Guide to the Human Genome
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Search of human proteins with 5453710

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453710 LIM and SH3 protein 1 [Homo sapiens]                       551   e-157
gi|47087157 nebulette non-muscle isoform [Homo sapiens]               340   7e-94
gi|115527120 nebulin [Homo sapiens]                                   123   1e-28
gi|5453758 nebulette sarcomeric isoform [Homo sapiens]                120   9e-28
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa...   105   3e-23
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa...   105   3e-23
gi|20357552 cortactin isoform a [Homo sapiens]                         66   3e-11
gi|20357556 cortactin isoform b [Homo sapiens]                         66   3e-11
gi|21361670 drebrin-like isoform a [Homo sapiens]                      64   1e-10
gi|62198235 drebrin-like isoform b [Homo sapiens]                      63   3e-10
gi|171906575 drebrin-like isoform c [Homo sapiens]                     62   4e-10
gi|19224660 protein kinase C and casein kinase substrate in neur...    60   3e-09
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ...    59   4e-09
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ...    59   4e-09
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ...    59   4e-09
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ...    59   4e-09
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ...    59   4e-09
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ...    59   4e-09
gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ...    59   4e-09
gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s...    59   4e-09
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s...    59   4e-09
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ...    59   4e-09
gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens]         59   4e-09
gi|109689723 abl interactor 2 [Homo sapiens]                           58   1e-08
gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s...    57   2e-08
gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo s...    57   2e-08
gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens]           57   2e-08
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]         56   3e-08
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]         56   3e-08
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]         56   3e-08

>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
          Length = 261

 Score =  551 bits (1420), Expect = e-157
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 60
           MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ
Sbjct: 1   MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 60

Query: 61  SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120
           SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI
Sbjct: 61  SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120

Query: 121 KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA 180
           KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA
Sbjct: 121 KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA 180

Query: 181 QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240
           QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM
Sbjct: 181 QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240

Query: 241 YGTVERTGDTGMLPANYVEAI 261
           YGTVERTGDTGMLPANYVEAI
Sbjct: 241 YGTVERTGDTGMLPANYVEAI 261


>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
          Length = 270

 Score =  340 bits (872), Expect = 7e-94
 Identities = 170/277 (61%), Positives = 200/277 (72%), Gaps = 24/277 (8%)

Query: 1   MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 60
           MNP CARCGK+VYPTEKVNCLDK+WHK CFHCE CKM LNM NYKGYEKKPYCNAHYPKQ
Sbjct: 1   MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 60

Query: 61  SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120
           SFT VADTPENLRLKQQSELQSQV+YK +FE++KG+GFS+V DTPELQR+K+TQ+QISN+
Sbjct: 61  SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120

Query: 121 KYHEEFEKSRMGPSGGEGMEP---------ERRDSQDGSSYRRPLEQQQPHHIPTS---- 167
           KYHE+FEK++     G G  P          R+++Q  S      +   PH +       
Sbjct: 121 KYHEDFEKTK-----GRGFTPVVDDPVTERVRKNTQVVSD--AAYKGVHPHIVEMDRRPG 173

Query: 168 ---APVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQ 224
              APV     QQ  +Q Y GY    +  S++        + YRA+YDYSA DEDEVSF+
Sbjct: 174 IIVAPVLPGAYQQSHSQGY-GYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFR 232

Query: 225 DGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           DGD IVNVQ IDDGWMYGTV+RTG TGMLPANY+E +
Sbjct: 233 DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score =  123 bits (309), Expect = 1e-28
 Identities = 94/258 (36%), Positives = 117/258 (45%), Gaps = 66/258 (25%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            V DTPE  R+++     S V+Y E+FEK+KG    VV D P  +R+KK     S+I Y  
Sbjct: 6417 VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTD-PITERVKKNMQDFSDINYRG 6475

Query: 125  ------EFEKSR---------------MGPSGGEGMEPERRDSQDGSSY-------RRPL 156
                  E E+ R                 P      +P   + Q  S +       RR  
Sbjct: 6476 IQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSR 6535

Query: 157  EQQQP--------------------HHIPTSAPVYQQPQQQPVAQSYGGYKEPAAP---- 192
            EQ +                     HH+ T    Y       V+ +Y   K    P    
Sbjct: 6536 EQSRSASALSISGGEEKSEHSEAPDHHLST----YSDGGVFAVSTAYKHAKTTELPQQRS 6591

Query: 193  ---------VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGT 243
                     VS   S P   GK +RA+YDY AAD DEVSF+DGD I+NVQ ID+GWMYGT
Sbjct: 6592 SSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGT 6651

Query: 244  VERTGDTGMLPANYVEAI 261
            V+RTG TGMLPANYVEAI
Sbjct: 6652 VQRTGRTGMLPANYVEAI 6669



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 31/90 (34%), Positives = 55/90 (61%), Gaps = 8/90 (8%)

Query: 41   MKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100
            +K  K YEK         K  FT + DTPE+LR  + ++  S + YK E+ K K +G++ 
Sbjct: 5439 IKYRKNYEKS--------KDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTT 5490

Query: 101  VADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            + DTP L  ++K +D++S++KY E +++++
Sbjct: 5491 IHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520



 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 39/112 (34%), Positives = 56/112 (50%), Gaps = 4/112 (3%)

Query: 22   DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQS 78
            D  W K   C+  +T   TL  KN   Y K  Y       K  F  VAD+P N   K  +
Sbjct: 5339 DLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYAT 5398

Query: 79   ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            +L ++ +Y+ ++E+ K K + +V D P     K   DQIS IKY + +EKS+
Sbjct: 5399 QLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 27/55 (49%), Positives = 38/55 (69%)

Query: 68  TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
           TP     ++  +L S  +YKE+FEK KG+ ++   DTPEL+RIKK QDQ+S +KY
Sbjct: 83  TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKY 137



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 54   NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113
            +A   K +FT V DTPE +  +Q   L SQ +YKE+ EK+    +  V DTPE+QR+++ 
Sbjct: 6052 SAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSY-YETVLDTPEIQRVREN 6110

Query: 114  QDQISNIKYHEEFEKSR 130
            Q   S ++Y  + + S+
Sbjct: 6111 QKNFSLLQYQCDLKNSK 6127



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 6/84 (7%)

Query: 42   KNYKGYEKKPY-CNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100
            +N K +    Y C+    K   T+V DTPE LR+K+  +  S V YKE+         + 
Sbjct: 6109 ENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPG-----TA 6163

Query: 101  VADTPELQRIKKTQDQISNIKYHE 124
            +  TPE+ R+K+TQD IS++KY E
Sbjct: 6164 IGKTPEMMRVKQTQDHISSVKYKE 6187



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 28/63 (44%), Positives = 39/63 (61%)

Query: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
            TPE  R K+  E  S V Y + F K      + V DTPE++R+++TQ  IS +KYHE+FE
Sbjct: 6384 TPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFE 6443

Query: 128  KSR 130
            K +
Sbjct: 6444 KHK 6446



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 10/101 (9%)

Query: 31   HCETCKMTLNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89
            H +     +N K Y+  YE++        K  + +V D P +L  K   +  SQ++Y++ 
Sbjct: 5393 HFKYATQLMNEKKYRADYEQR--------KDKYHLVVDEPRHLLAKTAGDQISQIKYRKN 5444

Query: 90   FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            +EK+K K F+ + DTPE  R  K   QIS+I Y  E+ K++
Sbjct: 5445 YEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAK 5484



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 32/111 (28%), Positives = 61/111 (54%), Gaps = 6/111 (5%)

Query: 23  KFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQS 82
           K+    CF     +M  +  + + Y++      +   Q + M  +TPE    K+     S
Sbjct: 288 KWSETPCFEVANARMNADNISTRKYQED---FENMKDQIYFMQTETPEYKMNKKAGVAAS 344

Query: 83  QVRYKEEFEKNKGKG-FSVV--ADTPELQRIKKTQDQISNIKYHEEFEKSR 130
           +V+YKE++EKNKGK  ++V+  ++ P+L+++K   D +S+  Y E +EK++
Sbjct: 345 KVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTK 395



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 36/97 (37%), Positives = 49/97 (50%), Gaps = 10/97 (10%)

Query: 31   HCETCKMTLNMKNYK-GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89
            H +  K  ++ K YK  YEK         K  +T V DTP  +R K+     S +RYKE 
Sbjct: 5218 HAKDVKDMVSEKKYKIQYEKM--------KDKYTPVPDTPILIRAKRAYWNASDLRYKET 5269

Query: 90   FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126
            F+K KGK +  V D  ++   +K  D IS IKY E +
Sbjct: 5270 FQKTKGK-YHTVKDALDIVYHRKVTDDISKIKYKENY 5305



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 9/156 (5%)

Query: 41  MKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFS 99
           +KN   + KK Y       K  F    D+PE  R+ Q  +  S V YK+   + + + F+
Sbjct: 196 VKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQ-FT 254

Query: 100 VVADTPELQRIKKTQDQISNIKYHEEFEKSRMG-----PSGGEGMEPERRDSQDGSSYRR 154
            +AD P+++  KK  +Q+S  KY E++E    G     P           D+     Y+ 
Sbjct: 255 PLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQE 314

Query: 155 PLE--QQQPHHIPTSAPVYQQPQQQPVAQSYGGYKE 188
             E  + Q + + T  P Y+  ++  VA S   YKE
Sbjct: 315 DFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKE 350



 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 19/152 (12%)

Query: 16   EKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLK 75
            EK N           H +  K   + K YK        +A      +  V DTPE  R++
Sbjct: 6056 EKANFTSVVDTPEIIHAQQVKNLSSQKKYKE-------DAEKSMSYYETVLDTPEIQRVR 6108

Query: 76   QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSG 135
            +  +  S ++Y+ + + +KGK  +VV DTPE+ R+K+ Q   S++ Y E+     + P  
Sbjct: 6109 ENQKNFSLLQYQCDLKNSKGK-ITVVQDTPEILRVKENQKNFSSVLYKED-----VSPGT 6162

Query: 136  GEGMEPER---RDSQDGSS---YRRPLEQQQP 161
              G  PE    + +QD  S   Y+  + Q  P
Sbjct: 6163 AIGKTPEMMRVKQTQDHISSVKYKEAIGQGTP 6194



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 9/99 (9%)

Query: 34   TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93
            T ++  + +  K YEK         K  +  + D  E L LK+ +ELQS V+YKE++EK 
Sbjct: 5858 TSQLASSYQYKKKYEKS--------KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKE 5909

