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Search of human proteins with 55742730
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55742730 storkhead box 2 [Homo sapiens]
(926 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55742730 storkhead box 2 [Homo sapiens] 1880 0.0
gi|194328691 storkhead box 1 isoform a [Homo sapiens] 256 5e-68
gi|63025200 storkhead box 1 isoform a [Homo sapiens] 256 5e-68
gi|194328693 storkhead box 1 isoform d [Homo sapiens] 247 3e-65
gi|194328687 storkhead box 1 isoform b [Homo sapiens] 129 2e-29
gi|194328689 storkhead box 1 isoform c [Homo sapiens] 70 9e-12
gi|28559039 mediator complex subunit 1 [Homo sapiens] 51 6e-06
gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens] 50 1e-05
gi|209862849 Nance-Horan syndrome protein isoform 2 [Homo sapiens] 50 1e-05
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 48 4e-05
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 47 1e-04
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 47 1e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 46 1e-04
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 46 1e-04
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 45 4e-04
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 43 0.001
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 43 0.001
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 43 0.001
gi|213385278 TNF receptor-associated factor 3 interacting protei... 43 0.001
gi|217330641 IWS1 homolog [Homo sapiens] 43 0.001
gi|168229156 NFKB activating protein [Homo sapiens] 42 0.002
gi|148727255 microtubule associated serine/threonine kinase fami... 42 0.003
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 42 0.003
gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform... 41 0.005
gi|38788260 bromodomain PHD finger transcription factor isoform ... 41 0.005
gi|38788274 bromodomain PHD finger transcription factor isoform ... 41 0.005
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 41 0.006
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 41 0.006
gi|55750053 atrophin-1 [Homo sapiens] 41 0.006
gi|55750041 atrophin-1 [Homo sapiens] 41 0.006
>gi|55742730 storkhead box 2 [Homo sapiens]
Length = 926
Score = 1880 bits (4870), Expect = 0.0
Identities = 926/926 (100%), Positives = 926/926 (100%)
Query: 1 MKKTRSTTLRRAWPSSDFSDRASDRMRSRSEKDYRLHKRFPAAFAPQASRGYMTSGDVSP 60
MKKTRSTTLRRAWPSSDFSDRASDRMRSRSEKDYRLHKRFPAAFAPQASRGYMTSGDVSP
Sbjct: 1 MKKTRSTTLRRAWPSSDFSDRASDRMRSRSEKDYRLHKRFPAAFAPQASRGYMTSGDVSP 60
Query: 61 ISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTL 120
ISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTL
Sbjct: 61 ISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTL 120
Query: 121 NTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITP 180
NTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITP
Sbjct: 121 NTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITP 180
Query: 181 SASGCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKDCKDPYCPPSLCQVPPTEKS 240
SASGCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKDCKDPYCPPSLCQVPPTEKS
Sbjct: 181 SASGCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKDCKDPYCPPSLCQVPPTEKS 240
Query: 241 KSTVNFSYKTETLSKPKDSEKQSKKFGLKLFRLSFKKDKTKQLANFSAQFPPEEWPLRDE 300
KSTVNFSYKTETLSKPKDSEKQSKKFGLKLFRLSFKKDKTKQLANFSAQFPPEEWPLRDE
Sbjct: 241 KSTVNFSYKTETLSKPKDSEKQSKKFGLKLFRLSFKKDKTKQLANFSAQFPPEEWPLRDE 300
Query: 301 DTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKS 360
DTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKS
Sbjct: 301 DTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKS 360
Query: 361 RTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDN 420
RTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDN
Sbjct: 361 RTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDN 420
Query: 421 FIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSR 480
FIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSR
Sbjct: 421 FIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSR 480
Query: 481 NERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVS 540
NERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVS
Sbjct: 481 NERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVS 540
Query: 541 LQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDY 600
LQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDY
Sbjct: 541 LQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDY 600
Query: 601 FQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKG 660
FQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKG
Sbjct: 601 FQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKG 660
Query: 661 PGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSS 720
PGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSS
Sbjct: 661 PGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSS 720
Query: 721 LSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDD 780
LSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDD
Sbjct: 721 LSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDD 780
Query: 781 DSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATH 840
DSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATH
Sbjct: 781 DSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATH 840
Query: 841 SARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAGPAFNFRA 900
SARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAGPAFNFRA
Sbjct: 841 SARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAGPAFNFRA 900
Query: 901 SAEPPTNEAEKLQKPSNCLQASVTSV 926
SAEPPTNEAEKLQKPSNCLQASVTSV
Sbjct: 901 SAEPPTNEAEKLQKPSNCLQASVTSV 926
>gi|194328691 storkhead box 1 isoform a [Homo sapiens]
Length = 989
Score = 256 bits (655), Expect = 5e-68
Identities = 262/909 (28%), Positives = 404/909 (44%), Gaps = 133/909 (14%)
Query: 56 GDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEI 115
GDV P+ M+PI+QSQF+PLGE+LC AIS MN+A+ VTQE+L+E L +PG+ PS++I
Sbjct: 104 GDVFPVQMNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDI 163
Query: 116 LRHTLNTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQP 175
L TL TL++ERKIY T +GYFIVTPQTYFIT + + N + +P P
Sbjct: 164 LYTTLGTLIKERKIYHTGEGYFIVTPQTYFITNTTTQENKR------MLPSDESRLMPAS 217
Query: 176 GTITPSASGC---VRERTLPRNHCDSCHCCREDVHS---THAPTLQRKSAKDCKDPYCPP 229
T S C +E P +HC SC C R D+H+ AP + K +
Sbjct: 218 MTYLVSMESCAESAQENAAPISHCQSCQCFR-DMHTQDVQEAPVAAEVTRKSHRGLGESV 276
Query: 230 SLCQVPPTEKSKSTVNFSYKTETLSKPKDSEKQSKKFGLK-LFRLSFKKDKTK-QLANFS 287
S Q S + + T+ L +D EK KKFG L+R +K+K K + ++FS
Sbjct: 277 SWVQNGAVSVS-AEHHICESTKPLPYTRDKEK-GKKFGFSLLWRSLSRKEKPKTEHSSFS 334
Query: 288 AQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKA 347
AQFPPEEWP+RDED IPR+VE EII+RINP LTV+N+++HT LM+K EE+K S+
Sbjct: 335 AQFPPEEWPVRDEDDLDNIPRDVEHEIIKRINPILTVDNLIKHTVLMQKYEEQKKYNSQG 394
Query: 348 GSS---------AHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAER--E 396
S+ G K+ K G+ S ++ S+ I E+ +
Sbjct: 395 TSTDMLTIGHKYPSKEGVKKRQGLSAKPQGQGHSRRDRHKARNQGSEFQPGSIRLEKHPK 454
Query: 397 YDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFP 456
P+ R+ + + + T VL SH + K+R PF
Sbjct: 455 LPATQPIPRIKSPNEMVGQKP-----LGEITTVLGSHL-----------IYKKRISNPFQ 498
Query: 457 EPS-RGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEG 515
S RGS+ SK H+ + + S+ K ++ RS+D+S+ G + E AE
Sbjct: 499 GLSHRGSTISKGHKIQKTSDLKPSQTGPKEKPFQKPRSLDSSRIFDGKAK----EPYAE- 553
Query: 516 CSQDDQTPSQS-YIDDSTLRPAQTVSLQRAHISSTSYKEV------CIP--------EIV 560
+D+ ++S YI+D T++P R H+ S + + C P E+
Sbjct: 554 -QPNDKMEAESIYINDPTVKPINDDF--RGHLFSHPQQSMLQNDGKCCPFMESMLRYEVY 610
Query: 561 SGS---------KEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVL 611
G K S L E + P SLPS G S T +A + +
Sbjct: 611 GGENEVIPEVLRKSHSHFDKLGETKQTPHSLPSRGASFSDRTPSACRLVDNTIHQFQNLG 670
Query: 612 TAPSPLGKN------KEDHDTLTL-----AEGVKKLSPSDRQVPHSSREPVGHKEESPKG 660
P+G N ++D D+ L + + S + Q+ + + ++ E G
Sbjct: 671 LLDYPVGVNPLRQAARQDKDSEELLRKGFVQDAETTSLENEQLSNDDQALYQNEVEDDDG 730
Query: 661 ----------------------PGGGPAASGGVAEG--IANGRLVQHHGAEPSSLDKRKE 696
PG + G ++G + ++++ E +S +R E
Sbjct: 731 ACSSLYLEEDDISENDDLRQMLPGHSQYSFTGGSQGNHLGKQKVIERSLTEYNSTMERVE 790
Query: 697 --IFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAM 754
+ ++ +KP + + +LS + A G + EPS+ +
Sbjct: 791 SQVLKRNECYKPTGLHATPGESQEPNLSAESCGLNSGAQF--GFNYEEEPSVAKCVQASA 848
Query: 755 PASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDL 814
PA +R FDYY+ E ++T + ++ Q +E +
Sbjct: 849 PADER----------IFDYYSARKASFEAE-VIQDTIGDTGKKPASWSQSPQNQEMRKHF 897
Query: 815 QRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSI 874
+KF+ T P + + + HS L+ ++ S+ DSG +SPRT +SL SN S I
Sbjct: 898 PQKFQLFNTSHMPV---LAQDVQYEHS-HLEGTENHSMAGDSGIDSPRT-QSLGSNNSVI 952
Query: 875 VES-NRRQN 882
++ RRQN
Sbjct: 953 LDGLKRRQN 961
>gi|63025200 storkhead box 1 isoform a [Homo sapiens]
Length = 989
Score = 256 bits (655), Expect = 5e-68
Identities = 262/909 (28%), Positives = 404/909 (44%), Gaps = 133/909 (14%)
Query: 56 GDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEI 115
GDV P+ M+PI+QSQF+PLGE+LC AIS MN+A+ VTQE+L+E L +PG+ PS++I
Sbjct: 104 GDVFPVQMNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDI 163
Query: 116 LRHTLNTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQP 175
L TL TL++ERKIY T +GYFIVTPQTYFIT + + N + +P P
Sbjct: 164 LYTTLGTLIKERKIYHTGEGYFIVTPQTYFITNTTTQENKR------MLPSDESRLMPAS 217
Query: 176 GTITPSASGC---VRERTLPRNHCDSCHCCREDVHS---THAPTLQRKSAKDCKDPYCPP 229
T S C +E P +HC SC C R D+H+ AP + K +
Sbjct: 218 MTYLVSMESCAESAQENAAPISHCQSCQCFR-DMHTQDVQEAPVAAEVTRKSHRGLGESV 276
Query: 230 SLCQVPPTEKSKSTVNFSYKTETLSKPKDSEKQSKKFGLK-LFRLSFKKDKTK-QLANFS 287
S Q S + + T+ L +D EK KKFG L+R +K+K K + ++FS
Sbjct: 277 SWVQNGAVSVS-AEHHICESTKPLPYTRDKEK-GKKFGFSLLWRSLSRKEKPKTEHSSFS 334
