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Search of human proteins with 54873624
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54873624 eukaryotic translation initiation factor 2A [Homo
sapiens]
(585 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54873624 eukaryotic translation initiation factor 2A [Homo sa... 1207 0.0
gi|33239445 eukaryotic translation initiation factor 3, subunit ... 89 1e-17
gi|83367072 eukaryotic translation initiation factor 3, subunit ... 89 1e-17
gi|219803946 within bgcn homolog isoform 2 [Homo sapiens] 69 9e-12
gi|14150139 within bgcn homolog isoform 1 [Homo sapiens] 69 2e-11
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 45 2e-04
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 44 5e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 41 0.003
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 41 0.003
gi|189571683 WD repeat, sterile alpha motif and U-box domain con... 41 0.003
gi|189571681 WD repeat, sterile alpha motif and U-box domain con... 41 0.003
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 40 0.008
gi|4885371 H1 histone family, member 0 [Homo sapiens] 39 0.013
gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens] 39 0.017
gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens] 39 0.017
gi|104526627 triadin [Homo sapiens] 39 0.017
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 38 0.023
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 38 0.023
gi|156104908 myosin heavy chain 6 [Homo sapiens] 38 0.030
gi|23199987 WD repeat domain 5B [Homo sapiens] 38 0.030
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 37 0.050
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 37 0.050
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 37 0.050
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 37 0.050
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 37 0.050
gi|50843827 activating molecule in beclin-1-regulated autophagy ... 37 0.066
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 37 0.066
gi|42558250 membrane component chromosome 11 surface marker 1 is... 37 0.066
gi|42734503 membrane component chromosome 11 surface marker 1 is... 37 0.066
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 36 0.086
>gi|54873624 eukaryotic translation initiation factor 2A [Homo
sapiens]
Length = 585
Score = 1207 bits (3124), Expect = 0.0
Identities = 585/585 (100%), Positives = 585/585 (100%)
Query: 1 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN 60
MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN
Sbjct: 1 MAPSTPLLTVRGSEGLYMVNGPPHFTESTVFPRESGKNCKVCIFSKDGTLFAWGNGEKVN 60
Query: 61 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL 120
IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL
Sbjct: 61 IISVTNKGLLHSFDLLKAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCL 120
Query: 121 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ 180
KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ
Sbjct: 121 KSFIQKKMQNWCPSWSEDETLCARNVNNEVHFFENNNFNTIANKLHLQKINDFVLSPGPQ 180
Query: 181 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS 240
PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS
Sbjct: 181 PYKVAVYVPGSKGAPSFVRLYQYPNFAGPHAALANKSFFKADKVTMLWNKKATAVLVIAS 240
Query: 241 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT 300
TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT
Sbjct: 241 TDVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKAT 300
Query: 301 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS 360
IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS
Sbjct: 301 IFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS 360
Query: 361 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI 420
TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI
Sbjct: 361 TYFAWCPDGEHILTATCAPRLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQPFLDGI 420
Query: 421 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL 480
FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL
Sbjct: 421 FPAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPL 480
Query: 481 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL 540
SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL
Sbjct: 481 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL 540
Query: 541 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI 585
KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI
Sbjct: 541 KKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELEDLELGI 585
>gi|33239445 eukaryotic translation initiation factor 3, subunit 9
eta, 116kDa [Homo sapiens]
Length = 814
Score = 88.6 bits (218), Expect = 1e-17
Identities = 91/396 (22%), Positives = 161/396 (40%), Gaps = 39/396 (9%)
Query: 31 FPRESGKNCKVCIFSKDGTLFAWGNGEKVNIISVTNKGLLHSFDLLKAVCLEFSPKNTVL 90
+ R S K + F + G + WG + I +++G+ ++FSP L
Sbjct: 339 YVRWSPKGTYLATFHQRG-IALWGGEKFKQIQRFSHQGVQ---------LIDFSPCERYL 388
Query: 91 ATWQPYTTSKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNW-CPSWSEDETLCARNVNNE 149
T+ P ++D I ++D+ TG + F + +W WS D AR +
Sbjct: 389 VTFSPLMDTQDDPQAII---IWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDT 445
Query: 150 VHFFENNNFNTIANK-LHLQKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFAG 208
+ +E + + K L + I DF SPG +A +VP K P+ V L Q P
Sbjct: 446 LSIYETPSMGLLDKKSLKISGIKDFSWSPGGNI--IAFWVPEDKDIPARVTLMQLPT--- 500
Query: 209 PHAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAV- 267
+ ++ F + W K + V VD+T G T I E V
Sbjct: 501 -RQEIRVRNLFNVVDCKLHWQKNGDYLCV----KVDRTPKGTQGVVTNFEIFRMREKQVP 555
Query: 268 ---VQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATIF-----NLKCDPVFDFGTGPRNA 319
V++ + I W + ++F ++G P + F N K + + F N
Sbjct: 556 VDVVEMKET--IIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANT 613
Query: 320 AYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAP 379
++SP G +VLAG ++ G + D + +++ ++ W P G +++T+
Sbjct: 614 IFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWW 673
Query: 380 RLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQP 415
+V+N Y +W + G +L K + Q+ W+P
Sbjct: 674 SHKVDNAYWLWTFQGRLLQK---NNKDRFCQLLWRP 706
>gi|83367072 eukaryotic translation initiation factor 3, subunit 9
eta, 116kDa [Homo sapiens]
Length = 814
Score = 88.6 bits (218), Expect = 1e-17
Identities = 91/396 (22%), Positives = 161/396 (40%), Gaps = 39/396 (9%)
Query: 31 FPRESGKNCKVCIFSKDGTLFAWGNGEKVNIISVTNKGLLHSFDLLKAVCLEFSPKNTVL 90
+ R S K + F + G + WG + I +++G+ ++FSP L
Sbjct: 339 YVRWSPKGTYLATFHQRG-IALWGGEKFKQIQRFSHQGVQ---------LIDFSPCERYL 388
Query: 91 ATWQPYTTSKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNW-CPSWSEDETLCARNVNNE 149
T+ P ++D I ++D+ TG + F + +W WS D AR +
Sbjct: 389 VTFSPLMDTQDDPQAII---IWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDT 445
Query: 150 VHFFENNNFNTIANK-LHLQKINDFVLSPGPQPYKVAVYVPGSKGAPSFVRLYQYPNFAG 208
+ +E + + K L + I DF SPG +A +VP K P+ V L Q P
Sbjct: 446 LSIYETPSMGLLDKKSLKISGIKDFSWSPGGNI--IAFWVPEDKDIPARVTLMQLPT--- 500
Query: 209 PHAALANKSFFKADKVTMLWNKKATAVLVIASTDVDKTGASYYGEQTLHYIATNGESAV- 267
+ ++ F + W K + V VD+T G T I E V
Sbjct: 501 -RQEIRVRNLFNVVDCKLHWQKNGDYLCV----KVDRTPKGTQGVVTNFEIFRMREKQVP 555
Query: 268 ---VQLPKNGPIYDVVWNSSSTEFCAVYGFMPAKATIF-----NLKCDPVFDFGTGPRNA 319
V++ + I W + ++F ++G P + F N K + + F N
Sbjct: 556 VDVVEMKET--IIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANT 613
Query: 320 AYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDSTYFAWCPDGEHILTATCAP 379
