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Search of human proteins with 55749769
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
sapiens]
(908 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s... 1804 0.0
gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens] 129 1e-29
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 86 2e-16
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 86 2e-16
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 80 9e-15
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 80 9e-15
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 78 3e-14
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 77 6e-14
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 74 6e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 74 6e-13
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 74 6e-13
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 73 1e-12
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 72 3e-12
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 72 3e-12
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 69 2e-11
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 67 8e-11
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 67 1e-10
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 67 1e-10
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 65 4e-10
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 65 4e-10
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 64 8e-10
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 63 1e-09
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap... 62 2e-09
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 60 1e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 59 2e-08
gi|213385278 TNF receptor-associated factor 3 interacting protei... 59 2e-08
gi|20070262 TNF receptor-associated factor 3 interacting protein... 59 2e-08
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 59 2e-08
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 59 2e-08
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 59 2e-08
>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
sapiens]
Length = 908
Score = 1804 bits (4673), Expect = 0.0
Identities = 908/908 (100%), Positives = 908/908 (100%)
Query: 1 MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGR 60
MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGR
Sbjct: 1 MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGR 60
Query: 61 SYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
SYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD
Sbjct: 61 SYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
Query: 121 ELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISI 180
ELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISI
Sbjct: 121 ELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISI 180
Query: 181 IIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILN 240
IIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILN
Sbjct: 181 IIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILN 240
Query: 241 FRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKEC 300
FRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKEC
Sbjct: 241 FRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKEC 300
Query: 301 GLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLV 360
GLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLV
Sbjct: 301 GLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLDLV 360
Query: 361 EEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAG 420
EEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAG
Sbjct: 361 EEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAG 420
Query: 421 SSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKME 480
SSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKME
Sbjct: 421 SSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKME 480
Query: 481 FPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQYDTIHRLE 540
FPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQYDTIHRLE
Sbjct: 481 FPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGIFKEQYDTIHRLE 540
Query: 541 TNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLN 600
TNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLN
Sbjct: 541 TNKLRNVAKMFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLN 600
Query: 601 ARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPD 660
ARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPD
Sbjct: 601 ARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPD 660
Query: 661 VEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKK 720
VEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKK
Sbjct: 661 VEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKK 720
Query: 721 GHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDP 780
GHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDP
Sbjct: 721 GHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDP 780
Query: 781 ITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRI 840
ITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRI
Sbjct: 781 ITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRI 840
Query: 841 KDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRR 900
KDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRR
Sbjct: 841 KDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRR 900
Query: 901 EKSPAKQK 908
EKSPAKQK
Sbjct: 901 EKSPAKQK 908
>gi|61097912 nucleolar protein with MIF4G domain 1 [Homo sapiens]
Length = 860
Score = 129 bits (324), Expect = 1e-29
Identities = 124/584 (21%), Positives = 241/584 (41%), Gaps = 78/584 (13%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
D + L S +D EE+E D E ++ + ++ E + D E
Sbjct: 241 DAGQTLPESDLESDSQDESEEEEEG------------DVEKEKKAQEAEAQSEDDDEDTE 288
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTGGAYI 134
+ + E++ + R+ R E +S++D T K L +G YI
Sbjct: 289 EEQGEEKEKGAQEKRRGKRV--RFAEDEEKSENSSEDGDITDKS-------LCGSGEKYI 339
Query: 135 PPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGR 194
PP +R +E + K ++ E LKK + GL+N+++ N++ I +L + + R
Sbjct: 340 PP-HVRQAEETVDFK-----KKEELERLKKHVKGLLNRLSEPNMASISGQLEELYMAHSR 393
Query: 195 GLLSRSVLQA-------QSASP---IFTHVYAALVAIINSKFP-QIGELILKRLILNFRK 243
++ ++ A SA P + HV LV+I++ ++G L+ ++ F
Sbjct: 394 KDMNDTLTSALMGACVTASAMPSRLMMEHVL--LVSILHHTVGIEVGAHFLEAVVRKFDA 451
Query: 244 GYRRNDK-QLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGL 302
Y+ + + C +AHL N +V +L ++L L+ T+ +E+ + LK G
Sbjct: 452 IYKYGSEGKECDNLFTVIAHLYNFHVVQSLLIFDILKKLIGTFTEKDIELILLMLKNVGF 511
Query: 303 KLTQVSPRGINAIFERLRNILH----ESEIDKRVQYMIEVMFAVRKDGFKDHPIILEGLD 358
L + + + + E + R+++M+E M A++ + + P
Sbjct: 512 SLRKDDALSLKELITEAQTKASGAGSEFQDQTRIRFMLETMLALKNNDMRKIP------- 564
Query: 359 LVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMEN-----EEKYKAIKKEILDEGDTD- 412
Y+PE V + K+ + N E + + +L T
Sbjct: 565 ----------------GYDPEPVEKLRKLQRALVRNAGSGSETQLRVSWDSVLSAEQTGR 608
Query: 413 ----SNTDQDAGSSEEDEEEEEEEGEEDEEGQKVTIHDKTEINLVSFRRTIYLAIQSSLD 468
+ A + ++ K+ + + RR I+ I +S D
Sbjct: 609 WWIVGSAWSGAPMIDNSHHTHLQKQLVGTVSSKILELARKQRMNTDIRRNIFCTIMTSED 668
Query: 469 FEECAHKLLKMEFPESQTKELCNMILDCCAQQRTYEKFFGLLAGRFCMLKKEYMESFEGI 528
F + KLLK+ + Q +E+ ++++DCC Q++TY F+ LA +FC ++ + +F+
Sbjct: 669 FLDAFEKLLKLGLKDQQEREIIHVLMDCCLQEKTYNPFYAFLASKFCEYERRFQMTFQFS 728
Query: 529 FKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLPWSVLECIKLSE 572
+++ + L N+ + AHLL T SL S+L+ ++ SE
Sbjct: 729 IWDKFRDLENLPATNFSNLVHLVAHLLKTKSLSLSILKVVEFSE 772
Score = 33.9 bits (76), Expect = 0.71
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 8/102 (7%)
Query: 343 RKDGFKDHPIIL--EGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKA 400
+KDG P+ +GLD + + L D E+ + + +E++ + ++
Sbjct: 200 KKDGSSSVPLSFARDGLDYILGALESGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDES 259
Query: 401 IKKEILDEGDTDSNT---DQDAGSSEEDEEEEEEEGEEDEEG 439
++E EGD + + +A S ++DE+ EEE+GEE E+G
Sbjct: 260 EEEE---EGDVEKEKKAQEAEAQSEDDDEDTEEEQGEEKEKG 298
Score = 32.7 bits (73), Expect = 1.6
Identities = 16/49 (32%), Positives = 29/49 (59%)
Query: 393 ENEEKYKAIKKEILDEGDTDSNTDQDAGSSEEDEEEEEEEGEEDEEGQK 441
+N Y + +E D G T +D ++ S +E EEEEE + E++++ Q+
Sbjct: 227 KNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQE 275
Score = 31.6 bits (70), Expect = 3.5
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 6/102 (5%)
Query: 673 SASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDK 732
S +S DSS + + + + S ESDS S + KK E D
Sbjct: 225 SGKNSGLYDSSGEEEEDAGQTLPESDLESDSQDESEEEEEGDVEKEKKAQEAEAQSEDD- 283
Query: 733 LIRNQQTNDRKQKERRQEHGHQETRTERERRSE-KHRDQNSS 773
+ + +Q E +++ ++ R +R R +E + + +NSS
Sbjct: 284 ----DEDTEEEQGEEKEKGAQEKRRGKRVRFAEDEEKSENSS 321
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 85.9 bits (211), Expect = 2e-16
Identities = 75/265 (28%), Positives = 116/265 (43%), Gaps = 22/265 (8%)
Query: 637 GGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSES 696
G + +E + T V+ +K E+ K S S S+SS S S +S + S SS SS S
Sbjct: 476 GDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSS 535
Query: 697 SSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQET 756
S S SS SS SS+ RKK H ++RS + K + R +
Sbjct: 536 YSSSSGSSRTSSRSSSPK---RKKRHSRSRSPTI------------KARRSRSRSYSRRI 580
Query: 757 RTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKH 816
+ E R K RD+ S R+ I + PS SR + RD+ + ++
Sbjct: 581 KIESNRARVKIRDRRRSN---RNSIERERRRNRSPSRERRRSR-SRSRDRRTNRASRSRS 636
Query: 817 GDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSG-SRSDEDRYQNGA 875
D +K +R N + KH K+ E R+K+RS+S + +RK R E +
Sbjct: 637 RDRRKIDDQRGNLSGNSHKHKGEAKEQE--RKKERSRSIDKDRKKKDKEREREQDKRKEK 694
Query: 876 ERRWEKSSRYSEQSRESKKNQDRRR 900
++R EK ++S Q K+ ++ R
Sbjct: 695 QKREEKDFKFSSQDDRLKRKRESER 719
Score = 52.0 bits (123), Expect = 3e-06
Identities = 55/253 (21%), Positives = 106/253 (41%), Gaps = 55/253 (21%)
Query: 682 SSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTND 741
S DS+ + SD SESS + + + +R+K R ++ +L+ ++Q +
Sbjct: 393 SGDSEDERSDRGSESSDTDDEELR---------HRIRQKQEAFWRKEKEQQLLHDKQMEE 443
Query: 742 RKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVA 801
KQ Q R +E H++QNS + +D DV +E+ R
Sbjct: 444 EKQ---------QTERVTKEMNEFIHKEQNSLSL-----LEAREADGDVVNEK---KRTP 486
Query: 802 NDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSE---------------NF 846
N+ + E+K K+K+G R+ S + + + S +
Sbjct: 487 NETTSVLEPKKEHKE---KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS 543
Query: 847 RRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEK-----SSRYSEQSRESKKN------ 895
R RS S + ++HS SRS + + R + + S+R + R+ +++
Sbjct: 544 RTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE 603
Query: 896 QDRRREKSPAKQK 908
++RRR +SP++++
Sbjct: 604 RERRRNRSPSRER 616
Score = 49.7 bits (117), Expect = 1e-05
Identities = 68/269 (25%), Positives = 105/269 (39%), Gaps = 40/269 (14%)
Query: 666 SSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKT 725
SS SS ++S SS S S S + S S S S +N R K +
Sbjct: 538 SSSGSSRTSSRSSSPKRKKRHSRS--RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRR 595
Query: 726 RSKEVDKLIRNQQTNDRKQKERRQEHGH-QETRTERERRS--------EKHRDQNSSGSN 776
RS + + R ++ N +ERR+ ++ RT R RS + R S S+
Sbjct: 596 RSNR-NSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH 654
Query: 777 WRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
K K S + R D+++E D + K+KR E+ FS +
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFKFSSQDDR 710
Query: 837 THRIKDSEN------------FRRKDRSKSKEM----NRKHSGS----RSDEDRYQNGAE 876
R ++SE R R SK+ ++KHSGS RS + + E
Sbjct: 711 LKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKE 770
Query: 877 RRWEK----SSRYSEQSRESKKNQDRRRE 901
++ +K SR E+S+ S K R+ +
Sbjct: 771 KKAKKPKHSRSRSVEKSQRSGKKASRKHK 799
Score = 39.7 bits (91), Expect = 0.013
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 16 RRENLNSYQR----NSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRR---------GRSY 62
RR N NS +R N SP RDR SRS R+ G S+
Sbjct: 595 RRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH 654
Query: 63 DSSMESRNRDREKRRERERDTDRK-----RSRKSPSPGRRNPETSVTQSSSAQDEPATKK 117
E++ ++R+K R R D DRK R R+ + S+QD+ +K
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRK 714
Query: 118 KKDE 121
++ E
Sbjct: 715 RESE 718
Score = 37.0 bits (84), Expect = 0.083
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 663 QNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSI---SSHSSASANDVRK 719
+ +S + S S S S + DS DS S+++ S + S S S SS S S+ + +
Sbjct: 714 KRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKA 773
Query: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKER 747
K +RS+ V+K R+ + RK K +
Sbjct: 774 KKPKHSRSRSVEKSQRSGKKASRKHKSK 801
Score = 33.9 bits (76), Expect = 0.71
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 13/106 (12%)
Query: 4 SVAQIKPSSGHDRRENLNSYQRNSSPEDRYEE---QERSPRDRDY-----FDYSRSDYEH 55
S + SSG R + +S + R + R R R Y + +R+ +
Sbjct: 532 SSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKI 591
Query: 56 SRRGRSYDSSME-----SRNRDREKRRERERDTDRKRSRKSPSPGR 96
R RS +S+E +R+ RE+RR R R DR+ +R S S R
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSR 637
Score = 33.1 bits (74), Expect = 1.2
Identities = 30/138 (21%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 15 DRRENL--NSYQRNSSPEDRYEEQERS---PRDRDYFDYSRSDYEHSRRGRSYDSSMESR 69
D+R NL NS++ +++ ++ERS +DR D R + R+ + + +
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703
Query: 70 NRDREKRRERERDTDRKRSRKSP-------SPGRRNPETSVTQSS-----------SAQD 111
++ R +R+R+++R SR R++ + S T+ S S+ +
Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763
Query: 112 EPATKKKKDELDPLLTRT 129
P + K+K P +R+
Sbjct: 764 SPGSSKEKKAKKPKHSRS 781
Score = 32.7 bits (73), Expect = 1.6
Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)
Query: 21 NSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESR---NRDREKRR 77
+S +SS R + SP+ + SRS +RR RS S + NR R K R
Sbjct: 533 SSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR 592
Query: 78 ERER------DTDRKRSRKSPSPGRR 97
+R R + +R+R+R SPS RR
Sbjct: 593 DRRRSNRNSIERERRRNR-SPSRERR 617
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 85.9 bits (211), Expect = 2e-16
Identities = 75/265 (28%), Positives = 116/265 (43%), Gaps = 22/265 (8%)
Query: 637 GGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSES 696
G + +E + T V+ +K E+ K S S S+SS S S +S + S SS SS S
Sbjct: 476 GDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSS 535
Query: 697 SSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQET 756
S S SS SS SS+ RKK H ++RS + K + R +
Sbjct: 536 YSSSSGSSRTSSRSSSPK---RKKRHSRSRSPTI------------KARRSRSRSYSRRI 580
Query: 757 RTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKH 816
+ E R K RD+ S R+ I + PS SR + RD+ + ++
Sbjct: 581 KIESNRARVKIRDRRRSN---RNSIERERRRNRSPSRERRRSR-SRSRDRRTNRASRSRS 636
Query: 817 GDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSG-SRSDEDRYQNGA 875
D +K +R N + KH K+ E R+K+RS+S + +RK R E +
Sbjct: 637 RDRRKIDDQRGNLSGNSHKHKGEAKEQE--RKKERSRSIDKDRKKKDKEREREQDKRKEK 694
Query: 876 ERRWEKSSRYSEQSRESKKNQDRRR 900
++R EK ++S Q K+ ++ R
Sbjct: 695 QKREEKDFKFSSQDDRLKRKRESER 719
Score = 52.0 bits (123), Expect = 3e-06
Identities = 55/253 (21%), Positives = 106/253 (41%), Gaps = 55/253 (21%)
Query: 682 SSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTND 741
S DS+ + SD SESS + + + +R+K R ++ +L+ ++Q +
Sbjct: 393 SGDSEDERSDRGSESSDTDDEELR---------HRIRQKQEAFWRKEKEQQLLHDKQMEE 443
Query: 742 RKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVA 801
KQ Q R +E H++QNS + +D DV +E+ R
Sbjct: 444 EKQ---------QTERVTKEMNEFIHKEQNSLSL-----LEAREADGDVVNEK---KRTP 486
Query: 802 NDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSE---------------NF 846
N+ + E+K K+K+G R+ S + + + S +
Sbjct: 487 NETTSVLEPKKEHKE---KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS 543
Query: 847 RRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEK-----SSRYSEQSRESKKN------ 895
R RS S + ++HS SRS + + R + + S+R + R+ +++
Sbjct: 544 RTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE 603
Query: 896 QDRRREKSPAKQK 908
++RRR +SP++++
Sbjct: 604 RERRRNRSPSRER 616
Score = 49.7 bits (117), Expect = 1e-05
Identities = 68/269 (25%), Positives = 105/269 (39%), Gaps = 40/269 (14%)
Query: 666 SSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKT 725
SS SS ++S SS S S S + S S S S +N R K +
Sbjct: 538 SSSGSSRTSSRSSSPKRKKRHSRS--RSPTIKARRSRSRSYSRRIKIESNRARVKIRDRR 595
Query: 726 RSKEVDKLIRNQQTNDRKQKERRQEHGH-QETRTERERRS--------EKHRDQNSSGSN 776
RS + + R ++ N +ERR+ ++ RT R RS + R S S+
Sbjct: 596 RSNR-NSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH 654
Query: 777 WRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
K K S + R D+++E D + K+KR E+ FS +
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFKFSSQDDR 710
Query: 837 THRIKDSEN------------FRRKDRSKSKEM----NRKHSGS----RSDEDRYQNGAE 876
R ++SE R R SK+ ++KHSGS RS + + E
Sbjct: 711 LKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKE 770
Query: 877 RRWEK----SSRYSEQSRESKKNQDRRRE 901
++ +K SR E+S+ S K R+ +
Sbjct: 771 KKAKKPKHSRSRSVEKSQRSGKKASRKHK 799
Score = 39.7 bits (91), Expect = 0.013
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 18/124 (14%)
Query: 16 RRENLNSYQR----NSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRR---------GRSY 62
RR N NS +R N SP RDR SRS R+ G S+
Sbjct: 595 RRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH 654
Query: 63 DSSMESRNRDREKRRERERDTDRK-----RSRKSPSPGRRNPETSVTQSSSAQDEPATKK 117
E++ ++R+K R R D DRK R R+ + S+QD+ +K
Sbjct: 655 KHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRK 714
Query: 118 KKDE 121
++ E
Sbjct: 715 RESE 718
Score = 37.0 bits (84), Expect = 0.083
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 663 QNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSI---SSHSSASANDVRK 719
+ +S + S S S S + DS DS S+++ S + S S S SS S S+ + +
Sbjct: 714 KRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKA 773
Query: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKER 747
K +RS+ V+K R+ + RK K +
Sbjct: 774 KKPKHSRSRSVEKSQRSGKKASRKHKSK 801
Score = 33.9 bits (76), Expect = 0.71
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 13/106 (12%)
Query: 4 SVAQIKPSSGHDRRENLNSYQRNSSPEDRYEE---QERSPRDRDY-----FDYSRSDYEH 55
S + SSG R + +S + R + R R R Y + +R+ +
Sbjct: 532 SSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKI 591
Query: 56 SRRGRSYDSSME-----SRNRDREKRRERERDTDRKRSRKSPSPGR 96
R RS +S+E +R+ RE+RR R R DR+ +R S S R
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSR 637
Score = 33.1 bits (74), Expect = 1.2
Identities = 30/138 (21%), Positives = 61/138 (44%), Gaps = 23/138 (16%)
Query: 15 DRRENL--NSYQRNSSPEDRYEEQERS---PRDRDYFDYSRSDYEHSRRGRSYDSSMESR 69
D+R NL NS++ +++ ++ERS +DR D R + R+ + + +
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703
Query: 70 NRDREKRRERERDTDRKRSRKSP-------SPGRRNPETSVTQSS-----------SAQD 111
++ R +R+R+++R SR R++ + S T+ S S+ +
Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763
Query: 112 EPATKKKKDELDPLLTRT 129
P + K+K P +R+
Sbjct: 764 SPGSSKEKKAKKPKHSRS 781
Score = 32.7 bits (73), Expect = 1.6
Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)
Query: 21 NSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESR---NRDREKRR 77
+S +SS R + SP+ + SRS +RR RS S + NR R K R
Sbjct: 533 SSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR 592
Query: 78 ERER------DTDRKRSRKSPSPGRR 97
+R R + +R+R+R SPS RR
Sbjct: 593 DRRRSNRNSIERERRRNR-SPSRERR 617
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 80.1 bits (196), Expect = 9e-15
Identities = 55/248 (22%), Positives = 103/248 (41%), Gaps = 7/248 (2%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
+ K + +S S + + S S D S S S E S SHS
Sbjct: 319 SSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 378
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
D R+K K R KE D+ ++ +R++++ R ++ ++ E++R +K +D+
Sbjct: 379 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE---- 434
Query: 776 NWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEK 835
R+ ++ D+D E+ ++D+ ID E + D K + R + S +
Sbjct: 435 --REREKEHEKDRDKEKEKEQDKEKEREKDRSKEID-EKRKKDKKSRTPPRSYNASRRSR 491
Query: 836 HTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKN 895
+ R + R RS K SRS R +N +++ EK + + RE +++
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Query: 896 QDRRREKS 903
R+ +
Sbjct: 552 TSMRKSSN 559
Score = 73.2 bits (178), Expect = 1e-12
Identities = 65/267 (24%), Positives = 114/267 (42%), Gaps = 20/267 (7%)
Query: 650 TPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSH 709
TP+ + +V + S SA+ ES S+ + S S + S+ SS S
Sbjct: 267 TPQAAAKELEEVMKRVREAQSFISAAIEPESGKSN-ERKGGRSRSHTRSKSRSSSKSHSR 325
Query: 710 SSASANDVRKKGHGKTRSKEVDKLIRNQQTNDR-KQKERRQEHGHQETRT---------- 758
S + R + H ++RS++ D+ R K +ERR+ +R
Sbjct: 326 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 385
Query: 759 ERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGD 818
E+ER EK R++ R+ + +KD ER ++D+E + E++
Sbjct: 386 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 445
Query: 819 PKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERR 878
K+K E+ E E+ R K+ + +RK KS+ R ++ SR R ++ + R
Sbjct: 446 DKEKEKEQDK---EKEREKDRSKEIDE-KRKKDKKSRTPPRSYNASR----RSRSSSRER 497
Query: 879 WEKSSRYSEQSRESKKNQDRRREKSPA 905
+ SR S +S + K R+ +SP+
Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPS 524
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/237 (19%), Positives = 89/237 (37%), Gaps = 14/237 (5%)
Query: 642 ELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEES 701
+ RE +K +V + + + + + D D + E
Sbjct: 379 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 438
Query: 702 DSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERE 761
++K K RSKE+D+ RK+ ++ + + R
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE--------KRKKDKKSRTPPRSYNASRRS 490
Query: 762 RRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHID-----LENKH 816
R S + R + S S+ R P T T + + SR D+ +E D E +
Sbjct: 491 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERER 550
Query: 817 GDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQN 873
+K R+ + EK++ +K+ E+ + D S SKE++ K R++E++ Q+
Sbjct: 551 STSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK-DAPRTEENKIQH 606
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/113 (23%), Positives = 49/113 (43%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K S +RR++ + +D E+ + R ++ + E R +
Sbjct: 357 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 416
Query: 69 RNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
R+++REK RE++++ DR+R R+ R+ E Q + E K+ DE
Sbjct: 417 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 11/118 (9%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERS-PRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDR 73
DR + + +DR E+E+ +DRD D E R E R +D+
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475
Query: 74 EKR--------RERERDTDRKRSRKSPSPGRRNPETSVT--QSSSAQDEPATKKKKDE 121
+ R R R + R+R R+ R+P TS T + SS P ++ KKD+
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/117 (19%), Positives = 49/117 (41%)
Query: 792 SERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDR 851
S ++N + R + ++KR + ++ + + R KD + +
Sbjct: 297 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 356
Query: 852 SKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+SK R+ S SRS + + ++ R E+ RE ++ +++ REK + K
Sbjct: 357 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413
Score = 40.8 bits (94), Expect = 0.006
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
Query: 11 SSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRN 70
S H RR+ S R+ S +R +++ R RS R+ RS S + R
Sbjct: 320 SKSHSRRKRSQSKHRSRS-HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 378
Query: 71 RDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
REK +E+ER ++ R ++ R E ++ E ++KD+
Sbjct: 379 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 429
Score = 40.4 bits (93), Expect = 0.008
Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 813 ENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKS----KEMNRKHSGSRSDE 868
++KH R R K H+ + RRK RS+S K + + +
Sbjct: 330 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 869 DRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ ++ + R + R E+ R K++D+ REK K K
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 429
Score = 37.7 bits (86), Expect = 0.049
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 10/92 (10%)
Query: 29 PEDRYEEQERSPRDRDYF-DYSRSDYE-HSRRGRSYDSSMESRNRDREKRRERERDTDRK 86
PE + + R R + SRS + HSRR RS +S++R R R R R DR+
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS-----QSKHRSRSHNRSRSRQKDRR 349
Query: 87 RSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
RS+ SP ++ ++ + S ++ K+K
Sbjct: 350 RSK---SPHKKRSKSRERRKSRSRSHSRDKRK 378
Score = 35.0 bits (79), Expect = 0.32
Identities = 34/130 (26%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQE---RSPRDRDYFDYSRSDYEHSRRGRSYDSS 65
K S R N + R+SS E R RSPR +S S R R+
Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK-RKSSRSPSPRSRNKKDK 533
Query: 66 MESRNRDR-EKRRERERDTDRKRSRK---------------SPSPGRRNPETSVTQSSSA 109
+ RD +RRERER T ++S + P++SV++
Sbjct: 534 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 593
Query: 110 QDEPATKKKK 119
+D P T++ K
Sbjct: 594 KDAPRTEENK 603
Score = 34.3 bits (77), Expect = 0.54
Identities = 26/122 (21%), Positives = 50/122 (40%), Gaps = 16/122 (13%)
Query: 6 AQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSS 65
A I+P SG + ++ + R + S R R + R RS++ S
Sbjct: 291 AAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS---------QSKHRSRSHNRS 341
Query: 66 MESRNRDR------EKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
SR +DR K+R + R+ + RSR R++ + + +++ K+++
Sbjct: 342 -RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 400
Query: 120 DE 121
E
Sbjct: 401 RE 402
Score = 33.5 bits (75), Expect = 0.92
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 2/124 (1%)
Query: 2 KSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRS 61
K +I D++ N+S R +ER R S + +R S
Sbjct: 461 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 520
Query: 62 YDSSMESRNRDREKRRERERD-TDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
S SRN+ ++K+RE+ERD +R R+ + R++ + ++ + K+K+
Sbjct: 521 RSPSPRSRNK-KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 579
Query: 121 ELDP 124
+P
Sbjct: 580 NKEP 583
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 80.1 bits (196), Expect = 9e-15
Identities = 55/248 (22%), Positives = 103/248 (41%), Gaps = 7/248 (2%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
+ K + +S S + + S S D S S S E S SHS
Sbjct: 203 SSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 262
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
D R+K K R KE D+ ++ +R++++ R ++ ++ E++R +K +D+
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE---- 318
Query: 776 NWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEK 835
R+ ++ D+D E+ ++D+ ID E + D K + R + S +
Sbjct: 319 --REREKEHEKDRDKEKEKEQDKEKEREKDRSKEID-EKRKKDKKSRTPPRSYNASRRSR 375
Query: 836 HTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKN 895
+ R + R RS K SRS R +N +++ EK + + RE +++
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Query: 896 QDRRREKS 903
R+ +
Sbjct: 436 TSMRKSSN 443
Score = 73.2 bits (178), Expect = 1e-12
Identities = 65/267 (24%), Positives = 114/267 (42%), Gaps = 20/267 (7%)
Query: 650 TPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSH 709
TP+ + +V + S SA+ ES S+ + S S + S+ SS S
Sbjct: 151 TPQAAAKELEEVMKRVREAQSFISAAIEPESGKSN-ERKGGRSRSHTRSKSRSSSKSHSR 209
Query: 710 SSASANDVRKKGHGKTRSKEVDKLIRNQQTNDR-KQKERRQEHGHQETRT---------- 758
S + R + H ++RS++ D+ R K +ERR+ +R
Sbjct: 210 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 269
Query: 759 ERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGD 818
E+ER EK R++ R+ + +KD ER ++D+E + E++
Sbjct: 270 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 329
Query: 819 PKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERR 878
K+K E+ E E+ R K+ + +RK KS+ R ++ SR R ++ + R
Sbjct: 330 DKEKEKEQDK---EKEREKDRSKEIDE-KRKKDKKSRTPPRSYNASR----RSRSSSRER 381
Query: 879 WEKSSRYSEQSRESKKNQDRRREKSPA 905
+ SR S +S + K R+ +SP+
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPS 408
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/237 (19%), Positives = 89/237 (37%), Gaps = 14/237 (5%)
Query: 642 ELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEES 701
+ RE +K +V + + + + + D D + E
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 322
Query: 702 DSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERE 761