Query: 288 AQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKA 347
AQFPPEEWP+RDED IPR+VE EII+RINP LTV+N+++HT LM+K EE+K S+
Sbjct: 335 AQFPPEEWPVRDEDDLDNIPRDVEHEIIKRINPILTVDNLIKHTVLMQKYEEQKKYNSQG 394
Query: 348 GSS---------AHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAER--E 396
S+ G K+ K G+ S ++ S+ I E+ +
Sbjct: 395 TSTDMLTIGHKYPSKEGVKKRQGLSAKPQGQGHSRRDRHKARNQGSEFQPGSIRLEKHPK 454
Query: 397 YDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFP 456
P+ R+ + + + T VL SH + K+R PF
Sbjct: 455 LPATQPIPRIKSPNEMVGQKP-----LGEITTVLGSHL-----------IYKKRISNPFQ 498
Query: 457 EPS-RGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEG 515
S RGS+ SK H+ + + S+ K ++ RS+D+S+ G + E AE
Sbjct: 499 GLSHRGSTISKGHKIQKTSDLKPSQTGPKEKPFQKPRSLDSSRIFDGKAK----EPYAE- 553
Query: 516 CSQDDQTPSQS-YIDDSTLRPAQTVSLQRAHISSTSYKEV------CIP--------EIV 560
+D+ ++S YI+D T++P R H+ S + + C P E+
Sbjct: 554 -QPNDKMEAESIYINDPTVKPINDDF--RGHLFSHPQQSMLQNDGKCCPFMESMLRYEVY 610
Query: 561 SGS---------KEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVL 611
G K S L E + P SLPS G S T +A + +
Sbjct: 611 GGENEVIPEVLRKSHSHFDKLGETKQTPHSLPSRGASFSDRTPSACRLVDNTIHQFQNLG 670
Query: 612 TAPSPLGKN------KEDHDTLTL-----AEGVKKLSPSDRQVPHSSREPVGHKEESPKG 660
P+G N ++D D+ L + + S + Q+ + + ++ E G
Sbjct: 671 LLDYPVGVNPLRQAARQDKDSEELLRKGFVQDAETTSLENEQLSNDDQALYQNEVEDDDG 730
Query: 661 ----------------------PGGGPAASGGVAEG--IANGRLVQHHGAEPSSLDKRKE 696
PG + G ++G + ++++ E +S +R E
Sbjct: 731 ACSSLYLEEDDISENDDLRQMLPGHSQYSFTGGSQGNHLGKQKVIERSLTEYNSTMERVE 790
Query: 697 --IFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAM 754
+ ++ +KP + + +LS + A G + EPS+ +
Sbjct: 791 SQVLKRNECYKPTGLHATPGESQEPNLSAESCGLNSGAQF--GFNYEEEPSVAKCVQASA 848
Query: 755 PASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDL 814
PA +R FDYY+ E ++T + ++ Q +E +
Sbjct: 849 PADER----------IFDYYSARKASFEAE-VIQDTIGDTGKKPASWSQSPQNQEMRKHF 897
Query: 815 QRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSI 874
+KF+ T P + + + HS L+ ++ S+ DSG +SPRT +SL SN S I
Sbjct: 898 PQKFQLFNTSHMPV---LAQDVQYEHS-HLEGTENHSMAGDSGIDSPRT-QSLGSNNSVI 952
Query: 875 VES-NRRQN 882
++ RRQN
Sbjct: 953 LDGLKRRQN 961
>gi|194328693 storkhead box 1 isoform d [Homo sapiens]
Length = 879
Score = 247 bits (631), Expect = 3e-65
Identities = 258/902 (28%), Positives = 399/902 (44%), Gaps = 133/902 (14%)
Query: 63 MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTLNT 122
M+PI+QSQF+PLGE+LC AIS MN+A+ VTQE+L+E L +PG+ PS++IL TL T
Sbjct: 1 MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDILYTTLGT 60
Query: 123 LVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITPSA 182
L++ERKIY T +GYFIVTPQTYFIT + + N + +P P T S
Sbjct: 61 LIKERKIYHTGEGYFIVTPQTYFITNTTTQENKR------MLPSDESRLMPASMTYLVSM 114
Query: 183 SGC---VRERTLPRNHCDSCHCCREDVHS---THAPTLQRKSAKDCKDPYCPPSLCQVPP 236
C +E P +HC SC C R D+H+ AP + K + S Q
Sbjct: 115 ESCAESAQENAAPISHCQSCQCFR-DMHTQDVQEAPVAAEVTRKSHRGLGESVSWVQNGA 173
Query: 237 TEKSKSTVNFSYKTETLSKPKDSEKQSKKFGLK-LFRLSFKKDKTK-QLANFSAQFPPEE 294
S + + T+ L +D EK KKFG L+R +K+K K + ++FSAQFPPEE
Sbjct: 174 VSVS-AEHHICESTKPLPYTRDKEK-GKKFGFSLLWRSLSRKEKPKTEHSSFSAQFPPEE 231
Query: 295 WPLRDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSS---- 350
WP+RDED IPR+VE EII+RINP LTV+N+++HT LM+K EE+K S+ S+
Sbjct: 232 WPVRDEDDLDNIPRDVEHEIIKRINPILTVDNLIKHTVLMQKYEEQKKYNSQGTSTDMLT 291
Query: 351 -----AHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAER--EYDFCDPL 403
G K+ K G+ S ++ S+ I E+ + P+
Sbjct: 292 IGHKYPSKEGVKKRQGLSAKPQGQGHSRRDRHKARNQGSEFQPGSIRLEKHPKLPATQPI 351
Query: 404 TRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPS-RGS 462
R+ + + + T VL SH + K+R PF S RGS
Sbjct: 352 PRIKSPNEMVGQKP-----LGEITTVLGSHL-----------IYKKRISNPFQGLSHRGS 395
Query: 463 SHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQT 522
+ SK H+ + + S+ K ++ RS+D+S+ G + E AE +D+
Sbjct: 396 TISKGHKIQKTSDLKPSQTGPKEKPFQKPRSLDSSRIFDGKAK----EPYAE--QPNDKM 449
Query: 523 PSQS-YIDDSTLRPAQTVSLQRAHISSTSYKEV------CIP--------EIVSGS---- 563
++S YI+D T++P R H+ S + + C P E+ G
Sbjct: 450 EAESIYINDPTVKPINDDF--RGHLFSHPQQSMLQNDGKCCPFMESMLRYEVYGGENEVI 507
Query: 564 -----KEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLG 618
K S L E + P SLPS G S T +A + + P+G
Sbjct: 508 PEVLRKSHSHFDKLGETKQTPHSLPSRGASFSDRTPSACRLVDNTIHQFQNLGLLDYPVG 567
Query: 619 KN------KEDHDTLTL-----AEGVKKLSPSDRQVPHSSREPVGHKEESPKG------- 660
N ++D D+ L + + S + Q+ + + ++ E G
Sbjct: 568 VNPLRQAARQDKDSEELLRKGFVQDAETTSLENEQLSNDDQALYQNEVEDDDGACSSLYL 627
Query: 661 ---------------PGGGPAASGGVAEG--IANGRLVQHHGAEPSSLDKRKE--IFSKD 701
PG + G ++G + ++++ E +S +R E + ++
Sbjct: 628 EEDDISENDDLRQMLPGHSQYSFTGGSQGNHLGKQKVIERSLTEYNSTMERVESQVLKRN 687
Query: 702 TLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQ 761
+KP + + +LS + A G + EPS+ + PA +R
Sbjct: 688 ECYKPTGLHATPGESQEPNLSAESCGLNSGAQF--GFNYEEEPSVAKCVQASAPADER-- 743
Query: 762 ESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKN 821
FDYY+ E ++T + ++ Q +E + +KF+
Sbjct: 744 --------IFDYYSARKASFEAE-VIQDTIGDTGKKPASWSQSPQNQEMRKHFPQKFQLF 794
Query: 822 LTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVES-NRR 880
T P + + + HS L+ ++ S+ DSG +SPRT +SL SN S I++ RR
Sbjct: 795 NTSHMPV---LAQDVQYEHS-HLEGTENHSMAGDSGIDSPRT-QSLGSNNSVILDGLKRR 849
Query: 881 QN 882
QN
Sbjct: 850 QN 851
>gi|194328687 storkhead box 1 isoform b [Homo sapiens]
Length = 227
Score = 129 bits (323), Expect = 2e-29
Identities = 62/107 (57%), Positives = 81/107 (75%)
Query: 56 GDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEI 115
GDV P+ M+PI+QSQF+PLGE+LC AIS MN+A+ VTQE+L+E L +PG+ PS++I
Sbjct: 104 GDVFPVQMNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDI 163
Query: 116 LRHTLNTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDE 162
L TL TL++ERKIY T +GYFIVTPQTYFIT + + N + DE
Sbjct: 164 LYTTLGTLIKERKIYHTGEGYFIVTPQTYFITNTTTQENKRMLPSDE 210
>gi|194328689 storkhead box 1 isoform c [Homo sapiens]
Length = 169
Score = 70.1 bits (170), Expect = 9e-12
Identities = 32/52 (61%), Positives = 42/52 (80%)
Query: 56 GDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPG 107
GDV P+ M+PI+QSQF+PLGE+LC AIS MN+A+ VTQE+L+E L +PG
Sbjct: 104 GDVFPVQMNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPG 155
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 50.8 bits (120), Expect = 6e-06
Identities = 134/617 (21%), Positives = 212/617 (34%), Gaps = 112/617 (18%)
Query: 337 LEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAERE 396
L+ + +RS+ S+ S R + GKS SHS + P+ P
Sbjct: 988 LDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAG 1047
Query: 397 YDFCDPLTRVPREGCFIIE-HKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPF 455
P P I+ KG + + SH T VS
Sbjct: 1048 RSQTPPGVATPPIPKITIQIPKGTVMVGKPS-----SHSQYTSSGSVS------------ 1090
Query: 456 PEPSRGSSHSKVHRSHSHTQD---------RRSRNERSNKAKERSRSMDNSKGPLGASSL 506
SS SK H SHS + + S++E S+ +K S SM +S+G G+S
Sbjct: 1091 ------SSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSK-LSSSMYSSQGSSGSSQ- 1142
Query: 507 GTPEDLAEGCSQDDQTPSQSYIDDSTLR--PAQTVSLQRAHISSTSYKEVCIPEI-VSGS 563
++ SQ P S I L + T + SS + P I S S
Sbjct: 1143 ------SKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS 1196
Query: 564 KEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKN--- 620
+ P + L P KP P + S P + + TSS + + + S LG +
Sbjct: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKS-PISSGSGGSHMSGTSSSSGMKSSSGLGSSGSL 1255
Query: 621 --KEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESP-------------------- 658
K + + S S + S + K +SP
Sbjct: 1256 SQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVV 1315
Query: 659 -KGPGGGPAASG--GVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNS 715
GPGG G GV+ ++ + H ++E KD K S SV+S
Sbjct: 1316 TSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDK-SKVSTSGSSVDS 1374
Query: 716 YHKSSLS-----------LLKSH----PKTPADTL---PGRC--EKLEPSLGTSAAQAMP 755
K+S S ++ H P A PG E L P + +S P
Sbjct: 1375 SKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSP 1434
Query: 756 ---ASQRQQESGGNQEASFDYYNVSD-DDDSEEG---ANKNTEEEKNRED--VGTMQWLL 806
S + E G + Y + D +SE G A K+ + + +D ++
Sbjct: 1435 LISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYST 1494
Query: 807 EREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRES 866
E+ K+ ++K K+ ++ D +++ +HS + +S S I+ D S
Sbjct: 1495 EKHKKHKKEKKKVKDKD--RDRDRDKDRDKKKSHSIKPESWSKSPISSDQSL-------S 1545
Query: 867 LASNTSSIVESNRRQNP 883
+ SNT + R +P
Sbjct: 1546 MTSNTILSADRPSRLSP 1562
>gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens]
Length = 1630
Score = 50.1 bits (118), Expect = 1e-05
Identities = 83/378 (21%), Positives = 150/378 (39%), Gaps = 40/378 (10%)
Query: 518 QDDQTPSQSYIDDSTLRPAQ-TVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPG 576
+++ Y+++STL A + S R H ++ S E S SSA +
Sbjct: 1134 KEENNTDLPYLEESTLTTAALSPSKIRPHTANKSVSRQYSTEDTILSFLDSSAVEMGPDK 1193
Query: 577 KPPESLPSYGELNSCPTKTATD---DYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGV 633
E ++ N C +T T N + + V T P+ +N + EG
Sbjct: 1194 LHLEKNSTFDVKNRCDPETITSAGSSLLDSNVTKDQVRTETEPIPENTPTKNCAFPTEGF 1253
Query: 634 KKLSPS-----DRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEP 688
+++S + D ++ P E+ K P G E +A V ++
Sbjct: 1254 QRVSAARPNDLDGKIIQYGPGPDETLEQVQKAPSAG-------LEEVAQPESVDVITSQS 1306
Query: 689 SSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEP-SLG 747
S + ++ ++ FK H + + K ++ T ++ P +C K E + G
Sbjct: 1307 DSPTRATDVSNQ---FK--HQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASG 1361
Query: 748 TSAAQAMPASQRQQESGGNQEASFDYYNVSDD-------DDSE---EGANKNTEEEKNRE 797
SA A S+ ++ G EAS + SDD +DS+ EG + + + E
Sbjct: 1362 ISAKSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGVFVSPNKPRTTE 1421
Query: 798 DVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSG 857