Query: 94   KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMG 132
            +GK   +  +TP     K++Q   S  +Y +++E+S  G
Sbjct: 5910 RGKPM-LDFETPTYITAKESQQMQSGKEYRKDYEESIKG 5947



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 8/101 (7%)

Query: 63   TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
            T +A TPE  R+K   E  S V YKE    N GK  +    TPE+QR+K+ Q+ IS++ Y
Sbjct: 6286 TPLAVTPEMERVKHNQENISSVLYKE----NVGKATATPV-TPEMQRVKRNQENISSVLY 6340

Query: 123  HEEFEKSRMGPSGGEGMEPERRDSQDGSS--YRRPLEQQQP 161
             E   K+   P   E ME  +R+ ++ SS  Y+  + +  P
Sbjct: 6341 KENLGKATPTPFTPE-MERVKRNQENFSSVLYKENMRKATP 6380



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 23/66 (34%), Positives = 40/66 (60%), Gaps = 1/66 (1%)

Query: 64   MVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYH 123
            M  +TP+ +R +  +++ SQ++YK+  E  K   F+ V DTPE+   ++ ++  S  KY 
Sbjct: 6027 MANETPDFMRARNATDIASQIKYKQSAEMEKA-NFTSVVDTPEIIHAQQVKNLSSQKKYK 6085

Query: 124  EEFEKS 129
            E+ EKS
Sbjct: 6086 EDAEKS 6091



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 5/62 (8%)

Query: 63   TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
            T +  TPE +R+KQ  +  S V+YKE      G+G + + D PE++R+K+TQ  IS++ Y
Sbjct: 6162 TAIGKTPEMMRVKQTQDHISSVKYKEAI----GQG-TPIPDLPEVKRVKETQKHISSVMY 6216

Query: 123  HE 124
             E
Sbjct: 6217 KE 6218



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 6/89 (6%)

Query: 63   TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
            T + D PE  R+K+  +  S V YKE    N G G      TPE++R+K+ Q+  S++ Y
Sbjct: 6193 TPIPDLPEVKRVKETQKHISSVMYKE----NLGTGIPTTV-TPEIERVKRNQENFSSVLY 6247

Query: 123  HEEFEKSRMGPSGGEGMEPERRDSQDGSS 151
             E   K    P   E ME  +R+ ++ SS
Sbjct: 6248 KENLGKGIPTPITPE-MERVKRNQENFSS 6275



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 1/111 (0%)

Query: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91
            +T ++ L   N     K  Y  A    K S  ++ DTP+ L  K  S   SQ  Y + ++
Sbjct: 3676 DTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWD 3735

Query: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142
            ++K K + + AD   ++  K ++D  S+ KY E +EK +    G + +E +
Sbjct: 3736 ESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDD 3786



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 47   YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106
            Y K    N HY     T VAD P+  +  Q ++  S+V Y+ +  K    G S++   P+
Sbjct: 5726 YRKDAKENLHY-----TTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG-RPD 5779

Query: 107  LQRIKKTQDQISNIKYHEEFEKSR 130
            ++  KK     S +KY E F+K +
Sbjct: 5780 IEMAKKAAKLSSQVKYRENFDKEK 5803



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%)

Query: 60   QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVA-DTPELQRIKKTQDQI 117
            +  T + DTP+ LR K  +++ ++  YK + E   KG+G + +A +TP+  R +   D  
Sbjct: 5985 KGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIA 6044

Query: 118  SNIKYHEEFEKSR 130
            S IKY +  E  +
Sbjct: 6045 SQIKYKQSAEMEK 6057



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 36   KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95
            ++T N +     + K     +YP  +F  V D PE +  K  S  QS V+YKE F K KG
Sbjct: 4376 RVTKNQEMMSQIKYKKNALENYP--NFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKG 4433

Query: 96   KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            K ++   DTP +   K      S I Y   +E ++
Sbjct: 4434 K-YTFSPDTPHISHSKDMGKLYSTILYKGAWEGTK 4467



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 23/98 (23%), Positives = 54/98 (55%), Gaps = 6/98 (6%)

Query: 33   ETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92
            +T    ++   YK + KK     H  + S+T + +T + + +K+ ++  S   YK++F K
Sbjct: 5641 KTVSNLVSENKYKDHVKK-----HLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVK 5695

Query: 93   NKGK-GFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129
             KGK  +S++ + PE++   +   + S++ Y ++ +++
Sbjct: 5696 EKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKEN 5733



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 24/75 (32%), Positives = 37/75 (49%)

Query: 54   NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113
            N H  K  +T V +T +  R +    L S   YKE +++ K   + + + T  L   K  
Sbjct: 4672 NYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQ 4731

Query: 114  QDQISNIKYHEEFEK 128
            +   S+IKY EE+EK
Sbjct: 4732 KHLASHIKYREEYEK 4746



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
            TPE  R+K+  E  S V YKE   K      +    TPE++R K+ Q+ IS++ Y + F 
Sbjct: 6353 TPEMERVKRNQENFSSVLYKENMRKA-----TPTPVTPEMERAKRNQENISSVLYSDSFR 6407

Query: 128  KSRMGPSGGEGMEPERR 144
            K   G +      PE R
Sbjct: 6408 KQIQGKAAYVLDTPEMR 6424



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 1/117 (0%)

Query: 27   KACFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVR 85
            K  +  +T +  LN  N    +K+ Y    +  K +  ++ DTP+ L  +      S   
Sbjct: 1724 KFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKL 1783

Query: 86   YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142
            YK  +E+ K KG+ +  D   ++  + ++D  S+ KY + +E+++    G   +E +
Sbjct: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDD 1840



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 65   VADTPENLRLKQ---QSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            V D  E+L +      S+L S  +YK+++EK+KG  +  + D  E   +K+  +  S +K
Sbjct: 5843 VTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGH-YHTIPDNLEQLHLKEATELQSIVK 5901

Query: 122  YHEEFEKSRMGP-----SGGEGMEPERRDSQDGSSYRRPLEQ 158
            Y E++EK R  P     +       E +  Q G  YR+  E+
Sbjct: 5902 YKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEE 5943



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K    ++ DTP+ L+ KQ   L SQ  YK  +E+   KG+ +  D   +Q  K ++D  S
Sbjct: 2245 KTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIAS 2304

Query: 119  NIKYHEEFEK 128
            + KY + + K
Sbjct: 2305 DYKYKQGYRK 2314



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 28/110 (25%), Positives = 55/110 (50%), Gaps = 6/110 (5%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            +T + DTPE +  K  +E  S  +Y+E ++K+K     ++ DTPE+   +     +SN  
Sbjct: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDK-TSIHIMPDTPEINLARANALNVSNKL 3972

Query: 122  YHEEFEKSRMGPS---GGEGMEPERRDSQDGSSYRRPL--EQQQPHHIPT 166
            Y E +++ + G         ++  +   +  S Y+  L  E+Q+ H++ T
Sbjct: 3973 YREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGT 4022



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 36/107 (33%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQV---------------------------------- 84
            K  FT V DTP+ LR K+  +LQSQ                                   
Sbjct: 5169 KSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSE 5228

Query: 85   -RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
             +YK ++EK K K ++ V DTP L R K+     S+++Y E F+K++
Sbjct: 5229 KKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYKETFQKTK 5274



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 4/98 (4%)

Query: 31   HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90
            H +  K T  M +Y  Y K+ Y   H     +T+       + +++ + + S+  Y+E +
Sbjct: 4969 HFKHIKDTRYMSSYFKY-KEAY--EHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025

Query: 91   EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128
             K K K      DTPE++++KKTQ+ +S + Y  +F K
Sbjct: 5026 HKLKDK-IHTTPDTPEIRQVKKTQEAVSELIYKSDFFK 5062



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 5/61 (8%)

Query: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
            TPE  R+K+  E  S V YKE    N GKG      TPE++R+K+ Q+  S++ Y E   
Sbjct: 6229 TPEIERVKRNQENFSSVLYKE----NLGKGIPTPI-TPEMERVKRNQENFSSVLYKENMG 6283

Query: 128  K 128
            K
Sbjct: 6284 K 6284



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%)

Query: 43  NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102
           NYK   +      H P        DTP  ++ K  +   S   YK+++EK+K K F +  
Sbjct: 525 NYKAKHESEKFKCHIPP-------DTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKV 577

Query: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130
           D   L   K      S++ Y +++EK++
Sbjct: 578 DAIPLLAAKANTKNTSDVMYKKDYEKNK 605



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 43  NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102
           NYK   +      H P       AD P+ ++ +  +   S   YK+++EK+K K F +  
Sbjct: 772 NYKAKHEGEKFKCHIP-------ADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKV 824

Query: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130
           D   L   K      S++ Y +++EKS+
Sbjct: 825 DAIPLLAAKANTKNTSDVMYKKDYEKSK 852



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 49   KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108
            KK Y  A      F  + D P+ +     +++QS   YK+++EK K K ++   D   + 
Sbjct: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK-YNTPHDMFNVV 1147

Query: 109  RIKKTQDQISNIKY 122
              KK QD +SN+ Y
Sbjct: 1148 AAKKAQDVVSNVNY 1161



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%)

Query: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117
           + F +  D    L  K  ++  S V YK+++EK+KGK  G   + D P++    KT    
Sbjct: 818 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQ 877

Query: 118 SNIKYHEEFEKSR 130
           S+ +Y +++EKS+
Sbjct: 878 SDREYRKDYEKSK 890



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 23/72 (31%), Positives = 38/72 (52%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K  +TM  D P+ L+ K  +   S V YK ++     KG +V+ D   +   K +++  S
Sbjct: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328

Query: 119  NIKYHEEFEKSR 130
            + KY E +EKS+
Sbjct: 1329 DYKYKEAYEKSK 1340



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            FT + DTPE +  K  +   S+  Y E ++ +K     V+ DTP++   K     IS   
Sbjct: 3671 FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-TSIHVMPDTPDILLAKSNSANISQKL 3729

Query: 122  YHEEFEKSRM------GPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHI 164
            Y + +++S+M        +         RD      Y+   E+Q+ HHI
Sbjct: 3730 YTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHI 3778



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 23/70 (32%), Positives = 35/70 (50%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K +  ++ DTPE L  KQ     S+  YK   E+ K KG+ +  D   ++  K ++D  S
Sbjct: 2731 KTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIAS 2790

Query: 119  NIKYHEEFEK 128
              KY E + K
Sbjct: 2791 EFKYKEGYRK 2800



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 1/111 (0%)

