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Search of human proteins with 52426745
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52426745 Cas-Br-M (murine) ecotropic retroviral transforming
sequence [Homo sapiens]
(906 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52426745 Cas-Br-M (murine) ecotropic retroviral transforming ... 1873 0.0
gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming ... 835 0.0
gi|195927027 Cas-Br-M (murine) ecotropic retroviral transforming... 422 e-118
gi|195927030 Cas-Br-M (murine) ecotropic retroviral transforming... 328 1e-89
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 58 3e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 57 6e-08
gi|47132519 Ras association and pleckstrin homology domains 1 is... 56 1e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 56 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 2e-07
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 55 3e-07
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 55 3e-07
gi|22027541 programmed cell death 7 [Homo sapiens] 54 9e-07
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 53 1e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 53 1e-06
gi|210032580 SET domain containing 1B [Homo sapiens] 53 1e-06
gi|27436925 synoviolin 1 isoform a [Homo sapiens] 52 3e-06
gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transfera... 52 3e-06
gi|5902054 ring finger protein 5 [Homo sapiens] 51 4e-06
gi|27436927 synoviolin 1 isoform b [Homo sapiens] 51 6e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 50 7e-06
gi|209529739 hypothetical protein LOC100132247 [Homo sapiens] 50 7e-06
gi|153792074 proline rich 12 [Homo sapiens] 50 7e-06
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 49 2e-05
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 49 2e-05
gi|110349719 titin isoform N2-A [Homo sapiens] 49 2e-05
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 49 2e-05
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 49 2e-05
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 49 2e-05
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 49 2e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 49 2e-05
>gi|52426745 Cas-Br-M (murine) ecotropic retroviral transforming
sequence [Homo sapiens]
Length = 906
Score = 1873 bits (4852), Expect = 0.0
Identities = 906/906 (100%), Positives = 906/906 (100%)
Query: 1 MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCW 60
MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCW
Sbjct: 1 MAGNVKKSSGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCW 60
Query: 61 KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFME 120
KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFME
Sbjct: 61 KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFME 120
Query: 121 NLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFR 180
NLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFR
Sbjct: 121 NLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFR 180
Query: 181 ITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFE 240
ITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFE
Sbjct: 181 ITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFE 240
Query: 241 FDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRL 300
FDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRL
Sbjct: 241 FDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRL 300
Query: 301 GQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDH 360
GQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDH
Sbjct: 301 GQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDH 360
Query: 361 IKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCR 420
IKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCR
Sbjct: 361 IKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCR 420
Query: 421 CEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVER 480
CEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVER
Sbjct: 421 CEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVER 480
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR
Sbjct: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
Query: 541 DLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPV 600
DLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPV
Sbjct: 541 DLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPV 600
Query: 601 SAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECD 660
SAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECD
Sbjct: 601 SAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECD 660
Query: 661 HPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRAC 720
HPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRAC
Sbjct: 661 HPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRAC 720
Query: 721 DCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPP 780
DCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPP
Sbjct: 721 DCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPP 780
Query: 781 VPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSC 840
VPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSC
Sbjct: 781 VPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSC 840
Query: 841 QQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISS 900
QQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISS
Sbjct: 841 QQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISS 900
Query: 901 PAHVAT 906
PAHVAT
Sbjct: 901 PAHVAT 906
>gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming
sequence b [Homo sapiens]
Length = 982
Score = 835 bits (2156), Expect = 0.0
Identities = 498/1018 (48%), Positives = 598/1018 (58%), Gaps = 184/1018 (18%)
Query: 9 SGAGGGSGSGGSGSGGLIGLMKDAFQPHHHHHHHLSPHPPGTVDKKMVEKCWKLMDKVVR 68
+G G G G ++G++ DA Q + P D++ VEK WKLMDKVVR
Sbjct: 6 NGRNPGGRGGNPRKGRILGII-DAIQDA------VGPPKQAAADRRTVEKTWKLMDKVVR 58
Query: 69 LCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEG--KMETLGENEYFRVFMENLMKKT 126
LCQNPKL LKNSPPYILD+LPDTYQHLR ILS+Y+ K+ L ENEYF++++++LMKK+
Sbjct: 59 LCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKS 118
Query: 127 KQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADA 186
K+ I LFKEGKERMYEE SQ RRNLTKLSLIFSHMLAE+K IFP+G FQGD FRITKADA
Sbjct: 119 KRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADA 178
Query: 187 AEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTR 246
AEFWRK FG+KTIVPWK FRQ LHEVH ISSGLEAMALKSTIDLTCNDYISVFEFDIFTR
Sbjct: 179 AEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTR 238
Query: 247 LFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIG 306
LFQPW S+LRNWN LAVTHPGYMAFLTYDEVKARLQK+ KPGSYIFRLSCTRLGQWAIG
Sbjct: 239 LFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIG 298
Query: 307 YVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQE 366
YVT DGNILQTIPHNKPLFQALIDG REGFYL+PDGR+ NPDLTGLCEPTP DHIKVTQE
Sbjct: 299 YVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQE 358
Query: 367 QYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGT 426
QYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLT+WQES+GQGCPFCRCEIKGT
Sbjct: 359 QYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGT 418
Query: 427 EPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAK--VERPPSP 484
EPI+VDPFDPR GS + P D DDD+ +++L MM LA + +R SP
Sbjct: 419 EPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESL-MMNRLANVRKCTDRQNSP 477
Query: 485 FS------------------MAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGS 526
+ P SLPPVPPRLDL+ + + S G+ +
Sbjct: 478 VTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMV 537
Query: 527 LHKDKPLPVPPT-LRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSR 585
+DKPLP PP LRD PPPPPP+RP + ++R R PSRD PP+P
Sbjct: 538 RKQDKPLPAPPPPLRD-PPPPPPERPPPIPPDNRLSRHIHHVE--SVPSRD--PPMPL-- 590
Query: 586 LGDSWLPRPI----------------PKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQME 629
++W PR + PK ++A S+ + RHS S P M
Sbjct: 591 --EAWCPRDVFGTNQLVGCRLLGEGSPKPGITASSN--------VNGRHSRVGSDPVLMR 640
Query: 630 P--RPDVPRLGSTFSLDTSMSMNSSPLVGPECD-HPKIKPSSSANAIYSLAARPLPVPKL 686
R D+P L+ + ++ L E D P++ P P PV L
Sbjct: 641 KHRRHDLP-------LEGAKVFSNGHLGSEEYDVPPRLSP-------------PPPVTTL 680
Query: 687 PPGEQCEG---------------EEDTEYMTPSSRPLRPLDTSQSS--------RACDCD 723
P +C G E+D EY PSS P+ L++ S R+CD
Sbjct: 681 LPSIKCTGPLANSLSEKTRDPVEEDDDEYKIPSSHPV-SLNSQPSHCHNVKPPVRSCDNG 739
Query: 724 QQIDSCTYEAMYNIQSQAPSIT---ESSTFGEGNLAAAHANTGPEESENEDDG------- 773
+ + T+ +S P ++ + F + P +N G
Sbjct: 740 HCMLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTRDNPKHGSSLNRTP 799
Query: 774 --YD-----------------VPKPPVPA----VLARRTLSDISNASSSFGWLSLDGDPT 810
YD +P PP PA + + S SS L DP
Sbjct: 800 SDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPF 859
Query: 811 TNVTEG---------------------------------SQVPERPPKPFPRRINSERKA 837
++ G SQ P RPPKP PRR E
Sbjct: 860 VDLASGQVPLPPARRLPGENVKTNRTSQDYDQLPSCSDGSQAPARPPKPRPRRTAPEIHH 919
Query: 838 GSCQQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREF 895
++ GP A A + ++I LM +GY+++++++AL IAQNN+E+A++ILREF
Sbjct: 920 ---RKPHGPEA----ALENVDAKIAKLMGEGYAFEEVKRALEIAQNNVEVARSILREF 970
>gi|195927027 Cas-Br-M (murine) ecotropic retroviral transforming
sequence c isoform 1 [Homo sapiens]
Length = 474
Score = 422 bits (1085), Expect = e-118
Identities = 210/449 (46%), Positives = 286/449 (63%), Gaps = 33/449 (7%)
Query: 61 KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYE-----GKMETLGENEYF 115
+++ ++ C +P+L++ SPP + DLLP T Q LR + G G ++
Sbjct: 23 RMLQRLEEQCVDPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFL 80
Query: 116 RVFMENLMKKTKQTISLF-----KEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFP 170
+++ NL K++Q +L + + ++ S+ RR L KL++IFSHM AEL +FP
Sbjct: 81 LIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFP 140
Query: 171 SGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDL 230
G + G +++TKA A FWR++ G + ++PW F L HP+ G A+AL++TIDL
