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Search of human proteins with 55953100
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
(1543 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens] 3138 0.0
gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens] 1374 0.0
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens] 144 7e-34
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens] 144 7e-34
gi|29826279 tubby isoform b [Homo sapiens] 78 8e-14
gi|19923167 tubby isoform a [Homo sapiens] 78 8e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 77 1e-13
gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens] 75 5e-13
gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens] 74 1e-12
gi|157266334 tubby like protein 1 [Homo sapiens] 73 2e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 5e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 69 4e-11
gi|238859545 tubby like protein 2 [Homo sapiens] 68 6e-11
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 58 6e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 57 1e-07
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 56 3e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is... 55 7e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 55 7e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 55 7e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 55 7e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 54 1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 54 1e-06
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 54 2e-06
gi|31543535 R3H domain containing 1 [Homo sapiens] 52 6e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 51 1e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 51 1e-05
gi|16554629 WD repeat domain 5 [Homo sapiens] 50 1e-05
gi|16554627 WD repeat domain 5 [Homo sapiens] 50 1e-05
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 50 1e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 1e-05
>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
Length = 1543
Score = 3138 bits (8137), Expect = 0.0
Identities = 1543/1543 (100%), Positives = 1543/1543 (100%)
Query: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT
Sbjct: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
Query: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL
Sbjct: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
Query: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ
Sbjct: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
Query: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP
Sbjct: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
Query: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA
Sbjct: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
Query: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA
Sbjct: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
Query: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI
Sbjct: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
Query: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL
Sbjct: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
Query: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP
Sbjct: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
Query: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT
Sbjct: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
Query: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP
Sbjct: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
Query: 661 NVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQSLLANQNVQ 720
NVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQSLLANQNVQ
Sbjct: 661 NVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQSLLANQNVQ 720
Query: 721 LDVLTNQTTAVGTAEHAGDSATQYPVSNRYSNPGQVIFGSVEMGRIIQNPPPLSLPPPPQ 780
LDVLTNQTTAVGTAEHAGDSATQYPVSNRYSNPGQVIFGSVEMGRIIQNPPPLSLPPPPQ
Sbjct: 721 LDVLTNQTTAVGTAEHAGDSATQYPVSNRYSNPGQVIFGSVEMGRIIQNPPPLSLPPPPQ 780
Query: 781 GPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGT 840
GPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGT
Sbjct: 781 GPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGT 840
Query: 841 IPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEV 900
IPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEV
Sbjct: 841 IPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEV 900
Query: 901 CRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYSIPTGDPPP 960
CRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYSIPTGDPPP
Sbjct: 901 CRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYSIPTGDPPP 960
Query: 961 YPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPG 1020
YPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPG
Sbjct: 961 YPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPG 1020
Query: 1021 GVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDR 1080
GVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDR
Sbjct: 1021 GVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDR 1080
Query: 1081 TDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTA 1140
TDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTA
Sbjct: 1081 TDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTA 1140
Query: 1141 QTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPL 1200
QTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPL
Sbjct: 1141 QTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPL 1200
Query: 1201 PGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVAL 1260
PGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVAL
Sbjct: 1201 PGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVAL 1260
Query: 1261 HPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPPADLQSHLGTEVMVETADNFQEVLS 1320
HPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPPADLQSHLGTEVMVETADNFQEVLS
Sbjct: 1261 HPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPPADLQSHLGTEVMVETADNFQEVLS 1320
Query: 1321 LTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKEARTLSDFNSLISSPHLGRE 1380
LTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKEARTLSDFNSLISSPHLGRE
Sbjct: 1321 LTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKEARTLSDFNSLISSPHLGRE 1380
Query: 1381 KKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDELMNQSQGSRKGWKSKRSPRAAG 1440
KKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDELMNQSQGSRKGWKSKRSPRAAG
Sbjct: 1381 KKKVKSQKDQLKSKKLNKTNEFQDSSESEPELFISGDELMNQSQGSRKGWKSKRSPRAAG 1440
Query: 1441 ELEEAKCRRASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIE 1500
ELEEAKCRRASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIE
Sbjct: 1441 ELEEAKCRRASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIE 1500
Query: 1501 LEGRQVMQFGRIDGSAYILDFQYPFSAVQAFAVALANVTQRLK 1543
LEGRQVMQFGRIDGSAYILDFQYPFSAVQAFAVALANVTQRLK
Sbjct: 1501 LEGRQVMQFGRIDGSAYILDFQYPFSAVQAFAVALANVTQRLK 1543
>gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]
Length = 678
Score = 1374 bits (3556), Expect = 0.0
Identities = 671/671 (100%), Positives = 671/671 (100%)
Query: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT
Sbjct: 1 MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGVTFT 60
Query: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL
Sbjct: 61 SSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVEL 120
Query: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ
Sbjct: 121 VNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQ 180
Query: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP
Sbjct: 181 QVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPP 240
Query: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA
Sbjct: 241 QDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLA 300
Query: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA
Sbjct: 301 VAGMERQTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMA 360
Query: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI
Sbjct: 361 SGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPI 420
Query: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL
Sbjct: 421 PDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVGGPCYTLYLEYLGGLVPILKGRRISKL 480
Query: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP
Sbjct: 481 RPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSP 540
Query: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT
Sbjct: 541 KLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVT 600
Query: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP
Sbjct: 601 SNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNP 660
Query: 661 NVFSEDEDDLP 671
NVFSEDEDDLP
Sbjct: 661 NVFSEDEDDLP 671
>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
Length = 1170
Score = 144 bits (363), Expect = 7e-34
Identities = 104/364 (28%), Positives = 172/364 (47%), Gaps = 50/364 (13%)
Query: 20 LSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGV----TFTSSHCRRDRSTPQRIN 75
LS K +P + K + V + E+G++A G G++ V T T R + P ++
Sbjct: 5 LSKKISIPNNVKLQCVSWNK--EQGFIACGGEDGLLKVLKLETQTDDAKLRGLAAPSNLS 62
Query: 76 FN--LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRG-AQVSDFT 132
N L GH+ V +V WNE YQKL T D +G I VW+ Y+G W E++N+R + V +
Sbjct: 63 MNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLIIVWMLYKGSWIEEMINNRNKSVVRSMS 122
Query: 133 WSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVI 192
W+ DG + I Y DG V+VGSV G R W ++ Q++ W+ D + +LFG A+G++
Sbjct: 123 WNADGQKICIVYEDGAVIVGSVDGNRIWGKDLK-GIQLSHVTWSADSKVLLFGMANGEIH 181
Query: 193 VMDCHGRMLAHVLLH------ESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPPQDGPAA 246
+ D G + + L + + G+ W + ++ Y P
Sbjct: 182 IYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYH-------------GTEGYVEPD----- 223
Query: 247 YPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMER 306
P L V F +G +M + +D +P +I +G+ V QW G +LAVAG ++
Sbjct: 224 --------CPCLAVCFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHMGSVLAVAGFQK 275
Query: 307 QTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALY 366
+ N +V+FY GEH+ TL + + I ++ W ++ +A +Y
Sbjct: 276 AAMQDKDVN-------IVQFYTPFGEHLGTL-KVPGKEISALSWEGGGLKIALAVDSFIY 327
Query: 367 VVRV 370
+
Sbjct: 328 FANI 331
>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
Length = 1181
Score = 144 bits (363), Expect = 7e-34
Identities = 104/364 (28%), Positives = 172/364 (47%), Gaps = 50/364 (13%)
Query: 20 LSWKGRVPKSEKEKPVCRRRYYEEGWLATGNGRGVVGV----TFTSSHCRRDRSTPQRIN 75
LS K +P + K + V + E+G++A G G++ V T T R + P ++
Sbjct: 5 LSKKISIPNNVKLQCVSWNK--EQGFIACGGEDGLLKVLKLETQTDDAKLRGLAAPSNLS 62
Query: 76 FN--LRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRG-AQVSDFT 132
N L GH+ V +V WNE YQKL T D +G I VW+ Y+G W E++N+R + V +
Sbjct: 63 MNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLIIVWMLYKGSWIEEMINNRNKSVVRSMS 122
Query: 133 WSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVI 192
W+ DG + I Y DG V+VGSV G R W ++ Q++ W+ D + +LFG A+G++
Sbjct: 123 WNADGQKICIVYEDGAVIVGSVDGNRIWGKDLK-GIQLSHVTWSADSKVLLFGMANGEIH 181
Query: 193 VMDCHGRMLAHVLLH------ESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPPQDGPAA 246
+ D G + + L + + G+ W + ++ Y P
Sbjct: 182 IYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYH-------------GTEGYVEPD----- 223
Query: 247 YPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLKEVVAQWCTQGDLLAVAGMER 306
P L V F +G +M + +D +P +I +G+ V QW G +LAVAG ++
Sbjct: 224 --------CPCLAVCFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHMGSVLAVAGFQK 275
Query: 307 QTQLGELPNGPLLKSAMVKFYNVRGEHIFTLDTLVQRPIISICWGHRDSRLLMASGPALY 366
+ N +V+FY GEH+ TL + + I ++ W ++ +A +Y
Sbjct: 276 AAMQDKDVN-------IVQFYTPFGEHLGTL-KVPGKEISALSWEGGGLKIALAVDSFIY 327
Query: 367 VVRV 370
+
Sbjct: 328 FANI 331
>gi|29826279 tubby isoform b [Homo sapiens]
Length = 506
Score = 77.8 bits (190), Expect = 8e-14
Identities = 39/80 (48%), Positives = 53/80 (66%), Gaps = 5/80 (6%)
Query: 1467 MANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQ----VMQFGRIDGSAYILDFQ 1522
+ NK P+WN+ TQ Y L+F GRVTQ S KNFQI + G VMQFGR+ + +D+
Sbjct: 425 LQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQI-IHGNDPDYIVMQFGRVAEDVFTMDYN 483
Query: 1523 YPFSAVQAFAVALANVTQRL 1542
YP A+QAFA+AL++ +L
Sbjct: 484 YPLCALQAFAIALSSFDSKL 503
>gi|19923167 tubby isoform a [Homo sapiens]
Length = 561
Score = 77.8 bits (190), Expect = 8e-14
Identities = 39/80 (48%), Positives = 53/80 (66%), Gaps = 5/80 (6%)
Query: 1467 MANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQ----VMQFGRIDGSAYILDFQ 1522
+ NK P+WN+ TQ Y L+F GRVTQ S KNFQI + G VMQFGR+ + +D+
Sbjct: 480 LQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQI-IHGNDPDYIVMQFGRVAEDVFTMDYN 538
Query: 1523 YPFSAVQAFAVALANVTQRL 1542
YP A+QAFA+AL++ +L
Sbjct: 539 YPLCALQAFAIALSSFDSKL 558
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 77.4 bits (189), Expect = 1e-13
Identities = 180/717 (25%), Positives = 250/717 (34%), Gaps = 128/717 (17%)
Query: 675 ASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGTA 734
ASG E +PP P P+ S +A T+ L Q L + +T A G A
Sbjct: 96 ASGRGERAPPAKNTSP-GPVSSPGRASGTTRPGPLGQK-------GLRISAEETVARGKA 147
Query: 735 EHAGDSATQYPVSNRYSN---PGQVIFGSVEMGRI------IQNPPPLSLP-PPPQGPMQ 784
A + + R ++ PG R + P P + P PP +GP +
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 207
Query: 785 LSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPP----PPYPGT 840
+ +H + S A R A G S T ++ P P GT
Sbjct: 208 SVSSAS---EHSTTEPSPAARRRPS--AGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 841 IPAAPTTAAPPPP-----LPPPQ---PPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFD 892
P AP + P P L PPQ P D G S P + + + D
Sbjct: 263 -PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 893 SSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQ--------------PC 938
++ P + L + P P + +L+ + P P
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP 381
Query: 939 SSATLNRLTVPR-YSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLK 997
S T+ + VP + P+ PP P S L ++ SL TL+ + T+
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSL--------QATTSLGSPTLQATHSFLTMS 433
