BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|54607056 connexin 31 [Homo sapiens] (270 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|54607056 connexin 31 [Homo sapiens] 575 e-164 gi|13128960 connexin 31 [Homo sapiens] 575 e-164 gi|23397464 gap junction protein, beta 4 [Homo sapiens] 319 1e-87 gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 310 9e-85 gi|42558283 gap junction protein beta 2 [Homo sapiens] 260 8e-70 gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 257 9e-69 gi|159032020 gap junction protein, beta 6 [Homo sapiens] 255 3e-68 gi|158966714 gap junction protein, beta 6 [Homo sapiens] 255 3e-68 gi|158966717 gap junction protein, beta 6 [Homo sapiens] 255 3e-68 gi|40254837 gap junction protein, beta 6 [Homo sapiens] 255 3e-68 gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 249 1e-66 gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 249 1e-66 gi|62865885 connexin 37 [Homo sapiens] 199 2e-51 gi|55953076 connexin 50 [Homo sapiens] 190 1e-48 gi|4504001 connexin 43 [Homo sapiens] 189 3e-48 gi|22779877 connexin 46 [Homo sapiens] 186 2e-47 gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 179 2e-45 gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 173 1e-43 gi|32483412 connexin 40 [Homo sapiens] 161 5e-40 gi|6631083 connexin 40 [Homo sapiens] 161 5e-40 gi|122939172 connexin 45 [Homo sapiens] 138 6e-33 gi|69122473 connexin 45 [Homo sapiens] 138 6e-33 gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 135 4e-32 gi|145699105 connexin40.1 [Homo sapiens] 122 4e-28 gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 118 6e-27 gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 107 8e-24 gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 102 4e-22 gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 76 4e-14 gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 76 4e-14 gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 76 4e-14 >gi|54607056 connexin 31 [Homo sapiens] Length = 270 Score = 575 bits (1482), Expect = e-164 Identities = 270/270 (100%), Positives = 270/270 (100%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC Sbjct: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180 Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240 Query: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI Sbjct: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270 >gi|13128960 connexin 31 [Homo sapiens] Length = 270 Score = 575 bits (1482), Expect = e-164 Identities = 270/270 (100%), Positives = 270/270 (100%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC Sbjct: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180 Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240 Query: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI Sbjct: 241 CHHKLVEAGEVDPDPGNNKLQASAPNLTPI 270 >gi|23397464 gap junction protein, beta 4 [Homo sapiens] Length = 266 Score = 319 bits (818), Expect = 1e-87 Identities = 154/264 (58%), Positives = 187/264 (70%), Gaps = 9/264 (3%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M+W LQ LLSGVNKYST RIWLSVVF+FRVLVYVVAAE VW DEQKDF CNTKQPGC Sbjct: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 NVCYD +FP+S++RLWALQLI VTCPSLLV++HVAYREERER+H KHG LYDN Sbjct: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120 Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180 KK GGLWWTYL SLIFK ++ FLY+ H L+ ++MPR+V C +V PCP+ VDCYI+R Sbjct: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVAC-SVEPCPHTVDCYISR 179 Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLI---CHRVLRGLHKDKPRGGCSPSSSASRAS 237 PTEKK+FTYFMV +A+CI+L + E+ YL+ C + H+ C P + Sbjct: 180 PTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLPDTCPPYVL 239 Query: 238 TCRCHHK-----LVEAGEVDPDPG 256 + H + L++AG D G Sbjct: 240 SQGGHPEDGNSVLMKAGSAPVDAG 263 >gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] Length = 273 Score = 310 bits (794), Expect = 9e-85 