Query: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91
            ++ +  L   N     K+ Y  A    K    ++ DTPE +  +Q     S+  YK   E
Sbjct: 2947 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANE 3006

Query: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142
            + K KG+ + +D   +   K ++D IS+ KY + + K      G   +E +
Sbjct: 3007 EAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            V DTPE L  K   +L+  ++YK    K +   + +V DTP   +  K+  Q+S+  YH 
Sbjct: 4858 VWDTPEILHAKHAYDLRDDIKYKAHMLKTR-NDYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916

Query: 125  EFEKSRMG 132
            ++  S  G
Sbjct: 4917 DYVHSVRG 4924



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 34   TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93
            T K +  M++ K Y K          ++ T +  TP  L +K  +++ S+  Y+++ E++
Sbjct: 5924 TAKESQQMQSGKEYRKD--YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEES 5981

Query: 94   -KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
             +GKG + + DTP++ R K     ++  +Y  + E
Sbjct: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLE 6016



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA--DTPELQRIKKTQDQI 117
           + F +  D    L  K  ++  S V YK+++EKNKGK   V++  D P++    K     
Sbjct: 571 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQ 630

Query: 118 SNIKYHEEFEKSR 130
           S+  Y E +EK++
Sbjct: 631 SDRLYKENYEKTK 643



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 17/114 (14%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            FT + DTPE +  K  +   ++  Y E ++ +K K   V+ DTPE+   K     ++ I 
Sbjct: 3428 FTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK-----LNRIN 3481

Query: 122  YHEEFEKSRMGPSGGEGME-----------PERRDSQDGSSYRRPLEQQQPHHI 164
            Y ++  K  +  S  EG +              RD      Y+    +Q  HHI
Sbjct: 3482 YSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHI 3535



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 1/64 (1%)

Query: 67   DTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126
            D+ +++R+ +  E+ SQ++YK+   +N    F  V D PE+   K      S++KY E F
Sbjct: 4370 DSVDHVRVTKNQEMMSQIKYKKNALENY-PNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428

Query: 127  EKSR 130
             K++
Sbjct: 4429 NKAK 4432



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 18/72 (25%), Positives = 38/72 (52%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K  +T+  + P+ ++ K  +   S   YK +++K   KG+ +  D   +   K +++  S
Sbjct: 1513 KHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIAS 1572

Query: 119  NIKYHEEFEKSR 130
            + KY E +EK++
Sbjct: 1573 DCKYKEAYEKAK 1584



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            + D PE+   +  ++  S V+YKE+    KG G     DTP+    +K +   S  KY E
Sbjct: 5315 IPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG-CYAYDTPDFTLAEKNKTLYSKYKYKE 5373

Query: 125  EFEKSR 130
             FE+++
Sbjct: 5374 VFERTK 5379



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 19/67 (28%), Positives = 38/67 (56%), Gaps = 1/67 (1%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKG-FSVVADTPELQRIKKTQDQISNIKYH 123
            V DTP+ L  K  S L S+ +YK+  +K+  +G ++ + +T +   +K+    +S+  Y 
Sbjct: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690

Query: 124  EEFEKSR 130
            ++F K +
Sbjct: 5691 KKFVKEK 5697



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 1/97 (1%)

Query: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91
            ++ +  L   N     K+ Y  A    K    ++ DTPE +  +Q     S+  Y++  E
Sbjct: 3190 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAME 3249

Query: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128
            + K +G+ + +D   +   K ++D  S+ KY E + K
Sbjct: 3250 EAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRK 3286



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 56   HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115
            H  K       DTPE  ++K+  E  S++ YK +F K +G   S +  TP++   +   D
Sbjct: 5026 HKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMIS-LPYTPQVIHCRYVGD 5084

Query: 116  QISNIKYHEEFE 127
              S+IKY E+ +
Sbjct: 5085 ITSDIKYKEDLQ 5096



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 30/128 (23%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 31   HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90
            H   C    +   YK    K     HY       + D P+ +  +   ++Q++  YKE++
Sbjct: 4237 HAHHCNDVQSELKYKAEHVKQ--KGHYV--GVPTMRDDPKLVWFEHAGQIQNERLYKEDY 4292

Query: 91   EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDG 149
             K K K  ++ AD   +   K+ Q  +S+I Y     +    P   + ++  +  D Q  
Sbjct: 4293 HKTKAK-INIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351

Query: 150  SSYRRPLE 157
            + YR  LE
Sbjct: 4352 NVYRADLE 4359



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQ 116
            K+ + +  D       K   +  S V+YK+++EK KGK  GF  + D P+L         
Sbjct: 1061 KKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKI 1120

Query: 117  ISNIKYHEEFEKSR 130
             S+ +Y +++EK++
Sbjct: 1121 QSDREYKKDYEKTK 1134



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 1/111 (0%)

Query: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91
            ++  M L   N K   +  Y  A    K    ++ D P+ +  K  +   S   YK   E
Sbjct: 1974 DSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLE 2033

Query: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142
            ++K KG+ +  D   ++  K ++D  S+ KY   +EK +    G   +E +
Sbjct: 2034 ESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDD 2084



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 22   DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFTMVADTPENLRLKQQS 78
            D  W K   C+  +T ++    K+Y    +  Y  A     Q++ +V DTP  +   Q  
Sbjct: 4602 DLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSG 4661

Query: 79   ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128
               S+V+YKE + + K K ++ V +T +  R +  ++  S+  Y E +++
Sbjct: 4662 INASEVKYKENYHQIKDK-YTTVLETVDYDRTRNLKNLYSSNLYKEAWDR 4710



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 1/85 (1%)

Query: 49   KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108
            KK Y  A      F  + D P+ +   Q +++QS   YK+ +EK+K   F    D   + 
Sbjct: 1821 KKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSK-TSFHTPVDMLSVV 1879

Query: 109  RIKKTQDQISNIKYHEEFEKSRMGP 133
              KK+Q+  +N  Y        M P
Sbjct: 1880 AAKKSQEVATNANYRNVIHTYNMLP 1904



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%)

Query: 69   PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQI-SNIKYHEEFE 127
            P+    K+ ++L SQV+Y+E F+K KGK         +L ++ K  + + S +KY  + +
Sbjct: 5778 PDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLK 5837

Query: 128  K 128
            K
Sbjct: 5838 K 5838



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 7/117 (5%)

Query: 42   KNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVV 101
            K  + YEK+     H   QS   + D P+ +      ++QS+  YK+EF+K K K FS  
Sbjct: 3765 KYKEAYEKQK--GHHIGAQS---IEDDPKIMCAIHAGKIQSEREYKKEFQKWKTK-FSSP 3818

Query: 102  ADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157
             D   +   KK Q  +++I Y     +    P   + ++ ++  D Q  + Y+  LE
Sbjct: 3819 VDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLE 3875



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query: 67   DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
            +TP  +  K+  ++QS   Y++++E++ KG+  + +  TP L  +K      S  +Y ++
Sbjct: 5918 ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKD 5977

Query: 126  FEKSRMG 132
             E+S  G
Sbjct: 5978 LEESIRG 5984



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 41/171 (23%), Positives = 65/171 (38%), Gaps = 13/171 (7%)

Query: 27  KACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVA--DTPENLRLKQQSELQSQV 84
           K+  +CET K  L+         K Y +++        V   + P +    + +   S  
Sbjct: 397 KSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDK 456

Query: 85  RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144
            YK E+E+++GKGF     T E + IKK  DQ  +  Y    +K++          P   
Sbjct: 457 NYKAEYEEDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTKFTQVTD---SPVLL 512

Query: 145 DSQDGSSYRRPLEQQQPH-------HIPTSAPVYQQPQQQPVAQSYGGYKE 188
            +Q  S     L  +  H       HIP   P + Q +      S   YK+
Sbjct: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQ 563



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 35/152 (23%), Positives = 60/152 (39%), Gaps = 24/152 (15%)

Query: 35   CKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNK 94
            CK    + +   Y + P       K  FT V D+ E +  K  +   ++  Y E ++K+K
Sbjct: 3164 CKRAAEILSDNIYRQPP------DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 3217

Query: 95   GKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGME-----------PER 143
             +   ++ DTPE+   ++     + I Y E   +  M  +  EG +              
Sbjct: 3218 TQ-VHIMPDTPEIMLARQ-----NKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKAS 3271

Query: 144  RDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQ 175
            RD      Y+    +Q  HHI   A V+  P+
Sbjct: 3272 RDIASDYKYKEAYRKQLGHHIGARA-VHDDPK 3302



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 8/121 (6%)

Query: 10   KIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTP 69
            K VY   K NC  +       H +  K    +     Y+K+   N    K  +    D P
Sbjct: 5513 KEVYQRNKSNCTIE---PDAVHIKAAKDAYKVNTNLDYKKQYEAN----KAHWKWTPDRP 5565

Query: 70   ENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129
            + L+  + S  QS   YK + E  KG   SV  D   +  ++ T  + S++KY E+  K 
Sbjct: 5566 DFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIE-SDLKYKEKHVKE 5624

Query: 130  R 130
            R
Sbjct: 5625 R 5625



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 17/97 (17%)

Query: 36   KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95
            K++L     KGY+ +P               D       K   ++ S  +YK  +EK KG
Sbjct: 2029 KLSLEESKKKGYDLRP---------------DAIPIKAAKASRDIASDYKYKYNYEKGKG 2073

Query: 96   K--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            K  GF  + D P+L    +     S+ +Y + +E ++
Sbjct: 2074 KMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTK 2110



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 66  ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
           ++ P+  +LK   +  S   YKE +EK K K  +   +TP+ +     Q+  S+ KY + 
Sbjct: 367 SENPQLRQLKAAGDALSDKLYKENYEKTKAKSIN-YCETPKFKLDTVLQNFSSDKKYKDS 425

Query: 126 FEKSRMGPSGGEGMEP 141
           + K  +G   G   +P
Sbjct: 426 YLKDILGHYVGSFEDP 441



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 75   KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            K    + S  +YKE +EK+KGK  GF  + D P+L          S+ +Y + +E ++
Sbjct: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK 1378



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            F  + D P+ +     +++QS+  YK++FEK K K FS   D   +   KK Q+ +S++ 
Sbjct: 2322 FRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQELVSDVD 2380

Query: 122  YHEEFEKSRMGPSGGEGMEPER-RDSQDGSSYRRPLE 157
            Y     +    P   + ++ ++  + Q  + Y+  LE
Sbjct: 2381 YKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLE 2417