++SP G +VLAG ++ G + D + +++ ++ W P G +++T+
Sbjct: 614 IFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWW 673
Query: 380 RLRVNNGYKIWHYTGSILHKYDVPSNAELWQVSWQP 415
+V+N Y +W + G +L K + Q+ W+P
Sbjct: 674 SHKVDNAYWLWTFQGRLLQK---NNKDRFCQLLWRP 706
>gi|219803946 within bgcn homolog isoform 2 [Homo sapiens]
Length = 203
Score = 69.3 bits (168), Expect = 9e-12
Identities = 57/201 (28%), Positives = 93/201 (46%), Gaps = 31/201 (15%)
Query: 415 PFLDGIFPAKTITYQAVPSEVPNEEPKVATAYRP----PALRNKPITNSKLHEEEPPQNM 470
P++ K I P ++ +V Y P P NK + K E PP +
Sbjct: 4 PYVTDETGGKYIASTQRPDGTWRKQRRVKEGYVPQEEVPVYENKYVKFFKSKPELPP-GL 62
Query: 471 KPQS----------GNDKPLSKTALKNQRKHEAKKAAKQEARSDK------SPDLAPTPA 514
P++ G + LSKTA +N ++ E ++ +++ ++ L T
Sbjct: 63 SPEATAPVTPSRPEGGEPGLSKTAKRNLKRKEKRRQQQEKGEAEALSRTLDKVSLEETAQ 122
Query: 515 PQSTPRNTVSQSISGDPEID--------KKIKNLKKKLKAIEQLKEQAATGK--QLEKNQ 564
S P+ + + + + D KKIKNLKKKL+ +E+L+++ G+ Q K Q
Sbjct: 123 LPSAPQGSRAAPTAASDQPDSAATTEKAKKIKNLKKKLRQVEELQQRIQAGEVSQPSKEQ 182
Query: 565 LEKIQKETALLQELEDLELGI 585
LEK+ + AL +ELEDLELG+
Sbjct: 183 LEKLARRRALEEELEDLELGL 203
>gi|14150139 within bgcn homolog isoform 1 [Homo sapiens]
Length = 204
Score = 68.6 bits (166), Expect = 2e-11
Identities = 54/184 (29%), Positives = 88/184 (47%), Gaps = 31/184 (16%)
Query: 432 PSEVPNEEPKVATAYRP----PALRNKPITNSKLHEEEPPQNMKPQS----------GND 477
P ++ +V Y P P NK + K E PP + P++ G +
Sbjct: 22 PDGTWRKQRRVKEGYVPQEEVPVYENKYVKFFKSKPELPP-GLSPEATAPVTPSRPEGGE 80
Query: 478 KPLSKTALKNQRKHEAKKAAKQEARSDK------SPDLAPTPAPQSTPRNTVSQSISGDP 531
LSKTA +N ++ E ++ +++ ++ L T S P+ + + +
Sbjct: 81 PGLSKTAKRNLKRKEKRRQQQEKGEAEALSRTLDKVSLEETAQLPSAPQGSRAAPTAASD 140
Query: 532 EID--------KKIKNLKKKLKAIEQLKEQAATGK--QLEKNQLEKIQKETALLQELEDL 581
+ D KKIKNLKKKL+ +E+L+++ G+ Q K QLEK+ + AL +ELEDL
Sbjct: 141 QPDSAATTEKAKKIKNLKKKLRQVEELQQRIQAGEVSQPSKEQLEKLARRRALEEELEDL 200
Query: 582 ELGI 585
ELG+
Sbjct: 201 ELGL 204
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 15/148 (10%)
Query: 447 RPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKS 506
+PP L KP T + N+ P+ + +PLSK A K++ +E K A K +A +D
Sbjct: 1727 QPPYLDAKPPTPGASFSQAE-SNVDPEPDSTQPLSKPAQKSEEANEPK-AEKPDATADAE 1784
Query: 507 PDL--APTPAPQSTPRNTVSQSISGDPEIDKKIK--NLKKKLK-----AIEQLKEQAATG 557
PD AP+S P S+ + DP + K K N K+ K A + E+ T
Sbjct: 1785 PDANQKAEAAPESQP--PASEDLEVDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEKPVTR 1842
Query: 558 K--QLEKNQLEKIQKETALLQELEDLEL 583
K ++++ +L++ Q+L +L++
Sbjct: 1843 KSERIDREKLKRSNSPRGEAQKLLELKM 1870
Score = 30.8 bits (68), Expect = 3.6
Identities = 31/146 (21%), Positives = 57/146 (39%), Gaps = 31/146 (21%)
Query: 447 RPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLS-KTAL---------KNQRKHEA--- 493
RPP R + + +EP + +KP G P S KTA KN+ K +A
Sbjct: 1952 RPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNEPKVDATRP 2011
Query: 494 ------------------KKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDK 535
KAA++EA S++ D ++ P + + P +K
Sbjct: 2012 EATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPEK 2071
Query: 536 KIKNLKKKLKAIEQLKEQAATGKQLE 561
K+ + + + +++A+ K ++
Sbjct: 2072 NSKSKRGRSRNSRLAVDKSASLKNVD 2097
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 43.5 bits (101), Expect = 5e-04
Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 25/160 (15%)
Query: 430 AVPSEVPNEEPK-------------VATAYRPPALRNKPITNSKLHEEEPP----QNMKP 472
A+PS+ +++P +A + + P +++ SK E++ P ++ KP
Sbjct: 694 ALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKP 753
Query: 473 QSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTP-------RNTVSQ 525
+ K K K ++K + KKA + +P AP PAP P T +Q
Sbjct: 754 KKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTDECEDAKTEAQ 813
