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Search of human proteins with 55741655
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55741655 anoctamin 8 [Homo sapiens]
(1232 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55741655 anoctamin 8 [Homo sapiens] 2516 0.0
gi|94536803 transmembrane protein 16K [Homo sapiens] 229 2e-59
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 121 5e-27
gi|218156307 anoctamin 6 isoform c [Homo sapiens] 117 7e-26
gi|218156305 anoctamin 6 isoform c [Homo sapiens] 117 7e-26
gi|218156303 anoctamin 6 isoform b [Homo sapiens] 117 7e-26
gi|218156299 anoctamin 6 isoform a [Homo sapiens] 117 7e-26
gi|218084958 anoctamin 4 [Homo sapiens] 114 6e-25
gi|218081589 anoctamin 5 isoform b [Homo sapiens] 110 6e-24
gi|47106048 anoctamin 5 isoform a [Homo sapiens] 110 6e-24
gi|156766084 transmembrane protein 16C [Homo sapiens] 107 5e-23
gi|209862785 anoctamin 2 [Homo sapiens] 102 3e-21
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 90 1e-17
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 89 3e-17
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 70 2e-11
gi|30039694 zinc finger protein 598 [Homo sapiens] 66 2e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 2e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 65 4e-10
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 65 5e-10
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 65 5e-10
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 64 7e-10
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 64 7e-10
gi|33286446 opioid growth factor receptor [Homo sapiens] 64 1e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 3e-09
gi|55750053 atrophin-1 [Homo sapiens] 62 4e-09
gi|55750041 atrophin-1 [Homo sapiens] 62 4e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 62 4e-09
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 61 6e-09
gi|33356148 formin-like 1 [Homo sapiens] 61 6e-09
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 61 8e-09
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 2516 bits (6521), Expect = 0.0
Identities = 1232/1232 (100%), Positives = 1232/1232 (100%)
Query: 1 MAEAASGAGGTSLEGERGKRPPPEGEPAAPASGVLDKLFGKRLLQAGRYLVSHKAWMKTV 60
MAEAASGAGGTSLEGERGKRPPPEGEPAAPASGVLDKLFGKRLLQAGRYLVSHKAWMKTV
Sbjct: 1 MAEAASGAGGTSLEGERGKRPPPEGEPAAPASGVLDKLFGKRLLQAGRYLVSHKAWMKTV 60
Query: 61 PTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPELIVQVRHHRHTRAYAFFVTATYESLLR 120
PTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPELIVQVRHHRHTRAYAFFVTATYESLLR
Sbjct: 61 PTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPELIVQVRHHRHTRAYAFFVTATYESLLR 120
Query: 121 GADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQ 180
GADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQ
Sbjct: 121 GADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQ 180
Query: 181 GEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDDICDY 240
GEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDDICDY
Sbjct: 181 GEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDDICDY 240
Query: 241 FGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVSCVVFALFNVIWSTLFLE 300
FGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVSCVVFALFNVIWSTLFLE
Sbjct: 241 FGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVSCVVFALFNVIWSTLFLE 300
Query: 301 EWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPITRAEEFYYPPWKRLLFQLLVS 360
EWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPITRAEEFYYPPWKRLLFQLLVS
Sbjct: 301 EWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPITRAEEFYYPPWKRLLFQLLVS 360
Query: 361 LPLCLACLVCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLALLVSVSAEGYKKLAIW 420
LPLCLACLVCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLALLVSVSAEGYKKLAIW
Sbjct: 361 LPLCLACLVCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLALLVSVSAEGYKKLAIW 420
Query: 421 LNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKEMLATLLITRQFL 480
LNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKEMLATLLITRQFL
Sbjct: 421 LNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKEMLATLLITRQFL 480
Query: 481 QNVREVLQPHLYRRLGRGELGLRAVWELARALLGLLSLRRPAPRRLEPQADEGGGGGSGG 540
QNVREVLQPHLYRRLGRGELGLRAVWELARALLGLLSLRRPAPRRLEPQADEGGGGGSGG
Sbjct: 481 QNVREVLQPHLYRRLGRGELGLRAVWELARALLGLLSLRRPAPRRLEPQADEGGGGGSGG 540
Query: 541 GGRRCLSGGCGAPEEEEEAALVERRRAGEGGEEGDGPPGGKEEDEDDEEEEDEEEEEDEE 600
GGRRCLSGGCGAPEEEEEAALVERRRAGEGGEEGDGPPGGKEEDEDDEEEEDEEEEEDEE
Sbjct: 541 GGRRCLSGGCGAPEEEEEAALVERRRAGEGGEEGDGPPGGKEEDEDDEEEEDEEEEEDEE 600
Query: 601 EGEEGGLLDCGLRLKKVSFAERGAGRRRPGPSPEALLEEGSPTMVEKGLEPGVFTLAEED 660
EGEEGGLLDCGLRLKKVSFAERGAGRRRPGPSPEALLEEGSPTMVEKGLEPGVFTLAEED
Sbjct: 601 EGEEGGLLDCGLRLKKVSFAERGAGRRRPGPSPEALLEEGSPTMVEKGLEPGVFTLAEED 660
Query: 661 DEAEGAPGSPEREPPAILFRRAGGEGRDQGPDGGPDPEPGSNSDSTRRQRRQNRSSWIDP 720
DEAEGAPGSPEREPPAILFRRAGGEGRDQGPDGGPDPEPGSNSDSTRRQRRQNRSSWIDP
Sbjct: 661 DEAEGAPGSPEREPPAILFRRAGGEGRDQGPDGGPDPEPGSNSDSTRRQRRQNRSSWIDP 720
Query: 721 PEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEI 780
PEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEI
Sbjct: 721 PEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEI 780
Query: 781 RSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLIGQCGQLQRLFPWLSPE 840
RSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLIGQCGQLQRLFPWLSPE
Sbjct: 781 RSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLIGQCGQLQRLFPWLSPE 840
Query: 841 AAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQ 900
AAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQ
Sbjct: 841 AAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQ 900
Query: 901 QRRRREEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKASAKAKGSTAGGHGP 960
QRRRREEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKASAKAKGSTAGGHGP
Sbjct: 901 QRRRREEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKASAKAKGSTAGGHGP 960
Query: 961 ERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGSDTR 1020
ERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGSDTR
Sbjct: 961 ERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGSDTR 1020
Query: 1021 LPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPS 1080
LPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPS
Sbjct: 1021 LPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPS 1080
Query: 1081 SGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPR 1140
SGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPR
Sbjct: 1081 SGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPR 1140
Query: 1141 PPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPP 1200
PPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPP
Sbjct: 1141 PPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPP 1200
Query: 1201 PLPPTSDPLETPAPSPSPSPSPQAVCWPSGWH 1232
PLPPTSDPLETPAPSPSPSPSPQAVCWPSGWH
Sbjct: 1201 PLPPTSDPLETPAPSPSPSPSPQAVCWPSGWH 1232
>gi|94536803 transmembrane protein 16K [Homo sapiens]
Length = 660
Score = 229 bits (583), Expect = 2e-59
Identities = 146/396 (36%), Positives = 214/396 (54%), Gaps = 18/396 (4%)
Query: 109 FFVTATYESLLRGADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELR-FFTSQERQS 167
+ V A+ +L GA+ +GL VK R F+ ++ + F T E Q
Sbjct: 70 YLVGASKIRMLLGAEAVGL---VKECNDNTMRAFTYRTRQNFKGFDDNNDDFLTMAECQF 126
Query: 168 IIRFWLQNLRAKQGEALHN---VRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSW 224
II+ L+NLRAK + + + + ++ L GI+ QVFP+H+ L +L +W
Sbjct: 127 IIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLTSGIVIQVFPLHDSEALKKLEDTW 186
Query: 225 -VQAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEADQTSRDVS 283
+ + QP+D I YFG IA+YF +L ++T A++ AV G Y F D
Sbjct: 187 YTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWEDYDKY--- 243
Query: 284 CVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPITRAE 343
V+FA FN+IWST+ LE WKR A + Y+WGTL + EEPRP F GV I+ IT E
Sbjct: 244 -VIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRK-FEEPRPGFHGVLGINSITGKE 301
Query: 344 EFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQELVLSV-----KGLPRLARFL 398
E YP +KR L LVSLP CL +M+ F ++ L + + ++
Sbjct: 302 EPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYV 361
Query: 399 PKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGF 458
P ++ A+++ + Y+ A +L EN+RLESAY+ HLI+KV++F F+N + SLFYI F
Sbjct: 362 PSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAF 421
Query: 459 YLKDMERLKEMLATLLITRQFLQNVREVLQPHLYRR 494
LKDM+ L++ LATLLIT Q L + E P+ +R
Sbjct: 422 VLKDMKLLRQSLATLLITSQILNQIMESFLPYWLQR 457
Score = 136 bits (343), Expect = 1e-31
Identities = 71/160 (44%), Positives = 99/160 (61%), Gaps = 1/160 (0%)
Query: 731 QAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTG 790
Q LE M Y TF DY E+F+QFGYV LFS +PLAA A++NN E+ SDA K+C
Sbjct: 481 QVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRV 540
Query: 791 LQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLIGQCGQLQRLFPWLSPEAAIVSVVVLE 850
+RPF + +IG WQ E M V+++V NC LIG Q+ +FP S I+ VV +E
Sbjct: 541 FKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMSPQVNAVFP-ESKADLILIVVAVE 599
Query: 851 HFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHE 890
H L LK+++ AIPD P + ++A+LE++ EA K+ +
Sbjct: 600 HALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQ 639
>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
sapiens]
Length = 933
Score = 121 bits (303), Expect = 5e-27
Identities = 115/430 (26%), Positives = 179/430 (41%), Gaps = 110/430 (25%)
Query: 159 FFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHE----- 213
FFTS +R I L + AK L I +L A G++ FP+H+
Sbjct: 249 FFTSTKRHQI----LFEILAKTPYGHEKKNLLG----IHQLLAEGVLSAAFPLHDGPFKT 300
Query: 214 -------QRILNR--LMKSWVQAVCEN--QPLDDICDYFGVKIAMYFAWLGFYTSAMVYP 262
R+ R L + W + N QPLD + YFG K+A+YFAWLGFYT ++
Sbjct: 301 PPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPA 360
Query: 263 AVFGSVLY-----------------------------------------TFTEADQTSRD 281
AV G++++ +A +
Sbjct: 361 AVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDH 420
Query: 282 VSCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRG---VRRISP 338
V F+LF +W+ L LE WKR+ A LAY+W D + E PRPQF + +P
Sbjct: 421 GGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE-DTEERPRPQFAASAPMTAPNP 479
Query: 339 ITRAEEFYYPPWKRLLFQL------LVSLPLCLACLVCVFLLMLGCFQLQELVLSVKG-- 390
IT +E Y+P R L +V + + + CLV + L + +V+S G
Sbjct: 480 ITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYR----AIMAIVVSRSGNT 535
Query: 391 -----LPRLARFLPKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLIIKVVLFQ 445
R+A V+ + + + ++ Y LA L E +R ++ +E +KV +FQ
Sbjct: 536 LLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQ 595
Query: 446 FVNSYLSLFYIGFY----------------LKDME--------RLKEMLATLLITRQFLQ 481
FVN Y S YI F+ +++ E L + L +++ +Q +
Sbjct: 596 FVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVIN 655
Query: 482 NVREVLQPHL 491
N++EVL P L
Sbjct: 656 NMQEVLIPKL 665
Score = 73.6 bits (179), Expect = 1e-12
Identities = 35/83 (42%), Positives = 52/83 (62%)
Query: 742 EDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVES 801