D+ ++ R K + L RK ++++ + SS ++ SA + SS++T +
Sbjct: 1422 DLFA---VIHRSKRKVLGRKDSGDMSVRSKSRAPLSS---SSSSASSITSPSSNVTTPNS 1475
Query: 858 FNSPRT--RESLASNTSS 873
SP R + SNTS+
Sbjct: 1476 QRSPGLIYRNAKKSNTSN 1493
>gi|209862849 Nance-Horan syndrome protein isoform 2 [Homo sapiens]
Length = 1474
Score = 50.1 bits (118), Expect = 1e-05
Identities = 83/378 (21%), Positives = 150/378 (39%), Gaps = 40/378 (10%)
Query: 518 QDDQTPSQSYIDDSTLRPAQ-TVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPG 576
+++ Y+++STL A + S R H ++ S E S SSA +
Sbjct: 978 KEENNTDLPYLEESTLTTAALSPSKIRPHTANKSVSRQYSTEDTILSFLDSSAVEMGPDK 1037
Query: 577 KPPESLPSYGELNSCPTKTATD---DYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGV 633
E ++ N C +T T N + + V T P+ +N + EG
Sbjct: 1038 LHLEKNSTFDVKNRCDPETITSAGSSLLDSNVTKDQVRTETEPIPENTPTKNCAFPTEGF 1097
Query: 634 KKLSPS-----DRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEP 688
+++S + D ++ P E+ K P G E +A V ++
Sbjct: 1098 QRVSAARPNDLDGKIIQYGPGPDETLEQVQKAPSAG-------LEEVAQPESVDVITSQS 1150
Query: 689 SSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEP-SLG 747
S + ++ ++ FK H + + K ++ T ++ P +C K E + G
Sbjct: 1151 DSPTRATDVSNQ---FK--HQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASG 1205
Query: 748 TSAAQAMPASQRQQESGGNQEASFDYYNVSDD-------DDSE---EGANKNTEEEKNRE 797
SA A S+ ++ G EAS + SDD +DS+ EG + + + E
Sbjct: 1206 ISAKSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGVFVSPNKPRTTE 1265
Query: 798 DVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSG 857
D+ ++ R K + L RK ++++ + SS ++ SA + SS++T +
Sbjct: 1266 DLFA---VIHRSKRKVLGRKDSGDMSVRSKSRAPLSS---SSSSASSITSPSSNVTTPNS 1319
Query: 858 FNSPRT--RESLASNTSS 873
SP R + SNTS+
Sbjct: 1320 QRSPGLIYRNAKKSNTSN 1337
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 48.1 bits (113), Expect = 4e-05
Identities = 98/501 (19%), Positives = 186/501 (37%), Gaps = 62/501 (12%)
Query: 436 MTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRN---ERSNKAKERSR 492
+TP+ D +G + +E PE + + R + + ++ + E S+ A +
Sbjct: 328 VTPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELE 387
Query: 493 SMDNSKGPLGASSLGTPEDLAEGCSQDDQTP-SQSYIDDSTLRPA---------QTVSLQ 542
++ K P + S+ + G ++ S+ +D L P Q + ++
Sbjct: 388 ISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIE 447
Query: 543 RAHISSTSYKEVC--------------IPEIVSGSKEPSSACSLLEPGKPPESLPSYGEL 588
S +S E+ +P P S + EP + PE P + E
Sbjct: 448 DKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEA 507
Query: 589 NSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLT-LAEGVKKLSPSDRQVPHSS 647
+A Q + E + P+ K KE H L G ++ + +V S
Sbjct: 508 EELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSP 567
Query: 648 REPVGHKEESPKGPGGGP-----AASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDT 702
PV + S + P P AA + E +A S +K +++ K
Sbjct: 568 TPPVSPEVRSTE-PVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREK-L 625
Query: 703 LFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPS-LGTSAAQAMPASQRQQ 761
+ L ++ + SLS L+ + + R + E L AQ ++Q +
Sbjct: 626 CQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADE 685
Query: 762 ES-GGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTM-----------QWLLERE 809
+ QEAS + ++ +S++ A + + E+KNR+ + + Q L
Sbjct: 686 DQIRAEQEASLQ--KLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAA 743
Query: 810 KERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLAS 869
KE+ LQ+ E+ L + ++ + HSA L+ + SS + RE ++S
Sbjct: 744 KEKALQQLREQ----LEGERKEAVATLEKEHSAELERLCSSL--------EAKHREVVSS 791
Query: 870 NTSSIVESNRRQNPALSPAHG 890
I E+ +++ L G
Sbjct: 792 LQKKIQEAQQKEEAQLQKCLG 812
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 46.6 bits (109), Expect = 1e-04
Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 23/181 (12%)
Query: 339 EEKAQRSKAGSSAHHSGRSKK------SRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIP 392
EE+A+ +K+GSS+ GR K S + RK S+T+ SK PS ++ + P
Sbjct: 240 EERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPS--AYKEPP 297
Query: 393 AEREYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTE 452
D +P R + + D+ + H + L S +P S ++R
Sbjct: 298 KAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPR 357
Query: 453 MPFPEPSRGSSHSKVHRSHSHTQD-----------RRSRNERS----NKAKERSRSMDNS 497
P P R S H S+ D RRSR+ S K RSRS +S
Sbjct: 358 SPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSS 417
Query: 498 K 498
+
Sbjct: 418 R 418
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 46.6 bits (109), Expect = 1e-04
Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 23/181 (12%)
Query: 339 EEKAQRSKAGSSAHHSGRSKK------SRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIP 392
EE+A+ +K+GSS+ GR K S + RK S+T+ SK PS ++ + P
Sbjct: 240 EERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPS--AYKEPP 297
Query: 393 AEREYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTE 452
D +P R + + D+ + H + L S +P S ++R
Sbjct: 298 KAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPR 357
Query: 453 MPFPEPSRGSSHSKVHRSHSHTQD-----------RRSRNERS----NKAKERSRSMDNS 497
P P R S H S+ D RRSR+ S K RSRS +S
Sbjct: 358 SPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSS 417
Query: 498 K 498
+
Sbjct: 418 R 418
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 46.2 bits (108), Expect = 1e-04
Identities = 72/305 (23%), Positives = 124/305 (40%), Gaps = 30/305 (9%)
Query: 330 HTALMKKLEEEKAQRSKAGSS-AHHSGRSKKSRTHRKSHGKSRSHSKTRV-SKGDPSDGS 387
H+ + + RS++GSS + HS +SR+ +S KSRS S++R SK + S
Sbjct: 191 HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSP 250
Query: 388 HLDIPAEREYDFCDPLTRVPREGCFIIEH-------KGDNFIMHSNTNVLESHF-PMTPE 439
+ R + ++ + I++ K + H + + S E
Sbjct: 251 SKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVE 310
Query: 440 WDVSGELAKRRTEMPFPEPSRGSSHSK-----VHRSHSHTQDRRSRNERSNKAKERSRSM 494
+ G +++ R++ SR S SK RS S ++D+R +RS + + RSRS
Sbjct: 311 EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS-REESRSRSR 369
Query: 495 DNSKGPLGASSLGTPEDLAEGCS----QDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTS 550
SK + G+ D G S ++D SQS P+++VS +R H S S
Sbjct: 370 SRSKSE-RSRKRGSKRDSKAGSSKKKKKEDTDRSQS------RSPSRSVSKEREHAKSES 422
Query: 551 YKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETV 610
+ E + + K +LPS S K+A+ + + S +
Sbjct: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS---KSASKTRSRSKSRSRSA 479
Query: 611 LTAPS 615
+PS
Sbjct: 480 SRSPS 484
Score = 38.5 bits (88), Expect = 0.029
Identities = 63/271 (23%), Positives = 101/271 (37%), Gaps = 21/271 (7%)
Query: 239 KSKSTVNFSYKTETLSKPKDSEKQSKKFGLKLFRLSFKKDKTKQLANF-SAQFPPEEWPL 297
+S+S K E P + +S+ R K +++ N + P P
Sbjct: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPS 292
Query: 298 RDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQ-RSKAGSSAHHSGR 356
R + + R E RR+ + +V R + K L + +++ RSK GS + R
Sbjct: 293 RHKSKSKSRSRSQE----RRVEEEKR-GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 357 SK---------KSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVP 407
SK +SR +S +SRS S+ +G D +++ D +R P
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 408 -REGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSK 466
R EH E+ S +K + +P SR S SK
Sbjct: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASK 467
Query: 467 VHRSHSHTQDRRSRNERSNKAKERSRSMDNS 497
RS S + RSR+ + ++ RSRS S
Sbjct: 468 T-RSRSKS---RSRSASRSPSRSRSRSHSRS 494
Score = 30.8 bits (68), Expect = 6.1
Identities = 17/67 (25%), Positives = 30/67 (44%)
Query: 459 SRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQ 518
SR SHS+ H++ RSR+ S + +SRS S + S + + +
Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 519 DDQTPSQ 525
++PS+
Sbjct: 246 KSRSPSK 252
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 46.2 bits (108), Expect = 1e-04
Identities = 70/256 (27%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 330 HTALMKKLEEEKAQRSKAGSSA--HHSG-----RSKKSRTHRKSHGKSRSHSKTRVSKGD 382
H + ++ +QRS G S HHS RS R+HR +S HS + S
Sbjct: 1686 HCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSH-HSPSERSHHS 1744
Query: 383 PSDGSHLDIPAEREYDFCDPLTRV---PREGCFIIEHKGDNFIMHSNTNVLESHFPMTPE 439
PS+ H P+ER + C P R P E H+ + H + + H P
Sbjct: 1745 PSERRHHS-PSERSH--CSPSERSHCSPSER----RHRSPSERRHHSPSEKSHHSPSERS 1797
Query: 440 WDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSK- 498
E RR P E SR S + HRS S + RS + ERS S
Sbjct: 1798 HHSPSE---RRRHSPL-ERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSH 1853
Query: 499 -GPLGASSLGTPEDLAEGCS-QDDQTPSQ-SYIDDSTLRPAQTVSLQRAHISSTSYKEVC 555
PL S E S + +PS+ S+ S +R +T +R+H SS
Sbjct: 1854 LSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRT--SERSHRSSCERTRHS 1911
Query: 556 IPEIVSGSKEPSSACS 571
E+ G + CS
Sbjct: 1912 PSEMRPGRPSGRNHCS 1927
Score = 41.2 bits (95), Expect = 0.005
Identities = 73/314 (23%), Positives = 128/314 (40%), Gaps = 66/314 (21%)
Query: 213 TLQRKSAKDCKDPYC-PPSLCQVPPTEKSKSTVNFSYKTETLSKP-----KDSEKQSKKF 266
T+Q +SA+ + Y P ++P S+S + F +T ++ +P KDS +SKK
Sbjct: 1432 TVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAF--QTASVGQPLRTVQKDSSSRSKK- 1488
Query: 267 GLKLFRLSFKKDKTKQLANFSAQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLTVEN 326
+F +++T + + P R P + V+ R + LT +
Sbjct: 1489 -------NFYRNETSSQESKNLSTPGTRVQARGRILPGS---PVKRTWHRHLKDKLTHKE 1538
Query: 327 VMRHTALMKKLEEEKAQRSKAGSSAHH----SGRSKKSRTHRKSHGKS-RSH-SKTRVSK 380
+ ++ ++R++ S + S RS++S R+ H S RSH S +R +
Sbjct: 1539 HNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNH 1598
Query: 381 GDPSDGSHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEW 440
PS+ S P++R + C P P C + +G +HS + SH
Sbjct: 1599 SSPSERSWRS-PSQRNH--CSP----PERSCHSLSERG----LHSPSQ--RSH------- 1638
Query: 441 DVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSR----------NERS----NK 486
+ ++ PS S S RSH + +RR R +ERS ++
Sbjct: 1639 -------RGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSE 1691
