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Search of human proteins with 55953076
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55953076 connexin 50 [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55953076 connexin 50 [Homo sapiens] 872 0.0
gi|22779877 connexin 46 [Homo sapiens] 340 1e-93
gi|32483412 connexin 40 [Homo sapiens] 312 3e-85
gi|6631083 connexin 40 [Homo sapiens] 312 3e-85
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 285 4e-77
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 282 5e-76
gi|4504001 connexin 43 [Homo sapiens] 270 2e-72
gi|62865885 connexin 37 [Homo sapiens] 265 8e-71
gi|42558283 gap junction protein beta 2 [Homo sapiens] 239 4e-63
gi|122939172 connexin 45 [Homo sapiens] 238 6e-63
gi|69122473 connexin 45 [Homo sapiens] 238 6e-63
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 229 3e-60
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 229 3e-60
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 229 3e-60
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 229 3e-60
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 225 5e-59
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 220 2e-57
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 218 8e-57
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 218 8e-57
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 200 2e-51
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 198 7e-51
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 198 9e-51
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 194 1e-49
gi|54607056 connexin 31 [Homo sapiens] 190 2e-48
gi|13128960 connexin 31 [Homo sapiens] 190 2e-48
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 147 2e-35
gi|145699105 connexin40.1 [Homo sapiens] 146 4e-35
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 96 5e-20
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 96 5e-20
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 96 5e-20
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 872 bits (2253), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
Sbjct: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
Sbjct: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
Query: 121 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL 180
NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
Sbjct: 121 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL 180
Query: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV 240
YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
Sbjct: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV 240
Query: 241 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF 300
EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
Sbjct: 241 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF 300
Query: 301 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE 360
EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
Sbjct: 301 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE 360
Query: 361 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS 420
QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
Sbjct: 361 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS 420
Query: 421 KASSRARSDDLTV 433
KASSRARSDDLTV
Sbjct: 421 KASSRARSDDLTV 433
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 340 bits (872), Expect = 1e-93
Identities = 201/445 (45%), Positives = 245/445 (55%), Gaps = 22/445 (4%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDWSFLG +LE EHSTVIG+VWLTVLFIFRIL+LG AAE VWGDEQSDF CNTQQPG
Sbjct: 1 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
CENVCYD AFPISHIR W LQIIFVSTP+L+Y+GH +H VRMEEK+K RE EE Q
Sbjct: 61 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEE--QLKRE 118
Query: 121 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL 180
+ P + S + R+ G LLRTY+ +IIFKTLFEVGFI G YFLYGF + PL
Sbjct: 119 SPSPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPL 178
Query: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV 240
YRC RWPCPN VDCF+SRPTEKTIFI+FML+VA SL LN++E+ HLG K ++ + +
Sbjct: 179 YRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRL 238
Query: 241 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPFN 298
E P + + + + PL + V +P PA F
Sbjct: 239 GPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFK 298