Query: 526 SISGDPE-IDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQ 564
D E D+ K+ K K K + KE+ GK+ K Q
Sbjct: 814 GEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKSKKQ 853
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/197 (24%), Positives = 80/197 (40%), Gaps = 48/197 (24%)
Query: 422 PAKTITYQAVPS-EVPN-EEP---------KVATAYRPPALRNKPITNSKL--HEEEPPQ 468
P KT T +V EVP+ EEP K AT +P A + K + E++ +
Sbjct: 593 PIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEE 652
Query: 469 NMKPQSGNDKPLSKTALKNQ---RKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQ 525
KP+ K KT +K + +K E KK K+E + ++ + + TP V +
Sbjct: 653 KEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKE-PKKEVKKETPPKEVKK 711
Query: 526 SISGDP--EIDKKIKNLKKKLKAIEQ-----------------------------LKEQA 554
+ + E+ K+ K KK++K + + K+
Sbjct: 712 EVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSV 771
Query: 555 ATGKQLEKNQLEKIQKE 571
A GK EK +++ I+KE
Sbjct: 772 AAGKPKEKGKIKVIKKE 788
Score = 34.7 bits (78), Expect = 0.25
Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 6/130 (4%)
Query: 434 EVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEA 493
E P +E + K ++ +E PP+ +K + ++ + + K E
Sbjct: 673 EKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEI 732
Query: 494 KKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSI------SGDPEIDKKIKNLKKKLKAI 547
KK K +S A PA +S+ +G P+ KIK +KK+ KA
Sbjct: 733 KKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAA 792
Query: 548 EQLKEQAATG 557
E + TG
Sbjct: 793 EAVAAAVGTG 802
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 15/124 (12%)
Query: 42 CIFSKDGTLFAWGNGEKVNIISVTN-KGLLHSF--DLLKAVCLEFSPKNTVLATWQPYTT 98
C FS DG + G+ +K I+ TN + +LH+ F+P +LA T
Sbjct: 245 CAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLA-----TG 299
Query: 99 SKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNWCPSWSEDET---LCARNVNNEVHFFEN 155
S D T N+ +D++T C + +++ + WSE++ LCA+++ + V F+
Sbjct: 300 SMDKTV---NIWQFDLET-LCQARRTEHQLKQFTEDWSEEDVSTWLCAQDLKDLVGIFKM 355
Query: 156 NNFN 159
NN +
Sbjct: 356 NNID 359
>gi|189571683 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 15/124 (12%)
Query: 42 CIFSKDGTLFAWGNGEKVNIISVTN-KGLLHSF--DLLKAVCLEFSPKNTVLATWQPYTT 98
C FS DG + G+ +K I+ TN + +LH+ F+P +LA T
Sbjct: 245 CAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLA-----TG 299
Query: 99 SKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNWCPSWSEDET---LCARNVNNEVHFFEN 155
S D T N+ +D++T C + +++ + WSE++ LCA+++ + V F+
Sbjct: 300 SMDKTV---NIWQFDLET-LCQARRTEHQLKQFTEDWSEEDVSTWLCAQDLKDLVGIFKM 355
Query: 156 NNFN 159
NN +
Sbjct: 356 NNID 359
>gi|189571681 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 15/124 (12%)
Query: 42 CIFSKDGTLFAWGNGEKVNIISVTN-KGLLHSF--DLLKAVCLEFSPKNTVLATWQPYTT 98
C FS DG + G+ +K I+ TN + +LH+ F+P +LA T
Sbjct: 245 CAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLA-----TG 299
Query: 99 SKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNWCPSWSEDET---LCARNVNNEVHFFEN 155
S D T N+ +D++T C + +++ + WSE++ LCA+++ + V F+
Sbjct: 300 SMDKTV---NIWQFDLET-LCQARRTEHQLKQFTEDWSEEDVSTWLCAQDLKDLVGIFKM 355
Query: 156 NNFN 159
NN +
Sbjct: 356 NNID 359
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 39.7 bits (91), Expect = 0.008
Identities = 40/160 (25%), Positives = 70/160 (43%), Gaps = 9/160 (5%)
Query: 423 AKTITYQAVPSEVPNEEPKVATAYRPPA-LRNKPITNSKLHEEEPPQNMKPQSGNDKPLS 481
AK+ + V S + P A P + K S + EEE PQ +K + K
Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE 844
Query: 482 KTALKNQRKHEAKKAAKQEARSDKSP----DLAPTPAPQSTPRNTVSQSISGDPEIDKKI 537
+ A + E K + K+EA ++P + PA + P+ + ++ + E KK+
Sbjct: 845 EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK-PKESKVEAKKEEAEDKKKV 903