Identities = 137/240 (57%), Positives = 182/240 (75%), Gaps = 1/240 (0%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M+W + LLSGVNKYSTAFGRIWLS+VF+FRVLVY+V AERVW D+ KDFDCNT+QPGC Sbjct: 1 MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 +NVC+D +FP+S++RLWALQLI VTCPSLLV++HVAYRE +E+RHR+ HG+ +LY N Sbjct: 61 SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120 Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180 GKK GGLWWTY+ SL+FK ++ FLY+ H+ + + +P +V+C + PCPNIVDC+I++ Sbjct: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKC-HADPCPNIVDCFISK 179 Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240 P+EK IFT FMV +A+CI+L + EL YL+ R L K + C+ S+C+ Sbjct: 180 PSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTTSSCK 239 >gi|42558283 gap junction protein beta 2 [Homo sapiens] Length = 226 Score = 260 bits (665), Expect = 8e-70 Identities = 120/216 (55%), Positives = 160/216 (74%), Gaps = 8/216 (3%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 MDW TLQ +L GVNK+ST+ G+IWL+V+F+FR+++ VVAA+ VWGDEQ DF CNT QPGC Sbjct: 1 MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 NVCYD+YFPIS+IRLWALQLIFV+ P+LLV +HVAYR ++R K G+ ++ D Sbjct: 61 KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIK-GEIKSEFKDIE 119 Query: 121 GKK------HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIV 174 K G LWWTY S+ F++I E F+Y+ + ++ GF+M RLV+C N PCPN V Sbjct: 120 EIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKC-NAWPCPNTV 178 Query: 175 DCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210 DC+++RPTEK +FT FM+ S +CI+L + ELCYL+ Sbjct: 179 DCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLL 214 >gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] Length = 223 Score = 257 bits (656), Expect = 9e-69 Identities = 124/210 (59%), Positives = 157/210 (74%), Gaps = 8/210 (3%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M W L+ LLSGVNKYST G IWL+VVFVFR+LVY+VAAE VW DEQK+F+CN++QPGC Sbjct: 1 MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120 NVC+D++FPIS +RLWALQLI V+ PSLLV+LHVAY E RE+RHR+ KLY + Sbjct: 61 KNVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRK-------KLYVSP 113 Query: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180 G GGLW+ YL SLI K E FL L + L+ GF++P L++C ++ PCPN VDC+I++ Sbjct: 114 GTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKC-DLKPCPNTVDCFISK 172 Query: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLI 210 PTEK IF F+V S +CIVL EL +L+ Sbjct: 173 PTEKTIFILFLVITSCLCIVLNFIELSFLV 202 >gi|159032020 gap junction protein, beta 6 [Homo sapiens] Length = 261 Score = 255 bits (651), Expect = 3e-68 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 MDW TL + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119 NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E R+ R+ K ++ Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120 Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175 K+ G LWWTY S+ F++I E F+Y+ + L++G+++P +++C + PCPN+VD Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179 Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210 C+I+RPTEK +FT FM+ AS +C++L + ELCYL+ Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214 >gi|158966714 gap junction protein, beta 6 [Homo sapiens] Length = 261 Score = 255 bits (651), Expect = 3e-68 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 MDW TL + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119 NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E R+ R+ K ++ Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120 Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175 K+ G LWWTY S+ F++I E F+Y+ + L++G+++P +++C + PCPN+VD Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179 Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210 C+I+RPTEK +FT FM+ AS +C++L + ELCYL+ Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214 >gi|158966717 gap junction protein, beta 6 [Homo sapiens] Length = 261 Score = 255 