++K K RSKE+D+ RK+ ++ + + R
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE--------KRKKDKKSRTPPRSYNASRRS 374
Query: 762 RRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHID-----LENKH 816
R S + R + S S+ R P T T + + SR D+ +E D E +
Sbjct: 375 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERER 434
Query: 817 GDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQN 873
+K R+ + EK++ +K+ E+ + D S SKE++ K R++E++ Q+
Sbjct: 435 STSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK-DAPRTEENKIQH 490
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/113 (23%), Positives = 49/113 (43%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K S +RR++ + +D E+ + R ++ + E R +
Sbjct: 241 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 300
Query: 69 RNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
R+++REK RE++++ DR+R R+ R+ E Q + E K+ DE
Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 11/118 (9%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERS-PRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDR 73
DR + + +DR E+E+ +DRD D E R E R +D+
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Query: 74 EKR--------RERERDTDRKRSRKSPSPGRRNPETSVT--QSSSAQDEPATKKKKDE 121
+ R R R + R+R R+ R+P TS T + SS P ++ KKD+
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/117 (19%), Positives = 49/117 (41%)
Query: 792 SERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDR 851
S ++N + R + ++KR + ++ + + R KD + +
Sbjct: 181 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 240
Query: 852 SKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+SK R+ S SRS + + ++ R E+ RE ++ +++ REK + K
Sbjct: 241 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297
Score = 40.8 bits (94), Expect = 0.006
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 1/111 (0%)
Query: 11 SSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRN 70
S H RR+ S R+ S +R +++ R RS R+ RS S + R
Sbjct: 204 SKSHSRRKRSQSKHRSRS-HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK 262
Query: 71 RDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
REK +E+ER ++ R ++ R E ++ E ++KD+
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 313
Score = 40.4 bits (93), Expect = 0.008
Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 813 ENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKS----KEMNRKHSGSRSDE 868
++KH R R K H+ + RRK RS+S K + + +
Sbjct: 214 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 869 DRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ ++ + R + R E+ R K++D+ REK K K
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 313
Score = 37.7 bits (86), Expect = 0.049
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 10/92 (10%)
Query: 29 PEDRYEEQERSPRDRDYF-DYSRSDYE-HSRRGRSYDSSMESRNRDREKRRERERDTDRK 86
PE + + R R + SRS + HSRR RS +S++R R R R R DR+
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS-----QSKHRSRSHNRSRSRQKDRR 233
Query: 87 RSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
RS+ SP ++ ++ + S ++ K+K
Sbjct: 234 RSK---SPHKKRSKSRERRKSRSRSHSRDKRK 262
Score = 35.0 bits (79), Expect = 0.32
Identities = 34/130 (26%), Positives = 50/130 (38%), Gaps = 20/130 (15%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQE---RSPRDRDYFDYSRSDYEHSRRGRSYDSS 65
K S R N + R+SS E R RSPR +S S R R+
Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK-RKSSRSPSPRSRNKKDK 417
Query: 66 MESRNRDR-EKRRERERDTDRKRSRK---------------SPSPGRRNPETSVTQSSSA 109
+ RD +RRERER T ++S + P++SV++
Sbjct: 418 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 477
Query: 110 QDEPATKKKK 119
+D P T++ K
Sbjct: 478 KDAPRTEENK 487
Score = 34.3 bits (77), Expect = 0.54
Identities = 26/122 (21%), Positives = 50/122 (40%), Gaps = 16/122 (13%)
Query: 6 AQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSS 65
A I+P SG + ++ + R + S R R + R RS++ S
Sbjct: 175 AAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS---------QSKHRSRSHNRS 225
Query: 66 MESRNRDR------EKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
SR +DR K+R + R+ + RSR R++ + + +++ K+++
Sbjct: 226 -RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 284
Query: 120 DE 121
E
Sbjct: 285 RE 286
Score = 33.5 bits (75), Expect = 0.92
Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 2/124 (1%)
Query: 2 KSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRS 61
K +I D++ N+S R +ER R S + +R S
Sbjct: 345 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 404
Query: 62 YDSSMESRNRDREKRRERERD-TDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
S SRN+ ++K+RE+ERD +R R+ + R++ + ++ + K+K+
Sbjct: 405 RSPSPRSRNK-KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 463
Query: 121 ELDP 124
+P
Sbjct: 464 NKEP 467
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 78.2 bits (191), Expect = 3e-14
Identities = 64/239 (26%), Positives = 93/239 (38%), Gaps = 2/239 (0%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDS-DSDSSDSSSESSSEESDSSSISSHSSASANDVR 718
D + SS S+SSS S SS+SDSSDS DSDSSDSS+ S S +S SS SS SS S++
Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624
Query: 719 KKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWR 778
++ S + D + +N + + + +SS S+
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 779 DPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTH 838
+ S S ++ S ++D D D N + +S S N +
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 839 RIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
DS N S S N S SD + + S S S +S + D
Sbjct: 745 DSSDSSNSSDSSDS-SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Score = 75.1 bits (183), Expect = 3e-13
Identities = 64/239 (26%), Positives = 92/239 (38%), Gaps = 6/239 (2%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDS-DSDSSDSSSESSSEESDSSSISSHSSASANDVR 718
D + S SS+S+ SS+ SDSSDS DS SDSS+ S S S SS SS+SS S++
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Query: 719 KKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWR 778
+ S + ++D + E S+ NSS S+
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906
Query: 779 DPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTH 838
D + +SD S ++ S +N D D N D +S S N +
Sbjct: 907 D--SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS-SDSSDSSDSSNSSDSSNSSDSS 963
Query: 839 RIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
DS + D S S N S SD + ++ S S S +S + D
Sbjct: 964 NSSDSSDSNSSDSSDSS--NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Score = 74.3 bits (181), Expect = 5e-13
Identities = 63/243 (25%), Positives = 99/243 (40%), Gaps = 6/243 (2%)
Query: 658 KPDVEQNKSSPSSSSSASSSSESDSSD-SDSDSSD--SSSESSSEESDSSSISSHSSASA 714
K D + KS S S S+ SS+ SDSSD SDSDSSD SSS+S S +SDSS S S+ +
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS 598
Query: 715 NDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSG 774
++ S D + +D + E ++ + S+ + +SS
Sbjct: 599 SNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD 658
Query: 775 SNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENE 834
S+ + +SD S+ ++ S +N D D N +S ++
Sbjct: 659 SS-NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717
Query: 835 KHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKK 894
DS++ D S S N S SD + ++ +S S S +S
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSS--NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 895 NQD 897
+ D
Sbjct: 776 SSD 778
Score = 71.2 bits (173), Expect = 4e-12
Identities = 56/241 (23%), Positives = 93/241 (38%), Gaps = 7/241 (2%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSD--SDSSDSSSESSSEESDSSSISSHSSASANDV 717
D + S SS S++SS SDSSDS SDSS+SS + S S SS SS+SS S+N
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW 777
+ + + ++D + ++ +R +S+ S+
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Query: 778 RDPI-TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
D + +SD S+ N S ++ D D ++ + NS +E
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927
Query: 837 THRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQ 896
S+N D S S + + S S + + + + S S S +S +
Sbjct: 928 ----NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 897 D 897
D
Sbjct: 984 D 984
Score = 69.7 bits (169), Expect = 1e-11
Identities = 59/242 (24%), Positives = 103/242 (42%), Gaps = 7/242 (2%)
Query: 662 EQNKSSPSSSSSASSSSESDSSDSD----SDSSDSSSES-SSEESDSSSISSHSSASAND 716
+ + SS S SS +S SS S+SSDSD SDSSDSS+ S SS+ SDSS+ S S +S +
Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762
Query: 717 VRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSN 776
+ S + + +ND + + + S+ +S SN
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 777 WRDPI-TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEK 835
D + +SD S+ ++ S ++ D + ++ + + NS S++
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS-SDSSD 881
Query: 836 HTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKN 895
+ + S + D S S + + S + SD N ++ +S + S +S +
Sbjct: 882 SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941
Query: 896 QD 897
D
Sbjct: 942 SD 943
Score = 69.3 bits (168), Expect = 2e-11
Identities = 69/253 (27%), Positives = 103/253 (40%), Gaps = 20/253 (7%)
Query: 658 KPDVEQNKSSPSSSSSASSSSESDSSDSD-----SDSSDSSSESSSEESDSSSISSHSSA 712
K D +++S S S S S SS+S+SSDS SDSS+SS+ S S +S SS SS SS
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682
Query: 713 SAN--DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQ 770
S+N D S+ D + ++D + + ++ S+
Sbjct: 683 SSNSSDSSDSSDSSNSSESSD----SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Query: 771 NSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSF 830
NSS S+ + +SD S+ +N S ++ D D N D +S
Sbjct: 739 NSSDSS-DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-SDSNDSSNSSDSSD 796
Query: 831 SENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSR 890
S N + DS + D S S N S + SD N ++ SS S+ S
Sbjct: 797 SSNSSDSSNSSDSSD--SSDSSDSDSSNSSDSSNSSDSSDSSNSSD-----SSDSSDSSD 849
Query: 891 ESKKNQDRRREKS 903
S + R + S
Sbjct: 850 GSDSDSSNRSDSS 862
Score = 69.3 bits (168), Expect = 2e-11
Identities = 56/244 (22%), Positives = 87/244 (35%), Gaps = 6/244 (2%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
+ + D + S SS S++SS SDSSDS+ S+ S S SS SDS S S +S+ ++
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
D S D N ++D + ++ S+ +SS S
Sbjct: 916 DSSNSSDSSESSNSSD----NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971
Query: 776 NWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEK 835
N D S S ++ S ++D + D +S S N
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 836 HTHRIKDSENFRRKDRS--KSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESK 893
+ DS + S S N S SD + ++ S S S +S
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091
Query: 894 KNQD 897
+ D
Sbjct: 1092 NSSD 1095
Score = 67.8 bits (164), Expect = 4e-11
Identities = 50/234 (21%), Positives = 89/234 (38%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHG 723
N S S SS +S SS+S +S +DSS+SS S S S SS SS SS S++
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 724 KTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITK 783
+ S + ++D + ++ + + +S SN D
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 784 YTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDS 843
S++ S ++ S ++D D + + ++ S+N + S
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 844 ENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
++ D S S + + S S + N ++ +S S S +S + D
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996
Score = 67.8 bits (164), Expect = 4e-11
Identities = 57/235 (24%), Positives = 93/235 (39%), Gaps = 8/235 (3%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHG 723
+ S SS+S+ SS+ SDSSDS + S S S SS+ SDS S + S++++D
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 724 KTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITK 783
S D N+ +N + + ++ S+ NSS S+ +
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSD--SSNSSDSDSSDSSNSSDSSDSSNSSDSS----ESS 927
Query: 784 YTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDS 843
+SD S+ +N S ++ D D N NS S++ ++ S
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS-SDSSDSSNSSDSS 986
Query: 844 ENFRRKDRSKSKE-MNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
++ D S S + N S SD N ++ S S S +S + D
Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Score = 66.2 bits (160), Expect = 1e-10
Identities = 62/253 (24%), Positives = 95/253 (37%), Gaps = 13/253 (5%)
Query: 664 NKSSPSSSSSASSSSESDSSDS-----DSDSSDSSSESSSEESDSSSISSHSSAS----- 713
+ S +SS S+ SS+ SDSSDS SDSSDSS S+S +S SS SS SS S
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 714 ANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRD--QN 771
+ND S D + ++ + + + + S D +
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 772 SSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDL-ENKHGDPKKKRGERRNSF 830
S S+ D + SD S+ ++ S +N D D E+ + +S
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 831 SENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSR 890
S + ++ DS N S + N S S + D + SS S+ S
Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 891 ESKKNQDRRREKS 903
S + + S
Sbjct: 965 SSDSSDSNSSDSS 977
Score = 65.1 bits (157), Expect = 3e-10
Identities = 51/244 (20%), Positives = 92/244 (37%), Gaps = 2/244 (0%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRK 719
D + S +SS S+ SS SDS SDS S +S+ S S+ S+SS S S++S +
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747
Query: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRD 779
+ S + + ++D + + + S+ NSS S+
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807
Query: 780 PITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHR 839
+ + D S ++ S ++D + + D ++ S++ +
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Query: 840 IKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRR 899
S++ D S S + N S + SD N ++ SS S+ S S +
Sbjct: 868 SDSSDSSNSSDSSDSSDSN--ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 900 REKS 903
S
Sbjct: 926 SSNS 929
Score = 65.1 bits (157), Expect = 3e-10
Identities = 61/236 (25%), Positives = 92/236 (38%), Gaps = 11/236 (4%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHG 723
N S S SS++S S SDSS+S SDSSDSS+ S S ES +SS +S+SS S+N
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNS-SDSSDSSNSSDSSESSNSSDNSNSSDSSNS-SDSSDS 947
Query: 724 KTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRD--QNSSGSNWRDPI 781
S D + +N + + + S D +S SN D
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD-- 1005
Query: 782 TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIK 841
+SD S+ +N S +N D D + + S++ +
Sbjct: 1006 ---SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 842 DSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
S++ D S S + + S SD N ++ S S S +S + D
Sbjct: 1063 SSDSSDSSDSSDSSDSS--DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116
Score = 65.1 bits (157), Expect = 3e-10
Identities = 56/244 (22%), Positives = 100/244 (40%), Gaps = 7/244 (2%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDS--DSDSSDSSSESSSEESDSSSISSHSSASANDV 717
D + +S SS S++SS S+SSDS SDSSDSS S+S +S +SS SS+SS S++
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW 777
+ S + + ++D + ++ S+ +SS S+
Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS- 1031
Query: 778 RDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHT 837
+ +SD S+ ++ S +N D D + + S++ +
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091
Query: 838 HRIKDSENFRRKDRSKSKE----MNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESK 893
+ S++ D S S + + S + SD + ++ +S S S ES
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 894 KNQD 897
+ D
Sbjct: 1152 DSSD 1155
Score = 65.1 bits (157), Expect = 3e-10
Identities = 61/237 (25%), Positives = 92/237 (38%), Gaps = 5/237 (2%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSD-SDSSDSSSESSSEESDSSSISSHSSASAN--D 716
D + +S SS+S+ SS+ SDSSDS+ SDSSDSS+ S S +S SS SS SS S+N D
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 717 VRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSN 776
S D + +N + ++ + + +S S+
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Query: 777 WRDPI-TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEK 835
D + +SD SE ++ S +N D D + D +S S N
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD-SSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 836 HTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRES 892
+ DS + S + + S S D + SS S+ S S
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Score = 64.7 bits (156), Expect = 4e-10
Identities = 54/240 (22%), Positives = 88/240 (36%), Gaps = 3/240 (1%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRK 719
D N ++ + + S S + S SDSDSSDSS+ S S +S S S +S+S +D
Sbjct: 525 DSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD 584
Query: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRD 779
+ + + ++D + +SE + S S+ D
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD 644
Query: 780 PITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHR 839
+ +SD S+ +N S ++ D D + D +S S N +
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD-SSSSSDSSNSSDSSDSSDSSNSSESSD 703
Query: 840 IKDSENFRRKDRSKSKEMNRKHSGS--RSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
DS + D S S N S S SD N ++ S S S +S + +
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763
Score = 64.7 bits (156), Expect = 4e-10
Identities = 56/239 (23%), Positives = 90/239 (37%), Gaps = 8/239 (3%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSS-SESSSEESDSSSISSHSSASANDVR 718
D + +S SS S+ SS SDSSDS SDSS SES S +SDS S SS S++S +
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653
Query: 719 KKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWR 778
+ S + ++D ++ SE +SS S+
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Query: 779 DPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTH 838
D +SD + ++ S ++D + + D +S S N +
Sbjct: 714 D-----SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 839 RIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
DS + D S S + N + S S + + + + S +S + D
Sbjct: 769 DSSDSSD--SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Score = 64.7 bits (156), Expect = 4e-10
Identities = 54/237 (22%), Positives = 90/237 (37%), Gaps = 9/237 (3%)
Query: 662 EQNKSSPSSSSSASSSSESDSSDSDSDSSDSS-SESSSEESDSSSISSHSSASANDVRKK 720
+ + S+ S SS++S SS+S S + SDSSDSS S SS SDSS S+ S + ++D
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS 911
Query: 721 GHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDP 780
S D ++ +N ++ + + +S SN D
Sbjct: 912 SDSSDSSNSSDS---SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 781 ITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRI 840
+SD S ++ S ++ D D N ++ S++ +
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 841 KDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
S++ D S S + S SD N ++ S S S +S + D
Sbjct: 1029 NSSDSSDSSDSSDSSD-----SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Score = 63.9 bits (154), Expect = 6e-10
Identities = 58/215 (26%), Positives = 93/215 (43%), Gaps = 9/215 (4%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
++ D + +S SS S+ SS SDSSDS SDSSDSS S+S +S SS SS SS S+N
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
+ S + + ++D + ++ S+ +SS S
Sbjct: 1141 S--SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 776 NWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEK 835
+ + +SD S+ ++ S ++ D D N+ D +S S +
Sbjct: 1199 S----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-SNESSDSSDSSDSSDSSNSSDSS 1253
Query: 836 HTHRIKDS-ENFRRKDRSKSKEMNRKHSGSRSDED 869
+ DS + + S+SK N ++GS SD D
Sbjct: 1254 DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288
Score = 61.6 bits (148), Expect = 3e-09
Identities = 56/235 (23%), Positives = 95/235 (40%), Gaps = 11/235 (4%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDSDSSDSSSES-SSEESDSSSISSHSSASANDVRKKGH 722
N S S SS++S SSES +S +S+SSDSS+ S SS+ SDSS+ SS SS S++
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN-SSDSSNSSDSSNSSDS 968
Query: 723 GKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPIT 782
+ S + + ++D + ++ S+ NSS S+
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS------ 1022
Query: 783 KYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKD 842
+SD S+ ++ S ++ D D + + S++ +
Sbjct: 1023 -NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 843 SENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
SE+ D S S + + S SD + ++ S S S +S + D
Sbjct: 1082 SESSDSSDSSNSSDSS--DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Score = 60.8 bits (146), Expect = 5e-09
Identities = 56/235 (23%), Positives = 98/235 (41%), Gaps = 6/235 (2%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHG 723
+ S+ S S S+ SS+ SDSSDS S+SSDSS S+S ++ +SS SS+SS S +D +
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDS-SNSSDSSESSNSSDNSNSSDSSNSSDS-SDSSDSSNS 953
Query: 724 KTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITK 783
S D + ++D + ++ + +S+ S+ D +
Sbjct: 954 SDSSNSSDS-SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD--SS 1010
Query: 784 YTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDS 843
+SD S+ +N S +N D D + ++ S++ + S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 844 ENFRRKDRSKSKE-MNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
++ D S S E + S + SD + ++ S S S +S + D
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125
Score = 57.4 bits (137), Expect = 6e-08
Identities = 53/234 (22%), Positives = 87/234 (37%), Gaps = 12/234 (5%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDS-DSDSSDSSSESSSEESDSSSISSHSSASANDVR 718
D + S +SS S+ SS SDSSDS DS S SSESS S+S S S+ ++D
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106
Query: 719 KKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWR 778
S D + ++D + ++ SE +SS S+
Sbjct: 1107 DSSDSSDSSDSSD----SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS-- 1160
Query: 779 DPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTH 838
+SD S+ ++ S +N D D + + S++ +
Sbjct: 1161 -----DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215
Query: 839 RIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRES 892
S++ D S S E + S S + + + + S S+ + ES
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269
Score = 57.0 bits (136), Expect = 8e-08
Identities = 51/242 (21%), Positives = 89/242 (36%), Gaps = 11/242 (4%)
Query: 660 DVEQNKSSPSSSSSASSSSESD---SSDSDSDSSDSSSESSSEESDSSSISSHSSASAND 716
D +S S +SSS D +SD D+ + S +E+ DS S S +++ +N
Sbjct: 469 DESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSN- 527
Query: 717 VRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSN 776
G+G + + DK + +D + ++ + S + S S+
Sbjct: 528 ----GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 777 WRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
D SD S ++ S ++ D D + D K + +S S+++
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSS 643
Query: 837 THRIKD-SENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKN 895
D S+N D S S N S SD + ++ S S S S ++
Sbjct: 644 DSNSSDSSDNSDSSDSSNSS--NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701
Query: 896 QD 897
D
Sbjct: 702 SD 703
Score = 56.6 bits (135), Expect = 1e-07
Identities = 45/155 (29%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDV-R 718
D + S SS S+ SS SDSSDS SDSSDSS S S +S +SS SS SS S++
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195
Query: 719 KKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWR 778
+ S + + ++D + ++ S+ NSS S+
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255
Query: 779 DPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLE 813
+ TSD + S+ + S N+ + D E
Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290
Score = 54.3 bits (129), Expect = 5e-07
Identities = 45/241 (18%), Positives = 95/241 (39%), Gaps = 11/241 (4%)
Query: 666 SSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKT 725
+S +S S + + SDS ++ D SDS+S++++ +S+ + + + ND G GK+
Sbjct: 491 ASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD---NDKSDSGKGKS 547
Query: 726 RSKEVDK--LIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITK 783
S + D + ++D + + ++ + S+ +S SN D
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD---- 603
Query: 784 YTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNS-FSENEKHTHRIKD 842
+SD S+ ++ S ++ + + ++ D K + +S S+N +
Sbjct: 604 -SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662
Query: 843 SENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREK 902
S + D S S + + S S + + + E S +S + D
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 903 S 903
S
Sbjct: 723 S 723
Score = 53.1 bits (126), Expect = 1e-06
Identities = 51/246 (20%), Positives = 99/246 (40%), Gaps = 15/246 (6%)
Query: 664 NKSSPSSSSSASSSSESDSSDSD-----------SDSSDSSSESSSEESDSSSISSHSSA 712
NK S++ S S+S DS D D SD S+ + +++SE ++SS +S
Sbjct: 434 NKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASY 493
Query: 713 SANDVRKKGHGK-TRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQN 771
++++ + G+G ++ E D TN+ +++ + D +
Sbjct: 494 NSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553
Query: 772 SSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFS 831
SS S+ + +SD D S +N S ++ D + ++ D +S S
Sbjct: 554 SSDSS-NSSDSSDSSDSD--SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS 610
Query: 832 ENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRE 891
+ + DS++ K S S + + K S S+ + ++ +S S S +
Sbjct: 611 SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670
Query: 892 SKKNQD 897
S + D
Sbjct: 671 SSDSSD 676
Score = 52.4 bits (124), Expect = 2e-06
Identities = 28/81 (34%), Positives = 40/81 (49%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRK 719
D + S SS S+ S+ SDSSDS S S+S SS+ SDSS +S S+ ++ K
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Query: 720 KGHGKTRSKEVDKLIRNQQTN 740
G+G + D +N
Sbjct: 1275 SGNGNNNGSDSDSDSEGSDSN 1295
Score = 51.6 bits (122), Expect = 3e-06
Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 14/139 (10%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRK 719
D + +S SS S+ SS SDSSDS SDSSDSS S S +S SS SS SS S++
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSD---- 1227
Query: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRD 779
S D + +N + + K + N++GS+
Sbjct: 1228 SSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSD--- 1284
Query: 780 PITKYTSDKDVPSERNNYS 798
SD D +N+S
Sbjct: 1285 ------SDSDSEGSDSNHS 1297
Score = 50.4 bits (119), Expect = 7e-06
Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 6/144 (4%)
Query: 662 EQNKSSPSSSSSAS--SSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRK 719
+ + SS SS SS S SS+ SDSSDS S S S SS+ SDSS S S +S +
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRD 779
+ S + ++ + ++D + ++ S D S N +
Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280
Query: 780 PITKYTSDKDVPSERNNYSRVAND 803
SD D SE ++ + +D
Sbjct: 1281 ----NGSDSDSDSEGSDSNHSTSD 1300
Score = 43.9 bits (102), Expect = 7e-04
Identities = 27/68 (39%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 657 QKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESS--------SEESDSSSISS 708
+ D + S SS+S+ SS SDSSDS SDS+D S S +SDS S S
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292
Query: 709 HSSASAND 716
S+ S +D
Sbjct: 1293 DSNHSTSD 1300
Score = 32.3 bits (72), Expect = 2.1
Identities = 14/38 (36%), Positives = 22/38 (57%)
Query: 662 EQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSE 699
+ N S S S S + ++ SDSDS+ SDS+ +S +
Sbjct: 1264 DSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 31.6 bits (70), Expect = 3.5
Identities = 55/276 (19%), Positives = 105/276 (38%), Gaps = 33/276 (11%)
Query: 650 TPKVIVAQKPDVEQNKSSPSSSSSA---SSSSESDSSDSDSDSSDSSSESSSEESDSSSI 706
TP+ I +++ ++ + +P + A +S + +D D + S + EE+ +
Sbjct: 214 TPQ-INSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKD 272
Query: 707 SSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQ--KERRQEHGHQETRTERERRS 764
SS++S K G+ KE D Q +D K+ +E H E ++ +S
Sbjct: 273 SSNNS-------KGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKS 325
Query: 765 EKH-----------RDQNSSGSNWRDP------ITKYTSDKDVPSERNNYSRVANDRDQE 807
E++ R +++ N R+ ITK + V ++ +
Sbjct: 326 EENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGN 385
Query: 808 MHIDLE-NKHGDPKKKRGERRNSFSE-NEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSR 865
+I E K + K+ +G+ + N K + + E +K +K + ++GS
Sbjct: 386 RNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNK-VGHSNTGSD 444
Query: 866 SDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRRE 901
S+ D Y + S ES N D E
Sbjct: 445 SNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSE 480
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 77.4 bits (189), Expect = 6e-14
