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Search of human proteins with 134031945
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134031945 SCO-spondin [Homo sapiens]
(5147 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134031945 SCO-spondin [Homo sapiens] 1.159e+04 0.0
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 625 e-178
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 606 e-172
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 602 e-171
gi|161019170 mucin 5AC [Homo sapiens] 598 e-170
gi|116284392 mucin 2 precursor [Homo sapiens] 550 e-155
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 546 e-154
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 546 e-154
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 546 e-154
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 546 e-154
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 546 e-154
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 546 e-154
gi|151301154 mucin 6, gastric [Homo sapiens] 483 e-135
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 463 e-129
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 463 e-129
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 463 e-129
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 410 e-113
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 409 e-113
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 407 e-112
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 406 e-112
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 401 e-110
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 357 2e-97
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 300 3e-80
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 286 4e-76
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 286 4e-76
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 255 9e-67
gi|134268640 tectorin alpha precursor [Homo sapiens] 210 3e-53
gi|118572606 hemicentin 1 [Homo sapiens] 208 1e-52
gi|157384998 low density lipoprotein receptor-related protein 4 ... 208 1e-52
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 199 5e-50
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 1.159e+04 bits (30089), Expect = 0.0
Identities = 5147/5147 (100%), Positives = 5147/5147 (100%)
Query: 1 MLLPALLFGMAWALADGRWCEWTETIRVEEEVAPRQEDLVPCASLDHYSRLGWRLDLPWS 60
MLLPALLFGMAWALADGRWCEWTETIRVEEEVAPRQEDLVPCASLDHYSRLGWRLDLPWS
Sbjct: 1 MLLPALLFGMAWALADGRWCEWTETIRVEEEVAPRQEDLVPCASLDHYSRLGWRLDLPWS 60
Query: 61 GRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW 120
GRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW
Sbjct: 61 GRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW 120
Query: 121 QCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGA 180
QCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGA
Sbjct: 121 QCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGA 180
Query: 181 VGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP 240
VGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP
Sbjct: 181 VGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP 240
Query: 241 QPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVR 300
QPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVR
Sbjct: 241 QPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVR 300
Query: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG
Sbjct: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
Query: 361 CLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLF 420
CLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLF
Sbjct: 361 CLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLF 420
Query: 421 AYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVS 480
AYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVS
Sbjct: 421 AYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVS 480
Query: 481 LCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDTVR 540
LCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDTVR
Sbjct: 481 LCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDTVR 540
Query: 541 QLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQ 600
QLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQ
Sbjct: 541 QLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQ 600
Query: 601 LLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASS 660
LLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASS
Sbjct: 601 LLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASS 660
Query: 661 AFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIA 720
AFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIA
Sbjct: 661 AFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIA 720
Query: 721 AFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFY 780
AFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFY
Sbjct: 721 AFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFY 780
Query: 781 LRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPAC 840
LRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPAC
Sbjct: 781 LRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPAC 840
Query: 841 GQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECN 900
GQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECN
Sbjct: 841 GQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECN 900
Query: 901 RCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPG 960
RCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPG
Sbjct: 901 RCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPG 960
Query: 961 TVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAP 1020
TVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAP
Sbjct: 961 TVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAP 1020
Query: 1021 HYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHML 1080
HYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHML
Sbjct: 1021 HYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHML 1080
Query: 1081 RGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRG 1140
RGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRG
Sbjct: 1081 RGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRG 1140
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGW 1200
RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGW
Sbjct: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGW 1200
Query: 1201 ARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHG 1260
ARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHG
Sbjct: 1201 ARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHG 1260
Query: 1261 HHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLL 1320
HHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLL
Sbjct: 1261 HHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLL 1320
Query: 1321 HGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGE 1380
HGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGE
Sbjct: 1321 HGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGE 1380
Query: 1381 ALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDD 1440
ALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDD
Sbjct: 1381 ALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDD 1440
Query: 1441 CGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCV 1500
CGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCV
Sbjct: 1441 CGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCV 1500
Query: 1501 DGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASAS 1560
DGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASAS
Sbjct: 1501 DGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASAS 1560
Query: 1561 PAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPE 1620
PAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPE
Sbjct: 1561 PAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPE 1620
Query: 1621 QLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDGQPDCG 1680
QLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDGQPDCG
Sbjct: 1621 QLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDGQPDCG 1680
Query: 1681 RPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQ 1740
RPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQ
Sbjct: 1681 RPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQ 1740
Query: 1741 ACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTK 1800
ACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTK
Sbjct: 1741 ACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTK 1800
Query: 1801 PCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEG 1860
PCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEG
Sbjct: 1801 PCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEG 1860
Query: 1861 WCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAK 1920
WCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAK
Sbjct: 1861 WCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAK 1920
Query: 1921 CLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERW 1980
CLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERW
Sbjct: 1921 CLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERW 1980
Query: 1981 HGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPA 2040
HGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPA
Sbjct: 1981 HGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPA 2040
Query: 2041 AAPAPSPQIRFPLATYILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQ 2100
AAPAPSPQIRFPLATYILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQ
Sbjct: 2041 AAPAPSPQIRFPLATYILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQ 2100
Query: 2101 GPSPQGWHAGGDAYAKWHTRPHYLQLDLLQPRNLTGILVPETGSSNAYASSFSLQFSSNG 2160
GPSPQGWHAGGDAYAKWHTRPHYLQLDLLQPRNLTGILVPETGSSNAYASSFSLQFSSNG
Sbjct: 2101 GPSPQGWHAGGDAYAKWHTRPHYLQLDLLQPRNLTGILVPETGSSNAYASSFSLQFSSNG 2160
Query: 2161 LHWHDYRDLLPGILPLPKLFPRNWDDLDPAVWTFGRMVQARFVRVWPHDVHHSDVPLQVE 2220
LHWHDYRDLLPGILPLPKLFPRNWDDLDPAVWTFGRMVQARFVRVWPHDVHHSDVPLQVE
Sbjct: 2161 LHWHDYRDLLPGILPLPKLFPRNWDDLDPAVWTFGRMVQARFVRVWPHDVHHSDVPLQVE 2220
Query: 2221 LLGCEPGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGCVLLPEGTGRFHS 2280
LLGCEPGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGCVLLPEGTGRFHS
Sbjct: 2221 LLGCEPGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGCVLLPEGTGRFHS 2280
Query: 2281 TAKTLALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESV 2340
TAKTLALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESV
Sbjct: 2281 TAKTLALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESV 2340
Query: 2341 QMVTTTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEV 2400
QMVTTTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEV
Sbjct: 2341 QMVTTTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEV 2400
Query: 2401 LGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMMPTMALPGLPAS 2460
LGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMMPTMALPGLPAS
Sbjct: 2401 LGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMMPTMALPGLPAS 2460
Query: 2461 RALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSCSRSCGLGL 2520
RALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSCSRSCGLGL
Sbjct: 2461 RALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSCSRSCGLGL 2520
Query: 2521 TFQRQELLRPPLPGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQR 2580
TFQRQELLRPPLPGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQR
Sbjct: 2521 TFQRQELLRPPLPGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQR 2580
Query: 2581 SCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCL 2640
SCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCL
Sbjct: 2581 SCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCL 2640
Query: 2641 DPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVC 2700
DPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVC
Sbjct: 2641 DPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVC 2700
Query: 2701 EKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQE 2760
EKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQE
Sbjct: 2701 EKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQE 2760
Query: 2761 LQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEE 2820
LQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEE
Sbjct: 2761 LQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEE 2820
Query: 2821 PCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQ 2880
PCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQ
Sbjct: 2821 PCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQ 2880
Query: 2881 PCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCL 2940
PCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCL
Sbjct: 2881 PCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCL 2940
Query: 2941 PRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCS 3000
PRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCS
Sbjct: 2941 PRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCS 3000
Query: 3001 CNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGY 3060
CNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGY
Sbjct: 3001 CNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGY 3060
Query: 3061 RNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH 3120
RNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH
Sbjct: 3061 RNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH 3120
Query: 3121 PGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
PGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA
Sbjct: 3121 PGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
Query: 3181 EGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAE 3240
EGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAE
Sbjct: 3181 EGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAE 3240
Query: 3241 EEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEV 3300
EEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEV
Sbjct: 3241 EEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEV 3300
Query: 3301 CQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAICV 3360
CQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAICV
Sbjct: 3301 CQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAICV 3360
Query: 3361 QPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMC 3420
QPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMC
Sbjct: 3361 QPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMC 3420
Query: 3421 SQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGP 3480
SQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGP
Sbjct: 3421 SQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGP 3480
Query: 3481 WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQ 3540
WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQ
Sbjct: 3481 WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQ 3540
Query: 3541 PCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQ 3600
PCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQ
Sbjct: 3541 PCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQ 3600
Query: 3601 SRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS 3660
SRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS
Sbjct: 3601 SRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS 3660
Query: 3661 CGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVT 3720
CGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVT
Sbjct: 3661 CGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVT 3720
Query: 3721 QQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDEL 3780
QQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDEL
Sbjct: 3721 QQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDEL 3780
Query: 3781 DSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCV 3840
DSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCV
Sbjct: 3781 DSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCV 3840
Query: 3841 LTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPA 3900
LTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPA
Sbjct: 3841 LTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPA 3900
Query: 3901 RPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSR 3960
RPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSR
Sbjct: 3901 RPAWRSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSR 3960
Query: 3961 SCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSC 4020
SCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSC
Sbjct: 3961 SCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSC 4020
Query: 4021 GGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCS 4080
GGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCS
Sbjct: 4021 GGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCS 4080
Query: 4081 DLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC 4140
DLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC
Sbjct: 4081 DLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC 4140
Query: 4141 SCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ 4200
SCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ
Sbjct: 4141 SCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ 4200
Query: 4201 SQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWS 4260
SQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWS
Sbjct: 4201 SQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWS 4260
Query: 4261 SWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCS 4320
SWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCS
Sbjct: 4261 SWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCS 4320
Query: 4321 RSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCR 4380
RSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCR
Sbjct: 4321 RSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCR 4380
Query: 4381 VLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLC 4440
VLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLC
Sbjct: 4381 VLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLC 4440
Query: 4441 ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL 4500
ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL
Sbjct: 4441 ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL 4500
Query: 4501 GCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPT 4560
GCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPT
Sbjct: 4501 GCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPT 4560
Query: 4561 GLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSL 4620
GLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSL
Sbjct: 4561 GLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSL 4620
Query: 4621 WGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCAN 4680
WGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCAN
Sbjct: 4621 WGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCAN 4680
Query: 4681 QCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQ 4740
QCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQ
Sbjct: 4681 QCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQ 4740
Query: 4741 AVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQ 4800
AVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQ
Sbjct: 4741 AVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQ 4800
Query: 4801 AQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQL 4860
AQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQL
Sbjct: 4801 AQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQL 4860
Query: 4861 LHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVD 4920
LHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVD
