Expect = 5e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+F Q L T G +L V P P + + ++ EIQ + ++ E + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ P DSG Y+ A N +G A+ L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ PL D ++ G + C V + K+ W +I+ + +R + LEI
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
+ P D G YT A N +G+ S L ++A
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3389
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRAL-SEQGVCTLE 440
P F + L G +V P P + W K ++ + Y + + G T
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ P DSG+Y CKA N+LGE++ L V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 54 APTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREG 113
AP S A P ++ P P + +S + V W P G + GY LE +
Sbjct: 17992 APLDSKAVIVQYPFKE-PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
+ WV ++ P+ T+ L G ++ +VSA + G G P+ + + R+ + P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18109
Score = 41.2 bits (95), Expect = 0.002
Identities = 67/326 (20%), Positives = 116/326 (35%), Gaps = 44/326 (13%)
Query: 156 PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL 215
P I + ++EAPKI ++ + Q G + ++ GKP P+ W NG +
Sbjct: 2016 PTFKPDKIELSPSMEAPKIF--ERIQSQTVGQ-GSDAHFRVRVVGKPDPECEWYKNGVKI 2072
Query: 216 DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRL 275
+ +D++ EL +R E A I + I G SS
Sbjct: 2073 ERSDRIYWYWPEDNVC-------------ELVIRDVTAEDSASIMVKAINIAGETSSHAF 2119
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
L V T EL + ++ D E + + +
Sbjct: 2120 LLVQAKQLI--------TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEG 2171
Query: 336 YSFRVFSE------NLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLA 389
+R+ S+ ++ + TS ++ ++ K +E E F + L
Sbjct: 2172 DKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVE---FVKELQ 2228
Query: 390 DHTSTPGYSTQLFCSVRASPKPKII---WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
D YS +L C V P+ I W N +E++ N KY S +G L ++ +
Sbjct: 2229 DIEVPESYSGELECIV----SPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTK 2284
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y+ V+ C+L++K
Sbjct: 2285 EDQGEYSF----VIDGKKTTCKLKMK 2306
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/285 (21%), Positives = 104/285 (36%), Gaps = 56/285 (19%)
Query: 202 PKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVID 260
P + W +G L + + + L I + + D G Y V AK ++
Sbjct: 2600 PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVE 2659
Query: 261 ILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWF---TVL 317
+ I+K +++ L V T QD T L + + K QW VL
Sbjct: 2660 AVKIKK-----TLKNLTV---------TETQDAVFTVELTH----PNVKGVQWIKNGVVL 2701
Query: 318 ERYHPTTCTISDLIIGNSYSFRV-----FSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
E ++ G YS R+ E++ G H++ I KPK
Sbjct: 2702 ESNEKYAISVK----GTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPK- 2756
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
D T+ + SV P + W +EI+ + K+R +S
Sbjct: 2757 -----------------DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVS 2798
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
E+ V L ++ SP D+G YT V+G+ ++C+ ++ H
Sbjct: 2799 ERKVHKLMLQNISPSDAGEYTA----VVGQ--LECKAKLFVETLH 2837
Score = 40.4 bits (93), Expect = 0.004
Identities = 19/61 (31%), Positives = 29/61 (47%)
Query: 412 KIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
++ W +++ + KY E GV L ++ + D G Y CK +N GE S L V
Sbjct: 25102 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161
Query: 472 K 472
K
Sbjct: 25162 K 25162
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/126 (24%), Positives = 44/126 (34%), Gaps = 6/126 (4%)
Query: 350 TSATVTKELAHIQKADIAAKPKGFIERDFSE----APSFTQPLADHTSTPGYSTQLFCSV 405
T T+E ++ D+ E AP F G S C V
Sbjct: 1000 TEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV 1059
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRAL--SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+PKP + W K+ + + +Y+ + G C L I D+G YT N GE
Sbjct: 1060 GGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGET 1119
Query: 464 SVDCRL 469
S L
Sbjct: 1120 SASASL 1125
Score = 40.0 bits (92), Expect = 0.005
Identities = 41/151 (27%), Positives = 63/151 (41%), Gaps = 11/151 (7%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P L L D++ SVT+ W+ P G + Y++E RE + +
Sbjct: 14369 DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEK-REATRKSYSTATTKCHKC 14427
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
V L+ G ++ RV A + G G P +P+ + EAP P L I +
Sbjct: 14428 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPV---KASEAPS--PPDSLNIMDITK- 14481
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR 219
TV+L P KPK G+ +++QR
Sbjct: 14482 -STVSLAWP---KPKHDGGSKITGYVIEAQR 14508
Score = 39.3 bits (90), Expect = 0.008
Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQR---VSMRTGDQDSILFIRSAQR 238
Q+ + G T + G P P+ +W +G + + V + D + L I + +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 239 SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLL 276
++SGRY L +A + ++LV + PP+ ++ L
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110
Score = 38.5 bits (88), Expect = 0.014
Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 26/144 (18%)
Query: 172 PKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSIL 231
P+ +P + + Y VGE V + P+P TW +G ++ GD D
Sbjct: 25193 PEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQ-------KIKPGDNDK-- 25240
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT--- 288
+ SD G Y+LT+ + A ++ K G S C A L T
Sbjct: 25241 --KYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS---------CKAKLTVTLHP 25289
Query: 289 PPQDTGNTELLGYMVQKADKKTGQ 312
PP D+ + ++ A+ + GQ
Sbjct: 25290 PPTDSTLRPMFKRLLANAECQEGQ 25313
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 1/97 (1%)
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE-QG 435
D + P F + LA+ G S V P P + W K+ + P + E
Sbjct: 25293 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLD 25352
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
L IR P D+G Y A N G S L+V+
Sbjct: 25353 YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389
Score = 37.7 bits (86), Expect = 0.023
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 4/80 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
GE+ G+P P TW G L S R + T S I S Q SD G Y +
Sbjct: 26078 GESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNY--S 26135
Query: 248 VRVEDLEAKAVIDI-LVIEK 266
V VE+ E K + L I+K
Sbjct: 26136 VVVENSEGKQEAEFTLTIQK 26155
Score = 36.6 bits (83), Expect = 0.051
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 267 PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTC 325
PG P + V + + W P+ G + + GY ++ D + +W V + T
Sbjct: 9820 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 9879
Query: 326 TIS----DLIIGNSYSFRVFSENLCGLSTSA 352
+S LI G+ Y FRV++ N G+ ++
Sbjct: 9880 GVSYKVTGLIEGSDYQFRVYAINAAGVGPAS 9910
Score = 36.6 bits (83), Expect = 0.051
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 65 PPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARP 124
PP D P P + T ++ S+ V W P+ G + Y++E + W+ + +
Sbjct: 15157 PP--DPPKNPEVTT---ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 15211
Query: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPA 157
+ + V L G ++ R+ A ++AG P+
Sbjct: 15212 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15244
Score = 35.8 bits (81), Expect = 0.088
Identities = 18/64 (28%), Positives = 30/64 (46%)
Query: 409 PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468
P + W+ + ++ + R ++E G C+L+ DSG+ TC+A N G
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745
Query: 469 LEVK 472
L VK
Sbjct: 1746 LIVK 1749
Score = 35.8 bits (81), Expect = 0.088
Identities = 26/104 (25%), Positives = 43/104 (41%)
Query: 370 PKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR 429
P F P F + +++ + G L +V PKPKI W N + + + Y+
Sbjct: 3445 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3504
Query: 430 ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
+ + +L I D G YTC A N G+ L++ +
Sbjct: 3505 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3548
Score = 35.8 bits (81), Expect = 0.088
Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 3/134 (2%)
Query: 42 EQVPKPQAPAPQAPTASTATKP--APPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGR 99
E + + +A P ++P A S +PS P + + + W PE G
Sbjct: 22712 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22771
Query: 100 LGLQGYVLELCREGASEWVPVSARPMMV-TQQTVRNLALGDKFLLRVSAVSSAGAGPPAM 158
+ Y+++ + + W V+ ++ T+ V +L G + RV+AV++AG P+
Sbjct: 22772 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22831
Query: 159 LDQPIHIRENIEAP 172
I RE P
Sbjct: 22832 ASNFISCREPSYTP 22845
Score = 35.8 bits (81), Expect = 0.088
Identities = 54/291 (18%), Positives = 98/291 (33%), Gaps = 34/291 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ + Q KP + W HNG L +S ++ L I DSG Y
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRA- 25949
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
+ G S LDV G + + +D ++
Sbjct: 25950 --------------VCTNYKGEASDYATLDVTGGDYTTYASQRRD-----------EEVP 25984
Query: 308 KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS------ENLCGLSTSATVTKELAHI 361
+ T E Y ++ + + +S V S E+L SA+ + A +
Sbjct: 25985 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26044
Query: 362 QKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
++ + K + A T+P + T G S + C P P + W++
Sbjct: 26045 EEKSLEEKSTTRKIKTTLAARILTKPRS-MTVYEGESARFSCDTDGEPVPTVTWLRKGQV 26103
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ + +++ + + T EI D G Y+ N G+ + L ++
Sbjct: 26104 LSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 35.0 bits (79), Expect = 0.15
Identities = 37/142 (26%), Positives = 56/142 (39%), Gaps = 14/142 (9%)
Query: 313 WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKG 372
WF + H T+ T+ G ++ + L +S KEL+ + +
Sbjct: 5109 WFKNDAKLH-TSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKV------ 5161
Query: 373 FIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
+E D P FT L D T+ L C V S + W K+ EI +PKY +
Sbjct: 5162 -LEAD----PYFTVKLHDKTAVEKDEITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIKA 5214
Query: 433 EQGVCTLEIRKPSPFDSGVYTC 454
+ L+I+K D G Y C
Sbjct: 5215 DGLRRILKIKKADLKDKGEYVC 5236
Score = 35.0 bits (79), Expect = 0.15
Identities = 63/289 (21%), Positives = 114/289 (39%), Gaps = 40/289 (13%)
Query: 173 KIRVPRHLRQTYIRQVGETV-NLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSI 230
K+R+ L+ T +++ E V N ++ +G +A W N A+ DS + + D
Sbjct: 6142 KLRIVVPLKDTRVKEQQEVVFNCEVNTEGA---KAKWFRNEEAIFDSSKYIILQKDLVYT 6198
Query: 231 LFIRSAQRSDSGRYELTVRVEDLE-AKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
L IR A D Y +++ E K+ +++V E+ +R+++ P
Sbjct: 6199 LRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEE-----DLRIVE-----------P 6242
Query: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPT---TCTISDLIIGNSYSFRVFSENLC 346
+D ++ +KK+ ++ + R + T T ++ N S+RV
Sbjct: 6243 LKD----------IETMEKKSVTFWCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHM 6292
Query: 347 GLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS-FTQPLADHTSTPGYSTQLFCSV 405
E +I A + K E EAP+ F + L D T T + +F
Sbjct: 6293 LTIKDCGFPDEGEYIVTA---GQDKSVAELLIIEAPTEFVEHLEDQTVTE-FDDAVFSCQ 6348
Query: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
+ K + W +N EI+ KY+ + + L I+ D Y C
Sbjct: 6349 LSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 6397
Score = 34.7 bits (78), Expect = 0.20
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTC 454
G + + V P P+ W + +I + ++ + E G +L I +P DSG +T
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTV 1484
Query: 455 KAINVLGEASVDCRLEVKA 473
A N G +S+ L V+A
Sbjct: 1485 VAQNRAGRSSISVILTVEA 1503
Score = 34.7 bits (78), Expect = 0.20
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
E FT+ LA+ + + +L C V + P ++IW K EI +Y L+E L
Sbjct: 5964 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 6022
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I+ D+G Y C+ L + D +++V AA
Sbjct: 6023 VIQNAHLEDAGNYNCR----LPSSRTDGKVKVHELAA 6055
Score = 34.3 bits (77), Expect = 0.26
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI--LFIRSAQRSDSGRY 244
GE+V L+ G P P TW + ++S + + Q I L IR A DSGR+
Sbjct: 911 GESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARLMIREAFAEDSGRF 967
Score = 34.3 bits (77), Expect = 0.26
Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
D P + + +VS SVT++WE P G + Y++E RE A T
Sbjct: 23039 DTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEK-REAAMRAFKTVTTKCSKT 23097
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRE 167
+ L G + RV + G G P + + E
Sbjct: 23098 LYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 23136
Score = 33.9 bits (76), Expect = 0.33
Identities = 55/255 (21%), Positives = 94/255 (36%), Gaps = 49/255 (19%)
Query: 208 WTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
WT NG + RVS R +L I+ D G Y +T + K+V ++L+IE
Sbjct: 6269 WTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQD----KSVAELLIIEA 6324
Query: 267 PGP------PSSIRLLD--VWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
P ++ D V+ C + + + N G +++ K + +
Sbjct: 6325 PTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRN----GREIKEGKKYKFEKDGSIH 6380
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
R C + D E CG+ D ++ + F+E
Sbjct: 6381 RLIIKDCRLDDEC-----------EYACGVE---------------DRKSRARLFVE--- 6411
Query: 379 SEAP-SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
E P +P D PG +F + K ++ W++N M + K++ +SE +
Sbjct: 6412 -EIPVEIIRPPQDILEAPGADV-VFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIH 6469
Query: 438 TLEIRKPSPFDSGVY 452
L+I P D G Y
Sbjct: 6470 RLQICDIKPRDQGEY 6484
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 4/77 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G+T + G+P P+ W H+G + D + D L I A SDSG E
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG--EW 1482
Query: 247 TVRVEDLEAKAVIDILV 263
TV ++ ++ I +++
Sbjct: 1483 TVVAQNRAGRSSISVIL 1499
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G + + C V P+PK+ W N I+ + ++R + G+ L+I +D+G
Sbjct: 1809 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1867
Query: 456 AINVLGEASVDCRLEVK 472
A N G +LE++
Sbjct: 1868 AENPEGVIEHKVKLEIQ 1884
Score = 30.4 bits (67), Expect = 3.7
Identities = 63/326 (19%), Positives = 120/326 (36%), Gaps = 54/326 (16%)
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T ++L++ D +RV A+ + +L+ + + Q Y +
Sbjct: 5489 TFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKL------------QDYTGVEKD 5536
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
V LQ P W +G + S+ ++ + +L ++ A +SD G+Y
Sbjct: 5537 EVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCG 5595
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLG-YMVQKAD- 307
+ K I+ I+ P S+ +++ + + N +L G ++Q D
Sbjct: 5596 TDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDC 5655
Query: 308 --KKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQ-KA 364
K+ G+ I L++ N C L + V + A+++ A
Sbjct: 5656 EIKEEGK--------------IHSLVLHN-----------CRLDQTGGVDFQAANVKSSA 5690
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
+ KP+ +PL D T T G + C + P ++K K +++
Sbjct: 5691 HLRVKPR---------VIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGK-KLEP 5740
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSG 450
+ K SE V TL +R D+G
Sbjct: 5741 SDKVVPRSEGKVHTLTLRDVKLEDAG 5766
Score = 30.4 bits (67), Expect = 3.7
Identities = 34/160 (21%), Positives = 60/160 (37%), Gaps = 10/160 (6%)
Query: 13 SPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDV-- 70
S ET E EV+ SE+ E +PK T + + + +V
Sbjct: 8936 SKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHV 8995
Query: 71 -----PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL--CREGASEWVPVSAR 123
PS P L + D+ + S ++W+ P G + YV++ +EW V+
Sbjct: 8996 EVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT-N 9054
Query: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
+ + + L ++ RV AV+ G D+ +
Sbjct: 9055 TAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 9094
Score = 30.0 bits (66), Expect = 4.8
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F +PL D + C + + K+ W K+ EI+ KY +S+ V L I K
Sbjct: 5879 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937
Query: 444 PSPFDSGVYTCK 455
D Y+C+
Sbjct: 5938 CLLDDEAEYSCE 5949
Score = 29.3 bits (64), Expect = 8.2
Identities = 20/86 (23%), Positives = 33/86 (38%), Gaps = 4/86 (4%)
Query: 387 PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSP 446
PL D G L C V + W N +I+ + + +A+ + L I +
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463
Query: 447 FDSGVYTCKAINVLGEASVDCRLEVK 472
D G Y ++G +C L V+
Sbjct: 2464 SDEGPYKL----IVGRVETNCNLSVE 2485
>gi|140560917 myomesin 1 isoform b [Homo sapiens]
Length = 1589
Score = 87.8 bits (216), Expect = 2e-17
Identities = 96/430 (22%), Positives = 163/430 (37%), Gaps = 48/430 (11%)
Query: 55 PTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P+ +T D+P AP + + +SV VSWE E L GY +E G+
Sbjct: 723 PSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGS 780
Query: 115 SEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK- 173
+W P + P+ ++ T L G ++ RV AV++AG + + I ++ I P
Sbjct: 781 GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSP 840
Query: 174 ---IRVPRHLRQTYI------------RQVGETVNLQIPFQGKPKPQATWTH-NGHALDS 217
I R + + G VN + G P W N A+
Sbjct: 841 PCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVP---GKWREANVKAVSE 897
Query: 218 QRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLD 277
+ + ++ + + A + +G + E + + I PGPP S++ +
Sbjct: 898 EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEE----WTIAVPGPPHSLKCSE 953
Query: 278 VWGCNAALQWTPPQDTGNTELLGYMV--QKADKKTGQWFTVLE-RYHPTTCTISDLIIGN 334
V + LQW PP +G T + GY V ++A K QW + E + L G
Sbjct: 954 VRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGV 1013
Query: 335 SYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTST 394
SY FRV + N G+ KP +E T+ + +
Sbjct: 1014 SYVFRVRAINQAGV-------------------GKPSDLAGPVVAETRPGTKEVVVNVDD 1054
Query: 395 PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
G + F + +PK + W K+ + + +P+ S+ + + D G+Y+C
Sbjct: 1055 DGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSC 1114
Query: 455 KAINVLGEAS 464
+ G AS
Sbjct: 1115 DVTDTDGIAS 1124
Score = 83.6 bits (205), Expect = 4e-16
Identities = 85/329 (25%), Positives = 137/329 (41%), Gaps = 38/329 (11%)
Query: 52 PQAP-TASTATKPAPPSED-VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P AP T PSE VP P L++ + + S V +SW+PP + G G+ Y +E
Sbjct: 617 PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
Query: 110 CREGASEWVPVSAR-PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
C G W V+ P+ + + +LA G + RV +SAG G P+ + + +
Sbjct: 676 CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
Query: 169 IEAPKIR---VPRHLRQTYI-----------RQVGETVNLQIPFQGKPKPQATWTHNGHA 214
++ PK +P T + VG + + GK +P N +
Sbjct: 736 LDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEP-----CNNNP 790
Query: 215 LDSQRVS---MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPS 271
+ R + + TG Q I +R+ + +G E + E +E KA I P PP
Sbjct: 791 VKGSRFTCHGLVTG-QSYIFRVRAV--NAAGLSEYSQDSEAIEVKA-----AIAPPSPPC 842
Query: 272 SIRLLDVWGCNAALQWTPPQDTGNTELLGYMV---QKADKKTGQWFTV-LERYHPTTCTI 327
I L+ + + L W P G E+ GY V + D G+W ++ I
Sbjct: 843 DITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKI 902
Query: 328 SDLIIGNSYSFRVFSENLCGLSTSATVTK 356
S+L Y F+V + N+ GL + V++
Sbjct: 903 SNLKENMVYQFQVAAMNMAGLGAPSAVSE 931
Score = 72.8 bits (177), Expect = 6e-13
Identities = 65/305 (21%), Positives = 109/305 (35%), Gaps = 71/305 (23%)
Query: 68 EDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
E P+APL + + + + +SW+ P G + GY ++ C G W + P+
Sbjct: 507 EGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF 566
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ V L G ++ RV AV+ G G P+ + +P+ + E ++
Sbjct: 567 ARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARL------------- 613
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
K +P A WT G+ +T
Sbjct: 614 -------------KSRPSAPWT--------------------------------GQIIVT 628
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
E+ ++ ++ PGPP+ + + + L W PP G+ ++ Y V+K +
Sbjct: 629 ---EEEPSEGIV-------PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
Query: 308 KKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
T W V + DL G SY FRV N G+ + T+ K D
Sbjct: 678 AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
Query: 366 IAAKP 370
I P
Sbjct: 738 IPKAP 742
Score = 57.0 bits (136), Expect = 4e-08
Identities = 85/414 (20%), Positives = 159/414 (38%), Gaps = 56/414 (13%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASE--WVPVSARPMMV 127
VP P L +V S+ + W+PP GR + GY ++L A E W ++ +
Sbjct: 942 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1001
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
VR L G ++ RV A++ AG G P+ L P+ + R + +
Sbjct: 1002 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV----------VAETRPGTKEVVVN 1051
Query: 188 VGETVNLQIPFQGK---PKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGR 243
V + + + F+ PK + +W+ + + DS R+ + + + + + D G
Sbjct: 1052 VDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGI 1111
Query: 244 YELTVR----------VEDLEAKAVIDILVIEK--PGPPSSIRLLDVWGCNAALQWTPPQ 291
Y V +++ E K ++ + K P S +++ W +
Sbjct: 1112 YSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAE 1171
Query: 292 DTGNTELLGYMVQKA------------DKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR 339
+ Y+ + D+ TG +E+ +Y+F+
Sbjct: 1172 KLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDED--------EGTYTFQ 1223
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
+ ST V +QK + + + +I + + P F + L+ T +
Sbjct: 1224 LQDGKATNHSTVVLVGDVFKKLQK-EAEFQRQEWIRK---QGPHFVEYLSWEV-TGECNV 1278
Query: 400 QLFCSVRASPKPK-IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVY 452
L C V K I+W K++ EI + K+ + G+CTL I + S D+G+Y
Sbjct: 1279 LLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIY 1330
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/95 (34%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK--MEIQGNP-KYRALSEQGVC 437
AP F HT + +L CS+ P+P++ W KN+ + + NP KY S G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 438 TLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
TLEI D+ Y A+NV GE S + VK
Sbjct: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 50.8 bits (120), Expect = 3e-06
Identities = 41/175 (23%), Positives = 75/175 (42%), Gaps = 11/175 (6%)
Query: 203 KPQATWTHNGHALDSQR--VSMRTGDQDSILFIRSAQRSDSGRYELTVRV----EDLEAK 256
+P+ W NG L + ++ +G++ ++ F + D G Y + VR+ E A
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496
Query: 257 AVI---DILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW 313
+ D + P P ++ L+ + W P G + +LGY + K + T W
Sbjct: 497 VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
Query: 314 FTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIA 367
+ ++ LI G SY FRV + N G+ + V++ +A + A+ A
Sbjct: 557 SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKA 611
Score = 33.5 bits (75), Expect = 0.44
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTGD 226
E + RV L Q G+ +NL G P P+ +W N AL D + G
Sbjct: 1472 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG- 1530
Query: 227 QDSILFIRSAQRSDSGRYELTVR 249
+ + I +DSG+Y L V+
Sbjct: 1531 RTAYFTINGVSTADSGKYGLVVK 1553
Score = 32.7 bits (73), Expect = 0.74
Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 1/81 (1%)
Query: 392 TSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-VCTLEIRKPSPFDSG 450
