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Search of human proteins with 5174711
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174711 T-box 1 isoform B [Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174711 T-box 1 isoform B [Homo sapiens] 775 0.0
gi|18104950 T-box 1 isoform A [Homo sapiens] 704 0.0
gi|18104952 T-box 1 isoform C [Homo sapiens] 702 0.0
gi|32567784 T-box 10 [Homo sapiens] 382 e-106
gi|117676399 T-box transcription factor TBX20 [Homo sapiens] 256 2e-68
gi|18129690 T-box 4 [Homo sapiens] 256 3e-68
gi|197333868 T-box 2 [Homo sapiens] 249 4e-66
gi|122937456 T-box 18 [Homo sapiens] 245 5e-65
gi|55770860 T-box 15 [Homo sapiens] 244 1e-64
gi|18201896 T-box 5 isoform 2 [Homo sapiens] 242 3e-64
gi|18201892 T-box 5 isoform 1 [Homo sapiens] 242 3e-64
gi|31652232 T-box 5 isoform 1 [Homo sapiens] 242 3e-64
gi|18201894 T-box 5 isoform 3 [Homo sapiens] 239 2e-63
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens] 232 4e-61
gi|158187509 T-box 22 isoform 1 [Homo sapiens] 228 9e-60
gi|18375603 T-box 22 isoform 1 [Homo sapiens] 228 9e-60
gi|47419907 T-box 3 protein isoform 2 [Homo sapiens] 221 1e-57
gi|18201900 T-box 6 [Homo sapiens] 219 4e-57
gi|122937388 MAX gene associated [Homo sapiens] 199 3e-51
gi|7019549 T-box 21 [Homo sapiens] 197 1e-50
gi|158187511 T-box 22 isoform 2 [Homo sapiens] 191 1e-48
gi|22538470 eomesodermin [Homo sapiens] 184 1e-46
gi|5730081 T-box, brain, 1 [Homo sapiens] 176 4e-44
gi|4507339 transcription factor T [Homo sapiens] 172 4e-43
gi|4827024 T-box 19 [Homo sapiens] 169 3e-42
gi|110832843 TBP-associated factor 4 [Homo sapiens] 50 3e-06
gi|39812378 RAN binding protein 9 [Homo sapiens] 49 6e-06
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 49 7e-06
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens] 48 1e-05
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 48 2e-05
>gi|5174711 T-box 1 isoform B [Homo sapiens]
Length = 372
Score = 775 bits (2000), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA
Sbjct: 1 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
Query: 61 PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW
Sbjct: 61 PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
Query: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL
Sbjct: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
Query: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR
Sbjct: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP
Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
Query: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLKPPSKK 360
EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLKPPSKK
Sbjct: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLKPPSKK 360
Query: 361 SESLRPPHCKDT 372
SESLRPPHCKDT
Sbjct: 361 SESLRPPHCKDT 372
>gi|18104950 T-box 1 isoform A [Homo sapiens]
Length = 398
Score = 704 bits (1816), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA
Sbjct: 1 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
Query: 61 PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW
Sbjct: 61 PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
Query: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL
Sbjct: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
Query: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR
Sbjct: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP
Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
Query: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKG 337
EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKG
Sbjct: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKG 337
>gi|18104952 T-box 1 isoform C [Homo sapiens]
Length = 495
Score = 702 bits (1812), Expect = 0.0
Identities = 343/371 (92%), Positives = 345/371 (92%), Gaps = 5/371 (1%)
Query: 1 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA
Sbjct: 1 MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA 60
Query: 61 PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW
Sbjct: 61 PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALW 120
Query: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL
Sbjct: 121 DEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWL 180
Query: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR
Sbjct: 181 VAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPR 240
Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP
Sbjct: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDP 300
Query: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQ-----PGLLDVLLK 355
EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEK Q P +L
Sbjct: 301 EDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKDAAEARREFQRDAGGPAVLGDPAH 360
Query: 356 PPSKKSESLRP 366
PP + L P
Sbjct: 361 PPQLLARVLSP 371
Score = 33.5 bits (75), Expect = 0.32
Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 32/116 (27%)
Query: 17 SLSSLGAAGGF-PGAASPGADPYGPR-----------EPPPPPPRYDPCAA-----AAPG 59
SL G AGG P +PG P P EP P P AA A
Sbjct: 372 SLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPLHHHPYKYPAAAYDHYLGAKS 431
Query: 60 APGPPPPP---------------HAYPFAPAAGAATSAAAEPEGPGASCAAAAKAP 100
P P P P H +P +PAA AA +AAA +A A P
Sbjct: 432 RPAPYPLPGLRGHGYHPHAHPHHHHHPVSPAAAAAAAAAAAAAAANMYSSAGAAPP 487
>gi|32567784 T-box 10 [Homo sapiens]
Length = 385
Score = 382 bits (980), Expect = e-106
Identities = 187/273 (68%), Positives = 216/273 (79%), Gaps = 4/273 (1%)
Query: 64 PPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEF 123
P P + + P G+ + GA A KN +V+ V+VQLEMK LW+EF
Sbjct: 19 PLPTTSSGWEPRLGSPFPSGPCTSSTGAQAVAEPTGQGPKNPRVSRVTVQLEMKPLWEEF 78
Query: 124 NQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAG 183
NQLGTEMIVTKAGRRMFP FQVK+ GMD +ADY LLMDF+P+DDKRYRYAFHSS+WLVAG
Sbjct: 79 NQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAG 138
Query: 184 KADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHV 243
KADPATPGRVH+HPDSPAKGAQWM+QIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHV
Sbjct: 139 KADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHV 198
Query: 244 VYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDW 303
V+VDPRKDSE+YA+ENFK+F+F ET+FTAVTAYQNHRITQLKIASNPFAKGFR+ D + W
Sbjct: 199 VFVDPRKDSERYAQENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESDLDSW 258
Query: 304 PRNHRPGALPLMSAFARSRNPVASPTQPSGTEK 336
P R PL+S ARS + ++ T++
Sbjct: 259 PVAPR----PLLSVPARSHSSLSPCVLKGATDR 287
>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
Length = 447
Score = 256 bits (655), Expect = 2e-68
Identities = 131/237 (55%), Positives = 165/237 (69%), Gaps = 12/237 (5%)
Query: 73 APAAGAATSAAAEPEGPGASCAAAAKA-----------PVKKNAKVAGVSVQLEMKALWD 121
A G TS A E G S ++ + + P+ + ++A ++ LE K LWD
Sbjct: 52 AQPLGELTSLDAHGEFGGGSGSSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKELWD 111
Query: 122 EFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLV 181
+F++LGTEMI+TK+GRRMFPT +V G+DP A Y++LMD VPVD+KRYRYA+H SSWLV
Sbjct: 112 KFHELGTEMIITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLV 171
Query: 182 AGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRF 241
AGKADP P R++ HPDSP G Q +KQ+VSF+K+KLTNN LD +GHIILNSMH+YQPR
Sbjct: 172 AGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRV 231
Query: 242 HVV-YVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
H++ D E F+TF+F ET FTAVTAYQN IT+LKI SNPFAKGFRD
Sbjct: 232 HIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRD 288
>gi|18129690 T-box 4 [Homo sapiens]
Length = 545
Score = 256 bits (653), Expect = 3e-68
Identities = 133/250 (53%), Positives = 168/250 (67%), Gaps = 16/250 (6%)
Query: 60 APGPPPPPHAYPFAP-----AAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQL 114
APGP + AP A G + +A P GPGA AAA A + + V L
Sbjct: 16 APGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAAAAA----EQTIENIKVGL 71
Query: 115 EMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAF 174
K LW +F++ GTEMI+TKAGRRMFP+++VK+ GM+P Y+LL+D VP DD RY++
Sbjct: 72 HEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRYKFC- 130
Query: 175 HSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSM 234
+ W+VAGKA+PA PGR++ HPDSPA GA WM+Q+VSF KLKLTNN LD GHIILNSM
Sbjct: 131 -DNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSM 189
Query: 235 HRYQPRFHVVYVDPRKDSEKYAEEN--FKTFVFEETRFTAVTAYQNHRITQLKIASNPFA 292
H+YQPR H+V D ++ + +N F T VF ET F +VT+YQNH+ITQLKI +NPFA
Sbjct: 190 HKYQPRLHIVKAD---ENNAFGSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFA 246
Query: 293 KGFRDCDPED 302
KGFR D D
Sbjct: 247 KGFRGSDDSD 256
>gi|197333868 T-box 2 [Homo sapiens]
Length = 712
Score = 249 bits (635), Expect = 4e-66
Identities = 134/258 (51%), Positives = 168/258 (65%), Gaps = 13/258 (5%)
Query: 48 PRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEP--------EGPGASCAAAAKA 99
P + P A PGA P P A AA AA +AAAE P A+ + K+
Sbjct: 35 PSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKS 94
Query: 100 PVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLL 159
++ V LE K LWD+F++LGTEM++TK+GRRMFP F+V++ G+D A Y+LL
