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Search of human proteins with 5454114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5454114 tissue factor pathway inhibitor isoform a precursor
[Homo sapiens]
(304 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5454114 tissue factor pathway inhibitor isoform a precursor [... 649 0.0
gi|73760409 tissue factor pathway inhibitor isoform b precursor ... 447 e-126
gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens] 118 7e-27
gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ... 98 1e-20
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p... 98 1e-20
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi... 93 3e-19
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ... 92 6e-19
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap... 89 4e-18
gi|28212222 WFIKKN2 protein [Homo sapiens] 79 6e-15
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 69 5e-12
gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo sap... 68 1e-11
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap... 65 6e-11
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s... 65 6e-11
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 64 1e-10
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 64 1e-10
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 64 1e-10
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 62 8e-10
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 62 8e-10
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa... 61 1e-09
gi|145309328 papilin [Homo sapiens] 59 7e-09
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 58 1e-08
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 57 3e-08
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 56 5e-08
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 52 7e-07
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 51 1e-06
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 51 1e-06
gi|110626171 serine peptidase inhibitor, Kunitz type 4 [Homo sap... 49 4e-06
>gi|5454114 tissue factor pathway inhibitor isoform a precursor
[Homo sapiens]
Length = 304
Score = 649 bits (1674), Expect = 0.0
Identities = 304/304 (100%), Positives = 304/304 (100%)
Query: 1 MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADD 60
MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADD
Sbjct: 1 MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADD 60
Query: 61 GPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQE 120
GPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQE
Sbjct: 61 GPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQE 120
Query: 121 KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPN 180
KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPN
Sbjct: 121 KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPN 180
Query: 181 GFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIG 240
GFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIG
Sbjct: 181 GFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIG 240
Query: 241 KCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIF 300
KCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIF
Sbjct: 241 KCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIF 300
Query: 301 VKNM 304
VKNM
Sbjct: 301 VKNM 304
>gi|73760409 tissue factor pathway inhibitor isoform b precursor
[Homo sapiens]
Length = 251
Score = 447 bits (1151), Expect = e-126
Identities = 209/209 (100%), Positives = 209/209 (100%)
Query: 1 MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADD 60
MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADD
Sbjct: 1 MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADD 60
Query: 61 GPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQE 120
GPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQE
Sbjct: 61 GPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQE 120
Query: 121 KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPN 180
KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPN
Sbjct: 121 KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPN 180
Query: 181 GFQVDNYGTQLNAVNNSLTPQSTKVPSLF 209
GFQVDNYGTQLNAVNNSLTPQSTKVPSLF