Query: 998 MAQLADSPRAPLQPLAKSKGGPG-GVVTQLPARPP------PALYTCSQCSGTGPSSQPG 1050
Q S +P +P + P LPA PP PA+ S P
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
Query: 1051 ASLAHTASAS-------PLASQSSY---SLLSPPDS------------ARDRTDYVNSAF 1088
+ +H+ A PL +QSS SL +PP S A ++
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553
Query: 1089 TEDEALSQHCQLEKPLRHPPLP------EAAVTLKRPPPYQWDPMLGEDVW--VPQERTA 1140
T + C PL+ PP P E ++ PPP Q P L +P +
Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP-QAPPALASPPLQGLPSPPLS 612
Query: 1141 QTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATF--QTGYGMGVPY-PGSYNN 1197
+ P P L L L P SP P SP AT Q + V ++
Sbjct: 613 PLATPPPQAPPXLALPP---LQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSP 667
Query: 1198 PPLPGVQAPCSPKDA--LSP--TQFAQQEPAVVLQPLY--------PPSLSYCTLPPMYP 1245
PP P VQAP SP + +SP T +Q P++ PL PP T PP P
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 1246 GSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPK-PHLVVEKPLVSP--PPADL 1299
LQ+PP S A PPM +P T PP+ P L+ PL P PPA L
Sbjct: 728 PPLAAPPLQVPP-------SPPASPPM-SPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Score = 61.2 bits (147), Expect = 7e-09
Identities = 131/554 (23%), Positives = 187/554 (33%), Gaps = 104/554 (18%)
Query: 771 PPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTK 830
PP PP Q P L T+ H S +A P+P + A +Q T
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA-PPSPLALSSLQATTSLGSPTLQATH 427
Query: 831 INPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITT 890
+ P A+ T+ + P PP PP+ L P S QT L
Sbjct: 428 -SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS------LPASPPLQTSL------- 473
Query: 891 FDSSGNVEEVCRPRT----RMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRL 946
S V + P T + L S +++ P SS + T+ + P L
Sbjct: 474 ---SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
Query: 947 TVPRY-SIPTGDPPPY---------PEIASQLAQGRGAAQRSDNSLIHATLRRNNREAT- 995
T P ++P+ PPP P + + Q + L + AT
Sbjct: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
Query: 996 -------LKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQ 1048
L L P PL PLA T P PP Q + P+S
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLA----------TPPPQAPPXLALPPLQAPPSPPASP 640
Query: 1049 PGASLAHTASASP--LASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRH 1106
P + LA + +P LA + SPP S V + F+ + P +
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-----VQAPFSPPASPPVSPSATPPSQA 695
Query: 1107 PPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRL 1166
PP AA L+ PP P + P + + P L V
Sbjct: 696 PP-SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP--------------LQVPPS 740
Query: 1167 PFISPKSPASPTATFQTGYGMGVPYPGSYNNPPL---PGVQAPCSPKDALSPTQFAQQEP 1223
P SP P SP+AT P P PPL P +Q P SP +L + A+ P
Sbjct: 741 PPASP--PMSPSAT---------PPP---RVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 1224 AVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKP 1283
PP + + P +PG + P+S ++ P +P T PP+
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQA-------------PFSPSASLP--MSPLATPPPQA 831
Query: 1284 HLVVEKPLVSPPPA 1297
V+ PL+ PP+
Sbjct: 832 PPVLAAPLLQVPPS 845
Score = 60.5 bits (145), Expect = 1e-08
Identities = 136/579 (23%), Positives = 199/579 (34%), Gaps = 93/579 (16%)
Query: 764 GRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAA--EGDAVVFS 821
G + PP PPPP P L +G A +P + A G + S
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLG---------AAGAVGRKPLAERAGGIGGATIPES 73
Query: 822 APQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQT 881
AP+ P + P A PP P + + P
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP------G 127
Query: 882 PLGYE--RITTFDSSGNVEEVCRPRTRML-------CSQNTYTLPGPGSSATLRLTATEK 932
PLG + RI+ ++ + P+ L S T P P + R TE
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 933 KVPQPCSSATLNRLTV-PRYSIPTGD----PPPYPEIASQLAQGRGAAQRSDNSLIHATL 987
+P+P SA T PR S+ + P P + + G G + + SL +
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 988 RRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSS 1047
++ + A+ +PRAP P S+ P G+ P + P + G
Sbjct: 248 PLSSPARSGPSAR--GTPRAPAHP---SQPKPKGLQALRPPQVTPPRKDAAPALG----- 297
Query: 1048 QPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHP 1107
L+ + A+P S + + PPD+A + + L+ L P P
Sbjct: 298 ----PLSSSPLATPSPSGTKARPVPPPDNA---ATPLPATLPPSPPLATPLPLAPP--SP 348
Query: 1108 PLPEAAVTLKRP--------------PPYQWDPMLG--EDVWVPQERTAQT--SGPNPLK 1149
P + TL P PP Q P L + VP T+ + + P+PL
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Query: 1150 LSSLMLS--------QGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPLP 1201
LSSL + Q H ++ P + S SP+ T P + P P
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD-SPPLQAPLSLPASP 467
Query: 1202 GVQAPCSPKDALSPTQFAQQ-EPAVVLQPLYPPS----LSYCTLPPMYPGSSTC-SSLQL 1255
+Q SP A+SP P L L S LS +PP+ SS SLQ
Sbjct: 468 PLQTSLSP--AVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
Query: 1256 PPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSP 1294
PP +L PP++N PP P PL +P
Sbjct: 526 PPASL-------TTPPLENLPSLAPP-PLQTASAPLTTP 556
Score = 55.5 bits (132), Expect = 4e-07
Identities = 163/699 (23%), Positives = 228/699 (32%), Gaps = 122/699 (17%)
Query: 540 PKLPRISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQV 599
P P ++ +P P A L P P PS PS+T Q QV
Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV 391
Query: 600 TSNIWGTKFKI----VGLAAF-LPTNLGAVIYKT--SLLHLQPRQMTIYLPEVRKISMDY 652
++ + + L++ T+LG+ + S L + PRQ + S+
Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT--------QASLTS 443
Query: 653 INLPVFNPNVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQS 712
+ P P D P+ +P + P T P SS + P Q++ + S
Sbjct: 444 PSRPASTP------PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497
Query: 713 LLANQNVQLDVL----TNQTTAVGTAEHAGDSATQYPVSNRYS-NPGQVIFGSVEMGRII 767
+ ++ T + A + + S T P+ N S P + S +
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557
Query: 768 QNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQ 827
PP P P Q P T + +A P LA+ + S P
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA---PPALASPPLQGLPSPPLSPL 614
Query: 828 VTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPP-----------VDVCLKKGDFSLYPTS 876
T PPP P + P A P PP PP P + V L + FS P S
Sbjct: 615 AT---PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPS 670
Query: 877 VHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQ 936
Q P S P L + P P +S + +AT P
Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPP---SLAAPPLQVPPSPPASPPMSPSAT----PP 723
Query: 937 PCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATL 996
P + P + P PP P + ++ R L L
Sbjct: 724 PQAP--------PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL--------- 766
Query: 997 KMAQLADSPRA--PLQPLAKSKGGPGGVVTQLPARPPPALYTCS-QCSGTGPSSQPGASL 1053
Q+ SP A P+ PLAK P + PPAL T Q + P+S PG
Sbjct: 767 ---QVPPSPPASLPMSPLAKP-----------PPQAPPALATPPLQALPSPPASFPG--- 809
Query: 1054 AHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKP-LRHPPLPEA 1112
A SP AS L +PP A L P L+ PP P A
Sbjct: 810 --QAPFSPSASLPMSPLATPPPQAPP-------------------VLAAPLLQVPPSPPA 848
Query: 1113 AVTLKRPPPYQWDPMLGEDVWV--PQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFIS 1170
+ TL+ P + P G D V P+ A GP P S+ +S
Sbjct: 849 SPTLQAP---RRPPTPGPDTSVSGPRLTLALAPGPPPPP------SRSPSSTLSGPDLAG 899
Query: 1171 PKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSP 1209
S A+ T GY G P G+ +PP A C P
Sbjct: 900 HSSSATSTPEELRGYDSG-PEGGAAASPPPDAELAACHP 937
Score = 50.4 bits (119), Expect = 1e-05
Identities = 93/369 (25%), Positives = 127/369 (34%), Gaps = 71/369 (19%)
Query: 989 RNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGT----- 1043
R + E T+ + ++P+ A S G P P PA+ S+ +GT
Sbjct: 135 RISAEETVARGKATEAPKRS----ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 1044 --GPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLE 1101
PS++P + AS+ S + SP R S L
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 1102 KPLRHPP----LPEAAVTLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQ 1157
P R P P A +P P + V P++ A GP LSS L+
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP----LSSSPLAT 306
Query: 1158 GQHLDVSRLPFISPKSPASPT-ATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSP- 1215
P P + A+P AT + P P + PP P AP S + SP
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA---PPSPS--APPSLQTLPSPP 361
Query: 1216 -TQFAQQEPAVVLQPLY-PPSLSYCTLPPMY-PGSSTCSSLQLPPVAL------------ 1260
T +Q P++ P+ PPSL T+PP+ P S T SLQ PP L
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQ--TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419
Query: 1261 --------------------------HPWSSYSACPPMQNPQGTLPPKPHLVVE-KPLVS 1293
P S+ PP+Q P +LP P L P VS
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL-SLPASPPLQTSLSPAVS 478
Query: 1294 PPPADLQSH 1302
P + L H
Sbjct: 479 PLSSPLTIH 487
>gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens]
Length = 442
Score = 75.1 bits (183), Expect = 5e-13
Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 3/77 (3%)
Query: 1469 NKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQ---VMQFGRIDGSAYILDFQYPF 1525
NK P+WN TQ Y L+F GRVTQ S KNFQI + VMQFGR+ + LD+ YP
Sbjct: 363 NKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPL 422
Query: 1526 SAVQAFAVALANVTQRL 1542
AVQAF + L++ +L
Sbjct: 423 CAVQAFGIGLSSFDSKL 439
>gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]
Length = 501
Score = 73.6 bits (179), Expect = 1e-12
Identities = 37/72 (51%), Positives = 46/72 (63%), Gaps = 3/72 (4%)
Query: 1469 NKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQ---VMQFGRIDGSAYILDFQYPF 1525
NK P+WN TQ Y L+F GRVTQ S KNFQI + VMQFGR+ + LD+ YP
Sbjct: 363 NKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPL 422
Query: 1526 SAVQAFAVALAN 1537
AVQAF + L++
Sbjct: 423 CAVQAFGIGLSS 434
>gi|157266334 tubby like protein 1 [Homo sapiens]
Length = 542
Score = 72.8 bits (177), Expect = 2e-12
Identities = 37/77 (48%), Positives = 52/77 (67%), Gaps = 3/77 (3%)
Query: 1469 NKQPLWNEATQVYQLDFGGRVTQESAKNFQI---ELEGRQVMQFGRIDGSAYILDFQYPF 1525
NK P+WN+ + Y L+F GRVTQ S KNFQI + V+QFGR+ A+ LD++YP
Sbjct: 463 NKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAEDAFTLDYRYPL 522
Query: 1526 SAVQAFAVALANVTQRL 1542
A+QAFA+AL++ +L
Sbjct: 523 CALQAFAIALSSFDGKL 539
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 71.6 bits (174), Expect = 5e-12
Identities = 146/585 (24%), Positives = 203/585 (34%), Gaps = 99/585 (16%)
Query: 764 GRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAE--GDAVVFS 821
G + PP PPPP P L +G A +P + A G + S
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAA---------GAVGRKPLAERAGGIGGATIPES 73
Query: 822 APQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQT 881
AP+ P + P A PP P + + P
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG------ 127
Query: 882 PLGYE--RITTFDSSGNVEEVCRPRTRMLC-------SQNTYTLPGPGSSATLRLTATEK 932
PLG + RI+ ++ + P+ L S T P P + R TE
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 933 KVPQPCSSATLNRLTV-PRYSIPTGDP----PPYPEIASQLAQGRGAAQRSDNSLIHATL 987
+P+P SA T PR S+ + P P + + G G + + SL +
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 988 RRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSS 1047
++ + A+ +PRAP P S+ P G+ P + P + G SS
Sbjct: 248 PLSSPARSGPSAR--GTPRAPAHP---SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 1048 QPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLR-- 1105
LA + ++ L SQ+ +L + P S+ S CQL PL
Sbjct: 303 P----LATPSPSAALQSQAPPTLPATPHSS-----------------SLTCQLATPLPLA 341
Query: 1106 --HPPLPEAAVTLKRPP---PYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQH 1160
P P + TL PP P Q LG P + + P+P LS L Q
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGS----PTLQATHSFLPSP-PLSPLATPPPQA 396
Query: 1161 LDVSRLPFIS--PKSPASP------TATFQTGYGMGVPY-PGSYNNPPLPGVQAPCSPKD 1211
LP + P PASP T + Q + V ++ PP P VQAP SP
Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456
Query: 1212 A--LSP--TQFAQQEPAVVLQPLY--------PPSLSYCTLPPMYPGSSTCSSLQL---- 1255
+ +SP T +Q P++ PL PP T PP P LQL
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Query: 1256 ---PPVALHPWSSYSACPPMQNP-QGTLPPKPHLVVEKPLVSPPP 1296
PP P PP P Q P L + PL +PPP
Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM-SPLATPPP 560
Score = 51.2 bits (121), Expect = 8e-06
Identities = 99/399 (24%), Positives = 126/399 (31%), Gaps = 72/399 (18%)
Query: 767 IQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSA---- 822
+ P PL+ PP P P L T+ S A P+ + G + +
Sbjct: 334 LATPLPLA-PPSPSAPPSLQTL-----------PSPPATPPSQATTSLGSPTLQATHSFL 381
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPP-----------VDVCLKKGDFS 871
P PPP P + P A P PP PP P + V L + FS
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 872 LYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTAT- 930
P S Q P S P L + P P +S + +AT
Sbjct: 442 -PPPSPPVQAPFSPPASPPVSPSATPPSQAPP---SLAAPPLQVPPSPPASPPMSPSATP 497
Query: 931 EKKVPQPCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRN 990
+ P P ++ L P + P PP + S A G A S +
Sbjct: 498 PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS---------- 547
Query: 991 NREATLKMAQLADSP-------RAPLQPLAKSKGGPGGVVTQLPARPP-PALYT------ 1036
A+L M+ LA P APL + S P Q P RPP P T
Sbjct: 548 ---ASLPMSPLATPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRRPPTPGPDTSVSGPR 602
Query: 1037 CSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQ 1096
+ GP P S + T S LA SS S S P+ R +S A S
Sbjct: 603 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSS-SATSTPEELRG----YDSGPEGGAAASP 657
Query: 1097 HCQLEKPLRHP------PLPEAAVTLKRPPPYQWDPMLG 1129
E HP P P A P W P G
Sbjct: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 696
Score = 42.0 bits (97), Expect = 0.005
Identities = 83/333 (24%), Positives = 119/333 (35%), Gaps = 54/333 (16%)
Query: 1010 QPLAKSKGGPGGVVTQLPARPPPALYTCSQ-CSGTGPSSQPGASLAHTASASPLASQSSY 1068
+PLA+ GG GG +P P A T S S P+S+P AS +P A +S
Sbjct: 56 KPLAERAGGIGGAT--IPESAPRAGPTRSAGTSSRNPASRPPAS--GRGERAPPAKNTSP 111
Query: 1069 SLLSPPDSARDRT-----DYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQ 1123
+S P A T + +E +++ E P R A P P