Sbjct: 95 LEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILL 154
Query: 160 MDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLT 219
MD V DD RY+ FH+S W+VAGKADP P R++ HPDSPA G QWM + V+F KLKLT
Sbjct: 155 MDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLT 212
Query: 220 NNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNH 279
NN+ D +G ILNSMH+YQPRFH+V + D K F+T+VF ET F AVTAYQN
Sbjct: 213 NNISDKHGFTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYVFPETDFIAVTAYQND 269
Query: 280 RITQLKIASNPFAKGFRD 297
+ITQLKI +NPFAKGFRD
Sbjct: 270 KITQLKIDNNPFAKGFRD 287
Score = 30.0 bits (66), Expect = 3.5
Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 15/119 (12%)
Query: 1 MHFSTVTRDMEAFTASSLSSLGAA--------GGFPG-AASPGADPYGPREPP-----PP 46
+H T AF+A + L A+ GG PG AA A GP P
Sbjct: 491 LHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPF 550
Query: 47 PPRYDPCAAAAPGAPGPP-PPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN 104
P A+ G P P YP+ A AA +A+A P A+ AAAA + ++
Sbjct: 551 PFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRS 609
>gi|122937456 T-box 18 [Homo sapiens]
Length = 607
Score = 245 bits (625), Expect = 5e-65
Identities = 135/280 (48%), Positives = 160/280 (57%), Gaps = 14/280 (5%)
Query: 25 GGFPGAASPGADPYGPREPPPPPPRYDPCAAAAP---GAPGPPPPPHAYPFAPAAGAATS 81
GG G G PPP P + A GA G F A S
Sbjct: 58 GGGAGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDG----FQQGASPLAS 113
Query: 82 AAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFP 141
P+G A A P+ V L+ LW F+++GTEMI+TKAGRRMFP
Sbjct: 114 PGGSPKGSPARSLARPGTPLPSPQ---APRVDLQGAELWKRFHEIGTEMIITKAGRRMFP 170
Query: 142 TFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPA 201
+VK+ G+DP Y + MD VPVD+KRYRY +HSS W+VAG AD P RV+ HPDSPA
Sbjct: 171 AMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPA 230
Query: 202 KGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKY----AE 257
G WM+Q++SFDKLKLTNN LDD GHIIL+SMH+YQPR HV+ D D +
Sbjct: 231 SGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSG 290
Query: 258 ENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
E K F F ET FT VTAYQN +IT+LKI NPFAKGFRD
Sbjct: 291 EGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRD 330
>gi|55770860 T-box 15 [Homo sapiens]
Length = 496
Score = 244 bits (622), Expect = 1e-64
Identities = 133/262 (50%), Positives = 159/262 (60%), Gaps = 11/262 (4%)
Query: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169
+ V+L+ LW F+ +GTEMI+TKAGRRMFP +VK+ G+DP Y + MD VPVD+KR
Sbjct: 7 IQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKR 66
Query: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229
YRY +HSS W+VAG AD P RV+ HPDS A G WM+Q+VSFDKLKLTNN LDD GHI
Sbjct: 67 YRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHI 126
Query: 230 ILNSMHRYQPRFHVVYVDPRKDSEKY----AEENFKTFVFEETRFTAVTAYQNHRITQLK 285
IL+SMH+YQPR HV+ D D + KTF F ET FT VTAYQN +IT+LK
Sbjct: 127 ILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLK 186
Query: 286 IASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGS-G 344
I NPFAKGFRD +R G +M +A R PV + T T GS G
Sbjct: 187 IDRNPFAKGFRDSG------RNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTG 240
Query: 345 LQPGLLDVLLKPPSKKSESLRP 366
P PS S L P
Sbjct: 241 TSPTTSSTGTPSPSASSHLLSP 262
>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
Length = 349
Score = 242 bits (618), Expect = 3e-64
Identities = 131/266 (49%), Positives = 175/266 (65%), Gaps = 15/266 (5%)
Query: 89 PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
P ++ A +K+P A + G+ V L + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 28 PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
Query: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
+VK+ G++P Y+LLMD VP DD RY++A + W V GKA+PA PGR++ HPDSPA G
Sbjct: 88 KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
Query: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
A WM+Q+VSF KLKLTNN LD GHIILNSMH+YQPR H+V D ++ + +N F
Sbjct: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
Query: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR D + R R + P++ +
Sbjct: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261
Query: 320 RSRNPVASPTQPSGTEKGLVTEGSGL 345
R VAS P +E ++ S L
Sbjct: 262 TVRQKVASNHSPFSSESRALSTSSNL 287
>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 242 bits (618), Expect = 3e-64
Identities = 131/266 (49%), Positives = 175/266 (65%), Gaps = 15/266 (5%)
Query: 89 PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
