Guide to the Human Genome
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Search of human proteins with 54607056

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54607056 connexin 31 [Homo sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54607056 connexin 31 [Homo sapiens]                                575   e-164
gi|13128960 connexin 31 [Homo sapiens]                                575   e-164
gi|23397464 gap junction protein, beta 4 [Homo sapiens]               319   1e-87
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]      310   9e-85
gi|42558283 gap junction protein beta 2 [Homo sapiens]                260   8e-70
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]        257   9e-69
gi|159032020 gap junction protein, beta 6 [Homo sapiens]              255   3e-68
gi|158966714 gap junction protein, beta 6 [Homo sapiens]              255   3e-68
gi|158966717 gap junction protein, beta 6 [Homo sapiens]              255   3e-68
gi|40254837 gap junction protein, beta 6 [Homo sapiens]               255   3e-68
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]       249   1e-66
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]         249   1e-66
gi|62865885 connexin 37 [Homo sapiens]                                199   2e-51
gi|55953076 connexin 50 [Homo sapiens]                                190   1e-48
gi|4504001 connexin 43 [Homo sapiens]                                 189   3e-48
gi|22779877 connexin 46 [Homo sapiens]                                186   2e-47
gi|14211941 gap junction protein, alpha 10 [Homo sapiens]             179   2e-45
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]       173   1e-43
gi|32483412 connexin 40 [Homo sapiens]                                161   5e-40
gi|6631083 connexin 40 [Homo sapiens]                                 161   5e-40
gi|122939172 connexin 45 [Homo sapiens]                               138   6e-33
gi|69122473 connexin 45 [Homo sapiens]                                138   6e-33
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]    135   4e-32
gi|145699105 connexin40.1 [Homo sapiens]                              122   4e-28
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]     118   6e-27
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]       107   8e-24
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]       102   4e-22
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]           76   4e-14
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]           76   4e-14
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]           76   4e-14

>gi|54607056 connexin 31 [Homo sapiens]
          Length = 270

 Score =  575 bits (1482), Expect = e-164
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC
Sbjct: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
           TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA
Sbjct: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120

Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180
           GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR
Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180

Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240
           PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR
Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240

Query: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270
           CHHKLVEAGEVDPDPGNNKLQASAPNLTPI
Sbjct: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270


>gi|13128960 connexin 31 [Homo sapiens]
          Length = 270

 Score =  575 bits (1482), Expect = e-164
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC
Sbjct: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
           TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA
Sbjct: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120

Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180
           GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR
Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180

Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240
           PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR
Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240

Query: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270
           CHHKLVEAGEVDPDPGNNKLQASAPNLTPI
Sbjct: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270


>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
          Length = 266

 Score =  319 bits (818), Expect = 1e-87
 Identities = 154/264 (58%), Positives = 187/264 (70%), Gaps = 9/264 (3%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M+W  LQ LLSGVNKYST   RIWLSVVF+FRVLVYVVAAE VW DEQKDF CNTKQPGC
Sbjct: 1   MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
            NVCYD +FP+S++RLWALQLI VTCPSLLV++HVAYREERER+H  KHG     LYDN 
Sbjct: 61  PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120

Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180
            KK GGLWWTYL SLIFK  ++  FLY+ H L+  ++MPR+V C +V PCP+ VDCYI+R
Sbjct: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVAC-SVEPCPHTVDCYISR 179

Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLI---CHRVLRGLHKDKPRGGCSPSSSASRAS 237
           PTEKK+FTYFMV  +A+CI+L + E+ YL+   C  +    H+      C P +      
Sbjct: 180 PTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLPDTCPPYVL 239