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            + D P+ +     +++QS   YK+EFEK K K FS   D   +   KK Q  +S+I Y  
Sbjct: 3540 IKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK-FSSPVDMLGVVLAKKCQILVSDIDYKH 3598

Query: 125  EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157
               +    P   + ++  +  D Q  + Y+  LE
Sbjct: 3599 PLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLE 3632



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)

Query: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
            TP+ +  +   ++ S ++YKE+ +  KG G   + DTP++ R +  +   SN  Y ++  
Sbjct: 5073 TPQVIHCRYVGDITSDIKYKEDLQVLKGFG-CFLYDTPDMVRSRHLRKLWSNYLYTDKAR 5131

Query: 128  KSR 130
            K R
Sbjct: 5132 KMR 5134



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 21/84 (25%), Positives = 37/84 (44%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K    ++ DTP+ +  K      S   Y+  +E+ K KG+ +  D   ++  K +++  S
Sbjct: 2488 KTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIAS 2547

Query: 119  NIKYHEEFEKSRMGPSGGEGMEPE 142
              KY E F K      G   +E +
Sbjct: 2548 EYKYKEGFRKQLGHHIGARNIEDD 2571



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISN 119
           Q +    DTPE  R+K+  +  S+V+Y+ + +  K     V     +++  KK   Q+S 
Sbjct: 111 QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAK-TICHVDEKAKDIEHAKKVSQQVSK 169

Query: 120 IKYHEEFEKSR 130
           + Y + +E ++
Sbjct: 170 VLYKQNWEDTK 180



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 49   KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108
            K+ Y  A   +  F  + D P+ +     +++QS   YK+ +E +K K +    D   + 
Sbjct: 1577 KEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK-YHTPLDMVSVT 1635

Query: 109  RIKKTQDQISNIKYHEEFEKSRMGP 133
              KK+Q+  +N  Y + +    + P
Sbjct: 1636 AAKKSQEVATNANYRQSYHHYTLLP 1660



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 10/88 (11%)

Query: 39   LNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGF 98
            LN K Y+          H     FT + D+P  ++ KQ ++  S + YK + E  K K +
Sbjct: 1223 LNEKKYR---------QHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHK-Y 1272

Query: 99   SVVADTPELQRIKKTQDQISNIKYHEEF 126
            ++  D P+  + K     IS++ Y  ++
Sbjct: 1273 TMSPDLPQFLQAKCNAYNISDVCYKRDW 1300



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 17/68 (25%), Positives = 39/68 (57%), Gaps = 1/68 (1%)

Query: 57   YPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ 116
            +P   +T + D  + ++ ++  +LQS   YK + E  +G G+ V   + E++++K+  + 
Sbjct: 3598 HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGW-VPIGSVEVEKVKRAGEI 3656

Query: 117  ISNIKYHE 124
            +S+ KY +
Sbjct: 3657 LSDRKYRQ 3664



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 15/81 (18%), Positives = 41/81 (50%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            + +  D P+ ++ K  +   S+  YK + +    KG+ +  D   ++  K  +   S+++
Sbjct: 1028 YNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQ 1087

Query: 122  YHEEFEKSRMGPSGGEGMEPE 142
            Y +++EK++    G + ++ +
Sbjct: 1088 YKKDYEKAKGKMVGFQSLQDD 1108



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 75   KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            K    + S  +YKE +EK KGK  GF  + D P+L          S+ +Y + +E S+
Sbjct: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASK 1622



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 49/232 (21%), Positives = 84/232 (36%), Gaps = 32/232 (13%)

Query: 56   HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115
            H  K  FT   DT E    K       +  Y E++ K+K     V+ DTP++   +  Q 
Sbjct: 1719 HPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDK-TTIHVMPDTPDILLSRVNQI 1777

Query: 116  QISNIKYHEEFEKSRMGPSGGEGMEPE---------RRDSQDGSSYRRPLEQQQPHHI-- 164
             +S+  Y   +E+ +     G  + P+          RD      Y++  EQ +  HI  
Sbjct: 1778 TMSDKLYKAGWEEEK---KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGF 1834

Query: 165  ------PTSAPVYQQPQQQPVAQSYGGYK----------EPAAPVSIQRSAPGGGGKRYR 208
                  P      Q  + Q   +   GY+          +  + V+ ++S        YR
Sbjct: 1835 RSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYR 1894

Query: 209  AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEA 260
             V        D +SF+    ++ +Q  D+ +     +     G LP   +EA
Sbjct: 1895 NVIHTYNMLPDAMSFELAKNMMQIQS-DNQYKADYADFMKGIGWLPLGSLEA 1945



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 40/171 (23%), Positives = 67/171 (39%), Gaps = 14/171 (8%)

Query: 27  KACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVA--DTPENLRLKQQSELQSQV 84
           K+  +CET K  L+ +  K + +  Y + +        V   + P +    + +   S  
Sbjct: 645 KSMNYCETPKYQLDTQ-LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDK 703

Query: 85  RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144
            YK E+E++KGK +     T E + IKK  DQ  +  Y    +K++          P   
Sbjct: 704 SYKAEYEEDKGKCYFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTKFTAVTD---SPVLL 759

Query: 145 DSQDGSSYRRPLEQQQPH-------HIPTSAPVYQQPQQQPVAQSYGGYKE 188
            +Q  +     L  +  H       HIP  AP + Q +      S   YK+
Sbjct: 760 QAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQ 810



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 1/69 (1%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            +T + D  + ++ K+  ELQS+  YK + E  +G G+S +    E ++ K+  + IS  K
Sbjct: 2388 WTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSL-EAEKNKRASEIISEKK 2446

Query: 122  YHEEFEKSR 130
            Y +  ++++
Sbjct: 2447 YRQPPDRNK 2455



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 25/112 (22%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIK----KTQ 114
            +  FT + D  + +  K  ++ +S   Y+E ++K+K +   ++ DTP++   K     T 
Sbjct: 2453 RNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQ-IHIMPDTPDIVLAKANLINTS 2511

Query: 115  DQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGS--SYRRPLEQQQPHHI 164
            D++  + Y E   K    P     ++  +   +  S   Y+    +Q  HHI
Sbjct: 2512 DKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHI 2563



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            + D P+ +     +++QS   YK++FEK K K FS   D   +   KK Q  +S++ Y  
Sbjct: 2811 IRDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYKN 2869

Query: 125  EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157
               +    P   + +   +  D Q  + Y+  L+
Sbjct: 2870 YLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQ 2903



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            + D P+ +     +++QS   YK++FEK K K FS   D   +   KK Q  +S++ Y  
Sbjct: 2568 IEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYKN 2626

Query: 125  EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157
               +    P   + +   +  D Q  + Y+  L+
Sbjct: 2627 YLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQ 2660



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 10/99 (10%)

Query: 33   ETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92
            E CK    + + K Y + P       +  FT V D+ E +  K  +   ++  Y E ++K
Sbjct: 2919 EKCKRATEILSDKIYRQPP------DRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDK 2972

Query: 93   NKGKGFSVVADTPELQRIKKTQDQISNIKY---HEEFEK 128
            +K +   ++ DTPE+   ++ +   S   Y   +EE +K
Sbjct: 2973 DKTQ-IHIMPDTPEIMLARQNKINYSETLYKLANEEAKK 3010



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            + D P+ +     +++QS   YK++FEK K K FS   D   +   KK Q  +S++ Y  
Sbjct: 3054 IEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYKN 3112

Query: 125  EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157
               +    P   + +   +  D Q  + Y+  L+
Sbjct: 3113 YLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQ 3146



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
            V D P   R  +  +L     Y+  +EKNK K   +V D  E+   K +Q ++S I Y
Sbjct: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMK-IHIVPDMVEMVTAKDSQKKVSEIDY 4813



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 65  VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
           + D P+ L   + ++ QS   YKE +EK K K  +   +TP+ Q +       S  +Y +
Sbjct: 614 INDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMN-YCETPKYQ-LDTQLKNFSEARYKD 671

Query: 125 EFEKSRMGPSGGEGMEP 141
            + K  +G   G   +P
Sbjct: 672 LYVKDVLGHYVGSMEDP 688



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 18/76 (23%), Positives = 32/76 (42%), Gaps = 1/76 (1%)

Query: 49   KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108
            K+ Y  +      F  + D P+ +     ++LQS   YK+ +E  K   +    D   + 
Sbjct: 1333 KEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK-TSYHTPGDMVSIT 1391

Query: 109  RIKKTQDQISNIKYHE 124
              K  QD  +N+ Y +
Sbjct: 1392 AAKMAQDVATNVNYKQ 1407



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 16/70 (22%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 61   SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120
            +FT V D  + +  KQ  E+   ++Y++++   K K    + +TP L   ++    +   
Sbjct: 4155 NFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK--YTLTETPLLHTAQEAARILDQY 4212

Query: 121  KYHEEFEKSR 130
             Y E +E+ +
Sbjct: 4213 LYKEGWERQK 4222



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 6/98 (6%)

Query: 38   TLNMKNYKGYEKKPYCNA--HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95
            T N+KN   Y    Y  A       S+ + + T      K Q  L S ++Y+EE+EK K 
Sbjct: 4692 TRNLKNL--YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKA 4749

Query: 96   KGF--SVVADTPELQRIKKTQDQISNIKYHEEFEKSRM 131
                   V D P   R  +      +  Y   +EK++M
Sbjct: 4750 LYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKM 4787



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            F  + D P+ +   Q +++QS   YK+ +E  K   +   AD   +   K  Q  I+N  
Sbjct: 2078 FRSLEDDPKLVHSMQVAKMQSDREYKKNYENTK-TSYHTPADMLSVTAAKDAQANITNTN 2136

Query: 122  YHEEFEK 128
            Y     K
Sbjct: 2137 YKHLIHK 2143



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 57   YPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ 116
            +P   +  + D  + +  ++  +LQS   YK + E  KG G+ V  D+ E+ R K+  + 
Sbjct: 3355 HPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGW-VPIDSLEVVRAKRAGEL 3413

Query: 117  ISNIKYHEEFE 127
            +S+  Y +  E
Sbjct: 3414 LSDTIYRQRPE 3424



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 79   ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            +LQS   YK    +    G+ +  DTP  + IK T+   S  KY E +E ++
Sbjct: 4943 KLQSSNLYKTSL-RTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTK 4993



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 16/41 (39%), Positives = 21/41 (51%)

Query: 104 TPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144
           TP +   +K QD  S  KY E+FEK++  P       PE R
Sbjct: 83  TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELR 123