Query: 538 KNLKKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQE 577
+K+ A ++KE A K EK ++ K + + A +E
Sbjct: 904 PTPEKEAPAKVEVKEDA---KPKEKTEVAKKEPDDAKAKE 940
Score = 36.6 bits (83), Expect = 0.066
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 5/147 (3%)
Query: 423 AKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEE--EPPQNMKPQSGNDKPL 480
AK+ + S + P+ A P +++ S EE PP+ P+ K
Sbjct: 516 AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 481 SKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNL 540
++ + K AK+ AK A + KSP+ A +P + + +++ S E K +
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEA-KSPEKAKSPVKEEA--KSPAEAKSPVKEEAKSPAEV 632
Query: 541 KKKLKAIEQLKEQAATGKQLEKNQLEK 567
K KA KE+A + ++ + + E+
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEE 659
Score = 32.7 bits (73), Expect = 0.95
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 14/151 (9%)
Query: 438 EEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAA 497
EE K + P ++ + T K + P+ +KT + + EAK A
Sbjct: 714 EEAKSPEKAKSP-VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL--DVKSPEAKTPA 770
Query: 498 KQEARS--DKSPDLAPTP------APQSTPRNTVSQSISGDPEIDKKIKNLKKKLKAIEQ 549
K+EARS DK P+ A +P +P+ + + + EI KK + +K +K E+
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK-EEVKSPVK--EE 827
Query: 550 LKEQAATGKQLEKNQLEKIQKETALLQELED 580
K Q K+ K E+ T +E +D
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Score = 30.8 bits (68), Expect = 3.6
Identities = 37/169 (21%), Positives = 66/169 (39%), Gaps = 16/169 (9%)
Query: 422 PAKTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLS 481
P K + P+ EE K + P K K+ E++ P KP+ +
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAP---KKEAPKPKVEEKKEPAVEKPKESKVEAKK 894
Query: 482 KTALKN------QRKHEAKKAAKQEARSDKSPDLA---PTPAPQSTPRNTVSQSISGDPE 532
+ A +++ AK K++A+ + ++A P A P + + +
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954
Query: 533 IDKKIKNLKK---KLKAIEQLKEQAAT-GKQLEKNQLEKIQKETALLQE 577
D K + KK K K + KE T K+ K + EK +K ++ Q+
Sbjct: 955 KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQK 1003
>gi|4885371 H1 histone family, member 0 [Homo sapiens]
Length = 194
Score = 38.9 bits (89), Expect = 0.013
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 476 NDKPLSKTALKNQRKHEAKKAA--KQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEI 533
+D+P A K +K E KK A K+ ++ K+ APT P++TP + ++ P+
Sbjct: 98 SDEPKKSVAFKKTKK-EIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKK 156
Query: 534 DKKIKNLKKK 543
KK K +K K
Sbjct: 157 AKKPKTVKAK 166
>gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]
Length = 1127
Score = 38.5 bits (88), Expect = 0.017
Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
Query: 486 KNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDK-------KIK 538
+ +R+ K A Q S QST + S S + + I+ KI+
Sbjct: 75 EEEREGNMKSAKPQVNHSQHGESQRALSPLQSTLSSAASPSQAYETYIENGLICLKHKIR 134
Query: 539 NLKKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELE 579
N++KK +E K++ +G+ L +QLE ++K +L LE
Sbjct: 135 NIEKKKLKLEDYKDRLKSGEHLNPDQLEAVEKYEEVLHNLE 175
>gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]
Length = 1077
Score = 38.5 bits (88), Expect = 0.017
Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
Query: 486 KNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDK-------KIK 538
+ +R+ K A Q S QST + S S + + I+ KI+
Sbjct: 75 EEEREGNMKSAKPQVNHSQHGESQRALSPLQSTLSSAASPSQAYETYIENGLICLKHKIR 134
Query: 539 NLKKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELE 579
N++KK +E K++ +G+ L +QLE ++K +L LE
Sbjct: 135 NIEKKKLKLEDYKDRLKSGEHLNPDQLEAVEKYEEVLHNLE 175
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 38.5 bits (88), Expect = 0.017
Identities = 29/134 (21%), Positives = 60/134 (44%), Gaps = 6/134 (4%)