Sbjct: 4861 LHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVD 4920
Query: 4921 CQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVP 4980
CQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVP
Sbjct: 4921 CQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVP 4980
Query: 4981 EDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPS 5040
EDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPS
Sbjct: 4981 EDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPS 5040
Query: 5041 CRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
CRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC
Sbjct: 5041 CRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
Query: 5101 CSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQCSSCQGGDFSKR 5147
CSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQCSSCQGGDFSKR
Sbjct: 5101 CSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQCSSCQGGDFSKR 5147
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 625 bits (1611), Expect = e-178
Identities = 398/1266 (31%), Positives = 569/1266 (44%), Gaps = 132/1266 (10%)
Query: 172 ALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAV 231
AL L G + ++ + +A C+ + TFDG Y F G C+YLLAG
Sbjct: 12 ALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFS 71
Query: 232 HLTPGDRCPQPGHCQRVTMGP--EEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWL 289
+ GD V +G + L G V+ Q V + GL L+ +
Sbjct: 72 II--GDFQNGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRV--SMPYASKGLYLETEAGYY 127
Query: 290 VLSG-GLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATF 348
LSG G V R+D +G+ + + + +T GLCG +N + EDDFM G L F
Sbjct: 128 KLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDF 187
Query: 349 GNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP--FGQCH 406
NSW L E C A + C+ + G ++ + C QLL+ F +CH
Sbjct: 188 ANSWALSSGEQWCERASPPSSSCN--------ISSGEMQKGLWEQC-QLLKSTSVFARCH 238
Query: 407 AQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFC 465
V P + C C A G + C Y + CA+ + + W C
Sbjct: 239 PLVDPEPFVALCEKTLCECA-------GGLECACPALLEYARTCAQEGMVLYGWTDHSAC 291
Query: 466 ERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCP 525
+CP G Y CVS C +C+++ E C+E CV GC CP G + LCV + CP
Sbjct: 292 SPVCPAGMEYRQCVSPCARTCQSLHINE--MCQERCVDGCSCPEGQLLDEGLCVESTECP 349
Query: 526 CYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGG 585
C + +RY PG ++ + CN C+CR+ +W C+ CP EC V G H+ +FD R ++F G
Sbjct: 350 CVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGI 409
Query: 586 QGCRYSLVQDYVKGQLLILLEHGAC----DAGSCLHAISVSLEDTH---IQLRDSGAVLV 638
C+Y L +D I++E C DA C +++V L H ++L+ V +
Sbjct: 410 --CQYLLARDCQDHSFSIVIETVQCADDRDA-VCTRSVTVRLPGLHNSLVKLKHGAGVAM 466
Query: 639 NGQDVGLPWIGAE-------GLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAH 691
+GQDV LP + + SVR + L + W G L + L P +A
Sbjct: 467 DGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRL--------LVKLSPVYAG 518
Query: 692 QVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQR 751
+ GLCG + NQ DDFLTP+G E + F + +++ G C PC + +
Sbjct: 519 KTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGD--CQDLQKQHSDPCALNPRM 576
Query: 752 HAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQE 811
F+E ACA+L S F+ CHR V P+ C VC C G +CLC L++YA CA
Sbjct: 577 TRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGR 636
Query: 812 GASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGK----PEDCGELGSCVAGCNCPLGLL 867
G WR C + CP GQ Y +C C C E+C E +C+ GC CP GL
Sbjct: 637 GVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNE--ACLEGCFCPPGLY 694
Query: 868 WDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPREL 927
D G CVP + CPC + P C C++ G +CT P + P +
Sbjct: 695 MDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCED-GFMHCTMSGVPG-SLLPDAV 752
Query: 928 VYAP----GACLLTCDSPSANHSCPA------------------------GSTDGCVCPP 959
+ +P L+C P CPA G GC+CPP
Sbjct: 753 LSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPP 812
Query: 960 GTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGA 1019
G V + RCV + CPC H G+ Y P T++ CN CVCR R+W+CT C G
Sbjct: 813 GMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGM 872
Query: 1020 PHYVTFDGLAFTYPGACEYLLVRE----ASGLFTVSAQNLPCGASGLTCTKALAVRLEGT 1075
HY+TFDGL + +PG C+Y+LV++ G F + N C + C K + + +EG
Sbjct: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGG 932
Query: 1076 VVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLS 1135
+ + G V+V P + + +G +++L L+++WD + V L
Sbjct: 933 EIELFDGE------VNVKRP-MKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLK 985
Query: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDL-----PHP 1190
++ +V GLCG+FDG +NDL S +E +SW++S C + + P
Sbjct: 986 QTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPAT 1045
Query: 1191 CTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIA 1250
C N + + C L +F C+ V P+ + + C+YD C C+S GDC C C IA
Sbjct: 1046 CHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIA 1105
Query: 1251 TYADECARHGHHVRWRSQELCSLQCEGGQV----------YEACGPTCPPTCHEQHPEPG 1300
YA CA+HG V WR+ LC CE + Y +C P C TC QHPEP
Sbjct: 1106 AYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTC--QHPEP- 1162
Query: 1301 WHCQVVACVEGC--FCPEGTLLHG--GACLEPASCP-CEWGRNSFPPGSVL------QKD 1349
C V CVEGC CP G +L C++P CP CE F G + +
Sbjct: 1163 LACP-VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEH 1221
Query: 1350 CGNCTC 1355
C C C
Sbjct: 1222 CQICHC 1227
Score = 298 bits (763), Expect = 9e-80
Identities = 168/498 (33%), Positives = 231/498 (46%), Gaps = 17/498 (3%)
Query: 878 SLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAP--GACL 935
+LC C G P A ++ C + L+ T H CP + Y C
Sbjct: 253 TLCECAGGLECACP--ALLEYARTCAQEGMVLYGWTD-HSACSPVCPAGMEYRQCVSPCA 309
Query: 936 LTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNV 995
TC S N C DGC CP G +L + CV CPC HSG+ Y P ++ DCN
Sbjct: 310 RTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNT 369
Query: 996 CVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASG-LFTVSAQN 1054
C+CR QW C+ + G C +G H+ +FD FT+ G C+YLL R+ F++ +
Sbjct: 370 CICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIET 429
Query: 1055 LPCGAS-GLTCTKALAVRLEG---TVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGL 1110
+ C CT+++ VRL G ++V + G V ++G V P + G
Sbjct: 430 VQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP-LLKGDLRIQHTVTA 488
Query: 1111 FLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAEL 1170
+ LS L + WDG R+LV+LSP + G+ GLCG+++G+ +D + G+ EP E
Sbjct: 489 SVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED 548
Query: 1171 AAHSWRLSPLCPE-PGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWC 1229
++W+L C + PC +N ++ C L P F CH V P + C
Sbjct: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNC 608
Query: 1230 LYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCP 1289
YD C C G ECLC A+A+YA CA G V WR C L C GQVY CG C
Sbjct: 609 RYDVCSCSDGR--ECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCN 666
Query: 1290 PTCHEQHPEPGWHCQVVACVEGCFCPEGTLL-HGGACLEPASCPCEWGRNSFPPGSVLQK 1348
TC P C AC+EGCFCP G + G C+ A CPC + F P +
Sbjct: 667 LTCRSLS-YPDEECNE-ACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSD 724
Query: 1349 DCGNCTCQEGQWHCGGDG 1366
C C++G HC G
Sbjct: 725 HHTMCYCEDGFMHCTMSG 742
Score = 162 bits (411), Expect = 6e-39
Identities = 116/370 (31%), Positives = 159/370 (42%), Gaps = 26/370 (7%)
Query: 1007 GQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTK 1066
G+ + RC G+ TFDG +++ G C YLL A G S + +G +
Sbjct: 28 GRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLL---AGGCQKRSFSIIGDFQNGKRVS- 83
Query: 1067 ALAVRL-EGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR-RAGLFLLLSTHLGLTLLW 1124
L+V L E +H+ VT V+ P Y GL L AG + L G
Sbjct: 84 -LSVYLGEFFDIHLFVNGTVTQGDQRVSMP--YASKGLYLETEAGYYKLSGEAYGFVARI 140
Query: 1125 DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSP---LC 1181
DG V LS ++ + GLCG+F+ A +D +++G L A+SW LS C
Sbjct: 141 DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC 200
Query: 1182 PEPGDLPHPCTMNT---HRAGWARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGC 1236
C +++ + W + + LL+ +F CH V P+ C C C
Sbjct: 201 ERASPPSSSCNISSGEMQKGLWEQCQ---LLKSTSVFARCHPLVDPEPFVALCEKTLCEC 257
Query: 1237 DSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQ 1295
G EC C A+ YA CA+ G + W CS C G Y C C TC
Sbjct: 258 --AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSL 315
Query: 1296 HPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTC 1355
H CQ CV+GC CPEG LL G C+E CPC +PPG+ L +DC C C
Sbjct: 316 HINE--MCQE-RCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCIC 372
Query: 1356 QEGQWHCGGD 1365
+ QW C +
Sbjct: 373 RNSQWICSNE 382
Score = 145 bits (367), Expect = 8e-34
Identities = 124/459 (27%), Positives = 183/459 (39%), Gaps = 60/459 (13%)
Query: 560 CPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGS---CL 616
CP C H +TFDG+++ G C Y L Q+ + L ++L +GAC G+ C+
Sbjct: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGS--CSYVLFQNKEQ-DLEVILHNGACSPGARQGCM 2002
Query: 617 HAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAE-GLSVRRASSAFLLLRWPGAQVLWG 675
+I V ++L V VNG+ V +P++G ++V A + G +
Sbjct: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
Query: 676 LSDPVAYITLDPR-HAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRC 734
+ + L P+ A + GLCG +N +DF+ G V T ++ V G+
Sbjct: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Query: 735 --PSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDP 792
P + L P ++H C +L +F ECH+++ FY C C
Sbjct: 2123 CQPILEEQCLVPDSSH----------CQVLLLPLFAECHKVLAPATFYAICQQDSCH--- 2169
Query: 793 GSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC-GKPEDCG 851
+ +C V+++YA C G WR C + CP Y C C +HC G CG
Sbjct: 2170 -QEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSSCG 2228
Query: 852 ELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLG--------ARRYAPGSATMKECNRCI 903
+ S GC CP + EG CVP C +G + P + C C
Sbjct: 2229 DHPS--EGCFCPPDKVM-LEGSCVPEEACTQCIGEDGVQHQFLEAWVPDH---QPCQICT 2282
Query: 904 CQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVL 963
C NCT + CP+ A P G C + +A+ CP CVC P
Sbjct: 2283 CLSGRKVNCTTQPCPT-AKAP-----TCGLCEVARLRQNADQCCPEYE---CVCDP---- 2329
Query: 964 LDERCVPPDLCPCRHSGQWYLPNATIQEDCN---VCVCR 999
V DL P H + P T +C C CR
Sbjct: 2330 -----VSCDLPPVPHCERGLQPTLTNPGECRPNFTCACR 2363
Score = 131 bits (330), Expect = 2e-29
Identities = 164/686 (23%), Positives = 232/686 (33%), Gaps = 134/686 (19%)
Query: 996 CVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNL 1055
C CR W C C S H VTFDG F G+C Y+L + V N
Sbjct: 1940 CGCR---WTCPCV-----CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNG 1991
Query: 1056 PCGASGLT-CTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLL 1114
C C K++ V+ V + VTVNG V+ P V +++ A + +
Sbjct: 1992 ACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVR 2051
Query: 1115 STHLG-LTLLWDGGTRVLVQLSPQ-FRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA 1172
HLG + +QLSP+ F + GLCG D + +ND R G + +
Sbjct: 2052 FNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111
Query: 1173 HSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYD 1232
W + PG P + + C LL PLF CH + P Y C D
Sbjct: 2112 QEWTVQ----RPGQTCQPI-LEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQD 2166
Query: 1233 ACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTC 1292
+C E +C IA+YA C +G V WR+ + C++ C VY C CP C
Sbjct: 2167 SC------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
Query: 1293 HEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVL-----Q 1347
G H EGCFCP ++ G+C+ +C G + +
Sbjct: 2221 DGNVSSCGDHPS-----EGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDH 2275
Query: 1348 KDCGNCTCQEG-----------------------------------QWHCGGDGGHCE-E 1371
+ C CTC G ++ C D C+
Sbjct: 2276 QPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLP 2335
Query: 1372 LVPACAEG-EALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQM-TCSSGHCL 1429
VP C G + G C P+ +++C + + P C ++ T C
Sbjct: 2336 PVPHCERGLQPTLTNPGECRPNFTCACRKEEC------KRVSPPSCPPHRLPTLRKTQC- 2388
Query: 1430 PLALLCDRQDDCGDGTDEPSYPCPQGLLA--------CADGRCLPPALL----------- 1470
CD + +C + CP G LA C CLP +
Sbjct: 2389 -----CD-EYECACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQ 2442
Query: 1471 -----CDGHPDCLDAAD---------------EESCLGQVTCVPGEVSCVDGTCLGAIQL 1510
CD C D D E+SC T V E C G CL +
Sbjct: 2443 FWEEGCD-VCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECC-GRCLPS--A 2498
Query: 1511 CDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASAS------PAPP 1564
C+ V P G + +P L + + S P P
Sbjct: 2499 CEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCP 2558
Query: 1565 CGPFEFRCGSGECTPRGWRCDQEEDC 1590
G F+ C + C P RC++ E C
Sbjct: 2559 SG-FQLSCKTSACCP-SCRCERMEAC 2582
Score = 94.0 bits (232), Expect = 3e-18
Identities = 98/396 (24%), Positives = 148/396 (37%), Gaps = 77/396 (19%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP--QPGHCQRVTMGP 252
C S H TFDG+++ G C+Y+L + V L G P + G + + +
Sbjct: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQGCMKSIEVKH 2009
Query: 253 EEVLIQAGN---VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLS--GGLGVVVRLDRTGSI 307
+ ++ + V+V G+LV S+ ++G + ++ G + VR + G I
Sbjct: 2010 SALSVELHSDMEVTVNGRLV-----------SVPYVGGNMEVNVYGAIMHEVRFNHLGHI 2058
Query: 308 SISVDHE-----------LWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL-- 354
+T GLCG+ + +DFM G + T W +
Sbjct: 2059 FTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQR 2118
Query: 355 PGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEY 414
PG Q C P+ +E L ++ C LL F +CH ++PA +
Sbjct: 2119 PG------------QTCQPI------LEEQCLVPDSSH-CQVLLLPLFAECHKVLAPATF 2159
Query: 415 HEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQL 474
+ C C Q+ VC ASY C + + WR P FC CP +
Sbjct: 2160 YAICQQDSC-----------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLV 2208
Query: 475 YSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHC-PC------- 526
Y+ C CP C+ G SC + GC CP CVP C C
Sbjct: 2209 YNHCEHGCPRHCD----GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQ 2264
Query: 527 YYCRQRYVPGDTVRQLCNPCVCRDGR-WHCAQALCP 561
+ + +VP Q C C C GR +C CP
Sbjct: 2265 HQFLEAWVPD---HQPCQICTCLSGRKVNCTTQPCP 2297
Score = 90.5 bits (223), Expect = 4e-17
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 53/239 (22%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQ-PGAICVQEPCQPGCGCPGGQLL-HNGTCVPPTACPCT 4875
CP GQV C T C C L P C E C GC CP G + G CVP CPC
Sbjct: 652 CPKGQVYLQCGTPCNLTCRSLSYPDEEC-NEACLEGCFCPPGLYMDERGDCVPKAQCPCY 710
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL----------------- 4918
+ P + + + T C C G C++
Sbjct: 711 Y-------------DGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPL 757
Query: 4919 -------VDCQVPPGETWQQVAPGEL----GL-CEQTCLEMNATKTQSNCSSARASGCVC 4966
+ C+ P + V P + GL C +TC + C SGC+C
Sbjct: 758 SHRSKRSLSCRPPMVKL---VCPADNLRAEGLECTKTCQNYDLECMSMGC----VSGCLC 810
Query: 4967 QPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
PG R + CV + C C+H G+ + PG + C +C+C + CT H TC+
Sbjct: 811 PPGMVRHE-NRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCS 868
Score = 83.6 bits (205), Expect = 5e-15
Identities = 44/112 (39%), Positives = 52/112 (46%), Gaps = 17/112 (15%)
Query: 4816 PECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCT 4875
P CP G C + C C L +C QE C GC CP GQLL G CV T CPC
Sbjct: 293 PVCPAGMEYRQCVSPCARTCQSLHINEMC-QERCVDGCSCPEGQLLDEGLCVESTECPCV 351
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGE 4927
HS + PPGT L+R+C C+C + CS +C PGE
Sbjct: 352 -HS------------GKRYPPGTSLSRDCNTCICRNSQWICSNEEC---PGE 387
Score = 80.9 bits (198), Expect = 3e-14
Identities = 164/743 (22%), Positives = 242/743 (32%), Gaps = 164/743 (22%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481
SC P ++ C C C ++S C D P GC+CP + G C+P E C
Sbjct: 2202 SCPPSLVYNHCEHGCPRHCDGNVSS--CGDHP--SEGCFCPPDKVMLEGSCVPEEACTQC 2257
Query: 4482 HTSAAGAGMTLAPGDRLQLGCKECECRRG-ELHCTSQGCQGLLPLSEWSEWSPCGPCLPP 4540
L C+ C C G +++CT+Q C ++ CG C
Sbjct: 2258 IGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT-------AKAPTCGLCEVA 2310
Query: 4541 SALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPL 4600
A + E + DP +S L P+ E+ L P P P+ A
Sbjct: 2311 RLRQNADQCCPEYECVCDP--VSCDLPPVPHCERG-----LQPTLTNPGECRPNFTCACR 2363
Query: 4601 SQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCN 4660
++ P +CP +L + C+ + C G A C
Sbjct: 2364 KEECKRVSPPSCPPHRLPTLRKTQCCDEYECA----CNCVNSTVSCPLGYLASTATNDCG 2419
Query: 4661 GG-----PCPECEAQDTVFTL-----DCANQCPHSCADLWDRV------QCLQGPCRPGC 4704
P C + T++ + + + C +C D+ D V QC Q PC C
Sbjct: 2420 CTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVC--TCTDMEDAVMGLRVAQCSQKPCEDSC 2477
Query: 4705 RCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
R ++ +G C C LPSA C V S P
Sbjct: 2478 RSGFTYVLHEGEC-----CGRCLPSA------------------CEVVTGS--------P 2506
Query: 4765 VLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQ-ECNLQPCPECPPGQV 4823
S+W S G C V + +QR C P CP G
Sbjct: 2507 RGDSQSSWKSV----GSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQ 2562
Query: 4824 LSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQL-LHNGTCVPPTACPCTQHSLPWG 4882
LS C TS C P C C + + NGT + P
Sbjct: 2563 LS-CKTSACC-----------------PSCRCERMEACMLNGTVIGPGK----------- 2593
Query: 4883 LTLTLEEQAQELPPGTVLTRNCTRCVC--HGGAFSCSLVDCQVPPGETWQQVAPGELGLC 4940
TV+ CT C C G S ++C+ P LG
Sbjct: 2594 ---------------TVMIDVCTTCRCMVQVGVISGFKLECRKTTCN------PCPLGYK 2632
Query: 4941 EQTCLEMNATKTQSNCSSARASGCVCQ--PGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
E+ T C + C Q G + +D C+ H + + G
Sbjct: 2633 EEN-------NTGECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDT-HFCKVNERGEY 2684
Query: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLT 5057
W++ C P +H A+G +++ PG+CC +C + P C +T
Sbjct: 2685 FWEKRVTGC------PPFDEH---KCLAEGGKIMKIPGTCCDTC-------EEPECNDIT 2728
Query: 5058 ELRNFTK-GTCYLD-QVEVSYCSGYCPSSTHVMPEEPYLQSQCDCCS-YRLDPESPVRIL 5114
+ K G+C + +V++ YC G C S + +Q QC CCS R +P +
Sbjct: 2729 ARLQYVKVGSCKSEVEVDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRTEPMQ----V 2784
Query: 5115 NLRCLGGHTEPVVLPVIHSCQCS 5137
L C G + C+CS
Sbjct: 2785 ALHCTNGSVVYHEVLNAMECKCS 2807
Score = 79.3 bits (194), Expect = 9e-14
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPAGME C + C R C L +CQ+ C GC CP+G L +G CV C
Sbjct: 291 CSPVCPAGMEYRQCVSPCARTCQSLHINEMCQER--CVDGCSCPEGQLLDEGLCVESTEC 348
Query: 4118 DCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
C + G + PG+ CN C C+ Q C+ + CP
Sbjct: 349 PCVHS-GKRYPPGTSLSRDCNTCICRNSQWICSNEECP 385
Score = 78.6 bits (192), Expect = 2e-13
Identities = 73/284 (25%), Positives = 97/284 (34%), Gaps = 75/284 (26%)
Query: 3528 DCGGGQSLHPCGQPCPRSCQDLS-PGSVCQPGSVGCQPTCGCPLG-QLSQDGLCVPPAHC 3585
+C GQ CG PC +C+ LS P C C C CP G + + G CVP A C
Sbjct: 651 NCPKGQVYLQCGTPCNLTCRSLSYPDEECNEA---CLEGCFCPPGLYMDERGDCVPKAQC 707
Query: 3586 RCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP 3645
C Y E +P ++ + C C G + C
Sbjct: 708 PCYYDG--------------------EIFQPEDIFSDHHTMCYCEDGFMHCTM------S 741
Query: 3646 GVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRE 3705
GV S P D +S + + RPP + CPA L E
Sbjct: 742 GVPGSLLP--DAVLSSPLSHRSKRSLSCRPPMV---------------KLVCPADNLRAE 784
Query: 3706 CQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQEL 3763
G C +C + + C S GC GC CP G +H CV + CPC
Sbjct: 785 ---GLECTKTCQNYDLE--CMSMGCVSGCLCPPGMVRHENRCVALERCPC---------- 829
Query: 3764 GATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
G E G+T++ C C C K +C+ C
Sbjct: 830 ----------FHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