T G + L C+V P P++ W+KN+ + + E G I S DSG
Sbjct: 1487 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1546
Query: 451 VYTCKAINVLGEASVDCRLEV 471
Y N G + D + V
Sbjct: 1547 KYGLVVKNKYGSETSDFTVSV 1567
>gi|155969693 myomesin family, member 3 [Homo sapiens]
Length = 1437
Score = 82.0 bits (201), Expect = 1e-15
Identities = 90/353 (25%), Positives = 147/353 (41%), Gaps = 38/353 (10%)
Query: 52 PQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEP---PERLGRLGLQGYVLE 108
P P+ A + PP+ P A + D + +SV+++W+P PE LG Y +
Sbjct: 586 PSEPSEPIALR-GPPATLPPPAQVQAFRD--TQTSVSLTWDPVKDPELLG------YYIY 636
Query: 109 LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
+ G SEW V+ +P+ T+ TV L G ++ V +VS AG G + +PI +++
Sbjct: 637 SRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQA 696
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQ---GKPKPQATWTHNG-----HALDSQRV 220
+ P P + + + P + GK H+ HA++ Q +
Sbjct: 697 LATPS--APYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPI 754
Query: 221 SMRTGDQDSI-----LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRL 275
R + R+ + +G EL+ E K + +PGPP +R
Sbjct: 755 PTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKE----WTMPQPGPPYDVRA 810
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE-RYHPTTCTISDLIIGN 334
+V + LQW PP G + GY V ++ + QW V T +SDL G
Sbjct: 811 SEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGK 870
Query: 335 SYSFRVFSENLCGLS-----TSATVTKELAHIQKADIAAKPKGFIERDFSEAP 382
SY F+V + N GL T + ++ + ++ +GFI F EAP
Sbjct: 871 SYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEVGVDEEGFIYLAF-EAP 922
Score = 74.3 bits (181), Expect = 2e-13
Identities = 75/320 (23%), Positives = 129/320 (40%), Gaps = 30/320 (9%)
Query: 46 KPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY 105
K + P + +T + +PS P + ++ + V ++WE P R L Y
Sbjct: 476 KTEIPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLT-Y 534
Query: 106 VLELCREGASEWVPVSAR-PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIH 164
LE G+ W +S+ P+ + V +L ++ RV A++ G P+ +PI
Sbjct: 535 SLEKSVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIA 594
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPK-----------PQATW-THNG 212
+R P +P + R +V+L P+ + W T N
Sbjct: 595 LR----GPPATLPPPAQVQAFRDTQTSVSLTWDPVKDPELLGYYIYSRKVGTSEWQTVNN 650
Query: 213 HALDSQRVS---MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGP 269
+ R + +RTG + +RS S++G E + E + K + P
Sbjct: 651 KPIQGTRFTVPGLRTGKEYEFC-VRSV--SEAGVGESSAATEPIRVKQAL-----ATPSA 702
Query: 270 PSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPT-TCTIS 328
P LL+ + W PP+ G ++LGY + + D + W V ++ PT C +S
Sbjct: 703 PYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVS 762
Query: 329 DLIIGNSYSFRVFSENLCGL 348
DL G+ Y FR + N G+
Sbjct: 763 DLHEGHFYEFRARAANWAGV 782
Score = 72.8 bits (177), Expect = 6e-13
Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 14/191 (7%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P P + +V ++S+ + WEPP +G + GY + EG+ +W PV+ P+ T
Sbjct: 802 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHL 861
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
V +L G ++ +V A++SAG G P+M P+ + + A +I V V E
Sbjct: 862 RVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEV----------GVDE 911
Query: 191 TVNLQIPFQGKPKPQAT---WTHNGHA-LDSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
+ + F+ P ++ W+ + LD QRV + S + ++ D G Y +
Sbjct: 912 EGFIYLAFEAPEAPDSSEFQWSKDYKGPLDPQRVKIEDKVNKSKVILKEPGLEDLGTYSV 971
Query: 247 TVRVEDLEAKA 257
V D + A
Sbjct: 972 IVTDADEDISA 982
Score = 66.6 bits (161), Expect = 5e-11
Identities = 79/399 (19%), Positives = 145/399 (36%), Gaps = 50/399 (12%)
Query: 18 ASESAKVPTAEPPGEVAVSESTREEQ------VPKPQAPAPQAPTASTATKPAPPSEDVP 71
+S K+ + + VS + +E++ VP P P Q+ A + P
Sbjct: 315 SSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAE-NPGAP 373
Query: 72 SAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQT 131
+PL + DV+ + ++W PP + Y +E C+ + EW+ P +
Sbjct: 374 GSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCP 433
Query: 132 VRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI------RENIEAP------------- 172
++ L G + RV A+S G+ P+ + + + R E P
Sbjct: 434 IQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITISTDA 493
Query: 173 ---KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT----G 225
+ +P + ++ E + + P+ +A T ++L+ + T
Sbjct: 494 FEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLT---YSLEKSVIGSGTWEAIS 550
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKP----------GPPSSIRL 275
+ + R A + RV + + D +P PP+ ++
Sbjct: 551 SESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQA 610
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLER-YHPTTCTISDLIIGN 334
+ +L W P +D ELLGY + T +W TV + T T+ L G
Sbjct: 611 FRDTQTSVSLTWDPVKD---PELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGK 667
Query: 335 SYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGF 373
Y F V S + G+ S+ T+ + Q + P GF
Sbjct: 668 EYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGF 706
Score = 56.6 bits (135), Expect = 5e-08
Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
Query: 378 FSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGN----PKYRALSE 433
+ P F PL H + L C+V+ASP P++ W KN I KYR +
Sbjct: 150 YGRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNN 209
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
G+ +LEIR+ + DS YT + N G+AS ++ V+
Sbjct: 210 YGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVR 248
Score = 56.6 bits (135), Expect = 5e-08
Identities = 55/207 (26%), Positives = 85/207 (41%), Gaps = 12/207 (5%)
Query: 208 WTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEK 266
W +G L S+R + D+ + L + + D G Y + V + +LV +
Sbjct: 306 WFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDA 365
Query: 267 -------PGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLER 319
PG P ++R LDV L W PP DT + Y +++ ++G+W E
Sbjct: 366 EAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEA 425
Query: 320 YHPT-TCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDF 378
T C I L+ G SY FRV + + G S + + EL + D AA+ K I D
Sbjct: 426 PGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKAS-ELVVMGDHD-AARRKTEIPFDL 483
Query: 379 SEAPSF-TQPLADHTSTPGYSTQLFCS 404
+ T D + P T + S
Sbjct: 484 GNKITISTDAFEDTVTIPSPPTNVHAS 510
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/71 (29%), Positives = 29/71 (40%)
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L C V P P+I W+KN + +YR T+ I K + DSG Y N
Sbjct: 1354 LTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKY 1413
Query: 461 GEASVDCRLEV 471
G + + V
Sbjct: 1414 GSETGQVTISV 1424
Score = 30.8 bits (68), Expect = 2.8
Identities = 26/109 (23%), Positives = 43/109 (39%), Gaps = 5/109 (4%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHA---LDSQRVSMRTG 225
IE + +V R L +T+ L G P P+ +W N LD R+ +R
Sbjct: 1329 IEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVR-- 1386
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIR 274
+ + I DSGRY + V+ + + I V + P ++
Sbjct: 1387 GTEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKELK 1435
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 78.2 bits (191), Expect = 2e-14
Identities = 92/431 (21%), Positives = 164/431 (38%), Gaps = 55/431 (12%)
Query: 55 PTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P+ T+ A VPSAP + + +SV V W+ P+ L GY ++ C G
Sbjct: 596 PSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKH--EEDLLGYYVDCCVAGT 653
Query: 115 SEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKI 174
+ W P + +P+ + V L G++++ RV AV++ G + I ++ +
Sbjct: 654 NLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ-----AAL 708
Query: 175 RVPRH-LRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMR-------TGD 226
VP H T + G ++ L PK G+ LD + V + +
Sbjct: 709 TVPSHPYGITLLNCDGHSMTLGWKV---PKFSGGSPILGYYLDKREVHHKNWHEVNSSPS 765
Query: 227 QDSILFIRSAQRSDSGRYELTVRV---------EDLEAKAVIDILVIEKPGPPSSIRLLD 277
+ +IL + ++ YE + D + + +PGP + +
Sbjct: 766 KPTILTVDGL--TEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCE 823
Query: 278 VWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCT----ISDLIIG 333
V + + W P +G++ + GY V ++ G+W TV + TT +SDL G
Sbjct: 824 VRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQ---TTTANRYLKVSDLQQG 880
Query: 334 NSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTS 393
+Y FRV + N G+ KP E EA T+ ++
Sbjct: 881 KTYVFRVRAVNANGV-------------------GKPSDTSEPVLVEARPGTKEISAGVD 921
Query: 394 TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYT 453
G F + + W K+ EI + +++ + L ++ P D G Y+
Sbjct: 922 EQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYS 981
Query: 454 CKAINVLGEAS 464
+ G +S
Sbjct: 982 VSVSDTDGVSS 992
Score = 70.1 bits (170), Expect = 4e-12
Identities = 72/302 (23%), Positives = 121/302 (40%), Gaps = 41/302 (13%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT- 128
VP P + ++S + V +SWEPP G+ L Y +E G+ W V+A+ + +
Sbjct: 510 VPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSP 568
Query: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKI--RV---------- 176
+ V +L G ++ RV + + G P+ + PI ++ P RV
Sbjct: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSV 628
Query: 177 ------PRH---LRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ 227
P+H L Y+ NL P KP + +G Q + R
Sbjct: 629 VVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYI-FRVKAV 687
Query: 228 DSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQW 287
+++ ++Q SD + + + V P P I LL+ G + L W
Sbjct: 688 NAVGMSENSQESDVIKVQAALTV----------------PSHPYGITLLNCDGHSMTLGW 731
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLC 346
P+ +G + +LGY + K + W V PT T+ L G+ Y F++ + NL
Sbjct: 732 KVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLA 791
Query: 347 GL 348
G+
Sbjct: 792 GI 793
Score = 61.2 bits (147), Expect = 2e-09
Identities = 91/434 (20%), Positives = 160/434 (36%), Gaps = 73/434 (16%)
Query: 62 KPAPPSEDV---------PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCRE 112
+P+ PSE P LT +V +S+ + W+ P G + GY ++ E
Sbjct: 795 EPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREE 854
Query: 113 GASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
A EW+ V+ V +L G ++ RV AV++ G G P+ +P+ +
Sbjct: 855 DAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTK 914
Query: 173 KIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQA---TWTHNGHAL-DSQRVSMRTGDQD 228
+I V E N+ + F + A TW + + D +R + T
Sbjct: 915 EISA----------GVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDH 964
Query: 229 SILFIRSAQRSDSGRYELTVR------------VEDLEAKAVIDILVIEKPGPPSSIRLL 276
S L++++ + D G Y ++V E+LE + + P S
Sbjct: 965 SKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAY 1024
Query: 277 DVWGCNAALQWTPPQDTGNTELLGYMVQ------------KADKKTGQWFTVLERY---H 321
+++ W + +++ K DK TG V++R+ +
Sbjct: 1025 EIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIEN 1084
Query: 322 PTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEA 381
T T+ + G + S +L + + E A Q+ + K +
Sbjct: 1085 EGTYTV-QIHDGKAKS----QSSLVLIGDAFKTVLEEAEFQRKEFLRK----------QG 1129
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKII-WMKNKM--EIQGNPKYRALSEQGVCT 438
P F + L T +L C V + K + W+K+ + E + P E+G+C
Sbjct: 1130 PHFAEYL-HWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL----ERGICE 1184
Query: 439 LEIRKPSPFDSGVY 452
L I K S D G Y
Sbjct: 1185 LLIPKLSKKDHGEY 1198
Score = 60.8 bits (146), Expect = 3e-09
Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 15/233 (6%)
Query: 186 RQVGETVNLQIPFQGKP-----KPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRS 239
R+ GETV L+ P +P+A W + L +S+ M G+ + L +
Sbjct: 289 RREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKD 348
Query: 240 DSGRYELTV----RVEDLEAKAVI---DILVIEKPGPPSSIRLLDVWGCNAALQWTPPQD 292
D G Y L + V D A + D LV PG P ++ D + W PP
Sbjct: 349 DEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNT 408
Query: 293 TGNTELLGYMVQKADKKTGQWFTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
T + ++GY V + + T W + ++ L G SY FRV + N G+S
Sbjct: 409 TTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRP 468
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCS 404
+ V+ +A + D+ +E + E + L PG T + S
Sbjct: 469 SRVSDAVAALDPLDLRRLQAVHLEGE-KEIAIYQDDLEGDAQVPGPPTGVHAS 520
Score = 60.1 bits (144), Expect = 4e-09
Identities = 28/105 (26%), Positives = 52/105 (49%)
Query: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
P AP+ L D + V V+W+PP + GY ++ C G + WV + P+ + +
Sbjct: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIR 175
V L G ++ RV AV+SAG P+ + + + ++ +++
Sbjct: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQ 487
Score = 56.6 bits (135), Expect = 5e-08
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 13/131 (9%)
Query: 242 GRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGY 301
G E+ + +DLE A + PGPP+ + ++ L W PP G L+ Y
Sbjct: 493 GEKEIAIYQDDLEGDAQV-------PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-Y 544
Query: 302 MVQKADKKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELA 359
++K+ +G W V + + DL+ G SY FRV S N GLS + +T +
Sbjct: 545 FIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT---S 601
Query: 360 HIQKADIAAKP 370
IQ D+ P
Sbjct: 602 PIQAQDVTVVP 612
Score = 50.1 bits (118), Expect = 4e-06
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 17/125 (13%)
Query: 33 VAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWE 92
V +SE+++E V K QA VPS P +TL + S+T+ W+
Sbjct: 690 VGMSENSQESDVIKVQAALT-----------------VPSHPYGITLLNCDGHSMTLGWK 732
Query: 93 PPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAG 152
P+ G + GY L+ W V++ P T TV L G + +++AV+ AG
Sbjct: 733 VPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAG 792
Query: 153 AGPPA 157
G P+
Sbjct: 793 IGEPS 797
Score = 45.8 bits (107), Expect = 8e-05
Identities = 33/101 (32%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 375 ERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI--QGNP-KYRAL 431
E S AP L HT S +L +V+ P P + W K+ I P KYR
Sbjct: 147 EERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIE 206
Query: 432 SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
S GV TLEI + D+ Y+ A N G+ S + + V+
Sbjct: 207 SNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVR 247
Score = 42.0 bits (97), Expect = 0.001
Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 392 TSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-VCTLEIRKPSPFDSG 450
T G + L C+V +P P++IW KN +IQ + + EQ ++ I+ + DSG
Sbjct: 1355 TIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSG 1414
Query: 451 VYTCKAINVLGEASVDCRLEV 471
Y+ N G +D + V
Sbjct: 1415 KYSINIKNKYGGEKIDVTVSV 1435
Score = 31.6 bits (70), Expect = 1.7
Identities = 16/63 (25%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSI-LFIRSAQRSDSGRYEL 246
G+T+NL G P P+ W N + S+ S++ + + I+ DSG+Y +
Sbjct: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418
Query: 247 TVR 249
++
Sbjct: 1419 NIK 1421
>gi|140560919 myomesin 1 isoform a [Homo sapiens]
Length = 1685
Score = 72.8 bits (177), Expect = 6e-13
Identities = 65/305 (21%), Positives = 109/305 (35%), Gaps = 71/305 (23%)
Query: 68 EDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127
E P+APL + + + + +SW+ P G + GY ++ C G W + P+
Sbjct: 507 EGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKF 566
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
+ V L G ++ RV AV+ G G P+ + +P+ + E ++
Sbjct: 567 ARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARL------------- 613
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
K +P A WT G+ +T
Sbjct: 614 -------------KSRPSAPWT--------------------------------GQIIVT 628
Query: 248 VRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKAD 307
E+ ++ ++ PGPP+ + + + L W PP G+ ++ Y V+K +
Sbjct: 629 ---EEEPSEGIV-------PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCE 677
Query: 308 KKTGQWFTVLER--YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
T W V + DL G SY FRV N G+ + T+ K D
Sbjct: 678 AGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLD 737
Query: 366 IAAKP 370
I P
Sbjct: 738 IPKAP 742
Score = 58.9 bits (141), Expect = 1e-08
Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 52 PQAP-TASTATKPAPPSED-VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLEL 109
P AP T PSE VP P L++ + + S V +SW+PP + G G+ Y +E
Sbjct: 617 PSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEK 675
Query: 110 CREGASEWVPVSAR-PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168
C G W V+ P+ + + +LA G + RV +SAG G P+ + + +
Sbjct: 676 CEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDK 735
Query: 169 IEAPK 173
++ PK
Sbjct: 736 LDIPK 740
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 22/204 (10%)
Query: 264 IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV--QKADKKTGQWFTVLE-RY 320
I PGPP S++ +V + LQW PP +G T + GY V ++A K QW + E
Sbjct: 1036 IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
Query: 321 HPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSE 380
+ L G SY FRV + N G+ KP +E
Sbjct: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGV-------------------GKPSDLAGPVVAE 1136
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
T+ + + G + F + +PK + W K+ + + +P+ S+ +
Sbjct: 1137 TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMT 1196
Query: 441 IRKPSPFDSGVYTCKAINVLGEAS 464
+ D G+Y+C + G AS
Sbjct: 1197 FKDLGMDDLGIYSCDVTDTDGIAS 1220
Score = 57.0 bits (136), Expect = 4e-08
Identities = 83/414 (20%), Positives = 159/414 (38%), Gaps = 56/414 (13%)
Query: 70 VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASE--WVPVSARPMMV 127
VP P L +V S+ + W+PP GR + GY ++L A E W ++ +
Sbjct: 1038 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
Query: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQ 187
VR L G ++ RV A++ AG G P+ ++ P + R + +
Sbjct: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPS----------DLAGPVVAETRPGTKEVVVN 1147
Query: 188 VGETVNLQIPFQ---GKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGR 243
V + + + F+ PK + +W+ + + DS R+ + + + + + D G
Sbjct: 1148 VDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGI 1207
Query: 244 YELTVR----------VEDLEAKAVIDILVIEK--PGPPSSIRLLDVWGCNAALQWTPPQ 291
Y V +++ E K ++ + K P S +++ W +
Sbjct: 1208 YSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAE 1267
Query: 292 DTGNTELLGYMVQK------------ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR 339
+ Y+ + D+ TG +E+ +Y+F+
Sbjct: 1268 KLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDED--------EGTYTFQ 1319
Query: 340 VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYST 399
+ ST V +QK + + + +I + + P F + L+ T +
Sbjct: 1320 LQDGKATNHSTVVLVGDVFKKLQK-EAEFQRQEWIRK---QGPHFVEYLSWEV-TGECNV 1374
Query: 400 QLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVY 452
L C V + I+W K++ EI + K+ + G+CTL I + S D+G+Y
Sbjct: 1375 LLKCKVANIKKETHIVWYKDEREISVDEKHD--FKDGICTLLITEFSKKDAGIY 1426
Score = 55.8 bits (133), Expect = 8e-08
Identities = 69/314 (21%), Positives = 125/314 (39%), Gaps = 21/314 (6%)
Query: 55 PTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGA 114
P+ +T D+P AP + + +SV VSWE E L GY +E G+
Sbjct: 723 PSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGS 780
Query: 115 SEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKI 174
+W P + P+ ++ T L G ++ RV AV++AG + + I + K
Sbjct: 781 GKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEV-------KA 833
Query: 175 RVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRT--GDQDSILF 232
+ + + + +G+ + T AL + + + ++
Sbjct: 834 AIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQ 893
Query: 233 IRSAQRSDSGRYELTVRVEDL--EAKAVIDILVIEKP-GPPS---SIRLLDVWGCNAALQ 286
++ S++ + ELT + + K+ D L + PPS I L+ + + L
Sbjct: 894 TEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLG 953
Query: 287 WTPPQDTGNTELLGYMV---QKADKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFS 342
W P G E+ GY V + D G+W ++ IS+L Y F+V +
Sbjct: 954 WKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAA 1013
Query: 343 ENLCGLSTSATVTK 356
N+ GL + V++
Sbjct: 1014 MNMAGLGAPSAVSE 1027
Score = 52.0 bits (123), Expect = 1e-06
Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 35 VSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPP 94
VSE+ +EE P PQ APQ + S K PS P +T + S+ + W+ P
Sbjct: 899 VSETVQEELTPPPQKAAPQGKSKSDPLK-KKTDRAPPSPPCDITCLESFRDSMVLGWKQP 957
Query: 95 ERLGRLGLQGYVL---ELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSA 151
+++G + GY + E+ +W + + + + NL + +V+A++ A
Sbjct: 958 DKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMA 1017
Query: 152 GAGPPAMLDQ 161
G G P+ + +
Sbjct: 1018 GLGAPSAVSE 1027
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/95 (34%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK--MEIQGNP-KYRALSEQGVC 437
AP F HT + +L CS+ P+P++ W KN+ + + NP KY S G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 438 TLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
TLEI D+ Y A+NV GE S + VK
Sbjct: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 50.8 bits (120), Expect = 3e-06
Identities = 41/175 (23%), Positives = 75/175 (42%), Gaps = 11/175 (6%)
Query: 203 KPQATWTHNGHALDSQR--VSMRTGDQDSILFIRSAQRSDSGRYELTVRV----EDLEAK 256
+P+ W NG L + ++ +G++ ++ F + D G Y + VR+ E A
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496
Query: 257 AVI---DILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW 313
+ D + P P ++ L+ + W P G + +LGY + K + T W
Sbjct: 497 VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
Query: 314 FTVLER-YHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIA 367
+ ++ LI G SY FRV + N G+ + V++ +A + A+ A
Sbjct: 557 SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKA 611
Score = 33.5 bits (75), Expect = 0.44
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Query: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTGD 226
E + RV L Q G+ +NL G P P+ +W N AL D + G
Sbjct: 1568 EKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAG- 1626
Query: 227 QDSILFIRSAQRSDSGRYELTVR 249
+ + I +DSG+Y L V+
Sbjct: 1627 RTAYFTINGVSTADSGKYGLVVK 1649
Score = 32.7 bits (73), Expect = 0.74
Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 1/81 (1%)
Query: 392 TSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-VCTLEIRKPSPFDSG 450
T G + L C+V P P++ W+KN+ + + E G I S DSG
Sbjct: 1583 TIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSG 1642
Query: 451 VYTCKAINVLGEASVDCRLEV 471
Y N G + D + V
Sbjct: 1643 KYGLVVKNKYGSETSDFTVSV 1663
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 70.1 bits (170), Expect = 4e-12
Identities = 100/378 (26%), Positives = 146/378 (38%), Gaps = 91/378 (24%)
Query: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAG--------PPAMLDQPIHIRENIEAPKIR 175
P+ ++Q+T+ + G LR+S V A AG P + D+ ++ ++ P +
Sbjct: 2162 PLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQ--VQVPPVL 2216
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRS 235
P + + G V L +G P P +W +G L SQ + +Q L + +
Sbjct: 2217 EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL-----EQGPSLQLEA 2271
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKP-----GPPSSIRLLDVWG----CNAALQ 286
DSG Y E EA+ + V+E P G P+ + L C+A Q
Sbjct: 2272 VGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDA--Q 2329
Query: 287 WTP-PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
TP P T + K GQ T LE NS + RV
Sbjct: 2330 GTPQPNITWH-------------KDGQALTRLEN--------------NSRATRVLRVRD 2362
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFS------------EAPSFTQPLADHTS 393
GL T +A P G IE+ F P F LA