Query: 454 KPITNSK--LHEEE---PPQNMKPQSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKSPD 508
KP + K +H+++ P + + +K L + K K K+ ++ P
Sbjct: 531 KPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPP 590
Query: 509 LAPTPAPQSTPRNTVSQSISGDPEIDKKIKNLKKKLKAIEQLKEQAATGKQ-LEKNQLEK 567
T P+ TP+ T + SG + + K K+K +E+ +T K+ L+ + + K
Sbjct: 591 SIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTK 650
Query: 568 IQKETALLQELEDL 581
+K + +++ED+
Sbjct: 651 AEKPARVSKDVEDV 664
Score = 33.9 bits (76), Expect = 0.43
Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 3/121 (2%)
Query: 449 PALRNKPITNSKLHEEEPPQN--MKPQSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKS 506
P LR K I K ++E P+ + +K K ++ + K E K K++ +
Sbjct: 136 PPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEK 195
Query: 507 PDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQLE 566
P+ T A + T +S + K K K K A + + Q K EK E
Sbjct: 196 PE-TKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKE 254
Query: 567 K 567
K
Sbjct: 255 K 255
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 38.1 bits (87), Expect = 0.023
Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 32/159 (20%)
Query: 451 LRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAAK---------QEA 501
LR T L P N+KP + SK +LK K K AK +EA
Sbjct: 289 LRYPVATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEA 348
Query: 502 RSDKSPDLAPT--------------PAPQSTPRNTVSQSISGDPE--IDKKI--KNLKKK 543
RS+ + +LA T PA + S+++ + I K+ K+LK+K
Sbjct: 349 RSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEK 408
Query: 544 LKAIEQLKEQ-----AATGKQLEKNQLEKIQKETALLQE 577
+ +E+ K++ K+L+K++ K +K+ A +E
Sbjct: 409 ISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEE 447
Score = 32.7 bits (73), Expect = 0.95
Identities = 43/184 (23%), Positives = 73/184 (39%), Gaps = 32/184 (17%)
Query: 430 AVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQR 489
A P V E + A + +++K K H +E ++ + +K K K +
Sbjct: 375 AKPERVKTESSEALKAEKRKLIKDKV---GKKHLKEKISKLEEKKDKEKKEIKKERKELK 431
Query: 490 KHEAKK-----AAKQEARSDKSPDLAPTPAPQSTP-----RNTV-------------SQS 526
K E +K A K+E R D P+L P P R T+ S++
Sbjct: 432 KDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRA 491
Query: 527 ISGDPEIDKKIKNLKKK-----LKAIEQLKEQA-ATGKQLEKNQLEKIQKETALLQELED 580
I G+ E+ + + + L I +E ++ + L ++ E ++E ALL E D
Sbjct: 492 IRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRD 551
Query: 581 LELG 584
LG
Sbjct: 552 TGLG 555
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 38.1 bits (87), Expect = 0.023
Identities = 31/160 (19%), Positives = 71/160 (44%), Gaps = 1/160 (0%)
Query: 424 KTITYQAVPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKT 483
K +T +++ + A A R + +K+ E + + ++ +++ ++
Sbjct: 880 KMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAE 939
Query: 484 ALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNLKKK 543
+RK E + + ++ D LA + N V +D+ I L K+
Sbjct: 940 LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 999
Query: 544 LKAIEQLKEQAATGKQLEKNQLEKIQK-ETALLQELEDLE 582
KA+++ +Q Q+E++++ + K +T L Q+++DLE
Sbjct: 1000 KKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLE 1039
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 37.7 bits (86), Expect = 0.030
Identities = 27/128 (21%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Query: 456 ITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAP 515
+ +K+ E + M + +++ ++ +RK E + + ++ D LA
Sbjct: 910 LIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 969
Query: 516 QSTPRNTVSQSISGDPEIDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQLEKIQK-ETAL 574
+ N V +D+ I L K+ KA+++ +QA Q+E++++ + K + L
Sbjct: 970 KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKL 1029