Score = 76.3 bits (186), Expect = 8e-13
Identities = 63/240 (26%), Positives = 83/240 (34%), Gaps = 61/240 (25%)
Query: 2963 DSCNNCTCVSGKMACT-----SERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPA 3017
D N+ SG+ C S C ++ G LW C + + R P
Sbjct: 186 DFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP 245
Query: 3018 -----------AFGGAECQGPTMEAEFCSLRPCPGPGGE---WGPWSPCSVPCGGGYRNR 3063
GG EC P + E+ R C G W S CS C G
Sbjct: 246 FVALCEKTLCECAGGLECACPAL-LEYA--RTCAQEGMVLYGWTDHSACSPVCPAG---- 298
Query: 3064 TRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGC 3123
ME+ C + PCA +C L + C GC
Sbjct: 299 --------MEYRQC-VSPCA--------------------RTCQSLHINEMCQERCVDGC 329
Query: 3124 HCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGE 3183
CP G LL +CV + +CPC H G YPPG+++ R C C C + S W C+ E
Sbjct: 330 SCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRN------SQWICSNEE 383
Score = 75.1 bits (183), Expect = 2e-12
Identities = 49/166 (29%), Positives = 67/166 (40%), Gaps = 15/166 (9%)
Query: 2822 CSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRD-CNTQ 2880
C P V P P + A C GG++ +C +L TC +
Sbjct: 237 CHPLVDPEPFV----ALCEKTLCECAGGLEC---ACPALLEYARTCAQEGMVLYGWTDHS 289
Query: 2881 PCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCL 2940
C+ CP M +R QC PC R C + C C GC+CP G L C+
Sbjct: 290 ACSPVCPAGMEYR---QCVS---PCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCV 343
Query: 2941 PRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
++CPC G+ Y G D CN C C + + C++E CP C
Sbjct: 344 ESTECPCVHSGKRYPPGTSLSRD-CNTCICRNSQWICSNEECPGEC 388
Score = 73.6 bits (179), Expect = 5e-12
Identities = 90/352 (25%), Positives = 124/352 (35%), Gaps = 80/352 (22%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLP 2941
C CP ++++ H E G CPR C G C + GC CPP + SC+P
Sbjct: 2199 CAMSCPPSLVYN-----HCEHG-CPRHC--DGNVSSCGDHPSEGCFCPPDKVMLEGSCVP 2250
Query: 2942 RSQCPCQLHGQ-----LYASGAMARLDSCNNCTCVSG-KMACTSERCPVA----CGWSPW 2991
C Q G+ + + C CTC+SG K+ CT++ CP A CG
Sbjct: 2251 EEAC-TQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCG---- 2305
Query: 2992 TLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSP 3051
LC + R R A P EC + C L P P
Sbjct: 2306 ----LCEVA-----RLRQNADQCCPE----YEC---VCDPVSCDLPPVP----------- 2338
Query: 3052 CSVPCGGGYRNRTRGSSRSLMEFS-TCGLQPCAGPVPGMCP-------RDKQWLDCAQGP 3103
C G + F+ C + C P CP R Q D +
Sbjct: 2339 ---HCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECA 2395
Query: 3104 ASC--AELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRP 3160
+C + +S P G T C C + C+P D C H +YP G
Sbjct: 2396 CNCVNSTVSCPLGYLASTATNDCGCTT------TTCLP--DKVCVHRSTIYPVGQFWEEG 2447
Query: 3161 CENCSC------VSGL-IANCSSWPCAEG-EPTWSPWTPWSQCSASCGPARC 3204
C+ C+C V GL +A CS PC + ++ +C C P+ C
Sbjct: 2448 CDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSAC 2499
Score = 72.8 bits (177), Expect = 8e-12
Identities = 53/191 (27%), Positives = 76/191 (39%), Gaps = 36/191 (18%)
Query: 2551 ACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCS 2610
+C ++ W C + +R VDP P A E+ C C+
Sbjct: 209 SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFV-------ALCEKTLC---ECA 258
Query: 2611 GGTDCELGRVYVSADLC-QKGLV-----------PPCPPS-----CLDPKA--------N 2645
GG +C + A C Q+G+V P CP C+ P A N
Sbjct: 259 GGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHIN 318
Query: 2646 RSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGEL 2705
C CV+GC CP G LL + C+ +ECPC+ + PG S L +C+ C+C +
Sbjct: 319 EMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCNTCICRNSQW 377
Query: 2706 LCQPGGCPLPC 2716
+C CP C
Sbjct: 378 ICSNEECPGEC 388
Score = 71.6 bits (174), Expect = 2e-11
Identities = 50/166 (30%), Positives = 68/166 (40%), Gaps = 16/166 (9%)
Query: 2820 EPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNT 2879
E C V P+P + + CS C G R C +LA C G +
Sbjct: 593 EACHRAVSPLPYLRN--CRYDVCS--CSDG---RECLCGALASYAAACAGRGVRVAWREP 645
Query: 2880 QPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQG-PGIECTGFCAPGCTCPPGLFL-HNA 2937
C CP+ ++ QC G PC C + P EC C GC CPPGL++
Sbjct: 646 GRCELNCPKGQVYL---QC---GTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERG 699
Query: 2938 SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCP 2983
C+P++QCPC G+++ + D C C G M CT P
Sbjct: 700 DCVPKAQCPCYYDGEIFQPEDIFS-DHHTMCYCEDGFMHCTMSGVP 744
Score = 71.2 bits (173), Expect = 2e-11
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 9/120 (7%)
Query: 2868 PGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGC 2926
P H R + +P P L A+ EG C + C Q +EC C GC
Sbjct: 756 PLSHRSKRSLSCRP-----PMVKLVCPADNLRAEGLECTKTC--QNYDLECMSMGCVSGC 808
Query: 2927 TCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
CPPG+ H C+ +CPC G+ YA G ++ CN C C K CT C C
Sbjct: 809 LCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKI-GCNTCVCRDRKWNCTDHVCDATC 867
Score = 70.9 bits (172), Expect = 3e-11
Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C E+ C SPCA C + +++CQ+ C GC CP+G L G C+ EC C H
Sbjct: 295 CPAGMEYRQCVSPCARTCQSLHINEMCQER--CVDGCSCPEGQLLDEGLCVESTECPCVH 352
Query: 4483 TSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521
+G PG L C C CR + C+++ C G
Sbjct: 353 -----SGKRYPPGTSLSRDCNTCICRNSQWICSNEECPG 386
Score = 69.3 bits (168), Expect = 9e-11
Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 9/94 (9%)
Query: 3316 GAEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLT 3372
G EY C PC R+C L C RC GC CP GQ+L +CV+ C C+ +
Sbjct: 298 GMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDE--GLCVESTECPCVH--S 353
Query: 3373 GQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
G+R+ PG L+R CN C C + C++ CP
Sbjct: 354 GKRYPPGTSLSR--DCNTCICRNSQWICSNEECP 385
Score = 68.6 bits (166), Expect = 2e-10
Identities = 157/746 (21%), Positives = 225/746 (30%), Gaps = 197/746 (26%)
Query: 4233 CQRCSCTPEGVICEDTECAVP-----------EAWTL--WSSWSDCPVSCGGGNQVRTRA 4279
C++ C G + ECA P E L W+ S C C G + R
Sbjct: 250 CEKTLCECAGGL----ECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQ-- 303
Query: 4280 CRAAAPHHRSPPCLGPDTQTRQ-----QPCPGLLEACSWGPWGPCSRSCGPGLASRSGSC 4334
C+ P +T Q + C E C G P + GL S C
Sbjct: 304 ------------CVSPCARTCQSLHINEMCQ---ERCVDGCSCPEGQLLDEGLCVESTEC 348
Query: 4335 PCLMA--------KADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCRVLVQQR 4386
PC+ + CN+ C + CP EC+ + S + R
Sbjct: 349 PCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFT--- 405
Query: 4387 YRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSH 4446
G + L +C + S + E C +C ++
Sbjct: 406 -------------------FSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVTV 446
Query: 4447 QLCQDLPPCQPGCYCPKGLLEQAGGC--------IPPEECNCWHTSAAGAGMTLAPGDRL 4498
+L PG + L+ G +P + + A + L+ G+ L
Sbjct: 447 RL--------PGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDL 498
Query: 4499 QLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPC-----------LPPSALAPAS 4547
Q+ RG L L+ LS CG C L PS LA
Sbjct: 499 QMDWDG----RGRL---------LVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPR 545
Query: 4548 RTALEEHWL------------RDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHL 4595
W DP L+P + + C P A H
Sbjct: 546 VEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT------RFSEEACA--VLTSPTFEACHR 597
Query: 4596 CTAPLSQQRLCP-DPGACPDSCQWSLWGPWSPCQVPCSG-GFRLRWREAEALCGGGCREP 4653
+PL R C D +C D + L G + C+G G R+ WRE G C
Sbjct: 598 AVSPLPYLRNCRYDVCSCSDGRE-CLCGALASYAAACAGRGVRVAWREP-----GRCELN 651
Query: 4654 WAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQ 4713
CP+ + L C C +C L + C GC CPPG +
Sbjct: 652 ----------CPKGQVY-----LQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMD 696
Query: 4714 D-GRCVPISSCRCGLPSANASWELAPAQAVQLDCQN-CTCVNESLVCPHQECPVLGPWSA 4771
+ G CVP + C C E+ + + D C C + + C P G
Sbjct: 697 ERGDCVPKAQCPCYYDG-----EIFQPEDIFSDHHTMCYCEDGFMHCTMSGVP--GSLLP 749
Query: 4772 WSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSC 4831
+ S+P HR+ ++ C P L A C
Sbjct: 750 DAVLSSPLS------HRS---------------KRSLSCRPPMVKLVCPADNLRAEGLEC 788
Query: 4832 PCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQA 4891
C + C+ C GC CP G + H CV CPC Q
Sbjct: 789 TKTCQNYD--LECMSMGCVSGCLCPPGMVRHENRCVALERCPCF-------------HQG 833
Query: 4892 QELPPGTVLTRNCTRCVCHGGAFSCS 4917
+E PG + C CVC ++C+
Sbjct: 834 KEYAPGETVKIGCNTCVCRDRKWNCT 859
Score = 67.4 bits (163), Expect = 4e-10
Identities = 128/548 (23%), Positives = 177/548 (32%), Gaps = 166/548 (30%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CP + C + CPR C +G V +GC CP + +G CVP C
Sbjct: 2199 CAMSCPPSLVYNHCEHGCPRHC----DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEAC 2254
Query: 4118 -DCTDAQG------HSWAPGSQHQDACNNCSCQAG-QLSCTAQPCP---PPT-------- 4158
C G +W P Q C C+C +G +++CT QPCP PT
Sbjct: 2255 TQCIGEDGVQHQFLEAWVPDHQ---PCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVAR 2311
Query: 4159 ------HCAWSHWSAWSPCSHSCGP-----RGQQSRFRSSTSGSWAPE----CREEQSQS 4203
C + P S P RG Q + G P CR+E+ +
Sbjct: 2312 LRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTL--TNPGECRPNFTCACRKEECKR 2369
Query: 4204 QPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWS 4263
PSCPP L R D + EC C+C V C P + ++ +
Sbjct: 2370 --VSPPSCPPHRLPTLRKTQCCDEY---EC-ACNCVNSTVSC-------PLGYLASTATN 2416
Query: 4264 DCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSC 4323
DC C + + C HRS + P Q ++ C + C+ C+
Sbjct: 2417 DC--GCTTTTCLPDKVC-----VHRS--TIYPVGQFWEEGC----DVCT------CTDME 2457
Query: 4324 GPGLASRSGSC---PCLMAKADPTCNSTFLHLDTQGCYSGPC-PEECV-------WSSWS 4372
+ R C PC + +C S F ++ +G G C P C S S
Sbjct: 2458 DAVMGLRVAQCSQKPC-----EDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQS 2512
Query: 4373 SWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNC----------SEDS 4422
SW S G++ +P PCLI+ C +
Sbjct: 2513 SW------------------KSVGSQWASP-------ENPCLINECVRVKEEVFIQQRNV 2547
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
P E C S QL C P C C E+ C+
Sbjct: 2548 SCPQLEVPVCPS----------GFQLSCKTSACCPSCRC-----ERMEACML-------- 2584
Query: 4483 TSAAGAGMTLAPGDRLQLG-CKECEC-------RRGELHCTSQGCQGLLPL---SEWSEW 4531
G + PG + + C C C +L C C PL E +
Sbjct: 2585 -----NGTVIGPGKTVMIDVCTTCRCMVQVGVISGFKLECRKTTCNP-CPLGYKEENNTG 2638
Query: 4532 SPCGPCLP 4539
CG CLP
Sbjct: 2639 ECCGRCLP 2646
Score = 66.6 bits (161), Expect = 6e-10
Identities = 41/128 (32%), Positives = 57/128 (44%), Gaps = 13/128 (10%)
Query: 1784 RTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVTCPPDWP 1842
RTCA L+ C + C + ++ C +PC TC + C
Sbjct: 273 RTCAQEGMVLYGWTDHSAC------SPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCV 326
Query: 1843 CGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRL 1902
GC CPEGQ+L EG CV +CPC+ G RY PG + DC CIC++ +
Sbjct: 327 ---DGCSCPEGQLL-DEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNS--QWICS 380
Query: 1903 NPDCAVDC 1910
N +C +C
Sbjct: 381 NEECPGEC 388
Score = 63.5 bits (153), Expect = 5e-09
Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 1272 SLQCEGGQVYEAC--------GPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGG 1323
SL C V C G C TC E C + CV GC CP G + H
Sbjct: 764 SLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLE----CMSMGCVSGCLCPPGMVRHEN 819
Query: 1324 ACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C+ CPC + PG ++ C C C++ +W+C
Sbjct: 820 RCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNC 858
Score = 62.8 bits (151), Expect = 9e-09
Identities = 53/186 (28%), Positives = 70/186 (37%), Gaps = 15/186 (8%)
Query: 3996 CNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNP 4055
C+ P+P + R + C SC G R C + A CAG + P
Sbjct: 595 CHRAVSPLP--YLRNCRYDVC--SCSDG-----RECLCGALASYAAACAGRGVRVAWREP 645
Query: 4056 MPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKG-SLEQDGGCVPI 4114
CE CP G + C C C L + ++ C +GC CP G +++ G CVP
Sbjct: 646 GRCELNCPKGQVYLQCGTPCNLTCRSLSYPDE-ECNEACLEGCFCPPGLYMDERGDCVPK 704
Query: 4115 GHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPP---PTHCAWSHWSAWSPC 4171
C C G + P D C C+ G + CT P P S S S
Sbjct: 705 AQCPCY-YDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKR 763
Query: 4172 SHSCGP 4177
S SC P
Sbjct: 764 SLSCRP 769
Score = 62.4 bits (150), Expect = 1e-08
Identities = 84/357 (23%), Positives = 119/357 (33%), Gaps = 81/357 (22%)
Query: 4213 PLCLQGTRSRTLGDSW-LQGECQR--------CSCTPEGVICEDTECAV---PEAWTLWS 4260
P L R G++W L G+CQ C+ P + CAV P
Sbjct: 538 PSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHR 597
Query: 4261 SWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCS 4320
+ S P R C + CL + C G +W G C
Sbjct: 598 AVSPLPYL----RNCRYDVCSCSDGRE----CLCGALASYAAACAGRGVRVAWREPGRCE 649
Query: 4321 RSCGPGLASRSGSCPC-----LMAKADPTCNSTFLHLDTQGCYSGP-------------- 4361
+C G PC ++ D CN L +GC+ P
Sbjct: 650 LNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACL----EGCFCPPGLYMDERGDCVPKA 705
Query: 4362 -CP---------EECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFR 4411
CP E ++S T C C + + H +G P + L
Sbjct: 706 QCPCYYDGEIFQPEDIFSDHH--TMCYC----EDGFMHC------TMSGVPGSLLPDAVL 753
Query: 4412 PCLISNCSEDS--CTPPFEFHACGSPCAGLCATHLS-HQLCQDLP------PCQPGCYCP 4462
+S+ S+ S C PP C P L A L + CQ+ C GC CP
Sbjct: 754 SSPLSHRSKRSLSCRPPMVKLVC--PADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCP 811
Query: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGC 4519
G++ C+ E C C+H G APG+ +++GC C CR + +CT C
Sbjct: 812 PGMVRHENRCVALERCPCFH-----QGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
Score = 61.2 bits (147), Expect = 3e-08
Identities = 42/160 (26%), Positives = 57/160 (35%), Gaps = 24/160 (15%)
Query: 3484 CDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCP 3543
C+ L + C+ P E R C ++S C G C PC
Sbjct: 250 CEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCA 309
Query: 3544 RSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRS 3603
R+CQ L +CQ C C CP GQL +GLCV C C +
Sbjct: 310 RTCQSLHINEMCQER---CVDGCSCPEGQLLDEGLCVESTECPCVH-------------- 352
Query: 3604 AGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
+G R+ PG ++ C+ C C C +CP
Sbjct: 353 SGKRY------PPGTSLSRDCNTCICRNSQWICSN-EECP 385
Score = 60.8 bits (146), Expect = 3e-08
Identities = 57/214 (26%), Positives = 80/214 (37%), Gaps = 51/214 (23%)
Query: 3609 SSWESLEPGEVVTGPCDNCTCVAG---ILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGE 3665
SS ++ GE+ G + C + +C + D P+P V E C GG
Sbjct: 207 SSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVD-PEPFV----ALCEKTLCECAGGL 261
Query: 3666 QLRSRRCARPPCPGPARQSRTCSTQVCREAG----------CPAGRLYRECQPGEGCPFS 3715
+ CA CP +RTC+ + G CPAG YR+C C +
Sbjct: 262 E-----CA---CPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCV--SPCART 311
Query: 3716 CAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQP 3773
C + C E C +GC CPEG CV+ ECPCV +
Sbjct: 312 CQSLHINEMC-QERCVDGCSCPEGQLLDEGLCVESTECPCVHS----------------- 353
Query: 3774 LGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
G G +L C C C + + CS ++C
Sbjct: 354 ---GKRYPPGTSLSRDCNTCICRNSQWICSNEEC 384
Score = 60.1 bits (144), Expect = 6e-08
Identities = 103/474 (21%), Positives = 145/474 (30%), Gaps = 127/474 (26%)
Query: 4680 NQCPHSCADLWDR--VQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
N C H C D C P GC CPP +++ +G CVP +C + +
Sbjct: 2210 NHCEHGCPRHCDGNVSSCGDHPSE-GCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFL 2268
Query: 4738 PAQAV-QLDCQNCTCVNESLV-CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPG 4795
A CQ CTC++ V C Q CP + AP G E R +
Sbjct: 2269 EAWVPDHQPCQICTCLSGRKVNCTTQPCP---------TAKAPT-CGLCEVARLRQNADQ 2318
Query: 4796 VAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
P + + C+L P P C G LQP
Sbjct: 2319 CCP-EYECVCDPVSCDLPPVPHCERG----------------LQP--------------- 2346
Query: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFS 4915
L + G C P C C + PP + T T+C
Sbjct: 2347 ---TLTNPGECRPNFTCACRKEECK-------RVSPPSCPPHRLPTLRKTQC-------- 2388
Query: 4916 CSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQA 4975
C +C C+ + +S + C C
Sbjct: 2389 CDEYECAC-------------------NCVNSTVSCPLGYLASTATNDCGC-------TT 2422
Query: 4976 GPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPV--------CTQHCSPLTCAQG 5027
C+P+ C H + G W+E C+ C C C+Q +C G
Sbjct: 2423 TTCLPDK--VCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSG 2480
Query: 5028 EEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHV 5087
VL G CC C A C+++T +G S S S
Sbjct: 2481 FTYVLHEGECCGRCLPSA-------CEVVT---GSPRGD--------SQSSWKSVGSQWA 2522
Query: 5088 MPEEPYLQSQCDCCSYRLDPESPVRILNLRCLGGHTEPVVLP--VIHSCQCSSC 5139
PE P L ++C R+ E ++ N+ C E V P SC+ S+C
Sbjct: 2523 SPENPCLINEC----VRVKEEVFIQQRNVSC--PQLEVPVCPSGFQLSCKTSAC 2570
Score = 59.3 bits (142), Expect = 1e-07
Identities = 104/433 (24%), Positives = 137/433 (31%), Gaps = 98/433 (22%)
Query: 3319 YSPCGPPCPRSCDDLVH-CVWRCQPGCYCPPGQVLSSNGAICVQPGHCS-CLDLLTGQRH 3376
Y+ C CPR CD V C GC+CPP +V+ CV C+ C+ Q
Sbjct: 2209 YNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGS--CVPEEACTQCIGEDGVQHQ 2266
Query: 3377 HPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPG----GWCPWSEWTMCSQPCRGQTRSR 3431
A + C CTCL GR +NCT PCP G C + + C +
Sbjct: 2267 FLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECV 2326
Query: 3432 SRACACPTP-----QHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDM 3486
+C P + G P GE C TC
Sbjct: 2327 CDPVSCDLPPVPHCERGLQPTLTNPGE---------CRPNFTC----------------- 2360
Query: 3487 CLGQSHRSRACSRPPTPEGGRPCPGNH----TQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
+ R C R P CP + +++ C E C +C P G
Sbjct: 2361 ----ACRKEECKRVSPPS----CPPHRLPTLRKTQCCDEYECAC-NCVNSTVSCPLGYLA 2411
Query: 3543 PRSCQDLS-PGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-QYQPGAMGIPENQ 3600
+ D + C P V + P+GQ ++G V C C + MG+ Q
Sbjct: 2412 STATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDV----CTCTDMEDAVMGLRVAQ 2467
Query: 3601 SRSA----GSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSW----G 3652
R L GE C C A C+ V P SSW
Sbjct: 2468 CSQKPCEDSCRSGFTYVLHEGEC----CGRCLPSA----CEVVTGSPRGDSQSSWKSVGS 2519
Query: 3653 PWEDCSVSCGGGE----------QLRSRRCAR---PPCPGPARQSRTCSTQVCREAGCPA 3699
W C E Q R+ C + P CP + S C T C CP+
Sbjct: 2520 QWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLS--CKTSAC----CPS 2573
Query: 3700 GRLYRECQPGEGC 3712
R C+ E C
Sbjct: 2574 CR----CERMEAC 2582
Score = 58.9 bits (141), Expect = 1e-07
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 2652 CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGG 2711
CV GC CPPG++ H+ RC+ L CPC + PG + +G C+ CVC + C
Sbjct: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG-CNTCVCRDRKWNCTDHV 862
Query: 2712 CPLPC 2716
C C
Sbjct: 863 CDATC 867
Score = 57.8 bits (138), Expect = 3e-07
Identities = 72/292 (24%), Positives = 100/292 (34%), Gaps = 41/292 (14%)
Query: 2570 SCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQK 2629
SC G R C+ + A C G A +P +C G+VY+
Sbjct: 614 SCSDG-----RECLCGALASYAAACAGRGVRVA--WREPGRCELNCPKGQVYLQCGT--- 663
Query: 2630 GLVPPCPPSCLDPK-ANRSCSGHCVEGCRCPPGLLLHDT-RCLPLSECPCLVGEELKWPG 2687
PC +C + C+ C+EGC CPPGL + + C+P ++CPC E+ P
Sbjct: 664 ----PCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPE 719
Query: 2688 VSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPA 2747
F + + C CE G + C G P S S R++ PP
Sbjct: 720 DIF-SDHHTMCYCEDGFMHCTMSGVP-------GSLLPDAVLSSPLSHRSKRSLSCRPPM 771
Query: 2748 AWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRS---RLC 2804
P + R E C C + C CL P G +R C
Sbjct: 772 VKLVCPADNLRAEGLECTKTCQ----NYDLECMSMGCVSGCLCPPGMVRHENRCVALERC 827
Query: 2805 P--SPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRG 2854
P G PG+ T + C+ VC W+ CD T G
Sbjct: 828 PCFHQGKEYAPGE-TVKIGCNTCVCRD-------RKWNCTDHVCDATCSTIG 871