Sbjct: 181 GFQVDNYGTQLNAVNNSLTPQSTKVPSLF 209
Score = 112 bits (281), Expect = 3e-25
Identities = 55/147 (37%), Positives = 77/147 (52%), Gaps = 21/147 (14%)
Query: 124 FCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQ 183
FC + D G C+ + R+F+N T+QCE F YGGC GN N FE+LEECK +C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC-------- 104
Query: 184 VDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCR 243
T+ NA + + + + P +C D G+CR R++YN+ +C
Sbjct: 105 -----TRDNA--------NRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCE 151
Query: 244 PFKYSGCGGNENNFTSKQECLRACKKG 270
FKY GC GN NNF + +EC C+ G
Sbjct: 152 RFKYGGCLGNMNNFETLEECKNICEDG 178
Score = 61.2 bits (147), Expect = 1e-09
Identities = 32/82 (39%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Query: 203 TKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQE 262
T++P L H S+C AD G C+A RF++N +C F Y GC GN+N F S +E
Sbjct: 42 TELPPLKLMH--SFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEE 99
Query: 263 CLRACKKGFIQRISKGGLIKTK 284
C + C + RI K L + K
Sbjct: 100 CKKMCTRDNANRIIKTTLQQEK 121
>gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
Length = 235
Score = 118 bits (295), Expect = 7e-27
Identities = 67/200 (33%), Positives = 91/200 (45%), Gaps = 42/200 (21%)
Query: 123 DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC------- 175
+ C L D G CR + RY+Y+ T+ C +F YGGC GN NNF T E C + C
Sbjct: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 93
Query: 176 ---------EDGPNGFQVDNY---------------GTQLNAVNNSLTPQSTKVPSLFEF 211
+D G + Y G N + N ++T +
Sbjct: 94 KVCRLQVSVDDQCEG-STEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPK 152
Query: 212 HGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGF 271
PS+C +P D GLC AN R+Y+N C F Y+GCGGN+NNF S+++C RAC K
Sbjct: 153 KIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKA- 211
Query: 272 IQRISKGGLIKTKRKRKKQR 291
+K K+K K R
Sbjct: 212 ---------LKKKKKMPKLR 222
Score = 60.5 bits (145), Expect = 2e-09
Identities = 26/59 (44%), Positives = 35/59 (59%)
Query: 48 KLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106
K + SFC D+G C A + R++FN R C+ F Y GC GN N F S E+CK+ C +
Sbjct: 152 KKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 97.8 bits (242), Expect = 1e-20
Identities = 62/195 (31%), Positives = 86/195 (44%), Gaps = 33/195 (16%)
Query: 107 DNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFE 166
D AN + ++ D+C G CRG R++Y+ + C+ F YGGCLGN NN+
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 167 TLEECKNICE--DGP---------------------NGFQVDNY---GTQLNAVNNSLTP 200
EEC C GP NG +D++ N + S
Sbjct: 292 REEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 351
Query: 201 QSTKVPSLFE----FHGPS---WCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGN 253
K S F+ H PS C+ D GLC+ + R+YYN C F Y GC GN
Sbjct: 352 ACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGN 411
Query: 254 ENNFTSKQECLRACK 268
+NNF +Q+CL +C+
Sbjct: 412 KNNFEEEQQCLESCR 426
Score = 67.8 bits (164), Expect = 1e-11
Identities = 48/204 (23%), Positives = 71/204 (34%), Gaps = 54/204 (26%)
Query: 26 LNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYG 85
L S + E T + K +C G C+ R++++ + C+ F+YG
Sbjct: 222 LTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYG 281
Query: 86 GCEGNQNRFESLEECKKMCT-----------------------RDNANRIIKTTLQQEKP 122
GC GN+N + EEC C R + I + L+ +
Sbjct: 282 GCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDT 341
Query: 123 DFCFLEEDPGICRGY-------------------------------ITRYFYNNQTKQCE 151
C D C Y I R++YN ++ C
Sbjct: 342 PNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCA 401
Query: 152 RFKYGGCLGNMNNFETLEECKNIC 175
RF YGGC GN NNFE ++C C
Sbjct: 402 RFTYGGCYGNKNNFEEEQQCLESC 425
>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 97.8 bits (242), Expect = 1e-20
Identities = 62/195 (31%), Positives = 86/195 (44%), Gaps = 33/195 (16%)
Query: 107 DNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFE 166
D AN + ++ D+C G CRG R++Y+ + C+ F YGGCLGN NN+
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 167 TLEECKNICE--DGP---------------------NGFQVDNY---GTQLNAVNNSLTP 200
EEC C GP NG +D++ N + S
Sbjct: 292 REEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 351