E F +Y EM +QFG+V +F +A PLA L AL+NN +EIR DA K +RP +R +
Sbjct: 702 EGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQD 761
Query: 802 IGQWQKVMEAMGVLAIVVNCYLI 824
IG W ++ + LA++ N +L+
Sbjct: 762 IGIWFHILAGLTHLAVISNAFLL 784
>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 117 bits (293), Expect = 7e-26
Identities = 99/380 (26%), Positives = 170/380 (44%), Gaps = 88/380 (23%)
Query: 159 FFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILN 218
FF R I+ F L ++ + ++NV I L GI + FP+H+ +
Sbjct: 202 FFNPATRSRIVYFILSRVKY---QVINNVSKFG----INRLVNSGIYKAAFPLHDCKFRR 254
Query: 219 R------------LMKSWV--QAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAV 264
+ L + W +++ + QPLD I Y+G KI +YFAWLG+YT ++ AV
Sbjct: 255 QSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAV 314
Query: 265 FGSVLYTFTEADQTS------------------------------RDVSC---------- 284
G + + +Q + +++C
Sbjct: 315 VGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFD 374
Query: 285 ----VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRR---IS 337
+VFA+F +W TLFLE WKRR AEL Y+W T++ E E+ RP++ I+
Sbjct: 375 SFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQE--EQARPEYEARCTHVVIN 432
Query: 338 PITRAEE-FYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQL--QELVLSV 388
IT+ EE + W + + L + + L +A ++ + + L F + +L ++
Sbjct: 433 EITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNI 492
Query: 389 KGLPRLARFL---------PKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLII 439
G + ++L ++ +++ + Y+K+AI + + E R ++ YE L +
Sbjct: 493 NGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTM 552
Query: 440 KVVLFQFVNSYLSLFYIGFY 459
K+ LFQFVN Y S FYI F+
Sbjct: 553 KMFLFQFVNYYSSCFYIAFF 572
Score = 87.0 bits (214), Expect = 1e-16
Identities = 39/80 (48%), Positives = 57/80 (71%)
Query: 745 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQ 804
F +Y EM +QFG+V LF ++FPLA L ALVNN++EIR DA+KL T +R ++ + IG
Sbjct: 664 FYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGA 723
Query: 805 WQKVMEAMGVLAIVVNCYLI 824
WQ +M+ + +LA+V N +I
Sbjct: 724 WQPIMQGIAILAVVTNAMII 743
>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 117 bits (293), Expect = 7e-26
Identities = 99/380 (26%), Positives = 170/380 (44%), Gaps = 88/380 (23%)
Query: 159 FFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILN 218
FF R I+ F L ++ + ++NV I L GI + FP+H+ +
Sbjct: 202 FFNPATRSRIVYFILSRVKY---QVINNVSKFG----INRLVNSGIYKAAFPLHDCKFRR 254
Query: 219 R------------LMKSWV--QAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAV 264
+ L + W +++ + QPLD I Y+G KI +YFAWLG+YT ++ AV
Sbjct: 255 QSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAV 314
Query: 265 FGSVLYTFTEADQTS------------------------------RDVSC---------- 284
G + + +Q + +++C
Sbjct: 315 VGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFD 374
Query: 285 ----VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRR---IS 337
+VFA+F +W TLFLE WKRR AEL Y+W T++ E E+ RP++ I+
Sbjct: 375 SFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQE--EQARPEYEARCTHVVIN 432
Query: 338 PITRAEE-FYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQL--QELVLSV 388
IT+ EE + W + + L + + L +A ++ + + L F + +L ++
Sbjct: 433 EITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNI 492
Query: 389 KGLPRLARFL---------PKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLII 439
G + ++L ++ +++ + Y+K+AI + + E R ++ YE L +
Sbjct: 493 NGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTM 552
Query: 440 KVVLFQFVNSYLSLFYIGFY 459
K+ LFQFVN Y S FYI F+
Sbjct: 553 KMFLFQFVNYYSSCFYIAFF 572
Score = 87.0 bits (214), Expect = 1e-16
Identities = 39/80 (48%), Positives = 57/80 (71%)
Query: 745 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQ 804
F +Y EM +QFG+V LF ++FPLA L ALVNN++EIR DA+KL T +R ++ + IG
Sbjct: 664 FYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGA 723
Query: 805 WQKVMEAMGVLAIVVNCYLI 824
WQ +M+ + +LA+V N +I
Sbjct: 724 WQPIMQGIAILAVVTNAMII 743
>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
Length = 892
Score = 117 bits (293), Expect = 7e-26
Identities = 99/380 (26%), Positives = 170/380 (44%), Gaps = 88/380 (23%)
Query: 159 FFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILN 218
FF R I+ F L ++ + ++NV I L GI + FP+H+ +
Sbjct: 184 FFNPATRSRIVYFILSRVKY---QVINNVSKFG----INRLVNSGIYKAAFPLHDCKFRR 236
Query: 219 R------------LMKSWV--QAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAV 264
+ L + W +++ + QPLD I Y+G KI +YFAWLG+YT ++ AV
Sbjct: 237 QSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAV 296
Query: 265 FGSVLYTFTEADQTS------------------------------RDVSC---------- 284
G + + +Q + +++C
Sbjct: 297 VGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFD 356
Query: 285 ----VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRR---IS 337
+VFA+F +W TLFLE WKRR AEL Y+W T++ E E+ RP++ I+
Sbjct: 357 SFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQE--EQARPEYEARCTHVVIN 414
Query: 338 PITRAEE-FYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQL--QELVLSV 388
IT+ EE + W + + L + + L +A ++ + + L F + +L ++
Sbjct: 415 EITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNI 474
Query: 389 KGLPRLARFL---------PKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLII 439
G + ++L ++ +++ + Y+K+AI + + E R ++ YE L +
Sbjct: 475 NGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTM 534
Query: 440 KVVLFQFVNSYLSLFYIGFY 459
K+ LFQFVN Y S FYI F+
Sbjct: 535 KMFLFQFVNYYSSCFYIAFF 554
Score = 87.0 bits (214), Expect = 1e-16
Identities = 39/80 (48%), Positives = 57/80 (71%)
Query: 745 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQ 804
F +Y EM +QFG+V LF ++FPLA L ALVNN++EIR DA+KL T +R ++ + IG
Sbjct: 646 FYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGA 705
Query: 805 WQKVMEAMGVLAIVVNCYLI 824
WQ +M+ + +LA+V N +I
Sbjct: 706 WQPIMQGIAILAVVTNAMII 725
>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
Length = 910
Score = 117 bits (293), Expect = 7e-26
Identities = 99/380 (26%), Positives = 170/380 (44%), Gaps = 88/380 (23%)
Query: 159 FFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILN 218
FF R I+ F L ++ + ++NV I L GI + FP+H+ +
Sbjct: 202 FFNPATRSRIVYFILSRVKY---QVINNVSKFG----INRLVNSGIYKAAFPLHDCKFRR 254
Query: 219 R------------LMKSWV--QAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAV 264
+ L + W +++ + QPLD I Y+G KI +YFAWLG+YT ++ AV
Sbjct: 255 QSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAV 314
Query: 265 FGSVLYTFTEADQTS------------------------------RDVSC---------- 284
G + + +Q + +++C
Sbjct: 315 VGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFD 374
Query: 285 ----VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRR---IS 337
+VFA+F +W TLFLE WKRR AEL Y+W T++ E E+ RP++ I+
Sbjct: 375 SFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQE--EQARPEYEARCTHVVIN 432
Query: 338 PITRAEE-FYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQL--QELVLSV 388
IT+ EE + W + + L + + L +A ++ + + L F + +L ++
Sbjct: 433 EITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNI 492
Query: 389 KGLPRLARFL---------PKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLII 439
G + ++L ++ +++ + Y+K+AI + + E R ++ YE L +
Sbjct: 493 NGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTM 552
Query: 440 KVVLFQFVNSYLSLFYIGFY 459
K+ LFQFVN Y S FYI F+
Sbjct: 553 KMFLFQFVNYYSSCFYIAFF 572
Score = 87.0 bits (214), Expect = 1e-16
Identities = 39/80 (48%), Positives = 57/80 (71%)
Query: 745 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQ 804
F +Y EM +QFG+V LF ++FPLA L ALVNN++EIR DA+KL T +R ++ + IG
Sbjct: 664 FYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGA 723
Query: 805 WQKVMEAMGVLAIVVNCYLI 824
WQ +M+ + +LA+V N +I
Sbjct: 724 WQPIMQGIAILAVVTNAMII 743
>gi|218084958 anoctamin 4 [Homo sapiens]
Length = 920
Score = 114 bits (285), Expect = 6e-25
Identities = 110/386 (28%), Positives = 165/386 (42%), Gaps = 89/386 (23%)
Query: 148 FIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQ 207
FI N E+ FF + R I+ LQ ++ ++G+ ++ + L G +
Sbjct: 211 FIIHNKET---FFNNATRSRIVHHILQRIKYEEGK---------NKIGLNRLLTNGSYEA 258
Query: 208 VFPVHE-----------------QRILNRLMKSWVQAVCENQPLDDICDYFGVKIAMYFA 250
FP+HE + +L SW + QPLD + YFG KI +YFA
Sbjct: 259 AFPLHEGSYRSKNSIRTHGAENHRHLLYECWASW-GVWYKYQPLDLVRRYFGEKIGLYFA 317
Query: 251 WLGFYTSAMVYPAVFGSV---LYTFTEAD--QTSRDV----------------------- 282
WLG+YT M++PA F + LY T D Q S++V
Sbjct: 318 WLGWYTG-MLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPFMRLSD 376
Query: 283 SCVV--------------FALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRP 328
SCV FA+F +W+T+FLE WKRR A +AY W +D E EE RP
Sbjct: 377 SCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEE-EEIRP 435
Query: 329 QFRGV----RRISPITRAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQEL 384
QF R++PI+ E Y + +L+VS + V + G + +
Sbjct: 436 QFEAKYSKKERMNPISGKPE-PYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVV 494
Query: 385 VLSVKGLPRLARFLPKVMLAL----------LVSVSAEGYKKLAIWLNDMENYRLESAYE 434
+S + A +A ++ + Y+K+A+ L ++E R ES +E
Sbjct: 495 TVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWE 554
Query: 435 KHLIIKVVLFQFVNSYLSLFYIGFYL 460
+K+ LFQFVN S FYI F+L
Sbjct: 555 NSFTLKMFLFQFVNLNSSTFYIAFFL 580
Score = 88.2 bits (217), Expect = 4e-17
Identities = 49/120 (40%), Positives = 71/120 (59%), Gaps = 7/120 (5%)
Query: 706 TRRQRRQNRSSWIDPPEEEHS-PQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSA 764
TRR+ RQ PE + S PQ + M Y F +Y EM +QFG+ +F +A
Sbjct: 641 TRRKVRQEHG-----PERKISFPQWEKDYNLQPMNAY-GLFDEYLEMILQFGFTTIFVAA 694
Query: 765 FPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824
FPLA L AL+NN+IEIR DA+K T +RP R + IG W ++E +G+L+++ N ++I
Sbjct: 695 FPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVI 754
Score = 39.3 bits (90), Expect = 0.023
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
Query: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQH 895
W A + ++V EH +K+LI IPD+P + + M + +Y +E +A+
Sbjct: 843 WHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM----YEAEL 898
Query: 896 RYQQQQRRRREEEERQRHAE 915
Q++R+ R++ + H E
Sbjct: 899 ERLQKERKERKKNGKAHHNE 918
>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
Length = 912
Score = 110 bits (276), Expect = 6e-24
Identities = 101/385 (26%), Positives = 162/385 (42%), Gaps = 85/385 (22%)
Query: 153 VESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVH 212
+E + FF S R I+ + L R G RF I L +P+H
Sbjct: 200 IEDQATFFPSSSRNRIVYYILS--RCPFGIEDGKKRFG-----IERLLNSNTYSSAYPLH 252
Query: 213 EQRILN------------RLMKSWVQA--VCENQPLDDICDYFGVKIAMYFAWLGFYTSA 258
+ + L ++W + + QPLD I +Y+G KI +YF +LGFYT
Sbjct: 253 DGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEM 312
Query: 259 MVYPAVFGSVLYTF----TEADQTSRDV-------------------------------- 282
+ + AV G + + E + +S ++
Sbjct: 313 LFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASK 372
Query: 283 --------SCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVE-EPRPQFRGV 333
S V FA+F IW TLFLE WK+R A L Y+W +D E + + RP+F +
Sbjct: 373 FSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQLRPEFEAM 432
Query: 334 ---RRISPITRAEEFYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQ-LQE 383
