BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5453710 LIM and SH3 protein 1 [Homo sapiens] (261 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 551 e-157 gi|47087157 nebulette non-muscle isoform [Homo sapiens] 340 7e-94 gi|115527120 nebulin [Homo sapiens] 123 1e-28 gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 120 9e-28 gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 105 3e-23 gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 105 3e-23 gi|20357552 cortactin isoform a [Homo sapiens] 66 3e-11 gi|20357556 cortactin isoform b [Homo sapiens] 66 3e-11 gi|21361670 drebrin-like isoform a [Homo sapiens] 64 1e-10 gi|62198235 drebrin-like isoform b [Homo sapiens] 63 3e-10 gi|171906575 drebrin-like isoform c [Homo sapiens] 62 4e-10 gi|19224660 protein kinase C and casein kinase substrate in neur... 60 3e-09 gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 59 4e-09 gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ... 59 4e-09 gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 59 4e-09 gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 59 4e-09 gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 59 4e-09 gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 59 4e-09 gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ... 59 4e-09 gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s... 59 4e-09 gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s... 59 4e-09 gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ... 59 4e-09 gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] 59 4e-09 gi|109689723 abl interactor 2 [Homo sapiens] 58 1e-08 gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s... 57 2e-08 gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo s... 57 2e-08 gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens] 57 2e-08 gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 56 3e-08 gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 56 3e-08 gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 56 3e-08 >gi|5453710 LIM and SH3 protein 1 [Homo sapiens] Length = 261 Score = 551 bits (1420), Expect = e-157 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 60 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ Sbjct: 1 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 60 Query: 61 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI Sbjct: 61 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120 Query: 121 KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA 180 KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA Sbjct: 121 KYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVA 180 Query: 181 QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240 QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM Sbjct: 181 QSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240 Query: 241 YGTVERTGDTGMLPANYVEAI 261 YGTVERTGDTGMLPANYVEAI Sbjct: 241 YGTVERTGDTGMLPANYVEAI 261 >gi|47087157 nebulette non-muscle isoform [Homo sapiens] Length = 270 Score = 340 bits (872), Expect = 7e-94 Identities = 170/277 (61%), Positives = 200/277 (72%), Gaps = 24/277 (8%) Query: 1 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQ 60 MNP CARCGK+VYPTEKVNCLDK+WHK CFHCE CKM LNM NYKGYEKKPYCNAHYPKQ Sbjct: 1 MNPQCARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQ 60 Query: 61 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120 SFT VADTPENLRLKQQSELQSQV+YK +FE++KG+GFS+V DTPELQR+K+TQ+QISN+ Sbjct: 61 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120 Query: 121 KYHEEFEKSRMGPSGGEGMEP---------ERRDSQDGSSYRRPLEQQQPHHIPTS---- 167 KYHE+FEK++ G G P R+++Q S + PH + Sbjct: 121 KYHEDFEKTK-----GRGFTPVVDDPVTERVRKNTQVVSD--AAYKGVHPHIVEMDRRPG 173 Query: 168 ---APVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQ 224 APV QQ +Q Y GY + S++ + YRA+YDYSA DEDEVSF+ Sbjct: 174 IIVAPVLPGAYQQSHSQGY-GYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFR 232 Query: 225 DGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 DGD IVNVQ IDDGWMYGTV+RTG TGMLPANY+E + Sbjct: 233 DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269 >gi|115527120 nebulin [Homo sapiens] Length = 6669 Score = 123 bits (309), Expect = 1e-28 Identities = 94/258 (36%), Positives = 117/258 (45%), Gaps = 66/258 (25%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 V DTPE R+++ S V+Y E+FEK+KG VV D P +R+KK S+I Y Sbjct: 6417 VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTD-PITERVKKNMQDFSDINYRG 6475 Query: 125 ------EFEKSR---------------MGPSGGEGMEPERRDSQDGSSY-------RRPL 156 E E+ R P +P + Q S + RR Sbjct: 6476 IQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSR 6535 Query: 157 EQQQP--------------------HHIPTSAPVYQQPQQQPVAQSYGGYKEPAAP---- 192 EQ + HH+ T Y V+ +Y K P Sbjct: 6536 EQSRSASALSISGGEEKSEHSEAPDHHLST----YSDGGVFAVSTAYKHAKTTELPQQRS 6591 Query: 193 ---------VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGT 243 VS S P GK +RA+YDY AAD DEVSF+DGD I+NVQ ID+GWMYGT Sbjct: 6592 SSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGT 6651 Query: 244 VERTGDTGMLPANYVEAI 261 V+RTG TGMLPANYVEAI Sbjct: 6652 VQRTGRTGMLPANYVEAI 6669 Score = 67.0 bits (162), Expect = 2e-11 Identities = 31/90 (34%), Positives = 55/90 (61%), Gaps = 8/90 (8%) Query: 41 MKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100 +K K YEK K FT + DTPE+LR + ++ S + YK E+ K K +G++ Sbjct: 5439 IKYRKNYEKS--------KDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTT 5490 Query: 101 VADTPELQRIKKTQDQISNIKYHEEFEKSR 130 + DTP L ++K +D++S++KY E +++++ Sbjct: 5491 IHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520 Score = 62.0 bits (149), Expect = 5e-10 Identities = 39/112 (34%), Positives = 56/112 (50%), Gaps = 4/112 (3%) Query: 22 DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQS 78 D W K C+ +T TL KN Y K Y K F VAD+P N K + Sbjct: 5339 DLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYAT 5398 Query: 79 ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 +L ++ +Y+ ++E+ K K + +V D P K DQIS IKY + +EKS+ Sbjct: 5399 QLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449 Score = 58.9 bits (141), Expect = 4e-09 Identities = 27/55 (49%), Positives = 38/55 (69%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 TP ++ +L S +YKE+FEK KG+ ++ DTPEL+RIKK QDQ+S +KY Sbjct: 83 TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKY 137 Score = 58.5 bits (140), Expect = 6e-09 Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Query: 54 NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113 +A K +FT V DTPE + +Q L SQ +YKE+ EK+ + V DTPE+QR+++ Sbjct: 6052 SAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSY-YETVLDTPEIQRVREN 6110 Query: 114 QDQISNIKYHEEFEKSR 130 Q S ++Y + + S+ Sbjct: 6111 QKNFSLLQYQCDLKNSK 6127 Score = 58.5 bits (140), Expect = 6e-09 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 6/84 (7%) Query: 42 KNYKGYEKKPY-CNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100 +N K + Y C+ K T+V DTPE LR+K+ + S V YKE+ + Sbjct: 6109 ENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPG-----TA 6163 Query: 101 VADTPELQRIKKTQDQISNIKYHE 124 + TPE+ R+K+TQD IS++KY E Sbjct: 6164 IGKTPEMMRVKQTQDHISSVKYKE 6187 Score = 58.2 bits (139), Expect = 7e-09 Identities = 28/63 (44%), Positives = 39/63 (61%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 TPE R K+ E S V Y + F K + V DTPE++R+++TQ IS +KYHE+FE Sbjct: 6384 TPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFE 6443 Query: 128 KSR 130 K + Sbjct: 6444 KHK 6446 Score = 57.0 bits (136), Expect = 2e-08 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 10/101 (9%) Query: 31 HCETCKMTLNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89 H + +N K Y+ YE++ K + +V D P +L K + SQ++Y++ Sbjct: 5393 HFKYATQLMNEKKYRADYEQR--------KDKYHLVVDEPRHLLAKTAGDQISQIKYRKN 5444 Query: 90 FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 +EK+K K F+ + DTPE R K QIS+I Y E+ K++ Sbjct: 5445 YEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAK 5484 Score = 53.9 bits (128), Expect = 1e-07 Identities = 32/111 (28%), Positives = 61/111 (54%), Gaps = 6/111 (5%) Query: 23 KFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQS 82 K+ CF +M + + + Y++ + Q + M +TPE K+ S Sbjct: 288 KWSETPCFEVANARMNADNISTRKYQED---FENMKDQIYFMQTETPEYKMNKKAGVAAS 344 Query: 83 QVRYKEEFEKNKGKG-FSVV--ADTPELQRIKKTQDQISNIKYHEEFEKSR 130 +V+YKE++EKNKGK ++V+ ++ P+L+++K D +S+ Y E +EK++ Sbjct: 345 KVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTK 395 Score = 53.5 bits (127), Expect = 2e-07 Identities = 36/97 (37%), Positives = 49/97 (50%), Gaps = 10/97 (10%) Query: 31 HCETCKMTLNMKNYK-GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89 H + K ++ K YK YEK K +T V DTP +R K+ S +RYKE Sbjct: 5218 HAKDVKDMVSEKKYKIQYEKM--------KDKYTPVPDTPILIRAKRAYWNASDLRYKET 5269 Query: 90 FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126 F+K KGK + V D ++ +K D IS IKY E + Sbjct: 5270 FQKTKGK-YHTVKDALDIVYHRKVTDDISKIKYKENY 5305 Score = 51.6 bits (122), Expect = 7e-07 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 9/156 (5%) Query: 41 MKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFS 99 +KN + KK Y K F D+PE R+ Q + S V YK+ + + + F+ Sbjct: 196 VKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQ-FT 254 Query: 100 VVADTPELQRIKKTQDQISNIKYHEEFEKSRMG-----PSGGEGMEPERRDSQDGSSYRR 154 +AD P+++ KK +Q+S KY E++E G P D+ Y+ Sbjct: 255 PLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQE 314 Query: 155 PLE--QQQPHHIPTSAPVYQQPQQQPVAQSYGGYKE 188 E + Q + + T P Y+ ++ VA S YKE Sbjct: 315 DFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKE 350 Score = 51.6 bits (122), Expect = 7e-07 Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 19/152 (12%) Query: 16 EKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLK 75 EK N H + K + K YK +A + V DTPE R++ Sbjct: 6056 EKANFTSVVDTPEIIHAQQVKNLSSQKKYKE-------DAEKSMSYYETVLDTPEIQRVR 6108 Query: 76 QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSG 135 + + S ++Y+ + + +KGK +VV DTPE+ R+K+ Q S++ Y E+ + P Sbjct: 6109 ENQKNFSLLQYQCDLKNSKGK-ITVVQDTPEILRVKENQKNFSSVLYKED-----VSPGT 6162 Query: 136 GEGMEPER---RDSQDGSS---YRRPLEQQQP 161 G PE + +QD S Y+ + Q P Sbjct: 6163 AIGKTPEMMRVKQTQDHISSVKYKEAIGQGTP 6194 Score = 50.8 bits (120), Expect = 1e-06 Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 9/99 (9%) Query: 34 TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93 T ++ + + K YEK K + + D E L LK+ +ELQS V+YKE++EK Sbjct: 5858 TSQLASSYQYKKKYEKS--------KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKE 5909 Query: 94 KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMG 132 +GK + +TP K++Q S +Y +++E+S G Sbjct: 5910 RGKPM-LDFETPTYITAKESQQMQSGKEYRKDYEESIKG 5947 Score = 50.4 bits (119), Expect = 2e-06 Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 8/101 (7%) Query: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 T +A TPE R+K E S V YKE N GK + TPE+QR+K+ Q+ IS++ Y Sbjct: 