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Search of human proteins with 54792787
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54792787 complement factor H-related 3 [Homo sapiens]
(330 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54792787 complement factor H-related 3 [Homo sapiens] 719 0.0
gi|117320518 complement factor H-related 4 [Homo sapiens] 475 e-134
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 373 e-103
gi|118442839 complement factor H-related 1 [Homo sapiens] 304 6e-83
gi|239758113 PREDICTED: similar to complement factor H-related 1... 304 6e-83
gi|62739188 complement factor H isoform b precursor [Homo sapiens] 269 2e-72
gi|5031695 H factor (complement)-like 3 [Homo sapiens] 225 4e-59
gi|239758115 PREDICTED: similar to complement factor H-related 1... 211 6e-55
gi|13540563 complement factor H-related 5 [Homo sapiens] 198 6e-51
gi|110611237 coagulation factor XIII B subunit precursor [Homo s... 162 5e-40
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 84 2e-16
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 84 2e-16
gi|148886654 polydom [Homo sapiens] 82 9e-16
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 79 6e-15
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 79 6e-15
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 79 6e-15
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 78 1e-14
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 71 1e-12
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 71 1e-12
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 71 2e-12
gi|148539593 sushi domain containing 4 isoform a [Homo sapiens] 69 6e-12
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 62 7e-10
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 62 7e-10
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 62 7e-10
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 62 7e-10
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 61 1e-09
gi|4502503 complement component 4 binding protein, alpha chain p... 59 8e-09
gi|153266841 apolipoprotein H precursor [Homo sapiens] 54 1e-07
gi|62912468 complement component 4 binding protein, beta chain i... 53 4e-07
gi|62912464 complement component 4 binding protein, beta chain i... 53 4e-07
>gi|54792787 complement factor H-related 3 [Homo sapiens]
Length = 330
Score = 719 bits (1856), Expect = 0.0
Identities = 330/330 (100%), Positives = 330/330 (100%)
Query: 1 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE 60
MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE
Sbjct: 1 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE 60
Query: 61 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL 120
TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL
Sbjct: 61 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL 120
Query: 121 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA 180
PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA
Sbjct: 121 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA 180
Query: 181 TADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ 240
TADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ
Sbjct: 181 TADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ 240
Query: 241 PYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEF 300
PYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEF
Sbjct: 241 PYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEF 300
Query: 301 MCKLGYNANTSILSFQAVCREGIVEYPRCE 330
MCKLGYNANTSILSFQAVCREGIVEYPRCE
Sbjct: 301 MCKLGYNANTSILSFQAVCREGIVEYPRCE 330
>gi|117320518 complement factor H-related 4 [Homo sapiens]
Length = 331
Score = 475 bits (1223), Expect = e-134
Identities = 224/336 (66%), Positives = 260/336 (77%), Gaps = 11/336 (3%)
Query: 1 MLLLINVILTLWVSCANGQ-VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHF 59
MLLLINVILTLWVSCANGQ VKPCDFP+I+HGGL+++++RR YFP A G+ YSYYCD++F
Sbjct: 1 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF 60
Query: 60 ETPSGSYWDYIHCTQNGWSPAVPCLRKCYFP--YLENGYNQNYGRKFVQGNSTEVACHPG 117
TPSGSYWDYIHCTQ+GWSP VPCLR C +ENG+ ++ + C PG
Sbjct: 61 VTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPG 120
Query: 118 YGLPKAQTT--VTCTEKGWSPTPRCIRVRTCSKSDIEI-ENGFISESSSIYILNKEIQYK 174
Y ++ +TC + GWS P CI+ D+ + EN + + L+ + Y+
Sbjct: 121 YATADGNSSGSITCLQNGWSAQPICIKF-----CDMPVFENSRAKSNGMRFKLHDTLDYE 175
Query: 175 CKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSR 234
C GY + GN++GSI C ++GWS P C NSSEKCGPPPPISNGDTTSFLLKVYVPQSR
Sbjct: 176 CYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSR 235
Query: 235 VEYQCQPYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKT 294
VEYQCQ YYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNI+LKG+SD KYYAKT
Sbjct: 236 VEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKT 295
Query: 295 GDTIEFMCKLGYNANTSILSFQAVCREGIVEYPRCE 330
GDTIEFMCKLGYNANTS+LSFQAVCREGIVEYPRCE
Sbjct: 296 GDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE 331
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 373 bits (957), Expect = e-103
Identities = 178/300 (59%), Positives = 211/300 (70%), Gaps = 13/300 (4%)
Query: 10 TLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDY 69
T W+ +KPCD+PDIKHGGL+HENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWD+
Sbjct: 312 TGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDH 371
Query: 70 IHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTC 129
IHCTQ+GWSPAVPCLRKCYFPYLENGYNQN+GRKFVQG S +VACHPGY LPKAQTTVTC
Sbjct: 372 IHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTC 431
Query: 130 TEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGS 189
E GWSPTPRCIRV+TCSKS I+IENGFISES Y L ++ +Y+CK GY TADG +SGS
Sbjct: 432 MENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGS 491
Query: 190 ITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYEL---Q 246
ITC ++GWSAQP CI S + + D T F L ++Y+C YE
Sbjct: 492 ITCGKDGWSAQPTCIKSCDIPVFMNARTKNDFTWFKL-----NDTLDYECHDGYESNTGS 546
Query: 247 GSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
+ + C WS+ P C E + K ++ L + Y K G+ ++F CK G+
Sbjct: 547 TTGSIVCGYNGWSDLPICYE----RECELPKIDVHLVPDRKKDQY-KVGEVLKFSCKPGF 601
Score = 197 bits (500), Expect = 1e-50
Identities = 111/323 (34%), Positives = 162/323 (50%), Gaps = 19/323 (5%)
Query: 12 WVSCANGQVKPCDFP-DIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYI 70
W S + PC P +I HG + H + Y G+ +Y C E F +
Sbjct: 920 WSSPPQCEGLPCKSPPEISHGVVAHMSDSYQY-----GEEVTYKCFEGFGIDGPAI---A 971
Query: 71 HCTQNGWSPAVPCLRK--CYFPYLENGYNQNYGRK-FVQGNSTEVACHPGYGLPKAQTTV 127
C WS C++ P EN + + G C Y + A + V
Sbjct: 972 KCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGA-SNV 1030
Query: 128 TCTEKGWSPTPRCIRVRTCSKSDIEIENGFI-SESSSIYILNKEIQYKCKPGYATADGNS 186
TC W+ P C R +C ++N +I S S Y + ++Y+C+ Y
Sbjct: 1031 TCINSRWTGRPTC-RDTSCVNPPT-VQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEE 1088
Query: 187 SGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQ 246
+ CL W+ P C +S+ KCGPPPPI NGD TSF L VY P S VEYQCQ Y+L+
Sbjct: 1089 ---VMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLE 1145
Query: 247 GSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
G+ +TC NG+WSEPP+C+HPC+I+ E M NI L+ + +K Y++TG+++EF+CK GY
Sbjct: 1146 GNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGY 1205
Query: 307 NANTSILSFQAVCREGIVEYPRC 329
++ + + C +G +EYP C
Sbjct: 1206 RLSSRSHTLRTTCWDGKLEYPTC 1228
Score = 119 bits (298), Expect = 4e-27
Identities = 89/320 (27%), Positives = 133/320 (41%), Gaps = 28/320 (8%)
Query: 19 QVKPCDFPDIK-HGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGW 77
+VK C I G E+ + A+ + Y C + T G I C ++GW
Sbjct: 444 RVKTCSKSSIDIENGFISESQ----YTYALKEKAKYQCKLGYVTADGETSGSITCGKDGW 499
Query: 78 SPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTT--VTCTEKGWS 135
S C++ C P N +N F ++ + CH GY TT + C GWS
Sbjct: 500 SAQPTCIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWS 559
Query: 136 PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN 195
P C R C I++ Y + + +++ CKPG+ NS + C
Sbjct: 560 DLPICYE-RECELPKIDVHL-VPDRKKDQYKVGEVLKFSCKPGFTIVGPNS---VQCYHF 614
Query: 196 GWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS 254
G S PIC + CGPPP + NG+ + Y VEY C P + ++G N + C
Sbjct: 615 GLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV 674
Query: 255 NGEWSEPPRCIHPCIITEENMNKNNIKLK----GRSDRKYYAKTGDTIEFMCKLGYNANT 310
+GEW+ P C I EE+ + +L+ S YY GD++EF C + T
Sbjct: 675 DGEWTTLPVC-----IVEESTCGDIPELEHGWAQLSSPPYY--YGDSVEFNCSESF---T 724
Query: 311 SILSFQAVCREGI-VEYPRC 329
I C G+ + P+C
Sbjct: 725 MIGHRSITCIHGVWTQLPQC 744
Score = 99.4 bits (246), Expect = 4e-21
Identities = 85/319 (26%), Positives = 126/319 (39%), Gaps = 35/319 (10%)
Query: 23 CDFPDIKHGG------LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG 76
C PD+ +G ++ EN R + Y C+ +E D + CT++G
Sbjct: 210 CKSPDVINGSPISQKIIYKENER-----------FQYKCNMGYEYSERG--DAV-CTESG 255
Query: 77 WSPAVPCLRK-CYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWS 135
W P C K C PY+ NG K G+ C G+ T CT GW
Sbjct: 256 WRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI 315
Query: 136 PTPRCIRVRTCSKSDIEIENGFISESSSIYI---LNKEIQYKCKPGYATADGNSSGSITC 192
P PRC ++ C DI+ + Y + K Y C + T G+ I C
Sbjct: 316 PAPRC-TLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHC 374
Query: 193 LQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYEL-QGSNYV 251
Q+GWS C+ KC P + NG + K +V ++ C P Y L + V
Sbjct: 375 TQDGWSPAVPCL---RKC-YFPYLENGYNQNHGRK-FVQGKSIDVACHPGYALPKAQTTV 429
Query: 252 TCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTS 311
TC WS PRCI ++ +++ N + S+ +Y + ++ CKLGY
Sbjct: 430 TCMENGWSPTPRCIRVKTCSKSSIDIENGFI---SESQYTYALKEKAKYQCKLGYVTADG 486
Query: 312 ILSFQAVC-REGIVEYPRC 329
S C ++G P C
Sbjct: 487 ETSGSITCGKDGWSAQPTC 505
Score = 82.4 bits (202), Expect = 5e-16
Identities = 68/298 (22%), Positives = 117/298 (39%), Gaps = 28/298 (9%)
Query: 19 QVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWS 78
QV+ C P G E + Y + YYC+ F + I C W+
Sbjct: 626 QVQSCGPPPELLNGNVKEKTKEEY---GHSEVVEYYCNPRFLMKGPNK---IQCVDGEWT 679
Query: 79 PAVPCLRK---CY-FPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGW 134
C+ + C P LE+G+ Q + G+S E C + + ++TC W
Sbjct: 680 TLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMI-GHRSITCIHGVW 738
Query: 135 SPTPRCI---RVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSI- 190
+ P+C+ +++ C S++ I + + N I+Y+C+ G I
Sbjct: 739 TQLPQCVAIDKLKKCKSSNLIILEEHLKNKKE-FDHNSNIRYRCR--------GKEGWIH 789
Query: 191 -TCLQNGWSAQPICINSS-EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGS 248
C+ W + C + + C PPP I N + L Y +V CQ Y +Q
Sbjct: 790 TVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLN-YRDGEKVSVLCQENYLIQEG 848
Query: 249 NYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
+TC +G W P C+ ++ ++ RS ++ YA G + + C+ G+
Sbjct: 849 EEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAH-GTKLSYTCEGGF 905
Score = 65.1 bits (157), Expect = 8e-11
Identities = 59/251 (23%), Positives = 98/251 (39%), Gaps = 27/251 (10%)
Query: 24 DFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIH--CTQNGWSPAV 81
D P+++HG + + PY+ G + C E F IH TQ A+
Sbjct: 693 DIPELEHG--WAQLSSPPYY---YGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAI 747
Query: 82 PCLRKCYFPYL----ENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPT 137
L+KC L E+ N+ ++F ++ C G C W P
Sbjct: 748 DKLKKCKSSNLIILEEHLKNK---KEFDHNSNIRYRCRGKEGW----IHTVCINGRWDPE 800
Query: 138 PRC--IRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN 195
C +++ C +I N ++ Y +++ C+ Y +G ITC
Sbjct: 801 VNCSMAQIQLCPPPP-QIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE---ITCKDG 856
Query: 196 GWSAQPICINSSEKCGPPPPISNGDTTSFLL--KVYVPQSRVEYQCQPYYELQGSNYVTC 253
W + P+C+ C PP I +G S + Y +++ Y C+ + + N TC
Sbjct: 857 RWQSIPLCVEKIP-CSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTC 915
Query: 254 SNGEWSEPPRC 264
G+WS PP+C
Sbjct: 916 YMGKWSSPPQC 926
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 17/156 (10%)
Query: 159 SESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISN 218
S S Y + YKC+PGY + GN + C + W + +N KC P
Sbjct: 36 SWSDQTYPEGTQAIYKCRPGYRSL-GNV--IMVCRKGEW----VALNPLRKCQKRPCGHP 88
Query: 219 GDTT--SFLL---KVYVPQSRVEYQCQPYYELQGS-NYVTCSNGEW-SEPPRC-IHPCII 270
GDT +F L V+ + Y C Y+L G NY C W ++ P C + C+
Sbjct: 89 GDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLP 148
Query: 271 TEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
N + DR+Y+ G + F+C GY
Sbjct: 149 VTAPENGKIVSSAMEPDREYH--FGQAVRFVCNSGY 182
Score = 35.0 bits (79), Expect = 0.092
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 202 ICINSSEKCGPPPPISNGD--TTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEW 258
IC+ +E C PP N + T S+ + Y ++ Y+C+P Y G+ + C GEW
Sbjct: 15 ICV--AEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEW 71
>gi|118442839 complement factor H-related 1 [Homo sapiens]
Length = 330
Score = 304 bits (779), Expect = 6e-83
Identities = 134/330 (40%), Positives = 202/330 (61%), Gaps = 4/330 (1%)
Query: 1 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE 60
M LL++VIL +S G+ CDFP I HG L+ E +P+ V G+ + Y C+ +F
Sbjct: 1 MWLLVSVILISRISSVGGEATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFV 60
Query: 61 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL 120
+PS S+W I CT+ GWSP CLR C+FP++ENG++++ G+ ++G++ ++ C+ GY L
Sbjct: 61 SPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRL 120
Query: 121 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFI-SESSSIYILNKEIQYKCKPGY 179
+ ++C E+GWS P+C T + ++N I S S Y + ++Y+C+ Y
Sbjct: 121 QNNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYECRSPY 180
Query: 180 ATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC 239
+ CL W+ P C +S+ KCGPPPPI NGD TSF L VY P S VEYQC
Sbjct: 181 EMFGDEE---VMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQC 237
Query: 240 QPYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIE 299
Q Y+L+G+ +TC NG+WSEPP+C+HPC+I+ E M NI L+ + +K Y +TG++ E
Sbjct: 238 QNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAE 297
Query: 300 FMCKLGYNANTSILSFQAVCREGIVEYPRC 329
F+CK GY ++ + + C +G +EYP C
Sbjct: 298 FVCKRGYRLSSRSHTLRTTCWDGKLEYPTC 327
>gi|239758113 PREDICTED: similar to complement factor H-related 1
isoform 1 [Homo sapiens]
Length = 330
Score = 304 bits (779), Expect = 6e-83
Identities = 134/330 (40%), Positives = 202/330 (61%), Gaps = 4/330 (1%)
Query: 1 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE 60
M LL++VIL +S G+ CDFP I HG L+ E +P+ V G+ + Y C+ +F
Sbjct: 1 MWLLVSVILISRISSVGGEATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFV 60
Query: 61 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL 120
+PS S+W I CT+ GWSP CLR C+FP++ENG++++ G+ ++G++ ++ C+ GY L
Sbjct: 61 SPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRL 120
Query: 121 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFI-SESSSIYILNKEIQYKCKPGY 179
+ ++C E+GWS P+C T + ++N I S S Y + ++Y+C+ Y
Sbjct: 121 QNNENNISCVERGWSTPPKCRSTDTSCVNPPTVQNAHILSRQMSKYPSGERVRYECRSPY 180
Query: 180 ATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC 239
+ CL W+ P C +S+ KCGPPPPI NGD TSF L VY P S VEYQC
Sbjct: 181 EMFGDEE---VMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQC 237
Query: 240 QPYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIE 299
Q Y+L+G+ +TC NG+WSEPP+C+HPC+I+ E M NI L+ + +K Y +TG++ E
Sbjct: 238 QNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAE 297
Query: 300 FMCKLGYNANTSILSFQAVCREGIVEYPRC 329
F+CK GY ++ + + C +G +EYP C
Sbjct: 298 FVCKRGYRLSSRSHTLRTTCWDGKLEYPTC 327
>gi|62739188 complement factor H isoform b precursor [Homo sapiens]
Length = 449
Score = 269 bits (688), Expect = 2e-72
Identities = 114/134 (85%), Positives = 122/134 (91%)
Query: 10 TLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDY 69
T W+ +KPCD+PDIKHGGL+HENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWD+
Sbjct: 312 TGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDH 371
Query: 70 IHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTC 129
IHCTQ+GWSPAVPCLRKCYFPYLENGYNQN+GRKFVQG S +VACHPGY LPKAQTTVTC
Sbjct: 372 IHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTC 431
Query: 130 TEKGWSPTPRCIRV 143
E GWSPTPRCIRV
Sbjct: 432 MENGWSPTPRCIRV 445
Score = 89.0 bits (219), Expect = 5e-18
Identities = 72/254 (28%), Positives = 100/254 (39%), Gaps = 31/254 (12%)
Query: 23 CDFPDIKHGG------LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG 76
C PD+ +G ++ EN R + Y C+ +E D + CT++G
Sbjct: 210 CKSPDVINGSPISQKIIYKENER-----------FQYKCNMGYEYSERG--DAV-CTESG 255
Query: 77 WSPAVPCLRK-CYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWS 135
W P C K C PY+ NG K G+ C G+ T CT GW
Sbjct: 256 WRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWI 315
Query: 136 PTPRCIRVRTCSKSDIEIENGFISESSSIYI---LNKEIQYKCKPGYATADGNSSGSITC 192
P PRC ++ C DI+ + Y + K Y C + T G+ I C
Sbjct: 316 PAPRC-TLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHC 374
Query: 193 LQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYEL-QGSNYV 251
Q+GWS C+ KC P + NG + K +V ++ C P Y L + V
Sbjct: 375 TQDGWSPAVPCL---RKC-YFPYLENGYNQNHGRK-FVQGKSIDVACHPGYALPKAQTTV 429
Query: 252 TCSNGEWSEPPRCI 265
TC WS PRCI
Sbjct: 430 TCMENGWSPTPRCI 443
Score = 80.1 bits (196), Expect = 3e-15
Identities = 59/208 (28%), Positives = 88/208 (42%), Gaps = 29/208 (13%)
Query: 12 WVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAV----GKYYSYYCDEHFETPSGSYW 67
W + + K CD P I +G Y P+ + G +Y C F +
Sbjct: 256 WRPLPSCEEKSCDNPYIPNGD---------YSPLRIKHRTGDEITYQCRNGFYPATRG-- 304
Query: 68 DYIHCTQNGWSPAVPC-LRKCYFPYLENG--YNQNYGRKFVQ---GNSTEVACHPGYGLP 121
+ CT GW PA C L+ C +P +++G Y++N R + G C + P
Sbjct: 305 NTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETP 364
Query: 122 KAQ--TTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGY 179
+ CT+ GWSP C+R C +ENG+ ++ K I C PGY
Sbjct: 365 SGSYWDHIHCTQDGWSPAVPCLR--KCYFP--YLENGYNQNHGRKFVQGKSIDVACHPGY 420
Query: 180 ATADGNSSGSITCLQNGWSAQPICINSS 207
A ++ +TC++NGWS P CI S
Sbjct: 421 ALPKAQTT--VTCMENGWSPTPRCIRVS 446
Score = 54.7 bits (130), Expect = 1e-07
Identities = 59/236 (25%), Positives = 85/236 (36%), Gaps = 23/236 (9%)
Query: 101 GRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISE 160
G F G C+ GY L C GW+ V C ENG I
Sbjct: 101 GNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAP-ENGKIVS 159
Query: 161 SSSI----YILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQ-PICINSSEKCGPPP 214
S+ Y + +++ C GY + C +G WS + P C+ S K P
Sbjct: 160 SAMEPDREYHFGQAVRFVCNSGYKI---EGDEEMHCSDDGFWSKEKPKCVEISCKS---P 213
Query: 215 PISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSEPPRCIHPCIITEEN 274
+ NG S + +Y R +Y+C YE C+ W P C E++