Query: 201 QSTKVPSLFE----FHGPS---WCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGN 253
K S F+ H PS C+ D GLC+ + R+YYN C F Y GC GN
Sbjct: 352 ACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGN 411
Query: 254 ENNFTSKQECLRACK 268
+NNF +Q+CL +C+
Sbjct: 412 KNNFEEEQQCLESCR 426
Score = 67.8 bits (164), Expect = 1e-11
Identities = 48/204 (23%), Positives = 71/204 (34%), Gaps = 54/204 (26%)
Query: 26 LNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYG 85
L S + E T + K +C G C+ R++++ + C+ F+YG
Sbjct: 222 LTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYG 281
Query: 86 GCEGNQNRFESLEECKKMCT-----------------------RDNANRIIKTTLQQEKP 122
GC GN+N + EEC C R + I + L+ +
Sbjct: 282 GCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDT 341
Query: 123 DFCFLEEDPGICRGY-------------------------------ITRYFYNNQTKQCE 151
C D C Y I R++YN ++ C
Sbjct: 342 PNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCA 401
Query: 152 RFKYGGCLGNMNNFETLEECKNIC 175
RF YGGC GN NNFE ++C C
Sbjct: 402 RFTYGGCYGNKNNFEEEQQCLESC 425
>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
sapiens]
Length = 252
Score = 92.8 bits (229), Expect = 3e-19
Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
Query: 123 DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGF 182
DFC + + G CR + R++YN C+ F YGGC GN NN+ T EEC C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 183 QVDNYGTQLNAVNNSLTP----QSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSV 238
D T NA ++S+ Q ++ S F+ +C A G CRA+ R+Y++
Sbjct: 96 TGD-LATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVE 154
Query: 239 IGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C F Y GC GN+N++ S++ C+ C
Sbjct: 155 RNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 86.7 bits (213), Expect = 2e-17
Identities = 45/150 (30%), Positives = 70/150 (46%), Gaps = 24/150 (16%)
Query: 50 MHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC--TRD 107
+H FC G C+A M R+++N+ C+ F+YGGC+GN N + + EEC K C +
Sbjct: 34 IHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTE 93
Query: 108 NANRIIKTT------------LQQEKPD----------FCFLEEDPGICRGYITRYFYNN 145
NA + T+ +Q+ D +C G CR R++++
Sbjct: 94 NATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDV 153
Query: 146 QTKQCERFKYGGCLGNMNNFETLEECKNIC 175
+ C F YGGC GN N++ + E C C
Sbjct: 154 ERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (145), Expect = 2e-09
Identities = 24/58 (41%), Positives = 32/58 (55%)
Query: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNAN 110
+C A GPC+A R++F++ C FIYGGC GN+N + S E C C R N
Sbjct: 132 YCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQEN 189
>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
precursor [Homo sapiens]
Length = 529
Score = 92.0 bits (227), Expect = 6e-19
Identities = 62/211 (29%), Positives = 87/211 (41%), Gaps = 49/211 (23%)
Query: 107 DNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFE 166
D AN + ++ D+C G CRG R++Y+ + C+ F YGGCLGN NN+
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 167 TLEECKNIC---EDGP------------------------------------NGFQVDNY 187
EEC C + GP NG +D++
Sbjct: 292 REEECILACRGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSF 351
Query: 188 ---GTQLNAVNNSLTPQSTKVPSLFE----FHGPS---WCLTPADRGLCRANENRFYYNS 237
N + S K S F+ H PS C+ D GLC+ + R+YYN
Sbjct: 352 LECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNP 411
Query: 238 VIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
C F Y GC GN+NNF +Q+CL +C+
Sbjct: 412 FSEHCARFTYGGCYGNKNNFEEEQQCLESCR 442
>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
sapiens]
Length = 352
Score = 89.4 bits (220), Expect = 4e-18
Identities = 51/148 (34%), Positives = 64/148 (43%), Gaps = 36/148 (24%)
Query: 120 EKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGP 179
+K D C L G C G +RYFYN + CE F+YGGC+GN NNF T +EC C
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT-- 283
Query: 180 NGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVI 239
+ C P RG CRA + +++V
Sbjct: 284 ----------------------------------VAACNLPIVRGPCRAFIQLWAFDAVK 309
Query: 240 GKCRPFKYSGCGGNENNFTSKQECLRAC 267
GKC F Y GC GN N F S++EC C