R+++ +T+ E Y P + R+ + L + L + +V V + L F
Sbjct: 433 CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFAS 492
Query: 384 LVLSVKGLPRLARFL-PKVMLAL--------LVSVSAEGYKKLAIWLNDMENYRLESAYE 434
+ S L ++ FL P++ +L ++ + Y+K++ W+ ME R YE
Sbjct: 493 FMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYE 552
Query: 435 KHLIIKVVLFQFVNSYLSLFYIGFY 459
L +K+ LFQFVN Y S FY+ F+
Sbjct: 553 SSLTLKMFLFQFVNFYSSCFYVAFF 577
Score = 82.0 bits (201), Expect = 3e-15
Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 9/118 (7%)
Query: 707 RRQRRQNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFP 766
RR+ R N E++H +LES F +Y E QFG+V LF ++FP
Sbjct: 640 RRKARTNSEKLYSRWEQDH-------DLESFGPL--GLFYEYLETVTQFGFVTLFVASFP 690
Query: 767 LAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824
LA L AL+NN++EIR DA+KL T +R + SIG WQ ++ M VL++ N +++
Sbjct: 691 LAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIV 748
Score = 32.7 bits (73), Expect = 2.2
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAK 877
W A + ++V+EH L+K+L+ IPD+P V E + +
Sbjct: 825 WHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKR 866
>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
Length = 913
Score = 110 bits (276), Expect = 6e-24
Identities = 101/385 (26%), Positives = 162/385 (42%), Gaps = 85/385 (22%)
Query: 153 VESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVH 212
+E + FF S R I+ + L R G RF I L +P+H
Sbjct: 201 IEDQATFFPSSSRNRIVYYILS--RCPFGIEDGKKRFG-----IERLLNSNTYSSAYPLH 253
Query: 213 EQRILN------------RLMKSWVQA--VCENQPLDDICDYFGVKIAMYFAWLGFYTSA 258
+ + L ++W + + QPLD I +Y+G KI +YF +LGFYT
Sbjct: 254 DGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEM 313
Query: 259 MVYPAVFGSVLYTF----TEADQTSRDV-------------------------------- 282
+ + AV G + + E + +S ++
Sbjct: 314 LFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASK 373
Query: 283 --------SCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVE-EPRPQFRGV 333
S V FA+F IW TLFLE WK+R A L Y+W +D E + + RP+F +
Sbjct: 374 FSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQLRPEFEAM 433
Query: 334 ---RRISPITRAEEFYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQ-LQE 383
R+++ +T+ E Y P + R+ + L + L + +V V + L F
Sbjct: 434 CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFAS 493
Query: 384 LVLSVKGLPRLARFL-PKVMLAL--------LVSVSAEGYKKLAIWLNDMENYRLESAYE 434
+ S L ++ FL P++ +L ++ + Y+K++ W+ ME R YE
Sbjct: 494 FMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYE 553
Query: 435 KHLIIKVVLFQFVNSYLSLFYIGFY 459
L +K+ LFQFVN Y S FY+ F+
Sbjct: 554 SSLTLKMFLFQFVNFYSSCFYVAFF 578
Score = 82.0 bits (201), Expect = 3e-15
Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 9/118 (7%)
Query: 707 RRQRRQNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFP 766
RR+ R N E++H +LES F +Y E QFG+V LF ++FP
Sbjct: 641 RRKARTNSEKLYSRWEQDH-------DLESFGPL--GLFYEYLETVTQFGFVTLFVASFP 691
Query: 767 LAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824
LA L AL+NN++EIR DA+KL T +R + SIG WQ ++ M VL++ N +++
Sbjct: 692 LAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIV 749
Score = 32.7 bits (73), Expect = 2.2
Identities = 14/42 (33%), Positives = 24/42 (57%)
Query: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAK 877
W A + ++V+EH L+K+L+ IPD+P V E + +
Sbjct: 826 WHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKR 867
>gi|156766084 transmembrane protein 16C [Homo sapiens]
Length = 981
Score = 107 bits (268), Expect = 5e-23
Identities = 103/384 (26%), Positives = 164/384 (42%), Gaps = 85/384 (22%)
Query: 148 FIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQ 207
FI N ++ FF++ R I+ L+ + + G + +R +L G
Sbjct: 291 FIINNKDT---FFSNATRSRIVYHMLERTKYENGISKVGIR---------KLINNGSYIA 338
Query: 208 VFPVHE--------------QRILNRLMKSWVQ--AVCENQPLDDICDYFGVKIAMYFAW 251
FP HE Q + L + W + ++QPLD I YFG KI +YFAW
Sbjct: 339 AFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAW 398
Query: 252 LGFYTSAMVYPAVFGSVLYTF----TEADQTSRDV-----------------------SC 284
LG+YT ++ A+ G ++ + Q S+++ SC
Sbjct: 399 LGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSC 458
Query: 285 --------------VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQF 330
V FA+F IW+T+FLE WKRR + L Y W ++ E E RPQF
Sbjct: 459 IYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWE-EEEETLRPQF 517
Query: 331 RG----VRRISPITRAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQELVL 386
+ ++PIT E + P ++ +LLVS+ + V + G + +V+
Sbjct: 518 EAKYYKMEIVNPITGKPEPHQPSSDKVT-RLLVSVSGIFFMISLVITAVFGVVVYRLVVM 576
Query: 387 S---------VKGLPRLARFLPKVMLALLVSVSAE-GYKKLAIWLNDMENYRLESAYEKH 436
+K + A V + ++ + Y+K+A L ++E R ES +E
Sbjct: 577 EQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENS 636
Query: 437 LIIKVVLFQFVNSYLSLFYIGFYL 460
+K+ LFQFVN S+FYI F+L
Sbjct: 637 FALKMFLFQFVNLNSSIFYIAFFL 660
Score = 83.2 bits (204), Expect = 1e-15
Identities = 37/78 (47%), Positives = 54/78 (69%)
Query: 747 DYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQ 806
+Y EM +QFG+ +F +AFPLA L AL+NN+IEIR DA+K T +RP R IG W
Sbjct: 754 EYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWL 813
Query: 807 KVMEAMGVLAIVVNCYLI 824
++E +G+LA++ N ++I
Sbjct: 814 GILEGIGILAVITNAFVI 831
Score = 33.9 bits (76), Expect = 0.98
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Query: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQH 895
W A + ++V EH +K I IPD+P + + + + +Y +E +E + +H
Sbjct: 907 WHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMM--YEAELEH 964
Query: 896 RYQQQQRRR 904
QQQRR+
Sbjct: 965 --LQQQRRK 971
>gi|209862785 anoctamin 2 [Homo sapiens]
Length = 998
Score = 102 bits (253), Expect = 3e-21
Identities = 94/400 (23%), Positives = 158/400 (39%), Gaps = 92/400 (23%)
Query: 142 FSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAA 201
FS E+ ++Y N++ + FF + R I+ L+ + + L A
Sbjct: 251 FSREKMYLY-NIQEKDTFFDNATRSRIVHEILKRTACSRANNTMGIN---------SLIA 300
Query: 202 RGIIQQVFPVH-------EQRILNR--LMKSWVQ--AVCENQPLDDICDYFGVKIAMYFA 250
I + +P+H E + +R L + W + + QP+D I YFG KI +YFA
Sbjct: 301 NNIYEAAYPLHDGEYDSPEDDMNDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFA 360
Query: 251 WLGFYTSAMVYPAVFGSVLYTF----TEADQTSR---------------DVSC------- 284
WLG YTS ++ +V G +++ + E D SR D SC
Sbjct: 361 WLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSS 420
Query: 285 ----------------VVFALFNVIWSTLFLEEWKRRGAELAYKW---GTLDSPGEAVEE 325
V F++F +W+T+FLE WKR L Y W G + A E
Sbjct: 421 ACGTAQASHLFDNPATVFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEH 480
Query: 326 PRPQFRGVRRISPITRAEEFYYP------------------PWKRLLFQLLVSLPLCLAC 367
RP++ R + + + WK L++ L
Sbjct: 481 SRPEYETKVREKMLKESNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFM 540
Query: 368 LVCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLA--------LLVSVSAEGYKKLAI 419
+ F ++ G + + L + R +V + +++ + E Y +A
Sbjct: 541 IALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILILDEIYGAVAK 600
Query: 420 WLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFY 459
WL +E + E +E+ LI+K L +FVN+Y +FY+ F+
Sbjct: 601 WLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFF 640
Score = 83.6 bits (205), Expect = 1e-15
Identities = 39/103 (37%), Positives = 63/103 (61%)
Query: 722 EEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIR 781
+ HS Q +L+ ++ Y +Y EM +QFG+V LF ++FPLA + AL+NN+IE+R
Sbjct: 715 DSAHSKHPEQWDLDYSLEPYTGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVR 774
Query: 782 SDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824
DA K T L+RP R + IG W ++ +G +++ N ++I
Sbjct: 775 LDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVI 817
>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
Length = 782
Score = 90.1 bits (222), Expect = 1e-17
Identities = 89/354 (25%), Positives = 145/354 (40%), Gaps = 79/354 (22%)
Query: 161 TSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILNRL 220
T+ R I+ F + N + GE +L G+ + FP+H+ RL
Sbjct: 115 TTSLRIRIVNFVVMNNKTSAGETFE------------DLMKDGVFEARFPLHKGE--GRL 160
Query: 221 MKSWVQ--AVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVL----YTFTE 274
K+W + + QP+D+I +YFG K+A+YF WLG+YT +V A+ G ++ ++ E
Sbjct: 161 KKTWARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFE 220
Query: 275 ADQTSRDV-------------------------------------SCVVFALFNVIWSTL 297
A Q S+++ VVFA+F +W+T+
Sbjct: 221 ASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATV 280
Query: 298 FLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPITRAEEFYYPPWKRLLFQL 357
FLE WKR+ A + W L E EE Q + ++ P++ +
Sbjct: 281 FLEIWKRQRARVVLHW-DLYVWDEEQEEMALQ---------LINCPDYKLRPYQHSYLRS 330
Query: 358 LVSLPLCLACLVCVFLLMLGCFQLQELVLSVKGLPRLARFL-PKVMLALLVSVSAEGY-- 414
V L L L ++C+ + M + ++ S FL +V A++V+ + Y
Sbjct: 331 TVILVLTL-LMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVT 389
Query: 415 --------KKLAIWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYL 460
+ +A+ L D E R S E I+ QF + SL YI F L
Sbjct: 390 IIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFIL 443
Score = 74.7 bits (182), Expect = 5e-13
Identities = 34/80 (42%), Positives = 54/80 (67%)
Query: 745 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQ 804
F ++ EM +Q+G+ +F +AFPLA L AL +NL+EIR DA K+ +R ++ + IG
Sbjct: 538 FDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGT 597
Query: 805 WQKVMEAMGVLAIVVNCYLI 824
W +V+E +GVLA++ N +I
Sbjct: 598 WLQVLETIGVLAVIANGMVI 617
Score = 36.2 bits (82), Expect = 0.20
Identities = 18/57 (31%), Positives = 29/57 (50%)
Query: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQ 892
W + V++ EH AL +K + +PDIP V ++ +++YQR H RQ
Sbjct: 696 WFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQ 752
>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
sapiens]
Length = 986
Score = 89.0 bits (219), Expect = 3e-17
Identities = 43/106 (40%), Positives = 67/106 (63%), Gaps = 1/106 (0%)
Query: 720 PPEEEHSPQLTQA-ELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLI 778
PP+ E + Q E++ ++ + +Y EM +QFG+V LF ++FPLA L AL+NN+I
Sbjct: 700 PPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNII 759
Query: 779 EIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824
EIR DA K T L+RP R + IG W ++ +G LA+++N ++I
Sbjct: 760 EIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVI 805
Score = 87.0 bits (214), Expect = 1e-16
Identities = 88/415 (21%), Positives = 158/415 (38%), Gaps = 107/415 (25%)
Query: 142 FSCEEDFIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAA 201
FS E+ +++ + + FF S+ R +I+ L+ + + I L A
Sbjct: 224 FSREKQHLFDLSDKD-SFFDSKTRSTIVYEILKRTTCTKAKYSMG---------ITSLLA 273
Query: 202 RGIIQQVFPVH---------EQRILNRLMKSWVQ--AVCENQPLDDICDYFGVKIAMYFA 250
G+ +P+H E L + W + + QP+D + YFG KI +YFA
Sbjct: 274 NGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFA 333
Query: 251 WLGFYTSAMVYPAVFGSVLYTFTEA------------DQTSRDVSC-------------- 284
WLG YT ++ ++ G +++ + A DQ C
Sbjct: 334 WLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSS 393
Query: 285 ----------------VVFALFNVIWSTLFLEEWKRRGAELAYKWGT--LDSPGEAVEE- 325
V F++F +W+ F+E WKR+ L Y+W + EAV++
Sbjct: 394 ACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDH 453
Query: 326 PRPQFR--------------------------------------GVRRISPITRAEEFYY 347