Score = 57.8 bits (138), Expect = 3e-07
Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 29/165 (17%)
Query: 4650 CREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPG 4709
CR P + C P A+ L+C C + +D ++C+ C GC CPPG
Sbjct: 767 CRPPMVKLVC---PADNLRAEG----LECTKTCQN-----YD-LECMSMGCVSGCLCPPG 813
Query: 4710 QLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPW 4769
+ + RCV + C C + E AP + V++ C C C + C
Sbjct: 814 MVRHENRCVALERCPC----FHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH-------- 861
Query: 4770 SAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQP 4814
C A C M + T +G + P + Q + C P
Sbjct: 862 ----VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNP 902
Score = 57.4 bits (137), Expect = 4e-07
Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 12/92 (13%)
Query: 1807 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSP---GCWCPEGQVLGSEGWCV 1863
CP G++ Q PC LTC +S PD C GC+CP G + G CV
Sbjct: 652 CPK----GQVYLQCGTPCNLTCRSLSY-----PDEECNEACLEGCFCPPGLYMDERGDCV 702
Query: 1864 WPRQCPCLVDGARYWPGQRIKADCQLCICQDG 1895
QCPC DG + P +C C+DG
Sbjct: 703 PKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDG 734
Score = 56.6 bits (135), Expect = 6e-07
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 3089 MCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
+CP D + + +C + C GC CP GM+ N CV + CPC H+G
Sbjct: 775 VCPADNLRAEGLECTKTCQNYDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQG 833
Query: 3149 HLYPPGSTVVRPCENCSC 3166
Y PG TV C C C
Sbjct: 834 KEYAPGETVKIGCNTCVC 851
Score = 56.2 bits (134), Expect = 8e-07
Identities = 71/276 (25%), Positives = 92/276 (33%), Gaps = 73/276 (26%)
Query: 3901 RPAWRSRTRLCLANCTMGDPLQE--RPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPC 3958
R AWR R C NC G + PCNL +C L P E C
Sbjct: 639 RVAWREPGR-CELNCPKGQVYLQCGTPCNL-TCRSLSY-----------------PDEEC 679
Query: 3959 SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRA-CPVPGGWSRWSP----- 4012
+ +C G + PPG ER C +A CP + P
Sbjct: 680 NEACLEG------CFCPPG----------LYMDERGDCVPKAQCPCYYDGEIFQPEDIFS 723
Query: 4013 -----------WSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAG 4061
+ C S G L SSP S ++ C P +
Sbjct: 724 DHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRS--------KRSLSCRPPMVKLV 775
Query: 4062 CPAG---MEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCD 4118
CPA E + C C DL+ C C GC CP G + + CV + C
Sbjct: 776 CPADNLRAEGLECTKTCQNY--DLE----CMS-MGCVSGCLCPPGMVRHENRCVALERCP 828
Query: 4119 CTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
C QG +APG + CN C C+ + +CT C
Sbjct: 829 CFH-QGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863
Score = 55.8 bits (133), Expect = 1e-06
Identities = 38/104 (36%), Positives = 45/104 (43%), Gaps = 16/104 (15%)
Query: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCD--DLVHCVWRCQPGCYCPPGQVLSSNGAICVQ 3361
L CP N A EG E C ++C DL C GC CPPG V N CV
Sbjct: 774 LVCPADNLRA-EGLE-------CTKTCQNYDLECMSMGCVSGCLCPPGMVRHENR--CVA 823
Query: 3362 PGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
C C G+ + PG + GCN C C + + NCTD C
Sbjct: 824 LERCPCFH--QGKEYAPGETVKI--GCNTCVCRDRKWNCTDHVC 863
Score = 53.5 bits (127), Expect = 5e-06
Identities = 49/174 (28%), Positives = 67/174 (38%), Gaps = 26/174 (14%)
Query: 3310 NCTAIEGAEYSPCGPPCPRSCDDLVH----CVWRCQPGCYCPPGQVLSSNGAICVQPGHC 3365
NC +G Y CG PC +C L + C C GC+CPPG + G CV C
Sbjct: 651 NCP--KGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGD-CVPKAQC 707
Query: 3366 SCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCR 3425
C G+ P + D C C +G ++CT VPG P + + S P
Sbjct: 708 PC--YYDGEIFQPEDIFS--DHHTMCYCEDGFMHCT--MSGVPGSLLPDA---VLSSPLS 758
Query: 3426 GQTRSRSRAC-------ACPTP--QHGGAPCTGEAGEAGAQHQREACPSYATCP 3470
+++ RS +C CP + G CT + C S CP
Sbjct: 759 HRSK-RSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCP 811
Score = 52.0 bits (123), Expect = 2e-05
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 4924 PPGETWQQ-VAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPED 4982
P G ++Q V+P C +TC ++ + C GC C G + G CV
Sbjct: 296 PAGMEYRQCVSP-----CARTCQSLHINEM---CQERCVDGCSCPEGQLLDE-GLCVEST 346
Query: 4983 HCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
C C H G+ + PG+ C +C+C + + +C+ P C
Sbjct: 347 ECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGEC 388
Score = 51.6 bits (122), Expect = 2e-05
Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 11/100 (11%)
Query: 3319 YSPCGPPCPRSCD--DLVHCVWRCQPGCY--CPPGQVLSSNGAICVQPGHCSCLDLLTGQ 3374
Y+ C P C +C + + C +C GC+ CPPG++L CV P C + + G+
Sbjct: 1146 YNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE-VAGR 1204
Query: 3375 RHHPGARL----ARPDGCNHCTCLEGRLNCTDLPCPVPGG 3410
R G ++ + P+ C C C L C C PGG
Sbjct: 1205 RFASGKKVTLNPSDPEHCQICHCDVVNLTCE--ACQEPGG 1242
Score = 50.8 bits (120), Expect = 3e-05
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 3090 CPRDKQWLDCAQG-PASCAELSAP-RGTNQTCHPGCHCPSGMLL-LNNVCVPTQDCPCAH 3146
CP+ + +L C +C LS P N+ C GC CP G+ + CVP CPC +
Sbjct: 652 CPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYY 711
Query: 3147 EGHLYPPGSTVVRPCENCSCVSGLI 3171
+G ++ P C C G +
Sbjct: 712 DGEIFQPEDIFSDHHTMCYCEDGFM 736
Score = 48.9 bits (115), Expect = 1e-04
Identities = 42/142 (29%), Positives = 57/142 (40%), Gaps = 19/142 (13%)
Query: 1772 RQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPN---ATCSGELMFQPCAP-CPLT 1827
+Q CH Q C + H R C P+ +C L++ C CP
Sbjct: 2164 QQDSCHQEQ----VCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
Query: 1828 CDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLV--DGARYWPGQRIKA 1885
CD G V+ D P S GC+CP +V+ EG CV C + DG ++ +
Sbjct: 2220 CD---GNVSSCGDHP--SEGCFCPPDKVM-LEGSCVPEEACTQCIGEDGVQHQFLEAWVP 2273
Query: 1886 D---CQLCICQDGRPRRCRLNP 1904
D CQ+C C GR C P
Sbjct: 2274 DHQPCQICTCLSGRKVNCTTQP 2295
Score = 46.2 bits (108), Expect = 8e-04
Identities = 123/546 (22%), Positives = 165/546 (30%), Gaps = 120/546 (21%)
Query: 1299 PGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEG 1358
PG CQ + E C P+ + H L P C VL CQ+
Sbjct: 2119 PGQTCQPIL-EEQCLVPDSS--HCQVLLLPLFAECH---------KVLAPATFYAICQQ- 2165
Query: 1359 QWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGE 1418
D H E++ A LC+ NG CV D + CA C
Sbjct: 2166 ------DSCHQEQVCEVIASYAHLCRTNGVCV-------------DWRTPDFCAM-SCPP 2205
Query: 1419 GQMTCSSGHCLPLALLCD-RQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDC 1477
+ H P CD CGD E + P ++ +G C+P C
Sbjct: 2206 SLVYNHCEHGCPRH--CDGNVSSCGDHPSEGCFCPPDKVM--LEGSCVP-------EEAC 2254
Query: 1478 LDAADEESCLGQV--TCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPT 1535
E+ Q VP C TCL ++ CP G C + L
Sbjct: 2255 TQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQ 2314
Query: 1536 PPASTLPGPSPGSLDTASSPLA-SASPAPPC--GPFEFRCGSGECTPRGWRCDQEEDCAD 1592
P + P++ P P C G GEC P ++E+C
Sbjct: 2315 NADQCCP-----EYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEEC-- 2367
Query: 1593 GSDERGCGGPCAPHHAPCARGPHCVSP-EQLCDGVR---QCPDG--SDEGPDACGGLPAL 1646
+R C PH P R C E C+ V CP G + + CG
Sbjct: 2368 ---KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCTTTT 2424
Query: 1647 GGPNR------TGLPCPEY---TCPNGTCIGFQLVCDGQPDCGRPGQVGPSPEEQGCGAW 1697
P++ T P ++ C TC + G R Q P E C +
Sbjct: 2425 CLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGL----RVAQCSQKPCEDSCRSG 2480
Query: 1698 GPW-SPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEW-ST 1755
+ G C CG RC P V+ P + QS W S
Sbjct: 2481 FTYVLHEGEC---CG--------RCLPSACEVVTGSPRGDSQS------------SWKSV 2517
Query: 1756 WSPWSVCSEPC---------RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDG 1806
S W+ PC +QR PQ C P G + +T C
Sbjct: 2518 GSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVC---PSGFQLSCKTSAC---- 2570
Query: 1807 CPNATC 1812
CP+ C
Sbjct: 2571 CPSCRC 2576
Score = 45.4 bits (106), Expect = 0.001
Identities = 98/415 (23%), Positives = 129/415 (31%), Gaps = 82/415 (19%)
Query: 3538 CGQPCPRSCQDLSPGSVCQPGSVGCQPT--CGCPLGQLSQDGLCVPPAHCRCQYQPGAMG 3595
C CPR C G+V S G P+ C CP ++ +G CVP C
Sbjct: 2212 CEHGCPRHCD----GNV---SSCGDHPSEGCFCPPDKVMLEGSCVPEEAC---------- 2254
Query: 3596 IPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAG-ILQCQEVPDCPDPGVWSSWGPW 3654
++ G + LE PC CTC++G + C P CP
Sbjct: 2255 -----TQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQP-CPTAK-------- 2300
Query: 3655 EDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCP- 3713
+ +CG E R R+ A CP S + C G PGE P
Sbjct: 2301 ---APTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPN 2357
Query: 3714 FSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRL------ACVQECPCVLTAWLLQELGATI 3767
F+CA C E C+ P HRL C E C + +T+
Sbjct: 2358 FTCA-------CRKEECKR--VSPPSCPPHRLPTLRKTQCCDEYECACNC-----VNSTV 2403
Query: 3768 GDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPCSRSC 3827
P L D G T T + C H + +E G +C
Sbjct: 2404 SCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEE----------GCDVCTC 2453
Query: 3828 GGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEPVTGLPGGWGPWS 3887
+ + CR + C S E VTG P G S
Sbjct: 2454 TDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRG-DSQS 2512
Query: 3888 SWSPCSRSCTDPARPAWRSRTRLCLAN-CTMGDP---LQERPCNLPSCTELPVCP 3938
SW P P CL N C +Q+R + P E+PVCP
Sbjct: 2513 SWKSVGSQWASPENP--------CLINECVRVKEEVFIQQRNVSCPQ-LEVPVCP 2558
Score = 44.7 bits (104), Expect = 0.002
Identities = 82/331 (24%), Positives = 104/331 (31%), Gaps = 77/331 (23%)
Query: 3420 CSQPCRGQTRS----RSRACACPTPQ---HGGA----PCTGEAGEAGAQHQREACPSYAT 3468
C + C G S S C CP + G CT GE G QHQ
Sbjct: 2216 CPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLE------ 2269
Query: 3469 CPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTD 3528
AW P PC +C S R C+ P P P G +R ++N+ QC
Sbjct: 2270 -----AWVP--DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVAR-LRQNADQC-- 2319
Query: 3529 CGGGQSLHPCGQPCPR-SCQDLSPGSVCQPGSVGCQPTCGCPLG---QLSQDGLCVPPAH 3584
CP C VC P S P C G L+ G C P
Sbjct: 2320 -------------CPEYEC-------VCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFT 2359
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCT--CVAGILQCQEVPDC 3642
C C+ + P + + + E C N T C G L DC
Sbjct: 2360 CACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACN-CVNSTVSCPLGYLASTATNDC 2418
Query: 3643 --------PD------PGVWSSWGPWED-CSV-SCGGGEQ----LRSRRCARPPCPGPAR 3682
PD ++ WE+ C V +C E LR +C++ PC R
Sbjct: 2419 GCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCR 2478
Query: 3683 QSRTCSTQVCREAGCPAGRLYRECQPGEGCP 3713
T V E C L C+ G P
Sbjct: 2479 SG---FTYVLHEGECCGRCLPSACEVVTGSP 2506
Score = 40.8 bits (94), Expect = 0.035
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 20/109 (18%)
Query: 4825 SACATSCPCLCWHLQPGAICVQEPCQPGC--GCPGGQLLHN--GTCVPPTACPCTQ---H 4877
++CA +C C H +P A VQ C GC CP G++L TCV P CP +
Sbjct: 1147 NSCAPACQVTCQHPEPLACPVQ--CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGR 1204
Query: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPG 4926
G +TL E +C C C +C CQ P G
Sbjct: 1205 RFASGKKVTLNPSDPE---------HCQICHCDVVNLTCEA--CQEPGG 1242
Score = 40.0 bits (92), Expect = 0.060
Identities = 29/99 (29%), Positives = 38/99 (38%), Gaps = 24/99 (24%)
Query: 2635 CPPSCLDPKANRSCSGHC-----------VEGCRCPPGLLLHDTRCLPLSECPCLVGEEL 2683
CPPS + C HC EGC CPP ++ + C+P C +GE+
Sbjct: 2203 CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGED- 2261
Query: 2684 KWPGV--SFLLG------NCSQCVCEKG-ELLCQPGGCP 2713
GV FL C C C G ++ C CP
Sbjct: 2262 ---GVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCP 2297
Score = 38.1 bits (87), Expect = 0.23
Identities = 100/416 (24%), Positives = 128/416 (30%), Gaps = 83/416 (19%)
Query: 2543 RSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSR---QRSCVDPPPKNGGAPCPGASQ 2599
R +C Q CP A A G C V+ + + + CV P P P +
Sbjct: 2287 RKVNCTTQPCPTAKA----PTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCER 2342
Query: 2600 ERAPCGLQP--CSGGTDCELGRVYVSADLCQKGLVPPCPP---------SCLDPKANRSC 2648
P P C C + + C++ P CPP C D C
Sbjct: 2343 GLQPTLTNPGECRPNFTCACRK-----EECKRVSPPSCPPHRLPTLRKTQCCD---EYEC 2394
Query: 2649 SGHCVEG-CRCPPGLLLH---------DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQC 2698
+ +CV CP G L T CLP C V +P F C C
Sbjct: 2395 ACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVC---VHRSTIYPVGQFWEEGCDVC 2451
Query: 2699 VCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDR 2758
C E G + A S PC+ SC SG G C R
Sbjct: 2452 TCTDMEDAVM--GLRV-----AQCSQKPCEDSCRSGFTYVLHE---------GECC--GR 2493
Query: 2759 QELQGCHTVCGT-EVFGWTPWTS----WSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCP 2813
C V G+ + W S W+S CL R + + + SCP
Sbjct: 2494 CLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLI---NECVRVKEEVFIQQRNVSCP 2550
Query: 2814 GDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQ 2873
PVC PS + L S C C R +C + G PG
Sbjct: 2551 -------QLEVPVC--PSGFQLSCKTSACCPSCR---CERMEAC--MLNGTVIGPGKTVM 2596
Query: 2874 TRDCNTQPCTAQCPENMLFRSAEQCHQEG-GPCPRLCLTQGPGIECTGFCAP-GCT 2927
C T C Q F+ +C + PCP + EC G C P CT
Sbjct: 2597 IDVCTTCRCMVQVGVISGFKL--ECRKTTCNPCPLGYKEENNTGECCGRCLPTACT 2650
Score = 37.0 bits (84), Expect = 0.51
Identities = 40/167 (23%), Positives = 56/167 (33%), Gaps = 59/167 (35%)
Query: 1741 ACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTK 1800
A + C G+ TW ++C + C R+ G C
Sbjct: 1105 AAYAHVCAQHGKVVTWRTATLCPQSCEERNLRE--------NGYEC-------------- 1142
Query: 1801 PCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSP-----GC--WCPEG 1853
E + CAP + QVTC P P GC CP G
Sbjct: 1143 --------------EWRYNSCAP--------ACQVTCQHPEPLACPVQCVEGCHAHCPPG 1180
Query: 1854 QVLGS-EGWCVWPRQCP-CLVDGARYWPGQRIKAD------CQLCIC 1892
++L CV P CP C V G R+ G+++ + CQ+C C
Sbjct: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
Score = 37.0 bits (84), Expect = 0.51
Identities = 109/500 (21%), Positives = 144/500 (28%), Gaps = 115/500 (23%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
CP +Y C+ GCP H V + EGC CP +CV E C
Sbjct: 2203 CPPSLVYNHCE--HGCP---RHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACT-- 2255
Query: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHG-KLSCSLDDCFEADGGFG 3815
IG+ G L++ C C+C G K++C+ C A
Sbjct: 2256 --------QCIGEDGV---QHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAK---- 2300
Query: 3816 PWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEP 3875
P C R + QC P + C C + P
Sbjct: 2301 -----APTCGLCEVARLRQNADQCC-------------PEYECVCDPVSC------DLPP 2336
Query: 3876 VTGLPGGWGPWSSWSPCSRSCTDP--ARPAWRSRTRLCLANCTMGDPLQERPCNLPSCTE 3933
V G P + T+P RP + R C P P LP+ +
Sbjct: 2337 VPHCERGLQP---------TLTNPGECRPNFTCACR--KEECKRVSPPSCPPHRLPTLRK 2385
Query: 3934 LPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
C C A NC + SC +G + C T
Sbjct: 2386 TQCCDEYEC-ACNC--------VNSTVSCPLGYL--------ASTATNDCGCTTTTCLPD 2428
Query: 3994 RFCNLRACPVPGG--WSRWSPWSWCDRSCGGGQSLRSRSCSSPP----SKNGGAPCAGER 4047
+ C R+ P G W C LR CS P ++G E
Sbjct: 2429 KVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEG 2488
Query: 4048 HQARLCNPMPCE--AGCP----------AGMEVVTCANRC-PRRCSDLQEGIVCQDDQVC 4094
C P CE G P G + + N C C ++E + Q V
Sbjct: 2489 ECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVS 2548
Query: 4095 QKGCR---CPKGSLE--QDGGCVPIGHCDCTDA---QGHSWAPGSQHQ-DACNNCSC--Q 4143
CP G + C P C+ +A G PG D C C C Q
Sbjct: 2549 CPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQ 2608
Query: 4144 AGQLS--------CTAQPCP 4155
G +S T PCP
Sbjct: 2609 VGVISGFKLECRKTTCNPCP 2628
Score = 35.8 bits (81), Expect = 1.1
Identities = 80/350 (22%), Positives = 107/350 (30%), Gaps = 80/350 (22%)
Query: 1736 EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAAL------ 1789
++ Q C C D P C + T+T +C TCA
Sbjct: 2314 QNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRP----NFTCACRKEECKR 2369
Query: 1790 -------PGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISG--QVTCPPD 1840
P L + R+T+ C + C C + P T + G TC PD
Sbjct: 2370 VSPPSCPPHRLPTLRKTQCCDEYECA-CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPD 2428
Query: 1841 WPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQD------ 1894
C P GQ EG V C C D G R+ A C C+D
Sbjct: 2429 KVCVHRSTIYPVGQ-FWEEGCDV----CTC-TDMEDAVMGLRV-AQCSQKPCEDSCRSGF 2481
Query: 1895 ----------GR--PRRCRLNPDCAVDCGWSSW----SPWAKCLGPC-------GSQSIQ 1931
GR P C + SSW S WA PC + +
Sbjct: 2482 TYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVF 2541
Query: 1932 WSFRSSNNPR------PSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPC 1985
R+ + P+ PSG C+ C+ E E C G V G+ C
Sbjct: 2542 IQQRNVSCPQLEVPVCPSGFQLSCK-TSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC 2600
Query: 1986 RVCQCLHNL-----------TAHCSPYCPLGSCPQGWVLVEGTGESCCHC 2024
C+C+ + C+P CP G+ TGE C C
Sbjct: 2601 TTCRCMVQVGVISGFKLECRKTTCNP------CPLGYKEENNTGECCGRC 2644
Score = 34.3 bits (77), Expect = 3.3
Identities = 53/228 (23%), Positives = 71/228 (31%), Gaps = 68/228 (29%)
Query: 4053 CNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVC-QKGCRCPKGSLEQDGGC 4111
CN + CP G T N C C+ C D+VC + P G ++G
Sbjct: 2396 CNCVNSTVSCPLGYLASTATNDC--GCTT----TTCLPDKVCVHRSTIYPVGQFWEEGCD 2449
Query: 4112 VPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPC 4171
V C CTD +DA C+ +PC +++ C
Sbjct: 2450 V----CTCTDM-----------EDAVMGLRV----AQCSQKPCEDSCRSGFTYVLHEGEC 2490
Query: 4172 SHSC----------GPRGQQSRFRSSTSGSWAP--------EC---REE---QSQSQPCP 4207
C PRG S WA EC +EE Q ++ CP
Sbjct: 2491 CGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCP 2550
Query: 4208 Q---PSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAV 4252
Q P CP S Q C+ +C P CE E +
Sbjct: 2551 QLEVPVCP--------------SGFQLSCKTSACCP-SCRCERMEACM 2583
Score = 34.3 bits (77), Expect = 3.3
Identities = 25/102 (24%), Positives = 35/102 (34%), Gaps = 12/102 (11%)
Query: 2912 QGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCP----CQLHGQLYASGAMARLDSCNN 2967
Q + C P C L ++C P +C C L+G + G +D C
Sbjct: 2543 QQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTT 2602
Query: 2968 CTC------VSG-KMACTSERC-PVACGWSPWTLWSLCSCSC 3001
C C +SG K+ C C P G+ C C
Sbjct: 2603 CRCMVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRC 2644
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 606 bits (1562), Expect = e-172
Identities = 401/1235 (32%), Positives = 572/1235 (46%), Gaps = 123/1235 (9%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAG---AADSTWAVHLTPGDRCPQPGHCQRVTMG 251
C++W FHY+TFDG + F G C Y+ + AA + V L G +P RV +
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPV-VTRVVIK 135
Query: 252 PEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISV 311
+ ++++A N SV E + GL ++ GD++ +S L + + S + +
Sbjct: 136 AQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLEL 195
Query: 312 DHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQG 370
D + QT GLCG +NG P ++F L L FGN +L G C D
Sbjct: 196 DPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGPTEQCPD------- 246
Query: 371 CDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEACLFAYCAGAMAG 429
PL L P + + +CH+ L GP F +CHA V Y AC C
Sbjct: 247 --PLPL------PAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP 298
Query: 430 SGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEA 488
CATF Y + CA R WR P C R CP + +C S C +C
Sbjct: 299 ----------CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCS- 347
Query: 489 VGQGEEESCREECVSGCECPRG--------LFWNGTLCVPAAHCPCYYCRQRYVPGDTVR 540
+ C + CV GC CP G + +G C+P CPC + + Y PG +
Sbjct: 348 -NPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTSFN 404
Query: 541 QLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQ 600
C+ C C G W C CP C+V G H T+D + Y G C Y L +