Sbjct: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171
Query: 1124 WDPML-------GEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPAS 1176
P + G +V +P R A ++ P P ++G VS S P S
Sbjct: 172 PSPAMARRSRAAGTEVGLP--RPAPSARPRPP-------TEGPRKSVSSASEHSTTEP-S 221
Query: 1177 PTATFQTGYGMGVPYPGS---------YNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVL 1227
P A + G G+ P S ++P G A +P+ +P +Q +P L
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR---APAHPSQPKPKG-L 277
Query: 1228 QPLYPPSLS------------YCTLPPMYPGSSTCSSLQLPP-VALHPWSSYSACPPMQN 1274
Q L PP ++ + P P S Q PP + P SS C +
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ-LAT 336
Query: 1275 PQGTLPPKPHLVVEKPLVSPPPADLQSHLGTEV 1307
P PP P + PPA S T +
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 68.9 bits (167), Expect = 4e-11
Identities = 128/555 (23%), Positives = 191/555 (34%), Gaps = 61/555 (10%)
Query: 764 GRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAE-GDAVVFSA 822
G + PP PPPP P L +G A +P + A G A + +
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAA---------GAVGRKPLAERAGGIGGATIPES 73
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTP 882
T+ + PP A P P P+ P + G + +
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT-RPGPLGQKGLRISAEET 132
Query: 883 LGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSAT 942
+ + T + R T S T P P + R TE +P+P SA
Sbjct: 133 VARGKATEAPKRSALSAGARRDT----SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188
Query: 943 LNRLTV-PRYSIPTGDP----PPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLK 997
T PR S+ + P P + + G G + + SL + ++ +
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248
Query: 998 MAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTA 1057
A+ +PRAP P S+ P G+ P + P + G SS P A+ + +A
Sbjct: 249 SAR--GTPRAPAHP---SQPKPKGLQALRPPQVTPPRKDAAPALGP-LSSSPLATPSPSA 302
Query: 1058 SASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHP---PLPEAAV 1114
SP A S +L SPP + + ++ + H L P P P P+A
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQA---TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 1115 TLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVS-RLPFISPKS 1173
L PP Q P + T PN L + L + PF P S
Sbjct: 360 ALALPP-LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418
Query: 1174 P-ASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKD----------ALSPTQFAQQE 1222
P SP+AT + + P PP P P SP A P Q A+
Sbjct: 419 PPVSPSATPPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477
Query: 1223 PAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPK 1282
P PP + + P +PG + P+S ++ P +P T PP+
Sbjct: 478 PQAPPALATPPLQALPSPPASFPGQA-------------PFSPSASLP--MSPLATPPPQ 522
Query: 1283 PHLVVEKPLVSPPPA 1297
V+ PL+ PP+
Sbjct: 523 APPVLAAPLLQVPPS 537
Score = 52.0 bits (123), Expect = 4e-06
Identities = 107/451 (23%), Positives = 144/451 (31%), Gaps = 71/451 (15%)
Query: 724 LTNQTTAVGTAEHAGDSATQYPVSNRYSNPGQVIFGSVEMGRIIQNPPPLSLPPPPQGPM 783
L++ T + + +G SA P + ++P Q ++ R Q PP P GP+
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 290
Query: 784 QLSTVGHGDRDHEHLQKSAKALR--PTPQLAAEGDAVVFSAPQEVQVTK----------- 830
S + + +L+ P+P A +Q T
Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350
Query: 831 INPPPPYPGTIPAAPTTAAPPPPLPPPQPP-----------VDVCLKKGDFSLYPTSVHY 879
PPP P + P A P PP PP P + V L + FS P S
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPV 409
Query: 880 QTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTAT-EKKVPQPC 938
Q P S P L + P P +S + +AT + P P
Sbjct: 410 QAPFSPPASPPVSPSATPPSQAPP---SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 939 SSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKM 998
++ L P + P PP + S A G A S + A+L M
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS-------------ASLPM 513
Query: 999 AQLADSP-------RAPLQPLAKSKGGPGGVVTQLPARPP-PALYT------CSQCSGTG 1044
+ LA P APL + S P Q P RPP P T + G
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571
Query: 1045 PSSQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPL 1104
P P S + T S LA SS S S P+ R +S A S E
Sbjct: 572 PPPPPSRSPSSTLSGPDLAGHSS-SATSTPEELRG----YDSGPEGGAAASPPPDAELAA 626
Query: 1105 RHP------PLPEAAVTLKRPPPYQWDPMLG 1129
HP P P A P W P G
Sbjct: 627 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657
>gi|238859545 tubby like protein 2 [Homo sapiens]
Length = 520
Score = 68.2 bits (165), Expect = 6e-11
Identities = 33/82 (40%), Positives = 53/82 (64%), Gaps = 3/82 (3%)
Query: 1459 GSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQI---ELEGRQVMQFGRIDGS 1515
G + + ++ NK P W++ VY L+F GRVT+ S KNFQI + + V+QFGR+
Sbjct: 437 GDKQGLLLLHNKTPSWDKENGVYTLNFHGRVTRASVKNFQIVDPKHQEHLVLQFGRVGPD 496
Query: 1516 AYILDFQYPFSAVQAFAVALAN 1537
+ +DF +PFS +QAF++ L++
Sbjct: 497 TFTMDFCFPFSPLQAFSICLSS 518
Score = 34.3 bits (77), Expect = 0.96
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 13/63 (20%)
Query: 594 NYLAQVTSNIWGTKFKI------------VGLAAFLPTNLGAVIYKTSLL-HLQPRQMTI 640
N++ +V SN++ TKF I A + LGAV Y+ ++L +L PR+MT+
Sbjct: 348 NFVGKVRSNVFSTKFTIFDNGVNPDREHLTRNTARIRQELGAVCYEPNVLGYLGPRKMTV 407
Query: 641 YLP 643
LP
Sbjct: 408 ILP 410
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 58.2 bits (139), Expect = 6e-08
Identities = 89/363 (24%), Positives = 129/363 (35%), Gaps = 74/363 (20%)
Query: 954 PTGDPPPYPEIASQLAQGRGAAQRSD---NSLIHATLRRNNREATLKMAQLADSPRAPLQ 1010
P G PPP P A ++ + +R+D S + A +++ R K+ Q+ D ++
Sbjct: 17 PLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR--LRKVTQINDRSAPQIE 74
Query: 1011 -PLAKSKGGPGGVVTQLPARPP----------PALYTCSQCSGTGPSSQPGASLAHTASA 1059
+K G G T+ + PP P L Q G + G A +
Sbjct: 75 SSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG--GKTGQGPGSRAPS 132
Query: 1060 SPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRP 1119
L +++ L PP S R N++ A + + P PP P P
Sbjct: 133 PRLPNKTISGPLIPPASPR----LGNTSEAHGAARTAPPRPNVPAPPPPTPP-------P 181
Query: 1120 PPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTA 1179
PP P L + +T S P PL + LP ++P P +P
Sbjct: 182 PPPPLPPPLPSSSPI---KTPLVSPPGPLTKGN-------------LPVVAPPVPCAPP- 224
Query: 1180 TFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCT 1239
P P PP P P P LS Q + L P+ PP
Sbjct: 225 ----------PPP-----PPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPP---LPL 266
Query: 1240 LPPM-YPG-----SSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVS 1293
LPP YPG +S Q PP P Y++C +P+ +LP P V +
Sbjct: 267 LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASC----SPRASLPAPPLPGVNSSSET 322
Query: 1294 PPP 1296
PPP
Sbjct: 323 PPP 325
Score = 42.0 bits (97), Expect = 0.005
Identities = 30/98 (30%), Positives = 36/98 (36%), Gaps = 26/98 (26%)
Query: 770 PPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVT 829
PPP PPPP P L S+ ++ TP ++ G + P
Sbjct: 175 PPPTPPPPPPPLPPPLP--------------SSSPIK-TPLVSPPGPLTKGNLPVVAPPV 219
Query: 830 KINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKK 867
PPPP P PPPP PPP PP V K
Sbjct: 220 PCAPPPPPP-----------PPPPTPPPLPPASVLSDK 246
Score = 38.5 bits (88), Expect = 0.051
Identities = 106/454 (23%), Positives = 140/454 (30%), Gaps = 107/454 (23%)
Query: 833 PPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFD 892
PPPP P P P APPPP PP PPV S +S+ P G +
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPP-PPSAPPV---------STDTSSLRRADPKGRSALLADI 53
Query: 893 SSGNVEEVCRPRTRMLCSQNTYTLPG-PGSSATLRLTATEKKVPQPCSSATLNRLTVPRY 951
G R R + N + P S T + + TL L +
Sbjct: 54 QQGT-------RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGF 106
Query: 952 SIPTGDPPPYPEIA-SQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQ 1010
P P ++A + QG G+ S R N+ + + A SPR
Sbjct: 107 --PVLRPAGQRDVAGGKTGQGPGSRAPSP--------RLPNKTISGPLIPPA-SPRLGNT 155
Query: 1011 PLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSL 1070
A +PA PPP P P S+SP+ + L
Sbjct: 156 SEAHGAARTAPPRPNVPAPPPPT-----------PPPPPPPLPPPLPSSSPIKT----PL 200
Query: 1071 LSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGE 1130
+SPP T+ P+ PP+P A PPP
Sbjct: 201 VSPP-----------GPLTKGNL---------PVVAPPVPCAPPPPPPPPP--------- 231
Query: 1131 DVWVPQERTAQTSGPNPLKLSSLMLSQG--QHLDVSRLPFISPKSPASPTATFQTGYGMG 1188
P PL +S++ + L LP I P P P
Sbjct: 232 ------------PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPC--------- 270
Query: 1189 VPYPGSYNNP--PLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPG 1246
YPG P P Q P +P L P ++ PL + S T PP+ P
Sbjct: 271 -GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPK 329
Query: 1247 SSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLP 1280
S S Q PP + A P P G+ P
Sbjct: 330 S---PSFQAPPQK----AGAQALPAPPAPPGSQP 356
Score = 37.7 bits (86), Expect = 0.087
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 15/106 (14%)
Query: 770 PPPLSLPPPPQGPMQLSTVGHGDRDHE------HLQKSAKALRPTPQLAAEGDAVVFSAP 823
PPP PPPP P D+ + HL L P G ++P
Sbjct: 223 PPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASP 282
Query: 824 QEVQVTKINPPPPYPGTIPAAPTTAAPPPPL---------PPPQPP 860
+ PPPP P +P + P PPL PPP PP
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP 328
Score = 37.4 bits (85), Expect = 0.11
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 31/133 (23%)
Query: 751 SNPGQVIFGSVEMGRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQ 810
S PG + G++ ++ P P + PPPP P P P
Sbjct: 202 SPPGPLTKGNLP---VVAPPVPCAPPPPPPPPPPTPP-------------------PLPP 239
Query: 811 LAAEGDAVVFSAPQEVQVTKINPPPP------YPG--TIPAAPTTAAPPPPLPPPQ-PPV 861
+ D V + + I PP P YPG PA+P A PP PPP PP
Sbjct: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY 299
Query: 862 DVCLKKGDFSLYP 874
C + P
Sbjct: 300 ASCSPRASLPAPP 312
Score = 32.0 bits (71), Expect = 4.8
Identities = 11/17 (64%), Positives = 12/17 (70%)
Query: 845 PTTAAPPPPLPPPQPPV 861
P PPPPLPPP PP+
Sbjct: 2 PVPPPPPPPLPPPPPPL 18
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 57.0 bits (136), Expect = 1e-07
Identities = 137/602 (22%), Positives = 208/602 (34%), Gaps = 95/602 (15%)
Query: 765 RIIQNPPP-LSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVV---F 820
+++ +P P +S P P+ +S+ H S + + LA+ + V
Sbjct: 1376 KLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPL 1435
Query: 821 SAPQEVQV-TKINPPPPYPGTIP-AAPTTAAPPPP-----LPPPQPPVDVCLKKGDFSLY 873
S+ + V T + P P TIP +AP T + P + PP PV V G SL
Sbjct: 1436 SSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPV-VPAAPGPPSLA 1494
Query: 874 PTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKK 933
P+ +P ++ ++ P +L + + +PG S+
Sbjct: 1495 PSGA---SPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVA--------- 1542
Query: 934 VPQPCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNRE 993
P S L + P+ P P P AS LA A+Q L
Sbjct: 1543 ---PACSPVLVPASALASPFPSA-PNPAPAQASLLAPASSASQALATPLAPM-------- 1590
Query: 994 ATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASL 1053
A + A LA SP PL PL PG ++ P + PSS PG SL
Sbjct: 1591 AAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPV--------MAPSSTPGTSL 1642
Query: 1054 AHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHP-PLPEA 1112
ASASP+ + + +L+P S L P+ P P P +
Sbjct: 1643 ---ASASPVPAPT--PVLAPS--------------------STQTMLPAPVPSPLPSPAS 1677
Query: 1113 AVTLKRPPPYQWDPMLGEDVWVPQER----TAQTSGPNPLKLSSLMLSQGQHLDVSRLPF 1168
TL P P LG P + T GP P + SL + ++
Sbjct: 1678 TQTLALAPALA--PTLGGS--SPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLS 1733
Query: 1169 ISPKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQ 1228
++P P PT T PPL +P P A + T A +L
Sbjct: 1734 LAPGPPLGPTQTLSLAPA-----------PPL-APASPVGPAPAHTLTLAPASSSASLLA 1781
Query: 1229 PLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVE 1288
P +L+ P G + +L L P + +S A + + G P +V
Sbjct: 1782 PASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPAS-QASSLVVSASGAAPLPVTMVSR 1840
Query: 1289 KPLVSPPPADLQSHLGTEVMVETADNFQEVLSLTESPVPQRT----EKFGKKNRKRLDSR 1344
P+ P L G TA +F + P P R+ + +K +++ R
Sbjct: 1841 LPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSER 1900
Query: 1345 AE 1346
E
Sbjct: 1901 LE 1902
Score = 48.5 bits (114), Expect = 5e-05
Identities = 129/583 (22%), Positives = 197/583 (33%), Gaps = 91/583 (15%)
Query: 804 ALRPTPQLAAEGDAVVFSAPQEVQVTKINP---PPPYP---------GTIPAAPTTAAPP 851
+L+PTP + AP + + P PP Y T A TT A P
Sbjct: 1105 SLKPTPPAPVR----LSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVP 1160
Query: 852 PPLPPPQ-----PPVDVCLKKGD-FSLYPTSVHYQTPL---GYERITTFDSSGNVEEVCR 902
P P PQ P + L G+ S+ + Q P+ G + TF GN +
Sbjct: 1161 APTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTG 1220
Query: 903 PRTRMLC-------SQNTYTLPGPGSS-------ATLRLTATEKKVPQPCSSATLNRLTV 948
+ R L +N L G A + L P P + L T
Sbjct: 1221 AQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTP 1280
Query: 949 PRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAP 1008
PTG P A+Q+ ++ ++ +R+ R+ + LA +PR P
Sbjct: 1281 STTPAPTG--LSLPLAANQVP----PTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPP 1334
Query: 1009 LQPLAKSKGGPGGV---VTQLPAR-PPPALYTCSQCSGTGPSSQPGASLAHTASASPLAS 1064
S G P + T P R P P L T T +P L H+ S AS
Sbjct: 1335 ------SSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS 1388
Query: 1065 QSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQW 1124
+ L+ +V S+ + PL P +V L P
Sbjct: 1389 APGAAPLTISSPL-----HVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP--- 1440
Query: 1125 DPMLGEDVWVPQERTAQTSGPNPLKLSS--LMLSQGQHLDVSRLPFISPKSPASP----- 1177
+ VP A S P + +S+ + + G L S P ++P PA+P
Sbjct: 1441 -------ISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSL 1493
Query: 1178 ----TATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPP 1233
+ + +G+ S ++ PG +P + P + PA P+ P
Sbjct: 1494 APSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPA--CSPVLVP 1551
Query: 1234 SLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTL------PPKPHLVV 1287
+ + + P P + + L P + + + PM PQ + PP L V
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPV 1611
Query: 1288 EKPLVSPPPADLQSHLGTEVMVETADNFQEVLSLTESPVPQRT 1330
P SP A + + T V V + + SPVP T
Sbjct: 1612 LAP--SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPT 1652
Score = 45.8 bits (107), Expect = 3e-04