Sbjct: 214 DVINGSPISQKI-IYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSC------EEKS 266
Query: 275 MNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQAVCRE-GIVEYPRC 329
+ I S + +TGD I + C+ G+ T A C G + PRC
Sbjct: 267 CDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATR--GNTAKCTSTGWIPAPRC 320
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 17/156 (10%)
Query: 159 SESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISN 218
S S Y + YKC+PGY + GN + C + W + +N KC P
Sbjct: 36 SWSDQTYPEGTQAIYKCRPGYRSL-GNV--IMVCRKGEW----VALNPLRKCQKRPCGHP 88
Query: 219 GDTT--SFLL---KVYVPQSRVEYQCQPYYELQGS-NYVTCSNGEW-SEPPRC-IHPCII 270
GDT +F L V+ + Y C Y+L G NY C W ++ P C + C+
Sbjct: 89 GDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLP 148
Query: 271 TEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
N + DR+Y+ G + F+C GY
Sbjct: 149 VTAPENGKIVSSAMEPDREYH--FGQAVRFVCNSGY 182
Score = 35.0 bits (79), Expect = 0.092
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 202 ICINSSEKCGPPPPISNGD--TTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEW 258
IC+ +E C PP N + T S+ + Y ++ Y+C+P Y G+ + C GEW
Sbjct: 15 ICV--AEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEW 71
>gi|5031695 H factor (complement)-like 3 [Homo sapiens]
Length = 270
Score = 225 bits (574), Expect = 4e-59
Identities = 113/253 (44%), Positives = 158/253 (62%), Gaps = 16/253 (6%)
Query: 87 CYFPYLENG--YNQNYGRKFVQGNSTEV---ACHPGYGLPKAQ--TTVTCTEKGWSPTPR 139
C FP + +G Y++ + F Q + EV +C + P T +TC E+GWSPTP+
Sbjct: 23 CDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPK 82
Query: 140 CIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSA 199
C+R+ +ENG S ++ +Q C GY N+ +I+C++ GWS
Sbjct: 83 CLRLCFFPF----VENGHSESSGQTHLEGDTVQIICNTGYRLQ--NNENNISCVERGWST 136
Query: 200 QPICIN--SSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGE 257
P C + S+EKCGPPPPI NGD TSFLL VY P S VEYQCQ Y+L+G+N +TC NG+
Sbjct: 137 PPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQ 196
Query: 258 WSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQA 317
WSEPP+C+ PC+I++E M K NIKLK + +K Y++TGD +EF+CK GY+ T SF+A
Sbjct: 197 WSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHP-TKSHSFRA 255
Query: 318 VCREGIVEYPRCE 330
+C+ G + YP CE
Sbjct: 256 MCQNGKLVYPSCE 268
Score = 157 bits (396), Expect = 2e-38
Identities = 75/209 (35%), Positives = 117/209 (55%), Gaps = 8/209 (3%)
Query: 1 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE 60
M LL++VIL +S G+ CDFP I HG L+ E +P+ V G+ + Y C+ +F
Sbjct: 1 MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFV 60
Query: 61 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL 120
+PS S+W I C + GWSP CLR C+FP++ENG++++ G+ ++G++ ++ C+ GY L
Sbjct: 61 SPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRL 120
Query: 121 PKAQTTVTCTEKGWSPTPRC---IRVRTCSKSDIEIENGFI-SESSSIYILNKEIQYKCK 176
+ ++C E+GWS P+C I C I+NG I S S+Y ++Y+C+
Sbjct: 121 QNNENNISCVERGWSTPPKCRSTISAEKCGPPP-PIDNGDITSFLLSVYAPGSSVEYQCQ 179
Query: 177 PGYATADGNSSGSITCLQNGWSAQPICIN 205
Y N ITC WS P C++
Sbjct: 180 NLYQLEGNN---QITCRNGQWSEPPKCLD 205
>gi|239758115 PREDICTED: similar to complement factor H-related 1
isoform 2 [Homo sapiens]
Length = 271
Score = 211 bits (538), Expect = 6e-55
Identities = 104/252 (41%), Positives = 150/252 (59%), Gaps = 15/252 (5%)
Query: 87 CYFPYLENG--YNQNYGRKFVQGNSTEV---ACHPGYGLPKAQ--TTVTCTEKGWSPTPR 139
C FP + +G Y++ + F Q + EV +C + P T +TCTE+GWSPTP+
Sbjct: 23 CDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSPTPK 82
Query: 140 CIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSA 199
C+R+ +ENG S ++ +Q C GY N+ +I+C++ GWS
Sbjct: 83 CLRLCFFPF----VENGHSESSGQTHLEGDTVQIICNTGYRLQ--NNENNISCVERGWST 136
Query: 200 QPIC--INSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGE 257
P C +S+ KCGPPPPI NGD TSF L VY P S VEYQCQ Y+L+G+ +TC NG+
Sbjct: 137 PPKCRSTDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQ 196
Query: 258 WSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQA 317
WSEPP+C+HPC+I+ E M NI L+ + +K Y +TG++ EF+CK GY ++ + +
Sbjct: 197 WSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRT 256
Query: 318 VCREGIVEYPRC 329
C +G +EYP C
Sbjct: 257 TCWDGKLEYPTC 268
Score = 157 bits (397), Expect = 1e-38
Identities = 76/208 (36%), Positives = 120/208 (57%), Gaps = 6/208 (2%)
Query: 1 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE 60
M LL++VIL +S G+ CDFP I HG L+ E +P+ V G+ + Y C+ +F
Sbjct: 1 MWLLVSVILISRISSVGGEATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFV 60
Query: 61 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL 120
+PS S+W I CT+ GWSP CLR C+FP++ENG++++ G+ ++G++ ++ C+ GY L
Sbjct: 61 SPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRL 120
Query: 121 PKAQTTVTCTEKGWSPTPRCIRVRTCSK--SDIEIENGFI-SESSSIYILNKEIQYKCKP 177
+ ++C E+GWS P+C + K I+NG I S S+Y ++Y+C+
Sbjct: 121 QNNENNISCVERGWSTPPKCRSTDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQN 180
Query: 178 GYATADGNSSGSITCLQNGWSAQPICIN 205
Y +GN ITC WS P C++
Sbjct: 181 LY-QLEGNK--RITCRNGQWSEPPKCLH 205
>gi|13540563 complement factor H-related 5 [Homo sapiens]
Length = 569
Score = 198 bits (503), Expect = 6e-51
Identities = 126/377 (33%), Positives = 167/377 (44%), Gaps = 74/377 (19%)
Query: 18 GQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGW 77
GQV+ C P G E + Y + Y C+ +F I C W
Sbjct: 203 GQVRSCGPPPQLSNGEVKEIRKEEY---GHNEVVEYDCNPNFIINGPKK---IQCVDGEW 256
Query: 78 SPAVPCLRKC----YFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG 133
+ C+ + Y P LE GY Q + G S EV C Y + +TC
Sbjct: 257 TTLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMI-GNNMITCINGI 315
Query: 134 WSPTPRC-------------IRVRTCSK----------------SDI------------- 151
W+ P C + ++T K SDI
Sbjct: 316 WTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHSVCINGKW 375
Query: 152 ------------------EIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL 193
+I N ++ Y +++ CK Y + I C
Sbjct: 376 NPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKE---IVCK 432
Query: 194 QNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC 253
W + P C+ S+ CGPPP I+NGDTTSF L VY P S V Y+CQ +Y+LQGS VTC
Sbjct: 433 DGRWQSLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTC 492
Query: 254 SNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSIL 313
N +WSEPPRC+ PC+++EENMNKNNI+LK R+D K YAKTGD +EF CK + A S
Sbjct: 493 RNKQWSEPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSP 552
Query: 314 SFQAVCREGIVEYPRCE 330
F+A+C+EG EYP CE
Sbjct: 553 PFRAICQEGKFEYPICE 569
Score = 194 bits (493), Expect = 9e-50
Identities = 92/266 (34%), Positives = 137/266 (51%), Gaps = 4/266 (1%)
Query: 1 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE 60
MLLL +VIL WVS G+ CDFP I HG L+ E P+ V G+ + Y C+ +F
Sbjct: 1 MLLLFSVILISWVSTVGGEGTLCDFPKIHHGFLYDEEDYNPFSQVPTGEVFYYSCEYNFV 60
Query: 61 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL 120
+PS S+W I CT+ GWSP CLR C FP+++NG++++ G ++G++ ++ C+ GY L
Sbjct: 61 SPSKSFWTRITCTEEGWSPTPKCLRMCSFPFVKNGHSESSGLIHLEGDTVQIICNTGYSL 120
Query: 121 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA 180
+ ++C E+GWS P C + I N Y + +++ C+
Sbjct: 121 QNNEKNISCVERGWSTPPICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLI 180
Query: 181 TADGNSSGSITCLQNGWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC 239
S S+ C Q GWS P C CGPPP +SNG+ + Y VEY C
Sbjct: 181 RV---GSDSVQCYQFGWSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDC 237
Query: 240 QPYYELQGSNYVTCSNGEWSEPPRCI 265
P + + G + C +GEW+ P C+
Sbjct: 238 NPNFIINGPKKIQCVDGEWTTLPTCV 263
Score = 30.8 bits (68), Expect = 1.7
Identities = 21/88 (23%), Positives = 36/88 (40%), Gaps = 12/88 (13%)
Query: 237 YQCQPYYELQGSNY---VTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRK-YYA 292
Y C+ + ++ +TC+ WS P+C+ C KN G S+
Sbjct: 53 YSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRMCSFP---FVKN-----GHSESSGLIH 104
Query: 293 KTGDTIEFMCKLGYNANTSILSFQAVCR 320
GDT++ +C GY+ + + V R
Sbjct: 105 LEGDTVQIICNTGYSLQNNEKNISCVER 132
>gi|110611237 coagulation factor XIII B subunit precursor [Homo
sapiens]
Length = 661
Score = 162 bits (409), Expect = 5e-40
Identities = 93/291 (31%), Positives = 138/291 (47%), Gaps = 18/291 (6%)
Query: 48 GKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLR----KCYFPYLE-NGYNQNYGR 102
G ++C E++ SGS D I C GW P P +C P L N Q +
Sbjct: 234 GDVVQFFCHENYYL-SGS--DLIQCYNFGWYPESPVCEGRRNRCPPPPLPINSKIQTHST 290
Query: 103 KFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCI--RVRTCSKSDIEIENGFISE 160
+ G + C + + + C + W+ P+CI + + + IENG +
Sbjct: 291 TYRHGEIVHIECELNFEI-HGSAEIRCEDGKWTEPPKCIEGQEKVACEEPPFIENGAANL 349
Query: 161 SSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGD 220
S IY ++ Y CK GY + S ITC + W+ P C+ ++E C PP + NG
Sbjct: 350 HSKIYYNGDKVTYACKSGYLL---HGSNEITCNRGKWTLPPECVENNENCKHPPVVMNGA 406
Query: 221 TTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNI 280
+L Y S VEY+C YY L+GS C G+WS PP C+ PC + + MN+NNI
Sbjct: 407 VADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSPPVCLEPCTVNVDYMNRNNI 466
Query: 281 KLKGRSDRKYYAKTGDTIEFMCKLGYNAN--TSILSFQAVCREGIVEYPRC 329
++K + + K GD I+F+CK GY+ + T + C G V+YP C
Sbjct: 467 EMKWKYEGK--VLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLC 515
Score = 130 bits (327), Expect = 2e-30
Identities = 79/250 (31%), Positives = 115/250 (46%), Gaps = 11/250 (4%)
Query: 21 KPCDFPDIKHGGL--FHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWS 78
KPC FP +++G + ++ + YFP+++ K S++C + T SG + CT GWS
Sbjct: 23 KPCGFPHVENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEGWS 82
Query: 79 PAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLP--KAQTTVTCTEKGWSP 136
P C +KC P L NGY + + + C GY K + V C GWS
Sbjct: 83 PEPRCFKKCTKPDLSNGYISDVKLLYKIQENMRYGCASGYKTTGGKDEEVVQCLSDGWSS 142
Query: 137 TPRCIRV-RTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN 195
P C + TC E+ NG S + + + ++QY+C GY TA G + + CL
Sbjct: 143 QPTCRKEHETCLAP--ELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTY 200
Query: 196 GWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSN 255
GWS P C + KC I NG + + Y V++ C Y L GS+ + C N
Sbjct: 201 GWSLTPKC--TKLKCSSLRLIENGYFHP-VKQTYEEGDVVQFFCHENYYLSGSDLIQCYN 257
Query: 256 GEW-SEPPRC 264
W E P C
Sbjct: 258 FGWYPESPVC 267
Score = 103 bits (256), Expect = 3e-22
Identities = 90/331 (27%), Positives = 136/331 (41%), Gaps = 27/331 (8%)
Query: 15 CANGQVK-PCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCT 73
C GQ K C+ P G + + + Y G +Y C + + I C
Sbjct: 327 CIEGQEKVACEEPPFIENGAANLHSKIYYN----GDKVTYACKSGYLLHGSNE---ITCN 379
Query: 74 QNGWSPAVPCLRK---CYFP--YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVT 128
+ W+ C+ C P + + G+S E C+ Y L +
Sbjct: 380 RGKWTLPPECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYY-LLRGSKISR 438
Query: 129 CTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKE-IQYKCKPGYATADGN-- 185
C + WS P C+ T + + N + +L+ + I + CK GY +
Sbjct: 439 CEQGKWSSPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPL 498
Query: 186 SSGSITCLQNGWSAQPICINSSEK--CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYY 243
S S+ C G P+C K C PP I +G S + Y S VEY+C ++
Sbjct: 499 SELSVQC-NRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHH 557
Query: 244 ELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCK 303
L+GS C +G W+ PP C+ PC ++ M KNN+ LK D + + G+ IEF+C+
Sbjct: 558 FLEGSREAYCLDGMWTTPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFICR 617
Query: 304 LG-YNANT----SILSFQAVCREGIVEYPRC 329
Y A SIL Q C G ++YPRC
Sbjct: 618 GDTYPAELYITGSILRMQ--CDRGQLKYPRC 646
Score = 31.6 bits (70), Expect = 1.0
Identities = 25/102 (24%), Positives = 39/102 (38%), Gaps = 16/102 (15%)
Query: 214 PPISNGDTTSFLL---KVYVPQS---RVEYQCQPYYELQGSNY---VTCSNGEWSEPPRC 264
P + NG + Y P S ++ + C Y + TC+ WS PRC
Sbjct: 28 PHVENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEGWSPEPRC 87
Query: 265 IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
C T+ +++ I SD K K + + + C GY
Sbjct: 88 FKKC--TKPDLSNGYI-----SDVKLLYKIQENMRYGCASGY 122
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 84.0 bits (206), Expect = 2e-16
Identities = 78/275 (28%), Positives = 116/275 (42%), Gaps = 46/275 (16%)
Query: 17 NGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE---TPSGSYWDYIHCT 73
N + K C P G+ H N + G +Y C+E F +PS + C
Sbjct: 1901 NCRRKSCGPPPEPFNGMVHINTDTQF-----GSTVNYSCNEGFRLIGSPSTT------CL 1949
Query: 74 QNG----WSPAVPCLRKCYF---PYLENG-YNQNYGRKFVQGNSTEVACHPGYGLPK--- 122
+G W P P + NG + N F G CH G +
Sbjct: 1950 VSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFE 2009
Query: 123 --AQTTVTCTEKG-----WS-PTPRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQY 173
+ ++ CT K WS P PRCI C+ E+EN + + S + L + I++
Sbjct: 2010 LVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAP--EVENAIRVPGNRSFFTLTEIIRF 2067
Query: 174 KCKPGYATADGNSSGSITCLQNG-WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVP 231
+C+PG+ S ++ C NG W + P C S C PPP I +G+ T + P
Sbjct: 2068 RCQPGFVMV---GSHTVQCQTNGRWGPKLPHC---SRVCQPPPEILHGEHTLSHQDNFSP 2121
Query: 232 QSRVEYQCQPYYELQGSNYVTCS-NGEWS-EPPRC 264
V Y C+P Y+L+G+ + C+ G+WS E PRC
Sbjct: 2122 GQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 2156
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/244 (27%), Positives = 113/244 (46%), Gaps = 32/244 (13%)
Query: 90 PYLENGYNQNYGRK-FVQGNSTEVACHPGYGLPKA-----QTTVTCTEKG-----WS-PT 137
P + NG + R+ F G+ C+PG G K + ++ CT WS P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 138 PRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ-N 195
P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ + C N
Sbjct: 230 PQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFVM---KGPRRVKCQALN 284
Query: 196 GWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS 254
W + P C S C PPP + + + T + P V Y C+P Y+L+G+ + C+
Sbjct: 285 KWEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 255 -NGEWS-EPPRC-IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTS 311
G+WS P C + C ++ M + L GR + G ++F+C G+ S
Sbjct: 342 PQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 395
Query: 312 ILSF 315
S+
Sbjct: 396 SASY 399
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/244 (27%), Positives = 113/244 (46%), Gaps = 32/244 (13%)
Query: 90 PYLENGYNQNYGRK-FVQGNSTEVACHPGYGLPKA-----QTTVTCTEKG-----WS-PT 137
P + NG + R+ F G+ C+PG G K + ++ CT WS P
Sbjct: 620 PTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 679
Query: 138 PRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ-N 195
P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ + C N
Sbjct: 680 PQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFVM---KGPRRVKCQALN 734
Query: 196 GWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS 254
W + P C S C PPP + + + T + P V Y C+P Y+L+G+ + C+
Sbjct: 735 KWEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 255 -NGEWS-EPPRC-IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTS 311
G+WS P C + C ++ M + L GR + G ++F+C G+ S
Sbjct: 792 PQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 845
Query: 312 ILSF 315
S+
Sbjct: 846 SASY 849
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/244 (27%), Positives = 113/244 (46%), Gaps = 32/244 (13%)
Query: 90 PYLENGYNQNYGRK-FVQGNSTEVACHPGYGLPKA-----QTTVTCTEKG-----WS-PT 137
P + NG + R+ F G+ C+PG G K + ++ CT WS P
Sbjct: 1070 PTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 1129
Query: 138 PRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ-N 195
P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ + C N
Sbjct: 1130 PQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFVM---KGPRRVKCQALN 1184
Query: 196 GWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS 254
W + P C S C PPP + + + T + P V Y C+P Y+L+G+ + C+
Sbjct: 1185 KWEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 1241
Query: 255 -NGEWS-EPPRC-IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTS 311
G+WS P C + C ++ M + L GR + G ++F+C G+ S
Sbjct: 1242 PQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 1295
Query: 312 ILSF 315
S+
Sbjct: 1296 SASY 1299
Score = 75.1 bits (183), Expect = 8e-14
Identities = 94/318 (29%), Positives = 133/318 (41%), Gaps = 52/318 (16%)
Query: 23 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYI-----HCTQ--- 74
C P + G H FP GK +Y CD H + G+ +D I CT
Sbjct: 421 CPSPPVIPNGR-HTGKPLEVFPF--GKTVNYTCDPHPDR--GTSFDLIGESTIRCTSDPQ 475
Query: 75 -NG-WS-PAVPC--LRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGY-GLPKAQT 125
NG WS PA C L C P Q F G S + C P Y G P
Sbjct: 476 GNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRP---F 532
Query: 126 TVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
++TC + +P+ + R K+ + NG + + I + I Y C G+ G+
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLI-GH 590
Query: 186 SSGSITCLQNG----WSAQP-ICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ 240
SS C+ +G WS +P IC CG PP I+NGD S + + S V Y+C
Sbjct: 591 SSAE--CILSGNAAHWSTKPPIC--QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCN 646
Query: 241 P------YYELQGSNYVTCSN-----GEWSEP-PRCIHPCIITEENMNKNNIKLKGRSDR 288
P +EL G + C++ G WS P P+CI P T N+ +N I + SD
Sbjct: 647 PGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV---SDN 702
Query: 289 KYYAKTGDTIEFMCKLGY 306
+ + +EF C+ G+
Sbjct: 703 RSLFSLNEVVEFRCQPGF 720
Score = 75.1 bits (183), Expect = 8e-14
Identities = 94/318 (29%), Positives = 133/318 (41%), Gaps = 52/318 (16%)
Query: 23 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYI-----HCTQ--- 74
C P + G H FP GK +Y CD H + G+ +D I CT
Sbjct: 871 CPSPPVIPNGR-HTGKPLEVFPF--GKTVNYTCDPHPDR--GTSFDLIGESTIRCTSDPQ 925
Query: 75 -NG-WS-PAVPC--LRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGY-GLPKAQT 125
NG WS PA C L C P Q F G S + C P Y G P
Sbjct: 926 GNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRP---F 982
Query: 126 TVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
++TC + +P+ + R K+ + NG + + I + I Y C G+ G+
Sbjct: 983 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLI-GH 1040
Query: 186 SSGSITCLQNG----WSAQP-ICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ 240
SS C+ +G WS +P IC CG PP I+NGD S + + S V Y+C
Sbjct: 1041 SSAE--CILSGNAAHWSTKPPIC--QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCN 1096
Query: 241 P------YYELQGSNYVTCSN-----GEWSEP-PRCIHPCIITEENMNKNNIKLKGRSDR 288
P +EL G + C++ G WS P P+CI P T N+ +N I + SD
Sbjct: 1097 PGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV---SDN 1152
Query: 289 KYYAKTGDTIEFMCKLGY 306
+ + +EF C+ G+
Sbjct: 1153 RSLFSLNEVVEFRCQPGF 1170
Score = 74.3 bits (181), Expect = 1e-13
Identities = 46/137 (33%), Positives = 74/137 (54%), Gaps = 14/137 (10%)
Query: 134 WS-PTPRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSIT 191