Query: 575 LQELEDLE 582
Q+++DLE
Sbjct: 1030 EQQVDDLE 1037
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 37.7 bits (86), Expect = 0.030
Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 305 KCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLISKPVASDS---T 361
KC + P +A +++ G ++V G+ G +WD + + + V D+ +
Sbjct: 158 KCLKTLSAHSDPVSAVHFNCSGSLIVS---GSYDGLCRIWDAASGQCLKTLVDDDNPPVS 214
Query: 362 YFAWCPDGEHILTATCAPRLRV---NNGYKIWHYTGSILHKYDVPSNAELWQVSW 413
+ + P+G++ILTAT L++ + G + YTG KY + +N + W
Sbjct: 215 FVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKW 269
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 37.0 bits (84), Expect = 0.050
Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 432 PSEVPNEEPKVATAYRPPALR-NKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRK 490
P +V + P+V PPA R KP S+ EE + +G +++ +K K
Sbjct: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG-----TRSQVKASEK 296
Query: 491 HEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEID-----KKIKNLKKKLK 545
+AA A+ +P TPAP SQ+ +G PE D ++ + +++
Sbjct: 297 ILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 546 AIEQLKEQAATGKQLEKNQLEKIQKET 572
A + L + A+GK + KE+
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKES 381
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 37.0 bits (84), Expect = 0.050
Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 432 PSEVPNEEPKVATAYRPPALR-NKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRK 490
P +V + P+V PPA R KP S+ EE + +G +++ +K K
Sbjct: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG-----TRSQVKASEK 296
Query: 491 HEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEID-----KKIKNLKKKLK 545
+AA A+ +P TPAP SQ+ +G PE D ++ + +++
Sbjct: 297 ILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 546 AIEQLKEQAATGKQLEKNQLEKIQKET 572
A + L + A+GK + KE+
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKES 381
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 37.0 bits (84), Expect = 0.050
Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 432 PSEVPNEEPKVATAYRPPALR-NKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRK 490
P +V + P+V PPA R KP S+ EE + +G +++ +K K
Sbjct: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG-----TRSQVKASEK 296
Query: 491 HEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEID-----KKIKNLKKKLK 545
+AA A+ +P TPAP SQ+ +G PE D ++ + +++
Sbjct: 297 ILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 546 AIEQLKEQAATGKQLEKNQLEKIQKET 572
A + L + A+GK + KE+
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKES 381
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 37.0 bits (84), Expect = 0.050
Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 432 PSEVPNEEPKVATAYRPPALR-NKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRK 490
P +V + P+V PPA R KP S+ EE + +G +++ +K K
Sbjct: 242 PGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG-----TRSQVKASEK 296
Query: 491 HEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEID-----KKIKNLKKKLK 545
+AA A+ +P TPAP SQ+ +G PE D ++ + +++
Sbjct: 297 ILQVRAASAPAKG--TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 546 AIEQLKEQAATGKQLEKNQLEKIQKET 572
A + L + A+GK + KE+
Sbjct: 355 AAKALLQAKASGKTSQVGAASAPAKES 381
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 37.0 bits (84), Expect = 0.050
Identities = 27/131 (20%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 456 ITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAP 515
+ SK+ E + + + +++ ++ +RK E + ++ D LA
Sbjct: 957 LIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKE 1016
Query: 516 QSTPRNTVSQSISGDPEIDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQLEKIQK-ETAL 574
+ N V +D+ + L K+ KA+++ +QA Q E++++ + K + L