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124
            V D P+ +     +++QS   YK++FEK K + +S   D   +   KK Q  +S++ Y  
Sbjct: 3297 VHDDPKIMWSLHIAKVQSDREYKKDFEKYKTR-YSSPVDMLGIVLAKKCQTLVSDVDYKH 3355

Query: 125  EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157
               +    P   + +   +  D Q  + Y+  LE
Sbjct: 3356 PLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLE 3389



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 15/84 (17%)

Query: 32   CETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91
            C+T    ++ +NY                 +T + D  + ++ K+  +LQS   YK + E
Sbjct: 3830 CQTLVTDIDYRNYL--------------HEWTCMPDQNDIIQAKKAYDLQSDALYKADLE 3875

Query: 92   KNKGKGFSVVADTPELQRIKKTQD 115
              +G G+ +   +PE+ R+K  Q+
Sbjct: 3876 WLRGIGW-MPQGSPEVLRVKNAQN 3898



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K  +T+  +TP     ++ + +  Q  YKE +E+ K  G+ +  D           D  S
Sbjct: 4188 KSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQS 4246

Query: 119  NIKYHEEFEKSR 130
             +KY  E  K +
Sbjct: 4247 ELKYKAEHVKQK 4258



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 30/130 (23%), Positives = 49/130 (37%), Gaps = 4/130 (3%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            +T + D  + ++ K+  ELQS   YK + E  +G G+ +  D+  +   K   D  S  K
Sbjct: 4088 WTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGW-MPNDSVSVNHAKHAADIFSEKK 4146

Query: 122  YHEEFEKSRMGPSGGEGMEPERRDS---QDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQP 178
            Y  + E     P          + S    D   YR+     +  +  T  P+    Q+  
Sbjct: 4147 YRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLHTAQEAA 4206

Query: 179  VAQSYGGYKE 188
                   YKE
Sbjct: 4207 RILDQYLYKE 4216



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 15/58 (25%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 75   KQQSELQSQVRYKEEFEKNKGKGFS--VVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
            K    + S+++YKE +EK KG   +  V+ + P +      Q   S + Y + +E ++
Sbjct: 4484 KHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTK 4541



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 14/110 (12%)

Query: 25   WHKAC-------FHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQ 77
            W K C          E  K   ++ N K Y + P          FT + D P  ++ K  
Sbjct: 955  WMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHP------DTLKFTSIEDAPITVQSKIN 1008

Query: 78   SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
               +S + YK + E+   K +++  D P+  + K     IS   Y  + +
Sbjct: 1009 QAQRSDIAYKAKGEEIIHK-YNLPPDLPQFIQAKVNAYNISENMYKADLK 1057


>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
          Length = 1014

 Score =  120 bits (302), Expect = 9e-28
 Identities = 92/285 (32%), Positives = 128/285 (44%), Gaps = 60/285 (21%)

Query: 34   TCKMTLNMKNYKGYEKKPYCNAHYP-KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92
            T +M    KN +      Y   H   K   +++ DTP    +K+     S V+Y E+FEK
Sbjct: 732  TPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEK 791

Query: 93   NKGKGFS----------------VVADT------PELQRIKKTQDQISNIK--------- 121
             KG+GF+                VV+D       P +  + +    I ++K         
Sbjct: 792  TKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSI 851

Query: 122  ------------------------YHEEFEKSRMGPSGGEGMEPERRD-SQDGSSYRRPL 156
                                    Y   + +S    + G G+  +R + S+   S+    
Sbjct: 852  FDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCS 911

Query: 157  EQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAA 216
            E  +P      APV     QQ  +Q YG Y    +  S++        + YRA+YDYSA 
Sbjct: 912  EVTRPSD--EGAPVLPGAYQQSHSQGYG-YMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQ 968

Query: 217  DEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
            DEDEVSF+DGD IVNVQ IDDGWMYGTV+RTG TGMLPANY+E +
Sbjct: 969  DEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 1013



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 33/69 (47%), Positives = 40/69 (57%)

Query: 66  ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
           AD  E+L  K  + LQSQV+YKEE+EKNKGK      +TP  Q  K+ Q   S   Y E+
Sbjct: 319 ADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKED 378

Query: 126 FEKSRMGPS 134
           FEK   G S
Sbjct: 379 FEKEIKGRS 387



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 34/95 (35%), Positives = 57/95 (60%), Gaps = 8/95 (8%)

Query: 49  KKPYCNAHYPKQ--SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106
           +K   N +Y  Q    T ++ TPE  R+K+  E  S V+Y ++ ++ KG+  S++ DTP 
Sbjct: 711 QKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRP-SLILDTPA 769

Query: 107 LQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEP 141
           ++ +K+ Q+ IS +KYHE+FEK++     G G  P
Sbjct: 770 MRHVKEAQNHISMVKYHEDFEKTK-----GRGFTP 799



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 28/67 (41%), Positives = 43/67 (64%), Gaps = 5/67 (7%)

Query: 61  SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120
           +++ +ADTPE  R+K   +  S V YK+E     G G + V D+PE++R+KK Q  IS++
Sbjct: 570 NYSTIADTPEIQRIKTTQQNISAVFYKKEV----GAG-TAVKDSPEIERVKKNQQNISSV 624

Query: 121 KYHEEFE 127
           KY EE +
Sbjct: 625 KYKEEIK 631



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 27/67 (40%), Positives = 42/67 (62%), Gaps = 5/67 (7%)

Query: 63  TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
           T V D+PE  R+K+  +  S V+YKEE      K  + ++D PEL+R+K+ Q  ISN++Y
Sbjct: 603 TAVKDSPEIERVKKNQQNISSVKYKEEI-----KHATAISDPPELKRVKENQKNISNLQY 657

Query: 123 HEEFEKS 129
            E+  K+
Sbjct: 658 KEQNYKA 664



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 27/63 (42%), Positives = 38/63 (60%), Gaps = 1/63 (1%)

Query: 67  DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
           DT +  R K+ SE+ SQ +YK++ E   KGKG  V  D P++ R K+T +  S  KY +E
Sbjct: 504 DTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDE 563

Query: 126 FEK 128
            EK
Sbjct: 564 AEK 566



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 33/114 (28%), Positives = 61/114 (53%), Gaps = 8/114 (7%)

Query: 49  KKPYCNAHYPKQSF--TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106
           +K   N  Y +Q++  T V+ TPE  R+++  E  S V+YK E ++      + ++D PE
Sbjct: 649 QKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGELQRG-----TAISDPPE 703

Query: 107 LQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQ 160
           L+R K+ Q  ISN+ Y  +  ++       E ME  +++ ++ SS +   + +Q
Sbjct: 704 LKRAKENQKNISNVYYRGQLGRATTLSVTPE-MERVKKNQENISSVKYTQDHKQ 756



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 22/66 (33%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 63  TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
           T ++D PE  R+K+  +  S ++YKE+  K      + V+ TPE++R+++ Q+Q+S +KY
Sbjct: 634 TAISDPPELKRVKENQKNISNLQYKEQNYKA-----TPVSMTPEIERVRRNQEQLSAVKY 688

Query: 123 HEEFEK 128
             E ++
Sbjct: 689 KGELQR 694



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 67  DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
           DT E    K+ +E+ S+  YK + E   KGKG  V  DT ++QR KK  +  S  +Y ++
Sbjct: 467 DTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKD 526

Query: 126 FEKSRMG 132
            E    G
Sbjct: 527 LENEIKG 533



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 8/100 (8%)

Query: 68  TPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126
           TPE L +K  + L  +  YK++ E   KGKG  + ++  ++QR K+  +  S  +Y ++ 
Sbjct: 394 TPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDL 453

Query: 127 EKSRMGPSGGEG-----MEPERRDSQDGS--SYRRPLEQQ 159
           E    G     G     M+  ++ ++  S   Y+R LE +
Sbjct: 454 ESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETE 493



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 78  SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
           +EL S +RYKEEF+K+K K  + V D+P L  +K     IS  KY
Sbjct: 46  TELISDIRYKEEFKKSKDK-CTFVTDSPMLNHVKNIGAFISEAKY 89



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)

Query: 73  RLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM 131
           R K+ SE+ S+  YK++ E   KGKG     DT E+Q  KK  +  S   Y  + E    
Sbjct: 436 RAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIK 495

Query: 132 G 132
           G
Sbjct: 496 G 496



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 22/98 (22%), Positives = 48/98 (48%), Gaps = 6/98 (6%)

Query: 31  HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90
           H +     ++   YKG  K    N+ Y +   T+     +++   + ++LQS+V YK++ 
Sbjct: 76  HVKNIGAFISEAKYKGTIKADLSNSLYKRMPATI-----DSVFAGEVTQLQSEVAYKQKH 130

Query: 91  EKNKG-KGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
           +  KG   ++ + + PE++   +     SNI Y ++ +
Sbjct: 131 DAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQ 168



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 12/69 (17%)

Query: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
           F  + D  E  ++ ++   + QV YK             V +   ++  +K  + IS+I+
Sbjct: 6   FEDIKDETEEEKIGEEENEEDQVFYKP------------VIEDLSMELARKCTELISDIR 53

Query: 122 YHEEFEKSR 130
           Y EEF+KS+
Sbjct: 54  YKEEFKKSK 62



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 15/149 (10%)

Query: 54  NAHYPKQSFTM-----VADTPENLRLKQQSELQSQVRYKEEFE---KNKGKGFSVVADTP 105
           NA Y K    M     V   P+     + S+L SQ++YKE+F+   K+K   ++ + ++ 
Sbjct: 194 NAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPL-ESA 252

Query: 106 ELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGM-----EPERRDSQDGSSYRRPLEQQQ 160
             ++ +      SN+KY ++ +      S    +       +      G  Y++  E+ +
Sbjct: 253 SFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENK 312

Query: 161 -PHHIPTSAPVYQQPQQQPVAQSYGGYKE 188
             +H    A  +   +   V QS   YKE
Sbjct: 313 GMYHFDADAVEHLHHKGNAVLQSQVKYKE 341


>gi|46049092 nebulin-related anchoring protein isoform C [Homo
          sapiens]
          Length = 1695

 Score =  105 bits (263), Expect = 3e-23
 Identities = 46/91 (50%), Positives = 64/91 (70%), Gaps = 1/91 (1%)

Query: 5  CARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFT 63
          C+RCG  VYP EK++C+D+ WHKACFHCE CKM L++ N+  ++KKPYC+AH PK  +FT
Sbjct: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65