WS P P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ +
Sbjct: 1575 WSGPAPQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFVM---KGPRRVK 1629
Query: 192 CLQ-NGWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSN 249
C N W + P C S C PPP I +G+ T + P V Y C+P Y+L+G+
Sbjct: 1630 CQALNKWEPELPSC---SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1686
Query: 250 YVTCS-NGEWS-EPPRC 264
+ C+ G+WS E PRC
Sbjct: 1687 SLHCTPQGDWSPEAPRC 1703
Score = 73.6 bits (179), Expect = 2e-13
Identities = 59/208 (28%), Positives = 92/208 (44%), Gaps = 22/208 (10%)
Query: 75 NGWSPAVP-CLRKCYFP--YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTE 131
N W P +P C R C P L Q F G +C PGY L + ++ CT
Sbjct: 1184 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL-RGAASMRCTP 1242
Query: 132 KG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSI 190
+G WSP V++C ++ NG + ++ L ++ + C G+ ++S +
Sbjct: 1243 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQ-LGAKVDFVCDEGFQLKGSSASYCV 1301
Query: 191 TC-LQNGW-SAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY------ 242
+++ W S+ P+C C PP I NG T L+V+ V Y C P+
Sbjct: 1302 LAGMESLWNSSVPVC--EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTS 1359
Query: 243 YELQGSNYVTCS-----NGEWSEP-PRC 264
++L G + + C+ NG WS P PRC
Sbjct: 1360 FDLIGESTIRCTSDPQGNGVWSSPAPRC 1387
Score = 72.4 bits (176), Expect = 5e-13
Identities = 93/318 (29%), Positives = 133/318 (41%), Gaps = 52/318 (16%)
Query: 23 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYI-----HCTQ--- 74
C P + G H FP GK +Y CD H + G+ +D I CT
Sbjct: 1321 CPSPPVIPNGR-HTGKPLEVFPF--GKAVNYTCDPHPDR--GTSFDLIGESTIRCTSDPQ 1375
Query: 75 -NG-WS-PAVPC--LRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGY-GLPKAQT 125
NG WS PA C L C P Q F G S + C P Y G P
Sbjct: 1376 GNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRP---F 1432
Query: 126 TVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
++TC + +P+ + R K+ + NG + + I + I Y C G+ G+
Sbjct: 1433 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLI-GH 1490
Query: 186 SSGSITCLQNG----WSAQP-ICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC- 239
SS C+ +G WS +P IC CG PP I+NGD S + + S V Y+C
Sbjct: 1491 SSAE--CILSGNTAHWSTKPPIC--QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCN 1546
Query: 240 -----QPYYELQGSNYVTCSN-----GEWSEP-PRCIHPCIITEENMNKNNIKLKGRSDR 288
+ +EL G + C++ G WS P P+CI P T N+ +N I + SD
Sbjct: 1547 LGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV---SDN 1602
Query: 289 KYYAKTGDTIEFMCKLGY 306
+ + +EF C+ G+
Sbjct: 1603 RSLFSLNEVVEFRCQPGF 1620
Score = 68.9 bits (167), Expect = 6e-12
Identities = 87/302 (28%), Positives = 121/302 (40%), Gaps = 50/302 (16%)
Query: 41 PYFPVAVGKYYSYYCDEHFE---TPSGSYWDYIHCTQ----NG-WSPAVP---------- 82
P + GK SY CD H + T + I CT NG WS P
Sbjct: 1786 PSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGH 1845
Query: 83 CLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEK-GWSPTPRCI 141
C FP+ N +F G S C PGY +++C E WS
Sbjct: 1846 CKTPEQFPFASPTIPIN-DFEFPVGTSLNYECRPGYF--GKMFSISCLENLVWSSVEDNC 1902
Query: 142 RVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG----W 197
R ++C E NG + ++ + Y C G+ S S TCL +G W
Sbjct: 1903 RRKSCGPPP-EPFNGMVHINTDTQ-FGSTVNYSCNEGFRLI---GSPSTTCLVSGNNVTW 1957
Query: 198 SAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC------QPYYELQGSNY 250
+ PIC S C PPP ISNGD S + + V YQC + +EL G
Sbjct: 1958 DKKAPICEIIS--CEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERS 2015
Query: 251 VTCSN-----GEWSE-PPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKL 304
+ C++ G WS PPRCI T + +N I++ G +R ++ T + I F C+
Sbjct: 2016 IYCTSKDDQVGVWSSPPPRCISTNKCTAPEV-ENAIRVPG--NRSFFTLT-EIIRFRCQP 2071
Query: 305 GY 306
G+
Sbjct: 2072 GF 2073
Score = 66.2 bits (160), Expect = 4e-11
Identities = 65/223 (29%), Positives = 96/223 (43%), Gaps = 33/223 (14%)
Query: 103 KFVQGNSTEVACHPGY-GLPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISE 160
+F G C PGY G P ++ C + W+ R ++C + NG +
Sbjct: 62 EFPIGTYLNYECRPGYSGRP---FSIICLKNSVWTGAKDRCRRKSCRNPPDPV-NGMVHV 117
Query: 161 SSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG----WSAQ-PICINSSEKCGPPPP 215
I +I+Y C GY S S TC+ +G W + PIC CG PP
Sbjct: 118 IKGIQF-GSQIKYSCTKGYRLI---GSSSATCIISGDTVIWDNETPIC--DRIPCGLPPT 171
Query: 216 ISNGDTTSFLLKVYVPQSRVEYQCQP------YYELQGSNYVTCSN-----GEWSEP-PR 263
I+NGD S + + S V Y+C P +EL G + C++ G WS P P+
Sbjct: 172 ITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 264 CIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
CI P T N+ +N I + SD + + +EF C+ G+
Sbjct: 232 CIIPNKCTPPNV-ENGILV---SDNRSLFSLNEVVEFRCQPGF 270
Score = 63.5 bits (153), Expect = 2e-10
Identities = 56/209 (26%), Positives = 92/209 (44%), Gaps = 24/209 (11%)
Query: 75 NGWSPAVP-CLRKCYFP--YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTE 131
N W P +P C R C P L + ++ F G +C PGY L + ++ CT
Sbjct: 1634 NKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDL-RGAASLHCTP 1692
Query: 132 KG-WSP-TPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGS 189
+G WSP PRC V++C ++ +G + ++ L ++ + C G+ + S
Sbjct: 1693 QGDWSPEAPRC-AVKSCDDFLGQLPHGRVLFPLNLQ-LGAKVSFVCDEGFRLKGSSVSHC 1750
Query: 190 ITC-LQNGW-SAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY----- 242
+ +++ W ++ P+C + C PP I NG T + Y C P+
Sbjct: 1751 VLVGMRSLWNNSVPVCEHIF--CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1808
Query: 243 -YELQGSNYVTCS-----NGEWSEP-PRC 264
+ L G + + C+ NG WS P PRC
Sbjct: 1809 TFNLIGESTIRCTSDPHGNGVWSSPAPRC 1837
Score = 58.5 bits (140), Expect = 8e-09
Identities = 73/266 (27%), Positives = 105/266 (39%), Gaps = 35/266 (13%)
Query: 20 VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG--- 76
VK CD D G L H + P + +G S+ CDE F S HC G
Sbjct: 2158 VKSCD--DFL-GQLPHGRVLLP-LNLQLGAKVSFVCDEGFRLKGRSA---SHCVLAGMKA 2210
Query: 77 -WSPAVPCLRKCYFPY---LENGYNQNYGRKFVQ---GNSTEVAC--HPGYGLPK---AQ 124
W+ +VP + + P + NG ++ G F G AC HP G+ +
Sbjct: 2211 LWNSSVPVCEQIFCPNPPAILNG--RHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 2268
Query: 125 TTVTCTEKG-----WS-PTPRC-IRVRTCSKSDIEIENG-FISESSSIYILNKEIQYKCK 176
+++ CT WS P PRC + V +I+NG +I S+Y+ I Y C
Sbjct: 2269 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 2328
Query: 177 PGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVE 236
PGY G I C G +Q C P ++ + KVY V
Sbjct: 2329 PGYLLV---GKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVT 2385
Query: 237 YQCQPYYELQGSNYVTCSNGEWSEPP 262
+C+ Y L+GS + C + +PP
Sbjct: 2386 LKCEDGYTLEGSPWSQCQADDRWDPP 2411
Score = 54.3 bits (129), Expect = 1e-07
Identities = 78/313 (24%), Positives = 118/313 (37%), Gaps = 46/313 (14%)
Query: 26 PDIKHGG--LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG-WSPAVP 82
P+I HG L H++ P G+ Y C+ ++ + +HCT G WSP P
Sbjct: 2104 PEILHGEHTLSHQDNFSP------GQEVFYSCEPSYDLRGAAS---LHCTPQGDWSPEAP 2154
Query: 83 CLRKCYFPYLENGYNQ-NYGRKFVQ-----GNSTEVACHPGYGLPKAQTTVTCTEKG--- 133
+C ++ Q +GR + G C G+ L K ++ C G
Sbjct: 2155 ---RCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRL-KGRSASHCVLAGMKA 2210
Query: 134 -W-SPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGY---ATADGNSSG 188
W S P C ++ C + KEI Y C T +
Sbjct: 2211 LWNSSVPVCEQI-FCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGES 2269
Query: 189 SITCLQ----NG-WSAQ-PIC-INSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQP 241
SI C NG WS+ P C ++ C PP I NG + +Y+P + Y C P
Sbjct: 2270 SIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDP 2329
Query: 242 YYELQGSNYVTCSN-GEWSEPPRCIHPC--IITEENMNKNNIKLKGRSDRKYYAKTGDTI 298
Y L G ++ C++ G WS+ H C + + N I + + Y+ GD +
Sbjct: 2330 GYLLVGKGFIFCTDQGIWSQ---LDHYCKEVNCSFPLFMNGISKELEMKKVYH--YGDYV 2384
Query: 299 EFMCKLGYNANTS 311
C+ GY S
Sbjct: 2385 TLKCEDGYTLEGS 2397
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 84.0 bits (206), Expect = 2e-16
Identities = 78/275 (28%), Positives = 116/275 (42%), Gaps = 46/275 (16%)
Query: 17 NGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE---TPSGSYWDYIHCT 73
N + K C P G+ H N + G +Y C+E F +PS + C
Sbjct: 1451 NCRRKSCGPPPEPFNGMVHINTDTQF-----GSTVNYSCNEGFRLIGSPSTT------CL 1499
Query: 74 QNG----WSPAVPCLRKCYF---PYLENG-YNQNYGRKFVQGNSTEVACHPGYGLPK--- 122
+G W P P + NG + N F G CH G +
Sbjct: 1500 VSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFE 1559
Query: 123 --AQTTVTCTEKG-----WS-PTPRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQY 173
+ ++ CT K WS P PRCI C+ E+EN + + S + L + I++
Sbjct: 1560 LVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAP--EVENAIRVPGNRSFFTLTEIIRF 1617
Query: 174 KCKPGYATADGNSSGSITCLQNG-WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVP 231
+C+PG+ S ++ C NG W + P C S C PPP I +G+ T + P
Sbjct: 1618 RCQPGFVMV---GSHTVQCQTNGRWGPKLPHC---SRVCQPPPEILHGEHTLSHQDNFSP 1671
Query: 232 QSRVEYQCQPYYELQGSNYVTCS-NGEWS-EPPRC 264
V Y C+P Y+L+G+ + C+ G+WS E PRC
Sbjct: 1672 GQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/244 (27%), Positives = 113/244 (46%), Gaps = 32/244 (13%)
Query: 90 PYLENGYNQNYGRK-FVQGNSTEVACHPGYGLPKA-----QTTVTCTEKG-----WS-PT 137
P + NG + R+ F G+ C+PG G K + ++ CT WS P
Sbjct: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 138 PRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ-N 195
P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ + C N
Sbjct: 230 PQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFVM---KGPRRVKCQALN 284
Query: 196 GWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS 254
W + P C S C PPP + + + T + P V Y C+P Y+L+G+ + C+
Sbjct: 285 KWEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 255 -NGEWS-EPPRC-IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTS 311
G+WS P C + C ++ M + L GR + G ++F+C G+ S
Sbjct: 342 PQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 395
Query: 312 ILSF 315
S+
Sbjct: 396 SASY 399
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/244 (27%), Positives = 113/244 (46%), Gaps = 32/244 (13%)
Query: 90 PYLENGYNQNYGRK-FVQGNSTEVACHPGYGLPKA-----QTTVTCTEKG-----WS-PT 137
P + NG + R+ F G+ C+PG G K + ++ CT WS P
Sbjct: 620 PTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 679
Query: 138 PRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQ-N 195
P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ + C N
Sbjct: 680 PQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFVM---KGPRRVKCQALN 734
Query: 196 GWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS 254
W + P C S C PPP + + + T + P V Y C+P Y+L+G+ + C+
Sbjct: 735 KWEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 255 -NGEWS-EPPRC-IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTS 311
G+WS P C + C ++ M + L GR + G ++F+C G+ S
Sbjct: 792 PQGDWSPAAPTCEVKSC---DDFMGQ---LLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 845
Query: 312 ILSF 315
S+
Sbjct: 846 SASY 849
Score = 75.1 bits (183), Expect = 8e-14
Identities = 94/318 (29%), Positives = 133/318 (41%), Gaps = 52/318 (16%)
Query: 23 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYI-----HCTQ--- 74
C P + G H FP GK +Y CD H + G+ +D I CT
Sbjct: 421 CPSPPVIPNGR-HTGKPLEVFPF--GKTVNYTCDPHPDR--GTSFDLIGESTIRCTSDPQ 475
Query: 75 -NG-WS-PAVPC--LRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGY-GLPKAQT 125
NG WS PA C L C P Q F G S + C P Y G P
Sbjct: 476 GNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRP---F 532
Query: 126 TVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
++TC + +P+ + R K+ + NG + + I + I Y C G+ G+
Sbjct: 533 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLI-GH 590
Query: 186 SSGSITCLQNG----WSAQP-ICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ 240
SS C+ +G WS +P IC CG PP I+NGD S + + S V Y+C
Sbjct: 591 SSAE--CILSGNAAHWSTKPPIC--QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCN 646
Query: 241 P------YYELQGSNYVTCSN-----GEWSEP-PRCIHPCIITEENMNKNNIKLKGRSDR 288
P +EL G + C++ G WS P P+CI P T N+ +N I + SD
Sbjct: 647 PGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV---SDN 702
Query: 289 KYYAKTGDTIEFMCKLGY 306
+ + +EF C+ G+
Sbjct: 703 RSLFSLNEVVEFRCQPGF 720
Score = 74.3 bits (181), Expect = 1e-13
Identities = 46/137 (33%), Positives = 74/137 (54%), Gaps = 14/137 (10%)
Query: 134 WS-PTPRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSIT 191
WS P P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ +
Sbjct: 1125 WSGPAPQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFVM---KGPRRVK 1179
Query: 192 CLQ-NGWSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSN 249
C N W + P C S C PPP I +G+ T + P V Y C+P Y+L+G+
Sbjct: 1180 CQALNKWEPELPSC---SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1236
Query: 250 YVTCS-NGEWS-EPPRC 264
+ C+ G+WS E PRC
Sbjct: 1237 SLHCTPQGDWSPEAPRC 1253
Score = 73.6 bits (179), Expect = 2e-13
Identities = 59/208 (28%), Positives = 92/208 (44%), Gaps = 22/208 (10%)
Query: 75 NGWSPAVP-CLRKCYFP--YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTE 131
N W P +P C R C P L Q F G +C PGY L + ++ CT
Sbjct: 734 NKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL-RGAASMRCTP 792
Query: 132 KG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSI 190
+G WSP V++C ++ NG + ++ L ++ + C G+ ++S +
Sbjct: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQ-LGAKVDFVCDEGFQLKGSSASYCV 851
Query: 191 TC-LQNGW-SAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY------ 242
+++ W S+ P+C C PP I NG T L+V+ V Y C P+
Sbjct: 852 LAGMESLWNSSVPVC--EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTS 909
Query: 243 YELQGSNYVTCS-----NGEWSEP-PRC 264
++L G + + C+ NG WS P PRC
Sbjct: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRC 937
Score = 72.4 bits (176), Expect = 5e-13
Identities = 93/318 (29%), Positives = 133/318 (41%), Gaps = 52/318 (16%)
Query: 23 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYI-----HCTQ--- 74
C P + G H FP GK +Y CD H + G+ +D I CT
Sbjct: 871 CPSPPVIPNGR-HTGKPLEVFPF--GKAVNYTCDPHPDR--GTSFDLIGESTIRCTSDPQ 925
Query: 75 -NG-WS-PAVPC--LRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGY-GLPKAQT 125
NG WS PA C L C P Q F G S + C P Y G P
Sbjct: 926 GNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRP---F 982
Query: 126 TVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
++TC + +P+ + R K+ + NG + + I + I Y C G+ G+
Sbjct: 983 SITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLI-GH 1040
Query: 186 SSGSITCLQNG----WSAQP-ICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC- 239
SS C+ +G WS +P IC CG PP I+NGD S + + S V Y+C
Sbjct: 1041 SSAE--CILSGNTAHWSTKPPIC--QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCN 1096
Query: 240 -----QPYYELQGSNYVTCSN-----GEWSEP-PRCIHPCIITEENMNKNNIKLKGRSDR 288
+ +EL G + C++ G WS P P+CI P T N+ +N I + SD
Sbjct: 1097 LGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV---SDN 1152
Query: 289 KYYAKTGDTIEFMCKLGY 306
+ + +EF C+ G+
Sbjct: 1153 RSLFSLNEVVEFRCQPGF 1170
Score = 68.9 bits (167), Expect = 6e-12
Identities = 87/302 (28%), Positives = 121/302 (40%), Gaps = 50/302 (16%)
Query: 41 PYFPVAVGKYYSYYCDEHFE---TPSGSYWDYIHCTQ----NG-WSPAVP---------- 82
P + GK SY CD H + T + I CT NG WS P
Sbjct: 1336 PSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGH 1395
Query: 83 CLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEK-GWSPTPRCI 141
C FP+ N +F G S C PGY +++C E WS
Sbjct: 1396 CKTPEQFPFASPTIPIN-DFEFPVGTSLNYECRPGYF--GKMFSISCLENLVWSSVEDNC 1452
Query: 142 RVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG----W 197
R ++C E NG + ++ + Y C G+ S S TCL +G W
Sbjct: 1453 RRKSCGPPP-EPFNGMVHINTDTQ-FGSTVNYSCNEGFRLI---GSPSTTCLVSGNNVTW 1507
Query: 198 SAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC------QPYYELQGSNY 250
+ PIC S C PPP ISNGD S + + V YQC + +EL G
Sbjct: 1508 DKKAPICEIIS--CEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERS 1565
Query: 251 VTCSN-----GEWSE-PPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKL 304
+ C++ G WS PPRCI T + +N I++ G +R ++ T + I F C+
Sbjct: 1566 IYCTSKDDQVGVWSSPPPRCISTNKCTAPEV-ENAIRVPG--NRSFFTLT-EIIRFRCQP 1621
Query: 305 GY 306
G+
Sbjct: 1622 GF 1623
Score = 66.2 bits (160), Expect = 4e-11
Identities = 65/223 (29%), Positives = 96/223 (43%), Gaps = 33/223 (14%)
Query: 103 KFVQGNSTEVACHPGY-GLPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISE 160
+F G C PGY G P ++ C + W+ R ++C + NG +
Sbjct: 62 EFPIGTYLNYECRPGYSGRP---FSIICLKNSVWTGAKDRCRRKSCRNPPDPV-NGMVHV 117
Query: 161 SSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG----WSAQ-PICINSSEKCGPPPP 215
I +I+Y C GY S S TC+ +G W + PIC CG PP
Sbjct: 118 IKGIQF-GSQIKYSCTKGYRLI---GSSSATCIISGDTVIWDNETPIC--DRIPCGLPPT 171
Query: 216 ISNGDTTSFLLKVYVPQSRVEYQCQP------YYELQGSNYVTCSN-----GEWSEP-PR 263
I+NGD S + + S V Y+C P +EL G + C++ G WS P P+
Sbjct: 172 ITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 231
Query: 264 CIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
CI P T N+ +N I + SD + + +EF C+ G+
Sbjct: 232 CIIPNKCTPPNV-ENGILV---SDNRSLFSLNEVVEFRCQPGF 270
Score = 63.5 bits (153), Expect = 2e-10
Identities = 56/209 (26%), Positives = 92/209 (44%), Gaps = 24/209 (11%)
Query: 75 NGWSPAVP-CLRKCYFP--YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTE 131
N W P +P C R C P L + ++ F G +C PGY L + ++ CT
Sbjct: 1184 NKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDL-RGAASLHCTP 1242
Query: 132 KG-WSP-TPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGS 189
+G WSP PRC V++C ++ +G + ++ L ++ + C G+ + S
Sbjct: 1243 QGDWSPEAPRC-AVKSCDDFLGQLPHGRVLFPLNLQ-LGAKVSFVCDEGFRLKGSSVSHC 1300
Query: 190 ITC-LQNGW-SAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY----- 242
+ +++ W ++ P+C + C PP I NG T + Y C P+
Sbjct: 1301 VLVGMRSLWNNSVPVCEHIF--CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 243 -YELQGSNYVTCS-----NGEWSEP-PRC 264
+ L G + + C+ NG WS P PRC
Sbjct: 1359 TFNLIGESTIRCTSDPHGNGVWSSPAPRC 1387
Score = 58.5 bits (140), Expect = 8e-09
Identities = 73/266 (27%), Positives = 105/266 (39%), Gaps = 35/266 (13%)
Query: 20 VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG--- 76
VK CD D G L H + P + +G S+ CDE F S HC G
Sbjct: 1708 VKSCD--DFL-GQLPHGRVLLP-LNLQLGAKVSFVCDEGFRLKGRSA---SHCVLAGMKA 1760
Query: 77 -WSPAVPCLRKCYFPY---LENGYNQNYGRKFVQ---GNSTEVAC--HPGYGLPK---AQ 124
W+ +VP + + P + NG ++ G F G AC HP G+ +
Sbjct: 1761 LWNSSVPVCEQIFCPNPPAILNG--RHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 1818
Query: 125 TTVTCTEKG-----WS-PTPRC-IRVRTCSKSDIEIENG-FISESSSIYILNKEIQYKCK 176
+++ CT WS P PRC + V +I+NG +I S+Y+ I Y C
Sbjct: 1819 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 1878
Query: 177 PGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVE 236
PGY G I C G +Q C P ++ + KVY V
Sbjct: 1879 PGYLLV---GKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVT 1935
Query: 237 YQCQPYYELQGSNYVTCSNGEWSEPP 262