P ++ A +K+P A + G+ V L + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 28 PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
Query: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
+VK+ G++P Y+LLMD VP DD RY++A + W V GKA+PA PGR++ HPDSPA G
Sbjct: 88 KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
Query: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
A WM+Q+VSF KLKLTNN LD GHIILNSMH+YQPR H+V D ++ + +N F
Sbjct: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
Query: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR D + R R + P++ +
Sbjct: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261
Query: 320 RSRNPVASPTQPSGTEKGLVTEGSGL 345
R VAS P +E ++ S L
Sbjct: 262 TVRQKVASNHSPFSSESRALSTSSNL 287
>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
Length = 518
Score = 242 bits (618), Expect = 3e-64
Identities = 131/266 (49%), Positives = 175/266 (65%), Gaps = 15/266 (5%)
Query: 89 PGASCAAAAKAPVKKNAK-----VAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTF 143
P ++ A +K+P A + G+ V L + LW +F+++GTEMI+TKAGRRMFP++
Sbjct: 28 PESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSY 87
Query: 144 QVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKG 203
+VK+ G++P Y+LLMD VP DD RY++A + W V GKA+PA PGR++ HPDSPA G
Sbjct: 88 KVKVTGLNPKTKYILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATG 145
Query: 204 AQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FK 261
A WM+Q+VSF KLKLTNN LD GHIILNSMH+YQPR H+V D ++ + +N F
Sbjct: 146 AHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFC 202
Query: 262 TFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFA 319
T VF ET F AVT+YQNH+ITQLKI +NPFAKGFR D + R R + P++ +
Sbjct: 203 THVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-S 261
Query: 320 RSRNPVASPTQPSGTEKGLVTEGSGL 345
R VAS P +E ++ S L
Sbjct: 262 TVRQKVASNHSPFSSESRALSTSSNL 287
>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
Length = 468
Score = 239 bits (611), Expect = 2e-63
Identities = 126/241 (52%), Positives = 165/241 (68%), Gaps = 10/241 (4%)
Query: 109 GVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDK 168
G+ V L + LW +F+++GTEMI+TKAGRRMFP+++VK+ G++P Y+LLMD VP DD
Sbjct: 3 GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH 62
Query: 169 RYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH 228
RY++A + W V GKA+PA PGR++ HPDSPA GA WM+Q+VSF KLKLTNN LD GH
Sbjct: 63 RYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGH 120
Query: 229 IILNSMHRYQPRFHVVYVDPRKDSEKYAEEN--FKTFVFEETRFTAVTAYQNHRITQLKI 286
IILNSMH+YQPR H+V D ++ + +N F T VF ET F AVT+YQNH+ITQLKI
Sbjct: 121 IILNSMHKYQPRLHIVKAD---ENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKI 177
Query: 287 ASNPFAKGFRDCDPEDWPRNHRPGA--LPLMSAFARSRNPVASPTQPSGTEKGLVTEGSG 344
+NPFAKGFR D + R R + P++ + R VAS P +E ++ S
Sbjct: 178 ENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPR-STVRQKVASNHSPFSSESRALSTSSN 236
Query: 345 L 345
L
Sbjct: 237 L 237
>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
Length = 723
Score = 232 bits (592), Expect = 4e-61
Identities = 111/186 (59%), Positives = 140/186 (75%), Gaps = 5/186 (2%)
Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
V LE K LWD+F++ GTEM++TK+GRRMFP F+V+ G+D A Y+LLMD + DD RY+
Sbjct: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164
Query: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIIL 231
FH+S W+VAGKADP P R++ HPDSPA G QWM ++V+F KLKLTNN+ D +G IL
Sbjct: 165 --FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTIL 222
Query: 232 NSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPF 291
NSMH+YQPRFH+V + D K F+T++F ET F AVTAYQN +ITQLKI +NPF
Sbjct: 223 NSMHKYQPRFHIVRAN---DILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPF 279
Query: 292 AKGFRD 297
AKGFRD
Sbjct: 280 AKGFRD 285
>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 228 bits (580), Expect = 9e-60
Identities = 128/301 (42%), Positives = 167/301 (55%), Gaps = 14/301 (4%)
Query: 60 APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKAL 119
A G P P + +A+S G G S ++ + + ++L+ L
Sbjct: 51 AAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---------SESLEEKDIQMELQGSEL 101
Query: 120 WDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSW 179
W F+ +GTEMI+TKAGRRMFP+ +VK+ G+DP Y + +D VPVD KRYRY +HSS W
Sbjct: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161
Query: 180 LVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 238
+VAG D R + HPDSP G WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+
Sbjct: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221