Sbjct: 2363 AGLYTC--------------LAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLA---- 2404
Query: 394 TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYT 453
PG L CSV A P PKI W ++ + +Q + + E+G L+++ S DSG Y+
Sbjct: 2405 -PGQLV-LECSVEAEPAPKITWHRDGIVLQEDA-HTQFPERGRF-LQLQALSTADSGDYS 2460
Query: 454 CKAINVLGEASVDCRLEV 471
C A N G SV R+E+
Sbjct: 2461 CTARNAAGSTSVAFRVEI 2478
Score = 53.9 bits (128), Expect = 3e-07
Identities = 76/313 (24%), Positives = 121/313 (38%), Gaps = 49/313 (15%)
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
AP+IR R+ ++ + G+ V L G+P P W +G L +R
Sbjct: 2024 APRIRSSGVAREHHVLE-GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG 2082
Query: 230 ILFIRSAQRSDSGRYELTVR---VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
L ++ + SD+G Y ED V ++LV PP+ + D G
Sbjct: 2083 SLVLKGLRASDAGAYTCVAHNPAGEDARLHTV-NVLV-----PPTIKQGADGSG------ 2130
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL- 345
T G + V+ + W L+ P + L+ G+ ++ R+ L
Sbjct: 2131 -TLVSRPGELVTMVCPVRGSPPIHVSW---LKDGLPLPLSQRTLLHGSGHTLRISKVQLA 2186
Query: 346 -CGLSTSATVTKELAHIQKADIAAKPKGFIERDFS---EAPSFTQPLA---DHTSTPGYS 398
G+ T +AA P G +R+F+ + P +P+ D G
Sbjct: 2187 DAGIFTC--------------VAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSL 2232
Query: 399 TQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN 458
+L C R P P + WMK+ G P EQG +L++ DSG Y+C A++
Sbjct: 2233 VELPCEARGVPLPLVSWMKD-----GEPLLSQSLEQGP-SLQLEAVGAGDSGTYSCVAVS 2286
Query: 459 VLGEASVDCRLEV 471
GEA +L V
Sbjct: 2287 EAGEARRHFQLTV 2299
Score = 49.7 bits (117), Expect = 6e-06
Identities = 76/309 (24%), Positives = 119/309 (38%), Gaps = 40/309 (12%)
Query: 172 PKIRVPRHL-RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
P+I PR Q + Q G L+ GKP P TW +G + ++ + ++ +Q
Sbjct: 1065 PQIAGPREPPTQVSVVQDG-VATLECNATGKPPPTVTWERDGQPVGAE-LGLQLQNQGQS 1122
Query: 231 LFIRSAQRSDSGRYELTVR--VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
L + AQ + +GRY E K + +LV PP I LD A +
Sbjct: 1123 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV-----PPELIGDLDPLTNITAALHS 1177
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P T E +G +WF E P T L+ G G
Sbjct: 1178 PL--TLLCEAMGIPPPAI-----RWFRGEEPVSPGEDTY--LLAG-------------GW 1215
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEA----PSFTQPLADHTST--PGYSTQLF 402
T T+E + +A+ G R+FS PS + G + L
Sbjct: 1216 MLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLM 1275
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C+V P+PK+ W K+ + + +S GV L++ + + +G Y+C A N +GE
Sbjct: 1276 CNVTGHPQPKLTWFKDGRPLARGDAHH-ISPDGV-LLQVLQANLSSAGHYSCIAANAVGE 1333
Query: 463 ASVDCRLEV 471
+ +L V
Sbjct: 1334 KTKHFQLSV 1342
Score = 49.7 bits (117), Expect = 6e-06
Identities = 70/342 (20%), Positives = 124/342 (36%), Gaps = 41/342 (11%)
Query: 137 LGDKFLLRVSAVSSAGAGP-PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV----GET 191
L D +L+VS A A + + E + +++VP + + QV +
Sbjct: 1704 LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSS 1763
Query: 192 VNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
V+L P P+ TW + AL + V + G L + A+ SDSG Y
Sbjct: 1764 VSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT--LQLGRARLSDSGMYTCEALN 1821
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT-----GNTELLGYMVQK 305
+ ++ + V+ P + R PQD G+ +L
Sbjct: 1822 AAGRDQKLVQLSVLVPPAFRQAPR--------------GPQDAVLVRVGDKAVLSCETDA 1867
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ T W+ + L++ + L + + K L + ++
Sbjct: 1868 LPEPTVTWYKDGQ----------PLVLAQRTQALRGGQRL-EIQEAQVSDKGLYSCKVSN 1916
Query: 366 IAAKPKGFIERDFSEAPSFTQPLADHTS-TPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
+A + P+F P + S G L C V P P + W+K++M ++
Sbjct: 1917 VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVES 1976
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVD 466
+ + +S G L++ + P +G YTC A N EA D
Sbjct: 1977 SAVHGVVSRGG--RLQLSRLQPAQAGTYTCVAENTQAEARKD 2016
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
QL C R P P I W K+ + + K + +G L++ + D+GVYTCKA N
Sbjct: 330 QLLCEARGVPTPNITWFKDGALLPTSTK--VVYTRGGRQLQLGRAQSSDAGVYTCKASNA 387
Query: 460 LGEASVDCRLEV 471
+G A RL+V
Sbjct: 388 VGAAEKATRLDV 399
Score = 47.8 bits (112), Expect = 2e-05
Identities = 70/282 (24%), Positives = 113/282 (40%), Gaps = 40/282 (14%)
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
TV+LQ P G P P +W NG S ++ + +L + +A+ +D+ Y + V
Sbjct: 1671 TVSLQCPALGNPVPTISWLQNGLPF-SPSPRLQVLEDGQVLQVSTAEVADAASY---MCV 1726
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP--PQDT---GNTELLGYMVQK 305
+ +A + + + PP I LD+ A L + P D N E+ Y +
Sbjct: 1727 AENQAGSAEKLFTLRVQVPP-RIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 1785
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
A + F + P T T+ +G + LS S T E +
Sbjct: 1786 ALSLGEEVFLL-----PGTHTLQ---LGRA-----------RLSDSGMYTCE-----ALN 1821
Query: 366 IAAKPKGFIERDFSEAPSFTQ----PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
A + + ++ P+F Q P G L C A P+P + W K+
Sbjct: 1822 AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQP 1881
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ + +AL +G LEI++ D G+Y+CK NV GEA
Sbjct: 1882 LVLAQRTQAL--RGGQRLEIQEAQVSDKGLYSCKVSNVAGEA 1921
Score = 47.4 bits (111), Expect = 3e-05
Identities = 61/271 (22%), Positives = 109/271 (40%), Gaps = 41/271 (15%)
Query: 199 QGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
+G P+P TW +G + T L +++ + D+G Y T A+
Sbjct: 2871 RGSPEPNITWDKDGQPVSGAEGKF-TIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR 2929
Query: 259 IDILVIEKP-----GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW 313
+ + ++ P S+RL D A + +P T +G+ V G
Sbjct: 2930 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSP------TPRIGWTVNDRPVTEG-- 2981
Query: 314 FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGF 373
V E+ +T + + +S ++ ++EN G + + + H+++A +
Sbjct: 2982 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVS----FVHVKEAPVLQ----- 3030
Query: 374 IERDFSEAPSF-TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
EA S+ +P+ G S QL C VR P P I W+K+ + ++G+ L
Sbjct: 3031 -----GEAFSYLVEPV-------GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 3078
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+L I + D+G Y C A N +G A
Sbjct: 3079 NG---SLTIHRTERDDAGRYQCLAENEMGVA 3106
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/94 (35%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 381 APSFTQPLAD-HTST--PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
AP F PL + HT T G+ T L C R P PKI W K+ + G
Sbjct: 970 APVF--PLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGR 1027
Query: 438 TLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
L + + G YTC+ NV+G +S D +LEV
Sbjct: 1028 LLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEV 1061
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P L D ++T G L C R SP+P I W K+ + G + G L +
Sbjct: 2847 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLV 2904
Query: 442 RKPSPFDSGVYTCKAINVLGEA 463
+ D+G YTC A N +G A
Sbjct: 2905 KNLEGQDAGTYTCTAENAVGRA 2926
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 392 TSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGV 451
T T L C A P P I WMK+ + + + L G L+I D+G
Sbjct: 1361 TVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKEDAGQ 1418
Query: 452 YTCKAINVLGEASVDCRLEV 471
YTC N LGEA + +EV
Sbjct: 1419 YTCVVTNELGEAVKNYHVEV 1438
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 24/169 (14%)
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKA 364
K + W V I + ++ S+R + N+ G + EL + +
Sbjct: 730 KGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAG-------STELRYGLRV 782
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK--NKMEI 422
++ + + PS P+ +T +L C+ +P P ++W+K N +
Sbjct: 783 NVPPR--------ITLPPSLPGPVLVNTPV-----RLTCNATGAPSPTLMWLKDGNPVSP 829
Query: 423 QGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
G P + V TL + S DSG Y+C A++ +GE D L+V
Sbjct: 830 AGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVLQV 876
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 403 CSVRASPKPKIIWMKNKME--IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
C +PKP++ W K + G P L E +L + SP DSG Y C+A N +
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG---SLFLASVSPADSGDYECQATNEV 80
Query: 461 GEASVDCRLEV 471
G S +L V
Sbjct: 81 GSTSRRAKLVV 91
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 6/92 (6%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQ-GVCTLE 440
P FT D + G L C+ R SP P+I W N P +SEQ G TL+
Sbjct: 2938 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVND-----RPVTEGVSEQDGGSTLQ 2992
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
S DSG Y C A N +G + VK
Sbjct: 2993 RAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 3024
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 393 STPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVY 452
S PG + C VR SP + W+K+ + + R L TL I K D+G++
Sbjct: 2134 SRPGELVTMVCPVRGSPPIHVSWLKDGLPLP--LSQRTLLHGSGHTLRISKVQLADAGIF 2191
Query: 453 TCKAINVLGEASVDCRLEVK 472
TC A + G A + L+V+
Sbjct: 2192 TCVAASPAGVADRNFTLQVQ 2211
Score = 40.0 bits (92), Expect = 0.005
Identities = 61/275 (22%), Positives = 103/275 (37%), Gaps = 28/275 (10%)
Query: 202 PKPQATWTHNGHALDSQR-VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEA--KAV 258
P P TW +G ++ R + + G L I +AQ+ D+G+Y V E EA
Sbjct: 1378 PSPNITWMKDGAPFEASRNIQLLPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYH 1435
Query: 259 IDILV---IEKPGPPSSIRLLDV-WGCNAAL-----QWTPPQDTGNTELLGYMVQKADKK 309
+++L+ I K P + + +V N+ L W P T G V + +
Sbjct: 1436 VEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRL 1495
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA--TVTKELAHIQKADIA 367
L + PT + +S + + N+ G + + QK
Sbjct: 1496 QVLGEGRLLQIQPTQ-------VSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDF 1548
Query: 368 AKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPK 427
+ + R+ T+ + P Y L+C A P P + W + + +
Sbjct: 1549 SAAFEILSREEEARGGVTEYREIVENNPAY---LYCDTNAIPPPDLTWYREDQPLSAGDE 1605
Query: 428 YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
L QG L+I ++G Y+CKA N +GE
Sbjct: 1606 VSVL--QGGRVLQIPLVRAENAGRYSCKASNEVGE 1638
Score = 40.0 bits (92), Expect = 0.005
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 3/92 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP F D T G L C P P I W++ ++ + + R L + +L
Sbjct: 3117 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---SLW 3173
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ D+G Y C A N+LG A+ L V+
Sbjct: 3174 LENVETGDAGTYDCVAHNLLGSATARAFLVVR 3205
Score = 39.3 bits (90), Expect = 0.008
Identities = 65/310 (20%), Positives = 110/310 (35%), Gaps = 59/310 (19%)
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDS 241
Q + G V LQ G P PQ WT + + ++ + +L I + D
Sbjct: 225 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE 284
Query: 242 GRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL-G 300
GRY+ + + V PP+ +WG N +TG ++
Sbjct: 285 GRYQCVAFSPAGQQARDFQLRV---HAPPT------IWGSN---------ETGEVAVMED 326
Query: 301 YMVQKADKKTG------QWFTVLERYHPTTCTI-----SDLIIGNSYS-----FRVFSEN 344
++VQ + G WF +T + L +G + S + + N
Sbjct: 327 HLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASN 386
Query: 345 LCGLSTSATVTKELAHIQKADIAAKP--KGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
G + AT + D+ P +G R + +P+A L
Sbjct: 387 AVGAAEKAT---------RLDVYVPPTIEGAGGRPYVVKAVAGRPVA-----------LE 426
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C R P P + W + + + + R ++ V LE P SG+Y+C A + GE
Sbjct: 427 CVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLE--SPGEASSGLYSCVASSPAGE 484
Query: 463 ASVDCRLEVK 472
A + +EV+
Sbjct: 485 AVLQYSVEVQ 494
Score = 39.3 bits (90), Expect = 0.008
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 398 STQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
S L C A P P + W K+ ++ P +++ + L++ + +D+G YTC+A+
Sbjct: 896 SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEAL 953
Query: 458 NVLGEASVDCRLEV 471
N G + L V
Sbjct: 954 NQAGRSEKHYNLNV 967
Score = 39.3 bits (90), Expect = 0.008
Identities = 72/342 (21%), Positives = 119/342 (34%), Gaps = 48/342 (14%)
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
+ R L + D L A S AGA +++ +R P I PR R G
Sbjct: 2353 RATRVLRVRDAGLYTCLAESPAGA-----IEKSFRVRVQAP-PNIVGPRGPRFVVGLAPG 2406
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ V L+ + +P P+ TW +G L + ++ L +++ +DSG Y T R
Sbjct: 2407 QLV-LECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRFLQLQALSTADSGDYSCTAR 2464
Query: 250 ----VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
+ + I + + GPP+ N ++ T LL
Sbjct: 2465 NAAGSTSVAFRVEIHTVPTIRSGPPA---------VNVSVN--------QTALLPCQADG 2507
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN----LCGLSTSATVTKELAHI 361
W P + L G+ V +++ LC S SA ++ +
Sbjct: 2508 VPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL 2567
Query: 362 QKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
+ E P+ ++ T T L C SPKP ++W K+ +
Sbjct: 2568 RVL---------------EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQK 2612
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ + A L + P P DS + C N +GEA
Sbjct: 2613 LDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEA 2654
Score = 38.1 bits (87), Expect = 0.018
Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ D T T L C P P + W K ++ +S G LEI
Sbjct: 2666 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGA--LEI 2723
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
+ P +G YTC A N G A L V+AS
Sbjct: 2724 GQALPIHAGRYTCSARNSAGVAHKHVFLTVQAS 2756
Score = 37.0 bits (84), Expect = 0.039
Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L C A P P I W K+ + + + + L E + L+I+ DSG Y C A NV
Sbjct: 1468 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVSDSGRYLCVATNVA 1525
Query: 461 GEASVD 466
GE D
Sbjct: 1526 GEDDQD 1531
Score = 36.6 bits (83), Expect = 0.051
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 9/80 (11%)
Query: 394 TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYT 453
TPG +L C + +P+P I W K+ + + + L +R D+G+YT
Sbjct: 2317 TPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN----NSRATRVLRVR-----DAGLYT 2367
Query: 454 CKAINVLGEASVDCRLEVKA 473
C A + G R+ V+A
Sbjct: 2368 CLAESPAGAIEKSFRVRVQA 2387
Score = 36.2 bits (82), Expect = 0.067
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
+ VG ++ L +G P P W +G L +R Q+ L I +R D+GRY
Sbjct: 3038 VEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSH--LRHQLQNGSLTIHRTERDDAGRY 3095
Query: 245 ELTVRVEDLEAKAVIDILVIE 265
+ E AK V+ ILV++
Sbjct: 3096 QCLAENEMGVAKKVV-ILVLQ 3115
Score = 35.8 bits (81), Expect = 0.088
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 385 TQPLADHTSTPGYST-QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
T+ L + + ST L C +P P I W++N + +P+ + L + V L++
Sbjct: 1657 TEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV--LQVST 1714
Query: 444 PSPFDSGVYTCKAINVLGEA 463
D+ Y C A N G A
Sbjct: 1715 AEVADAASYMCVAENQAGSA 1734
Score = 34.7 bits (78), Expect = 0.20
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 10/88 (11%)
Query: 388 LADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR----ALSEQGVCTLEIRK 443
L T+ G +L C SP P I W++N G P ++ QG TL I
Sbjct: 505 LGQVTTIVGQPLELPCQASGSPVPTIQWLQN-----GRPAEELAGVQVASQGT-TLHIDH 558
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEV 471
SG++ C+A N G A + + V
Sbjct: 559 VELDHSGLFACQATNEAGTAGAEVEVSV 586
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G +L C P P++ W K++ + + + E G L I D G Y C
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGRYQCV 290
Query: 456 AINVLGEASVDCRLEVKA 473
A + G+ + D +L V A
Sbjct: 291 AFSPAGQQARDFQLRVHA 308
Score = 33.9 bits (76), Expect = 0.33
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C P+P I W K + + + L L I SP D+G Y C A N G
Sbjct: 2778 CEASGIPRPTITWQKEGLNVATGVSTQVLPGG---QLRIAHASPEDAGNYLCIAKNSAGS 2834
Query: 463 ASVDCRLEVK 472
A RL V+
Sbjct: 2835 AMGKTRLVVQ 2844
Score = 32.3 bits (72), Expect = 0.97
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 407 ASPKPKII--WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
A PKP ++ W + + G P ++ L+I K D G+YTC A N+ GE+
Sbjct: 626 AHPKPPLVEGWC-SPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESK 684
Query: 465 VDCRLEV 471
+ L+V
Sbjct: 685 REVALKV 691
Score = 32.0 bits (71), Expect = 1.3
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 6/110 (5%)
Query: 138 GDKFLLRVSAVSSAGAGP-----PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETV 192
G +L+ S AGA PA D +H + P I+ T + + GE V
Sbjct: 2081 GGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELV 2140
Query: 193 NLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
+ P +G P +W +G L + ++ G + L I Q +D+G
Sbjct: 2141 TMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT-LRISKVQLADAG 2189
Score = 30.0 bits (66), Expect = 4.8
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 146 SAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQ 205
S V+S+ AG A+L + ++ P++ V L Q VG+ + L G P P
Sbjct: 475 SCVASSPAGE-AVLQYSVEVQV---PPQLLVAEGLGQV-TTIVGQPLELPCQASGSPVPT 529
Query: 206 ATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILV 263
W NG + + ++ Q + L I + SG + E A A +++ V
Sbjct: 530 IQWLQNGRPAE-ELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 586
Score = 30.0 bits (66), Expect = 4.8
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRV-SMR 223
+R N+ P+I +P L + V V L G P P W +G+ + ++
Sbjct: 780 LRVNVP-PRITLPPSLPGPVL--VNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQ 836
Query: 224 TGDQDSILFIRSAQRSDSGRY 244
+L + SA+ SDSGRY
Sbjct: 837 VFPGGRVLTLASARASDSGRY 857
Score = 29.6 bits (65), Expect = 6.3
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 171 APKIRVPRHLRQTYIRQV---GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ 227
A K+ VP ++ + + +V L+ G P P +W GH S + +
Sbjct: 688 ALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSW-FKGHQPVSSWMGVTVSVD 746
Query: 228 DSILFIRSAQRSDSGRY 244
+L I AQ SD+G Y
Sbjct: 747 GRVLRIEQAQLSDAGSY 763
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 70.1 bits (170), Expect = 4e-12
Identities = 100/378 (26%), Positives = 146/378 (38%), Gaps = 91/378 (24%)
Query: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAG--------PPAMLDQPIHIRENIEAPKIR 175
P+ ++Q+T+ + G LR+S V A AG P + D+ ++ ++ P +
Sbjct: 3353 PLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQ--VQVPPVL 3407
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRS 235
P + + G V L +G P P +W +G L SQ + +Q L + +
Sbjct: 3408 EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL-----EQGPSLQLEA 3462
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKP-----GPPSSIRLLDVWG----CNAALQ 286
DSG Y E EA+ + V+E P G P+ + L C+A Q
Sbjct: 3463 VGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDA--Q 3520
Query: 287 WTP-PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
TP P T + K GQ T LE NS + RV
Sbjct: 3521 GTPQPNITWH-------------KDGQALTRLEN--------------NSRATRVLRVRD 3553
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFS------------EAPSFTQPLADHTS 393
GL T +A P G IE+ F P F LA
Sbjct: 3554 AGLYTC--------------LAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLA---- 3595
Query: 394 TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYT 453
PG L CSV A P PKI W ++ + +Q + + E+G L+++ S DSG Y+
Sbjct: 3596 -PGQLV-LECSVEAEPAPKITWHRDGIVLQEDA-HTQFPERGRF-LQLQALSTADSGDYS 3651
Query: 454 CKAINVLGEASVDCRLEV 471
C A N G SV R+E+
Sbjct: 3652 CTARNAAGSTSVAFRVEI 3669
Score = 53.9 bits (128), Expect = 3e-07
Identities = 76/313 (24%), Positives = 121/313 (38%), Gaps = 49/313 (15%)
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
AP+IR R+ ++ + G+ V L G+P P W +G L +R
Sbjct: 3215 APRIRSSGVAREHHVLE-GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG 3273
Query: 230 ILFIRSAQRSDSGRYELTVR---VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
L ++ + SD+G Y ED V ++LV PP+ + D G
Sbjct: 3274 SLVLKGLRASDAGAYTCVAHNPAGEDARLHTV-NVLV-----PPTIKQGADGSG------ 3321
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL- 345
T G + V+ + W L+ P + L+ G+ ++ R+ L
Sbjct: 3322 -TLVSRPGELVTMVCPVRGSPPIHVSW---LKDGLPLPLSQRTLLHGSGHTLRISKVQLA 3377
Query: 346 -CGLSTSATVTKELAHIQKADIAAKPKGFIERDFS---EAPSFTQPLA---DHTSTPGYS 398
G+ T +AA P G +R+F+ + P +P+ D G
Sbjct: 3378 DAGIFTC--------------VAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSL 3423
Query: 399 TQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN 458
+L C R P P + WMK+ G P EQG +L++ DSG Y+C A++
Sbjct: 3424 VELPCEARGVPLPLVSWMKD-----GEPLLSQSLEQGP-SLQLEAVGAGDSGTYSCVAVS 3477
Query: 459 VLGEASVDCRLEV 471
GEA +L V
Sbjct: 3478 EAGEARRHFQLTV 3490
Score = 50.1 bits (118), Expect = 4e-06
Identities = 36/114 (31%), Positives = 48/114 (42%), Gaps = 6/114 (5%)
Query: 366 IAAKPKGFIERDFS---EAPSFTQPLADHTST-PGYSTQLFCSVRASPKPKIIWMKNKME 421
+A G RD + P P A H T G L C P P I W K
Sbjct: 956 VATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNA 1015
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ + +S++G TL I +PS D+G Y C A N +G +S + RL V A
Sbjct: 1016 LTSRGPHYNVSKEG--TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLA 1067
Score = 49.7 bits (117), Expect = 6e-06
Identities = 76/309 (24%), Positives = 119/309 (38%), Gaps = 40/309 (12%)
Query: 172 PKIRVPRHL-RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
P+I PR Q + Q G L+ GKP P TW +G + ++ + ++ +Q
Sbjct: 2256 PQIAGPREPPTQVSVVQDG-VATLECNATGKPPPTVTWERDGQPVGAE-LGLQLQNQGQS 2313
Query: 231 LFIRSAQRSDSGRYELTVR--VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
L + AQ + +GRY E K + +LV PP I LD A +
Sbjct: 2314 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV-----PPELIGDLDPLTNITAALHS 2368
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P T E +G +WF E P T L+ G G
Sbjct: 2369 PL--TLLCEAMGIPPPAI-----RWFRGEEPVSPGEDTY--LLAG-------------GW 2406
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEA----PSFTQPLADHTST--PGYSTQLF 402
T T+E + +A+ G R+FS PS + G + L
Sbjct: 2407 MLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLM 2466
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C+V P+PK+ W K+ + + +S GV L++ + + +G Y+C A N +GE
Sbjct: 2467 CNVTGHPQPKLTWFKDGRPLARGDAHH-ISPDGV-LLQVLQANLSSAGHYSCIAANAVGE 2524
Query: 463 ASVDCRLEV 471
+ +L V
Sbjct: 2525 KTKHFQLSV 2533
Score = 49.7 bits (117), Expect = 6e-06
Identities = 70/342 (20%), Positives = 124/342 (36%), Gaps = 41/342 (11%)
Query: 137 LGDKFLLRVSAVSSAGAGP-PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV----GET 191
L D +L+VS A A + + E + +++VP + + QV +
Sbjct: 2895 LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSS 2954
Query: 192 VNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
V+L P P+ TW + AL + V + G L + A+ SDSG Y
Sbjct: 2955 VSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT--LQLGRARLSDSGMYTCEALN 3012
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT-----GNTELLGYMVQK 305
+ ++ + V+ P + R PQD G+ +L
Sbjct: 3013 AAGRDQKLVQLSVLVPPAFRQAPR--------------GPQDAVLVRVGDKAVLSCETDA 3058
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ T W+ + L++ + L + + K L + ++
Sbjct: 3059 LPEPTVTWYKDGQ----------PLVLAQRTQALRGGQRL-EIQEAQVSDKGLYSCKVSN 3107
Query: 366 IAAKPKGFIERDFSEAPSFTQPLADHTS-TPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
+A + P+F P + S G L C V P P + W+K++M ++
Sbjct: 3108 VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVES 3167
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVD 466
+ + +S G L++ + P +G YTC A N EA D
Sbjct: 3168 SAVHGVVSRGG--RLQLSRLQPAQAGTYTCVAENTQAEARKD 3207
Score = 49.3 bits (116), Expect = 8e-06
Identities = 83/339 (24%), Positives = 127/339 (37%), Gaps = 56/339 (16%)