Query: 238 TCRCHHK-----LVEAGEVDPDPG 256
           +   H +     L++AG    D G
Sbjct: 240 SQGGHPEDGNSVLMKAGSAPVDAG 263


>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
          Length = 273

 Score =  310 bits (794), Expect = 9e-85
 Identities = 137/240 (57%), Positives = 182/240 (75%), Gaps = 1/240 (0%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M+W   + LLSGVNKYSTAFGRIWLS+VF+FRVLVY+V AERVW D+ KDFDCNT+QPGC
Sbjct: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
           +NVC+D +FP+S++RLWALQLI VTCPSLLV++HVAYRE +E+RHR+ HG+   +LY N 
Sbjct: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120

Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180
           GKK GGLWWTY+ SL+FK  ++  FLY+ H+ +  + +P +V+C +  PCPNIVDC+I++
Sbjct: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKC-HADPCPNIVDCFISK 179

Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240
           P+EK IFT FMV  +A+CI+L + EL YL+  R    L   K +  C+        S+C+
Sbjct: 180 PSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTTSSCK 239


>gi|42558283 gap junction protein beta 2 [Homo sapiens]
          Length = 226

 Score =  260 bits (665), Expect = 8e-70
 Identities = 120/216 (55%), Positives = 160/216 (74%), Gaps = 8/216 (3%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           MDW TLQ +L GVNK+ST+ G+IWL+V+F+FR+++ VVAA+ VWGDEQ DF CNT QPGC
Sbjct: 1   MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
            NVCYD+YFPIS+IRLWALQLIFV+ P+LLV +HVAYR   ++R   K G+  ++  D  
Sbjct: 61  KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIK-GEIKSEFKDIE 119

Query: 121 GKK------HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIV 174
             K       G LWWTY  S+ F++I E  F+Y+ + ++ GF+M RLV+C N  PCPN V
Sbjct: 120 EIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKC-NAWPCPNTV 178

Query: 175 DCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210
           DC+++RPTEK +FT FM+  S +CI+L + ELCYL+
Sbjct: 179 DCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLL 214


>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
          Length = 223

 Score =  257 bits (656), Expect = 9e-69
 Identities = 124/210 (59%), Positives = 157/210 (74%), Gaps = 8/210 (3%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M W  L+ LLSGVNKYST  G IWL+VVFVFR+LVY+VAAE VW DEQK+F+CN++QPGC
Sbjct: 1   MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
            NVC+D++FPIS +RLWALQLI V+ PSLLV+LHVAY E RE+RHR+       KLY + 
Sbjct: 61  KNVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRK-------KLYVSP 113

Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180
           G   GGLW+ YL SLI K   E  FL L + L+ GF++P L++C ++ PCPN VDC+I++
Sbjct: 114 GTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKC-DLKPCPNTVDCFISK 172

Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLI 210
           PTEK IF  F+V  S +CIVL   EL +L+
Sbjct: 173 PTEKTIFILFLVITSCLCIVLNFIELSFLV 202


>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  255 bits (651), Expect = 3e-68
 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           MDW TL   + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119
            NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E  R+ R+       K  ++
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175
             K+     G LWWTY  S+ F++I E  F+Y+ + L++G+++P +++C  + PCPN+VD
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179

Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210
           C+I+RPTEK +FT FM+ AS +C++L + ELCYL+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214


>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  255 bits (651), Expect = 3e-68
 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           MDW TL   + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119
            NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E  R+ R+       K  ++
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175
             K+     G LWWTY  S+ F++I E  F+Y+ + L++G+++P +++C  + PCPN+VD
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179

Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210
           C+I+RPTEK +FT FM+ AS +C++L + ELCYL+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214


>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  255 bits (651), Expect = 3e-68
 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           MDW TL   + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119
            NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E  R+ R+       K  ++
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175
             K+     G LWWTY  S+ F++I E  F+Y+ + L++G+++P +++C  + PCPN+VD
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179

Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210
           C+I+RPTEK +FT FM+ AS +C++L + ELCYL+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214


>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  255 bits (651), Expect = 3e-68
 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           MDW TL   + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119
            NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E  R+ R+       K  ++
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175
             K+     G LWWTY  S+ F++I E  F+Y+ + L++G+++P +++C  + PCPN+VD
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179

Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210
           C+I+RPTEK +FT FM+ AS +C++L + ELCYL+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214


>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  249 bits (637), Expect = 1e-66
 Identities = 116/223 (52%), Positives = 163/223 (73%), Gaps = 11/223 (4%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M+W  L  LLSGVN++STA GR+WLSV+F+FR++V VVAAE VWGDE+  F CNT QPGC
Sbjct: 1   MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERR--HRQKHGDQCAKLYD 118
            +VCYD +FPIS++RLW+LQLI V+ P+LLV +HVA+++  E++    + HGD    L+ 
Sbjct: 61  NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117

Query: 119 NAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173
              K+H     G LWWTY+ S++F+L+ E +F+Y+ + L+ G+ M RLV+C +V PCPN 
Sbjct: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKC-DVYPCPNT 176

Query: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
           VDC+++RPTEK +FT FM+ AS +CI+L + E+ YLI     R
Sbjct: 177 VDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR 219


>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  249 bits (637), Expect = 1e-66
 Identities = 116/223 (52%), Positives = 163/223 (73%), Gaps = 11/223 (4%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M+W  L  LLSGVN++STA GR+WLSV+F+FR++V VVAAE VWGDE+  F CNT QPGC
Sbjct: 1   MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERR--HRQKHGDQCAKLYD 118
            +VCYD +FPIS++RLW+LQLI V+ P+LLV +HVA+++  E++    + HGD    L+ 
Sbjct: 61  NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117

Query: 119 NAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173
              K+H     G LWWTY+ S++F+L+ E +F+Y+ + L+ G+ M RLV+C +V PCPN 
Sbjct: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKC-DVYPCPNT 176

Query: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
           VDC+++RPTEK +FT FM+ AS +CI+L + E+ YLI     R
Sbjct: 177 VDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR 219


>gi|62865885 connexin 37 [Homo sapiens]
          Length = 333

 Score =  199 bits (507), Expect = 2e-51
 Identities = 105/240 (43%), Positives = 145/240 (60%), Gaps = 25/240 (10%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L+ LL  V ++ST  G+IWL+V+F+FR+L+  +A E VWGDEQ DF+CNT QPGCT
Sbjct: 3   DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD---------- 111
           NVCYD  FPIS+IR W LQ +FV+ P+L+ + HV Y   RE R RQK G+          
Sbjct: 63  NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122

Query: 112 ----------QCAKL---YDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNM 158
                     Q AK+    D   +  G L  TY+ S++ K ++E  FLY    L +G+ M
Sbjct: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRL-YGWTM 181

Query: 159 PRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218
             +  C   APCP +VDC+++RPTEK IF  FM+    + +VL + EL +L+C  + RG+
Sbjct: 182 EPVFVCQR-APCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 240


>gi|55953076 connexin 50 [Homo sapiens]
          Length = 433

 Score =  190 bits (482), Expect = 1e-48
 Identities = 100/227 (44%), Positives = 141/227 (62%), Gaps = 21/227 (9%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L  +L  VN++ST  GR+WL+V+F+FR+L+   AAE VWGDEQ DF CNT+QPGC 
Sbjct: 3   DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILH----VAYREERERRHRQKHGDQC---- 113
           NVCYD  FPIS+IRLW LQ+IFV+ PSL+ + H    V   E+R+ R  ++ G Q     
Sbjct: 63  NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122

Query: 114 ----AKLYDNAGKK-------HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLV 162
                 +  ++G K        G L  TY+  +IFK + E  F+ + H   +GF +  L 
Sbjct: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFI-VGHYFLYGFRILPLY 181

Query: 163 QCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
           +C+   PCPN+VDC+++RPTEK IF  FM+  ++V + L + EL +L
Sbjct: 182 RCSR-WPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227