Identities = 131/566 (23%), Positives = 195/566 (34%), Gaps = 109/566 (19%)
Query: 776 PPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPP 835
PPP P+++ K + L+P P+ VV + + + PPP
Sbjct: 983 PPPRPKPVKM--------------KVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPP 1028
Query: 836 -------PYPGTIPAA-----------------PTTAAPPPPLPPPQPPVDVCLKK---- 867
P PG +P P + P P L PP P L +
Sbjct: 1029 GPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPS 1088
Query: 868 --GDFS-----LYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPG 920
G S PT TP R++ G+ + +P L YT P
Sbjct: 1089 PLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGS-SSLLKP----LTVPPGYTFPPAA 1143
Query: 921 SSATLRLTATEKKVPQPCSSATLNRLTVP---RYSIPTGDPPPYPEIASQLAQGRGAAQR 977
++ T TAT P + RL + + +P+G+ ++AS LAQ R A
Sbjct: 1144 ATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLAS-LAQ-RPVANA 1201
Query: 978 SDNSLIHATLRRNNREAT-LKMAQLADSPRAPLQPLA---KSKGGPGGVVTQLPAR---- 1029
+ + ++ N T ++ QLA PLQ S GG +++Q PA
Sbjct: 1202 GGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQ-PAHVALI 1260
Query: 1030 ----PPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVN 1085
P P S PSS P + A T + PLA+ P + + T V
Sbjct: 1261 QAVAPTPGPTPVSVL----PSSTPSTTPAPTGLSLPLAAN------QVPPTMVNNTGVVK 1310
Query: 1086 SAFTE--DEALSQHCQLEKPLRHPPLPEAAVTLKRP---PPYQWDPMLGEDVWVPQERTA 1140
+ + L+ L R P AV RP P P LG TA
Sbjct: 1311 IVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLG---------TA 1361
Query: 1141 QTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNP-P 1199
+ P P + L+ L S P +S +P + T + + PG ++P P
Sbjct: 1362 RAPMPTPTLVRPLL-----KLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMP 1416
Query: 1200 LPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQL---- 1255
+P SP + + P V L P+ + T+P P + + S L
Sbjct: 1417 IPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSV 1476
Query: 1256 -PPVALHPWSSYSACPPMQNPQGTLP 1280
PP+A P + PP P G P
Sbjct: 1477 TPPLA--PVVPAAPGPPSLAPSGASP 1500
Score = 40.0 bits (92), Expect = 0.017
Identities = 56/204 (27%), Positives = 74/204 (36%), Gaps = 43/204 (21%)
Query: 796 EHLQKSAKALRPTPQLAAEG----------DAVVFSAPQEVQVTKIN--PPPPYPGTIPA 843
E + + A RPTP A V SAP + + ++ P PP P IP
Sbjct: 2434 ERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPP 2493
Query: 844 APTTAAPPPP--LPPP---QPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVE 898
+ A PPP PPP PP CL + P+S LG + S N+
Sbjct: 2494 CSSPACTPPPACTPPPAHTPPPAQTCL------VTPSS---PLLLGPPSVPISASVTNLP 2544
Query: 899 EVCRPRTRM----LCSQNTYTLPGPGSSATLRLTATEKK--VP-----QPCSSATLN--- 944
RP + L S + L SS T L+ K +P P S L+
Sbjct: 2545 LGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTP 2604
Query: 945 ---RLTVPRYSIPTGDPPPYPEIA 965
LT+ SIP G P+ A
Sbjct: 2605 SAPSLTLEAGSIPNGQEQEAPDSA 2628
Score = 31.6 bits (70), Expect = 6.2
Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 18/161 (11%)
Query: 699 QAMSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGTAEHAGDSATQYPVSNRYSNPGQVIF 758
+A +PT S Q L V +V T++ T+ G S + P R V
Sbjct: 2679 EAKTPTSSPEKPQEL-----VTAEVAAPSTSSSATSSPEGPSPARPP---RRRTSADVEI 2730
Query: 759 GSVEMGRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAV 818
GR Q P P L P +L TV + + L + + R G +
Sbjct: 2731 RGQGTGRPGQPPGPKVLRKLPG---RLVTVV----EEKELVRRRRQQRGAASTLVPGVSE 2783
Query: 819 VFSAPQEVQVTKINPP---PPYPGTIPAAPTTAAPPPPLPP 856
++P V ++ P PP G AAP+++ P PP P
Sbjct: 2784 TSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQP 2824
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 55.8 bits (133), Expect = 3e-07
Identities = 166/751 (22%), Positives = 238/751 (31%), Gaps = 140/751 (18%)
Query: 671 PVTGASGVPENSP--PCTVNIPIAPIHSSAQ-------------------------AMSP 703
P+ G G+P SP + +API Q A P
Sbjct: 210 PIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAGP 269
Query: 704 TQSIGLVQSLLANQNVQLDVLTNQTTAV-----GTAEHAGDSATQYPVSNRYSNPGQVIF 758
++ + L + ++ Q L + N + AV G + G A P P V
Sbjct: 270 SEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAP 329
Query: 759 GS-----VEMGRIIQNPPPLSLPPPPQGPM-----QLSTVGHGDRDHE-HLQKSAKALRP 807
G V +I + P + P P G + QL+ +Q AL
Sbjct: 330 GLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQ 389
Query: 808 TPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTI----PAAPTTAAPPPPLPPPQPPVDV 863
P+ + + V P P + PA T AAPP P P+ V
Sbjct: 390 QPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSV 449
Query: 864 CLKKGDFS---------------LYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTR-- 906
L S L P + Q P + + G + P T
Sbjct: 450 HLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPA-NVGGQILAAAAPHTGGQ 508
Query: 907 -----MLCSQNT--------YTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYSI 953
+L +QN P G+ + L+A +V QP +++ S+
Sbjct: 509 LIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM--PVSLAAGSL 566
Query: 954 PT-GDPPPYPEIASQLAQG------RGAAQRSDNSLIHATLRRNNREATLKMAQLADSPR 1006
PT P P A+ + QG A + + L+ AT + A +
Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPA---TPAAATGEAAPVLTVQP 623
Query: 1007 APLQPLAKSKGGPGGVVTQLPARPP--PALYTCSQCSGTGPSSQPGASLAHTASASPLAS 1064
AP P A S P G+ +PP P + T P PG LAS
Sbjct: 624 APQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPG-----------LAS 672
Query: 1065 QSSYSLLSPPDSARDRTDYVNSA---FTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPP 1121
+L P SA + F E Q E P H +P A+V + PPP
Sbjct: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP--HLSVP-ASVIVSAPPP 729
Query: 1122 YQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATF 1181
Q DP P A+ +G P S + P P +SP+
Sbjct: 730 AQ-DP-------APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 1182 QTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLP 1241
Q G P + P P + P P+ P EP L P PP P
Sbjct: 782 QAPLGDSPHLPSPH--PTRPPSRPPSRPQSVSRPPS----EPP--LHPCPPPQA-----P 828
Query: 1242 PMYPGSSTCSS-LQLPPVALHPWSSYSACPP------MQNPQGTLPPKPHLVVEKPLVSP 1294
P PG + L +PP A +P + P Q P+G LPP PHL P +
Sbjct: 829 PTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL---PPSSTS 885
Query: 1295 PPADLQSHLGTEVMVETADNFQEVLSLTESP 1325
S + + T +FQ ++ P
Sbjct: 886 SAVASSSETSSRLPAPTPSDFQLQFPPSQGP 916
Score = 38.1 bits (87), Expect = 0.066
Identities = 62/247 (25%), Positives = 82/247 (33%), Gaps = 42/247 (17%)
Query: 833 PPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFD 892
PPPP PA A PPP PPP PP G P + + PLG
Sbjct: 1333 PPPP-----PATLKVAEPPPRPPPPPPPTG--QMNGTVDHPPPAAPERKPLG-------- 1377
Query: 893 SSGNVEEVCRPRTRMLCSQNTY--TLPGPGSSATLRLTATEKKVPQP-------CSSATL 943
P L + TY + GPG+ P P +S +
Sbjct: 1378 --------TAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI 1429
Query: 944 NRLTVPR---YSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQ 1000
L Y PPP P A+ AQG G L A R++ + +
Sbjct: 1430 RELAAVEDELYQRMLKGPPPEP--AASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASF 1487
Query: 1001 LADSPR-APLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASA 1059
+DSP+ L +S + Q P R P Y + +GT S P H A
Sbjct: 1488 SSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP----LHRPEA 1543
Query: 1060 SPLASQS 1066
P +S +
Sbjct: 1544 YPPSSHN 1550
Score = 32.3 bits (72), Expect = 3.6
Identities = 35/116 (30%), Positives = 41/116 (35%), Gaps = 32/116 (27%)
Query: 766 IIQN----PPPLS-----LPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQL--AAE 814
+IQN PPP S P PPQ P++ + Q L P P L ++
Sbjct: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQS-----------QPPEGPLPPAPHLPPSST 884
Query: 815 GDAVVFS--------APQEVQVTKINPPPPYPGTIPAAPTTA--APPPPLPPPQPP 860
AV S AP PP P P P T P P PPP PP
Sbjct: 885 SSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPP 940
Score = 32.0 bits (71), Expect = 4.8
Identities = 40/152 (26%), Positives = 56/152 (36%), Gaps = 28/152 (18%)
Query: 990 NNREATLKMAQLADSPRAPLQ-PLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQ 1048
++R L +A ++ R P PL+ S G +PPP L T G
Sbjct: 1204 SSRSLGLPIAASSEGHRLPGHGPLSSSAPGAS-------TQPPPHLPTKLVIRHGGAGGS 1256
Query: 1049 PGASLAHTASASPLASQSSYSLLSPPDSARD-----------RTDYVNSAFTEDEALSQH 1097
P + A AS+S +S SS S S D+ D +T S + Q
Sbjct: 1257 PSVTWAR-ASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQE 1315
Query: 1098 CQLEK--------PLRHPPLPEAAVTLKRPPP 1121
L K P+ PP P A + + PPP
Sbjct: 1316 AGLSKVVHNTALDPVHQPPPPPATLKVAEPPP 1347
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 54.7 bits (130), Expect = 7e-07
Identities = 118/520 (22%), Positives = 171/520 (32%), Gaps = 87/520 (16%)
Query: 822 APQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQT 881
+PQ VT P P P P PPPP PPP PP+ S P V Y T
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669
Query: 882 PLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTL---------PGPGSSATLRLTATEK 932
+ + SG + + P S L P P +A +
Sbjct: 670 ITRLQNAS--QHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ 727
Query: 933 KVPQPCSSATLNRLTVPRYSIP----------------TGDPPPYPEIASQLAQGRGAAQ 976
P PC+ ++P++S P PPP P I + L Q
Sbjct: 728 LKPAPCAP------SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL-----PPQ 776
Query: 977 RSDNSLIHATLRRNNREATLKMAQLA-DSPRAPLQPLAKSKGGPGGVVTQLPAR-----P 1030
L+ + + + Q A +P P+ P K P + P P
Sbjct: 777 APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836
Query: 1031 PPAL-YTCSQCSGTGPS-------------SQ-PGASLAHTASASPLASQSSYSLLSPPD 1075
PP L S C+ PS SQ P + PL + P
Sbjct: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPP 896
Query: 1076 SARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVP 1135
+ + + + S+ E L PP P + V PPP + P
Sbjct: 897 AVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956
Query: 1136 QERTAQTSG-------PNPLKLSSLMLSQG-QHLDVSRLPFISPKSPASPTATFQTGYGM 1187
++T++TS P P + SS+ S G +H + R S S +P A +
Sbjct: 957 GKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKE 1016
Query: 1188 GVPYPGSYNNP--------PLPGV-QAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYC 1238
+P P + P LPGV Q C A +P + + +VV P P +
Sbjct: 1017 TLPPPAAPPKPGKLNLSGVNLPGVLQQGC--VSAKAPVLSGRGKDSVVEFPSPPSDSDFP 1074
Query: 1239 TLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQ--NPQ 1276
PP + L LPP+ + S + P + NPQ
Sbjct: 1075 PPPPE-------TELPLPPIEIPAVFSGNTSPKVAVVNPQ 1107
Score = 46.6 bits (109), Expect = 2e-04
Identities = 93/404 (23%), Positives = 130/404 (32%), Gaps = 98/404 (24%)
Query: 954 PTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLA 1013
P PPP P + SQ A G+A + + ++T+ R + A+ L P P+
Sbjct: 639 PPPPPPPPPPLPSQSAPSAGSA--APMFVKYSTITRL-QNASQHSGALFKPPTPPVMQSQ 695
Query: 1014 KSKGG----PGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYS 1069
K P GVV P PPP PG+++A A S +S
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPT--------------PGSAMAQLKPAPCAPSLPQFS 741
Query: 1070 LLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLG 1129
PP QH P PP P L PP P+
Sbjct: 742 APPPPLKIHQ---------------VQHITQVAPPTPPPPPPIPAPL--PPQAPPKPL-- 782
Query: 1130 EDVWVPQERTAQTSGPNPLKLS----SLMLSQGQHLDVSRLPFISPKSPASPTATFQTGY 1185
V +P + +T P + + + + + +I P P P
Sbjct: 783 --VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPP-------- 832
Query: 1186 GMGVPYPGSYNNPPLPGVQAPCS--PKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPM 1243
VP P P LP Q+ C+ P LSP ++ A P PP+ P+
Sbjct: 833 ---VPVPP----PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP--PPTPPAMESQPL 883
Query: 1244 YPGSSTCSSLQLPPVALHPWSSYSACP------PMQNPQGTL--PPKPHLVVEKPLVSPP 1295
P + + P V P S+ P P P+ +L PP P V P PP
Sbjct: 884 KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943
Query: 1296 PADLQSHLGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRK 1339
P T SP P ++ GKK K
Sbjct: 944 P-------------------------TASPTPDKSGSPGKKTSK 962
Score = 45.1 bits (105), Expect = 5e-04
Identities = 73/296 (24%), Positives = 97/296 (32%), Gaps = 45/296 (15%)
Query: 1002 ADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASP 1061
A P PL P P P PPP SQ + + S+ P T +
Sbjct: 621 ASQPSPPLPPPPPPPPPPP------PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQ 674
Query: 1062 LASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPP 1121
ASQ S +L PP ++ V + P PP P +A+ +P P
Sbjct: 675 NASQHSGALFKPPTPPVMQSQSVKPQILVPP--NGVVPPPPPPPPPPTPGSAMAQLKPAP 732
Query: 1122 YQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATF 1181
P L Q S P P L + Q QH+ ++P +P P
Sbjct: 733 CA--PSL-----------PQFSAPPP----PLKIHQVQHITQ-----VAPPTPPPPPP-- 768
Query: 1182 QTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLP 1241
+P P PP P V P Q P P+ PP+ P
Sbjct: 769 -------IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV-PPAKKQPAFP 820
Query: 1242 PMY-PGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPP 1296
Y P S + +PP L S+ A P P L P P +V + PPP
Sbjct: 821 ASYIPPSPPTPPVPVPPPTLPKQQSFCAKP----PPSPLSPVPSVVKQIASQFPPP 872
Score = 44.7 bits (104), Expect = 7e-04
Identities = 96/449 (21%), Positives = 142/449 (31%), Gaps = 82/449 (18%)
Query: 770 PPPLSLPPPPQGPMQ-LSTVGH--GDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEV 826
PPP+ P PPQ P + L T+ + + A PTP + F A
Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825
Query: 827 QVTKINPPPPYPGTIPAAPTTAAPPPPLPP--------------PQPPVDVCLKKGDFSL 872
P P P T+P + A PPP P P PP ++
Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885
Query: 873 YPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEK 932
P +V Q+P + + S V P +++ P P S
Sbjct: 886 VPANVAPQSPPAVKAKPKWQPSS--IPVPSPDFPPPPPESSLVFPPPPPSP----VPAPP 939
Query: 933 KVPQPCSSATLNRLTVP-----RYSIPTG-DPPPYPEIASQLAQGRGAAQRSDNSLIHAT 986
P P +S T ++ P + S P G PPP P+ S + GA H
Sbjct: 940 PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAE--------HPE 991
Query: 987 LRRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPS 1046
+R + DS + P A+S G P PA PP
Sbjct: 992 PKRPS----------VDSLVSKFTPPAES-GSPSKETLPPPAAPP--------------- 1025
Query: 1047 SQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRH 1106
+PG + + Q S +P S R + V ++ E L
Sbjct: 1026 -KPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL 1084
Query: 1107 PPLPEAA---------VTLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQ 1157
PP+ A V + P P QW M + P P + S L+Q
Sbjct: 1085 PPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPP---------TRPKRNDSTRLTQ 1135