Sbjct: 141 GGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDL 200
Query: 231 TCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGS 290
TC+ ++S+FEFD+FTRLFQPW +LL+NW LAV HPGYMAFLTYDEV+ RLQ KPGS
Sbjct: 201 TCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGS 260
Query: 291 YIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLT 350
YIFR SCTRLGQWAIGYV++DG+ILQTIP NKPL Q L++G ++GFYL+PDG+ NPDLT
Sbjct: 261 YIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLT 320
Query: 351 GLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQE 410
L + PQ I V++EQ +LY M STF+LCKICAE++KDVKIEPCGHL+C+ CL +WQ
Sbjct: 321 ELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQH 380
Query: 411 SEGQGCPFCRCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMM 470
S+ Q CPFCRCEIKG E + + F + + +D + D
Sbjct: 381 SDSQTCPFCRCEIKGWEAVSIYQFHGQATA-----------------EDSGNSSDQEGRE 423
Query: 471 KELAGAKVERPPSPFSMAPQASLPPVPPR 499
EL + PP P P+ LPP PR
Sbjct: 424 LELGQVPLSAPPLP----PRPDLPPRKPR 448
>gi|195927030 Cas-Br-M (murine) ecotropic retroviral transforming
sequence c isoform 2 [Homo sapiens]
Length = 428
Score = 328 bits (841), Expect = 1e-89
Identities = 176/449 (39%), Positives = 245/449 (54%), Gaps = 79/449 (17%)
Query: 61 KLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYE-----GKMETLGENEYF 115
+++ ++ C +P+L++ SPP + DLLP T Q LR + G G ++
Sbjct: 23 RMLQRLEEQCVDPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFL 80
Query: 116 RVFMENLMKKTKQTISLF-----KEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFP 170
+++ NL K++Q +L + + ++ S+ RR L KL++IFSHM AEL +FP
Sbjct: 81 LIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFP 140
Query: 171 SGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDL 230
G + G +++TKA A FWR++ G + ++PW F L HP+ G A+AL++TIDL
Sbjct: 141 GGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDL 200
Query: 231 TCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGS 290
TC+ ++S+FEFD+FTRLFQPW +LL+NW LAV HPGYMAFLTYDEV+ RLQ KPGS
Sbjct: 201 TCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGS 260
Query: 291 YIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLT 350
Y L+PDG+ NPDLT
Sbjct: 261 Y----------------------------------------------LYPDGKTHNPDLT 274
Query: 351 GLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQE 410
L + PQ I V++EQ +LY M STF+LCKICAE++KDVKIEPCGHL+C+ CL +WQ
Sbjct: 275 ELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQH 334
Query: 411 SEGQGCPFCRCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMM 470
S+ Q CPFCRCEIKG E + + F + + +D + D
Sbjct: 335 SDSQTCPFCRCEIKGWEAVSIYQFHGQATA-----------------EDSGNSSDQEGRE 377
Query: 471 KELAGAKVERPPSPFSMAPQASLPPVPPR 499
EL + PP P P+ LPP PR
Sbjct: 378 LELGQVPLSAPPLP----PRPDLPPRKPR 402
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 58.2 bits (139), Expect = 3e-08
Identities = 88/312 (28%), Positives = 113/312 (36%), Gaps = 63/312 (20%)
Query: 481 PPSPFSMAPQASLPP-VPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTL 539
PP+ ++P A+ P PP L P +V P S A S +A+ PL PP
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQV--PPSPPASPPMSPSATPPPQAPPPLAAPPL- 735
Query: 540 RDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVP 599
+PP PP P S A P+ PL P ++PP P + L S L +P P+ P
Sbjct: 736 -QVPPSPPASPPMSPSATPPPRVPPLLAAP-----PLQVPPSPPASLPMSPLAKPPPQAP 789
Query: 600 VSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPEC 659
P+ + P L S P S P Q P S S+ SPL P
Sbjct: 790 ---PALATP----PLQALPSPPASFPGQAPFSP-------------SASLPMSPLATPPP 829
Query: 660 DHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRA 719
P + LAA L VP PP P P DTS S
Sbjct: 830 QAPPV-----------LAAPLLQVPPSPPA-------SPTLQAPRRPPTPGPDTSVSGPR 871
Query: 720 CDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLA--AAHANTGPEESENEDDGYD-- 775
A+ PS + SST +LA ++ A + PEE D G +
Sbjct: 872 LTL----------ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921
Query: 776 -VPKPPVPAVLA 786
PP A LA
Sbjct: 922 AAASPPPDAELA 933
Score = 51.6 bits (122), Expect = 3e-06
Identities = 67/250 (26%), Positives = 89/250 (35%), Gaps = 60/250 (24%)
Query: 473 LAGAKVERPPSPFSMAPQASLPPV-PPRLDLLPQRVCVPSSASALGTASKAASGSLHKDK 531
LA ++ PP+ + P +LP + PP L +ASA T +
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPL----------QTASAPLTTPHLETPPCPAPC 567
Query: 532 PLPVPPTLRDLPPP--------PPPDRPYSVGAE-----SRPQRRPLPCTPGDCPSRDKL 578
PL PP+ PPP PPP P ++ + P PL P P L
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627
Query: 579 PPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGREL-TNRHSLPFSLPSQMEPRPDVPRL 637
PP+ + P P P+S ++ P L + PFS P P P V
Sbjct: 628 PPLQAP-------PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP----PSPPV--- 673
Query: 638 GSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEED 697
S +SP V P P P SLAA PL VP PP
Sbjct: 674 ------QAPFSPPASPPVSPSATPPSQAPP-------SLAAPPLQVPPSPPA-------- 712
Query: 698 TEYMTPSSRP 707
+ M+PS+ P
Sbjct: 713 SPPMSPSATP 722
Score = 48.1 bits (113), Expect = 4e-05
Identities = 105/427 (24%), Positives = 142/427 (33%), Gaps = 95/427 (22%)
Query: 481 PPSPFSMAPQASLPP--VPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPT 538
P P QA PP PPR D P P S+S L T S + + K PVPP
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLATPSPSGT------KARPVPPP 320
Query: 539 LR-------DLPPPPPPDRPYSVGAES---RPQRRPLPCTPGDCPSR------------- 575
LPP PP P + S P + LP P PS+
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Query: 576 ---DKLPP--VPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEP 630
+PP VP S S P P + +S+ ++ L HS P Q +
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSP-LALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439
Query: 631 R-----------PDVPRLGSTFS------LDTSMSMNSSPLVGPECDHPKIKPSSSANAI 673
PD P L + S L TS+S SPL P HP A+
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP-------LQAL 492
Query: 674 YSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEA 733
SLA+ P SS + PL+T S S T
Sbjct: 493 SSLASHSPQAPL------------------SSLIMPPLETQSSLAPPSLQTPPASLTTPP 534
Query: 734 MYNIQSQAPSITESSTFGEGNLAAAHANTGPEES----ENEDDGYDVPKPPVPAVLARRT 789
+ N+ S AP ++++ L H T P + + P P P+ +A
Sbjct: 535 LENLPSLAPPPLQTAS---APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA--- 588
Query: 790 LSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSCQQGSGPAAS 849
+ A + L G P+ + S + PP+ P +A S P +
Sbjct: 589 -TPPPQAPPALASPPLQGLPSPPL---SPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Query: 850 AATASPQ 856
AT SPQ
Sbjct: 645 LATPSPQ 651
Score = 43.9 bits (102), Expect = 7e-04
Identities = 55/171 (32%), Positives = 66/171 (38%), Gaps = 35/171 (20%)
Query: 473 LAGAKVERPPSP---FSMAPQASLPP-VPPRLDLLPQRVCVPSSASALGTASKAASGSLH 528
LA ++ PPSP M+P A PP PP L P + AS G A + S SL
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820
Query: 529 KDKPLPVPP---------TLRDLPPPPP-------PDRPYSVGAESRPQ--RRPLPCTPG 570
PL PP L +PP PP P RP + G ++ R L PG
Sbjct: 821 M-SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
Query: 571 DCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLP 621
PP P SR S L P ++ SSS T EL S P
Sbjct: 880 --------PPPPPSRSPSSTLSGP----DLAGHSSSATSTPEELRGYDSGP 918
Score = 43.5 bits (101), Expect = 9e-04
Identities = 66/255 (25%), Positives = 89/255 (34%), Gaps = 40/255 (15%)
Query: 473 LAGAKVERPPSPFSMAPQASLPP-VPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDK 531
LA ++ PSP ++P A+ PP PP L L P + P S A S A+ S
Sbjct: 598 LASPPLQGLPSP-PLSPLATPPPQAPPXLALPPLQA--PPSPPASPPLSPLATPSPQAPN 654
Query: 532 PLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPV-------PSS 584
L V PPP P + P P P P PP+ S
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
Query: 585 RLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLP--SQMEPRPDVPRLGSTFS 642
+ S P P P++AP P S P S P P P VP L +
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVP---------PSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 643 LDT----SMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDT 698
L S+ SPL P P+ P+ + + +L + P P P
Sbjct: 766 LQVPPSPPASLPMSPLAKPP---PQAPPALATPPLQALPSPPASFPGQAP---------- 812
Query: 699 EYMTPSSRPLRPLDT 713
+ +S P+ PL T
Sbjct: 813 -FSPSASLPMSPLAT 826
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/140 (34%), Positives = 61/140 (43%), Gaps = 27/140 (19%)
Query: 473 LAGAKVERPPSPFS---MAPQASLPP-VPPRLDLLPQRVCVPSSASALGTASKAASGSLH 528
LA ++ PPSP + M+P A+ PP VPP L P + VP S A S A
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ--VPPSPPASLPMSPLAKPPPQ 787
Query: 529 KDKPLPVPPTLRDLPPPP---PPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSR 585
L PP L+ LP PP P P+S A LP +P P + PPV
Sbjct: 788 APPALATPP-LQALPSPPASFPGQAPFSPSAS-------LPMSPLATPP-PQAPPV---- 834
Query: 586 LGDSWLPRPIPKVPVSAPSS 605
L P+ +VP S P+S
Sbjct: 835 -----LAAPLLQVPPSPPAS 849
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 57.4 bits (137), Expect = 6e-08
Identities = 66/259 (25%), Positives = 95/259 (36%), Gaps = 23/259 (8%)
Query: 465 DTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLD--LLPQRVCVPSSASALGTASKA 522
+ L + + L + + PP ++P P P + L P PS A +
Sbjct: 481 EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
Query: 523 ASGSLH---KDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLP 579
+ L ++ PL PP +LP PPP+ + P+ P+ P + P P
Sbjct: 541 EASPLSPPFEESPLSPPP--EELPTSPPPE---ASRLSPPPEESPMSPPPEESPMS---P 592
Query: 580 PVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLP---SQMEPRPDVPR 636
P +SRL + P+ P +P S P R P S P S M P P+V R
Sbjct: 593 PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Query: 637 LGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGE- 695
L L ++ P P P+ P+S L+ P P PP E
Sbjct: 653 LSP---LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
Query: 696 --EDTEYMTP-SSRPLRPL 711
ED+ P PL PL
Sbjct: 710 PPEDSLMSLPLEESPLLPL 728
Score = 52.4 bits (124), Expect = 2e-06
Identities = 60/219 (27%), Positives = 76/219 (34%), Gaps = 29/219 (13%)
Query: 479 ERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPL---PV 535
E P SP S PP RL P+ + AS L A LH +PL P+