6286 TPLAVTPEMERVKHNQENISSVLYKE----NVGKATATPV-TPEMQRVKRNQENISSVLY 6340 Query: 123 HEEFEKSRMGPSGGEGMEPERRDSQDGSS--YRRPLEQQQP 161 E K+ P E ME +R+ ++ SS Y+ + + P Sbjct: 6341 KENLGKATPTPFTPE-MERVKRNQENFSSVLYKENMRKATP 6380 Score = 47.4 bits (111), Expect = 1e-05 Identities = 23/66 (34%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Query: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYH 123 M +TP+ +R + +++ SQ++YK+ E K F+ V DTPE+ ++ ++ S KY Sbjct: 6027 MANETPDFMRARNATDIASQIKYKQSAEMEKA-NFTSVVDTPEIIHAQQVKNLSSQKKYK 6085 Query: 124 EEFEKS 129 E+ EKS Sbjct: 6086 EDAEKS 6091 Score = 47.4 bits (111), Expect = 1e-05 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 5/62 (8%) Query: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 T + TPE +R+KQ + S V+YKE G+G + + D PE++R+K+TQ IS++ Y Sbjct: 6162 TAIGKTPEMMRVKQTQDHISSVKYKEAI----GQG-TPIPDLPEVKRVKETQKHISSVMY 6216 Query: 123 HE 124 E Sbjct: 6217 KE 6218 Score = 45.8 bits (107), Expect = 4e-05 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 6/89 (6%) Query: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 T + D PE R+K+ + S V YKE N G G TPE++R+K+ Q+ S++ Y Sbjct: 6193 TPIPDLPEVKRVKETQKHISSVMYKE----NLGTGIPTTV-TPEIERVKRNQENFSSVLY 6247 Query: 123 HEEFEKSRMGPSGGEGMEPERRDSQDGSS 151 E K P E ME +R+ ++ SS Sbjct: 6248 KENLGKGIPTPITPE-MERVKRNQENFSS 6275 Score = 45.4 bits (106), Expect = 5e-05 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Query: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 +T ++ L N K Y A K S ++ DTP+ L K S SQ Y + ++ Sbjct: 3676 DTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWD 3735 Query: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 ++K K + + AD ++ K ++D S+ KY E +EK + G + +E + Sbjct: 3736 ESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDD 3786 Score = 45.1 bits (105), Expect = 6e-05 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 6/84 (7%) Query: 47 YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106 Y K N HY T VAD P+ + Q ++ S+V Y+ + K G S++ P+ Sbjct: 5726 YRKDAKENLHY-----TTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG-RPD 5779 Query: 107 LQRIKKTQDQISNIKYHEEFEKSR 130 ++ KK S +KY E F+K + Sbjct: 5780 IEMAKKAAKLSSQVKYRENFDKEK 5803 Score = 44.7 bits (104), Expect = 8e-05 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Query: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVA-DTPELQRIKKTQDQI 117 + T + DTP+ LR K +++ ++ YK + E KG+G + +A +TP+ R + D Sbjct: 5985 KGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIA 6044 Query: 118 SNIKYHEEFEKSR 130 S IKY + E + Sbjct: 6045 SQIKYKQSAEMEK 6057 Score = 44.3 bits (103), Expect = 1e-04 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 ++T N + + K +YP +F V D PE + K S QS V+YKE F K KG Sbjct: 4376 RVTKNQEMMSQIKYKKNALENYP--NFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKG 4433 Query: 96 KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 K ++ DTP + K S I Y +E ++ Sbjct: 4434 K-YTFSPDTPHISHSKDMGKLYSTILYKGAWEGTK 4467 Score = 44.3 bits (103), Expect = 1e-04 Identities = 23/98 (23%), Positives = 54/98 (55%), Gaps = 6/98 (6%) Query: 33 ETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92 +T ++ YK + KK H + S+T + +T + + +K+ ++ S YK++F K Sbjct: 5641 KTVSNLVSENKYKDHVKK-----HLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVK 5695 Query: 93 NKGK-GFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 KGK +S++ + PE++ + + S++ Y ++ +++ Sbjct: 5696 EKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKEN 5733 Score = 43.9 bits (102), Expect = 1e-04 Identities = 24/75 (32%), Positives = 37/75 (49%) Query: 54 NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113 N H K +T V +T + R + L S YKE +++ K + + + T L K Sbjct: 4672 NYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQ 4731 Query: 114 QDQISNIKYHEEFEK 128 + S+IKY EE+EK Sbjct: 4732 KHLASHIKYREEYEK 4746 Score = 43.9 bits (102), Expect = 1e-04 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 TPE R+K+ E S V YKE K + TPE++R K+ Q+ IS++ Y + F Sbjct: 6353 TPEMERVKRNQENFSSVLYKENMRKA-----TPTPVTPEMERAKRNQENISSVLYSDSFR 6407 Query: 128 KSRMGPSGGEGMEPERR 144 K G + PE R Sbjct: 6408 KQIQGKAAYVLDTPEMR 6424 Score = 43.1 bits (100), Expect = 2e-04 Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 1/117 (0%) Query: 27 KACFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVR 85 K + +T + LN N +K+ Y + K + ++ DTP+ L + S Sbjct: 1724 KFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKL 1783 Query: 86 YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 YK +E+ K KG+ + D ++ + ++D S+ KY + +E+++ G +E + Sbjct: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDD 1840 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 9/102 (8%) Query: 65 VADTPENLRLKQ---QSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 V D E+L + S+L S +YK+++EK+KG + + D E +K+ + S +K Sbjct: 5843 VTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGH-YHTIPDNLEQLHLKEATELQSIVK 5901 Query: 122 YHEEFEKSRMGP-----SGGEGMEPERRDSQDGSSYRRPLEQ 158 Y E++EK R P + E + Q G YR+ E+ Sbjct: 5902 YKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEE 5943 Score = 42.7 bits (99), Expect = 3e-04 Identities = 23/70 (32%), Positives = 37/70 (52%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K ++ DTP+ L+ KQ L SQ YK +E+ KG+ + D +Q K ++D S Sbjct: 2245 KTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIAS 2304 Query: 119 NIKYHEEFEK 128 + KY + + K Sbjct: 2305 DYKYKQGYRK 2314 Score = 42.7 bits (99), Expect = 3e-04 Identities = 28/110 (25%), Positives = 55/110 (50%), Gaps = 6/110 (5%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 +T + DTPE + K +E S +Y+E ++K+K ++ DTPE+ + +SN Sbjct: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDK-TSIHIMPDTPEINLARANALNVSNKL 3972 Query: 122 YHEEFEKSRMGPS---GGEGMEPERRDSQDGSSYRRPL--EQQQPHHIPT 166 Y E +++ + G ++ + + S Y+ L E+Q+ H++ T Sbjct: 3973 YREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGT 4022 Score = 42.7 bits (99), Expect = 3e-04 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 36/107 (33%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQV---------------------------------- 84 K FT V DTP+ LR K+ +LQSQ Sbjct: 5169 KSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSE 5228 Query: 85 -RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 +YK ++EK K K ++ V DTP L R K+ S+++Y E F+K++ Sbjct: 5229 KKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYKETFQKTK 5274 Score = 42.4 bits (98), Expect = 4e-04 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 4/98 (4%) Query: 31 HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90 H + K T M +Y Y K+ Y H +T+ + +++ + + S+ Y+E + Sbjct: 4969 HFKHIKDTRYMSSYFKY-KEAY--EHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025 Query: 91 EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128 K K K DTPE++++KKTQ+ +S + Y +F K Sbjct: 5026 HKLKDK-IHTTPDTPEIRQVKKTQEAVSELIYKSDFFK 5062 Score = 42.4 bits (98), Expect = 4e-04 Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 5/61 (8%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 TPE R+K+ E S V YKE N GKG TPE++R+K+ Q+ S++ Y E Sbjct: 6229 TPEIERVKRNQENFSSVLYKE----NLGKGIPTPI-TPEMERVKRNQENFSSVLYKENMG 6283 Query: 128 K 128 K Sbjct: 6284 K 6284 Score = 41.2 bits (95), Expect = 0.001 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 43 NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102 NYK + H P DTP ++ K + S YK+++EK+K K F + Sbjct: 525 NYKAKHESEKFKCHIPP-------DTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKV 577 Query: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130 D L K S++ Y +++EK++ Sbjct: 578 DAIPLLAAKANTKNTSDVMYKKDYEKNK 605 Score = 41.2 bits (95), Expect = 0.001 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 7/88 (7%) Query: 43 NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102 NYK + H P AD P+ ++ + + S YK+++EK+K K F + Sbjct: 772 NYKAKHEGEKFKCHIP-------ADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKV 824 Query: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130 D L K S++ Y +++EKS+ Sbjct: 825 DAIPLLAAKANTKNTSDVMYKKDYEKSK 852 Score = 41.2 bits (95), Expect = 0.001 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Query: 49 KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108 KK Y A F + D P+ + +++QS YK+++EK K K ++ D + Sbjct: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK-YNTPHDMFNVV 1147 Query: 109 RIKKTQDQISNIKY 122 KK QD +SN+ Y Sbjct: 1148 AAKKAQDVVSNVNY 1161 Score = 40.8 bits (94), Expect = 0.001 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Query: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117 + F + D L K ++ S V YK+++EK+KGK G + D P++ KT Sbjct: 818 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQ 877 Query: 118 SNIKYHEEFEKSR 130 S+ +Y +++EKS+ Sbjct: 878 SDREYRKDYEKSK 890 Score = 40.8 bits (94), Expect = 0.001 Identities = 23/72 (31%), Positives = 38/72 (52%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K +TM D P+ L+ K + S V YK ++ KG +V+ D + K +++ S Sbjct: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328 Query: 119 NIKYHEEFEKSR 130 + KY E +EKS+ Sbjct: 1329 DYKYKEAYEKSK 1340 Score = 40.8 bits (94), Expect = 0.001 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 7/109 (6%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 FT + DTPE + K + S+ Y E ++ +K V+ DTP++ K IS Sbjct: 3671 FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-TSIHVMPDTPDILLAKSNSANISQKL 3729 Query: 122 YHEEFEKSRM------GPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHI 164 Y + +++S+M + RD Y+ E+Q+ HHI Sbjct: 3730 YTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHI 3778 Score = 40.4 bits (93), Expect = 0.002 Identities = 23/70 (32%), Positives = 35/70 (50%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K + ++ DTPE L KQ S+ YK E+ K KG+ + D ++ K ++D S Sbjct: 2731 KTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIAS 2790 Query: 119 NIKYHEEFEK 128 KY E + K Sbjct: 2791 EFKYKEGYRK 2800 Score = 40.4 bits (93), Expect = 0.002 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 1/111 (0%) Query: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 ++ + L N K+ Y A K ++ DTPE + +Q S+ YK E Sbjct: 2947 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANE 3006 Query: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 + K KG+ + +D + K ++D IS+ KY + + K G +E + Sbjct: 3007 EAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057 Score = 40.0 bits (92), Expect = 0.002 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 V DTPE L K +L+ ++YK K + + +V DTP + K+ Q+S+ YH Sbjct: 4858 VWDTPEILHAKHAYDLRDDIKYKAHMLKTR-NDYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916 Query: 125 EFEKSRMG 132 ++ S G Sbjct: 4917 DYVHSVRG 4924 Score = 40.0 bits (92), Expect = 0.002 Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 3/95 (3%) Query: 34 TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93 T K + M++ K Y K ++ T + TP L +K +++ S+ Y+++ E++ Sbjct: 