+C+ Y L+GS + C + +PP
Sbjct: 1936 LKCEDGYTLEGSPWSQCQADDRWDPP 1961
Score = 54.3 bits (129), Expect = 1e-07
Identities = 78/313 (24%), Positives = 118/313 (37%), Gaps = 46/313 (14%)
Query: 26 PDIKHGG--LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG-WSPAVP 82
P+I HG L H++ P G+ Y C+ ++ + +HCT G WSP P
Sbjct: 1654 PEILHGEHTLSHQDNFSP------GQEVFYSCEPSYDLRGAAS---LHCTPQGDWSPEAP 1704
Query: 83 CLRKCYFPYLENGYNQ-NYGRKFVQ-----GNSTEVACHPGYGLPKAQTTVTCTEKG--- 133
+C ++ Q +GR + G C G+ L K ++ C G
Sbjct: 1705 ---RCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRL-KGRSASHCVLAGMKA 1760
Query: 134 -W-SPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGY---ATADGNSSG 188
W S P C ++ C + KEI Y C T +
Sbjct: 1761 LWNSSVPVCEQI-FCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGES 1819
Query: 189 SITCLQ----NG-WSAQ-PIC-INSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQP 241
SI C NG WS+ P C ++ C PP I NG + +Y+P + Y C P
Sbjct: 1820 SIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDP 1879
Query: 242 YYELQGSNYVTCSN-GEWSEPPRCIHPC--IITEENMNKNNIKLKGRSDRKYYAKTGDTI 298
Y L G ++ C++ G WS+ H C + + N I + + Y+ GD +
Sbjct: 1880 GYLLVGKGFIFCTDQGIWSQ---LDHYCKEVNCSFPLFMNGISKELEMKKVYH--YGDYV 1934
Query: 299 EFMCKLGYNANTS 311
C+ GY S
Sbjct: 1935 TLKCEDGYTLEGS 1947
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 81.6 bits (200), Expect = 9e-16
Identities = 79/273 (28%), Positives = 126/273 (46%), Gaps = 34/273 (12%)
Query: 46 AVGKYYSYYCDEHFETPSGSYWDYIHCTQNG-WSPA---VPCL--RKCYFPYLENGYNQN 99
A G S+ C E F + + I C + G W+P+ + C+ R P + NGY
Sbjct: 2103 AAGSVVSFKCMEGFVLNTSAK---IECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYAS- 2158
Query: 100 YGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WS-PTPRCIRVRTCSKSDIEIENGF 157
G + G +C+ G+ + K + TC G WS P P C V +C + ++ENGF
Sbjct: 2159 -GSNYSFGAMVAYSCNKGFYI-KGEKKSTCEATGQWSSPIPTCHPV-SCGEPP-KVENGF 2214
Query: 158 ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQPICINSSEKCGPPPPI 216
+ ++ I E++Y+C PGY + S C N W ++ + CG PPPI
Sbjct: 2215 LEHTTG-RIFESEVRYQCNPGYKSV---GSPVFVCQANRHWHSESPLMCVPLDCGKPPPI 2270
Query: 217 SNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWSEP--PRCIHPCIITEE 273
NG +V S+V++ C YEL G + TC +G+W++ P+C+ P E
Sbjct: 2271 QNGFMKGENFEV---GSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM-PAKCPEP 2326
Query: 274 NMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
+ +N + LK + + G + F CK G+
Sbjct: 2327 PLLENQLVLK-----ELTTEVG-VVTFSCKEGH 2353
Score = 75.9 bits (185), Expect = 5e-14
Identities = 64/224 (28%), Positives = 93/224 (41%), Gaps = 36/224 (16%)
Query: 93 ENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDI 151
ENG++ G + G +C GY L T +TC E G W+ + +C K I
Sbjct: 1796 ENGHSS--GEIYTVGAEVTFSCQEGYQL-MGVTKITCLESGEWNHLIPYCKAVSCGKPAI 1852
Query: 152 EIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICINSSEK 209
ENG I E + + ++ Y+C GY A S +CL N WS + P+C K
Sbjct: 1853 P-ENGCIEELA--FTFGSKVTYRCNKGYTLAGDKES---SCLANSSWSHSPPVC--EPVK 1904
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWSEPPRCIH-- 266
C P I+NG ++L S Y C Y LQG + + C ++G W P H
Sbjct: 1905 CSSPENINNG---KYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLV 1961
Query: 267 ----PCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
P I + + NN + +T+ + CK GY
Sbjct: 1962 FCGEPPAIKDAVITGNNFTFR------------NTVTYTCKEGY 1993
Score = 73.6 bits (179), Expect = 2e-13
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 20/184 (10%)
Query: 90 PYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWS-PTPRCIRVRTCSK 148
P NG Q G ++ E C+ G+ L A++ V WS TP C+ VR +
Sbjct: 2837 PVSANG--QVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2894
Query: 149 SDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQ-PICINS 206
++ NG ++E Y KE+ + C GY + + +TC +G W A+ P+C
Sbjct: 2895 P--QLANG-VTEGLD-YGFMKEVTFHCHEGYIL---HGAPKLTCQSDGNWDAEIPLC--K 2945
Query: 207 SEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRC 264
CGPP +++G F ++ ++YQC P Y+L G++ C SNG WS P C
Sbjct: 2946 PVNCGPPEDLAHGFPNGF---SFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC 3002
Query: 265 IHPC 268
+ PC
Sbjct: 3003 L-PC 3005
Score = 71.6 bits (174), Expect = 9e-13
Identities = 72/269 (26%), Positives = 106/269 (39%), Gaps = 34/269 (12%)
Query: 53 YYCDEHFETPSGSYWDYIHCTQNG-WSPAV-PCLRKCYFPYLENGYNQNYG-------RK 103
YYC + + S + C G W P + +C + E + +Y K
Sbjct: 2045 YYCSDGYSLADNSQ---LLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAK 2101
Query: 104 FVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WSPTP---RCIRVRTCSKSDIEIENGFIS 159
F G+ C G+ L + C G W+P+P +CI VR C + I NG+ S
Sbjct: 2102 FAAGSVVSFKCMEGFVL-NTSAKIECMRGGQWNPSPMSIQCIPVR-CGEPP-SIMNGYAS 2158
Query: 160 ESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNG 219
S+ Y + Y C G+ S TC G + PI CG PP + NG
Sbjct: 2159 GSN--YSFGAMVAYSCNKGFYIKGEKKS---TCEATGQWSSPIPTCHPVSCGEPPKVENG 2213
Query: 220 DTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEW-SEPPRCIHPCIITEENMNK 277
+++ +S V YQC P Y+ GS C +N W SE P P + +
Sbjct: 2214 FLEHTTGRIF--ESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQ 2271
Query: 278 NNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
N +KG + + G ++F C GY
Sbjct: 2272 NGF-MKGEN-----FEVGSKVQFFCNEGY 2294
Score = 66.2 bits (160), Expect = 4e-11
Identities = 64/213 (30%), Positives = 92/213 (43%), Gaps = 26/213 (12%)
Query: 100 YGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WSPT-PRCIRVRTCSKSDIEIENGF 157
+ F+ G C+PGY L + C E G W+ + P CI + C ENGF
Sbjct: 2671 HSSNFLYGTMVSYTCNPGYEL-LGNPVLICQEDGTWNGSAPSCISIE-CDLPTAP-ENGF 2727
Query: 158 ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICINSSEKCGPPPP 215
+ + + + +QY CKPG+ A S CL+N WS A P C + C P P
Sbjct: 2728 LRFTETS--MGSAVQYSCKPGHILA---GSDLRLCLENRKWSGASPRC--EAISCKKPNP 2780
Query: 216 ISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGE-WSE-PPRCIHPCIITEE 273
+ NG Y S + Y+C P Y L G+ TC + + W E P CI P +
Sbjct: 2781 VMNGSIKG---SNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICI-PVDCSSP 2836
Query: 274 NMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
++ N + R D + K IE+ C G+
Sbjct: 2837 PVSANG---QVRGDEYTFQK---EIEYTCNEGF 2863
Score = 63.2 bits (152), Expect = 3e-10
Identities = 63/213 (29%), Positives = 91/213 (42%), Gaps = 26/213 (12%)
Query: 72 CTQNG-WSPAVP-CLR-KCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVT 128
C NG WS + P CL +C P +E Y G F G + + C G+ L + +T
Sbjct: 2989 CLSNGSWSGSSPSCLPCRCSTPVIE--YGTVNGTDFDCGKAARIQCFKGFKL-LGLSEIT 3045
Query: 129 CTEKG-WSPT-PRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNS 186
C G WS P C +C + I N FISE+SS I Y C+ GY
Sbjct: 3046 CEADGQWSSGFPHCEHT-SCGSLPM-IPNAFISETSSWK--ENVITYSCRSGYVI---QG 3098
Query: 187 SGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQ 246
S + C + G +QP + CG PP ++N T + + +S V+ +C Y +
Sbjct: 3099 SSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATG---EAHTYESEVKLRCLEGYTMD 3155
Query: 247 -GSNYVTC-SNGEW------SEPPRCIHPCIIT 271
++ TC +G W P +C P IT
Sbjct: 3156 TDTDTFTCQKDGRWFPERISCSPKKCPLPENIT 3188
Score = 58.5 bits (140), Expect = 8e-09
Identities = 46/165 (27%), Positives = 66/165 (40%), Gaps = 13/165 (7%)
Query: 107 GNSTEVACHPGYGLPKAQTTVTCTEKG-WS-PTPRCIRVRTCSKSDIEIENGFISESSSI 164
G + +C+ GY L + + CTE G WS P P C + C + EN +SE
Sbjct: 3318 GPNVVYSCNRGYSL-EGPSEAHCTENGTWSHPVPLC-KPNPCPVPFVIPENALLSEKE-- 3373
Query: 165 YILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSF 224
+ +++ + KC+ G+ G ITC + Q CGPP + N
Sbjct: 3374 FYVDQNVSIKCREGFLL---QGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGV 3430
Query: 225 LLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWSEPPRCIHPC 268
Y + Y C Y L+G C NG W+ PP C C
Sbjct: 3431 H---YQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVC 3472
Score = 55.1 bits (131), Expect = 9e-08
Identities = 59/219 (26%), Positives = 91/219 (41%), Gaps = 40/219 (18%)
Query: 48 GKYYSYYCDEHFETPSGSYWDYIHCTQNG-WSPAVP-CLR-KCYFPY-LENGYNQNYGRK 103
G + +CD F+ +C G W+ +P C R C P LENG++
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQ---YCLNQGQWTQPLPHCERISCGVPPPLENGFHS--ADD 1705
Query: 104 FVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WSP-TPRCIRVRTCSKSDIEIENGFISES 161
F G++ C+ GY L + + CT+ G W+ +P C+ V C+ E+
Sbjct: 1706 FYAGSTVTYQCNNGYYL-LGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNV 1764
Query: 162 SSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDT 221
YI + C P Y T DG + A+PI KC P NG +
Sbjct: 1765 DGSYICS------CVPPY-TGDGKNC-----------AEPI------KCKAPGNPENGHS 1800
Query: 222 TSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS 259
+ ++Y + V + CQ Y+L G +TC +GEW+
Sbjct: 1801 SG---EIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWN 1836
Score = 52.8 bits (125), Expect = 4e-07
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 30/205 (14%)
Query: 72 CTQNG-WSPAVPCLR--KCYFPY-LENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTV 127
C +G W +P + C P L +G+ + F+ G + C PGY L +
Sbjct: 2931 CQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFS--FIHGGHIQYQCFPGYKLHGNSSRR 2988
Query: 128 TCTEKGWS-PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNS 186
+ WS +P C+ R CS IE + + + + + K + +C G+
Sbjct: 2989 CLSNGSWSGSSPSCLPCR-CSTPVIE----YGTVNGTDFDCGKAARIQCFKGFKLL---G 3040
Query: 187 SGSITCLQNG-WSAQ-PICINSSEKCGPPPPISN---GDTTSFLLKVYVPQSRVEYQCQP 241
ITC +G WS+ P C ++S CG P I N +T+S+ ++ + Y C+
Sbjct: 3041 LSEITCEADGQWSSGFPHCEHTS--CGSLPMIPNAFISETSSW------KENVITYSCRS 3092
Query: 242 YYELQGSNYVTCS-NGEWSEP-PRC 264
Y +QGS+ + C+ G WS+P P C
Sbjct: 3093 GYVIQGSSDLICTEKGVWSQPYPVC 3117
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/252 (24%), Positives = 91/252 (36%), Gaps = 41/252 (16%)
Query: 72 CTQNG-WSPAVPCLRKCYF---PYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTV 127
CT+ G WS P P + N G + ++ C GY + T
Sbjct: 3104 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 3161
Query: 128 TCTEKG-WSPTPRCIRVRTCSKSDIEIENGF--ISESSSIYILNKEIQYKCKPGYATADG 184
TC + G W P R+ +CS + I + +N+++ C GY
Sbjct: 3162 TCQKDGRWFPE----RI-SCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGV 3216
Query: 185 NSSGSITCLQNGWSAQPICINSSE--KCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY 242
N S C +G P S CG P +G Y +S + YQC+P
Sbjct: 3217 NIS---VCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVG---SKYTFESTIIYQCEPG 3270
Query: 243 YELQGSNYVTC-SNGEWS------EPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTG 295
YEL+G+ C N +WS + RC P L G++D + TG
Sbjct: 3271 YELEGNRERVCQENRQWSGGVAICKETRCETPLEF-----------LNGKADIE-NRTTG 3318
Query: 296 DTIEFMCKLGYN 307
+ + C GY+
Sbjct: 3319 PNVVYSCNRGYS 3330
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/236 (26%), Positives = 94/236 (39%), Gaps = 23/236 (9%)
Query: 72 CTQNG-WSPAVP-CLR-KCYFPY-LENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTV 127
C +G WS +P C+ +C P + NG G ++ ++ C PG+ L TT
Sbjct: 2422 CQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYL--STALYTCKPGFELV-GNTTT 2478
Query: 128 TCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNS 186
C E G W + C K EI NG S + Y + + Y C G+
Sbjct: 2479 LCGENGHWLGGKPTCKAIECLKPK-EILNGKFSYTDLHY--GQTVTYSCNRGFRL---EG 2532
Query: 187 SGSITCLQNG-WSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYEL 245
++TCL+ G W N+ C P PI NG Y + + Y C P +++
Sbjct: 2533 PSALTCLETGDWDVDAPSCNAIH-CDSPQPIENGFVEG---ADYSYGAIIIYSCFPGFQV 2588
Query: 246 QGSNYVTCSNGEWSEP-PRCIH-PCIITEENMNKNNIKLKGRSDRKYYAKTGDTIE 299
G TC WS P C+ C + + KLK D+ Y+ + D +E
Sbjct: 2589 AGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLK--DDQGYFEQEDDMME 2642
Score = 47.4 bits (111), Expect = 2e-05
Identities = 55/228 (24%), Positives = 82/228 (35%), Gaps = 23/228 (10%)
Query: 52 SYYCDEHFETPSGSYWDYIHCTQNG-WSPAVPCLRKCYF---PYLENGYNQNYGRKFVQG 107
SY CD + S I CT +G W A P + P +++ G F
Sbjct: 1928 SYSCDTGYSLQGPSI---IECTASGIWDRAPPACHLVFCGEPPAIKDAVIT--GNNFTFR 1982
Query: 108 NSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYIL 167
N+ C GY L T + WS + + +C + I S ++ +
Sbjct: 1983 NTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIV---DHASPETAHRLF 2039
Query: 168 NKEIQYKCKPGYATADGNSSGSITCLQNGW-----SAQPICINSSEKCGPPPPISNGDTT 222
Y C GY+ AD +S + Q W P CI + C PP +S
Sbjct: 2040 GDIAFYYCSDGYSLAD--NSQLLCNAQGKWVPPEGQDMPRCI--AHFCEKPPSVSYSILE 2095
Query: 223 SFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWSEPPRCIHPCI 269
S + S V ++C + L S + C G+W+ P I CI
Sbjct: 2096 SVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQ-CI 2142
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 175 CKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSR 234
C PG+ GN CL G QP+ CG PPP+ NG ++ + S
Sbjct: 1658 CDPGFQLV-GNPVQY--CLNQGQWTQPLPHCERISCGVPPPLENGFHSA---DDFYAGST 1711
Query: 235 VEYQCQPYYELQGSNYVTCS-NGEWS-EPPRCI 265
V YQC Y L G + + C+ NG W+ P C+
Sbjct: 1712 VTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCL 1744
Score = 39.3 bits (90), Expect = 0.005
Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 23/153 (15%)
Query: 55 CDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVAC 114
C E + SG + +HC PA+ YF ++N N ++ + V C
Sbjct: 362 CREGYRA-SGQTCELVHC------PALKPPENGYF--IQNTCNNHFNA------ACGVRC 406
Query: 115 HPGYGLPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQY 173
HPG+ L + + C G WS + RVRTC + ++G IS S+ +
Sbjct: 407 HPGFDL-VGSSIILCLPNGLWSGSESYCRVRTCPHLR-QPKHGHISCSTREMLYKTTCLV 464
Query: 174 KCKPGYATADGNSSGSITCLQNG-WSA-QPICI 204
C GY S +TC N W +P C+
Sbjct: 465 ACDEGYRL---EGSDKLTCQGNSQWDGPEPRCV 494
Score = 38.1 bits (87), Expect = 0.011
Identities = 43/158 (27%), Positives = 68/158 (43%), Gaps = 14/158 (8%)
Query: 154 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPIC-INSSEKC 210
ENG+ +++ N +C PG+ D S I CL NG WS ++ C + +
Sbjct: 385 ENGYFIQNTCNNHFNAACGVRCHPGF---DLVGSSIILCLPNGLWSGSESYCRVRTCPHL 441
Query: 211 GPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWSEP-PRCIHPC 268
P +T +L ++ C Y L+GS+ +TC N +W P PRC+
Sbjct: 442 RQPKHGHISCSTREMLY----KTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERH 497
Query: 269 IITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
T + M K+ I + + K AK G C+ G+
Sbjct: 498 CSTFQ-MPKDVI-ISPHNCGKQPAKFGTICYVSCRQGF 533
Score = 31.2 bits (69), Expect = 1.3
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 11/79 (13%)
Query: 231 PQSRVEYQCQPYYELQGSNYVTCSN-GEWSEP-PRCIH-PCIITEENMNKNNIKLKGRSD 287
P S+V C P ++L G+ C N G+W++P P C C + N + S
Sbjct: 1650 PGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFH------SA 1703
Query: 288 RKYYAKTGDTIEFMCKLGY 306
+YA G T+ + C GY
Sbjct: 1704 DDFYA--GSTVTYQCNNGY 1720
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 79.0 bits (193), Expect = 6e-15
Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 26/245 (10%)
Query: 72 CTQNG-WSPAVP--CLRKCYFPYLE-NGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTV 127
CT NG WS +P + C P + NG YG +V G + C PGY + + +
Sbjct: 3115 CTANGTWSGTLPNCTIISCGDPGIPANGLR--YGDDYVVGQNVSYMCQPGYTMELNGSRI 3172
Query: 128 -TCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
TCT G WS R TC + +I NG + ++ + I Y C PGY + +
Sbjct: 3173 RTCTINGTWSGVMPTCRAVTC-PTPPQISNGRLEGTN--FDWGFSISYICSPGY---ELS 3226
Query: 186 SSGSITCLQNG-WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYY 243
+TC+ NG WS + P C+ + CG P + G K ++ QS V + C +
Sbjct: 3227 FPAVLTCVGNGTWSGEVPQCL--PKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPF 3281
Query: 244 ELQGSNYVTC-SNGEWS-EPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFM 301
L GS+ C ++G WS P CI P T+ + + G + + + G ++F
Sbjct: 3282 ILVGSSTRICQADGTWSGSSPHCIEP---TQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3338
Query: 302 CKLGY 306
CK G+
Sbjct: 3339 CKKGH 3343
Score = 61.6 bits (148), Expect = 9e-10
Identities = 58/166 (34%), Positives = 76/166 (45%), Gaps = 21/166 (12%)
Query: 108 NSTEVACHPGYGLPKAQTTVTCTEKG-WSPT-PRCIRVRTCSKSDIEIENGFISESSSIY 165
+S +C GY L + CT G WS T P C + +C I NG Y
Sbjct: 3095 SSVIYSCMEGYIL-SGPSVRQCTANGTWSGTLPNCTII-SCGDPGIPA-NGL--RYGDDY 3149
Query: 166 ILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICINSSEKCGPPPPISNG--DT 221
++ + + Y C+PGY T + N S TC NG WS P C + C PP ISNG +
Sbjct: 3150 VVGQNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTC--RAVTCPTPPQISNGRLEG 3206
Query: 222 TSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRCI 265
T+F + Y C P YEL +TC NG WS E P+C+
Sbjct: 3207 TNFDWGF-----SISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL 3247
Score = 53.9 bits (128), Expect = 2e-07
Identities = 83/305 (27%), Positives = 116/305 (38%), Gaps = 44/305 (14%)
Query: 17 NGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETP-SGSYWDYIHCTQN 75
N + C P I GL + + VG+ SY C + +GS CT N
Sbjct: 3127 NCTIISCGDPGIPANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSR--IRTCTIN 3178
Query: 76 G-WSPAVPCLRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTE 131
G WS +P R P + NG + G F G S C PGY L +TC
Sbjct: 3179 GTWSGVMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYEL-SFPAVLTCVG 3235
Query: 132 KG-WS-PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGS 189
G WS P+C+ + C I + +I E+ + C + SS
Sbjct: 3236 NGTWSGEVPQCLP-KFCGDPGIPAQG---KREGKSFIYQSEVSFSCNFPFILV--GSSTR 3289
Query: 190 ITCLQNGWS-AQPICIN----SSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYE 244
I WS + P CI S E G P S +T F + S V++ C+ +
Sbjct: 3290 ICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG-----SVVQFHCKKGHL 3344
Query: 245 LQGSNYVTC-SNGEWSE-PPRCI-HPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFM 301
LQGS TC + WS P CI H C E + N + + S G T+ +
Sbjct: 3345 LQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH-------GYTLIYT 3397
Query: 302 CKLGY 306
C+ G+
Sbjct: 3398 CQPGF 3402
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/167 (29%), Positives = 67/167 (40%), Gaps = 16/167 (9%)
Query: 104 FVQGNSTEVACHPGYGLPKAQTTVTCTEKGWS-PTPRCIRVRTCSKSDIEIENGFISESS 162
F G C+PGY L + + W P P CI + C + N +S
Sbjct: 2913 FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI-DCGHPGVP-PNAVLSGEK 2970
Query: 163 SIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICI-NSSEKCGPPPPISNG 219
Y + Y C G + G SS TC NG WS +QP C +++ CG P +G
Sbjct: 2971 --YTFGSTVHYSCT-GKRSLLGQSSR--TCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG 3025
Query: 220 DTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRC 264
+ +S V Y C Y L GS TC +NG W+ P C
Sbjct: 3026 SRQESNFRT---KSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 3069
Score = 49.3 bits (116), Expect = 5e-06
Identities = 56/226 (24%), Positives = 84/226 (37%), Gaps = 37/226 (16%)
Query: 96 YNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTC-TEKGWSPTPRCIRVRTC-------- 146
Y + G F + +C+ GY L + T C + WS P +V C
Sbjct: 2843 YGRTSGNGFNFNDVVTFSCNIGY-LMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPAN 2901