Sbjct: 446 ESPLSPPPEESPTSPPPEASRLSPPPEEL----PASPLPEA-------LHLSRPLEESPL 494
Query: 536 PPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPI 595
P + P PPP+ E P P P PP +S L + P+
Sbjct: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL 554
Query: 596 PKVPVSAPSSSDPWTGRELTNRHSLPFSLP---SQMEPRPDVPRLGSTFSLDTSMSMNSS 652
P P+S P R P S P S M P P+ RL F S
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF--------EES 606
Query: 653 PLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQ 691
PL P + P P ++ L+ P P PP E+
Sbjct: 607 PLSPPPEESPLSPPPEASR----LSPPPEDSPMSPPPEE 641
Score = 47.0 bits (110), Expect = 8e-05
Identities = 83/346 (23%), Positives = 120/346 (34%), Gaps = 54/346 (15%)
Query: 479 ERPPSPF---SMAPQASLP-PVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLP 534
E P SP S++PQ P P+PP L + P + S LG D P
Sbjct: 914 ELPLSPSGEPSLSPQLMPPDPLPPPLSPIIT-AAAPPALSPLGELEYPFGAKGDSDPESP 972
Query: 535 VPPTLRDLPPPPPPDR----PYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSW 590
+ + + P PPP+ P V P P P + LPP S L S
Sbjct: 973 LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSL 1032
Query: 591 LPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMN 650
+P+ P S P +LP S+PS + P V + L M
Sbjct: 1033 VPQNSPPSQCSPP---------------ALPLSVPSPLSPIGKVVGVSDEAELH---EME 1074
Query: 651 SSPLVGPECDHPKIKPSSSANAIYSLAARPLPVP----KLPPGEQCEGEEDTEYMTPSSR 706
+ + PEC P ++PS A PLP P P +D + +
Sbjct: 1075 TEKVSEPEC--PALEPS---------ATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTA 1123
Query: 707 PLRPLDTSQSSRACDCDQQIDSCTYE-----AMYNIQSQAPSITESSTFGEGNLAAAHAN 761
PL +D S + Q S E + + + AP +T + E A +
Sbjct: 1124 PLDGIDAPGSQP--EPGQTPGSLASELKGSPVLLDPEELAP-VTPMEVYPECKQTAGQGS 1180
Query: 762 TGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDG 807
P E + E P P P ++ +++ISN S S G
Sbjct: 1181 --PCEEQEEPRAPVAPTP--PTLIKSDIVNEISNLSQGDASASFPG 1222
Score = 45.4 bits (106), Expect = 2e-04
Identities = 72/279 (25%), Positives = 97/279 (34%), Gaps = 51/279 (18%)
Query: 476 AKVERPP--SPFSMAPQASLPPVPP---RLDLLP--QRVCVPSSASALGTASKAASGSLH 528
+++ PP SP S P+ S PP RL LP R+ P S L + + S
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPP 683
Query: 529 KDKPLPVPPTLRDLPPPPPPDRPYSVGAE----SRPQRR----PLPCTPGDCPSRD--KL 578
+ PP PPP D P S E S P PLP P CP + L
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
Query: 579 PPVP-----SSRLGDSWL----------PRP-------IPKVPVSAPSSSDPWTGRELTN 616
P P S R + L P+P +P+ P +P + P +
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803
Query: 617 RHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSL 676
H P + + P P+ P L + P + P + + P L
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSP--------EL 855
Query: 677 AARPL-PVPKLPPGE--QCEGEEDTEYMTPSSRP-LRPL 711
PL P P+ PP E QC E+ P P L PL
Sbjct: 856 EKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPL 894
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/169 (28%), Positives = 65/169 (38%), Gaps = 19/169 (11%)
Query: 527 LHKDKPLPVPPTLRDLPPPP--PPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSS 584
L+++ PL PP L PPP P P + P LP +P P L S
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASP--LPEALHL----SR 487
Query: 585 RLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRP--DVPRLGSTFS 642
L +S L P + P+S P S P++ E P S P + P P + P +
Sbjct: 488 PLEESPLSPPPEESPLSPPPESSPFSPLE-----ESPLSPPEESPPSPALETPLSPPPEA 542
Query: 643 LDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQ 691
S SPL P P+ P+S L+ P P PP E+
Sbjct: 543 SPLSPPFEESPLSPP----PEELPTSPPPEASRLSPPPEESPMSPPPEE 587
Score = 41.2 bits (95), Expect = 0.004
Identities = 61/230 (26%), Positives = 90/230 (39%), Gaps = 35/230 (15%)
Query: 424 KGTEPIVVDP-FDPRGSGSLLRQGAEGAPSPNYDDDD----DERADDTLFMMKELAGAKV 478
K +EP++ P F +++ GA SP+Y + D + T EL V
Sbjct: 2267 KASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDV 2326
Query: 479 ERPPSPFSMAPQAS-LPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLP--- 534
+ P + P+AS + P P L L PQ P A AL A S H D P
Sbjct: 2327 FKAP----LTPRASQVEPQSPGLGLRPQE---PPPAQAL-----APSPPSHPDIFRPGSY 2374
Query: 535 ----VPPTLRDLPPPPPPDRPYSVGAESRPQR--RPLPCTPGDCPSRDKLPPVPSSRLGD 588
P L P PPPP+ ++ S P +P +P S + P P +
Sbjct: 2375 TDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASP-QSQSSSQSPLTPRPLSAE 2433
Query: 589 SWLPRPI-PKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRL 637
++ P P+ P+ S DP++ + PF+ P PRP P +
Sbjct: 2434 AFCPSPVTPRF-----QSPDPYSRPPSRPQSRDPFA-PLHKPPRPQPPEV 2477
Score = 35.4 bits (80), Expect = 0.24
Identities = 54/232 (23%), Positives = 80/232 (34%), Gaps = 40/232 (17%)
Query: 475 GAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLH-KDKPL 533
G + P ++PQ P + P +P+ C+ + ++ L + +
Sbjct: 794 GPHLSPQPEELHLSPQTEEPHLSP----VPEEPCLSPQPEESHLSPQSEEPCLSPRPEES 849
Query: 534 PVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVP-------SSRL 586
+ P L P P P++P P PG CP+ ++LP P S L
Sbjct: 850 HLSPELEKPPLSPRPEKP--------------PEEPGQCPAPEELPLFPPPGEPSLSPLL 895
Query: 587 GDSWLPRP--IPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEP---RPDVPRLGSTF 641
G+ L P P P+ P L+ + P LP + P P L
Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLG 955
Query: 642 SLDTSM-----SMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPP 688
L+ S SPL P + P I P AN P+P LPP
Sbjct: 956 ELEYPFGAKGDSDPESPLAAPILETP-ISPPPEANC---TDPEPVPPMILPP 1003
Score = 34.7 bits (78), Expect = 0.41
Identities = 32/123 (26%), Positives = 48/123 (39%), Gaps = 22/123 (17%)
Query: 441 SLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVERP-PSPFSMAPQASLPPVPPR 499
SLL+Q + P+P + + +++L+ E P P P +AP + PP P
Sbjct: 4877 SLLKQES---PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPL 4933
Query: 500 LDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESR 559
++L + + P S L AS S P P RP G +SR
Sbjct: 4934 VELPTEPLAEPPVPSPLPLASSPESAR------------------PKPRARPPEEGEDSR 4975
Query: 560 PQR 562
P R
Sbjct: 4976 PPR 4978
Score = 30.8 bits (68), Expect = 6.0
Identities = 38/148 (25%), Positives = 55/148 (37%), Gaps = 17/148 (11%)
Query: 467 LFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGS 526
L M ++L ++ R P+ P P+ L PQ P + G + +G
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQ-EPGTQTSPLQGLLGCQPQLGGFPGPQT--GPLQELGAGP 4281
Query: 527 LHKDKP-LPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSR 585
+ P LP PP P P P P P +P + P R P PSS+
Sbjct: 4282 RPQGPPRLPAPPGALSTGPVLGPVHP-----------TPPPSSPQE-PKRPSQLPSPSSQ 4329
Query: 586 L-GDSWLPRPIPKVPVSAPSSSDPWTGR 612
L ++ LP P P + +P GR
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 56.2 bits (134), Expect = 1e-07
Identities = 94/411 (22%), Positives = 134/411 (32%), Gaps = 86/411 (20%)
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASAL------GTASKAASGSLHKD---K 531
PP P P PP PP LP + PS+ SA T ++ + S H K
Sbjct: 631 PPPPPPPPPPPPPPPPPP----LPSQ-SAPSAGSAAPMFVKYSTITRLQNASQHSGALFK 685
Query: 532 PLPVPPTLRD-------------LPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKL 578
P P PP ++ + PPPPP P + Q +P PC P +
Sbjct: 686 P-PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPS--LPQFSA 742
Query: 579 PPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRP--DVPR 636
PP P + + P P P +P LP Q P+P +P
Sbjct: 743 PPPPLKIHQVQHITQVAPPTPPPPP---------------PIPAPLPPQAPPKPLVTIPA 787
Query: 637 LGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEE 696
ST ++ ++ + P P K +P+ A+ I P PVP PP ++
Sbjct: 788 PTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPVPPP---TLPKQ 843
Query: 697 DTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLA 756
+ P PL P+ + + I SQ P L
Sbjct: 844 QSFCAKPPPSPLSPVPS-------------------VVKQIASQFPPPPTPPAMESQPLK 884
Query: 757 AAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEG 816
AN P+ PP + S I S F +
Sbjct: 885 PVPANVAPQ------------SPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 817 SQVPERPPKPFPRRINSERKAGS----CQQGSGPAASAATASPQLSSEIEN 863
S VP PP P P + K+GS + S P +PQ +S I++
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983
Score = 48.9 bits (115), Expect = 2e-05
Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 75/401 (18%)
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
P S +P PVPP Q C S L + P P PP +
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879
Query: 541 DLPPPP-----PPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPI 595
P P P P +V A+ + Q +P PS D PP P S L + P
Sbjct: 880 SQPLKPVPANVAPQSPPAVKAKPKWQPSSIP-----VPSPDFPPPPPESSL----VFPPP 930
Query: 596 PKVPVSAPSSSDPWTGRELTNRHSLP------FSLPSQMEPRPDVPRLGSTFSLDTSMSM 649
P PV AP P T ++ P S P +P P R
Sbjct: 931 PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR------------- 977
Query: 650 NSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLR 709
NSS +HP+ K S + + PP E G E + P + P +
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFT---------PPAE--SGSPSKETLPPPAAPPK 1026
Query: 710 PLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESE- 768
P + S Q C + ++AP ++ G G + + P +S+
Sbjct: 1027 PGKLNLSGVNLPGVLQ-QGC-------VSAKAPVLS-----GRGKDSVVEFPSPPSDSDF 1073
Query: 769 -NEDDGYDVPKPP--VPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPK 825
++P PP +PAV + T ++ +P V + PP
Sbjct: 1074 PPPPPETELPLPPIEIPAVFSGNTSPKVAVV-----------NPQPQQWSKMSVKKAPPP 1122
Query: 826 PFPRRINSERKAGSCQQGSGPAASAATASPQLSSEIENLMS 866
P+R +S R Q + AT PQ+ + ++ +S
Sbjct: 1123 TRPKRNDSTRLT---QAEISEQPTMATVVPQVPTSPKSSLS 1160
Score = 33.1 bits (74), Expect = 1.2
Identities = 63/283 (22%), Positives = 99/283 (34%), Gaps = 50/283 (17%)
Query: 516 LGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSR 575
L +SKA S+++ VPP L P P PY+ S P P P P P
Sbjct: 587 LEESSKARMESMNRPYTSLVPP----LSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPP- 641
Query: 576 DKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVP 635
PP P P P+P + S+ P + T S S +P P
Sbjct: 642 ---PPPP---------PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP 689
Query: 636 RLGSTFSLDTSMSMNSSPLVGPECDHP----------KIKPSSSANAIYSLAARPLPVPK 685
+ + S+ + + + +V P P ++KP+ A ++ +A P