Query: 299 --QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPA----EEGAEPEVGEKKEE 352
E G L G+ L + Q E + PPA + P
Sbjct: 299 LLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALKAYPAASTPAAPSPVGS 357
Query: 353 AERLTTEEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELT 409
+ E E A P +G G G EE + + + P L
Sbjct: 358 SSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PPLP 410
Query: 410 TDDARPLSRLSKASS-RARSDDLTV 433
D S+ S+ASS RAR +DL +
Sbjct: 411 LGDPGRASKASRASSGRARPEDLAI 435
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 312 bits (800), Expect = 3e-85
Identities = 188/435 (43%), Positives = 243/435 (55%), Gaps = 79/435 (18%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDWSFLGN LEEV++HSTV+G+VWLTVLFIFR+L+LGTAAE WGDEQ+DF C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
C+NVCYD+AFPISHIR WVLQIIFVSTPSL+Y+GHA+H VRM+EKRK REAE + G+
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
Query: 121 NG--GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL 178
P + S +G + L+GTLL TY+C I+ +T EVGFIVG YF+YG +
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
Query: 179 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR 238
L+ C R PCP+ V+C+VSRPTEK +FI+FML+VA++SL L++ EL HLG K IR +
Sbjct: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
Query: 239 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN 298
P + + VG+V+ S P FN
Sbjct: 241 P-------------------------------RQHMAKCQLSGPSVGIVQ-SCTPPPDFN 268
Query: 299 QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTT 358
Q + GP G + + S ++ + V E+ E+ T
Sbjct: 269 QC---LENGPGGKFFNPFSNNMAS----------------QQNTDNLVTEQVRGQEQ--T 307
Query: 359 EEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSR 418
+ + V G+K E P G + P D R R
Sbjct: 308 PGEGFIQVRYGQKPEVPNGVSPGHR---------------------LPHGYHSDKR---R 343
Query: 419 LSKASSRARSDDLTV 433
LSKASS+ARSDDL+V
Sbjct: 344 LSKASSKARSDDLSV 358
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 312 bits (800), Expect = 3e-85
Identities = 188/435 (43%), Positives = 243/435 (55%), Gaps = 79/435 (18%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDWSFLGN LEEV++HSTV+G+VWLTVLFIFR+L+LGTAAE WGDEQ+DF C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
C+NVCYD+AFPISHIR WVLQIIFVSTPSL+Y+GHA+H VRM+EKRK REAE + G+
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120
Query: 121 NG--GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL 178
P + S +G + L+GTLL TY+C I+ +T EVGFIVG YF+YG +
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT 180
Query: 179 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR 238
L+ C R PCP+ V+C+VSRPTEK +FI+FML+VA++SL L++ EL HLG K IR +
Sbjct: 181 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK 240
Query: 239 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN 298
P + + VG+V+ S P FN
Sbjct: 241 P-------------------------------RQHMAKCQLSGPSVGIVQ-SCTPPPDFN 268
Query: 299 QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTT 358
Q + GP G + + S ++ + V E+ E+ T
Sbjct: 269 QC---LENGPGGKFFNPFSNNMAS----------------QQNTDNLVTEQVRGQEQ--T 307
Query: 359 EEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSR 418
+ + V G+K E P G + P D R R
Sbjct: 308 PGEGFIQVRYGQKPEVPNGVSPGHR---------------------LPHGYHSDKR---R 343
Query: 419 LSKASSRARSDDLTV 433
LSKASS+ARSDDL+V
Sbjct: 344 LSKASSKARSDDLSV 358
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 285 bits (730), Expect = 4e-77
Identities = 135/245 (55%), Positives = 180/245 (73%), Gaps = 12/245 (4%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDW+ LG ILEEV+ HST++G++WLT+LFIFR+L+L AAE VW DEQS F CNT+QPG
Sbjct: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
C N+CYD+AFPIS IR WVLQIIFVS+PSL+Y+GHA++ +R EK + R+ L Q
Sbjct: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQM-- 118
Query: 121 NGGPD---------QGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYF 171
PD +++ K K L+G LLRTY+ HI+ +++ EVGF++G Y
Sbjct: 119 -ENPDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYI 177
Query: 172 LYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKG 231
LYGF++ PLY+C++ PCPN VDCFVSRPTEKTIF+LFM S+A++SL LN++E+ HLG++
Sbjct: 178 LYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRK 237
Query: 232 IRSAL 236
I L
Sbjct: 238 IMRTL 242
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 282 bits (721), Expect = 5e-76