Query: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNK 94
           V  TP NL ++   E  S +  +E+ E+ K
Sbjct: 66 SVYHTPLNLNVRTFPEAISGIHDQEDGEQCK 96



 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%)

Query: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
           F+ V DTPE LR K  ++LQS VRY E++E+ +GKG      TP  Q  K+  +  S+++
Sbjct: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263

Query: 122 YHEEFEKSRMGPS----GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQ 177
           YH++++K   G +    G EG+       Q G  Y    E+ + H    S P    P  Q
Sbjct: 264 YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYP---EEYEEHRGKGSFPAMITPAYQ 320

Query: 178 PVAQSY 183
              +++
Sbjct: 321 NAKKAH 326



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 9/93 (9%)

Query: 39  LNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG 97
           L+  NY+  YEK         K ++T+  D P+ ++ K  ++L S+V+YKE +EK KGKG
Sbjct: 472 LSHVNYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKG 523

Query: 98  FSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
           F +  D   L   K + +  SNIKY EE+EK++
Sbjct: 524 FEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 9/140 (6%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K  +T  AD PE L  K  +   S+ RYKE + K +  G+ +  D    Q  K + + IS
Sbjct: 967  KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1026

Query: 119  NIKYHEEFEKSRMGPSGGEGMEPE--------RRDSQDGSSYRRPLEQQQPH-HIPTSAP 169
            + KY E FEK +    G   +E +            Q   +Y++  E  +   H+P    
Sbjct: 1027 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1086

Query: 170  VYQQPQQQPVAQSYGGYKEP 189
                 ++     S   YK P
Sbjct: 1087 ALVHAKKAQTLASNQDYKHP 1106



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 6/82 (7%)

Query: 59  KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
           K  ++ V DTP+ ++ K  ++  S V Y+ ++EKNK   +++  D P+L + K      S
Sbjct: 450 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 508

Query: 119 NIKYHEEFEKSRMGPSGGEGME 140
            +KY E +EK++     G+G E
Sbjct: 509 EVKYKEGWEKTK-----GKGFE 525



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%)

Query: 68  TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
           TP   R K+ ++L SQV YK   ++   + FS V DTPEL R K      S+++Y E++E
Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233

Query: 128 KSR 130
           + R
Sbjct: 234 QQR 236



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 22/69 (31%), Positives = 36/69 (52%)

Query: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
           +T+  D P  L+ +  +   S+  YK  +E  K KGF +  D+      K  +D  S +K
Sbjct: 727 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 786

Query: 122 YHEEFEKSR 130
           Y E++E+SR
Sbjct: 787 YKEDYERSR 795



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%)

Query: 36  KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95
           K+   +K  +G+EK          + F M  D    L  K   EL S ++YKEE+EK KG
Sbjct: 505 KLFSEVKYKEGWEKTK-------GKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 557

Query: 96  KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
           K     AD+  L  ++  +   S ++Y + FE+S+
Sbjct: 558 KAMG-TADSRLLHSLQIAK-MSSEVEYKKGFEESK 590



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 18/45 (40%), Positives = 27/45 (60%)

Query: 86  YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
           Y EE+E+++GKG      TP  Q  KK  +  S+IKY ++F K +
Sbjct: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMK 342



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            +  +TM    PE +R K  +   S  RYKE +   + +G+ +  +    Q  + + D  S
Sbjct: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269

Query: 119  NIKYHEEFEKSRMGPSGGEGMEPERR--------DSQDGSSYRR-PLEQQQPHHIP 165
            +  Y  +F K R    G + +  + R          Q    YRR     Q   H+P
Sbjct: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1325



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 56  HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG--FSVVA-DTPELQRIKK 112
           H  K SF  +  TP     K+  EL S ++Y+++F K KG     S+ A D   L++ + 
Sbjct: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363

Query: 113 TQDQISNIKYHEEFEKSRMGPSGGEGME 140
               +S  KY E ++    G   G GM+
Sbjct: 364 VNKLVSENKYKENYQNHMRGRYEGVGMD 391



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 79   ELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM---GP 133
            E+ S  RYKE F +++G   G+  V D P ++         S+ +Y ++F KSR      
Sbjct: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568

Query: 134  SGGEGMEPERRDSQDGSS--YRRPLEQ 158
            +   G+   +R  Q  S   YR+PL Q
Sbjct: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQ 1595



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 4/60 (6%)

Query: 69   PENLRL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
            PE+L++   K+   LQS++RYK +    KG G+ +   +P+++  KK  + IS  KY ++
Sbjct: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1415



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117
           + F +  D+   L  K + +L S+V+YKE++E+++GK  G   V    ++    +     
Sbjct: 761 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 820

Query: 118 SNIKYHEEFEKSR 130
           S ++Y + FE ++
Sbjct: 821 SELEYKKGFEDTK 833



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 56   HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115
            H     FT + DTPE ++ +          Y+E+ E  K   ++  AD PE+   K    
Sbjct: 929  HPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-YTPTADLPEVLLAKLNAM 987

Query: 116  QISNIKYHEEFEKSRMG 132
             IS  +Y E + K R G
Sbjct: 988  NISETRYKESWSKLRDG 1004



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            +  V D P          LQS   YK++F K++ + F    D P L + K++Q   S++ 
Sbjct: 1530 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1588

Query: 122  YHEEFEKSRMGP 133
            Y +   +    P
Sbjct: 1589 YRQPLPQPTCDP 1600



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)

Query: 69  PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HEE 125
           PE +R+ +  +   +  Y E++E+ +GKG      TP  QR KK     S ++Y   H+E
Sbjct: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 38/182 (20%), Positives = 77/182 (42%), Gaps = 28/182 (15%)

Query: 33  ETCKMTLNMKNYKGYEKKP--------YCNAHYPKQSFTMVADT------------PENL 72
           +  KM+  ++  KG+E+            N  + K++ T+ +D             PE++
Sbjct: 572 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 631

Query: 73  RL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129
           +    K+   LQS+++YK +    KG G+ +   +  L++ KK    +S   Y +  ++ 
Sbjct: 632 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 690

Query: 130 RM-GPSGGEGMEPERR--DSQDGSSYRRPLEQQ-QPHHIPTSAPVYQQPQQQPVAQSYGG 185
           +    +    ME  ++  + Q G +Y+   EQ    + I    P++ Q +      S   
Sbjct: 691 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 750

Query: 186 YK 187
           YK
Sbjct: 751 YK 752



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            +T V DTP  L  K  +++ ++  YK   E  + + +++    PE  R K     +S+ +
Sbjct: 1178 YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHE-YTMTLGLPEFIRAKTNAANLSDAR 1236

Query: 122  YHEEFEKSR 130
            Y E +   R
Sbjct: 1237 YKESWRNLR 1245



 Score = 28.1 bits (61), Expect = 8.1
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 76  QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
           Q S+LQS++ YK+ FE  K +   V  D   L   +K Q   +++ Y
Sbjct: 815 QMSKLQSELEYKKGFEDTKSQ-CHVSLDMVHLVHARKAQHLATDVGY 860


>gi|46049105 nebulin-related anchoring protein isoform S [Homo
          sapiens]
          Length = 1730

 Score =  105 bits (263), Expect = 3e-23
 Identities = 46/91 (50%), Positives = 64/91 (70%), Gaps = 1/91 (1%)

Query: 5  CARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFT 63
          C+RCG  VYP EK++C+D+ WHKACFHCE CKM L++ N+  ++KKPYC+AH PK  +FT
Sbjct: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65

Query: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNK 94
           V  TP NL ++   E  S +  +E+ E+ K
Sbjct: 66 SVYHTPLNLNVRTFPEAISGIHDQEDGEQCK 96



 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%)

Query: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
           F+ V DTPE LR K  ++LQS VRY E++E+ +GKG      TP  Q  K+  +  S+++
Sbjct: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263

Query: 122 YHEEFEKSRMGPS----GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQ 177
           YH++++K   G +    G EG+       Q G  Y    E+ + H    S P    P  Q
Sbjct: 264 YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYP---EEYEEHRGKGSFPAMITPAYQ 320

Query: 178 PVAQSY 183
              +++
Sbjct: 321 NAKKAH 326



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 9/93 (9%)

Query: 39  LNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG 97
           L+  NY+  YEK         K ++T+  D P+ ++ K  ++L S+V+YKE +EK KGKG
Sbjct: 507 LSHVNYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKG 558

Query: 98  FSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
           F +  D   L   K + +  SNIKY EE+EK++
Sbjct: 559 FEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591



 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 9/140 (6%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            K  +T  AD PE L  K  +   S+ RYKE + K +  G+ +  D    Q  K + + IS
Sbjct: 1002 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061

Query: 119  NIKYHEEFEKSRMGPSGGEGMEPE--------RRDSQDGSSYRRPLEQQQPH-HIPTSAP 169
            + KY E FEK +    G   +E +            Q   +Y++  E  +   H+P    
Sbjct: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1121

Query: 170  VYQQPQQQPVAQSYGGYKEP 189
                 ++     S   YK P
Sbjct: 1122 ALVHAKKAQTLASNQDYKHP 1141



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 6/82 (7%)

Query: 59  KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
           K  ++ V DTP+ ++ K  ++  S V Y+ ++EKNK   +++  D P+L + K      S
Sbjct: 485 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 543

Query: 119 NIKYHEEFEKSRMGPSGGEGME 140
            +KY E +EK++     G+G E
Sbjct: 544 EVKYKEGWEKTK-----GKGFE 560



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%)

Query: 68  TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127
           TP   R K+ ++L SQV YK   ++   + FS V DTPEL R K      S+++Y E++E
Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233

Query: 128 KSR 130
           + R
Sbjct: 234 QQR 236



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 22/69 (31%), Positives = 36/69 (52%)

Query: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
           +T+  D P  L+ +  +   S+  YK  +E  K KGF +  D+      K  +D  S +K
Sbjct: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821

Query: 122 YHEEFEKSR 130
           Y E++E+SR
Sbjct: 822 YKEDYERSR 830



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%)

Query: 36  KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95
           K+   +K  +G+EK          + F M  D    L  K   EL S ++YKEE+EK KG
Sbjct: 540 KLFSEVKYKEGWEKTK-------GKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 592

Query: 96  KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
           K     AD+  L  ++  +   S ++Y + FE+S+
Sbjct: 593 KAMG-TADSRLLHSLQIAK-MSSEVEYKKGFEESK 625