Query: 239 PRFHVVYVDPRKD---SEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295
PR HV+ D + E KTF F+ET FT VTAYQN +IT+LKI NPFAKGF
Sbjct: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281
Query: 296 RDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLK 355
RD + P +F + TQ SG+ SG P L+ LL
Sbjct: 282 RDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQ-SGSSGSSPVTSSGGAPSPLNSLLS 340
Query: 356 P 356
P
Sbjct: 341 P 341
>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
Length = 520
Score = 228 bits (580), Expect = 9e-60
Identities = 128/301 (42%), Positives = 167/301 (55%), Gaps = 14/301 (4%)
Query: 60 APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKAL 119
A G P P + +A+S G G S ++ + + ++L+ L
Sbjct: 51 AAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---------SESLEEKDIQMELQGSEL 101
Query: 120 WDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSW 179
W F+ +GTEMI+TKAGRRMFP+ +VK+ G+DP Y + +D VPVD KRYRY +HSS W
Sbjct: 102 WKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQW 161
Query: 180 LVAGKADP-ATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQ 238
+VAG D R + HPDSP G WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+
Sbjct: 162 MVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYK 221
Query: 239 PRFHVVYVDPRKD---SEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295
PR HV+ D + E KTF F+ET FT VTAYQN +IT+LKI NPFAKGF
Sbjct: 222 PRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGF 281
Query: 296 RDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLK 355
RD + P +F + TQ SG+ SG P L+ LL
Sbjct: 282 RDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQ-SGSSGSSPVTSSGGAPSPLNSLLS 340
Query: 356 P 356
P
Sbjct: 341 P 341
>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
Length = 743
Score = 221 bits (562), Expect = 1e-57
Identities = 111/206 (53%), Positives = 140/206 (67%), Gaps = 25/206 (12%)
Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
V LE K LWD+F++ GTEM++TK+GRRMFP F+V+ G+D A Y+LLMD + DD RY+
Sbjct: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164
Query: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNG---- 227
FH+S W+VAGKADP P R++ HPDSPA G QWM ++V+F KLKLTNN+ D +G
Sbjct: 165 --FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLA 222
Query: 228 ----------------HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFT 271
ILNSMH+YQPRFH+V + D K F+T++F ET F
Sbjct: 223 FPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYLFPETEFI 279
Query: 272 AVTAYQNHRITQLKIASNPFAKGFRD 297
AVTAYQN +ITQLKI +NPFAKGFRD
Sbjct: 280 AVTAYQNDKITQLKIDNNPFAKGFRD 305
>gi|18201900 T-box 6 [Homo sapiens]
Length = 436
Score = 219 bits (557), Expect = 4e-57
Identities = 129/285 (45%), Positives = 166/285 (58%), Gaps = 28/285 (9%)
Query: 20 SLGAAGGFPGAASPGADPYGP-------REPPPPPPRYDPCAAAAPGAPGPPPPPHAYPF 72
SLGA G G A PGAD P R P P+ D + AP P
Sbjct: 10 SLGA-GYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTLAAHPPLPL 68
Query: 73 APAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIV 132
P A A + PE + + GVS+ LE + LW EF+ +GTEMI+
Sbjct: 69 LPPAMGTEPAPSAPEALHS---------------LPGVSLSLENRELWKEFSSVGTEMII 113
Query: 133 TKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGR 192
TKAGRRMFP +V + G+DP A Y+ L+D +PVD RYR+ W +GKA+P P R
Sbjct: 114 TKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRW--QGRRWEPSGKAEPRLPDR 171
Query: 193 VHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDS 252
V+ HPDSPA GA WM+Q VSF ++KLTN+ LD +GH+IL+SMH+YQPR H+V + S
Sbjct: 172 VYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRA-AQLCS 230
Query: 253 EKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
+ + +F F ET F +VTAYQN +ITQLKIA+NPFAKGFR+
Sbjct: 231 QHWG--GMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRE 273
>gi|122937388 MAX gene associated [Homo sapiens]
Length = 3114
Score = 199 bits (507), Expect = 3e-51
Identities = 121/290 (41%), Positives = 159/290 (54%), Gaps = 20/290 (6%)
Query: 74 PAAGAATSAAAEPEGPGASCAAAAKAPVKKNAK--------VAGVSVQLEMKALWDEFNQ 125
P G + A++ +PVK K V G++V L+ ++W+EF
Sbjct: 31 PGNGKTDQGILVTNQDACALASSVSSPVKSKGKICLPADCTVGGITVTLDNNSMWNEFYH 90
Query: 126 LGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKA 185
TEMI+TK GRRMFP + + G+D Y+L+MD PVD+ RY++ + W +GKA
Sbjct: 91 RSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDNHRYKW--NGRWWEPSGKA 148
Query: 186 DPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVY 245
+P GRV HP+SP+ G WM Q VSF KLKLTNN LD GHIIL+SMHRY PR H+V