Query: 174 IRVPRHLRQT---YIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
++VP + T +I G +L G P P TWT +AL S+ + ++
Sbjct: 972 VQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTL 1031
Query: 231 LFIRSAQRSDSGRYELT----VRVEDLEAKAVIDILVIEKPG-------PPSSIRLLDV- 278
L I D+G Y T V E + ++ L + K P S+RL V
Sbjct: 1032 L-IAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQ 1090
Query: 279 ------WGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLII 332
+ C A+ P + +LG V + + VL ++ +
Sbjct: 1091 VGDSGHYECTAS---NPAGSASHRYVLGVQVPPQVQPGPRVLKVLVG---EALDLNCVAE 1144
Query: 333 GNSYSFRVFSEN---LCGLSTSATVTKELAHIQKADI------AAKPKGF----IERDFS 379
GN +S++ L G +V A I+ +D A+ G +E
Sbjct: 1145 GNPEPQLSWSKDGVVLQGRGPQGSV--HFAAIRTSDAGRYRCEASNSAGVDAWEVELRVL 1202
Query: 380 EAPSFTQPLADHTS-----TPGYSTQLFCSVRASPKPKIIWMKNKME--IQGNPKYRALS 432
E P + AD TS G + L C R +PKP++ W K + G P L
Sbjct: 1203 EPPHWG---ADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLE 1259
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
E +L + SP DSG Y C+A N +G S +L V
Sbjct: 1260 EG---SLFLASVSPADSGDYECQATNEVGSTSRRAKLVV 1295
Score = 49.3 bits (116), Expect = 8e-06
Identities = 79/308 (25%), Positives = 127/308 (41%), Gaps = 61/308 (19%)
Query: 188 VGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
VGE ++L +G P+PQ +W+ +G L + G Q S+ F + + SD+GRY
Sbjct: 1133 VGEALDLNCVAEGNPEPQLSWSKDGVVLQGR------GPQGSVHFA-AIRTSDAGRY--- 1182
Query: 248 VRVEDLEAKAV----IDILVIEKP--GPPSSIRLLD-VWGCNAALQWTPPQDTGNTELLG 300
R E + V +++ V+E P G + LL+ V G NA+L P + T ++
Sbjct: 1183 -RCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLP-CPARGTPKPQVTW 1240
Query: 301 YMVQKADKKTGQ-WFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELA 359
++ GQ VLE ++S +S + + N G STS
Sbjct: 1241 RKGPSSEPLHGQPGVAVLEEGSLFLASVSP---ADSGDYECQATNEVG-STS-------- 1288
Query: 360 HIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK 419
++A + I D +A + + G S L C P P+I+W+K+
Sbjct: 1289 --RRAKLVVYVPPSIREDGRKA--------NVSGMAGQSLTLECDANGFPVPEIVWLKD- 1337
Query: 420 MEIQGNP----------------KYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
++ G P +R L E +L + DSG+Y+C+A N G A
Sbjct: 1338 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ--SLHFPRIQEGDSGLYSCRAENQAGTA 1395
Query: 464 SVDCRLEV 471
D L V
Sbjct: 1396 QRDFHLLV 1403
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 9/96 (9%)
Query: 378 FSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
+++ PS + A G L C P P++IW + +E+ L+ +G
Sbjct: 694 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEM-------ILAPEGSS 746
Query: 438 TLEIRKPSPF--DSGVYTCKAINVLGEASVDCRLEV 471
+ ++R P+ D+G YTC+A+N LG+AS + +L V
Sbjct: 747 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
QL C R P P I W K+ + + K + +G L++ + D+GVYTCKA N
Sbjct: 1521 QLLCEARGVPTPNITWFKDGALLPTSTK--VVYTRGGRQLQLGRAQSSDAGVYTCKASNA 1578
Query: 460 LGEASVDCRLEV 471
+G A RL+V
Sbjct: 1579 VGAAEKATRLDV 1590
Score = 47.8 bits (112), Expect = 2e-05
Identities = 70/282 (24%), Positives = 113/282 (40%), Gaps = 40/282 (14%)
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
TV+LQ P G P P +W NG S ++ + +L + +A+ +D+ Y + V
Sbjct: 2862 TVSLQCPALGNPVPTISWLQNGLPF-SPSPRLQVLEDGQVLQVSTAEVADAASY---MCV 2917
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP--PQDT---GNTELLGYMVQK 305
+ +A + + + PP I LD+ A L + P D N E+ Y +
Sbjct: 2918 AENQAGSAEKLFTLRVQVPP-RIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 2976
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
A + F + P T T+ +G + LS S T E +
Sbjct: 2977 ALSLGEEVFLL-----PGTHTLQ---LGRA-----------RLSDSGMYTCE-----ALN 3012
Query: 366 IAAKPKGFIERDFSEAPSFTQ----PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
A + + ++ P+F Q P G L C A P+P + W K+
Sbjct: 3013 AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQP 3072
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ + +AL +G LEI++ D G+Y+CK NV GEA
Sbjct: 3073 LVLAQRTQAL--RGGQRLEIQEAQVSDKGLYSCKVSNVAGEA 3112
Score = 47.4 bits (111), Expect = 3e-05
Identities = 61/271 (22%), Positives = 109/271 (40%), Gaps = 41/271 (15%)
Query: 199 QGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
+G P+P TW +G + T L +++ + D+G Y T A+
Sbjct: 4062 RGSPEPNITWDKDGQPVSGAEGKF-TIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR 4120
Query: 259 IDILVIEKP-----GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW 313
+ + ++ P S+RL D A + +P T +G+ V G
Sbjct: 4121 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSP------TPRIGWTVNDRPVTEG-- 4172
Query: 314 FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGF 373
V E+ +T + + +S ++ ++EN G + + + H+++A +
Sbjct: 4173 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVS----FVHVKEAPVLQ----- 4221
Query: 374 IERDFSEAPSF-TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
EA S+ +P+ G S QL C VR P P I W+K+ + ++G+ L
Sbjct: 4222 -----GEAFSYLVEPV-------GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 4269
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+L I + D+G Y C A N +G A
Sbjct: 4270 NG---SLTIHRTERDDAGRYQCLAENEMGVA 4297
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/132 (30%), Positives = 56/132 (42%), Gaps = 18/132 (13%)
Query: 356 KELAHIQKADI---------AAKPKGFIERDFS----EAPSFTQPLAD-HTST--PGYST 399
K L + +AD+ A G E+ ++ AP F PL + HT T G+ T
Sbjct: 2123 KALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVF--PLRESHTLTVREGHPT 2180
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
L C R P PKI W K+ + G L + + G YTC+ NV
Sbjct: 2181 SLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNV 2240
Query: 460 LGEASVDCRLEV 471
+G +S D +LEV
Sbjct: 2241 VGNSSQDLQLEV 2252
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P L D ++T G L C R SP+P I W K+ + G + G L +
Sbjct: 4038 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLV 4095
Query: 442 RKPSPFDSGVYTCKAINVLGEA 463
+ D+G YTC A N +G A
Sbjct: 4096 KNLEGQDAGTYTCTAENAVGRA 4117
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 392 TSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGV 451
T T L C A P P I WMK+ + + + L G L+I D+G
Sbjct: 2552 TVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKEDAGQ 2609
Query: 452 YTCKAINVLGEASVDCRLEV 471
YTC N LGEA + +EV
Sbjct: 2610 YTCVVTNELGEAVKNYHVEV 2629
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 24/169 (14%)
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKA 364
K + W V I + ++ S+R + N+ G + EL + +
Sbjct: 1921 KGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAG-------STELRYGLRV 1973
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK--NKMEI 422
++ + + PS P+ +T +L C+ +P P ++W+K N +
Sbjct: 1974 NVPPR--------ITLPPSLPGPVLVNTPV-----RLTCNATGAPSPTLMWLKDGNPVSP 2020
Query: 423 QGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
G P + V TL + S DSG Y+C A++ +GE D L+V
Sbjct: 2021 AGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVLQV 2067
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 6/92 (6%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQ-GVCTLE 440
P FT D + G L C+ R SP P+I W N P +SEQ G TL+
Sbjct: 4129 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVND-----RPVTEGVSEQDGGSTLQ 4183
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
S DSG Y C A N +G + VK
Sbjct: 4184 RAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 4215
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
EAP + + + G ++ CS P P I W + +Q + + + QG TL
Sbjct: 606 EAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIH-VDAQG--TL 662
Query: 440 EIRKPSPFDSGVYTCKAINVLG 461
I+ +P D+G Y+C+A N +G
Sbjct: 663 IIQGVAPEDAGNYSCQATNEVG 684
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 393 STPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVY 452
S PG + C VR SP + W+K+ + + R L TL I K D+G++
Sbjct: 3325 SRPGELVTMVCPVRGSPPIHVSWLKDGLPLP--LSQRTLLHGSGHTLRISKVQLADAGIF 3382
Query: 453 TCKAINVLGEASVDCRLEVK 472
TC A + G A + L+V+
Sbjct: 3383 TCVAASPAGVADRNFTLQVQ 3402
Score = 40.0 bits (92), Expect = 0.005
Identities = 61/275 (22%), Positives = 103/275 (37%), Gaps = 28/275 (10%)
Query: 202 PKPQATWTHNGHALDSQR-VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEA--KAV 258
P P TW +G ++ R + + G L I +AQ+ D+G+Y V E EA
Sbjct: 2569 PSPNITWMKDGAPFEASRNIQLLPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYH 2626
Query: 259 IDILV---IEKPGPPSSIRLLDV-WGCNAAL-----QWTPPQDTGNTELLGYMVQKADKK 309
+++L+ I K P + + +V N+ L W P T G V + +
Sbjct: 2627 VEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRL 2686
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA--TVTKELAHIQKADIA 367
L + PT + +S + + N+ G + + QK
Sbjct: 2687 QVLGEGRLLQIQPTQ-------VSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDF 2739
Query: 368 AKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPK 427
+ + R+ T+ + P Y L+C A P P + W + + +
Sbjct: 2740 SAAFEILSREEEARGGVTEYREIVENNPAY---LYCDTNAIPPPDLTWYREDQPLSAGDE 2796
Query: 428 YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
L QG L+I ++G Y+CKA N +GE
Sbjct: 2797 VSVL--QGGRVLQIPLVRAENAGRYSCKASNEVGE 2829
Score = 40.0 bits (92), Expect = 0.005
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 3/92 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP F D T G L C P P I W++ ++ + + R L + +L
Sbjct: 4308 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---SLW 4364
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ D+G Y C A N+LG A+ L V+
Sbjct: 4365 LENVETGDAGTYDCVAHNLLGSATARAFLVVR 4396
Score = 39.3 bits (90), Expect = 0.008
Identities = 65/310 (20%), Positives = 110/310 (35%), Gaps = 59/310 (19%)
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDS 241
Q + G V LQ G P PQ WT + + ++ + +L I + D
Sbjct: 1416 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE 1475
Query: 242 GRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL-G 300
GRY+ + + V PP+ +WG N +TG ++
Sbjct: 1476 GRYQCVAFSPAGQQARDFQLRV---HAPPT------IWGSN---------ETGEVAVMED 1517
Query: 301 YMVQKADKKTG------QWFTVLERYHPTTCTI-----SDLIIGNSYS-----FRVFSEN 344
++VQ + G WF +T + L +G + S + + N
Sbjct: 1518 HLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASN 1577
Query: 345 LCGLSTSATVTKELAHIQKADIAAKP--KGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
G + AT + D+ P +G R + +P+A L
Sbjct: 1578 AVGAAEKAT---------RLDVYVPPTIEGAGGRPYVVKAVAGRPVA-----------LE 1617
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C R P P + W + + + + R ++ V LE P SG+Y+C A + GE
Sbjct: 1618 CVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLE--SPGEASSGLYSCVASSPAGE 1675
Query: 463 ASVDCRLEVK 472
A + +EV+
Sbjct: 1676 AVLQYSVEVQ 1685
Score = 39.3 bits (90), Expect = 0.008
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 398 STQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
S L C A P P + W K+ ++ P +++ + L++ + +D+G YTC+A+
Sbjct: 2087 SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEAL 2144
Query: 458 NVLGEASVDCRLEV 471
N G + L V
Sbjct: 2145 NQAGHSEKHYNLNV 2158
Score = 39.3 bits (90), Expect = 0.008
Identities = 72/342 (21%), Positives = 119/342 (34%), Gaps = 48/342 (14%)
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
+ R L + D L A S AGA +++ +R P I PR R G
Sbjct: 3544 RATRVLRVRDAGLYTCLAESPAGA-----IEKSFRVRVQAP-PNIVGPRGPRFVVGLAPG 3597
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ V L+ + +P P+ TW +G L + ++ L +++ +DSG Y T R
Sbjct: 3598 QLV-LECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRFLQLQALSTADSGDYSCTAR 3655
Query: 250 ----VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
+ + I + + GPP+ N ++ T LL
Sbjct: 3656 NAAGSTSVAFRVEIHTVPTIRSGPPA---------VNVSVN--------QTALLPCQADG 3698
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN----LCGLSTSATVTKELAHI 361
W P + L G+ V +++ LC S SA ++ +
Sbjct: 3699 VPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL 3758
Query: 362 QKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
+ E P+ ++ T T L C SPKP ++W K+ +
Sbjct: 3759 RVL---------------EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQK 3803
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ + A L + P P DS + C N +GEA
Sbjct: 3804 LDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEA 3845
Score = 38.1 bits (87), Expect = 0.018
Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ D T T L C P P + W K ++ +S G LEI
Sbjct: 3857 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGA--LEI 3914
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
+ P +G YTC A N G A L V+AS
Sbjct: 3915 GQALPIHAGRYTCSARNSAGVAHKHVFLTVQAS 3947
Score = 37.4 bits (85), Expect = 0.030
Identities = 29/108 (26%), Positives = 39/108 (36%), Gaps = 8/108 (7%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI------QGNPK 427
I+ AP T+ D T G S L C P P + W + + G
Sbjct: 778 IQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGS 837
Query: 428 YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ GV E +P D Y C+A NV G+ + RL V A
Sbjct: 838 RSRQPDSGVLFFE--SVAPEDQAPYVCEARNVFGKVQAEARLIVTGHA 883
Score = 37.0 bits (84), Expect = 0.039
Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L C A P P I W K+ + + + + L E + L+I+ DSG Y C A NV
Sbjct: 2659 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVSDSGRYLCVATNVA 2716
Query: 461 GEASVD 466
GE D
Sbjct: 2717 GEDDQD 2722
Score = 36.6 bits (83), Expect = 0.051
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 9/80 (11%)
Query: 394 TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYT 453
TPG +L C + +P+P I W K+ + + + L +R D+G+YT
Sbjct: 3508 TPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN----NSRATRVLRVR-----DAGLYT 3558
Query: 454 CKAINVLGEASVDCRLEVKA 473
C A + G R+ V+A
Sbjct: 3559 CLAESPAGAIEKSFRVRVQA 3578
Score = 36.2 bits (82), Expect = 0.067
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
+ VG ++ L +G P P W +G L +R Q+ L I +R D+GRY
Sbjct: 4229 VEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSH--LRHQLQNGSLTIHRTERDDAGRY 4286
Query: 245 ELTVRVEDLEAKAVIDILVIE 265
+ E AK V+ ILV++
Sbjct: 4287 QCLAENEMGVAKKVV-ILVLQ 4306
Score = 35.8 bits (81), Expect = 0.088
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 385 TQPLADHTSTPGYST-QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
T+ L + + ST L C +P P I W++N + +P+ + L + V L++
Sbjct: 2848 TEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV--LQVST 2905
Query: 444 PSPFDSGVYTCKAINVLGEA 463
D+ Y C A N G A
Sbjct: 2906 AEVADAASYMCVAENQAGSA 2925
Score = 34.7 bits (78), Expect = 0.20
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 10/88 (11%)
Query: 388 LADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR----ALSEQGVCTLEIRK 443
L T+ G +L C SP P I W++N G P ++ QG TL I
Sbjct: 1696 LGQVTTIVGQPLELPCQASGSPVPTIQWLQN-----GRPAEELAGVQVASQGT-TLHIDH 1749
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEV 471
SG++ C+A N G A + + V
Sbjct: 1750 VELDHSGLFACQATNEAGTAGAEVEVSV 1777
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G +L C P P++ W K++ + + + E G L I D G Y C
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGRYQCV 1481
Query: 456 AINVLGEASVDCRLEVKA 473
A + G+ + D +L V A
Sbjct: 1482 AFSPAGQQARDFQLRVHA 1499
Score = 33.9 bits (76), Expect = 0.33
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C P+P I W K + + + L L I SP D+G Y C A N G
Sbjct: 3969 CEASGIPRPTITWQKEGLNVATGVSTQVLPGG---QLRIAHASPEDAGNYLCIAKNSAGS 4025
Query: 463 ASVDCRLEVK 472
A RL V+
Sbjct: 4026 AMGKTRLVVQ 4035
Score = 32.3 bits (72), Expect = 0.97
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 407 ASPKPKII--WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
A PKP ++ W + + G P ++ L+I K D G+YTC A N+ GE+
Sbjct: 1817 AHPKPPLVEGWC-SPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESK 1875
Query: 465 VDCRLEV 471
+ L+V
Sbjct: 1876 REVALKV 1882
Score = 32.0 bits (71), Expect = 1.3
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 6/110 (5%)
Query: 138 GDKFLLRVSAVSSAGAGP-----PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETV 192
G +L+ S AGA PA D +H + P I+ T + + GE V
Sbjct: 3272 GGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELV 3331
Query: 193 NLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
+ P +G P +W +G L + ++ G + L I Q +D+G
Sbjct: 3332 TMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT-LRISKVQLADAG 3380
Score = 30.0 bits (66), Expect = 4.8
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 146 SAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQ 205
S V+S+ AG A+L + ++ P++ V L Q VG+ + L G P P
Sbjct: 1666 SCVASSPAGE-AVLQYSVEVQV---PPQLLVAEGLGQV-TTIVGQPLELPCQASGSPVPT 1720
Query: 206 ATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILV 263
W NG + + ++ Q + L I + SG + E A A +++ V
Sbjct: 1721 IQWLQNGRPAE-ELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777
Score = 30.0 bits (66), Expect = 4.8
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRV-SMR 223
+R N+ P+I +P L + V V L G P P W +G+ + ++
Sbjct: 1971 LRVNVP-PRITLPPSLPGPVL--VNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQ 2027
Query: 224 TGDQDSILFIRSAQRSDSGRY 244
+L + SA+ SDSGRY
Sbjct: 2028 VFPGGRVLTLASARASDSGRY 2048
Score = 29.6 bits (65), Expect = 6.3
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 171 APKIRVPRHLRQTYIRQV---GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ 227
A K+ VP ++ + + +V L+ G P P +W GH S + +
Sbjct: 1879 ALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSW-FKGHQPVSSWMGVTVSVD 1937
Query: 228 DSILFIRSAQRSDSGRY 244
+L I AQ SD+G Y
Sbjct: 1938 GRVLRIEQAQLSDAGSY 1954
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 70.1 bits (170), Expect = 4e-12
Identities = 100/378 (26%), Positives = 146/378 (38%), Gaps = 91/378 (24%)
Query: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAG--------PPAMLDQPIHIRENIEAPKIR 175
P+ ++Q+T+ + G LR+S V A AG P + D+ ++ ++ P +
Sbjct: 2071 PLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQ--VQVPPVL 2125
Query: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRS 235
P + + G V L +G P P +W +G L SQ + +Q L + +
Sbjct: 2126 EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL-----EQGPSLQLEA 2180
Query: 236 AQRSDSGRYELTVRVEDLEAKAVIDILVIEKP-----GPPSSIRLLDVWG----CNAALQ 286
DSG Y E EA+ + V+E P G P+ + L C+A Q
Sbjct: 2181 VGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDA--Q 2238
Query: 287 WTP-PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345
TP P T + K GQ T LE NS + RV
Sbjct: 2239 GTPQPNITWH-------------KDGQALTRLEN--------------NSRATRVLRVRD 2271
Query: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFS------------EAPSFTQPLADHTS 393
GL T +A P G IE+ F P F LA
Sbjct: 2272 AGLYTC--------------LAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLA---- 2313
Query: 394 TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYT 453
PG L CSV A P PKI W ++ + +Q + + E+G L+++ S DSG Y+
Sbjct: 2314 -PGQLV-LECSVEAEPAPKITWHRDGIVLQEDA-HTQFPERGRF-LQLQALSTADSGDYS 2369
Query: 454 CKAINVLGEASVDCRLEV 471
C A N G SV R+E+
Sbjct: 2370 CTARNAAGSTSVAFRVEI 2387
Score = 53.9 bits (128), Expect = 3e-07
Identities = 76/313 (24%), Positives = 121/313 (38%), Gaps = 49/313 (15%)
Query: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
AP+IR R+ ++ + G+ V L G+P P W +G L +R
Sbjct: 1933 APRIRSSGVAREHHVLE-GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG 1991
Query: 230 ILFIRSAQRSDSGRYELTVR---VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQ 286
L ++ + SD+G Y ED V ++LV PP+ + D G
Sbjct: 1992 SLVLKGLRASDAGAYTCVAHNPAGEDARLHTV-NVLV-----PPTIKQGADGSG------ 2039
Query: 287 WTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL- 345
T G + V+ + W L+ P + L+ G+ ++ R+ L
Sbjct: 2040 -TLVSRPGELVTMVCPVRGSPPIHVSW---LKDGLPLPLSQRTLLHGSGHTLRISKVQLA 2095
Query: 346 -CGLSTSATVTKELAHIQKADIAAKPKGFIERDFS---EAPSFTQPLA---DHTSTPGYS 398
G+ T +AA P G +R+F+ + P +P+ D G
Sbjct: 2096 DAGIFTC--------------VAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSL 2141
Query: 399 TQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAIN 458
+L C R P P + WMK+ G P EQG +L++ DSG Y+C A++
Sbjct: 2142 VELPCEARGVPLPLVSWMKD-----GEPLLSQSLEQGP-SLQLEAVGAGDSGTYSCVAVS 2195
Query: 459 VLGEASVDCRLEV 471
GEA +L V
Sbjct: 2196 EAGEARRHFQLTV 2208
Score = 49.7 bits (117), Expect = 6e-06
Identities = 76/309 (24%), Positives = 119/309 (38%), Gaps = 40/309 (12%)
Query: 172 PKIRVPRHL-RQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI 230
P+I PR Q + Q G L+ GKP P TW +G + ++ + ++ +Q
Sbjct: 974 PQIAGPREPPTQVSVVQDG-VATLECNATGKPPPTVTWERDGQPVGAE-LGLQLQNQGQS 1031
Query: 231 LFIRSAQRSDSGRYELTVR--VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288
L + AQ + +GRY E K + +LV PP I LD A +
Sbjct: 1032 LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV-----PPELIGDLDPLTNITAALHS 1086
Query: 289 PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348
P T E +G +WF E P T L+ G G
Sbjct: 1087 PL--TLLCEAMGIPPPAI-----RWFRGEEPVSPGEDTY--LLAG-------------GW 1124
Query: 349 STSATVTKELAHIQKADIAAKPKGFIERDFSEA----PSFTQPLADHTST--PGYSTQLF 402
T T+E + +A+ G R+FS PS + G + L
Sbjct: 1125 MLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLM 1184
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C+V P+PK+ W K+ + + +S GV L++ + + +G Y+C A N +GE
Sbjct: 1185 CNVTGHPQPKLTWFKDGRPLARGDAHH-ISPDGV-LLQVLQANLSSAGHYSCIAANAVGE 1242
Query: 463 ASVDCRLEV 471
+ +L V
Sbjct: 1243 KTKHFQLSV 1251
Score = 49.7 bits (117), Expect = 6e-06
Identities = 70/342 (20%), Positives = 124/342 (36%), Gaps = 41/342 (11%)
Query: 137 LGDKFLLRVSAVSSAGAGP-PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV----GET 191
L D +L+VS A A + + E + +++VP + + QV +
Sbjct: 1613 LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSS 1672
Query: 192 VNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
V+L P P+ TW + AL + V + G L + A+ SDSG Y
Sbjct: 1673 VSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT--LQLGRARLSDSGMYTCEALN 1730
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT-----GNTELLGYMVQK 305
+ ++ + V+ P + R PQD G+ +L
Sbjct: 1731 AAGRDQKLVQLSVLVPPAFRQAPR--------------GPQDAVLVRVGDKAVLSCETDA 1776
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
+ T W+ + L++ + L + + K L + ++
Sbjct: 1777 LPEPTVTWYKDGQ----------PLVLAQRTQALRGGQRL-EIQEAQVSDKGLYSCKVSN 1825
Query: 366 IAAKPKGFIERDFSEAPSFTQPLADHTS-TPGYSTQLFCSVRASPKPKIIWMKNKMEIQG 424
+A + P+F P + S G L C V P P + W+K++M ++
Sbjct: 1826 VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVES 1885
Query: 425 NPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVD 466
+ + +S G L++ + P +G YTC A N EA D
Sbjct: 1886 SAVHGVVSRGG--RLQLSRLQPAQAGTYTCVAENTQAEARKD 1925
Score = 49.3 bits (116), Expect = 8e-06
Identities = 62/271 (22%), Positives = 110/271 (40%), Gaps = 41/271 (15%)
Query: 199 QGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
+G P+P TW +G + T L +++ + D+G Y T A+
Sbjct: 2780 RGSPEPNITWDKDGQPVSGAEGKF-TIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR 2838
Query: 259 IDILVIEKP-----GPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQW 313
+ + ++ P S+RL D A + +P T +G+ V G
Sbjct: 2839 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSP------TPRIGWTVNDRPVTEG-- 2890
Query: 314 FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGF 373
V E+ +T + + +S ++ ++EN G + + + H+++A +
Sbjct: 2891 --VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVS----FVHVKEAPVLQ----- 2939
Query: 374 IERDFSEAPSF-TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALS 432
EA S+ +P+ G S QL C VR P P I W+K+ + ++G+ L
Sbjct: 2940 -----GEAFSYLVEPV-------GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ 2987
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+L IR+ D+G Y C A N +G A
Sbjct: 2988 NG---SLTIRRTERDDAGRYQCLAENEMGVA 3015
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
QL C R P P I W K+ + + K + +G L++ + D+GVYTCKA N