Sbjct: 690 PVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP----- 744
Query: 686 LPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSIT 745
PP + + + T+ P+ P P+ +A T A + ++ AP +T
Sbjct: 745 -PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA----PPKPLVTIPAPTSTKTVAPVVT 799
Query: 746 ESSTFGEGNLAAAHANTGPEESENEDD----GYDVPKPPVPAV 784
+ AA T P + Y P PP P V
Sbjct: 800 Q---------AAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV 833
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 55.8 bits (133), Expect = 2e-07
Identities = 62/234 (26%), Positives = 85/234 (36%), Gaps = 36/234 (15%)
Query: 471 KELAGAKVERPPSPFSMAPQAS--------LPPVPPRLDLLPQRVCVPSSASALGTASKA 522
+++AG K + P + +P+ +PP PRL +++ A G A A
Sbjct: 115 RDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLG---------NTSEAHGAARTA 165
Query: 523 ASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVP 582
+ P P PPT PPP PP P S ++ P P T G+ P PPVP
Sbjct: 166 PP---RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV--VAPPVP 220
Query: 583 SSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFS 642
+ P P P P P + P LP P P +P G
Sbjct: 221 CAP-----PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP-G 274
Query: 643 LDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLP--------VPKLPP 688
L + + P P + P +S + SL A PLP P LPP
Sbjct: 275 LKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP 328
Score = 33.1 bits (74), Expect = 1.2
Identities = 34/130 (26%), Positives = 43/130 (33%), Gaps = 17/130 (13%)
Query: 493 LPPVPPRLDLLPQRVCVPSSASALGTASKAAS-----------GSLHKDKPLPVPP---- 537
LPP+PP L LLP A A A S LP PP
Sbjct: 257 LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGV 316
Query: 538 -TLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLG-DSWLPRPI 595
+ + PPP PP P + + LP P S+ L R G P
Sbjct: 317 NSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPP 376
Query: 596 PKVPVSAPSS 605
P P +P++
Sbjct: 377 PAPPARSPTT 386
Score = 32.3 bits (72), Expect = 2.1
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 532 PLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLP 566
PLP PP PPPPPP P V ++ RR P
Sbjct: 10 PLPPPPPPLGAPPPPPPSAP-PVSTDTSSLRRADP 43
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 55.5 bits (132), Expect = 2e-07
Identities = 72/243 (29%), Positives = 89/243 (36%), Gaps = 60/243 (24%)
Query: 481 PPSPFSMAPQASLPP--VPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLP-VPP 537
P P QA PP PPR D P P S+S L T S +A P P PP
Sbjct: 260 PSQPKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLATPSPSAP-------PSPSAPP 310
Query: 538 TLRDLPPP---PPPDRPYSVGAES---------RPQRRPLPCTPGDCPSRDKLPPVPSSR 585
+L+ LP P PP S+G+ + P PL P P LPP+ +
Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP- 369
Query: 586 LGDSWLPRPIPKVPVSAPSSSDPWTGREL-TNRHSLPFSLPSQMEPRPDVPRLGSTFSLD 644
P P P+S ++ P L + PFS P P P V
Sbjct: 370 ------PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP----PSPPV---------Q 410
Query: 645 TSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPS 704
S +SP V P P P SLAA PL VP PP + M+PS
Sbjct: 411 APFSPPASPPVSPSATPPSQAPP-------SLAAPPLQVPPSPPA--------SPPMSPS 455
Query: 705 SRP 707
+ P
Sbjct: 456 ATP 458
Score = 45.1 bits (105), Expect = 3e-04
Identities = 83/318 (26%), Positives = 104/318 (32%), Gaps = 48/318 (15%)
Query: 482 PSPFSMAPQASLPP-VPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
PSP ++P A+ PP PP L L P + P S A S A+ S L V
Sbjct: 343 PSP-PLSPLATPPPQAPPALALPPLQA--PPSPPASPPLSPLATPSPQAPNALAVHLLQA 399
Query: 541 DLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPV-------PSSRLGDSWLPR 593
PPP P + P P P P PP+ S + S P
Sbjct: 400 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459
Query: 594 PIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSP 653
P P++AP + + P P Q P P G S S+ SP
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATP---PLQALPSPPASFPGQA-PFSPSASLPMSP 515
Query: 654 LVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDT 713
L P P + LAA L VP PP P P DT
Sbjct: 516 LATPPPQAPPV-----------LAAPLLQVPPSPPA-------SPTLQAPRRPPTPGPDT 557
Query: 714 SQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLA--AAHANTGPEESENED 771
S S A+ PS + SST +LA ++ A + PEE D
Sbjct: 558 SVSGPRLTL----------ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 607
Query: 772 DGYD---VPKPPVPAVLA 786
G + PP A LA
Sbjct: 608 SGPEGGAAASPPPDAELA 625
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/158 (30%), Positives = 62/158 (39%), Gaps = 22/158 (13%)
Query: 481 PPSPFSMAPQASLPP-VPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTL 539
PP+ ++P A+ P PP L P +V P S A S +A+ PL PP
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQV--PPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472
Query: 540 RDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVP 599
PPP P A + P + LP P P + P PS+ L S L P P+ P
Sbjct: 473 LAKPPPQAPP------ALATPPLQALPSPPASFPG--QAPFSPSASLPMSPLATPPPQAP 524
Query: 600 --VSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVP 635
++AP P S P S Q RP P
Sbjct: 525 PVLAAPLLQVP---------PSPPASPTLQAPRRPPTP 553
Score = 37.4 bits (85), Expect = 0.064
Identities = 55/189 (29%), Positives = 68/189 (35%), Gaps = 53/189 (28%)
Query: 473 LAGAKVERPPSPFS---MAPQASLPP-------------------VPPRLDLLPQRVCVP 510
LA ++ PPSP + M+P A+ PP PP L P +
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS 494
Query: 511 SSASALGTASKAASGSLHKDKPLPVPP---------TLRDLPPPPP-------PDRPYSV 554
AS G A + S SL PL PP L +PP PP P RP +
Sbjct: 495 PPASFPGQAPFSPSASLPM-SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 555 GAESRPQ--RRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGR 612
G ++ R L PG PP P SR S L P ++ SSS T
Sbjct: 554 GPDTSVSGPRLTLALAPG--------PPPPPSRSPSSTLSGP----DLAGHSSSATSTPE 601
Query: 613 ELTNRHSLP 621
EL S P
Sbjct: 602 ELRGYDSGP 610
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 55.1 bits (131), Expect = 3e-07
Identities = 41/138 (29%), Positives = 53/138 (38%), Gaps = 15/138 (10%)
Query: 474 AGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPL 533
+G + PP+P PP PP LP VC+ S S G + +
Sbjct: 583 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAIS----------- 631
Query: 534 PVPPTLRDLPPPPPPDRPYSVG---AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSW 590
P PP D PPPP P VG S P +P P P ++PP P G +
Sbjct: 632 PPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP-PPPPLPGSARIPPPPPPLPGSAG 690
Query: 591 LPRPIPKVPVSAPSSSDP 608
+P P P +P A P
Sbjct: 691 IPPPPPPLPGEAGMPPPP 708
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 55.1 bits (131), Expect = 3e-07
Identities = 41/138 (29%), Positives = 53/138 (38%), Gaps = 15/138 (10%)
Query: 474 AGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPL 533
+G + PP+P PP PP LP VC+ S S G + +
Sbjct: 592 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAIS----------- 640
Query: 534 PVPPTLRDLPPPPPPDRPYSVG---AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSW 590
P PP D PPPP P VG S P +P P P ++PP P G +
Sbjct: 641 PPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP-PPPPLPGSARIPPPPPPLPGSAG 699
Query: 591 LPRPIPKVPVSAPSSSDP 608
+P P P +P A P
Sbjct: 700 IPPPPPPLPGEAGMPPPP 717
>gi|22027541 programmed cell death 7 [Homo sapiens]
Length = 485
Score = 53.5 bits (127), Expect = 9e-07
Identities = 42/114 (36%), Positives = 56/114 (49%), Gaps = 20/114 (17%)
Query: 482 PSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRD 541
P PF P AS P + P L L P+ ASA + +G+ + P+P PP
Sbjct: 45 PGPF---PGASAPFLQPPLALQPR-------ASAEASRGGGGAGAFY---PVPPPP---- 87
Query: 542 LPPPPPPDRPYSVGAESRPQRRPLPCTPGD--CPSRDKLPPVPSSRLGDSWLPR 593
LPPPPP RP+ G ++ + RP P PG P + PP P+ LGD+ L R
Sbjct: 88 LPPPPPQCRPFP-GTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQR 140
Score = 30.4 bits (67), Expect = 7.8
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 17/76 (22%)
Query: 533 LPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLP 592
+ +PP P PPP +P P P C P PS PP+P
Sbjct: 1 MALPPFFGQGRPGPPPPQP--------PPPAPFGCPPPPLPSPAFPPPLPQ--------- 43
Query: 593 RPIPKVPVSAPSSSDP 608
RP P SAP P
Sbjct: 44 RPGPFPGASAPFLQPP 59
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 53.1 bits (126), Expect = 1e-06
Identities = 64/224 (28%), Positives = 89/224 (39%), Gaps = 52/224 (23%)
Query: 473 LAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKP 532
L G + + P S +P ++ PP+PP T S+A DKP
Sbjct: 230 LGGGSIRQSPLS-SSSPFSNRPPLPP-------------------TPSRALD-----DKP 264
Query: 533 LPVPPTLRD--------LPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSS 584
P PP + + +PPPPP + V + RP P PSR PP+P S
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
Query: 585 RLGDSWLPRPIPKVPVSAPSSSDPW--TGRE------LTNRHSLPFSLP----SQMEPRP 632
G+ PR +P+ +S SS+ P GR + R P P + P P
Sbjct: 325 SSGNDETPR-LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383
Query: 633 DVPRLGSTF-SLDTSMSMNS-----SPLVGPECDHPKIKPSSSA 670
V R GST +L + + S SP GP P +PS+ A
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGA 427
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/136 (33%), Positives = 54/136 (39%), Gaps = 25/136 (18%)
Query: 481 PPSPFSMAPQASLPPVPP------RLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLP 534
PP P P PP+PP LPQR + S+S S SG PLP
Sbjct: 310 PPPPSRPGP----PPLPPSSSGNDETPRLPQRN-LSLSSSTPPLPSPGRSG------PLP 358
Query: 535 VPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSR--DKLPPVPSSRLGDSWLP 592
PP+ R PPPP D P S P P P + SR P +PS DS
Sbjct: 359 PPPSER--PPPPVRDPP----GRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
Query: 593 RPIPKVPVSAPSSSDP 608
P P +P PS+ P
Sbjct: 413 GPRPPLPPDRPSAGAP 428
Score = 34.3 bits (77), Expect = 0.54
Identities = 41/138 (29%), Positives = 48/138 (34%), Gaps = 18/138 (13%)
Query: 479 ERPPSPFSMAPQAS--LPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVP 536
ERPP P P S LPP PP +P++ L + S S PLP
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ-LPSRSGVDSPRSGPRPPLPPD 421
Query: 537 PTLRDLPPPPPP---------DRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPS---- 583
PPPPPP D P ESR P+ P P PS