Identities = 132/242 (54%), Positives = 181/242 (74%), Gaps = 6/242 (2%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDW+ LG+ LEEV+ HST+IG++WLT+LFIFR+L+LG AAE VW DEQS F+CNT+QPG
Sbjct: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELG---QQ 117
C NVCYD+AFPIS IR WVLQ+IFVS+PSL+Y+GHA++ +R+ E+ + R +L ++
Sbjct: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
Query: 118 AGTNGGPDQGSVKKSSGSKGTKKFR---LEGTLLRTYICHIIFKTLFEVGFIVGHYFLYG 174
D+ +++ +K L GTLL TY+ HI +++ EVGF++G Y LYG
Sbjct: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180
Query: 175 FRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRS 234
F + PL++C PCPN++DCFVSRPTEKTIF+LFM S+A++SLFLN++E+ HLG K I+
Sbjct: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240
Query: 235 AL 236
L
Sbjct: 241 GL 242
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 270 bits (689), Expect = 2e-72
Identities = 133/241 (55%), Positives = 176/241 (73%), Gaps = 4/241 (1%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDWS LG +L++V +ST G+VWL+VLFIFRIL+LGTA E WGDEQS F CNTQQPG
Sbjct: 1 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE-ELGQQAG 119
CENVCYD++FPISH+R WVLQIIFVS P+L+Y+ H + +R EEK +E E ++ Q G
Sbjct: 61 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG 120
Query: 120 TNGGP--DQGSVKK-SSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFR 176
N Q +KK G + K ++ G LLRTYI I+FK++FEV F++ +++YGF
Sbjct: 121 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS 180
Query: 177 ILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL 236
+ +Y C R PCP+ VDCF+SRPTEKTIFI+FML V+ VSL LN++EL ++ KG++ +
Sbjct: 181 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRV 240
Query: 237 K 237
K
Sbjct: 241 K 241
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 265 bits (676), Expect = 8e-71
Identities = 127/233 (54%), Positives = 165/233 (70%), Gaps = 8/233 (3%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MGDW FL +L++V EHSTV+G++WLTVLFIFRILILG A E VWGDEQSDF CNT QPG
Sbjct: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAE------EL 114
C NVCYD+AFPISHIR WVLQ +FVSTP+L+Y+GH ++ R EE+ + +E E +
Sbjct: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120
Query: 115 GQQAGTNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYG 174
Q ++ K S G + R+ G L+ TY+ ++ K++ E GF+ G + LYG
Sbjct: 121 PQVERALAAVERQMAKISVAEDG--RLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYG 178
Query: 175 FRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227
+ + P++ C R PCP +VDCFVSRPTEKTIFI+FML V +SL LN++EL HL
Sbjct: 179 WTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHL 231
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 239 bits (610), Expect = 4e-63
Identities = 125/239 (52%), Positives = 160/239 (66%), Gaps = 15/239 (6%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
DW L IL VN+HST IG++WLTVLFIFRI+IL AA+ VWGDEQ+DFVCNT QPGC+
Sbjct: 2 DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCK 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYD FPISHIRLW LQ+IFVSTP+L+ H V Y R E+KRK + E +
Sbjct: 62 NVCYDHYFPISHIRLWALQLIFVSTPALLVAMH-VAYRRHEKKRKFIKGEIKSE------ 114
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPLY 181
D +K T+K R+EG+L TY I F+ +FE F+ Y +Y GF + L
Sbjct: 115 FKDIEEIK-------TQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLV 167
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV 240
+C+ WPCPN VDCFVSRPTEKT+F +FM++V+ + + LNV EL +L ++ K+PV
Sbjct: 168 KCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV 226
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 238 bits (608), Expect = 6e-63
Identities = 118/273 (43%), Positives = 167/273 (61%), Gaps = 36/273 (13%)
Query: 4 WSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCEN 63
WSFL +LEE++ HST +G++WLTVL +FRI++ E ++ DEQS FVCNT+QPGCEN
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV--------------------RME 103
VCYD P+SH+R WV QII V+TPS+MY+G+A+H + R +
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 104 EKRKSREAEELGQQ----------AGTNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYIC 153
+ R E EE ++ +Q K G ++ R +G L++ Y+
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHD--GRRRIREDG-LMKIYVL 179
Query: 154 HIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVA 213
++ +T+FEVGF++G YFLYGF++ P Y CSR PCP+ +DCF+SRPTEKTIF+L M V
Sbjct: 180 QLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239
Query: 214 SVSLFLNVMELGHLGLKGIRSAL---KRPVEQP 243