Identities = 73/263 (27%), Positives = 113/263 (42%), Gaps = 23/263 (8%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESD---SSSISSHSSA 712
+Q + KS S + S + S + + S S S SSS+E D SSS S
Sbjct: 330 SQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR 389
Query: 713 SANDVRKKGHGKTRSKEVDKLI-RNQQTNDRKQKERRQEHGHQETRT-ERERRSEKHRDQ 770
S + K +RS+ +K R++ + K ++R + + R R R K RD+
Sbjct: 390 SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDR 449
Query: 771 NSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKH---GDPKKKRGERR 827
+ S S +K R+ A DR + E H G P K+R RR
Sbjct: 450 SRSRS----------PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRR 499
Query: 828 NSFSENEKHTHRIKDSENFR--RKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRY 885
+ E+ + + S R R+ RS SKE R+ S S + E ++ ++ R R
Sbjct: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE---RDRSQSRSPSEERE 556
Query: 886 SEQSRESKKNQDRRREKSPAKQK 908
QSR K +DRRR +SP+K++
Sbjct: 557 HRQSRSPSKERDRRRWRSPSKER 579
Score = 68.2 bits (165), Expect = 3e-11
Identities = 70/281 (24%), Positives = 110/281 (39%), Gaps = 24/281 (8%)
Query: 642 ELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDS-DSSDSSSESSSEE 700
E+ +K+ + +P SP S S S S S + S + S + +
Sbjct: 261 EMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRK 320
Query: 701 SDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTER 760
S + HS + ++ KG + +S+ + R+ + KER H ++
Sbjct: 321 GILSQMGRHSQSRSHS---KGKSQNQSR-TPRRGRSHNWSRNPSKERSHSHSRSSSKERD 376
Query: 761 ER-----RSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENK 815
R R E R Q+ S + RD + +K R+ A DR + NK
Sbjct: 377 HRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS---PNK 433
Query: 816 HGDPKKKRG-----ERRNSFSENEKHTHRIKDSENFRR---KDRSKSKEMNRKHSGSRSD 867
D + R +R S S N+ H S N R + RS SKE + GS S
Sbjct: 434 ARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSK 493
Query: 868 EDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
E ++ E+ R QSR S K +D RR +SP+K++
Sbjct: 494 ERDHRRSRSPSKERQCR---QSRSSSKERDHRRSRSPSKER 531
Score = 61.2 bits (147), Expect = 4e-09
Identities = 68/283 (24%), Positives = 117/283 (41%), Gaps = 36/283 (12%)
Query: 650 TPKVIVAQKPD---VEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSI 706
TP Q P ++ +PS SSS S + S S +E SS +
Sbjct: 213 TPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSR------V 266
Query: 707 SSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKER-RQEHGHQETRTER----- 760
S++ AS R + H ++RS + ++T+ R + ++ H +RT +
Sbjct: 267 KSYNQASTRS-RPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQ 325
Query: 761 ------ERRSEKHRDQNSS-------GSNW-RDPITKYTSDKDVPSERNNYSRVANDRDQ 806
R K + QN S NW R+P + + S + R ++ +
Sbjct: 326 MGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK 385
Query: 807 EMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS 866
E ++ G P K+R R S S N K R + ++ +DRS+S+ N+ SRS
Sbjct: 386 ESG---RSQSGSPNKQRDHSR-SRSPN-KARDRSRSRSPYKARDRSRSRSPNKARDCSRS 440
Query: 867 DED-RYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ ++ + R +R +SR K +DR R +SP+K++
Sbjct: 441 RSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKER 483
Score = 60.8 bits (146), Expect = 5e-09
Identities = 68/274 (24%), Positives = 110/274 (40%), Gaps = 25/274 (9%)
Query: 656 AQKPDVEQNKSSPSSSSS-----ASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHS 710
++ P E++ S SSS SSS +S S S S + + S S + +
Sbjct: 356 SRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSR 415
Query: 711 SASANDVRKKGHGKTRSKEVD---------KLIRNQQTNDRKQKERRQEHGHQETRTE-R 760
S S R + ++ +K D R++ + K ++ + + R R
Sbjct: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
Query: 761 ERRSEKHRDQNSSGS--NWRDPITKYTSDKDVPSERNNYSRVAND--RDQEMHIDLENKH 816
R K RD + GS RD + K+ ++ S D R + + + +
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535
Query: 817 GDPKKKRGERRNSFSENEKHTHRIKDS---ENFRRKDRSKSKEMNRKHSGSRSDEDRYQN 873
K +R S S +E+ HR S E RR+ RS SKE R+ S S S+E +
Sbjct: 536 SRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEE--RDH 593
Query: 874 GAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQ 907
R K S YS + R S K + R ++P+K+
Sbjct: 594 SRSRSPNKQSGYS-RPRASSKEKAHSRSRTPSKE 626
Score = 58.5 bits (140), Expect = 3e-08
Identities = 58/255 (22%), Positives = 100/255 (39%), Gaps = 17/255 (6%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSS-----ESSSEESDSSSISSHS 710
++ P+ +++S S A S S S + D S S S + S S + +
Sbjct: 404 SRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSR 463
Query: 711 SASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKE-RRQEHGHQETRTERERRSEKHRD 769
S S N R + ++ SKE D +Q + K+++ RR +E + + R S K RD
Sbjct: 464 SRSPNKARDRSRSRSPSKERD---HSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD 520
Query: 770 QNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNS 829
S S ++ + + + +R+ + +R+ + P K+R RR
Sbjct: 521 HRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHR-------QSRSPSKERDRRRWR 573
Query: 830 FSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQS 889
E+ + + S R RS+S +S R+ + R K +S QS
Sbjct: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHS-QS 632
Query: 890 RESKKNQDRRREKSP 904
R S K D + P
Sbjct: 633 RTSSKESDPSQSTVP 647
Score = 43.9 bits (102), Expect = 7e-04
Identities = 47/225 (20%), Positives = 90/225 (40%), Gaps = 29/225 (12%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHS----- 710
++ P+ +++S S S S+ S + D S S S + S SS
Sbjct: 464 SRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRR 523
Query: 711 SASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRT------ERERRS 764
S S + R++ ++ +KE D+ + +R+ ++ R ++ R ERERR
Sbjct: 524 SRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ 583
Query: 765 EKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKK-- 822
+ + S R P++++ YSR ++ H ++ P K+
Sbjct: 584 SRSSSEERDHSRSRS-----------PNKQSGYSRPRASSKEKAH----SRSRTPSKEGN 628
Query: 823 RGERRNSFSENEKHTHRIKDSENFRRK-DRSKSKEMNRKHSGSRS 866
+ R S E++ + S +++R R+ S NR S + S
Sbjct: 629 HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673
Score = 37.7 bits (86), Expect = 0.049
Identities = 61/283 (21%), Positives = 113/283 (39%), Gaps = 41/283 (14%)
Query: 654 IVAQKPDVEQNK-SSPSSS-SSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSS 711
+V KP +N SPSSS S+ S+S++ S+ S S S++ + S+ + +
Sbjct: 44 LVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKA 103
Query: 712 ASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKE-----RRQEHGHQETRTERERRSEK 766
+ A+DVR T S+ R +++ R R + HG + R R+
Sbjct: 104 SKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRV-RTPT 162
Query: 767 HRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVAN--------DRDQEMHI-----DLE 813
+ + S G ++ P T D S+ N S+ + R E+ + +
Sbjct: 163 SQQKGSRGKSYGRPRTSNRERSD--SQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQ 220
Query: 814 NKHGDPKKKRGERRNSFS-------------ENEKHTHRIKDSENFRRKDRSKSKEMNRK 860
G P K++ + + S EK + S + +++ ++ +
Sbjct: 221 TPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQS 280
Query: 861 HSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKS 903
HS SRS R ++G+++R R S K+N R R ++
Sbjct: 281 HSQSRSPR-RSRSGSQKRTHSRVR----SHSWKRNHSRARSRT 318
Score = 37.4 bits (85), Expect = 0.064
Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 8/121 (6%)
Query: 11 SSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYD-SSMESR 69
S H R + R SS + + +S D+SRS + R RS S ++R
Sbjct: 364 SHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKAR 423
Query: 70 NRDREKRRERERDTDRKRS-------RKSPSPGRRNPETSVTQSSSAQDEPATKKKKDEL 122
+R R + + RD R RS +S SP + + + A+D ++ E
Sbjct: 424 DRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKER 483
Query: 123 D 123
D
Sbjct: 484 D 484
Score = 37.0 bits (84), Expect = 0.083
Identities = 34/116 (29%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
Query: 10 PSSGHDRRENLNS-----YQRNSSP-EDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYD 63
PS R++ +S ++R+ SP ++R Q RSP SRS E +S
Sbjct: 503 PSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRS 562
Query: 64 SSME-SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
S E R R R +ERER R S + R+P QS ++ ++K+K
Sbjct: 563 PSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN---KQSGYSRPRASSKEK 615
Score = 36.2 bits (82), Expect = 0.14
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 15/125 (12%)
Query: 10 PSSGHDRRENLN------SYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYD 63
PS D R + + Q SS ++R + RSP SRS + R +S
Sbjct: 491 PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRS 550
Query: 64 SSME---------SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPA 114
S E S+ RDR + R ++ +R++SR S + S + S A
Sbjct: 551 PSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRA 610
Query: 115 TKKKK 119
+ K+K
Sbjct: 611 SSKEK 615
Score = 34.7 bits (78), Expect = 0.41
Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 12/111 (10%)
Query: 10 PSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESR 69
PS +RR Q SS E+R + RSP + + R+ + RS S E
Sbjct: 575 PSKERERR------QSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEG- 627
Query: 70 NRDREKRRERERDTDRKRSRKSPSPGRRNPETSV-----TQSSSAQDEPAT 115
N + + +E D + +SP R TS T S ++ P+T
Sbjct: 628 NHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPST 678
Score = 33.9 bits (76), Expect = 0.71
Identities = 28/112 (25%), Positives = 44/112 (39%), Gaps = 6/112 (5%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSME-SRNRDREKRRERERD 82
Q S ++R + RSP SRS + RS S E R + R +ER+R
Sbjct: 487 QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS 546
Query: 83 TDRKRS-----RKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRT 129
R S R+S SP + S ++ ++ +E D +R+
Sbjct: 547 QSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRS 598
Score = 32.7 bits (73), Expect = 1.6
Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 9/89 (10%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
RR +++ RN S E + S ++RD+ S E R + +R R
Sbjct: 348 RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSP 407
Query: 76 RRERERD--------TDRKRSRKSPSPGR 96
+ R+R DR RSR SP+ R
Sbjct: 408 NKARDRSRSRSPYKARDRSRSR-SPNKAR 435
Score = 32.0 bits (71), Expect = 2.7
Identities = 37/134 (27%), Positives = 53/134 (39%), Gaps = 15/134 (11%)
Query: 10 PSSGHDRRENLNSY------QRNSSPEDRYEEQERSP-RDRDYFDYSRSDYEHSRRGRSY 62
PS RR++ + Q S E+R Q RSP ++RD + E RR +S
Sbjct: 527 PSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR-QSR 585
Query: 63 DSSME---SRNRDREKR----RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPAT 115
SS E SR+R K+ R R ++ SR N S T S + +T
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
Query: 116 KKKKDELDPLLTRT 129
+ + TRT
Sbjct: 646 VPRSPDWKRSPTRT 659
Score = 31.6 bits (70), Expect = 3.5
Identities = 31/128 (24%), Positives = 48/128 (37%), Gaps = 19/128 (14%)
Query: 12 SGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRS---------- 61
S R+E+ S Q S + R + RSP SRS Y+ R RS
Sbjct: 380 SSSPRKESGRS-QSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS 438
Query: 62 -----YDSSMESRNRDREKRRERERDTDRKRSR---KSPSPGRRNPETSVTQSSSAQDEP 113
Y + SR+R K R+ R ++R +S SP + + + S +D
Sbjct: 439 RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR 498
Query: 114 ATKKKKDE 121
++ E
Sbjct: 499 RSRSPSKE 506
Score = 31.6 bits (70), Expect = 3.5
Identities = 32/138 (23%), Positives = 54/138 (39%), Gaps = 7/138 (5%)
Query: 23 YQRNSSPED-RYEEQERSP-RDRDYFDYSRSDYEHS-RRGRSYDSSMESR-NRDREKRRE 78
+ R+ SP R + RSP ++RD+ E RR RS + R +R K R+
Sbjct: 461 HSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD 520
Query: 79 RERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTGGAYIPPAK 138
R + R+ N E +QS S +E ++ + P R + P+K
Sbjct: 521 HRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEE---REHRQSRSPSKERDRRRWRSPSK 577
Query: 139 LRMMQEQITDKNSLAYQR 156
R ++ + + R
Sbjct: 578 ERERRQSRSSSEERDHSR 595
Score = 30.4 bits (67), Expect = 7.8
Identities = 30/127 (23%), Positives = 51/127 (40%), Gaps = 17/127 (13%)
Query: 10 PSSGHDRRENLNSYQ-----RNSSPEDRYE-EQERSP---RDRDYFDYSRSDYEHSRRGR 60
P+ DR + + Y+ R+ SP + + RSP RDR +HSR
Sbjct: 407 PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRS 466
Query: 61 SYDSSMESRNRDREKRRE--------RERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDE 112
+ SR+R K R+ +ERD R RS R++ +S +
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
Query: 113 PATKKKK 119
P+ ++++
Sbjct: 527 PSKERQR 533
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 73.9 bits (180), Expect = 6e-13
Identities = 48/192 (25%), Positives = 89/192 (46%), Gaps = 8/192 (4%)
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKER-RQEHGHQETRTERERRSEKHRDQNSSGSN 776
R+ GK +E D+ + +R+ + R R H ++ +T+RE+ E+ ++++
Sbjct: 9 RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQR 68
Query: 777 WRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
R+ T+ +++ +R + DR+++ D E K + + R R E +K
Sbjct: 69 ERE--TERETERQRERQRQRERKRQTDRERDKDRDRERKR-ETDRNRERNRKGGRERDKQ 125
Query: 837 THRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRE--SKK 894
T R +D E R + R + +E R+ R + Q AER K R E+ +E KK
Sbjct: 126 TERERDRE--RERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK 183
Query: 895 NQDRRREKSPAK 906
+++RRE K
Sbjct: 184 KEEKRREDKKRK 195
Score = 57.0 bits (136), Expect = 8e-08
Identities = 36/163 (22%), Positives = 76/163 (46%), Gaps = 5/163 (3%)
Query: 741 DRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRV 800
+R+++ +R+ +ET ER+R+ E+ +Q + R D+ E+ +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRER-ENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 801 ANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRK 860
DR ++ + E + +++R +R + + R KD + R+++ +++E NRK
Sbjct: 61 ERDRQRQRERETER---ETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Query: 861 HSGSRSDEDRYQNGAER-RWEKSSRYSEQSRESKKNQDRRREK 902
R + + ER R + R ++ RE K+ DR R++
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR 160
Score = 48.5 bits (114), Expect = 3e-05
Identities = 38/190 (20%), Positives = 84/190 (44%), Gaps = 14/190 (7%)
Query: 683 SDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDR 742
++ + D + E+ H R+K + R KE D+ + ++ +R
Sbjct: 17 TERERDRQRERENQTERENRHRQRDRHRERDRQTDREKE--RERQKERDRQRQRERETER 74
Query: 743 KQKERRQEHGHQETR--TERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRV 800
+ + +R+ +E + T+RER ++ R++ R+ K ++D +ER
Sbjct: 75 ETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERE----- 129
Query: 801 ANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRK 860
DR++E E + +++R +R + E ++ R ++ + R+K+R K ++ +K
Sbjct: 130 -RDRERERQRQRERER---QRQRERKRETDRERQRWAER-EERKKERKKERKKERKEKKK 184
Query: 861 HSGSRSDEDR 870
R D+ R
Sbjct: 185 EEKRREDKKR 194
Score = 44.3 bits (103), Expect = 5e-04
Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 18 ENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRR 77
E QR + + + + RDR+ + + E +R+G R RDRE+ R
Sbjct: 77 ERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERER 136
Query: 78 ERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
+R+R+ +R+R R+ R ET + A+ E K++K E
Sbjct: 137 QRQRERERQRQRE------RKRETDRERQRWAEREERKKERKKE 174
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 9/108 (8%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSP-RDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDR 73
DR + + + DR E+ R R+RD D E R+ R R+R
Sbjct: 93 DRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQ--------RQRERER 144
Query: 74 EKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
+++RER+R+TDR+R R + R+ + + + K+++D+
Sbjct: 145 QRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
Score = 41.6 bits (96), Expect = 0.003
Identities = 25/112 (22%), Positives = 53/112 (47%), Gaps = 3/112 (2%)
Query: 793 ERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRS 852
ER + + ++E E ++ ++ R +R+ E ++ T R K+ E R+K+R
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE--RQKERD 63
Query: 853 KSKEMNRK-HSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKS 903
+ ++ R+ + +R + +R R ++ RE K+ DR RE++
Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
Score = 40.8 bits (94), Expect = 0.006
Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 4/109 (3%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSME-SRNRDRE 74
+RE R E + Q + + R H R R D E R ++R+
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
++R+RER+T+R+ R+ R+ Q+ +D+ +++K E D
Sbjct: 64 RQRQRERETERETERQRE---RQRQRERKRQTDRERDKDRDRERKRETD 109
Score = 39.3 bits (90), Expect = 0.017
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 2/97 (2%)
Query: 7 QIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSM 66
Q + + H +R+ R + E E Q+ R R + + E R +
Sbjct: 30 QTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERK 89
Query: 67 ESRNRDREKRRERE--RDTDRKRSRKSPSPGRRNPET 101
+R+R+K R+RE R+TDR R R R+ +T
Sbjct: 90 RQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQT 126
Score = 37.7 bits (86), Expect = 0.049
Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 34 EEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDR--KRSRKS 91
E Q R+ D + + + R R + E+R+R R++ RER+R TDR +R R+
Sbjct: 2 ERQRERKRETDRGKETERERDRQRE-RENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 92 PSPGRRNPETSVTQSSSAQDEPATKKKK 119
+R E + + Q E ++++
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRER 88
Score = 35.4 bits (80), Expect = 0.24
Identities = 18/88 (20%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 820 KKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRW 879
++KR R +E E+ R ++++ R++R + ++ +R+ ++D ++ + + R
Sbjct: 6 ERKRETDRGKETERERDRQRERENQT-ERENRHRQRDRHRERD-RQTDREKERERQKERD 63
Query: 880 EKSSRYSEQSRESKKNQDRRREKSPAKQ 907
+ R E RE+++ ++R+R++ +Q
Sbjct: 64 RQRQRERETERETERQRERQRQRERKRQ 91
Score = 35.4 bits (80), Expect = 0.24
Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
REN + DR+ E++R DR+ + R +R R ++ E+ R RE++
Sbjct: 27 RENQTERENRHRQRDRHRERDRQT-DREK-ERERQKERDRQRQRERETERETE-RQRERQ 83
Query: 77 R--------ERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
R +RERD DR R RK + RN E + + + + T++++D
Sbjct: 84 RQRERKRQTDRERDKDRDRERKRETD--RNRERN--RKGGRERDKQTERERD 131
Score = 33.9 bits (76), Expect = 0.71
Identities = 21/85 (24%), Positives = 37/85 (43%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
++E QR E E Q R R+ + + + R + +R R+R+
Sbjct: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
Query: 76 RRERERDTDRKRSRKSPSPGRRNPE 100
RER++ T+R+R R+ +R E
Sbjct: 119 GRERDKQTERERDRERERQRQRERE 143
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 73.9 bits (180), Expect = 6e-13
Identities = 55/281 (19%), Positives = 117/281 (41%), Gaps = 36/281 (12%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDS----------DSSDSSSESSSEESDSSSISSHSSAS 713
++ SP + ++D D + + + E+ + H
Sbjct: 33 SQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD 92
Query: 714 ANDVRKKGHGKTRSKEVDKLIRNQQTNDR-KQKERRQEHGHQETR---------TERERR 763
+ R++ K R ++ D+ Q+ +R +QKER +E + R ERER+
Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQ 152
Query: 764 SEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKR 823
+ +++ R T+ K+ E+N R +R +E E++H + ++R
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER 212
Query: 824 GERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS---------------DE 868
R + +E E+ ++ + R+ +R + K+ R+ + R D
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
Query: 869 DRYQNGAERRWE-KSSRYSEQSRESKKNQDRRREKSPAKQK 908
DR Q ER+ + K R +E+ RE+++ ++R+RE+ +++
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
Score = 72.4 bits (176), Expect = 2e-12
Identities = 54/265 (20%), Positives = 114/265 (43%), Gaps = 19/265 (7%)
Query: 644 REHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDS 703
RE KN + ++ ++NK+ S ++++++ ++ E
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK---RQTDRERDRQ 235
Query: 704 SSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKER-RQEHGHQETRTERER 762
A R R KE ++ + DR+QKER RQ ++ RTER+R
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
Query: 763 RSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKK 822
+E+ R++ +++ ERN +R++E E + D +K+
Sbjct: 296 ETERKRERQR--------------ERERERERNRKRERERERERERERQRETER-DREKE 340
Query: 823 RGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKS 882
R +R +E ++ +R E R+ +R + +E R +R E+R ++ R ++
Sbjct: 341 RERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER 400
Query: 883 SRYSEQSRESKKNQDRRREKSPAKQ 907
R +E+ R+ ++ +++RE+ ++
Sbjct: 401 ERQTEKDRDGQRETEKQREREKDRE 425
Score = 70.9 bits (172), Expect = 5e-12
Identities = 49/258 (18%), Positives = 112/258 (43%), Gaps = 20/258 (7%)
Query: 662 EQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKG 721
E+ + + + + + + + + E ++ + HS ++G
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS--------ERG 209
Query: 722 HGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRD-- 779
+ R +E + ++ DR++ +R+ +E + ERER SE+ +++ RD
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 780 -PITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTH 838
+ +++ ++R R DR+ E + + + + +++R +R E E+
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER-ERERERNRKRERERERERERE 328
Query: 839 RIKDSENFRRKDRSKSK----EMNRKHSGSRSDEDRYQNGAERRWEKS----SRYSEQSR 890
R +++E R K+R + + EM+R+ + E R Q ER E+ S + R
Sbjct: 329 RQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER 388
Query: 891 ESKKNQDRRREKSPAKQK 908
E +++DR++E+ +K
Sbjct: 389 ERDRDRDRQKERERQTEK 406
Score = 69.3 bits (168), Expect = 2e-11
Identities = 51/247 (20%), Positives = 96/247 (38%), Gaps = 24/247 (9%)
Query: 679 ESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQ 738
E D + E +E + R++ K R ++ D+ R +Q
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE-RQRQ 170
Query: 739 TNDRKQKERRQEHGHQETRT----------------------ERERRSEKHRDQNSSGSN 776
T +QKER +E QE R ERER +E ++
Sbjct: 171 TERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230
Query: 777 WRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
RD K +++ +ER S +RD+E + + ++++ R + + ++
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 837 THRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQ 896
T R +++E R + R + +E R R E + +R E+ R E+ R+ K+
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETER-DREKERERKRKRQT 349
Query: 897 DRRREKS 903
+ RE++
Sbjct: 350 EMDRERN 356
Score = 69.3 bits (168), Expect = 2e-11
Identities = 44/247 (17%), Positives = 101/247 (40%), Gaps = 11/247 (4%)
Query: 657 QKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAND 716
++ D E+++ + + +S+ +++ + D +
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTD- 284
Query: 717 VRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSN 776
RK+ R +E ++ Q+ +R+++ R+ +E ERER+ E RD+
Sbjct: 285 -RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERER 343
Query: 777 WRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
R T+ +++ + R + +R++E D ++ +++R R+ E E+
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
Query: 837 THRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQ 896
T + +D + K R + K+ + R E Q G ER ++ R++ +
Sbjct: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRER---------DRERQTDRQA 454
Query: 897 DRRREKS 903
R+R++S
Sbjct: 455 GRQRKRS 461
Score = 66.2 bits (160), Expect = 1e-10
Identities = 49/282 (17%), Positives = 116/282 (41%), Gaps = 16/282 (5%)
Query: 641 DELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEE 700
D +E + T + Q+ + E+N+ + +D + +E
Sbjct: 100 DREKERERQTDRERDRQR-EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158
Query: 701 SDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQ------ 754
+ + + + R+K + ++++ + Q+ + K ++R E G +
Sbjct: 159 RERQTDRERQRQTERN-RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 755 -ETRTERERRSEKHRDQNSSGSNWRDPITKY--TSDKDVPSERNNYSRVANDRDQEMHID 811
ET TER+R++++ RD+ R+ + S+++ ++ DRD++
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
Query: 812 LENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRY 871
+ D K++R R+ +E ++ R ++ E R + R + +E R+ R E
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDR 337
Query: 872 QNGAERRWEKSS-----RYSEQSRESKKNQDRRREKSPAKQK 908
+ ER+ ++ + R + RE ++ +R RE+ + +
Sbjct: 338 EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDR 379
Score = 48.1 bits (113), Expect = 4e-05
Identities = 30/106 (28%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 17 RENLNSYQRNSSPEDRYEE--QERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
RE +RN E E+ QER R+R ++++ HS RGR + R R+ E
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE-----RERETE 219
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
ER+R TDR+R R+ + R + ++S + E +++++
Sbjct: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/106 (25%), Positives = 47/106 (44%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
DRR+ Q + + R E + R R+ + E +R+ R R RE
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
R+RE++ +RKR R++ RN +T A+ E ++++D
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERD 378
Score = 46.6 bits (109), Expect = 1e-04
Identities = 25/107 (23%), Positives = 50/107 (46%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
R+ +R+ E + E Q R+R+ + E R + R ++RE++
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 77 RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
R+R+ + DR+R+R++ GRR E + + A ++++ E D
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Score = 44.3 bits (103), Expect = 5e-04
Identities = 36/131 (27%), Positives = 51/131 (38%), Gaps = 4/131 (3%)
Query: 12 SGHDRRENLNSYQRNSSPE-DRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES-- 68
S +R E R+ E +R E++R + R S RGR E
Sbjct: 381 SAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK 440
Query: 69 -RNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLT 127
R RDRE++ +R+ RKRS +P R + V QS + + K DP
Sbjct: 441 GRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAA 500
Query: 128 RTGGAYIPPAK 138
T + PAK
Sbjct: 501 STRFPWGRPAK 511
Score = 43.5 bits (101), Expect = 9e-04
Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 6/120 (5%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
RE +R S E +++ RDRD D R E R+ R+R+ E++
Sbjct: 242 REKQAERERASERETERDKERERERDRDR-DRDRRQKERERQTDRKRQRRTERDRETERK 300
Query: 77 RERERDTDRKRSRKSPSPGRRNPETS-----VTQSSSAQDEPATKKKKDELDPLLTRTGG 131
RER+R+ +R+R R R E T+ ++ +K++ E+D R G
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 16/119 (13%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERS-PRDRD---------YFDYSRSDYEHSRRGRSYDS 64
+RRE ++ + EDR+ E+ R R+R+ D R + R R +
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
Query: 65 SME---SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
E R +R+K RERERD DR R R+ R +T + + + T++K++
Sbjct: 247 ERERASERETERDKERERERDRDRDRDRRQK---ERERQTDRKRQRRTERDRETERKRE 302
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 5/119 (4%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQE--RSPRDRDYFDYSRSDYEHSRRGRSYDSSM 66
K + G DR N +R E R E+E R R D R H R R +
Sbjct: 47 KDADGDDRERNRQK-ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105
Query: 67 ESR-NRDREKRRERERDTDRKRSRKSPSPGRRNPETSVT-QSSSAQDEPATKKKKDELD 123
E + +R+R+++RE+ER+ ++R R++ G R + Q + A K+++ + D
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTD 164
Score = 42.0 bits (97), Expect = 0.003
Identities = 23/108 (21%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
+R+ + + + +R + ER+ + + +R + R R ++ E R+ +R
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPE--TSVTQSSSAQDEPATKKKKD 120
+ RERER+T+ + RK + R+ + T + A+ E A++++ +
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/116 (24%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 14 HDRRENLNSYQRNSSPE-----DRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSS-ME 67
H +R+ QR+ E DR +++R + R RGR +
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 68 SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
R R R+ +ERER TDR+R R++ ++ E + + E +K+ D
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Score = 40.0 bits (92), Expect = 0.010
Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
RE QR + DR +E+ER + + D R + + R GR R R+R+++
Sbjct: 323 RERERERQRETE-RDREKERERKRKRQTEMDRER-NRQTGREGRRQAERERERERERDRQ 380
Query: 77 RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
RER+ +R+R R R +T + + E +++KD
Sbjct: 381 SARERE-ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423
Score = 39.7 bits (91), Expect = 0.013
Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSME-SRNRDREK 75
R+ +RN E E + R RD R R R D+ E R DRE+
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRD-----RQTDGQRERERQRDAEKERERQTDRER 167
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
+R+ ER+ ++R R+ RR E + + +D + + ++ E
Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Score = 38.9 bits (89), Expect = 0.022
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
RR L +++ +DR +++ R + + + R R R+R RE+