Query: 1158 GQHLDVSRLPFISPKSPASPTATFQTGYG 1186
+ + + + P+ P SP ++ G
Sbjct: 1136 AEISEQPTMATVVPQVPTSPKSSLSVQPG 1164
Score = 43.1 bits (100), Expect = 0.002
Identities = 143/654 (21%), Positives = 202/654 (30%), Gaps = 102/654 (15%)
Query: 642 LPEVRKISMDYINLPVFN--PNVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQ 699
L E K M+ +N P + P + + + P T + P PP P P
Sbjct: 587 LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPP 646
Query: 700 AMSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGTAEHAGD--SATQYPVSNRYSNPGQVI 757
P+QS S A V+ +T A ++H+G PV S Q++
Sbjct: 647 PPLPSQSAPSAGSA-APMFVKYSTITRLQNA---SQHSGALFKPPTPPVMQSQSVKPQIL 702
Query: 758 FGSVEMGRIIQNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDA 817
V ++ PPP PPPP P K A PQ +A
Sbjct: 703 ---VPPNGVVPPPPP---PPPPPTPGSAMAQ----------LKPAPCAPSLPQFSAPPPP 746
Query: 818 VVFSAPQEV-QVTKINPPPPYPGTIPAAPTTAAPPPPL-PPPQPPVDVCLKKGDFSLYPT 875
+ Q + QV PPPP P IPA APP PL P PT
Sbjct: 747 LKIHQVQHITQVAPPTPPPPPP--IPAPLPPQAPPKPLVTIPA---------------PT 789
Query: 876 SVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVP 935
S P + T + P + +Y P P + VP
Sbjct: 790 STKTVAP-----VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV--------PVP 836
Query: 936 QPCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREAT 995
P T+P+ PPP P L+ ++ +
Sbjct: 837 PP---------TLPKQQSFCAKPPPSP-----LSPVPSVVKQIASQFPPPPTPPAMESQP 882
Query: 996 LKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAH 1055
LK +P++P AK K P + P PPP + PS P
Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942
Query: 1056 TASASPLASQS------SYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPL 1109
+ASP +S + SP T NS+ E P P
Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG------AEHPEPKRPS 996
Query: 1110 PEAAVTLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSL----MLSQGQHLDVSR 1165
++ V+ PP P ++ P A P L LS + +L QG ++
Sbjct: 997 VDSLVSKFTPPAESGSP--SKETLPP---PAAPPKPGKLNLSGVNLPGVLQQG--CVSAK 1049
Query: 1166 LPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPC------SPKDAL---SPT 1216
P +S + S P P PLP ++ P SPK A+ P
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQ 1109
Query: 1217 QFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACP 1270
Q+++ P P L + +P V P SS S P
Sbjct: 1110 QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163
Score = 32.7 bits (73), Expect = 2.8
Identities = 40/173 (23%), Positives = 57/173 (32%), Gaps = 36/173 (20%)
Query: 1167 PFISPKSPASPTATFQTGYGMGVPY---------------PGSYNNPPLPGVQAPCSPKD 1211
P+ S P SP T Y P P PPLP AP +
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 1212 A--------LSPTQFAQQEPAVVLQPLYPPSLSYCTLPP--MYPGSSTCSSLQLPPVALH 1261
A ++ Q A Q + +P PP + ++ P + P + PP
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 1262 PWSSYSACPPM----QNPQGTLPPKP-------HLVVEKPLVSPPPADLQSHL 1303
P S+ + P PQ + PP P H+ P PPP + + L
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL 773
Score = 32.3 bits (72), Expect = 3.6
Identities = 58/271 (21%), Positives = 80/271 (29%), Gaps = 30/271 (11%)
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPP------------------PLPPPQPPVDVC 864
P+ V PP P P P P TA+P P PPP P +
Sbjct: 921 PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980
Query: 865 LKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSAT 924
+K + +P + T SG+ + P L G
Sbjct: 981 IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGV 1040
Query: 925 LRLTATEKKVPQPCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIH 984
L+ K P + + P + PPP PE L A S N+
Sbjct: 1041 LQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPK 1100
Query: 985 ATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTG 1044
+ + KM+ +AP P + K +TQ P + T T
Sbjct: 1101 VAVVNPQPQQWSKMS----VKKAP--PPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154
Query: 1045 PSS----QPG--ASLAHTASASPLASQSSYS 1069
P S QPG A L T + S S
Sbjct: 1155 PKSSLSVQPGFLADLNRTLQRKSITRHGSLS 1185
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 54.7 bits (130), Expect = 7e-07
Identities = 100/405 (24%), Positives = 132/405 (32%), Gaps = 85/405 (20%)
Query: 1004 SPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGP----SSQPGASLAHTASA 1059
SP PLQPL S G P P+ P L+ G GP S Q G L H
Sbjct: 267 SPHPPLQPLTGSAGQPSA-----PSHAQPPLH------GQGPPGPHSLQAGPLLQHPGPP 315
Query: 1060 SPL-----ASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAV 1114
P ASQ L + P +A T + A Q ++P R PLP A +
Sbjct: 316 QPFGLPPQASQGQAPLGTSPAAAYPHTSL------QLPASQSALQSQQPPREQPLPPAPL 369
Query: 1115 TLK--RPPPYQWDPMLGEDVWVPQ--ERTAQTSGPNPLKLSS----------LMLSQGQH 1160
+ +PPP P L PQ + SGP+P +++ L H
Sbjct: 370 AMPHIKPPPTTPIPQLP----APQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 425
Query: 1161 LDVSRLPFIS--------PKSPASPTATFQ-------------TGYGMGVPYPGSYNNPP 1199
+ P + P SPA P Q TG P P +P
Sbjct: 426 PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 485
Query: 1200 LPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVA 1259
+PG P +P S PA PP G S+C LP V
Sbjct: 486 VPGGPPPITPPTCPS----TSTPPAGPGTSAQPPCSGAAASGGSIAGGSSC---PLPTVQ 538
Query: 1260 LHPWSSYSACPPMQNPQGTLPPKPH-LVVEKPLVSPPPADLQSHL--GTEVMVETADNFQ 1316
+ + A P P P P VV+ P + A HL G T F
Sbjct: 539 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYF- 597
Query: 1317 EVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKE 1361
+P K KK + ++ E +A E + +KE
Sbjct: 598 ---------MPLAGSKLAKKREEAIEKAKREAEQKAREEREREKE 633
Score = 37.4 bits (85), Expect = 0.11
Identities = 78/320 (24%), Positives = 102/320 (31%), Gaps = 76/320 (23%)
Query: 770 PPPLSLPPPPQGPMQLSTVGHGDR------DHEHLQKSAKALRPT--------------- 808
P P + PPQG S + + H H+Q+ A AL P
Sbjct: 212 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ-APALHPQRPPSPHPPPHPSPHP 270
Query: 809 PQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKG 868
P G A SAP Q PP P ++ A P P PP P
Sbjct: 271 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP------------- 317
Query: 869 DFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLT 928
F L P + Q PLG + P T +L P S + L+
Sbjct: 318 -FGLPPQASQGQAPLGTSPAAAY-----------PHT---------SLQLPASQSALQSQ 356
Query: 929 ATEKKVPQPCSSATLNRLTVPRYSIPTGDPP--PYPEIASQLAQGRGAAQRSDNSLIHAT 986
++ P P + + + P PT P P P+ G + S N A
Sbjct: 357 QPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPFSMN----AN 408
Query: 987 LRRNNREATLKMAQLADSPRA---PLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGT 1043
L L P A PLQ + +S+ P PA+PP T SQ
Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS-----PAQPPG--LTQSQNLPP 461
Query: 1044 GPSSQPGASLAHTASASPLA 1063
P+S P L A P A
Sbjct: 462 PPASHPPTGLHQVAPQPPFA 481
Score = 33.9 bits (76), Expect = 1.3
Identities = 40/126 (31%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 1171 PKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPL 1230
P +P PT T VP GS QAP P+ +P + A L P
Sbjct: 202 PGTPQLPTPG-PTPSATAVPPQGSPT-----ASQAPNQPQAPTAPVPHTHIQQAPALHPQ 255
Query: 1231 YPPSLSYCTLPPMYPGSSTCSSLQ-LPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEK 1289
PPS PP +P S LQ L A P + A PP+ G PP PH +
Sbjct: 256 RPPS----PHPPPHP--SPHPPLQPLTGSAGQPSAPSHAQPPL---HGQGPPGPHSLQAG 306
Query: 1290 PLVSPP 1295
PL+ P
Sbjct: 307 PLLQHP 312
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 54.7 bits (130), Expect = 7e-07
Identities = 100/405 (24%), Positives = 132/405 (32%), Gaps = 85/405 (20%)
Query: 1004 SPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGP----SSQPGASLAHTASA 1059
SP PLQPL S G P P+ P L+ G GP S Q G L H
Sbjct: 821 SPHPPLQPLTGSAGQPSA-----PSHAQPPLH------GQGPPGPHSLQAGPLLQHPGPP 869
Query: 1060 SPL-----ASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAV 1114
P ASQ L + P +A T + A Q ++P R PLP A +
Sbjct: 870 QPFGLPPQASQGQAPLGTSPAAAYPHTSL------QLPASQSALQSQQPPREQPLPPAPL 923
Query: 1115 TLK--RPPPYQWDPMLGEDVWVPQ--ERTAQTSGPNPLKLSS----------LMLSQGQH 1160
+ +PPP P L PQ + SGP+P +++ L H
Sbjct: 924 AMPHIKPPPTTPIPQLP----APQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 979
Query: 1161 LDVSRLPFIS--------PKSPASPTATFQ-------------TGYGMGVPYPGSYNNPP 1199
+ P + P SPA P Q TG P P +P
Sbjct: 980 PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 1039
Query: 1200 LPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVA 1259
+PG P +P S PA PP G S+C LP V
Sbjct: 1040 VPGGPPPITPPTCPS----TSTPPAGPGTSAQPPCSGAAASGGSIAGGSSC---PLPTVQ 1092
Query: 1260 LHPWSSYSACPPMQNPQGTLPPKPH-LVVEKPLVSPPPADLQSHL--GTEVMVETADNFQ 1316
+ + A P P P P VV+ P + A HL G T F
Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYF- 1151
Query: 1317 EVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKE 1361
+P K KK + ++ E +A E + +KE
Sbjct: 1152 ---------MPLAGSKLAKKREEAIEKAKREAEQKAREEREREKE 1187
Score = 37.4 bits (85), Expect = 0.11
Identities = 78/320 (24%), Positives = 102/320 (31%), Gaps = 76/320 (23%)
Query: 770 PPPLSLPPPPQGPMQLSTVGHGDR------DHEHLQKSAKALRPT--------------- 808
P P + PPQG S + + H H+Q+ A AL P
Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ-APALHPQRPPSPHPPPHPSPHP 824
Query: 809 PQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKG 868
P G A SAP Q PP P ++ A P P PP P
Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP------------- 871
Query: 869 DFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLT 928
F L P + Q PLG + P T +L P S + L+
Sbjct: 872 -FGLPPQASQGQAPLGTSPAAAY-----------PHT---------SLQLPASQSALQSQ 910
Query: 929 ATEKKVPQPCSSATLNRLTVPRYSIPTGDPP--PYPEIASQLAQGRGAAQRSDNSLIHAT 986
++ P P + + + P PT P P P+ G + S N A
Sbjct: 911 QPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPFSMN----AN 962
Query: 987 LRRNNREATLKMAQLADSPRA---PLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGT 1043
L L P A PLQ + +S+ P PA+PP T SQ
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS-----PAQPPG--LTQSQNLPP 1015
Query: 1044 GPSSQPGASLAHTASASPLA 1063
P+S P L A P A
Sbjct: 1016 PPASHPPTGLHQVAPQPPFA 1035
Score = 33.9 bits (76), Expect = 1.3
Identities = 40/126 (31%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 1171 PKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPL 1230
P +P PT T VP GS QAP P+ +P + A L P
Sbjct: 756 PGTPQLPTPG-PTPSATAVPPQGSPT-----ASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809
Query: 1231 YPPSLSYCTLPPMYPGSSTCSSLQ-LPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEK 1289
PPS PP +P S LQ L A P + A PP+ G PP PH +
Sbjct: 810 RPPS----PHPPPHP--SPHPPLQPLTGSAGQPSAPSHAQPPL---HGQGPPGPHSLQAG 860
Query: 1290 PLVSPP 1295
PL+ P
Sbjct: 861 PLLQHP 866
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 54.7 bits (130), Expect = 7e-07
Identities = 100/405 (24%), Positives = 132/405 (32%), Gaps = 85/405 (20%)
Query: 1004 SPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGP----SSQPGASLAHTASA 1059
SP PLQPL S G P P+ P L+ G GP S Q G L H
Sbjct: 821 SPHPPLQPLTGSAGQPSA-----PSHAQPPLH------GQGPPGPHSLQAGPLLQHPGPP 869
Query: 1060 SPL-----ASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAV 1114
P ASQ L + P +A T + A Q ++P R PLP A +
Sbjct: 870 QPFGLPPQASQGQAPLGTSPAAAYPHTSL------QLPASQSALQSQQPPREQPLPPAPL 923
Query: 1115 TLK--RPPPYQWDPMLGEDVWVPQ--ERTAQTSGPNPLKLSS----------LMLSQGQH 1160
+ +PPP P L PQ + SGP+P +++ L H
Sbjct: 924 AMPHIKPPPTTPIPQLP----APQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH 979
Query: 1161 LDVSRLPFIS--------PKSPASPTATFQ-------------TGYGMGVPYPGSYNNPP 1199
+ P + P SPA P Q TG P P +P
Sbjct: 980 PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 1039
Query: 1200 LPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVA 1259
+PG P +P S PA PP G S+C LP V
Sbjct: 1040 VPGGPPPITPPTCPS----TSTPPAGPGTSAQPPCSGAAASGGSIAGGSSC---PLPTVQ 1092
Query: 1260 LHPWSSYSACPPMQNPQGTLPPKPH-LVVEKPLVSPPPADLQSHL--GTEVMVETADNFQ 1316
+ + A P P P P VV+ P + A HL G T F
Sbjct: 1093 IKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYF- 1151
Query: 1317 EVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKE 1361
+P K KK + ++ E +A E + +KE
Sbjct: 1152 ---------MPLAGSKLAKKREEAIEKAKREAEQKAREEREREKE 1187
Score = 37.4 bits (85), Expect = 0.11
Identities = 78/320 (24%), Positives = 102/320 (31%), Gaps = 76/320 (23%)
Query: 770 PPPLSLPPPPQGPMQLSTVGHGDR------DHEHLQKSAKALRPT--------------- 808
P P + PPQG S + + H H+Q+ A AL P
Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ-APALHPQRPPSPHPPPHPSPHP 824
Query: 809 PQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKG 868
P G A SAP Q PP P ++ A P P PP P
Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP------------- 871
Query: 869 DFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLT 928
F L P + Q PLG + P T +L P S + L+
Sbjct: 872 -FGLPPQASQGQAPLGTSPAAAY-----------PHT---------SLQLPASQSALQSQ 910
Query: 929 ATEKKVPQPCSSATLNRLTVPRYSIPTGDPP--PYPEIASQLAQGRGAAQRSDNSLIHAT 986
++ P P + + + P PT P P P+ G + S N A
Sbjct: 911 QPPREQPLPPAPLAMPHIKPP----PTTPIPQLPAPQAHKHPPHLSGPSPFSMN----AN 962
Query: 987 LRRNNREATLKMAQLADSPRA---PLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGT 1043
L L P A PLQ + +S+ P PA+PP T SQ
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS-----PAQPPG--LTQSQNLPP 1015
Query: 1044 GPSSQPGASLAHTASASPLA 1063
P+S P L A P A
Sbjct: 1016 PPASHPPTGLHQVAPQPPFA 1035
Score = 33.9 bits (76), Expect = 1.3
Identities = 40/126 (31%), Positives = 49/126 (38%), Gaps = 16/126 (12%)
Query: 1171 PKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPL 1230
P +P PT T VP GS QAP P+ +P + A L P
Sbjct: 756 PGTPQLPTPG-PTPSATAVPPQGSPT-----ASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809
Query: 1231 YPPSLSYCTLPPMYPGSSTCSSLQ-LPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEK 1289
PPS PP +P S LQ L A P + A PP+ G PP PH +
Sbjct: 810 RPPS----PHPPPHP--SPHPPLQPLTGSAGQPSAPSHAQPPL---HGQGPPGPHSLQAG 860
Query: 1290 PLVSPP 1295
PL+ P
Sbjct: 861 PLLQHP 866
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 53.9 bits (128), Expect = 1e-06
Identities = 39/139 (28%), Positives = 60/139 (43%), Gaps = 5/139 (3%)
Query: 820 FSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHY 879
F + ++ PPPP P P P PPPPLPPP P L K ++ + V
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTV-ASPVTT 2451
Query: 880 QTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCS 939