PR ++ GV+ + +
Sbjct: 454 PRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRF 513
Query: 348 PPWKRLLFQLLVSLPLCLACL--VCVFLLMLGCFQLQELVLSVKGLPRLARFLPKVMLAL 405
P + L ++ + + A + V ++ + + SV+ R+ V++ L
Sbjct: 514 PAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINL 573
Query: 406 LVSVSA-EGYKKLAIWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFY 459
+V + E Y +A WL +E + E ++E+ LI K L +FVNSY +FY+ F+
Sbjct: 574 VVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFF 628
Score = 36.6 bits (83), Expect = 0.15
Identities = 17/74 (22%), Positives = 36/74 (48%)
Query: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQH 895
W A + V+V ++ + + + IPDIP +++++ K + E F R E+ Q
Sbjct: 884 WAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQ 943
Query: 896 RYQQQQRRRREEEE 909
+ + R+++E
Sbjct: 944 LLETWMEKERQKDE 957
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 69.7 bits (169), Expect = 2e-11
Identities = 91/328 (27%), Positives = 117/328 (35%), Gaps = 40/328 (12%)
Query: 918 ARREHDSGG---REEARAEGSGLDPATSSEKASAKAKGSTAGGHGPERPKRPG--SLLAP 972
ARR +GG R +R+ S P +S ++ A+G+ P +PK G +L P
Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 973 NNVMKLKQIIPLQGKFLSS-------GATSSLAAAGAGATTRPPPAQSPTGSDTRLPA-- 1023
K P G SS A S +A + T PPA P+ + T L +
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 1024 -FLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSG 1082
+ FL SP S + PP+A A L P P S A P TPS
Sbjct: 335 LQATHSFLPSPPL---SPLATPPPQAPPALALPPLQA----PPSPPASPPLSPLATPSP- 386
Query: 1083 SSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPP--PMPLPR 1140
Q + L + +P P P P + S APP PL
Sbjct: 387 ----QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 442
Query: 1141 PPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPP 1200
PP+PPA P QA PP +A PPP P +LP P
Sbjct: 443 PPSPPASP-------PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495
Query: 1201 PLP-PTSDPLETPAP---SPSPSPSPQA 1224
P P P A SP +P PQA
Sbjct: 496 PASFPGQAPFSPSASLPMSPLATPPPQA 523
Score = 63.5 bits (153), Expect = 1e-09
Identities = 84/329 (25%), Positives = 117/329 (35%), Gaps = 51/329 (15%)
Query: 928 EEARAEGSGLD-PATSSEKASAK--AKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPL 984
EE A G + P S+ A A+ G T G P +R S A V +
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR--SRAAGTEVGLPRPAPSA 187
Query: 985 QGKFLSSGATSSLAAAGAGATTRPPPA---QSPTGSDTRLPAFLSFKFLKSP--ETRRDS 1039
+ + + G S+++A +TT P PA + G + PA S +P R
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247
Query: 1040 ERSHSPPKA-FHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGS------SRVQRSGPV 1092
+ P+A H + P G P R D P+ G + S P
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTP---PRKDAAPALGPLSSSPLATPSPSAPP 304
Query: 1093 DEALAEELEA-PRPEEEGSGTALAPVGAPALRTRRSRSPAPP-PPMPLPRPPTPPAGCWQ 1150
+ L+ P P A +G+P L+ S P+PP P+ P P PPA
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA---- 360
Query: 1151 WDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSL---------PPPP 1201
AL + PP A PP +P P + +L PPP
Sbjct: 361 ---------------LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405
Query: 1202 LPPTSDPLETPAPSP-SPSPSPQAVCWPS 1229
PP P PA P SPS +P + PS
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPS 434
Score = 32.7 bits (73), Expect = 2.2
Identities = 55/208 (26%), Positives = 66/208 (31%), Gaps = 41/208 (19%)
Query: 1044 SPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAP 1103
SPP +F PF + + P S A P P + +Q P + L+AP
Sbjct: 494 SPPASFPGQA--PFSPSASLPMSPLA--TPPPQAPPVLAAPLLQV--PPSPPASPTLQAP 547
Query: 1104 R-PEEEGSGTALAPVGAPALRTRRSRSPAPPP---PMPLPRPP-----------TPPAGC 1148
R P G T+ V P L + P PPP P P TP
Sbjct: 548 RRPPTPGPDTS---VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604
Query: 1149 WQWDGPWGCGGEGAAPRQALAAAE--------CPPCAMAGPPPAPQPLP---------GD 1191
GP G P LAA PP A G P AP P P G
Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664
Query: 1192 ASFYSLPPPPLPPTSDPLETPAPSPSPS 1219
+ Y P + P PSP S
Sbjct: 665 CTIYETEGPESATPAPGALDPGPSPGTS 692
Score = 32.3 bits (72), Expect = 2.9
Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 19/112 (16%)
Query: 1115 APVGAPALRTRRSRSPA----PPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAA 1170
A GA A RT +R+P PP P P PP PA G GA R+ LA
Sbjct: 8 AKAGAAA-RTPAARAPGLLTPRPPGSPRPPPPVTPAALRV------LGAAGAVGRKPLAE 60
Query: 1171 AECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPSPSPSP 1222
P AP+ P S PP S E P+ + SP P
Sbjct: 61 RAGGIGGATIPESAPRAGPTRTS--------RPPASGRGERAPPAKNTSPGP 104
>gi|30039694 zinc finger protein 598 [Homo sapiens]
Length = 904
Score = 66.2 bits (160), Expect = 2e-10
Identities = 105/423 (24%), Positives = 153/423 (36%), Gaps = 72/423 (17%)
Query: 869 GWVAEEMAKLEYQRREAFKRHERQAQHR------------YQQQQRRRREEEE---RQRH 913
G VA + Q R R++R+ + R QQ++ RR E++E R +
Sbjct: 316 GRVARAGTRGAQQSRRGSWRYKREEEDREVAAAVRASVAAQQQEEARRSEDQEEGGRPKK 375
Query: 914 AEHHARREHDSGG-REEARAEGSGLDPATSSEKASAKAKG-STAGGHGPERPKRPGSLLA 971
E AR D G R R +G G P +S + S G P PG+L
Sbjct: 376 EEAAARGPEDPRGPRRSPRTQGEGPGPKETSTNGPVSQEAFSVTGPAAPGCVGVPGALPP 435
Query: 972 PNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTG-SDTRLPAFLSF--- 1027
P+ +K + L SS +T++ A PA+ + + PA +S
Sbjct: 436 PSPKLKDEDFPSLSASTSSSCSTAATPGPVGLALPYAIPARGRSAFQEEDFPALVSSVPK 495
Query: 1028 ------KFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSS 1081
+ + + S++ PP + A G+ G G + G P
Sbjct: 496 PGTAPTSLVSAWNSSSSSKKVAQPPLSAQAT------GSGQPTRKAGKGSRGGRKGGPPF 549
Query: 1082 GSSRVQRSGPVDEALAEELEAPRPEEEGSGT-ALAPVGAPAL-RTRRSRSPAPPPPMPLP 1139
+ GP +EL + RP S T LA + + + ++ S P +P P
Sbjct: 550 TQEEEEDGGPA----LQELLSTRPTGSVSSTLGLASIQPSKVGKKKKVGSEKPGTTLPQP 605
Query: 1140 RPPTPPAGCWQW--------DGPWGC--GGEGAAPRQALAAAECPP----------C--- 1176
P T P G Q +GP G P A +A + PP C
Sbjct: 606 PPATCPPGALQAPEAPASRAEGPVAVVVNGHTEGPAPARSAPKEPPGLPRPLGSFPCPTP 665
Query: 1177 -----AMAGP-PPAPQPLPGDASFYSL---PPPPLPPTSDPLETPAPSPSP-SPSPQAVC 1226
A+ GP PP P PG ++ L PPPP P P+ P P S PSP C
Sbjct: 666 QEDFPALGGPCPPRMPPPPGFSAVVLLKGTPPPPPPGLVPPISKPPPGFSGLLPSPHPAC 725
Query: 1227 WPS 1229
PS
Sbjct: 726 VPS 728
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 65.9 bits (159), Expect = 2e-10
Identities = 91/361 (25%), Positives = 122/361 (33%), Gaps = 76/361 (21%)
Query: 923 DSGGREEARAEGS------GLDPATSSEKASAKAKGSTAGGHGPERPKRPGSLLAPNNVM 976
DSG A ++G+ P S K + G GP+ P G+L +P
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI--GNLSSP---- 827
Query: 977 KLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGS------------------- 1017
+ P++ FL + S + + ATT P SP G+
Sbjct: 828 ----VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPK 883
Query: 1018 DTRLPAFLSFKFLK-SPETRRD------SERSHSPPKAFHAGKLFPFGGTRAEPGSNGAG 1070
+T P+ ++ F K P T S S SP KA RA P G
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA------------RATPAPKGIP 931
Query: 1071 GQARPDG--TPSSGSSRVQRSGPVDEA---LAEELEAPRPEEEGSGTALAPVGAPALRTR 1125
P G TP + + + GP + A P +G +P GAP
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA 991
Query: 1126 RSRSPAPPPPMPLPR---------PPTPPAGCWQWDGPWGCGGEGAA----PRQALAAAE 1172
SP P P P+ PP+P P G AA P+ + AA
Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051
Query: 1173 CP---PCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPA-PSPSPSPSPQAVCWP 1228
P P A P+P+ P S P PP P PA PSP +P P A P
Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 1229 S 1229
S
Sbjct: 1112 S 1112
Score = 57.8 bits (138), Expect = 6e-08
Identities = 69/268 (25%), Positives = 85/268 (31%), Gaps = 39/268 (14%)
Query: 995 SSLAAAGAGATTRPPPAQSPTGSDTRL-----------PAFLSFKFLKSPETRRDSERSH 1043
S L + + T RPP + G DT + +FL L ++ +H
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 1044 SPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEA--LAEELE 1101
SP G P T P G + TPS + + GP A A L
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSP--KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 1102 APRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEG 1161
+ + AP G PA S SP P P PP+P G W
Sbjct: 913 MTSSSPKKARATPAPKGIPA-----SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967
Query: 1162 AAPRQALAAAECP-----PCAMAGPPPAPQPLPGDASFYSLPPPPL----PPTSDPLETP 1212
A P P P A PP+P+ P S P PP P P TP
Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027
Query: 1213 APS----------PSPSPSPQAVCWPSG 1230
P PSP SP A P G
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKG 1055
Score = 55.1 bits (131), Expect = 4e-07
Identities = 80/293 (27%), Positives = 95/293 (32%), Gaps = 50/293 (17%)
Query: 939 PATSSEKASAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLA 998
PAT S K + +T P PK G L P P +G + AT
Sbjct: 1094 PATPSPKGAPMPPAAT-----PPSPK--GGLATP----------PHKGAPTTPAATPP-- 1134
Query: 999 AAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFG 1058
+ G PPP +PT P SP+ + P A P G
Sbjct: 1135 -SPKGGLATPPPKGAPTTPAATPP---------SPKGGLATPPPKGAPTTPAATPPSPKG 1184
Query: 1059 GTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVG 1118
G A P GA P TP S + P P P+ G +P G
Sbjct: 1185 GL-ATPSPKGA--PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK--GGLATPSPKG 1239
Query: 1119 APALRTRRSRSP----APPPPMPLPRPP--TPPAGCWQWDGPWGCGGEGAAPRQALAAAE 1172
AP SP A PPP P PP TPP+ G AP A+
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPS----LKGGLATPPHKGAPNPAVVTPP 1295
Query: 1173 CPPCAMAGPPPAPQPLPGDASFYSLPPPP--LPPTSDPLETPAPSPSPSPSPQ 1223
P A PP P P A+ PP P P T P P P PSP+
Sbjct: 1296 SPKGGPATSPPKGAPTPPAAT----PPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
Score = 47.8 bits (112), Expect = 7e-05
Identities = 70/283 (24%), Positives = 91/283 (32%), Gaps = 29/283 (10%)
Query: 963 PKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGSDTRLP 1022
PK + AP L K ++ A + A+ + PPA +P S P
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP-SPKGGP 954
Query: 1023 AFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSG 1082
A S K+ +P P G P T P A + TP +
Sbjct: 955 ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014
Query: 1083 SSRVQRSGPVDEALAEELEAPR----PEEEGSGTALA-PVGAPALRTRRSRSPAPPPPMP 1137
+ + P + P P +GS A P GAP SP P P
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074
Query: 1138 -LPRPPTPPAGCWQWDGPWGCGGEGA-----APRQALAAAECPPCAMAGPP-------PA 1184
L PTPPA P GG AP A P +A PP PA
Sbjct: 1075 SLKGAPTPPAAT----PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 1185 PQPLPGDASFYSLPPPPLPPTSDPLETPAP-----SPSPSPSP 1222
P P + PPP PT+ P+P +P P +P
Sbjct: 1131 ATP-PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172
Score = 46.6 bits (109), Expect = 1e-04
Identities = 80/312 (25%), Positives = 102/312 (32%), Gaps = 69/312 (22%)
Query: 939 PATSSEKASAKAKGSTAGGHG-----PERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGA 993
P T S K +T G P PKR ++ +P +IPL K
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK------ 1413
Query: 994 TSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGK 1053
A A TR A +P+ D PA K+P T S PK
Sbjct: 1414 -----KAPATPVTR-EGAATPSKGDLTPPAVTPVSLKKAPAT--------SAPK------ 1453
Query: 1054 LFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTA 1113
G A P S G P TP S P + +++ ++ T