Sbjct: 149 EPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILHSMHRYLPRLHLVP 208
Query: 246 VDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPR 305
+ + + TF F +T F AVTAYQN +ITQLKI NPFAKGFRD + P+
Sbjct: 209 AEKAVEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLNNKPQ 268
Query: 306 NHRPGALPLMSAFARSRNPVASPTQPSGTEKGLVTEGSG--LQPGLLDVL 353
R G S + + S + +TEG G +QPG LD L
Sbjct: 269 --RDGKQ------KNSSDQEGNNISSSSGHRVRLTEGQGSEIQPGDLDPL 310
>gi|7019549 T-box 21 [Homo sapiens]
Length = 535
Score = 197 bits (501), Expect = 1e-50
Identities = 125/287 (43%), Positives = 156/287 (54%), Gaps = 25/287 (8%)
Query: 25 GGFPGAASPGADPYGPREPPPP---------PPRYDPCAAAAPGAPGP-PPPPHAYPFAP 74
GG G+ PG G P PP PPR P AA PGA PPP A + P
Sbjct: 51 GGSLGSPYPG----GALVPAPPSRFLGAYAYPPR--PQAAGFPGAGESFPPPADAEGYQP 104
Query: 75 AAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTK 134
G A PG A A ++ + K+ V L LW +FNQ TEMI+TK
Sbjct: 105 GEGYAAPDPRAGLYPGPREDYALPAGLEVSGKLR---VALNNHLLWSKFNQHQTEMIITK 161
Query: 135 AGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPG-RV 193
GRRMFP + G++P + Y + +D V VD +RY S W+ GKA+ + PG R+
Sbjct: 162 QGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRY--QSGKWVQCGKAEGSMPGNRL 219
Query: 194 HYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNG---HIILNSMHRYQPRFHVVYVDPRK 250
+ HPDSP GA WM+Q VSF KLKLTNN N I+L S+H+YQPR H+V V+ +
Sbjct: 220 YVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGE 279
Query: 251 DSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
N F F+ET+F AVTAYQN ITQLKI +NPFAKGFR+
Sbjct: 280 PEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRE 326
>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
Length = 400
Score = 191 bits (484), Expect = 1e-48
Identities = 104/222 (46%), Positives = 130/222 (58%), Gaps = 5/222 (2%)
Query: 139 MFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADP-ATPGRVHYHP 197
MFP+ +VK+ G+DP Y + +D VPVD KRYRY +HSS W+VAG D R + HP
Sbjct: 1 MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60
Query: 198 DSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKD---SEK 254
DSP G WM+QI+SFD++KLTNN +DD GHIIL SMH+Y+PR HV+ D +
Sbjct: 61 DSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQS 120
Query: 255 YAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPL 314
E KTF F+ET FT VTAYQN +IT+LKI NPFAKGFRD + P
Sbjct: 121 LPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPW 180
Query: 315 MSAFARSRNPVASPTQPSGTEKGLVTEGSGLQPGLLDVLLKP 356
+F + TQ SG+ SG P L+ LL P
Sbjct: 181 RPSFTLDFKTFGADTQ-SGSSGSSPVTSSGGAPSPLNSLLSP 221
>gi|22538470 eomesodermin [Homo sapiens]
Length = 686
Score = 184 bits (467), Expect = 1e-46
Identities = 117/297 (39%), Positives = 153/297 (51%), Gaps = 29/297 (9%)
Query: 27 FPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAE 85
FP A+ GA P+GP P P RY + PG P PP F P AGA + A
Sbjct: 163 FPYQAAAGA-PHGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGS 221
Query: 86 PEG-------------------PGASCAAAAKAPVKKNAKVAG--VSVQLEMKALWDEFN 124
G PGA+ A + +G V L + LW +F+
Sbjct: 222 SGGGGGPGTYQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFH 281
Query: 125 QLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGK 184
+ TEMI+TK GRRMFP + G++P A Y + ++ V D +R F W+ GK
Sbjct: 282 RHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGK 339
Query: 185 ADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH---IILNSMHRYQPR 240
AD G +++ HP+SP G+ WM+Q +SF KLKLTNN +N + I+L S+H+YQPR
Sbjct: 340 ADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPR 399
Query: 241 FHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 297
H+V V + +TF F ET+F AVTAYQN ITQLKI NPFAKGFRD
Sbjct: 400 LHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 456
Score = 30.0 bits (66), Expect = 3.5
Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 20 SLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAP----GPPPPPHAYPFAPA 75
S A G P AAS GA + A A PG P G P P A A
Sbjct: 60 SCEAVSGEPAAASAGAPAAMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAA 119
Query: 76 AGAATSAAA 84
A AA +AAA
Sbjct: 120 AAAAAAAAA 128
>gi|5730081 T-box, brain, 1 [Homo sapiens]
Length = 682
Score = 176 bits (445), Expect = 4e-44
Identities = 113/267 (42%), Positives = 146/267 (54%), Gaps = 33/267 (12%)
Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
V L + LW +F++ TEMI+TK GRRMFP + G+DP A Y + +D + D +R
Sbjct: 206 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWR 265
Query: 172 YAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNN--LLDDNGH 228
F W+ GKAD G RV+ HPDSP GA WM+Q +SF KLKLTNN ++NG