>gi|4504001 connexin 43 [Homo sapiens]
          Length = 382

 Score =  189 bits (479), Expect = 3e-48
 Identities = 105/258 (40%), Positives = 140/258 (54%), Gaps = 30/258 (11%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L  LL  V  YSTA G++WLSV+F+FR+L+   A E  WGDEQ  F CNT+QPGC 
Sbjct: 3   DWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCE 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121
           NVCYD  FPIS++R W LQ+IFV+ P+LL + HV Y   +E +  +K  +      D   
Sbjct: 63  NVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVN 122

Query: 122 -----------------------KKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNM 158
                                  K  GGL  TY+ S++FK I E  FL L+    +GF++
Sbjct: 123 VDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFL-LIQWYIYGFSL 181

Query: 159 PRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218
             +  C    PCP+ VDC+++RPTEK IF  FM+  S V + L I EL Y+    V    
Sbjct: 182 SAVYTCKR-DPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGV---- 236

Query: 219 HKDKPRGGCSPSSSASRA 236
            KD+ +G   P  + S A
Sbjct: 237 -KDRVKGKSDPYHATSGA 253


>gi|22779877 connexin 46 [Homo sapiens]
          Length = 435

 Score =  186 bits (471), Expect = 2e-47
 Identities = 99/234 (42%), Positives = 142/234 (60%), Gaps = 19/234 (8%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L  LL    ++ST  G++WL+V+F+FR+LV   AAE VWGDEQ DF CNT+QPGC 
Sbjct: 3   DWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCE 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAY-------REERERRHRQKHGDQCA 114
           NVCYD  FPIS+IR WALQ+IFV+ P+L+ + HV +       ++ERE   + K      
Sbjct: 63  NVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESPSP 122

Query: 115 K--LYDNAGKKH--------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQC 164
           K    DN   +         G L  TY+F++IFK + E  F+   + L +GF +  L +C
Sbjct: 123 KEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFL-YGFELKPLYRC 181

Query: 165 ANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218
            +  PCPN VDC+I+RPTEK IF  FM+  +   ++L + E+ +L   ++ +G+
Sbjct: 182 -DRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV 234


>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
          Length = 543

 Score =  179 bits (455), Expect = 2e-45
 Identities = 107/298 (35%), Positives = 159/298 (53%), Gaps = 36/298 (12%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L  +L  V+ +ST  G+IWL+++F+FR+LV  VAAE VW DEQ  F CNT+QPGC 
Sbjct: 3   DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYRE---ERERRHRQKHG-------- 110
           N+CYD+ FPIS IR W LQ+IFV+ PSL+ + H  YR    E++R+ ++ H         
Sbjct: 63  NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122

Query: 111 ---------DQCAKLYDNAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156
                    D+  +  +   + H     G L  TY+  ++ + ++E  F+   + L+ GF
Sbjct: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181

Query: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
            M  L +C    PCPN VDC+++RPTEK IF  FM   +A+ ++L I E+ +L   +++R
Sbjct: 182 QMHPLYKCTQ-PPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240

Query: 217 GLHKDKPRGGCSPSSSA-------SRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNL 267
            L+K     G    +         S A  C     L E   + P   NN+ Q    N+
Sbjct: 241 TLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPE--RISPLQANNQQQVIRVNV 296


>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
          Length = 515

 Score =  173 bits (439), Expect = 1e-43
 Identities = 98/242 (40%), Positives = 137/242 (56%), Gaps = 27/242 (11%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L   L  V+ +ST  G+IWL+++F+FR+LV  VAAE VW DEQ  F CNT+QPGC 
Sbjct: 3   DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYR----EE----------------- 100
           NVCYD  FPIS IR W LQ+IFV+ PSL+ + H  YR    EE                 
Sbjct: 63  NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122

Query: 101 ----RERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156
               R+RR  ++   Q  K   N     G L  TY+  +  + ++E  F+ +   L +GF
Sbjct: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFM-IGQYLLYGF 181

Query: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
           ++  L +C +  PCPNI+DC+++RPTEK IF  FM   + + + L I E+ +L   ++ R
Sbjct: 182 HLEPLFKC-HGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240