Sbjct: 38 RRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRER 97
Query: 76 RR----ERERDTDRKRSRKSPSPGRRNPE 100
+R ERER TDR+R R+ R E
Sbjct: 98 QRDREKERERQTDRERDRQREKERNRQKE 126
Score = 38.5 bits (88), Expect = 0.029
Identities = 27/105 (25%), Positives = 43/105 (40%), Gaps = 1/105 (0%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
+RE +RN E E + R R+ + E R+ ++ +R RE
Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
RR+ ER+ +R+R R S R E + Q E + +KD
Sbjct: 364 RRQAERERERERERDRQS-AREREERERDRDRDRQKERERQTEKD 407
Score = 36.6 bits (83), Expect = 0.11
Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 9/92 (9%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K H R +R + E + Q RDR + + R S +
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
Query: 69 RNRDREKRR---------ERERDTDRKRSRKS 91
+ R+RE+ R ERER TDRKR R++
Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Score = 35.4 bits (80), Expect = 0.24
Identities = 22/105 (20%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSR-RGRSYDSSMESRNRDREK 75
R+ +R+ + E ++++ R+R + D E R R R D + R+R+
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQT 283
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
R+R+R T+R R + +R E ++ + E +++++
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328
Score = 35.4 bits (80), Expect = 0.24
Identities = 19/86 (22%), Positives = 38/86 (44%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
DR + ++ + DR ++ R + R R + + R+RDR+
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPE 100
+++ERER T++ R + + +R E
Sbjct: 396 RQKERERQTEKDRDGQRETEKQRERE 421
Score = 35.0 bits (79), Expect = 0.32
Identities = 22/108 (20%), Positives = 43/108 (39%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
+RE +R + E + R+R+ + D E R + + R R+R+
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
RE R +R+R R+ + E + +D ++++ E D
Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Score = 34.3 bits (77), Expect = 0.54
Identities = 26/110 (23%), Positives = 47/110 (42%), Gaps = 9/110 (8%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
DR+ + DR+ E++R DR+ ++D E R+ + + R+RE
Sbjct: 76 DRKRERRREKDRHRKRDRHRERQR---DREKERERQTDRERDRQREKERN--RQKERERE 130
Query: 75 KRRE----RERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
RE R+R TD +R R+ + E + Q E +K+++
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERE 180
Score = 34.3 bits (77), Expect = 0.54
Identities = 23/109 (21%), Positives = 49/109 (44%), Gaps = 7/109 (6%)
Query: 13 GHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRD 72
G DR+ + +R + E + ++ R+R R + ++ R + + + R R+
Sbjct: 138 GRDRQTD-GQRERERQRDAEKERERQTDRERQ-----RQTERNRQKEREREKNRQER-RE 190
Query: 73 REKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
RE++RE+E T+ + S + R + T+ D +++K E
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTE 239
Score = 33.1 bits (74), Expect = 1.2
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSME------- 67
DR N + + +R E+ER RDR S + E R R D E
Sbjct: 352 DRERNRQTGREGRRQAERERERERE-RDRQ----SAREREERERDRDRDRQKERERQTEK 406
Query: 68 SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQ-DEPATKKKK 119
R+ RE ++RER+ DR+ R R + + Q D A +++K
Sbjct: 407 DRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 31.2 bits (69), Expect = 4.6
Identities = 20/111 (18%), Positives = 45/111 (40%), Gaps = 3/111 (2%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K + RE + + + + Q R RD + R+ ++ + +
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 69 RNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
R R++ ++ RER+ R++ K+ R+ E + + E T++K+
Sbjct: 179 REREKNRQERRERERQREKENKTED---RHSERGRERERERETETETERKR 226
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 73.9 bits (180), Expect = 6e-13
Identities = 89/354 (25%), Positives = 141/354 (39%), Gaps = 105/354 (29%)
Query: 652 KVIVAQKPDVEQNKSSPSSSSSASSSSESD-SSDSDSDSSDSSSESSSEESD-------- 702
++I K E+ K SSSSS+SSSS+SD SSDS S S S SES++EE
Sbjct: 176 ELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR 235
Query: 703 --------------SSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQ----------Q 738
S S+ S + A ++ + R +E+ + N+
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKAD 295
Query: 739 TNDRKQKERRQE----------------------------HGHQETRT-------ERERR 763
+RK +ER +E G + RT +R RR
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRR 355
Query: 764 SE-----------KHRDQNSSGSNW---------------RDPITKYTSDKDVPSERNNY 797
SE R + SSG W R P+ ++ + RN
Sbjct: 356 SETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVR--VKERKITDHRNVS 413
Query: 798 SRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENE---KHTHRIKDSENFRRKDRSKS 854
++E + H K+R RRNS +++ K R K + K++SKS
Sbjct: 414 ESPNRKNEKEKKV---KDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKS 470
Query: 855 KEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESK-KNQDRRREKSPAKQ 907
KE + KH +R++E R ++ ++ R ++ + E+ +SK K+Q+R R K +KQ
Sbjct: 471 KERDSKH--NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQ 522
Score = 70.1 bits (170), Expect = 9e-12
Identities = 63/266 (23%), Positives = 115/266 (43%), Gaps = 31/266 (11%)
Query: 660 DVEQNKSSP-----SSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASA 714
++++N+ SP + + SES + ++ + +S+S+E D S
Sbjct: 390 EIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYK 449
Query: 715 NDVRKKGHGKTRSKEVDKL------IRNQQTNDRKQKERRQEHGHQETRTERERRSEKHR 768
N V+K+ K+RSK +K ++ + +++ + R + H+ + + ++ K +
Sbjct: 450 NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509
Query: 769 DQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRN 828
DQ S S + + S++ S+ R A R +E I + KH + R ER
Sbjct: 510 DQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDIT-KGKHSYNSRTR-ERSR 567
Query: 829 SFSENEKHTHRIKDSENFRRKDRSKSKEMN-------RKHSGSRSDEDRYQNGA-----E 876
S + + R D +DRS+SKE + R+ SRS E R G
Sbjct: 568 SRDRSRRVRSRTHD------RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDR 621
Query: 877 RRWEKSSRYSEQSRESKKNQDRRREK 902
RR + SR SE+ +N+D+ R +
Sbjct: 622 RRRRRDSRSSEREESQSRNKDKYRNQ 647
Score = 60.5 bits (145), Expect = 7e-09
Identities = 61/278 (21%), Positives = 113/278 (40%), Gaps = 37/278 (13%)
Query: 642 ELREHLKNTPKVIV---AQKPDVEQNK-------SSPSSSSSASSSSESDSSDSDSDSSD 691
++++H N+ + + ++K D +NK S S S S S E DS + ++
Sbjct: 425 KVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKR 484
Query: 692 SSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEH 751
S S + ++ S S +++ K +SK+++ + K+K+RR +
Sbjct: 485 MRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQS 544
Query: 752 GHQETRTERERRSEKHRDQNSSGSNWRDP-ITKYTSDKDVPSERNNYSRVANDRDQEMHI 810
+E + + S R + S S R + T D+D R +E H
Sbjct: 545 RSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRD------------RSRSKEYHR 592
Query: 811 DLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNR-------KHSG 863
E ++ ++RG R+ R KD RR RS +E ++ ++
Sbjct: 593 YREQEY----RRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQE 648
Query: 864 SRSDEDRYQNGAERRWEKSSR---YSEQSRESKKNQDR 898
S+S + + +E+R SR S SRE K ++D+
Sbjct: 649 SKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQ 686
Score = 58.5 bits (140), Expect = 3e-08
Identities = 57/267 (21%), Positives = 108/267 (40%), Gaps = 22/267 (8%)
Query: 645 EHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSS 704
E++K K ++ D E+++S S S S+E D S S D ++S S E D +
Sbjct: 495 ENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE--KDRRAQSRSRECDIT 552
Query: 705 SISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRS 764
HS S R++ + RS+ V +T+DR + ++ H ++E R RS
Sbjct: 553 K-GKHSYNSRT--RERSRSRDRSRRV-----RSRTHDRDRSRSKEYHRYREQEYRRRGRS 604
Query: 765 EKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRG 824
+ G + + D R++ + R+++ + + E+K K+
Sbjct: 605 RSRERRTPPGRSRSKDRRRRRRDS-----RSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 825 ERRNSFSENEKHTHRIKDSENFRRKDRS-------KSKEMNRKHSGSRSDEDRYQNGAER 877
+ +S++ H E +D+S S++ K S ++ ED +
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVE 719
Query: 878 RWEKSSRYSEQSRESKKNQDRRREKSP 904
+ + S+ E +KN+ E SP
Sbjct: 720 KENQKSKGQENDHVHEKNKKFDHESSP 746
Score = 53.1 bits (126), Expect = 1e-06
Identities = 55/249 (22%), Positives = 97/249 (38%), Gaps = 25/249 (10%)
Query: 641 DELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEE 700
D+ R K K + ++ + + +KS + S S E D + + + E S
Sbjct: 510 DQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSR 569
Query: 701 SDSSSISSHSSASANDVRKKGH----------GKTRSKEVDKLIRNQQTNDRKQKERRQE 750
S + S + K+ H G++RS+E ++ DR++ RR++
Sbjct: 570 DRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR--RRRD 627
Query: 751 HGHQETRTERERRSEKHRDQNSSGS----NWRDPITKYTSDKDVPSERNNYSRVANDRDQ 806
E + R +K+R+Q S S N Y+ +D S N+ + A DRDQ
Sbjct: 628 SRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKA-DRDQ 686
Query: 807 EMHIDLENKHGDPKKKRGERRNSFSEN-----EKHTHRIKDSENFRRKDRSKSKEMNRKH 861
++ D + K +N E EK + K EN +++K +
Sbjct: 687 SPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFD---HE 743
Query: 862 SGSRSDEDR 870
S +DED+
Sbjct: 744 SSPGTDEDK 752
Score = 50.1 bits (118), Expect = 1e-05
Identities = 67/334 (20%), Positives = 114/334 (34%), Gaps = 85/334 (25%)
Query: 652 KVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSS 711
K A KP E S S + + S SS SSS S S+ S S SS SS
Sbjct: 158 KTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSS 217
Query: 712 ASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQ----------------- 754
S + +K K R K+ K R + +K+K+ ++ +
Sbjct: 218 DSESATEEK--SKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPE 275
Query: 755 -------------------ETRTERERRSEKHRDQNSSGS-------------------- 775
+ + + R E+ R+ N S
Sbjct: 276 EIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKG 335
Query: 776 ----NWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENK--HGDPKKKRGERRNS 829
+R P + D+ SE + R R Q M + + GD + N
Sbjct: 336 RGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSE-----LNE 390
Query: 830 FSENEKHTHRIKD---------SENFRRKDRSKSKEMNRKHSGSRSD-------EDRYQN 873
EN++ R+K+ SE+ RK+ + K + K + D +D+Y+N
Sbjct: 391 IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKN 450
Query: 874 GAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQ 907
++R + SR + + K +D + ++ K+
Sbjct: 451 KVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKR 484
Score = 49.7 bits (117), Expect = 1e-05
Identities = 41/193 (21%), Positives = 88/193 (45%), Gaps = 11/193 (5%)
Query: 724 KTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITK 783
K E++++ NQ++ R ++ + +H + R+ EK + S S RD +
Sbjct: 382 KGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD--IR 439
Query: 784 YTSDKD------VPSERNNYSRV-ANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
S+KD V + SR + ++ + D ++ + K+ R + EN K
Sbjct: 440 RNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKE 499
Query: 837 THRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGA-ERRWEKSSRYSEQSRESKKN 895
+ DS+ + ++RS+SKE +++ ++ D ++ +RR + SR + ++
Sbjct: 500 KEKQSDSKG-KDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSY 558
Query: 896 QDRRREKSPAKQK 908
R RE+S ++ +
Sbjct: 559 NSRTRERSRSRDR 571
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 7/125 (5%)
Query: 2 KSSVAQIKPSSGHDRR---ENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRR 58
KS + +IK + R + ++ S +R E+E+ +D S S RR
Sbjct: 385 KSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHK----SNSKERDIRR 440
Query: 59 GRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
D +++ + R K + R + ++ +S++ S RN E + S +D K+K
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEK 500
Query: 119 KDELD 123
+ + D
Sbjct: 501 EKQSD 505
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 1/107 (0%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYF-DYSRSDYEHSRRGRSYDSSMESRNRDR 73
D + +SY + R ++ R R R + D SRS H R + Y SR+R+R
Sbjct: 550 DITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRER 609
Query: 74 EKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
R R DR+R R+ R S + E + +K+
Sbjct: 610 RTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKE 656
Score = 39.7 bits (91), Expect = 0.013
Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 8/118 (6%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRY----EEQERSPRDRDYFDYSRSDYEHSRRGRSYDS 64
K H +RNS +D+Y +++ +S + S+S S+ R+ +
Sbjct: 424 KKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEK 483
Query: 65 SMESRN--RDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
M SR+ RD E +E+E+ +D K K R ++ +S S + + + K+KD
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSDSK--GKDQERSRSKEKSKQLESKSNEHDHSKSKEKD 539
Score = 38.9 bits (89), Expect = 0.022
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDS-SME 67
K S RE S R+ R +++RS R ++Y Y +Y R RS + +
Sbjct: 555 KHSYNSRTRERSRSRDRSRRVRSRTHDRDRS-RSKEYHRYREQEYRRRGRSRSRERRTPP 613
Query: 68 SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
R+R +++RR R RD+ +S S + ++SS ++ ++K+
Sbjct: 614 GRSRSKDRRR-RRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKR 663
Score = 37.4 bits (85), Expect = 0.064
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 10/110 (9%)
Query: 17 RENLNSYQRNSSPE-DRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRD--- 72
R + R+ S E RY EQE R R SRS + GRS R RD
Sbjct: 576 RSRTHDRDRSRSKEYHRYREQEYRRRGR-----SRSRERRTPPGRSRSKDRRRRRRDSRS 630
Query: 73 REKRRERERDTDRKRSRKSPSPGRR-NPETSVTQSSSAQDEPATKKKKDE 121
E+ + R+ D+ R+++S S R+ N E+ S ++D ++ +++
Sbjct: 631 SEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREK 680
Score = 32.0 bits (71), Expect = 2.7
Identities = 21/88 (23%), Positives = 36/88 (40%)
Query: 12 SGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNR 71
S + ++ S +++ + R E + + Y +R R R S R+R
Sbjct: 525 SKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDR 584
Query: 72 DREKRRERERDTDRKRSRKSPSPGRRNP 99
R K R R+ + +R +S S RR P
Sbjct: 585 SRSKEYHRYREQEYRRRGRSRSRERRTP 612
Score = 30.8 bits (68), Expect = 6.0
Identities = 22/110 (20%), Positives = 52/110 (47%), Gaps = 13/110 (11%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
++E ++ +SS + + S + D SD E + +S + R R+
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSD--SSDSESATEEKSKKRKKKHRKNSRKH 241
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPL 125
++E+++ RK+S+KS S S +++ + + +P + + +E+ P+
Sbjct: 242 KKEKKK---RKKSKKSAS--------SESEAENLEAQPQSTVRPEEIPPI 280
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 73.2 bits (178), Expect = 1e-12
Identities = 62/268 (23%), Positives = 110/268 (41%), Gaps = 29/268 (10%)
Query: 668 PSSSSSASSSSESDSSDSDSDSSDS-SSESSSEESDSSSISSHSSASANDVRKKGHG--- 723
P S S S+ DS S+S+ DS + SS E D + + + ++ HG
Sbjct: 571 PEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERD 630
Query: 724 ----KTRSKEVDKLIRNQQTNDRKQKERRQEHGH----------------QETRTERERR 763
+ R + IR+Q ND +++ R+E +E +RER
Sbjct: 631 RRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERE 690
Query: 764 SEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKR 823
E+ R+++ R+ + +++ E+ DRD + + E + K++
Sbjct: 691 RERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750
Query: 824 GERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSD---EDRYQNGAERRWE 880
ER E E+ R ++ E R + R + KE R+ D +DR + E R +
Sbjct: 751 REREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRED 810
Query: 881 KSSRYSEQSRESKKNQDRRREKSPAKQK 908
++ R R+SKK R E SP+ ++
Sbjct: 811 RNPRDGHDERKSKKRY--RNEGSPSPRQ 836
Score = 53.5 bits (127), Expect = 9e-07
Identities = 55/241 (22%), Positives = 95/241 (39%), Gaps = 20/241 (8%)
Query: 667 SPSSSSSASSSSESDSSDSDSDSSDSSSESSSEE----------SDSSSISSHSSASAND 716
SP SS SSSS+S SS S + S +S SHS +S
Sbjct: 325 SPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQ- 383
Query: 717 VRKKGHGKTRSKEVDK----LIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNS 772
RK+ + RS +K R Q++DR+ + R G ++ + E +DQ+S
Sbjct: 384 -RKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 773 SGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSE 832
S + D + D+ + + + + RD ++ + D K+ R + R+S S
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESR-DPRDSRST 501
Query: 833 NEKHTHRIKDSENFRRKDRS---KSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQS 889
+ H +R ++ + RK+ + +S+ R H S +N + R
Sbjct: 502 RDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMG 561
Query: 890 R 890
R
Sbjct: 562 R 562
Score = 51.6 bits (122), Expect = 3e-06
Identities = 68/321 (21%), Positives = 123/321 (38%), Gaps = 63/321 (19%)
Query: 644 REHLKNTPKVIVAQK--PDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEES 701
+E+++ ++I+ ++ P+V ++K SPS S SS S S S S+ +S S
Sbjct: 182 QENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVS 241
Query: 702 DSSSISSHSSASANDVRKKGH---------------GKTRSKEVDKLIRNQQTNDRKQKE 746
S + ++ N +KKG GK + KE K+ + R K+
Sbjct: 242 -SPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGK-KYKEKYKVKDRIEEKTRDGKD 299
Query: 747 RRQEHGHQETRTERERR------------SEKHRDQNSSGSNW----------RDPITKY 784
R ++ Q + ++ R S H + SGS+ R P Y
Sbjct: 300 RGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSY 359
Query: 785 TSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGER---RNSFSENEKHTHRIK 841
P R+ ++ +H P +++G R S S + +H R
Sbjct: 360 QRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERRED 419
Query: 842 D-SENFRRKDRSKSKEMNRKHSGSRS--DEDRYQNGAERRWEKSSR-------------- 884
+ R KD + +E + S SR D+ ++G +RR + +R
Sbjct: 420 TRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDS 479
Query: 885 --YSEQSRESKKNQDRRREKS 903
+ SR++K+++D R +S
Sbjct: 480 REMRDYSRDTKESRDPRDSRS 500
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 18/106 (16%)
Query: 2 KSSVAQIKP-----SSGHDRRENLNSYQRNSSPEDRYEEQERS----------PRDRDYF 46
KS + Q+K S+ DR+++ + R SSPE + RS RDR
Sbjct: 1248 KSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEH 1307
Query: 47 DYSRSDYEHSRRGRSYDSSMES---RNRDREKRRERERDTDRKRSR 89
D R R R +D + RNRDR++ RERER+ +R + R
Sbjct: 1308 DRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 17 RENLNSYQRNSSPE-DRYEEQERS---PRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRD 72
RE +R + E +R E+ER RDRD+ D R R + + E R R+
Sbjct: 701 REKERELERERAREREREREKERDRERDRDRDH-DRERERERERDREKEREREREERERE 759
Query: 73 REKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
RE+ RERER+ +R+R R R + +D+ K+++
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREE 806
Score = 45.4 bits (106), Expect = 2e-04
Identities = 59/259 (22%), Positives = 104/259 (40%), Gaps = 19/259 (7%)
Query: 650 TPKVIVA----QKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSS 705
TP V + +KP ++ SS S+ S S + +DS+ S + S
Sbjct: 1170 TPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLH 1229
Query: 706 ISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSE 765
S + G K+R +D+L R + + +R+ H R+ E +
Sbjct: 1230 SGSRDREKTKSLEITGERKSR---IDQLKRGEPSRS-TSSDRQDSRSHSSRRSSPESDRQ 1285
Query: 766 KHRDQNSSGSNWR-DPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLEN-----KHGDP 819
H S S R +Y D++ ER + + DRD + + +
Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERER 1345
Query: 820 KKKRGERRNSFSENEKHTHRIKDS-ENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERR 878
+++R +RR+ E E+ I DS E R +DR ++ E ++ S R E + + ER
Sbjct: 1346 ERERDKRRDLDRERER---LISDSVERDRDRDRDRTFESSQIESVKRC-EAKLEGEHERD 1401
Query: 879 WEKSSRYSEQSRESKKNQD 897
E +SR S + + ++D
Sbjct: 1402 LESTSRDSLALDKERMDKD 1420
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 11/84 (13%)
Query: 19 NLNSYQRNSSPEDRYEEQERSP-RDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRR 77
+L+S QR SP + RSP R++ D+ R+ H RR + + R+R+++ R
Sbjct: 378 SLSSPQRKQSPP-----RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSRE 432
Query: 78 ERERDTDRKRSR-----KSPSPGR 96
ERE + D+ SR + P GR
Sbjct: 433 EREYEQDQSSSRDHRDDREPRDGR 456
Score = 41.2 bits (95), Expect = 0.004
Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 29/135 (21%)
Query: 15 DRRENLNSYQRNSSP---EDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSME---- 67
DRR+N QR SSP + R +E ER R R+ R D R R D E
Sbjct: 630 DRRDNRERDQRPSSPIRHQGRNDELERDER-REERRVDRVDDRRDERARERDRERERDRE 688
Query: 68 ---------------------SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQS 106
R R+RE+ RE+ERD +R R R R E +
Sbjct: 689 RERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKE 748
Query: 107 SSAQDEPATKKKKDE 121
+ E ++++ E
Sbjct: 749 REREREERERERERE 763
Score = 41.2 bits (95), Expect = 0.004
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSR-----RGRSYDSSME-- 67
DRR+ + DR E+ER R+RD + E R R R + E
Sbjct: 670 DRRDERARERDRERERDRERERERE-RERDREREKERELERERAREREREREKERDRERD 728
Query: 68 -SRNRDREKRRERERDTDRKRSRKSPSPGR-RNPETSVTQSSSAQDEPATKKKKD 120
R+ DRE+ RERERD +++R R+ R R E + + E A ++ K+
Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE 783
Score = 41.2 bits (95), Expect = 0.004
Identities = 46/231 (19%), Positives = 94/231 (40%), Gaps = 22/231 (9%)
Query: 692 SSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKL----IRNQQTNDRKQKER 747
++S S+S + S+S + ++ + + H K V+K+ + + RK ++
Sbjct: 1127 ATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQ 1186
Query: 748 RQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQE 807
++ R+ R S + R ++ + + S D + + DR++
Sbjct: 1187 KRSSSLGSNRSNRSHTSGRLRSPSNDSA--------HRSGDDQSGRKRVLHSGSRDREKT 1238
Query: 808 MHIDL--ENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSR 865
+++ E K + KRGE S S + + + + DR S R
Sbjct: 1239 KSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDR 1298
Query: 866 SDE-DRYQNGAERRWEK-SSRYSEQSRESKKN------QDRRREKSPAKQK 908
E DRY++ ER E+ +R E R++ K+ +DR RE+ +++
Sbjct: 1299 LQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERER 1349
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/210 (19%), Positives = 88/210 (41%), Gaps = 37/210 (17%)
Query: 693 SSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHG 752
SS S S+ S S + +ND H + K + + + DR++ + + G
Sbjct: 1189 SSSLGSNRSNRSHTSGRLRSPSND---SAHRSGDDQSGRKRVLHSGSRDREKTKSLEITG 1245
Query: 753 HQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDL 812
+++R ++ +R E R +S + R ++ +S + S+R +SR + D +
Sbjct: 1246 ERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPE---SDRQVHSR-SGSFDSRDRLQE 1301
Query: 813 ENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQ 872
+++ +++ ERR++ ++ R D + R +DR + +E R
Sbjct: 1302 RDRYEHDRERERERRDT---RQREWDRDADKDWPRNRDRDRLRERER------------- 1345
Query: 873 NGAERRWEKSSRYSEQSRESKKNQDRRREK 902
E+ R+ +++ DR RE+
Sbjct: 1346 --------------ERERDKRRDLDRERER 1361
Score = 40.0 bits (92), Expect = 0.010
Identities = 47/232 (20%), Positives = 91/232 (39%), Gaps = 10/232 (4%)
Query: 675 SSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLI 734
S S+ SD DS S SS SS S + S S S S + + H + R +E
Sbjct: 1260 SRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR 1319
Query: 735 RNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKD----- 789
+ + D + R + ERER +K RD + + D+D
Sbjct: 1320 QREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTF 1379
Query: 790 VPSERNNYSRVANDRDQEMHIDLENKHGDP---KKKRGERRNSFSENEKHTHRIKDSENF 846
S+ + R + E DLE+ D K+R ++ + + T++ + +E+
Sbjct: 1380 ESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESL 1439
Query: 847 RRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDR 898
D +++ HS + Y+ ++ ++ + RE ++++++
Sbjct: 1440 EAGD--DESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEK 1489
Score = 39.7 bits (91), Expect = 0.013
Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 35/140 (25%)
Query: 11 SSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRR------------ 58
S+ HD E +SY DRY E++ + RD + R E RR
Sbjct: 590 SNYHDSWETRSSYPER----DRYPERDNRDQARD-SSFERRHGERDRRDNRERDQRPSSP 644
Query: 59 ----GRSYDSSMESR--------------NRDREKRRERERDTDRKRSRKSPSPGRRNPE 100
GR+ + + R R RE+ RERERD +R+R R+ R E
Sbjct: 645 IRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKE 704
Query: 101 TSVTQSSSAQDEPATKKKKD 120
+ + + + E +K++D
Sbjct: 705 RELERERAREREREREKERD 724
Score = 38.1 bits (87), Expect = 0.037
Identities = 32/117 (27%), Positives = 46/117 (39%), Gaps = 5/117 (4%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
+R E +R E E + R+RD + D+E +GR D E R RE
Sbjct: 752 EREERERERERERERERERERERERARERDKERERQRDWEDKDKGR--DDRREKREEIRE 809
Query: 75 KRRERERDTDRK---RSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTR 128
R R+ +RK R R SP R + S D + K+E LL++
Sbjct: 810 DRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQ 866
Score = 37.0 bits (84), Expect = 0.083
Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 12/128 (9%)
Query: 3 SSVAQIKPSSGHDRRENLNSYQRNSSPEDRYE--EQERSPRDRDYFDYSRSDYEHS---- 56
SS + + S G R + + +PE E E E + D D D + DY H
Sbjct: 109 SSPVRKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINY-DYVHELSLE 167
Query: 57 -RRGRSYDSSMESRNRDREKRRE----RERDTDRKRSRKSPSPGRRNPETSVTQSSSAQD 111
+R + M+ + EKR E +E + RS+ SPSP R S + SS +
Sbjct: 168 MKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKS 227
Query: 112 EPATKKKK 119
A+KK +
Sbjct: 228 SSASKKDR 235
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 6/104 (5%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
DR + + + DR +E+ER +R+ R R R + E R R+R+
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERE-----RERERERERERERERERE-RARERD 781
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
K RER+RD + K + +R DE +KK+
Sbjct: 782 KERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKR 825
Score = 35.8 bits (81), Expect = 0.19
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 13/108 (12%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
R ++S+ NS+ D +E + P +RD + E R ++ DSS E R+ +R++
Sbjct: 579 RGSQIDSHSSNSNYHDSWETRSSYP-ERDRYP------ERDNRDQARDSSFERRHGERDR 631
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
R +R+R ++ SP R + ++E + D D
Sbjct: 632 R------DNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRD 673
Score = 35.8 bits (81), Expect = 0.19
Identities = 54/244 (22%), Positives = 88/244 (36%), Gaps = 30/244 (12%)
Query: 663 QNKSSPSSSSSASSSSESDSSDSDS-DSSDSSSESSS------EESDSSSIS-SHSSASA 714
+N+ SPS S E S DSD+ +S D +E +S S+S SH +
Sbjct: 827 RNEGSPSPRQSPKRRREH-SPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR 885
Query: 715 NDVRKKGHGKTRSKEVDKLIRNQQTNDRKQ---KERRQEH-------------GHQETRT 758
K+ K KE + Q+ ++ K+R Q GH ++
Sbjct: 886 QGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSE- 944
Query: 759 ERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGD 818
+RE H + + PI K D DV ER N + D + K
Sbjct: 945 DRETSDRAHDENKKKAKIQKKPIKKKKED-DVGIERGNIETTSEDGQVFSPKKGQKKKSI 1003
Query: 819 PKKKRGERRNSFSENEKHTHRIKDSENFRR---KDRSKSKEMNRKHSGSRSDEDRYQNGA 875
KK++ + +S +E+ + K R + + EM +G D + ++ A
Sbjct: 1004 EKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTA 1063
Query: 876 ERRW 879
W
Sbjct: 1064 FSDW 1067
Score = 34.3 bits (77), Expect = 0.54
Identities = 30/128 (23%), Positives = 48/128 (37%), Gaps = 15/128 (11%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K DRRE + + +P D ++E++ R R+ S RR S DS +
Sbjct: 793 KDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYN 852
Query: 69 RNRDREKRRERERDTDRKRSRKSPSPGR-------------RNPETSVTQSSSAQDEPAT 115
D+ ++ R + +S SP R PE +SS +E
Sbjct: 853 SGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERK--ESSRRYEEQEL 910
Query: 116 KKKKDELD 123
K+K +D
Sbjct: 911 KEKVSSVD 918
Score = 33.9 bits (76), Expect = 0.71
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 8/116 (6%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
+P G DRR+ ++ R + R R R DYSR D + SR R S+ ++
Sbjct: 451 EPRDGRDRRDARDTRDRRELRDSRDMRDSREMR-----DYSR-DTKESRDPRDSRSTRDA 504
Query: 69 RN-RDREKR-RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDEL 122
+ RDRE R R+ DT + SR R + + +++E ++ + D +
Sbjct: 505 HDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRM 560
Score = 33.9 bits (76), Expect = 0.71
Identities = 39/199 (19%), Positives = 75/199 (37%), Gaps = 28/199 (14%)
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQT-----NDRKQKERRQEHGHQETRTERERRSEKHRDQ 770
D K G+ +E + IR + ++RK K+R + G R +RR E D
Sbjct: 789 DWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDS 848
Query: 771 NSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSF 830
++ Y S D + S+V + E++ P +R+ +
Sbjct: 849 DA-----------YNSGDDKNEKHRLLSQVVRPQ--------ESRSLSPSHLTEDRQGRW 889
Query: 831 SENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSR 890
E ++ R E+ RR + + KE R + ++ R + + + R
Sbjct: 890 KEEDRKPER---KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDR 946
Query: 891 E-SKKNQDRRREKSPAKQK 908
E S + D ++K+ ++K
Sbjct: 947 ETSDRAHDENKKKAKIQKK 965
Score = 33.5 bits (75), Expect = 0.92
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 11/123 (8%)
Query: 3 SSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSY 62
SS+ + PS R + SYQR +P R + SP Y +S S + + +