Query: 147 SKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINS 206
SK + +IE+G + + ++ Y C PGY S + C NG +P+
Sbjct: 2902 SKRESKIEHGNFTYGTVVF-------YDCNPGYFLF---GSSVLICQPNGQWDKPLPECI 2951
Query: 207 SEKCG----PPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS-NGEWS-E 260
CG PP + +G+ +F S V Y C L G + TC NG WS
Sbjct: 2952 MIDCGHPGVPPNAVLSGEKYTF-------GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 3004
Query: 261 PPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
P C T + + S+ +T T+ + C GY
Sbjct: 3005 QPHCSGDATGTCGDPGTPGHGSRQESN----FRTKSTVRYACDTGY 3046
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/275 (23%), Positives = 94/275 (34%), Gaps = 89/275 (32%)
Query: 104 FVQGNSTEVACHPGYGLP-KAQTTVTCTEKG-WS---PTPRCIRVRTCSKSDIEIENG-F 157
++ G C+ GY L K TT C G WS TPRC+ V S + +E+G +
Sbjct: 2608 YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRW 2667
Query: 158 ISESSSIYILNKEIQYKCKPGY----------------------------------ATAD 183
+ S Y ++ + C PGY +
Sbjct: 2668 RIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPN 2727
Query: 184 GNSSGSIT-----------------------CLQNG-WS-AQPICINSSEKCGPPPPISN 218
GN G+ T CL +G WS ++ C+ + CG P I N
Sbjct: 2728 GNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL--AGHCGIPELIVN 2785
Query: 219 GDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS------EPPRCIHPCIIT 271
G + Y + V YQC P + L GS+ C + WS P C HP
Sbjct: 2786 GQVIG---ENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP---- 2838
Query: 272 EENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
+ GR+ + D + F C +GY
Sbjct: 2839 -------GSPIYGRTSGNGF-NFNDVVTFSCNIGY 2865
Score = 39.7 bits (91), Expect = 0.004
Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 5/43 (11%)
Query: 231 PQSRVEYQCQPYYELQGSNYVTCSNGE----WS-EPPRCIHPC 268
P V +QC P YELQG +TC E W PP CI PC
Sbjct: 1506 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
Score = 37.0 bits (84), Expect = 0.024
Identities = 48/217 (22%), Positives = 80/217 (36%), Gaps = 45/217 (20%)
Query: 113 ACHPGYGLPKAQTTVTCTEKGW------SPTPRCIRVRTCSKSDIEIENGFISESSSIYI 166
AC G+ L +++ C + + +P P C + +C G ++ Y+
Sbjct: 2555 ACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGGILTTD---YL 2609
Query: 167 LNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLL 226
+ + Y C GY + + ++ WS N + +C ++ SF+L
Sbjct: 2610 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH----NKTPRC---VVVTCPSINSFIL 2662
Query: 227 K----------VYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS---EPPRC-IHPC--I 269
+ Y +++V + C P Y G + C NG WS E P C I C +
Sbjct: 2663 EHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGEL 2722
Query: 270 ITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
T N NK + G T F C LG+
Sbjct: 2723 PTPPNGNKIGTQ----------TSYGSTAIFTCDLGF 2749
Score = 36.6 bits (83), Expect = 0.032
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 5/111 (4%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSE----PPRCI 265
C PPPP+ N + + + + + YQC P + L G+ +TC GE + PP C
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDI-IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
Query: 266 HPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQ 316
C E ++ + L Y + GYN + FQ
Sbjct: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2464
Score = 33.5 bits (75), Expect = 0.27
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 233 SRVEYQCQPYYELQGSNYVTCSNGE---WSEP-PRCIHPC 268
S + Y C P Y L GS+ + C GE W P P CI C
Sbjct: 1335 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1374
Score = 33.5 bits (75), Expect = 0.27
Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 9/67 (13%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSEP------ 261
E C P I NG K+ S V Y C Y LQG + +TC G+ P
Sbjct: 1659 ESCFDPGNIMNGTRLGMDYKL---GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1715
Query: 262 PRCIHPC 268
P C PC
Sbjct: 1716 PSCHAPC 1722
Score = 33.1 bits (74), Expect = 0.35
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 229 YVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PRCIHPC 268
Y+ V +QC Y LQG +++TC G W+ P P C+ C
Sbjct: 2028 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC 2071
Score = 33.1 bits (74), Expect = 0.35
Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PR 263
+ C P P NG + + ++C P Y L G++ +TC +G W+ P PR
Sbjct: 2182 QSCPDPRPFRNGFVIG---NDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
Query: 264 CIHPC 268
C C
Sbjct: 2239 CEALC 2243
Score = 32.0 bits (71), Expect = 0.78
Identities = 53/241 (21%), Positives = 84/241 (34%), Gaps = 39/241 (16%)
Query: 47 VGKYYSYYCDEHFETPSGSYWDYIHCTQN--GWSPAVPCLRKCYFPYLENG-------YN 97
+G +YYCD + S I GW+ A+P C+ P +
Sbjct: 1679 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP---SCHAPCGSRSTGSEGTVLS 1735
Query: 98 QNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGF 157
NY + + G++ C +PK + + +T +E+ +G
Sbjct: 1736 PNYPKNYSVGHN----CVYSIAVPKEFVVFG----------QFVFFQTSLHDVVEVYDGP 1781
Query: 158 ISESSSIYILNKEIQYKCKP----GYATADGNSSGSITCLQNGWSAQPICINSSEKCGPP 213
+SS + L+ + P T S G IT + Q + SS +C
Sbjct: 1782 TQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSV 1841
Query: 214 PPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSEP-PRCIHP 267
P G + S V + C P Y L GS + C S +W++ P CI P
Sbjct: 1842 PEPRFGRRIG---NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1898
Query: 268 C 268
C
Sbjct: 1899 C 1899
Score = 29.6 bits (65), Expect = 3.9
Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 237 YQCQPYYELQGSNYVTCSNG---EWSEP-PRCIHPC 268
+ C Y L+G++ + C G WS P PRC+ C
Sbjct: 1166 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC 1201
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 79.0 bits (193), Expect = 6e-15
Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 26/245 (10%)
Query: 72 CTQNG-WSPAVP--CLRKCYFPYLE-NGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTV 127
CT NG WS +P + C P + NG YG +V G + C PGY + + +
Sbjct: 2986 CTANGTWSGTLPNCTIISCGDPGIPANGLR--YGDDYVVGQNVSYMCQPGYTMELNGSRI 3043
Query: 128 -TCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
TCT G WS R TC + +I NG + ++ + I Y C PGY + +
Sbjct: 3044 RTCTINGTWSGVMPTCRAVTC-PTPPQISNGRLEGTN--FDWGFSISYICSPGY---ELS 3097
Query: 186 SSGSITCLQNG-WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYY 243
+TC+ NG WS + P C+ + CG P + G K ++ QS V + C +
Sbjct: 3098 FPAVLTCVGNGTWSGEVPQCL--PKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPF 3152
Query: 244 ELQGSNYVTC-SNGEWS-EPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFM 301
L GS+ C ++G WS P CI P T+ + + G + + + G ++F
Sbjct: 3153 ILVGSSTRICQADGTWSGSSPHCIEP---TQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3209
Query: 302 CKLGY 306
CK G+
Sbjct: 3210 CKKGH 3214
Score = 61.6 bits (148), Expect = 9e-10
Identities = 58/166 (34%), Positives = 76/166 (45%), Gaps = 21/166 (12%)
Query: 108 NSTEVACHPGYGLPKAQTTVTCTEKG-WSPT-PRCIRVRTCSKSDIEIENGFISESSSIY 165
+S +C GY L + CT G WS T P C + +C I NG Y
Sbjct: 2966 SSVIYSCMEGYIL-SGPSVRQCTANGTWSGTLPNCTII-SCGDPGIPA-NGL--RYGDDY 3020
Query: 166 ILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICINSSEKCGPPPPISNG--DT 221
++ + + Y C+PGY T + N S TC NG WS P C + C PP ISNG +
Sbjct: 3021 VVGQNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTC--RAVTCPTPPQISNGRLEG 3077
Query: 222 TSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRCI 265
T+F + Y C P YEL +TC NG WS E P+C+
Sbjct: 3078 TNFDWGF-----SISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL 3118
Score = 53.9 bits (128), Expect = 2e-07
Identities = 83/305 (27%), Positives = 116/305 (38%), Gaps = 44/305 (14%)
Query: 17 NGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETP-SGSYWDYIHCTQN 75
N + C P I GL + + VG+ SY C + +GS CT N
Sbjct: 2998 NCTIISCGDPGIPANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSR--IRTCTIN 3049
Query: 76 G-WSPAVPCLRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTE 131
G WS +P R P + NG + G F G S C PGY L +TC
Sbjct: 3050 GTWSGVMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYEL-SFPAVLTCVG 3106
Query: 132 KG-WS-PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGS 189
G WS P+C+ + C I + +I E+ + C + SS
Sbjct: 3107 NGTWSGEVPQCLP-KFCGDPGIPAQG---KREGKSFIYQSEVSFSCNFPFILV--GSSTR 3160
Query: 190 ITCLQNGWS-AQPICIN----SSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYE 244
I WS + P CI S E G P S +T F + S V++ C+ +
Sbjct: 3161 ICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG-----SVVQFHCKKGHL 3215
Query: 245 LQGSNYVTC-SNGEWSE-PPRCI-HPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFM 301
LQGS TC + WS P CI H C E + N + + S G T+ +
Sbjct: 3216 LQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH-------GYTLIYT 3268
Query: 302 CKLGY 306
C+ G+
Sbjct: 3269 CQPGF 3273
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/167 (29%), Positives = 67/167 (40%), Gaps = 16/167 (9%)
Query: 104 FVQGNSTEVACHPGYGLPKAQTTVTCTEKGWS-PTPRCIRVRTCSKSDIEIENGFISESS 162
F G C+PGY L + + W P P CI + C + N +S
Sbjct: 2784 FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI-DCGHPGVP-PNAVLSGEK 2841
Query: 163 SIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICI-NSSEKCGPPPPISNG 219
Y + Y C G + G SS TC NG WS +QP C +++ CG P +G
Sbjct: 2842 --YTFGSTVHYSCT-GKRSLLGQSSR--TCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG 2896
Query: 220 DTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRC 264
+ +S V Y C Y L GS TC +NG W+ P C
Sbjct: 2897 SRQESNFRT---KSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 2940
Score = 49.3 bits (116), Expect = 5e-06
Identities = 56/226 (24%), Positives = 84/226 (37%), Gaps = 37/226 (16%)
Query: 96 YNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTC-TEKGWSPTPRCIRVRTC-------- 146
Y + G F + +C+ GY L + T C + WS P +V C
Sbjct: 2714 YGRTSGNGFNFNDVVTFSCNIGY-LMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPAN 2772
Query: 147 SKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINS 206
SK + +IE+G + + ++ Y C PGY S + C NG +P+
Sbjct: 2773 SKRESKIEHGNFTYGTVVF-------YDCNPGYFLF---GSSVLICQPNGQWDKPLPECI 2822
Query: 207 SEKCG----PPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS-NGEWS-E 260
CG PP + +G+ +F S V Y C L G + TC NG WS
Sbjct: 2823 MIDCGHPGVPPNAVLSGEKYTF-------GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 2875
Query: 261 PPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
P C T + + S+ +T T+ + C GY
Sbjct: 2876 QPHCSGDATGTCGDPGTPGHGSRQESN----FRTKSTVRYACDTGY 2917
Score = 47.4 bits (111), Expect = 2e-05
Identities = 58/217 (26%), Positives = 82/217 (37%), Gaps = 38/217 (17%)
Query: 104 FVQGNSTEVACHPGYGLP-KAQTTVTCTEKG-WS---PTPRCIRVRTCSKSDIEIENGFI 158
++ G C+ GY L K TT C G WS TPRC+ V +C + I
Sbjct: 2544 YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCV-VISCGELPTPPNGNKI 2602
Query: 159 SESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICINSSEKCGPPPPI 216
+S + C G+ S CL +G WS ++ C+ + CG P I
Sbjct: 2603 GTQTSY---GSTAIFTCDLGFMLV---GSAVRECLSSGLWSESETRCL--AGHCGIPELI 2654
Query: 217 SNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS------EPPRCIHPCI 269
NG + Y + V YQC P + L GS+ C + WS P C HP
Sbjct: 2655 VNGQVIG---ENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP-- 2709
Query: 270 ITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
+ GR+ + D + F C +GY
Sbjct: 2710 ---------GSPIYGRTSGNGF-NFNDVVTFSCNIGY 2736
Score = 39.7 bits (91), Expect = 0.004
Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 5/43 (11%)
Query: 231 PQSRVEYQCQPYYELQGSNYVTCSNGE----WS-EPPRCIHPC 268
P V +QC P YELQG +TC E W PP CI PC
Sbjct: 1442 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
Score = 36.6 bits (83), Expect = 0.032
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 5/111 (4%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSE----PPRCI 265
C PPPP+ N + + + + + YQC P + L G+ +TC GE + PP C
Sbjct: 2291 CQPPPPVPNAEILTEDDEFEIGDI-IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2349
Query: 266 HPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQ 316
C E ++ + L Y + GYN + FQ
Sbjct: 2350 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2400
Score = 33.5 bits (75), Expect = 0.27
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 233 SRVEYQCQPYYELQGSNYVTCSNGE---WSEP-PRCIHPC 268
S + Y C P Y L GS+ + C GE W P P CI C
Sbjct: 1271 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1310
Score = 33.5 bits (75), Expect = 0.27
Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 9/67 (13%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSEP------ 261
E C P I NG K+ S V Y C Y LQG + +TC G+ P
Sbjct: 1595 ESCFDPGNIMNGTRLGMDYKL---GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1651
Query: 262 PRCIHPC 268
P C PC
Sbjct: 1652 PSCHAPC 1658
Score = 33.1 bits (74), Expect = 0.35
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 229 YVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PRCIHPC 268
Y+ V +QC Y LQG +++TC G W+ P P C+ C
Sbjct: 1964 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC 2007
Score = 33.1 bits (74), Expect = 0.35
Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PR 263
+ C P P NG + + ++C P Y L G++ +TC +G W+ P PR
Sbjct: 2118 QSCPDPRPFRNGFVIG---NDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
Query: 264 CIHPC 268
C C
Sbjct: 2175 CEALC 2179
Score = 32.0 bits (71), Expect = 0.78
Identities = 53/241 (21%), Positives = 84/241 (34%), Gaps = 39/241 (16%)
Query: 47 VGKYYSYYCDEHFETPSGSYWDYIHCTQN--GWSPAVPCLRKCYFPYLENG-------YN 97
+G +YYCD + S I GW+ A+P C+ P +
Sbjct: 1615 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP---SCHAPCGSRSTGSEGTVLS 1671
Query: 98 QNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGF 157
NY + + G++ C +PK + + +T +E+ +G
Sbjct: 1672 PNYPKNYSVGHN----CVYSIAVPKEFVVFG----------QFVFFQTSLHDVVEVYDGP 1717
Query: 158 ISESSSIYILNKEIQYKCKP----GYATADGNSSGSITCLQNGWSAQPICINSSEKCGPP 213
+SS + L+ + P T S G IT + Q + SS +C
Sbjct: 1718 TQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSV 1777
Query: 214 PPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSEP-PRCIHP 267
P G + S V + C P Y L GS + C S +W++ P CI P
Sbjct: 1778 PEPRFGRRIG---NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1834
Query: 268 C 268
C
Sbjct: 1835 C 1835
Score = 29.6 bits (65), Expect = 3.9
Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 237 YQCQPYYELQGSNYVTCSNG---EWSEP-PRCIHPC 268
+ C Y L+G++ + C G WS P PRC+ C
Sbjct: 1102 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC 1137
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 79.0 bits (193), Expect = 6e-15
Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 26/245 (10%)
Query: 72 CTQNG-WSPAVP--CLRKCYFPYLE-NGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTV 127
CT NG WS +P + C P + NG YG +V G + C PGY + + +
Sbjct: 3155 CTANGTWSGTLPNCTIISCGDPGIPANGLR--YGDDYVVGQNVSYMCQPGYTMELNGSRI 3212
Query: 128 -TCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
TCT G WS R TC + +I NG + ++ + I Y C PGY + +
Sbjct: 3213 RTCTINGTWSGVMPTCRAVTC-PTPPQISNGRLEGTN--FDWGFSISYICSPGY---ELS 3266
Query: 186 SSGSITCLQNG-WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYY 243
+TC+ NG WS + P C+ + CG P + G K ++ QS V + C +
Sbjct: 3267 FPAVLTCVGNGTWSGEVPQCL--PKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPF 3321
Query: 244 ELQGSNYVTC-SNGEWS-EPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFM 301
L GS+ C ++G WS P CI P T+ + + G + + + G ++F
Sbjct: 3322 ILVGSSTRICQADGTWSGSSPHCIEP---TQTSCENPGVPRHGSQNNTFGFQVGSVVQFH 3378
Query: 302 CKLGY 306
CK G+
Sbjct: 3379 CKKGH 3383
Score = 61.6 bits (148), Expect = 9e-10
Identities = 58/166 (34%), Positives = 76/166 (45%), Gaps = 21/166 (12%)
Query: 108 NSTEVACHPGYGLPKAQTTVTCTEKG-WSPT-PRCIRVRTCSKSDIEIENGFISESSSIY 165
+S +C GY L + CT G WS T P C + +C I NG Y
Sbjct: 3135 SSVIYSCMEGYIL-SGPSVRQCTANGTWSGTLPNCTII-SCGDPGIPA-NGL--RYGDDY 3189
Query: 166 ILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICINSSEKCGPPPPISNG--DT 221
++ + + Y C+PGY T + N S TC NG WS P C + C PP ISNG +
Sbjct: 3190 VVGQNVSYMCQPGY-TMELNGSRIRTCTINGTWSGVMPTC--RAVTCPTPPQISNGRLEG 3246
Query: 222 TSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRCI 265
T+F + Y C P YEL +TC NG WS E P+C+
Sbjct: 3247 TNFDWGF-----SISYICSPGYELSFPAVLTCVGNGTWSGEVPQCL 3287
Score = 53.9 bits (128), Expect = 2e-07
Identities = 83/305 (27%), Positives = 116/305 (38%), Gaps = 44/305 (14%)
Query: 17 NGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETP-SGSYWDYIHCTQN 75
N + C P I GL + + VG+ SY C + +GS CT N
Sbjct: 3167 NCTIISCGDPGIPANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSR--IRTCTIN 3218
Query: 76 G-WSPAVPCLRKCYFP---YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTE 131
G WS +P R P + NG + G F G S C PGY L +TC
Sbjct: 3219 GTWSGVMPTCRAVTCPTPPQISNGRLE--GTNFDWGFSISYICSPGYEL-SFPAVLTCVG 3275
Query: 132 KG-WS-PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGS 189
G WS P+C+ + C I + +I E+ + C + SS
Sbjct: 3276 NGTWSGEVPQCLP-KFCGDPGIPAQG---KREGKSFIYQSEVSFSCNFPFILV--GSSTR 3329
Query: 190 ITCLQNGWS-AQPICIN----SSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYE 244
I WS + P CI S E G P S +T F + S V++ C+ +
Sbjct: 3330 ICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVG-----SVVQFHCKKGHL 3384
Query: 245 LQGSNYVTC-SNGEWSE-PPRCI-HPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFM 301
LQGS TC + WS P CI H C E + N + + S G T+ +
Sbjct: 3385 LQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSH-------GYTLIYT 3437
Query: 302 CKLGY 306
C+ G+
Sbjct: 3438 CQPGF 3442
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/167 (29%), Positives = 67/167 (40%), Gaps = 16/167 (9%)
Query: 104 FVQGNSTEVACHPGYGLPKAQTTVTCTEKGWS-PTPRCIRVRTCSKSDIEIENGFISESS 162
F G C+PGY L + + W P P CI + C + N +S
Sbjct: 2953 FTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI-DCGHPGVP-PNAVLSGEK 3010
Query: 163 SIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICI-NSSEKCGPPPPISNG 219
Y + Y C G + G SS TC NG WS +QP C +++ CG P +G
Sbjct: 3011 --YTFGSTVHYSCT-GKRSLLGQSSR--TCQLNGHWSGSQPHCSGDATGTCGDPGTPGHG 3065
Query: 220 DTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRC 264
+ +S V Y C Y L GS TC +NG W+ P C
Sbjct: 3066 SRQESNFRT---KSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 3109
Score = 49.3 bits (116), Expect = 5e-06
Identities = 56/226 (24%), Positives = 84/226 (37%), Gaps = 37/226 (16%)
Query: 96 YNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTC-TEKGWSPTPRCIRVRTC-------- 146
Y + G F + +C+ GY L + T C + WS P +V C
Sbjct: 2883 YGRTSGNGFNFNDVVTFSCNIGY-LMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPAN 2941
Query: 147 SKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINS 206
SK + +IE+G + + ++ Y C PGY S + C NG +P+