Query: 487 AKERSRSMDNSKGP 500
+ RS S + +GP
Sbjct: 1692 RRHRSPSQRSHRGP 1705
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 44.7 bits (104), Expect = 4e-04
Identities = 105/521 (20%), Positives = 184/521 (35%), Gaps = 51/521 (9%)
Query: 349 SSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPR 408
S+A HSG KK R +K K + + + + + IP++ E TR +
Sbjct: 419 STARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSS--TRRMK 476
Query: 409 EGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVH 468
C + S ++ L SH +W S + + SR S SK H
Sbjct: 477 SSC--------DRERSSRSSSLSSHHSSKRDWSKS----DKDVQSSLTHSSRDSYRSKSH 524
Query: 469 -RSHSHTQDR-RSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQS 526
+S+S R R+ ++ S+ ++ RS+S +SK + +P A S++ ++
Sbjct: 525 SQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTE- 583
Query: 527 YIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYG 586
P + Q ++ IP I P S +PG+ P PSY
Sbjct: 584 --------PLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSR---WKPGQKPWK-PSYE 631
Query: 587 ELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSP-SDRQVPH 645
+ KT Q S + S +K + ++ + K S S P
Sbjct: 632 RIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPR 691
Query: 646 SSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFK 705
S + S AS + R + S R ++ +
Sbjct: 692 SRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDD 751
Query: 706 PLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGG 765
+ + S K + K H + TL + K +S + S+ +
Sbjct: 752 GRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDR--SSCVRKYSESRSSLDYSS 809
Query: 766 NQEASFDYYNVSDDDDSEEGANKNT--EEEKNREDVGTMQWLLEREKERDLQRKFEKNLT 823
+ E S S + ++G + T ++EKNR G + ERE +R ++NL+
Sbjct: 810 DSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR---GEEKSKSERECPHSKKRTLKENLS 866
Query: 824 -----LLAPK---------ETDSSSNQRATHSARLDSMDSS 850
PK +++S+S + T +++ DS SS
Sbjct: 867 DHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSS 907
Score = 35.4 bits (80), Expect = 0.25
Identities = 63/293 (21%), Positives = 111/293 (37%), Gaps = 41/293 (13%)
Query: 123 LVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITPSA 182
+VR +I P P+ F++ +T + +IPD + S Q +++ S
Sbjct: 281 VVRPEEIPPVPENRFLLRRDMPVVTAEP----------EPKIPDVAPIVSDQKPSVSKSG 330
Query: 183 S-----GCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKDCKDPYCPPSLCQVPPT 237
G +R T PR+ SC +D S P + + + Y PPS +
Sbjct: 331 RKIKGRGTIRYHTPPRSR--SCSESDDDDSSETPPHWKEEMQR--LRAYRPPSGEKWSKG 386
Query: 238 EKSKSTVNFSYKTETLSKPKDSEKQSKKFG-LKLFRLS--FKKDKTKQLANFSAQFPPEE 294
+K + + +LS+ S + + L R S KK + ++ + ++
Sbjct: 387 DKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQK 446
Query: 295 WPLRDEDTPAT---IPREVEME--IIRRINPDLTVENVMRHTALMK----KLEEEKAQRS 345
R + T IP ++E RR+ E R ++L K + K+ +
Sbjct: 447 HCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKD 506
Query: 346 KAGSSAHHSGRSKKSRTHRKSH----------GKSRSHSKTRVSKGDPSDGSH 388
S H S S +S++H +S+ KS SHS++R S H
Sbjct: 507 VQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGH 559
Score = 35.4 bits (80), Expect = 0.25
Identities = 37/162 (22%), Positives = 64/162 (39%), Gaps = 1/162 (0%)
Query: 338 EEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREY 397
E RS++ S +S +SR+ SH +SRS S S+ SD S +
Sbjct: 687 ESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTS 746
Query: 398 DFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPE 457
D R R + + HS+++ H D S + K +
Sbjct: 747 ISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLD 806
Query: 458 PSRGSSHSKVHRSHS-HTQDRRSRNERSNKAKERSRSMDNSK 498
S S S V + S ++++ + ER++ +E++R + SK
Sbjct: 807 YSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSK 848
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 43.1 bits (100), Expect = 0.001
Identities = 56/225 (24%), Positives = 87/225 (38%), Gaps = 31/225 (13%)
Query: 477 RRSRNERSNKAKERSRSM----DNSKGPLGASSLGTPE--DLAEGCSQDDQTPSQSY--- 527
R+ R E+ K K R S+ D P + T E + A +DD+ P+ Y
Sbjct: 652 RKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDPNDPYRAL 711
Query: 528 -ID-DSTLRPAQTVSLQRAHISSTSYK-EVCIPEIVSGSKEPSSACSLLEPGKPPESLPS 584
ID D L ++ + +Q+ + TS E +P + SK+P + K E
Sbjct: 712 DIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKK-----KEKKHKEKERD 766
Query: 585 YGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVK---------K 635
+ K D++ T AP+P+ E D T A+G + K
Sbjct: 767 KEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTDECEDAKTEAQGEEDDAEGQDQDK 826
Query: 636 LSPSDRQVPH--SSREPVGHKEESPKGPGGGPAASGGVAEGIANG 678
SP ++ H E K++S K P G A+G E + NG
Sbjct: 827 KSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAG---EPVQNG 868
Score = 32.0 bits (71), Expect = 2.7
Identities = 42/199 (21%), Positives = 74/199 (37%), Gaps = 17/199 (8%)
Query: 336 KLEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAER 395
KLEEE+ R K + +K R ++ GK R S S D + +DI E
Sbjct: 635 KLEEERRHRQKL-----EKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEE 689
Query: 396 EYDFC---DPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTE 452
+ D + P + ++ D + S ++ H E S E +
Sbjct: 690 MPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKH--RNTETSKSPE-----KD 742
Query: 453 MPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDL 512
+P E K + +D+ + E+ KA++ + + P A + P
Sbjct: 743 VPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPA-PAPVPS 801
Query: 513 AEGCSQDDQTPSQSYIDDS 531
+ C +D +T +Q DD+
Sbjct: 802 TDEC-EDAKTEAQGEEDDA 819
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 43.1 bits (100), Expect = 0.001
Identities = 74/423 (17%), Positives = 152/423 (35%), Gaps = 8/423 (1%)
Query: 457 EPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGC 516
+ S S S S+S S + S+ + + S S D+S G SS + +
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Query: 517 SQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPG 576
S + + S DS+ + S + S++S + S S + S++ E
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927
Query: 577 KPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKL 636
++ S NS + ++D + SS++ ++ S + D ++ ++
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDS----SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 637 SPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKE 696
SD S + S + S ++ +N + S D
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS-SNSSDSSNSSDSSDSSDSSDS 1042
Query: 697 IFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPA 756
S D+ S S +S S S + + + + S + ++ + +
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 757 SQRQQESGGNQEA-SFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQ 815
S S + + S D N SD DS + + ++ + N D + D
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSD--SSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160
Query: 816 RKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIV 875
+ + + + +DSS++ ++ S+ SS + DS +S + S +S++S
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 876 ESN 878
+S+
Sbjct: 1221 DSS 1223
Score = 41.6 bits (96), Expect = 0.003
Identities = 99/536 (18%), Positives = 182/536 (33%), Gaps = 56/536 (10%)
Query: 354 SGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPREGCFI 413
SG+ K + S S S + S D SD + + D D
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD------------ 589
Query: 414 IEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSH 473
D+ S+ + S + + S + + +++ E S SK S S+
Sbjct: 590 ---SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN 646
Query: 474 TQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQD--DQTPSQSYIDDS 531
+ D S N S+ + S S D+S + S + + S D D + S D S
Sbjct: 647 SSDS-SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 705
Query: 532 TLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSC 591
+ + + S++S + S S S + + +S S NS
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765
Query: 592 PTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPV 651
+ ++D + SS++ ++ S N D + + S S S +
Sbjct: 766 DSSDSSDS----SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Query: 652 GHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTL 711
+ S + S ++ + G++ S ++ S D+ S+
Sbjct: 822 NSSDSSNSSDSSDSSNSSDSSDSSDSS-----DGSDSDSSNRSDSSNSSDSS----DSSD 872
Query: 712 SVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASF 771
S NS S S + E S + ++ + +S N S
Sbjct: 873 SSNSSDSSDSS-----------------DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 772 DYYNVSDDDDSEEGA-NKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKET 830
D N SD +S + N N+ + N D + D + + + +
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS---DSSNSSDSSNSSDSSNS---SDSS 969
Query: 831 DSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALS 886
DS+S+ + S DS DSS + DS +S + S +S++S +S+ + + S
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Score = 40.8 bits (94), Expect = 0.006
Identities = 80/467 (17%), Positives = 162/467 (34%), Gaps = 22/467 (4%)
Query: 459 SRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQ 518
S SS S S+S + S ++ S+ + S NS +S D ++ S
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD--SS 620
Query: 519 DDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKP 578
D ++ S DS+ +++ S S+ + S S + S + +
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 579 PESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSP 638
+S S +S + +++ ++S + N D D+ ++ +
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Query: 639 SDRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIF 698
SD S + S + S ++ + + + SS D
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS-DSSDSSN 799
Query: 699 SKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQ 758
S D+ S S +S SS S S+ +D+ + S + ++ +
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS----SNSSDSSDSSDSSDGSDSDS 855
Query: 759 RQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKF 818