+ L LN+ E+ HLG IR +L +R +E P
Sbjct: 240 GLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDP 272
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 238 bits (608), Expect = 6e-63
Identities = 118/273 (43%), Positives = 167/273 (61%), Gaps = 36/273 (13%)
Query: 4 WSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCEN 63
WSFL +LEE++ HST +G++WLTVL +FRI++ E ++ DEQS FVCNT+QPGCEN
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 VCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV--------------------RME 103
VCYD P+SH+R WV QII V+TPS+MY+G+A+H + R +
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 104 EKRKSREAEELGQQ----------AGTNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYIC 153
+ R E EE ++ +Q K G ++ R +G L++ Y+
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHD--GRRRIREDG-LMKIYVL 179
Query: 154 HIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVA 213
++ +T+FEVGF++G YFLYGF++ P Y CSR PCP+ +DCF+SRPTEKTIF+L M V
Sbjct: 180 QLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239
Query: 214 SVSLFLNVMELGHLGLKGIRSAL---KRPVEQP 243
+ L LN+ E+ HLG IR +L +R +E P
Sbjct: 240 GLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDP 272
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 229 bits (585), Expect = 3e-60
Identities = 117/229 (51%), Positives = 152/229 (66%), Gaps = 15/229 (6%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
DW L + VN+HST IG+VW+TV+FIFR++IL AA+ VWGDEQ DFVCNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYD FP+SHIRLW LQ+IFVSTP+L+ H +Y R E RK R E+ N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEK------RND 114
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPLY 181
D +KK +K R+EG+L TY I F+ +FE F+ YFLY G+ + +
Sbjct: 115 FKDIEDIKK-------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVL 167
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLK 230
+C PCPN+VDCF+SRPTEKT+F +FM+S + + + LNV EL +L LK
Sbjct: 168 KCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLK 216
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 229 bits (585), Expect = 3e-60
Identities = 117/229 (51%), Positives = 152/229 (66%), Gaps = 15/229 (6%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
DW L + VN+HST IG+VW+TV+FIFR++IL AA+ VWGDEQ DFVCNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYD FP+SHIRLW LQ+IFVSTP+L+ H +Y R E RK R E+ N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEK------RND 114
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPLY 181
D +KK +K R+EG+L TY I F+ +FE F+ YFLY G+ + +
Sbjct: 115 FKDIEDIKK-------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVL 167
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLK 230
+C PCPN+VDCF+SRPTEKT+F +FM+S + + + LNV EL +L LK
Sbjct: 168 KCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLK 216
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 229 bits (585), Expect = 3e-60
Identities = 117/229 (51%), Positives = 152/229 (66%), Gaps = 15/229 (6%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
DW L + VN+HST IG+VW+TV+FIFR++IL AA+ VWGDEQ DFVCNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYD FP+SHIRLW LQ+IFVSTP+L+ H +Y R E RK R E+ N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEK------RND 114
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPLY 181
D +KK +K R+EG+L TY I F+ +FE F+ YFLY G+ + +
Sbjct: 115 FKDIEDIKK-------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVL 167
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLK 230
+C PCPN+VDCF+SRPTEKT+F +FM+S + + + LNV EL +L LK
Sbjct: 168 KCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLK 216
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 229 bits (585), Expect = 3e-60
Identities = 117/229 (51%), Positives = 152/229 (66%), Gaps = 15/229 (6%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
DW L + VN+HST IG+VW+TV+FIFR++IL AA+ VWGDEQ DFVCNT QPGC+
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYD FP+SHIRLW LQ+IFVSTP+L+ H +Y R E RK R E+ N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEK------RND 114
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPLY 181
D +KK +K R+EG+L TY I F+ +FE F+ YFLY G+ + +
Sbjct: 115 FKDIEDIKK-------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVL 167
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLK 230
+C PCPN+VDCF+SRPTEKT+F +FM+S + + + LNV EL +L LK