TPL ++ +TT +++ + P TR +C+ +P SS L T + P+P
Sbjct: 2452 ATPL-FDAVTTLETTAVLRSNGLPVTR-ICTTAPPPVPPKPSSIPSGLVFTHR--PEPSK 2507
Query: 940 SATLNRLTVPRYSIPTGDP 958
+ +P+ T P
Sbjct: 2508 PPIAPKPVIPQLPTTTQKP 2526
Score = 39.7 bits (91), Expect = 0.023
Identities = 71/296 (23%), Positives = 94/296 (31%), Gaps = 46/296 (15%)
Query: 1027 PARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYS--------LLSPPDSAR 1078
P++PP T G P+ QPG + A P A S + + PP
Sbjct: 301 PSKPPIQQPT----PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356
Query: 1079 DRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQER 1138
T + +Q EKP P P+A L +PP P + +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA---LAQPPGVGKTP--AQQPGPAKPP 411
Query: 1139 TAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNP 1198
T Q P PL + S + ++ P P P Q G G P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKP 469
Query: 1199 P--LPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLP 1256
P LPG P + Q+P P PP P PGS+ S Q
Sbjct: 470 PSQLPG------------PAKPPPQQPG----PAKPP--------PQQPGSAKPPSQQPG 505
Query: 1257 PVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLV-SPPPADLQSHLGTEVMVET 1311
P A P Q P T PP KP P PA + T+ + +T
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 38.1 bits (87), Expect = 0.066
Identities = 50/203 (24%), Positives = 70/203 (34%), Gaps = 30/203 (14%)
Query: 770 PPPLSLPPPPQG-----PMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQ 824
PPP LPPP P + TV L + L T L + G V
Sbjct: 2422 PPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT----- 2476
Query: 825 EVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLG 884
+ T P PP P +IP+ P P PP P V + + PT +H P G
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH-PKPTG 2535
Query: 885 YERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLN 944
++ T L + Y LP P S + + K P+ S T
Sbjct: 2536 LSLTSSM-------------TLNLVTSADYKLPSPTSPLS---PHSNKSSPRFSKSLTET 2579
Query: 945 RLTVPRYSIPTGDPPPYPEIASQ 967
+ + ++P+ P ASQ
Sbjct: 2580 YVVI---TLPSEPGTPTDSSASQ 2599
Score = 35.8 bits (81), Expect = 0.33
Identities = 85/336 (25%), Positives = 108/336 (32%), Gaps = 63/336 (18%)
Query: 1014 KSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLS- 1072
K +G P G++ + PP Q G P Q G + ++SQ + S
Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDG-------TPKSISSQQPEKIKSQ 250
Query: 1073 PPDSARD--------RTDYVNSAFTEDEALSQHCQLE-------KP-LRHPPLPEAAVTL 1116
PP + + +TD+ D + Q Q + KP L P P
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310
Query: 1117 KRPPPYQWDPMLGEDVWVPQERTAQTSG-PNPLKLSSLMLSQGQHLDVSRLPFISPKSPA 1175
PP Q P + P + AQ SG PL + + P P PA
Sbjct: 311 PGKPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
Query: 1176 SPTATFQTGY-----------------GMG---VPYPGSYNNP------PLPGVQAPC-- 1207
P A QTG G+G PG P P P Q P
Sbjct: 370 KPPAQ-QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 1208 SPKDALSPTQFAQQEPA---VVLQPLYPPSLSYC----TLPP-MYPGSSTCSSLQLPPVA 1259
SP A PT+ Q+P + Q P S T PP PG + Q P
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 1260 LHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPP 1295
P SA PP Q P T PP KP P
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
Score = 33.5 bits (75), Expect = 1.6
Identities = 30/98 (30%), Positives = 37/98 (37%), Gaps = 13/98 (13%)
Query: 772 PLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTP---------QLAAEGDAVVFSA 822
P P P + P Q LQ AKA PT ++ A+ ++
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPP 860
Q+ TK PP PG PA P P P PPPQ P
Sbjct: 461 AQQTGPTK--PPSQLPG--PAKPPPQQPGPAKPPPQQP 494
Score = 33.1 bits (74), Expect = 2.1
Identities = 30/96 (31%), Positives = 35/96 (36%), Gaps = 4/96 (4%)
Query: 767 IQNPPPLSLPPPPQGPMQLSTVGHGD-RDHEHLQKSAKALRPTPQLAAEGDAVVFSA-PQ 824
+Q P P +P GP + S G + L AK P A SA P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 825 EVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPP 860
Q PPP PG PA P+ P PP Q P
Sbjct: 501 SQQPGSTKPPPQQPG--PAKPSPQQPGSTKPPSQQP 534
Score = 32.0 bits (71), Expect = 4.8
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 23/120 (19%)
Query: 1195 YNNPPLPGVQAPCSPKDALSPTQFA------QQEPAVVLQPLYPPSLSYCTLP----PMY 1244
+++PP + P K+ LS T F Q++PA L P PS+S +LP P +
Sbjct: 2340 FDHPPSSVIALPM--KEQLSTTYFTSGETFGQEKPASQL-PSGSPSVS--SLPAKPRPFF 2394
Query: 1245 PGSSTCSSLQLPPVALHPWSSYSA--------CPPMQNPQGTLPPKPHLVVEKPLVSPPP 1296
SS S Q PP P PP +P+ T+ PK L V P+ + P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 31.6 bits (70), Expect = 6.2
Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 26/165 (15%)
Query: 1158 GQHLDVSRLPFISPKS---PASPTATFQTGYGMGV------------PYPGSYNNPPLPG 1202
GQ S+LP SP PA P F++ + + P P PP P
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSS-SLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
Query: 1203 VQAPCSPKDALSP-TQFAQQEPAVVLQPLYPPSLSYCTLPPM----YPGSSTCSSLQLPP 1257
+ P SPK + P + P PL+ + T + P + C++ PP
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-PP 2485
Query: 1258 VALHPWSSYSACPPMQNPQGTLP---PKPHLVVEKPLVSPPPADL 1299
V P S S P+ + P PKP ++ + P + P D+
Sbjct: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKP-VIPQLPTTTQKPTDI 2529
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 53.9 bits (128), Expect = 1e-06
Identities = 39/139 (28%), Positives = 60/139 (43%), Gaps = 5/139 (3%)
Query: 820 FSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHY 879
F + ++ PPPP P P P PPPPLPPP P L K ++ + V
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTV-ASPVTT 2451
Query: 880 QTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCS 939
TPL ++ +TT +++ + P TR +C+ +P SS L T + P+P
Sbjct: 2452 ATPL-FDAVTTLETTAVLRSNGLPVTR-ICTTAPPPVPPKPSSIPSGLVFTHR--PEPSK 2507
Query: 940 SATLNRLTVPRYSIPTGDP 958
+ +P+ T P
Sbjct: 2508 PPIAPKPVIPQLPTTTQKP 2526
Score = 39.7 bits (91), Expect = 0.023
Identities = 71/296 (23%), Positives = 94/296 (31%), Gaps = 46/296 (15%)
Query: 1027 PARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYS--------LLSPPDSAR 1078
P++PP T G P+ QPG + A P A S + + PP
Sbjct: 301 PSKPPIQQPT----PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356
Query: 1079 DRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQER 1138
T + +Q EKP P P+A L +PP P + +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA---LAQPPGVGKTP--AQQPGPAKPP 411
Query: 1139 TAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNP 1198
T Q P PL + S + ++ P P P Q G G P
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKP 469
Query: 1199 P--LPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLP 1256
P LPG P + Q+P P PP P PGS+ S Q
Sbjct: 470 PSQLPG------------PAKPPPQQPG----PAKPP--------PQQPGSAKPPSQQPG 505
Query: 1257 PVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLV-SPPPADLQSHLGTEVMVET 1311
P A P Q P T PP KP P PA + T+ + +T
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Score = 38.1 bits (87), Expect = 0.066
Identities = 50/203 (24%), Positives = 70/203 (34%), Gaps = 30/203 (14%)
Query: 770 PPPLSLPPPPQG-----PMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQ 824
PPP LPPP P + TV L + L T L + G V
Sbjct: 2422 PPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT----- 2476
Query: 825 EVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLG 884
+ T P PP P +IP+ P P PP P V + + PT +H P G
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH-PKPTG 2535
Query: 885 YERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLN 944
++ T L + Y LP P S + + K P+ S T
Sbjct: 2536 LSLTSSM-------------TLNLVTSADYKLPSPTSPLS---PHSNKSSPRFSKSLTET 2579
Query: 945 RLTVPRYSIPTGDPPPYPEIASQ 967
+ + ++P+ P ASQ
Sbjct: 2580 YVVI---TLPSEPGTPTDSSASQ 2599
Score = 35.8 bits (81), Expect = 0.33
Identities = 85/336 (25%), Positives = 108/336 (32%), Gaps = 63/336 (18%)
Query: 1014 KSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLS- 1072
K +G P G++ + PP Q G P Q G + ++SQ + S
Sbjct: 198 KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDG-------TPKSISSQQPEKIKSQ 250
Query: 1073 PPDSARD--------RTDYVNSAFTEDEALSQHCQLE-------KP-LRHPPLPEAAVTL 1116
PP + + +TD+ D + Q Q + KP L P P
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310
Query: 1117 KRPPPYQWDPMLGEDVWVPQERTAQTSG-PNPLKLSSLMLSQGQHLDVSRLPFISPKSPA 1175
PP Q P + P + AQ SG PL + + P P PA
Sbjct: 311 PGKPPAQ-QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
Query: 1176 SPTATFQTGY-----------------GMG---VPYPGSYNNP------PLPGVQAPC-- 1207
P A QTG G+G PG P P P Q P
Sbjct: 370 KPPAQ-QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 1208 SPKDALSPTQFAQQEPA---VVLQPLYPPSLSYC----TLPP-MYPGSSTCSSLQLPPVA 1259
SP A PT+ Q+P + Q P S T PP PG + Q P
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Query: 1260 LHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPP 1295
P SA PP Q P T PP KP P
Sbjct: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
Score = 33.5 bits (75), Expect = 1.6
Identities = 30/98 (30%), Positives = 37/98 (37%), Gaps = 13/98 (13%)
Query: 772 PLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTP---------QLAAEGDAVVFSA 822
P P P + P Q LQ AKA PT ++ A+ ++
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPP 860
Q+ TK PP PG PA P P P PPPQ P
Sbjct: 461 AQQTGPTK--PPSQLPG--PAKPPPQQPGPAKPPPQQP 494
Score = 33.1 bits (74), Expect = 2.1
Identities = 30/96 (31%), Positives = 35/96 (36%), Gaps = 4/96 (4%)
Query: 767 IQNPPPLSLPPPPQGPMQLSTVGHGD-RDHEHLQKSAKALRPTPQLAAEGDAVVFSA-PQ 824
+Q P P +P GP + S G + L AK P A SA P
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Query: 825 EVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPP 860
Q PPP PG PA P+ P PP Q P
Sbjct: 501 SQQPGSTKPPPQQPG--PAKPSPQQPGSTKPPSQQP 534
Score = 32.0 bits (71), Expect = 4.8
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 23/120 (19%)
Query: 1195 YNNPPLPGVQAPCSPKDALSPTQFA------QQEPAVVLQPLYPPSLSYCTLP----PMY 1244
+++PP + P K+ LS T F Q++PA L P PS+S +LP P +
Sbjct: 2340 FDHPPSSVIALPM--KEQLSTTYFTSGETFGQEKPASQL-PSGSPSVS--SLPAKPRPFF 2394
Query: 1245 PGSSTCSSLQLPPVALHPWSSYSA--------CPPMQNPQGTLPPKPHLVVEKPLVSPPP 1296
SS S Q PP P PP +P+ T+ PK L V P+ + P
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Score = 31.6 bits (70), Expect = 6.2
Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 26/165 (15%)
Query: 1158 GQHLDVSRLPFISPKS---PASPTATFQTGYGMGV------------PYPGSYNNPPLPG 1202
GQ S+LP SP PA P F++ + + P P PP P
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSS-SLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
Query: 1203 VQAPCSPKDALSP-TQFAQQEPAVVLQPLYPPSLSYCTLPPM----YPGSSTCSSLQLPP 1257
+ P SPK + P + P PL+ + T + P + C++ PP
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-PP 2485
Query: 1258 VALHPWSSYSACPPMQNPQGTLP---PKPHLVVEKPLVSPPPADL 1299
V P S S P+ + P PKP ++ + P + P D+
Sbjct: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKP-VIPQLPTTTQKPTDI 2529
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 53.5 bits (127), Expect = 2e-06
Identities = 131/554 (23%), Positives = 189/554 (34%), Gaps = 113/554 (20%)
Query: 797 HLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIP-----AAPTTAAPP 851
H + K TP + D VF PQ PPPP P IP + T+ PP
Sbjct: 1826 HKELFTKQPPSTPTSTSSDD--VFVKPQAP------PPPPAPSRIPIQDSLSQAQTSQPP 1877
Query: 852 PPL--------PPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRP 903
P P P+D K P P+G+ + +S+ VE C P
Sbjct: 1878 SPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP-------PVGHS-FSRRNSAAPVEN-CTP 1928
Query: 904 RTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQP----CSSATLNRLTVPRYSIPTGDPP 959
+ + S L++ T P P CSS+T N Y+ P P
Sbjct: 1929 LSSV--------------SRPLQMNETTANRPSPVRDLCSSSTTNN---DPYAKPPDTPR 1971
Query: 960 PY--------------PEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSP 1005
P P ++ Q A+G AA SD H T + + R + ++ DS
Sbjct: 1972 PVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSD----HFT-KPSPRADVFQRQRIPDSY 2026
Query: 1006 RAPLQPLAKSKGGPGGVVTQLPARPPPALY----TCSQCS---GTGPSSQPGASLAHTAS 1058
PL A GPG T P +PPP+ + SQ S P +P + +
Sbjct: 2027 ARPLLTPAPLDSGPGPFKT--PMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDN 2084
Query: 1059 ASPLASQSSYSL--LSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAV-- 1114
S S YS L+P + + + + AF++ +S+ + + P P V
Sbjct: 2085 FSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDS 2144
Query: 1115 -------TLKRPPPYQWDPMLGEDVWV-PQERTAQTSGPN-PLKLSSLMLSQGQHLDVSR 1165
PY P V P + QT P+ L ++ +H D
Sbjct: 2145 YSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSD--- 2201
Query: 1166 LPFISPKSPASPTATFQTGYGMGVPY--PGSYNNPPL-PGVQAPCSPKDALSPTQ--FAQ 1220
P+ P P G+ VPY P + P + G + L P Q F Q
Sbjct: 2202 -PYAHPPGTPRP--------GISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQ 2252
Query: 1221 ----QEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQ 1276
+ PA+ + PP T P PG S S P A P+ P Q+
Sbjct: 2253 AAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDS 2312
Query: 1277 GTLPPKPHLVVEKP 1290
H V ++P
Sbjct: 2313 FGTSQTAHDVADQP 2326
Score = 35.0 bits (79), Expect = 0.56
Identities = 65/304 (21%), Positives = 102/304 (33%), Gaps = 57/304 (18%)
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHY--Q 880
P+ V PPPPYPG I + P+ PP P K YP V
Sbjct: 2425 PENVNQAFTRPPPPYPGNIRS---------PVAPPLGPRYAVFPKDQRGPYPPDVASMGM 2475
Query: 881 TPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSS 940
P G+ F G + R L + G G S LR + +P+P ++
Sbjct: 2476 RPHGFR----FGFPGGSHGTMPSQERFLVPPQ--QIQGSGVSPQLR-RSVSVDMPRPLNN 2528
Query: 941 ATLNR-LTVPRYSIPTGDP--------PPYPEIASQLAQGRGAAQRS--DNSLIHATLRR 989
+ +N + +P++ P P Y E+ + GR S S++ A+
Sbjct: 2529 SQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEAS--- 2585
Query: 990 NNREATLKMAQLADSPRAP----LQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGP 1045
+ L+ P P P+ + P G+ QLP P P
Sbjct: 2586 ----SNLRHGNFIPRPDFPGPRHTDPMRRP---PQGLPNQLPVHP--------DLEQVPP 2630
Query: 1046 SSQPGASLAHTASA------SPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQ 1099
S Q H++S PL + S + LS + +D + + L +
Sbjct: 2631 SQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLD 2690
Query: 1100 LEKP 1103
+ P
Sbjct: 2691 SDDP 2694
>gi|31543535 R3H domain containing 1 [Homo sapiens]
Length = 1099