Query: 217 GL 218
           GL
Sbjct: 241 GL 242


>gi|32483412 connexin 40 [Homo sapiens]
          Length = 358

 Score =  161 bits (408), Expect = 5e-40
 Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L   L  V+K+ST  G++WL+V+F+FR+LV   AAE  WGDEQ DF C+T QPGC 
Sbjct: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121
           NVCYD  FPIS+IR W LQ+IFV+ PSL+ + H  +    + + + +  ++  ++  +  
Sbjct: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122

Query: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160
            ++                     G L  TY+ S++ +  +E  F+   + + +G  +  
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181

Query: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
           L  C   +PCP+ V+CY++RPTEK +F  FM+  +A+ ++L++ EL +L
Sbjct: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229


>gi|6631083 connexin 40 [Homo sapiens]
          Length = 358

 Score =  161 bits (408), Expect = 5e-40
 Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           DW  L   L  V+K+ST  G++WL+V+F+FR+LV   AAE  WGDEQ DF C+T QPGC 
Sbjct: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121
           NVCYD  FPIS+IR W LQ+IFV+ PSL+ + H  +    + + + +  ++  ++  +  
Sbjct: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122

Query: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160
            ++                     G L  TY+ S++ +  +E  F+   + + +G  +  
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181

Query: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
           L  C   +PCP+ V+CY++RPTEK +F  FM+  +A+ ++L++ EL +L
Sbjct: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229


>gi|122939172 connexin 45 [Homo sapiens]
          Length = 396

 Score =  138 bits (347), Expect = 6e-33
 Identities = 78/255 (30%), Positives = 128/255 (50%), Gaps = 48/255 (18%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M W  L  LL  ++ +ST  G+IWL+V+ VFR+++  V  E ++ DEQ  F CNT+QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVI---LH---------------------VA 96
            NVCYD + P+S++R W  Q+I V  PS++ +   +H                     + 
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 97  YREERERRHRQKHGDQCAKLY-------DNAGK---------------KHGGLWWTYLFS 134
           +++ R     ++  ++   +Y       D   K               +  GL   Y+  
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 135 LIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGA 194
           L+ + + E  FL   + L +GF +     C+ + PCP+ +DC+I+RPTEK IF   M G 
Sbjct: 181 LLARTVFEVGFLIGQYFL-YGFQVHPFYVCSRL-PCPHKIDCFISRPTEKTIFLLIMYGV 238

Query: 195 SAVCIVLTICELCYL 209
           + +C++L I E+ +L
Sbjct: 239 TGLCLLLNIWEMLHL 253


>gi|69122473 connexin 45 [Homo sapiens]
          Length = 396

 Score =  138 bits (347), Expect = 6e-33
 Identities = 78/255 (30%), Positives = 128/255 (50%), Gaps = 48/255 (18%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M W  L  LL  ++ +ST  G+IWL+V+ VFR+++  V  E ++ DEQ  F CNT+QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVI---LH---------------------VA 96
            NVCYD + P+S++R W  Q+I V  PS++ +   +H                     + 
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 97  YREERERRHRQKHGDQCAKLY-------DNAGK---------------KHGGLWWTYLFS 134
           +++ R     ++  ++   +Y       D   K               +  GL   Y+  
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 135 LIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGA 194
           L+ + + E  FL   + L +GF +     C+ + PCP+ +DC+I+RPTEK IF   M G 
Sbjct: 181 LLARTVFEVGFLIGQYFL-YGFQVHPFYVCSRL-PCPHKIDCFISRPTEKTIFLLIMYGV 238

Query: 195 SAVCIVLTICELCYL 209
           + +C++L I E+ +L
Sbjct: 239 TGLCLLLNIWEMLHL 253


>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
          Length = 294

 Score =  135 bits (340), Expect = 4e-32
 Identities = 84/262 (32%), Positives = 127/262 (48%), Gaps = 31/262 (11%)