+ N S D + S+ DS + ++ N E N D + D
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN--ESSNSSDSS------DSSNSSDSDSSD 907
Query: 819 EKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESN 878
N +DSS + ++ S+ + +S + DS +S + S +SN+S S+
Sbjct: 908 SSN-------SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 879 RRQNPALSPAHGGAGPAFNFRASAEPPTNEAEKLQKPSNCLQASVTS 925
N + S + + + +S ++++ S+ +S +S
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Score = 39.3 bits (90), Expect = 0.017
Identities = 75/456 (16%), Positives = 158/456 (34%), Gaps = 23/456 (5%)
Query: 472 SHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDS 531
S++ D ++ + S D+S SS D + D + S D S
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Query: 532 TLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSC 591
+++ S + SS S SK SS + + +S S NS
Sbjct: 618 DSSDSKSDSSKSESDSSDS-----------DSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 592 PTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPV 651
+ ++D ++S S + + D+ +E SD SS
Sbjct: 667 DSSDSSDSSDSSSSSDS------SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 652 GHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTL 711
+ +S + S ++ + S D S D+ S
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSS----DSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 712 SVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASF 771
S +S S S + + + S + ++ + ++ + + S
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 772 DYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETD 831
+ + SD DS +G++ ++ + + + D + N + + +D
Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896
Query: 832 SSSNQRATHSARLDSMDS--SSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAH 889
SS++ + S +S DS SS + DS +S + S +S++S+ +S+ + + S
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 890 GGAGPAFNFRASAEPPTNEAEKLQKPSNCLQASVTS 925
+ + N S++ ++++ S+ +S +S
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Score = 30.8 bits (68), Expect = 6.1
Identities = 75/453 (16%), Positives = 140/453 (30%), Gaps = 12/453 (2%)
Query: 345 SKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHL----DIPAEREYDFC 400
S GS + S RS S + S S+S D ++ S+ D + D
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906
Query: 401 DPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSR 460
D ++ N+N +S + + S + + + S
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS--NSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 461 GSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDD 520
S S + S S S + S+ + + S S D+S +S D + +
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDSSDSSNSSDSSN 1023
Query: 521 QTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPE 580
+ S + D S + S S+ S S + S + + E
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 581 SLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSD 640
S S NS + ++D ++S + + S + + D+ ++ + SD
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 641 RQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSK 700
S + + S + S ++ +N S D S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 701 DTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQR- 759
D+ S S +S S S + + + S + ++ + +S
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDST 1262
Query: 760 ---QQESGGNQEASFDYYNVSDDDDSEEGANKN 789
ES ++ N SD D EG++ N
Sbjct: 1263 SDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 43.1 bits (100), Expect = 0.001
Identities = 77/392 (19%), Positives = 144/392 (36%), Gaps = 70/392 (17%)
Query: 517 SQDDQTPSQSYIDDSTLRPAQTVSL---QRAHI---SSTSYKEVCIPEIVSGSKEPSSAC 570
S D +P+ + ++ L+P +T+S Q + + S S K + S++ SS
Sbjct: 2231 SLDLSSPNMANTVNAALKPLETLSRIVNQPSSLFGSKSASSKNKSEQDAQGASQDSSS-- 2288
Query: 571 SLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLA 630
+ +PG+P E+ + + T+ A D +++V+ A P
Sbjct: 2289 NQQDPGEPGEAEVQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQP-------------- 2334
Query: 631 EGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSS 690
+ LS + QV + + + E G G N ++ E
Sbjct: 2335 ---EVLSSQEMQVENELEDLIDELLERDGGSG--------------NSTIIVSRSGE--- 2374
Query: 691 LDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPK---TPADTLPGRCEKLEPSLG 747
D+ +E D L ++ + + S+++L + T + G E + S
Sbjct: 2375 -DESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQD 2433
Query: 748 TSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLE 807
+ Q++ G + D+DD ++G+ +E+ + +
Sbjct: 2434 EEEEEEEDEEDDQEDDEGEE---------GDEDDDDDGSEMELDEDYPDMNASPLVRFER 2484
Query: 808 REKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFN-------- 859
++E DL +F+ N+ A S N TH + D SS+T+ SG +
Sbjct: 2485 FDREDDLIIEFD-NMFSSATDIPPSPGNIPTTHPLMVRHADHSSLTLGSGSSTTRLTQGI 2543
Query: 860 --SPRTRESLASNTSSIVE----SNRRQNPAL 885
S RT L +NT + NR+ NP L
Sbjct: 2544 GRSQRTLRQLTANTGHTIHVHYPGNRQPNPPL 2575
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 28/160 (17%)
Query: 751 AQAMPASQRQQESGGNQEASFDYYNVSD---------------DDDSEEGANKNTEEEKN 795
A+A P ++RQ++ G N+E D + D D E +K + ++
Sbjct: 222 ARARPDNERQKDRG-NRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRR 280
Query: 796 REDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVD 855
R G W L+REK R+ + P++ +SS + + + DS + T
Sbjct: 281 RVKNGEHSWDLDREKNREHDK----------PEKKSASSGEMSKKLSDGTFKDSKAETET 330
Query: 856 SGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAGPA 895
S R +SL + TS N + + S A G AGPA
Sbjct: 331 E--ISTRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPA 368
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 43.1 bits (100), Expect = 0.001
Identities = 82/387 (21%), Positives = 135/387 (34%), Gaps = 64/387 (16%)
Query: 462 SSHSKVHR---SHSHTQDRR------SRNERSNKAKERSRSMDNSKGPLGASSLGTPEDL 512
S ++HR S S +++R S NE N+ S S + K P S E+L
Sbjct: 82 SESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLP---GSDSENEEL 138
Query: 513 AEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKE--PSSAC 570
G + D + + ++ LQ++ S + ++ P+I E P
Sbjct: 139 LNGHASDSENED---VGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQA 195
Query: 571 SLLEPGKPPESLPSYGELNSCPTKTATDDY------FQCNTSSETVLTAPSPLGKNKEDH 624
S E +PP+ S E P +D Q + S L P ED
Sbjct: 196 SDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDP 255
Query: 625 DTLTLAEGVK------KLSPSDRQVPHSSREPVGHKEESPK---------GPGGGPAASG 669
++ ++S S+ + P ++ EE PK GP GPA+
Sbjct: 256 PRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDS 315
Query: 670 GVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFK--PLHSTLSVN--SYHKSSLSLLK 725
+ +H S D +E +DT + HS ++ +H S S +
Sbjct: 316 ETEDAS------RHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSD-SEEE 368
Query: 726 SHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDD----- 780
H K D+ E E + A + S+ ++++ + + SD D
Sbjct: 369 EHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDK 428
Query: 781 ----------DSEEGANKNTEEEKNRE 797
DSEE A K ++KN E
Sbjct: 429 SGKREKTIASDSEEEAGKELSDKKNEE 455
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 42.4 bits (98), Expect = 0.002
Identities = 63/300 (21%), Positives = 109/300 (36%), Gaps = 31/300 (10%)
Query: 612 TAPSPLGKNKEDH------DTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGP 665
+A SP G+ H D L + LS R + SR E P P G P
Sbjct: 33 SARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSR-SRSRERPSAPRGIP 91
Query: 666 AASGGVAEGIANGRLVQHHGAE---PSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLS 722
AS + + G + +G++ PS LDK +E + + + LS
Sbjct: 92 FASA--SSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLS 149
Query: 723 LLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASF---------DY 773
P + T E EP T++A ++++ S + + +
Sbjct: 150 PKNPEPDSDEHT---PVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKH 206
Query: 774 YNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKE-TDS 832
S+D DS+ + ++ +E N+ + +++K R +K++K + + KE +DS
Sbjct: 207 KKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHR--SKKYKKKRSKKSRKESSDS 264
Query: 833 SSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGA 892
SS + D + S P ++L S + AL P G A
Sbjct: 265 SSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGH----ALLPGEGAA 320
Score = 35.0 bits (79), Expect = 0.32
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 17/82 (20%)
Query: 437 TPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRR----------------SR 480
+P+ + SG +RR+ P+PS+ + + RS SH+ R SR
Sbjct: 9 SPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSR 68
Query: 481 NERSNKAKERSRSMDNSKGPLG 502
N+ S +++ RSRS + P G
Sbjct: 69 NQ-SYRSRSRSRSRERPSAPRG 89
>gi|148727255 microtubule associated serine/threonine kinase family
member 4 isoform a [Homo sapiens]
Length = 2434
Score = 41.6 bits (96), Expect = 0.003
Identities = 80/360 (22%), Positives = 130/360 (36%), Gaps = 50/360 (13%)
Query: 552 KEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVL 611
K++ P PS A G+ P + PS E +S P +SS
Sbjct: 1952 KDLSSPAARQHCSSPSHAS-----GREPGAKPSTAEPSSSPQDPPKPVAAHSESSSHKPR 2006
Query: 612 TAPSPLGKNKEDHDTLTLAE------GVKKLSPSDRQVPHSSREPVGHKEES----PKGP 661
P P G K H +L+ K P+ + + SSRE GH + P P
Sbjct: 2007 PGPDP-GPPKTKHPDRSLSSQKPSVGATKGKEPATQSLGGSSREGKGHSKSGPDVFPATP 2065
Query: 662 GGGPAASGGVAEGIANGRLVQHHG-------AEPSSLDKRKEIFSKDT-LFKPLHSTLSV 713
G AS G+ +G + H +P+S + E+ K L +P H S
Sbjct: 2066 GSQNKASDGIGQGEGGPSVPLHTDRAPLDAKPQPTSGGRPLEVLEKPVHLPRPGHPGPSE 2125
Query: 714 NSYHKSSL-----SLLKSHPK-TPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQ 767
+ K S +L HPK + P C++ + + T + + PA+ + + G +
Sbjct: 2126 PADQKLSAVGEKQTLSPKHPKPSTVKDCPTLCKQTD-NRQTDKSPSQPAANTDRRAEG-K 2183
Query: 768 EASFDYYNVSDDDDSEEGA----NKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLT 823
+ + Y ++ D E G ++N + R G + E + +K
Sbjct: 2184 KCTEALYAPAEGDKLEAGLSFVHSENRLKGAERPAAGVGKGFPEARGKGPGPQK------ 2237