Sbjct: 168 KCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLK 216
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 225 bits (574), Expect = 5e-59
Identities = 115/295 (38%), Positives = 167/295 (56%), Gaps = 62/295 (21%)
Query: 4 WSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCEN 63
WSFL +LEE++ HST +G+VWLTVL +FRI++ E ++ DEQ+ F CNT+QPGC+N
Sbjct: 6 WSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDN 65
Query: 64 VCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV----------------------- 100
VCYD P+SH+R WV QI+ +STPS+MY+G+AVH +
Sbjct: 66 VCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPR 125
Query: 101 --------------------------RMEEKRKSREAEELGQQAGTNGGPDQ-----GSV 129
EE+ ++ AE G++A G + G+
Sbjct: 126 AHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTKAVGAD 185
Query: 130 KKSSGS-------KGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYR 182
K++G+ G ++ + EG L+R Y+ ++ + FEV F+VG Y LYGF + P +
Sbjct: 186 GKAAGTPGPTGQHDGRRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFP 244
Query: 183 CSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALK 237
CSR PCP+VVDCFVSRPTEKT+F+L M V+ + L LN+ E+ HLGL + A++
Sbjct: 245 CSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVR 299
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 220 bits (560), Expect = 2e-57
Identities = 123/314 (39%), Positives = 176/314 (56%), Gaps = 50/314 (15%)
Query: 1 MGDWSFLGNILEE-VNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQP 59
MG+W+ L +LE V +HST+IGR+ LTV+ IFRILI+ E V+ DEQ+ FVCNT QP
Sbjct: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
Query: 60 GCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHY-VRMEEKRKSR--------E 110
GC CYD AFPISHIR WV QII V TPSL ++ ++VH + E+R S
Sbjct: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDP 120
Query: 111 AEELGQQAGTNGGPDQGSVKK----------------SSGSKGTK--------------- 139
E +G GT GG G ++ + SK T+
Sbjct: 121 PESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPSG 180
Query: 140 -------KFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVV 192
K R + + R YI ++F+ E+GF+VG YFLYGF + LY C+R+PC V
Sbjct: 181 LRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEV 240
Query: 193 DCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALK--RPVEQPLGEIPEK 250
+C+VSRPTEKT+F++FM +V+ + + LN+ EL HLG + I+ A++ + + + EI K
Sbjct: 241 ECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNK 300
Query: 251 SLHSIAVSSIQKAK 264
L ++V + + +
Sbjct: 301 DLPRVSVPNFGRTQ 314
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 218 bits (555), Expect = 8e-57
Identities = 111/243 (45%), Positives = 152/243 (62%), Gaps = 18/243 (7%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
+W+ L +L VN HST IGRVWL+V+FIFRI++L AAE VWGDE+S F+CNT QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
+VCYD+ FPISH+RLW LQ+I VSTP+L+ H H +E+K E +G
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEG---------HG 112
Query: 123 GP-DQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPL 180
P VK+ K + GTL TY+ ++F+ LFE F+ Y LY G+ ++ L
Sbjct: 113 DPLHLEEVKR-------HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRL 165
Query: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV 240
+C +PCPN VDCFVSRPTEKT+F +FML+ + + + LNV E+ +L ++ +R
Sbjct: 166 VKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRS 225
Query: 241 EQP 243
P
Sbjct: 226 NPP 228
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 218 bits (555), Expect = 8e-57
Identities = 111/243 (45%), Positives = 152/243 (62%), Gaps = 18/243 (7%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
+W+ L +L VN HST IGRVWL+V+FIFRI++L AAE VWGDE+S F+CNT QPGC
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
+VCYD+ FPISH+RLW LQ+I VSTP+L+ H H +E+K E +G
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEG---------HG 112
Query: 123 GP-DQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPL 180
P VK+ K + GTL TY+ ++F+ LFE F+ Y LY G+ ++ L
Sbjct: 113 DPLHLEEVKR-------HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRL 165
Query: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV 240
+C +PCPN VDCFVSRPTEKT+F +FML+ + + + LNV E+ +L ++ +R
Sbjct: 166 VKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRS 225
Query: 241 EQP 243
P
Sbjct: 226 NPP 228
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 200 bits (509), Expect = 2e-51