Sbjct: 2942 SKRESKIEHGNFTYGTVVF-------YDCNPGYFLF---GSSVLICQPNGQWDKPLPECI 2991
Query: 207 SEKCG----PPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS-NGEWS-E 260
CG PP + +G+ +F S V Y C L G + TC NG WS
Sbjct: 2992 MIDCGHPGVPPNAVLSGEKYTF-------GSTVHYSCTGKRSLLGQSSRTCQLNGHWSGS 3044
Query: 261 PPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
P C T + + S+ +T T+ + C GY
Sbjct: 3045 QPHCSGDATGTCGDPGTPGHGSRQESN----FRTKSTVRYACDTGY 3086
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/275 (23%), Positives = 94/275 (34%), Gaps = 89/275 (32%)
Query: 104 FVQGNSTEVACHPGYGLP-KAQTTVTCTEKG-WS---PTPRCIRVRTCSKSDIEIENG-F 157
++ G C+ GY L K TT C G WS TPRC+ V S + +E+G +
Sbjct: 2648 YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRW 2707
Query: 158 ISESSSIYILNKEIQYKCKPGY----------------------------------ATAD 183
+ S Y ++ + C PGY +
Sbjct: 2708 RIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPN 2767
Query: 184 GNSSGSIT-----------------------CLQNG-WS-AQPICINSSEKCGPPPPISN 218
GN G+ T CL +G WS ++ C+ + CG P I N
Sbjct: 2768 GNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL--AGHCGIPELIVN 2825
Query: 219 GDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS------EPPRCIHPCIIT 271
G + Y + V YQC P + L GS+ C + WS P C HP
Sbjct: 2826 GQVIG---ENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHP---- 2878
Query: 272 EENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
+ GR+ + D + F C +GY
Sbjct: 2879 -------GSPIYGRTSGNGF-NFNDVVTFSCNIGY 2905
Score = 39.7 bits (91), Expect = 0.004
Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 5/43 (11%)
Query: 231 PQSRVEYQCQPYYELQGSNYVTCSNGE----WS-EPPRCIHPC 268
P V +QC P YELQG +TC E W PP CI PC
Sbjct: 1546 PGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1588
Score = 37.0 bits (84), Expect = 0.024
Identities = 48/217 (22%), Positives = 80/217 (36%), Gaps = 45/217 (20%)
Query: 113 ACHPGYGLPKAQTTVTCTEKGW------SPTPRCIRVRTCSKSDIEIENGFISESSSIYI 166
AC G+ L +++ C + + +P P C + +C G ++ Y+
Sbjct: 2595 ACDRGFRLV-GKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGGILTTD---YL 2649
Query: 167 LNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLL 226
+ + Y C GY + + ++ WS N + +C ++ SF+L
Sbjct: 2650 VGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH----NKTPRC---VVVTCPSINSFIL 2702
Query: 227 K----------VYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS---EPPRC-IHPC--I 269
+ Y +++V + C P Y G + C NG WS E P C I C +
Sbjct: 2703 EHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGEL 2762
Query: 270 ITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
T N NK + G T F C LG+
Sbjct: 2763 PTPPNGNKIGTQ----------TSYGSTAIFTCDLGF 2789
Score = 36.6 bits (83), Expect = 0.032
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 5/111 (4%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSE----PPRCI 265
C PPPP+ N + + + + + YQC P + L G+ +TC GE + PP C
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDI-IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2453
Query: 266 HPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQ 316
C E ++ + L Y + GYN + FQ
Sbjct: 2454 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQ 2504
Score = 33.5 bits (75), Expect = 0.27
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 233 SRVEYQCQPYYELQGSNYVTCSNGE---WSEP-PRCIHPC 268
S + Y C P Y L GS+ + C GE W P P CI C
Sbjct: 1375 STIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC 1414
Score = 33.5 bits (75), Expect = 0.27
Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 9/67 (13%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSEP------ 261
E C P I NG K+ S V Y C Y LQG + +TC G+ P
Sbjct: 1699 ESCFDPGNIMNGTRLGMDYKL---GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRAL 1755
Query: 262 PRCIHPC 268
P C PC
Sbjct: 1756 PSCHAPC 1762
Score = 33.1 bits (74), Expect = 0.35
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 229 YVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PRCIHPC 268
Y+ V +QC Y LQG +++TC G W+ P P C+ C
Sbjct: 2068 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQC 2111
Score = 33.1 bits (74), Expect = 0.35
Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 7/65 (10%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PR 263
+ C P P NG + + ++C P Y L G++ +TC +G W+ P PR
Sbjct: 2222 QSCPDPRPFRNGFVIG---NDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2278
Query: 264 CIHPC 268
C C
Sbjct: 2279 CEALC 2283
Score = 32.0 bits (71), Expect = 0.78
Identities = 53/241 (21%), Positives = 84/241 (34%), Gaps = 39/241 (16%)
Query: 47 VGKYYSYYCDEHFETPSGSYWDYIHCTQN--GWSPAVPCLRKCYFPYLENG-------YN 97
+G +YYCD + S I GW+ A+P C+ P +
Sbjct: 1719 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP---SCHAPCGSRSTGSEGTVLS 1775
Query: 98 QNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGF 157
NY + + G++ C +PK + + +T +E+ +G
Sbjct: 1776 PNYPKNYSVGHN----CVYSIAVPKEFVVFG----------QFVFFQTSLHDVVEVYDGP 1821
Query: 158 ISESSSIYILNKEIQYKCKP----GYATADGNSSGSITCLQNGWSAQPICINSSEKCGPP 213
+SS + L+ + P T S G IT + Q + SS +C
Sbjct: 1822 TQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSV 1881
Query: 214 PPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSEP-PRCIHP 267
P G + S V + C P Y L GS + C S +W++ P CI P
Sbjct: 1882 PEPRFGRRIG---NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVP 1938
Query: 268 C 268
C
Sbjct: 1939 C 1939
Score = 29.6 bits (65), Expect = 3.9
Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 237 YQCQPYYELQGSNYVTCSNG---EWSEP-PRCIHPC 268
+ C Y L+G++ + C G WS P PRC+ C
Sbjct: 1206 FSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAEC 1241
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 78.2 bits (191), Expect = 1e-14
Identities = 58/191 (30%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 90 PYLENGYNQNYGRKFVQ-GNSTEVACHPGYGLPKA-----QTTVTCTEKG-----WS-PT 137
P + NG + R++ G+ C+ G K + ++ CT K WS P
Sbjct: 162 PTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPA 221
Query: 138 PRCIRVRTCSKSDIEIENGF-ISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG 196
P+CI C+ ++E NG +S++ S++ LN+ ++++C+PG+ G S L N
Sbjct: 222 PQCIIPNKCTPPNVE--NGILVSDNRSLFSLNEVVEFRCQPGFGMK-GPSHVKCQAL-NK 277
Query: 197 WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS- 254
W + P C S C PPP + + + T + P V Y C+P Y+L+GS Y+ C+
Sbjct: 278 WEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTP 334
Query: 255 NGEWS-EPPRC 264
G+WS PRC
Sbjct: 335 QGDWSPAAPRC 345
Score = 68.2 bits (165), Expect = 1e-11
Identities = 69/255 (27%), Positives = 112/255 (43%), Gaps = 27/255 (10%)
Query: 23 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQ-NGWSPAV 81
C P++++G L +N R F ++ + + C F S+ + C N W P +
Sbjct: 230 CTPPNVENGILVSDN--RSLF--SLNEVVEFRCQPGFGMKGPSH---VKCQALNKWEPEL 282
Query: 82 P-CLRKCYFP--YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WSP- 136
P C R C P L Q F G +C PGY L + T + CT +G WSP
Sbjct: 283 PSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL-RGSTYLHCTPQGDWSPA 341
Query: 137 TPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC-LQN 195
PRC V++C ++ NG + ++ L ++ + C G+ ++S + +++
Sbjct: 342 APRC-EVKSCDDFLGQLPNGHVLFPLNLQ-LGAKVDFVCDEGFQLKGSSASYCVLAGMES 399
Query: 196 GW-SAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC- 253
W S+ P+C S C PP NG + ++V SR+ Y C + L G + C
Sbjct: 400 LWNSSVPVCERKS--CETPPVPVNG-MVHVITDIHV-GSRINYSCTTGHRLIGHSSAECI 455
Query: 254 ---SNGEWS-EPPRC 264
+ WS +PP C
Sbjct: 456 LSGNTAHWSMKPPIC 470
Score = 63.9 bits (154), Expect = 2e-10
Identities = 76/269 (28%), Positives = 111/269 (41%), Gaps = 44/269 (16%)
Query: 26 PDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG-WSPAVP-C 83
PD+ H E +R + G+ Y C+ ++ +Y +HCT G WSPA P C
Sbjct: 293 PDVLHA----ERTQRDKDNFSPGQEVFYSCEPGYDLRGSTY---LHCTPQGDWSPAAPRC 345
Query: 84 -LRKC--YFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG----W-S 135
++ C + L NG+ + G + C G+ L K + C G W S
Sbjct: 346 EVKSCDDFLGQLPNGHVL-FPLNLQLGAKVDFVCDEGFQL-KGSSASYCVLAGMESLWNS 403
Query: 136 PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN 195
P C R ++C + + NG + + I++ I Y C G+ G+SS C+ +
Sbjct: 404 SVPVCER-KSCETPPVPV-NGMVHVITDIHV-GSRINYSCTTGHRLI-GHSSAE--CILS 457
Query: 196 G----WSAQP-ICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY------YE 244
G WS +P IC C PP I NG T L V Y C P+ +
Sbjct: 458 GNTAHWSMKPPIC--QQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFN 515
Query: 245 LQGSNYVTCS-----NGEWSEP-PRCIHP 267
L G + + + NG WS P PRC P
Sbjct: 516 LIGESTIRRTSEPHGNGVWSSPAPRCELP 544
Score = 63.5 bits (153), Expect = 2e-10
Identities = 63/223 (28%), Positives = 95/223 (42%), Gaps = 33/223 (14%)
Query: 103 KFVQGNSTEVACHPGY-GLPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISE 160
+F G C PGY G P ++ C + W+ + ++C + NG
Sbjct: 54 EFPIGTYLNYECRPGYSGRP---FSIICLKNSVWTSAKDKCKRKSCRNPPDPV-NGMAHV 109
Query: 161 SSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG----WSAQ-PICINSSEKCGPPPP 215
I +I+Y C GY S S TC+ +G W + P+C CG PP
Sbjct: 110 IKDIQF-RSQIKYSCPKGYRLI---GSSSATCIISGNTVIWDNKTPVCDRII--CGLPPT 163
Query: 216 ISNGDTTSFLLKVYVPQSRVEYQC------QPYYELQGSNYVTCSN-----GEWSEP-PR 263
I+NGD TS + + S V Y C + +EL G + C++ G WS P P+
Sbjct: 164 IANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQ 223
Query: 264 CIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
CI P T N+ +N I + SD + + +EF C+ G+
Sbjct: 224 CIIPNKCTPPNV-ENGILV---SDNRSLFSLNEVVEFRCQPGF 262
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 71.2 bits (173), Expect = 1e-12
Identities = 71/269 (26%), Positives = 116/269 (43%), Gaps = 25/269 (9%)
Query: 55 CDEHFETPSGSYWDYIHCTQNG-WSPAVPCLRKCYF---PYLENGYNQNY-GRKFVQGNS 109
C + ++ +G + +NG W +P + + P + NG + F+ GN
Sbjct: 685 CQDGYQL-TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNE 743
Query: 110 TEVACHPG-YGLPKAQTTVTCTEKG---WS-PTPRCIRVRTCSKS-DIEIENGF-ISESS 162
C G Y L + + KG WS P+P+C+R ++ + E+++G+ ++++
Sbjct: 744 VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTH 803
Query: 163 SIYILNKEIQYKCKPGYATADGNSSGSITC-LQNGW-SAQPICINSSE-KCGPPPPISNG 219
S Y N + C PG+ N S I C N W P CI + C PPP NG
Sbjct: 804 SAYSHNDIVYVDCNPGFIM---NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 860
Query: 220 DTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSN-GEWSEP-PRCIHPCIITEENMNK 277
+ T + + P + Y C Y L G + C++ G WS+P P C + +M+
Sbjct: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920
Query: 278 NNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
KG RK Y + G + C+ GY
Sbjct: 921 IQ---KGLEPRKMY-QYGAVVTLECEDGY 945
Score = 65.9 bits (159), Expect = 5e-11
Identities = 67/265 (25%), Positives = 115/265 (43%), Gaps = 39/265 (14%)
Query: 70 IHCTQNG-WSPAVP-CLRKCYFP-YLENGYNQN-YGRKFVQGNSTEVACHPGYGLPKAQT 125
I C G W P+ P C ++C P + NG ++ + +F G S + +C+PGY L +
Sbjct: 391 IRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVL-VGEE 449
Query: 126 TVTCTEKG-WS-PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATAD 183
++ CT +G W+ P P+C +V C + ++ +++ ++ ++ C GY
Sbjct: 450 SIQCTSEGVWTPPVPQC-KVAACEATGRQL----LTKPQHQFV-RPDVNSSCGEGY---- 499
Query: 184 GNSSGSITCLQNG---WSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ 240
SGS+ G W + I + C PPP I NG T L+ + + V Y C
Sbjct: 500 -KLSGSVYQECQGTIPWFME-IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCN 557
Query: 241 P------YYELQGSNYVTCSN-----GEWSEPPRCIHPCIITEENMN---KNNIKLKGRS 286
P + L G + + C++ G WS P ++ + + N K+ G+
Sbjct: 558 PGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKE 617
Query: 287 DRKYYAKTGDTIEFMCKLGYNANTS 311
+Y DT+ F C G+ S
Sbjct: 618 APYFY---NDTVTFKCYSGFTLKGS 639
Score = 55.5 bits (132), Expect = 7e-08
Identities = 51/222 (22%), Positives = 90/222 (40%), Gaps = 29/222 (13%)
Query: 70 IHCTQNG-----WSPAVPCLR------KCYFPYLENGYNQNYGRK--FVQGNSTEVACHP 116
I CT N WS P + +C ++ NGY + G++ + ++ C+
Sbjct: 574 IRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKIS-GKEAPYFYNDTVTFKCYS 632
Query: 117 GYGLPKAQTTVTC-TEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKC 175
G+ L K + + C + W P TC ++ + S + ++N C
Sbjct: 633 GFTL-KGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQE--LPAGSRVELVNTS----C 685
Query: 176 KPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRV 235
+ GY G++ +NG + I + C PPP I NG T + + ++ + V
Sbjct: 686 QDGYQLT-GHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEV 744
Query: 236 EYQCQPYYELQGSNYVTC-----SNGEWSEP-PRCIHPCIIT 271
Y+C + L G + C +G WS P P+C+ +T
Sbjct: 745 SYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 786
Score = 54.7 bits (130), Expect = 1e-07
Identities = 63/256 (24%), Positives = 96/256 (37%), Gaps = 25/256 (9%)
Query: 90 PYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG----WS-PTPRCIRVR 144
P + NG Y G +C + L ++ + T+ W P P+C
Sbjct: 27 PPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFN 86
Query: 145 TCSKSDIEI-ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN---GWSAQ 200
S I G+ S+ Y + + CK ++ N + S+ C N G +
Sbjct: 87 KYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSM---NGNKSVWCQANNMWGPTRL 143
Query: 201 PICINSSE-KCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEW 258
P C++ +C P I NG TS + P V Y C+ Y L G + C S+G+W
Sbjct: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
Query: 259 SE-PPRCIHPCIITEENMNKNNIKL-KGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQ 316
S PP C EE K+ + G+ + G T F C GY S
Sbjct: 204 SAVPPTC-------EEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRC 256
Query: 317 AVCREGI--VEYPRCE 330
+ +G+ + P CE
Sbjct: 257 VIAGQGVAWTKMPVCE 272
Score = 53.1 bits (126), Expect = 3e-07
Identities = 61/247 (24%), Positives = 90/247 (36%), Gaps = 43/247 (17%)
Query: 47 VGKYYSYYCDEHFET---PS--------GSYWDYIHCTQNGWSPAVPCLRKCYFPYLENG 95
VG +++CDE + PS G W + + + P+ P P L
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPP-------PILNGR 286
Query: 96 YNQNYGRKFVQGNSTEVACHPG---------YGLPKAQTTVTCTEKG-WS-PTPRC---I 141
+ N G+ C P G + TV + G WS P PRC
Sbjct: 287 HIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELST 346
Query: 142 RVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-A 199
C I + +S Y N + + C G+ S I C G W +
Sbjct: 347 SAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGFTL---KGSKQIRCNAQGTWEPS 402
Query: 200 QPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEW 258
P+C ++C PP I NG + + P + ++Y C P Y L G + C S G W
Sbjct: 403 APVC---EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVW 459
Query: 259 SEP-PRC 264
+ P P+C
Sbjct: 460 TPPVPQC 466
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/249 (23%), Positives = 88/249 (35%), Gaps = 29/249 (11%)
Query: 29 KHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG-----WS-PAVP 82
KH G+ EN G SY CD+ F + C + WS P+
Sbjct: 729 KHTGMMAENF-------LYGNEVSYECDQGFYLLGEKK---LQCRSDSKGHGSWSGPSPQ 778
Query: 83 CLR-----KCYFPYLENGYNQNYGRKFVQGNS-TEVACHPGYGLPKAQTTVTCTEKGWSP 136
CLR +C P +++GY N N V C+PG+ + ++ T+ W P
Sbjct: 779 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 838
Query: 137 -TPRCIRVRT--CSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL 193
P CI+ C + + + I Y C GY + C
Sbjct: 839 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV---GEALLLCT 895
Query: 194 QNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC 253
G +QP C P + K+Y + V +C+ Y L+GS C
Sbjct: 896 HEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 955
Query: 254 -SNGEWSEP 261
S+ +W+ P
Sbjct: 956 QSDHQWNPP 964
Score = 42.7 bits (99), Expect = 4e-04
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 13/108 (12%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSEP-PR 263
CG PPPI NG + + + V + + Y C + L G + C +G W +P P+
Sbjct: 23 CGSPPPILNGRISYYSTPIAV-GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 264 C--IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNAN 309
C + E + K++G + ++ GD++ F CK ++ N
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRH----GDSVTFACKTNFSMN 125
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/248 (25%), Positives = 87/248 (35%), Gaps = 27/248 (10%)
Query: 37 NMRRPYF--PVAVGKYYSYYCDEHFETPSGSYW-----DYIHCTQNGWSPAVPCLRK--- 86
N R Y+ P+AVG Y C F D + T + +P K
Sbjct: 31 NGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSS 90
Query: 87 CYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPT--PRCIRVR 144
C P + GY + G+S AC + + ++ W PT P C+ V
Sbjct: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVF 150
Query: 145 TCSKSDIE-IENG-FISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQP 201
+ I NG SE+ + Y C+ GY I CL +G WSA P
Sbjct: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV---GEKIINCLSSGKWSAVP 207
Query: 202 ICINSSEKCGPPPPISNGDTTS-FLLKVYVPQSRVEYQCQPYYELQG---SNYVTCSNG- 256
+ +C NG +L+V V + C Y LQG S V G
Sbjct: 208 PTCEEA-RCKSLGRFPNGKVKEPPILRVGV---TANFFCDEGYRLQGPPSSRCVIAGQGV 263
Query: 257 EWSEPPRC 264
W++ P C
Sbjct: 264 AWTKMPVC 271
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 71.2 bits (173), Expect = 1e-12
Identities = 71/269 (26%), Positives = 116/269 (43%), Gaps = 25/269 (9%)
Query: 55 CDEHFETPSGSYWDYIHCTQNG-WSPAVPCLRKCYF---PYLENGYNQNY-GRKFVQGNS 109
C + ++ +G + +NG W +P + + P + NG + F+ GN
Sbjct: 744 CQDGYQL-TGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNE 802
Query: 110 TEVACHPG-YGLPKAQTTVTCTEKG---WS-PTPRCIRVRTCSKS-DIEIENGF-ISESS 162
C G Y L + + KG WS P+P+C+R ++ + E+++G+ ++++
Sbjct: 803 VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTH 862
Query: 163 SIYILNKEIQYKCKPGYATADGNSSGSITC-LQNGW-SAQPICINSSE-KCGPPPPISNG 219
S Y N + C PG+ N S I C N W P CI + C PPP NG
Sbjct: 863 SAYSHNDIVYVDCNPGFIM---NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 919
Query: 220 DTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSN-GEWSEP-PRCIHPCIITEENMNK 277
+ T + + P + Y C Y L G + C++ G WS+P P C + +M+
Sbjct: 920 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 979
Query: 278 NNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
KG RK Y + G + C+ GY
Sbjct: 980 IQ---KGLEPRKMY-QYGAVVTLECEDGY 1004
Score = 65.9 bits (159), Expect = 5e-11
Identities = 67/265 (25%), Positives = 115/265 (43%), Gaps = 39/265 (14%)
Query: 70 IHCTQNG-WSPAVP-CLRKCYFP-YLENGYNQN-YGRKFVQGNSTEVACHPGYGLPKAQT 125
I C G W P+ P C ++C P + NG ++ + +F G S + +C+PGY L +
Sbjct: 391 IRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVL-VGEE 449
Query: 126 TVTCTEKG-WS-PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATAD 183
++ CT +G W+ P P+C +V C + ++ +++ ++ ++ C GY
Sbjct: 450 SIQCTSEGVWTPPVPQC-KVAACEATGRQL----LTKPQHQFV-RPDVNSSCGEGY---- 499
Query: 184 GNSSGSITCLQNG---WSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ 240
SGS+ G W + I + C PPP I NG T L+ + + V Y C
Sbjct: 500 -KLSGSVYQECQGTIPWFME-IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCN 557
Query: 241 P------YYELQGSNYVTCSN-----GEWSEPPRCIHPCIITEENMN---KNNIKLKGRS 286