Sbjct: 340 SSIQRHSPSPRRKRTPS-PSYQRTLTPPLR---RSASP----YPSHSLSSPQRKQSPPRH 391
Query: 63 DSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPE-TSVTQSSSAQDEPATKKKKDE 121
S M + R +R + D R+ R+ + G+R+ E S + QD+ +++ +D+
Sbjct: 392 RSPMREKGRHDHERTSQSHD--RRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDD 449
Query: 122 LDP 124
+P
Sbjct: 450 REP 452
Score = 32.7 bits (73), Expect = 1.6
Identities = 26/115 (22%), Positives = 43/115 (37%), Gaps = 10/115 (8%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
+ S HDRR ++R + + ++ S +R+Y S +H D
Sbjct: 405 RTSQSHDRR-----HERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRR 459
Query: 69 RNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
RD RRE D + SR+ R+ +S +D +T+ D D
Sbjct: 460 DARDTRDRRELRDSRDMRDSRE-----MRDYSRDTKESRDPRDSRSTRDAHDYRD 509
Score = 31.6 bits (70), Expect = 3.5
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYF-DYSRSDYEHSRRGRSYDSSMESRNRDR 73
+R + + + DR E+ER RDR+ + R + E R R R+R
Sbjct: 718 EREKERDRERDRDRDHDRERERERE-RDREKEREREREERERERERERERERERERERER 776
Query: 74 EKRRERERDTDRKRSRKSPS-PGRRNPETSVTQSSSAQDEPATKKKK 119
+ R++ER+ R K RR + + + +D +K K
Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823
Score = 30.8 bits (68), Expect = 6.0
Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 24/132 (18%)
Query: 14 HDR-----RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
HDR RE +R E+R E+ER + R + R E
Sbjct: 733 HDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWED 792
Query: 69 RNRDREKRRERERDT----------DRKRSRK------SPSPGRRNPETSVTQS--SSAQ 110
+++ R+ RRE+ + D ++S+K SPSP R++P+ S S A
Sbjct: 793 KDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSP-RQSPKRRREHSPDSDAY 851
Query: 111 DEPATKKKKDEL 122
+ K +K L
Sbjct: 852 NSGDDKNEKHRL 863
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 71.6 bits (174), Expect = 3e-12
Identities = 67/245 (27%), Positives = 97/245 (39%), Gaps = 41/245 (16%)
Query: 665 KSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGH-- 722
KS S SS SS S+S S S S S S S+ S S S R + H
Sbjct: 203 KSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA 262
Query: 723 GKTRSKEVDKLIRNQQTNDRKQKER-RQEHGHQETRTERERRSEKHRDQNSSGSNWRDPI 781
GK+RSK D+ Q ND K + R H+ R R E+ ++ GS
Sbjct: 263 GKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS------ 316
Query: 782 TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIK 841
V+ R QE L + K G R S S ++ K
Sbjct: 317 ------------------VSRGRSQEK--SLRQSRSRSRSKGGSRSRSRSRSKS-----K 351
Query: 842 DSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRRE 901
D +RK R +S+E +R S SRS +R + +R S+ ++ K++ DR +
Sbjct: 352 D----KRKGRKRSREESRSRSRSRSKSERSRKRGSKR---DSKAGSSKKKKKEDTDRSQS 404
Query: 902 KSPAK 906
+SP++
Sbjct: 405 RSPSR 409
Score = 60.8 bits (146), Expect = 5e-09
Identities = 57/252 (22%), Positives = 107/252 (42%), Gaps = 25/252 (9%)
Query: 663 QNKSSPSSSSSASSSSESDSSDSDS-DSSDSSSESSSEESDSSSISSHSSASANDVRKKG 721
Q++S S S S E S S S S S S+ +EE ++ + S + R K
Sbjct: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS 296
Query: 722 HGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPI 781
K+RS R+Q+ ++K G + ++ R+ RS R ++ GS R
Sbjct: 297 KSKSRS-------RSQERRVEEEKRGSVSRGRSQEKSLRQSRS---RSRSKGGSRSRSRS 346
Query: 782 TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIK 841
+ DK +R+ R++ + +KRG +R+S + + K + +
Sbjct: 347 RSKSKDKRKGRKRS--------REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK-E 397
Query: 842 DSENFRRKDRSKSKEMNRKHSGSRSDE-----DRYQNGAERRWEKSSRYSEQSRESKKNQ 896
D++ + + S+S R+H+ S S + + G + SR + +S+ + ++
Sbjct: 398 DTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSE 457
Query: 897 DRRREKSPAKQK 908
R R KS +K +
Sbjct: 458 SRSRSKSASKTR 469
Score = 47.8 bits (112), Expect = 5e-05
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERS--PRDRDYFDYSRSDYEHSRRGRSYDSSM 66
KP S R S R+ S E R EE++R R R R SR S
Sbjct: 285 KPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS 344
Query: 67 ESRNRDREKRRERERDTDRKRSR-KSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPL 125
SR++ ++KR+ R+R + RSR +S S R+ + + S A + KKKK++ D
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS--SKKKKKEDTDRS 402
Query: 126 LTRT 129
+R+
Sbjct: 403 QSRS 406
Score = 43.9 bits (102), Expect = 7e-04
Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 2/147 (1%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
+Q+ + Q++S S + S S S S D S S S S S
Sbjct: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRG 381
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
R G ++ K+ + R+Q + + + +EH E+ ++RE R E + +
Sbjct: 382 SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES-SQREGRGESENAGTNQET 440
Query: 776 NWRDPITKYTSDKDVPSERNNYSRVAN 802
R + S ++PSE + S+ A+
Sbjct: 441 RSRSR-SNSKSKPNLPSESRSRSKSAS 466
Score = 40.8 bits (94), Expect = 0.006
Identities = 34/167 (20%), Positives = 64/167 (38%), Gaps = 1/167 (0%)
Query: 1 MKSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGR 60
MK ++ ++ + + R+ L + S Y R R +SR S +
Sbjct: 153 MKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSK 212
Query: 61 SYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
S S SR+R + R + R + RSR S R+P ++S S + K KD
Sbjct: 213 SSHSKSRSRSRSGSRSRSKSRSRSQSRSR-SKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
Query: 121 ELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSIN 167
+ + + P ++ + + S + +R E + S++
Sbjct: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVS 318
Score = 40.0 bits (92), Expect = 0.010
Identities = 50/216 (23%), Positives = 87/216 (40%), Gaps = 36/216 (16%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSS--ESDSSDSDSDSSDSSSESSSEESDSSSISSHSSAS 713
+Q+ VE+ K S + S +S S S S S S S+ D
Sbjct: 304 SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD----------- 352
Query: 714 ANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSS 773
K G+ RS+E + ++ R + ER ++ G + R + S+K + +++
Sbjct: 353 ------KRKGRKRSREESR----SRSRSRSKSERSRKRGSK--RDSKAGSSKKKKKEDTD 400
Query: 774 GSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSE- 832
S R P + V ER + ++ R E + EN + + + R NS S+
Sbjct: 401 RSQSRSP------SRSVSKEREHAKSESSQR--EGRGESENAGTNQETRSRSRSNSKSKP 452
Query: 833 --NEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS 866
+ R K + R + +S+S+ +R S SRS
Sbjct: 453 NLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRS 488
Score = 37.0 bits (84), Expect = 0.083
Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 7/104 (6%)
Query: 812 LENKHGDPKKKRGERRNSFSENE-------KHTHRIKDSENFRRKDRSKSKEMNRKHSGS 864
+E+K G +++ R S S + K R S++ K RS+S+ +R S S
Sbjct: 173 VEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKS 232
Query: 865 RSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
RS + + S+ +SR + R + K A++K
Sbjct: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK 276
Score = 33.5 bits (75), Expect = 0.92
Identities = 22/87 (25%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 826 RRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKS--- 882
R+ E++ + R + R RS+S+ + + S SRS + + R +S
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 883 SRYSEQSR-ESKKNQDRRREKSPAKQK 908
SR +SR +S+ + + +SP+K+K
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEK 254
Score = 32.3 bits (72), Expect = 2.1
Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 11/88 (12%)
Query: 27 SSPEDRYEEQERSPRDRDYFDYSRSDYEHSR-RGRSYDSSMESRNRDREKRRERERDTDR 85
S +D+ + ++RS + SRS E SR RG DS S +++++ DTDR
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS------SKKKKKEDTDR 401
Query: 86 KRSRKSPSPGRR-NPETSVTQSSSAQDE 112
+SR SP R + E +S S+Q E
Sbjct: 402 SQSR---SPSRSVSKEREHAKSESSQRE 426
Score = 31.6 bits (70), Expect = 3.5
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 9/111 (8%)
Query: 2 KSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRD-RDYFDYSRSDYEHSRRGR 60
K+ ++ K DR ++ S R+ S E + + E S R+ R + + ++ E R R
Sbjct: 387 KAGSSKKKKKEDTDRSQS-RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSR 445
Query: 61 SYDSS---MESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSS 108
S S + S +R R K + R + RSR + R+P S ++S S
Sbjct: 446 SNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS----RSPSRSRSRSHS 492
Score = 30.8 bits (68), Expect = 6.0
Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 8/93 (8%)
Query: 821 KKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSR-----SDEDRYQNGA 875
K+ E+ + N + ++D RR+ +S +R HS SR S + R ++G+
Sbjct: 154 KRALEKLDGTEVNGRKIRLVEDKPGSRRR---RSYSRSRSHSRSRSRSRHSRKSRSRSGS 210
Query: 876 ERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ SR +S +++ R R +S ++ K
Sbjct: 211 SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSK 243
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 71.6 bits (174), Expect = 3e-12
Identities = 55/222 (24%), Positives = 96/222 (43%), Gaps = 19/222 (8%)
Query: 700 ESDSSSISSHSSASANDVRKKGHGKTRSKEVDKL-IRNQQTNDRKQKERRQEHGHQETRT 758
E D + S + D KK + KE ++ I ++ +++ER +E +E
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 759 ERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDL-ENKHG 817
ERER EK +++ RD D+D ER+ DRD+E D +++
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERD------RDRDRERSSDRNKDRSR 383
Query: 818 DPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAER 877
+K R R E E+ R ++ E R ++R + +E R+ R E+ ++ ER
Sbjct: 384 SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 878 R------WEKSSRYSE-----QSRESKKNQDRRREKSPAKQK 908
R EK + Y E + RE KK ++ +E +++
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Score = 67.4 bits (163), Expect = 6e-11
Identities = 73/355 (20%), Positives = 143/355 (40%), Gaps = 17/355 (4%)
Query: 561 PWSVLECIKLSEETTTSSSRIFVKIFFQ---ELCEYMGLPKL-NARLKDETLQPFFEGLL 616
P S L ++L + ++ VK+ + +L E+ K N + ET+ E L
Sbjct: 137 PESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEAL 196
Query: 617 PRDNPRNTRF---AINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQN-KSSPSSSS 672
+ R + AI L +E + K +K D+ + +P
Sbjct: 197 DEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPY 256
Query: 673 SASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDK 732
+ + ++ + + D D S S+ D+ R++ + R +E ++
Sbjct: 257 PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERER 316
Query: 733 LIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPS 792
R ++ +R+++ R+ +E ERER ++ RD+ RD D++ S
Sbjct: 317 E-RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS 375
Query: 793 ERN----NYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRR 848
+RN + DR++E + E + + +++R R E E+ R KD + R
Sbjct: 376 DRNKDRSRSREKSRDRERERERERERER-EREREREREREREREREREREREKDKKRDRE 434
Query: 849 KDRSKSKEMNRKHSGSRSDEDRYQNGAERRWE--KSSRYSEQSRESKKNQDRRRE 901
+D + E + R E YQ + WE + + E +E+++ ++RRRE
Sbjct: 435 EDEEDAYERRKLERKLREKEAAYQERL-KNWEIRERKKTREYEKEAEREEERRRE 488
Score = 57.4 bits (137), Expect = 6e-08
Identities = 54/256 (21%), Positives = 99/256 (38%), Gaps = 41/256 (16%)
Query: 684 DSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRK 743
D D D + E D SS D R + K+R +E ++ ++ +R+
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKD-RSRSREKSRDRERERERERERERERE 406
Query: 744 QKERRQEHGHQETRTERERRSEKHRDQNSSGS------------------------NW-- 777
++ R+ +E ERER +K RD+ NW
Sbjct: 407 REREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 466
Query: 778 --RDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGER-RNSFSENE 834
R +Y + + ER R +E D ++ DPK RG + + E
Sbjct: 467 RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 526
Query: 835 KHTHRIKDSENFRRKDRSKSKEMNRK-----HSGSRSDEDRYQNGAERRWE---KSSRYS 886
K ++ E R++++ + +E+ ++ H ++ R + AERR + K S
Sbjct: 527 K---EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPES 583
Query: 887 EQSRESKKNQDRRREK 902
E+ E K+ ++ +RE+
Sbjct: 584 EEEEEEKQEKEEKREE 599
Score = 51.6 bits (122), Expect = 3e-06
Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 7/149 (4%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSR-RGRSYDSSMES-RNRD 72
+RRE +R E E + RDRD D + R R R D S RN+D
Sbjct: 321 ERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Query: 73 REKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTGGA 132
R + RE+ RD +R+R R+ R E + + E +++KD+ A
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Query: 133 YIPPAKLRMMQEQITDKNSLAYQRM-SWE 160
Y + R ++ ++ +K + +R+ +WE
Sbjct: 441 Y----ERRKLERKLREKEAAYQERLKNWE 465
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDT 83
+R +R E+ER R+R+ + E R R ++R++ R+RERD
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 84 DRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
DR R R S RN + S ++ S E +++++
Sbjct: 368 DRDRERSSD----RNKDRSRSREKSRDRERERERERE 400
Score = 42.7 bits (99), Expect = 0.002
Identities = 47/261 (18%), Positives = 95/261 (36%), Gaps = 31/261 (11%)
Query: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRK 719
D ++++ S + S S S D + + E + + R+
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE-RE 424
Query: 720 KGHGKTRSKEVD--------KLIRNQQTNDRKQKER------RQEHGHQETRTERERRSE 765
+ K R +E D KL R + + +ER R+ +E E ER E
Sbjct: 425 REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEE 484
Query: 766 KHRDQNSSGSNWRDPITKYTSDKDVPS--ERNNYSRVANDRDQEMHIDLENKHGDPKKKR 823
+ R+ ++ + Y D+D P + + DR++EM D ++ + ++
Sbjct: 485 RRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELE 544
Query: 824 GERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSS 883
R+ +E H D+E R + ++ + + S+E+ E+
Sbjct: 545 EIRQRLLAEG----HPDPDAELQRMEQEAERRRQPQIKQEPESEEE----------EEEK 590
Query: 884 RYSEQSRESKKNQDRRREKSP 904
+ E+ RE ++ E+ P
Sbjct: 591 QEKEEKREEPMEEEEEPEQKP 611
Score = 41.6 bits (96), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Query: 11 SSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRN 70
S D + L + E + E+ER R+R+ + E RR R + E R
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERE------RERERERRERERERERE-RE 334
Query: 71 RDREKRRERERDTDRKRSRKSPSPGRRNPE 100
R++EK RERER+ DR R R R+ E
Sbjct: 335 REKEKERERERERDRDRDRTKERDRDRDRE 364
Score = 39.3 bits (90), Expect = 0.017
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 15/115 (13%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSR-RGRSYDSSMESRNRDR 73
+RRE +R +R E+ER R+R+ + E R R R D + E R+RDR
Sbjct: 308 ERRERERERERERERRERERERERE-RERE----KEKERERERERDRDRDRTKE-RDRDR 361
Query: 74 EKRRERERD--------TDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
++ R+R+RD DR RSR+ R E + + E +++++
Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERE 416
Score = 32.0 bits (71), Expect = 2.7
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 24/128 (18%)
Query: 17 RENLNSYQRNSSPED--RYEEQERSPRDRDY---FDYSRSDYEHSR------RGRSYDSS 65
R+ Y++ + E+ R E + + R +++ +D R D ++ R R R +
Sbjct: 469 RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528
Query: 66 MESRNRDREKRRE-----RER-------DTDRKRSRKSPSPGRRNPETSVTQSSSAQDEP 113
ME+ RDR++ +E R+R D D + R RR + + Q +++E
Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRR-QPQIKQEPESEEEE 587
Query: 114 ATKKKKDE 121
K++K+E
Sbjct: 588 EEKQEKEE 595
Score = 31.6 bits (70), Expect = 3.5
Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 384 VFKMDPNFMENEE-KYKAIKKEILDEGDTDSNTDQDAGSSEEDEEEEEEEGEEDE 437
+ K D N +E EE K I +EI DT +++ G E++ +E E+E E E
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERE 313
Score = 31.2 bits (69), Expect = 4.6
Identities = 20/107 (18%), Positives = 44/107 (41%), Gaps = 5/107 (4%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
+E++N+ + D + RD + + + E ++ + +E R+RE+
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDT----HKKLEEEKGKKEKERQE-IEKERRERERE 315
Query: 77 RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
RERER+ + + R + + +D TK++ + D
Sbjct: 316 RERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD 362
Score = 31.2 bits (69), Expect = 4.6
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 7/106 (6%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
DR ++ + + S +R E+ER R+R+ R R R + E R R+++
Sbjct: 376 DRNKDRSRSREKSRDRERERERERE-RERE-----RERERERERERERERERE-REREKD 428
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
K+R+RE D + R+ R E + + + KK ++
Sbjct: 429 KKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTRE 474
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 69.3 bits (168), Expect = 2e-11
Identities = 60/248 (24%), Positives = 110/248 (44%), Gaps = 25/248 (10%)
Query: 665 KSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGK 724
+ SP S S S E S S + E E ++ S + R +
Sbjct: 270 RRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRR 329
Query: 725 TRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKY 784
+RS+E + ++ DRK R ++ +E E ER + RD + N R+
Sbjct: 330 SRSRERHR--SRSRSRDRKGDRRDRD---REREKENERGRRRDRDYDKERGNERE----- 379
Query: 785 TSDKDVPSERNNYSRVANDRDQEMHIDLEN--KHGDPKK-KRGERRNSFSENEKHTHRIK 841
+++ ER+ R + +++ H + ++ +H D K+ + E+++S S + + HR +
Sbjct: 380 -KERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSR 438
Query: 842 D-SENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRR 900
S N ++ RS+SKE + KH +N ++ + K SR Q R + ++R
Sbjct: 439 SRSRNAGKRSRSRSKEKSSKH----------KNESKEKSNKRSRSGSQGRTDSVEKSKKR 488
Query: 901 EKSPAKQK 908
E SP+K+K
Sbjct: 489 EHSPSKEK 496
Score = 58.5 bits (140), Expect = 3e-08
Identities = 64/300 (21%), Positives = 115/300 (38%), Gaps = 39/300 (13%)
Query: 615 LLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSP------ 668
L PR +PR +R + G EL + A++ + E+ +S
Sbjct: 267 LSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLE 326
Query: 669 --SSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTR 726
S S S S S D D D E E + R+K ++R
Sbjct: 327 RRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSR 386
Query: 727 SKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTS 786
+ ++ R + ++K KE + + H++ + R S+K + + S S R K+ S
Sbjct: 387 ERSKEQRSRGE-VEEKKHKEDKDDRRHRDDK----RDSKKEKKHSRSRSRER----KHRS 437
Query: 787 DKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERR---------NSFSENEKHT 837
+ SR A R + + +KH + K++ +R +S +++K
Sbjct: 438 --------RSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489
Query: 838 HRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
H E R++ RSK + R HS S+ D++ +RR +S Q ++ K +
Sbjct: 490 HS-PSKEKSRKRSRSKERSHKRDHSDSKDQSDKH----DRRRSQSIEQESQEKQHKNKDE 544
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/202 (21%), Positives = 81/202 (40%), Gaps = 30/202 (14%)
Query: 720 KGHGKTRSKEVDKLIRNQQTND--------------RKQKERRQEHGHQETRTERERRSE 765
K GK ++E+D+ + +++ R + R+ HG E ER E
Sbjct: 241 KKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE 300
Query: 766 KHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGE 825
+ R + + ++ + D+ + R+ R +E H + ++G+
Sbjct: 301 RQRLEREAKEREKERRRSRSIDRGLERRRS--------RSRERH----RSRSRSRDRKGD 348
Query: 826 RRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSS-- 883
RR+ E EK R + + K+R +E R+ S RS E R + E + K
Sbjct: 349 RRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 884 --RYSEQSRESKKNQDRRREKS 903
R+ + R+SKK + R +S
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRS 430
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/123 (32%), Positives = 54/123 (43%), Gaps = 12/123 (9%)
Query: 11 SSGHDRR-ENLNSYQRNSSPEDRYEEQERSPRDRDYF---DYSRSDYEHSRRGRSYDSSM 66
SS DR E QR E++ R R D SRS H R RS D
Sbjct: 288 SSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKG 347
Query: 67 ESRNRDREKRRE------RERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+ R+RDRE+ +E R+RD D++R + R+ E S Q S + E KK K+
Sbjct: 348 DRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVE--EKKHKE 405
Query: 121 ELD 123
+ D
Sbjct: 406 DKD 408
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 11/114 (9%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSR----------RGRSYDSS 65
R + R E +++E + R RD S+ + +HSR R RS ++
Sbjct: 386 RERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAG 445
Query: 66 MESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
SR+R +EK + + ++ K +++S S G + SV +S + P+ +K +
Sbjct: 446 KRSRSRSKEKSSKHKNESKEKSNKRSRS-GSQGRTDSVEKSKKREHSPSKEKSR 498
Score = 41.2 bits (95), Expect = 0.004
Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 25 RNSSPEDRYEEQERS-PRDRDYFDYSRSDYEHSRRGRSYDSSMESRNR----------DR 73
R +R +E ER RDRDY D R + R RS + S E R+R D+
Sbjct: 349 RRDRDREREKENERGRRRDRDY-DKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407
Query: 74 EKRRERERDTDRKRSRK-SPSPGRRNPETSVTQSSSAQDEPATKKKK 119
+ RR R+ D K+ +K S S R S ++S +A ++ K+
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKE 454
Score = 40.0 bits (92), Expect = 0.010
Identities = 39/134 (29%), Positives = 54/134 (40%), Gaps = 32/134 (23%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSP-----RDRDYFDYSRSDYEHSRRGRSYDSSMESRNR 71
R S R DR E+E+ RDRDY D R + R RS + S E R+R
Sbjct: 337 RSRSRSRDRKGDRRDRDREREKENERGRRRDRDY-DKERGNEREKERERSRERSKEQRSR 395
Query: 72 D------------------------REKRRERERDTDRK-RSR-KSPSPGRRNPETSVTQ 105
+EK+ R R +RK RSR +S + G+R+ S +
Sbjct: 396 GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455
Query: 106 SSSAQDEPATKKKK 119
SS ++E K K
Sbjct: 456 SSKHKNESKEKSNK 469
Score = 38.5 bits (88), Expect = 0.029
Identities = 24/110 (21%), Positives = 57/110 (51%), Gaps = 11/110 (10%)
Query: 665 KSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGK 724
K S S S SS +++S + + S S S+ ++ + S HS + ++K +
Sbjct: 446 KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS-----KEKSRKR 500
Query: 725 TRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRT-ERERRSEKHRDQNSS 773
+RSKE R+ + + K++ +H + +++ E+E + ++H++++ +
Sbjct: 501 SRSKE-----RSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDET 545
Score = 37.4 bits (85), Expect = 0.064
Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 8/106 (7%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRS-DYEHSRRGRSYDSSMES---RNRDRE--KRR 77
+R S DR E+ RS + SRS D + RR R + E+ R RDR+ K R
Sbjct: 315 RRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKER 374
Query: 78 ERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
ER+ +R+RSR+ R E V + +D+ + + D+ D
Sbjct: 375 GNEREKERERSRERSKEQRSRGE--VEEKKHKEDKDDRRHRDDKRD 418
Score = 35.0 bits (79), Expect = 0.32
Identities = 29/123 (23%), Positives = 46/123 (37%), Gaps = 18/123 (14%)
Query: 11 SSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYF-----------DYSRSDYEHSRRG 59
S +R+ S RN+ R +E+S + ++ R+D +
Sbjct: 428 SRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKK 487
Query: 60 RSYDSSME-SRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
R + S E SR R R K R +RD + + RR +QS + + K
Sbjct: 488 REHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRR------SQSIEQESQEKQHKN 541
Query: 119 KDE 121
KDE
Sbjct: 542 KDE 544
Score = 34.3 bits (77), Expect = 0.54
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 12/77 (15%)
Query: 14 HDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSME-SRNRD 72
H R S +R+ SP RSPR SRS + S+D +E + R
Sbjct: 254 HVERRRSRSPRRSLSPR-------RSPRR----SRSRSHHREGHGSSSFDRELEREKERQ 302
Query: 73 REKRRERERDTDRKRSR 89
R +R +ER+ +R+RSR
Sbjct: 303 RLEREAKEREKERRRSR 319
Score = 33.5 bits (75), Expect = 0.92
Identities = 27/130 (20%), Positives = 55/130 (42%), Gaps = 19/130 (14%)
Query: 2 KSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRS 61
+ S + + S H +S+ R E + ER ++R+ + RR RS
Sbjct: 270 RRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKERE---------KERRRSRS 320
Query: 62 YDSSMESR---------NRDREKRRERE-RDTDRKRSRKSPSPGRRNPETSVTQSSSAQD 111
D +E R +R R + R+ + RD DR+R +++ RR+ + + + +
Sbjct: 321 IDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREK 380
Query: 112 EPATKKKKDE 121
E +++ +
Sbjct: 381 ERERSRERSK 390
Score = 32.3 bits (72), Expect = 2.1
Identities = 28/125 (22%), Positives = 52/125 (41%), Gaps = 32/125 (25%)
Query: 814 NKHGDPKKKRGERR-----------------------NSFS---ENEKHTHRI----KDS 843
++H + ++ R RR +SF E EK R+ K+
Sbjct: 252 DRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKER 311
Query: 844 ENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKS 903
E RR+ RS + + R+ S SR +R+ ++ R ++ RE + + RRR++
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR--DREREKENERGRRRDRD 369
Query: 904 PAKQK 908
K++
Sbjct: 370 YDKER 374
Score = 31.6 bits (70), Expect = 3.5
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 9/98 (9%)
Query: 819 PKKKRGERRNSFSENEKHTHRIKDSENFRRK-------DRSKSKEMNRKHSGSRSDEDRY 871
P+K + + + E ++H R + S + RR RS+S+ +R+ GS S +
Sbjct: 237 PRKIKKDGKEGAEEIDRHVER-RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDREL 295
Query: 872 QNGAER-RWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ ER R E+ ++ E+ R ++ DR E+ ++ +
Sbjct: 296 EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSR 333
Score = 30.8 bits (68), Expect = 6.0
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 15/117 (12%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
R + +S + R E++ R R RS R RS + S + +N +EK
Sbjct: 413 RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS------RSRSKEKSSKHKNESKEK 466
Query: 76 RRERERD-----TD----RKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
+R R TD K+ SPS + + + S +D +K + D+ D
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHD 523
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 67.0 bits (162), Expect = 8e-11
Identities = 50/244 (20%), Positives = 109/244 (44%), Gaps = 22/244 (9%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHG 723
++ SP S + ++D D + D E + +E D D ++
Sbjct: 56 SQESPRSWGLGQAHKDADGDDRQRER-DRVREKTEKERD------------RDRKRDRER 102
Query: 724 KTRSKEVDK-LIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW----R 778
+ + KE ++ R +QT + +ER ++ G + R +R R E+ RD+ R
Sbjct: 103 RRKEKETNRNRDREKQTEIERDREREKQKGRERER-DRGRERERDRDREKERERQTEKDR 161
Query: 779 DPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLE-NKHGDPKKKRGERRNSFSENEKHT 837
D + ++++ ER +RD++ D E + ++R +R + +E ++ T
Sbjct: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRET 221
Query: 838 HRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
R + E RR++R + ++ ++ R ++ + ER+ E+ E+ +E K+ +D
Sbjct: 222 DREGERETDRRRERQRDRDRGKERDRERDRKE--ERKKERKKERKKERKEKKKEEKRRED 279
Query: 898 RRRE 901
++R+
Sbjct: 280 KKRK 283
Score = 64.3 bits (155), Expect = 5e-10
Identities = 45/206 (21%), Positives = 93/206 (45%), Gaps = 13/206 (6%)
Query: 708 SHSSASANDVRKKGHGKTRSK---EVDKLIRNQQTNDRKQKE-RRQEHGHQETRTERERR 763
+H A +D R++ + R K E D+ + + RK+KE R ++T ER+R
Sbjct: 68 AHKDADGDD-RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126
Query: 764 SEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKR 823
EK + + R+ ++D E+ + DRD + + E + ++K+
Sbjct: 127 REKQKGRERERDRGRE------RERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
Query: 824 GERRNSFS-ENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKS 882
ER + ++ T + ++ + R +DR + + R+ R E ER+ ++
Sbjct: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR- 239
Query: 883 SRYSEQSRESKKNQDRRREKSPAKQK 908
R E+ RE + ++R++E+ ++K
Sbjct: 240 DRGKERDRERDRKEERKKERKKERKK 265
Score = 47.4 bits (111), Expect = 6e-05
Identities = 29/108 (26%), Positives = 40/108 (37%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
RE R E E Q RDR + E R G R RDR++
Sbjct: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG 242
Query: 77 RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDP 124
+ER+R+ DRK RK R E + + E +K + + P
Sbjct: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/216 (15%), Positives = 86/216 (39%), Gaps = 17/216 (7%)
Query: 655 VAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASA 714
V +K + E+++ E++ + ++ + E+
Sbjct: 84 VREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRER 143
Query: 715 NDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSG 774
R + + R E D+ + + +R++ R++ +ET +R+R+ + +++
Sbjct: 144 ERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKER---- 199
Query: 775 SNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENE 834
++ ER+ + +R +E + E + D +++R R+ E +
Sbjct: 200 ------------ERQTDRERDRQRKTQTERQRETDREGE-RETDRRRERQRDRDRGKERD 246
Query: 835 KHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDR 870
+ R ++ + R+K+R K ++ +K R D+ R
Sbjct: 247 RERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/119 (21%), Positives = 54/119 (45%), Gaps = 7/119 (5%)
Query: 9 KPSSGHDRRENLNSYQRNSSPE---DRYEEQERSPRD----RDYFDYSRSDYEHSRRGRS 61
K + G DR+ + + + E DR ++ER ++ R+ +++ E R
Sbjct: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREK 129
Query: 62 YDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
R+R RE+ R+R+R+ +R+R + G+R ET + + + + ++D
Sbjct: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 31 DRYEEQER-SPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK--RRERERDTDRKR 87
DR +E+ER + +DRD + ++ E R R+RDR++ +ERER TDR+R
Sbjct: 148 DREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRER 207
Query: 88 SRKSPSPGRRNPET 101
R+ + R ET
Sbjct: 208 DRQRKTQTERQRET 221