Sbjct: 1454 -----GGPATPSSK--GDPTLPAVTPPS---------PKEPPAPKQVATSSSPKKAPATP 1497
Query: 1114 LAPVGAPALRTRRSRSPAPPPPMPLPR--PPTPPAGCWQWDGPWGCGGEGAAPRQAL--- 1168
AP+GAP L SP P P R P P A P AP++AL
Sbjct: 1498 -APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP-----ATLAPKEALIPP 1551
Query: 1169 -AAAECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETP----------APSPS 1217
P A P P P + S PP P T +P +PSP
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
Query: 1218 PSPSPQAVCWPS 1229
+P+P AV PS
Sbjct: 1612 EAPTPPAVTPPS 1623
Score = 45.8 bits (107), Expect = 2e-04
Identities = 63/252 (25%), Positives = 81/252 (32%), Gaps = 35/252 (13%)
Query: 1001 GAGATTRPPPAQSPT----GSDTRLPAFLSFKFLKSPETRRDSERSHSPPKA-FHAGKLF 1055
G A T P P + P D PA + K+P T E + +P K +
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439
Query: 1056 PFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALA 1115
P +A S GG A P V P + +++ ++ T A
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP-A 1498
Query: 1116 PVGAPALRTRRSRSPAPPPPMPLPR--PPTPPAGCWQWDGPWGCGGEGAAPRQALA---- 1169
P+GAP L SP P P R P P A P AP++AL
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP-----ATLAPKEALIPPAM 1553
Query: 1170 ----------------AAECPPCAMAGPPPA--PQPLPGDASFYSLPPPPLPPTSDPLET 1211
A P A PPA P G S L PP + P E
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613
Query: 1212 PAPSPSPSPSPQ 1223
P P PSP+
Sbjct: 1614 PTPPAVTPPSPE 1625
Score = 45.1 bits (105), Expect = 4e-04
Identities = 78/300 (26%), Positives = 98/300 (32%), Gaps = 39/300 (13%)
Query: 939 PATSSEKASAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLA 998
PAT S K + +T P PK + +P + P K +
Sbjct: 977 PATPSPKGAPTPPAAT-----PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031
Query: 999 AAGAGATTRPPPAQSPTGSDTRLPA---FLSFKFLKSPETRRDSERSHSPPKAFHAGKLF 1055
A+ A T P P SP T LP L SP+ + P A
Sbjct: 1032 ASTPPAATPPSPKGSPAA--TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 1056 PFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALA 1115
P GG A P GA P TP S + + P + A P +G
Sbjct: 1090 PKGGP-ATPSPKGA--PMPPAATPPSPKGGL--ATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 1116 PVGAPALRTRRSRSP----APPPPMPLPRPP--TPPAGCWQWDGPWGCGGEGAAPRQALA 1169
P GAP SP A PPP P P TPP+ G AP A
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP----KGGLATPSPKGAPTTPAA 1200
Query: 1170 AAECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPSPS------PSPQ 1223
P +A P P P A+ PP P L TP+P +P+ PSP+
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAAT----PPSP----KGGLATPSPKGAPTTPAATPPSPK 1252
Score = 42.7 bits (99), Expect = 0.002
Identities = 83/322 (25%), Positives = 105/322 (32%), Gaps = 54/322 (16%)
Query: 939 PATSSEKASAKAKGS-TAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSL 997
PA AS KG+ T P PK + +P P K AT S
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK--GGPATPSP 982
Query: 998 AAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKA-FHAGKLFP 1056
A PP SP G PA S K +P SP F G P
Sbjct: 983 KGAPTPPAATPP---SPKGG----PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035
Query: 1057 FGGTRAEPGSNGAGGQARPDGTPSSGSSRVQ--RSGPVDEALAEELEAPR---PEEEGSG 1111
T P + A P G P++ ++ + + GP +L P P +G
Sbjct: 1036 PAATPPSPKGSPAATPL-PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 1112 TALAPVGAPALRTRRSRSP-----APP----PPMPLPRPPTPPAGCWQWDGPWGCGGEGA 1162
+P GAP SP PP P P PP+P G P G
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL-ATPPPKG------ 1147
Query: 1163 APRQALAAAECPPCAMAGPPPAPQPL------PGDASFYSLPPP---PLPPTSDP----- 1208
AP A P +A PPP P P + P P P P + P
Sbjct: 1148 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207
Query: 1209 -LETPAPSPSPS------PSPQ 1223
L TP+P +P+ PSP+
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPK 1229
Score = 38.1 bits (87), Expect = 0.052
Identities = 41/167 (24%), Positives = 59/167 (35%), Gaps = 13/167 (7%)
Query: 1075 PDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVG----APALRTRRSRSP 1130
P P S +++ + LE P P+ SGTAL P+G AP P
Sbjct: 53 PQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS-SGTAL-PLGTAPEAPTFLPNLIGPP 110
Query: 1131 APPPPMPLPRPPTPPA--GCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPL 1188
P + L P P G P AP ++ PP + PP
Sbjct: 111 ISPAALALASPMIAPTLKGTPSSSAPLAL--VALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 1189 PGDASFYSLPPPPLPPTSDPLETPA---PSPSPSPSPQAVCWPSGWH 1232
G S P P P ++ + P+ P+P +PSP + +H
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYH 215
Score = 38.1 bits (87), Expect = 0.052
Identities = 67/242 (27%), Positives = 86/242 (35%), Gaps = 42/242 (17%)
Query: 1004 ATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAE 1063
A T P P ++PT PA K P T SPP + K P
Sbjct: 1604 AVTSPSPKEAPTP-----PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP------- 1651
Query: 1064 PGSNGAGGQARPDGT-PSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPAL 1122
++ A + T P + + GP AL E L AP PE TA G
Sbjct: 1652 --TSPASVTCKMGATVPQASKGLPAKKGPT--ALKEVLVAPAPESTPIITAPTRKGPQTK 1707
Query: 1123 RTRRSRSPAPPPPM-------PLPRPPTPPAGCWQWDGPWGCGGEGAA--PRQALAAAEC 1173
++ + P P P PL P Q D G+ A+ P+ LA
Sbjct: 1708 KSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA---- 1763
Query: 1174 PPCAMAGPPPAPQ------PLPGDASFYSLPPPPLPPTSDPLETPAPSPSPSPSPQAVCW 1227
PP + A P P P AS + P PP+ S PL APSP P+ P+
Sbjct: 1764 PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPV---SLPL---APSPVPTLPPKQQFL 1817
Query: 1228 PS 1229
PS
Sbjct: 1818 PS 1819
Score = 33.1 bits (74), Expect = 1.7
Identities = 64/283 (22%), Positives = 96/283 (33%), Gaps = 40/283 (14%)
Query: 939 PATSSEKASAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSS--GATSS 996
PAT + K + + T + P P S+ K+ +P K L + G T+
Sbjct: 1628 PATPAPKGTPTSPPVTPSSL-KDSPTSPASVTC-----KMGATVPQASKGLPAKKGPTAL 1681
Query: 997 LAAAGAGATTRPPPAQSPT--GSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKL 1054
A A P +PT G T+ + S P + S+ P L
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK---GPLSTVAPAPL 1738
Query: 1055 FPF--GGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGT 1112
P ++ G + + P P S +S P+ A E++ P+PE
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKGPLAPPESKAST-----PLTAAAFEKV-LPKPESASVSA 1792
Query: 1113 ALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAE 1172
A P+PP +PL P P Q P G +P + LA A+
Sbjct: 1793 A----------------PSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPAD 1836
Query: 1173 CPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPS 1215
PP +P+ G F S+ P S + P PS
Sbjct: 1837 EDELLPLIPP---EPISGGVPFQSVLVNMPTPKSAGIPVPTPS 1876
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 65.1 bits (157), Expect = 4e-10
Identities = 74/248 (29%), Positives = 102/248 (41%), Gaps = 28/248 (11%)
Query: 523 PRRLEPQADEGGGGGSGGGGRRCLSGGCGAPEEEEEAALVERRRAGEGGEEGDGPPGGKE 582
P +L P+ GGGG + + EEEEE E E EE D ++
Sbjct: 857 PPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEED 916
Query: 583 EDEDDEEEEDEEEEEDEEEGEEGGLL---------DCGLRLKKVSFAERGA-------GR 626
E+E EEEE+EEEE +EE EE G L + L++V E G G
Sbjct: 917 EEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGA 976
Query: 627 RRPGPSPEALLEEGSPTMV--EKGLEPGVFTLAEE--DDEAEGAPGSPEREPPAILFRRA 682
P P AL SP V E EPG+ EE +E GA +P P A L +
Sbjct: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA-LPSQG 1035
Query: 683 GGEGRDQGPDGGPDP-----EPGSNSDSTRRQRRQNRSSWIDPPEEEHSPQ--LTQAELE 735
E + P GP P E S + + ++ S + PP E + + T+ E E
Sbjct: 1036 EVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAE 1095
Query: 736 SCMKKYED 743
+ +K +D
Sbjct: 1096 ALQEKEQD 1103
Score = 47.4 bits (111), Expect = 9e-05
Identities = 63/260 (24%), Positives = 82/260 (31%), Gaps = 85/260 (32%)
Query: 982 IPLQGKFLSSGATSS---LAAAGAGATTRPPPAQSPTGSDTRLPAFLSF--KFLKSPETR 1036
+P G S+G S + +AG + RP P + +P +S + L PE
Sbjct: 671 MPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENH 730
Query: 1037 RDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTP-------SSGSSRVQRS 1089
R G+ +P P GTP + RV R
Sbjct: 731 R--------------------AGSNEDP-------ILAPSGTPPPTIPPDETFGGRVPRP 763
Query: 1090 GPV--DEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAG 1147
V D+ A ++E + + P G P P PP PP+G
Sbjct: 764 AFVHYDKEEASDVEISLESDSDDSVVIVPEGLP------------------PLPPPPPSG 805
Query: 1148 CWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLP--PPPLPPT 1205
A PP A GPP A P+P LP P PLPP
Sbjct: 806 -----------------------ATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPP 842
Query: 1206 SDPLETPAPSPSPSPSPQAV 1225
P P P P P PQ V
Sbjct: 843 PPP-PPPVPGPVTLPPPQLV 861
Score = 42.4 bits (98), Expect = 0.003
Identities = 69/269 (25%), Positives = 88/269 (32%), Gaps = 61/269 (22%)
Query: 989 LSSGATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKA 1048
+SS + +L A R PP Q P G PA + PE P
Sbjct: 616 VSSFCSEALVTCAALTHPRVPPLQ-PMGPTCPTPAPVP-----PPEA----------PSP 659
Query: 1049 FHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPR---- 1104
F A P G + AG PS+G R GP A L P
Sbjct: 660 FRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSV 719
Query: 1105 -------PEEEGSGTALAPVGAPALRTRRSRSPAPPPPMP--------LPRPPTPPAGCW 1149
PE +G+ P+ AP S PPP +P +PRP
Sbjct: 720 PPRLLPGPENHRAGSNEDPILAP--------SGTPPPTIPPDETFGGRVPRPAFV----- 766
Query: 1150 QWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPP-------PPL 1202
+D E + + + P G PP P P P A+ + P PP+
Sbjct: 767 HYDKEEASDVEISLESDSDDSVVIVP---EGLPPLPPPPPSGATPPPIAPTGPPTASPPV 823
Query: 1203 PPTSDPLETPA---PSPSPSPSPQAVCWP 1228
P +P E PA P P P P P V P
Sbjct: 824 PAKEEPEELPAAPGPLPPPPPPPPPVPGP 852
Score = 35.4 bits (80), Expect = 0.34
Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 1167 ALAAAECPPCAMAGPP---PAPQPLPGDASFYSLPP--PPLP-PTSDPLETPAPSPSPSP 1220
AL PP GP PAP P P S + PP PP P P+ + + P PS P
Sbjct: 629 ALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGP 688
Query: 1221 SPQAVCWPS 1229
P A PS
Sbjct: 689 MPSAGPVPS 697
Score = 33.1 bits (74), Expect = 1.7
Identities = 39/135 (28%), Positives = 44/135 (32%), Gaps = 7/135 (5%)
Query: 1093 DEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAP-PPPMPLPRPPTPPAGCWQW 1151
DE EELE E G+ GAP T P P PP P P P +
Sbjct: 950 DEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEV 1009
Query: 1152 DGPWGCGGEGAAPRQALAAAECP---PCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDP 1208
+ P GA LA P G PA P P + P PPT
Sbjct: 1010 EEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQE---LVEEEPSAPPTLLE 1066
Query: 1209 LETPAPSPSPSPSPQ 1223
ET S P P+
Sbjct: 1067 EETEDGSDKVQPPPE 1081
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 64.7 bits (156), Expect = 5e-10
Identities = 70/251 (27%), Positives = 88/251 (35%), Gaps = 55/251 (21%)
Query: 993 ATSSLAAAGAGATTRPP--PAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFH 1050
A +A+ A A T PP P+++P LP S + P DS PP
Sbjct: 549 AKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD-SGTIIPPPPAPGDSTTPPPPPPPPP 607
Query: 1051 AGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGS 1110
P G + P S GG A P SG + + P+ E + P P
Sbjct: 608 PPPPLPGGVCISSPPSL-PGGTAISPPPPLSGDATIPPPPPLPEGVG----IPSPSSLPG 662
Query: 1111 GTALAPVGAPALRTRRSRSPAPPPPMP----LPRPPTPPAGCWQWDGPWGCGGEGAAPRQ 1166