P + L G + + C++ G WS P ++ + + N K+ G+
Sbjct: 558 PGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKE 617
Query: 287 DRKYYAKTGDTIEFMCKLGYNANTS 311
+Y DT+ F C G+ S
Sbjct: 618 APYFY---NDTVTFKCYSGFTLKGS 639
Score = 65.5 bits (158), Expect = 6e-11
Identities = 59/214 (27%), Positives = 92/214 (42%), Gaps = 22/214 (10%)
Query: 70 IHC-TQNGWSPAVP-CLRKCYFPY-LENGYNQNYGRKF-VQGNSTEVACHPGYGLPKAQT 125
I C N W P +P C + C P L +G + F V G + + C PGY L
Sbjct: 642 IRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGY-LLVGNK 700
Query: 126 TVTCTEKG-WSPT-PRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATAD 183
++ C G WSP+ PRC TC ++ + S + ++N C+ GY
Sbjct: 701 SIHCMPSGNWSPSAPRC--EETCQHVRQSLQE--LPAGSRVELVNTS----CQDGYQLT- 751
Query: 184 GNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYY 243
G++ +NG + I + C PPP I NG T + + ++ + V Y+C +
Sbjct: 752 GHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGF 811
Query: 244 ELQGSNYVTC-----SNGEWSEP-PRCIHPCIIT 271
L G + C +G WS P P+C+ +T
Sbjct: 812 YLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 845
Score = 54.7 bits (130), Expect = 1e-07
Identities = 63/256 (24%), Positives = 96/256 (37%), Gaps = 25/256 (9%)
Query: 90 PYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG----WS-PTPRCIRVR 144
P + NG Y G +C + L ++ + T+ W P P+C
Sbjct: 27 PPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFN 86
Query: 145 TCSKSDIEI-ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN---GWSAQ 200
S I G+ S+ Y + + CK ++ N + S+ C N G +
Sbjct: 87 KYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSM---NGNKSVWCQANNMWGPTRL 143
Query: 201 PICINSSE-KCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEW 258
P C++ +C P I NG TS + P V Y C+ Y L G + C S+G+W
Sbjct: 144 PTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKW 203
Query: 259 SE-PPRCIHPCIITEENMNKNNIKL-KGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQ 316
S PP C EE K+ + G+ + G T F C GY S
Sbjct: 204 SAVPPTC-------EEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRC 256
Query: 317 AVCREGI--VEYPRCE 330
+ +G+ + P CE
Sbjct: 257 VIAGQGVAWTKMPVCE 272
Score = 53.1 bits (126), Expect = 3e-07
Identities = 61/247 (24%), Positives = 90/247 (36%), Gaps = 43/247 (17%)
Query: 47 VGKYYSYYCDEHFET---PS--------GSYWDYIHCTQNGWSPAVPCLRKCYFPYLENG 95
VG +++CDE + PS G W + + + P+ P P L
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPP-------PILNGR 286
Query: 96 YNQNYGRKFVQGNSTEVACHPG---------YGLPKAQTTVTCTEKG-WS-PTPRC---I 141
+ N G+ C P G + TV + G WS P PRC
Sbjct: 287 HIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELST 346
Query: 142 RVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-A 199
C I + +S Y N + + C G+ S I C G W +
Sbjct: 347 SAVQCPHPQI-LRGRMVSGQKDRYTYNDTVIFACMFGFTL---KGSKQIRCNAQGTWEPS 402
Query: 200 QPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEW 258
P+C ++C PP I NG + + P + ++Y C P Y L G + C S G W
Sbjct: 403 APVC---EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVW 459
Query: 259 SEP-PRC 264
+ P P+C
Sbjct: 460 TPPVPQC 466
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/249 (23%), Positives = 88/249 (35%), Gaps = 29/249 (11%)
Query: 29 KHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG-----WS-PAVP 82
KH G+ EN G SY CD+ F + C + WS P+
Sbjct: 788 KHTGMMAENF-------LYGNEVSYECDQGFYLLGEKK---LQCRSDSKGHGSWSGPSPQ 837
Query: 83 CLR-----KCYFPYLENGYNQNYGRKFVQGNS-TEVACHPGYGLPKAQTTVTCTEKGWSP 136
CLR +C P +++GY N N V C+PG+ + ++ T+ W P
Sbjct: 838 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 897
Query: 137 -TPRCIRVRT--CSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL 193
P CI+ C + + + I Y C GY + C
Sbjct: 898 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV---GEALLLCT 954
Query: 194 QNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC 253
G +QP C P + K+Y + V +C+ Y L+GS C
Sbjct: 955 HEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 1014
Query: 254 -SNGEWSEP 261
S+ +W+ P
Sbjct: 1015 QSDHQWNPP 1023
Score = 42.7 bits (99), Expect = 4e-04
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 13/108 (12%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSEP-PR 263
CG PPPI NG + + + V + + Y C + L G + C +G W +P P+
Sbjct: 23 CGSPPPILNGRISYYSTPIAV-GTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 264 C--IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNAN 309
C + E + K++G + ++ GD++ F CK ++ N
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRH----GDSVTFACKTNFSMN 125
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/248 (25%), Positives = 87/248 (35%), Gaps = 27/248 (10%)
Query: 37 NMRRPYF--PVAVGKYYSYYCDEHFETPSGSYW-----DYIHCTQNGWSPAVPCLRK--- 86
N R Y+ P+AVG Y C F D + T + +P K
Sbjct: 31 NGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKYSS 90
Query: 87 CYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPT--PRCIRVR 144
C P + GY + G+S AC + + ++ W PT P C+ V
Sbjct: 91 CPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVSVF 150
Query: 145 TCSKSDIE-IENG-FISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSAQP 201
+ I NG SE+ + Y C+ GY I CL +G WSA P
Sbjct: 151 PLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV---GEKIINCLSSGKWSAVP 207
Query: 202 ICINSSEKCGPPPPISNGDTTS-FLLKVYVPQSRVEYQCQPYYELQG---SNYVTCSNG- 256
+ +C NG +L+V V + C Y LQG S V G
Sbjct: 208 PTCEEA-RCKSLGRFPNGKVKEPPILRVGV---TANFFCDEGYRLQGPPSSRCVIAGQGV 263
Query: 257 EWSEPPRC 264
W++ P C
Sbjct: 264 AWTKMPVC 271
Score = 33.9 bits (76), Expect = 0.21
Identities = 55/251 (21%), Positives = 88/251 (35%), Gaps = 21/251 (8%)
Query: 70 IHCTQNG-WSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVT 128
I CT G W+P VP + +FV+ + +C GY L +
Sbjct: 451 IQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS-SCGEGYKLSGSVYQEC 509
Query: 129 CTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNS-- 186
W R + TC + S + + Y C PG S
Sbjct: 510 QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLI 569
Query: 187 -SGSITCLQNG-----WSAQ-PICINS--SEKCGPPPPISNGDTTSFLLKVYVPQSRVEY 237
+I C N WS P+C S + +C I+NG S Y V +
Sbjct: 570 GESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVH-IANGYKISGKEAPYFYNDTVTF 628
Query: 238 QCQPYYELQGSNYVTC-SNGEWS-EPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTG 295
+C + L+GS+ + C ++ W E P C C + ++ + G + +G
Sbjct: 629 KCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGC---QSPPGLHHGRHTG--GNTVFFVSG 683
Query: 296 DTIEFMCKLGY 306
T+++ C GY
Sbjct: 684 MTVDYTCDPGY 694
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 70.9 bits (172), Expect = 2e-12
Identities = 70/251 (27%), Positives = 110/251 (43%), Gaps = 26/251 (10%)
Query: 71 HCTQNG-WSPAVP--CLRKCYFP-YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQT- 125
HCT NG W+ P + C P L NG +G F + C+PGY + +
Sbjct: 3019 HCTANGTWTGTAPDCTIISCGDPGTLANGIQ--FGTDFTFNKTVSYQCNPGYVMEAVTSA 3076
Query: 126 TVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADG 184
T+ CT+ G W+P+ + C + ++NG + S + I Y C GY +
Sbjct: 3077 TIRCTKDGRWNPSKPVCKAVLCPQPP-PVQNGTVEGSD--FRWGSSISYSCMDGYQLSH- 3132
Query: 185 NSSGSITCLQNG-WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY 242
S ++C G W + P C+ CG P + G + K + +S V +QC+
Sbjct: 3133 --SAILSCEGRGVWKGEIPQCLPVF--CGDPGIPAEGRLSG---KSFTYKSEVFFQCKSP 3185
Query: 243 YELQGSNYVTC-SNGEWSE-PPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEF 300
+ L GS+ C ++G WS P CI P T + + ++ S R Y + G T+ F
Sbjct: 3186 FILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQN-SSRGY--EVGSTVFF 3242
Query: 301 MCKLGYNANTS 311
C+ GY+ S
Sbjct: 3243 RCRKGYHIQGS 3253
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/163 (28%), Positives = 74/163 (45%), Gaps = 15/163 (9%)
Query: 108 NSTEVACHPGYGLPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYI 166
+S AC GY T CT G W+ T + +C + NG + + +
Sbjct: 3000 SSVIYACWEGYKTSGLMTR-HCTANGTWTGTAPDCTIISCGDPGT-LANGI--QFGTDFT 3055
Query: 167 LNKEIQYKCKPGYATADGNSSGSITCLQNG-WS-AQPICINSSEKCGPPPPISNGDTTSF 224
NK + Y+C PGY + +S +I C ++G W+ ++P+C + C PPP+ NG
Sbjct: 3056 FNKTVSYQCNPGY-VMEAVTSATIRCTKDGRWNPSKPVC--KAVLCPQPPPVQNGTVEG- 3111
Query: 225 LLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEW-SEPPRCI 265
+ S + Y C Y+L S ++C G W E P+C+
Sbjct: 3112 --SDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL 3152
Score = 55.8 bits (133), Expect = 5e-08
Identities = 61/209 (29%), Positives = 93/209 (44%), Gaps = 20/209 (9%)
Query: 70 IHCTQNG-WSPAVPCLRKCYFPY---LENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQT 125
I CT++G W+P+ P + P ++NG + G F G+S +C GY L +
Sbjct: 3078 IRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVE--GSDFRWGSSISYSCMDGYQLSHS-A 3134
Query: 126 TVTCTEKG-WS-PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATAD 183
++C +G W P+C+ V C I E G +S S Y E+ ++CK +
Sbjct: 3135 ILSCEGRGVWKGEIPQCLPV-FCGDPGIPAE-GRLSGKSFTY--KSEVFFQCKSPFILV- 3189
Query: 184 GNSSGSITCLQNGWSA-QPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPY 242
SS + WS QP CI+ + P P + + + Y S V ++C+
Sbjct: 3190 -GSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSS-RGYEVGSTVFFRCRKG 3247
Query: 243 YELQGSNYVTC-SNGEWSE-PPRCI-HPC 268
Y +QGS TC +N WS CI H C
Sbjct: 3248 YHIQGSTTRTCLANLTWSGIQTECIPHAC 3276
Score = 50.4 bits (119), Expect = 2e-06
Identities = 74/310 (23%), Positives = 114/310 (36%), Gaps = 54/310 (17%)
Query: 19 QVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNG-W 77
Q C P+ G F N + Y C E F+ S + C ++G W
Sbjct: 2492 QAVSCGIPESPGNGSFTGN------EFTLDSKVVYECHEGFKLESSQQATAV-CQEDGLW 2544
Query: 78 SPA--VPCLRKCYFPYLENGYNQNYGRKFVQGNSTE------VACHPGYGLPKAQTTVTC 129
S P + P +E +++ + V G+ E ++C PGY L + + C
Sbjct: 2545 SNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYL-EGWRLLRC 2603
Query: 130 TEKG-WS---PTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGN 185
G W+ P C RV +C NG ++ ++ + + C GY +
Sbjct: 2604 QANGTWNIGDERPSC-RVISCGSLSFP-PNG--NKIGTLTVYGATAIFTCNTGYTLVGSH 2659
Query: 186 SSGSITCLQNG-WS-AQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYY 243
CL NG WS ++ C+ + CG P PI NG + + + V YQC P +
Sbjct: 2660 VR---ECLANGLWSGSETRCL--AGHCGSPDPIVNGHISG---DGFSYRDTVVYQCNPGF 2711
Query: 244 ELQGSNYVTC-SNGEWS------EPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGD 296
L G++ C + +WS P C HP N + L D
Sbjct: 2712 RLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNL------------ND 2759
Query: 297 TIEFMCKLGY 306
+ F C GY
Sbjct: 2760 VVNFTCNTGY 2769
Score = 44.3 bits (103), Expect = 2e-04
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 20/110 (18%)
Query: 167 LNKEIQYKCKPGYATADGNSSGSITCLQN-----GW-SAQPICINSSEKCGPPPPISNGD 220
+ ++ Y CKPGY G+S+ TC +N W S P+C + CG P NG
Sbjct: 2452 VGSKVHYFCKPGYRMV-GHSNA--TCRRNPLGMYQWDSLTPLC--QAVSCGIPESPGNG- 2505
Query: 221 TTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC---SNGEWS---EPPRC 264
SF + S+V Y+C ++L+ S T +G WS +PP C
Sbjct: 2506 --SFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTC 2553
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PR 263
+ C PPP NG + Y V ++C P Y L G +TC +G W+ P PR
Sbjct: 2086 QNCPDPPPFQNG---YMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPR 2142
Query: 264 CIHPC 268
C PC
Sbjct: 2143 CDAPC 2147
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 6/101 (5%)
Query: 229 YVPQSRVEYQCQPYYELQGSNYVTCSNG---EWSEP-PRCIHPCIITEENMNKNNIKLKG 284
Y+ + +QC+P Y LQG ++++C G W+ P P CI C T + + L
Sbjct: 1932 YMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTLSTL--GGVILSP 1989
Query: 285 RSDRKYYAKTGDTIEFMCKLGYNANTSILSFQAVCREGIVE 325
Y T +GY A+ L+F +E
Sbjct: 1990 GFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLE 2030
Score = 36.6 bits (83), Expect = 0.032
Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 4/38 (10%)
Query: 235 VEYQCQPYYELQGSNYVTCSNGE---WSEP-PRCIHPC 268
V Y C P Y + GSN +TC +G+ W +P P CI C
Sbjct: 1241 VLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAEC 1278
Score = 33.1 bits (74), Expect = 0.35
Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
Query: 235 VEYQCQPYYELQGSNYVTC----SNGEWS-EPPRCIHPC 268
V +QC P Y+LQG +TC + W +PP CI C
Sbjct: 1414 VTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAAC 1452
Score = 33.1 bits (74), Expect = 0.35
Identities = 25/114 (21%), Positives = 42/114 (36%), Gaps = 5/114 (4%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEW----SEPPR 263
+KC PPP + + + + V+YQC P Y L G++ +TC P
Sbjct: 2257 KKCQPPPAVPQAEMLTEDDDFEIGDF-VKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPT 2315
Query: 264 CIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQA 317
C C E + + L Y+ + + YN + +FQ+
Sbjct: 2316 CEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQS 2369
Score = 32.0 bits (71), Expect = 0.78
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 6/42 (14%)
Query: 233 SRVEYQCQPYYELQGSNYVTCSN-----GEWSEP-PRCIHPC 268
S V ++C P Y LQGS + C + +W++ P C+ PC
Sbjct: 1762 SIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPC 1803
Score = 31.2 bits (69), Expect = 1.3
Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 5/61 (8%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRCIHP 267
CG P + G T ++ + ++C +EL G +TC N +WS P C+
Sbjct: 528 CGDPGIPAYGKRTG---SSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFS 584
Query: 268 C 268
C
Sbjct: 585 C 585
Score = 30.0 bits (66), Expect = 3.0
Identities = 20/67 (29%), Positives = 27/67 (40%), Gaps = 9/67 (13%)
Query: 208 EKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGEWSEP------ 261
E C P I NG K+ S + YQC Y++ + +TC G +P
Sbjct: 1563 EACFDPGNIMNGTRVGTDFKL---GSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVL 1619
Query: 262 PRCIHPC 268
P C PC
Sbjct: 1620 PSCNAPC 1626
>gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]
Length = 490
Score = 68.9 bits (167), Expect = 6e-12
Identities = 58/196 (29%), Positives = 91/196 (46%), Gaps = 22/196 (11%)
Query: 76 GWSPAVP--CLRK-CYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL--PKAQTTVT-C 129
GW P+ C+++ C P +E+ N + + G + CH G+ + P V+ C
Sbjct: 108 GWIPSDNSICVQEDCRIPQIEDAEIHN--KTYRHGEKLIITCHEGFKIRYPDLHNMVSLC 165
Query: 130 TEKG-WSPTPRCIRVRTCSKSDIEIENGF--ISESSSIYILNKEIQYKCKPGYATADGNS 186
+ G W+ P C + C + + NG+ ISE + + + I Y+C PG+ +
Sbjct: 166 RDDGTWNNLPIC---QGCLRP-LASSNGYVNISELQTSFPVGTVISYRCFPGFKL---DG 218
Query: 187 SGSITCLQNG-WSAQPICINSSEKCGPPPPISNGDTTSF--LLKVYVPQSRVEYQCQPYY 243
S + CLQN WS+ P + E C PP +S+GD + Y + VE+ C P Y
Sbjct: 219 SAYLECLQNLIWSSSPPRCLALEVCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGY 278
Query: 244 ELQGS-NYVTCSNGEW 258
L Y+TC GEW
Sbjct: 279 SLTSDYKYITCQYGEW 294
Score = 35.0 bits (79), Expect = 0.092
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 11/99 (11%)
Query: 47 VGKYYSYYCDEHFETPSGSYWDYIHCTQNG-WSPAVP---CLRKCYFP-YLENGYNQNYG 101
VG SY C F+ +Y + C QN WS + P L C P + +G +
Sbjct: 202 VGTVISYRCFPGFKLDGSAY---LECLQNLIWSSSPPRCLALEVCPLPPMVSHGDFVCHP 258
Query: 102 R---KFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPT 137
R ++ G E C PGY L +TC W P+
Sbjct: 259 RPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPS 297
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 62.0 bits (149), Expect = 7e-10
Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 16/171 (9%)
Query: 105 VQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTP-RCIRVRTCSKSDIEIENGFISESSS 163
++G C PGY L + + WS P C ++ TC+ EI NG + S +
Sbjct: 549 IRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRTASDA 607
Query: 164 IYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQ-PICINSSEKCGPPPPIS 217
+ + +QY+C PGY+ + +TC WS + P C E C P
Sbjct: 608 GFPVGSHVQYRCLPGYSL---EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 664
Query: 218 NGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EW-SEPPRC 264
NG T + +S + + C +EL G +TC G +W S+PP C
Sbjct: 665 NGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 714
Score = 55.1 bits (131), Expect = 9e-08
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 20/163 (12%)
Query: 154 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICINSSEKCGP 212
E G+ + S I + Y+C+PGY S +TC + WSA P C
Sbjct: 537 EWGWRTASHGDLIRGTVLTYQCEPGYELL---GSDILTCQWDLSWSAAPPACQKIMTCAD 593
Query: 213 PPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSE-PPRC-- 264
P I+NG T+ V S V+Y+C P Y L+G+ +TC +WS+ P+C
Sbjct: 594 PGEIANGHRTASDAGFPVG-SHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCAL 652
Query: 265 -IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
PC+ + +N ++ K++ + G+++ F C G+
Sbjct: 653 KYEPCL--NPGVPENGY----QTLYKHHYQAGESLRFFCYEGF 689
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 48 GKYYSYYCDEHFETPSGSYWDYIHCTQN-GWSPAVPCLRK---CYFP-YLENGYNQNYGR 102
G +Y C+ +E D + C + WS A P +K C P + NG+
Sbjct: 551 GTVLTYQCEPGYELLGS---DILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDA 607
Query: 103 KFVQGNSTEVACHPGYGLPKAQTTVTC------TEKGWSPTPRC-IRVRTCSKSDIEIEN 155
F G+ + C PGY L A +TC T K P+C ++ C + EN
Sbjct: 608 GFPVGSHVQYRCLPGYSLEGA-AMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVP-EN 665
Query: 156 GFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL---QNGWSAQP 201
G+ + Y + +++ C G+ +ITC+ + W++QP
Sbjct: 666 GYQTLYKHHYQAGESLRFFCYEGFELI---GEVTITCVPGHPSQWTSQP 711
Score = 35.8 bits (81), Expect = 0.054
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWS-EPPRCI 265
CG PP ++GD + L P + C Y+LQG + C NG W+ E P C+
Sbjct: 176 CGFPPRPAHGDVSVTDLH---PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 232
Query: 266 HPCIITEENMNKNNI 280
C T N I
Sbjct: 233 ASCGGTIHNATLGRI 247
Score = 35.4 bits (80), Expect = 0.071
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 10/75 (13%)
Query: 237 YQCQPYYELQGSNYVTCS-NGEWS-EPPRC--IHPCIITEENMNKNNIKLKGRSDRKYYA 292
YQC+P YEL GS+ +TC + WS PP C I C E N + + SD +
Sbjct: 556 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGH----RTASDAGF-- 609
Query: 293 KTGDTIEFMCKLGYN 307
G +++ C GY+
Sbjct: 610 PVGSHVQYRCLPGYS 624
Score = 30.8 bits (68), Expect = 1.7
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 6/61 (9%)
Query: 86 KCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL-----PKAQTTVTCTEKGWSPT-PR 139
+C+ P+L +G ++ G +C PGY L P A V TE W+ T P
Sbjct: 349 RCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPA 408
Query: 140 C 140
C
Sbjct: 409 C 409
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3
[Homo sapiens]
Length = 840
Score = 62.0 bits (149), Expect = 7e-10
Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 16/171 (9%)
Query: 105 VQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTP-RCIRVRTCSKSDIEIENGFISESSS 163
++G C PGY L + + WS P C ++ TC+ EI NG + S +
Sbjct: 593 IRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRTASDA 651
Query: 164 IYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQ-PICINSSEKCGPPPPIS 217
+ + +QY+C PGY+ + +TC WS + P C E C P