Query: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
           +W  L +LL  V   S   GR+WL V+ +FR+LV       V+ DEQ++F CNT QPGC 
Sbjct: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62

Query: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD--------QC 113
             CYD  FP+S+ R W   ++ ++ P +L +++  +R  +E    +            QC
Sbjct: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQC 122

Query: 114 AKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173
           A     A +        YL S+  +L+ E  FL     L +GF +     CA   PCP+ 
Sbjct: 123 APCALRARRARR----CYLLSVALRLLAELTFLG-GQALLYGFRVAPHFACAG-PPCPHT 176

Query: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSA 233
           VDC+++RPTEK +F  F      +  +L++ EL +L        L K +PR G       
Sbjct: 177 VDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL--------LWKGRPRAG------- 221

Query: 234 SRASTCRCHHKLVEAGEVDPDP 255
            R + C   H+  EA ++ P P
Sbjct: 222 ERDNRCNRAHE--EAQKLLPPP 241


>gi|145699105 connexin40.1 [Homo sapiens]
          Length = 370

 Score =  122 bits (305), Expect = 4e-28
 Identities = 82/271 (30%), Positives = 129/271 (47%), Gaps = 29/271 (10%)

Query: 9   LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68
           L+  +N   T  G++W  +  + R+LV V+A   V+ DEQ+ F CNT QPGC NVCYD +
Sbjct: 10  LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69

Query: 69  FPISNIRLWALQLIFVTCPSLLVILHVAYR-------------EERERRHRQKHGDQCAK 115
            P+S++R W +Q + V  PS +  ++V +R             + RE    Q+   +C +
Sbjct: 70  SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQR---RCPR 126

Query: 116 LY-DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIV 174
            + +  G +       Y+  L+ + ++E  F   LH    GF  P+   C    PC  +V
Sbjct: 127 PFGERGGLQVPDFSAGYIIHLLLRTLLEAAF-GALHYFLFGFLAPKKFPCTR-PPCTGVV 184

Query: 175 DCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSAS 234
           DCY++RPTEK +   F+   SA+  +L + +L   +  R+ R       R G   S S  
Sbjct: 185 DCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRR-------RPGPPTSPSIR 237

Query: 235 RASTCRCHHKLVEAGEVDPDPGNNKLQASAP 265
           + S    H    E    D + G  +  A AP
Sbjct: 238 KQSGASGH---AEGRRTDEEGGREEEGAPAP 265


>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
          Length = 279

 Score =  118 bits (295), Expect = 6e-27
 Identities = 72/212 (33%), Positives = 110/212 (51%), Gaps = 12/212 (5%)

Query: 6   LQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCY 65
           L+ LL+  ++ ST  GR+ L V+  FR+++   +   V+GDEQ +F C+T+QPGC   C+
Sbjct: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65

Query: 66  DNYFPISNIRLWALQLIFVTCPSLL----VILHVAYREERERRHRQK----HGDQCAKLY 117
           D + P+S +R W  Q+I V  PS L     + HV +  E   + +++     G +     
Sbjct: 66  DAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTDV 125

Query: 118 DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCY 177
             AG     L W Y+  L  +L++E   L L + L +GF MP    C    PC   + C 
Sbjct: 126 PGAGSLR--LLWAYVAQLGARLVLEGAALGLQYHL-YGFQMPSSFACRR-EPCLGSITCN 181

Query: 178 IARPTEKKIFTYFMVGASAVCIVLTICELCYL 209
           ++RP+EK IF   M G S  C++ T  EL  L
Sbjct: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213


>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
          Length = 439

 Score =  107 bits (268), Expect = 8e-24
 Identities = 46/120 (38%), Positives = 76/120 (63%), Gaps = 6/120 (5%)

Query: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           M W  L  LL  ++ +ST  G++WL+V+ VFR+++  V  E ++ DEQ  F CNT+QPGC
Sbjct: 4   MSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGC 63