Sbjct: 405 TTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGD--CSYVLSKKCADSS 462
Query: 601 LLILLEHGAC---DAGSCLHAISVSLE--DTHIQLRDSGAVLVNGQDVGLPWIGAEGLSV 655
+L E C D +CL A+++SL+ DT I+++ G V +N LP + A +++
Sbjct: 463 FTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLP-LSAANITL 521
Query: 656 RRASSAFLLLRWP-GAQVLWGLSDPV-AYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAG 713
SS F++++ G Q+L L + ++ LDP H Q+ GLCG F QNQ DDF +G
Sbjct: 522 FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSG 581
Query: 714 DVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILH--SSVFQECH 771
VE + AAFA+ ++ + C + ++ PC+ + +A C+ L +S F CH
Sbjct: 582 VVEATGAAFANTWKA--QAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCH 639
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVM--CP 828
+++ +PF+ C+ C C+ DCLC LS+Y CA +G WR+ M CP
Sbjct: 640 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 699
Query: 829 GGQEYRECAPACGQHC-GKPE---DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQL 884
Q Y AC C G E C V GC CP G + G CVP CPC
Sbjct: 700 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 759
Query: 885 GARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY---------APGA-C 934
APG E C C G +C C +VY PGA C
Sbjct: 760 HGTVLAPGEVVHDEGAVCSCTG-GKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 818
Query: 935 LLTCDSPSANHSCPAGS-----TDGCVCPPGTVLLDER-CVPPDLCPCRHSGQWYLPNAT 988
L +C H+ G GCVCPPG V C+ + CPC H+ Y P T
Sbjct: 819 LRSC------HTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGET 872
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVRE----- 1043
I+ DCN C CR R+W C+ + G C A G H++TFDG +++ G+CEY+L ++
Sbjct: 873 IRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDN 932
Query: 1044 -ASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTV-NGVSVTPPKVYTGP 1101
G F + +N+PCG +G TC+KA+ + +E + + G V G PP
Sbjct: 933 TTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPP------ 986
Query: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQ 1161
+R G+FL++ TH G+ + WD T V ++L ++GRV GLCG+FD +A ND +R
Sbjct: 987 -YKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRS 1044
Query: 1162 GVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVP 1221
+ A +SW+LSP CP+ PCT N R WA+ +C L P F C ++V
Sbjct: 1045 RSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVD 1104
Query: 1222 PQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE----- 1276
++YE C+ DAC CDSGGDCEC C+A+A YA C G V WR+ + C L C+
Sbjct: 1105 STKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPH 1164
Query: 1277 GG--QVYEACGPTCPPTCHEQHPEPGWHCQV-VACVEGCF--CPEGTLLHGGACLE-PAS 1330
GG Y+ CG C TC P HC V + +EGC+ CP ++ A
Sbjct: 1165 GGCEWHYQPCGAPCLKTCR----NPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQ 1220
Query: 1331 CPC-EWGRNSFPPGSVL--QKDCGNCTCQEGQWHC 1362
C C + N + G+ + ++C +C C C
Sbjct: 1221 CGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQC 1255
Score = 259 bits (661), Expect = 6e-68
Identities = 254/973 (26%), Positives = 369/973 (37%), Gaps = 201/973 (20%)
Query: 564 CAVGGDGHYLTFDGRSYSFWG------GQGCRYSLVQDYVKGQLLILLEHGACDAGSCLH 617
C+ GD HY TFDG + F G + CR + +D+ + L G + +
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCR-AAYEDFN-----VQLRRGLVGSRPVVT 130
Query: 618 AISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
+ + + ++ +G+VL+NGQ LP+ GL V ++ + LW
Sbjct: 131 RVVIKAQGLVLEA-SNGSVLINGQREELPY-SRTGLLVEQSGDYIKVSIRLVLTFLWNGE 188
Query: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQ-DDFLTPAGDVETSIAAFASKFQVAGKG-RCP 735
D A + LDP++A+Q GLCG F ++F A + + F + ++ G +CP
Sbjct: 189 DS-ALLELDPKYANQTCGLCGDFNGLPAFNEFY--AHNARLTPLQFGNLQKLDGPTEQCP 245
Query: 736 SEDSALLSPCTTHSQRHAFAEAAC-AILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGS 794
CT E C L F ECH LVD
Sbjct: 246 DPLPLPAGNCTDE-------EGICHRTLLGPAFAECHALVDS------------------ 280
Query: 795 DCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEY-RECAPACGQHCGKPEDCGEL 853
+AY CAQ+ P CP C EY R+CA A G+P +
Sbjct: 281 -------TAYLAACAQDLCRCP-----TCP--CATFVEYSRQCAHAG----GQPRN---- 318
Query: 854 GSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCT 913
W +C P LCP R P + +EC
Sbjct: 319 --------------W----RC--PELCP------RTCPLNMQHQECG------------- 339
Query: 914 ARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPG---TVLLD---ER 967
C TC +P C DGC CPPG TVL D
Sbjct: 340 ------------------SPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG 381
Query: 968 CVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDG 1027
C+P CPC H G+ Y P + C+ C C G W C G C G H T+D
Sbjct: 382 CLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDE 441
Query: 1028 LAFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEG--TVVHMLRGR 1083
+ G C Y+L ++ A FTV A+ CG + C KA+ + L+G T + +
Sbjct: 442 KLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADG 501
Query: 1084 AVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD--GGTRVLVQLSPQFRGR 1141
V +N + P L + F+++ T LGL LL +V V+L P +G+
Sbjct: 502 GVFLNSIYTQLPLSAANITL-FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQ 560
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEP-GDLPHPCTMNTHRAGW 1200
+ GLCG+F+ + ++D + GV+E T A++W+ C PC+++ +
Sbjct: 561 MCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENENY 620
Query: 1201 ARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
AR C L P F+ CH+ + P+ + C++D C C+ DC LC+A+++Y CA
Sbjct: 621 ARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDC--LCAALSSYVHACAA 678
Query: 1259 HGHHVRWRSQELCSL---QCEGGQVYEACGPTCPPTCHEQHPEPGWHCQV-VACVEGCFC 1314
G + +C+ C Q Y C PTC E C V V+GC C
Sbjct: 679 KGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLS-EADVTCSVSFVPVDGCTC 737
Query: 1315 PEGTLLH-GGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELV 1373
P GT L+ GAC+ CPC PG V+ + C+C G+ C
Sbjct: 738 PAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSC----------- 786
Query: 1374 PACAEGEALCQENGHCVPHGWL-CDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLA 1432
G +L + G P +L C N G++ C + C S HC+
Sbjct: 787 ----LGASLQKSTGCAAPMVYLDCSNSSAGTPGAE----CLRSCHTLDVGCFSTHCV--- 835
Query: 1433 LLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTC 1492
G PP L+ DG C+ D + T
Sbjct: 836 ----------------------------SGCVCPPGLVSDGSGGCIAEEDCPCVHNEATY 867
Query: 1493 VPGEVSCVD-GTC 1504
PGE VD TC
Sbjct: 868 KPGETIRVDCNTC 880
Score = 144 bits (364), Expect = 2e-33
Identities = 182/760 (23%), Positives = 275/760 (36%), Gaps = 167/760 (21%)
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAF---CPRELVYAPGACLL 936
C C+ + ++PG + +R C + N +HC F CP A L
Sbjct: 4946 CFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCN---QHCDIDRFQGACPTSPPPVSSAPLS 5002
Query: 937 T-CDSPSANHSCPAGSTDG-----------CVCPPGTVLLDERCVPPDLCPCRHSGQWYL 984
+ +P +++ P + CV VLLD + V C +H +
Sbjct: 5003 SPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLP---I 5059
Query: 985 PNATIQEDCNV---CVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLV 1041
+ + C+ C C W G HY TFDG ++T+ G C Y+L+
Sbjct: 5060 KVSDPSQPCDFHYECECICSMW--------------GGSHYSTFDGTSYTFRGNCTYVLM 5105
Query: 1042 REASGLF---TVSAQNLPCGASGLT----CTKALAVR-------LEGTVVHMLRGRAVTV 1087
RE F ++ N C AS C +AL++ L T+VH +
Sbjct: 5106 REIHARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILF 5165
Query: 1088 NGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCG 1147
+ + V+ G +S+ + LG+++ ++G F G CG
Sbjct: 5166 DQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCG 5225
Query: 1148 DFDGDASNDLRSRQGVLEPTAELAAHSWRL------------------SPLCP-EPGDLP 1188
+ +D R G + + A +W + SP P P
Sbjct: 5226 TCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTP 5285
Query: 1189 HPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
PC + C +L +F CH VPP + C+ D C G E C +
Sbjct: 5286 TPCP--------PQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQS 5333
Query: 1249 IATYADECARHGHHVRWRSQE--LCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVV 1306
+ YA+ C G WR LC L C +VY+ CGP P TC+ ++ P Q+
Sbjct: 5334 LEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSP----QLE 5389
Query: 1307 ACVEGCFCPEGTLL---HGGACLEPASCPCEWGRNSFP--PGSVLQKDCGNCTCQEG--- 1358
EGCFCPE +L H G C++ +CPC G + FP PG +C +C C EG
Sbjct: 5390 GMAEGCFCPEDQILFNAHMGICVQ--ACPCV-GPDGFPKFPGERWVSNCQSCVCDEGSVS 5446
Query: 1359 ------------------------------------QWHCGGDGGHCEELVPACAEG-EA 1381
+ C + C + +P C G E+
Sbjct: 5447 VQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQES 5506
Query: 1382 LC-QENGHCVPHGWLCDNQDDCGDGS-DEEGCAAPGCGEGQM-TCSSGHCLPLALLCDRQ 1438
+C QE G C P + C Q +G+ G PG M TC SG + C ++
Sbjct: 5507 ICTQEEGDCCP-TFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQC-QE 5564
Query: 1439 DDCGDGTDEPSYPCPQG-----LLACADGRCLPPALLC-DGHPDCLDAADEESCLGQVT- 1491
D C + T CPQG + G C+ A L DG P L+ S + T
Sbjct: 5565 DACNNTT------CPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTV 5618
Query: 1492 -----------CVPGEVSCVD-GTCLGAIQLCDGVWDCPD 1519
P SC D +C G+++ + C +
Sbjct: 5619 YLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEE 5658
Score = 138 bits (348), Expect = 1e-31
Identities = 148/557 (26%), Positives = 222/557 (39%), Gaps = 104/557 (18%)
Query: 41 PCASLDHYSRLGWRLDLPWSGRSGLTRS-PAPGLCPIYKPPETRPAKWNRTVRTCCPGWG 99
PCA+ YSR + G R+ P LCP R N + C
Sbjct: 298 PCATFVEYSR-------QCAHAGGQPRNWRCPELCP-------RTCPLNMQHQEC----- 338
Query: 100 GAHCTEALAKASP----EGHCFAMW------QCQLQAGSANASAGSLEECCARPWGQSWW 149
G+ CT+ + E HC C + ++ L +C G+++
Sbjct: 339 GSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYS 398
Query: 150 DGSS--QACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPS-ATCASWSGFHYRTF 206
G+S C SC+ G LW P TC+ G H T+
Sbjct: 399 PGTSFNTTCSSCTCS-------------------GGLWQCQDLPCPGTCSVQGGAHISTY 439
Query: 207 DGRHYHFLGRCTYLLA-GAADSTWAV-------HLTPGDRCPQPGHCQRVTM----GPEE 254
D + Y G C+Y+L+ ADS++ V LT + C + VT+ G
Sbjct: 440 DEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENC-----LKAVTLSLDGGDTA 494
Query: 255 VLIQA-GNV---SVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLG--VVVRLDRTGSIS 308
+ +QA G V S+ QL + L S ++V+ GLG ++V+L +
Sbjct: 495 IRVQADGGVFLNSIYTQLPLSAANITLFTPS----SFFIVVQTGLGLQLLVQLVPLMQVF 550
Query: 309 ISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVA 368
+ +D GQ GLCG +N DDF G + A F N+W+ +++ C +A
Sbjct: 551 VRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWK---AQAACANARNSF 607
Query: 369 QGCDPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGA 426
+ DP L VE + A+ C +L + F +CH+ ++P +H C+F C
Sbjct: 608 E--DPCSL---SVENENY---ARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTC--- 656
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERL---CPGGQLYSDCVSLCP 483
E + +CA +SYV ACA + + + + G C + CP Q Y+ V C
Sbjct: 657 ----NCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQ 712
Query: 484 PSCEAVGQGEEE-SCREECVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQ 541
P+C + + + S V GC CP G F N CVPA CPCY PG+ V
Sbjct: 713 PTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHD 772
Query: 542 LCNPCVCRDGRWHCAQA 558
C C G+ C A
Sbjct: 773 EGAVCSCTGGKLSCLGA 789
Score = 136 bits (342), Expect = 6e-31
Identities = 143/530 (26%), Positives = 206/530 (38%), Gaps = 67/530 (12%)
Query: 560 CPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK--GQLLILLEHGACDAGS--- 614
C C++ G HY TFDG SY+F G C Y L+++ G L + L++ C A +
Sbjct: 5074 CECICSMWGGSHYSTFDGTSYTFRG--NCTYVLMREIHARFGNLSLYLDNHYCTASATAA 5131
Query: 615 ---CLHAISVSLEDTHIQLRDSGAVLVNGQDVGL---------PWIGAEGLSVRRASSAF 662
C A+S+ + I L +V+G++ GL G+ V +
Sbjct: 5132 AARCPRALSIHYKSMDIVLT---VTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTT 5188
Query: 663 LLLRWPGAQVLWGLSDPVAYITLDPRHAH-QVQGLCGTFTQNQQDDFLTPAGDVETSIAA 721
+ + P V + V L H +G CGT T NQ+DD L G S
Sbjct: 5189 MRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKD 5248
Query: 722 FASKFQV--AGKGRC--PSEDSALLSPC----TTHSQRHAFAEAACAILHSSVFQECHRL 773
A + V + K C P+ SP +T + + C ++ S VF ECH L
Sbjct: 5249 MAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNL 5308
Query: 774 VDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQT--LCPVMCPGGQ 831
V PF+ C++ C + C L AYA C G WR T LC + CP +
Sbjct: 5309 VPPGPFFNACISD--HCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTK 5366
Query: 832 EYRECAPACGQHCGKPEDCGELGSCVAGCNCPLG-LLWDPE-GQCVPPSLCPCQLGARRY 889
Y+ C P C +L GC CP +L++ G CV CPC +G +
Sbjct: 5367 VYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICV--QACPC-VGPDGF 5423
Query: 890 A--PGSATMKECNRCICQERGL-WNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHS 946
PG + C C+C E + C C +Q P PG +T P A +
Sbjct: 5424 PKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPP--CNRPG--FVTVTRPRAENP 5479
Query: 947 CPAGSTDGC----------VCPPG--TVLLDER--CVPPDLCP---CRHSGQWYLPNATI 989
C + C VCPPG ++ E C P C C ++G +Y AT
Sbjct: 5480 CCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATF 5539
Query: 990 QE--DCNVCVC-RGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGAC 1036
C++C C G T Q + C + P + +A G C
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGEC 5589
Score = 114 bits (285), Expect = 3e-24
Identities = 101/424 (23%), Positives = 153/424 (36%), Gaps = 61/424 (14%)
Query: 158 SCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC 217
+C ++HLP S P+ Q H C+ W G HY TFDG Y F G C
Sbjct: 5051 TCVNKHLPIKVSDPS----------QPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNC 5100
Query: 218 TYLLAGAADSTWAV-------HLTPGDRCPQPGHCQR--------------VTM--GPEE 254
TY+L + + H C R VTM G EE
Sbjct: 5101 TYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEE 5160
Query: 255 VLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSI-SISVDH 313
LI + P + +G+ + LG + + V + G + + +
Sbjct: 5161 GLILFDQI-------PVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPY 5213
Query: 314 ELW-GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGS-ESGCLDAVEVAQGC 371
L+ T+G CG DD ++ G A +W +P S + GC
Sbjct: 5214 SLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTA 5273
Query: 372 DPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSG 431
P + + P Q +C +L F +CH V P + AC+ +C
Sbjct: 5274 SPAAPVSSTPTP--TPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC-------- 5323
Query: 432 QEGRQQAVCATFASYVQACARRHIHIRWR--KPGFCERLCPGGQLYSDCVSLCPPSCEAV 489
GR + C + +Y + C R + WR G C+ CP ++Y C + P +C +
Sbjct: 5324 -RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSR 5382
Query: 490 GQGEEESCREECVSGCECPRG-LFWNGTLCVPAAHCPCYYCRQ-RYVPGDTVRQLCNPCV 547
Q + E GC CP + +N + + CPC PG+ C CV
Sbjct: 5383 NQSPQ---LEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCV 5439
Query: 548 CRDG 551
C +G
Sbjct: 5440 CDEG 5443
Score = 107 bits (266), Expect = 4e-22
Identities = 113/425 (26%), Positives = 166/425 (39%), Gaps = 72/425 (16%)
Query: 188 HQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA------GAADSTWAVHLTPGDRCPQ 241
H+ TC ++ H+ TFDG Y F G C Y+LA T+ + +T C
Sbjct: 891 HRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRI-VTENIPCGT 949
Query: 242 PG----HCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGV 297
G ++ + E+++Q G + P G ++++G +LV+ G+
Sbjct: 950 TGTTCSKAIKLFVESYELILQEGTFKAVAR-GPGGDP----PYKIRYMGIFLVIETH-GM 1003
Query: 298 VVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGS 357
V DR S+ I + + G+ GLCG ++ +DF + A FGNSW+L S
Sbjct: 1004 AVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPS 1063
Query: 358 ESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHE 416
C DA+ C ++ AQ C +L GP F C +QV +Y+E
Sbjct: 1064 ---CPDALAPKDPC---------TANPFRKSWAQKQC-SILHGPTFAACRSQVDSTKYYE 1110
Query: 417 ACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLC----PGG 472
AC+ CA SG G + C A+Y QAC + + WR P C C P G
Sbjct: 1111 ACVNDACA---CDSG--GDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHG 1165
Query: 473 QL---YSDCVSLCPPSCE------AVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAH 523
Y C + C +C V E C +C P F+N A
Sbjct: 1166 GCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-----PSQPFFNEDQMKCVAQ 1220
Query: 524 CPCYYCRQRY------VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDG 577
C CY Y VP + C C C CA +L C T++
Sbjct: 1221 CGCYDKDGNYYDVGARVP---TAENCQSCNCTPSGIQCAHSLEACTC---------TYED 1268
Query: 578 RSYSF 582
R+YS+
Sbjct: 1269 RTYSY 1273
Score = 85.9 bits (211), Expect = 1e-15
Identities = 60/214 (28%), Positives = 77/214 (35%), Gaps = 20/214 (9%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLLHN-GTCVPPTACPC 4874
CP Q + +C C L + P GC CP G L++ G CVP CPC
Sbjct: 698 CPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 757
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPG----ETWQ 4930
H L PG V+ C C GG SC Q G +
Sbjct: 758 YAHGTV-------------LAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYL 804
Query: 4931 QVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLG 4990
+ G CL T S+ SGCVC PG +G C+ E+ C C H
Sbjct: 805 DCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNE 864
Query: 4991 RPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
+ PG + C +C C + R C+ TC
Sbjct: 865 ATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTC 898
Score = 78.2 bits (191), Expect = 2e-13
Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 20/143 (13%)
Query: 4030 SCSSPPSKNGGAPCAGERHQARLCN-----------PMPCEAGCPAGMEVVTCANRCPRR 4078
+C+ + PCA +R C P C CP M+ C + C
Sbjct: 286 ACAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDT 345
Query: 4079 CSDLQEGIVCQDDQVCQKGCRCPKG---SLEQD---GGCVPIGHCDCTDAQGHSWAPGSQ 4132
CS+ Q +C+D C GC CP G ++ D GC+P+G C CT G +++PG+
Sbjct: 346 CSNPQRAQLCEDH--CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTS 402
Query: 4133 HQDACNNCSCQAGQLSCTAQPCP 4155
C++C+C G C PCP
Sbjct: 403 FNTTCSSCTCSGGLWQCQDLPCP 425
Score = 77.8 bits (190), Expect = 3e-13
Identities = 98/384 (25%), Positives = 145/384 (37%), Gaps = 74/384 (19%)
Query: 1689 PEEQGCGAWGPW------SPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNC-----PGPEH 1737
P+ + G W P SP P S T P C + V C PGP
Sbjct: 5256 PDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGP-- 5313
Query: 1738 QSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTR 1797
F AC S+ CRG + + C S + C A G+ S
Sbjct: 5314 -----FFNAC--------------ISDHCRGRL--EVPCQSLEAYAELCRAR--GVCSDW 5350
Query: 1798 QTKPCPQDGCPNATCSGELMFQPCAPC-PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVL 1856
+ G + TC +++PC P P TC+ + P + GC+CPE Q+L
Sbjct: 5351 RGAT---GGLCDLTCPPTKVYKPCGPIQPATCNSRNQS----PQLEGMAEGCFCPEDQIL 5403
Query: 1857 GSEGWCVWPRQCPCL-VDGARYWPGQRIKADCQLCICQDG------RPRRCRLN---PDC 1906
+ + + CPC+ DG +PG+R ++CQ C+C +G +P C P C
Sbjct: 5404 FNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC 5463
Query: 1907 AVDCGWSSWSPWAKCLGPCGSQSI----QWSFRSSNNPRPSGRGRQCRGIHRKARRCQTE 1962
+ P A+ PC +++ + S P G+ C + C T
Sbjct: 5464 NRPGFVTVTRPRAE--NPCCPETVCVCNTTTCPQSLPVCPPGQESIC--TQEEGDCCPTF 5519
Query: 1963 PC--EGCEHQGQVHRVGERWHGG-PCRVCQCL----HNLTAHC-SPYCPLGSCPQGWVLV 2014
C + C + G + VG + G PC +C CL + T C C +CPQG+
Sbjct: 5520 RCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYK 5579
Query: 2015 EGTGESCCHC----ALPGENQTVQ 2034
G+ C C L + Q VQ
Sbjct: 5580 RVAGQCCGECVQTACLTPDGQPVQ 5603
Score = 76.6 bits (187), Expect = 6e-13
Identities = 100/409 (24%), Positives = 128/409 (31%), Gaps = 118/409 (28%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLL---HNGTCVPPTACPC 4874
CPP +V C P C E GC CP Q+L H G CV ACPC
Sbjct: 5362 CPPTKVYKPCGPIQPATCNSRNQSPQL--EGMAEGCFCPEDQILFNAHMGICVQ--ACPC 5417
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAP 4934
P G PG NC CVC G+ S V C+ P + Q P
Sbjct: 5418 VG---PDGFPKF---------PGERWVSNCQSCVCDEGSVS---VQCKPLPCDAQGQPPP 5462
Query: 4935 -------------GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGH---FRSQAGPC 4978
E C +T N T + VC PG + G C