Sbjct: 1017 KQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRL 1076
Query: 575 LQELEDLELGI 585
Q++EDLE +
Sbjct: 1077 EQQVEDLECSL 1087
Score = 35.0 bits (79), Expect = 0.19
Identities = 32/137 (23%), Positives = 64/137 (46%), Gaps = 8/137 (5%)
Query: 452 RNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKSPDLAP 511
R +T +KL E+ ++++ +K L + +RK E QE+ +D + D
Sbjct: 1065 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1124
Query: 512 TPAPQSTPRNTVSQ-SISGDPE------IDKKIKNLKKKLKAI-EQLKEQAATGKQLEKN 563
+ +SQ S+ + E + KKIK L+ + + + E+L+ + A ++EK
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1184
Query: 564 QLEKIQKETALLQELED 580
+ E ++ L + LE+
Sbjct: 1185 RAEAARELEELSERLEE 1201
>gi|50843827 activating molecule in beclin-1-regulated autophagy
[Homo sapiens]
Length = 1208
Score = 36.6 bits (83), Expect = 0.066
Identities = 20/56 (35%), Positives = 28/56 (50%)
Query: 77 KAVCLEFSPKNTVLATWQPYTTSKDGTAGIPNLQLYDVKTGTCLKSFIQKKMQNWC 132
K V L SP++T L + P T T N+ + +VKTG C+ S I + WC
Sbjct: 45 KRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWC 100
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 36.6 bits (83), Expect = 0.066
Identities = 36/179 (20%), Positives = 82/179 (45%), Gaps = 28/179 (15%)
Query: 431 VPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRK 490
+ + PN +P ++ P A + + T+ EPPQ+ + + + +S+ + +
Sbjct: 408 IANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE 467
Query: 491 HEAKKAAKQEARSDKSPD--------------------LAPTPAPQSTPRNTVSQS--IS 528
E + + + S P + PT AP+S ++ + ++ +
Sbjct: 468 DEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLR 527
Query: 529 GDPEID--KKIKNLKKKLKAIEQLKEQAA---TGKQLEKNQLEKIQKETALLQELEDLE 582
DP+ ++++NL++K +A EQL+ Q ++LE+ +L++ ++ +LQ E +E
Sbjct: 528 MDPKEKERQRLENLRRKEEA-EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE 585
>gi|42558250 membrane component chromosome 11 surface marker 1
isoform 1 [Homo sapiens]
Length = 709
Score = 36.6 bits (83), Expect = 0.066
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 533 IDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELE 579
IDKK++NL+KK ++ +E+ G++L ++QL+ + K + LE
Sbjct: 61 IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLE 107
>gi|42734503 membrane component chromosome 11 surface marker 1
isoform 2 [Homo sapiens]
Length = 694
Score = 36.6 bits (83), Expect = 0.066
Identities = 16/47 (34%), Positives = 30/47 (63%)
Query: 533 IDKKIKNLKKKLKAIEQLKEQAATGKQLEKNQLEKIQKETALLQELE 579
IDKK++NL+KK ++ +E+ G++L ++QL+ + K + LE
Sbjct: 61 IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLE 107
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 36.2 bits (82), Expect = 0.086
Identities = 36/183 (19%), Positives = 82/183 (44%), Gaps = 32/183 (17%)
Query: 431 VPSEVPNEEPKVATAYRPPALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRK 490
+ + PN +P ++ P A + + T+ EPPQ+ + + + +S+ + +
Sbjct: 408 IANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLE 467
Query: 491 HEAKKAAKQEARSDKSPD--------------------LAPTPAPQSTPRNTVSQS--IS 528
E + + + S P + PT AP+S ++ + ++ +
Sbjct: 468 DEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLR 527
Query: 529 GDPEID------KKIKNLKKKLKAIEQLKEQAA---TGKQLEKNQLEKIQKETALLQELE 579
DP+ ++++NL++K +A EQL+ Q ++LE+ +L++ ++ +LQ E
Sbjct: 528 MDPKCSFVEKERQRLENLRRKEEA-EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARE 586
Query: 580 DLE 582
+E
Sbjct: 587 RVE 589
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,064,189
Number of Sequences: 37866
Number of extensions: 1231356
Number of successful extensions: 5186
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 4813
Number of HSP's gapped (non-prelim): 576
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.