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYR------EERERRHRQKHGDQCA 114
            NVCYD + P+S++R W  Q++ ++ PS++ + +  +R      +ER R  R++ G + A
Sbjct: 64  DNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRA 123



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 7/108 (6%)

Query: 126 GLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKK 185
           GL   Y+  L+ +   E  FL   + L+ GF +     C+   PCP++VDC+++RPTEK 
Sbjct: 208 GLMRVYVAQLVARAAFEVAFLVGQYLLY-GFEVRPFFPCSR-QPCPHVVDCFVSRPTEKT 265

Query: 186 IFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSA 233
           +F   M   S +C++L +CE+ +L       G  +D  RG   P +SA
Sbjct: 266 VFLLVMYVVSCLCLLLNLCEMAHLGL-----GSAQDAVRGRRGPPASA 308


>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
          Length = 321

 Score =  102 bits (254), Expect = 4e-22
 Identities = 48/106 (45%), Positives = 66/106 (62%), Gaps = 1/106 (0%)

Query: 2   DWKTLQALL-SGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
           +W  L+ LL + V ++ST  GRI L+VV +FR+L+  +  E V+ DEQ  F CNT QPGC
Sbjct: 3   EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62

Query: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHR 106
              CYD  FPIS+IR W  Q+I V  PSL  I +  ++  ++R  R
Sbjct: 63  NQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 33/88 (37%), Positives = 54/88 (61%), Gaps = 2/88 (2%)

Query: 122 KKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARP 181
           ++  G+   Y+  ++F+  +E  FL   + L+ GF++P L +C N  PC   V+CY++RP
Sbjct: 190 RRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYEC-NRYPCIKEVECYVSRP 247

Query: 182 TEKKIFTYFMVGASAVCIVLTICELCYL 209
           TEK +F  FM   S +C+VL + EL +L
Sbjct: 248 TEKTVFLVFMFAVSGICVVLNLAELNHL 275


>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 12/137 (8%)

Query: 9   LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68
           LL+  + +ST  GR+   V+  FR+++   +   V+GDEQ +F C+T+QPGC   C+D +
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 69  FPISNIRLWALQLIFVTCPSLLVILHV-------AYRE-----ERERRHRQKHGDQCAKL 116
            P+S +R W  Q+I V  PS+L + +         YRE       E   R       A L
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRCGPSEVLERAPRPPAPATL 147

Query: 117 YDNAGKKHGGLWWTYLF 133
               G+  GGL  + LF
Sbjct: 148 PAFVGRSDGGLRLSVLF 164


>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 12/137 (8%)

Query: 9   LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68
           LL+  + +ST  GR+   V+  FR+++   +   V+GDEQ +F C+T+QPGC   C+D +
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 69  FPISNIRLWALQLIFVTCPSLLVILHV-------AYRE-----ERERRHRQKHGDQCAKL 116
            P+S +R W  Q+I V  PS+L + +         YRE       E   R       A L
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRCGPSEVLERAPRPPAPATL 147

Query: 117 YDNAGKKHGGLWWTYLF 133
               G+  GGL  + LF
Sbjct: 148 PAFVGRSDGGLRLSVLF 164


>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 12/137 (8%)

Query: 9   LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68
           LL+  + +ST  GR+   V+  FR+++   +   V+GDEQ +F C+T+QPGC   C+D +
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 69  FPISNIRLWALQLIFVTCPSLLVILHV-------AYRE-----ERERRHRQKHGDQCAKL 116
            P+S +R W  Q+I V  PS+L + +         YRE       E   R       A L
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRCGPSEVLERAPRPPAPATL 147

Query: 117 YDNAGKKHGGLWWTYLF 133
               G+  GGL  + LF
Sbjct: 148 PAFVGRSDGGLRLSVLF 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.474 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,305,946
Number of Sequences: 37866
Number of extensions: 504821
Number of successful extensions: 1655
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1585
Number of HSP's gapped (non-prelim): 42
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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