Query: 824 LLAPKETDSSSNQRATHSA------RLDSMDSSSITVDSGFNSPRTRESLASNTSSIVES 877
P E D + + + SA R ++ S++ S F R AS SS S
Sbjct: 2238 --PPTEADKPNGMKRSPSATGQSSFRSTALPEKSLSCSSSFPETRAGVREASAASSDTSS 2295
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 41.6 bits (96), Expect = 0.003
Identities = 108/503 (21%), Positives = 166/503 (33%), Gaps = 54/503 (10%)
Query: 435 PMTPEWDVSGELAKRRTEMPFPE-PSRGS--SHSKVHRSHSHTQDRRSRNERSNKAKERS 491
P TP + S + + P PSR S S R S T R S + S K+
Sbjct: 1411 PRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIP 1470
Query: 492 RSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSY 551
R+ S+G S P+ L + ++PS +++ L P + S SS
Sbjct: 1471 RTP--SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSE---SSVDQ 1525
Query: 552 KEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVL 611
K V + S+ SS ++P P+ KT T + + S +
Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV 1585
Query: 612 TAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGV 671
+ S L + + SP + P ++ + SP+ P A +
Sbjct: 1586 DSKSRLSPRRSRSGS----------SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA---L 1632
Query: 672 AEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTP 731
+G + G P S T P H S + S S PKT
Sbjct: 1633 PRRSRSGSSSKGRGPSPEG--------SSSTESSPEHPPKSRTARRGSRSS---PEPKTK 1681
Query: 732 ADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTE 791
+ T P R T A+ S+ S + + + S S E A K+
Sbjct: 1682 SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
Query: 792 EEKNREDVGTMQWLLERE------KERDLQR-----KFEKNLTLLAPKETDSSSNQRATH 840
+ R R K R LQR + EK T + D S + ++T
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTT---RRRDRSGSSQSTS 1798
Query: 841 SARLDSMDSSSITV----DSGFNSPRTRESLASNTSSIVESNRRQNPAL----SPAHGGA 892
R S S +T SG++S +S TSS R + P S +
Sbjct: 1799 RRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858
Query: 893 GPAFNFRASAEPPTNEAEKLQKP 915
P R+ A P T+ + + P
Sbjct: 1859 APWKRSRSRASPATHRRSRSRTP 1881
Score = 40.4 bits (93), Expect = 0.008
Identities = 130/574 (22%), Positives = 210/574 (36%), Gaps = 93/574 (16%)
Query: 343 QRSKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDP----SDGSHLDIPAEREYD 398
+RS++ S A SGRS+ R+ +SR+ ++ S+ S S PA R
Sbjct: 633 RRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS 692
Query: 399 FCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEP 458
+R PR G + + + SH SG ++R+ + +
Sbjct: 693 ----RSRTPRRG----RSRSRSLVRRG-----RSHSRTPQRRGRSGSSSERKNKSRTSQ- 738
Query: 459 SRGSSHSKVHRSHSHTQDRRSRNERSNKAKERS-----RSMDNSKGPLGASSLGTPEDLA 513
R S+S S RRSR+ S ++K +S RS+ S S P
Sbjct: 739 RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSR 798
Query: 514 EGCSQ---DDQTPSQSYIDDSTLRPAQ--TVSLQRAHISSTSYKEVCIPEIVSGSKEPSS 568
G SQ +TP + S+ P Q +++H SS+ + P++ SG+ P
Sbjct: 799 SGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH-----PKVKSGT--PPR 851
Query: 569 ACSLLEPGKPPESLPSYGELNSC-------PTKTATDDYFQCNTSSETVLTAPSPLGKNK 621
S+ P +S+ + SC K+ T C+ SS + + +P +
Sbjct: 852 QGSITSPQANEQSVTP--QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP---PR 906
Query: 622 EDHDTLTLAEGVKKLSPSDRQVPHS-SREPVGHKEESPKGPGGGPAASGGVAEGIANGRL 680
+ + + K S RQ HS S P + S P + S RL
Sbjct: 907 QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS---PCSNVESRL 963
Query: 681 VQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRC- 739
+ + SS S DT KP H S+S +PK A T PG
Sbjct: 964 LPRYSHSGSS--------SPDTKVKP---ETPPRQSHSGSIS---PYPKVKAQTPPGPSL 1009
Query: 740 ---------EKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNT 790
EK + SL S ++ + S E+ Y+ VS S + ++
Sbjct: 1010 SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGES---YFGVS----SLQLKGQSQ 1062
Query: 791 EEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSA-----RLD 845
+R D + + + LQ K + +PK S S+ T A R D
Sbjct: 1063 TSPDHRSDTSSPEVRQSHSESPSLQSKSQ-----TSPKGGRSRSSSPVTELASRSPIRQD 1117
Query: 846 SMD-SSSITVDSGFNSPRTRESLASNTSSIVESN 878
+ S+S + SG + ++R S++ V+SN
Sbjct: 1118 RGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSN 1151
Score = 40.0 bits (92), Expect = 0.010
Identities = 76/331 (22%), Positives = 108/331 (32%), Gaps = 46/331 (13%)
Query: 445 ELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGAS 504
E KR+ P P+ R S K RS S T +SR + + + + S D S+ ++
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Query: 505 SLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIP------- 557
+ T G S + + D P T S QR T+ K+ P
Sbjct: 283 AAKTHTTALAGRSPSPASGRRGEGDAPFSEPG-TTSTQRPSSPETATKQPSSPYEDKDKD 341
Query: 558 --EIVSGSKEPSSACSLLEPGKPPESLPSYGELN-SCPTKTATDDYFQ--CNTSSETVLT 612
E + PS S P +PP P E + P AT Q N SE T
Sbjct: 342 KKEKSATRPSPSPERSSTGP-EPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT 400
Query: 613 APSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGVA 672
K+ E + +E SP Q SR H SP+ P PA
Sbjct: 401 RDRSPPKSPEKLPQSSSSES----SPPSPQPTKVSR----HASSSPESPKPAPA------ 446
Query: 673 EGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPA 732
P S +EI S T H + H + S ++PA
Sbjct: 447 ---------------PGS---HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPA 488
Query: 733 DTLPGRCEKLEPSLGTSAAQAMPASQRQQES 763
GR P+ + P +R + +
Sbjct: 489 TAKRGRSRSRTPTKRGHSRSRSPQWRRSRSA 519
Score = 37.0 bits (84), Expect = 0.085
Identities = 128/631 (20%), Positives = 221/631 (35%), Gaps = 118/631 (18%)
Query: 344 RSKAGSSAHHSGRSK----------KSRTHRKSHGKSRS-------HSKTRVSKGDPSDG 386
RS++ + A SGRS+ +SRT R+ +SRS HS+T +G
Sbjct: 668 RSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727
Query: 387 SHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGEL 446
S + + + I + + + S + +S + S
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS--LSSPRSKAKSRLSLRRSLSGSSPC 785
Query: 447 AKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERS----NKAKERSRSMDNSKGPLG 502
K++++ P P R S S ++ S T RRSR+ S K+K SR +S P
Sbjct: 786 PKQKSQTP---PRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP 842
Query: 503 ASSLGTP----EDLAEGCSQDDQTPSQSYIDDSTLRP---AQTVSLQRAHISSTSYKEVC 555
GTP + ++ TP + +S+ P ++T S SS +
Sbjct: 843 KVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS 902
Query: 556 IPEIVSGSKEPS------SACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSET 609
P S S+ S + S + S PS + S T + C+
Sbjct: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962
Query: 610 VLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGH-KEESPKGPGGGPAAS 668
+L S G + D VK +P RQ S P K ++P GP+ S
Sbjct: 963 LLPRYSHSGSSSPD-------TKVKPETP-PRQSHSGSISPYPKVKAQTPP----GPSLS 1010
Query: 669 GGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHP 728
G P +K SKD+L + +LS+ + KSS
Sbjct: 1011 G---------------SKSPCPQEK-----SKDSLVQSCPGSLSLCAGVKSS-------- 1042
Query: 729 KTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANK 788
T PG E G S+ Q SQ + + + + S+ + +
Sbjct: 1043 -----TPPG-----ESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQT 1092
Query: 789 NTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMD 848
+ + ++R + L R R + +F + L + + S Q + S+ ++D
Sbjct: 1093 SPKGGRSRSSSPVTE-LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQ--SDSSSYPTVD 1149
Query: 849 SSSITVDSGFNSPRTRESLA-------------------------SNTSSIVESNRRQNP 883
S+S+ S + ++E +A SS+V + + P
Sbjct: 1150 SNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTP 1209
Query: 884 ALSPAHGGAGPAFNFRASAEPPTNEAEKLQK 914
+ G+ P + SA P +++ E+L +
Sbjct: 1210 PRERSGAGSSPETKEQNSALPTSSQDEELME 1240
Score = 35.4 bits (80), Expect = 0.25
Identities = 84/407 (20%), Positives = 142/407 (34%), Gaps = 54/407 (13%)
Query: 257 KDSEKQSKKFGLK---LFRLSFKKDKTKQLANFSAQFPPEEWPLRDEDTPATIPREVEME 313
K +E+ FG+ + SF + + A A PP+ + L E + + P + +
Sbjct: 130 KKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKK 189
Query: 314 IIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSRSH 373
++ + R + + E +K+ + K H S K R HR KS+
Sbjct: 190 KKKK------KDRGRRSESSSPRRERKKSSKKKK----HRSESESKKRKHRSPTPKSKRK 239
Query: 374 SKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESH 433
SK + K S PA + R R D S + ++H
Sbjct: 240 SKDKKRK-----RSRSTTPAPKS-------RRAHRSTSADSASSSDTSRSRSRSAAAKTH 287
Query: 434 FPMTPEWDVSGELAKR-RTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSR 492
S +R + PF EP S+ S T ++ + +K K++
Sbjct: 288 TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ---RPSSPETATKQPSSPYEDKDKDKKE 344
Query: 493 SMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYK 552
P +PE + G TP + + +P T L S +
Sbjct: 345 KSATRPSP-------SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL--------SQE 389
Query: 553 EVCIPEIVSGSKEPSSACSLLEPGKPPESLP-SYGELNSCPTKTATDDYFQCNTSSETVL 611
V P S +++ S P K PE LP S +S P+ T ++S E+
Sbjct: 390 PVNPPSEASPTRDRS-------PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK 442
Query: 612 TAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESP 658
AP+P G ++E + T + D+ H+ +G + SP
Sbjct: 443 PAPAP-GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMG-RSRSP 487
Score = 34.3 bits (77), Expect = 0.55
Identities = 27/91 (29%), Positives = 35/91 (38%), Gaps = 15/91 (16%)
Query: 435 PMTPEWDVSGELAKRRTEMPFPEPSRGS-------------SHSKVHR--SHSHTQDRRS 479
P +P+ A E P P P+ GS SH + R SHSHT RR
Sbjct: 422 PPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM 481
Query: 480 RNERSNKAKERSRSMDNSKGPLGASSLGTPE 510
RS +R RS + G S +P+
Sbjct: 482 GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512
Score = 32.3 bits (72), Expect = 2.1
Identities = 41/188 (21%), Positives = 72/188 (38%), Gaps = 15/188 (7%)
Query: 743 EPSLGTSAAQA------MPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNR 796
EP T A Q PA +R+ S + +S + S S + +++ E +
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
Query: 797 EDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDS 856
V L ++ + P E + +R + S+ S SSS + S
Sbjct: 2568 LPVQPEVALKRVPSPTPAPKEAVREGR---PPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 857 GFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAGPAFNFRASAEPPTNE--AEKLQK 914