Sbjct: 5463 CNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLP-------VCPPGQESICTQEEGDC 5515
Query: 4979 VPEDHCE---CWHLGRPHLPGSEWQEA--CESCLCLSGRPV-----CTQH-CSPLTCAQG 5027
P C C + G + G+ + A C C CLSG C + C+ TC QG
Sbjct: 5516 CPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQG 5575
Query: 5028 EEMVLEPGSCCPSCRREA---PE---------------------------------EQSP 5051
E G CC C + A P+ Q
Sbjct: 5576 FEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPA 5635
Query: 5052 SCQLLTELRNFTK--GTCYL---------------------DQVEVSYCSGYCPSSTHVM 5088
SC ++ R + G CY +V +++C G CP ++
Sbjct: 5636 SCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTILWHQGCETEVNITFCEGSCPGASKYS 5695
Query: 5089 PEEPYLQSQCDCCSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQCS 5137
E +Q QC CC R E V L C G + C C+
Sbjct: 5696 AEAQAMQHQCTCCQERRVHEETV---PLHCPNGSAILHTYTHVDECGCT 5741
Score = 76.3 bits (186), Expect = 8e-13
Identities = 38/89 (42%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
Query: 2634 PCPPSCLDPKANRSCSGHCVEGCRCPPG---LLLHD---TRCLPLSECPCLVGEELKWPG 2687
PC +C +P+ + C HCV+GC CPPG +L D + CLPL +CPC G PG
Sbjct: 341 PCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPG 400
Query: 2688 VSFLLGNCSQCVCEKGELLCQPGGCPLPC 2716
SF CS C C G CQ CP C
Sbjct: 401 TSFNT-TCSSCTCSGGLWQCQDLPCPGTC 428
Score = 71.6 bits (174), Expect = 2e-11
Identities = 43/138 (31%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNT-QPCTAQCPENMLFRSAEQCHQE-GGPCPRLCLTQGP 2914
C++ C Q R+ + C CP NM HQE G PC C
Sbjct: 299 CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-------HQECGSPCTDTCSNPQR 351
Query: 2915 GIECTGFCAPGCTCPPGLF------LHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNC 2968
C C GC CPPG + ++ CLP QCPC G+ Y+ G +C++C
Sbjct: 352 AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFN-TTCSSC 410
Query: 2969 TCVSGKMACTSERCPVAC 2986
TC G C CP C
Sbjct: 411 TCSGGLWQCQDLPCPGTC 428
Score = 70.5 bits (171), Expect = 4e-11
Identities = 109/405 (26%), Positives = 143/405 (35%), Gaps = 109/405 (26%)
Query: 3216 AVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHC--SRSCGGGLR 3273
A P + P P P P PLC + L Q P GP+ + S C G L
Sbjct: 5276 AAPVSSTPTPTPCPPQPLC-------DLMLSQVFAECHNLVPPGPFFNACISDHCRGRL- 5327
Query: 3274 SRTRACDQPPPQGLGDYCEGPRAQGEVCQ----------ALPCPVTNCTAIEGAEYSPCG 3323
+ P Q L Y E RA+G VC L CP T Y PCG
Sbjct: 5328 -------EVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKV-------YKPCG 5372
Query: 3324 PPCPRSCDDLVHC--VWRCQPGCYCPPGQVL-SSNGAICVQPGHCSCLDLLTGQRHHPGA 3380
P P +C+ + GC+CP Q+L +++ ICVQ C C+ G PG
Sbjct: 5373 PIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVG-PDGFPKFPGE 5429
Query: 3381 RLARPDGCNHCTCLEGRLN--CTDLPCPVPGGWCPWSE-------WTMCSQPCRGQTRSR 3431
R C C C EG ++ C LPC G P + PC +T
Sbjct: 5430 RWV--SNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCV 5487
Query: 3432 SRACACP-----TPQHGGAPCTGEAGEAGAQHQREACPSY----ATCPVDGAW---GPWG 3479
CP P + CT E G + CP++ C +G + G
Sbjct: 5488 CNTTTCPQSLPVCPPGQESICTQEEG--------DCCPTFRCRPQLCSYNGTFYGVGATF 5539
Query: 3480 PWS-PCDMCLGQSHRSR---------ACSRPPTPEG------GRPCPGNHTQS------- 3516
P + PC MC S ++ AC+ P+G C G Q+
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5599
Query: 3517 RPCQENST-------QCT----DCGGGQSLHPCGQPCPRSCQDLS 3550
+P Q N T CT + GG L P P SC D+S
Sbjct: 5600 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLL---TPQPASCPDVS 5641
Score = 68.2 bits (165), Expect = 2e-10
Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 31/153 (20%)
Query: 4377 CSCRVLVQ--QRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGS 4434
C C V+ ++ H G R R C R +C + CGS
Sbjct: 297 CPCATFVEYSRQCAHAGGQPRNWRCPELCPR----------------TCPLNMQHQECGS 340
Query: 4435 PCAGLCATHLSHQLCQDLPPCQPGCYCPKG----LLEQA--GGCIPPEECNCWHTSAAGA 4488
PC C+ QLC+D C GC+CP G +L+ GC+P +C C H
Sbjct: 341 PCTDTCSNPQRAQLCED--HCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH-----G 393
Query: 4489 GMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521
G T +PG C C C G C C G
Sbjct: 394 GRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPG 426
Score = 67.0 bits (162), Expect = 5e-10
Identities = 56/200 (28%), Positives = 83/200 (41%), Gaps = 37/200 (18%)
Query: 4338 MAKADPTCNSTFLHLDTQGCYSGPCPEE---CVWSSWSSWTRCSC----RVLVQQRYRHQ 4390
+++AD TC+ +F+ +D C +G + CV + C C VL H
Sbjct: 718 LSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQ-----ECPCYAHGTVLAPGEVVHD 772
Query: 4391 GPA------SRGARAGAPCTRLDGHFRPCLISNCSEDSC-TPPFE-FHACGSPCAGLCAT 4442
A + + GA + G P + +CS S TP E +C + G +T
Sbjct: 773 EGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFST 832
Query: 4443 HLSHQLCQDLPPCQPGCYCPKGLLEQ-AGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLG 4501
H C GC CP GL+ +GGCI E+C C H A T PG+ +++
Sbjct: 833 H-----------CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEA-----TYKPGETIRVD 876
Query: 4502 CKECECRRGELHCTSQGCQG 4521
C C CR C+ + C G
Sbjct: 877 CNTCTCRNRRWECSHRLCLG 896
Score = 66.2 bits (160), Expect = 8e-10
Identities = 55/201 (27%), Positives = 70/201 (34%), Gaps = 16/201 (7%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEG-IVCQDDQVCQKGCRCPKGSLEQDGG-CVPIGHCDC 4119
CP + C C L E + C V GC CP G+ D G CVP C C
Sbjct: 698 CPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 757
Query: 4120 TDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCA-------WSHWSAWSP-- 4170
A G APG D CSC G+LSC T CA S+ SA +P
Sbjct: 758 Y-AHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGA 816
Query: 4171 -CSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWL 4229
C SC SG P + CP C+ + G++ +
Sbjct: 817 ECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCP--CVHNEATYKPGET-I 873
Query: 4230 QGECQRCSCTPEGVICEDTEC 4250
+ +C C+C C C
Sbjct: 874 RVDCNTCTCRNRRWECSHRLC 894
Score = 65.9 bits (159), Expect = 1e-09
Identities = 72/278 (25%), Positives = 86/278 (30%), Gaps = 90/278 (32%)
Query: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD-GLCVPPAHCRCQYQPGAMGIPENQ 3600
C +C+ LS V S C CP G D G CVP C C Y G +
Sbjct: 711 CQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC-YAHGTV------ 763
Query: 3601 SRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS 3660
L PGEVV C+C G L S
Sbjct: 764 -------------LAPGEVVHDEGAVCSCTGGKL-------------------------S 785
Query: 3661 CGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVT 3720
C G +S CA P CS AG P R C T
Sbjct: 786 CLGASLQKSTGCAAPMV------YLDCSNS---SAGTPGAECLRSCH------------T 824
Query: 3721 QQVGCFSEGCEEGCHCPEGTFQHRL-ACV--QECPCVLTAWLLQELGATIGDPGQPLGPG 3777
VGCFS C GC CP G C+ ++CPCV AT
Sbjct: 825 LDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNE-------AT----------- 866
Query: 3778 DELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+T+R C C+C + + CS C +G
Sbjct: 867 --YKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYG 902
Score = 63.5 bits (153), Expect = 5e-09
Identities = 53/195 (27%), Positives = 66/195 (33%), Gaps = 29/195 (14%)
Query: 2811 SCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC---DGGIQTRGRSCSSLAPGDTTC 2867
+C G + + CS PV TC A D G + C A G
Sbjct: 714 TCRGLSEADVTCSVSFVPVDGC--------TCPAGTFLNDAGACVPAQECPCYAHGTVLA 765
Query: 2868 PGP--HSQTRDCNTQPCTAQC-------------PENMLFRSAEQCHQEGGPCPRLCLTQ 2912
PG H + C+ C P L S G C R C T
Sbjct: 766 PGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTL 825
Query: 2913 GPGIECTGFCAPGCTCPPGLFLH-NASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCV 2971
G T C GC CPPGL + C+ CPC + Y G R+D CN CTC
Sbjct: 826 DVGCFST-HCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVD-CNTCTCR 883
Query: 2972 SGKMACTSERCPVAC 2986
+ + C+ C C
Sbjct: 884 NRRWECSHRLCLGTC 898
Score = 60.5 bits (145), Expect = 4e-08
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 8/105 (7%)
Query: 3082 CAGPVPGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGML------LLNN 3134
C P CP + Q +C +C+ + C GC CP G + ++
Sbjct: 321 CPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHS 380
Query: 3135 VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
C+P CPC H G Y PG++ C +C+C SG + C PC
Sbjct: 381 GCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTC-SGGLWQCQDLPC 424
Score = 59.7 bits (143), Expect = 7e-08
Identities = 32/96 (33%), Positives = 43/96 (44%), Gaps = 11/96 (11%)
Query: 3318 EYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQVLSSNGAI----CVQPGHCSCLDL 3370
++ CG PC +C + C C GC+CPPG+ + I C+ G C C
Sbjct: 334 QHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH- 392
Query: 3371 LTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
G+ + PG C+ CTC G C DLPCP
Sbjct: 393 -GGRTYSPGTSFNTT--CSSCTCSGGLWQCQDLPCP 425
Score = 59.3 bits (142), Expect = 1e-07
Identities = 41/150 (27%), Positives = 63/150 (42%), Gaps = 12/150 (8%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQPCTA---QCPENMLFRSAEQCHQEGGPCPRLCLTQG 2913
C++L+ C Q D CT CP++ + Q P
Sbjct: 666 CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQ-----PTCRGLSE 720
Query: 2914 PGIECTGFCAP--GCTCPPGLFLHNA-SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTC 2970
+ C+ P GCTCP G FL++A +C+P +CPC HG + A G + D C+C
Sbjct: 721 ADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVH-DEGAVCSC 779
Query: 2971 VSGKMACTSERCPVACGWSPWTLWSLCSCS 3000
GK++C + G + ++ CS S
Sbjct: 780 TGGKLSCLGASLQKSTGCAAPMVYLDCSNS 809
Score = 59.3 bits (142), Expect = 1e-07
Identities = 116/476 (24%), Positives = 163/476 (34%), Gaps = 100/476 (21%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF---QHRLACVQECPC 3753
CP ++Y+ C P + + + + Q+ EG EGC CPE H CVQ CPC
Sbjct: 5362 CPPTKVYKPCGPIQPATCNSRNQSPQL----EGMAEGCFCPEDQILFNAHMGICVQACPC 5417
Query: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLS--CSLDDCFEAD 3811
V G G P PG+ S +C +C C G +S C C +A
Sbjct: 5418 V-------------GPDGFPKFPGERWVS------NCQSCVCDEGSVSVQCKPLPC-DAQ 5457
Query: 3812 GGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEGS 3871
G P PC+R G T TR P C P C + CP +
Sbjct: 5458 G-----QP-PPCNRP--GFVTVTR--------PRAENPCC--PETVCVCNTTTCPQS--- 5496
Query: 3872 TVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCT---MGDPLQ-ERPCN 3927
PV P S C++ D P +R R +LC N T +G PC+
Sbjct: 5497 --LPVC-------PPGQESICTQEEGD-CCPTFRCRPQLCSYNGTFYGVGATFPGALPCH 5546
Query: 3928 LPSCTELPV-CPGPGCGAGNCSWTSWAPWEPCSRSCG--VGQQRRLRAYRPPGPGGHWCP 3984
+ +C P C C+ T+ R G G+ + P G
Sbjct: 5547 MCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNE 5606
Query: 3985 NILTAYQERRFCNLRACPVPGGWSRWSPW-SWCD--RSCGGGQSLRSRSCSSPPSKNGGA 4041
+ ++ + C + C GG +P + C SC G SLR C
Sbjct: 5607 TWVNSHVDN--CTVYLCEAEGGVHLLTPQPASCPDVSSCRG--SLRKTGCC--------Y 5654
Query: 4042 PCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCP 4101
C + Q R+ + GC + + C CP E Q C C
Sbjct: 5655 SCEEDSCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTC-----CQ 5709
Query: 4102 KGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPP 4157
+ + ++ VP+ HC A H++ H D C C C P PP
Sbjct: 5710 ERRVHEE--TVPL-HCPNGSAILHTYT----HVD---ECGCTP---FCVPAPMAPP 5752
Score = 57.8 bits (138), Expect = 3e-07
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 27/119 (22%)
Query: 4815 CPE-----CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQ-------LLH 4862
CPE CP C + C C + Q +C ++ C GC CP G+ + H
Sbjct: 321 CPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC-EDHCVDGCFCPPGRSCTVLDDITH 379
Query: 4863 NGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
+G C+P CPCT + PGT C+ C C GG + C + C
Sbjct: 380 SG-CLPLGQCPCTHGGRTYS-------------PGTSFNTTCSSCTCSGGLWQCQDLPC 424
Score = 57.4 bits (137), Expect = 4e-07
Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 17/98 (17%)
Query: 4676 LDCAN--------QCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGR--CVPISSCRC 4725
LDC+N +C SC L V C C GC CPPG LV DG C+ C C
Sbjct: 804 LDCSNSSAGTPGAECLRSCHTL--DVGCFSTHCVSGCVCPPG-LVSDGSGGCIAEEDCPC 860
Query: 4726 GLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC 4763
A P + +++DC CTC N C H+ C
Sbjct: 861 VHNEATYK----PGETIRVDCNTCTCRNRRWECSHRLC 894
Score = 55.8 bits (133), Expect = 1e-06
Identities = 50/179 (27%), Positives = 63/179 (35%), Gaps = 21/179 (11%)
Query: 1732 CPGPEHQSQACFTAACPVDG----------EWSTWSPWSVCSEPCRGTMTRQRQCHSPQN 1781
C G C + PVDG + P C PC T +
Sbjct: 715 CRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQEC--PCYAHGTVLAPGEVVHD 772
Query: 1782 GGRTCAALPGGLHSTRQTKPCPQDGCPNAT----CSGELMFQPCAPCPLTCDDISGQVTC 1837
G C+ GG S GC CS P A C +C + V C
Sbjct: 773 EGAVCSCT-GGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD--VGC 829
Query: 1838 PPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGR 1896
C S GC CP G V G C+ CPC+ + A Y PG+ I+ DC C C++ R
Sbjct: 830 FSTH-CVS-GCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRR 886
Score = 55.5 bits (132), Expect = 1e-06
Identities = 50/217 (23%), Positives = 67/217 (30%), Gaps = 62/217 (28%)
Query: 4703 GCRCPPGQLVQD-GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQ 4761
GC CP G + D G CVP C C LAP + V + C+C L
Sbjct: 734 GCTCPAGTFLNDAGACVPAQECPCYAHGT----VLAPGEVVHDEGAVCSCTGGKL----- 784
Query: 4762 ECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPG 4821
C G ++++ C AP D C G
Sbjct: 785 ----------------SCLGASLQKSTGC-----AAPMVYLD-----------CSNSSAG 812
Query: 4822 QVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLH-NGTCVPPTACPCTQHSLP 4880
+ C SC L C C GC CP G + +G C+ CPC +
Sbjct: 813 TPGAECLRSCHTL------DVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEAT 866
Query: 4881 WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS 4917
+ PG + +C C C + CS
Sbjct: 867 Y-------------KPGETIRVDCNTCTCRNRRWECS 890
Score = 52.8 bits (125), Expect = 9e-06
Identities = 104/434 (23%), Positives = 150/434 (34%), Gaps = 122/434 (28%)
Query: 2634 PC----PPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRC-LPLSECPCLVGEEL-KWPG 2687
PC P +C + G EGC CP +L + + + CPC+ + K+PG
Sbjct: 5370 PCGPIQPATCNSRNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPG 5428
Query: 2688 VSFLLGNCSQCVCEKGELLCQPGGC-PLPCGWSAWSSWAPCDR-SCGSGVRARFRSPSNP 2745
++ NC CVC++G + Q C PLPC A PC+R + R R +P P
Sbjct: 5429 ERWV-SNCQSCVCDEGSVSVQ---CKPLPC--DAQGQPPPCNRPGFVTVTRPRAENPCCP 5482
Query: 2746 PAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCP 2805
VC T ++C QS +CP
Sbjct: 5483 ETV-----------------CVCNT-----------TTCPQSL-------------PVCP 5501
Query: 2806 SPGDSSC---PGDATQEEPCSPPVCPV-PSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLA 2861
+S C GD C P +C + +G+ A + + PC C+ L+
Sbjct: 5502 PGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPG-ALPC--------HMCTCLS 5552
Query: 2862 PGDTTCPGPHSQTRDCNTQPCTAQCPENMLF-RSAEQCHQEGGPCPR-LCLT-QGPGIE- 2917
GDT P Q CN CP+ + R A QC G C + CLT G ++
Sbjct: 5553 -GDTQDPTVQCQEDACN----NTTCPQGFEYKRVAGQC---CGECVQTACLTPDGQPVQL 5604
Query: 2918 -----------CTGFCAPGCTCPPGLFL---HNASCLPRSQCPCQLHGQLYASGAMARLD 2963
CT + C G+ L ASC S C G++ +
Sbjct: 5605 NETWVNSHVDNCTVYL---CEAEGGVHLLTPQPASCPDVSSC----------RGSLRKTG 5651
Query: 2964 SCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAE 3023
C +C + C V + LW C + F G+ P A+ AE
Sbjct: 5652 CC---------YSCEEDSCQVRINTT--ILWHQ---GCETEVNITFCEGSCPGASKYSAE 5697
Query: 3024 CQGPTMEAEFCSLR 3037
Q + C R
Sbjct: 5698 AQAMQHQCTCCQER 5711
Score = 51.6 bits (122), Expect = 2e-05
Identities = 51/205 (24%), Positives = 72/205 (35%), Gaps = 56/205 (27%)
Query: 2531 PLPGGSCPRDRFRSQS----------CFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQR 2580
P+ G +CP F + + C+ +A + + CS C GG S
Sbjct: 731 PVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCS--CTGGKLS--- 785
Query: 2581 SCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCL 2640
C GAS +++ T C VY+ C CL
Sbjct: 786 -------------CLGASLQKS----------TGCAAPMVYLD---CSNSSAGTPGAECL 819
Query: 2641 DPKANRSC--------SGHCVEGCRCPPGLLLHDT-RCLPLSECPCLVGEELKWPGVSFL 2691
RSC S HCV GC CPPGL+ + C+ +CPC+ E PG +
Sbjct: 820 -----RSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIR 874
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+ +C+ C C C C C
Sbjct: 875 V-DCNTCTCRNRRWECSHRLCLGTC 898
Score = 51.6 bits (122), Expect = 2e-05
Identities = 71/280 (25%), Positives = 98/280 (35%), Gaps = 50/280 (17%)
Query: 3090 CPRDKQWLDCAQ-GPASC-AELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDCPC 3144
CP K + C PA+C + +P+ GC CP +L N +CV Q CPC
Sbjct: 5362 CPPTKVYKPCGPIQPATCNSRNQSPQLEGMA--EGCFCPEDQILFNAHMGICV--QACPC 5417
Query: 3145 AH-EGHLYPPGSTVVRPCENCSCVSGLIA-NCSSWPC-AEGEPTWSPWTPWSQCSASCGP 3201
+G PG V C++C C G ++ C PC A+G+P P ++
Sbjct: 5418 VGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQP-----PPCNRPGFVTVT 5472
Query: 3202 ARCHRHRFCARSPSAVPSTVAPLPLPATP---TPLCSGPEAEEEP---CLLQGCDRAGGW 3255
+ C + +T P LP P +C+ E + P C Q C G +
Sbjct: 5473 RPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTF 5532
Query: 3256 GPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIE 3315
G + G L C L + P Q CQ C T C +
Sbjct: 5533 YGVG------ATFPGALPCHMCTC-------LSGDTQDPTVQ---CQEDACNNTTCP--Q 5574
Query: 3316 GAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSN 3355
G EY C C Q C P GQ + N
Sbjct: 5575 GFEYKRVAGQCCGEC---------VQTACLTPDGQPVQLN 5605
Score = 51.2 bits (121), Expect = 3e-05
Identities = 55/218 (25%), Positives = 76/218 (34%), Gaps = 45/218 (20%)
Query: 3435 CACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRS 3494
C P P G CT E G H+ P++A C + D+C R
Sbjct: 244 CPDPLPLPAGN-CTDEEGIC---HRTLLGPAFAECHALVDSTAYLAACAQDLC-----RC 294
Query: 3495 RACSRPPTPEGGRPCP--GNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPG 3552
C E R C G ++ C E + C CG PC +C +
Sbjct: 295 PTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT--CPLNMQHQECGSPCTDTCSNPQRA 352
Query: 3553 SVCQPGSVGCQPTCGCPLGQ-------LSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAG 3605
+C+ C C CP G+ ++ G C+P C C + G
Sbjct: 353 QLCEDH---CVDGCFCPPGRSCTVLDDITHSG-CLPLGQCPCTH---------------G 393
Query: 3606 SRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
R S PG C +CTC G+ QCQ++P CP
Sbjct: 394 GRTYS-----PGTSFNTTCSSCTCSGGLWQCQDLP-CP 425
Score = 50.8 bits (120), Expect = 3e-05
Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 8/91 (8%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGP-----CVPEDHCECWHLGRPHL 4994
C TC N + Q C GC C PG + C+P C C H GR +
Sbjct: 342 CTDTC--SNPQRAQL-CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYS 398
Query: 4995 PGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
PG+ + C SC C G C P TC+
Sbjct: 399 PGTSFNTTCSSCTCSGGLWQCQDLPCPGTCS 429
Score = 50.8 bits (120), Expect = 3e-05
Identities = 51/169 (30%), Positives = 62/169 (36%), Gaps = 28/169 (16%)
Query: 3239 AEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQG 3298
A+E PC G A G + CS C GG S C G Q
Sbjct: 752 AQECPCYAHGTVLAPGEVVHDEGAVCS--CTGGKLS----------------CLGASLQK 793
Query: 3299 EVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDL-VHCV-WRCQPGCYCPPGQVLSSNG 3356
A P +C+ + G C RSC L V C C GC CPPG V +G
Sbjct: 794 STGCAAPMVYLDCS---NSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSG 850
Query: 3357 AICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
C+ C C+ + PG + R D CN CTC R C+ C
Sbjct: 851 G-CIAEEDCPCVH--NEATYKPGETI-RVD-CNTCTCRNRRWECSHRLC 894
Score = 50.4 bits (119), Expect = 4e-05
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 9/86 (10%)
Query: 3090 CPRDKQWLDCAQGPASCAELSAPRGTNQT--------CHPGCHCPSGMLLLNNV-CVPTQ 3140
C +LDC+ A R + C GC CP G++ + C+ +
Sbjct: 797 CAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEE 856
Query: 3141 DCPCAHEGHLYPPGSTVVRPCENCSC 3166
DCPC H Y PG T+ C C+C
Sbjct: 857 DCPCVHNEATYKPGETIRVDCNTCTC 882
Score = 49.7 bits (117), Expect = 8e-05
Identities = 56/220 (25%), Positives = 73/220 (33%), Gaps = 42/220 (19%)