Sbjct: 266 --FQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQ 323
Query: 229 -IILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIA 287
++L S+H+YQPR HVV V+ + +TF F ET+F AVTAYQN ITQLKI
Sbjct: 324 MVVLQSLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKID 383
Query: 288 SNPFAKGFRD--------CD-------PEDWPRNH-RPGALPLM----------SAFARS 321
NPFAKGFRD CD P D PR+ PGA M S +A++
Sbjct: 384 HNPFAKGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGSFLQDQFVSNYAKA 443
Query: 322 R-NPVASPTQPSGTEKGLVTEGSGLQP 347
R +P A GT++ + L P
Sbjct: 444 RFHPGAGAGPGPGTDRSVPHTNGLLSP 470
>gi|4507339 transcription factor T [Homo sapiens]
Length = 435
Score = 172 bits (436), Expect = 4e-43
Identities = 92/186 (49%), Positives = 114/186 (61%), Gaps = 10/186 (5%)
Query: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171
V LE LW F +L EMIVTK GRRMFP +V + G+DP A Y L+DFV D+ R++
Sbjct: 44 VGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWK 103
Query: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIIL 231
Y + W+ GK +P P V+ HPDSP GA WMK VSF K+KLTN L+ G I+L
Sbjct: 104 YV--NGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNK-LNGGGQIML 160
Query: 232 NSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPF 291
NS+H+Y+PR H+V V + + F ET+F AVTAYQN IT LKI NPF
Sbjct: 161 NSLHKYEPRIHIVRVGG-------PQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPF 213
Query: 292 AKGFRD 297
AK F D
Sbjct: 214 AKAFLD 219
>gi|4827024 T-box 19 [Homo sapiens]
Length = 448
Score = 169 bits (429), Expect = 3e-42
Identities = 92/198 (46%), Positives = 119/198 (60%), Gaps = 14/198 (7%)
Query: 110 VSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKR 169
+ + LE LW F ++ EMIVTK GRRMFP ++ + G+DP A Y LL+DFVP D R
Sbjct: 41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100
Query: 170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHI 229
++Y + W+ AGK + ++ V+ HPDSP GA WMK +SF K+KLTN L+ G I
Sbjct: 101 WKYV--NGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQI 157
Query: 230 ILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASN 289
+LNS+H+Y+P+ H+V V A F ET+F AVTAYQN IT LKI N
Sbjct: 158 MLNSLHKYEPQVHIVRVGS-------AHRMVTNCSFPETQFIAVTAYQNEEITALKIKYN 210
Query: 290 PFAKGFRDCDPEDWPRNH 307
PFAK F D RNH
Sbjct: 211 PFAKAFLDAK----ERNH 224
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 50.1 bits (118), Expect = 3e-06
Identities = 41/94 (43%), Positives = 43/94 (45%), Gaps = 16/94 (17%)
Query: 23 AAGGFPGAASPGA--DPYGPREPPPPPPRYDPCAAAAPGAP-GPP------PPPHAYPFA 73
AA P A SP A P P PPPPP A PG P GPP PPP A
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306
Query: 74 PAAGAATS---AAAEPEG----PGASCAAAAKAP 100
+AGAA + AA P G PG AAAA AP
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340
Score = 48.1 bits (113), Expect = 1e-05
Identities = 45/134 (33%), Positives = 52/134 (38%), Gaps = 36/134 (26%)
Query: 2 HFSTVTRDMEAFTASSL-------SSLGAAGGFPGA---ASPGADPY------------G 39
H + T ++ A A +L S GAAG P A +PGA P G
Sbjct: 42 HLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGG 101
Query: 40 PREPPPPPPRYDPCAAAAPGAPG----PPPPPHAYPFAPAAGAATSAA---------AEP 86
P+ P PP PR P A P P PPP A AP AA AA A+P
Sbjct: 102 PQRPGPPSPRR-PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
Query: 87 EGPGASCAAAAKAP 100
GP A A A P
Sbjct: 161 AGPAALAARAGPGP 174
Score = 46.2 bits (108), Expect = 5e-05
Identities = 45/118 (38%), Positives = 49/118 (41%), Gaps = 16/118 (13%)
Query: 12 AFTASSLSSLGAAG--GFPGAASPGA----DPYGPREPPPPPPRYDPCAAAAPGAPG--P 63
A A SL + G A P A+PG P+ PP P P AA AP AP P
Sbjct: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270
Query: 64 PPPPH-----AYPFAPAAGAATSAAAEPEGPGA---SCAAAAKAPVKKNAKVAGVSVQ 113
PPPP A P AG T+A A P A A AA AP AGVS Q
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQ 328
Score = 33.5 bits (75), Expect = 0.32
Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 10/95 (10%)
Query: 20 SLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAA 79
S G+ P AA+ A P P P AA A PGP P P P
Sbjct: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP-------- 184
Query: 80 TSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQL 114
+P GPGA+ A + + A +V L
Sbjct: 185 --GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL 217
Score = 29.3 bits (64), Expect = 6.0
Identities = 31/115 (26%), Positives = 36/115 (31%), Gaps = 28/115 (24%)
Query: 13 FTASSLSSLGAAGGFPGAASPGADPYGPREPPPPP-----------------PRYDPCAA 55
F ++ AA P A +P A P PPP P P P AA
Sbjct: 243 FVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAA 302