Sbjct: 239 QLLCEARGVPTPNITWFKDGALLPTSTK--VVYTRGGRQLQLGRAQSSDAGVYTCKASNA 296
Query: 460 LGEASVDCRLEV 471
+G A RL+V
Sbjct: 297 VGAAEKATRLDV 308
Score = 47.8 bits (112), Expect = 2e-05
Identities = 70/282 (24%), Positives = 113/282 (40%), Gaps = 40/282 (14%)
Query: 191 TVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRV 250
TV+LQ P G P P +W NG S ++ + +L + +A+ +D+ Y + V
Sbjct: 1580 TVSLQCPALGNPVPTISWLQNGLPF-SPSPRLQVLEDGQVLQVSTAEVADAASY---MCV 1635
Query: 251 EDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP--PQDT---GNTELLGYMVQK 305
+ +A + + + PP I LD+ A L + P D N E+ Y +
Sbjct: 1636 AENQAGSAEKLFTLRVQVPP-RIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 1694
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKAD 365
A + F + P T T+ +G + LS S T E +
Sbjct: 1695 ALSLGEEVFLL-----PGTHTLQ---LGRA-----------RLSDSGMYTCE-----ALN 1730
Query: 366 IAAKPKGFIERDFSEAPSFTQ----PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
A + + ++ P+F Q P G L C A P+P + W K+
Sbjct: 1731 AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQP 1790
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ + +AL +G LEI++ D G+Y+CK NV GEA
Sbjct: 1791 LVLAQRTQAL--RGGQRLEIQEAQVSDKGLYSCKVSNVAGEA 1830
Score = 45.8 bits (107), Expect = 8e-05
Identities = 40/132 (30%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 356 KELAHIQKADI---------AAKPKGFIERDFS----EAPSFTQPLAD-HTST--PGYST 399
K L + +AD+ A G E+ ++ AP F PL + HT T G+ T
Sbjct: 841 KALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVF--PLRESHTLTVREGHPT 898
Query: 400 QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
+L C R P PKI W K+ + G L + + G YTC+ NV
Sbjct: 899 RLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNV 958
Query: 460 LGEASVDCRLEV 471
+G +S D +LEV
Sbjct: 959 VGNSSQDLQLEV 970
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P L D ++T G L C R SP+P I W K+ + G + G L +
Sbjct: 2756 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLV 2813
Query: 442 RKPSPFDSGVYTCKAINVLGEA 463
+ D+G YTC A N +G A
Sbjct: 2814 KNLEGQDAGTYTCTAENAVGRA 2835
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 392 TSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGV 451
T T L C A P P I WMK+ + + + L G L+I D+G
Sbjct: 1270 TVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKEDAGQ 1327
Query: 452 YTCKAINVLGEASVDCRLEV 471
YTC N LGEA + +EV
Sbjct: 1328 YTCVVTNELGEAVKNYHVEV 1347
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 24/169 (14%)
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKA 364
K + W V I + ++ S+R + N+ G + EL + +
Sbjct: 639 KGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAG-------STELRYGLRV 691
Query: 365 DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMK--NKMEI 422
++ + + PS P+ +T +L C+ +P P ++W+K N +
Sbjct: 692 NVPPR--------ITLPPSLPGPVLVNTPV-----RLTCNATGAPSPTLMWLKDGNPVSP 738
Query: 423 QGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
G P + V TL + S DSG Y+C A++ +GE D L+V
Sbjct: 739 AGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVLQV 785
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 6/92 (6%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQ-GVCTLE 440
P FT D + G L C+ R SP P+I W N P +SEQ G TL+
Sbjct: 2847 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVND-----RPVTEGVSEQDGGSTLQ 2901
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
S DSG Y C A N +G + VK
Sbjct: 2902 RAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 2933
Score = 40.4 bits (93), Expect = 0.004
Identities = 61/275 (22%), Positives = 104/275 (37%), Gaps = 28/275 (10%)
Query: 202 PKPQATWTHNGHALDSQR-VSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEA--KAV 258
P P TW +G ++ R + + G L I +AQ+ D+G+Y V E EA
Sbjct: 1287 PSPNITWMKDGAPFEASRNIQLLPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYH 1344
Query: 259 IDILV---IEKPGPPSSIRLLDV-WGCNAAL-----QWTPPQDTGNTELLGYMVQKADKK 309
+++L+ I K P + + + +V N+ L W P T G V + +
Sbjct: 1345 VEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRL 1404
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSA--TVTKELAHIQKADIA 367
L + PT + +S + + N+ G + + QK
Sbjct: 1405 QVLGEGRLLQIQPTQ-------VSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDF 1457
Query: 368 AKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPK 427
+ + R+ T+ + P Y L+C A P P + W + + +
Sbjct: 1458 SAAFEILSREEEARGGVTEYREIVENNPAY---LYCDTNAIPPPDLTWYREDQPLSAGDE 1514
Query: 428 YRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
L QG L+I ++G Y+CKA N +GE
Sbjct: 1515 VSVL--QGGRVLQIPLVRAENAGRYSCKASNEVGE 1547
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 393 STPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVY 452
S PG + C VR SP + W+K+ + + R L TL I K D+G++
Sbjct: 2043 SRPGELVTMVCPVRGSPPIHVSWLKDGLPLP--LSQRTLLHGSGHTLRISKVQLADAGIF 2100
Query: 453 TCKAINVLGEASVDCRLEVK 472
TC A + G A + L+V+
Sbjct: 2101 TCVAASPAGVADRNFTLQVQ 2120
Score = 40.0 bits (92), Expect = 0.005
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 3/92 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP F D T G L C P P I W++ ++ + + R L + +L
Sbjct: 3026 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---SLW 3082
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ D+G Y C A N+LG A+ L V+
Sbjct: 3083 LENVETGDAGTYDCVAHNLLGSATARAFLVVR 3114
Score = 39.3 bits (90), Expect = 0.008
Identities = 65/310 (20%), Positives = 110/310 (35%), Gaps = 59/310 (19%)
Query: 182 QTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDS 241
Q + G V LQ G P PQ WT + + ++ + +L I + D
Sbjct: 134 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDE 193
Query: 242 GRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL-G 300
GRY+ + + V PP+ +WG N +TG ++
Sbjct: 194 GRYQCVAFSPAGQQARDFQLRV---HAPPT------IWGSN---------ETGEVAVMED 235
Query: 301 YMVQKADKKTG------QWFTVLERYHPTTCTI-----SDLIIGNSYS-----FRVFSEN 344
++VQ + G WF +T + L +G + S + + N
Sbjct: 236 HLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASN 295
Query: 345 LCGLSTSATVTKELAHIQKADIAAKP--KGFIERDFSEAPSFTQPLADHTSTPGYSTQLF 402
G + AT + D+ P +G R + +P+A L
Sbjct: 296 AVGAAEKAT---------RLDVYVPPTIEGAGGRPYVVKAVAGRPVA-----------LE 335
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C R P P + W + + + + R ++ V LE P SG+Y+C A + GE
Sbjct: 336 CVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLE--SPGEASSGLYSCVASSPAGE 393
Query: 463 ASVDCRLEVK 472
A + +EV+
Sbjct: 394 AVLQYSVEVQ 403
Score = 39.3 bits (90), Expect = 0.008
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 398 STQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
S L C A P P + W K+ ++ P +++ + L++ + +D+G YTC+A+
Sbjct: 805 SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEAL 862
Query: 458 NVLGEASVDCRLEV 471
N G + L V
Sbjct: 863 NQAGHSEKHYNLNV 876
Score = 39.3 bits (90), Expect = 0.008
Identities = 72/342 (21%), Positives = 119/342 (34%), Gaps = 48/342 (14%)
Query: 130 QTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVG 189
+ R L + D L A S AGA +++ +R P I PR R G
Sbjct: 2262 RATRVLRVRDAGLYTCLAESPAGA-----IEKSFRVRVQAP-PNIVGPRGPRFVVGLAPG 2315
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
+ V L+ + +P P+ TW +G L + ++ L +++ +DSG Y T R
Sbjct: 2316 QLV-LECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRFLQLQALSTADSGDYSCTAR 2373
Query: 250 ----VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQK 305
+ + I + + GPP+ N ++ T LL
Sbjct: 2374 NAAGSTSVAFRVEIHTVPTIRSGPPA---------VNVSVN--------QTALLPCQADG 2416
Query: 306 ADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSEN----LCGLSTSATVTKELAHI 361
W P + L G+ V +++ LC S SA ++ +
Sbjct: 2417 VPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL 2476
Query: 362 QKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKME 421
+ E P+ ++ T T L C SPKP ++W K+ +
Sbjct: 2477 RVL---------------EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQK 2521
Query: 422 IQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
+ + A L + P P DS + C N +GEA
Sbjct: 2522 LDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEA 2563
Score = 38.1 bits (87), Expect = 0.018
Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P+ D T T L C P P + W K ++ +S G LEI
Sbjct: 2575 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGA--LEI 2632
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
+ P +G YTC A N G A L V+AS
Sbjct: 2633 GQALPIHAGRYTCSARNSAGVAHKHVFLTVQAS 2665
Score = 38.1 bits (87), Expect = 0.018
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
+ VG ++ L +G P P W +G L +R Q+ L IR +R D+GRY
Sbjct: 2947 VEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSH--LRHQLQNGSLTIRRTERDDAGRY 3004
Query: 245 ELTVRVEDLEAKAVIDILVIE 265
+ E AK V+ ILV++
Sbjct: 3005 QCLAENEMGVAKKVV-ILVLQ 3024
Score = 37.0 bits (84), Expect = 0.039
Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
L C A P P I W K+ + + + + L E + L+I+ DSG Y C A NV
Sbjct: 1377 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVSDSGRYLCVATNVA 1434
Query: 461 GEASVD 466
GE D
Sbjct: 1435 GEDDQD 1440
Score = 36.6 bits (83), Expect = 0.051
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 9/80 (11%)
Query: 394 TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYT 453
TPG +L C + +P+P I W K+ + + + L +R D+G+YT
Sbjct: 2226 TPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN----NSRATRVLRVR-----DAGLYT 2276
Query: 454 CKAINVLGEASVDCRLEVKA 473
C A + G R+ V+A
Sbjct: 2277 CLAESPAGAIEKSFRVRVQA 2296
Score = 35.8 bits (81), Expect = 0.088
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 385 TQPLADHTSTPGYST-QLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
T+ L + + ST L C +P P I W++N + +P+ + L + V L++
Sbjct: 1566 TEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV--LQVST 1623
Query: 444 PSPFDSGVYTCKAINVLGEA 463
D+ Y C A N G A
Sbjct: 1624 AEVADAASYMCVAENQAGSA 1643
Score = 34.7 bits (78), Expect = 0.20
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 10/88 (11%)
Query: 388 LADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR----ALSEQGVCTLEIRK 443
L T+ G +L C SP P I W++N G P ++ QG TL I
Sbjct: 414 LGQVTTIVGQPLELPCQASGSPVPTIQWLQN-----GRPAEELAGVQVASQGT-TLHIDH 467
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEV 471
SG++ C+A N G A + + V
Sbjct: 468 VELDHSGLFACQATNEAGTAGAEVEVSV 495
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G +L C P P++ W K++ + + + E G L I D G Y C
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGRYQCV 199
Query: 456 AINVLGEASVDCRLEVKA 473
A + G+ + D +L V A
Sbjct: 200 AFSPAGQQARDFQLRVHA 217
Score = 33.9 bits (76), Expect = 0.33
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 19/99 (19%)
Query: 389 ADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNP----------------KYRALS 432
A+ + G S L C P P+I+W+K+ ++ G P +R L
Sbjct: 26 ANVSGMAGQSLTLECDANGFPVPEIVWLKD-AQLVGVPLGWAGYGWDLGWGQVGGHRLLD 84
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
E +L + DSG+Y+C+A N G A D L V
Sbjct: 85 EGQ--SLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLV 121
Score = 33.9 bits (76), Expect = 0.33
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 403 CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGE 462
C P+P I W K + + + L L I SP D+G Y C A N G
Sbjct: 2687 CEASGIPRPTITWQKEGLNVATGVSTQVLPGG---QLRIAHASPEDAGNYLCIAKNSAGS 2743
Query: 463 ASVDCRLEVK 472
A RL V+
Sbjct: 2744 AMGKTRLVVQ 2753
Score = 32.3 bits (72), Expect = 0.97
Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 407 ASPKPKII--WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464
A PKP ++ W + + G P ++ L+I K D G+YTC A N+ GE+
Sbjct: 535 AHPKPPLVEGWC-SPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESK 593
Query: 465 VDCRLEV 471
+ L+V
Sbjct: 594 REVALKV 600
Score = 32.0 bits (71), Expect = 1.3
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 6/110 (5%)
Query: 138 GDKFLLRVSAVSSAGAGP-----PAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETV 192
G +L+ S AGA PA D +H + P I+ T + + GE V
Sbjct: 1990 GGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELV 2049
Query: 193 NLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
+ P +G P +W +G L + ++ G + L I Q +D+G
Sbjct: 2050 TMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT-LRISKVQLADAG 2098
Score = 30.0 bits (66), Expect = 4.8
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 146 SAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQ 205
S V+S+ AG A+L + ++ P++ V L Q VG+ + L G P P
Sbjct: 384 SCVASSPAGE-AVLQYSVEVQV---PPQLLVAEGLGQV-TTIVGQPLELPCQASGSPVPT 438
Query: 206 ATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILV 263
W NG + + ++ Q + L I + SG + E A A +++ V
Sbjct: 439 IQWLQNGRPAE-ELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 495
Score = 30.0 bits (66), Expect = 4.8
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 165 IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRV-SMR 223
+R N+ P+I +P L + V V L G P P W +G+ + ++
Sbjct: 689 LRVNVP-PRITLPPSLPGPVL--VNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQ 745
Query: 224 TGDQDSILFIRSAQRSDSGRY 244
+L + SA+ SDSGRY
Sbjct: 746 VFPGGRVLTLASARASDSGRY 766
Score = 29.6 bits (65), Expect = 6.3
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 171 APKIRVPRHLRQTYIRQV---GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ 227
A K+ VP ++ + + +V L+ G P P +W GH S + +
Sbjct: 597 ALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSW-FKGHQPVSSWMGVTVSVD 655
Query: 228 DSILFIRSAQRSDSGRY 244
+L I AQ SD+G Y
Sbjct: 656 GRVLRIEQAQLSDAGSY 672
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 66.6 bits (161), Expect = 5e-11
Identities = 71/259 (27%), Positives = 100/259 (38%), Gaps = 29/259 (11%)
Query: 202 PKPQATWTHNGHAL---DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
P +A+W NG A+ DS G ++L +RSAQ +G E+T D A A
Sbjct: 4460 PVGEASWYINGAAVQPDDSDWTVTADGSHHALL-LRSAQPHHAG--EVTFACRDAVASAR 4516
Query: 259 IDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
+ +L + P PP ++ L W P G L GY V+ + TGQW E
Sbjct: 4517 LTVLGL--PDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHE 4574
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHI-QKADIAAKPKGFIERD 377
C + L G +Y FRV + G E H+ Q +A PK
Sbjct: 4575 LVPGPECVVDGLAPGETYRFRVAAVGPVGAG-------EPVHLPQTVRLAEPPK------ 4621
Query: 378 FSEAPSFTQPLADHTS--TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG 435
P QP A + G L V A ++IW K IQ ++ +S+
Sbjct: 4622 ----PVPPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPGGRFEVVSQGR 4676
Query: 436 VCTLEIRKPSPFDSGVYTC 454
L I+ + D G Y C
Sbjct: 4677 QQMLVIKGFTAEDQGEYHC 4695
Score = 54.7 bits (130), Expect = 2e-07
Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 378 FSEAPSF-TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGV 436
FS AP F T+P A S G L C + +P P++ W K++ + ++R + +
Sbjct: 6 FSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDL 64
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
L I + DSG Y C+A N +GEA L+V A AA
Sbjct: 65 YRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA 104
Score = 53.5 bits (127), Expect = 4e-07
Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE-QGVCTLE 440
P F + LAD T+ G + +L C V +PKP I W K+ +Q +P + + + G C L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 441 IRKPSPFDSGVYTCKAINVLGEAS 464
+ + DSG Y C A + G S
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCS 6097
Score = 52.4 bits (124), Expect = 9e-07
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE--QGVCTL 439
P F + G Q C++ +P P+I W K+ + K++ LSE G+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
IR S D G+Y C+ +N LG A L +++
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 51.2 bits (121), Expect = 2e-06
Identities = 50/166 (30%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 83 SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFL 142
SS +VT+SW P G GL GY +E+ +EGA+ + + + V LA G+ +
Sbjct: 4535 SSHTVTLSWAAPMSDGGGGLCGYRVEV-KEGATGQWRLCHELVPGPECVVDGLAPGETYR 4593
Query: 143 LRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV--GETVNLQIPFQG 200
RV+AV GAG P L Q + + E P VP RQV GE V+L++
Sbjct: 4594 FRVAAVGPVGAGEPVHLPQTVRLAE----PPKPVPPQPSAPESRQVAAGEDVSLELEVVA 4649
Query: 201 KPKPQATWTHNG--HALDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
+ + W H G R + + + +L I+ D G Y
Sbjct: 4650 E-AGEVIW-HKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 49.3 bits (116), Expect = 8e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 19/173 (10%)
Query: 53 QAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGR-LGLQGYVLELCR 111
Q T + P P P P++ + SSV +SW PP R + + GY++E +
Sbjct: 498 QTSTQFCVSAPRKPPLQPPVDPVVKARME---SSVILSWSPPPHGERPVTIDGYLVEKKK 554
Query: 112 EGASEWVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G W+ + T + TV ++A F RVSA++S G P +H+
Sbjct: 555 LGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHL----- 609
Query: 171 APKIRVPRHLRQTYIRQVGE---TVNLQIPFQGKPKPQATWTHNGHALDSQRV 220
APK+ V L+ + GE +V+L + G+ W +G AL + V
Sbjct: 610 APKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGE------WFLDGQALKASSV 656
Score = 48.1 bits (113), Expect = 2e-05
Identities = 102/469 (21%), Positives = 160/469 (34%), Gaps = 52/469 (11%)
Query: 43 QVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGL 102
++P+ + + P + P SE +A L D S S + R G L
Sbjct: 4760 ELPEEDGRSQRLPQEAEEVAP-DLSEGYSTADELARTGDADLSHT--SSDDESRAGTPSL 4816
Query: 103 QGYVLELCREGASEW---VPVSARPMMVTQQTVRNLA-----LGDKFLLRVSAVSSAGAG 154
Y+ + R G S V A P + QQ LA LGD +S+ G
Sbjct: 4817 VTYLKKAGRPGTSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGD--------LSTKDLG 4868
Query: 155 PPAMLDQPIHIRENIEAPKIRVPRHLRQTYI---------RQVGETVNLQIPFQGKPKPQ 205
P+M + I+ + K+R ++ + QVG+ + L+ K +
Sbjct: 4869 DPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVR 4928
Query: 206 ATWTHNGHALDSQRVSM--RTGDQDSILFIRSAQRSDSGRYELTV--RVEDLEAKAVIDI 261
A W +G L R + GD L I R+D+G Y V + + A + +
Sbjct: 4929 ARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988
Query: 262 LVIEKPGPPSSIRLLDVWGCNAA------LQWTPPQDTGNTELLGYMVQ--KADKKTGQW 313
E SS LD AA + P + + EL + ++ W
Sbjct: 4989 SGSESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW 5048
Query: 314 FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK---P 370
T E H C + + + F E L + ++ ++ P
Sbjct: 5049 QTYREDEH-FICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETP 5107
Query: 371 KGFIERD-------FSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
+ + AP F L + GY C V P P + W K+ ++
Sbjct: 5108 APVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE 5167
Query: 424 GNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ Y +QG L I P D GVY C A N +G +S L V
Sbjct: 5168 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 45.8 bits (107), Expect = 8e-05
Identities = 77/326 (23%), Positives = 122/326 (37%), Gaps = 56/326 (17%)
Query: 177 PRHLRQ--TYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI-LFI 233
PR L + ++ VG+ L G P PQ +W + + + D D L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPG----------PPSSIRLLD----VW 279
DSG+Y R EA A + + V + P+SIR+ + +
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATF 129
Query: 280 GCNA------ALQWT--------PPQDTGNTELLG----YMVQKADKKTGQWFTVLERYH 321
C A+ W+ P E LG ++ A + G + V
Sbjct: 130 RCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENP 189
Query: 322 PTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEA 381
+ + ++ +S + S G ST+A LAH+Q+ A + +G A
Sbjct: 190 LGAASAAAALVVDSDAADTASRP--GTSTAAL----LAHLQRRREAMRAEG--------A 235
Query: 382 PSFTQPLADHTST--PGYSTQLFCSVRASPKPKIIWMKNKM---EIQGNPKYRALSEQGV 436
P+ T T G +L C V PKP+ +W K+ E + + Y E V
Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFV 295
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGE 462
+ K S D G+YTC A N++G+
Sbjct: 296 LKILFCKQS--DRGLYTCTASNLVGQ 319
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/153 (26%), Positives = 58/153 (37%), Gaps = 16/153 (10%)
Query: 326 TISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFT 385
TI DL +G+S + + N G + +A + A A+ +AP F
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAE--------------QAPHFL 113
Query: 386 QPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN--KMEIQGNPKYRALSEQGVCTLEIRK 443
G C V SP+P + W K+ ++ P+ R L IR
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
P D G Y +A N LG AS L V + AA
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAALVVDSDAA 206
Score = 45.1 bits (105), Expect = 1e-04
Identities = 71/338 (21%), Positives = 131/338 (38%), Gaps = 48/338 (14%)
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T+ +L L D + V A ++ + + + P+ ++ +E QT +
Sbjct: 1956 TISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEP----------QTVEERSSV 2005
Query: 191 TVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
T+ +++ +P P+ WT N AL + V + L + + +D G +
Sbjct: 2006 TLEVELT---RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETP 2062
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ +AK +++ + ++ + +Q + G+ G Q+
Sbjct: 2063 DDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQ---- 2118
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK 369
G + R T T+S L +S VF G+ TSA +
Sbjct: 2119 -GPTCHLAVRGPMHTLTLSGLRPEDS-GLMVFKAE--GVHTSARLV-------------- 2160
Query: 370 PKGFIERDFSEAP-SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKY 428
+E P SF++PL D +T L C + + P + W+K+ +E++ K
Sbjct: 2161 --------VTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAG-KT 2210
Query: 429 RALSEQGVC-TLEIRKPSPFDSGVYTCKAINVLGEASV 465
A++ QG C +L I + D GVY C A + ASV
Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASV 2248
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 322 PTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERD---F 378
P T+ +G+S F+ + V +E A ++ +G +
Sbjct: 2767 PAMWTVGGKTVGSSSRFQATRQG----RKYILVVREAAPSDAGEVVFSVRGLTSKASLIV 2822
Query: 379 SEAPS-FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
E P+ +PL D PG +L C + + P + W+K++ I+ + KY + E +
Sbjct: 2823 RERPAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMA 2881
Query: 438 TLEIRKPSPFDSGVYTCK 455
L IR S D+G YTC+
Sbjct: 2882 MLVIRGASLKDAGEYTCE 2899
Score = 43.1 bits (100), Expect = 5e-04
Identities = 46/152 (30%), Positives = 71/152 (46%), Gaps = 16/152 (10%)
Query: 131 TVRNLALGD--KFLLRV-SAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR- 186
T+ +LALGD +++ R +A+ A A +D E +AP LR T IR
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAE--QAPHFL----LRPTSIRV 121
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTGDQDSILFIRSAQRSDSGR 243
+ G + G P+P +W+ +G L D RV + + S L IR+A+ D G
Sbjct: 122 REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181
Query: 244 YELTVRVED-LEAKAVIDILVIEKPGPPSSIR 274
YE VR E+ L A + LV++ ++ R
Sbjct: 182 YE--VRAENPLGAASAAAALVVDSDAADTASR 211
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLF-CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG 435
D + P + L D PG F V+ P P++ W K+ + + R ++
Sbjct: 5255 DEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKI 5314
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ TLEI + DSG Y N +G A RL V+
Sbjct: 5315 LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
T+PL T S L C R +PK + W K+ + + K++ E + L I +
Sbjct: 2472 TRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRL 2530
Query: 445 SPFDSGVYTCKA 456
P D+GVY C+A
Sbjct: 2531 MPADAGVYRCQA 2542
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI-QGNPKYRALSEQGVCT 438
E P F+ D + G + +L C V + + W+K+ +E+ G + G C+
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCS 4955
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
L I D+G YTC+ N G+ + + V S
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGS 4991
Score = 38.9 bits (89), Expect = 0.010
Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F + L D ++ + L C V + P+ ++W K+ +++ + KY L G L +
Sbjct: 2649 FLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHD 2707
Query: 444 PSPFDSGVYTC 454
SP D+G+YTC
Sbjct: 2708 VSPEDAGLYTC 2718
Score = 38.9 bits (89), Expect = 0.010
Identities = 64/282 (22%), Positives = 108/282 (38%), Gaps = 53/282 (18%)
Query: 206 ATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVI 264
A WT G + S R + IL +R A SD+G E+ V L +KA ++V
Sbjct: 2768 AMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG--EVVFSVRGLTSKA--SLIVR 2823
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDT---------GNTELLGYMVQKADKKTGQWFT 315
E+P + I+ L+ QW P + T + +KA +K+ ++
Sbjct: 2824 ERPA--AIIKPLED-------QWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDV 2874
Query: 316 VLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIE 375
V E T++ L+I + S + E C + S + H+++
Sbjct: 2875 VCEG------TMAMLVIRGA-SLKDAGEYTCEVEASKSTAS--LHVEE------------ 2913
Query: 376 RDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG 435
+A FT+ L + T +F P + W K +E++ + K++ E
Sbjct: 2914 ----KANCFTEELTN-LQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGL 2968
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
L I DS YTC +G+A +L V+ H
Sbjct: 2969 TLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGRRVH 3006
Score = 36.2 bits (82), Expect = 0.067
Identities = 83/378 (21%), Positives = 140/378 (37%), Gaps = 75/378 (19%)
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
A+E + A+P T+R LAL D + A + + ++P +
Sbjct: 3047 ANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDAT 3106
Query: 174 IRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILF 232
I L V ET IP WT +G L S R + + L
Sbjct: 3107 ITEGEDLTL-----VCETSTCDIP--------VCWTKDGKTLRGSARCQLSHEGHRAQLL 3153
Query: 233 IRSAQRSDSGRYELT---------VRVEDLEAK---AVIDILVIEKPGPPSSIRLLDVWG 280
I A DSGRY+ VRV + A+ D+ V+E G +++R + +
Sbjct: 3154 ITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLE--GGAATLRCV-LSS 3210
Query: 281 CNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRV 340
A ++W GN L + G +++ + + +L +S +
Sbjct: 3211 VAAPVKWC----YGNNVL----------RPGDKYSLRQEGAMLELVVRNLRPQDSGRY-- 3254
Query: 341 FSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
S + +TSAT+T + A P FI + L + +T G +
Sbjct: 3255 -SCSFGDQTTSATLT----------VTALPAQFIGK-----------LRNKEATEGATAT 3292
Query: 401 LFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
L C + +A+P + W K ++ +Y + +C L+IR + D+ Y+C V
Sbjct: 3293 LRCELSKAAP---VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC----V 3345
Query: 460 LGEASVDCRLEVKASAAH 477
GE L ++ AH
Sbjct: 3346 CGEERTSASLTIRPMPAH 3363
Score = 35.8 bits (81), Expect = 0.088
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHA--LDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
++GETV L G PKP +W +G A +D + + D L + S DSG+Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Score = 35.4 bits (80), Expect = 0.11
Identities = 65/302 (21%), Positives = 108/302 (35%), Gaps = 46/302 (15%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKP-------KPQATWTHNGHALDSQRVS 221
+EA K H+ + E NLQ+ +G P AT T L+ +
Sbjct: 2900 VEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASG 2959
Query: 222 MRTGDQDSI---LFIRSAQRSDSGRYELTVRVEDLEAKAVID---ILVIEKPGPPSSIRL 275
Q+ + L I + +++DS Y + A+ ++ + +IE +
Sbjct: 2960 KHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIE------DLED 3013
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
+DV G++ + A+ + WF H D G
Sbjct: 3014 VDV-------------QEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGG- 3059
Query: 336 YSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS-FTQPLADHTST 394
+ V + L S T+ E A Q+A A + +E PS F++ L D T T
Sbjct: 3060 --YHVLTLRQLALKDSGTIYFE-AGDQRASAALR--------VTEKPSVFSRELTDATIT 3108
Query: 395 PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
G L C P + W K+ ++G+ + + E L I + DSG Y C
Sbjct: 3109 EGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC 3167
Query: 455 KA 456
+A
Sbjct: 3168 EA 3169
Score = 35.0 bits (79), Expect = 0.15
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 384 FTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
F + L + +T G + L+C + +A+P + W K ++ ++ + C L+IR
Sbjct: 3716 FIEGLRNEEATEGDTATLWCELSKAAP---VEWRKGHETLRDGDRHSLRQDGSRCELQIR 3772
Query: 443 KPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ D+G Y+C V G+ L V+A A
Sbjct: 3773 GLAVVDAGEYSC----VCGQERTSATLTVRALPA 3802
Score = 34.7 bits (78), Expect = 0.20
Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 5/93 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR--VSMRTGDQDSILFIRSAQRSDSGRYEL 246
G+ L G+PKP+ W +G + R V ++ +L I ++SD G Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLY-- 309
Query: 247 TVRVEDLEAKAVIDIL-VIEKPGPPSSIRLLDV 278
T +L + +L V+ +P P RL D+
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDL 342
Score = 34.7 bits (78), Expect = 0.20
Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKII-WMKNKMEIQGNPKYRALS 432
+E SE P +PL + + + A+P + W+K+ +EI+ + ++ S
Sbjct: 1714 LEPQISERPCRREPLV----VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETAS 1769
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ TL + DS +Y+C+ +G D ++V+ AA
Sbjct: 1770 QGDTHTLTVHGAQVLDSAIYSCR----VGAEGQDFPVQVEEVAA 1809
Score = 34.7 bits (78), Expect = 0.20
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 383 SFTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
+ +PL D + + L C V RAS + + W K E+Q PKY +S+ L I
Sbjct: 2291 TLVRPLRDKIAMEKHRGVLECQVSRASAQVR--WFKGSQELQPGPKYELVSDGLYRKLII 2348
Query: 442 RKPSPFDSGVYTCKAINV 459
D YTC A +V
Sbjct: 2349 SDVHAEDEDTYTCDAGDV 2366
Score = 34.7 bits (78), Expect = 0.20
Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P F +PL + G + L C + + P ++W K +++Q N + + L +
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 442 RKPSPFDSGVYTC 454
+ D+G YTC
Sbjct: 3949 QDLQREDTGEYTC 3961
Score = 33.5 bits (75), Expect = 0.44
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%)
Query: 384 FTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
F L S G + L C + +A+P + W K + ++ ++ + VC L+I
Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAP---VEWRKGRESLRDGDRHSLRQDGAVCELQIC 3420
Query: 443 KPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ D+G Y+C V GE L VKA A
Sbjct: 3421 GLAVADAGEYSC----VCGEERTSATLTVKALPA 3450
Score = 33.1 bits (74), Expect = 0.57
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 384 FTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
F + + + + G + L C + +A+P + W K ++G +Y + C L+I
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAAP---VEWRKGSETLRGGDRYSLRQDGTRCELQIH 3860
Query: 443 KPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
S D+G Y+C V G+ L V+A
Sbjct: 3861 GLSVADTGEYSC----VCGQERTSATLTVRA 3887
Score = 33.1 bits (74), Expect = 0.57
Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKII-WMKNKMEIQGNPKYRALSEQGVCTLE 440
P F L G +L C + + ++ W+K +E+ PKY S+ L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 441 IRKPSPFDSGVYTC 454
I + D+G Y C
Sbjct: 4128 IHQLEAKDTGEYAC 4141
Score = 32.7 bits (73), Expect = 0.74
Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+ L + + G + L+C + S + W K ++ +Y E C L+I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ D+G Y C V G+ L ++A A
Sbjct: 3510 LAMADAGEYLC----VCGQERTSATLTIRALPA 3538
Score = 31.2 bits (69), Expect = 2.2
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G S L C V A + ++ W K+ ++ + K R + + L +++ D+G YTC+
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCE 1331
Query: 456 A 456
A
Sbjct: 1332 A 1332
Score = 31.2 bits (69), Expect = 2.2
Identities = 20/90 (22%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F + + + + G + L C + ++ + W K ++ +Y + C L+IR
Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
+ D+G Y+C V G+ L V+A
Sbjct: 3598 LAMADTGEYSC----VCGQERTSAMLTVRA 3623
Score = 31.2 bits (69), Expect = 2.2
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+ L + +T G + L C + S + W K ++ ++ + C L+IR
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRG 3685
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
D+G Y C + G+ L V+A
Sbjct: 3686 LVAEDAGEYLC----MCGKERTSAMLTVRA 3711
Score = 31.2 bits (69), Expect = 2.2
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 5/78 (6%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDS---ILFIRSAQRSDSGRY- 244
GE +G P PQ W +G L + + S +L IR+A + D G Y
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Query: 245 -ELTVRVEDLEAKAVIDI 261
EL R+ A A + I
Sbjct: 6182 CELVNRLGSARASAELRI 6199
Score = 30.8 bits (68), Expect = 2.8
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G + L C V A P+ ++ W K+ ++ + K R + L +++ D+G Y+C+
Sbjct: 1181 GTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCE 1239
Query: 456 A 456
A
Sbjct: 1240 A 1240
Score = 30.4 bits (67), Expect = 3.7
Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G S L C V A + ++ W K+ ++ + K R + L +++ D+G Y+CK
Sbjct: 1549 GTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCK 1607
Query: 456 A 456
A
Sbjct: 1608 A 1608
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/42 (28%), Positives = 21/42 (50%)
Query: 413 IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
+ W+K+ + PKY + G L +R + D+G+Y C
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778
Score = 29.3 bits (64), Expect = 8.2
Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G S L C V A + ++ W K+ ++ + K R + L +++ D+G Y+C+
Sbjct: 1641 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCE 1699
Query: 456 A 456
A
Sbjct: 1700 A 1700
Score = 29.3 bits (64), Expect = 8.2
Identities = 17/79 (21%), Positives = 30/79 (37%)
Query: 391 HTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSG 450
H T C + + W K +++ KY+ + + L +R D+G
Sbjct: 3987 HQEVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAG 4046
Query: 451 VYTCKAINVLGEASVDCRL 469
YTC + AS+ R+
Sbjct: 4047 DYTCDTGHTQSMASLSVRV 4065
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 66.6 bits (161), Expect = 5e-11
Identities = 71/259 (27%), Positives = 100/259 (38%), Gaps = 29/259 (11%)
Query: 202 PKPQATWTHNGHAL---DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAV 258
P +A+W NG A+ DS G ++L +RSAQ +G E+T D A A
Sbjct: 4460 PVGEASWYINGAAVQPDDSDWTVTADGSHHALL-LRSAQPHHAG--EVTFACRDAVASAR 4516
Query: 259 IDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLE 318
+ +L + P PP ++ L W P G L GY V+ + TGQW E
Sbjct: 4517 LTVLGL--PDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHE 4574
Query: 319 RYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHI-QKADIAAKPKGFIERD 377
C + L G +Y FRV + G E H+ Q +A PK
Sbjct: 4575 LVPGPECVVDGLAPGETYRFRVAAVGPVGAG-------EPVHLPQTVRLAEPPK------ 4621
Query: 378 FSEAPSFTQPLADHTS--TPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG 435
P QP A + G L V A ++IW K IQ ++ +S+
Sbjct: 4622 ----PVPPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPGGRFEVVSQGR 4676
Query: 436 VCTLEIRKPSPFDSGVYTC 454
L I+ + D G Y C
Sbjct: 4677 QQMLVIKGFTAEDQGEYHC 4695
Score = 54.7 bits (130), Expect = 2e-07
Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 378 FSEAPSF-TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGV 436
FS AP F T+P A S G L C + +P P++ W K++ + ++R + +
Sbjct: 6 FSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDL 64
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
L I + DSG Y C+A N +GEA L+V A AA
Sbjct: 65 YRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA 104
Score = 53.5 bits (127), Expect = 4e-07
Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE-QGVCTLE 440
P F + LAD T+ G + +L C V +PKP I W K+ +Q +P + + + G C L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 441 IRKPSPFDSGVYTCKAINVLGEAS 464
+ + DSG Y C A + G S
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCS 6097
Score = 52.4 bits (124), Expect = 9e-07
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE--QGVCTL 439
P F + G Q C++ +P P+I W K+ + K++ LSE G+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
IR S D G+Y C+ +N LG A L +++
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 51.2 bits (121), Expect = 2e-06
Identities = 50/166 (30%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 83 SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFL 142
SS +VT+SW P G GL GY +E+ +EGA+ + + + V LA G+ +
Sbjct: 4535 SSHTVTLSWAAPMSDGGGGLCGYRVEV-KEGATGQWRLCHELVPGPECVVDGLAPGETYR 4593
Query: 143 LRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV--GETVNLQIPFQG 200
RV+AV GAG P L Q + + E P VP RQV GE V+L++
Sbjct: 4594 FRVAAVGPVGAGEPVHLPQTVRLAE----PPKPVPPQPSAPESRQVAAGEDVSLELEVVA 4649
Query: 201 KPKPQATWTHNG--HALDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
+ + W H G R + + + +L I+ D G Y
Sbjct: 4650 E-AGEVIW-HKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 49.3 bits (116), Expect = 8e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 19/173 (10%)
Query: 53 QAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGR-LGLQGYVLELCR 111
Q T + P P P P++ + SSV +SW PP R + + GY++E +
Sbjct: 498 QTSTQFCVSAPRKPPLQPPVDPVVKARME---SSVILSWSPPPHGERPVTIDGYLVEKKK 554
Query: 112 EGASEWVPVSARPMMVTQQ-TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIE 170
G W+ + T + TV ++A F RVSA++S G P +H+
Sbjct: 555 LGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHL----- 609
Query: 171 APKIRVPRHLRQTYIRQVGE---TVNLQIPFQGKPKPQATWTHNGHALDSQRV 220
APK+ V L+ + GE +V+L + G+ W +G AL + V
Sbjct: 610 APKLAVRTPLKAVQAVEGGEVTFSVDLTVASAGE------WFLDGQALKASSV 656
Score = 48.1 bits (113), Expect = 2e-05
Identities = 102/469 (21%), Positives = 160/469 (34%), Gaps = 52/469 (11%)
Query: 43 QVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGL 102
++P+ + + P + P SE +A L D S S + R G L
Sbjct: 4760 ELPEEDGRSQRLPQEAEEVAP-DLSEGYSTADELARTGDADLSHT--SSDDESRAGTPSL 4816
Query: 103 QGYVLELCREGASEW---VPVSARPMMVTQQTVRNLA-----LGDKFLLRVSAVSSAGAG 154
Y+ + R G S V A P + QQ LA LGD +S+ G
Sbjct: 4817 VTYLKKAGRPGTSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGD--------LSTKDLG 4868
Query: 155 PPAMLDQPIHIRENIEAPKIRVPRHLRQTYI---------RQVGETVNLQIPFQGKPKPQ 205
P+M + I+ + K+R ++ + QVG+ + L+ K +
Sbjct: 4869 DPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVR 4928
Query: 206 ATWTHNGHALDSQRVSM--RTGDQDSILFIRSAQRSDSGRYELTV--RVEDLEAKAVIDI 261
A W +G L R + GD L I R+D+G Y V + + A + +
Sbjct: 4929 ARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVV 4988
Query: 262 LVIEKPGPPSSIRLLDVWGCNAA------LQWTPPQDTGNTELLGYMVQ--KADKKTGQW 313
E SS LD AA + P + + EL + ++ W
Sbjct: 4989 SGSESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW 5048
Query: 314 FTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK---P 370
T E H C + + + F E L + ++ ++ P
Sbjct: 5049 QTYREDEH-FICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETP 5107
Query: 371 KGFIERD-------FSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
+ + AP F L + GY C V P P + W K+ ++
Sbjct: 5108 APVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE 5167
Query: 424 GNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ Y +QG L I P D GVY C A N +G +S L V
Sbjct: 5168 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 45.8 bits (107), Expect = 8e-05
Identities = 77/326 (23%), Positives = 122/326 (37%), Gaps = 56/326 (17%)
Query: 177 PRHLRQ--TYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSI-LFI 233
PR L + ++ VG+ L G P PQ +W + + + D D L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 234 RSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPG----------PPSSIRLLD----VW 279
DSG+Y R EA A + + V + P+SIR+ + +
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATF 129
Query: 280 GCNA------ALQWT--------PPQDTGNTELLG----YMVQKADKKTGQWFTVLERYH 321
C A+ W+ P E LG ++ A + G + V
Sbjct: 130 RCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENP 189
Query: 322 PTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEA 381
+ + ++ +S + S G ST+A LAH+Q+ A + +G A
Sbjct: 190 LGAASAAAALVVDSDAADTASRP--GTSTAAL----LAHLQRRREAMRAEG--------A 235
Query: 382 PSFTQPLADHTST--PGYSTQLFCSVRASPKPKIIWMKNKM---EIQGNPKYRALSEQGV 436
P+ T T G +L C V PKP+ +W K+ E + + Y E V
Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFV 295
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGE 462
+ K S D G+YTC A N++G+
Sbjct: 296 LKILFCKQS--DRGLYTCTASNLVGQ 319
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/153 (26%), Positives = 58/153 (37%), Gaps = 16/153 (10%)
Query: 326 TISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFT 385
TI DL +G+S + + N G + +A + A A+ +AP F
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAE--------------QAPHFL 113
Query: 386 QPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN--KMEIQGNPKYRALSEQGVCTLEIRK 443
G C V SP+P + W K+ ++ P+ R L IR
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
P D G Y +A N LG AS L V + AA
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAALVVDSDAA 206
Score = 45.1 bits (105), Expect = 1e-04
Identities = 71/338 (21%), Positives = 131/338 (38%), Gaps = 48/338 (14%)
Query: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGE 190
T+ +L L D + V A ++ + + + P+ ++ +E QT +
Sbjct: 1956 TISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEP----------QTVEERSSV 2005
Query: 191 TVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
T+ +++ +P P+ WT N AL + V + L + + +D G +
Sbjct: 2006 TLEVELT---RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETP 2062
Query: 250 VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
+ +AK +++ + ++ + +Q + G+ G Q+
Sbjct: 2063 DDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQ---- 2118
Query: 310 TGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAK 369
G + R T T+S L +S VF G+ TSA +
Sbjct: 2119 -GPTCHLAVRGPMHTLTLSGLRPEDS-GLMVFKAE--GVHTSARLV-------------- 2160
Query: 370 PKGFIERDFSEAP-SFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKY 428
+E P SF++PL D +T L C + + P + W+K+ +E++ K
Sbjct: 2161 --------VTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAG-KT 2210
Query: 429 RALSEQGVC-TLEIRKPSPFDSGVYTCKAINVLGEASV 465
A++ QG C +L I + D GVY C A + ASV
Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASV 2248
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 322 PTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERD---F 378
P T+ +G+S F+ + V +E A ++ +G +
Sbjct: 2767 PAMWTVGGKTVGSSSRFQATRQG----RKYILVVREAAPSDAGEVVFSVRGLTSKASLIV 2822
Query: 379 SEAPS-FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVC 437
E P+ +PL D PG +L C + + P + W+K++ I+ + KY + E +
Sbjct: 2823 RERPAAIIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMA 2881
Query: 438 TLEIRKPSPFDSGVYTCK 455
L IR S D+G YTC+
Sbjct: 2882 MLVIRGASLKDAGEYTCE 2899
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE 433
I+ + PS + D + G + Q + P+P + W K+ +++ + + E
Sbjct: 6349 IDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQE 6408
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+L +R + D+GVYTC A N G+ V C+ E+
Sbjct: 6409 GTTYSLVLRHVASKDAGVYTCLAQNTGGQ--VLCKAEL 6444
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 376 RDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR-ALSEQ 434
+ + AP+F + L+D T G S L C V A P + W K+ ++ + + + + +
Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516
Query: 435 GVCTLEIRKPSPFDSGVYTCKAINVLG 461
L I D GVYTC N LG
Sbjct: 7517 NFQLLTILVVVAEDLGVYTCSVSNALG 7543
Score = 43.1 bits (100), Expect = 5e-04
Identities = 46/152 (30%), Positives = 71/152 (46%), Gaps = 16/152 (10%)
Query: 131 TVRNLALGD--KFLLRV-SAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIR- 186
T+ +LALGD +++ R +A+ A A +D E +AP LR T IR
Sbjct: 68 TILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAE--QAPHFL----LRPTSIRV 121
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTGDQDSILFIRSAQRSDSGR 243
+ G + G P+P +W+ +G L D RV + + S L IR+A+ D G
Sbjct: 122 REGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGT 181
Query: 244 YELTVRVED-LEAKAVIDILVIEKPGPPSSIR 274
YE VR E+ L A + LV++ ++ R
Sbjct: 182 YE--VRAENPLGAASAAAALVVDSDAADTASR 211
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/234 (24%), Positives = 90/234 (38%), Gaps = 23/234 (9%)
Query: 175 RVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTHNGHALDSQR--VSMRTGDQDSI 230
R P LR+ V G++V L +P QATW+ +G L+S + T +
Sbjct: 7461 RAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQL 7520
Query: 231 LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLD---VWGCNAALQW 287
L I D G Y +V V V+ K PSS D V+ L W
Sbjct: 7521 LTILVVVAEDLGVYTCSV---SNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVW 7577
Query: 288 TPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG 347
P + G + Y+VQ + G W T+ S L G +Y+FR + G
Sbjct: 7578 KPVESYGP---VTYIVQ-CSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAG 7633
Query: 348 LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQL 401
+ ++ ++++ + P + S+ S QPL T T + TQ+
Sbjct: 7634 MGPYSSPSEQV-------LLGGPSHLASEEESQGRS-AQPLPS-TKTFAFQTQI 7678
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLF-CSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG 435
D + P + L D PG F V+ P P++ W K+ + + R ++
Sbjct: 5255 DEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKI 5314
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ TLEI + DSG Y N +G A RL V+
Sbjct: 5315 LHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Score = 40.4 bits (93), Expect = 0.004
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
T+PL T S L C R +PK + W K+ + + K++ E + L I +
Sbjct: 2472 TRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRL 2530
Query: 445 SPFDSGVYTCKA 456
P D+GVY C+A
Sbjct: 2531 MPADAGVYRCQA 2542
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEI-QGNPKYRALSEQGVCT 438
E P F+ D + G + +L C V + + W+K+ +E+ G + G C+
Sbjct: 4896 EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCS 4955
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
L I D+G YTC+ N G+ + + V S
Sbjct: 4956 LLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGS 4991
Score = 38.9 bits (89), Expect = 0.010
Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F + L D ++ + L C V + P+ ++W K+ +++ + KY L G L +
Sbjct: 2649 FLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHD 2707
Query: 444 PSPFDSGVYTC 454
SP D+G+YTC
Sbjct: 2708 VSPEDAGLYTC 2718
Score = 38.9 bits (89), Expect = 0.010
Identities = 64/282 (22%), Positives = 108/282 (38%), Gaps = 53/282 (18%)
Query: 206 ATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVI 264
A WT G + S R + IL +R A SD+G E+ V L +KA ++V
Sbjct: 2768 AMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG--EVVFSVRGLTSKA--SLIVR 2823
Query: 265 EKPGPPSSIRLLDVWGCNAALQWTPPQDT---------GNTELLGYMVQKADKKTGQWFT 315
E+P + I+ L+ QW P + T + +KA +K+ ++
Sbjct: 2824 ERPA--AIIKPLED-------QWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDV 2874
Query: 316 VLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIE 375
V E T++ L+I + S + E C + S + H+++
Sbjct: 2875 VCEG------TMAMLVIRGA-SLKDAGEYTCEVEASKSTAS--LHVEE------------ 2913
Query: 376 RDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG 435
+A FT+ L + T +F P + W K +E++ + K++ E
Sbjct: 2914 ----KANCFTEELTN-LQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGL 2968
Query: 436 VCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
L I DS YTC +G+A +L V+ H
Sbjct: 2969 TLRLTISALEKADSDTYTCD----IGQAQSRAQLLVQGRRVH 3006
Score = 36.2 bits (82), Expect = 0.067
Identities = 83/378 (21%), Positives = 140/378 (37%), Gaps = 75/378 (19%)
Query: 114 ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPK 173
A+E + A+P T+R LAL D + A + + ++P +
Sbjct: 3047 ANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDAT 3106
Query: 174 IRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILF 232