Identities = 106/242 (43%), Positives = 151/242 (62%), Gaps = 28/242 (11%)
Query: 4 WSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCEN 63
W FL ++L VN++ST G +WL V+F+FR+L+ AAE VW DEQ +F CN++QPGC+N
Sbjct: 3 WMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKN 62
Query: 64 VCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNGG 123
VC+D+ FPIS +RLW LQ+I VSTPSL+ V H ++ E R+ R ++L GT
Sbjct: 63 VCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYH----EGREKRHRKKLYVSPGT--- 115
Query: 124 PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPLYR 182
++G L Y+ +I KT FE+GF+V Y LY GF + L +
Sbjct: 116 -------------------MDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIK 156
Query: 183 CSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLK-GIRSALKRPVE 241
C PCPN VDCF+S+PTEKTIFILF++ + + + LN +EL L LK I+ L++ ++
Sbjct: 157 CDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLKCFIKCCLQKYLK 216
Query: 242 QP 243
+P
Sbjct: 217 KP 218
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 198 bits (504), Expect = 7e-51
Identities = 101/235 (42%), Positives = 146/235 (62%), Gaps = 20/235 (8%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
+WS +L VN++ST GR+WL+++FIFR+L+ AE VW D+ DF CNT+QPGC
Sbjct: 2 NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVC+DE FP+SH+RLW LQ+I V+ PSL+ V H V Y ++EKR REA
Sbjct: 62 NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMH-VAYREVQEKR-HREAH---------- 109
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFI-VGHYFLYGFRILPLY 181
G + G + + G K G L TY+C ++FK ++ F+ V H F + + P+
Sbjct: 110 GENSGRLYLNPGKK-------RGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVV 162
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL 236
+C PCPN+VDCF+S+P+EK IF LFM++ A++ + LN++EL +L K L
Sbjct: 163 KCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECL 217
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 198 bits (503), Expect = 9e-51
Identities = 98/231 (42%), Positives = 141/231 (61%), Gaps = 15/231 (6%)
Query: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
MG+W+FLG++L+ V S ++GR+WL V+ IFRIL+L T V+ DEQ +FVCNT QPG
Sbjct: 1 MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
Query: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
C CYD AFP+SH R W+ I+ +S P +++V +++H R +EA G +A
Sbjct: 61 CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMH-------RAGKEAG--GAEAAA 111
Query: 121 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL 180
P + + + ++ R R Y+ + + L E+ F+ G LYGFR+ P
Sbjct: 112 QCAPGLPEAQCAPCALRARRAR------RCYLLSVALRLLAELTFLGGQALLYGFRVAPH 165
Query: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKG 231
+ C+ PCP+ VDCFVSRPTEKT+F+LF +V +S L+V ELGHL KG
Sbjct: 166 FACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKG 216
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 194 bits (494), Expect = 1e-49
Identities = 100/226 (44%), Positives = 141/226 (62%), Gaps = 20/226 (8%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
+W+FL +L VN++STV+ R+WL+V+FIFR+L+ AAE VW DEQ DFVCNT+QPGC
Sbjct: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYDE FP+SH+RLW LQ+I V+ PSL+ V H + R E +RK
Sbjct: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAY--REERERKHH----------LKH 109
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP-LY 181
GP+ S+ + K G L TY+ +IFK + GF+ + LY +P +
Sbjct: 110 GPNAPSLYDNLSKK-------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVV 162
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227
CS PCP+ VDC++SRPTEK +F FM++ A++ + LN+ E+ +L
Sbjct: 163 ACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYL 208
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 190 bits (482), Expect = 2e-48
Identities = 100/227 (44%), Positives = 141/227 (62%), Gaps = 21/227 (9%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
DW L +L VN++ST GR+WL+V+F+FR+L+ AAE VWGDEQ DF CNT+QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYD FPIS+IRLW LQ+IFV+ PSL+ + H V E+R+ R ++ G Q
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILH----VAYREERERRHRQKHGDQC---- 113
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFI-VGHYFLYGFRILPLY 181
+ ++G K G L TY+ +IFK + E F+ + H +GF + L
Sbjct: 114 ----AKLYDNAGKK-------HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLV 162
Query: 182 RCSR-WPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227
+C+ PCPN+VDC+++RPTEK IF FM+ ++V + L + EL +L