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 18/45 (40%), Positives = 27/45 (60%)

Query: 86  YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130
           Y EE+E+++GKG      TP  Q  KK  +  S+IKY ++F K +
Sbjct: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMK 342



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 4/74 (5%)

Query: 70  ENLRLKQQ---SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126
           +NL LKQ    ++L S+V YK++ E ++G   +   +TP+ + + K     S+ KY E +
Sbjct: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINY-CETPQFRNVSKISKFTSDNKYKENY 412

Query: 127 EKSRMGPSGGEGME 140
           +    G   G GM+
Sbjct: 413 QNHMRGRYEGVGMD 426



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%)

Query: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118
            +  +TM    PE +R K  +   S  RYKE +   + +G+ +  +    Q  + + D  S
Sbjct: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304

Query: 119  NIKYHEEFEKSRMGPSGGEGMEPERR--------DSQDGSSYRR-PLEQQQPHHIP 165
            +  Y  +F K R    G + +  + R          Q    YRR     Q   H+P
Sbjct: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1360



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 79   ELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM---GP 133
            E+ S  RYKE F +++G   G+  V D P ++         S+ +Y ++F KSR      
Sbjct: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603

Query: 134  SGGEGMEPERRDSQDGSS--YRRPLEQ 158
            +   G+   +R  Q  S   YR+PL Q
Sbjct: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQ 1630



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 4/78 (5%)

Query: 56  HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG--FSVVA-DTPELQRIKK 112
           H  K SF  +  TP     K+  EL S ++Y+++F K KG     S+ A D   L++ + 
Sbjct: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363

Query: 113 TQDQISNIKYHEEFEKSR 130
               +S ++Y ++ E SR
Sbjct: 364 VNKLVSEVEYKKDLESSR 381



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 4/60 (6%)

Query: 69   PENLRL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
            PE+L++   K+   LQS++RYK +    KG G+ +   +P+++  KK  + IS  KY ++
Sbjct: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1450



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117
           + F +  D+   L  K + +L S+V+YKE++E+++GK  G   V    ++    +     
Sbjct: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855

Query: 118 SNIKYHEEFEKSR 130
           S ++Y + FE ++
Sbjct: 856 SELEYKKGFEDTK 868



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 56   HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115
            H     FT + DTPE ++ +          Y+E+ E  K   ++  AD PE+   K    
Sbjct: 964  HPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-YTPTADLPEVLLAKLNAM 1022

Query: 116  QISNIKYHEEFEKSRMG 132
             IS  +Y E + K R G
Sbjct: 1023 NISETRYKESWSKLRDG 1039



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            +  V D P          LQS   YK++F K++ + F    D P L + K++Q   S++ 
Sbjct: 1565 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1623

Query: 122  YHEEFEKSRMGP 133
            Y +   +    P
Sbjct: 1624 YRQPLPQPTCDP 1635



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)

Query: 69  PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HEE 125
           PE +R+ +  +   +  Y E++E+ +GKG      TP  QR KK     S ++Y   H+E
Sbjct: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 38/182 (20%), Positives = 77/182 (42%), Gaps = 28/182 (15%)

Query: 33  ETCKMTLNMKNYKGYEKKP--------YCNAHYPKQSFTMVADT------------PENL 72
           +  KM+  ++  KG+E+            N  + K++ T+ +D             PE++
Sbjct: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 666

Query: 73  RL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129
           +    K+   LQS+++YK +    KG G+ +   +  L++ KK    +S   Y +  ++ 
Sbjct: 667 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725

Query: 130 RM-GPSGGEGMEPERR--DSQDGSSYRRPLEQQ-QPHHIPTSAPVYQQPQQQPVAQSYGG 185
           +    +    ME  ++  + Q G +Y+   EQ    + I    P++ Q +      S   
Sbjct: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785

Query: 186 YK 187
           YK
Sbjct: 786 YK 787



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
            +T V DTP  L  K  +++ ++  YK   E  + + +++    PE  R K     +S+ +
Sbjct: 1213 YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHE-YTMTLGLPEFIRAKTNAANLSDAR 1271

Query: 122  YHEEFEKSR 130
            Y E +   R
Sbjct: 1272 YKESWRNLR 1280



 Score = 28.1 bits (61), Expect = 8.1
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)

Query: 76  QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122
           Q S+LQS++ YK+ FE  K +   V  D   L   +K Q   +++ Y
Sbjct: 850 QMSKLQSELEYKKGFEDTKSQ-CHVSLDMVHLVHARKAQHLATDVGY 895


>gi|20357552 cortactin isoform a [Homo sapiens]
          Length = 550

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 57/203 (28%), Positives = 88/203 (43%), Gaps = 33/203 (16%)

Query: 66  ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
           A+     R+ ++ + Q + R K E +         V+  P+      T++++ +   +E+
Sbjct: 369 AEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQ-----PTEERLPSSPVYED 423

Query: 126 F-----EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQ---PQQQ 177
                 E S  GP  G   EPE   S + + YR    QQ   +   +  VY+    P   
Sbjct: 424 AASFKAELSYRGPVSGT--EPEPVYSMEAADYREASSQQGLAY--ATEAVYESAEAPGHY 479

Query: 178 PVAQS-YGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQID 236
           P   S Y  Y+      ++             A+YDY AA +DE+SF   D I N++ ID
Sbjct: 480 PAEDSTYDEYENDLGITAV-------------ALYDYQAAGDDEISFDPDDIITNIEMID 526

Query: 237 DGWMYGTVERTGDTGMLPANYVE 259
           DGW  G  +  G  G+ PANYVE
Sbjct: 527 DGWWRGVCK--GRYGLFPANYVE 547


>gi|20357556 cortactin isoform b [Homo sapiens]
          Length = 513

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 57/203 (28%), Positives = 88/203 (43%), Gaps = 33/203 (16%)

Query: 66  ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125
           A+     R+ ++ + Q + R K E +         V+  P+      T++++ +   +E+
Sbjct: 332 AEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQ-----PTEERLPSSPVYED 386

Query: 126 F-----EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQ---PQQQ 177
                 E S  GP  G   EPE   S + + YR    QQ   +   +  VY+    P   
Sbjct: 387 AASFKAELSYRGPVSGT--EPEPVYSMEAADYREASSQQGLAY--ATEAVYESAEAPGHY 442

Query: 178 PVAQS-YGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQID 236
           P   S Y  Y+      ++             A+YDY AA +DE+SF   D I N++ ID
Sbjct: 443 PAEDSTYDEYENDLGITAV-------------ALYDYQAAGDDEISFDPDDIITNIEMID 489

Query: 237 DGWMYGTVERTGDTGMLPANYVE 259
           DGW  G  +  G  G+ PANYVE
Sbjct: 490 DGWWRGVCK--GRYGLFPANYVE 510


>gi|21361670 drebrin-like isoform a [Homo sapiens]
          Length = 431

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 61/207 (29%), Positives = 86/207 (41%), Gaps = 21/207 (10%)

Query: 68  TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF- 126
           +P++   +QQ E+ S+ R ++E   +  + F           I   Q      K    F 
Sbjct: 232 SPQSRTWEQQQEVVSRNRNEQESAVHPREIFKQKERAMSTTSISSPQPG----KLRSPFL 287

Query: 127 EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT-----SAPVYQQPQQQ---- 177
           +K    P    G EP    S+  +    P E+  P   P         VY++P +Q    
Sbjct: 288 QKQLTQPETHFGREPAAAISRPRADL--PAEEPAPSTPPCLVQAEEEAVYEEPPEQETFY 345

Query: 178 ---PVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQ 234
              P+ Q  G   E      IQ     G G   RA+YDY AAD+ E+SF   + I  ++ 
Sbjct: 346 EQPPLVQQQGAGSEHIDH-HIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEV 404

Query: 235 IDDGWMYGTVERTGDTGMLPANYVEAI 261
           ID+GW  G     G  GM PANYVE I
Sbjct: 405 IDEGWWRG-YGPDGHFGMFPANYVELI 430


>gi|62198235 drebrin-like isoform b [Homo sapiens]
          Length = 430

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 27/199 (13%)

Query: 75  KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPS 134
           + ++E +S V  +E F++ +    +    +P+  +++               +K    P 
Sbjct: 246 RNRNEQESAVHPREIFKQKERAMSTTSISSPQPGKLRSPF-----------LQKQLTQPE 294

Query: 135 GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT-----SAPVYQQPQQQ-------PVAQS 182
              G EP    S+  +    P E+  P   P         VY++P +Q       P+ Q 
Sbjct: 295 THFGREPAAAISRPRADL--PAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPLVQQ 352

Query: 183 YGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYG 242
            G   E      IQ     G G   RA+YDY AAD+ E+SF   + I  ++ ID+GW  G
Sbjct: 353 QGAGSEHIDH-HIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG 411

Query: 243 TVERTGDTGMLPANYVEAI 261
                G  GM PANYVE I
Sbjct: 412 -YGPDGHFGMFPANYVELI 429


>gi|171906575 drebrin-like isoform c [Homo sapiens]
          Length = 439

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 49/147 (33%), Positives = 64/147 (43%), Gaps = 16/147 (10%)

Query: 127 EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT-----SAPVYQQPQQQ---- 177
           +K    P    G EP    S+  +    P E+  P   P         VY++P +Q    
Sbjct: 296 QKQLTQPETHFGREPAAAISRPRADL--PAEEPAPSTPPCLVQAEEEAVYEEPPEQETFY 353

Query: 178 ---PVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQ 234
              P+ Q  G   E      IQ     G G   RA+YDY AAD+ E+SF   + I  ++ 
Sbjct: 354 EQPPLVQQQGAGSEHIDH-HIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEV 412

Query: 235 IDDGWMYGTVERTGDTGMLPANYVEAI 261
           ID+GW  G     G  GM PANYVE I
Sbjct: 413 IDEGWWRG-YGPDGHFGMFPANYVELI 438


>gi|19224660 protein kinase C and casein kinase substrate in neurons
           3 [Homo sapiens]
          Length = 424

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 52/194 (26%), Positives = 93/194 (47%), Gaps = 22/194 (11%)

Query: 72  LRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM 131
           L L Q  +L S  ++  E  ++  +G    +D  +L+  + T      + + +  E S  
Sbjct: 247 LTLHQHLDLSSSEKF-HELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWS-- 303

Query: 132 GPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT---SAPVYQQPQQQPVAQSYGGYKE 188
                  ++ +R  S+     R P E      +PT   +AP    P Q P +   G  +E
Sbjct: 304 -------LDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAP----PPQSPGSPGTGQDEE 352