Sbjct: 652 GFPVGSHVQYRCLPGYSL---EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 218 NGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EW-SEPPRC 264
NG T + +S + + C +EL G +TC G +W S+PP C
Sbjct: 709 NGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 55.1 bits (131), Expect = 9e-08
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 20/163 (12%)
Query: 154 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICINSSEKCGP 212
E G+ + S I + Y+C+PGY S +TC + WSA P C
Sbjct: 581 EWGWRTASHGDLIRGTVLTYQCEPGYELL---GSDILTCQWDLSWSAAPPACQKIMTCAD 637
Query: 213 PPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSE-PPRC-- 264
P I+NG T+ V S V+Y+C P Y L+G+ +TC +WS+ P+C
Sbjct: 638 PGEIANGHRTASDAGFPVG-SHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCAL 696
Query: 265 -IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
PC+ + +N ++ K++ + G+++ F C G+
Sbjct: 697 KYEPCL--NPGVPENGY----QTLYKHHYQAGESLRFFCYEGF 733
Score = 43.1 bits (100), Expect = 3e-04
Identities = 45/194 (23%), Positives = 77/194 (39%), Gaps = 23/194 (11%)
Query: 48 GKYYSYYCDEHFETPSGSYWDYIHCTQN-GWSPAVPCLRK---CYFP-YLENGYNQNYGR 102
G +Y C+ +E D + C + WS A P +K C P + NG+
Sbjct: 595 GTVLTYQCEPGYELLGS---DILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDA 651
Query: 103 KFVQGNSTEVACHPGYGLPKAQTTVTC------TEKGWSPTPRC-IRVRTCSKSDIEIEN 155
F G+ + C PGY L A +TC T K P+C ++ C + EN
Sbjct: 652 GFPVGSHVQYRCLPGYSLEGA-AMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVP-EN 709
Query: 156 GFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL---QNGWSAQPICINSSEKCGP 212
G+ + Y + +++ C G+ +ITC+ + W++QP ++ P
Sbjct: 710 GYQTLYKHHYQAGESLRFFCYEGFELI---GEVTITCVPGHPSQWTSQPPLCKVTQTTDP 766
Query: 213 PPPISNGDTTSFLL 226
+ G+ +L
Sbjct: 767 SRQLEGGNLALAIL 780
Score = 35.8 bits (81), Expect = 0.054
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWS-EPPRCI 265
CG PP ++GD + L P + C Y+LQG + C NG W+ E P C+
Sbjct: 220 CGFPPRPAHGDVSVTDLH---PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 266 HPCIITEENMNKNNI 280
C T N I
Sbjct: 277 ASCGGTIHNATLGRI 291
Score = 35.4 bits (80), Expect = 0.071
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 10/75 (13%)
Query: 237 YQCQPYYELQGSNYVTCS-NGEWS-EPPRC--IHPCIITEENMNKNNIKLKGRSDRKYYA 292
YQC+P YEL GS+ +TC + WS PP C I C E N + + SD +
Sbjct: 600 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGH----RTASDAGF-- 653
Query: 293 KTGDTIEFMCKLGYN 307
G +++ C GY+
Sbjct: 654 PVGSHVQYRCLPGYS 668
Score = 30.8 bits (68), Expect = 1.7
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 6/61 (9%)
Query: 86 KCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL-----PKAQTTVTCTEKGWSPT-PR 139
+C+ P+L +G ++ G +C PGY L P A V TE W+ T P
Sbjct: 393 RCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPA 452
Query: 140 C 140
C
Sbjct: 453 C 453
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 62.0 bits (149), Expect = 7e-10
Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 16/171 (9%)
Query: 105 VQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTP-RCIRVRTCSKSDIEIENGFISESSS 163
++G C PGY L + + WS P C ++ TC+ EI NG + S +
Sbjct: 663 IRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRTASDA 721
Query: 164 IYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQ-PICINSSEKCGPPPPIS 217
+ + +QY+C PGY+ + +TC WS + P C E C P
Sbjct: 722 GFPVGSHVQYRCLPGYSL---EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 778
Query: 218 NGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EW-SEPPRC 264
NG T + +S + + C +EL G +TC G +W S+PP C
Sbjct: 779 NGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 828
Score = 55.1 bits (131), Expect = 9e-08
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 20/163 (12%)
Query: 154 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICINSSEKCGP 212
E G+ + S I + Y+C+PGY S +TC + WSA P C
Sbjct: 651 EWGWRTASHGDLIRGTVLTYQCEPGYELL---GSDILTCQWDLSWSAAPPACQKIMTCAD 707
Query: 213 PPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSE-PPRC-- 264
P I+NG T+ V S V+Y+C P Y L+G+ +TC +WS+ P+C
Sbjct: 708 PGEIANGHRTASDAGFPVG-SHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCAL 766
Query: 265 -IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
PC+ + +N ++ K++ + G+++ F C G+
Sbjct: 767 KYEPCL--NPGVPENGY----QTLYKHHYQAGESLRFFCYEGF 803
Score = 43.1 bits (100), Expect = 3e-04
Identities = 45/194 (23%), Positives = 77/194 (39%), Gaps = 23/194 (11%)
Query: 48 GKYYSYYCDEHFETPSGSYWDYIHCTQN-GWSPAVPCLRK---CYFP-YLENGYNQNYGR 102
G +Y C+ +E D + C + WS A P +K C P + NG+
Sbjct: 665 GTVLTYQCEPGYELLGS---DILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDA 721
Query: 103 KFVQGNSTEVACHPGYGLPKAQTTVTC------TEKGWSPTPRC-IRVRTCSKSDIEIEN 155
F G+ + C PGY L A +TC T K P+C ++ C + EN
Sbjct: 722 GFPVGSHVQYRCLPGYSLEGA-AMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVP-EN 779
Query: 156 GFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL---QNGWSAQPICINSSEKCGP 212
G+ + Y + +++ C G+ +ITC+ + W++QP ++ P
Sbjct: 780 GYQTLYKHHYQAGESLRFFCYEGFELI---GEVTITCVPGHPSQWTSQPPLCKVTQTTDP 836
Query: 213 PPPISNGDTTSFLL 226
+ G+ +L
Sbjct: 837 SRQLEGGNLALAIL 850
Score = 35.8 bits (81), Expect = 0.054
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWS-EPPRCI 265
CG PP ++GD + L P + C Y+LQG + C NG W+ E P C+
Sbjct: 290 CGFPPRPAHGDVSVTDLH---PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Query: 266 HPCIITEENMNKNNI 280
C T N I
Sbjct: 347 ASCGGTIHNATLGRI 361
Score = 35.4 bits (80), Expect = 0.071
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 10/75 (13%)
Query: 237 YQCQPYYELQGSNYVTCS-NGEWS-EPPRC--IHPCIITEENMNKNNIKLKGRSDRKYYA 292
YQC+P YEL GS+ +TC + WS PP C I C E N + + SD +
Sbjct: 670 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGH----RTASDAGF-- 723
Query: 293 KTGDTIEFMCKLGYN 307
G +++ C GY+
Sbjct: 724 PVGSHVQYRCLPGYS 738
Score = 30.8 bits (68), Expect = 1.7
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 6/61 (9%)
Query: 86 KCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL-----PKAQTTVTCTEKGWSPT-PR 139
+C+ P+L +G ++ G +C PGY L P A V TE W+ T P
Sbjct: 463 RCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPA 522
Query: 140 C 140
C
Sbjct: 523 C 523
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 62.0 bits (149), Expect = 7e-10
Identities = 48/171 (28%), Positives = 73/171 (42%), Gaps = 16/171 (9%)
Query: 105 VQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTP-RCIRVRTCSKSDIEIENGFISESSS 163
++G C PGY L + + WS P C ++ TC+ EI NG + S +
Sbjct: 593 IRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRTASDA 651
Query: 164 IYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQ-PICINSSEKCGPPPPIS 217
+ + +QY+C PGY+ + +TC WS + P C E C P
Sbjct: 652 GFPVGSHVQYRCLPGYSL---EGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 218 NGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EW-SEPPRC 264
NG T + +S + + C +EL G +TC G +W S+PP C
Sbjct: 709 NGYQTLYKHHYQAGES-LRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLC 758
Score = 55.1 bits (131), Expect = 9e-08
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 20/163 (12%)
Query: 154 ENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQN-GWSAQPICINSSEKCGP 212
E G+ + S I + Y+C+PGY S +TC + WSA P C
Sbjct: 581 EWGWRTASHGDLIRGTVLTYQCEPGYELL---GSDILTCQWDLSWSAAPPACQKIMTCAD 637
Query: 213 PPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEWSE-PPRC-- 264
P I+NG T+ V S V+Y+C P Y L+G+ +TC +WS+ P+C
Sbjct: 638 PGEIANGHRTASDAGFPVG-SHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCAL 696
Query: 265 -IHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
PC+ + +N ++ K++ + G+++ F C G+
Sbjct: 697 KYEPCL--NPGVPENGY----QTLYKHHYQAGESLRFFCYEGF 733
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 48 GKYYSYYCDEHFETPSGSYWDYIHCTQN-GWSPAVPCLRK---CYFP-YLENGYNQNYGR 102
G +Y C+ +E D + C + WS A P +K C P + NG+
Sbjct: 595 GTVLTYQCEPGYELLGS---DILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDA 651
Query: 103 KFVQGNSTEVACHPGYGLPKAQTTVTC------TEKGWSPTPRC-IRVRTCSKSDIEIEN 155
F G+ + C PGY L A +TC T K P+C ++ C + EN
Sbjct: 652 GFPVGSHVQYRCLPGYSLEGA-AMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVP-EN 709
Query: 156 GFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCL---QNGWSAQP 201
G+ + Y + +++ C G+ +ITC+ + W++QP
Sbjct: 710 GYQTLYKHHYQAGESLRFFCYEGFELI---GEVTITCVPGHPSQWTSQP 755
Score = 35.8 bits (81), Expect = 0.054
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 210 CGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNG---EWS-EPPRCI 265
CG PP ++GD + L P + C Y+LQG + C NG W+ E P C+
Sbjct: 220 CGFPPRPAHGDVSVTDLH---PGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Query: 266 HPCIITEENMNKNNI 280
C T N I
Sbjct: 277 ASCGGTIHNATLGRI 291
Score = 35.4 bits (80), Expect = 0.071
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 10/75 (13%)
Query: 237 YQCQPYYELQGSNYVTCS-NGEWS-EPPRC--IHPCIITEENMNKNNIKLKGRSDRKYYA 292
YQC+P YEL GS+ +TC + WS PP C I C E N + + SD +
Sbjct: 600 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGH----RTASDAGF-- 653
Query: 293 KTGDTIEFMCKLGYN 307
G +++ C GY+
Sbjct: 654 PVGSHVQYRCLPGYS 668
Score = 30.8 bits (68), Expect = 1.7
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 6/61 (9%)
Query: 86 KCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL-----PKAQTTVTCTEKGWSPT-PR 139
+C+ P+L +G ++ G +C PGY L P A V TE W+ T P
Sbjct: 393 RCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPA 452
Query: 140 C 140
C
Sbjct: 453 C 453
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 61.2 bits (147), Expect = 1e-09
Identities = 42/186 (22%), Positives = 76/186 (40%), Gaps = 15/186 (8%)
Query: 90 PYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPR-CIRVRTCSK 148
P ++NG+ + V+G C PGY + + T + WS P C ++ C+
Sbjct: 749 PEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTD 808
Query: 149 SDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQ-PI 202
E+++ S + ++ IQY C PG+ S +TC W+++ P
Sbjct: 809 PG-EVDHSTRLISDPVLLVGTTIQYTCNPGFVL---EGSSLLTCYSRETGTPIWTSRLPH 864
Query: 203 CINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSNGE---WS 259
C++ P + ++Y+P + + C +EL G + C G+ W+
Sbjct: 865 CVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWN 924
Query: 260 EP-PRC 264
P P C
Sbjct: 925 GPLPVC 930
Score = 32.7 bits (73), Expect = 0.46
Identities = 17/58 (29%), Positives = 25/58 (43%), Gaps = 4/58 (6%)
Query: 87 CYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTC---TEKGWSPT-PRC 140
CY PY++NG + G E C PG+ L + + C + W+ T P C
Sbjct: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
Score = 30.4 bits (67), Expect = 2.3
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 237 YQCQPYYELQGSNYVTCSNG---EW-SEPPRCIHPC 268
+ C YELQG+ +TC N W S+ P C PC
Sbjct: 417 FHCHLGYELQGAKMLTCINASKPHWSSQEPICSAPC 452
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 58.5 bits (140), Expect = 8e-09
Identities = 78/336 (23%), Positives = 124/336 (36%), Gaps = 63/336 (18%)
Query: 23 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYW---DYIHCTQNG-WS 78
C PD+ HG + G Y+Y F+ G IHC + W+
Sbjct: 239 CRKPDVSHGEMVS----------GFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWN 288
Query: 79 PAVPCLR--KCY-FPYLENGYNQNYGRK-----FVQGNSTEVACHPGYGLPKAQTTVTCT 130
P+ P C P + + + Y R +V G CHPGY + T
Sbjct: 289 PSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVIC 348
Query: 131 EKG--WSPTPRCIRVRTCSKSDIEIENGFISE-------SSSIYILNKEIQYKCKPGYAT 181
+K W+P C C + ++ NG I++ + +Y EI + C
Sbjct: 349 QKNLRWTPYQGC-EALCCPEP--KLNNGEITQHRKSRPANHCVYFYGDEISFSCHE---- 401
Query: 182 ADGNSSGSITCLQNG-WSAQ-PICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQC 239
S S C +G WS + P C + C PP I++G + + + Y+C
Sbjct: 402 ---TSRFSAICQGDGTWSPRTPSC---GDICNFPPKIAHGHYKQSSSYSFFKEEII-YEC 454
Query: 240 QPYYELQGSNYVTCSNGEWSEP-PRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTI 298
Y L G ++CS WS P P+C C E + ++ D+ Y + + +
Sbjct: 455 DKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGRLSV------DKDQYVEP-ENV 507
Query: 299 EFMCKLGYNANTSILSFQAVCREG----IVEYPRCE 330
C GY ++ Q++ G E P+CE
Sbjct: 508 TIQCDSGY----GVVGPQSITCSGNRTWYPEVPKCE 539
Score = 56.6 bits (135), Expect = 3e-08
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 25/239 (10%)
Query: 107 GNSTEVACHPGYGLPKAQTTVTCTEK----GWS-PTPRCIRVRTCSKSDIEIENGFISES 161
G+ E +C G+ L TT C + GWS P P+C V+ K +I NG S
Sbjct: 133 GSQIEFSCSEGFFLI-GSTTSRCEVQDRGVGWSHPLPQCEIVKC--KPPPDIRNGRHSGE 189
Query: 162 SSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-----WSAQPICINSSEKCG-PPPP 215
+ Y + Y C P ++ SI+C W P + EK P
Sbjct: 190 ENFYAYGFSVTYSCDPRFSLL---GHASISCTVENETIGVWRPSP---PTCEKITCRKPD 243
Query: 216 ISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-SNGEWS-EPPRCIHPCIITEE 273
+S+G+ S +Y + + ++CQ + L+GS+ + C ++ +W+ PP C I
Sbjct: 244 VSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLP 303
Query: 274 NMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQAVCREGI--VEYPRCE 330
++ + + R ++ G + + C GY T + +C++ + Y CE
Sbjct: 304 DIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPT-TVICQKNLRWTPYQGCE 361
Score = 55.8 bits (133), Expect = 5e-08
Identities = 58/212 (27%), Positives = 85/212 (40%), Gaps = 18/212 (8%)
Query: 103 KFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISES 161
+F G + + C PGY + T+TC G W CI R + E+ NG + E
Sbjct: 70 RFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKR--CRHPGELRNGQV-EI 126
Query: 162 SSIYILNKEIQYKCKPGYATADGNSSG-SITCLQNGWSAQPICINSSEKCGPPPPISNGD 220
+ +I++ C G+ +S + GWS P+ KC PPP I NG
Sbjct: 127 KTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWS-HPLPQCEIVKCKPPPDIRNG- 184
Query: 221 TTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTC-----SNGEW-SEPPRCIHPCIITEEN 274
S Y V Y C P + L G ++C + G W PP C IT
Sbjct: 185 RHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEK---ITCRK 241
Query: 275 MNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGY 306
+ ++ ++ Y K DTI F C+ G+
Sbjct: 242 PDVSHGEMVSGFGPIYNYK--DTIVFKCQKGF 271
Score = 36.2 bits (82), Expect = 0.041
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 13/128 (10%)
Query: 210 CGPPPPISNGDTTSFLLKV--YVPQSRVEYQCQP-YYELQGSNYVTC-SNGEWSEPPRCI 265
CGPPP +S L + + ++Y C P Y + +TC S+GEW CI
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCI 109
Query: 266 HPCIITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILSFQAVCREGI-- 323
+ + +++K +D + G IEF C G+ S S V G+
Sbjct: 110 YKRCRHPGELRNGQVEIK--TDLSF----GSQIEFSCSEGFFLIGSTTSRCEVQDRGVGW 163
Query: 324 -VEYPRCE 330
P+CE
Sbjct: 164 SHPLPQCE 171
>gi|153266841 apolipoprotein H precursor [Homo sapiens]
Length = 345
Score = 54.3 bits (129), Expect = 1e-07
Identities = 65/255 (25%), Positives = 99/255 (38%), Gaps = 21/255 (8%)
Query: 85 RKCYFP-YLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-WSP-TPRCI 141
R C F LENG + F N+ +C+ G+ L A + CTE+G WSP P C
Sbjct: 82 RVCPFAGILENGAVRY--TTFEYPNTISFSCNTGFYLNGAD-SAKCTEEGKWSPELPVCA 138
Query: 142 RVRTCSKSDI---EIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-W 197
+ C I + + + + ++C P +A GN +ITC +G W
Sbjct: 139 PI-ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF-GND--TITCTTHGNW 194
Query: 198 SAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCSN-G 256
+ P C KC P NG + + + C Y L G + C+ G
Sbjct: 195 TKLPEC--REVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLG 252
Query: 257 EWSEPPRCIHPC--IITEENMNKNNIKLKGRSDRKYYAKTGDTIEFMCKLGYNANTSILS 314
WS P C C + + + ++K + K GD + F CK +
Sbjct: 253 NWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK--NKEKKCSYT 310
Query: 315 FQAVCREGIVEYPRC 329
A C +G +E P+C
Sbjct: 311 EDAQCIDGTIEVPKC 325
Score = 43.1 bits (100), Expect = 3e-04
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 15/146 (10%)
Query: 68 DYIHCTQNG-WSPAVPCLRKCYFPYLE-------NGYNQNYGRKFVQGNSTEVACHPGYG 119
D CT+ G WSP +P P Y + G + ++ C P +
Sbjct: 120 DSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHA 179
Query: 120 LPKAQTTVTCTEKG-WSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKE-IQYKCKP 177
+ T+TCT G W+ P C V+ S +NGF++ + + K+ + C
Sbjct: 180 M-FGNDTITCTTHGNWTKLPECREVKCPFPS--RPDNGFVNYPAKPTLYYKDKATFGCHD 236
Query: 178 GYATADGNSSGSITCLQNGWSAQPIC 203
GY + DG T L N WSA P C
Sbjct: 237 GY-SLDGPEEIECTKLGN-WSAMPSC 260
Score = 35.4 bits (80), Expect = 0.071
Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 12/125 (9%)
Query: 144 RTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPIC 203
RTC K D ++ + + Y +EI Y CKPGY + G I L W PI
Sbjct: 21 RTCPKPD-DLPFSTVVPLKTFYEPGEEITYSCKPGYVSR-GGMRKFICPLTGLW---PI- 74
Query: 204 INSSEKCGPP--PPISNGDTTSFLLKVYVPQSRVEYQCQPYYELQGSNYVTCS-NGEWS- 259
++ KC P P + + + + + + C + L G++ C+ G+WS
Sbjct: 75 --NTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSP 132
Query: 260 EPPRC 264
E P C
Sbjct: 133 ELPVC 137
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 52.8 bits (125), Expect = 4e-07
Identities = 53/191 (27%), Positives = 71/191 (37%), Gaps = 16/191 (8%)
Query: 72 CTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEV-ACHPGYGLPKAQTTVTCT 130
C W + C P L N + K V+G C GY L +T
Sbjct: 8 CLMVAWRVSASDAEHC--PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNA 65
Query: 131 EKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSI 190
K W T R+ C D + NG S S + + +K I + C Y N S
Sbjct: 66 SKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRS--- 119
Query: 191 TCLQNGWSAQPICINSSEKCGPPPPISNG--DTTSFLLKVYVPQSRVEYQCQPYYELQGS 248
CL++ A P I S C PP +G + +F L S + Y C+ Y L G
Sbjct: 120 QCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLG-----STISYYCEDRYYLVGV 174
Query: 249 NYVTCSNGEWS 259
C +GEWS
Sbjct: 175 QEQQCVDGEWS 185
>gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 52.8 bits (125), Expect = 4e-07
Identities = 53/191 (27%), Positives = 71/191 (37%), Gaps = 16/191 (8%)
Query: 72 CTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEV-ACHPGYGLPKAQTTVTCT 130
C W + C P L N + K V+G C GY L +T
Sbjct: 8 CLMVAWRVSASDAEHC--PELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNA 65
Query: 131 EKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSI 190
K W T R+ C D + NG S S + + +K I + C Y N S
Sbjct: 66 SKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDK-ITFMCNDHYILKGSNRS--- 119
Query: 191 TCLQNGWSAQPICINSSEKCGPPPPISNG--DTTSFLLKVYVPQSRVEYQCQPYYELQGS 248
CL++ A P I S C PP +G + +F L S + Y C+ Y L G
Sbjct: 120 QCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLG-----STISYYCEDRYYLVGV 174
Query: 249 NYVTCSNGEWS 259
C +GEWS
Sbjct: 175 QEQQCVDGEWS 185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,817,198
Number of Sequences: 37866
Number of extensions: 803272
Number of successful extensions: 2499
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 1695
Number of HSP's gapped (non-prelim): 430
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.