Sbjct: 422 RPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLAR 481
Query: 584 --SRLGDSWLPRPIPKVP 599
SR G + R P +P
Sbjct: 482 NESRSGSNRRERGAPPLP 499
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 53.1 bits (126), Expect = 1e-06
Identities = 64/224 (28%), Positives = 89/224 (39%), Gaps = 52/224 (23%)
Query: 473 LAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKP 532
L G + + P S +P ++ PP+PP T S+A DKP
Sbjct: 230 LGGGSIRQSPLS-SSSPFSNRPPLPP-------------------TPSRALD-----DKP 264
Query: 533 LPVPPTLRD--------LPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSS 584
P PP + + +PPPPP + V + RP P PSR PP+P S
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
Query: 585 RLGDSWLPRPIPKVPVSAPSSSDPW--TGRE------LTNRHSLPFSLP----SQMEPRP 632
G+ PR +P+ +S SS+ P GR + R P P + P P
Sbjct: 325 SSGNDETPR-LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383
Query: 633 DVPRLGSTF-SLDTSMSMNS-----SPLVGPECDHPKIKPSSSA 670
V R GST +L + + S SP GP P +PS+ A
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGA 427
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/136 (33%), Positives = 54/136 (39%), Gaps = 25/136 (18%)
Query: 481 PPSPFSMAPQASLPPVPP------RLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLP 534
PP P P PP+PP LPQR + S+S S SG PLP
Sbjct: 310 PPPPSRPGP----PPLPPSSSGNDETPRLPQRN-LSLSSSTPPLPSPGRSG------PLP 358
Query: 535 VPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSR--DKLPPVPSSRLGDSWLP 592
PP+ R PPPP D P S P P P + SR P +PS DS
Sbjct: 359 PPPSER--PPPPVRDPP----GRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
Query: 593 RPIPKVPVSAPSSSDP 608
P P +P PS+ P
Sbjct: 413 GPRPPLPPDRPSAGAP 428
Score = 34.3 bits (77), Expect = 0.54
Identities = 41/138 (29%), Positives = 48/138 (34%), Gaps = 18/138 (13%)
Query: 479 ERPPSPFSMAPQAS--LPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVP 536
ERPP P P S LPP PP +P++ L + S S PLP
Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ-LPSRSGVDSPRSGPRPPLPPD 421
Query: 537 PTLRDLPPPPPP---------DRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPS---- 583
PPPPPP D P ESR P+ P P PS
Sbjct: 422 RPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLAR 481
Query: 584 --SRLGDSWLPRPIPKVP 599
SR G + R P +P
Sbjct: 482 NESRSGSNRRERGAPPLP 499
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 52.8 bits (125), Expect = 1e-06
Identities = 71/279 (25%), Positives = 102/279 (36%), Gaps = 32/279 (11%)
Query: 432 DPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQA 491
+ F+ G + L GA S +++ D +T + E + ++ PP P + A
Sbjct: 1164 EDFEQDGEEAALAPGAPAVDSLGMEEEVDI---ETEAVAPEERPSMLDEPPLPVGVEEPA 1220
Query: 492 SL--PPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPL---PVPPTLRDLP--- 543
PP P L + P + A S + L P PP + LP
Sbjct: 1221 DSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP 1280
Query: 544 --PPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPS--SRLGDSWLPRPIPKVP 599
PPP P RP S E P P + + D P P L S +P P
Sbjct: 1281 PLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATP 1340
Query: 600 VSAPSSSDPWTGRELTNRH--SLPFSLPSQMEPRPD-----VPRL-GSTFSLDTSMSMNS 651
P S +G L++ PFS P+ P P +PR G FS + S S
Sbjct: 1341 GGEPPLSGGSSGLSLSSPQVPGSPFSYPA---PSPSLSSGGLPRTPGRDFSFTPTFSEPS 1397
Query: 652 SPLVGPECDHP------KIKPSSSANAIYSLAARPLPVP 684
PL+ P C P + P +S + + PLP+P
Sbjct: 1398 GPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLP 1436
Score = 45.1 bits (105), Expect = 3e-04
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 13/87 (14%)
Query: 517 GTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRD 576
G A+ AA L PLP PP LPPPPPP P P PLP P
Sbjct: 665 GAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPP----QPGFPMPPPLPPPP------- 713
Query: 577 KLPPVPSSRLGDSWLPRPIPKVPVSAP 603
PP P + + P P+P P P
Sbjct: 714 --PPPPPAHPAVTVPPPPLPAPPGVPP 738
Score = 38.1 bits (87), Expect = 0.037
Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 24/100 (24%)
Query: 483 SPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDL 542
+P +AP LPP PP LP P P+PP L
Sbjct: 671 APSVLAPTLPLPP-PPGFPPLPPPPPPPPPQPGF-----------------PMPPPL--- 709
Query: 543 PPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVP 582
PPPPPP P P PLP PG P LPP+P
Sbjct: 710 PPPPPPPPPAHPAVTVPPP--PLPAPPG-VPPPPILPPLP 746
Score = 33.9 bits (76), Expect = 0.70
Identities = 38/142 (26%), Positives = 47/142 (33%), Gaps = 38/142 (26%)
Query: 474 AGAKVERPPSPFSMAPQASLPPV-----------PPRLDLLPQRVCVPSSASALGTASKA 522
A A+ P P AP AS PP PP + L + P + +ALG
Sbjct: 1449 AQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLL 1508
Query: 523 ASG--------SLHKDK-----------PLPVPPTLRDLPPPPPPDRPYSVGAESRPQRR 563
G S H + P P PP PPPPPP P +
Sbjct: 1509 LPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPP-------PPVEPTKL 1561
Query: 564 PLPCTPGDCPSRDKLPPVPSSR 585
P PS + +PP P R
Sbjct: 1562 PFKELDNQWPS-EAIPPGPRGR 1582
Score = 30.4 bits (67), Expect = 7.8
Identities = 51/215 (23%), Positives = 68/215 (31%), Gaps = 21/215 (9%)
Query: 483 SPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLP-VPPTLRD 541
SP+ P A PP P P++ +A G PLP P ++
Sbjct: 398 SPYQ-TPVAHFPPPPEE----------PTATAAFGARDSGEFRRAPAPPPLPPAEPLAKE 446
Query: 542 LP-----PPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLG--DSWLPRP 594
P PPPP +G P PC P+ + P P DS +
Sbjct: 447 KPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEML 506
Query: 595 IPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEP-RPDVPRLGSTFSLDTSMSMNSSP 653
+ + +P + EL S S SQ+ P P F T S S
Sbjct: 507 LKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSS 566
Query: 654 LVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPP 688
G E P P S + L P P P+ P
Sbjct: 567 -TGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGP 600
>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
Length = 616
Score = 52.0 bits (123), Expect = 3e-06
Identities = 52/190 (27%), Positives = 72/190 (37%), Gaps = 20/190 (10%)
Query: 373 EMGSTFQLCKICAEND-KDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVV 431
E+ + +C IC E K PC H+ TSCL SW + + Q CP CR ++
Sbjct: 283 ELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQ-QTCPTCRMDVLRASLPAQ 341
Query: 432 DPFDPRGSGSLLRQGAEGAP--------SPNYDDDDDERADDTLFMMKELAGAKVERPPS 483
P P + QG AP PN+ +F + G PP
Sbjct: 342 SPPPPEPAD----QGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
Query: 484 PFS---MAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKP---LPVPP 537
P S +AP ++ + S+ +A TAS SGS + P P PP
Sbjct: 398 PSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPP 457
Query: 538 TLRDLPPPPP 547
+P PPP
Sbjct: 458 PWMGMPLPPP 467
Score = 33.1 bits (74), Expect = 1.2
Identities = 63/263 (23%), Positives = 87/263 (33%), Gaps = 36/263 (13%)
Query: 534 PVPPTLRDLPPPPPP-DRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLP 592
P PP D PPP P P + PQ P PG P + P P
Sbjct: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP---------- 392
Query: 593 RPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSS 652
P+P P S + + P T L S P + +T S S+
Sbjct: 393 -PVPPPPSSGEAVAPPSTSAAL----SRPSGAATTTAAGTSATAASATAS---GPGSGSA 444
Query: 653 PLVGPECDHPKIKPSSSANAIYSLAARPLPVPK-----LPPGE--QCEGEEDTEYMTPSS 705
P GP P P A P+PVP L P E EG E +++
Sbjct: 445 PEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHE-RQHLEARL 503
Query: 706 RPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGP- 764
+ LR + T + +Q + T A A S+ + +AAA + + P
Sbjct: 504 QSLRNIHTLLDAAMLQINQYL---TVLASLGPPRPATSVNSTEETATTVVAAASSTSIPS 560
Query: 765 EESENEDDGYDVP-----KPPVP 782
E+ G P +PP P
Sbjct: 561 SEATTPTPGASPPAPEMERPPAP 583
>gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase
4 [Homo sapiens]
Length = 1039
Score = 52.0 bits (123), Expect = 3e-06
Identities = 71/257 (27%), Positives = 100/257 (38%), Gaps = 45/257 (17%)
Query: 451 PSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMA-PQASL-PPVPPRLDLLPQRVC 508
P DD+D+ D+L + + P+P + A P A+L PP PPR P+
Sbjct: 431 PDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPR----PRDGG 486
Query: 509 VPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPP-----PPPDRPYSVGAESRPQRR 563
P + AL A++AA P+P L PPP PP + Y RP +R
Sbjct: 487 TPRHSRALSWAARAAR---------PLPLFLGRAPPPRPAVEQPPPKVYVTRV--RPGQR 535
Query: 564 PLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFS 623
P P R PP P L PRP+P+V + AP GR
Sbjct: 536 ASPRAPAP---RAPWPPFPGVFLH----PRPLPRVQLRAPPRPPRPHGRRTGG------- 581
Query: 624 LPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYS-LAARPLP 682
P +PRP + + + +GP SS A + S L+ +
Sbjct: 582 -PQATQPRPPARAQATQGGRE-----GQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVS 635
Query: 683 VPKLP--PGEQCEGEED 697
P+LP E+ EGE+D
Sbjct: 636 GPQLPGEGEEEEEGEDD 652
>gi|5902054 ring finger protein 5 [Homo sapiens]
Length = 180
Score = 51.2 bits (121), Expect = 4e-06
Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 9/85 (10%)
Query: 375 GSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQES--EGQGCPFCRCEIKGTEPIVV- 431
G+TF+ C IC E ++ + CGHL C CL W E+ E Q CP C+ I + + +
Sbjct: 22 GATFE-CNICLETAREAVVSVCGHLYCWPCLHQWLETRPERQECPVCKAGISREKVVPLY 80
Query: 432 -----DPFDPRGSGSLLRQGAEGAP 451
P DPR QG AP
Sbjct: 81 GRGSQKPQDPRLKTPPRPQGQRPAP 105
>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
Length = 617
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/191 (28%), Positives = 73/191 (38%), Gaps = 21/191 (10%)
Query: 373 EMGSTFQLCKICAEND-KDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVV 431
E+ + +C IC E K PC H+ TSCL SW + + Q CP CR ++
Sbjct: 283 ELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQ-QTCPTCRMDVLRASLPAQ 341
Query: 432 DPFDPRGSGSLLRQGAEGAP--------SPNYDDDDDERADDTLFMMKELAGAKVERPPS 483
P P + QG AP PN+ +F + G PP
Sbjct: 342 SPPPPEPAD----QGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPP 397
Query: 484 PFS---MAPQASLPPVPPRLDLLPQRVCVPSSASAL-GTASKAASGSLHKDKP---LPVP 536
P S +AP ++ R +SA+A TAS SGS + P P P
Sbjct: 398 PSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFP 457
Query: 537 PTLRDLPPPPP 547
P +P PPP
Sbjct: 458 PPWMGMPLPPP 468