Sbjct: 310 GKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 77.8 bits (190), Expect = 1e-14
Identities = 41/122 (33%), Positives = 56/122 (45%), Gaps = 15/122 (12%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
C GPC + R+F+N + CE F YGGC GN N F + +EC + C A
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---- 286
Query: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
C L G CR +I + ++ +C F YGGC GN N F + +EC+
Sbjct: 287 -----------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECRE 335
Query: 174 IC 175
C
Sbjct: 336 YC 337
Score = 52.0 bits (123), Expect = 7e-07
Identities = 20/52 (38%), Positives = 29/52 (55%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
C G C +R++YN C F+Y GC GN NNF +++ECL+ C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 78.6 bits (192), Expect = 6e-15
Identities = 42/122 (34%), Positives = 52/122 (42%), Gaps = 13/122 (10%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
C D C R+ F+ C F +G C N N FE+ E C C
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAA-- 385
Query: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
C L G C+ Y R+ YN+QT QC+ F YGGC GN NNFE+ E C+
Sbjct: 386 -----------CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEE 434
Query: 174 IC 175
C
Sbjct: 435 SC 436
Score = 76.6 bits (187), Expect = 2e-14
Identities = 44/143 (30%), Positives = 58/143 (40%), Gaps = 34/143 (23%)
Query: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQV 184
C D C TR+ ++ Q C F +G C N+N+FET E C C GP
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAA-- 385
Query: 185 DNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRP 244
C PA +G C+A R+ YNS G+C+
Sbjct: 386 --------------------------------CSLPALQGPCKAYAPRWAYNSQTGQCQS 413
Query: 245 FKYSGCGGNENNFTSKQECLRAC 267
F Y GC GN NNF S++ C +C
Sbjct: 414 FVYGGCEGNGNNFESREACEESC 436
Score = 67.8 bits (164), Expect = 1e-11
Identities = 31/77 (40%), Positives = 42/77 (54%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
C+ A GPCKA R+ +N T QC+ F+YGGCEGN N FES E C++ C N+
Sbjct: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRC 445
Query: 114 KTTLQQEKPDFCFLEED 130
+ ++K F D
Sbjct: 446 RACKPRQKLVTSFCRSD 462
Score = 41.6 bits (96), Expect = 9e-04
Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 7/78 (8%)
Query: 193 AVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGG 252
A + +P T P+ + CL P D C + R+++++ C F + C
Sbjct: 311 AATSESSPNGTAFPA-------AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHR 363
Query: 253 NENNFTSKQECLRACKKG 270
N N+F + + C+ AC G
Sbjct: 364 NLNHFETYEACMLACMSG 381
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 68.9 bits (167), Expect = 5e-12
Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 34/131 (25%)
Query: 137 YITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNN 196
++ + Y+ Q C F GC G FET E C+ C GP
Sbjct: 313 HLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDA-------------- 358
Query: 197 SLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENN 256
C+ PA +G CR E R+ Y+ ++ +C PF Y GC GN NN
Sbjct: 359 --------------------CVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNN 398
Query: 257 FTSKQECLRAC 267
F S++ C AC
Sbjct: 399 FHSRESCEDAC 409
Score = 68.6 bits (166), Expect = 7e-12
Identities = 35/97 (36%), Positives = 46/97 (47%), Gaps = 13/97 (13%)
Query: 79 CEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYI 138
C F GC+G FE+ E C++ C R D C L G CRG+
Sbjct: 326 CMTFPARGCDGAARGFETYEACQQACARGPG-------------DACVLPAVQGPCRGWE 372
Query: 139 TRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
R+ Y+ +QC F YGGC GN NNF + E C++ C
Sbjct: 373 PRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 55.8 bits (133), Expect = 5e-08
Identities = 22/51 (43%), Positives = 29/51 (56%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
C A GPC+ R+ ++ +QC F+YGGCEGN N F S E C+ C
Sbjct: 359 CVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 30.8 bits (68), Expect = 1.6
Identities = 12/38 (31%), Positives = 19/38 (50%)
Query: 233 FYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKG 270
++Y+ G C F GC G F + + C +AC +G
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG 354
>gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo
sapiens]
Length = 89
Score = 67.8 bits (164), Expect = 1e-11
Identities = 28/56 (50%), Positives = 36/56 (64%)
Query: 49 LMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
L+ + CAF + GPC+ M R+FFN T +CE F YGGC GN N F E+C+K C
Sbjct: 31 LLPNVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
Score = 65.5 bits (158), Expect = 6e-11
Identities = 26/67 (38%), Positives = 42/67 (62%)
Query: 110 NRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLE 169
+ + + T++ P+ C + G C+ Y+TR+F+N +T +CE F YGGC GN NNF E
Sbjct: 21 SELARDTIKDLLPNVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKE 80
Query: 170 ECKNICE 176
+C+ C+
Sbjct: 81 KCEKFCK 87
Score = 60.5 bits (145), Expect = 2e-09
Identities = 23/55 (41%), Positives = 34/55 (61%)
Query: 214 PSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
P+ C P ++G C+ R+++N G+C F Y GCGGN NNF K++C + CK
Sbjct: 33 PNVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 87
>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
sapiens]
Length = 770
Score = 65.5 bits (158), Expect = 6e-11
Identities = 27/80 (33%), Positives = 48/80 (60%)
Query: 37 TIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFES 96
T T T +++ C+ +A+ GPC+A++ R++F++ +C F YGGC GN+N F++
Sbjct: 274 TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDT 333
Query: 97 LEECKKMCTRDNANRIIKTT 116
E C +C + ++KTT
Sbjct: 334 EEYCMAVCGSAMSQSLLKTT 353
Score = 62.8 bits (151), Expect = 4e-10
Identities = 26/61 (42%), Positives = 36/61 (59%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
C A+ G CRA +R+Y++ GKC PF Y GCGGN NNF +++ C+ C Q +
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLL 350
Query: 277 K 277
K
Sbjct: 351 K 351
Score = 52.8 bits (125), Expect = 4e-07
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 86 GCEGNQNRFESLEECKKMCTRDNANRIIKT-TLQQEKPDFCFLEEDPGICRGYITRYFYN 144
G E + E EE + T T ++++ + C + + G CR I+R++++
Sbjct: 251 GDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFD 310
Query: 145 NQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
+C F YGGC GN NNF+T E C +C
Sbjct: 311 VTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
sapiens]
Length = 714
Score = 65.5 bits (158), Expect = 6e-11
Identities = 27/80 (33%), Positives = 48/80 (60%)
Query: 37 TIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFES 96
T T T +++ C+ +A+ GPC+A++ R++F++ +C F YGGC GN+N F++
Sbjct: 218 TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDT 277
Query: 97 LEECKKMCTRDNANRIIKTT 116
E C +C + ++KTT
Sbjct: 278 EEYCMAVCGSAMSQSLLKTT 297
Score = 62.8 bits (151), Expect = 4e-10
Identities = 26/61 (42%), Positives = 36/61 (59%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
C A+ G CRA +R+Y++ GKC PF Y GCGGN NNF +++ C+ C Q +
Sbjct: 235 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLL 294
Query: 277 K 277
K
Sbjct: 295 K 295
Score = 52.8 bits (125), Expect = 4e-07
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 86 GCEGNQNRFESLEECKKMCTRDNANRIIKT-TLQQEKPDFCFLEEDPGICRGYITRYFYN 144
G E + E EE + T T ++++ + C + + G CR I+R++++
Sbjct: 195 GDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFD 254
Query: 145 NQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
+C F YGGC GN NNF+T E C +C
Sbjct: 255 VTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 285
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 64.3 bits (155), Expect = 1e-10
Identities = 25/53 (47%), Positives = 35/53 (66%)
Query: 123 DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
D C L +D G CR +I +++Y+ TK C RF YGGC GN N F + +EC+ +C
Sbjct: 2904 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 2956
Score = 60.8 bits (146), Expect = 1e-09
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Query: 23 PAPLNADSEEDEEHTIITDTELPPLKLMHS-FCAFKADDGPCKAIMKRFFFNIFTRQCEE 81
P P A S ++ TE PL L + C D+G C+ + +++++ T+ C
Sbjct: 2876 PPPQPARSASSSTINLMVSTE--PLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCAR 2933
Query: 82 FIYGGCEGNQNRFESLEECKKMC 104
F YGGC GN+N+F S +EC+K+C
Sbjct: 2934 FWYGGCGGNENKFGSQKECEKVC 2956
Score = 54.3 bits (129), Expect = 1e-07
Identities = 23/51 (45%), Positives = 29/51 (56%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C P D G CR ++YY+ C F Y GCGGNEN F S++EC + C