Query: 4556 LRDPTGLSPTLAPLLAS-----EQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG 4610
L PT P PL A E HR L PA Q LC
Sbjct: 237 LDGPTEQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLC---- 292
Query: 4611 ACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQ 4670
CP +C + + +S Q +GG WR E LC C + C G PC +
Sbjct: 293 RCP-TCPCATFVEYSR-QCAHAGGQPRNWRCPE-LCPRTCPLNMQHQEC-GSPCTDT--- 345
Query: 4671 DTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQL------VQDGRCVPISSCR 4724
C+N R Q + C GC CPPG+ + C+P+ C
Sbjct: 346 -------CSNP---------QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCP 389
Query: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
C + +P + C +CTC C CP
Sbjct: 390 C----THGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCP 425
Score = 49.7 bits (117), Expect = 8e-05
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 15/118 (12%)
Query: 1784 RTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVTCPPDWP 1842
R CA G + R + CP+ TC + Q C +PC TC + C
Sbjct: 307 RQCAHAGGQPRNWRCPELCPR------TCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCV 360
Query: 1843 CGSPGCWCPEGQ---VLG--SEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDG 1895
GC+CP G+ VL + C+ QCPC G Y PG C C C G
Sbjct: 361 ---DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGG 415
Score = 48.1 bits (113), Expect = 2e-04
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 3319 YSPCGPPCPRSC-DDLVHCVWRCQ--PGCY--CPPGQVLSSNGAI-CVQPGHCSCLDLLT 3372
Y PCG PC ++C + HC+ GCY CPP Q + + CV C C D
Sbjct: 1171 YQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYD-KD 1227
Query: 3373 GQRHHPGARLARPDGCNHCTCLEGRLNC 3400
G + GAR+ + C C C + C
Sbjct: 1228 GNYYDVGARVPTAENCQSCNCTPSGIQC 1255
Score = 48.1 bits (113), Expect = 2e-04
Identities = 85/344 (24%), Positives = 114/344 (33%), Gaps = 99/344 (28%)
Query: 3479 GPWSPCDMCLGQSHRSRACSRPPT--PEGGRPCPG----NHTQSRPCQENST--QCTD-- 3528
G + P D L +H P P+G PG ++ QS C E S QC
Sbjct: 5394 GCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLP 5453
Query: 3529 CGGGQSLHPCGQPC------PRSCQDLSPGSVCQPGSVGC-QPTCGCPLGQLS----QDG 3577
C PC +P PR+ P +VC + C Q CP GQ S ++G
Sbjct: 5454 CDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEG 5513
Query: 3578 LCVPPAHCR---CQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAG-- 3632
C P CR C Y G+ G+ F PG + PC CTC++G
Sbjct: 5514 DCCPTFRCRPQLCSYNGTFYGV--------GATF-------PGAL---PCHMCTCLSGDT 5555
Query: 3633 ---ILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQS----- 3684
+QCQE D + ++ + C G C + C P Q
Sbjct: 5556 QDPTVQCQE--DACNNTTCPQGFEYKRVAGQCCG-------ECVQTACLTPDGQPVQLNE 5606
Query: 3685 -------RTCSTQVC-----------REAGCPAGRLYRECQPGEGCPFSCAHVTQQV--- 3723
C+ +C + A CP R GC +SC + QV
Sbjct: 5607 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEEDSCQVRIN 5666
Query: 3724 -------GCFSE----GCEEGC------HCPEGTFQHRLACVQE 3750
GC +E CE C QH+ C QE
Sbjct: 5667 TTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQE 5710
Score = 47.4 bits (111), Expect = 4e-04
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Query: 3122 GCHCPSGMLLLN-NVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIA-------- 3172
GC CP+G L + CVP Q+CPC G + PG V CSC G ++
Sbjct: 734 GCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQK 793
Query: 3173 --NCSSWPCAEGEPTWSPWTPWSQCSASC 3199
C++ S TP ++C SC
Sbjct: 794 STGCAAPMVYLDCSNSSAGTPGAECLRSC 822
Score = 43.1 bits (100), Expect = 0.007
Identities = 35/143 (24%), Positives = 54/143 (37%), Gaps = 27/143 (18%)
Query: 3671 RCARPPCPGPARQSRTCS-----------TQVCREAGCPAGRLYRECQPGEGCPFSCAHV 3719
RC PC SR C+ ++C CP ++EC G C +C++
Sbjct: 293 RCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT-CPLNMQHQEC--GSPCTDTCSNP 349
Query: 3720 TQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDE 3779
+ C + C +GC CP G L + C+ L + T G G
Sbjct: 350 QRAQLC-EDHCVDGCFCPPGRSCTVLDDITHSGCLP----LGQCPCTHG--------GRT 396
Query: 3780 LDSGQTLRTSCGNCSCAHGKLSC 3802
G + T+C +C+C+ G C
Sbjct: 397 YSPGTSFNTTCSSCTCSGGLWQC 419
Score = 42.4 bits (98), Expect = 0.012
Identities = 108/477 (22%), Positives = 145/477 (30%), Gaps = 122/477 (25%)
Query: 4361 PCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPAS---RGARAGAPCTRLDGHFRPCLISN 4417
PCP + + S C LV S RG R PC L+ + C
Sbjct: 5287 PCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRG-RLEVPCQSLEAYAELCRARG 5345
Query: 4418 CSED-----------SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPK--- 4463
D +C P + CG C S L GC+CP+
Sbjct: 5346 VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCN---SRNQSPQLEGMAEGCFCPEDQI 5402
Query: 4464 ------GLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGE------ 4511
G+ QA C+ P+ G PG+R C+ C C G
Sbjct: 5403 LFNAHMGICVQACPCVGPD------------GFPKFPGERWVSNCQSCVCDEGSVSVQCK 5450
Query: 4512 -LHCTSQG----CQ--GLLPLSEWSEWSPCGP---CLPPSALAPASRTAL----EEHWLR 4557
L C +QG C G + ++ +PC P C+ + P S E +
Sbjct: 5451 PLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQ 5510
Query: 4558 DPTGLSPTLAPLLASEQHRHRLCLDPAT----GRPWTGA--PHLCTAPLSQQRLCPDPGA 4611
+ PT + R +LC T G + GA H+CT LS P
Sbjct: 5511 EEGDCCPTF-------RCRPQLCSYNGTFYGVGATFPGALPCHMCTC-LSGDTQDPTVQC 5562
Query: 4612 CPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGC---------------REPWAQ 4656
D+C C GF ++ C G C E W
Sbjct: 5563 QEDACN----------NTTCPQGF--EYKRVAGQCCGECVQTACLTPDGQPVQLNETWVN 5610
Query: 4657 ESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGC-----------R 4705
+ CEA+ V L P SC D+ C + GC R
Sbjct: 5611 SHVDNCTVYLCEAEGGVHLL---TPQPASCPDV---SSCRGSLRKTGCCYSCEEDSCQVR 5664
Query: 4706 CPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQE 4762
L G ++ C AS A AQA+Q CTC E V H+E
Sbjct: 5665 INTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQ---HQCTCCQERRV--HEE 5716
Score = 41.2 bits (95), Expect = 0.027
Identities = 29/110 (26%), Positives = 39/110 (35%), Gaps = 15/110 (13%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL---EQDGGCVPI 4114
C+ CP C P C+ + + +GC CP+ + G CV
Sbjct: 5358 CDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEG---MAEGCFCPEDQILFNAHMGICVQA 5414
Query: 4115 GHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLS-------CTAQPCPPP 4157
C C G PG + C +C C G +S C AQ PPP
Sbjct: 5415 --CPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPP 5462
Score = 38.5 bits (88), Expect = 0.17
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 27/112 (24%)
Query: 3531 GGQSLH--PCGQPCPRSCQDLSPGSVC---QPGSVGCQPTCGCPLGQLSQDGL-CVPPAH 3584
GG H PCG PC ++C+ +P C PG GC P C ++D + CV A
Sbjct: 1165 GGCEWHYQPCGAPCLKTCR--NPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQ 1220
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQC 3636
C C + G G+R + E+ C +C C +QC
Sbjct: 1221 CGCYDKDG-------NYYDVGARVPTAEN----------CQSCNCTPSGIQC 1255
Score = 38.1 bits (87), Expect = 0.23
Identities = 54/197 (27%), Positives = 69/197 (35%), Gaps = 30/197 (15%)
Query: 1506 GAIQLCDGVWD-CPDGADEGPGHCPLPSLPTPPASTLPGPSPG---SLDTASSPLASAS- 1560
G +Q DG + CPD G+C TL GP+ +L +++ LA+ +
Sbjct: 232 GNLQKLDGPTEQCPDPLPLPAGNCT--DEEGICHRTLLGPAFAECHALVDSTAYLAACAQ 289
Query: 1561 -----PAPPCGPF---EFRCGSGECTPRGWRCDQ--EEDCADGSDERGCGGPCA-----P 1605
P PC F +C PR WRC + C + CG PC P
Sbjct: 290 DLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNP 349
Query: 1606 HHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDAC---GGLPALGGPNRTGLPCPEY--T 1660
A HCV C R C D C G P G RT P + T
Sbjct: 350 QRAQLCE-DHCVD-GCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTT 406
Query: 1661 CPNGTCIGFQLVCDGQP 1677
C + TC G C P
Sbjct: 407 CSSCTCSGGLWQCQDLP 423
Score = 37.7 bits (86), Expect = 0.30
Identities = 39/168 (23%), Positives = 55/168 (32%), Gaps = 42/168 (25%)
Query: 4596 CTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWA 4655
CTA + + C D G C W C + C GGC W
Sbjct: 1129 CTAVAAYAQACHDAGLCVS------WRTPDTCPLFCDFYNP----------HGGCE--WH 1170
Query: 4656 QESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGC--RCPPGQ-LV 4712
+ C G PC + C N H DL P GC +CPP Q
Sbjct: 1171 YQPC-GAPCLKT----------CRNPSGHCLVDL---------PGLEGCYPKCPPSQPFF 1210
Query: 4713 QDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPH 4760
+ + ++ C C N +++ +CQ+C C + C H
Sbjct: 1211 NEDQMKCVAQCGCYDKDGNY-YDVGARVPTAENCQSCNCTPSGIQCAH 1257
Score = 37.7 bits (86), Expect = 0.30
Identities = 102/416 (24%), Positives = 125/416 (30%), Gaps = 101/416 (24%)
Query: 1501 DGTCLGAIQLCDGVWDCPDGADEG---PGHCPLPSLPTPPASTLPGPSPGSLDTA----- 1552
DGT + + W PD +G P P + P P S+ P P+P
Sbjct: 5239 DGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLML 5298
Query: 1553 SSPLASASPAPPCGPFEFRCGSGECTPR-GWRCDQEEDCAD-------GSDERGCGG--- 1601
S A P GPF C S C R C E A+ SD RG G
Sbjct: 5299 SQVFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLC 5358
Query: 1602 -----------PCAP-HHAPC------------ARGPHCVSPEQLCDG-----VRQCPDG 1632
PC P A C A G C + L + V+ CP
Sbjct: 5359 DLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQACP-- 5416
Query: 1633 SDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQ---LVCDGQ---PDCGRPGQVG 1686
GPD G P G R C C G+ + Q L CD Q P C RPG V
Sbjct: 5417 -CVGPD---GFPKFPG-ERWVSNCQSCVCDEGS-VSVQCKPLPCDAQGQPPPCNRPGFVT 5470
Query: 1687 PSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAA 1746
+ A P P C C +S P G Q + + C T
Sbjct: 5471 VTRPR----AENPCCPETVC--VCNTTTCPQSLPVCPPG----QESICTQEEGDCCPTFR 5520
Query: 1747 CPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDG 1806
C ++ T CH C L G T C +D
Sbjct: 5521 CR-----PQLCSYNGTFYGVGATFPGALPCH-------MCTCLSGDTQD--PTVQCQEDA 5566
Query: 1807 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQ-VLGSEGW 1861
C N TC P ++GQ C C P+GQ V +E W
Sbjct: 5567 CNNTTC----------PQGFEYKRVAGQCC----GECVQTACLTPDGQPVQLNETW 5608
Score = 35.8 bits (81), Expect = 1.1
Identities = 28/118 (23%), Positives = 35/118 (29%), Gaps = 16/118 (13%)
Query: 3099 CAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVV 3158
C G SC S + T GC P L +N T C H G
Sbjct: 779 CTGGKLSCLGASLQKST------GCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFST 832
Query: 3159 RPCENCSCVSGLIANCS-------SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRF 3209
C C GL+++ S PC E T+ P C C R+
Sbjct: 833 HCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYK---PGETIRVDCNTCTCRNRRW 887
Score = 34.7 bits (78), Expect = 2.5
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 3310 NCTAIEGAEY--SPCGPPCPRSCDDLVHCVWRCQP--GCYCPPGQVLSSNGAICVQPGHC 3365
NC + Y C P C + V C P GC CP G L+ GA CV C
Sbjct: 697 NCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGA-CVPAQEC 755
Query: 3366 SCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNC 3400
C G PG + +G C+C G+L+C
Sbjct: 756 PC--YAHGTVLAPG-EVVHDEGA-VCSCTGGKLSC 786
Score = 33.9 bits (76), Expect = 4.3
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 4/74 (5%)
Query: 2297 HWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHH--GESVQMVTTTPIPQMEAR 2354
H P + T+H P SP + T P P + P H G S T TP +
Sbjct: 3496 HTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTST 3555
Query: 2355 TLP--PGMAAVTVV 2366
LP P A +T V
Sbjct: 3556 LLPSSPTSAPITTV 3569
Score = 32.7 bits (73), Expect = 9.6
Identities = 38/166 (22%), Positives = 55/166 (33%), Gaps = 18/166 (10%)
Query: 4525 LSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPA 4584
L W P P L P+ +A + L+ +LAP L SE +
Sbjct: 1709 LGTWRPSQP--PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSEL---------S 1757
Query: 4585 TGRPWTGAPHLCT--APLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREA 4642
T + T P T +PL+ C C+W+ W P SG
Sbjct: 1758 TSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWT---EWFDVDFPTSGVAGGDMETF 1814
Query: 4643 EALCGGGCREPWAQES--CNGGPCPECEAQDTVFTLDCANQCPHSC 4686
E + G + WA +S C PE L C+ + +C
Sbjct: 1815 ENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTC 1860
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 602 bits (1553), Expect = e-171
Identities = 416/1290 (32%), Positives = 579/1290 (44%), Gaps = 131/1290 (10%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLA---GAADSTWAVHLTPGDRCPQPGHCQRVTMG 251
C++W FHY+TFDG + F G C Y+ + GAA + + L P RV M
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT-LSRVLMK 139
Query: 252 PEEVLIQA--GNVSVKGQ--LVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSI 307
+ V+IQ G+V V G L+P QS G+ +Q + + LG+V+ + S+
Sbjct: 140 VDGVVIQLTKGSVLVNGHPVLLPFSQS----GVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
Query: 308 SISVDHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVE 366
+ +D + +T GLCG +NG P + + L + FGN ++ C D V
Sbjct: 196 LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME--FGNLQKMDDPTEQCQDPVP 253
Query: 367 VAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEACLFAYCAG 425
EP + +C +LL G F C A V Y EAC C
Sbjct: 254 ---------------EPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCF- 297
Query: 426 AMAGSGQEGRQQAVCATFASYVQACARRH-IHIRWRKPGFCERLCPGGQLYSDCVSLCPP 484
VC T A Y + C + WR P FC + CP Y +C S C
Sbjct: 298 ----CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 485 SCEAVGQGEEESCREECVSGCECPRGLFWNG---TLCVPAAHCPCYYCRQRYVPGDTVRQ 541
+C Q +C + CV+GC CP G + T CVP + C C Y Y PG T
Sbjct: 354 TCS--NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYST 411
Query: 542 LCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQL 601
C C C GRW C + CP C+V G H+ TFDG+ Y+ G C Y L +
Sbjct: 412 DCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGD--CSYVLTKPCDSSAF 469
Query: 602 LILLEHGAC---DAGSCLHAISVSLE--DTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVR 656
+L E C D+ +CL ++++SL+ T + ++ SG V +N LP I A +++
Sbjct: 470 TVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLP-ISAANVTIF 528
Query: 657 RASSAFLLLRWP-GAQVLWGLSDPVA-YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGD 714
R S+ F++ + G Q+ L + ++ L P+ Q GLCG F Q DDF T +G
Sbjct: 529 RPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGV 588
Query: 715 VETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHR 772
VE + AAF + F+ + CP+ ++ PC+ + +A+ C+ L + F CH
Sbjct: 589 VEATAAAFFNTFKT--QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHA 646
Query: 773 LVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVM--CPG 829
V +Y C+ C C+ DCLC LS+Y CA +G WR+ M CP
Sbjct: 647 AVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPK 706
Query: 830 GQEYR----ECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLG 885
Y C P C C V GC CP G D G+CV S CPC
Sbjct: 707 SMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHR 766
Query: 886 ARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY------APG----ACL 935
G + C C G +C P+ C +V+ PG C
Sbjct: 767 GSMIPNGESVHDSGAICTCTH-GKLSCIGGQAPAPV-CAAPMVFFDCRNATPGDTGAGCQ 824
Query: 936 LTCDSPSANHSCPAGSTDGCVCPPGTVLLDER-CVPPDLCPCRHSGQWYLPNATIQEDCN 994
+C + P GCVCP G V E C+ + CPC H+ Y TI+ CN
Sbjct: 825 KSCHTLDMTCYSPQ-CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCN 883
Query: 995 VCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASG-------L 1047
C C R W CT C G HY+TFDG ++++ G CEY LV+ G
Sbjct: 884 TCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDS 943
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRR 1107
F V +N+PCG +G TC+KA+ + L G + + G+ V V G + YT +R+
Sbjct: 944 FRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGK-VEVIGTDESQEVPYT-----IRQ 997
Query: 1108 AGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
G++L++ T +GL LLWD T + + LSP+F+GRV GLCG+FD A ND +R +
Sbjct: 998 MGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGD 1057
Query: 1168 AELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYE 1227
+SW+LSP CP+ PCT N R WA+ +C L P F CHA V P ++YE
Sbjct: 1058 VLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYE 1117
Query: 1228 WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE----GGQV--- 1280
C+ DAC CDSGGDCEC C+A+A YA C G V WR+ +C L C+ GQ
Sbjct: 1118 ACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWH 1177
Query: 1281 YEACGPTCPPTCHEQHPEPGWHC-QVVACVEGCF--C-PEGTLLHGGACLEPASCP---- 1332
Y+ CG C TC P C + V +EGC+ C PE + A+CP
Sbjct: 1178 YQPCGVPCLRTCR----NPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPL 1233
Query: 1333 ---CEWGRNSFPPGSVL--QKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENG 1387
C S+ PG+V+ K+C +C C E G C AC +C NG
Sbjct: 1234 PPRCHVHGKSYRPGAVVPSDKNCQSCLCTE-------RGVECTYKAEAC-----VCTYNG 1281
Query: 1388 HCVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417
G + + D G G GC + CG
Sbjct: 1282 QRFHPGDVIYHTTD-GTG----GCISARCG 1306
Score = 246 bits (629), Expect = 3e-64
Identities = 180/610 (29%), Positives = 256/610 (41%), Gaps = 64/610 (10%)
Query: 917 CPSQAFCPRELVY--APGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD---ERCVPP 971
CP + CP + Y C TC + + +C GC CP GTVL D CVP
Sbjct: 334 CPQK--CPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPV 391
Query: 972 DLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFT 1031
C C ++G Y P AT DC C C G +W C G C G H+ TFDG +T
Sbjct: 392 SKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYT 451
Query: 1032 YPGACEYLLVREA-SGLFTVSAQNLPCGASGL-TCTKALAVRLEG--TVVHMLRGRAVTV 1087
G C Y+L + S FTV A+ CG + TC K++ + L+G TVV + V +
Sbjct: 452 VHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFL 511
Query: 1088 NGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD--GGTRVLVQLSPQFRGRVAGL 1145
N + P + R + F++ T LGL L ++ +QL+P+ RG+ GL
Sbjct: 512 NQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGL 570
Query: 1146 CGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE-PGDLPHPCTMNTHRAGWARAR 1204
CG+F+ ++D R+ GV+E TA ++++ CP PC+++ +A+
Sbjct: 571 CGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHW 630
Query: 1205 CGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHH 1262
C L F CHA V P +Y C++D C C+ DC LC+A+++Y CA G
Sbjct: 631 CSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDC--LCAALSSYVHACAAKGVQ 688
Query: 1263 VRWRSQELCS---LQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQV-VACVEGCFCPEGT 1318
+ +C+ C Y TC PTC E C V V+GC CP+GT
Sbjct: 689 LGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS-EGDITCSVGFIPVDGCICPKGT 747
Query: 1319 LLHG-GACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACA 1377
L G C++ ++CPC + P G + CTC G+ C G + P CA
Sbjct: 748 FLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGG----QAPAPVCA 803
Query: 1378 EGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDR 1437
C N G+ GC C MTC S C+P +
Sbjct: 804 APMVFFD-----------CRNATPGDTGA---GCQK-SCHTLDMTCYSPQCVPGCV---- 844
Query: 1438 QDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLG--QVTCVPG 1495
CP GL+A +G C+ H + A + +G TC
Sbjct: 845 --------------CPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSR 890
Query: 1496 EVSCVDGTCL 1505
C D CL
Sbjct: 891 MWRCTDDPCL 900
Score = 149 bits (375), Expect = 9e-35
Identities = 123/428 (28%), Positives = 184/428 (42%), Gaps = 37/428 (8%)
Query: 152 SSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPS-ATCASWSGFHYRTFDGRH 210
S AC + + PG+ S G WS + P TC+ G H+ TFDG+
Sbjct: 392 SKCACVYNGAAYAPGATYSTDCTNCTCS--GGRWSCQEVPCPGTCSVLGGAHFSTFDGKQ 449
Query: 211 YHFLGRCTYLLAGAADSTWAVHLTPGDRC---PQPGHCQRVTMGPE----EVLIQAGNVS 263
Y G C+Y+L DS+ L RC + VT+ + V+I+A
Sbjct: 450 YTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEV 509
Query: 264 VKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLD--RTGSISISVDHELWGQTQG 321
Q+ + + + +++ LG+ + L T + + + +L GQT G
Sbjct: 510 FLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCG 569
Query: 322 LCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADV 381
LCG +N DDF G + AA F N+++ + ++ E DP L V
Sbjct: 570 LCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFE-----DPCSL---SV 621
Query: 382 EPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAV 439