Score = 32.7 bits (73), Expect = 1.6
Identities = 62/263 (23%), Positives = 87/263 (33%), Gaps = 35/263 (13%)
Query: 534 PVPPTLRDLPPPPPP-DRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLP 592
P PP D PPP P P + PQ P PG P + P P
Sbjct: 343 PPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFP---------- 392
Query: 593 RPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSS 652
P+P P S + + P T +R P + +T S S+
Sbjct: 393 -PVPPPPSSGEAVAPPSTSAAALSR---PSGAATTTAAGTSATAASATAS---GPGSGSA 445
Query: 653 PLVGPECDHPKIKPSSSANAIYSLAARPLPVPK-----LPPGE--QCEGEEDTEYMTPSS 705
P GP P P A P+PVP L P E EG E +++
Sbjct: 446 PEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHE-RQHLEARL 504
Query: 706 RPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGP- 764
+ LR + T + +Q + T A A S+ + +AAA + + P
Sbjct: 505 QSLRNIHTLLDAAMLQINQYL---TVLASLGPPRPATSVNSTEETATTVVAAASSTSIPS 561
Query: 765 EESENEDDGYDVP-----KPPVP 782
E+ G P +PP P
Sbjct: 562 SEATTPTPGASPPAPEMERPPAP 584
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/101 (35%), Positives = 45/101 (44%), Gaps = 19/101 (18%)
Query: 521 KAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVG-----AESR------PQRRPLPCTP 569
+A L + P P PP+ PPPPPP P++ G A R P R P P
Sbjct: 266 EAVKNELRRQAPPPPPPSRGGPPPPPPP--PHNSGPPPPPARGRGAPPPPPSRAPTAAPP 323
Query: 570 GDCPSRDK--LPPVPSSRLGDSWLPRPIPKVPVSAPSSSDP 608
PSR +PP P +R+ P P P +P SAPS P
Sbjct: 324 PPPPSRPSVAVPPPPPNRM----YPPPPPALPSSAPSGPPP 360
Score = 44.7 bits (104), Expect = 4e-04
Identities = 47/150 (31%), Positives = 51/150 (34%), Gaps = 31/150 (20%)
Query: 479 ERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPT 538
+ PP P P PP PP P P A G + P PP
Sbjct: 275 QAPPPP---PPSRGGPPPPPP----PPHNSGPPPPPARGRGA-------------PPPPP 314
Query: 539 LRD---LPPPPPPDRPYSVGAESRPQRR----PLPCTPGDCPSRDKLPPVPSSRLGDSWL 591
R PPPPPP RP SV P R P P P PS PP P S LG +
Sbjct: 315 SRAPTAAPPPPPPSRP-SVAVPPPPPNRMYPPPPPALPSSAPSGP--PPPPPSVLGVGPV 371
Query: 592 PRPIPKVPVSAPSSSDPWTGRELTNRHSLP 621
P P P P P G H +P
Sbjct: 372 APPPPPPPPPPPGPPPP-PGLPSDGDHQVP 400
Score = 39.3 bits (90), Expect = 0.017
Identities = 24/76 (31%), Positives = 30/76 (39%)
Query: 476 AKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPV 535
A PP P P ++PP PP P +PSSA + + + P P
Sbjct: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPP 376
Query: 536 PPTLRDLPPPPPPDRP 551
PP PPPPP P
Sbjct: 377 PPPPPPPGPPPPPGLP 392
>gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]
Length = 1133
Score = 50.4 bits (119), Expect = 7e-06
Identities = 72/298 (24%), Positives = 103/298 (34%), Gaps = 52/298 (17%)
Query: 481 PPSP---FSMAPQASLPPVPPRLD----LLPQRVCVPSSASALGTASKAASGSLHKDKPL 533
PPS P+ L P+PP D P+ + P SAL +A +A +L
Sbjct: 313 PPSADDNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSALPSAPPSADDNLKTRAEC 372
Query: 534 ---PVPPTLRD------------LPPPPPPDRPYSVGAESRPQRRPLPCTPGD---CPSR 575
P+PP+ D LPP PP ++ + R PLP + D PS
Sbjct: 373 LLHPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSE 432
Query: 576 DKLPPVPSSR--LGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPD 633
+L P+P S D + P ++ P S+D +L Q+ P P
Sbjct: 433 RQLTPLPPSAPPSADDNIKTPAERLRGPLPPSAD----------DNLKTPSERQLTPLPP 482
Query: 634 VPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVP------KLP 687
+ ++ T PL D+ K A+ A + P LP
Sbjct: 483 SAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTALPPSADDNIKTPAERLRGPLP 542
Query: 688 PGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSIT 745
P D TPS R L PL S A D I + + I PS++
Sbjct: 543 P------SADDNLKTPSERQLTPLPPSAPPSA---DDNIKTPAFHPQRMISRHLPSVS 591
Score = 34.3 bits (77), Expect = 0.54
Identities = 42/163 (25%), Positives = 60/163 (36%), Gaps = 17/163 (10%)
Query: 534 PVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGD---CPSRDKLPPVPSSR--LGD 588
P L LPP PP ++ + R PLP + D PS +L P+P S D
Sbjct: 885 PSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSAD 944
Query: 589 SWLPRPIPK----VPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVP--RLGSTFS 642
+ P + +P SA + + R+LT LP S P + P RL
Sbjct: 945 DNIKTPAERLRGPLPPSADDNLKTPSERQLT---PLPPSAPPSADDNIKTPAERLRGPLP 1001
Query: 643 LDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPK 685
++ + PL E + K + A P P PK
Sbjct: 1002 PSADDNLKTPPLATQEAEAEKPRKPKRQRA---AEMEPPPEPK 1041
Score = 32.3 bits (72), Expect = 2.1
Identities = 61/252 (24%), Positives = 80/252 (31%), Gaps = 48/252 (19%)
Query: 510 PSSASALGTASKAASGSLHKDKPLPVPPTL-------RDLPPPPPPDRPYSVGAESRPQR 562
PS+ AL + A+ LP P L R PPPP + +S+ S +
Sbjct: 205 PSARKALCNWVRMAAAEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSITDNSLSLK 264
Query: 563 RPLPC----TPGDCPSRDKLPP----VPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGREL 614
P C P K PP P D L P V P S+D
Sbjct: 265 TPPECLLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPPECVLTPLPPSAD------- 317
Query: 615 TNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECD-----------HPK 663
N + P L + + P D L T + ++ P P D HP
Sbjct: 318 DNLKTPPECLLTPLPPSADDNLKTPPECLLTPLPPSALPSAPPSADDNLKTRAECLLHP- 376
Query: 664 IKPSSSANAIYSLAARPLPVPK----------LPPGEQCEG----EEDTEYMTPSSRPLR 709
+ PS+ N + P+P P E+ G D TPS R L
Sbjct: 377 LPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLT 436
Query: 710 PLDTSQSSRACD 721
PL S A D
Sbjct: 437 PLPPSAPPSADD 448
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 50.4 bits (119), Expect = 7e-06
Identities = 49/206 (23%), Positives = 73/206 (35%), Gaps = 26/206 (12%)
Query: 453 PNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSS 512
P++ D+++ + + ++ A P + S P PP L VP
Sbjct: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPP----LAPAAAVPGP 1433
Query: 513 ASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDC 572
G S ++G+ P PP L + PPP PP P P P P P
Sbjct: 1434 PPLPGLPSANSNGT-------PEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP 1486
Query: 573 PSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQ--MEP 630
P + P PSS P P P +P S P P + P + P + P
Sbjct: 1487 P---LVAPTPSSPPPPPLPPPPPPAMP-SPPPPPPP---------AAAPLAAPPEEPAAP 1533
Query: 631 RPDVPRLGSTFSLDTSMSMNSSPLVG 656
P+ P L T L + ++ + G
Sbjct: 1534 SPEDPELPDTRPLHLAKKQETAAVCG 1559
Score = 43.1 bits (100), Expect = 0.001
Identities = 77/323 (23%), Positives = 110/323 (34%), Gaps = 43/323 (13%)
Query: 539 LRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKV 598
L+ PPPPPP ++P L G LPP P LP +
Sbjct: 760 LQKSPPPPPP-----TAQSTQPTPHGLLLEAGGPDLPLVLPPPP-----PQLLPSVLSHA 809
Query: 599 PVSAPSSSDPWTG-RELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGP 657
P +PS+S E R P P P P +P L + S L P
Sbjct: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP-------LQLEAHLRSHGL-EP 861
Query: 658 ECDHPKIKPSSSAN---AIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTS 714
P+++P S + A+ L P+P PG+ G ++E P+ P +
Sbjct: 862 AAPSPRLRPEESLDPPGAMQELLGALEPLPP-APGDTGVGPPNSEGKDPAGAYRSP--SP 918
Query: 715 QSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGY 774
Q ++A C +++ + ++ T FG G A + GP E E +
Sbjct: 919 QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFG-GGAADDYGKAGPPEDEGDPKAG 977
Query: 775 DVPKPPVPAV--LARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRIN 832
P P PA S A L LD P +PP+ P +N
Sbjct: 978 AGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLD-------------PNKPPE-LPSTVN 1023
Query: 833 SERKAGSCQQGSGPAASAATASP 855
+E G Q G AA P
Sbjct: 1024 AE-PLGLIQSGPHQAAPPPPPPP 1045
Score = 30.8 bits (68), Expect = 6.0
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 10/79 (12%)
Query: 493 LPPVPPRLDLLPQRVCVPSSASALGTASKAASG-SLHKDKPLPVPPTLRDLPPPPPPDRP 551
LPP PP+L +PS S + S +AS +H +P + PPPPPP P
Sbjct: 794 LPPPPPQL--------LPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPP 845
Query: 552 YSVGAESRPQRRPL-PCTP 569
+ E+ + L P P
Sbjct: 846 MPLQLEAHLRSHGLEPAAP 864
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 49.3 bits (116), Expect = 2e-05
Identities = 69/237 (29%), Positives = 93/237 (39%), Gaps = 47/237 (19%)
Query: 476 AKVERPPS-PFSMAPQASLPPVPPRLDLLP----QRVCVPS----SASALGTASKAASG- 525
A+V RP P P PP P L P + +P+ A ASK AS
Sbjct: 416 ARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASAR 475
Query: 526 -SLHK--------DKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRD 576
S HK P P P + R PP P S S P+ P TPG P+
Sbjct: 476 TSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTS--GTSTPRTAPAVPTPGSAPTGS 533
Query: 577 KLP--PVPSSRLGDSWLPR-PIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPD 633
K P S + G PR P+P P A + P + +LT R PS +P+P
Sbjct: 534 KKPIGSEASKKAGPKSSPRKPVPLRPGKA-ARDVPLS--DLTTR-------PSPRQPQPS 583
Query: 634 VPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLA-ARPLPVPKLPPG 689
+ L + ++SSP +P+SS +I+ LA + P P+ PPG
Sbjct: 584 -QQTTPALVLAPAQFLSSSP-----------RPTSSGYSIFHLAGSTPFPLLMGPPG 628
Score = 38.5 bits (88), Expect = 0.029
Identities = 58/240 (24%), Positives = 90/240 (37%), Gaps = 51/240 (21%)
Query: 492 SLPPVP--PRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPD 549
SLP P P ++P + P+ +A + +K+A + + VPPT R +P
Sbjct: 367 SLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQ-----VPPTSRPVP------ 415
Query: 550 RPYSVGAESRPQRRPLPCTPG----DCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPS- 604
SRP +P+ PG PS LPP SS +PIP + +
Sbjct: 416 -----ARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSS------KKPIPTLARTEAKI 464
Query: 605 ---SSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDH 661
+S P + R T++ +L S P P GST S +M
Sbjct: 465 TSHASKPASARTSTHKPPPFTALSSSPAPTP-----GSTRSTRPPATM------------ 507
Query: 662 PKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACD 721
+ P+S + + A P P ++ G E ++ P S P +P+ A D
Sbjct: 508 --VPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARD 565
Score = 36.6 bits (83), Expect = 0.11
Identities = 53/233 (22%), Positives = 84/233 (36%), Gaps = 28/233 (12%)
Query: 482 PSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRD 541
PS F+ + + VPP +P RV S+ A + ++ +P PP
Sbjct: 393 PSSFTKSALPTQKQVPPTSRPVPARV------------SRPAEKPIQRNPGMPRPPPPST 440