bits (651), Expect = 3e-68 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 MDW TL + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119 NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E R+ R+ K ++ Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120 Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175 K+ G LWWTY S+ F++I E F+Y+ + L++G+++P +++C + PCPN+VD Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179 Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210 C+I+RPTEK +FT FM+ AS +C++L + ELCYL+ Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214 >gi|40254837 gap junction protein, beta 6 [Homo sapiens] Length = 261 Score = 255 bits (651), Expect = 3e-68 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 MDW TL + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119 NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E R+ R+ K ++ Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120 Query: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175 K+ G LWWTY S+ F++I E F+Y+ + L++G+++P +++C + PCPN+VD Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179 Query: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210 C+I+RPTEK +FT FM+ AS +C++L + ELCYL+ Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214 >gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] Length = 283 Score = 249 bits (637), Expect = 1e-66 Identities = 116/223 (52%), Positives = 163/223 (73%), Gaps = 11/223 (4%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M+W L LLSGVN++STA GR+WLSV+F+FR++V VVAAE VWGDE+ F CNT QPGC Sbjct: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERR--HRQKHGDQCAKLYD 118 +VCYD +FPIS++RLW+LQLI V+ P+LLV +HVA+++ E++ + HGD L+ Sbjct: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117 Query: 119 NAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173 K+H G LWWTY+ S++F+L+ E +F+Y+ + L+ G+ M RLV+C +V PCPN Sbjct: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKC-DVYPCPNT 176 Query: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216 VDC+++RPTEK +FT FM+ AS +CI+L + E+ YLI R Sbjct: 177 VDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR 219 >gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] Length = 283 Score = 249 bits (637), Expect = 1e-66 Identities = 116/223 (52%), Positives = 163/223 (73%), Gaps = 11/223 (4%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M+W L LLSGVN++STA GR+WLSV+F+FR++V VVAAE VWGDE+ F CNT QPGC Sbjct: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERR--HRQKHGDQCAKLYD 118 +VCYD +FPIS++RLW+LQLI V+ P+LLV +HVA+++ E++ + HGD L+ Sbjct: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117 Query: 119 NAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173 K+H G LWWTY+ S++F+L+ E +F+Y+ + L+ G+ M RLV+C +V PCPN Sbjct: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKC-DVYPCPNT 176 Query: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216 VDC+++RPTEK +FT FM+ AS +CI+L + E+ YLI R Sbjct: 177 VDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR 219 >gi|62865885 connexin 37 [Homo sapiens] Length = 333 Score = 199 bits (507), Expect = 2e-51 Identities = 105/240 (43%), Positives = 145/240 (60%), Gaps = 25/240 (10%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L+ LL V ++ST G+IWL+V+F+FR+L+ +A E VWGDEQ DF+CNT QPGCT Sbjct: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD---------- 111 NVCYD FPIS+IR W LQ +FV+ P+L+ + HV Y RE R RQK G+ Sbjct: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122 Query: 112 ----------QCAKL---YDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNM 158 Q AK+ D + G L TY+ S++ K ++E FLY L +G+ M Sbjct: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRL-YGWTM 181 Query: 159 PRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218 + C APCP +VDC+++RPTEK IF FM+ + +VL + EL +L+C + RG+ Sbjct: 182 EPVFVCQR-APCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGM 240 >gi|55953076 connexin 50 [Homo sapiens] Length = 433 Score = 190 bits (482), Expect = 1e-48 Identities = 100/227 (44%), Positives = 141/227 (62%), Gaps = 21/227 (9%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L +L VN++ST GR+WL+V+F+FR+L+ AAE VWGDEQ DF CNT+QPGC Sbjct: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILH----VAYREERERRHRQKHGDQC---- 113 NVCYD FPIS+IRLW LQ+IFV+ PSL+ + H V E+R+ R ++ G Q Sbjct: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122 Query: 114 ----AKLYDNAGKK-------HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLV 162 + ++G K G L TY+ +IFK + E F+ + H +GF + L Sbjct: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFI-VGHYFLYGFRILPLY 181 Query: 163 QCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209 +C+ PCPN+VDC+++RPTEK IF FM+ ++V + L + EL +L Sbjct: 182 RCSR-WPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227 >gi|4504001 connexin 43 [Homo sapiens] Length = 382 Score = 189 bits (479), Expect = 3e-48 Identities = 105/258 (40%), Positives = 140/258 (54%), Gaps = 30/258 (11%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L LL V YSTA G++WLSV+F+FR+L+ A E WGDEQ F CNT+QPGC Sbjct: 3 DWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCE 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121 NVCYD FPIS++R W LQ+IFV+ P+LL + HV Y +E + +K + D Sbjct: 63 NVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVN 122 Query: 122 -----------------------KKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNM 158 K GGL TY+ S++FK I E FL L+ +GF++ Sbjct: 123 VDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFL-LIQWYIYGFSL 181 Query: 159 PRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218 + C PCP+ VDC+++RPTEK IF FM+ S V + L I EL Y+ V Sbjct: 182 SAVYTCKR-DPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGV---- 236 Query: 219 HKDKPRGGCSPSSSASRA 236 KD+ +G P + S A Sbjct: 237 -KDRVKGKSDPYHATSGA 253 >gi|22779877 connexin 46 [Homo sapiens] Length = 435 Score = 186 bits (471), Expect = 2e-47 Identities = 99/234 (42%), Positives = 142/234 (60%), Gaps = 19/234 (8%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L LL ++ST G++WL+V+F+FR+LV AAE VWGDEQ DF CNT+QPGC Sbjct: 3 DWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCE 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAY-------REERERRHRQKHGDQCA 114 NVCYD FPIS+IR WALQ+IFV+ P+L+ + HV + ++ERE + K Sbjct: 63 NVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESPSP 122 Query: 115 K--LYDNAGKKH--------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQC 164 K DN + G L TY+F++IFK + E F+ + L +GF + L +C Sbjct: 123 KEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFL-YGFELKPLYRC 181 Query: 165 ANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL 218 + PCPN VDC+I+RPTEK IF FM+ + ++L + E+ +L ++ +G+ Sbjct: 182 -DRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGV 234 >gi|14211941 gap junction protein, alpha 10 [Homo sapiens] Length = 543 Score = 179 bits (455), Expect = 2e-45 Identities = 107/298 (35%), Positives = 159/298 (53%), Gaps = 36/298 (12%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L +L V+ +ST G+IWL+++F+FR+LV VAAE VW DEQ F CNT+QPGC Sbjct: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYRE---ERERRHRQKHG-------- 110 N+CYD+ FPIS IR W LQ+IFV+ PSL+ + H YR E++R+ ++ H Sbjct: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122 Query: 111 ---------DQCAKLYDNAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156 D+ + + + H G L TY+ ++ + ++E F+ + L+ GF Sbjct: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181 Query: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216 M L +C PCPN VDC+++RPTEK IF FM +A+ ++L I E+ +L +++R Sbjct: 182 QMHPLYKCTQ-PPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240 Query: 217 GLHKDKPRGGCSPSSSA-------SRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNL 267 L+K G + S A C L E + P NN+ Q N+ Sbjct: 241 TLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPE--RISPLQANNQQQVIRVNV 296 >gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] Length = 515 Score = 173 bits (439), Expect = 1e-43 Identities = 98/242 (40%), Positives = 137/242 (56%), Gaps = 27/242 (11%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L L V+ +ST G+IWL+++F+FR+LV VAAE VW DEQ F CNT+QPGC Sbjct: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYR----EE----------------- 100 NVCYD FPIS IR W LQ+IFV+ PSL+ + H YR EE Sbjct: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122 Query: 101 ----RERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156 R+RR ++ Q K N G L TY+ + + ++E F+ + L +GF Sbjct: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFM-IGQYLLYGF 181 Query: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216 ++ L +C + PCPNI+DC+++RPTEK IF FM + + + L I E+ +L ++ R Sbjct: 182 HLEPLFKC-HGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240 Query: 217 GL 218 GL Sbjct: 241 GL 242 >gi|32483412 connexin 40 [Homo sapiens] Length = 358 Score = 161 bits (408), Expect = 5e-40 Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L L V+K+ST G++WL+V+F+FR+LV AAE WGDEQ DF C+T QPGC Sbjct: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121 NVCYD FPIS+IR W LQ+IFV+ PSL+ + H + + + + + ++ ++ + Sbjct: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122 Query: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160 ++ G L TY+ S++ + +E F+ + + +G + Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181 Query: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209 L C +PCP+ V+CY++RPTEK +F FM+ +A+ ++L++ EL +L Sbjct: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229 >gi|6631083 connexin 40 [Homo sapiens] Length = 358 Score = 161 bits (408), Expect = 5e-40 Identities = 83/229 (36%), Positives = 133/229 (58%), Gaps = 23/229 (10%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 DW L L V+K+ST G++WL+V+F+FR+LV AAE WGDEQ DF C+T QPGC Sbjct: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAG 121 NVCYD FPIS+IR W LQ+IFV+ PSL+ + H + + + + + ++ ++ + Sbjct: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122 Query: 122 KKH---------------------GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR 160 ++ G L TY+ S++ + +E F+ + + +G + Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFI-YGIFLTT 181 Query: 161 LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYL 209 L C +PCP+ V+CY++RPTEK +F FM+ +A+ ++L++ EL +L Sbjct: 182 LHVCRR-SPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229 >gi|122939172 connexin 45 [Homo sapiens] Length = 396 Score = 138 bits (347), Expect = 6e-33 Identities = 78/255 (30%), Positives = 128/255 (50%), Gaps = 48/255 (18%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M W L LL ++ +ST G+IWL+V+ VFR+++ V E ++ DEQ F CNT+QPGC Sbjct: 1 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVI---LH---------------------VA 96 NVCYD + P+S++R W Q+I V PS++ + +H + Sbjct: 61 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120 Query: 97 YREERERRHRQKHGDQCAKLY-------DNAGK---------------KHGGLWWTYLFS 134 +++ R ++ ++ +Y D K + GL Y+ Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180 Query: 135 LIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGA 194 L+ + + E FL + L +GF + C+ + PCP+ +DC+I+RPTEK IF M G Sbjct: 181 LLARTVFEVGFLIGQYFL-YGFQVHPFYVCSRL-PCPHKIDCFISRPTEKTIFLLIMYGV 238 Query: 195 SAVCIVLTICELCYL 209 + +C++L I E+ +L Sbjct: 239 TGLCLLLNIWEMLHL 253 >gi|69122473 connexin 45 [Homo sapiens] Length = 396 Score = 138 bits (347), Expect = 6e-33 Identities = 78/255 (30%), Positives = 128/255 (50%), Gaps = 48/255 (18%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M W L LL ++ +ST G+IWL+V+ VFR+++ V E ++ DEQ F CNT+QPGC Sbjct: 1 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVI---LH---------------------VA 96 NVCYD + P+S++R W Q+I V PS++ + +H + Sbjct: 61 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120 Query: 97 YREERERRHRQKHGDQCAKLY-------DNAGK---------------KHGGLWWTYLFS 134 +++ R ++ ++ +Y D K + GL Y+ Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180 Query: 135 LIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGA 194 L+ + + E FL + L +GF + C+ + PCP+ +DC+I+RPTEK IF M G Sbjct: 181 LLARTVFEVGFLIGQYFL-YGFQVHPFYVCSRL-PCPHKIDCFISRPTEKTIFLLIMYGV 238 Query: 195 SAVCIVLTICELCYL 209 + +C++L I E+ +L Sbjct: 239 TGLCLLLNIWEMLHL 253 >gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] Length = 294 Score = 135 bits (340), Expect = 4e-32 Identities = 84/262 (32%), Positives = 127/262 (48%), Gaps = 31/262 (11%) Query: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61 +W L +LL V S GR+WL V+ +FR+LV V+ DEQ++F CNT QPGC Sbjct: 3 EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62 Query: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD--------QC 113 CYD FP+S+ R W ++ ++ P +L +++ +R +E + QC Sbjct: 63 QTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQC 122 Query: 114 AKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173 A A + YL S+ +L+ E FL L +GF + CA PCP+ Sbjct: 123 APCALRARRARR----CYLLSVALRLLAELTFLG-GQALLYGFRVAPHFACAG-PPCPHT 176 Query: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSA 233 VDC+++RPTEK +F F + +L++ EL +L L K +PR G Sbjct: 177 VDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL--------LWKGRPRAG------- 221 Query: 234 SRASTCRCHHKLVEAGEVDPDP 255 R + C H+ EA ++ P P Sbjct: 222 ERDNRCNRAHE--EAQKLLPPP 241 >gi|145699105 connexin40.1 [Homo sapiens] Length = 370 Score = 122 bits (305), Expect = 4e-28 Identities = 82/271 (30%), Positives = 129/271 (47%), Gaps = 29/271 (10%) Query: 9 LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68 L+ +N T G++W + + R+LV V+A V+ DEQ+ F CNT QPGC NVCYD + Sbjct: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69 Query: 69 FPISNIRLWALQLIFVTCPSLLVILHVAYR-------------EERERRHRQKHGDQCAK 115 P+S++R W +Q + V PS + ++V +R + RE Q+ +C + Sbjct: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQR---RCPR 126 Query: 116 LY-DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIV 174 + + G + Y+ L+ + ++E F LH GF P+ C PC +V Sbjct: 127 PFGERGGLQVPDFSAGYIIHLLLRTLLEAAF-GALHYFLFGFLAPKKFPCTR-PPCTGVV 184 Query: 175 DCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSAS 234 DCY++RPTEK + F+ SA+ +L + +L + R+ R R G S S Sbjct: 185 DCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRR-------RPGPPTSPSIR 237 Query: 235 RASTCRCHHKLVEAGEVDPDPGNNKLQASAP 265 + S H E D + G + A AP Sbjct: 238 KQSGASGH---AEGRRTDEEGGREEEGAPAP 265 >gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] Length = 279 Score = 118 bits (295), Expect = 6e-27 Identities = 72/212 (33%), Positives = 110/212 (51%), Gaps = 12/212 (5%) Query: 6 LQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCY 65 L+ LL+ ++ ST GR+ L V+ FR+++ + V+GDEQ +F C+T+QPGC C+ Sbjct: 6 LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65 Query: 66 DNYFPISNIRLWALQLIFVTCPSLL----VILHVAYREERERRHRQK----HGDQCAKLY 117 D + P+S +R W Q+I V PS L + HV + E + +++ G + Sbjct: 66 DAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTDV 125 Query: 118 DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCY 177 AG L W Y+ L +L++E L L + L +GF MP C PC + C Sbjct: 126 PGAGSLR--LLWAYVAQLGARLVLEGAALGLQYHL-YGFQMPSSFACRR-EPCLGSITCN 181 Query: 178 IARPTEKKIFTYFMVGASAVCIVLTICELCYL 209 ++RP+EK IF M G S C++ T EL L Sbjct: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213 >gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] Length = 439 Score = 107 bits (268), Expect = 8e-24 Identities = 46/120 (38%), Positives = 76/120 (63%), Gaps = 6/120 (5%) Query: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 M W L LL ++ +ST G++WL+V+ VFR+++ V E ++ DEQ F CNT+QPGC Sbjct: 4 MSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGC 63 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYR------EERERRHRQKHGDQCA 114 NVCYD + P+S++R W Q++ ++ PS++ + + +R +ER R R++ G + A Sbjct: 64 DNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRA 123 Score = 65.9 bits (159), Expect = 4e-11 Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 7/108 (6%) Query: 126 GLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKK 185 GL Y+ L+ + E FL + L+ GF + C+ PCP++VDC+++RPTEK Sbjct: 208 GLMRVYVAQLVARAAFEVAFLVGQYLLY-GFEVRPFFPCSR-QPCPHVVDCFVSRPTEKT 265 Query: 186 IFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSA 233 +F M S +C++L +CE+ +L G +D RG P +SA Sbjct: 266 VFLLVMYVVSCLCLLLNLCEMAHLGL-----GSAQDAVRGRRGPPASA 308 >gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] Length = 321 Score = 102 bits (254), Expect = 4e-22 Identities = 48/106 (45%), Positives = 66/106 (62%), Gaps = 1/106 (0%) Query: 2 DWKTLQALL-SGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60 +W L+ LL + V ++ST GRI L+VV +FR+L+ + E V+ DEQ F CNT QPGC Sbjct: 3 EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62 Query: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHR 106 CYD FPIS+IR W Q+I V PSL I + ++ ++R R Sbjct: 63 NQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108 Score = 66.6 bits (161), Expect = 2e-11 Identities = 33/88 (37%), Positives = 54/88 (61%), Gaps = 2/88 (2%) Query: 122 KKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARP 181 ++ G+ Y+ ++F+ +E FL + L+ GF++P L +C N PC V+CY++RP Sbjct: 190 RRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYEC-NRYPCIKEVECYVSRP 247 Query: 182 TEKKIFTYFMVGASAVCIVLTICELCYL 209 TEK +F FM S +C+VL + EL +L Sbjct: 248 TEKTVFLVFMFAVSGICVVLNLAELNHL 275 >gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] Length = 222 Score = 75.9 bits (185), Expect = 4e-14 Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 12/137 (8%) Query: 9 LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68 LL+ + +ST GR+ V+ FR+++ + V+GDEQ +F C+T+QPGC C+D + Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87 Query: 69 FPISNIRLWALQLIFVTCPSLLVILHV-------AYRE-----ERERRHRQKHGDQCAKL 116 P+S +R W Q+I V PS+L + + YRE E R A L Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRCGPSEVLERAPRPPAPATL 147 Query: 117 YDNAGKKHGGLWWTYLF 133 G+ GGL + LF Sbjct: 148 PAFVGRSDGGLRLSVLF 164 >gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] Length = 222 Score = 75.9 bits (185), Expect = 4e-14 Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 12/137 (8%) Query: 9 LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68 LL+ + +ST GR+ V+ FR+++ + V+GDEQ +F C+T+QPGC C+D + Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87 Query: 69 FPISNIRLWALQLIFVTCPSLLVILHV-------AYRE-----ERERRHRQKHGDQCAKL 116 P+S +R W Q+I V PS+L + + YRE E R A L Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRCGPSEVLERAPRPPAPATL 147 Query: 117 YDNAGKKHGGLWWTYLF 133 G+ GGL + LF Sbjct: 148 PAFVGRSDGGLRLSVLF 164 >gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] Length = 222 Score = 75.9 bits (185), Expect = 4e-14 Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 12/137 (8%) Query: 9 LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68 LL+ + +ST GR+ V+ FR+++ + V+GDEQ +F C+T+QPGC C+D + Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87 Query: 69 FPISNIRLWALQLIFVTCPSLLVILHV-------AYRE-----ERERRHRQKHGDQCAKL 116 P+S +R W Q+I V PS+L + + YRE E R A L Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRCGPSEVLERAPRPPAPATL 147 Query: 117 YDNAGKKHGGLWWTYLF 133 G+ GGL + LF Sbjct: 148 PAFVGRSDGGLRLSVLF 164 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.141 0.474 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,305,946 Number of Sequences: 37866 Number of extensions: 504821 Number of successful extensions: 1655 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 1585 Number of HSP's gapped (non-prelim): 42 length of query: 270 length of database: 18,247,518 effective HSP length: 101 effective length of query: 169 effective length of database: 14,423,052 effective search space: 2437495788 effective search space used: 2437495788 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.