Sbjct: 163 QCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 190 bits (482), Expect = 2e-48
Identities = 100/227 (44%), Positives = 141/227 (62%), Gaps = 21/227 (9%)
Query: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
DW L +L VN++ST GR+WL+V+F+FR+L+ AAE VWGDEQ DF CNT+QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
NVCYD FPIS+IRLW LQ+IFV+ PSL+ + H V E+R+ R ++ G Q
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILH----VAYREERERRHRQKHGDQC---- 113
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFI-VGHYFLYGFRILPLY 181
+ ++G K G L TY+ +IFK + E F+ + H +GF + L
Sbjct: 114 ----AKLYDNAGKK-------HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLV 162
Query: 182 RCSR-WPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227
+C+ PCPN+VDC+++RPTEK IF FM+ ++V + L + EL +L
Sbjct: 163 QCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 147 bits (371), Expect = 2e-35
Identities = 84/227 (37%), Positives = 124/227 (54%), Gaps = 19/227 (8%)
Query: 6 FLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVC 65
FL +L E + ST +GR+ L VL FR+++L + V+GDEQS+FVC+TQQPGC+ C
Sbjct: 5 FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
Query: 66 YDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYV--RMEEKRKSREAEELGQ-QAGTNG 122
+D P+S +R WV Q+I V+ PS +Y+G +++V E K +E E L Q + G
Sbjct: 65 FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTD 124
Query: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYR 182
P GS++ LL Y+ + + + E + Y LYGF++ +
Sbjct: 125 VPGAGSLR----------------LLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFA 168
Query: 183 CSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGL 229
C R PC + C +SRP+EKTIF+ M V+ L +EL LGL
Sbjct: 169 CRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGL 215
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 146 bits (368), Expect = 4e-35
Identities = 80/223 (35%), Positives = 125/223 (56%), Gaps = 18/223 (8%)
Query: 7 LGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCY 66
LG ++ +N + T++G++W + + R+L++ A V+ DEQ FVCNT QPGC NVCY
Sbjct: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
Query: 67 DEAFPISHIRLWVLQIIFVSTPSL---MYVGHAVHYVRMEEKRKSREAEE--LGQQAGTN 121
D P+SH+R W++Q + V PS +YV H + R+ + E GQ+
Sbjct: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPR 126
Query: 122 GGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLY 181
++G ++ S G YI H++ +TL E F HYFL+GF +
Sbjct: 127 PFGERGGLQVPDFSAG-------------YIIHLLLRTLLEAAFGALHYFLFGFLAPKKF 173
Query: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMEL 224
C+R PC VVDC+VSRPTEK++ +LF+ +V+++S L + +L
Sbjct: 174 PCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADL 216
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 96.3 bits (238), Expect = 5e-20
Identities = 41/86 (47%), Positives = 62/86 (72%)
Query: 10 ILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEA 69
+L E + HST +GR+ VL FR+++L + V+GDEQS+FVC+TQQPGC+ C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISHIRLWVLQIIFVSTPSLMYVGH 95
P+S +R WV Q+I V+ PS++Y+G+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGY 113
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 96.3 bits (238), Expect = 5e-20
Identities = 41/86 (47%), Positives = 62/86 (72%)
Query: 10 ILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEA 69
+L E + HST +GR+ VL FR+++L + V+GDEQS+FVC+TQQPGC+ C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISHIRLWVLQIIFVSTPSLMYVGH 95
P+S +R WV Q+I V+ PS++Y+G+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGY 113
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 96.3 bits (238), Expect = 5e-20
Identities = 41/86 (47%), Positives = 62/86 (72%)
Query: 10 ILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEA 69
+L E + HST +GR+ VL FR+++L + V+GDEQS+FVC+TQQPGC+ C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISHIRLWVLQIIFVSTPSLMYVGH 95
P+S +R WV Q+I V+ PS++Y+G+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGY 113
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,870,665
Number of Sequences: 37866
Number of extensions: 891814
Number of successful extensions: 7596
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 305
Number of HSP's that attempted gapping in prelim test: 5425
Number of HSP's gapped (non-prelim): 1697
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.