Query: 542 LPPPPPPD---RPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKV 598
P PP +P A + + P + PP P + L S P
Sbjct: 441 RPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPP-PFTALSSSPAP-----T 494
Query: 599 PVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPE 658
P S S+ P T T+ S P + P+ P P GS + + S + P P
Sbjct: 495 PGSTRSTRPPATMVPPTSGTSTPRTAPA--VPTPGSAPTGSKKPIGSEASKKAGPKSSPR 552
Query: 659 CDHPKIKPSSSANAIYSLAARPLPVPKLP-PGEQCEGE---EDTEYMTPSSRP 707
P ++P +A + P P+ P P +Q ++++ S RP
Sbjct: 553 KPVP-LRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRP 604
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 49.3 bits (116), Expect = 2e-05
Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 6/52 (11%)
Query: 3 GNVKKSSGAGGGSGSGGSGSGGLI--GLMK----DAFQPHHHHHHHLSPHPP 48
G + G GGG G G G+ L+ GL++ + + HHHHHHH PHPP
Sbjct: 232 GMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPP 283
Score = 31.6 bits (70), Expect = 3.5
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 2 AGNVKKS--SGAGGGSGSGGSGSGGLIGLMKDAFQP 35
AG++ S +GAGGG G GG G GG G QP
Sbjct: 18 AGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQP 53
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 8/147 (5%)
Query: 489 PQASLPPVPPRLDLLPQRVCVPSSASALGTASKAA--SGSLHKDKPLPVPPTLR-DLPPP 545
P A +P VP ++ ++ ++V VP T + +K +PVPP + + PPP
Sbjct: 10465 PPAKVPEVPKKI-VVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPP 10523
Query: 546 PPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSS 605
P+ P V E + P P P P+ K+P VP + + + +P IP P S P
Sbjct: 10524 KVPEAPKEVVPEKKVPVPP-PKKPEVPPT--KVPEVPKAAVPEKKVPEAIPPKPESPPPE 10580
Query: 606 SDPWTGRELTNRHSLPFSLPSQMEPRP 632
P +E+ +P + P + E P
Sbjct: 10581 V-PEAPKEVVPEKKVPAAPPKKPEVTP 10606
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 9/103 (8%)
Query: 531 KPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRR-PLPCTPGDCPSRDKLPPVPSSRLGDS 589
KP+PVP ++ PP P+ P +P+ + P+ + P K+P VP + +
Sbjct: 9963 KPVPVPKK-KEAPPAKVPEVP------KKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEE 10015
Query: 590 WLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRP 632
+P P+PK V AP + P ++ +P P ++E P
Sbjct: 10016 KVPVPVPK-KVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPP 10057
Score = 39.3 bits (90), Expect = 0.017
Identities = 61/263 (23%), Positives = 92/263 (34%), Gaps = 43/263 (16%)
Query: 477 KVERPPSPFSMAPQASLP----PVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKP 532
K E PP AP+ +P PVPP P++ VP + + KAA K P
Sbjct: 10517 KPEAPPPKVPEAPKEVVPEKKVPVPP-----PKKPEVPPTK--VPEVPKAAVPE--KKVP 10567
Query: 533 LPVPPTLRDLPPPPPPDRPYSVGAESR----PQRRP-------------------LPCTP 569
+PP + PPP P+ P V E + P ++P +P P
Sbjct: 10568 EAIPPK-PESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626
Query: 570 GDCPS--RDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQ 627
P K+P VP + + +P IP P S P + + E P +
Sbjct: 10627 PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPP--PEVFEEPEEVALEEPPAEVVE- 10683
Query: 628 MEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLP 687
EP P P + + +V + + P +K + PL VPK P
Sbjct: 10684 -EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKP 10742
Query: 688 PGEQCEGEEDTEYMTPSSRPLRP 710
+ E + + P + P
Sbjct: 10743 EAPPAKVPEVPKEVVPEKKVAVP 10765
Score = 38.1 bits (87), Expect = 0.037
Identities = 59/328 (17%), Positives = 107/328 (32%), Gaps = 39/328 (11%)
Query: 532 PLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWL 591
P+P+P + P P P+ P E +++P+P + + K+P VP + + +
Sbjct: 9302 PVPIPKKVEP-PAPKVPEVPKKPVPE---EKKPVPVPKKEPAAPPKVPEVPKKPVPEEKI 9357
Query: 592 PRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNS 651
P P+ K AP + P + + + + P P VP + +
Sbjct: 9358 PVPVAKKK-EAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKK-----KVPEER 9411
Query: 652 SPLVGPECD---HPKIKPSSSANAIYSLAARPLPVPKLPPGEQCE-------------GE 695
P+ E + PK+ A P+PV K P + E E
Sbjct: 9412 KPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAE 9471
Query: 696 EDTEYMTPSSRPLRPLDTSQSSRACDCDQQ--IDSCTYEAMYNIQSQAPSITESSTFGEG 753
E + P + + S +++ + Y + + +TE E
Sbjct: 9472 EKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEP 9531
Query: 754 ---------NLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLS 804
++ + P E + V KP +PA + + + A
Sbjct: 9532 EEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEK 9591
Query: 805 LDGDPTTNVTE--GSQVPERPPKPFPRR 830
P + +VPE P KP P +
Sbjct: 9592 KVPAPVPKKEKVPPPKVPEEPKKPVPEK 9619
Score = 38.1 bits (87), Expect = 0.037
Identities = 34/161 (21%), Positives = 66/161 (40%), Gaps = 14/161 (8%)
Query: 479 ERPPSPFSMAPQASLPPVP--PRLDLLPQRVCVPSSASALGTASKAAS---GSLHKDKPL 533
E+ P P A+ P VP P+ + +++ VP + +K G + ++K +
Sbjct: 9327 EKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEK-I 9385
Query: 534 PVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPR 593
+ + PPP P+ P E +R+P+P + P K+P +P + + +
Sbjct: 9386 TIVTQREESPPPAVPEIPKKKVPE---ERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAV 9442
Query: 594 PIPKVPVSAP-----SSSDPWTGRELTNRHSLPFSLPSQME 629
P+P + P S + L F++P ++E
Sbjct: 9443 PVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVE 9483
Score = 35.8 bits (81), Expect = 0.19
Identities = 53/244 (21%), Positives = 87/244 (35%), Gaps = 51/244 (20%)
Query: 447 AEGAPSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQR 506
AE P Y++ ++ ++ + A E P P + + +PP P + P++
Sbjct: 10796 AESPPPEVYEEPEEIAPEEEI--------APEEEKPVPVAEEEEPEVPP--PAVPEEPKK 10845
Query: 507 VCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLP 566
+ +P + +A + + + P L+ PPPPPP P E Q + +P
Sbjct: 10846 I-IPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIP 10904
Query: 567 CTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPS 626
+ K+P P +P + P+ P G E R LP P
Sbjct: 10905 --------KKKVPEKPQ-------VPEKVELTPLKVP-------GGEKKVRKLLPERKP- 10941
Query: 627 QMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKL 686
EP+ +V + S PE + PK++P A P P P
Sbjct: 10942 --EPKEEV-------------VLKSVLRKRPEEEEPKVEPKKLEKV--KKPAVPEPPPPK 10984
Query: 687 PPGE 690
P E
Sbjct: 10985 PVEE 10988
Score = 35.0 bits (79), Expect = 0.32
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 12/151 (7%)
Query: 543 PPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSA 602
PPP P+ P E + P+P P K+P VP + + P P+PK +A
Sbjct: 9284 PPPKVPELPEKPAPE---EVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAA 9340
Query: 603 PSSSDPWTGRELTNRHSLPFSLPSQME-PRPDVPRLGSTFSLDTSMSM-----NSSPLVG 656
P P ++ +P + + E P VP + + +++ S P
Sbjct: 9341 PPKV-PEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAV 9399
Query: 657 PECDHPKIKPSSSANAIYSLAARPLPVPKLP 687
PE PK K + P PK+P
Sbjct: 9400 PEI--PKKKVPEERKPVPRKEEEVPPPPKVP 9428
Score = 34.3 bits (77), Expect = 0.54
Identities = 40/160 (25%), Positives = 66/160 (41%), Gaps = 23/160 (14%)
Query: 479 ERPPSPFSM---APQASLPPVPPRLD-----LLPQRVCVPSSASALGTASKAASGSLHKD 530
E+ P P AP A +P VP + + L+P++ P + + + ++
Sbjct: 9961 EKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAK-----VPEVPKKPVPEE 10015
Query: 531 K-PLPVPPTLRDLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDS 589
K P+PVP + + PP P+ P E + P+P K+P VP + +
Sbjct: 10016 KVPVPVPKKV-EAPPAKVPEVPKKPVPEKKV---PVPAPKKVEAPPAKVPEVPKKLIPEE 10071
Query: 590 WLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQME 629
P P+PK V AP P + +P +LP + E
Sbjct: 10072 KKPTPVPK-KVEAPPPKVPKKREPV----PVPVALPQEEE 10106
Score = 33.1 bits (74), Expect = 1.2
Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 16/142 (11%)
Query: 474 AGAKVERPPSPFSMAPQASLP------PVPPRLDLLPQRVCVPSSASALGTASKAASGSL 527
A KVE PP+ P+ +P PVP +++ P +V + A L
Sbjct: 10049 APKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVL 10108
Query: 528 HKDKPLPVPPTLRDLPPPPPPDRPYSVGAES-RPQRRPLPCTPGDCPSRDKLPP-----V 581
+++ +P L + P + E P+ +P + P ++ P V
Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168
Query: 582 PSSRLGDSWLPRPIPKVPVSAP 603
P + LP PKVPV AP
Sbjct: 10169 PEEEV----LPEVKPKVPVPAP 10186
Score = 31.6 bits (70), Expect = 3.5
Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 17/149 (11%)
Query: 460 DERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTA 519
+++A + EL KV P P + P+ +P V P+ P VP +
Sbjct: 10703 EKKAPAVVAKKPELPPVKV--PEVPKEVVPEKKVPLVVPKKPEAPPAK-VPEVPKEVVPE 10759
Query: 520 SKAASGSLHKDKPLPVP-----PTLRDLPPPPPPDRPYSVGAESRP---QRRPLPCTPGD 571
K A + P VP P L + P P P+R AES P P P +
Sbjct: 10760 KKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPER-----AESPPPEVYEEPEEIAPEE 10814
Query: 572 CPSRDKLPPVPSSRLGDSWLPRP-IPKVP 599
+ ++ PVP + + +P P +P+ P
Sbjct: 10815 EIAPEEEKPVPVAEEEEPEVPPPAVPEEP 10843
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/193 (23%), Positives = 67/193 (34%), Gaps = 26/193 (13%)
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
PP+P ++ P PP P+ P + SA A ++S P PP
Sbjct: 169 PPTP------SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATT 222
Query: 541 DLPP-----------PPPPD--RPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLG 587
PP PP P P + + + P+ +P T PS L P +S
Sbjct: 223 PAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPT----PSATTLDPSSASAPP 278
Query: 588 DSWLPRPIPKVPVSAPSSS---DPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLD 644
++ P P AP SS T +T +S P +L P +T S+
Sbjct: 279 ETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVT 338
Query: 645 TSMSMNSSPLVGP 657
T + P P
Sbjct: 339 TQTTTTKQPTSAP 351
Score = 47.0 bits (110), Expect = 8e-05
Identities = 57/239 (23%), Positives = 86/239 (35%), Gaps = 30/239 (12%)
Query: 489 PQASLPPVPPRLDLLPQRVCVPSSASALGTASKA-ASGSLHKDKPL--PVPPTLRDLPPP 545
P + P ++ LP +P +A+ + + S S+ P+ P P PP
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPT 171
Query: 546 PPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSS 605
P P + + P+ P T PS P SS ++ P P AP S
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPT----PSATTQAPPSSSAPPETTAAPPTPPATTPAPPS 227
Query: 606 SDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIK 665
S S P + P P + L +S ++ V P +
Sbjct: 228 S----------------SAPPETTAAPPTPSATTPAPLSSSAPPETT-AVPPTPSATTLD 270