GTA+ P P +R P PPPP+P +P PP P G
Sbjct: 663 GTAIPP---PPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG------------------- 700
Query: 1167 ALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPP-------LPPTSDPLETPAPSPSPS 1219
AG PP P PLPG +PPPP +PP + P P P
Sbjct: 701 -----------EAGMPPPPPPLPGGP---GIPPPPPFPGGPGIPPPPPGMGMPPPPPFGF 746
Query: 1220 PSPQAVCWPSG 1230
P A P G
Sbjct: 747 GVPAAPVLPFG 757
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 64.7 bits (156), Expect = 5e-10
Identities = 70/251 (27%), Positives = 88/251 (35%), Gaps = 55/251 (21%)
Query: 993 ATSSLAAAGAGATTRPP--PAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFH 1050
A +A+ A A T PP P+++P LP S + P DS PP
Sbjct: 558 AKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD-SGTIIPPPPAPGDSTTPPPPPPPPP 616
Query: 1051 AGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGS 1110
P G + P S GG A P SG + + P+ E + P P
Sbjct: 617 PPPPLPGGVCISSPPSL-PGGTAISPPPPLSGDATIPPPPPLPEGVG----IPSPSSLPG 671
Query: 1111 GTALAPVGAPALRTRRSRSPAPPPPMP----LPRPPTPPAGCWQWDGPWGCGGEGAAPRQ 1166
GTA+ P P +R P PPPP+P +P PP P G
Sbjct: 672 GTAIPP---PPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG------------------- 709
Query: 1167 ALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPP-------LPPTSDPLETPAPSPSPS 1219
AG PP P PLPG +PPPP +PP + P P P
Sbjct: 710 -----------EAGMPPPPPPLPGGP---GIPPPPPFPGGPGIPPPPPGMGMPPPPPFGF 755
Query: 1220 PSPQAVCWPSG 1230
P A P G
Sbjct: 756 GVPAAPVLPFG 766
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 64.3 bits (155), Expect = 7e-10
Identities = 51/155 (32%), Positives = 58/155 (37%), Gaps = 39/155 (25%)
Query: 1091 PVDEALAEEL---EAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAG 1147
PVD A +E + PR E+ + T P P L + P PPPP PLP
Sbjct: 396 PVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLP-------- 447
Query: 1148 CWQWDGPWGCGGEGAAPRQALAAAECPPC-----AMAGP-PPAPQPLPGDASFYSLPPPP 1201
+ +AL A PP AMA P PP P PLPG F PPPP
Sbjct: 448 --------------SVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPP 493
Query: 1202 LPPTSDPLETP--------APSPSPSPSPQAVCWP 1228
LP P P P P P P C P
Sbjct: 494 LPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Score = 37.7 bits (86), Expect = 0.068
Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 7/68 (10%)
Query: 1164 PRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPP--LPPTSDPLETPAPSPSPSPS 1221
PR A PP PPP P LPG ++ PPPP LP AP P P P
Sbjct: 411 PRALEQQASTPP-----PPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPG 465
Query: 1222 PQAVCWPS 1229
A+ P+
Sbjct: 466 LGAMAPPA 473
Score = 32.3 bits (72), Expect = 2.9
Identities = 26/71 (36%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 1165 RQALAAAECPPCAMAGPPPA-----PQPLPGDASFYSLPPPP-LPPTSDPLETPAPSPSP 1218
+Q AAA C P A P+ L AS PPPP L P S P P P P
Sbjct: 386 QQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPP 445
Query: 1219 SPSPQAVCWPS 1229
PS A P+
Sbjct: 446 LPSVGAKALPT 456
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 64.3 bits (155), Expect = 7e-10
Identities = 51/155 (32%), Positives = 58/155 (37%), Gaps = 39/155 (25%)
Query: 1091 PVDEALAEEL---EAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAG 1147
PVD A +E + PR E+ + T P P L + P PPPP PLP
Sbjct: 396 PVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLP-------- 447
Query: 1148 CWQWDGPWGCGGEGAAPRQALAAAECPPC-----AMAGP-PPAPQPLPGDASFYSLPPPP 1201
+ +AL A PP AMA P PP P PLPG F PPPP
Sbjct: 448 --------------SVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPP 493
Query: 1202 LPPTSDPLETP--------APSPSPSPSPQAVCWP 1228
LP P P P P P P C P
Sbjct: 494 LPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528
Score = 37.7 bits (86), Expect = 0.068
Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 7/68 (10%)
Query: 1164 PRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPP--LPPTSDPLETPAPSPSPSPS 1221
PR A PP PPP P LPG ++ PPPP LP AP P P P
Sbjct: 411 PRALEQQASTPP-----PPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPG 465
Query: 1222 PQAVCWPS 1229
A+ P+
Sbjct: 466 LGAMAPPA 473
Score = 32.3 bits (72), Expect = 2.9
Identities = 26/71 (36%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 1165 RQALAAAECPPCAMAGPPPA-----PQPLPGDASFYSLPPPP-LPPTSDPLETPAPSPSP 1218
+Q AAA C P A P+ L AS PPPP L P S P P P P
Sbjct: 386 QQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPP 445
Query: 1219 SPSPQAVCWPS 1229
PS A P+
Sbjct: 446 LPSVGAKALPT 456
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 63.5 bits (153), Expect = 1e-09
Identities = 89/356 (25%), Positives = 131/356 (36%), Gaps = 53/356 (14%)
Query: 903 RRREEEERQRHAEHHARREHDSGGREEARAEG---SGLDPATSSEKASA---KAKGSTAG 956
R+ EEE +H A + + G E ++ G G P + + + +++G AG
Sbjct: 308 RKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAG 367
Query: 957 GHGPERPK------------------RPGSLLAPNNVMKLKQI-IPLQGKFLSSGA--TS 995
GHG +RP+ +P + P + ++++I + L+G LS G+ T
Sbjct: 368 GHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTG 427
Query: 996 SLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSER--SHSPPKAFHAGK 1053
+ G P + P G+ A K K E DS S AG
Sbjct: 428 TQEVGGQDPGEAVQPCRQPLGARV---ADKVRKRRKVDEGAGDSAAVASGGAQTLALAGS 484
Query: 1054 LFPFGGTRAEPGSNGA-----GGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEE 1108
P G +A NG G +GTP S S + GP A + A P E
Sbjct: 485 PAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPS---ETPGPSPAGPAGDEPAESPSET 541
Query: 1109 GSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQAL 1168
P G + S +P P P P P + GP G P ++
Sbjct: 542 PGPRPAGPAGDEPAESP-SETPGPRPAGPAGDEPAESPS--ETPGPSPAGPTRDEPAESP 598
Query: 1169 AAAECP-PCAMAGPPPAPQP--LPGDASFYSLPPPPLPPTSDPLETPAPSPSPSPS 1221
+ P P AG PA P PG P P P +P E+P+ +P PSP+
Sbjct: 599 SETPGPRPAGPAGDEPAESPSETPG-------PRPAGPAGDEPAESPSETPGPSPA 647
Score = 33.9 bits (76), Expect = 0.98
Identities = 87/388 (22%), Positives = 140/388 (36%), Gaps = 74/388 (19%)
Query: 849 LEHF-ALLLKYLIHVAIP--DIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRR 905
LEHF A L+++ + + ++PG + L+Y RH+R+ + + R R
Sbjct: 225 LEHFQAPLVRFFLEETLVRRELPG---VRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPR 281
Query: 906 EE-----EERQRHAEHHARREHDSGGREEARAEGSGLDP--ATSSEKASAKAKGSTAGGH 958
+ +++ R + + H G + EGS DP S++ + + S GG
Sbjct: 282 CKFVWGPQDKLRRFKPSSL-PHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGR 340
Query: 959 GPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGSD 1018
E P+ P S+ P + L++ S AG RP P SP S
Sbjct: 341 VDEGPQ-PRSV-EPQDAGPLER--------------SQGDEAGGHGEDRPEPL-SPKESK 383
Query: 1019 TRLPAFLSFKFLKSPETRRDSERSH-SPPKAFHAGKL-FPFGGTRAEPGSNGAGGQARPD 1076
R K +RR+ + P A K+ G GS G Q
Sbjct: 384 KR----------KLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGG 433
Query: 1077 GTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPM 1136
P ++ P+ +A+++ R +EG+G + A A + SPAP
Sbjct: 434 QDPGEAVQPCRQ--PLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGH- 490
Query: 1137 PLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYS 1196
P AG + G P++ G P +P PG
Sbjct: 491 -------PKAGHSENGVEEDTEGR-TGPKE-------------GTPGSPSETPG------ 523
Query: 1197 LPPPPLPPTSDPLETPAPSPSPSPSPQA 1224
P P P +P E+P+ +P P P+ A
Sbjct: 524 -PSPAGPAGDEPAESPSETPGPRPAGPA 550
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 62.4 bits (150), Expect = 3e-09
Identities = 101/373 (27%), Positives = 137/373 (36%), Gaps = 71/373 (19%)
Query: 898 QQQQRRRREEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKAS--AKAKGSTA 955
Q+ R EE + A +R S G AR + SG P T S + ++A G+
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAG---ARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 956 GGHGPERPKRPG----------------SLLAPNNVMKLKQIIPLQGKFLSSGATSSLAA 999
G P RP S P+ + + P G L A+ SL++
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR---PSAGGGLQRPASRSLSS 244
Query: 1000 AGAGATTRPPPAQS-PTGSDT-RLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPF 1057
+ AT PA+S P+ T R PA S K + R + + PP+ A L P
Sbjct: 245 S---ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT--PPRKDAAPALGPL 299
Query: 1058 GGTRAEPGSNGAG--GQARPD--GTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTA 1113
+ S A QA P TP S S Q + P+ A P + S A
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359
Query: 1114 LAP------VGAPALRTRRSRSPAPP-PPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQ 1166
P +G+P L+ S P+PP P+ P P PPA
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA-------------------L 400
Query: 1167 ALAAAECPPCAMAGPPPAPQPLPGDASFYSL---------PPPPLPPTSDPLETPAPSP- 1216
AL + PP A PP +P P + +L PPP PP P PA P
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
Query: 1217 SPSPSPQAVCWPS 1229
SPS +P + PS
Sbjct: 461 SPSATPPSQAPPS 473
Score = 58.5 bits (140), Expect = 4e-08
Identities = 88/324 (27%), Positives = 122/324 (37%), Gaps = 45/324 (13%)
Query: 918 ARREHDSGG---REEARAEGSGLDPATSSEKASAKAKGSTAGGHGPERPKRPG--SLLAP 972
ARR +GG R +R+ S P +S ++ A+G+ P +PK G +L P
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
Query: 973 NNVMKLKQIIPLQGKFLSSG-ATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLK 1031
K P G SS AT S +AA ++ PP T + L L+
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAA---LQSQAPPTLPATPHSSSLTCQLATPLPL 340
Query: 1032 SPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGG---QARPDGTPSSGSSRVQR 1088
+P S S P + P T + G QA PS S +
Sbjct: 341 APP-------SPSAPPSLQTLPSPP--ATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391
Query: 1089 SGP-VDEALA-EELEAPRPEEEGSGTALAPVGAP------ALRTRRSRSP-APPPPMPLP 1139
P ALA L+AP P S L+P+ P AL ++P +PPP P+
Sbjct: 392 PPPQAPPALALPPLQAP-PSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
Query: 1140 RPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPP 1199
P +PPA P QA + PP + PPA P+ A+ PP
Sbjct: 450 APFSPPASP-------PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT----PP 498
Query: 1200 PPLPP--TSDPLETPAPSPSPSPS 1221
P PP + PL+ P P P+
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPA 522
Score = 37.7 bits (86), Expect = 0.068
Identities = 82/337 (24%), Positives = 111/337 (32%), Gaps = 72/337 (21%)
Query: 963 PKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTR--PPPAQSPTGSDT- 1019
P P S AP ++ Q +P S AT+SL + AT P P SP +
Sbjct: 339 PLAPPSPSAPPSL----QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394
Query: 1020 RLPAFLSFKFLKSPETRRDSER----SHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARP 1075
+ P L+ L++P + S + P+A +A + + P S P
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454
Query: 1076 DGTPSSGSSRVQRSGPVDEALAEELEAP-----RPEEEGSGT----ALAPVGAPALRTRR 1126
+P S S A L+ P P S T A P+ AP L+ +
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514
Query: 1127 SRSPAPP----PPMP-LPRPPTPPAGCWQWD-------GPWGCGGEGAAPRQALAAAECP 1174
APP PP+ LP PP G + P A P A + P
Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574
Query: 1175 PCAMAGP-------PPAPQP---LPGDASFYSLPP-PPLPPTSDPLET------------ 1211
P A P PP P P + G +L P PP PP+ P T
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
Query: 1212 --------------PAPSPSPSPSPQA---VCWPSGW 1231
P + SP P A C P+ W
Sbjct: 635 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671
Score = 36.2 bits (82), Expect = 0.20