Score = 51.6 bits (122), Expect = 6e-06
Identities = 34/97 (35%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 767 IQNPPPLSLPPPPQGPMQ---LSTVGHGDR-DHEHLQKSAKALRPTPQLAAEGDAVVFSA 822
+ PP LP PPQ P S G + H L + A P A VV +
Sbjct: 518 VPGPPQPPLPAPPQQPAANHIFSQDNLGSQFSHMSLARQPSADGSDPHAAMFQSTVVLQS 577
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQP 859
PQ+ PPP+P P P PPPPLPP QP
Sbjct: 578 PQQSGYIMTAAPPPHP---PPPPPPPPPPPPLPPGQP 611
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 50.8 bits (120), Expect = 1e-05
Identities = 73/272 (26%), Positives = 96/272 (35%), Gaps = 54/272 (19%)
Query: 768 QNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAK-----ALRPTPQLAAEGDAVVFSA 822
+ P P PPP G + +G G L S+ L PTP A +
Sbjct: 211 RQPSPGPTPPPFPGNRG-TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD------- 262
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTP 882
K PPPP G P+ A PPPP +PPV + S P +
Sbjct: 263 -------KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Query: 883 LGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSAT 942
G + SSGN E P+ + S +T LP PG S L +E+ P P
Sbjct: 316 PGPPPLPP-SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP-PPPVRDP- 372
Query: 943 LNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLA 1002
P S P PPP G+ R+ + AT + +R
Sbjct: 373 ------PGRSGPLPPPPP--------VSRNGSTSRA----LPATPQLPSRSG-------V 407
Query: 1003 DSPRA-PLQPLAKSKGGPGGVVTQLPARPPPA 1033
DSPR+ P PL + G P PPP+
Sbjct: 408 DSPRSGPRPPLPPDRPSAGA-----PPPPPPS 434
Score = 40.0 bits (92), Expect = 0.017
Identities = 36/128 (28%), Positives = 48/128 (37%), Gaps = 21/128 (16%)
Query: 1171 PKSPASPTATFQTGYGMGVPYPGSYNN-PPLPGVQAPCSPKDALSPTQFAQQEPAVVLQP 1229
P P P + + VP P NN PP+P P + A P
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP-------------- 309
Query: 1230 LYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNP--QGTLPPKPHLVV 1287
PP S PP+ P SS + + P + S S+ PP+ +P G LPP P
Sbjct: 310 --PPPPSRPGPPPLPPSSS--GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365
Query: 1288 EKPLVSPP 1295
P+ PP
Sbjct: 366 PPPVRDPP 373
Score = 38.9 bits (89), Expect = 0.039
Identities = 61/255 (23%), Positives = 94/255 (36%), Gaps = 43/255 (16%)
Query: 834 PPPYPGT--IPAAPTTAAPPPP----LPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYER 887
PP PG +P+ + PP P +PPP+P D P S+ P
Sbjct: 143 PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRP---------DVGSKPDSIPPPVPSTPRP 193
Query: 888 ITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLT 947
I + + V P S P PG+ T + ++ P SS NR
Sbjct: 194 IQSSPHNRGSPPV--PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251
Query: 948 VP---RYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADS 1004
+P ++ PPP P + ++ + R A + +NN+ + + S
Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREA--------VPPPPPQNNKPPVPSTPRPSAS 303
Query: 1005 PRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQ-PGASLAHTASASPLA 1063
+AP P S+ GP P PP + SG + + P +L+ ++S PL
Sbjct: 304 SQAPPPPPPPSRPGP-------PPLPPSS-------SGNDETPRLPQRNLSLSSSTPPLP 349
Query: 1064 SQSSYSLLSPPDSAR 1078
S L PP S R
Sbjct: 350 SPGRSGPLPPPPSER 364
Score = 34.3 bits (77), Expect = 0.96
Identities = 72/318 (22%), Positives = 103/318 (32%), Gaps = 66/318 (20%)
Query: 771 PPLSLPP-----------PPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAV- 818
PPL LPP PP GP + G R + + P P + ++ D++
Sbjct: 126 PPL-LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184
Query: 819 --VFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTS 876
V S P+ +Q + N P +P P + P P PPP P
Sbjct: 185 PPVPSTPRPIQSSPHNRGSP---PVPGGPRQPS-PGPTPPPFPG---------------- 224
Query: 877 VHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQ 936
+ T LG G++ + P + N LP S A P
Sbjct: 225 -NRGTALG---------GGSIRQ--SPLSSSSPFSNRPPLPPTPSRAL-------DDKPP 265
Query: 937 PCSSATLNRLTVPRYSIPTGDP---------PPYPEIASQLAQGRGAAQRSDNSLIHATL 987
P NR ++ R ++P P P P +SQ R + +
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 988 RRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSS 1047
N+ L L+ S P P S G G + RPPP + SG P
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLP---SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP 382
Query: 1048 QPGASLAHTASASPLASQ 1065
P + T+ A P Q
Sbjct: 383 PPVSRNGSTSRALPATPQ 400
Score = 33.9 bits (76), Expect = 1.3
Identities = 37/142 (26%), Positives = 52/142 (36%), Gaps = 23/142 (16%)
Query: 1169 ISPKSPASPTATFQTGYGMGVP-YPGSYNNP-------PLPGVQAPCSPKDALSPTQFAQ 1220
I P P++P + + G P PG P P PG + ++ + +
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS 242
Query: 1221 QEPAVVLQPLYP-PSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPM--QNPQG 1277
P PL P PS + PP P PPV P A PP QN +
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPP----------PPVGNRPSIHREAVPPPPPQNNKP 292
Query: 1278 TLP--PKPHLVVEKPLVSPPPA 1297
+P P+P + P PPP+
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPS 314
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 50.8 bits (120), Expect = 1e-05
Identities = 73/272 (26%), Positives = 96/272 (35%), Gaps = 54/272 (19%)
Query: 768 QNPPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAK-----ALRPTPQLAAEGDAVVFSA 822
+ P P PPP G + +G G L S+ L PTP A +
Sbjct: 211 RQPSPGPTPPPFPGNRG-TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD------- 262
Query: 823 PQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTP 882
K PPPP G P+ A PPPP +PPV + S P +
Sbjct: 263 -------KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSR 315
Query: 883 LGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSAT 942
G + SSGN E P+ + S +T LP PG S L +E+ P P
Sbjct: 316 PGPPPLPP-SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP-PPPVRDP- 372
Query: 943 LNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLA 1002
P S P PPP G+ R+ + AT + +R
Sbjct: 373 ------PGRSGPLPPPPP--------VSRNGSTSRA----LPATPQLPSRSG-------V 407
Query: 1003 DSPRA-PLQPLAKSKGGPGGVVTQLPARPPPA 1033
DSPR+ P PL + G P PPP+
Sbjct: 408 DSPRSGPRPPLPPDRPSAGA-----PPPPPPS 434
Score = 40.0 bits (92), Expect = 0.017
Identities = 36/128 (28%), Positives = 48/128 (37%), Gaps = 21/128 (16%)
Query: 1171 PKSPASPTATFQTGYGMGVPYPGSYNN-PPLPGVQAPCSPKDALSPTQFAQQEPAVVLQP 1229
P P P + + VP P NN PP+P P + A P
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP-------------- 309
Query: 1230 LYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNP--QGTLPPKPHLVV 1287
PP S PP+ P SS + + P + S S+ PP+ +P G LPP P
Sbjct: 310 --PPPPSRPGPPPLPPSSS--GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365
Query: 1288 EKPLVSPP 1295
P+ PP
Sbjct: 366 PPPVRDPP 373
Score = 38.9 bits (89), Expect = 0.039
Identities = 61/255 (23%), Positives = 94/255 (36%), Gaps = 43/255 (16%)
Query: 834 PPPYPGT--IPAAPTTAAPPPP----LPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYER 887
PP PG +P+ + PP P +PPP+P D P S+ P
Sbjct: 143 PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRP---------DVGSKPDSIPPPVPSTPRP 193
Query: 888 ITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLT 947
I + + V P S P PG+ T + ++ P SS NR
Sbjct: 194 IQSSPHNRGSPPV--PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP 251
Query: 948 VP---RYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADS 1004
+P ++ PPP P + ++ + R A + +NN+ + + S
Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREA--------VPPPPPQNNKPPVPSTPRPSAS 303
Query: 1005 PRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQ-PGASLAHTASASPLA 1063
+AP P S+ GP P PP + SG + + P +L+ ++S PL
Sbjct: 304 SQAPPPPPPPSRPGP-------PPLPPSS-------SGNDETPRLPQRNLSLSSSTPPLP 349
Query: 1064 SQSSYSLLSPPDSAR 1078
S L PP S R
Sbjct: 350 SPGRSGPLPPPPSER 364
Score = 34.3 bits (77), Expect = 0.96
Identities = 72/318 (22%), Positives = 103/318 (32%), Gaps = 66/318 (20%)
Query: 771 PPLSLPP-----------PPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAV- 818
PPL LPP PP GP + G R + + P P + ++ D++
Sbjct: 126 PPL-LPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184
Query: 819 --VFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTS 876
V S P+ +Q + N P +P P + P P PPP P
Sbjct: 185 PPVPSTPRPIQSSPHNRGSP---PVPGGPRQPS-PGPTPPPFPG---------------- 224
Query: 877 VHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQ 936
+ T LG G++ + P + N LP S A P
Sbjct: 225 -NRGTALG---------GGSIRQ--SPLSSSSPFSNRPPLPPTPSRAL-------DDKPP 265
Query: 937 PCSSATLNRLTVPRYSIPTGDP---------PPYPEIASQLAQGRGAAQRSDNSLIHATL 987
P NR ++ R ++P P P P +SQ R + +
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325
Query: 988 RRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSS 1047
N+ L L+ S P P S G G + RPPP + SG P
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLP---SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP 382
Query: 1048 QPGASLAHTASASPLASQ 1065
P + T+ A P Q
Sbjct: 383 PPVSRNGSTSRALPATPQ 400
Score = 33.9 bits (76), Expect = 1.3
Identities = 37/142 (26%), Positives = 52/142 (36%), Gaps = 23/142 (16%)
Query: 1169 ISPKSPASPTATFQTGYGMGVP-YPGSYNNP-------PLPGVQAPCSPKDALSPTQFAQ 1220
I P P++P + + G P PG P P PG + ++ + +
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS 242
Query: 1221 QEPAVVLQPLYP-PSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPM--QNPQG 1277
P PL P PS + PP P PPV P A PP QN +
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPPPP----------PPVGNRPSIHREAVPPPPPQNNKP 292
Query: 1278 TLP--PKPHLVVEKPLVSPPPA 1297
+P P+P + P PPP+
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPS 314
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 5/172 (2%)
Query: 61 SSHCRRDRSTPQRIN----FNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRW 116
SS + + TP + N F L GH V V+++ + LA+ AD I +W Y+G++
Sbjct: 20 SSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKF 79
Query: 117 SVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWT 176
+ ++ +SD WS D + + D + + VS + + + + C +
Sbjct: 80 E-KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN 138
Query: 177 PDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSS 228
P ++ G+ D V + D L SD V + +N L+ SS
Sbjct: 139 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 5/172 (2%)
Query: 61 SSHCRRDRSTPQRIN----FNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRW 116
SS + + TP + N F L GH V V+++ + LA+ AD I +W Y+G++
Sbjct: 20 SSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKF 79
Query: 117 SVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWT 176
+ ++ +SD WS D + + D + + VS + + + + C +
Sbjct: 80 E-KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFN 138
Query: 177 PDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSS 228
P ++ G+ D V + D L SD V + +N L+ SS
Sbjct: 139 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 50.4 bits (119), Expect = 1e-05
Identities = 116/507 (22%), Positives = 161/507 (31%), Gaps = 113/507 (22%)
Query: 833 PPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFD 892
PPPP P PPPP PPP PP+ F L T G D
Sbjct: 247 PPPPLP----------PPPPPPPPPPPPLPGLATSPPFQL--------TKPGLWSTLHGD 288
Query: 893 SSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYS 952
+ G + P R + ++LP P P P + T +
Sbjct: 289 AWGPERKGSAPPER---QEQRHSLPHP--------------YPYPAPAYTAH--PPGHRL 329
Query: 953 IPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPL 1012
+P P P P + G A R S + RE+ ++ +++ DS +P
Sbjct: 330 VPAAPPGPGPRPPGAESHGCLPATRPPGS--------DLRESRVQRSRM-DSSVSPAATT 380
Query: 1013 AKSKGGPGGVVTQLPARPP--PALYTCSQCSGT------GPSSQPGASLAHTASASPLAS 1064
A V P+RPP P T S S + G PG A +P
Sbjct: 381 A--------CVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQ-TPALE 431
Query: 1065 QSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQW 1124
S + L P + F A + H L PP P L+ PPP W
Sbjct: 432 VSHHGRLGPSAHSS------RKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAW 485
Query: 1125 -----------DPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKS 1173
D + E+++ E + + P + V +P +
Sbjct: 486 LKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPT 545
Query: 1174 PASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDAL---------SPTQFAQQEPA 1224
P +PT + GS+++ P V P P A SP Q Q P
Sbjct: 546 PPTPTTSSSNSNS------GSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPL 599
Query: 1225 VVLQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACP-----PMQNPQGTL 1279
V L PP+ PP +T S + P + P S+ P P P
Sbjct: 600 VPLTLALPPA------PPSSCHQNTSGSFRRPE-SPRPRVSFPKTPEVGPGPPPGPLSKA 652
Query: 1280 P-PKPHLVVEKPLVSP-----PPADLQ 1300
P P P V E P P PP L+
Sbjct: 653 PQPVPPGVGELPARGPRLFDFPPTPLE 679
Score = 43.5 bits (101), Expect = 0.002
Identities = 137/615 (22%), Positives = 188/615 (30%), Gaps = 108/615 (17%)
Query: 770 PPPLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVT 829
PPPL PPPP P G L K L T A G SAP E Q
Sbjct: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTK--PGLWSTLHGDAWGPERKGSAPPERQEQ 305
Query: 830 KINPPPPYP-------------GTIPAAPTTAAPPPP-------LPPPQPPVD------V 863
+ + P PYP +PAAP P PP LP +PP V
Sbjct: 306 RHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRV 365
Query: 864 CLKKGDFSLYPTS----VHY--QTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLP 917
+ D S+ P + V Y P G TT SS + T + + +P
Sbjct: 366 QRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSS-----SSNTGLRGVEPNPGIP 420
Query: 918 GPGSSATLRLTATEKKVPQPCSSATLNRL-----TVPRYSIPTG----DPPPYPEI---- 964
G T L + P + ++ P S+P G PPP P +
Sbjct: 421 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 480
Query: 965 --ASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKG--GP- 1019
+ L A R D ++ PR PL +G GP
Sbjct: 481 PPPAWLKGPACRAAREDGEILEELFFGTE-----------GPPRPAPPPLPHREGFLGPP 529
Query: 1020 ------GGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSSYSLLSP 1073
G + P PP + S + SS P ++ P ++S L P
Sbjct: 530 ASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSF--PPPPYLARSIDPLPRP 587
Query: 1074 PDSARDRTD----YVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLG 1129
P A++ D + A S H R P P V+ + P P G
Sbjct: 588 PSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPG 647
Query: 1130 EDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTATFQTGYG--M 1187
PQ P P + L + D P + G M