Query: 189 PAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDD-GWMYGTVERT 247
            +   S +++A G    R RA+YDY+  + DE+SF+ G+ ++ + + D+ GW  G ++ +
Sbjct: 353 WSDEESPRKAATG---VRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQ-S 408

Query: 248 GDTGMLPANYVEAI 261
           G  G+ PANYVE +
Sbjct: 409 GRIGLYPANYVECV 422


>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
           sapiens]
          Length = 492

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
           P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 403 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 461

Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
            +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 462 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 261 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 312



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 319 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 375

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 376 NRQGIFPVSYVEVV 389


>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
            sapiens]
          Length = 1004

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178  PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
            P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 915  PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 973

Query: 231  NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
             +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 974  VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1004



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 773 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 824



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 831 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 887

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 888 NRQGIFPVSYVEVV 901


>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
           sapiens]
          Length = 824

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
           P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 735 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 793

Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
            +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 794 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 593 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 644



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 651 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 707

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 708 NRQGIFPVSYVEVV 721


>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
           sapiens]
          Length = 661

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
           P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 572 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 630

Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
            +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 631 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 430 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 481



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 488 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 544

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 545 NRQGIFPVSYVEVV 558


>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
           sapiens]
          Length = 731

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
           P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 642 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 700

Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
            +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 701 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 500 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 551



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 558 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 614

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 615 NRQGIFPVSYVEVV 628


>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 644

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
           P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 555 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 613

Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
            +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 614 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 413 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 464



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 471 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 527

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 528 NRQGIFPVSYVEVV 541


>gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo
           sapiens]
          Length = 671

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 165 PTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR---YRAVYDYSAADEDEV 221
           PT  P  Q         +    + P+ P+ +  S+P         YRA+Y Y   +EDE+
Sbjct: 572 PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDEL 631

Query: 222 SFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
             ++GD +  +QQ DDGW  G   RT   G  P NYV  +
Sbjct: 632 ELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 671



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 11/92 (11%)

Query: 170 VYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTI 229
           VY    + P A + GG   PA     +R A        R  +D+ A    E++ Q GD +
Sbjct: 357 VYPSSTRDPSASNGGG--SPARREEKKRKAA-------RLKFDFQAQSPKELTLQKGDIV 407

Query: 230 VNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
              +++D  W+ G  E  G  G+ PANYVE +
Sbjct: 408 YIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 437



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 17/51 (33%), Positives = 31/51 (60%)

Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259
           A Y +    E E+SF+ G+ I  ++++++ W  G +  TG  G+ PA+YV+
Sbjct: 461 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 511


>gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo
           sapiens]
          Length = 329

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 165 PTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR---YRAVYDYSAADEDEV 221
           PT  P  Q         +    + P+ P+ +  S+P         YRA+Y Y   +EDE+
Sbjct: 230 PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDEL 289

Query: 222 SFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
             ++GD +  +QQ DDGW  G   RT   G  P NYV  +
Sbjct: 290 ELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 329



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 11/92 (11%)

Query: 170 VYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTI 229
           VY    + P A + GG   PA     +R A        R  +D+ A    E++ Q GD +
Sbjct: 15  VYPSSTRDPSASNGGG--SPARREEKKRKAA-------RLKFDFQAQSPKELTLQKGDIV 65

Query: 230 VNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
              +++D  W+ G  E  G  G+ PANYVE +
Sbjct: 66  YIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 95



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 17/51 (33%), Positives = 31/51 (60%)

Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259
           A Y +    E E+SF+ G+ I  ++++++ W  G +  TG  G+ PA+YV+
Sbjct: 119 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 169


>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
            sapiens]
          Length = 1100

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178  PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
            P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 1011 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 1069

Query: 231  NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
             +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 1070 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1100



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 869 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 920



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 927 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 983

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 984 NRQGIFPVSYVEVV 997


>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 666

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230
           P+  SY   +       +P  PV    +  GGG + ++A+Y+Y+  +EDE+  ++ D I 
Sbjct: 577 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 635

Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
            +++ DDGW  GT  RT   G  P NYV+ +
Sbjct: 636 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 666



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           +AVYD+ A    E+SF+ GDT+  +++ID  W  G  E  G  G+ P +YVE +
Sbjct: 435 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 486



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247
           +PA P     + PG  G+   A Y+++A    E+S + GD ++ ++++D  W  G +  T
Sbjct: 493 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 549

Query: 248 GDTGMLPANYVEAI 261
              G+ P +YVE +
Sbjct: 550 NRQGIFPVSYVEVV 563


>gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens]
          Length = 77

 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 24/52 (46%), Positives = 29/52 (55%)

Query: 3  PNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCN 54
          P C +C K VY  E+V  L K WH+ C  CE C  TL    +  +E KPYCN
Sbjct: 2  PKCPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCN 53


>gi|109689723 abl interactor 2 [Homo sapiens]
          Length = 475

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 13/106 (12%)

Query: 165 PTSAPVYQQ-PQQQPVAQSYGGYKEPAAPVSIQRS--------APGGGGKRYRAVYDYSA 215
           P   PV+ + P   P  + Y   +E AA V             AP    ++  A+YDY+ 
Sbjct: 369 PVEEPVFDESPPPPPPPEDYE--EEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTK 426

Query: 216 ADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
             EDE+SFQ+G  I  +++ DDGW  G +   G TG+ P NYVE+I
Sbjct: 427 DKEDELSFQEGAIIYVIKKNDDGWYEGVM--NGVTGLFPGNYVESI 470


>gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo
            sapiens]
          Length = 1151

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 184  GGYKEPAAP---VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240
            GG ++P A    V+  RS        Y+A+Y Y   ++DE+  +DGD +  +++ DDGW 
Sbjct: 1069 GGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWF 1128

Query: 241  YGTVERTGDTGMLPANYVEAI 261
             GT  RT   G  P NYV+ +
Sbjct: 1129 VGTSRRTKQFGTFPGNYVKPL 1149



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 16/53 (30%), Positives = 31/53 (58%)

Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           A ++++   + E+SF+ G+ I  ++Q+D+ W  G +  T   G+ P  YV+ I
Sbjct: 896 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 948



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           RA +D+ A    E+  Q GD +   +QID  W  G  E  G  G+ P  Y+E +
Sbjct: 821 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 872


>gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo
            sapiens]
          Length = 1292

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 184  GGYKEPAAP---VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240
            GG ++P A    V+  RS        Y+A+Y Y   ++DE+  +DGD +  +++ DDGW 
Sbjct: 1210 GGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWF 1269

Query: 241  YGTVERTGDTGMLPANYVEAI 261
             GT  RT   G  P NYV+ +
Sbjct: 1270 VGTSRRTKQFGTFPGNYVKPL 1290



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 16/53 (30%), Positives = 31/53 (58%)

Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           A ++++   + E+SF+ G+ I  ++Q+D+ W  G +  T   G+ P  YV+ I
Sbjct: 874 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 926



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 2/54 (3%)

Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           RA +D+ A    E+  Q GD +   +QID  W  G  E  G  G+ P  Y+E +
Sbjct: 799 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 850


>gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens]
          Length = 529

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 41/136 (30%), Positives = 66/136 (48%), Gaps = 19/136 (13%)

Query: 128 KSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYK 187
           +SR G SG  G EP+ R +      RR L +      P+++ +Y    Q   + S+G   
Sbjct: 267 RSRHG-SGSYGTEPDARPASQLEPDRRSLPRT-----PSASSLYSGSAQSSRSNSFG--- 317

Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYS-AADEDEVSFQDGDTI-VNVQQIDDGWMYGTVE 245
                   +R   GGG +R RA+  +S  A+   + F  GD + V V +  +GW+YG +E
Sbjct: 318 --------ERPGGGGGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLE 369

Query: 246 RTGDTGMLPANYVEAI 261
            +  +G  P  YV+A+
Sbjct: 370 GSSASGWFPEAYVKAL 385


>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
          Length = 731

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 2/56 (3%)

Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259
           G++ +A+YD+   +EDE+SF+ GD I  ++ +DD WM G  E  G +G+ P NY++
Sbjct: 673 GRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSG--ELMGKSGIFPKNYIQ 726



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)

Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           G R  A ++Y    +DE+SF +G+ I+  + +++ W  G V   G TG+ P N+VE +
Sbjct: 514 GSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVEPV 569



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 210 VYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           ++D+ A   D+++   G+ +  +++ID  W  G        G+ PANYV+ I
Sbjct: 444 LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCR--NQIGIFPANYVKVI 493



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 2/50 (4%)

Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYV 258
           A++ ++A   D++SF+ GD I  ++++D  W  G ++     G+ PA +V
Sbjct: 609 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ--DREGIFPAVFV 656


>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
          Length = 767

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 2/56 (3%)

Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259
           G++ +A+YD+   +EDE+SF+ GD I  ++ +DD WM G  E  G +G+ P NY++
Sbjct: 709 GRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSG--ELMGKSGIFPKNYIQ 762



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)

Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           G R  A ++Y    +DE+SF +G+ I+  + +++ W  G V   G TG+ P N+VE +
Sbjct: 550 GSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVEPV 605



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 210 VYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           ++D+ A   D+++   G+ +  +++ID  W  G        G+ PANYV+ I
Sbjct: 480 LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCR--NQIGIFPANYVKVI 529



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 2/50 (4%)

Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYV 258
           A++ ++A   D++SF+ GD I  ++++D  W  G ++     G+ PA +V
Sbjct: 645 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ--DREGIFPAVFV 692


>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
          Length = 790

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 2/56 (3%)

Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259
           G++ +A+YD+   +EDE+SF+ GD I  ++ +DD WM G  E  G +G+ P NY++
Sbjct: 732 GRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSG--ELMGKSGIFPKNYIQ 785



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)

Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           G R  A ++Y    +DE+SF +G+ I+  + +++ W  G V   G TG+ P N+VE +
Sbjct: 573 GSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVEPV 628



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 210 VYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261
           ++D+ A   D+++   G+ +  +++ID  W  G        G+ PANYV+ I
Sbjct: 503 LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCR--NQIGIFPANYVKVI 552



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 2/50 (4%)

Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYV 258
           A++ ++A   D++SF+ GD I  ++++D  W  G ++     G+ PA +V
Sbjct: 668 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ--DREGIFPAVFV 715


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,397,996
Number of Sequences: 37866
Number of extensions: 570778
Number of successful extensions: 2872
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 278
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 1886
Number of HSP's gapped (non-prelim): 960
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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