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 31 DRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRK 90
DR E+ER DRD E R G+ + R+R+REK++ERE + DR R R
Sbjct: 138 DRGRERER---DRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Query: 91 SPSPGRRNPETSVTQSSSAQDE 112
+ R + + Q E
Sbjct: 195 TEKERERQTDRERDRQRKTQTE 216
Score = 36.6 bits (83), Expect = 0.11
Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYS----RSDYEHSRRGRSYDSSMESRNR 71
+RE +R+ E + E + RDR ++D E R+ ++ +R
Sbjct: 164 QRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Query: 72 D--REKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRT 129
+ RE R RER DR R ++ R E + + E KKK+++ R
Sbjct: 224 EGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Query: 130 GGAYIPP 136
G I P
Sbjct: 284 WGEGISP 290
Score = 33.9 bits (76), Expect = 0.71
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
RE Q + + E + RDR+ + E R R D+ E R R ++
Sbjct: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERDR-DRQRDTEKE-RERQTDRE 206
Query: 77 RERERDTDRKRSRKSPSPGRRNPE 100
R+R+R T +R R++ G R +
Sbjct: 207 RDRQRKTQTERQRETDREGERETD 230
Score = 31.6 bits (70), Expect = 3.5
Identities = 19/142 (13%), Positives = 52/142 (36%)
Query: 641 DELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEE 700
D +E + T K Q+ + + +E D + ++ E
Sbjct: 148 DREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRER 207
Query: 701 SDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTER 760
+ + ++ + R ++ D+ ++ +R +KE R++ +E + ER
Sbjct: 208 DRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKER 267
Query: 761 ERRSEKHRDQNSSGSNWRDPIT 782
+ + ++ + + W + I+
Sbjct: 268 KEKKKEEKRREDKKRKWGEGIS 289
Score = 31.2 bits (69), Expect = 4.6
Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 7/110 (6%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSR-RGRSYDSSMESRN----- 70
RE + + DR E+Q RDR+ + E R R R D E
Sbjct: 100 RERRRKEKETNRNRDR-EKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTE 158
Query: 71 RDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+DR+ +RE E + +R R R+ + + + + E T +++D
Sbjct: 159 KDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208
Score = 30.4 bits (67), Expect = 7.8
Identities = 20/107 (18%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSP---RDRDYFDYSRSDYEHSRRGRSYDSSMESRNR 71
++ N N + + +R E+E+ R+RD D + + R
Sbjct: 106 EKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQR 165
Query: 72 DREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
+ E RER+R+ ++++ R++ R +T + E ++K
Sbjct: 166 ETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRK 212
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 66.6 bits (161), Expect = 1e-10
Identities = 44/186 (23%), Positives = 89/186 (47%), Gaps = 20/186 (10%)
Query: 722 HGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPI 781
H T ++ +D+ ++ DR +++R +E ++ +ER+R+ ++ R++ R+
Sbjct: 9 HTHTETETMDRQRERRRETDR-ERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
Query: 782 TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIK 841
T ++ ER DRD++ + E K+R R++ ++ E+ + +
Sbjct: 68 TDREGERQRERER--------DRDRQRETERERD-----KERETDRHTETDRERQKQKER 114
Query: 842 DSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWE------KSSRYSEQSRESKKN 895
+ E R ++R K KEM R+ R + + AER E R+ E+ RE K+
Sbjct: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
Query: 896 QDRRRE 901
++R+RE
Sbjct: 175 RERKRE 180
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/229 (16%), Positives = 96/229 (41%), Gaps = 18/229 (7%)
Query: 669 SSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSK 728
S + + +E+++ D + + +S + HS R++ + R +
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
Query: 729 EVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDK 788
E +K + R+++ R E ++ER +++H + +D+
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTE----------------TDR 106
Query: 789 DVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRR 848
+ ++ DR++E ++ + ++ ER +E E+ T R + +E+ R
Sbjct: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQ-AERERETGRERKTED-RH 164
Query: 849 KDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
++R + ++ R+ + +R+ + R ++ R ++ RES++ +D
Sbjct: 165 RERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 45.1 bits (105), Expect = 3e-04
Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 12/122 (9%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSME---SRNRD 72
+ E +++ + + + E + + R+RD S+++ HS R R D R+R+
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
Query: 73 REKR------RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLL 126
REK+ R+RER+ DR R R++ R + T + D K+K+ E++ +
Sbjct: 64 REKQTDREGERQRERERDRDRQRETE---RERDKERETDRHTETDRERQKQKEREMERVR 120
Query: 127 TR 128
R
Sbjct: 121 DR 122
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/82 (29%), Positives = 37/82 (45%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
RE + + E + E + + R+R D R +R R + R R +
Sbjct: 132 RERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDME 191
Query: 77 RERERDTDRKRSRKSPSPGRRN 98
RER+R+TDRKR R+ S R+
Sbjct: 192 RERQRETDRKRDRQRESERERD 213
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 27 SSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRE----RERD 82
S E R+ E DR +D E R R+ +S E R+ +R+++R+ RERD
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRE---RDRAKESKTEDRHSERDRQRDRERNRERD 59
Query: 83 TDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
DR+R +++ G R E + + E K+++
Sbjct: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERE 97
Score = 40.8 bits (94), Expect = 0.006
Identities = 22/105 (20%), Positives = 46/105 (43%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
RE +R + + E + ++R+ ++ +D E ++ + R R+++K
Sbjct: 70 REGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKE 129
Query: 77 RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
RER TDR+ R+ R ET + + + +++K E
Sbjct: 130 MGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRE 174
Score = 40.4 bits (93), Expect = 0.008
Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 15/108 (13%)
Query: 803 DRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHS 862
DR +E + + + K+ + E R+S + ++ D E R +DR + +E
Sbjct: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQR------DRERNRERDRDREREKQTDRE 71
Query: 863 GSRS-----DEDRYQNGAERRWEK---SSRYSEQSRESKKNQDRRREK 902
G R D DR Q ER +K + R++E RE +K ++R E+
Sbjct: 72 GERQRERERDRDR-QRETERERDKERETDRHTETDRERQKQKEREMER 118
Score = 38.1 bits (87), Expect = 0.037
Identities = 31/180 (17%), Positives = 61/180 (33%), Gaps = 1/180 (0%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
A++ E S + E D +D E E + +
Sbjct: 34 AKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERD 93
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
R+ +E K + R ++ +Q+ +E +T+RE E+ R
Sbjct: 94 KERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERE 153
Query: 776 NWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLE-NKHGDPKKKRGERRNSFSENE 834
R+ T+ + + R +++E H D+E + + +KR +R S E +
Sbjct: 154 TGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 37.4 bits (85), Expect = 0.064
Identities = 26/103 (25%), Positives = 42/103 (40%), Gaps = 7/103 (6%)
Query: 25 RNSSPEDRYEEQERS-------PRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRR 77
+ S EDR+ E++R RDRD ++D E R+ R +RE+ +
Sbjct: 35 KESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDK 94
Query: 78 ERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
ERE D + R+ R E + Q E +++ D
Sbjct: 95 ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
Score = 35.0 bits (79), Expect = 0.32
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 1/108 (0%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRG-RSYDSSMESRNRDREK 75
RE +R E +++ R+ +D E R+ R ++ E + DR +
Sbjct: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR 165
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELD 123
RERER +R+R R++ R Q + + ++ + E D
Sbjct: 166 ERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 32.7 bits (73), Expect = 1.6
Identities = 16/68 (23%), Positives = 31/68 (45%)
Query: 54 EHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEP 113
E GR + E+ +R RE+RRE +R+ DR + K+ + + +D
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 114 ATKKKKDE 121
++K+ +
Sbjct: 62 REREKQTD 69
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 66.6 bits (161), Expect = 1e-10
Identities = 49/138 (35%), Positives = 74/138 (53%), Gaps = 4/138 (2%)
Query: 664 NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHG 723
+ SS S+SSS+ SSS S SS S S SS SSS S S DSSS +S SS S + R +GH
Sbjct: 582 SSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHN 641
Query: 724 KTRS--KEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPI 781
+ R + VD+ R+ +R K + ++T+ +++ S R ++ S S+ R
Sbjct: 642 RDRKHRRSVDRKRRDTSGLERSHKSSK-GGSSRDTKGSKDKNSRSDRKRSISESS-RSGK 699
Query: 782 TKYTSDKDVPSERNNYSR 799
S++D S+R + R
Sbjct: 700 RSSRSERDRKSDRKDKRR 717
Score = 61.2 bits (147), Expect = 4e-09
Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 3/152 (1%)
Query: 656 AQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
A+ + S SSSSS+SSS+ S S S S S SS SSS S +S SS S+S+
Sbjct: 566 ARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSST 625
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERR-QEHGHQETRTERERRSEKHRDQNSSG 774
+ ++R + ++ +++++ DRK+++ E H+ ++ R ++ +D+NS
Sbjct: 626 SSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRS 685
Query: 775 SNWRDPITKYTSDKDVPSERNNYSRVANDRDQ 806
R S K S R+ R ++ +D+
Sbjct: 686 DRKRSISESSRSGK--RSSRSERDRKSDRKDK 715
Score = 58.5 bits (140), Expect = 3e-08
Identities = 54/194 (27%), Positives = 79/194 (40%), Gaps = 45/194 (23%)
Query: 663 QNKSSPSSSSSASSSSESDSSDSDSDS-SDSSSESSSEESDSSSISSHSSASANDVRKKG 721
+NK+S S S S+SSSS S SS + S S S SSS SSS S SSS SS S +S+ D
Sbjct: 567 RNKTSKSRSRSSSSSS-SSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRD----- 620
Query: 722 HGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPI 781
+ + + R + G R + RRS + +++SG
Sbjct: 621 --------------SSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKS 666
Query: 782 TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIK 841
+K S +D ++ K R +R+ S SE+ + R
Sbjct: 667 SKGGSSRDTKGSKD------------------------KNSRSDRKRSISESSRSGKRSS 702
Query: 842 DSENFRRKDRSKSK 855
SE R+ DR +
Sbjct: 703 RSERDRKSDRKDKR 716
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/168 (20%), Positives = 65/168 (38%), Gaps = 3/168 (1%)
Query: 711 SASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQ 770
S S R + G+ R+K R+ ++ G + RS
Sbjct: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
Query: 771 NSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSF 830
++SGS+ RD + +S + R+ ++RD++ ++ K D ++S
Sbjct: 612 STSGSSSRDSSSSTSSSSE---SRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSK 668
Query: 831 SENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERR 878
+ + T KD + + RS S+ SRS+ DR + ++R
Sbjct: 669 GGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKR 716
Score = 37.7 bits (86), Expect = 0.049
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 13 GHDR-RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNR 71
GH+R R++ S R E +S + D S ++SR R S SR+
Sbjct: 639 GHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSG 698
Query: 72 DREKRRERERDTDRKRSRK 90
R R ER+R +DRK R+
Sbjct: 699 KRSSRSERDRKSDRKDKRR 717
Score = 36.2 bits (82), Expect = 0.14
Identities = 48/285 (16%), Positives = 99/285 (34%), Gaps = 43/285 (15%)
Query: 651 PKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSS----- 705
P++ +PD E SP + ++ E +S + + S+ E ++ S
Sbjct: 427 PEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQL 486
Query: 706 -------ISSHSSASANDV------------RKKGHGKTRSKEVDKLIRNQQTNDRKQKE 746
+ S + D+ +++GH K+ + + + + +
Sbjct: 487 QSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFP--VESVKLTEVPVEP 544
Query: 747 RRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQ 806
H +++T+ RS +S S R + +S S + S + +
Sbjct: 545 VLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSR 604
Query: 807 EMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS 866
+ G + +S SE+ R + R + +RKH S
Sbjct: 605 SSSSSSSSTSGSSSRDSSSSTSSSSES-------------RSRSRGRGHNRDRKHRRSVD 651
Query: 867 DEDRYQNGAERRWEKS----SRYSEQSRESKKNQDRRREKSPAKQ 907
+ R +G ER + S SR ++ S++ DR+R S + +
Sbjct: 652 RKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSR 696
Score = 32.0 bits (71), Expect = 2.7
Identities = 28/127 (22%), Positives = 48/127 (37%), Gaps = 6/127 (4%)
Query: 788 KDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFR 847
KD P E + V + +H + ++K + RG RN S++ + S +
Sbjct: 528 KDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSS 587
Query: 848 RKDRS-KSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKK-----NQDRRRE 901
S S S S S +G+ R SS S S+ N+DR+
Sbjct: 588 TSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHR 647
Query: 902 KSPAKQK 908
+S +++
Sbjct: 648 RSVDRKR 654
Score = 30.8 bits (68), Expect = 6.0
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 9/67 (13%)
Query: 393 ENEEKYKAIKKEILDEGDTDSNTDQ--DAGSSEEDE-------EEEEEEGEEDEEGQKVT 443
E EE A ++E L+E N + +AG EE E E+E+E EE ++ +V
Sbjct: 306 EQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVK 365
Query: 444 IHDKTEI 450
+ ++TE+
Sbjct: 366 MEEETEV 372
Score = 30.8 bits (68), Expect = 6.0
Identities = 32/123 (26%), Positives = 48/123 (39%), Gaps = 7/123 (5%)
Query: 6 AQIKPSSGHDRRENLNSYQRNS-SPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDS 64
A+ K S R + +S +S S S R S S S R S +
Sbjct: 566 ARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSST 625
Query: 65 SMESRNRDREKRRERERDTDRKRS----RKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
S S +R R + R RD +RS R+ S R+ ++S + S++D +K K
Sbjct: 626 SSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSS--KGGSSRDTKGSKDKNS 683
Query: 121 ELD 123
D
Sbjct: 684 RSD 686
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 64.7 bits (156), Expect = 4e-10
Identities = 46/197 (23%), Positives = 85/197 (43%), Gaps = 20/197 (10%)
Query: 716 DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETR-----TERERRSEKHRDQ 770
+ RK+G + S+ + ++ ++KER++E G +E + ERER+ + +
Sbjct: 46 ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE 105
Query: 771 NSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSF 830
N G K K ER S+ +R E K +++R ER
Sbjct: 106 NKEGEE------KEKRKKKEKKERGRTSKEGKER--------ERKEERKREERKERERKK 151
Query: 831 SENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSR 890
E EK R + + R++ K +E K R +R + ++ E+ R E+ +
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER-RERKK 210
Query: 891 ESKKNQDRRREKSPAKQ 907
E KK ++R++E+ +Q
Sbjct: 211 ERKKKEERKKERQKDRQ 227
Score = 59.7 bits (143), Expect = 1e-08
Identities = 37/183 (20%), Positives = 86/183 (46%), Gaps = 10/183 (5%)
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW 777
R+K + R K+ K R ++ +RK++ R +E+ E + +R+++ +K R + S
Sbjct: 73 REKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 778 RDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHT 837
R+ ++ ER R +R++E K +K+ GE+ E E+
Sbjct: 133 RE-----RKEERKREERKERERKKEEREKERERKERKKR--ERKQVGEKEEERKEKERKE 185
Query: 838 HRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
+ ++ RK+R K +E + + + + + ER+ ++ + + E+ R ++ ++
Sbjct: 186 RKKRERN---RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Query: 898 RRR 900
R++
Sbjct: 243 RKK 245
Score = 57.4 bits (137), Expect = 6e-08
Identities = 41/192 (21%), Positives = 83/192 (43%), Gaps = 32/192 (16%)
Query: 735 RNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSER 794
R ++ RK+ ++ +E ++ R ERE+R + + + K+ ER
Sbjct: 41 REREIETRKEGKKERESERKKERREREKRKREREKERK----------RERGKKEKKGER 90
Query: 795 NNYSRVANDRDQEMHIDLENKHGDPKKKR-----------------GERRNSFSENEKHT 837
R R +E ENK G+ K+KR ER+ E+
Sbjct: 91 KKEERERKKRRREK----ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
Query: 838 HRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAER-RWEKSSRYSEQSRESKKNQ 896
K E + ++R + K+ RK G + +E + + ER + E++ + ++ RE K+ +
Sbjct: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206
Query: 897 DRRREKSPAKQK 908
+R++E+ +++
Sbjct: 207 ERKKERKKKEER 218
Score = 53.9 bits (128), Expect = 7e-07
Identities = 48/211 (22%), Positives = 82/211 (38%), Gaps = 28/211 (13%)
Query: 690 SDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQ 749
S+ E E KKG K +E K R ++ + ++KE+R+
Sbjct: 57 SERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116
Query: 750 EHGHQET-RT-----ERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVAND 803
+ +E RT ERER+ E+ R++ ++ K ER R +
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK---------ERERKERKKRE 167
Query: 804 RDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSG 863
R Q + E K + K+++ RN E+ R + R+K+R K +E ++
Sbjct: 168 RKQVGEKEEERKEKERKERKKRERN---RKERKKERERKERRERKKERKKKEERKKER-- 222
Query: 864 SRSDEDRYQNGAERRWEKSSRYSEQSRESKK 894
+DR N W + R + +E KK
Sbjct: 223 ---QKDRQTN-----WREKERGKRERKERKK 245
Score = 46.6 bits (109), Expect = 1e-04
Identities = 41/183 (22%), Positives = 69/183 (37%), Gaps = 19/183 (10%)
Query: 679 ESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQ 738
E + + E + + KK G+T SKE + R ++
Sbjct: 80 ERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRT-SKEGKERERKEE 138
Query: 739 TNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYS 798
++KER E +E ERER+ K R++ G + K ++ ERN
Sbjct: 139 RKREERKER--ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK-KRERNRKE 195
Query: 799 RVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSE-NFRRKDRSKSKEM 857
R K + K++R ++ + E+ R KD + N+R K+R K +
Sbjct: 196 R--------------KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
Query: 858 NRK 860
RK
Sbjct: 242 ERK 244
Score = 41.2 bits (95), Expect = 0.004
Identities = 23/112 (20%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K G ++E +R E++ E++ + ++ + R+ E R R + E
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 69 RNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
R K+ ERE++ +RK +K R + + + E +KK++
Sbjct: 144 RKERERKKEEREKERERKERKK-----RERKQVGEKEEERKEKERKERKKRE 190
Score = 40.0 bits (92), Expect = 0.010
Identities = 25/107 (23%), Positives = 48/107 (44%), Gaps = 2/107 (1%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRD-RDYFDYSRSDYEHSRRGRSYDSSMESRNRDR 73
+ R+ +R E+R +E+ER R R+ + E + R E ++R
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 74 EKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+K RER+ +RK+ RK R+ Q++ + E +++K+
Sbjct: 197 KKERERKERRERKKERKKKEE-RKKERQKDRQTNWREKERGKRERKE 242
Score = 38.5 bits (88), Expect = 0.029
Identities = 23/106 (21%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYF---DYSRSDYEHSRRGRSYDSSMESRNRD 72
R E ++ E E +ER R+R + R + E R + + + + R ++
Sbjct: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER-KKRERNRKERKKE 199
Query: 73 REKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
RE++ RER +RK+ + +++ +T+ + + E +KK
Sbjct: 200 RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 38.1 bits (87), Expect = 0.037
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 9/103 (8%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFD------YSRSDYEHSRRGRSYDSSMESRNRDREKRR 77
++ E + EE+ER R R+ + R E RGR +S E + R+R++ R
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGR---TSKEGKERERKEER 139
Query: 78 ERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+RE +R+R ++ R E + ++ +K+K+
Sbjct: 140 KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182
Score = 35.0 bits (79), Expect = 0.32
Identities = 19/85 (22%), Positives = 33/85 (38%)
Query: 35 EQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSP 94
+ E R+R+ E + E R R+REK R+RER K+ +
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 95 GRRNPETSVTQSSSAQDEPATKKKK 119
R ++ +++ KKK+
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKE 119
Score = 33.9 bits (76), Expect = 0.71
Identities = 23/136 (16%), Positives = 50/136 (36%), Gaps = 7/136 (5%)
Query: 644 REHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDS 703
+E+ + K +K E+ ++S + + E E +
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKER 163
Query: 704 SSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERR 763
+ RK+ K R K ++ +RK++ R+ +E + + ER+
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK----KERKKKEERK 219
Query: 764 SEKHRDQNSSGSNWRD 779
E+ +D+ +NWR+
Sbjct: 220 KERQKDRQ---TNWRE 232
Score = 33.1 bits (74), Expect = 1.2
Identities = 18/88 (20%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 823 RGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDE--DRYQNGAERRWE 880
+ E R E E K+ E+ R+K+R + ++ R+ R E + + G ++ E
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 881 KSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ + + +E+K+ +++ + K K++
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKE 122
Score = 32.7 bits (73), Expect = 1.6
Identities = 25/117 (21%), Positives = 46/117 (39%), Gaps = 11/117 (9%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE- 74
RRE N + E++ER ++ + R + + + E R ++RE
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
Query: 75 ---KRRER----ERDTDRK---RSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
K+RER E++ +RK R + R + ++ +KKK+E
Sbjct: 161 KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEE 217
Score = 32.3 bits (72), Expect = 2.1
Identities = 18/81 (22%), Positives = 34/81 (41%)
Query: 41 RDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPE 100
R+R+ +R + + R E R RE+ +ER+R+ +K + R +
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 101 TSVTQSSSAQDEPATKKKKDE 121
+ + + E K+KK E
Sbjct: 99 KRRREKENKEGEEKEKRKKKE 119
Score = 32.3 bits (72), Expect = 2.1
Identities = 19/101 (18%), Positives = 44/101 (43%), Gaps = 4/101 (3%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDT 83
+R S + E+E+ R+R+ + R + ++G E + R REK + +
Sbjct: 54 ERESERKKERREREKRKREREK-ERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 84 DRKRSRKSPSPGR---RNPETSVTQSSSAQDEPATKKKKDE 121
++++ ++ GR E + ++ ++KK+E
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Score = 32.0 bits (71), Expect = 2.7
Identities = 18/97 (18%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 25 RNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTD 84
R ++R E+++ R+R+ R RG+ + K+R RE++ +
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE-N 106
Query: 85 RKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
++ K + E T + E ++K++E
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Score = 32.0 bits (71), Expect = 2.7
Identities = 16/75 (21%), Positives = 35/75 (46%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
+RE +R +++ E+++ R+R + + E + + + R R ++
Sbjct: 70 KREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE 129
Query: 76 RRERERDTDRKRSRK 90
+ERER +RKR +
Sbjct: 130 GKERERKEERKREER 144
Score = 30.4 bits (67), Expect = 7.8
Identities = 17/49 (34%), Positives = 22/49 (44%)
Query: 393 ENEEKYKAIKKEILDEGDTDSNTDQDAGSSEEDEEEEEEEGEEDEEGQK 441
E EEK K KKE + G T + E EE +E + EE +K
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 64.7 bits (156), Expect = 4e-10
Identities = 59/236 (25%), Positives = 99/236 (41%), Gaps = 27/236 (11%)
Query: 674 ASSSSESDSSDSDSDSSD-SSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDK 732
A+S +E D + S D + SE S S S H + R + + R ++ D
Sbjct: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYS-----RSRSRSRERKRKSDN 56
Query: 733 LIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPS 792
R ++ R ++ RR E + ++ ++ +SE+H D+ S R
Sbjct: 57 EGRKHRSRSRSKEGRRHE---SKDKSSKKHKSEEHNDKEHSSDKGR-------------- 99
Query: 793 ERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRS 852
ER N S DR + + + ERR+ E+ R + E R+K RS
Sbjct: 100 ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE--RKKSRS 157
Query: 853 KSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+S+E RK S SRS E + + + R R+ +SR +++ R R+K K +
Sbjct: 158 RSRE--RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPR 211
Score = 62.0 bits (149), Expect = 2e-09
Identities = 61/259 (23%), Positives = 100/259 (38%), Gaps = 30/259 (11%)
Query: 655 VAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASA 714
V+ P ++ S S S S +SD+ S S E ES S H S
Sbjct: 29 VSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEH 88
Query: 715 NDVRKKGHGKTRSKEVDKLIRNQQTNDR-KQKERRQEHG--HQETRTERERRSEKHRDQN 771
ND K H + +E +L ++ DR K+KER+ G H +R+ R + R++
Sbjct: 89 ND---KEHSSDKGRE--RLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERK 143
Query: 772 SSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFS 831
S S R+ + R+ + + R +E +K+R R+
Sbjct: 144 KSRSRSRE--------RKKSRSRSRERKKSRSRSRE------------RKRRIRSRSRSR 183
Query: 832 ENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGS--RSDEDRYQNGAERRWEKSSRYSEQS 889
+H R + R +DR K E R+ S S R+ G + + +
Sbjct: 184 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL 243
Query: 890 RESKKNQDRRREKSPAKQK 908
+KK Q++R ++ KQK
Sbjct: 244 ERAKKLQEQREKEMVEKQK 262
Score = 44.3 bits (103), Expect = 5e-04
Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 2 KSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQER-SPRDRDYFDYSRSDYEHSRRGR 60
KS K S RE LNS + EDR++ +ER S R R + + H R R
Sbjct: 84 KSEEHNDKEHSSDKGRERLNSSENG---EDRHKRKERKSSRGRSHSRSRSRERRHRSRSR 140
Query: 61 SYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRR 97
+SR+R RE+++ R R +RK+SR +R
Sbjct: 141 E---RKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
Score = 37.4 bits (85), Expect = 0.064
Identities = 45/189 (23%), Positives = 70/189 (37%), Gaps = 34/189 (17%)
Query: 14 HDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDR 73
H R + R+ S E R + + RS + SR + R R + SR+R R
Sbjct: 125 HSRSRSRERRHRSRSRE-RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
Query: 74 EKRRERERDTDRKRSRK---------------------SPSPGR-RNPETSVTQSSSAQD 111
+ R R R R RSR SP P R RN ++ + +
Sbjct: 184 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL 243
Query: 112 EPATK-----------KKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWE 160
E A K K+K + TGG+ + A L Q+T + ++A Q + +
Sbjct: 244 ERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQ 303
Query: 161 ALKKSINGL 169
A + G+
Sbjct: 304 AKALAETGI 312
Score = 35.4 bits (80), Expect = 0.24
Identities = 38/117 (32%), Positives = 49/117 (41%), Gaps = 9/117 (7%)
Query: 14 HDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDR 73
H R+E +S R+ S E + RS SRS R RS + +SR+R R
Sbjct: 112 HKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK-KSRSRSR 170
Query: 74 E-KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRT 129
E KRR R R R R R R S T+S S +D +K L+RT
Sbjct: 171 ERKRRIRSRSRSRSRHR------HRTRSRSRTRSRS-RDRKKRIEKPRRFSRSLSRT 220
Score = 32.7 bits (73), Expect = 1.6
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 32 RYEEQERSPRDRDYFDYSRSDYEHSR-RGRSYDSSMESRNRDREKRRERERDTDRKRSRK 90
R+E +++S + +++ D EHS +GR +S E+ DR KR+ER+ R SR
Sbjct: 72 RHESKDKSSKKHKSEEHN--DKEHSSDKGRERLNSSEN-GEDRHKRKERKSSRGRSHSR- 127
Query: 91 SPSPGRRNPETSVTQSSSAQDEPATKKKK 119
S S RR+ S + S KK +
Sbjct: 128 SRSRERRHRSRSRERKKSRSRSRERKKSR 156
Score = 32.3 bits (72), Expect = 2.1
Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 11/85 (12%)
Query: 37 ERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGR 96
E++ DRD +S+ S R + S SR+R RE++R+ + + + RSR GR
Sbjct: 14 EKTSPDRDK-KKEQSEVSVSPRASKHHYS-RSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
Query: 97 RNPETSVTQSSSAQDEPATKKKKDE 121
R+ ++D+ + K K +E
Sbjct: 72 RH---------ESKDKSSKKHKSEE 87
Score = 30.8 bits (68), Expect = 6.0
Identities = 25/126 (19%), Positives = 48/126 (38%), Gaps = 3/126 (2%)
Query: 648 KNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSIS 707
K++ K + D E + ++S + E + SS S S S + S
Sbjct: 78 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137
Query: 708 SHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKER---RQEHGHQETRTERERRS 764
+ R + K+RS+ ++ ++ +RK++ R R H+ R R
Sbjct: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 197
Query: 765 EKHRDQ 770
+ RD+
Sbjct: 198 SRSRDR 203
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 63.5 bits (153), Expect = 8e-10
Identities = 48/195 (24%), Positives = 94/195 (48%), Gaps = 24/195 (12%)
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW 777
R++ K R +E D+ I ++ DR++K R+ ++ +RER ++ R+ +
Sbjct: 68 RQRKRAKERHREKDREI--EKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125
Query: 778 RDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHT 837
R+ +KD ER + D+D+E+ + K D +++ GE T
Sbjct: 126 RERQRDRKREKD--RERQRQREIGIDKDREIETE---KDRDREREMGE-----------T 169
Query: 838 HRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSE----QSRESK 893
R +D E R+K R ++ +R+ R EDR ++ ++ + RY E + R+ +
Sbjct: 170 ERYRDRERERQKQRETRRDRDRER--QREKEDRERDRDRQKEREKDRYRERETGRDRDKE 227