Sbjct: 648 PLSKAPQ--------PVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIM 699
Query: 1188 GVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGS 1247
+ +A +P+ L +EP LQ +P + T P +
Sbjct: 700 KMLDESIRKEEEQQQHEAGVAPQPPL-------KEPFASLQSPFPTDTAPTTTAPAVAVT 752
Query: 1248 STCSSL----------QLPPVALHPWSSYSACPPMQNPQGTLPPKPH-LVVEKPLVSPPP 1296
+T ++ + PP AL P + PP PQ PP P + K L S
Sbjct: 753 TTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLE 812
Query: 1297 ADLQSHLGTEVMVET 1311
+ GT V T
Sbjct: 813 GQKYCYRGTGAAVST 827
Score = 37.0 bits (84), Expect = 0.15
Identities = 56/238 (23%), Positives = 75/238 (31%), Gaps = 43/238 (18%)
Query: 809 PQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKG 868
P +A + Q + PPP P P A P PPP PP L K
Sbjct: 747 PAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKS 806
Query: 869 DFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSAT---- 924
S+ + G TR T PGP S AT
Sbjct: 807 LASVLEGQKYCYRGTG----------------AAVSTRPGPLPTTQYSPGPPSGATALPP 850
Query: 925 LRLTATEKKVPQPCSSATLNRLT---------------VPRYSIPTGDPPPYPEIASQLA 969
+ + PQP +S++ T VP PT PPP ++ A
Sbjct: 851 TSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPP---LSLPPA 907
Query: 970 QGRGAAQRSDNSLIHATLRRNNREAT-----LKMAQLADSPRAPLQPLAKSKGGPGGV 1022
+ + + R R AT + A+ ADS L P A++K GGV
Sbjct: 908 RSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGV 965
Score = 33.1 bits (74), Expect = 2.1
Identities = 29/100 (29%), Positives = 36/100 (36%), Gaps = 24/100 (24%)
Query: 770 PPPLSL----------PPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVV 819
PPPL+ PPPP P L L+ A L A V
Sbjct: 778 PPPLAKFPPPSQPQPPPPPPPSPASL------------LKSLASVLEGQKYCYRGTGAAV 825
Query: 820 FSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQP 859
+ P + T+ +P PP T A P T+A P PQP
Sbjct: 826 STRPGPLPTTQYSPGPPSGAT--ALPPTSAAPSAQGSPQP 863
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 50.4 bits (119), Expect = 1e-05
Identities = 99/366 (27%), Positives = 136/366 (37%), Gaps = 49/366 (13%)
Query: 1004 SPRAPLQ--PLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASL--AHTASA 1059
SP +PL+ PL+ + P + P PPP S P S P L + A
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA 569
Query: 1060 SPLASQSSYSLLSPP--DSARDRTDYVNSAFT--EDEALSQHCQLEKPLRHPPLPEAAVT 1115
S L+ S +SPP +S + F E+ LS + E PL P PEA+
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE-ESPLSPP--PEAS-- 624
Query: 1116 LKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRL---PFISPK 1172
+ PP + PM P E + + P +LS L + VSRL P SP
Sbjct: 625 -RLSPPPEDSPMS-----PPPEESPMSPPPEVSRLSPLPV-------VSRLSPPPEESPL 671
Query: 1173 SP---ASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVVLQP 1229
SP SPT+ + P S +PP A P+D+L +E ++ P
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSL--MSLPLEESPLLPLP 729
Query: 1230 LYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQG------TLPPKP 1283
P P + P L P P S A P +PQ +P +P
Sbjct: 730 EEPQLCPRSEGPHLSPRP---EEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786
Query: 1284 HL--VVEKPLVSPPPADLQSHLGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRL 1341
HL E P +SP P +L HL + E L SP P+ + + L
Sbjct: 787 HLSPQAEGPHLSPQPEEL--HLSPQTEEPHLSPVPEEPCL--SPQPEESHLSPQSEEPCL 842
Query: 1342 DSRAEE 1347
R EE
Sbjct: 843 SPRPEE 848
Score = 47.0 bits (110), Expect = 1e-04
Identities = 75/284 (26%), Positives = 102/284 (35%), Gaps = 39/284 (13%)
Query: 1027 PARPPPALYTCSQCSGTGPSSQ--PGASLAHTASASPLASQSSYSLLSPPDSARDRTDYV 1084
P PPP S P+S L+ SPL+ S LSPP + +
Sbjct: 457 PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLE 516
Query: 1085 NSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTAQTSG 1144
S + E LE PL P PEA+ PP++ P+ +P + S
Sbjct: 517 ESPLSPPEESPPSPALETPLSPP--PEAS---PLSPPFEESPLSPPPEELPTSPPPEASR 571
Query: 1145 PNPLKLSSLMLSQGQHLDVSRLPFIS---PKSPASPTATFQTGYGMGVPYPGSYNNPP-- 1199
+P S M + +S P S P SP + + P S +PP
Sbjct: 572 LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE 631
Query: 1200 -----LPGVQAPCSPKDALSPTQFAQQEPAVVLQPLYPPSLSYCTLPPMYPGSSTCSSLQ 1254
P ++P SP P + ++ P V+ L PP PP P S S
Sbjct: 632 DSPMSPPPEESPMSP-----PPEVSRLSPLPVVSRLSPPPEESPLSPP--PEESPTS--- 681
Query: 1255 LPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPPAD 1298
PP P +S + PP +P T PP E SPPP D
Sbjct: 682 -PP----PEASRLSPPPEDSP--TSPPP-----EDSPASPPPED 713
Score = 40.8 bits (94), Expect = 0.010
Identities = 132/603 (21%), Positives = 193/603 (32%), Gaps = 136/603 (22%)
Query: 769 NPPPLSLP--PPPQG------PMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVF 820
+PPP P PPP+ P +L + H L P P+ +
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509
Query: 821 SAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQ 880
S ++ + ++PP P + PA T +PPP P PP ++ S P +
Sbjct: 510 SPFSPLEESPLSPPEESPPS-PALETPLSPPPEASPLSPP----FEESPLSPPPEELPTS 564
Query: 881 TPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSS 940
P R++ P P S P P +S
Sbjct: 565 PPPEASRLS---------------------------PPPEESPMSPPPEESPMSPPPEAS 597
Query: 941 ATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQ 1000
RL P P PP ++ R + D+ +
Sbjct: 598 ----RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM---------------SPP 638
Query: 1001 LADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQP--GASLAHTAS 1058
+SP +P P S+ P VV++L PPP S P+S P + L+
Sbjct: 639 PEESPMSP--PPEVSRLSPLPVVSRL--SPPPEESPLSPPPEESPTSPPPEASRLSPPPE 694
Query: 1059 ASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEAL------SQHCQLEKPLRHPPLPEA 1112
SP + S SPP D + S E+ L Q C + P PE
Sbjct: 695 DSPTSPPPEDSPASPPPE-----DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
Query: 1113 AVTLKRPPPYQWDPMLGEDVWVPQER-------------TAQTSGPN----PLKLSSLML 1155
RP P E PQ + Q GP+ P +L
Sbjct: 750 PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ 809
Query: 1156 SQGQHLD-VSRLPFISPKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALS 1214
++ HL V P +SP+ S + + S+ +P L + P SP+
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE--KPPLSPRPE-K 866
Query: 1215 PTQFAQQEPAVVLQPLYP-------------PSLSYCTLPPMYP----------GSSTCS 1251
P + Q PA PL+P P+LS PP+ P G + S
Sbjct: 867 PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLS 926
Query: 1252 SLQLPPVALHPWSS---YSACPPMQNPQGTL-------------PPKPHLVVEKPLVSPP 1295
+PP L P S +A PP +P G L P ++E P+ PP
Sbjct: 927 PQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPP 986
Query: 1296 PAD 1298
A+
Sbjct: 987 EAN 989
Score = 40.8 bits (94), Expect = 0.010
Identities = 74/314 (23%), Positives = 101/314 (32%), Gaps = 34/314 (10%)
Query: 1008 PLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTASASPLASQSS 1067
P P P G+ P P + P+ P AS+ P A Q
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPG 2224
Query: 1068 YSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLP-----EAAVTLKRPPPY 1122
+PP + R + T D L C L P P +A+ L PPP+
Sbjct: 2225 EFHTTPPGTPRHQPS------TPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPF 2278
Query: 1123 QWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLP----FISPKSP-ASP 1177
E ++ + GP L S G HL L F +P +P AS
Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNLGFVDSP-SSGTHLGGLELKTPDVFKAPLTPRASQ 2337
Query: 1178 TATFQTGYGMGVPYPGSYNNPPLPGVQ-APCSPKDALSPTQFAQQ--EPAVVLQPLYPPS 1234
G G+ P PP + +P S D P + +P + +P PP
Sbjct: 2338 VEPQSPGLGLRPQEP-----PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392
Query: 1235 LSYCTLPP---------MYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKPHL 1285
S C LPP P S S P+ P S+ + CP P+ P
Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR 2452
Query: 1286 VVEKPLVSPPPADL 1299
+P P A L
Sbjct: 2453 PPSRPQSRDPFAPL 2466
Score = 39.7 bits (91), Expect = 0.023
Identities = 106/460 (23%), Positives = 150/460 (32%), Gaps = 72/460 (15%)
Query: 772 PLSLPPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQ---LAAEGDAVVFSAPQEVQ- 827
PLS PPP + P+ A L P P+ ++ + S P EV
Sbjct: 607 PLS-PPPEESPLSPPP-------------EASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Query: 828 ------VTKINPPP------PYPGTIPAAPTTAA-------------PPPPLPPPQPPVD 862
V++++PPP P P P +P A PPP P PP +
Sbjct: 653 LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712
Query: 863 VCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEVC---RPRTRMLCSQ--NTYTLP 917
L P + P R S EE RP L Q + P
Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772
Query: 918 GPGSSATLRLTATEKKVPQ---PCSSATLNRLTV-PRYSIPTGDPPPYPEIASQLAQGRG 973
P + PQ P S L + P+ P P P S +
Sbjct: 773 QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH 832
Query: 974 AAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPA 1033
+ +S+ + ++ L+ L+ P P + + G +LP PPP
Sbjct: 833 LSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE-----EPGQCPAPEELPLFPPPG 887
Query: 1034 LYTCSQCSGTGPSSQPG----ASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFT 1089
+ S G S+PG + L SP S L PPD + +A
Sbjct: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA-A 946
Query: 1090 EDEALSQHCQLEKPL-----RHPPLPEAAVTLKRP--PPYQ---WDPMLGEDVWVPQERT 1139
ALS +LE P P P AA L+ P PP + DP + +P
Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006
Query: 1140 AQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASPTA 1179
+ +P+ + L L S +P SP S SP A
Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPA 1046
Score = 37.7 bits (86), Expect = 0.087
Identities = 88/390 (22%), Positives = 127/390 (32%), Gaps = 91/390 (23%)
Query: 819 VFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVH 878
VF AP + +++ P P G P P A P PP P + + G + T +
Sbjct: 2326 VFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI---FRPGSY----TDPY 2378
Query: 879 YQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPC 938
Q PL T E C R L S +P S + ++ P+P
Sbjct: 2379 AQPPL-----TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQS---SSQSPLTPRPL 2430
Query: 939 SS-ATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLK 997
S+ A PR+ P DP P Q R + +H R E K
Sbjct: 2431 SAEAFCPSPVTPRFQSP--DPYSRPPSRPQ--------SRDPFAPLHKPPRPQPPEVAFK 2480
Query: 998 MAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSGTGPSSQPGASLAHTA 1057
LA + G GG LPA P L+ PS QP
Sbjct: 2481 AGSLAHTSL-----------GAGGFPAALPAGPAGELH------AKVPSGQP-------- 2515
Query: 1058 SASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLK 1117
+ + S + + + P R FT +A+ + P PP+P+ +
Sbjct: 2516 -PNFVRSPGTGAFVGTPSPMR---------FTFPQAVGE------PSLKPPVPQPGL--- 2556
Query: 1118 RPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFISPKSPASP 1177
PPP+ + GP P +L Q + V+ F SP P
Sbjct: 2557 -PPPHGINSHF---------------GPGP----TLGKPQSTNYTVATGNFHPSGSPLGP 2596
Query: 1178 TA-TFQTGYGMGVPYPGSYNNPPLPGVQAP 1206
++ + YG+ P S PP P P
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLPPPAPDGSLP 2626
Score = 36.6 bits (83), Expect = 0.19
Identities = 86/371 (23%), Positives = 128/371 (34%), Gaps = 51/371 (13%)
Query: 771 PPLSLPP--PPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQV 828
PPLS P PP+ P Q + S L P L+ G+ + P+E+
Sbjct: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEEL-- 915
Query: 829 TKINPPPPYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERI 888
P P P+ PP PLPPP P+ +L P + P G +
Sbjct: 916 ------PLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP--ALSPLG-ELEYPFGAKGD 966
Query: 889 TTFDS---SGNVEEVCRPRTRMLCSQ-----NTYTLPGPGSSATLRLTATEKKVPQPCSS 940
+ +S + +E P C+ P PGS + +P C S
Sbjct: 967 SDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQC-S 1025
Query: 941 ATLNRLTVPRYSIPTG-DPPPYP-EIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKM 998
L VP+ S P+ PP P + S L+ SD + +H ++
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELH----------EMET 1075
Query: 999 AQLADSPRAPLQPLAKSK-GGPGGVVTQLPARPPPALYTCSQCSGTG-----------PS 1046
++++ L+P A S P G ++ P PAL SG G P
Sbjct: 1076 EKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPAL---DDFSGLGEDTAPLDGIDAPG 1132
Query: 1047 SQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRH 1106
SQP + AS L + S LL P + A V + C+ ++ R
Sbjct: 1133 SQPEPGQTPGSLASEL--KGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRA 1190
Query: 1107 PPLPEAAVTLK 1117
P P +K
Sbjct: 1191 PVAPTPPTLIK 1201
Score = 36.6 bits (83), Expect = 0.19
Identities = 48/216 (22%), Positives = 76/216 (35%), Gaps = 11/216 (5%)
Query: 776 PPPPQGPMQLSTVGHGDRDHEHLQKSAKALRPTPQLAAEGDAVVFSAPQEVQVTKINPPP 835
P P GP+Q G + L AL P L S+PQE + P
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPK-----RPS 4321
Query: 836 PYPGTIPAAPTTAAPPPPLPPPQPPVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSG 895
P PT A PP P P L+ + P + L + + +D
Sbjct: 4322 QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPD 4381
Query: 896 NVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATEKKVPQPCSSATLNRLTVPRYSIPT 955
N+ E +P L + + G +L+ ++ +PC+ L +V R +
Sbjct: 4382 NLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCA---LGAQSVKREA--N 4436
Query: 956 GDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNN 991
G+P P ++ L G + + L+ LR N
Sbjct: 4437 GEPIGAPGTSNHLLLA-GPRSEAGHLLLQKLLRAKN 4471
Score = 35.0 bits (79), Expect = 0.56
Identities = 37/131 (28%), Positives = 46/131 (35%), Gaps = 8/131 (6%)
Query: 1167 PFISPKSPASPTATFQTGYGMGVPYPGSYNNPPLPGVQAPCSPKDALSPTQFAQQEPAVV 1226
P I SP +P + G P GS P PG P P Q Q+P
Sbjct: 2122 PTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV--PAQVPSQDP-FG 2178
Query: 1227 LQPLYPPSLSYCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQ---NPQGTLPPKP 1283
L P YP + T PP YP + + P L S A P + P GT P+
Sbjct: 2179 LAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGT--PRH 2236
Query: 1284 HLVVEKPLVSP 1294
P + P
Sbjct: 2237 QPSTPDPFLKP 2247
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,610,766
Number of Sequences: 37866
Number of extensions: 4080798
Number of successful extensions: 32124
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 745
Number of HSP's that attempted gapping in prelim test: 19792
Number of HSP's gapped (non-prelim): 7970
length of query: 1543
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1428
effective length of database: 13,892,928
effective search space: 19839101184
effective search space used: 19839101184
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.