Sbjct: 2906 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 2956
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 64.3 bits (155), Expect = 1e-10
Identities = 25/53 (47%), Positives = 35/53 (66%)
Query: 123 DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
D C L +D G CR +I +++Y+ TK C RF YGGC GN N F + +EC+ +C
Sbjct: 3110 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 3162
Score = 60.8 bits (146), Expect = 1e-09
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Query: 23 PAPLNADSEEDEEHTIITDTELPPLKLMHS-FCAFKADDGPCKAIMKRFFFNIFTRQCEE 81
P P A S ++ TE PL L + C D+G C+ + +++++ T+ C
Sbjct: 3082 PPPQPARSASSSTINLMVSTE--PLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCAR 3139
Query: 82 FIYGGCEGNQNRFESLEECKKMC 104
F YGGC GN+N+F S +EC+K+C
Sbjct: 3140 FWYGGCGGNENKFGSQKECEKVC 3162
Score = 54.3 bits (129), Expect = 1e-07
Identities = 23/51 (45%), Positives = 29/51 (56%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C P D G CR ++YY+ C F Y GCGGNEN F S++EC + C
Sbjct: 3112 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 3162
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 64.3 bits (155), Expect = 1e-10
Identities = 25/53 (47%), Positives = 35/53 (66%)
Query: 123 DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
D C L +D G CR +I +++Y+ TK C RF YGGC GN N F + +EC+ +C
Sbjct: 2503 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 2555
Score = 60.8 bits (146), Expect = 1e-09
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Query: 23 PAPLNADSEEDEEHTIITDTELPPLKLMHS-FCAFKADDGPCKAIMKRFFFNIFTRQCEE 81
P P A S ++ TE PL L + C D+G C+ + +++++ T+ C
Sbjct: 2475 PPPQPARSASSSTINLMVSTE--PLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCAR 2532
Query: 82 FIYGGCEGNQNRFESLEECKKMC 104
F YGGC GN+N+F S +EC+K+C
Sbjct: 2533 FWYGGCGGNENKFGSQKECEKVC 2555
Score = 54.3 bits (129), Expect = 1e-07
Identities = 23/51 (45%), Positives = 29/51 (56%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C P D G CR ++YY+ C F Y GCGGNEN F S++EC + C
Sbjct: 2505 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 2555
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 61.6 bits (148), Expect = 8e-10
Identities = 24/51 (47%), Positives = 36/51 (70%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
C+ +A GPC+A+M R++F++ +C FIYGGC GN+N FES + C +C
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 55.1 bits (131), Expect = 8e-08
Identities = 25/52 (48%), Positives = 30/52 (57%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
C A G CRA R+Y++ GKC F Y GCGGN NNF S+ C+ CK
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 50.8 bits (120), Expect = 1e-06
Identities = 21/52 (40%), Positives = 31/52 (59%)
Query: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICE 176
C E G CR + R++++ +C RF YGGC GN NNFE+ + C +C+
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 61.6 bits (148), Expect = 8e-10
Identities = 24/51 (47%), Positives = 36/51 (70%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
C+ +A GPC+A+M R++F++ +C FIYGGC GN+N FES + C +C
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 55.1 bits (131), Expect = 8e-08
Identities = 25/52 (48%), Positives = 30/52 (57%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
C A G CRA R+Y++ GKC F Y GCGGN NNF S+ C+ CK
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 50.8 bits (120), Expect = 1e-06
Identities = 21/52 (40%), Positives = 31/52 (59%)
Query: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICE 176
C E G CR + R++++ +C RF YGGC GN NNFE+ + C +C+
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
sapiens]
Length = 751
Score = 60.8 bits (146), Expect = 1e-09
Identities = 24/68 (35%), Positives = 42/68 (61%)
Query: 37 TIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFES 96
T T T +++ C+ +A+ GPC+A++ R++F++ +C F YGGC GN+N F++
Sbjct: 274 TTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDT 333
Query: 97 LEECKKMC 104
E C +C
Sbjct: 334 EEYCMAVC 341
Score = 60.8 bits (146), Expect = 1e-09
Identities = 24/51 (47%), Positives = 33/51 (64%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C A+ G CRA +R+Y++ GKC PF Y GCGGN NNF +++ C+ C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 52.8 bits (125), Expect = 4e-07