+S + S +S++SS S+ +PA PA + +PP E + +K
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA----SPKKPPPGERRSRSPRK 2680
Query: 915 PSNCLQAS 922
P + L+ S
Sbjct: 2681 PIDSLRDS 2688
Score = 30.8 bits (68), Expect = 6.1
Identities = 67/345 (19%), Positives = 119/345 (34%), Gaps = 31/345 (8%)
Query: 164 IPDRSQCTSPQPGTITPSASGCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKDCK 223
+P RS+ S G PS G + P H R S+ P + ++ +
Sbjct: 1632 LPRRSRSGSSSKGR-GPSPEGSSSTESSPE-HPPKSRTARRGSRSSPEPKTKSRTPPRRR 1689
Query: 224 DPYCPPSLCQVPPTEKSKSTVNFSYKTETLSKPK-------DSEKQSKKFGLKLFRLSFK 276
P L + + + + S +T + + P+ S + ++K R S
Sbjct: 1690 SSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSAS 1749
Query: 277 KDKTKQLANFSAQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKK 336
+TK + P+ L+ + + R + RR + + ++ R +
Sbjct: 1750 SPRTKTTSRRGRSPSPKPRGLQRSRSRS---RREKTRTTRRRDRSGSSQSTSRRR--QRS 1804
Query: 337 LEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAERE 396
+ R + G S +HS + + R S + R S+T + S P +R
Sbjct: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRS 1864
Query: 397 YDFCDPLT-RVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPF 455
P T R R +I + S T+ + + + +RR+
Sbjct: 1865 RSRASPATHRRSRSRTPLISRRRS----RSRTSPVSRRRSRS-----RTSVTRRRSRSRA 1915
Query: 456 PEPSRGSSHSKV-------HRSHSHTQDRRSRNERSNKAKERSRS 493
SR S S+ RS + T RRSR+ + RSRS
Sbjct: 1916 SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRS 1960
Score = 30.8 bits (68), Expect = 6.1
Identities = 45/211 (21%), Positives = 72/211 (34%), Gaps = 30/211 (14%)
Query: 442 VSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPL 501
V E+A +R P P P R R AK + RS +S
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAV--------------REGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 502 GASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVS 561
+SS + + S + S S S+ P+ +A +P+ S
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA-----------LPKPAS 2664
Query: 562 GSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNK 621
K P P KP +SL L+ P + S ++ S G +
Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRP---SPQPSPRDQQSSSSERGSRR 2721
Query: 622 -EDHDTLTLAEGVKKLSPSDRQVPH-SSREP 650
+ D+ + + ++ +PS R + H SSR P
Sbjct: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
>gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform a
[Homo sapiens]
Length = 745
Score = 41.2 bits (95), Expect = 0.005
Identities = 52/237 (21%), Positives = 82/237 (34%), Gaps = 17/237 (7%)
Query: 474 TQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTP---SQSYIDD 530
T + S+ +SN A+ + D G +S+ P G + TP + S +
Sbjct: 385 TSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLST 444
Query: 531 STLRPAQTVSLQRAHISSTSYK----EVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYG 586
ST R + L+RA + S + + +P + + S+A S P + +S+ +
Sbjct: 445 STNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASV 504
Query: 587 ELNSCPTKTATDDYFQCNTSSETVLTAP--SPLGKNKEDH----DTLTLAEGVKKLSPSD 640
N T+ + S P SP N D GV S
Sbjct: 505 HPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFH 564
Query: 641 ----RQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDK 693
RQV P G SP G G + G + V+ + EP S D+
Sbjct: 565 AGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDR 621
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 41.2 bits (95), Expect = 0.005
Identities = 74/359 (20%), Positives = 132/359 (36%), Gaps = 65/359 (18%)
Query: 467 VHRSHSHTQDRRSRNERSNKAKE--RSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQT-- 522
+ ++ +++ S + KAKE +S SM + P + PEDL +GCS+ D +
Sbjct: 1217 IGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANND--QPEDLIQGCSESDSSVL 1274
Query: 523 -------------PSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSA 569
P +DD ++R +T ++ I + ++V ++ S +EPS +
Sbjct: 1275 RMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVS--DLASRGQEPSKS 1332
Query: 570 CSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNK-----EDH 624
KT +D+F ++ + + + KNK E+
Sbjct: 1333 ------------------------KTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEES 1368
Query: 625 DTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHH 684
DT+ + S + P+ + +G G + S E ++ +Q
Sbjct: 1369 DTIVSSSKSALHSSVPKSTNDRDATPLSRAMDF-EGKLGCDSESNSTLENSSDTVSIQDS 1427
Query: 685 GAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEP 744
E + E S+ F+ + V L LK + T G CE P
Sbjct: 1428 SEEDMIVQNSNESISEQ--FRTREQDVEV-------LEPLKCELVSGEST--GNCEDRLP 1476
Query: 745 SLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQ 803
GT A P+ Q++ E + S D + + D + N+N E EK + T Q
Sbjct: 1477 VKGTEANGKKPSQQKKLEERPVNKCS-DQIKLKNTTDKKN--NENRESEKKGQRTSTFQ 1532
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 41.2 bits (95), Expect = 0.005
Identities = 74/359 (20%), Positives = 132/359 (36%), Gaps = 65/359 (18%)
Query: 467 VHRSHSHTQDRRSRNERSNKAKE--RSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQT-- 522
+ ++ +++ S + KAKE +S SM + P + PEDL +GCS+ D +
Sbjct: 1091 IGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANND--QPEDLIQGCSESDSSVL 1148
Query: 523 -------------PSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSA 569
P +DD ++R +T ++ I + ++V ++ S +EPS +
Sbjct: 1149 RMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVS--DLASRGQEPSKS 1206
Query: 570 CSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNK-----EDH 624
KT +D+F ++ + + + KNK E+
Sbjct: 1207 ------------------------KTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEES 1242
Query: 625 DTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHH 684
DT+ + S + P+ + +G G + S E ++ +Q
Sbjct: 1243 DTIVSSSKSALHSSVPKSTNDRDATPLSRAMDF-EGKLGCDSESNSTLENSSDTVSIQDS 1301
Query: 685 GAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEP 744
E + E S+ F+ + V L LK + T G CE P
Sbjct: 1302 SEEDMIVQNSNESISEQ--FRTREQDVEV-------LEPLKCELVSGEST--GNCEDRLP 1350
Query: 745 SLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQ 803
GT A P+ Q++ E + S D + + D + N+N E EK + T Q
Sbjct: 1351 VKGTEANGKKPSQQKKLEERPVNKCS-DQIKLKNTTDKKN--NENRESEKKGQRTSTFQ 1406
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 40.8 bits (94), Expect = 0.006
Identities = 152/779 (19%), Positives = 248/779 (31%), Gaps = 141/779 (18%)
Query: 102 TTCFPGVPTPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLD 161
TT P PT E T N PT G +T F ++++
Sbjct: 373 TTPSPAEPTEHGE---RTANENTTPSPAEPTEHG-----ERTPFANDKTTSSSAESTEHG 424
Query: 162 ERIPDRSQCTSPQPGTITPSASGCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKD 221
ER P ++ T+P P T + E T P S PT R++ +
Sbjct: 425 ERTPLANENTTPSPAEPTENRERTANENTTP---------------SPAGPTENRETTAN 469
Query: 222 CKDPYCPPSLCQVPPTEKSKSTVNFSYKTETLSKPKDSEKQSKKFGLKLFRLSFKKDKTK 281
K P V PTE ++T N +T P + + + R F +KT
Sbjct: 470 EKTTLSP-----VEPTENRETTAN----EKTTPSPAEPTENGQ-------RTPFANEKTT 513
Query: 282 QLANFSAQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLT------VENVMRHTALMK 335
+ + E PL +E+T + P E R N T EN R +
Sbjct: 514 SSSAEPTEH-GERTPLANENTTPS-PAEPTENRERTANEKTTPSPAEPTENGDRTPLANE 571
Query: 336 KLEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSR---SHSKTRVSKGDPSDGSHLDI- 391
K A+ ++ G + S + + + R ++ T S +P++
Sbjct: 572 KTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTAN 631
Query: 392 ---------PAE-REYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLES--HFPMTPE 439
P E RE + T P E E + S E+ P E
Sbjct: 632 ENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANE 691
Query: 440 WDVSGE-----------LAKRRTEMPFPEPSRG---SSHSKVHRSHSHTQDRRSRNERSN 485
S LA T + EP+ +++ K + + R R N
Sbjct: 692 KTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANEN 751
Query: 486 KAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTP-SQSYIDDSTLRP---AQTVSL 541
++ +N A+ TP LAE +TP + S+ P A+ L
Sbjct: 752 TTPSPAQPTENGDRTPLANEKTTP-SLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPL 810
Query: 542 QRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYF 601
+ +S+ E + ++ + P +P E+ S + P +
Sbjct: 811 ANENTTSSP------AEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENR 864
Query: 602 QCNTSSETVLTAPSPLGKNKEDHDTLT-LAEGVKKLSPSD------------RQVPHSSR 648
+ + T L+ P +H+ +T LA LSP++ + SS
Sbjct: 865 EWTANENTTLSPAEP-----TEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSA 919
Query: 649 EPVGHKEESPKG-----PGGGPAASGGVAEGIANGRLV------QHHG------------ 685
EP H E +P P G E IAN + HG
Sbjct: 920 EPTEHGERTPLANEITTPSRAEPTEHG--ERIANEKATPSPAKPTEHGETTVNEDTTPSS 977
Query: 686 AEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPS 745
AEP+ +R + +++T P ST + + P + P EK PS
Sbjct: 978 AEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPS 1037
Query: 746 ----------LGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEK 794
++ P+ + E G + + +S + +E GA + EK
Sbjct: 1038 PAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEK 1096
Score = 38.5 bits (88), Expect = 0.029
Identities = 143/681 (20%), Positives = 223/681 (32%), Gaps = 128/681 (18%)
Query: 46 PQASRGYMTSGDVSPISMSPISQSQFIPLGEILCLAISAM---NSARKPVTQEALMEHLT 102
P +R + +P P Q P + SA + R P+ E T
Sbjct: 479 PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANEN-----T 533
Query: 103 TCFPGVPTPSQEILRHTLNTLVRERKIYPTPDGYFI------VTP----------QTYFI 146
T P PT ++E T N PT +G TP +T F
Sbjct: 534 TPSPAEPTENRE---RTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFA 590
Query: 147 TPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITPSASGCVRERTLPRNHCDSCHCCREDV 206
++++ +ER P ++ T+P P T + E T P
Sbjct: 591 NEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTP-------------- 636
Query: 207 HSTHAPTLQRKSAKDCKDPYCPPSLCQVPPTEKSKSTVNFSYKTETLSKPKDSEKQSKKF 266
S PT R+ + K P PTE + T N +T S P + + +
Sbjct: 637 -SPAGPTENREMTANEKTTLFP-----AEPTENRERTAN----EKTTSSPAEPTENGQ-- 684