Identities = 37/113 (32%), Positives = 43/113 (38%), Gaps = 12/113 (10%)
Query: 1115 APVGAPALRTRRSRSPA----PPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAA 1170
A GA A RT +R+P PP P P PP PA G GA R+ LA
Sbjct: 8 AKAGAAA-RTPAARAPGLLTPRPPGSPRPPPPVTPAALRV------LGAAGAVGRKPLAE 60
Query: 1171 AECPPCAMAGPPPAPQPLP-GDASFYSLPPPPLPPTSDPLETPAPSPSPSPSP 1222
P AP+ P A S P PP S E P+ + SP P
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113
Score = 32.7 bits (73), Expect = 2.2
Identities = 55/208 (26%), Positives = 66/208 (31%), Gaps = 41/208 (19%)
Query: 1044 SPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAP 1103
SPP +F PF + + P S A P P + +Q P + L+AP
Sbjct: 533 SPPASFPGQA--PFSPSASLPMSPLA--TPPPQAPPVLAAPLLQV--PPSPPASPTLQAP 586
Query: 1104 R-PEEEGSGTALAPVGAPALRTRRSRSPAPPP---PMPLPRPP-----------TPPAGC 1148
R P G T+ V P L + P PPP P P TP
Sbjct: 587 RRPPTPGPDTS---VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
Query: 1149 WQWDGPWGCGGEGAAPRQALAAAE--------CPPCAMAGPPPAPQPLP---------GD 1191
GP G P LAA PP A G P AP P P G
Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 703
Query: 1192 ASFYSLPPPPLPPTSDPLETPAPSPSPS 1219
+ Y P + P PSP S
Sbjct: 704 CTIYETEGPESATPAPGALDPGPSPGTS 731
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 61.6 bits (148), Expect = 4e-09
Identities = 80/333 (24%), Positives = 112/333 (33%), Gaps = 54/333 (16%)
Query: 895 HRYQQQQRRRREEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKASAKAKGST 954
H QQQQ+++++++++Q+ +HH G EG SS A A +
Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGG------SSHHAHPYAMSPS 535
Query: 955 AGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSP 1014
G P P P L P++ + Q P SS +SS + G+ + P P+Q P
Sbjct: 536 LGSLRP-YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP 594
Query: 1015 TGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQ-A 1073
G+ + F P S A S+ AG + A
Sbjct: 595 QGA--------PYPFPPVPTVTTSSA---------------TLSTVIATVASSPAGYKTA 631
Query: 1074 RPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPP 1133
P G P G R G A + P +GT G + P P
Sbjct: 632 SPPGPPPYG-KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSP 690
Query: 1134 PPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPP--APQPLPGD 1191
P P PP P+G L + PP A A PP A Q
Sbjct: 691 TVGPGPLPPAGPSG--------------------LPSLPPPPAAPASGPPLSATQIKQEP 730
Query: 1192 ASFYSLPPPPLPPTSDPLETPAPSPSPSPSPQA 1224
A Y P P+PP P P PS + Q+
Sbjct: 731 AEEYETPESPVPPARSPSPPPKVVDVPSHASQS 763
Score = 42.0 bits (97), Expect = 0.004
Identities = 80/362 (22%), Positives = 121/362 (33%), Gaps = 54/362 (14%)
Query: 872 AEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRREEEERQRHAEHHARREHDSGGREEAR 931
+EE+++ E + A K+ + + Q+ R + + + + S +
Sbjct: 73 SEEISESESEETNAPKKTKTE-------QELPRPQSPSDLDSLDGRSLNDDGSSDPRDID 125
Query: 932 AEGSGLDPATSSEKASAKAKGSTAG-GHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLS 990
+ P+ S + S++G GP RP P L P+ + P Q +
Sbjct: 126 QDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP--QPPDSTPRQPE--- 180
Query: 991 SGATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFH 1050
A+ P P+ +PTG + + P +R +PP
Sbjct: 181 -------------ASFEPHPSVTPTGYHAPM---------EPPTSRMFQAPPGAPPPH-- 216
Query: 1051 AGKLFPFGGT----RAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAP--R 1104
+L+P GGT P GG A G P+ G + P+ + + AP +
Sbjct: 217 -PQLYP-GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274
Query: 1105 PEEEGSGTALAPVGAPALRTRRSRSPAPPPPM--PLPRPPTPPAGCWQWDGPWGCGGEGA 1162
P G P P PPPP PL P G G G
Sbjct: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL----GAQPLPGHLP 330
Query: 1163 APR-QALAAAECPPCAMAGPPPAPQP--LPGDASFYSLPPPPLPPTSDPLETPAPSPSPS 1219
+P PP GP AP P LP +S PP P +S + A S S S
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Query: 1220 PS 1221
S
Sbjct: 391 SS 392
Score = 41.6 bits (96), Expect = 0.005
Identities = 70/316 (22%), Positives = 113/316 (35%), Gaps = 43/316 (13%)
Query: 947 SAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATT 1006
S A G GG P K P +P+++ P ++SS +AA + +++
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Query: 1007 RPPPAQSPTGSDTRLPAFL-SFKFLKS------------PETRRDSERSHSPPKAFHAGK 1053
+ SP + LP++ SF S P + S PP G+
Sbjct: 391 SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGR 450
Query: 1054 LFPFGGTRAEPG----SNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEA------- 1102
L + A PG S GA A P + + Q+ + ++ +
Sbjct: 451 LL--ANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508
Query: 1103 -------PRPEEEGSGTALAPVG-APALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGP 1154
P P E GS P +P+L + R P PP P LP P + + + GP
Sbjct: 509 PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR---PYPPGPAHLPPPHSQVS--YSQAGP 563
Query: 1155 WGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAP 1214
G ++ + + PC+ P+P P A + P P + +S L T
Sbjct: 564 NGPPVSSSSNSSSSTSQGSYPCSH----PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619
Query: 1215 SPSPSPSPQAVCWPSG 1230
+ + SP+ P G
Sbjct: 620 TVASSPAGYKTASPPG 635
Score = 38.1 bits (87), Expect = 0.052
Identities = 56/235 (23%), Positives = 76/235 (32%), Gaps = 36/235 (15%)
Query: 994 TSSLAAAGAGATTRPP--PAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHA 1051
T+ ++ + +GA+ PP P +P G P + H P
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNL------------PSAPPPANFPHVTPNLPPP 304
Query: 1052 GKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSG 1111
L P A P G G Q P PS + G P PE+ G
Sbjct: 305 PALRPLNNASASPP--GLGAQPLPGHLPSPHAMGQGMGGL----------PPGPEK---G 349
Query: 1112 TALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAA- 1170
LAP +L S +PAPP P + A QAL +
Sbjct: 350 PTLAP-SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSY 408
Query: 1171 --AECPPCAMA---GPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPSPSP 1220
+ PP +++ PP QP + +S PPP PP L P P P
Sbjct: 409 PHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFP 463
Score = 32.3 bits (72), Expect = 2.9
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 870 WVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRRE---EEERQRHAEHHARREHDSGG 926
+V E +KL +R + ++ R+A+ R ++++ R RE E+ER+R E R
Sbjct: 784 FVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQ 843
Query: 927 REEARAEGSGLDP 939
A E L P
Sbjct: 844 EGRAPVECPSLGP 856
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 61.6 bits (148), Expect = 4e-09
Identities = 80/333 (24%), Positives = 112/333 (33%), Gaps = 54/333 (16%)
Query: 895 HRYQQQQRRRREEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKASAKAKGST 954
H QQQQ+++++++++Q+ +HH G EG SS A A +
Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGG------SSHHAHPYAMSPS 535
Query: 955 AGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSP 1014
G P P P L P++ + Q P SS +SS + G+ + P P+Q P
Sbjct: 536 LGSLRP-YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP 594
Query: 1015 TGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQ-A 1073
G+ + F P S A S+ AG + A
Sbjct: 595 QGA--------PYPFPPVPTVTTSSA---------------TLSTVIATVASSPAGYKTA 631
Query: 1074 RPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPP 1133
P G P G R G A + P +GT G + P P
Sbjct: 632 SPPGPPPYG-KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSP 690
Query: 1134 PPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPP--APQPLPGD 1191
P P PP P+G L + PP A A PP A Q
Sbjct: 691 TVGPGPLPPAGPSG--------------------LPSLPPPPAAPASGPPLSATQIKQEP 730
Query: 1192 ASFYSLPPPPLPPTSDPLETPAPSPSPSPSPQA 1224
A Y P P+PP P P PS + Q+
Sbjct: 731 AEEYETPESPVPPARSPSPPPKVVDVPSHASQS 763
Score = 42.0 bits (97), Expect = 0.004
Identities = 80/362 (22%), Positives = 121/362 (33%), Gaps = 54/362 (14%)
Query: 872 AEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRREEEERQRHAEHHARREHDSGGREEAR 931
+EE+++ E + A K+ + + Q+ R + + + + S +
Sbjct: 73 SEEISESESEETNAPKKTKTE-------QELPRPQSPSDLDSLDGRSLNDDGSSDPRDID 125
Query: 932 AEGSGLDPATSSEKASAKAKGSTAG-GHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLS 990
+ P+ S + S++G GP RP P L P+ + P Q +
Sbjct: 126 QDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP--QPPDSTPRQPE--- 180
Query: 991 SGATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFH 1050
A+ P P+ +PTG + + P +R +PP
Sbjct: 181 -------------ASFEPHPSVTPTGYHAPM---------EPPTSRMFQAPPGAPPPH-- 216
Query: 1051 AGKLFPFGGT----RAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAP--R 1104
+L+P GGT P GG A G P+ G + P+ + + AP +
Sbjct: 217 -PQLYP-GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274
Query: 1105 PEEEGSGTALAPVGAPALRTRRSRSPAPPPPM--PLPRPPTPPAGCWQWDGPWGCGGEGA 1162
P G P P PPPP PL P G G G
Sbjct: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL----GAQPLPGHLP 330
Query: 1163 APR-QALAAAECPPCAMAGPPPAPQP--LPGDASFYSLPPPPLPPTSDPLETPAPSPSPS 1219
+P PP GP AP P LP +S PP P +S + A S S S
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Query: 1220 PS 1221
S
Sbjct: 391 SS 392
Score = 41.6 bits (96), Expect = 0.005
Identities = 70/316 (22%), Positives = 113/316 (35%), Gaps = 43/316 (13%)
Query: 947 SAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATT 1006
S A G GG P K P +P+++ P ++SS +AA + +++
Sbjct: 331 SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Query: 1007 RPPPAQSPTGSDTRLPAFL-SFKFLKS------------PETRRDSERSHSPPKAFHAGK 1053
+ SP + LP++ SF S P + S PP G+
Sbjct: 391 SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGR 450
Query: 1054 LFPFGGTRAEPG----SNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEA------- 1102
L + A PG S GA A P + + Q+ + ++ +
Sbjct: 451 LL--ANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508
Query: 1103 -------PRPEEEGSGTALAPVG-APALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGP 1154
P P E GS P +P+L + R P PP P LP P + + + GP
Sbjct: 509 PPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR---PYPPGPAHLPPPHSQVS--YSQAGP 563
Query: 1155 WGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAP 1214
G ++ + + PC+ P+P P A + P P + +S L T
Sbjct: 564 NGPPVSSSSNSSSSTSQGSYPCSH----PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIA 619
Query: 1215 SPSPSPSPQAVCWPSG 1230
+ + SP+ P G
Sbjct: 620 TVASSPAGYKTASPPG 635
Score = 38.1 bits (87), Expect = 0.052
Identities = 56/235 (23%), Positives = 76/235 (32%), Gaps = 36/235 (15%)
Query: 994 TSSLAAAGAGATTRPP--PAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHA 1051
T+ ++ + +GA+ PP P +P G P + H P
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNL------------PSAPPPANFPHVTPNLPPP 304
Query: 1052 GKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSG 1111
L P A P G G Q P PS + G P PE+ G
Sbjct: 305 PALRPLNNASASPP--GLGAQPLPGHLPSPHAMGQGMGGL----------PPGPEK---G 349
Query: 1112 TALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAA- 1170
LAP +L S +PAPP P + A QAL +
Sbjct: 350 PTLAP-SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSY 408
Query: 1171 --AECPPCAMA---GPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPSPSP 1220
+ PP +++ PP QP + +S PPP PP L P P P
Sbjct: 409 PHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFP 463
Score = 32.3 bits (72), Expect = 2.9
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 870 WVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRRE---EEERQRHAEHHARREHDSGG 926