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 86 GCEGNQNRFESLEECKKMCTRDNANRIIKT-TLQQEKPDFCFLEEDPGICRGYITRYFYN 144
G E + E EE + T T ++++ + C + + G CR I+R++++
Sbjct: 251 GDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFD 310
Query: 145 NQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
+C F YGGC GN NNF+T E C +C
Sbjct: 311 VTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>gi|145309328 papilin [Homo sapiens]
Length = 1251
Score = 58.5 bits (140), Expect = 7e-09
Identities = 24/55 (43%), Positives = 34/55 (61%)
Query: 214 PSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
P CL P+ G C R+Y+ + +G+C F Y GC GN NNF S+QEC+ +C+
Sbjct: 724 PVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQ 778
Score = 55.1 bits (131), Expect = 8e-08
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Query: 122 PDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICE---DG 178
P C L G C + R+++ QC RF YGGC GN NNF + +EC + C+ G
Sbjct: 724 PVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQGSLHG 783
Query: 179 PNGFQVDNYGTQLNAVNNSLTPQSTKVPS 207
P Q G + +P + PS
Sbjct: 784 PRRPQPGASGRSTHTDGGGSSPAGEQEPS 812
Score = 46.6 bits (109), Expect = 3e-05
Identities = 20/51 (39%), Positives = 24/51 (47%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
C + G C R++F QC F YGGC GN N F S +EC C
Sbjct: 727 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 777
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 57.8 bits (138), Expect = 1e-08
Identities = 39/122 (31%), Positives = 53/122 (43%), Gaps = 25/122 (20%)
Query: 182 FQVDNYGTQLNAV---NNSLTPQSTKVP------------SLFEFHGPS--W-----CLT 219
+ D G+QL+AV S + +VP S+ E+ P W C
Sbjct: 2819 YAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSL 2878
Query: 220 PADRGLCRANENRFYYNSVIGK---CRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
P D G C A R+Y+ +V G C PF Y GCGGN N F +++ C R C +Q
Sbjct: 2879 PLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRCPPRVVQSQG 2938
Query: 277 KG 278
G
Sbjct: 2939 TG 2940
Score = 49.7 bits (117), Expect = 3e-06
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFT---RQCEEFIYGGCEGNQNRFESLEECKKMC 104
C+ D+G C A R++ T C F+YGGC GN NRF + E C++ C
Sbjct: 2876 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
Score = 48.9 bits (115), Expect = 6e-06
Identities = 27/73 (36%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 120 EKPDFCFLEEDPGICRGYITRYFYN---NQTKQCERFKYGGCLGNMNNFETLEECKNICE 176
+ D C L D G C Y R+++ T+ C F YGGC GN N F T E C+ C
Sbjct: 2871 DSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRCP 2930
Query: 177 DGPNGFQVDNYGT 189
P Q GT
Sbjct: 2931 --PRVVQSQGTGT 2941
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 56.6 bits (135), Expect = 3e-08
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 74 IFTRQCEEFIYGGCEGNQN----RFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEE 129
+F R+C + I CE + + ++ KK C + + K D C + +
Sbjct: 28 LFPRRCPK-IREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDL-----KQDVCEMPK 81
Query: 130 DPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
+ G C Y ++Y+ + C F YGGC GN NNF++ C N C++
Sbjct: 82 ETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKN 129
Score = 50.4 bits (119), Expect = 2e-06
Identities = 20/58 (34%), Positives = 28/58 (48%)
Query: 47 LKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
L L C + GPC A ++++ C F+YGGC+GN N F+S C C
Sbjct: 70 LDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 49.7 bits (117), Expect = 3e-06
Identities = 22/52 (42%), Positives = 26/52 (50%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
C P + G C A ++Y+ C F Y GC GN NNF SK CL CK
Sbjct: 77 CEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 128
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 55.8 bits (133), Expect = 5e-08
Identities = 21/57 (36%), Positives = 32/57 (56%)
Query: 121 KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
K D C + ++ G C Y ++Y+ + C F YGGC GN NNF++ C N C++
Sbjct: 57 KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKN 113
Score = 50.4 bits (119), Expect = 2e-06
Identities = 20/58 (34%), Positives = 28/58 (48%)