I L V ET IP WT +G L S R + + L
Sbjct: 3107 ITEGEDLTL-----VCETSTCDIP--------VCWTKDGKTLRGSARCQLSHEGHRAQLL 3153
Query: 233 IRSAQRSDSGRYELT---------VRVEDLEAK---AVIDILVIEKPGPPSSIRLLDVWG 280
I A DSGRY+ VRV + A+ D+ V+E G +++R + +
Sbjct: 3154 ITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLE--GGAATLRCV-LSS 3210
Query: 281 CNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRV 340
A ++W GN L + G +++ + + +L +S +
Sbjct: 3211 VAAPVKWC----YGNNVL----------RPGDKYSLRQEGAMLELVVRNLRPQDSGRY-- 3254
Query: 341 FSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQ 400
S + +TSAT+T + A P FI + L + +T G +
Sbjct: 3255 -SCSFGDQTTSATLT----------VTALPAQFIGK-----------LRNKEATEGATAT 3292
Query: 401 LFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINV 459
L C + +A+P + W K ++ +Y + +C L+IR + D+ Y+C V
Sbjct: 3293 LRCELSKAAP---VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC----V 3345
Query: 460 LGEASVDCRLEVKASAAH 477
GE L ++ AH
Sbjct: 3346 CGEERTSASLTIRPMPAH 3363
Score = 35.8 bits (81), Expect = 0.088
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHA--LDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
++GETV L G PKP +W +G A +D + + D L + S DSG+Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Score = 35.4 bits (80), Expect = 0.11
Identities = 65/302 (21%), Positives = 108/302 (35%), Gaps = 46/302 (15%)
Query: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKP-------KPQATWTHNGHALDSQRVS 221
+EA K H+ + E NLQ+ +G P AT T L+ +
Sbjct: 2900 VEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASG 2959
Query: 222 MRTGDQDSI---LFIRSAQRSDSGRYELTVRVEDLEAKAVID---ILVIEKPGPPSSIRL 275
Q+ + L I + +++DS Y + A+ ++ + +IE +
Sbjct: 2960 KHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIE------DLED 3013
Query: 276 LDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
+DV G++ + A+ + WF H D G
Sbjct: 3014 VDV-------------QEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGG- 3059
Query: 336 YSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPS-FTQPLADHTST 394
+ V + L S T+ E A Q+A A + +E PS F++ L D T T
Sbjct: 3060 --YHVLTLRQLALKDSGTIYFE-AGDQRASAALR--------VTEKPSVFSRELTDATIT 3108
Query: 395 PGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
G L C P + W K+ ++G+ + + E L I + DSG Y C
Sbjct: 3109 EGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC 3167
Query: 455 KA 456
+A
Sbjct: 3168 EA 3169
Score = 35.0 bits (79), Expect = 0.15
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 384 FTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
F + L + +T G + L+C + +A+P + W K ++ ++ + C L+IR
Sbjct: 3716 FIEGLRNEEATEGDTATLWCELSKAAP---VEWRKGHETLRDGDRHSLRQDGSRCELQIR 3772
Query: 443 KPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ D+G Y+C V G+ L V+A A
Sbjct: 3773 GLAVVDAGEYSC----VCGQERTSATLTVRALPA 3802
Score = 34.7 bits (78), Expect = 0.20
Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 5/93 (5%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQR--VSMRTGDQDSILFIRSAQRSDSGRYEL 246
G+ L G+PKP+ W +G + R V ++ +L I ++SD G Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLY-- 309
Query: 247 TVRVEDLEAKAVIDIL-VIEKPGPPSSIRLLDV 278
T +L + +L V+ +P P RL D+
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDL 342
Score = 34.7 bits (78), Expect = 0.20
Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 374 IERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKII-WMKNKMEIQGNPKYRALS 432
+E SE P +PL + + + A+P + W+K+ +EI+ + ++ S
Sbjct: 1714 LEPQISERPCRREPLV----VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETAS 1769
Query: 433 EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ TL + DS +Y+C+ +G D ++V+ AA
Sbjct: 1770 QGDTHTLTVHGAQVLDSAIYSCR----VGAEGQDFPVQVEEVAA 1809
Score = 34.7 bits (78), Expect = 0.20
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 383 SFTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
+ +PL D + + L C V RAS + + W K E+Q PKY +S+ L I
Sbjct: 2291 TLVRPLRDKIAMEKHRGVLECQVSRASAQVR--WFKGSQELQPGPKYELVSDGLYRKLII 2348
Query: 442 RKPSPFDSGVYTCKAINV 459
D YTC A +V
Sbjct: 2349 SDVHAEDEDTYTCDAGDV 2366
Score = 34.7 bits (78), Expect = 0.20
Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P F +PL + G + L C + + P ++W K +++Q N + + L +
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 442 RKPSPFDSGVYTC 454
+ D+G YTC
Sbjct: 3949 QDLQREDTGEYTC 3961
Score = 33.5 bits (75), Expect = 0.44
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%)
Query: 384 FTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
F L S G + L C + +A+P + W K + ++ ++ + VC L+I
Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAP---VEWRKGRESLRDGDRHSLRQDGAVCELQIC 3420
Query: 443 KPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ D+G Y+C V GE L VKA A
Sbjct: 3421 GLAVADAGEYSC----VCGEERTSATLTVKALPA 3450
Score = 33.5 bits (75), Expect = 0.44
Identities = 21/87 (24%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNG-HALDSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
Q G T + +G P+P TW + +DS R+S + L +R D+G Y
Sbjct: 6369 QTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 6428
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS 272
+ + ++LV+ P S
Sbjct: 6429 CLAQNTGGQVLCKAELLVLGGDNEPDS 6455
Score = 33.1 bits (74), Expect = 0.57
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 384 FTQPLADHTSTPGYSTQLFCSV-RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIR 442
F + + + + G + L C + +A+P + W K ++G +Y + C L+I
Sbjct: 3804 FIEDVKNQEAREGATAVLQCELSKAAP---VEWRKGSETLRGGDRYSLRQDGTRCELQIH 3860
Query: 443 KPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
S D+G Y+C V G+ L V+A
Sbjct: 3861 GLSVADTGEYSC----VCGQERTSATLTVRA 3887
Score = 33.1 bits (74), Expect = 0.57
Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKII-WMKNKMEIQGNPKYRALSEQGVCTLE 440
P F L G +L C + + ++ W+K +E+ PKY S+ L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 441 IRKPSPFDSGVYTC 454
I + D+G Y C
Sbjct: 4128 IHQLEAKDTGEYAC 4141
Score = 32.7 bits (73), Expect = 0.74
Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+ L + + G + L+C + S + W K ++ +Y E C L+I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
+ D+G Y C V G+ L ++A A
Sbjct: 3510 LAMADAGEYLC----VCGQERTSATLTIRALPA 3538
Score = 31.2 bits (69), Expect = 2.2
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G S L C V A + ++ W K+ ++ + K R + + L +++ D+G YTC+
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCE 1331
Query: 456 A 456
A
Sbjct: 1332 A 1332
Score = 31.2 bits (69), Expect = 2.2
Identities = 20/90 (22%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
F + + + + G + L C + ++ + W K ++ +Y + C L+IR
Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
+ D+G Y+C V G+ L V+A
Sbjct: 3598 LAMADTGEYSC----VCGQERTSAMLTVRA 3623
Score = 31.2 bits (69), Expect = 2.2
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 384 FTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRK 443
FT+ L + +T G + L C + S + W K ++ ++ + C L+IR
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRG 3685
Query: 444 PSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
D+G Y C + G+ L V+A
Sbjct: 3686 LVAEDAGEYLC----MCGKERTSAMLTVRA 3711
Score = 31.2 bits (69), Expect = 2.2
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 5/78 (6%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDS---ILFIRSAQRSDSGRY- 244
GE +G P PQ W +G L + + S +L IR+A + D G Y
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Query: 245 -ELTVRVEDLEAKAVIDI 261
EL R+ A A + I
Sbjct: 6182 CELVNRLGSARASAELRI 6199
Score = 30.8 bits (68), Expect = 2.8
Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G + L C V A P+ ++ W K+ ++ + K R + L +++ D+G Y+C+
Sbjct: 1181 GTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCE 1239
Query: 456 A 456
A
Sbjct: 1240 A 1240
Score = 30.4 bits (67), Expect = 3.7
Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G S L C V A + ++ W K+ ++ + K R + L +++ D+G Y+CK
Sbjct: 1549 GTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCK 1607
Query: 456 A 456
A
Sbjct: 1608 A 1608
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/42 (28%), Positives = 21/42 (50%)
Query: 413 IIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTC 454
+ W+K+ + PKY + G L +R + D+G+Y C
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778
Score = 29.3 bits (64), Expect = 8.2
Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCK 455
G S L C V A + ++ W K+ ++ + K R + L +++ D+G Y+C+
Sbjct: 1641 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCE 1699
Query: 456 A 456
A
Sbjct: 1700 A 1700
Score = 29.3 bits (64), Expect = 8.2
Identities = 17/79 (21%), Positives = 30/79 (37%)
Query: 391 HTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSG 450
H T C + + W K +++ KY+ + + L +R D+G
Sbjct: 3987 HQEVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAG 4046
Query: 451 VYTCKAINVLGEASVDCRL 469
YTC + AS+ R+
Sbjct: 4047 DYTCDTGHTQSMASLSVRV 4065
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 64.7 bits (156), Expect = 2e-10
Identities = 69/301 (22%), Positives = 123/301 (40%), Gaps = 21/301 (6%)
Query: 68 EDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVP--VSARPM 125
EDVP P + S+SSV VSW PP + + ++ Y + G+ + P P
Sbjct: 1248 EDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGV-IRKYTIFCSSPGSGQPAPSEYETSPE 1306
Query: 126 MVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYI 185
+ + + +L G ++LL V+AV+SAG G + + + I +AP + T
Sbjct: 1307 QLFYR-IAHLNRGQQYLLWVAAVTSAGRGNSS---EKVTIEPAGKAPAKII--SFGGTVT 1360
Query: 186 RQVGETVNLQIPFQGKPKPQATWTHNGH------ALDSQRVSMRTGDQDSILFIRSAQRS 239
+ V L G P P WT + ++D R+ G L +R+ +
Sbjct: 1361 TPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNG----TLLLRAVKAE 1416
Query: 240 DSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELL 299
DSG Y T ++++LV P P + + + L W P D G + +
Sbjct: 1417 DSGYYTCTATNTGGFDTIIVNLLVQVPPDQP-RLTVSKTSASSITLTWI-PGDNGGSSIR 1474
Query: 300 GYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELA 359
G+++Q + + +W V + + L G Y ++ ++N G + + +
Sbjct: 1475 GFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKT 1534
Query: 360 H 360
H
Sbjct: 1535 H 1535
Score = 52.8 bits (125), Expect = 7e-07
Identities = 78/325 (24%), Positives = 122/325 (37%), Gaps = 54/325 (16%)
Query: 166 RENIEAPKIRVPRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVS 221
R ++ P +P L + ++V G TV L G P P W +G L DS+
Sbjct: 275 RLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTK 334
Query: 222 MRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGC 281
TG L I + DSG Y V A+A ++VI+ P + L
Sbjct: 335 RITG-----LTISDLRTEDSGTYICEVTNTFGSAEATGILMVID----PLHVTL------ 379
Query: 282 NAALQWTPPQ---DTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSF 338
TP + G+T +L + + + T +W Y T + D I S
Sbjct: 380 ------TPKKLKTGIGSTVILSCALTGSPEFTIRW------YRNTELVLPDEAI----SI 423
Query: 339 RVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFS------EAPSFTQPLADHT 392
R S L TSA + +H A K +DF+ P ++
Sbjct: 424 RGLSNETL-LITSA----QKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKV 478
Query: 393 STPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA----LSE-QGVCTLEIRKPSPF 447
PG L C+ + +P P + W + I + +R +S+ + + + P
Sbjct: 479 VNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIR 538
Query: 448 DSGVYTCKAINVLGEASVDCRLEVK 472
D GVY C A N++G A R+ V+
Sbjct: 539 DGGVYRCTARNLVGSAEYQARINVR 563
Score = 39.7 bits (91), Expect = 0.006
Identities = 89/421 (21%), Positives = 149/421 (35%), Gaps = 51/421 (12%)
Query: 74 PLLLTLDDVSSSSVTVSWEPPERLGRLG-LQGYVLELCREGASEWVPVSARPMMVTQQ-- 130
P+ +TL V+S S+ V+W+ P++ + G ++GY + S M T
Sbjct: 1050 PMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSE 1109
Query: 131 --TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQV 188
T+ NL ++ + V A + AG GP + + + P P ++R I
Sbjct: 1110 VYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQP----PENVRALSITSD 1165
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD--SQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
++ P P+ G+ + S V G+ +I R
Sbjct: 1166 VAVISWSEP----PRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFT 1221
Query: 247 TVRVEDLEAKAVID-----ILVIEK----PGPPSSIRLLDVWGCNAALQWTPPQDTGNTE 297
V+ L D +L I+ PGPP+ I+ + + + W PP N
Sbjct: 1222 NYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKP-NGV 1280
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTC--TISDLIIGNSYSFRVFSENLCGLSTSATVT 355
+ Y + + +GQ P I+ L G Y V + G S+
Sbjct: 1281 IRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSE-- 1338
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS-TQLFCSVRASPKPKII 414
+ +P G +AP+ +TP +L C+ P P +
Sbjct: 1339 ---------KVTIEPAG-------KAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVK 1382
Query: 415 WMKNKMEIQ---GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
W K+ + +R + G TL +R DSG YTC A N G ++ L V
Sbjct: 1383 WTKDSEDSAIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLV 1440
Query: 472 K 472
+
Sbjct: 1441 Q 1441
Score = 36.6 bits (83), Expect = 0.051
Identities = 64/298 (21%), Positives = 108/298 (36%), Gaps = 46/298 (15%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL------DSQRVSMRTGDQDSILFIRSAQRSDSG 242
GE +L +G P P TW + + + + +M G S + + Q D G
Sbjct: 482 GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGG 541
Query: 243 RYELTVR--VEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTG-NTELL 299
Y T R V E +A I++ GPPS + ++ +DT N ++
Sbjct: 542 VYRCTARNLVGSAEYQARINVR-----GPPSIRAMRNITAVAG-------RDTLINCRVI 589
Query: 300 GYMVQKADKKTGQWFT----VLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVT 355
GY +W+ + + + L + + E LC S +
Sbjct: 590 GYPYYSI-----KWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLC----SVLIQ 640
Query: 356 KELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP-KII 414
+L+ Q +A K P QP ++ G + C V + P +I
Sbjct: 641 PQLSISQSVHVAVK-----------VPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRIT 689
Query: 415 WMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
W K+ I S++ + +L+I S +G YTC A N S + +L V+
Sbjct: 690 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVR 747
Score = 30.8 bits (68), Expect = 2.8
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNP-KYRALSEQG------VCTLEIRKPSPFD 448
G + L CSV P PK++W K GNP +Y + G +L IR D
Sbjct: 764 GKAGVLNCSVDGYPPPKVMWKHAKG--SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEED 821
Query: 449 SGVYTCKAINVLG-EASVDCRLEVKASA 475
G Y C+A N +G + S L VK A
Sbjct: 822 IGYYLCQASNGVGTDISKSMFLTVKIPA 849
Score = 29.3 bits (64), Expect = 8.2
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 396 GYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR---ALSEQG---VCTLEIRKPSPFDS 449
G++ +L C+ R I W K I + R A + G V TL+++ DS
Sbjct: 863 GHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDS 922
Query: 450 GVYTCKAINVLGE 462
++C AIN GE
Sbjct: 923 VFFSCHAINSYGE 935
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 62.0 bits (149), Expect = 1e-09
Identities = 70/311 (22%), Positives = 116/311 (37%), Gaps = 53/311 (17%)
Query: 177 PRHLRQTYIRQV--GETVNLQIPFQGKPKPQATWTHNGHALDSQ---RVSMRTGDQDSIL 231
PR +++ ++V G V L+ G P P+ W G L + ++ GD +++
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 232 FIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQ 291
I A D+GRY ++ + S L A+ PQ
Sbjct: 331 -IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAM----PQ 385
Query: 292 DTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTS 351
T + + + KTG V++ P + + + SY LC
Sbjct: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQ---PLSVPVQQVHSPTSY--------LC----- 429
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
+P G F P FT+ L + G L C VR +P
Sbjct: 430 -----------------RPDGTTTAYFP--PVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
Query: 412 KIIWMKNKMEIQGNPKYRALSE--------QGVCTLEIRKPSPFDSGVYTCKAINVLGEA 463
++ W + EIQ +P +R L + + +CTL I + P D+G++TC A N G A
Sbjct: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
Query: 464 SVDCRLEVKAS 474
+ +L V ++
Sbjct: 531 TSTAQLVVTSA 541
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRAL-SEQGVCTLE 440
P F Q D T G ++ C V P P + W + ++ + ++ L E GV +L
Sbjct: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH 477
I + D+G+YTC A N G+ S L V A AH
Sbjct: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH 1007
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 2/95 (2%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE--QGVCT 438
AP F L + G C V +PKPKI W K+ +I + + G C+
Sbjct: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
Query: 439 LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
L + D G YT A N G S RL V+A
Sbjct: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQA 870
Score = 45.8 bits (107), Expect = 8e-05
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 378 FSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-V 436
F AP F Q L G L C V +P P++ W E+ P + E G +
Sbjct: 267 FPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDL 326
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
TL I + D+G YTC A N G + + ++ +++
Sbjct: 327 HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 2/101 (1%)
Query: 376 RDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSE-- 433
++ + P F + L + GY +L C V P P+I W K + + ++ +
Sbjct: 1004 KEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDN 1063
Query: 434 QGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
G L I+ + D+G YT A N G S RL+V S
Sbjct: 1064 HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 61.6 bits (148), Expect = 1e-09
Identities = 36/84 (42%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
APSF+ L D G L CSVR +P P+I W+ N IQ R+ E GV L
Sbjct: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 569
Query: 441 IRKPSPFDSGVYTCKAINVLGEAS 464
I+ P D G YTC A N LG+ S
Sbjct: 570 IQDALPEDHGTYTCLAENALGQVS 593
Score = 60.1 bits (144), Expect = 4e-09
Identities = 73/296 (24%), Positives = 115/296 (38%), Gaps = 24/296 (8%)
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ--DSILFIRSAQRSDSGRYELT 247
+TV + G PKP+ W G + Q S+ + L + A+ DSG Y T
Sbjct: 429 QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
Query: 248 VRVEDLEAKAV----IDILVIEKPGPPSSIRLLD---VWGCNAALQWT---PPQDTGNTE 297
+ ++ L + + P S L D + G + LQ + P
Sbjct: 489 ASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG-LSTSATVTK 356
L G +Q A L I D + + ++ +EN G +S SA VT
Sbjct: 549 LNGQPIQYARSTCEAGVAELH--------IQDALPEDHGTYTCLAENALGQVSCSAWVT- 599
Query: 357 ELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWM 416
H +K+ ++ + AP F Q L+D G + V +P P++IW+
Sbjct: 600 --VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
Query: 417 KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
N EIQ + + +L I++ P D+G YTC+A N GE L V+
Sbjct: 658 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 56.6 bits (135), Expect = 5e-08
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-VCTL 439
AP+F Q L D G L C V + P IIW N ++ K+ LS++G +C++
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1155
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I K P D G+Y C A N G+A C++ V + A
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLE 440
P F++ + D G + + C + P P+++W K+ I+ + ++ E G C+L
Sbjct: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
I D YTCKA+N LGEA+ L V+
Sbjct: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/91 (27%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P F L G + C + P+P++ W+K + +Q + + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ D GVYTC +N G+AS+ L ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 52.4 bits (124), Expect = 9e-07
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
+ GE+V L G TW + +S+ + + + S L I +A++ G Y
Sbjct: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L V + +A +++ V++KP PP+ D+ + L W G + + Y ++
Sbjct: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D W L T+ + DL+ + Y FRV + N+ G S
Sbjct: 1370 IWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
+HI K ++ P +EAP+F P + G + + VR P+P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 419 KMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I ++ +G +L I D G YTC+A N G V L V+ S A
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/306 (21%), Positives = 107/306 (34%), Gaps = 35/306 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
G+ LQ +G P P+ TW NG + R + G + L I+ A D G Y
Sbjct: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE--LHIQDALPEDHGTYTCLA 585
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ + V EK S LL V P + T L G K
Sbjct: 586 ENALGQVSCSAWVTVHEKKSSRKSEYLLPV---------APSKPTAPIFLQGLSDLKVMD 636
Query: 309 KTGQWFTVLERYHPTTCTI-----SDLIIGNSYSFR------------VFSENLCGLSTS 351
+ TV +P I +++ + F VF E+ +
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
A + Q +P + F P T++ G S + C++ P P
Sbjct: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV------TASLGQSVLISCAIAGDPFP 750
Query: 412 KIIWMKN-KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
+ W+++ K + + L + V TL ++K P+ +G Y N +GE S L
Sbjct: 751 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLM 810
Query: 471 VKASAA 476
++ S+A
Sbjct: 811 LQNSSA 816
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ P A D+ SSS+T+SW G +Q Y +E+ W ++
Sbjct: 1330 KPDPPA-GTPCA------SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRV 176
T V++L ++ RV A++ G P+ + + E E PK V
Sbjct: 1383 T--CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
Score = 37.4 bits (85), Expect = 0.030
Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 12/107 (11%)
Query: 375 ERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR----- 429
+RD S P F + + C V PKP++ W ++G P R
Sbjct: 408 QRD-SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWF-----LEGTPVRRQEGSI 461
Query: 430 -ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ G L + K DSG Y+C A N G+ S L+V+ A
Sbjct: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA 508
Score = 32.7 bits (73), Expect = 0.74
Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 137 LGDKFLLRVSAVS--SAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNL 194
+GD L+ S +S S P + P+ EAP +P R I++ G T
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPL-----TEAPAFILPP--RNLCIKE-GATAKF 52
Query: 195 QIPFQGKPKPQATWTHNGHALDS-QRVSMRTGDQDSI-LFIRSAQRSDSGRY 244
+ +G P+PQ TW NG + S R + G + + L I + D G+Y
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
Score = 30.4 bits (67), Expect = 3.7
Identities = 26/108 (24%), Positives = 36/108 (33%)
Query: 364 ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
A + KP + P Q D G S +LF V + WMK + +IQ
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 424 GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ + + + L I G YT N LG L V
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
Score = 29.3 bits (64), Expect = 8.2
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ G+P+PQ TW L S RVS+ + +L I + D G Y
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
Query: 248 V 248
V
Sbjct: 235 V 235
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 61.6 bits (148), Expect = 1e-09
Identities = 36/84 (42%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
APSF+ L D G L CSVR +P P+I W+ N IQ R+ E GV L
Sbjct: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 569
Query: 441 IRKPSPFDSGVYTCKAINVLGEAS 464
I+ P D G YTC A N LG+ S
Sbjct: 570 IQDALPEDHGTYTCLAENALGQVS 593
Score = 60.1 bits (144), Expect = 4e-09
Identities = 73/296 (24%), Positives = 115/296 (38%), Gaps = 24/296 (8%)
Query: 190 ETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQ--DSILFIRSAQRSDSGRYELT 247
+TV + G PKP+ W G + Q S+ + L + A+ DSG Y T
Sbjct: 429 QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