Query: 56 AAPG-----------APGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKA 99
A G A G P P AA AA + + E P AA A
Sbjct: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 49.3 bits (116), Expect = 6e-06
Identities = 38/92 (41%), Positives = 41/92 (44%), Gaps = 13/92 (14%)
Query: 19 SSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAG- 77
S G+ GG G GA PPPPP P A AAP P PPPPP A APA+G
Sbjct: 46 SPAGSPGGGAGGEGLGAAAAALLLHPPPPP---PPATAAPPPPPPPPPPPASAAAPASGP 102
Query: 78 -AATSAAAEPEGPG--------ASCAAAAKAP 100
A AA P G A +AAA P
Sbjct: 103 PAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/90 (42%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 22 GAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATS 81
GA G GAA+ + PPPPPP A AAP P PPPPP A APA+G
Sbjct: 54 GAGGEGLGAAAAALLLH---PPPPPPP-----ATAAPPPPPPPPPPPASAAAPASGPPA- 104
Query: 82 AAAEPEGPGASCAAAAKAPVKKNAKVAGVS 111
P G A A AP A VAG S
Sbjct: 105 ----PPGLAAGPGPAGGAPTP--ALVAGSS 128
Score = 33.1 bits (74), Expect = 0.41
Identities = 25/73 (34%), Positives = 29/73 (39%), Gaps = 19/73 (26%)
Query: 42 EPPPPPPRYDPCAAAAPGAPGPPPPPHAY--------PFAPAAGAATSAAAEP------E 87
+PPPPPP+ PPPP A P PA A +S A P E
Sbjct: 4 QPPPPPPQQQQQQQQLS-----PPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58
Query: 88 GPGASCAAAAKAP 100
G GA+ AA P
Sbjct: 59 GLGAAAAALLLHP 71
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 48.9 bits (115), Expect = 7e-06
Identities = 31/78 (39%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 27 FPGAASPGADPYGPREPPPPPP--RYDPCAAAAPGAPGPPPPPHAYPFAPAA--GAATSA 82
FPG G P GP P PPPP Y P P GPPPPP +P P G +
Sbjct: 279 FPGQPF-GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337
Query: 83 AAEPEGPGASCAAAAKAP 100
A P PG A AP
Sbjct: 338 APPPHLPGPPPGAPPPAP 355
Score = 38.1 bits (87), Expect = 0.013
Identities = 27/67 (40%), Positives = 27/67 (40%), Gaps = 15/67 (22%)
Query: 25 GGFPGAASPGADPY--------GPREPPPP------PPRYDPCAAAAPGAPGPPPPPHAY 70
GG PGA P GP PPPP PPR PG PGPPPP
Sbjct: 200 GGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL 259
Query: 71 PFAPAAG 77
P P AG
Sbjct: 260 P-PPLAG 265
Score = 35.8 bits (81), Expect = 0.064
Identities = 22/67 (32%), Positives = 23/67 (34%), Gaps = 19/67 (28%)
Query: 27 FPGAASPGADPY-------------------GPREPPPPPPRYDPCAAAAPGAPGPPPPP 67
FPG A PG P GP PPPP P A P PPPP
Sbjct: 217 FPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPP 276
Query: 68 HAYPFAP 74
+P P
Sbjct: 277 VLFPGQP 283
Score = 33.9 bits (76), Expect = 0.24
Identities = 25/75 (33%), Positives = 28/75 (37%), Gaps = 7/75 (9%)
Query: 22 GAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAA----APGAP--GPPPPPHAYP-FAP 74
G G P P GP P PP P P A PG P PPP PH P F P
Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363
Query: 75 AAGAATSAAAEPEGP 89
+ ++ GP
Sbjct: 364 PPTNSGMPTSDSRGP 378
Score = 32.7 bits (73), Expect = 0.54
Identities = 28/93 (30%), Positives = 29/93 (31%), Gaps = 30/93 (32%)
Query: 27 FPGAASPGADPYGPREPP----PPPP-------------RYD--PCAAAAPGAP------ 61
FP +P P GP PP PPPP R D P PG P
Sbjct: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL 289
Query: 62 -----GPPPPPHAYPFAPAAGAATSAAAEPEGP 89
GPPPP Y P P GP
Sbjct: 290 GPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGP 322
>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
Length = 1178
Score = 48.1 bits (113), Expect = 1e-05
Identities = 28/68 (41%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 28 PGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEPE 87
PGA +P R PPPPPP P P PPPPP P AG A + A P
Sbjct: 29 PGAKAPSRRRRDCRPPPPPPPPAGPSRG-----PLPPPPPPRGLGPPVAGGAAAGAGMPG 83
Query: 88 GPGASCAA 95
G G AA
Sbjct: 84 GGGGPSAA 91
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
Query: 22 GAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATS 81
G G A PGA P P PP PP+ PCAAAA G+ PA A +
Sbjct: 11 GCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGA---------CGPATAVAAA 61
Query: 82 AAAEPEGPGASCAAAAK------APVKKNAKVAGV 110
AE G G S A K AP K + GV
Sbjct: 62 GTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGV 96
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,289,090
Number of Sequences: 37866
Number of extensions: 1230092
Number of successful extensions: 32371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 694
Number of HSP's successfully gapped in prelim test: 1085
Number of HSP's that attempted gapping in prelim test: 12838
Number of HSP's gapped (non-prelim): 11618
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.