5924 TAKESQQMQSGKEYRKD--YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEES 5981 Query: 94 -KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 +GKG + + DTP++ R K ++ +Y + E Sbjct: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLE 6016 Score = 39.7 bits (91), Expect = 0.003 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%) Query: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA--DTPELQRIKKTQDQI 117 + F + D L K ++ S V YK+++EKNKGK V++ D P++ K Sbjct: 571 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQ 630 Query: 118 SNIKYHEEFEKSR 130 S+ Y E +EK++ Sbjct: 631 SDRLYKENYEKTK 643 Score = 39.3 bits (90), Expect = 0.003 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 17/114 (14%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 FT + DTPE + K + ++ Y E ++ +K K V+ DTPE+ K ++ I Sbjct: 3428 FTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK-----LNRIN 3481 Query: 122 YHEEFEKSRMGPSGGEGME-----------PERRDSQDGSSYRRPLEQQQPHHI 164 Y ++ K + S EG + RD Y+ +Q HHI Sbjct: 3482 YSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHI 3535 Score = 39.3 bits (90), Expect = 0.003 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Query: 67 DTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126 D+ +++R+ + E+ SQ++YK+ +N F V D PE+ K S++KY E F Sbjct: 4370 DSVDHVRVTKNQEMMSQIKYKKNALENY-PNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428 Query: 127 EKSR 130 K++ Sbjct: 4429 NKAK 4432 Score = 38.5 bits (88), Expect = 0.006 Identities = 18/72 (25%), Positives = 38/72 (52%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K +T+ + P+ ++ K + S YK +++K KG+ + D + K +++ S Sbjct: 1513 KHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIAS 1572 Query: 119 NIKYHEEFEKSR 130 + KY E +EK++ Sbjct: 1573 DCKYKEAYEKAK 1584 Score = 38.5 bits (88), Expect = 0.006 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 + D PE+ + ++ S V+YKE+ KG G DTP+ +K + S KY E Sbjct: 5315 IPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG-CYAYDTPDFTLAEKNKTLYSKYKYKE 5373 Query: 125 EFEKSR 130 FE+++ Sbjct: 5374 VFERTK 5379 Score = 38.5 bits (88), Expect = 0.006 Identities = 19/67 (28%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKG-FSVVADTPELQRIKKTQDQISNIKYH 123 V DTP+ L K S L S+ +YK+ +K+ +G ++ + +T + +K+ +S+ Y Sbjct: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690 Query: 124 EEFEKSR 130 ++F K + Sbjct: 5691 KKFVKEK 5697 Score = 38.1 bits (87), Expect = 0.008 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Query: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 ++ + L N K+ Y A K ++ DTPE + +Q S+ Y++ E Sbjct: 3190 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAME 3249 Query: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128 + K +G+ + +D + K ++D S+ KY E + K Sbjct: 3250 EAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRK 3286 Score = 38.1 bits (87), Expect = 0.008 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 H K DTPE ++K+ E S++ YK +F K +G S + TP++ + D Sbjct: 5026 HKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMIS-LPYTPQVIHCRYVGD 5084 Query: 116 QISNIKYHEEFE 127 S+IKY E+ + Sbjct: 5085 ITSDIKYKEDLQ 5096 Score = 37.7 bits (86), Expect = 0.010 Identities = 30/128 (23%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 31 HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90 H C + YK K HY + D P+ + + ++Q++ YKE++ Sbjct: 4237 HAHHCNDVQSELKYKAEHVKQ--KGHYV--GVPTMRDDPKLVWFEHAGQIQNERLYKEDY 4292 Query: 91 EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDG 149 K K K ++ AD + K+ Q +S+I Y + P + ++ + D Q Sbjct: 4293 HKTKAK-INIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351 Query: 150 SSYRRPLE 157 + YR LE Sbjct: 4352 NVYRADLE 4359 Score = 37.4 bits (85), Expect = 0.013 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQ 116 K+ + + D K + S V+YK+++EK KGK GF + D P+L Sbjct: 1061 KKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKI 1120 Query: 117 ISNIKYHEEFEKSR 130 S+ +Y +++EK++ Sbjct: 1121 QSDREYKKDYEKTK 1134 Score = 37.4 bits (85), Expect = 0.013 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 1/111 (0%) Query: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 ++ M L N K + Y A K ++ D P+ + K + S YK E Sbjct: 1974 DSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLE 2033 Query: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 ++K KG+ + D ++ K ++D S+ KY +EK + G +E + Sbjct: 2034 ESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDD 2084 Score = 37.4 bits (85), Expect = 0.013 Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Query: 22 DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFTMVADTPENLRLKQQS 78 D W K C+ +T ++ K+Y + Y A Q++ +V DTP + Q Sbjct: 4602 DLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSG 4661 Query: 79 ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128 S+V+YKE + + K K ++ V +T + R + ++ S+ Y E +++ Sbjct: 4662 INASEVKYKENYHQIKDK-YTTVLETVDYDRTRNLKNLYSSNLYKEAWDR 4710 Score = 37.0 bits (84), Expect = 0.017 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 1/85 (1%) Query: 49 KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108 KK Y A F + D P+ + Q +++QS YK+ +EK+K F D + Sbjct: 1821 KKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSK-TSFHTPVDMLSVV 1879 Query: 109 RIKKTQDQISNIKYHEEFEKSRMGP 133 KK+Q+ +N Y M P Sbjct: 1880 AAKKSQEVATNANYRNVIHTYNMLP 1904 Score = 37.0 bits (84), Expect = 0.017 Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 69 PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQI-SNIKYHEEFE 127 P+ K+ ++L SQV+Y+E F+K KGK +L ++ K + + S +KY + + Sbjct: 5778 PDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLK 5837 Query: 128 K 128 K Sbjct: 5838 K 5838 Score = 36.6 bits (83), Expect = 0.023 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 7/117 (5%) Query: 42 KNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVV 101 K + YEK+ H QS + D P+ + ++QS+ YK+EF+K K K FS Sbjct: 3765 KYKEAYEKQK--GHHIGAQS---IEDDPKIMCAIHAGKIQSEREYKKEFQKWKTK-FSSP 3818 Query: 102 ADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 D + KK Q +++I Y + P + ++ ++ D Q + Y+ LE Sbjct: 3819 VDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLE 3875 Score = 36.2 bits (82), Expect = 0.030 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Query: 67 DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 +TP + K+ ++QS Y++++E++ KG+ + + TP L +K S +Y ++ Sbjct: 5918 ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKD 5977 Query: 126 FEKSRMG 132 E+S G Sbjct: 5978 LEESIRG 5984 Score = 35.8 bits (81), Expect = 0.039 Identities = 41/171 (23%), Positives = 65/171 (38%), Gaps = 13/171 (7%) Query: 27 KACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVA--DTPENLRLKQQSELQSQV 84 K+ +CET K L+ K Y +++ V + P + + + S Sbjct: 397 KSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDK 456 Query: 85 RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144 YK E+E+++GKGF T E + IKK DQ + Y +K++ P Sbjct: 457 NYKAEYEEDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTKFTQVTD---SPVLL 512 Query: 145 DSQDGSSYRRPLEQQQPH-------HIPTSAPVYQQPQQQPVAQSYGGYKE 188 +Q S L + H HIP P + Q + S YK+ Sbjct: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQ 563 Score = 35.8 bits (81), Expect = 0.039 Identities = 35/152 (23%), Positives = 60/152 (39%), Gaps = 24/152 (15%) Query: 35 CKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNK 94 CK + + Y + P K FT V D+ E + K + ++ Y E ++K+K Sbjct: 3164 CKRAAEILSDNIYRQPP------DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 3217 Query: 95 GKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGME-----------PER 143 + ++ DTPE+ ++ + I Y E + M + EG + Sbjct: 3218 TQ-VHIMPDTPEIMLARQ-----NKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKAS 3271 Query: 144 RDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQ 175 RD Y+ +Q HHI A V+ P+ Sbjct: 3272 RDIASDYKYKEAYRKQLGHHIGARA-VHDDPK 3302 Score = 35.4 bits (80), Expect = 0.050 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 8/121 (6%) Query: 10 KIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTP 69 K VY K NC + H + K + Y+K+ N K + D P Sbjct: 5513 KEVYQRNKSNCTIE---PDAVHIKAAKDAYKVNTNLDYKKQYEAN----KAHWKWTPDRP 5565 Query: 70 ENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 + L+ + S QS YK + E KG SV D + ++ T + S++KY E+ K Sbjct: 5566 DFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIE-SDLKYKEKHVKE 5624 Query: 130 R 130 R Sbjct: 5625 R 5625 Score = 35.0 bits (79), Expect = 0.066 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 17/97 (17%) Query: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 K++L KGY+ +P D K ++ S +YK +EK KG Sbjct: 2029 KLSLEESKKKGYDLRP---------------DAIPIKAAKASRDIASDYKYKYNYEKGKG 2073 Query: 96 K--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 K GF + D P+L + S+ +Y + +E ++ Sbjct: 2074 KMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTK 2110 Score = 34.7 bits (78), Expect = 0.086 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 66 ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 ++ P+ +LK + S YKE +EK K K + +TP+ + Q+ S+ KY + Sbjct: 367 SENPQLRQLKAAGDALSDKLYKENYEKTKAKSIN-YCETPKFKLDTVLQNFSSDKKYKDS 425 Query: 126 FEKSRMGPSGGEGMEP 141 + K +G G +P Sbjct: 426 YLKDILGHYVGSFEDP 441 Score = 34.7 bits (78), Expect = 0.086 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 75 KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 K + S +YKE +EK+KGK GF + D P+L S+ +Y + +E ++ Sbjct: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK 1378 Score = 34.7 bits (78), Expect = 0.086 Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 F + D P+ + +++QS+ YK++FEK K K FS D + KK Q+ +S++ Sbjct: 2322 FRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQELVSDVD 2380 Query: 122 YHEEFEKSRMGPSGGEGMEPER-RDSQDGSSYRRPLE 157 Y + P + ++ ++ + Q + Y+ LE Sbjct: 2381 YKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLE 2417 Score = 34.7 bits (78), Expect = 0.086 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 + D P+ + +++QS YK+EFEK K K FS D + KK Q +S+I Y Sbjct: 3540 IKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK-FSSPVDMLGVVLAKKCQILVSDIDYKH 3598 Query: 125 EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 + P + ++ + D Q + Y+ LE Sbjct: 3599 PLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLE 3632 Score = 34.7 bits (78), Expect = 0.086 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 TP+ + + ++ S ++YKE+ + KG G + DTP++ R + + SN Y ++ Sbjct: 5073 TPQVIHCRYVGDITSDIKYKEDLQVLKGFG-CFLYDTPDMVRSRHLRKLWSNYLYTDKAR 5131 Query: 128 KSR 130 K R Sbjct: 5132 KMR 5134 Score = 34.3 bits (77), Expect = 0.11 Identities = 21/84 (25%), Positives = 37/84 (44%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K ++ DTP+ + K S Y+ +E+ K KG+ + D ++ K +++ S Sbjct: 2488 KTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIAS 2547 Query: 119 NIKYHEEFEKSRMGPSGGEGMEPE 142 KY E F K G +E + Sbjct: 2548 EYKYKEGFRKQLGHHIGARNIEDD 2571 Score = 33.9 