Query: 267 GLKLFRLSFKKDKTKQ-------------LANFSAQFPPEEWPLRDEDTPAT-----IPR 308
R F +KT LAN + P E P + + A P
Sbjct: 685 -----RTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAE-PTENRERTANEKTTPFPA 738
Query: 309 EVEMEIIRRINPDLT------VENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKSRT 362
E R N + T EN R +K A+ ++ G + S +
Sbjct: 739 EPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSS 798
Query: 363 HRKSHGKSR---SHSKTRVSKGDPSDGSH-------LDIPAE----REYDFCDPLTRVPR 408
+ R ++ T S +P++ PAE RE + T P
Sbjct: 799 AEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPA 858
Query: 409 EGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGS-----S 463
E E + S E H MTP LA +T + EP+ +
Sbjct: 859 EPTENREWTANENTTLSPAEPTE-HEEMTP-------LANEKTTLSPAEPTENGERTPFT 910
Query: 464 HSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPE-----DLAEGCSQ 518
+ K S + + R +N+ SR+ G A+ TP + E
Sbjct: 911 NEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVN 970
Query: 519 DDQTPSQSYIDDSTLR-PAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGK 577
+D TPS + ++ R P + + ST + E + PS A EP +
Sbjct: 971 EDTTPSSAEPTENGERTPLANENTTTSPTESTEHGE----RTANEKTTPSPA----EPTE 1022
Query: 578 PPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLS 637
E PS E + P+ ++ + T S T PSP+ K E + TLA LS
Sbjct: 1023 HGERTPSANE-KTIPSPAKPTEHEEM-TPSANENTTPSPV-KPTEHGEKTTLANEKITLS 1079
Query: 638 PSDRQVPHSSREPVGHKEESP 658
P + H ++ +++ +P
Sbjct: 1080 P-EGPTEHGAKTTSANEKITP 1099
Score = 34.7 bits (78), Expect = 0.42
Identities = 99/518 (19%), Positives = 179/518 (34%), Gaps = 78/518 (15%)
Query: 424 HSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNER 483
H E+ P E GE + E P P+ + H + R+ S +
Sbjct: 364 HGERTANENTTPSPAEPTEHGE--RTANENTTPSPAEPTEHGE--RTPFANDKTTSSSAE 419
Query: 484 SNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQS---------YIDDSTLR 534
S + ER+ + + P A P + E + ++ TPS + + +TL
Sbjct: 420 STEHGERTPLANENTTPSPAE----PTENRERTANENTTPSPAGPTENRETTANEKTTLS 475
Query: 535 PAQTVSLQRAHISSTSYKEVCIPEIVSGSKEP----SSACSLLEPGKPPESLPSYGELNS 590
P + + + + P +G + P + S EP + E P E N+
Sbjct: 476 PVEPTENRETTANEKTTPSPAEPT-ENGQRTPFANEKTTSSSAEPTEHGERTPLANE-NT 533
Query: 591 CPTKTATDDYFQCNTSSETVLTAPS---------PLGKNKEDHDTLTLAEGVKKLSPSDR 641
P+ + + T++E +P+ PL K E ++ ++
Sbjct: 534 TPSPAEPTENRE-RTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANE 592
Query: 642 QVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKD 701
+ SS EP H+E +P +AN AEP+ + R+ +++
Sbjct: 593 KTTSSSAEPTEHEERTP----------------LANENTTP-SPAEPT--ENRERTANEN 633
Query: 702 TLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQ 761
T P T + +L + P + EK T+++ A P Q+
Sbjct: 634 TTPSPAGPTENREMTANEKTTLFPAEPTENRERTAN--EK------TTSSPAEPTENGQR 685
Query: 762 ESGGNQEASFDYYNVSDDDDSEEGANKNT-----EEEKNREDVGTMQWL-LEREKERDLQ 815
N++ + ++ + AN+NT E +NRE + E + +
Sbjct: 686 TPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRE 745
Query: 816 RKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIV 875
R +N T P + N T A + S + ++G +P E S+++
Sbjct: 746 RTANENTT---PSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPT 802
Query: 876 ESNRR-----QNPALSPAHGGAGPAFNFRASAEPPTNE 908
E R +N SPA P N +A T +
Sbjct: 803 EHAERTPLANENTTSSPAE----PTENRERTANEKTTQ 836
Score = 33.5 bits (75), Expect = 0.94
Identities = 86/487 (17%), Positives = 164/487 (33%), Gaps = 53/487 (10%)
Query: 447 AKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSL 506
A +T EP+ + + ++ R A E + + GP +
Sbjct: 590 ANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTP--SPAGPTENREM 647
Query: 507 GTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQ-TVSLQRAHISSTSYKEVCIPEIVSGSKE 565
E ++ + ++ + +T PA+ T + QR ++ G +
Sbjct: 648 TANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERT 707
Query: 566 P-SSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPS--------- 615
P ++ + L P +P E+ + P + + T++E +P+
Sbjct: 708 PLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRE-RTANENTTPSPAQPTENGDRT 766
Query: 616 PLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESP---KGPGGGPAASGGVA 672
PL K E K+ ++ + SS EP H E +P + PA
Sbjct: 767 PLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENR 826
Query: 673 EGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPA 732
E AN + Q AEP+ + R+ ++ T P T + + +L + P
Sbjct: 827 ERTANEKTTQ-FPAEPT--ENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHE 883
Query: 733 DTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEE 792
+ P EK T+ + A P ++ N++ + ++ + AN+ T
Sbjct: 884 EMTPLANEK------TTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTP 937
Query: 793 EKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSI 852
+ E +R + T K T+ + D+ SS+
Sbjct: 938 SR-------------AEPTEHGERIANEKATPSPAKPTEHGET-----TVNEDTTPSSAE 979
Query: 853 TVDSGFNSPRTRESLASNTSSIVESNRR-------QNPALSPAHGGAGPAFNFRASAEP- 904
++G +P E+ ++ + E R +PA HG P+ N + P
Sbjct: 980 PTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPA 1039
Query: 905 -PTNEAE 910
PT E
Sbjct: 1040 KPTEHEE 1046
>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
Length = 1439
Score = 40.8 bits (94), Expect = 0.006
Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 25/205 (12%)
Query: 708 HSTLSVNSYHKSSLSLLKSHPKTPADTL-PGRCEKLEPSLGTSAAQAMPASQRQQESGGN 766
+S NSYH S S S P TP ++ P + +LE S S + + +S RQ +
Sbjct: 400 YSNFGNNSYHSSRPSSGSSVPTTPTSSVSPPQEARLERS---SPSGLLTSSFRQHQESLA 456
Query: 767 QEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLA 826
E + EE + EE+N+ + +L +RE++R + + K L LA
Sbjct: 457 AERE------RRRQEREERLQRIEREERNK---FSRDYLDKREEQRQAREERYKYLEQLA 507
Query: 827 PKETDSSSNQRATHSARLD-SMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPAL 885
+E + R+ R D S+D SP LA + S S+ ++ AL
Sbjct: 508 AEEHEKELRSRSVSRGRADLSLD---------LTSPAAPACLAPLSHSPSSSDSQE--AL 556
Query: 886 SPAHGGAGPAFNFRASAEPPTNEAE 910
+ + G + +ASA P E+E
Sbjct: 557 TVSASSPGTPHHPQASAGDPEPESE 581
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 40.8 bits (94), Expect = 0.006
Identities = 99/442 (22%), Positives = 142/442 (32%), Gaps = 112/442 (25%)
Query: 454 PFPEPSRGS---SHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPE 510
PFP PS G+ +H V H H Q ++ + ++ + +++ + + GP + P
Sbjct: 461 PFP-PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP- 518
Query: 511 DLAEGCSQDDQTPSQSYIDDSTLR--PAQTVSLQRAHISSTSYKEVCI--PEIVSGSKEP 566
EG S P +LR P L H S SY + P + S S
Sbjct: 519 --LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH-SQVSYSQAGPNGPPVSSSSNSS 575
Query: 567 SSA------CSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKN 620
SS CS P + P+ P P T T +T TV ++P+
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQGAP----YPFPPVPTVTTSSATLSTVIATVASSPA----- 626
Query: 621 KEDHDTLTLAEGVKKLSPSDRQVPHSSR--EPVGHKEESPKG--PGGGPAASGGVAEGIA 676
G K SP P+ R P +K +P G PG P+ G G
Sbjct: 627 -----------GYKTASPPG-PPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPG-- 672
Query: 677 NGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLP 736
+ G P + FKP T+ + S L S P PA
Sbjct: 673 ------YRGTSPP---------AGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPAS 717
Query: 737 GRCEKLEPSLGTSAAQAMPASQ----------------------------------RQQE 762
G P L + + PA + + +
Sbjct: 718 G------PPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLD 771
Query: 763 SGGNQEASFDYYNVSDD------------DDSEEGANKNTEEEKNREDVGTMQWLLEREK 810
G N A D Y V + + A + EEK RE + EREK
Sbjct: 772 RGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREK 831
Query: 811 ERDLQRKFEKNLTLLAPKETDS 832
ER+L+R + AP E S
Sbjct: 832 ERELERSVKLAQEGRAPVECPS 853
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 40.8 bits (94), Expect = 0.006
Identities = 99/442 (22%), Positives = 142/442 (32%), Gaps = 112/442 (25%)
Query: 454 PFPEPSRGS---SHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPE 510
PFP PS G+ +H V H H Q ++ + ++ + +++ + + GP + P
Sbjct: 461 PFP-PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP- 518
Query: 511 DLAEGCSQDDQTPSQSYIDDSTLR--PAQTVSLQRAHISSTSYKEVCI--PEIVSGSKEP 566
EG S P +LR P L H S SY + P + S S
Sbjct: 519 --LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH-SQVSYSQAGPNGPPVSSSSNSS 575
Query: 567 SSA------CSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKN 620
SS CS P + P+ P P T T +T TV ++P+
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQGAP----YPFPPVPTVTTSSATLSTVIATVASSPA----- 626
Query: 621 KEDHDTLTLAEGVKKLSPSDRQVPHSSR--EPVGHKEESPKG--PGGGPAASGGVAEGIA 676
G K SP P+ R P +K +P G PG P+ G G
Sbjct: 627 -----------GYKTASPPG-PPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPG-- 672
Query: 677 NGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLP 736
+ G P + FKP T+ + S L S P PA
Sbjct: 673 ------YRGTSPP---------AGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPAS 717
Query: 737 GRCEKLEPSLGTSAAQAMPASQ----------------------------------RQQE 762
G P L + + PA + + +
Sbjct: 718 G------PPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLD 771
Query: 763 SGGNQEASFDYYNVSDD------------DDSEEGANKNTEEEKNREDVGTMQWLLEREK 810
G N A D Y V + + A + EEK RE + EREK
Sbjct: 772 RGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREK 831
Query: 811 ERDLQRKFEKNLTLLAPKETDS 832
ER+L+R + AP E S
Sbjct: 832 ERELERSVKLAQEGRAPVECPS 853
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,974,127
Number of Sequences: 37866
Number of extensions: 2152673
Number of successful extensions: 10568
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 248
Number of HSP's that attempted gapping in prelim test: 9132
Number of HSP's gapped (non-prelim): 1366
length of query: 926
length of database: 18,247,518
effective HSP length: 112
effective length of query: 814
effective length of database: 14,006,526
effective search space: 11401312164
effective search space used: 11401312164
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.