+V E +KL +R + ++ R+A+ R ++++ R RE E+ER+R E R
Sbjct: 784 FVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQ 843
Query: 927 REEARAEGSGLDP 939
A E L P
Sbjct: 844 EGRAPVECPSLGP 856
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 61.6 bits (148), Expect = 4e-09
Identities = 54/171 (31%), Positives = 61/171 (35%), Gaps = 44/171 (25%)
Query: 1085 RVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTP 1144
RV G + A ++ PR AP GAPA + + APPP P PP P
Sbjct: 84 RVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAA----AAAAAPPPT---PAPPPP 136
Query: 1145 PAGCWQWDGPWGCGGEGAAPRQALAAAECPP--------------CAMAGPPPAPQPLPG 1190
PA P APR A AAA PP +A PPPAP P
Sbjct: 137 PA-------PVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPA 189
Query: 1191 DASFYS---------------LPPPPLPPTS-DPLETPAPSPSPSPSPQAV 1225
A LPPPP PP + P P P P P AV
Sbjct: 190 VAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAV 240
Score = 53.9 bits (128), Expect = 9e-07
Identities = 60/192 (31%), Positives = 79/192 (41%), Gaps = 48/192 (25%)
Query: 536 GGSGGGGRRCLSGGCGAPEEEEEAAL--VERRRAG-----EGGEEGDGPP---------- 578
GGSGG G R G EEE AA +ER R G G G PP
Sbjct: 259 GGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSK 318
Query: 579 -GGKEEDEDDEEEEDEEEEEDEEEGEEGGLLDCGLRLKKVSFAERGAGRR-------RPG 630
GG+E + EEEED++E+EDEE+ G +V ++R AG + R
Sbjct: 319 RGGEERVLEKEEEEDDDEDEDEEDDVSEG--------SEVPESDRPAGAQHHQLNGERGP 370
Query: 631 PSPEALLEEGSPTMVEKGLEPGVFTLAEEDDEAEG-APGSPERE--PPAILFRRAGGEGR 687
S + ++E +P +G DE G APGS R+ A + + G
Sbjct: 371 QSAKERVKEWTPCGPHQG-----------QDEGRGPAPGSGTRQVFSMAAMNKEGGTASV 419
Query: 688 DQGPDGGPDPEP 699
GPD P P P
Sbjct: 420 ATGPD-SPSPVP 430
Score = 45.4 bits (106), Expect = 3e-04
Identities = 45/144 (31%), Positives = 52/144 (36%), Gaps = 26/144 (18%)
Query: 1061 RAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGA- 1119
RA G+ A A P TP+ P A A APR + +P A
Sbjct: 113 RAPRGAPAAAAAAAPPPTPAPPPP------PAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166
Query: 1120 PALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMA 1179
P R +R+ A PPP P P P G AP A+AA E PP
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPA-----------GPRRAPPPAVAARE-PPL--- 211
Query: 1180 GPPPAPQPLPGDASFYSLPPPPLP 1203
PPP P P PPPP P
Sbjct: 212 -PPPPQPPAPPQQQ---QPPPPQP 231
Score = 42.4 bits (98), Expect = 0.003
Identities = 50/203 (24%), Positives = 61/203 (30%), Gaps = 89/203 (43%)
Query: 992 GATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHA 1051
GA ++ AAA T PPP +P + +P +A
Sbjct: 117 GAPAAAAAAAPPPTPAPPPPPAPVA-------------------------AAAPARA--- 148
Query: 1052 GKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSG 1111
P + A A P P+ R QR+ P L AP P
Sbjct: 149 ------------PRAAAAAATAPPSPGPAQPGPRAQRAAP--------LAAPPP------ 182
Query: 1112 TALAPVGAPALRTRRSRSPAPPPPM-----PLPRPPTPPAGCWQWDGPWGCGGEGAAPRQ 1166
AP PA+ APPP + PLP PP PPA
Sbjct: 183 ---APAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA-------------------- 219
Query: 1167 ALAAAECPPCAMAGPPPAPQPLP 1189
PP PPP PQP P
Sbjct: 220 -------PPQQQQPPPPQPQPPP 235
Score = 31.6 bits (70), Expect = 4.9
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 1181 PPPAPQPLPGDASFYSLPPPPLP-PTSDPLETPAPSPSPSPSPQAVCWP 1228
PP AP+ P A+ + PP P P P P+ AP+ +P + A P
Sbjct: 111 PPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 61.2 bits (147), Expect = 6e-09
Identities = 84/308 (27%), Positives = 106/308 (34%), Gaps = 65/308 (21%)
Query: 939 PATSSEKASAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLA 998
P S K + K G +A G P G L A + P + ++ G T
Sbjct: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGG----FPVLRPAGQRDVAGGKT---- 122
Query: 999 AAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKLFPFG 1058
G G +R P + P K + P S R + +A A + P
Sbjct: 123 --GQGPGSRAPSPRLPN------------KTISGPLIPPASPRLGNTSEAHGAARTAP-- 166
Query: 1059 GTRAEPGSN-GAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPV 1117
P N A P P + S P+ L + P P +G+ PV
Sbjct: 167 -----PRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPL---VSPPGPLTKGN----LPV 214
Query: 1118 GAPALRTRRSRSPAPPPPMPLPRPPT---------------------PPAGCWQWDGPWG 1156
AP + P PPPP P P PP PP G G
Sbjct: 215 VAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
Query: 1157 CGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSP 1216
E A+P Q A+ PP A PPP P P + SLP PPLP + ETP P P
Sbjct: 275 LKAEPASPAQD---AQEPP---APPPPLP-PYASCSPRASLPAPPLPGVNSSSETPPPLP 327
Query: 1217 SPSPSPQA 1224
SPS QA
Sbjct: 328 PKSPSFQA 335
Score = 43.9 bits (102), Expect = 0.001
Identities = 48/185 (25%), Positives = 69/185 (37%), Gaps = 45/185 (24%)
Query: 1084 SRVQRSGPVDEALAEELEAPR-PEEEGSGTA-------------LAPVGAPALRTRRSR- 1128
+R+++ +++ A ++E+ + +EG G+A L G P LR R
Sbjct: 57 TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116
Query: 1129 -----------SPAPPPPMP---LPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECP 1174
S AP P +P + P PPA + G AP + A P
Sbjct: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP 176
Query: 1175 PCAMAGPPPAPQPLPGDASFYS---LPP------------PPLPPTSDPLETPAPSPSPS 1219
P PPP P PLP + + PP PP+P P P P P+P
Sbjct: 177 PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP-PPPPPPPTPP 235
Query: 1220 PSPQA 1224
P P A
Sbjct: 236 PLPPA 240
Score = 35.4 bits (80), Expect = 0.34
Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 1178 MAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPS 1215
M PPP P PLP PPPP PP++ P+ T S
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPP-PPSAPPVSTDTSS 37
Score = 34.3 bits (77), Expect = 0.75
Identities = 13/23 (56%), Positives = 14/23 (60%)
Query: 1198 PPPPLPPTSDPLETPAPSPSPSP 1220
PPPPLPP PL P P P +P
Sbjct: 7 PPPPLPPPPPPLGAPPPPPPSAP 29
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 61.2 bits (147), Expect = 6e-09
Identities = 51/145 (35%), Positives = 59/145 (40%), Gaps = 25/145 (17%)
Query: 1082 GSSRVQRSGPVDEALAEELEAP--RPEEEGSGTALAPVGAPALRTRRSRSPAP----PPP 1135
G R+ R GP D E L P + T P G+P+ + PAP PPP
Sbjct: 487 GLIRILR-GPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPP 545
Query: 1136 MPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFY 1195
PLP P+P +AP QA P PPPAP PLPGD
Sbjct: 546 PPLPGLPSPQEA------------PPSAPPQAPPLPGSPE-----PPPAP-PLPGDLPPP 587
Query: 1196 SLPPPPLPPTSDPLETPAPSPSPSP 1220
PPPP P T P+ P P P P P
Sbjct: 588 PPPPPPPPGTDGPVPPPPPPPPPPP 612
Score = 48.5 bits (114), Expect = 4e-05
Identities = 40/120 (33%), Positives = 45/120 (37%), Gaps = 11/120 (9%)
Query: 1091 PVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMP-LPRPPTPPAGCW 1149
PV A +AP P + P APA +P PPPP+P LP P P
Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPS--PDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAP 562
Query: 1150 QWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPG-DASFYSLPPPPLPPTSDP 1208
P G P + PP PPP P P PG D PPPP PP P
Sbjct: 563 PQAPP--LPGSPEPPPAPPLPGDLPP-----PPPPPPPPPGTDGPVPPPPPPPPPPPGGP 615
Score = 35.4 bits (80), Expect = 0.34
Identities = 50/186 (26%), Positives = 62/186 (33%), Gaps = 24/186 (12%)
Query: 1003 GATTRPP-PAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAFHAGKL-----FP 1056
GA+ RPP P ++P + TR P+ L K ++ E + P A L P
Sbjct: 454 GASRRPPEPEKAPPAAPTR-PSALELK-VEELEEKGLIRILRGPGDAVSIEILPVAVATP 511
Query: 1057 FGGTRAEPG-------------SNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEA- 1102
GG PG + A G A P P G Q + P A L
Sbjct: 512 SGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571
Query: 1103 --PRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGE 1160
P P G P P PPPP P P P PP + D G G +
Sbjct: 572 PEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVK 631
Query: 1161 GAAPRQ 1166
P Q
Sbjct: 632 AKKPIQ 637
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 60.8 bits (146), Expect = 8e-09
Identities = 55/191 (28%), Positives = 67/191 (35%), Gaps = 30/191 (15%)
Query: 1058 GGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPV 1117
GG G G GG +P G Q GP+ P P + G + P
Sbjct: 14 GGFHRRGGGGGRGG-LHDFRSPPPGMGLNQNRGPM---------GPGPGQSGPKPPIPPP 63
Query: 1118 GA--------PALRTRRSRSPAPPPPMPLP----RPPTPPAGCWQ---WDGPWGCGGEGA 1162
P + P PPP P P +PP PP + GP G G+
Sbjct: 64 PPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGS 123
Query: 1163 APRQALAAAECPPCAMAGPP-----PAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPS 1217
AP + +A P PP P P P P S PPP PP+S TP +
Sbjct: 124 APPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGG 183
Query: 1218 PSPSPQAVCWP 1228
P P P AV P
Sbjct: 184 PPPPPAAVPGP 194
Score = 47.4 bits (111), Expect = 9e-05
Identities = 43/153 (28%), Positives = 53/153 (34%), Gaps = 21/153 (13%)
Query: 1072 QARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPA 1131
Q +P P S V GP A + + P + A P + +P
Sbjct: 96 QQQPPPPPQDSSKPVVAQGP---GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPT 152
Query: 1132 PPPPM----PLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAP-- 1185
PPP + P PPTPP+ G P QA PP A+ GP P P
Sbjct: 153 PPPAVTSAPPGAPPPTPPSS-----------GVPTTPPQA-GGPPPPPAAVPGPGPGPKQ 200
Query: 1186 QPLPGDASFYSLPPPPLPPTSDPLETPAPSPSP 1218
P PG +P P P L TP P P
Sbjct: 201 GPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKP 233
Score = 37.0 bits (84), Expect = 0.12
Identities = 45/158 (28%), Positives = 61/158 (38%), Gaps = 19/158 (12%)
Query: 873 EEMAKLE-YQRREAFKRHERQAQHRYQQQQRRRREEEE--RQRHAEHHARREHDSGGREE 929
EE+ ++E +E KR E Q + Q+++RRRREEE RQR E RR+ REE
Sbjct: 544 EELRRMEELHNQEMQKRKEMQLR---QEEERRRREEEMMIRQREMEEQMRRQ-----REE 595
Query: 930 ARAEGSGLDPATSSEK---ASAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQG 986
+ + +DP + A G G G + P G + G
Sbjct: 596 SYSRMGYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSG 655
Query: 987 KFLSSG-ATSSLAAAGAGATTRPPPAQSPTGSDTRLPA 1023
+ S T GAG P Q P G PA
Sbjct: 656 SMMGSDMRTERFGQGGAG----PVGGQGPRGMGPGTPA 689
Score = 30.8 bits (68), Expect = 8.3
Identities = 39/155 (25%), Positives = 49/155 (31%), Gaps = 22/155 (14%)
Query: 990 SSGATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRRDSERSHSPPKAF 1049
S+ SS A T+ PP P + T PA S P T S +PP+A
Sbjct: 123 SAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAG 182
Query: 1050 -----HAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPR 1104
A P G + PG G G P G G + G P+
Sbjct: 183 GPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPG----------GHPK 232
Query: 1105 PEEEGSGTALAPVGA----PALRTRRSRSPAPPPP 1135
P G G P G P + + P P P
Sbjct: 233 PPHRGGG---EPRGGRQHHPPYHQQHHQGPPPGGP 264
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,686,765
Number of Sequences: 37866
Number of extensions: 4114363
Number of successful extensions: 95694
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1006
Number of HSP's successfully gapped in prelim test: 1985
Number of HSP's that attempted gapping in prelim test: 38419
Number of HSP's gapped (non-prelim): 32564
length of query: 1232
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1118
effective length of database: 13,930,794
effective search space: 15574627692
effective search space used: 15574627692
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.