Query: 666 PSSSANAIYSLAARPLPVPKLPPGEQCEGEEDT---EYMTPSSRP--LRPLDTSQSSRA 719
PSS++ + AA P P P ++T TP+S P L P DTS++S A
Sbjct: 271 PSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP-DTSETSAA 328
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/193 (23%), Positives = 67/193 (34%), Gaps = 26/193 (13%)
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
PP+P ++ P PP P+ P + SA A ++S P PP
Sbjct: 169 PPTP------SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATT 222
Query: 541 DLPP-----------PPPPD--RPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLG 587
PP PP P P + + + P+ +P T PS L P +S
Sbjct: 223 PAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPT----PSATTLDPSSASAPP 278
Query: 588 DSWLPRPIPKVPVSAPSSS---DPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLD 644
++ P P AP SS T +T +S P +L P +T S+
Sbjct: 279 ETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVT 338
Query: 645 TSMSMNSSPLVGP 657
T + P P
Sbjct: 339 TQTTTTKQPTSAP 351
Score = 47.0 bits (110), Expect = 8e-05
Identities = 57/239 (23%), Positives = 86/239 (35%), Gaps = 30/239 (12%)
Query: 489 PQASLPPVPPRLDLLPQRVCVPSSASALGTASKA-ASGSLHKDKPL--PVPPTLRDLPPP 545
P + P ++ LP +P +A+ + + S S+ P+ P P PP
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPT 171
Query: 546 PPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSS 605
P P + + P+ P T PS P SS ++ P P AP S
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPT----PSATTQAPPSSSAPPETTAAPPTPPATTPAPPS 227
Query: 606 SDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIK 665
S S P + P P + L +S ++ V P +
Sbjct: 228 S----------------SAPPETTAAPPTPSATTPAPLSSSAPPETT-AVPPTPSATTLD 270
Query: 666 PSSSANAIYSLAARPLPVPKLPPGEQCEGEEDT---EYMTPSSRP--LRPLDTSQSSRA 719
PSS++ + AA P P P ++T TP+S P L P DTS++S A
Sbjct: 271 PSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP-DTSETSAA 328
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 48.9 bits (115), Expect = 2e-05
Identities = 46/193 (23%), Positives = 67/193 (34%), Gaps = 26/193 (13%)
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
PP+P ++ P PP P+ P + SA A ++S P PP
Sbjct: 169 PPTP------SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATT 222
Query: 541 DLPP-----------PPPPD--RPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLG 587
PP PP P P + + + P+ +P T PS L P +S
Sbjct: 223 PAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPT----PSATTLDPSSASAPP 278
Query: 588 DSWLPRPIPKVPVSAPSSS---DPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLD 644
++ P P AP SS T +T +S P +L P +T S+
Sbjct: 279 ETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVT 338
Query: 645 TSMSMNSSPLVGP 657
T + P P
Sbjct: 339 TQTTTTKQPTSAP 351
Score = 47.0 bits (110), Expect = 8e-05
Identities = 57/239 (23%), Positives = 86/239 (35%), Gaps = 30/239 (12%)
Query: 489 PQASLPPVPPRLDLLPQRVCVPSSASALGTASKA-ASGSLHKDKPL--PVPPTLRDLPPP 545
P + P ++ LP +P +A+ + + S S+ P+ P P PP
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPT 171
Query: 546 PPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSS 605
P P + + P+ P T PS P SS ++ P P AP S
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPT----PSATTQAPPSSSAPPETTAAPPTPPATTPAPPS 227
Query: 606 SDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIK 665
S S P + P P + L +S ++ V P +
Sbjct: 228 S----------------SAPPETTAAPPTPSATTPAPLSSSAPPETT-AVPPTPSATTLD 270
Query: 666 PSSSANAIYSLAARPLPVPKLPPGEQCEGEEDT---EYMTPSSRP--LRPLDTSQSSRA 719
PSS++ + AA P P P ++T TP+S P L P DTS++S A
Sbjct: 271 PSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP-DTSETSAA 328
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/286 (25%), Positives = 102/286 (35%), Gaps = 34/286 (11%)
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
PP PF + PQAS P L P +S + S S +++PLP P
Sbjct: 314 PPQPFGLPPQASQGQAP--LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 371
Query: 541 DLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVP--------SSRLGDSWLP 592
PPP + A + P P LPP P S+ S P
Sbjct: 372 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP 431
Query: 593 RPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPS-------QMEPRPD------VPRLGS 639
P+ +P S P S P LT +LP S Q+ P+P VP
Sbjct: 432 PPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 491
Query: 640 TFSLDTSMSMNSSPL-VGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDT 698
+ T S ++ P G P ++S +I ++ PLP ++ E + E+
Sbjct: 492 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKE-EALDDAEEP 550
Query: 699 EYMTPSSRPLRPLDT--------SQSSRAC-DCDQQIDSCTYEAMY 735
E P R P T SQS+R D+ +SC +Y
Sbjct: 551 ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLY 596
Score = 44.3 bits (103), Expect = 5e-04
Identities = 53/217 (24%), Positives = 83/217 (38%), Gaps = 35/217 (16%)
Query: 479 ERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPT 538
+RPPSP + PP+ P + ++ +A A LH P P P +
Sbjct: 255 QRPPSPHPPPHPSPHPPLQPL-----------TGSAGQPSAPSHAQPPLHGQGP-PGPHS 302
Query: 539 LRDLP--PPPPPDRPYSVGAESRPQRRPLPCTPGDC-PSRDKLPPVPSSRLGDSWLPR-- 593
L+ P P P +P+ + ++ + PL +P P P S L PR
Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362
Query: 594 PIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSP 653
P+P P++ P P T P P P + S + SMN++
Sbjct: 363 PLPPAPLAMPHIKPPPT-------------TPIPQLPAPQAHKHPPHLSGPSPFSMNAN- 408
Query: 654 LVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGE 690
L P P +KP SS + + +A P P+ +P +
Sbjct: 409 LPPP----PALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441
Score = 37.7 bits (86), Expect = 0.049
Identities = 60/258 (23%), Positives = 88/258 (34%), Gaps = 51/258 (19%)
Query: 452 SPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQ-ASLPPVPPRLDL---LPQRV 507
SP+ D +D +++ A+ +P + P +S PP P+L P
Sbjct: 158 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSAT 217
Query: 508 CVPSSASALGTASKAASG-----------------SLHKDKP-LPVPPTLRDLPPPPPPD 549
VP S TAS+A + +LH +P P PP P P PP
Sbjct: 218 AVPPQGSP--TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP---PHPSPHPPL 272
Query: 550 RPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPW 609
+P + G+ +P P P P + PP P S L P P P P +
Sbjct: 273 QPLT-GSAGQPS-APSHAQP---PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 327
Query: 610 TGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSS 669
T+ P+ P + S +L + PL P IKP +
Sbjct: 328 QAPLGTS--------PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 379
Query: 670 ANAIYSLAARPLPVPKLP 687
P+P+LP
Sbjct: 380 T-----------PIPQLP 386
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/286 (25%), Positives = 102/286 (35%), Gaps = 34/286 (11%)
Query: 481 PPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLR 540
PP PF + PQAS P L P +S + S S +++PLP P
Sbjct: 868 PPQPFGLPPQASQGQAP--LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 925
Query: 541 DLPPPPPPDRPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVP--------SSRLGDSWLP 592
PPP + A + P P LPP P S+ S P
Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP 985
Query: 593 RPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPS-------QMEPRPD------VPRLGS 639
P+ +P S P S P LT +LP S Q+ P+P VP
Sbjct: 986 PPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045
Query: 640 TFSLDTSMSMNSSPL-VGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDT 698
+ T S ++ P G P ++S +I ++ PLP ++ E + E+
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKE-EALDDAEEP 1104
Query: 699 EYMTPSSRPLRPLDT--------SQSSRAC-DCDQQIDSCTYEAMY 735
E P R P T SQS+R D+ +SC +Y
Sbjct: 1105 ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLY 1150
Score = 44.3 bits (103), Expect = 5e-04
Identities = 53/217 (24%), Positives = 83/217 (38%), Gaps = 35/217 (16%)
Query: 479 ERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPT 538
+RPPSP + PP+ P + ++ +A A LH P P P +
Sbjct: 809 QRPPSPHPPPHPSPHPPLQPL-----------TGSAGQPSAPSHAQPPLHGQGP-PGPHS 856
Query: 539 LRDLP--PPPPPDRPYSVGAESRPQRRPLPCTPGDC-PSRDKLPPVPSSRLGDSWLPR-- 593
L+ P P P +P+ + ++ + PL +P P P S L PR
Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 916
Query: 594 PIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSP 653
P+P P++ P P T P P P + S + SMN++
Sbjct: 917 PLPPAPLAMPHIKPPPT-------------TPIPQLPAPQAHKHPPHLSGPSPFSMNAN- 962
Query: 654 LVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGE 690
L P P +KP SS + + +A P P+ +P +
Sbjct: 963 LPPP----PALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995
Score = 37.7 bits (86), Expect = 0.049
Identities = 60/258 (23%), Positives = 88/258 (34%), Gaps = 51/258 (19%)
Query: 452 SPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQ-ASLPPVPPRLDL---LPQRV 507
SP+ D +D +++ A+ +P + P +S PP P+L P
Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSAT 771
Query: 508 CVPSSASALGTASKAASG-----------------SLHKDKP-LPVPPTLRDLPPPPPPD 549
VP S TAS+A + +LH +P P PP P P PP
Sbjct: 772 AVPPQGSP--TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP---PHPSPHPPL 826
Query: 550 RPYSVGAESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPW 609
+P + G+ +P P P P + PP P S L P P P P +
Sbjct: 827 QPLT-GSAGQPS-APSHAQP---PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQG 881
Query: 610 TGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSS 669
T+ P+ P + S +L + PL P IKP +
Sbjct: 882 QAPLGTS--------PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 933
Query: 670 ANAIYSLAARPLPVPKLP 687
P+P+LP
Sbjct: 934 T-----------PIPQLP 940
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,621,312
Number of Sequences: 37866
Number of extensions: 2597836
Number of successful extensions: 26345
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 1033
Number of HSP's that attempted gapping in prelim test: 18105
Number of HSP's gapped (non-prelim): 6068
length of query: 906
length of database: 18,247,518
effective HSP length: 111
effective length of query: 795
effective length of database: 14,044,392
effective search space: 11165291640
effective search space used: 11165291640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.