Query: 248 VRVEDLEAKAV----IDILVIEKPGPPSSIRLLD---VWGCNAALQWT---PPQDTGNTE 297
+ ++ L + + P S L D + G + LQ + P
Sbjct: 489 ASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
Query: 298 LLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG-LSTSATVTK 356
L G +Q A L I D + + ++ +EN G +S SA VT
Sbjct: 549 LNGQPIQYARSTCEAGVAELH--------IQDALPEDHGTYTCLAENALGQVSCSAWVT- 599
Query: 357 ELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWM 416
H +K+ ++ + AP F Q L+D G + V +P P++IW+
Sbjct: 600 --VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
Query: 417 KNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
N EIQ + + +L I++ P D+G YTC+A N GE L V+
Sbjct: 658 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 56.6 bits (135), Expect = 5e-08
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-VCTL 439
AP+F Q L D G L C V + P IIW N ++ K+ LS++G +C++
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1155
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I K P D G+Y C A N G+A C++ V + A
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLE 440
P F++ + D G + + C + P P+++W K+ I+ + ++ E G C+L
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
I D YTCKA+N LGEA+ L V+
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/91 (27%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P F L G + C + P+P++ W+K + +Q + + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ D GVYTC +N G+AS+ L ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 52.4 bits (124), Expect = 9e-07
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
+ GE+V L G TW + +S+ + + + S L I +A++ G Y
Sbjct: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L V + +A +++ V++KP PP+ D+ + L W G + + Y ++
Sbjct: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D W L T+ + DL+ + Y FRV + N+ G S
Sbjct: 1370 IWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
+HI K ++ P +EAP+F P + G + + VR P+P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 419 KMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I ++ +G +L I D G YTC+A N G V L V+ S A
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/306 (21%), Positives = 107/306 (34%), Gaps = 35/306 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
G+ LQ +G P P+ TW NG + R + G + L I+ A D G Y
Sbjct: 528 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE--LHIQDALPEDHGTYTCLA 585
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ + V EK S LL V P + T L G K
Sbjct: 586 ENALGQVSCSAWVTVHEKKSSRKSEYLLPV---------APSKPTAPIFLQGLSDLKVMD 636
Query: 309 KTGQWFTVLERYHPTTCTI-----SDLIIGNSYSFR------------VFSENLCGLSTS 351
+ TV +P I +++ + F VF E+ +
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
A + Q +P + F P T++ G S + C++ P P
Sbjct: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV------TASLGQSVLISCAIAGDPFP 750
Query: 412 KIIWMKN-KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
+ W+++ K + + L + V TL ++K P+ +G Y N +GE S L
Sbjct: 751 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLM 810
Query: 471 VKASAA 476
++ S+A
Sbjct: 811 LQNSSA 816
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ P A D+ SSS+T+SW G +Q Y +E+ W ++
Sbjct: 1330 KPDPPA-GTPCA------SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRV 176
T V++L ++ RV A++ G P+ + + E E PK V
Sbjct: 1383 T--CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
Score = 37.4 bits (85), Expect = 0.030
Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 12/107 (11%)
Query: 375 ERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYR----- 429
+RD S P F + + C V PKP++ W ++G P R
Sbjct: 408 QRD-SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWF-----LEGTPVRRQEGSI 461
Query: 430 -ALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASA 475
+ G L + K DSG Y+C A N G+ S L+V+ A
Sbjct: 462 EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA 508
Score = 32.7 bits (73), Expect = 0.74
Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 137 LGDKFLLRVSAVS--SAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNL 194
+GD L+ S +S S P + P+ EAP +P R I++ G T
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPL-----TEAPAFILPP--RNLCIKE-GATAKF 52
Query: 195 QIPFQGKPKPQATWTHNGHALDS-QRVSMRTGDQDSI-LFIRSAQRSDSGRY 244
+ +G P+PQ TW NG + S R + G + + L I + D G+Y
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
Score = 30.4 bits (67), Expect = 3.7
Identities = 26/108 (24%), Positives = 36/108 (33%)
Query: 364 ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
A + KP + P Q D G S +LF V + WMK + +IQ
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 424 GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ + + + L I G YT N LG L V
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
Score = 29.3 bits (64), Expect = 8.2
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ G+P+PQ TW L S RVS+ + +L I + D G Y
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
Query: 248 V 248
V
Sbjct: 235 V 235
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 61.6 bits (148), Expect = 1e-09
Identities = 36/84 (42%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
APSF+ L D G L CSVR +P P+I W+ N IQ R+ E GV L
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 500
Query: 441 IRKPSPFDSGVYTCKAINVLGEAS 464
I+ P D G YTC A N LG+ S
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVS 524
Score = 56.6 bits (135), Expect = 5e-08
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-VCTL 439
AP+F Q L D G L C V + P IIW N ++ K+ LS++G +C++
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1086
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I K P D G+Y C A N G+A C++ V + A
Sbjct: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLE 440
P F++ + D G + + C + P P+++W K+ I+ + ++ E G C+L
Sbjct: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
I D YTCKA+N LGEA+ L V+
Sbjct: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/91 (27%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P F L G + C + P+P++ W+K + +Q + + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ D GVYTC +N G+AS+ L ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 4/147 (2%)
Query: 327 ISDLIIGNSYSFRVFSENLCG-LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFT 385
I D + + ++ +EN G +S SA VT H +K+ ++ + AP F
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVT---VHEKKSSRKSEYLLPVAPSKPTAPIFL 557
Query: 386 QPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPS 445
Q L+D G + V +P P++IW+ N EIQ + + +L I++
Sbjct: 558 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 617
Query: 446 PFDSGVYTCKAINVLGEASVDCRLEVK 472
P D+G YTC+A N GE L V+
Sbjct: 618 PEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
Score = 52.4 bits (124), Expect = 9e-07
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
+ GE+V L G TW + +S+ + + + S L I +A++ G Y
Sbjct: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L V + +A +++ V++KP PP+ D+ + L W G + + Y ++
Sbjct: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D W L T+ + DL+ + Y FRV + N+ G S
Sbjct: 1301 IWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
+HI K ++ P +EAP+F P + G + + VR P+P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 419 KMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I ++ +G +L I D G YTC+A N G V L V+ S A
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/306 (21%), Positives = 107/306 (34%), Gaps = 35/306 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
G+ LQ +G P P+ TW NG + R + G + L I+ A D G Y
Sbjct: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE--LHIQDALPEDHGTYTCLA 516
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ + V EK S LL V P + T L G K
Sbjct: 517 ENALGQVSCSAWVTVHEKKSSRKSEYLLPV---------APSKPTAPIFLQGLSDLKVMD 567
Query: 309 KTGQWFTVLERYHPTTCTI-----SDLIIGNSYSFR------------VFSENLCGLSTS 351
+ TV +P I +++ + F VF E+ +
Sbjct: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
A + Q +P + F P T++ G S + C++ P P
Sbjct: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV------TASLGQSVLISCAIAGDPFP 681
Query: 412 KIIWMKN-KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
+ W+++ K + + L + V TL ++K P+ +G Y N +GE S L
Sbjct: 682 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLM 741
Query: 471 VKASAA 476
++ S+A
Sbjct: 742 LQNSSA 747
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ P A D+ SSS+T+SW G +Q Y +E+ W ++
Sbjct: 1261 KPDPPA-GTPCA------SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRV 176
T V++L ++ RV A++ G P+ + + E E PK V
Sbjct: 1314 T--CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
Score = 32.7 bits (73), Expect = 0.74
Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 137 LGDKFLLRVSAVS--SAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNL 194
+GD L+ S +S S P + P+ EAP +P R I++ G T
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPL-----TEAPAFILPP--RNLCIKE-GATAKF 52
Query: 195 QIPFQGKPKPQATWTHNGHALDS-QRVSMRTGDQDSI-LFIRSAQRSDSGRY 244
+ +G P+PQ TW NG + S R + G + + L I + D G+Y
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
Score = 30.4 bits (67), Expect = 3.7
Identities = 26/108 (24%), Positives = 36/108 (33%)
Query: 364 ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
A + KP + P Q D G S +LF V + WMK + +IQ
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 424 GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ + + + L I G YT N LG L V
Sbjct: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
Score = 29.3 bits (64), Expect = 8.2
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ G+P+PQ TW L S RVS+ + +L I + D G Y
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
Query: 248 V 248
V
Sbjct: 235 V 235
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 61.6 bits (148), Expect = 1e-09
Identities = 36/84 (42%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
APSF+ L D G L CSVR +P P+I W+ N IQ R+ E GV L
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 500
Query: 441 IRKPSPFDSGVYTCKAINVLGEAS 464
I+ P D G YTC A N LG+ S
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVS 524
Score = 56.6 bits (135), Expect = 5e-08
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQG-VCTL 439
AP+F Q L D G L C V + P IIW N ++ K+ LS++G +C++
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1086
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I K P D G+Y C A N G+A C++ V + A
Sbjct: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRA-LSEQGVCTLE 440
P F++ + D G + + C + P P+++W K+ I+ + ++ E G C+L
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
I D YTCKA+N LGEA+ L V+
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831
Score = 53.9 bits (128), Expect = 3e-07
Identities = 25/91 (27%), Positives = 43/91 (47%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEI 441
P F L G + C + P+P++ W+K + +Q + + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 442 RKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+ D GVYTC +N G+AS+ L ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 4/147 (2%)
Query: 327 ISDLIIGNSYSFRVFSENLCG-LSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFT 385
I D + + ++ +EN G +S SA VT H +K+ ++ + AP F
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVT---VHEKKSSRKSEYLLPVAPSKPTAPIFL 557
Query: 386 QPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPS 445
Q L+D G + V +P P++IW+ N EIQ + + +L I++
Sbjct: 558 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 617
Query: 446 PFDSGVYTCKAINVLGEASVDCRLEVK 472
P D+G YTC+A N GE L V+
Sbjct: 618 PEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
Score = 52.4 bits (124), Expect = 9e-07
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Query: 187 QVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYE 245
+ GE+V L G TW + +S+ + + + S L I +A++ G Y
Sbjct: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
Query: 246 LTVRVEDLEAKAVIDILVIEKPGPPSSIRLL-DVWGCNAALQWTPPQDTGNTELLGYMVQ 304
L V + +A +++ V++KP PP+ D+ + L W G + + Y ++
Sbjct: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
Query: 305 KADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
D W L T+ + DL+ + Y FRV + N+ G S
Sbjct: 1301 IWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
Score = 50.8 bits (120), Expect = 3e-06
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Query: 359 AHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKN 418
+HI K ++ P +EAP+F P + G + + VR P+P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 419 KMEIQGNPKYRA-LSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
I ++ +G +L I D G YTC+A N G V L V+ S A
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/306 (21%), Positives = 107/306 (34%), Gaps = 35/306 (11%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTV 248
G+ LQ +G P P+ TW NG + R + G + L I+ A D G Y
Sbjct: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE--LHIQDALPEDHGTYTCLA 516
Query: 249 RVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADK 308
+ + V EK S LL V P + T L G K
Sbjct: 517 ENALGQVSCSAWVTVHEKKSSRKSEYLLPV---------APSKPTAPIFLQGLSDLKVMD 567
Query: 309 KTGQWFTVLERYHPTTCTI-----SDLIIGNSYSFR------------VFSENLCGLSTS 351
+ TV +P I +++ + F VF E+ +
Sbjct: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
Query: 352 ATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKP 411
A + Q +P + F P T++ G S + C++ P P
Sbjct: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV------TASLGQSVLISCAIAGDPFP 681
Query: 412 KIIWMKN-KMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLE 470
+ W+++ K + + L + V TL ++K P+ +G Y N +GE S L
Sbjct: 682 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLM 741
Query: 471 VKASAA 476
++ S+A
Sbjct: 742 LQNSSA 747
Score = 39.3 bits (90), Expect = 0.008
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Query: 62 KPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVS 121
KP PP+ P A D+ SSS+T+SW G +Q Y +E+ W ++
Sbjct: 1261 KPDPPA-GTPCA------SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
Query: 122 ARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRV 176
T V++L ++ RV A++ G P+ + + E E PK V
Sbjct: 1314 T--CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
Score = 32.7 bits (73), Expect = 0.74
Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 137 LGDKFLLRVSAVS--SAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNL 194
+GD L+ S +S S P + P+ EAP +P R I++ G T
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPL-----TEAPAFILPP--RNLCIKE-GATAKF 52
Query: 195 QIPFQGKPKPQATWTHNGHALDS-QRVSMRTGDQDSI-LFIRSAQRSDSGRY 244
+ +G P+PQ TW NG + S R + G + + L I + D G+Y
Sbjct: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
Score = 30.4 bits (67), Expect = 3.7
Identities = 26/108 (24%), Positives = 36/108 (33%)
Query: 364 ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
A + KP + P Q D G S +LF V + WMK + +IQ
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 424 GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ + + + L I G YT N LG L V
Sbjct: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
Score = 29.3 bits (64), Expect = 8.2
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHALD-SQRVSMRTGDQDSILFIRSAQRSDSGRYELT 247
G+ G+P+PQ TW L S RVS+ + +L I + D G Y
Sbjct: 175 GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
Query: 248 V 248
V
Sbjct: 235 V 235
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 60.8 bits (146), Expect = 3e-09
Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 382 PSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPK-YRALSEQGVCTLE 440
P+F L D + G + V+ PKP + W++N+ ++ + + + +E G+C L
Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473
I D+G YTCKA+N G + RLEV+A
Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRA 961
Score = 53.9 bits (128), Expect = 3e-07
Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 351 SATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPK 410
SA+V +EL H ++ + P F L D G + L C A P
Sbjct: 2564 SASVQEELGH-----------QYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPA 2612
Query: 411 PKIIWMKNKMEIQGNPKYRALS-EQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRL 469
P I WMK+K ++ P +S + G L I + +G+Y C A NVLG + C +
Sbjct: 2613 PHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTV 2672
Query: 470 EV 471
V
Sbjct: 2673 AV 2674
Score = 52.8 bits (125), Expect = 7e-07
Identities = 74/343 (21%), Positives = 130/343 (37%), Gaps = 26/343 (7%)
Query: 143 LRVSAVSSAGAGPPAMLDQPIHIRENIEA---PKIRVPRHLRQTYIRQVG--ETVNLQIP 197
L V +A +GP + L++ I E E ++ +P LR +VG + L+
Sbjct: 1151 LYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQ 1210
Query: 198 FQGKPKPQATWTHNGHALDSQRVSMRTGDQD-SILFIRSAQRSDSGRYELTVRVEDLEAK 256
G P P +W HNGH + S T +D L + +G Y+ + + +A
Sbjct: 1211 VTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAA 1270
Query: 257 AVIDILVIE-KPGPPSSI-RLLDVWGCNAALQWTPPQDTG---NTELLGYMVQKADKKTG 311
+ V + PGPP +++ V G L W PP+ + + L Y VQ +
Sbjct: 1271 CYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSD 1330
Query: 312 QWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPK 371
QW ++ + L G + FRV S + S + ++ + ++ +
Sbjct: 1331 QWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAP 1390
Query: 372 GFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNK---MEIQGNPKY 428
+++ P + P T F V A +++W + +E +
Sbjct: 1391 AMLDK-----PDIVYVV---EGQPASVTVTFNHVEA----QVVWRSCRGALLEARAGVYE 1438
Query: 429 RALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+ + L I + S D G TC A N G + LE+
Sbjct: 1439 LSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLEL 1481
Score = 52.4 bits (124), Expect = 9e-07
Identities = 28/98 (28%), Positives = 46/98 (46%)
Query: 377 DFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGV 436
+ +EAP F + D G + + V P P I+W K+++ + + + E+
Sbjct: 1480 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE 1539
Query: 437 CTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
C+L + D GVYTC A N+ GE S L V ++
Sbjct: 1540 CSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577
Score = 51.2 bits (121), Expect = 2e-06
Identities = 65/292 (22%), Positives = 104/292 (35%), Gaps = 28/292 (9%)
Query: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
G+ V + I QG+PKP +W N + D +R + L I +A+R D+G Y
Sbjct: 883 GQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTC 942
Query: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDT----GNTELLGYM 302
V + A+ L + S+ +L P QD G L +
Sbjct: 943 KA-VNEYGARQCEARLEVRAHPESRSLAVL-----------APLQDVDVGAGEMALFECL 990
Query: 303 VQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFS--ENLCGLSTSATVTKELAH 360
V W P G + S E+ G+ T T +
Sbjct: 991 VAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDEL 1050
Query: 361 IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKM 420
A + +P S AP FT+ L D G + + C + +P P + W
Sbjct: 1051 TCSARLTVRP--------SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGC 1102
Query: 421 EIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
++ + R + G+ +L I D G+Y A+N G+A +L V+
Sbjct: 1103 PMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/93 (31%), Positives = 45/93 (48%)
Query: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439
EAP F PL + PG L C + A+P P++ W K+ ++ + +E TL
Sbjct: 720 EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTL 779
Query: 440 EIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
+R+ D+G Y A N LG+A+ L V+
Sbjct: 780 LLREARAADAGSYMATATNELGQATCAASLTVR 812
Score = 49.3 bits (116), Expect = 8e-06
Identities = 78/359 (21%), Positives = 125/359 (34%), Gaps = 61/359 (16%)
Query: 167 ENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQ-RVSMRTG 225
E +EAP +P Q + G V L+ P PQ +W +G AL S+ R+ +R
Sbjct: 717 EPLEAPVFEIPL---QNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAE 773
Query: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPG----------------- 268
+ L +R A+ +D+G Y T E +A + V +PG
Sbjct: 774 GERHTLLLREARAADAGSYMATATNELGQATCAASLTV--RPGGSTSPFSSPITSDEEYL 831
Query: 269 -PPSSI-RLLDVWGCNAALQWTPPQ-----DTGNTE-------------------LLGYM 302
PP + W ++ +P Q DTG+ ++
Sbjct: 832 SPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIR 891
Query: 303 VQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL--CGLSTSATVTKELAH 360
VQ K W + P ++ G R+ + G T V + A
Sbjct: 892 VQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGAR 951
Query: 361 IQKA--DIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWM-K 417
+A ++ A P+ S + + PL D G C V ++ W+ +
Sbjct: 952 QCEARLEVRAHPE-------SRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCR 1004
Query: 418 NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAA 476
++ K + + C L + DSGVYTCK E + RL V+ S A
Sbjct: 1005 GRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLA 1063
Score = 38.5 bits (88), Expect = 0.014
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 381 APSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLE 440
AP F +PL + G +L V +P+P + W ++ + A + + C L
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLP------APAPEPSC-LW 94
Query: 441 IRKPSPFDSGVYTCKAINVLGEASVDCRLEV 471
+R+ D+GVY+C A N G AS + L V
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 35.4 bits (80), Expect = 0.11
Identities = 53/218 (24%), Positives = 83/218 (38%), Gaps = 44/218 (20%)
Query: 56 TASTATKPAPPSEDVP---------SAPLLLTLDDV------SSSSVTVSWEPPE-RLGR 99
T +++KP+PPSE V AP +L D+ +SVTV++ E ++
Sbjct: 1363 TVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVW 1422
Query: 100 LGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAML 159
+G +LE R G E ++Q D++ LR+ VS G
Sbjct: 1423 RSCRGALLE-ARAGVYE----------LSQPD------DDQYCLRICRVSRRDMGALTCT 1465
Query: 160 DQPIH-------IRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNG 212
+ H E EAP+ + + GET + +GKP P W +
Sbjct: 1466 ARNRHGTQTCSVTLELAEAPRFE---SIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDE 1522
Query: 213 HAL-DSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVR 249
L +S VS + + L + S D G Y T +
Sbjct: 1523 VLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQ 1560
Score = 33.1 bits (74), Expect = 0.57
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)
Query: 4 KNTSEGPACSPEETASESAKV-PTAEPPGEVAVSESTREEQVPKPQAPAPQ--------- 53
+ E P+ S A S+ P+A P +E + PQ PAPQ
Sbjct: 2159 RRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEP 2218
Query: 54 APTASTATKPAPPSEDVPSAPLLLT 78
P A+KPAPP + + + L LT
Sbjct: 2219 RPEPVRASKPAPPPQALQTLALPLT 2243
Score = 32.3 bits (72), Expect = 0.97
Identities = 28/110 (25%), Positives = 41/110 (37%), Gaps = 22/110 (20%)
Query: 24 VPTAEPPGEVAVSESTREEQV---------PKPQAPAPQAPTASTATKPAPPSEDVPSAP 74
+P + P G VS ST V P+P AP P + P+++V S+P
Sbjct: 2883 IPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPPAPEPPPEPTKVTVQSLSPAKEVVSSP 2942
Query: 75 LLLTLDDVSSSSVTVSWEPPER---------LGRLGLQGYVLELCREGAS 115
T+ PP++ GR G V+ CRE A+
Sbjct: 2943 GSSPRSSPRPEGTTLRQGPPQKPYTFLEEKARGRFG----VVRACRENAT 2988
Score = 30.0 bits (66), Expect = 4.8
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 6 TSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPA- 64
TS P +P S V + PP + + S+ + P PQ P P+ A +PA
Sbjct: 2801 TSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTP-PRRHRGLQAARPAE 2859
Query: 65 ---PPSEDVPSAPLLLTLD 80
P + PS P LD
Sbjct: 2860 PTLPSTHVTPSEPKPFVLD 2878
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,797,509
Number of Sequences: 37866
Number of extensions: 1059464
Number of successful extensions: 13122
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 307
Number of HSP's successfully gapped in prelim test: 488
Number of HSP's that attempted gapping in prelim test: 6307
Number of HSP's gapped (non-prelim): 4924
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.