Query: 894 KNQDRRREKSPAKQK 908
++++R+REK +QK
Sbjct: 228 RDRERQREKDRDRQK 242
Score = 48.9 bits (115), Expect = 2e-05
Identities = 31/143 (21%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW 777
R++ + R E ++ ++ DRK+++ R+ +E +++R E +D++
Sbjct: 108 RERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE-- 165
Query: 778 RDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHT 837
+ + +D ER DRD+E + E++ D +++ ++ + E E
Sbjct: 166 ---MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
Query: 838 HRIK--DSENFRRKDRSKSKEMN 858
R K D E R KDR + K ++
Sbjct: 223 DRDKERDRERQREKDRDRQKAID 245
Score = 41.2 bits (95), Expect = 0.004
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDRE 74
DR + DR ++E+ R+RD D + R Y R+RD+E
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERD------RDRQKEREKDRYRERETGRDRDKE 227
Query: 75 KRRERERDTDRKRSRKSPS-PGR 96
+ RER+R+ DR R + PGR
Sbjct: 228 RDRERQREKDRDRQKAIDCVPGR 250
Score = 40.4 bits (93), Expect = 0.008
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Query: 35 EQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSP 94
E+ER R+R+ R R R D +E ++RDR+++R+RER R R RK
Sbjct: 59 ERERQ-RERE-----RQRKRAKERHREKDREIE-KDRDRQRKRDRERQRWRDRDRKRERW 111
Query: 95 GRRNPETSVTQSSSAQDEPATKKKKD 120
G R+ ET + + + K++KD
Sbjct: 112 GDRDRETETERQEERERQRDRKREKD 137
Score = 39.3 bits (90), Expect = 0.017
Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 5/97 (5%)
Query: 7 QIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSM 66
+I+ DR + +R E ++Q + RDRD E R R D
Sbjct: 153 EIETEKDRDREREMGETERYRDRERERQKQRETRRDRD----RERQREKEDRERDRDRQK 208
Query: 67 ESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSV 103
E R +DR + RE RD D++R R+ R+ + ++
Sbjct: 209 E-REKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
Score = 37.0 bits (84), Expect = 0.083
Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 9/94 (9%)
Query: 6 AQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERS---------PRDRDYFDYSRSDYEHS 56
+++ P+ +R ++ ++R+ E++R RDR+ + D +
Sbjct: 50 SRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE 109
Query: 57 RRGRSYDSSMESRNRDREKRRERERDTDRKRSRK 90
R G + R +RE++R+R+R+ DR+R R+
Sbjct: 110 RWGDRDRETETERQEERERQRDRKREKDRERQRQ 143
Score = 37.0 bits (84), Expect = 0.083
Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRR---GRSYDSSMES-RNR 71
+RE R + E R EE+ER RDR D E R+ G D +E+ ++R
Sbjct: 107 KRERWGDRDRETETE-RQEERERQ-RDRK----REKDRERQRQREIGIDKDREIETEKDR 160
Query: 72 DREKRR-ERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDELDPLLTRTG 130
DRE+ E ER DR+R R+ RR+ + + ++ ++K+ E D R
Sbjct: 161 DREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET 220
Query: 131 G 131
G
Sbjct: 221 G 221
Score = 36.6 bits (83), Expect = 0.11
Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 6/129 (4%)
Query: 776 NWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEK 835
+WR + D+DV R + A R++E + E + K++ E+ E ++
Sbjct: 30 SWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREI-EKDR 88
Query: 836 HTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAER---RWEKSSRYSEQSRES 892
R +D E R +DR + +E R R E Q ER R + R ++ RE
Sbjct: 89 DRQRKRDRERQRWRDRDRKRE--RWGDRDRETETERQEERERQRDRKREKDRERQRQREI 146
Query: 893 KKNQDRRRE 901
++DR E
Sbjct: 147 GIDKDREIE 155
Score = 36.6 bits (83), Expect = 0.11
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Query: 15 DRRENLNSYQRNSSPEDRYEEQERS-PRDRDY-FDYSRSDYEHSRRGRSYDSSMESRNRD 72
DR + DR E++R R R+ D R R R + R RD
Sbjct: 115 DRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD 174
Query: 73 REKRRERERDTDRKRSRK 90
RE+ R+++R+T R R R+
Sbjct: 175 RERERQKQRETRRDRDRE 192
Score = 31.2 bits (69), Expect = 4.6
Identities = 18/88 (20%), Positives = 38/88 (43%)
Query: 34 EEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPS 93
E Q RDR + D E + R R++++ R+R+R+ + R+ +
Sbjct: 97 ERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIET 156
Query: 94 PGRRNPETSVTQSSSAQDEPATKKKKDE 121
R+ E + ++ +D ++K+ E
Sbjct: 157 EKDRDREREMGETERYRDRERERQKQRE 184
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 62.8 bits (151), Expect = 1e-09
Identities = 61/258 (23%), Positives = 105/258 (40%), Gaps = 18/258 (6%)
Query: 662 EQNKSSPSSSSSASSSSESDSSD-SDSDSSDSSSESSSEESDSSSISSHSSASANDVRKK 720
E+N S S+ S S S+SS S S SS S S S S S SSHS + + R
Sbjct: 668 EKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRS- 726
Query: 721 GHGKTRSKEVDKLIRNQQ------TNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSG 774
H + + + + R+ + R+ K R + G + + + ++ S + +S
Sbjct: 727 -HSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKY 785
Query: 775 SNWRDP---ITKYTS-----DKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGER 826
RD + KY+ D SE+++ + +++E +E H +K RGE
Sbjct: 786 VKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEE 845
Query: 827 RNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSD-EDRYQNGAERRWEKSSRY 885
++ H+ + EN R+ SK + ++GS+ D E + + + S
Sbjct: 846 KSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHP 905
Query: 886 SEQSRESKKNQDRRREKS 903
S E + D E S
Sbjct: 906 SSDKEEGEATSDSESEVS 923
Score = 51.6 bits (122), Expect = 3e-06
Identities = 61/267 (22%), Positives = 102/267 (38%), Gaps = 32/267 (11%)
Query: 644 REHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDS 703
R H K T K + D+E +KS S+ SS SS S S SS SS+ +SD
Sbjct: 449 RRH-KQTKKRRILIPSDIESSKS--STRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDK 505
Query: 704 SSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERR 763
SS + +S + R K H ++ S+ + + + H +R+ + R
Sbjct: 506 DVQSSLTHSSRDSYRSKSHSQSYSR-----------GSSRSRTASKSSSHSRSRS-KSRS 553
Query: 764 SEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLEN--------- 814
S K + + + R ++ + +K V +E + N+ + EN
Sbjct: 554 SSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDS 613
Query: 815 ------KHGD-PKKKRGERRNSFSENEKHTHRIKDSENFRR-KDRSKSKEMNRKHSGSRS 866
K G P K ER H I+ + + K+ S +++ S S
Sbjct: 614 PPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSES 673
Query: 867 DEDRYQNGAERRWEKSSRYSEQSRESK 893
D+ Y ++R E S R +S S+
Sbjct: 674 DQSTYSKYSDRSSESSPRSRSRSSRSR 700
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/307 (19%), Positives = 105/307 (34%), Gaps = 68/307 (22%)
Query: 639 LTDELREHLKNTPKVIVAQKPDVEQNKS-----------SPSSSSSASSSSESDSSDSDS 687
+T E + + ++ QKP V ++ +P S S S S + DSS++
Sbjct: 304 VTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPP 363
Query: 688 --------------------DSSDSSSESSSEESDSSSISSHSSA--------SANDVRK 719
D S+ S D S+S S + + R
Sbjct: 364 HWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARH 423
Query: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRD 779
GH K R KE K +++ K+K ++Q+H + +T++ R
Sbjct: 424 SGHHKKRRKE--KKVKH------KKKGKKQKHCRRHKQTKKRR----------------- 458
Query: 780 PITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHR 839
D+ S +++ R+ + D+E + KR ++ TH
Sbjct: 459 ----ILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHS 514
Query: 840 IKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRR 899
+DS + +S S+ +R + S+S R KS S+ +K +
Sbjct: 515 SRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQL 574
Query: 900 REKSPAK 906
E P K
Sbjct: 575 SENKPVK 581
Score = 49.7 bits (117), Expect = 1e-05
Identities = 68/285 (23%), Positives = 111/285 (38%), Gaps = 44/285 (15%)
Query: 658 KPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSE----ESDSSSISSHSSAS 713
K ++ +SS SSS S+ SS+ D S SD D S + SS + +S S S S SS S
Sbjct: 476 KSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRS 535
Query: 714 ANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSS 773
+ H ++RSK + ++ RK+ + + + ++E R +
Sbjct: 536 RTASKSSSHSRSRSKSRS----SSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQ 591
Query: 774 GSN-WRDPITKYT------SDKDVPSE--------RNNYSRVANDRDQEMHI-------D 811
N P+ SD PS + +Y R+ + + H+
Sbjct: 592 NENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYS 651
Query: 812 LEN--KHGDPKKKRGERRNSFSEN---EKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS 866
L N + G +NS S+ K++ R +S R S+S+ +R ++ SRS
Sbjct: 652 LANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRS 711
Query: 867 -----DEDRYQNGAERRWEKSSRYSEQSRESK----KNQDRRREK 902
R + K S +S+ SR S + D RR K
Sbjct: 712 LASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAK 756
Score = 45.4 bits (106), Expect = 2e-04
Identities = 50/227 (22%), Positives = 88/227 (38%), Gaps = 25/227 (11%)
Query: 639 LTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESS- 697
L+D LR K K K D E N + +S + S S + +SDS SE S
Sbjct: 865 LSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSE 924
Query: 698 ---SEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQ 754
+ + S ++ S N K +T + + + N + N + K ++ +HG +
Sbjct: 925 IHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENN--RGKPQKHKHGSK 982
Query: 755 ETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLEN 814
E + K + + + P K P E ++E ID +
Sbjct: 983 ENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFG--------EEEEEEIDDKQ 1034
Query: 815 KHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKH 861
+ K+K+ SEN + IKD N + ++S ++++ KH
Sbjct: 1035 VTQESKEKK------VSENNE---TIKD--NILKTEKSSEEDLSGKH 1070
Score = 39.3 bits (90), Expect = 0.017
Identities = 51/220 (23%), Positives = 84/220 (38%), Gaps = 48/220 (21%)
Query: 616 LPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSAS 675
+P P+ R I + G L DE+R+ + + ++P ++ SSS +
Sbjct: 1254 VPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTAR------LNRRP-----RNQESSSDEQT 1302
Query: 676 SSSESDSSDSDSDSSDSSSE------------SSSEESDSSSISSHSSASANDVRKKG-- 721
S + DS S S SE S S SS SS+ S S + R +G
Sbjct: 1303 PSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWY 1362
Query: 722 -HGKTRSKEVD-KLIRNQQTNDRKQKERRQEHGHQETRT-------------ERERRSEK 766
G+TRS+ + ++ +T+ R + H +R+ R +RS+
Sbjct: 1363 SRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDS 1422
Query: 767 H---RDQNSSGSNWRDPITKYTSDKDV-----PSERNNYS 798
+ R N + R + SD+ PSE + YS
Sbjct: 1423 YHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462
Score = 34.3 bits (77), Expect = 0.54
Identities = 40/130 (30%), Positives = 52/130 (40%), Gaps = 25/130 (19%)
Query: 4 SVAQIKP----SSGHDRRENLNSYQRNSSP-EDRYEEQERSPRDRDYFDYSRSDYEHSRR 58
S+A IK SS H R +N S Q S DR E SPR R SRS R
Sbjct: 651 SLANIKETGSSSSYHKREKNSESDQSTYSKYSDR--SSESSPRSRSRSSRSRSYSRSYTR 708
Query: 59 GRSYDS------SMESRNRDREKRRERER------------DTDRKRSRKSPSPGRRNPE 100
RS S S SR+ R K + + D R+ R+ S G++N
Sbjct: 709 SRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSV 768
Query: 101 TSVTQSSSAQ 110
+ SSS++
Sbjct: 769 SHKKHSSSSE 778
Score = 33.9 bits (76), Expect = 0.71
Identities = 62/264 (23%), Positives = 90/264 (34%), Gaps = 50/264 (18%)
Query: 677 SSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRN 736
S SDSS + S SS+SSSES E + S H K K R KE
Sbjct: 195 SEGSDSSSNSSSSSESSSESELEH-ERSRRRKHKRRP-----KVKRSKKRRKEA------ 242
Query: 737 QQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNN 796
+ + + K GH E E+RS S + P+ + VP R
Sbjct: 243 SSSEEPRNKHAMNPKGHSERSDTNEKRSV------DSSAKREKPVVRPEEIPPVPENRFL 296
Query: 797 YSR---VANDRDQEMHIDLE----------NKHGDPKKKRGERRNSFSENEKHTHRIKDS 843
R V + D+ +K G K RG R + D
Sbjct: 297 LRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDD 356
Query: 844 ENFRR----KDRSKSKEMNRKHSGSR-SDEDRYQNGAERRWEKSS------------RYS 886
++ K+ + R SG + S D+ + RW++ S YS
Sbjct: 357 DSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYS 416
Query: 887 EQS--RESKKNQDRRREKSPAKQK 908
+ S R S ++ RR+EK +K
Sbjct: 417 DLSTARHSGHHKKRRKEKKVKHKK 440
Score = 32.7 bits (73), Expect = 1.6
Identities = 29/135 (21%), Positives = 52/135 (38%), Gaps = 4/135 (2%)
Query: 2 KSSVAQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRS 61
KSS ++K S +R +S + S + + + ++ + SR Y +S
Sbjct: 469 KSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQS-SLTHSSRDSYRSKSHSQS 527
Query: 62 YDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
Y S SR+R K R R +SR S G R + + +++Q K +
Sbjct: 528 Y-SRGSSRSRTASKSSSHSRS--RSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEP 584
Query: 122 LDPLLTRTGGAYIPP 136
L + + + P
Sbjct: 585 LRATMAQNENVVVQP 599
Score = 31.2 bits (69), Expect = 4.6
Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 3/94 (3%)
Query: 815 KHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNG 874
+H KK+R + ++ T R+K S + R RS S H S+ D +
Sbjct: 450 RHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLS---SHHSSKRDWSKSDKD 506
Query: 875 AERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ SSR S +S+ ++ R +S K
Sbjct: 507 VQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASK 540
Score = 30.8 bits (68), Expect = 6.0
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 5/105 (4%)
Query: 804 RDQEMHIDLEN-KHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKE---MNR 859
R+QE D + D + R R+ K HR + + RS+S +R
Sbjct: 1292 RNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSR 1351
Query: 860 KHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSP 904
+S SRS Y G R S R + R S +++ R P
Sbjct: 1352 SYSRSRS-RGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDP 1395
Score = 30.4 bits (67), Expect = 7.8
Identities = 35/188 (18%), Positives = 74/188 (39%), Gaps = 20/188 (10%)
Query: 726 RSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSE---KHRDQNSSGSNWRDPIT 782
++ +++ RNQ+++ +Q R + + + +SE +HR ++ S S+ R
Sbjct: 1283 KTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSR 1342
Query: 783 KYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKD 842
TS S + SR R + + R S+ + +
Sbjct: 1343 SSTSSYRSRSYSRSRSRGWYSRGRT-------------RSRSSSYRSYKSHRTSSRSRSR 1389
Query: 843 SENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSR----ESKKNQDR 898
S ++ RS+S + +S SRS ++ + R +R S R +S+ ++
Sbjct: 1390 SSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSY 1449
Query: 899 RREKSPAK 906
+SP++
Sbjct: 1450 SHHRSPSE 1457
>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
sapiens]
Length = 558
Score = 62.4 bits (150), Expect = 2e-09
Identities = 60/277 (21%), Positives = 111/277 (40%), Gaps = 54/277 (19%)
Query: 679 ESDSSDSDSDSSDSSSESSSE-----------ESDSSSISSHSSA--SANDVRKKGHGKT 725
E+ +DSD D+ S+ + E E+ + H S S + ++GH
Sbjct: 242 ENPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTR 301
Query: 726 RSKEVDKLIRNQQTND--RKQKERRQEHGHQETRTER-ERRSEKHRDQNSSGSNWR---- 778
+ + R + + +QK+ R + H R R ER S +HR+ + S+W+
Sbjct: 302 HHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQ 361
Query: 779 -------------DPITKYTSDKDVPSER--------NNYSRVANDRDQEMHIDLENKHG 817
D + K D++ S+R N+ +R + ++E + +H
Sbjct: 362 EDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHM 421
Query: 818 DPKKKRGERRNSFSENEKHTHRIKDSE----------NFRRKDRSKSKEMNRKHSGSRSD 867
+K+R E + + + EK ++ SE N R KD+ +E + K D
Sbjct: 422 KVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKD 481
Query: 868 EDRYQ---NGAERRWEKSSRYSEQSRESKKNQDRRRE 901
++R Q + +E R +E+ +E K Q+R E
Sbjct: 482 KERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPE 518
Score = 56.6 bits (135), Expect = 1e-07
Identities = 59/264 (22%), Positives = 107/264 (40%), Gaps = 27/264 (10%)
Query: 653 VIVAQKPDVEQNKSSPSSSSSASSSS----------ESDSSDSDSDSSDSSSESSSEESD 702
V V + PD + + + SS+ + E+ +D S + S S SEE
Sbjct: 238 VKVEENPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERG 297
Query: 703 SSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTN--DRKQKERRQEHGHQETRTER 760
S+ H+ S +GH K + K R+Q+ + DR ++ R H H+E + R
Sbjct: 298 HST-RHHTKGSRTS---RGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREA-SHR 352
Query: 761 ERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPK 820
+ ++H ++ + RD + +R YS+ +RD++ +N P
Sbjct: 353 DSHWKRHEQEDKPRA--RDQRERSDRVWKREKDREKYSQREQERDRQ-----QNDQNRPS 405
Query: 821 KKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWE 880
+K GE+ E+H K+ K R + K S R+ + + + R +
Sbjct: 406 EK-GEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKD 464
Query: 881 K--SSRYSEQSRESKKNQDRRREK 902
K S + R K+++R +EK
Sbjct: 465 KFLDQERSNKMRNMAKDKERNQEK 488
Score = 43.5 bits (101), Expect = 9e-04
Identities = 28/123 (22%), Positives = 60/123 (48%), Gaps = 16/123 (13%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQ------------ERSPRDRDYFDYSRSDYEHS 56
+ S GH++RE+ + +++ E+ Y ++ E S RD + + + D +
Sbjct: 308 RTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRA 367
Query: 57 RRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATK 116
R R + R +DREK +RE++ DR+++ ++ R + + + S A++E
Sbjct: 368 RDQRERSDRVWKREKDREKYSQREQERDRQQNDQN----RPSEKGEKEEKSKAKEEHMKV 423
Query: 117 KKK 119
+K+
Sbjct: 424 RKE 426
Score = 40.0 bits (92), Expect = 0.010
Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDR-DYFDYSRSDYEHSR-RGRSYDSSMESRNRDR 73
R ++ Y + DR + + P ++ + + S++ EH + R Y+++ + RDR
Sbjct: 380 REKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENN--DKYRDR 437
Query: 74 EKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
EKR + ++R + RK SP R + + Q S + K K+
Sbjct: 438 EKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKE 483
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 59.7 bits (143), Expect = 1e-08
Identities = 48/212 (22%), Positives = 91/212 (42%), Gaps = 20/212 (9%)
Query: 705 SISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRS 764
S S S S+ ++ + R +E LI D+K+++RR +R R S
Sbjct: 207 SPSLKSDTSSKEIEE---AMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSS 263
Query: 765 EKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRG 824
+HR S ++ P R ++SR R + + K D +KKR
Sbjct: 264 SRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRS 323
Query: 825 E---------RRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSR------SDED 869
+ RR+ + E+ R + +K RS ++++R S R D+D
Sbjct: 324 KTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKD 383
Query: 870 RYQNGAERRWEKSSRYSEQSRESKKNQDRRRE 901
+ ++ ER E+S+ ++S++ +K+++R+ E
Sbjct: 384 KERSRDER--ERSTSKKKKSKDKEKDRERKSE 413
Score = 53.1 bits (126), Expect = 1e-06
Identities = 66/281 (23%), Positives = 104/281 (37%), Gaps = 40/281 (14%)
Query: 642 ELREHLKNTPK----VIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESS 697
E+ E +K + + A +PD ++ K S S S S + SS S S S
Sbjct: 218 EIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRS 277
Query: 698 SEESDSSSIS----------------SHSSASANDVRKKGHGKTRSKEVDKLIRNQQTND 741
+S S S S S++ D +K+ K RSK K + +
Sbjct: 278 HSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSR 337
Query: 742 RKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVA 801
+ERR+ TR+ ++ RS K + S K DK+
Sbjct: 338 SASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKE------------ 385
Query: 802 NDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKH 861
RD+ + K K+K ER++ ++ K R D E + D K K+ +K
Sbjct: 386 RSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEE-QGYDSEKEKKEEKKP 444
Query: 862 SGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREK 902
+ S + + E EK + + RESK N D E+
Sbjct: 445 IETGSPKTK-----ECSVEKGT--GDSLRESKVNGDDHHEE 478
Score = 47.4 bits (111), Expect = 6e-05
Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 17/123 (13%)
Query: 10 PSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESR 69
PSS RR S +R+ S + R + +SPR R +SR E RR RS + + +
Sbjct: 261 PSSSRHRRSRSRSRRRSHS-KSRSRRRSKSPRRRR--SHSR---ERGRRSRSTSKTRDKK 314
Query: 70 NRDREKRR-----------ERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
D+EK+R R R R+R R+ G R+P+ + P+ ++
Sbjct: 315 KEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH 374
Query: 119 KDE 121
K E
Sbjct: 375 KKE 377
Score = 46.2 bits (108), Expect = 1e-04
Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 818 DPKKKRGERRNSFSENEKHTHRIKDSENFRR-KDRSKSKEMNRKHSGSRSDEDRYQNGAE 876
+P KK +RR+S S + R S RR + RS+ + ++ S RS R +
Sbjct: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297
Query: 877 RRWEKSSRYSEQSRESKK-NQDRRREKSPAK 906
R + SR + ++R+ KK +++++R K+P K
Sbjct: 298 RERGRRSRSTSKTRDKKKEDKEKKRSKTPPK 328
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 20/101 (19%)
Query: 31 DRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRK 90
D+ EE+ R R R SRR R+ SS R+R R +RR + R+RS+
Sbjct: 240 DKKEEKRRHSRSRS----------RSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKS 289
Query: 91 -------SPSPGRRNPETSVTQSSSAQDEPATKKKKDELDP 124
S GRR+ TS T+ +D+ +KK+ + P
Sbjct: 290 PRRRRSHSRERGRRSRSTSKTRDKKKEDK---EKKRSKTPP 327
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 12/125 (9%)
Query: 11 SSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRN 70
S RR + + +R S +R + + RD + +SY ++ SR+
Sbjct: 279 SKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRS 338
Query: 71 RDREKRRERERDTDR---------KRSRKSPSPGRRNPETSV---TQSSSAQDEPATKKK 118
RE+RR R R R ++ +SPSP R E + S + E +T KK
Sbjct: 339 ASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKK 398
Query: 119 KDELD 123
K D
Sbjct: 399 KKSKD 403
Score = 36.6 bits (83), Expect = 0.11
Identities = 42/177 (23%), Positives = 67/177 (37%), Gaps = 19/177 (10%)
Query: 648 KNTPKVIVAQKPDVEQNKS-SPSSSSSASSSSESDSSDSDSDSSDSSSESSSEE------ 700
++T K +K D E+ +S +P S S + S S S + S S + S +
Sbjct: 305 RSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRK 364
Query: 701 -SDSSSISSHSSASANDVRKKGHG-----------KTRSKEVDKLIRNQQTNDRKQKERR 748
S S S H D K+ K++ KE D+ +++ D KQ R
Sbjct: 365 LSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRD 424
Query: 749 QEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRD 805
+ Q +E+E++ EK + S + K T D S+ N D D
Sbjct: 425 YDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMD 481
Score = 36.6 bits (83), Expect = 0.11
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 14/128 (10%)
Query: 3 SSVAQIKPSSGHDRRENLNSYQRN-SSPEDRYEEQERSPRDRDYFDYSRSDY--EHSRRG 59
S+ + + +S RR S R+ P + RSP R + + D E SR
Sbjct: 331 STARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDE 390
Query: 60 RSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
R +S + +++D+EK RER+ ++D+ + + Q + K+KK
Sbjct: 391 RERSTSKKKKSKDKEKDRERKSESDKDVK-----------QVTRDYDEEEQGYDSEKEKK 439
Query: 120 DELDPLLT 127
+E P+ T
Sbjct: 440 EEKKPIET 447
Score = 35.0 bits (79), Expect = 0.32
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 14 HDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDR 73
H R + + +R S + RS R SR + RR RS+ R+R
Sbjct: 248 HSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRST 307
Query: 74 EKRRERER-DTDRKRSR---KSPSPGRRNPETS 102
K R++++ D ++KRS+ KS S RR+ S
Sbjct: 308 SKTRDKKKEDKEKKRSKTPPKSYSTARRSRSAS 340
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 59.3 bits (142), Expect = 2e-08
Identities = 37/174 (21%), Positives = 84/174 (48%), Gaps = 8/174 (4%)
Query: 735 RNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSER 794
R ++ +R++++R +E + R ++E++ K R++ R K ++ ER
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR-EKER 94
Query: 795 NNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKS 854
+ R+++ E K KKK + R ++ + R K + RRK+R +
Sbjct: 95 RKRKKEKKKRERKQRGRRERK----KKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 855 KEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
KE ++ R + R + E++ E++ + ++ RE K+ ++R++E+ ++K
Sbjct: 151 KERGKR---ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Score = 56.6 bits (135), Expect = 1e-07
Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 9/190 (4%)
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW 777
+++ + R +E +K + ++ K+K +++E G + R +ER EK R +
Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER--EKQRKERREKER- 94
Query: 778 RDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHT 837
K +K + R + + + ENK ++KR +RR E+
Sbjct: 95 ----RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRR-ERKRKKRRKKKRRKERKR 149
Query: 838 HRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQD 897
+ + +RK R K +E +K +R + + + ERR K R E+ ++ ++ +D
Sbjct: 150 EKERGKRERKRKKR-KKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Query: 898 RRREKSPAKQ 907
R+ ++ Q
Sbjct: 209 RKTDRQTDSQ 218
Score = 48.9 bits (115), Expect = 2e-05
Identities = 33/160 (20%), Positives = 70/160 (43%), Gaps = 6/160 (3%)
Query: 755 ETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLEN 814
E + ER R ++ R++ R K K + R ++ ++ + E
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
Query: 815 KHGDPKKKRGER--RNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDE---- 868
+ +KK+ ER R +K + ++ EN +R++R + K +K R E
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154
Query: 869 DRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
R + +R+ E+ + E++R+ +K + R+E+ K++
Sbjct: 155 KRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Score = 47.4 bits (111), Expect = 6e-05
Identities = 35/143 (24%), Positives = 68/143 (47%), Gaps = 4/143 (2%)
Query: 718 RKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNW 777
R+K + R KE K + ++ +RKQ+ RR+ +E R ERER +++ R++
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE-RKERERENKQRRERKRKKRRK 140
Query: 778 RDPITKYTSDKDVPS-ERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKH 836
+ + +K+ ER R +R+++ + K +++R ERR E +K
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKR--ERNRKERKKERERKERRERKKERKKE 198
Query: 837 THRIKDSENFRRKDRSKSKEMNR 859
+ K+ + R+ DR ++ R
Sbjct: 199 RRKKKERKKDRKTDRQTDSQVFR 221
Score = 45.1 bits (105), Expect = 3e-04
Identities = 26/113 (23%), Positives = 47/113 (41%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K G ++ +R E + +E+E+ ++R + + E +R R E
Sbjct: 55 KRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRER 114
Query: 69 RNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
+ + K RERE R+R RK +R E + ++ K+KK+E
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Score = 40.8 bits (94), Expect = 0.006
Identities = 24/106 (22%), Positives = 46/106 (43%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
+RE +R + +E+ER + R + + R+ R + R R R+K
Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162
Query: 76 RRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
R++ ER+ R+R+RK R E + ++ K++K +
Sbjct: 163 RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Score = 39.3 bits (90), Expect = 0.017
Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K RE N +R + R +++ R R R+ R E R+ R + +
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREK---ERGKRERKRKKRKKEEREKK 171
Query: 69 RNRDR-EKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDE 112
R R+R E+++ERER R+R ++ R+ E + + Q +
Sbjct: 172 RERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTD 216
Score = 36.2 bits (82), Expect = 0.14
Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 32 RYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRER-ERDTDRKRSRK 90
R E+++ R+R+ R RG+ + R R +E+ R+R ER+ RK R+
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 91 SPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
R+ + + + E KK++ E
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKE 122
Score = 34.7 bits (78), Expect = 0.41
Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 9/98 (9%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDT 83
QR S + E+E+ R+R+ + +R R + + R+R K RER+R
Sbjct: 31 QRESERKKERREREKRKRERE---------KERKRERGKKEKKKRKKRERGKERERKRKE 81
Query: 84 DRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDE 121
K+ ++ RR + + Q +KKK E
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKE 119
Score = 34.7 bits (78), Expect = 0.41
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 6/86 (6%)
Query: 718 RKKGHGK-TRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSN 776
R+K GK R ++ K ++ +R +KER++E +E + RER+ E+ +++
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKE---RERKERRERKKERKKERRKKKER 205
Query: 777 WRDPITKYTSDKDV--PSERNNYSRV 800
+D T +D V P + ++RV
Sbjct: 206 KKDRKTDRQTDSQVFRPLRESAFNRV 231
Score = 33.5 bits (75), Expect = 0.92
Identities = 22/108 (20%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRD--- 72
R+E + E R ++E+ R+R R E ++ + E++ R
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERK----QRGRRERKKKKERKERERENKQRRERK 134
Query: 73 REKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
R+KRR+++R +RKR ++ R+ + + ++ ++KK+
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKE 182
Score = 31.6 bits (70), Expect = 3.5
Identities = 23/109 (21%), Positives = 42/109 (38%), Gaps = 5/109 (4%)
Query: 16 RRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREK 75
R+E +R E + E+++ R R + E + R + R + R K
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 76 RRERE-----RDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKK 119
R+RE R+ RK+ +K +R + + E +KK+
Sbjct: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Score = 30.4 bits (67), Expect = 7.8
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 8/81 (9%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDT 83
++ E+R +++ER+ ++R E R+ R + R ++K R+++R T