bits (76), Expect = 0.15 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Query: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISN 119 Q + DTPE R+K+ + S+V+Y+ + + K V +++ KK Q+S Sbjct: 111 QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAK-TICHVDEKAKDIEHAKKVSQQVSK 169 Query: 120 IKYHEEFEKSR 130 + Y + +E ++ Sbjct: 170 VLYKQNWEDTK 180 Score = 33.9 bits (76), Expect = 0.15 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 49 KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108 K+ Y A + F + D P+ + +++QS YK+ +E +K K + D + Sbjct: 1577 KEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK-YHTPLDMVSVT 1635 Query: 109 RIKKTQDQISNIKYHEEFEKSRMGP 133 KK+Q+ +N Y + + + P Sbjct: 1636 AAKKSQEVATNANYRQSYHHYTLLP 1660 Score = 33.5 bits (75), Expect = 0.19 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 10/88 (11%) Query: 39 LNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGF 98 LN K Y+ H FT + D+P ++ KQ ++ S + YK + E K K + Sbjct: 1223 LNEKKYR---------QHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHK-Y 1272 Query: 99 SVVADTPELQRIKKTQDQISNIKYHEEF 126 ++ D P+ + K IS++ Y ++ Sbjct: 1273 TMSPDLPQFLQAKCNAYNISDVCYKRDW 1300 Score = 33.5 bits (75), Expect = 0.19 Identities = 17/68 (25%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Query: 57 YPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ 116 +P +T + D + ++ ++ +LQS YK + E +G G+ V + E++++K+ + Sbjct: 3598 HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGW-VPIGSVEVEKVKRAGEI 3656 Query: 117 ISNIKYHE 124 +S+ KY + Sbjct: 3657 LSDRKYRQ 3664 Score = 33.1 bits (74), Expect = 0.25 Identities = 15/81 (18%), Positives = 41/81 (50%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 + + D P+ ++ K + S+ YK + + KG+ + D ++ K + S+++ Sbjct: 1028 YNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQ 1087 Query: 122 YHEEFEKSRMGPSGGEGMEPE 142 Y +++EK++ G + ++ + Sbjct: 1088 YKKDYEKAKGKMVGFQSLQDD 1108 Score = 33.1 bits (74), Expect = 0.25 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Query: 75 KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 K + S +YKE +EK KGK GF + D P+L S+ +Y + +E S+ Sbjct: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASK 1622 Score = 33.1 bits (74), Expect = 0.25 Identities = 49/232 (21%), Positives = 84/232 (36%), Gaps = 32/232 (13%) Query: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 H K FT DT E K + Y E++ K+K V+ DTP++ + Q Sbjct: 1719 HPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDK-TTIHVMPDTPDILLSRVNQI 1777 Query: 116 QISNIKYHEEFEKSRMGPSGGEGMEPE---------RRDSQDGSSYRRPLEQQQPHHI-- 164 +S+ Y +E+ + G + P+ RD Y++ EQ + HI Sbjct: 1778 TMSDKLYKAGWEEEK---KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGF 1834 Query: 165 ------PTSAPVYQQPQQQPVAQSYGGYK----------EPAAPVSIQRSAPGGGGKRYR 208 P Q + Q + GY+ + + V+ ++S YR Sbjct: 1835 RSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYR 1894 Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEA 260 V D +SF+ ++ +Q D+ + + G LP +EA Sbjct: 1895 NVIHTYNMLPDAMSFELAKNMMQIQS-DNQYKADYADFMKGIGWLPLGSLEA 1945 Score = 32.3 bits (72), Expect = 0.43 Identities = 40/171 (23%), Positives = 67/171 (39%), Gaps = 14/171 (8%) Query: 27 KACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVA--DTPENLRLKQQSELQSQV 84 K+ +CET K L+ + K + + Y + + V + P + + + S Sbjct: 645 KSMNYCETPKYQLDTQ-LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDK 703 Query: 85 RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144 YK E+E++KGK + T E + IKK DQ + Y +K++ P Sbjct: 704 SYKAEYEEDKGKCYFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTKFTAVTD---SPVLL 759 Query: 145 DSQDGSSYRRPLEQQQPH-------HIPTSAPVYQQPQQQPVAQSYGGYKE 188 +Q + L + H HIP AP + Q + S YK+ Sbjct: 760 QAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQ 810 Score = 32.3 bits (72), Expect = 0.43 Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 +T + D + ++ K+ ELQS+ YK + E +G G+S + E ++ K+ + IS K Sbjct: 2388 WTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSL-EAEKNKRASEIISEKK 2446 Query: 122 YHEEFEKSR 130 Y + ++++ Sbjct: 2447 YRQPPDRNK 2455 Score = 32.3 bits (72), Expect = 0.43 Identities = 25/112 (22%), Positives = 50/112 (44%), Gaps = 7/112 (6%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIK----KTQ 114 + FT + D + + K ++ +S Y+E ++K+K + ++ DTP++ K T Sbjct: 2453 RNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQ-IHIMPDTPDIVLAKANLINTS 2511 Query: 115 DQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGS--SYRRPLEQQQPHHI 164 D++ + Y E K P ++ + + S Y+ +Q HHI Sbjct: 2512 DKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHI 2563 Score = 32.3 bits (72), Expect = 0.43 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 + D P+ + +++QS YK++FEK K K FS D + KK Q +S++ Y Sbjct: 2811 IRDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYKN 2869 Query: 125 EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 + P + + + D Q + Y+ L+ Sbjct: 2870 YLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQ 2903 Score = 32.0 bits (71), Expect = 0.56 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 + D P+ + +++QS YK++FEK K K FS D + KK Q +S++ Y Sbjct: 2568 IEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYKN 2626 Query: 125 EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 + P + + + D Q + Y+ L+ Sbjct: 2627 YLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQ 2660 Score = 32.0 bits (71), Expect = 0.56 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 10/99 (10%) Query: 33 ETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92 E CK + + K Y + P + FT V D+ E + K + ++ Y E ++K Sbjct: 2919 EKCKRATEILSDKIYRQPP------DRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDK 2972 Query: 93 NKGKGFSVVADTPELQRIKKTQDQISNIKY---HEEFEK 128 +K + ++ DTPE+ ++ + S Y +EE +K Sbjct: 2973 DKTQ-IHIMPDTPEIMLARQNKINYSETLYKLANEEAKK 3010 Score = 32.0 bits (71), Expect = 0.56 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 + D P+ + +++QS YK++FEK K K FS D + KK Q +S++ Y Sbjct: 3054 IEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYKN 3112 Query: 125 EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 + P + + + D Q + Y+ L+ Sbjct: 3113 YLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQ 3146 Score = 32.0 bits (71), Expect = 0.56 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 V D P R + +L Y+ +EKNK K +V D E+ K +Q ++S I Y Sbjct: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMK-IHIVPDMVEMVTAKDSQKKVSEIDY 4813 Score = 31.2 bits (69), Expect = 0.95 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 + D P+ L + ++ QS YKE +EK K K + +TP+ Q + S +Y + Sbjct: 614 INDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMN-YCETPKYQ-LDTQLKNFSEARYKD 671 Query: 125 EFEKSRMGPSGGEGMEP 141 + K +G G +P Sbjct: 672 LYVKDVLGHYVGSMEDP 688 Score = 31.2 bits (69), Expect = 0.95 Identities = 18/76 (23%), Positives = 32/76 (42%), Gaps = 1/76 (1%) Query: 49 KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108 K+ Y + F + D P+ + ++LQS YK+ +E K + D + Sbjct: 1333 KEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK-TSYHTPGDMVSIT 1391 Query: 109 RIKKTQDQISNIKYHE 124 K QD +N+ Y + Sbjct: 1392 AAKMAQDVATNVNYKQ 1407 Score = 31.2 bits (69), Expect = 0.95 Identities = 16/70 (22%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Query: 61 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120 +FT V D + + KQ E+ ++Y++++ K K + +TP L ++ + Sbjct: 4155 NFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK--YTLTETPLLHTAQEAARILDQY 4212 Query: 121 KYHEEFEKSR 130 Y E +E+ + Sbjct: 4213 LYKEGWERQK 4222 Score = 30.8 bits (68), Expect = 1.2 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 6/98 (6%) Query: 38 TLNMKNYKGYEKKPYCNA--HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 T N+KN Y Y A S+ + + T K Q L S ++Y+EE+EK K Sbjct: 4692 TRNLKNL--YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKA 4749 Query: 96 KGF--SVVADTPELQRIKKTQDQISNIKYHEEFEKSRM 131 V D P R + + Y +EK++M Sbjct: 4750 LYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKM 4787 Score = 30.4 bits (67), Expect = 1.6 Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 F + D P+ + Q +++QS YK+ +E K + AD + K Q I+N Sbjct: 2078 FRSLEDDPKLVHSMQVAKMQSDREYKKNYENTK-TSYHTPADMLSVTAAKDAQANITNTN 2136 Query: 122 YHEEFEK 128 Y K Sbjct: 2137 YKHLIHK 2143 Score = 30.4 bits (67), Expect = 1.6 Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Query: 57 YPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ 116 +P + + D + + ++ +LQS YK + E KG G+ V D+ E+ R K+ + Sbjct: 3355 HPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGW-VPIDSLEVVRAKRAGEL 3413 Query: 117 ISNIKYHEEFE 127 +S+ Y + E Sbjct: 3414 LSDTIYRQRPE 3424 Score = 30.4 bits (67), Expect = 1.6 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 79 ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 +LQS YK + G+ + DTP + IK T+ S KY E +E ++ Sbjct: 4943 KLQSSNLYKTSL-RTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTK 4993 Score = 30.0 bits (66), Expect = 2.1 Identities = 16/41 (39%), Positives = 21/41 (51%) Query: 104 TPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144 TP + +K QD S KY E+FEK++ P PE R Sbjct: 83 TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELR 123 Score = 30.0 bits (66), Expect = 2.1 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 V D P+ + +++QS YK++FEK K + +S D + KK Q +S++ Y Sbjct: 3297 VHDDPKIMWSLHIAKVQSDREYKKDFEKYKTR-YSSPVDMLGIVLAKKCQTLVSDVDYKH 3355 Query: 125 EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 + P + + + D Q + Y+ LE Sbjct: 3356 PLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLE 3389 Score = 30.0 bits (66), Expect = 2.1 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 15/84 (17%) Query: 32 CETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 C+T ++ +NY +T + D + ++ K+ +LQS YK + E Sbjct: 3830 CQTLVTDIDYRNYL--------------HEWTCMPDQNDIIQAKKAYDLQSDALYKADLE 3875 Query: 92 KNKGKGFSVVADTPELQRIKKTQD 115 +G G+ + +PE+ R+K Q+ Sbjct: 3876 WLRGIGW-MPQGSPEVLRVKNAQN 3898 Score = 30.0 bits (66), Expect = 2.1 Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K +T+ +TP ++ + + Q YKE +E+ K G+ + D D S Sbjct: 4188 KSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQS 4246 Query: 119 NIKYHEEFEKSR 130 +KY E K + Sbjct: 4247 ELKYKAEHVKQK 4258 Score = 29.6 bits (65), Expect = 2.8 Identities = 30/130 (23%), Positives = 49/130 (37%), Gaps = 4/130 (3%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 +T + D + ++ K+ ELQS YK + E +G G+ + D+ + K D S K Sbjct: 4088 WTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGW-MPNDSVSVNHAKHAADIFSEKK 4146 Query: 122 YHEEFEKSRMGPSGGEGMEPERRDS---QDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQP 178 Y + E P + S D YR+ + + T P+ Q+ Sbjct: 4147 YRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLHTAQEAA 4206 Query: 179 VAQSYGGYKE 188 YKE Sbjct: 4207 RILDQYLYKE 4216 Score = 28.9 bits (63), Expect = 4.7 Identities = 15/58 (25%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Query: 75 KQQSELQSQVRYKEEFEKNKGKGFS--VVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 K + S+++YKE +EK KG + V+ + P + Q S + Y + +E ++ Sbjct: 4484 KHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTK 4541 Score = 28.5 bits (62), Expect = 6.2 Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 14/110 (12%) Query: 25 WHKAC-------FHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQ 77 W K C E K ++ N K Y + P FT + D P ++ K Sbjct: 955 WMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHP------DTLKFTSIEDAPITVQSKIN 1008 Query: 78 SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 +S + YK + E+ K +++ D P+ + K IS Y + + Sbjct: 1009 QAQRSDIAYKAKGEEIIHK-YNLPPDLPQFIQAKVNAYNISENMYKADLK 1057 >gi|5453758 nebulette sarcomeric isoform [Homo sapiens] Length = 1014 Score = 120 bits (302), Expect = 9e-28 Identities = 92/285 (32%), Positives = 128/285 (44%), Gaps = 60/285 (21%) Query: 34 TCKMTLNMKNYKGYEKKPYCNAHYP-KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92 T +M KN + Y H K +++ DTP +K+ S V+Y E+FEK Sbjct: 732 TPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEK 791 Query: 93 NKGKGFS----------------VVADT------PELQRIKKTQDQISNIK--------- 121 KG+GF+ VV+D P + + + I ++K Sbjct: 792 TKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSI 851 Query: 122 ------------------------YHEEFEKSRMGPSGGEGMEPERRD-SQDGSSYRRPL 156 Y + +S + G G+ +R + S+ S+ Sbjct: 852 FDLDPLEDNIQSRSLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCS 911 Query: 157 EQQQPHHIPTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAA 216 E +P APV QQ +Q YG Y + S++ + YRA+YDYSA Sbjct: 912 EVTRPSD--EGAPVLPGAYQQSHSQGYG-YMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQ 968 Query: 217 DEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 DEDEVSF+DGD IVNVQ IDDGWMYGTV+RTG TGMLPANY+E + Sbjct: 969 DEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 1013 Score = 60.5 bits (145), Expect = 1e-09 Identities = 33/69 (47%), Positives = 40/69 (57%) Query: 66 ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 AD E+L K + LQSQV+YKEE+EKNKGK +TP Q K+ Q S Y E+ Sbjct: 319 ADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKED 378 Query: 126 FEKSRMGPS 134 FEK G S Sbjct: 379 FEKEIKGRS 387 Score = 60.5 bits (145), Expect = 1e-09 Identities = 34/95 (35%), Positives = 57/95 (60%), Gaps = 8/95 (8%) Query: 49 KKPYCNAHYPKQ--SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106 +K N +Y Q T ++ TPE R+K+ E S V+Y ++ ++ KG+ S++ DTP Sbjct: 711 QKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRP-SLILDTPA 769 Query: 107 LQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEP 141 ++ +K+ Q+ IS +KYHE+FEK++ G G P Sbjct: 770 MRHVKEAQNHISMVKYHEDFEKTK-----GRGFTP 799 Score = 52.4 bits (124), Expect = 4e-07 Identities = 28/67 (41%), Positives = 43/67 (64%), Gaps = 5/67 (7%) Query: 61 SFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNI 120 +++ +ADTPE R+K + S V YK+E G G + V D+PE++R+KK Q IS++ Sbjct: 570 NYSTIADTPEIQRIKTTQQNISAVFYKKEV----GAG-TAVKDSPEIERVKKNQQNISSV 624 Query: 121 KYHEEFE 127 KY EE + Sbjct: 625 KYKEEIK 631 Score = 51.2 bits (121), Expect = 9e-07 Identities = 27/67 (40%), Positives = 42/67 (62%), Gaps = 5/67 (7%) Query: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 T V D+PE R+K+ + S V+YKEE K + ++D PEL+R+K+ Q ISN++Y Sbjct: 603 TAVKDSPEIERVKKNQQNISSVKYKEEI-----KHATAISDPPELKRVKENQKNISNLQY 657 Query: 123 HEEFEKS 129 E+ K+ Sbjct: 658 KEQNYKA 664 Score = 50.1 bits (118), Expect = 2e-06 Identities = 27/63 (42%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Query: 67 DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 DT + R K+ SE+ SQ +YK++ E KGKG V D P++ R K+T + S KY +E Sbjct: 504 DTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDE 563 Query: 126 FEK 128 EK Sbjct: 564 AEK 566 Score = 48.5 bits (114), Expect = 6e-06 Identities = 33/114 (28%), Positives = 61/114 (53%), Gaps = 8/114 (7%) Query: 49 KKPYCNAHYPKQSF--TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106 +K N Y +Q++ T V+ TPE R+++ E S V+YK E ++ + ++D PE Sbjct: 649 QKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGELQRG-----TAISDPPE 703 Query: 107 LQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQ 160 L+R K+ Q ISN+ Y + ++ E ME +++ ++ SS + + +Q Sbjct: 704 LKRAKENQKNISNVYYRGQLGRATTLSVTPE-MERVKKNQENISSVKYTQDHKQ 756 Score = 45.4 bits (106), Expect = 5e-05 Identities = 22/66 (33%), Positives = 42/66 (63%), Gaps = 5/66 (7%) Query: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 T ++D PE R+K+ + S ++YKE+ K + V+ TPE++R+++ Q+Q+S +KY Sbjct: 634 TAISDPPELKRVKENQKNISNLQYKEQNYKA-----TPVSMTPEIERVRRNQEQLSAVKY 688 Query: 123 HEEFEK 128 E ++ Sbjct: 689 KGELQR 694 Score = 43.5 bits (101), Expect = 2e-04 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 1/67 (1%) Query: 67 DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 DT E K+ +E+ S+ YK + E KGKG V DT ++QR KK + S +Y ++ Sbjct: 467 DTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKD 526 Query: 126 FEKSRMG 132 E G Sbjct: 527 LENEIKG 533 Score = 39.3 bits (90), Expect = 0.003 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 8/100 (8%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126 TPE L +K + L + YK++ E KGKG + ++ ++QR K+ + S +Y ++ Sbjct: 394 TPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDL 453 Query: 127 EKSRMGPSGGEG-----MEPERRDSQDGS--SYRRPLEQQ 159 E G G M+ ++ ++ S Y+R LE + Sbjct: 454 ESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETE 493 Score = 38.5 bits (88), Expect = 0.006 Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 1/45 (2%) Query: 78 SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 +EL S +RYKEEF+K+K K + V D+P L +K IS KY Sbjct: 46 TELISDIRYKEEFKKSKDK-CTFVTDSPMLNHVKNIGAFISEAKY 89 Score = 38.1 bits (87), Expect = 0.008 Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 73 RLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM 131 R K+ SE+ S+ YK++ E KGKG DT E+Q KK + S Y + E Sbjct: 436 RAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIK 495 Query: 132 G 132 G Sbjct: 496 G 496 Score = 35.8 bits (81), Expect = 0.039 Identities = 22/98 (22%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Query: 31 HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90 H + ++ YKG K N+ Y + T+ +++ + ++LQS+V YK++ Sbjct: 76 HVKNIGAFISEAKYKGTIKADLSNSLYKRMPATI-----DSVFAGEVTQLQSEVAYKQKH 130 Query: 91 EKNKG-KGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 + KG ++ + + PE++ + SNI Y ++ + Sbjct: 131 DAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQ 168 Score = 29.6 bits (65), Expect = 2.8 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 12/69 (17%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 F + D E ++ ++ + QV YK V + ++ +K + IS+I+ Sbjct: 6 FEDIKDETEEEKIGEEENEEDQVFYKP------------VIEDLSMELARKCTELISDIR 53 Query: 122 YHEEFEKSR 130 Y EEF+KS+ Sbjct: 54 YKEEFKKSK 62 Score = 28.9 bits (63), Expect = 4.7 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 15/149 (10%) Query: 54 NAHYPKQSFTM-----VADTPENLRLKQQSELQSQVRYKEEFE---KNKGKGFSVVADTP 105 NA Y K M V P+ + S+L SQ++YKE+F+ K+K ++ + ++ Sbjct: 194 NAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPL-ESA 252 Query: 106 ELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGM-----EPERRDSQDGSSYRRPLEQQQ 160 ++ + SN+KY ++ + S + + G Y++ E+ + Sbjct: 253 SFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENK 312 Query: 161 -PHHIPTSAPVYQQPQQQPVAQSYGGYKE 188 +H A + + V QS YKE Sbjct: 313 GMYHFDADAVEHLHHKGNAVLQSQVKYKE 341 >gi|46049092 nebulin-related anchoring protein isoform C [Homo sapiens] Length = 1695 Score = 105 bits (263), Expect = 3e-23 Identities = 46/91 (50%), Positives = 64/91 (70%), Gaps = 1/91 (1%) Query: 5 CARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFT 63 C+RCG VYP EK++C+D+ WHKACFHCE CKM L++ N+ ++KKPYC+AH PK +FT Sbjct: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65 Query: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNK 94 V TP NL ++ E S + +E+ E+ K Sbjct: 66 SVYHTPLNLNVRTFPEAISGIHDQEDGEQCK 96 Score = 70.1 bits (170), Expect = 2e-12 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 F+ V DTPE LR K ++LQS VRY E++E+ +GKG TP Q K+ + S+++ Sbjct: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263 Query: 122 YHEEFEKSRMGPS----GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQ 177 YH++++K G + G EG+ Q G Y E+ + H S P P Q Sbjct: 264 YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYP---EEYEEHRGKGSFPAMITPAYQ 320 Query: 178 PVAQSY 183 +++ Sbjct: 321 NAKKAH 326 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 9/93 (9%) Query: 39 LNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG 97 L+ NY+ YEK K ++T+ D P+ ++ K ++L S+V+YKE +EK KGKG Sbjct: 472 LSHVNYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKG 523 Query: 98 FSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 F + D L K + + SNIKY EE+EK++ Sbjct: 524 FEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556 Score = 51.2 bits (121), Expect = 9e-07 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 9/140 (6%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K +T AD PE L K + S+ RYKE + K + G+ + D Q K + + IS Sbjct: 967 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1026 Query: 119 NIKYHEEFEKSRMGPSGGEGMEPE--------RRDSQDGSSYRRPLEQQQPH-HIPTSAP 169 + KY E FEK + G +E + Q +Y++ E + H+P Sbjct: 1027 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1086 Query: 170 VYQQPQQQPVAQSYGGYKEP 189 ++ S YK P Sbjct: 1087 ALVHAKKAQTLASNQDYKHP 1106 Score = 48.5 bits (114), Expect = 6e-06 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K ++ V DTP+ ++ K ++ S V Y+ ++EKNK +++ D P+L + K S Sbjct: 450 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 508 Query: 119 NIKYHEEFEKSRMGPSGGEGME 140 +KY E +EK++ G+G E Sbjct: 509 EVKYKEGWEKTK-----GKGFE 525 Score = 46.2 bits (108), Expect = 3e-05 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 TP R K+ ++L SQV YK ++ + FS V DTPEL R K S+++Y E++E Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233 Query: 128 KSR 130 + R Sbjct: 234 QQR 236 Score = 43.5 bits (101), Expect = 2e-04 Identities = 22/69 (31%), Positives = 36/69 (52%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 +T+ D P L+ + + S+ YK +E K KGF + D+ K +D S +K Sbjct: 727 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 786 Query: 122 YHEEFEKSR 130 Y E++E+SR Sbjct: 787 YKEDYERSR 795 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Query: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 K+ +K +G+EK + F M D L K EL S ++YKEE+EK KG Sbjct: 505 KLFSEVKYKEGWEKTK-------GKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 557 Query: 96 KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 K AD+ L ++ + S ++Y + FE+S+ Sbjct: 558 KAMG-TADSRLLHSLQIAK-MSSEVEYKKGFEESK 590 Score = 41.2 bits (95), Expect = 0.001 Identities = 18/45 (40%), Positives = 27/45 (60%) Query: 86 YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Y