Query: 47 LKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
L L C + GPC A ++++ C F+YGGC+GN N F+S C C
Sbjct: 54 LDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
Score = 49.7 bits (117), Expect = 3e-06
Identities = 22/52 (42%), Positives = 26/52 (50%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
C P + G C A ++Y+ C F Y GC GN NNF SK CL CK
Sbjct: 61 CEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 112
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 52.0 bits (123), Expect = 7e-07
Identities = 21/67 (31%), Positives = 34/67 (50%)
Query: 112 IIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEEC 171
++ T + + C PG C Y+ R++Y+ Q C RF + GC G+ N F + +EC
Sbjct: 1059 LLSTPVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKEC 1118
Query: 172 KNICEDG 178
+ C G
Sbjct: 1119 QETCIQG 1125
Score = 47.0 bits (110), Expect = 2e-05
Identities = 20/54 (37%), Positives = 28/54 (51%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKG 270
CL G C R+YY+ + C F +SGC G+ N F S++EC C +G
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG 1125
Score = 40.4 bits (93), Expect = 0.002
Identities = 16/51 (31%), Positives = 26/51 (50%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
C G C + R++++ C F + GC G+ NRF S +EC++ C
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 51.2 bits (121), Expect = 1e-06
Identities = 20/51 (39%), Positives = 28/51 (54%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C+ P G C R++++ +C PFKY GC GN NNF ++ C AC
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
Score = 43.1 bits (100), Expect = 3e-04
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC---TRDNAN 110
C G C +R+ F+ +C F Y GCEGN N F + + C+ C +D
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDGQC 154
Query: 111 RIIKTTLQQEKPDFCFLEED 130
+ T ++E P C + D
Sbjct: 155 PLFPFTERKECPPSCHSDID 174
Score = 41.6 bits (96), Expect = 9e-04
Identities = 18/51 (35%), Positives = 25/51 (49%)
Query: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
C L G C R+ ++ + +C FKY GC GN NNF + C+ C
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 51.2 bits (121), Expect = 1e-06
Identities = 20/51 (39%), Positives = 28/51 (54%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C+ P G C R++++ +C PFKY GC GN NNF ++ C AC
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
Score = 43.1 bits (100), Expect = 3e-04
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC---TRDNAN 110
C G C +R+ F+ +C F Y GCEGN N F + + C+ C +D
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDGQC 154
Query: 111 RIIKTTLQQEKPDFCFLEED 130
+ T ++E P C + D
Sbjct: 155 PLFPFTERKECPPSCHSDID 174
Score = 41.6 bits (96), Expect = 9e-04
Identities = 18/51 (35%), Positives = 25/51 (49%)
Query: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
C L G C R+ ++ + +C FKY GC GN NNF + C+ C
Sbjct: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
>gi|110626171 serine peptidase inhibitor, Kunitz type 4 [Homo
sapiens]
Length = 99
Score = 49.3 bits (116), Expect = 4e-06
Identities = 23/53 (43%), Positives = 31/53 (58%)
Query: 123 DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
D C L+ + G C RYFYN +K+CE F + GC GN+NNF+ E + C
Sbjct: 39 DPCKLDMNFGSCYEVHFRYFYNRTSKRCETFVFSGCNGNLNNFKLKIEREVAC 91
Score = 43.1 bits (100), Expect = 3e-04
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
C + G C + R+F+N +++CE F++ GC GN N F+ E + C
Sbjct: 41 CKLDMNFGSCYEVHFRYFYNRTSKRCETFVFSGCNGNLNNFKLKIEREVAC 91
Score = 41.6 bits (96), Expect = 9e-04
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
C + G C R++YN +C F +SGC GN NNF K E AC
Sbjct: 41 CKLDMNFGSCYEVHFRYFYNRTSKRCETFVFSGCNGNLNNFKLKIEREVAC 91
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,410,065
Number of Sequences: 37866
Number of extensions: 658437
Number of successful extensions: 1323
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1206
Number of HSP's gapped (non-prelim): 86
length of query: 304
length of database: 18,247,518
effective HSP length: 102
effective length of query: 202
effective length of database: 14,385,186
effective search space: 2905807572
effective search space used: 2905807572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.