Sbjct: 160 RKKRKKEEREKKRERNRKER--------KKERERKERRERKKERKKERRKKKERKKDRKT 211
Query: 84 DRKRSRKSPSPGRRNPETSVT 104
DR+ + P R + VT
Sbjct: 212 DRQTDSQVFRPLRESAFNRVT 232
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 59.3 bits (142), Expect = 2e-08
Identities = 53/216 (24%), Positives = 92/216 (42%), Gaps = 29/216 (13%)
Query: 692 SSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEH 751
+S S S+E D+ ++ S + +G + + + + DRKQKE
Sbjct: 140 ASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR--------DRKQKEEL--- 188
Query: 752 GHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHID 811
+E R RE+ +K + + + G+ R+ + + P R +RD++
Sbjct: 189 --KEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRD---- 242
Query: 812 LENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS-DEDR 870
+KK ER+ SE K R++D + R +D+ K ++ R +G S D DR
Sbjct: 243 ------SERKKETERK---SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDR 293
Query: 871 YQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAK 906
+N + EK S S + SKK D + S A+
Sbjct: 294 EKNREHDKPEKKSASSGEM--SKKLSDGTFKDSKAE 327
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 22/194 (11%)
Query: 721 GHGKTRSKEVDKLI-----RNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
GH R+ E+ ++I ++D ++ E G + R RS++ ++N
Sbjct: 98 GHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREE 157
Query: 776 NWRDPITKYTSDK-DVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENE 834
R + K T D+ D + + SR DR Q+ + + K P++K ++ + EN
Sbjct: 158 ESR--VHKNTEDRGDAEIKERSTSR---DRKQKEELKEDRK---PREKDKDKEKA-KENG 208
Query: 835 KHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKK 894
+ HR + E R K R++ +K G+R + DR +ER+ E + R SE +E ++
Sbjct: 209 GNRHR--EGERERAKARARPDNERQKDRGNR-ERDR---DSERKKE-TERKSEGGKEKER 261
Query: 895 NQDRRREKSPAKQK 908
+DR RE+ K K
Sbjct: 262 LRDRDRERDRDKGK 275
Score = 40.8 bits (94), Expect = 0.006
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K + G+ RE + + D +++R R+RD + + E G +
Sbjct: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL-- 262
Query: 69 RNRDREKRRERERDTDRKRSRKSPS----PGRRNPETSVTQSSSAQDEPATKKKKD 120
R+RDRE+ R++ +D DR+R + +N E + SA +KK D
Sbjct: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSD 318
Score = 34.7 bits (78), Expect = 0.41
Identities = 46/228 (20%), Positives = 80/228 (35%), Gaps = 37/228 (16%)
Query: 641 DELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSS--DSDSDSSDSSSESSS 698
+E R H KNT + D E + S S + D + D D + +
Sbjct: 157 EESRVH-KNTE-----DRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGN 210
Query: 699 EESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRT 758
+ + + A ++ R+K G R++ + +K+ ER+ E G ++ R
Sbjct: 211 RHREGERERAKARARPDNERQKDRGNRE--------RDRDSERKKETERKSEGGKEKERL 262
Query: 759 ERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGD 818
R+R E+ RD+ D+D +N DR++ +H
Sbjct: 263 -RDRDRERDRDKG--------------KDRDRRRVKNGEHSWDLDREK------NREHDK 301
Query: 819 PKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS 866
P+KK + T + +E SK + K S RS
Sbjct: 302 PEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRS 349
Score = 32.3 bits (72), Expect = 2.1
Identities = 24/104 (23%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
R +L S + ++ EE+ R ++ + R D E R S D + + +E R
Sbjct: 139 RASLTSRSQELDNKNVREEESRVHKNTE----DRGDAEIKERSTSRDR--KQKEELKEDR 192
Query: 77 RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+ RE+D D+++++++ R E + + A+ P +++KD
Sbjct: 193 KPREKDKDKEKAKENGGNRHREGE---RERAKARARPDNERQKD 233
Score = 32.3 bits (72), Expect = 2.1
Identities = 25/108 (23%), Positives = 46/108 (42%), Gaps = 2/108 (1%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSP-RDRDYFDYSRSDYEHSRRGRSYDSSMESR-NRDRE 74
RE + +N+ E +ERS RDR + + D + + + + + E+ NR RE
Sbjct: 155 REEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHRE 214
Query: 75 KRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKDEL 122
RER + R + + G R + + + + K+K+ L
Sbjct: 215 GERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
Score = 32.3 bits (72), Expect = 2.1
Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 6 AQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSS 65
A+IK S R+ + + P ++ +++E++ + + + R R+ +
Sbjct: 171 AEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKEN------GGNRHREGERERAKARA 224
Query: 66 MESRNRDREK-RRERERDTDRKRSRKSPSPGRRNPE 100
R +++ RER+RD++RK+ + S G + E
Sbjct: 225 RPDNERQKDRGNRERDRDSERKKETERKSEGGKEKE 260
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 59.3 bits (142), Expect = 2e-08
Identities = 53/216 (24%), Positives = 92/216 (42%), Gaps = 29/216 (13%)
Query: 692 SSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEH 751
+S S S+E D+ ++ S + +G + + + + DRKQKE +E
Sbjct: 140 ASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR--------DRKQKEELKED 191
Query: 752 GHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHID 811
R RE+ +K + + + G+ R+ + + P R +RD++
Sbjct: 192 -----RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRD---- 242
Query: 812 LENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRS-DEDR 870
+KK ER+ SE K R++D + R +D+ K ++ R +G S D DR
Sbjct: 243 ------SERKKETERK---SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDR 293
Query: 871 YQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAK 906
+N + EK S S + SKK D + S A+
Sbjct: 294 EKNREHDKPEKKSASSGEM--SKKLSDGTFKDSKAE 327
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 22/194 (11%)
Query: 721 GHGKTRSKEVDKLI-----RNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGS 775
GH R+ E+ ++I ++D ++ E G + R RS++ ++N
Sbjct: 98 GHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREE 157
Query: 776 NWRDPITKYTSDK-DVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENE 834
R + K T D+ D + + SR DR Q+ + + K P++K ++ + EN
Sbjct: 158 ESR--VHKNTEDRGDAEIKERSTSR---DRKQKEELKEDRK---PREKDKDKEKA-KENG 208
Query: 835 KHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKK 894
+ HR + E R K R++ +K G+R + DR +ER+ E + R SE +E ++
Sbjct: 209 GNRHR--EGERERAKARARPDNERQKDRGNR-ERDR---DSERKKE-TERKSEGGKEKER 261
Query: 895 NQDRRREKSPAKQK 908
+DR RE+ K K
Sbjct: 262 LRDRDRERDRDKGK 275
Score = 41.2 bits (95), Expect = 0.004
Identities = 35/178 (19%), Positives = 72/178 (40%), Gaps = 16/178 (8%)
Query: 9 KPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMES 68
K + G+ RE + + D +++R R+RD + + E G +
Sbjct: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRD 264
Query: 69 RN--RDREKRRERER----------DTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATK 116
R+ RDR+K ++R+R D DR+++R+ P +++ +S S D
Sbjct: 265 RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKS-ASSGEMSKKLSDGTFKD 323
Query: 117 KKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKNSLAYQRMSWEALKKSINGLINKVN 174
K + + TR + R + + + +S ++L ++G+ N+ N
Sbjct: 324 SKAETETEISTRASKSLTTKTSKRRSKNSVEGRKE---DNISAKSLDSIVSGINNEPN 378
Score = 35.8 bits (81), Expect = 0.19
Identities = 44/244 (18%), Positives = 94/244 (38%), Gaps = 23/244 (9%)
Query: 641 DELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSS--DSDSDSSDSSSESSS 698
+E R H KNT + D E + S S + D + D D + +
Sbjct: 157 EESRVH-KNTE-----DRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGN 210
Query: 699 EESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRT 758
+ + + A ++ R+K G R++ + +K+ ER+ E G ++ R
Sbjct: 211 RHREGERERAKARARPDNERQKDRGNRE--------RDRDSERKKETERKSEGGKEKERL 262
Query: 759 ERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNN---YSRVANDRDQEMHID---L 812
R+R E+ RD+ R +++ D D R + + A+ + +
Sbjct: 263 -RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTF 321
Query: 813 ENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQ 872
++ + + + R + + R K+S R++D +K ++ SG ++ ++
Sbjct: 322 KDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQET 381
Query: 873 NGAE 876
+E
Sbjct: 382 TTSE 385
Score = 32.3 bits (72), Expect = 2.1
Identities = 24/104 (23%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 17 RENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKR 76
R +L S + ++ EE+ R ++ + R D E R S D + + +E R
Sbjct: 139 RASLTSRSQELDNKNVREEESRVHKNTE----DRGDAEIKERSTSRDR--KQKEELKEDR 192
Query: 77 RERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+ RE+D D+++++++ R E + + A+ P +++KD
Sbjct: 193 KPREKDKDKEKAKENGGNRHREGE---RERAKARARPDNERQKD 233
Score = 32.3 bits (72), Expect = 2.1
Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 6 AQIKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSS 65
A+IK S R+ + + P ++ +++E++ + + + R R+ +
Sbjct: 171 AEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKEN------GGNRHREGERERAKARA 224
Query: 66 MESRNRDREK-RRERERDTDRKRSRKSPSPGRRNPE 100
R +++ RER+RD++RK+ + S G + E
Sbjct: 225 RPDNERQKDRGNRERDRDSERKKETERKSEGGKEKE 260
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/297 (20%), Positives = 107/297 (36%), Gaps = 45/297 (15%)
Query: 657 QKPDVEQNKSSPS-SSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
+K ++ + K SPS + SAS + D + S S S H +
Sbjct: 1456 EKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1515
Query: 716 DVRK---------KGHGKTRSKEVDKLIRNQQTNDRK----------QKERRQEHGHQET 756
D ++ K K R K V + N++++ K Q E+ Q G +
Sbjct: 1516 DTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDK 1575
Query: 757 RTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKH 816
T + + H + SS + D + +N S + + DL++K
Sbjct: 1576 STVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKI 1635
Query: 817 GDPKKKR---------GERRN----------------SFSENEKHTHRIKDSENFRRKDR 851
+ K+ G RN S S+ H+ +E+ K +
Sbjct: 1636 VEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKK 1695
Query: 852 SKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
K KE + + + + G E EKS ++ + ++SKKN+D+ +EK QK
Sbjct: 1696 KKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1752
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/248 (22%), Positives = 102/248 (41%), Gaps = 17/248 (6%)
Query: 653 VIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSA 712
V+ + P+ +N + P S+ +E + S S SS + +S++ DS+ SS+
Sbjct: 1376 VLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEAR--TSDKHDSTRASSNKDF 1433
Query: 713 SAN-------DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSE 765
+ N D R+ K R ++ + R + K Q++ +E R ++ +
Sbjct: 1434 TPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG 1493
Query: 766 KHRDQNSSGSNWRDPIT-KYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRG 824
+ NSS S R P K T D P+E +D+E H+ LE ++ K+
Sbjct: 1494 DSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHV-LEARN---NKESS 1549
Query: 825 ERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSR 884
+ + N T +++ + + D+S K + SR D + E +E
Sbjct: 1550 GNKLLYILNPPET-QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPD-- 1606
Query: 885 YSEQSRES 892
Y+E ES
Sbjct: 1607 YNESDSES 1614
Score = 43.5 bits (101), Expect = 9e-04
Identities = 55/286 (19%), Positives = 109/286 (38%), Gaps = 51/286 (17%)
Query: 628 INFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSS-----SSASSSSESDS 682
+++ ++ GG E +T + ++ + + ++P+ S + D
Sbjct: 1232 VDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDD 1291
Query: 683 SDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDR 742
+S+ + S+ SS +S I + S+ +N V+ S+++ K T D
Sbjct: 1292 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKF-----TKDV 1346
Query: 743 KQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVAN 802
+ + E + E+ K RD + +K+ P +R N +
Sbjct: 1347 SHEIIQHEVKSSKNSASSEKGKTKDRDYS-------------VLEKENPEKRKN----ST 1389
Query: 803 DRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHS 862
++E ++D N+ G+ K S S++ K R D + R +K NR
Sbjct: 1390 QPEKESNLDRLNEQGNFK--------SLSQSSKEA-RTSDKHDSTRASSNKDFTPNRD-- 1438
Query: 863 GSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
++D D + YS R +KN+ RR+ SP++ K
Sbjct: 1439 -KKTDYD------------TREYSSSKRRDEKNELTRRKDSPSRNK 1471
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/204 (21%), Positives = 76/204 (37%), Gaps = 12/204 (5%)
Query: 646 HLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDS-S 704
++ N P+ V ++ Q S S S SSD ++ +++ E ESDS S
Sbjct: 1555 YILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSES 1614
Query: 705 SISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQK--ERRQEHGHQETRTERER 762
++S S+ ++ K + K V+K + T Q R Q H R
Sbjct: 1615 NVSVKEEESSGNISKD----LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH 1670
Query: 763 -----RSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHG 817
++ H SS + K +K + + + E+ ++ KH
Sbjct: 1671 SPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHK 1730
Query: 818 DPKKKRGERRNSFSENEKHTHRIK 841
KKK + ++ E EK ++K
Sbjct: 1731 HKKKKSKKNKDKEKEKEKDDQKVK 1754
Score = 40.8 bits (94), Expect = 0.006
Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 14/133 (10%)
Query: 639 LTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSS 698
L D++ E K + + + +N+S S S S S S S + S SS +SS + S
Sbjct: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS-AES 1689
Query: 699 EESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRT 758
++S + K H K EV + E+ Q+H H++ ++
Sbjct: 1690 QDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEV-------------ELEKSQKHKHKKKKS 1736
Query: 759 ERERRSEKHRDQN 771
++ + EK ++++
Sbjct: 1737 KKNKDKEKEKEKD 1749
Score = 38.9 bits (89), Expect = 0.022
Identities = 56/266 (21%), Positives = 102/266 (38%), Gaps = 33/266 (12%)
Query: 662 EQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKG 721
EQ + S S S SS S SS + S S S+ S S S S S + + ++G
Sbjct: 644 EQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRG 703
Query: 722 HGKTRS-KEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQN-SSGSNWRD 779
GK+R+ + + ++ R RR H +R+ + R + +N G R+
Sbjct: 704 RGKSRNYRSRSRSHGYHRSRSRSPPYRRY---HSRSRSPQAFRGQSPNKRNVPQGETERE 760
Query: 780 PITKYTSDKDVPSERNNYSRVANDRD---QEMHIDLENKHGD------------PKKKRG 824
+Y + Y R + RD +E + + E K+ + + +
Sbjct: 761 YFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPS 820
Query: 825 ERRNSFSENEKHTHRIKDS--ENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKS 882
R +FS I++S RR+D + ++ GS E + S
Sbjct: 821 ANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPE-----------KLS 869
Query: 883 SRYSEQSRESKKNQDRRREKSPAKQK 908
+R +++ K++++ E +P K
Sbjct: 870 ARDGHNQKDNTKSKEKESENAPGDGK 895
Score = 38.9 bits (89), Expect = 0.022
Identities = 49/268 (18%), Positives = 104/268 (38%), Gaps = 11/268 (4%)
Query: 645 EHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSS 704
E K ++ + D + P + S + S S+ + D + + + ++D S
Sbjct: 933 EENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGS 992
Query: 705 SISSHSSA--SANDVRKKGHG-KTRSKEVDKLIRNQQTNDRKQKERRQEHGHQE----TR 757
++S + A ++K G + RS + I+ + K + Q+ T
Sbjct: 993 AVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITG 1052
Query: 758 TERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHG 817
T R+ S+ ++ + + + K S KDV SE+ + E + L+NK
Sbjct: 1053 TPRKAHSKSAKEHQETKPVKEEKVKKDYS-KDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1111
Query: 818 DPKKKRGER--RNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGA 875
K+K E+ F + +++ +E + + K E + + ++D+ A
Sbjct: 1112 KRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK-MEPDTEKMDRTPEKDKISLSA 1170
Query: 876 ERRWEKSSRYSEQSRESKKNQDRRREKS 903
+ K +R + + S +N +E S
Sbjct: 1171 PAKKIKLNRETGKKIGSTENISNTKEPS 1198
Score = 33.9 bits (76), Expect = 0.71
Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 5/111 (4%)
Query: 10 PSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESR 69
P SG + +Y ++ S R RS YSRS + RRGR + SR
Sbjct: 655 PYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSP-PYPRRGRGKSRNYRSR 713
Query: 70 NRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+R R R R +R R+P+ QS + ++ P + +++
Sbjct: 714 SRSHGYHRSRSRSPPYRRYHSR----SRSPQAFRGQSPNKRNVPQGETERE 760
Score = 33.9 bits (76), Expect = 0.71
Identities = 37/168 (22%), Positives = 67/168 (39%), Gaps = 34/168 (20%)
Query: 8 IKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRR--------- 58
+ SS R + + R SS +D +++ DY +Y S+R
Sbjct: 1409 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT------DYDTREYSSSKRRDEKNELTR 1462
Query: 59 -----GRSYDSSMESRNRDREKRRERERDT-DRKRSRKSPSPGRRNPETSVT-------- 104
R+ DS+ +N+ RE+R ++ T D K+S SPS R+ + T
Sbjct: 1463 RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNE 1522
Query: 105 QSSSAQDEPATKKKKDELDPLLTRTGGA-----YIPPAKLRMMQEQIT 147
++ S P ++K L+ + + P + ++ +EQIT
Sbjct: 1523 ETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQIT 1570
Score = 33.1 bits (74), Expect = 1.2
Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 3/69 (4%)
Query: 28 SPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKR 87
S E+ Y EQ R ++ YS S Y SR +Y S R R R R R
Sbjct: 637 SREEFYREQRRL-KEESKSPYSGSSY--SRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSY 693
Query: 88 SRKSPSPGR 96
SR P P R
Sbjct: 694 SRSPPYPRR 702
Score = 33.1 bits (74), Expect = 1.2
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDT 83
++NS+ ++ +R ++ S+S E +R +DS+ S N+D R+++ D
Sbjct: 1385 RKNSTQPEKESNLDRLNEQGNFKSLSQSSKE-ARTSDKHDSTRASSNKDFTPNRDKKTDY 1443
Query: 84 DRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
D + S +N T S S + A+ +K
Sbjct: 1444 DTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQK 1478
Score = 30.8 bits (68), Expect = 6.0
Identities = 17/75 (22%), Positives = 33/75 (44%)
Query: 49 SRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSS 108
SRS + RS+ SS S K+++++++ + + K +++ T V S
Sbjct: 1667 SRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS 1726
Query: 109 AQDEPATKKKKDELD 123
+ + KK K D
Sbjct: 1727 QKHKHKKKKSKKNKD 1741
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/297 (20%), Positives = 107/297 (36%), Gaps = 45/297 (15%)
Query: 657 QKPDVEQNKSSPS-SSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAN 715
+K ++ + K SPS + SAS + D + S S S H +
Sbjct: 1490 EKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1549
Query: 716 DVRK---------KGHGKTRSKEVDKLIRNQQTNDRK----------QKERRQEHGHQET 756
D ++ K K R K V + N++++ K Q E+ Q G +
Sbjct: 1550 DTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDK 1609
Query: 757 RTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKH 816
T + + H + SS + D + +N S + + DL++K
Sbjct: 1610 STVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKI 1669
Query: 817 GDPKKKR---------GERRN----------------SFSENEKHTHRIKDSENFRRKDR 851
+ K+ G RN S S+ H+ +E+ K +
Sbjct: 1670 VEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKK 1729
Query: 852 SKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
K KE + + + + G E EKS ++ + ++SKKN+D+ +EK QK
Sbjct: 1730 KKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1786
Score = 44.7 bits (104), Expect = 4e-04
Identities = 56/248 (22%), Positives = 102/248 (41%), Gaps = 17/248 (6%)
Query: 653 VIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSA 712
V+ + P+ +N + P S+ +E + S S SS + +S++ DS+ SS+
Sbjct: 1410 VLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEAR--TSDKHDSTRASSNKDF 1467
Query: 713 SAN-------DVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSE 765
+ N D R+ K R ++ + R + K Q++ +E R ++ +
Sbjct: 1468 TPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG 1527
Query: 766 KHRDQNSSGSNWRDPIT-KYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRG 824
+ NSS S R P K T D P+E +D+E H+ LE ++ K+
Sbjct: 1528 DSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHV-LEARN---NKESS 1583
Query: 825 ERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSR 884
+ + N T +++ + + D+S K + SR D + E +E
Sbjct: 1584 GNKLLYILNPPET-QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPD-- 1640
Query: 885 YSEQSRES 892
Y+E ES
Sbjct: 1641 YNESDSES 1648
Score = 43.5 bits (101), Expect = 9e-04
Identities = 55/286 (19%), Positives = 109/286 (38%), Gaps = 51/286 (17%)
Query: 628 INFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSS-----SSASSSSESDS 682
+++ ++ GG E +T + ++ + + ++P+ S + D
Sbjct: 1266 VDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDD 1325
Query: 683 SDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDR 742
+S+ + S+ SS +S I + S+ +N V+ S+++ K T D
Sbjct: 1326 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKF-----TKDV 1380
Query: 743 KQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVAN 802
+ + E + E+ K RD + +K+ P +R N +
Sbjct: 1381 SHEIIQHEVKSSKNSASSEKGKTKDRDYS-------------VLEKENPEKRKN----ST 1423
Query: 803 DRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHS 862
++E ++D N+ G+ K S S++ K R D + R +K NR
Sbjct: 1424 QPEKESNLDRLNEQGNFK--------SLSQSSKEA-RTSDKHDSTRASSNKDFTPNRD-- 1472
Query: 863 GSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
++D D + YS R +KN+ RR+ SP++ K
Sbjct: 1473 -KKTDYD------------TREYSSSKRRDEKNELTRRKDSPSRNK 1505
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/204 (21%), Positives = 76/204 (37%), Gaps = 12/204 (5%)
Query: 646 HLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDS-S 704
++ N P+ V ++ Q S S S SSD ++ +++ E ESDS S
Sbjct: 1589 YILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSES 1648
Query: 705 SISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQK--ERRQEHGHQETRTERER 762
++S S+ ++ K + K V+K + T Q R Q H R
Sbjct: 1649 NVSVKEEESSGNISKD----LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH 1704
Query: 763 -----RSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHG 817
++ H SS + K +K + + + E+ ++ KH
Sbjct: 1705 SPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHK 1764
Query: 818 DPKKKRGERRNSFSENEKHTHRIK 841
KKK + ++ E EK ++K
Sbjct: 1765 HKKKKSKKNKDKEKEKEKDDQKVK 1788
Score = 40.8 bits (94), Expect = 0.006
Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 14/133 (10%)
Query: 639 LTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSS 698
L D++ E K + + + +N+S S S S S S S + S SS +SS + S
Sbjct: 1665 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS-AES 1723
Query: 699 EESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRT 758
++S + K H K EV + E+ Q+H H++ ++
Sbjct: 1724 QDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEV-------------ELEKSQKHKHKKKKS 1770
Query: 759 ERERRSEKHRDQN 771
++ + EK ++++
Sbjct: 1771 KKNKDKEKEKEKD 1783
Score = 38.9 bits (89), Expect = 0.022
Identities = 57/271 (21%), Positives = 105/271 (38%), Gaps = 33/271 (12%)
Query: 657 QKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASAND 716
+K E+ +S S S S SS S SS + S S S+ S S S S S + +
Sbjct: 673 KKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPP 732
Query: 717 VRKKGHGKTRS-KEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQN-SSG 774
++G GK+R+ + + ++ R RR H +R+ + R + +N G
Sbjct: 733 YPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRY---HSRSRSPQAFRGQSPNKRNVPQG 789
Query: 775 SNWRDPITKYTSDKDVPSERNNYSRVANDRD---QEMHIDLENKHGD------------P 819
R+ +Y + Y R + RD +E + + E K+ +
Sbjct: 790 ETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGA 849
Query: 820 KKKRGERRNSFSENEKHTHRIKDS--ENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAER 877
+ + R +FS I++S RR+D + ++ GS E
Sbjct: 850 QPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPE--------- 900
Query: 878 RWEKSSRYSEQSRESKKNQDRRREKSPAKQK 908
+ S+R +++ K++++ E +P K
Sbjct: 901 --KLSARDGHNQKDNTKSKEKESENAPGDGK 929
Score = 38.9 bits (89), Expect = 0.022
Identities = 49/268 (18%), Positives = 104/268 (38%), Gaps = 11/268 (4%)
Query: 645 EHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSS 704
E K ++ + D + P + S + S S+ + D + + + ++D S
Sbjct: 967 EENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGS 1026
Query: 705 SISSHSSA--SANDVRKKGHG-KTRSKEVDKLIRNQQTNDRKQKERRQEHGHQE----TR 757
++S + A ++K G + RS + I+ + K + Q+ T
Sbjct: 1027 AVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITG 1086
Query: 758 TERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHG 817
T R+ S+ ++ + + + K S KDV SE+ + E + L+NK
Sbjct: 1087 TPRKAHSKSAKEHQETKPVKEEKVKKDYS-KDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1145
Query: 818 DPKKKRGER--RNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGA 875
K+K E+ F + +++ +E + + K E + + ++D+ A
Sbjct: 1146 KRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK-MEPDTEKMDRTPEKDKISLSA 1204
Query: 876 ERRWEKSSRYSEQSRESKKNQDRRREKS 903
+ K +R + + S +N +E S
Sbjct: 1205 PAKKIKLNRETGKKIGSTENISNTKEPS 1232
Score = 33.9 bits (76), Expect = 0.71
Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 5/111 (4%)
Query: 10 PSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESR 69
P SG + +Y ++ S R RS YSRS + RRGR + SR
Sbjct: 689 PYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSP-PYPRRGRGKSRNYRSR 747
Query: 70 NRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKKKD 120
+R R R R +R R+P+ QS + ++ P + +++
Sbjct: 748 SRSHGYHRSRSRSPPYRRYHSR----SRSPQAFRGQSPNKRNVPQGETERE 794
Score = 33.9 bits (76), Expect = 0.71
Identities = 37/168 (22%), Positives = 67/168 (39%), Gaps = 34/168 (20%)
Query: 8 IKPSSGHDRRENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRR--------- 58
+ SS R + + R SS +D +++ DY +Y S+R
Sbjct: 1443 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT------DYDTREYSSSKRRDEKNELTR 1496
Query: 59 -----GRSYDSSMESRNRDREKRRERERDT-DRKRSRKSPSPGRRNPETSVT-------- 104
R+ DS+ +N+ RE+R ++ T D K+S SPS R+ + T
Sbjct: 1497 RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNE 1556
Query: 105 QSSSAQDEPATKKKKDELDPLLTRTGGA-----YIPPAKLRMMQEQIT 147
++ S P ++K L+ + + P + ++ +EQIT
Sbjct: 1557 ETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQIT 1604
Score = 33.1 bits (74), Expect = 1.2
Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 24 QRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRRERERDT 83
++NS+ ++ +R ++ S+S E +R +DS+ S N+D R+++ D
Sbjct: 1419 RKNSTQPEKESNLDRLNEQGNFKSLSQSSKE-ARTSDKHDSTRASSNKDFTPNRDKKTDY 1477
Query: 84 DRKRSRKSPSPGRRNPETSVTQSSSAQDEPATKKK 118
D + S +N T S S + A+ +K
Sbjct: 1478 DTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQK 1512
Score = 32.0 bits (71), Expect = 2.7
Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 2/79 (2%)
Query: 18 ENLNSYQRNSSPEDRYEEQERSPRDRDYFDYSRSDYEHSRRGRSYDSSMESRNRDREKRR 77
E N + + + +++ R R YS S Y SR +Y S R R R
Sbjct: 660 EFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSY--SRSSYTYSKSRSGSTRSRSYSR 717
Query: 78 ERERDTDRKRSRKSPSPGR 96
R R SR P P R
Sbjct: 718 SFSRSHSRSYSRSPPYPRR 736
Score = 30.8 bits (68), Expect = 6.0
Identities = 17/75 (22%), Positives = 33/75 (44%)
Query: 49 SRSDYEHSRRGRSYDSSMESRNRDREKRRERERDTDRKRSRKSPSPGRRNPETSVTQSSS 108
SRS + RS+ SS S K+++++++ + + K +++ T V S
Sbjct: 1701 SRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS 1760
Query: 109 AQDEPATKKKKDELD 123
+ + KK K D
Sbjct: 1761 QKHKHKKKKSKKNKD 1775
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 58.9 bits (141), Expect = 2e-08
Identities = 52/154 (33%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Query: 618 RDNPRNTRFAINFFTSIGLGGLTDELR-EHLK-NTPKVIVAQK---PDVEQNKSSPSSSS 672
++ PR RF + F + + LR E L N P +K + N+S +SSS
Sbjct: 92 KEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSS 151
Query: 673 SASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDK 732
S+SSSS S SS S S SS SSS SSS S SSS SS SS S + K H K + +K
Sbjct: 152 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFS----KPH-KLMKEHKEK 206
Query: 733 LIRNQQTNDRKQKERRQEHGHQETRTERERRSEK 766
++ + + KE ++H + ++ + K
Sbjct: 207 PSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK 240
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/191 (21%), Positives = 75/191 (39%), Gaps = 11/191 (5%)
Query: 655 VAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDS------SSESSSEESDSSSISS 708
+ K V+ K S +S S D D +DS SS+S SE+ +S SS
Sbjct: 327 IKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSS 386
Query: 709 HSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHR 768
SS+S + + G RS ++++ ++D +++ E ++ ER R
Sbjct: 387 SSSSSFTPSQTRQQGPLRS-----IMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSR 441
Query: 769 DQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRN 828
+ S S+ D + S + N++ E+ ++ D + K GE
Sbjct: 442 SRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDK 501
Query: 829 SFSENEKHTHR 839
++ + HR
Sbjct: 502 AYLDELVELHR 512
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,140,140
Number of Sequences: 37866
Number of extensions: 1653992
Number of successful extensions: 45195
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 751
Number of HSP's successfully gapped in prelim test: 757
Number of HSP's that attempted gapping in prelim test: 17678
Number of HSP's gapped (non-prelim): 15426
length of query: 908
length of database: 18,247,518
effective HSP length: 111
effective length of query: 797
effective length of database: 14,044,392
effective search space: 11193380424
effective search space used: 11193380424
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.