EE+E+++GKG TP Q KK + S+IKY ++F K + Sbjct: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMK 342 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 + +TM PE +R K + S RYKE + + +G+ + + Q + + D S Sbjct: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269 Query: 119 NIKYHEEFEKSRMGPSGGEGMEPERR--------DSQDGSSYRR-PLEQQQPHHIP 165 + Y +F K R G + + + R Q YRR Q H+P Sbjct: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1325 Score = 37.7 bits (86), Expect = 0.010 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG--FSVVA-DTPELQRIKK 112 H K SF + TP K+ EL S ++Y+++F K KG S+ A D L++ + Sbjct: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363 Query: 113 TQDQISNIKYHEEFEKSRMGPSGGEGME 140 +S KY E ++ G G GM+ Sbjct: 364 VNKLVSENKYKENYQNHMRGRYEGVGMD 391 Score = 36.6 bits (83), Expect = 0.023 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 79 ELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM---GP 133 E+ S RYKE F +++G G+ V D P ++ S+ +Y ++F KSR Sbjct: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568 Query: 134 SGGEGMEPERRDSQDGSS--YRRPLEQ 158 + G+ +R Q S YR+PL Q Sbjct: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQ 1595 Score = 35.4 bits (80), Expect = 0.050 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 4/60 (6%) Query: 69 PENLRL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 PE+L++ K+ LQS++RYK + KG G+ + +P+++ KK + IS KY ++ Sbjct: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1415 Score = 34.3 bits (77), Expect = 0.11 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Query: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117 + F + D+ L K + +L S+V+YKE++E+++GK G V ++ + Sbjct: 761 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 820 Query: 118 SNIKYHEEFEKSR 130 S ++Y + FE ++ Sbjct: 821 SELEYKKGFEDTK 833 Score = 33.9 bits (76), Expect = 0.15 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 H FT + DTPE ++ + Y+E+ E K ++ AD PE+ K Sbjct: 929 HPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-YTPTADLPEVLLAKLNAM 987 Query: 116 QISNIKYHEEFEKSRMG 132 IS +Y E + K R G Sbjct: 988 NISETRYKESWSKLRDG 1004 Score = 33.5 bits (75), Expect = 0.19 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 + V D P LQS YK++F K++ + F D P L + K++Q S++ Sbjct: 1530 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1588 Query: 122 YHEEFEKSRMGP 133 Y + + P Sbjct: 1589 YRQPLPQPTCDP 1600 Score = 32.7 bits (73), Expect = 0.33 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 69 PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HEE 125 PE +R+ + + + Y E++E+ +GKG TP QR KK S ++Y H+E Sbjct: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 Score = 31.6 bits (70), Expect = 0.73 Identities = 38/182 (20%), Positives = 77/182 (42%), Gaps = 28/182 (15%) Query: 33 ETCKMTLNMKNYKGYEKKP--------YCNAHYPKQSFTMVADT------------PENL 72 + KM+ ++ KG+E+ N + K++ T+ +D PE++ Sbjct: 572 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 631 Query: 73 RL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 + K+ LQS+++YK + KG G+ + + L++ KK +S Y + ++ Sbjct: 632 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 690 Query: 130 RM-GPSGGEGMEPERR--DSQDGSSYRRPLEQQ-QPHHIPTSAPVYQQPQQQPVAQSYGG 185 + + ME ++ + Q G +Y+ EQ + I P++ Q + S Sbjct: 691 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 750 Query: 186 YK 187 YK Sbjct: 751 YK 752 Score = 31.6 bits (70), Expect = 0.73 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 +T V DTP L K +++ ++ YK E + + +++ PE R K +S+ + Sbjct: 1178 YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHE-YTMTLGLPEFIRAKTNAANLSDAR 1236 Query: 122 YHEEFEKSR 130 Y E + R Sbjct: 1237 YKESWRNLR 1245 Score = 28.1 bits (61), Expect = 8.1 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 76 QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 Q S+LQS++ YK+ FE K + V D L +K Q +++ Y Sbjct: 815 QMSKLQSELEYKKGFEDTKSQ-CHVSLDMVHLVHARKAQHLATDVGY 860 >gi|46049105 nebulin-related anchoring protein isoform S [Homo sapiens] Length = 1730 Score = 105 bits (263), Expect = 3e-23 Identities = 46/91 (50%), Positives = 64/91 (70%), Gaps = 1/91 (1%) Query: 5 CARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFT 63 C+RCG VYP EK++C+D+ WHKACFHCE CKM L++ N+ ++KKPYC+AH PK +FT Sbjct: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65 Query: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNK 94 V TP NL ++ E S + +E+ E+ K Sbjct: 66 SVYHTPLNLNVRTFPEAISGIHDQEDGEQCK 96 Score = 70.1 bits (170), Expect = 2e-12 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 F+ V DTPE LR K ++LQS VRY E++E+ +GKG TP Q K+ + S+++ Sbjct: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263 Query: 122 YHEEFEKSRMGPS----GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQ 177 YH++++K G + G EG+ Q G Y E+ + H S P P Q Sbjct: 264 YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYP---EEYEEHRGKGSFPAMITPAYQ 320 Query: 178 PVAQSY 183 +++ Sbjct: 321 NAKKAH 326 Score = 64.3 bits (155), Expect = 1e-10 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 9/93 (9%) Query: 39 LNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG 97 L+ NY+ YEK K ++T+ D P+ ++ K ++L S+V+YKE +EK KGKG Sbjct: 507 LSHVNYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKG 558 Query: 98 FSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 F + D L K + + SNIKY EE+EK++ Sbjct: 559 FEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591 Score = 51.2 bits (121), Expect = 9e-07 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 9/140 (6%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K +T AD PE L K + S+ RYKE + K + G+ + D Q K + + IS Sbjct: 1002 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061 Query: 119 NIKYHEEFEKSRMGPSGGEGMEPE--------RRDSQDGSSYRRPLEQQQPH-HIPTSAP 169 + KY E FEK + G +E + Q +Y++ E + H+P Sbjct: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1121 Query: 170 VYQQPQQQPVAQSYGGYKEP 189 ++ S YK P Sbjct: 1122 ALVHAKKAQTLASNQDYKHP 1141 Score = 48.5 bits (114), Expect = 6e-06 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 K ++ V DTP+ ++ K ++ S V Y+ ++EKNK +++ D P+L + K S Sbjct: 485 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 543 Query: 119 NIKYHEEFEKSRMGPSGGEGME 140 +KY E +EK++ G+G E Sbjct: 544 EVKYKEGWEKTK-----GKGFE 560 Score = 46.2 bits (108), Expect = 3e-05 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 TP R K+ ++L SQV YK ++ + FS V DTPEL R K S+++Y E++E Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233 Query: 128 KSR 130 + R Sbjct: 234 QQR 236 Score = 43.5 bits (101), Expect = 2e-04 Identities = 22/69 (31%), Positives = 36/69 (52%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 +T+ D P L+ + + S+ YK +E K KGF + D+ K +D S +K Sbjct: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821 Query: 122 YHEEFEKSR 130 Y E++E+SR Sbjct: 822 YKEDYERSR 830 Score = 43.1 bits (100), Expect = 2e-04 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Query: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 K+ +K +G+EK + F M D L K EL S ++YKEE+EK KG Sbjct: 540 KLFSEVKYKEGWEKTK-------GKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 592 Query: 96 KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 K AD+ L ++ + S ++Y + FE+S+ Sbjct: 593 KAMG-TADSRLLHSLQIAK-MSSEVEYKKGFEESK 625 Score = 41.2 bits (95), Expect = 0.001 Identities = 18/45 (40%), Positives = 27/45 (60%) Query: 86 YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Y EE+E+++GKG TP Q KK + S+IKY ++F K + Sbjct: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMK 342 Score = 40.8 bits (94), Expect = 0.001 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 4/74 (5%) Query: 70 ENLRLKQQ---SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126 +NL LKQ ++L S+V YK++ E ++G + +TP+ + + K S+ KY E + Sbjct: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINY-CETPQFRNVSKISKFTSDNKYKENY 412 Query: 127 EKSRMGPSGGEGME 140 + G G GM+ Sbjct: 413 QNHMRGRYEGVGMD 426 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%) Query: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 + +TM PE +R K + S RYKE + + +G+ + + Q + + D S Sbjct: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304 Query: 119 NIKYHEEFEKSRMGPSGGEGMEPERR--------DSQDGSSYRR-PLEQQQPHHIP 165 + Y +F K R G + + + R Q YRR Q H+P Sbjct: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1360 Score = 36.6 bits (83), Expect = 0.023 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 79 ELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM---GP 133 E+ S RYKE F +++G G+ V D P ++ S+ +Y ++F KSR Sbjct: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603 Query: 134 SGGEGMEPERRDSQDGSS--YRRPLEQ 158 + G+ +R Q S YR+PL Q Sbjct: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQ 1630 Score = 35.8 bits (81), Expect = 0.039 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 4/78 (5%) Query: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG--FSVVA-DTPELQRIKK 112 H K SF + TP K+ EL S ++Y+++F K KG S+ A D L++ + Sbjct: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363 Query: 113 TQDQISNIKYHEEFEKSR 130 +S ++Y ++ E SR Sbjct: 364 VNKLVSEVEYKKDLESSR 381 Score = 35.4 bits (80), Expect = 0.050 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 4/60 (6%) Query: 69 PENLRL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 PE+L++ K+ LQS++RYK + KG G+ + +P+++ KK + IS KY ++ Sbjct: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1450 Score = 34.3 bits (77), Expect = 0.11 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Query: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117 + F + D+ L K + +L S+V+YKE++E+++GK G V ++ + Sbjct: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855 Query: 118 SNIKYHEEFEKSR 130 S ++Y + FE ++ Sbjct: 856 SELEYKKGFEDTK 868 Score = 33.9 bits (76), Expect = 0.15 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 H FT + DTPE ++ + Y+E+ E K ++ AD PE+ K Sbjct: 964 HPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-YTPTADLPEVLLAKLNAM 1022 Query: 116 QISNIKYHEEFEKSRMG 132 IS +Y E + K R G Sbjct: 1023 NISETRYKESWSKLRDG 1039 Score = 33.5 bits (75), Expect = 0.19 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 + V D P LQS YK++F K++ + F D P L + K++Q S++ Sbjct: 1565 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1623 Query: 122 YHEEFEKSRMGP 133 Y + + P Sbjct: 1624 YRQPLPQPTCDP 1635 Score = 32.7 bits (73), Expect = 0.33 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 69 PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HEE 125 PE +R+ + + + Y E++E+ +GKG TP QR KK S ++Y H+E Sbjct: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 Score = 31.6 bits (70), Expect = 0.73 Identities = 38/182 (20%), Positives = 77/182 (42%), Gaps = 28/182 (15%) Query: 33 ETCKMTLNMKNYKGYEKKP--------YCNAHYPKQSFTMVADT------------PENL 72 + KM+ ++ KG+E+ N + K++ T+ +D PE++ Sbjct: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 666 Query: 73 RL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 + K+ LQS+++YK + KG G+ + + L++ KK +S Y + ++ Sbjct: 667 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725 Query: 130 RM-GPSGGEGMEPERR--DSQDGSSYRRPLEQQ-QPHHIPTSAPVYQQPQQQPVAQSYGG 185 + + ME ++ + Q G +Y+ EQ + I P++ Q + S Sbjct: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785 Query: 186 YK 187 YK Sbjct: 786 YK 787 Score = 31.6 bits (70), Expect = 0.73 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 +T V DTP L K +++ ++ YK E + + +++ PE R K +S+ + Sbjct: 1213 YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHE-YTMTLGLPEFIRAKTNAANLSDAR 1271 Query: 122 YHEEFEKSR 130 Y E + R Sbjct: 1272 YKESWRNLR 1280 Score = 28.1 bits (61), Expect = 8.1 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 76 QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 Q S+LQS++ YK+ FE K + V D L +K Q +++ Y Sbjct: 850 QMSKLQSELEYKKGFEDTKSQ-CHVSLDMVHLVHARKAQHLATDVGY 895 >gi|20357552 cortactin isoform a [Homo sapiens] Length = 550 Score = 66.2 bits (160), Expect = 3e-11 Identities = 57/203 (28%), Positives = 88/203 (43%), Gaps = 33/203 (16%) Query: 66 ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 A+ R+ ++ + Q + R K E + V+ P+ T++++ + +E+ Sbjct: 369 AEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQ-----PTEERLPSSPVYED 423 Query: 126 F-----EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQ---PQQQ 177 E S GP G EPE S + + YR QQ + + VY+ P Sbjct: 424 AASFKAELSYRGPVSGT--EPEPVYSMEAADYREASSQQGLAY--ATEAVYESAEAPGHY 479 Query: 178 PVAQS-YGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQID 236 P S Y Y+ ++ A+YDY AA +DE+SF D I N++ ID Sbjct: 480 PAEDSTYDEYENDLGITAV-------------ALYDYQAAGDDEISFDPDDIITNIEMID 526 Query: 237 DGWMYGTVERTGDTGMLPANYVE 259 DGW G + G G+ PANYVE Sbjct: 527 DGWWRGVCK--GRYGLFPANYVE 547 >gi|20357556 cortactin isoform b [Homo sapiens] Length = 513 Score = 66.2 bits (160), Expect = 3e-11 Identities = 57/203 (28%), Positives = 88/203 (43%), Gaps = 33/203 (16%) Query: 66 ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 A+ R+ ++ + Q + R K E + V+ P+ T++++ + +E+ Sbjct: 332 AEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQ-----PTEERLPSSPVYED 386 Query: 126 F-----EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQ---PQQQ 177 E S GP G EPE S + + YR QQ + + VY+ P Sbjct: 387 AASFKAELSYRGPVSGT--EPEPVYSMEAADYREASSQQGLAY--ATEAVYESAEAPGHY 442 Query: 178 PVAQS-YGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQID 236 P S Y Y+ ++ A+YDY AA +DE+SF D I N++ ID Sbjct: 443 PAEDSTYDEYENDLGITAV-------------ALYDYQAAGDDEISFDPDDIITNIEMID 489 Query: 237 DGWMYGTVERTGDTGMLPANYVE 259 DGW G + G G+ PANYVE Sbjct: 490 DGWWRGVCK--GRYGLFPANYVE 510 >gi|21361670 drebrin-like isoform a [Homo sapiens] Length = 431 Score = 64.3 bits (155), Expect = 1e-10 Identities = 61/207 (29%), Positives = 86/207 (41%), Gaps = 21/207 (10%) Query: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF- 126 +P++ +QQ E+ S+ R ++E + + F I Q K F Sbjct: 232 SPQSRTWEQQQEVVSRNRNEQESAVHPREIFKQKERAMSTTSISSPQPG----KLRSPFL 287 Query: 127 EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT-----SAPVYQQPQQQ---- 177 +K P G EP S+ + P E+ P P VY++P +Q Sbjct: 288 QKQLTQPETHFGREPAAAISRPRADL--PAEEPAPSTPPCLVQAEEEAVYEEPPEQETFY 345 Query: 178 ---PVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQ 234 P+ Q G E IQ G G RA+YDY AAD+ E+SF + I ++ Sbjct: 346 EQPPLVQQQGAGSEHIDH-HIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEV 404 Query: 235 IDDGWMYGTVERTGDTGMLPANYVEAI 261 ID+GW G G GM PANYVE I Sbjct: 405 IDEGWWRG-YGPDGHFGMFPANYVELI 430 >gi|62198235 drebrin-like isoform b [Homo sapiens] Length = 430 Score = 62.8 bits (151), Expect = 3e-10 Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 27/199 (13%) Query: 75 KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPS 134 + ++E +S V +E F++ + + +P+ +++ +K P Sbjct: 246 RNRNEQESAVHPREIFKQKERAMSTTSISSPQPGKLRSPF-----------LQKQLTQPE 294 Query: 135 GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT-----SAPVYQQPQQQ-------PVAQS 182 G EP S+ + P E+ P P VY++P +Q P+ Q Sbjct: 295 THFGREPAAAISRPRADL--PAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPLVQQ 352 Query: 183 YGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYG 242 G E IQ G G RA+YDY AAD+ E+SF + I ++ ID+GW G Sbjct: 353 QGAGSEHIDH-HIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG 411 Query: 243 TVERTGDTGMLPANYVEAI 261 G GM PANYVE I Sbjct: 412 -YGPDGHFGMFPANYVELI 429 >gi|171906575 drebrin-like isoform c [Homo sapiens] Length = 439 Score = 62.4 bits (150), Expect = 4e-10 Identities = 49/147 (33%), Positives = 64/147 (43%), Gaps = 16/147 (10%) Query: 127 EKSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT-----SAPVYQQPQQQ---- 177 +K P G EP S+ + P E+ P P VY++P +Q Sbjct: 296 QKQLTQPETHFGREPAAAISRPRADL--PAEEPAPSTPPCLVQAEEEAVYEEPPEQETFY 353 Query: 178 ---PVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQ 234 P+ Q G E IQ G G RA+YDY AAD+ E+SF + I ++ Sbjct: 354 EQPPLVQQQGAGSEHIDH-HIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEV 412 Query: 235 IDDGWMYGTVERTGDTGMLPANYVEAI 261 ID+GW G G GM PANYVE I Sbjct: 413 IDEGWWRG-YGPDGHFGMFPANYVELI 438 >gi|19224660 protein kinase C and casein kinase substrate in neurons 3 [Homo sapiens] Length = 424 Score = 59.7 bits (143), Expect = 3e-09 Identities = 52/194 (26%), Positives = 93/194 (47%), Gaps = 22/194 (11%) Query: 72 LRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM 131 L L Q +L S ++ E ++ +G +D +L+ + T + + + E S Sbjct: 247 LTLHQHLDLSSSEKF-HELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWS-- 303 Query: 132 GPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPT---SAPVYQQPQQQPVAQSYGGYKE 188 ++ +R S+ R P E +PT +AP P Q P + G +E Sbjct: 304 -------LDTQRTISRKEKGGRSPDEVTLTSIVPTRDGTAP----PPQSPGSPGTGQDEE 352 Query: 189 PAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDD-GWMYGTVERT 247 + S +++A G R RA+YDY+ + DE+SF+ G+ ++ + + D+ GW G ++ + Sbjct: 353 WSDEESPRKAATG---VRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQ-S 408 Query: 248 GDTGMLPANYVEAI 261 G G+ PANYVE + Sbjct: 409 GRIGLYPANYVECV 422 >gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo sapiens] Length = 492 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 403 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 461 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 462 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 261 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 312 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 319 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 375 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 376 NRQGIFPVSYVEVV 389 >gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo sapiens] Length = 1004 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 915 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 973 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 974 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1004 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 773 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 824 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 831 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 887 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 888 NRQGIFPVSYVEVV 901 >gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo sapiens] Length = 824 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 735 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 793 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 794 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 593 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 644 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 651 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 707 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 708 NRQGIFPVSYVEVV 721 >gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo sapiens] Length = 661 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 572 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 630 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 631 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 430 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 481 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 488 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 544 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 545 NRQGIFPVSYVEVV 558 >gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo sapiens] Length = 731 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 642 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 700 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 701 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 500 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 551 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 558 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 614 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 615 NRQGIFPVSYVEVV 628 >gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo sapiens] Length = 644 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 555 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 613 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 614 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 413 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 464 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 471 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 527 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 528 NRQGIFPVSYVEVV 541 >gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo sapiens] Length = 671 Score = 58.9 bits (141), Expect = 4e-09 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Query: 165 PTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR---YRAVYDYSAADEDEV 221 PT P Q + + P+ P+ + S+P YRA+Y Y +EDE+ Sbjct: 572 PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDEL 631 Query: 222 SFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 ++GD + +QQ DDGW G RT G P NYV + Sbjct: 632 ELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 671 Score = 45.1 bits (105), Expect = 6e-05 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 11/92 (11%) Query: 170 VYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTI 229 VY + P A + GG PA +R A R +D+ A E++ Q GD + Sbjct: 357 VYPSSTRDPSASNGGG--SPARREEKKRKAA-------RLKFDFQAQSPKELTLQKGDIV 407 Query: 230 VNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++D W+ G E G G+ PANYVE + Sbjct: 408 YIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 437 Score = 40.4 bits (93), Expect = 0.002 Identities = 17/51 (33%), Positives = 31/51 (60%) Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259 A Y + E E+SF+ G+ I ++++++ W G + TG G+ PA+YV+ Sbjct: 461 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 511 >gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo sapiens] Length = 329 Score = 58.9 bits (141), Expect = 4e-09 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Query: 165 PTSAPVYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKR---YRAVYDYSAADEDEV 221 PT P Q + + P+ P+ + S+P YRA+Y Y +EDE+ Sbjct: 230 PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDEL 289 Query: 222 SFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 ++GD + +QQ DDGW G RT G P NYV + Sbjct: 290 ELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 329 Score = 45.1 bits (105), Expect = 6e-05 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 11/92 (11%) Query: 170 VYQQPQQQPVAQSYGGYKEPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTI 229 VY + P A + GG PA +R A R +D+ A E++ Q GD + Sbjct: 15 VYPSSTRDPSASNGGG--SPARREEKKRKAA-------RLKFDFQAQSPKELTLQKGDIV 65 Query: 230 VNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++D W+ G E G G+ PANYVE + Sbjct: 66 YIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 95 Score = 40.4 bits (93), Expect = 0.002 Identities = 17/51 (33%), Positives = 31/51 (60%) Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259 A Y + E E+SF+ G+ I ++++++ W G + TG G+ PA+YV+ Sbjct: 119 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 169 >gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo sapiens] Length = 1100 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 1011 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 1069 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 1070 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1100 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 869 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 920 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 927 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 983 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 984 NRQGIFPVSYVEVV 997 >gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo sapiens] Length = 666 Score = 58.9 bits (141), Expect = 4e-09 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 178 PVAQSYGGYK-------EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIV 230 P+ SY + +P PV + GGG + ++A+Y+Y+ +EDE+ ++ D I Sbjct: 577 PIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGG-EPFQALYNYTPRNEDELELRESDVID 635 Query: 231 NVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +++ DDGW GT RT G P NYV+ + Sbjct: 636 VMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 666 Score = 47.4 bits (111), Expect = 1e-05 Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 +AVYD+ A E+SF+ GDT+ +++ID W G E G G+ P +YVE + Sbjct: 435 KAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHGRVGIFPISYVEKL 486 Score = 42.4 bits (98), Expect = 4e-04 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERT 247 +PA P + PG G+ A Y+++A E+S + GD ++ ++++D W G + T Sbjct: 493 QPARPPP--PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGT 549 Query: 248 GDTGMLPANYVEAI 261 G+ P +YVE + Sbjct: 550 NRQGIFPVSYVEVV 563 >gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] Length = 77 Score = 58.9 bits (141), Expect = 4e-09 Identities = 24/52 (46%), Positives = 29/52 (55%) Query: 3 PNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCN 54 P C +C K VY E+V L K WH+ C CE C TL + +E KPYCN Sbjct: 2 PKCPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCN 53 >gi|109689723 abl interactor 2 [Homo sapiens] Length = 475 Score = 57.8 bits (138), Expect = 1e-08 Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 13/106 (12%) Query: 165 PTSAPVYQQ-PQQQPVAQSYGGYKEPAAPVSIQRS--------APGGGGKRYRAVYDYSA 215 P PV+ + P P + Y +E AA V AP ++ A+YDY+ Sbjct: 369 PVEEPVFDESPPPPPPPEDYE--EEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTK 426 Query: 216 ADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 EDE+SFQ+G I +++ DDGW G + G TG+ P NYVE+I Sbjct: 427 DKEDELSFQEGAIIYVIKKNDDGWYEGVM--NGVTGLFPGNYVESI 470 >gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo sapiens] Length = 1151 Score = 57.0 bits (136), Expect = 2e-08 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Query: 184 GGYKEPAAP---VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240 GG ++P A V+ RS Y+A+Y Y ++DE+ +DGD + +++ DDGW Sbjct: 1069 GGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWF 1128 Query: 241 YGTVERTGDTGMLPANYVEAI 261 GT RT G P NYV+ + Sbjct: 1129 VGTSRRTKQFGTFPGNYVKPL 1149 Score = 40.4 bits (93), Expect = 0.002 Identities = 16/53 (30%), Positives = 31/53 (58%) Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 A ++++ + E+SF+ G+ I ++Q+D+ W G + T G+ P YV+ I Sbjct: 896 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 948 Score = 38.5 bits (88), Expect = 0.006 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 RA +D+ A E+ Q GD + +QID W G E G G+ P Y+E + Sbjct: 821 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 872 >gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo sapiens] Length = 1292 Score = 57.0 bits (136), Expect = 2e-08 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Query: 184 GGYKEPAAP---VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWM 240 GG ++P A V+ RS Y+A+Y Y ++DE+ +DGD + +++ DDGW Sbjct: 1210 GGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWF 1269 Query: 241 YGTVERTGDTGMLPANYVEAI 261 GT RT G P NYV+ + Sbjct: 1270 VGTSRRTKQFGTFPGNYVKPL 1290 Score = 40.4 bits (93), Expect = 0.002 Identities = 16/53 (30%), Positives = 31/53 (58%) Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 A ++++ + E+SF+ G+ I ++Q+D+ W G + T G+ P YV+ I Sbjct: 874 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 926 Score = 38.5 bits (88), Expect = 0.006 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 208 RAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 RA +D+ A E+ Q GD + +QID W G E G G+ P Y+E + Sbjct: 799 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 850 >gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens] Length = 529 Score = 56.6 bits (135), Expect = 2e-08 Identities = 41/136 (30%), Positives = 66/136 (48%), Gaps = 19/136 (13%) Query: 128 KSRMGPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQPVAQSYGGYK 187 +SR G SG G EP+ R + RR L + P+++ +Y Q + S+G Sbjct: 267 RSRHG-SGSYGTEPDARPASQLEPDRRSLPRT-----PSASSLYSGSAQSSRSNSFG--- 317 Query: 188 EPAAPVSIQRSAPGGGGKRYRAVYDYS-AADEDEVSFQDGDTI-VNVQQIDDGWMYGTVE 245 +R GGG +R RA+ +S A+ + F GD + V V + +GW+YG +E Sbjct: 318 --------ERPGGGGGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLE 369 Query: 246 RTGDTGMLPANYVEAI 261 + +G P YV+A+ Sbjct: 370 GSSASGWFPEAYVKAL 385 >gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] Length = 731 Score = 56.2 bits (134), Expect = 3e-08 Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 2/56 (3%) Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259 G++ +A+YD+ +EDE+SF+ GD I ++ +DD WM G E G +G+ P NY++ Sbjct: 673 GRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSG--ELMGKSGIFPKNYIQ 726 Score = 43.5 bits (101), Expect = 2e-04 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%) Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 G R A ++Y +DE+SF +G+ I+ + +++ W G V G TG+ P N+VE + Sbjct: 514 GSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVEPV 569 Score = 34.7 bits (78), Expect = 0.086 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 210 VYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 ++D+ A D+++ G+ + +++ID W G G+ PANYV+ I Sbjct: 444 LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCR--NQIGIFPANYVKVI 493 Score = 32.7 bits (73), Expect = 0.33 Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 2/50 (4%) Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYV 258 A++ ++A D++SF+ GD I ++++D W G ++ G+ PA +V Sbjct: 609 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ--DREGIFPAVFV 656 >gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] Length = 767 Score = 56.2 bits (134), Expect = 3e-08 Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 2/56 (3%) Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259 G++ +A+YD+ +EDE+SF+ GD I ++ +DD WM G E G +G+ P NY++ Sbjct: 709 GRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSG--ELMGKSGIFPKNYIQ 762 Score = 43.5 bits (101), Expect = 2e-04 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%) Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 G R A ++Y +DE+SF +G+ I+ + +++ W G V G TG+ P N+VE + Sbjct: 550 GSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVEPV 605 Score = 34.7 bits (78), Expect = 0.086 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 210 VYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 ++D+ A D+++ G+ + +++ID W G G+ PANYV+ I Sbjct: 480 LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCR--NQIGIFPANYVKVI 529 Score = 32.7 bits (73), Expect = 0.33 Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 2/50 (4%) Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYV 258 A++ ++A D++SF+ GD I ++++D W G ++ G+ PA +V Sbjct: 645 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ--DREGIFPAVFV 692 >gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] Length = 790 Score = 56.2 bits (134), Expect = 3e-08 Identities = 23/56 (41%), Positives = 38/56 (67%), Gaps = 2/56 (3%) Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259 G++ +A+YD+ +EDE+SF+ GD I ++ +DD WM G E G +G+ P NY++ Sbjct: 732 GRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSG--ELMGKSGIFPKNYIQ 785 Score = 43.5 bits (101), Expect = 2e-04 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%) Query: 204 GKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 G R A ++Y +DE+SF +G+ I+ + +++ W G V G TG+ P N+VE + Sbjct: 573 GSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVR--GRTGIFPLNFVEPV 628 Score = 34.7 bits (78), Expect = 0.086 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 210 VYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI 261 ++D+ A D+++ G+ + +++ID W G G+ PANYV+ I Sbjct: 503 LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCR--NQIGIFPANYVKVI 552 Score = 32.7 bits (73), Expect = 0.33 Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 2/50 (4%) Query: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYV 258 A++ ++A D++SF+ GD I ++++D W G ++ G+ PA +V Sbjct: 668 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ--DREGIFPAVFV 715 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.131 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,397,996 Number of Sequences: 37866 Number of extensions: 570778 Number of successful extensions: 2872 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 278 Number of HSP's successfully gapped in prelim test: 158 Number of HSP's that attempted gapping in prelim test: 1886 Number of HSP's gapped (non-prelim): 960 length of query: 261 length of database: 18,247,518 effective HSP length: 100 effective length of query: 161 effective length of database: 14,460,918 effective search space: 2328207798 effective search space used: 2328207798 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.