E AQ C QL +GPFG+CHA V P Y+ C+F C E + +
Sbjct: 622 EN---EKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTC-------NCERSEDCL 671
Query: 440 CATFASYVQACARRHIHIRWRKPGFCER---LCPGGQLYSDCVSLCPPSCEAVGQGEEE- 495
CA +SYV ACA + + + + G C + CP Y VS C P+C ++ +G+
Sbjct: 672 CAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC 731
Query: 496 SCREECVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWH 554
S V GC CP+G F + T CV A++CPCY+ G++V C C G+
Sbjct: 732 SVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLS 791
Query: 555 CAQALCPA 562
C PA
Sbjct: 792 CIGGQAPA 799
Score = 124 bits (310), Expect = 3e-27
Identities = 124/427 (29%), Positives = 172/427 (40%), Gaps = 73/427 (17%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLL----AGAADSTWAVH--LTPGDRCPQPG--- 243
ATCA + HY TFDG+ Y F G C Y L G DST +T C G
Sbjct: 901 ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960
Query: 244 -HCQRVTMGPEEVLIQAGNVSVKG----QLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
++ +G E+ + G V V G Q VP +++ +G +LV+ +G+V
Sbjct: 961 SKAIKIFLGGFELKLSHGKVEVIGTDESQEVP---------YTIRQMGIYLVVDTDIGLV 1011
Query: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
+ D+ SI I++ E G+ GLCG ++ +DF + FGNSW+L S
Sbjct: 1012 LLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS- 1070
Query: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEA 417
C DA+ C ++ AQ C +L GP F CHA V PA Y+EA
Sbjct: 1071 --CPDALAPKDPC---------TANPFRKSWAQKQC-SILHGPTFAACHAHVEPARYYEA 1118
Query: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLC----PGGQ 473
C+ CA SG G + C A+Y QAC + + WR P C C P GQ
Sbjct: 1119 CVNDACA---CDSG--GDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQ 1173
Query: 474 L---YSDCVSLCPPSCEAVGQGEEESCREEC--VSGC--EC-PRGLFWNGTLCVPAAHCP 525
Y C C +C + C + + GC +C P ++ A CP
Sbjct: 1174 CEWHYQPCGVPCLRTC----RNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCP 1229
Query: 526 -------CYYCRQRYVPGDTV--RQLCNPCVCRDGRWHCAQALCPAECAVG------GDG 570
C+ + Y PG V + C C+C + C C GD
Sbjct: 1230 TPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDV 1289
Query: 571 HYLTFDG 577
Y T DG
Sbjct: 1290 IYHTTDG 1296
Score = 82.0 bits (201), Expect = 1e-14
Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 6/101 (5%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD---GGCVPI 4114
C CP M+ C + C CS+ + C+D C GC CP+G++ D GCVP+
Sbjct: 334 CPQKCPNNMQYHECRSPCADTCSNQEHSRACEDH--CVAGCFCPEGTVLDDIGQTGCVPV 391
Query: 4115 GHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
C C G ++APG+ + C NC+C G+ SC PCP
Sbjct: 392 SKCACV-YNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCP 431
Score = 79.3 bits (194), Expect = 9e-14
Identities = 40/108 (37%), Positives = 48/108 (44%), Gaps = 10/108 (9%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHN---AS 2938
C +CP NM Q H+ PC C Q C C GC CP G L +
Sbjct: 334 CPQKCPNNM------QYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTG 387
Query: 2939 CLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
C+P S+C C +G YA GA D C NCTC G+ +C CP C
Sbjct: 388 CVPVSKCACVYNGAAYAPGATYSTD-CTNCTCSGGRWSCQEVPCPGTC 434
Score = 72.8 bits (177), Expect = 8e-12
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Query: 2634 PCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHD---TRCLPLSECPCLVGEELKWPGVSF 2690
PC +C + + +R+C HCV GC CP G +L D T C+P+S+C C+ PG ++
Sbjct: 350 PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 2691 LLGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G CQ CP C
Sbjct: 410 ST-DCTNCTCSGGRWSCQEVPCPGTC 434
Score = 72.0 bits (175), Expect = 1e-11
Identities = 46/169 (27%), Positives = 65/169 (38%), Gaps = 24/169 (14%)
Query: 4356 GCYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLI 4415
G Y C ++ + + C C L + Y Q CT G +
Sbjct: 285 GSYLEACRQDLCFCEDTDLLSCVCHTLAE--YSRQ------------CTHAGGLPQDWRG 330
Query: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKG-LLEQAG--GC 4472
+ C ++H C SPCA C+ + C+D C GC+CP+G +L+ G GC
Sbjct: 331 PDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACED--HCVAGCFCPEGTVLDDIGQTGC 388
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521
+P +C C + AA APG C C C G C C G
Sbjct: 389 VPVSKCACVYNGAA-----YAPGATYSTDCTNCTCSGGRWSCQEVPCPG 432
Score = 71.2 bits (173), Expect = 2e-11
Identities = 56/223 (25%), Positives = 77/223 (34%), Gaps = 27/223 (12%)
Query: 4813 QPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLLHN-GTCVPP 4869
+P CP ++C C L G I P GC CP G L + G CV
Sbjct: 699 KPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQA 758
Query: 4870 TACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGET- 4928
+ CPC + +P G + + C C G SC P
Sbjct: 759 SNCPCYH-------------RGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAP 805
Query: 4929 -----WQQVAPGELGL-CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPED 4982
+ PG+ G C+++C ++ T C GCVC G G C+ +
Sbjct: 806 MVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQC----VPGCVCPDGLVADGEGGCITAE 861
Query: 4983 HCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
C C H + G + C +C C S CT TCA
Sbjct: 862 DCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCA 904
Score = 68.2 bits (165), Expect = 2e-10
Identities = 55/198 (27%), Positives = 75/198 (37%), Gaps = 38/198 (19%)
Query: 4338 MAKADPTCNSTFLHLDTQGCYSGPCPEE---CVWSSWSSWTRCSCRVLVQQRYRHQGPAS 4394
+++ D TC+ F+ +D C G ++ CV +S C C H+G
Sbjct: 724 LSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQAS-----NCPCY--------HRGSMI 770
Query: 4395 RGARA----GAPCTRLDGHFRPCLISNCSEDSCTPPFEFHAC--------GSPCAGLCAT 4442
+ GA CT G C+ C P F C G+ C C
Sbjct: 771 PNGESVHDSGAICTCTHGKLS-CIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSC-- 827
Query: 4443 HLSHQLCQDLPPCQPGCYCPKGLL-EQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLG 4501
H C P C PGC CP GL+ + GGCI E+C C H A + G +++G
Sbjct: 828 HTLDMTCYS-PQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEA-----SYRAGQTIRVG 881
Query: 4502 CKECECRRGELHCTSQGC 4519
C C C CT C
Sbjct: 882 CNTCTCDSRMWRCTDDPC 899
Score = 67.8 bits (164), Expect = 3e-10
Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Query: 3318 EYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQVLSSNGAI-CVQPGHCSCLDLLTG 3373
+Y C PC +C + H C C GC+CP G VL G CV C+C+ G
Sbjct: 343 QYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACV--YNG 400
Query: 3374 QRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
+ PGA + C +CTC GR +C ++PCP
Sbjct: 401 AAYAPGATYSTD--CTNCTCSGGRWSCQEVPCP 431
Score = 66.6 bits (161), Expect = 6e-10
Identities = 49/157 (31%), Positives = 64/157 (40%), Gaps = 26/157 (16%)
Query: 1765 PC--RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC- 1821
PC RG+M + S + G C G L P P C+ ++F C
Sbjct: 762 PCYHRGSMIPNGE--SVHDSGAICTCTHGKLSCIGGQAPAP-------VCAAPMVFFDCR 812
Query: 1822 --------APCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
A C +C + +TC P PGC CP+G V EG C+ CPC+ +
Sbjct: 813 NATPGDTGAGCQKSCHTLD--MTCYS--PQCVPGCVCPDGLVADGEGGCITAEDCPCVHN 868
Query: 1874 GARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
A Y GQ I+ C C C D R RC +P C C
Sbjct: 869 EASYRAGQTIRVGCNTCTC-DSRMWRCTDDP-CLATC 903
Score = 66.2 bits (160), Expect = 8e-10
Identities = 44/134 (32%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
Query: 1766 CRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APC 1824
C T CH+ R C G R CPQ CPN + + C +PC
Sbjct: 298 CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQK-CPN-----NMQYHECRSPC 351
Query: 1825 PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGW--CVWPRQCPCLVDGARYWPGQR 1882
TC + C G C+CPEG VL G CV +C C+ +GA Y PG
Sbjct: 352 ADTCSNQEHSRACEDHCVAG---CFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGAT 408
Query: 1883 IKADCQLCICQDGR 1896
DC C C GR
Sbjct: 409 YSTDCTNCTCSGGR 422
Score = 65.9 bits (159), Expect = 1e-09
Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDC 3142
P CP + Q+ +C A +C+ R C GC CP G +L + CVP C
Sbjct: 335 PQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKC 394
Query: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
C + G Y PG+T C NC+C SG +C PC
Sbjct: 395 ACVYNGAAYAPGATYSTDCTNCTC-SGGRWSCQEVPC 430
Score = 61.6 bits (148), Expect = 2e-08
Identities = 67/284 (23%), Positives = 90/284 (31%), Gaps = 27/284 (9%)
Query: 3981 HWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGG 4040
HWC + A + F A PG + + C+ RS C +
Sbjct: 629 HWCSQLTDA--DGPFGRCHAAVKPGTYYSNCMFDTCNCE-------RSEDCLCAALSSYV 679
Query: 4041 APCAGERHQARLCNPMPCE---AGCPAGMEVVTCANRCPRRCSDLQEG-IVCQDDQVCQK 4096
CA + Q C CP M + C C L EG I C +
Sbjct: 680 HACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVD 739
Query: 4097 GCRCPKGS-LEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
GC CPKG+ L+ G CV +C C +G G D+ C+C G+LSC P
Sbjct: 740 GCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGAICTCTHGKLSCIGGQAP 798
Query: 4156 PPTHCA---------WSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPC 4206
P A + + C SC G P+ +
Sbjct: 799 APVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCI 858
Query: 4207 PQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTEC 4250
CP C+ S G + G C C+C C D C
Sbjct: 859 TAEDCP--CVHNEASYRAGQTIRVG-CNTCTCDSRMWRCTDDPC 899
Score = 60.5 bits (145), Expect = 4e-08
Identities = 70/301 (23%), Positives = 98/301 (32%), Gaps = 107/301 (35%)
Query: 3527 TDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPT--CGCPLGQLSQD-GLCVPPA 3583
T C + H C +C+ LS G + SVG P C CP G D G CV +
Sbjct: 702 TTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVGFIPVDGCICPKGTFLDDTGKCVQAS 759
Query: 3584 HCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
+C C ++ GS + ES+ + CTC G L
Sbjct: 760 NCPCYHR--------------GSMIPNGESVHDSGAI------CTCTHGKL--------- 790
Query: 3644 DPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLY 3703
SC GG+ P P C A ++
Sbjct: 791 ----------------SCIGGQ-----------APAPV---------------CAAPMVF 808
Query: 3704 RECQ------PGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQH-RLACV--QECPCV 3754
+C+ G GC SC T + C+S C GC CP+G C+ ++CPCV
Sbjct: 809 FDCRNATPGDTGAGCQKSCH--TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCV 866
Query: 3755 LTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGF 3814
+ +GQT+R C C+C C+ D C +
Sbjct: 867 HNEASYR--------------------AGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVY 906
Query: 3815 G 3815
G
Sbjct: 907 G 907
Score = 59.3 bits (142), Expect = 1e-07
Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 18/111 (16%)
Query: 4815 CPE-CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHN---GTCVPPT 4870
CP+ CP C + C C + + C ++ C GC CP G +L + CVP +
Sbjct: 334 CPQKCPNNMQYHECRSPCADTCSNQEHSRAC-EDHCVAGCFCPEGTVLDDIGQTGCVPVS 392
Query: 4871 ACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
C C + + PG + +CT C C GG +SC V C
Sbjct: 393 KCACVYNGAAYA-------------PGATYSTDCTNCTCSGGRWSCQEVPC 430
Score = 58.9 bits (141), Expect = 1e-07
Identities = 48/187 (25%), Positives = 62/187 (33%), Gaps = 14/187 (7%)
Query: 2806 SPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDT 2865
S GD +C + C P G S C G + G S
Sbjct: 725 SEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHD---SGA 781
Query: 2866 TCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCH--QEGGPCPRLCLTQGPGIECTGF-- 2921
C H + Q C M+F G C + C T ++ T +
Sbjct: 782 ICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHT----LDMTCYSP 837
Query: 2922 -CAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTS 2979
C PGC CP GL C+ CPC + Y +G R+ CN CTC S CT
Sbjct: 838 QCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRV-GCNTCTCDSRMWRCTD 896
Query: 2980 ERCPVAC 2986
+ C C
Sbjct: 897 DPCLATC 903
Score = 57.8 bits (138), Expect = 3e-07
Identities = 42/141 (29%), Positives = 48/141 (34%), Gaps = 40/141 (28%)
Query: 3521 ENSTQCTDCGG-----------------GQSLHPCGQPCPRSCQDLSPGSVCQPGSV-GC 3562
E S QCT GG H C PC +C + C+ V GC
Sbjct: 313 EYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGC 372
Query: 3563 QPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTG 3622
G L + Q G CVP + C C Y A PG +
Sbjct: 373 FCPEGTVLDDIGQTG-CVPVSKCACVYNGAAYA--------------------PGATYST 411
Query: 3623 PCDNCTCVAGILQCQEVPDCP 3643
C NCTC G CQEVP CP
Sbjct: 412 DCTNCTCSGGRWSCQEVP-CP 431
Score = 57.4 bits (137), Expect = 4e-07
Identities = 39/117 (33%), Positives = 47/117 (40%), Gaps = 11/117 (9%)
Query: 3291 CEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW--RCQPGCYCPP 3348
C G +A VC A P +C A G C +SC L + +C PGC CP
Sbjct: 792 CIGGQAPAPVCAA-PMVFFDC---RNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPD 847
Query: 3349 GQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
G V G C+ C C+ R R+ GCN CTC CTD PC
Sbjct: 848 GLVADGEGG-CITAEDCPCVHNEASYRAGQTIRV----GCNTCTCDSRMWRCTDDPC 899
Score = 55.5 bits (132), Expect = 1e-06
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 17/122 (13%)
Query: 4648 GGCREPWAQESCNGGP--CPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
GG + W GP CP+ + + + +C + C +C++ C + C GC
Sbjct: 322 GGLPQDWR------GPDFCPQ-KCPNNMQYHECRSPCADTCSNQEHSRAC-EDHCVAGCF 373
Query: 4706 CPPGQLVQD---GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQE 4762
CP G ++ D CVP+S C C A AP DC NCTC C
Sbjct: 374 CPEGTVLDDIGQTGCVPVSKCACVYNGA----AYAPGATYSTDCTNCTCSGGRWSCQEVP 429
Query: 4763 CP 4764
CP
Sbjct: 430 CP 431
Score = 53.1 bits (126), Expect = 7e-06
Identities = 41/129 (31%), Positives = 49/129 (37%), Gaps = 21/129 (16%)
Query: 4647 GGGCREPWAQESCNGG--PCPECEAQDTVFTLDCANQ--------CPHSCADLWDRVQCL 4696
G C + SC GG P P C A F DC N C SC L + C
Sbjct: 780 GAICTCTHGKLSCIGGQAPAPVCAAPMVFF--DCRNATPGDTGAGCQKSCHTL--DMTCY 835
Query: 4697 QGPCRPGCRCPPGQLVQDGR--CVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNE 4754
C PGC CP G LV DG C+ C C A+ Q +++ C CTC +
Sbjct: 836 SPQCVPGCVCPDG-LVADGEGGCITAEDCPCVHNEAS----YRAGQTIRVGCNTCTCDSR 890
Query: 4755 SLVCPHQEC 4763
C C
Sbjct: 891 MWRCTDDPC 899
Score = 51.6 bits (122), Expect = 2e-05
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 5/88 (5%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGP--CVPEDHCECWHLGRPHLPGS 4997
C TC ++ C +GC C G G CVP C C + G + PG+
Sbjct: 351 CADTCSNQEHSRA---CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGA 407
Query: 4998 EWQEACESCLCLSGRPVCTQHCSPLTCA 5025
+ C +C C GR C + P TC+
Sbjct: 408 TYSTDCTNCTCSGGRWSCQEVPCPGTCS 435
Score = 51.6 bits (122), Expect = 2e-05
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 3119 CHPGCHCPSGMLLLNNV-CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW 3177
C PGC CP G++ C+ +DCPC H Y G T+ C C+C S + C+
Sbjct: 839 CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRM-WRCTDD 897
Query: 3178 PC 3179
PC
Sbjct: 898 PC 899
Score = 51.2 bits (121), Expect = 3e-05
Identities = 30/132 (22%), Positives = 45/132 (34%), Gaps = 10/132 (7%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEW 4999
C+ TC ++ + GC+C G F G CV +C C+H G G
Sbjct: 717 CQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV 776
Query: 5000 QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTEL 5059
++ C C G+ C +P + + CR P + CQ
Sbjct: 777 HDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFD-------CRNATPGDTGAGCQKSCHT 829
Query: 5060 RNFTKGTCYLDQ 5071
+ TCY Q
Sbjct: 830 LDM---TCYSPQ 838
Score = 50.8 bits (120), Expect = 3e-05
Identities = 56/231 (24%), Positives = 80/231 (34%), Gaps = 37/231 (16%)
Query: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQP--------CAPCPLT 1827
C+ ++ CAAL +H+ K G + C+ + P + C T
Sbjct: 662 CNCERSEDCLCAALSSYVHACA-AKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPT 720
Query: 1828 CDDIS-GQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD 1886
C +S G +TC + GC CP+G L G CV CPC G+ G+ +
Sbjct: 721 CRSLSEGDITCSVGF-IPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDS 779
Query: 1887 CQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRG 1946
+C C G+ + C +P C P F N P G
Sbjct: 780 GAICTCTHGK-----------LSC-IGGQAPAPVCAAP-------MVFFDCRNATPGDTG 820
Query: 1947 RQC-RGIHRKARRCQTEPC-EGCEHQGQVHRVGERWHGG--PCRVCQCLHN 1993
C + H C + C GC + GE GG C C+HN
Sbjct: 821 AGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE---GGCITAEDCPCVHN 868
Score = 49.3 bits (116), Expect = 1e-04
Identities = 33/116 (28%), Positives = 42/116 (36%), Gaps = 28/116 (24%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF-----QHRLACVQEC 3751
CP Y EC+ C +C++ C + C GC CPEGT Q V +C
Sbjct: 338 CPNNMQYHECR--SPCADTCSNQEHSRAC-EDHCVAGCFCPEGTVLDDIGQTGCVPVSKC 394
Query: 3752 PCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
CV G G T T C NC+C+ G+ SC C
Sbjct: 395 ACVYN--------------------GAAYAPGATYSTDCTNCTCSGGRWSCQEVPC 430
Score = 48.5 bits (114), Expect = 2e-04
Identities = 42/151 (27%), Positives = 55/151 (36%), Gaps = 41/151 (27%)
Query: 3289 DYCEGPRAQGEVCQALPCPVTNCTA----IEGAEYSPCGPP---CPRSCDDLVHCVWRCQ 3341
D C R++ +C AL V C A + G C P CP+S H V CQ
Sbjct: 660 DTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYH-VSTCQ 718
Query: 3342 P--------------------GCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGAR 3381
P GC CP G L G CVQ +C C +H G+
Sbjct: 719 PTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGK-CVQASNCPC--------YHRGSM 769
Query: 3382 LARPDGCNH----CTCLEGRLNCTDLPCPVP 3408
+ + + CTC G+L+C P P
Sbjct: 770 IPNGESVHDSGAICTCTHGKLSCIGGQAPAP 800
Score = 48.5 bits (114), Expect = 2e-04
Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 21/136 (15%)
Query: 3122 GCHCPSGMLLLNN-VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
GC CP G L + CV +CPC H G + P G +V C+C G ++ C
Sbjct: 740 GCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLS------CI 793
Query: 3181 EGE---PTWSPWTPWSQC--------SASCGPARCHRHRFCARSPSAVPSTVAPLPLPAT 3229
G+ P + + C A C + CH SP VP V P L A
Sbjct: 794 GGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKS-CHTLDMTCYSPQCVPGCVCPDGLVAD 852
Query: 3230 PTPLCSGPEAEEEPCL 3245
C AE+ PC+
Sbjct: 853 GEGGCI--TAEDCPCV 866
Score = 48.1 bits (113), Expect = 2e-04
Identities = 73/311 (23%), Positives = 104/311 (33%), Gaps = 54/311 (17%)
Query: 3045 EWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGP 3103
EW + PC VPC RN R + GL+ C P P D+ + C
Sbjct: 1175 EWH-YQPCGVPCLRTCRNPRGDCLRDVW-----GLEGCYPKCPPEAPIFDEDKMQCV--- 1225
Query: 3104 ASCAELSAPRGTN---QTCHPGCHCPSGMLLLNNVCVP--------TQDCPCAHEGHLYP 3152
A+C P + ++ PG PS + +C + C C + G +
Sbjct: 1226 ATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFH 1285
Query: 3153 PGSTVVRPCENCS-CVSGLIANCSS--------WPCAEGEP----TWSPWTPWSQCSASC 3199
PG + + C+S A C + +PC+ P T+S TP S++
Sbjct: 1286 PGDVIYHTTDGTGGCIS---ARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTH 1342
Query: 3200 GPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWG 3259
P+ SA P+T P PT S P E CL W
Sbjct: 1343 TPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCL------------WS 1390
Query: 3260 PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEY 3319
PW SR G + G CE PR+ C+A P A+ +
Sbjct: 1391 PWMDVSRPGRGTDSGDFDTLENLRAHGY-RVCESPRS--VECRAEDAPGVPLRAL--GQR 1445
Query: 3320 SPCGPPCPRSC 3330
C P +C
Sbjct: 1446 VQCSPDVGLTC 1456
Score = 47.4 bits (111), Expect = 4e-04
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 19/97 (19%)
Query: 3319 YSPCGPPCPRSC----DDLVHCVWRCQPGCY--CPP-GQVLSSNGAICVQ-------PGH 3364
Y PCG PC R+C D + VW + GCY CPP + + CV P
Sbjct: 1178 YQPCGVPCLRTCRNPRGDCLRDVWGLE-GCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR 1236
Query: 3365 CSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCT 3401
C + G+ + PGA + C C C E + CT
Sbjct: 1237 CH----VHGKSYRPGAVVPSDKNCQSCLCTERGVECT 1269
Score = 46.6 bits (109), Expect = 6e-04
Identities = 75/308 (24%), Positives = 101/308 (32%), Gaps = 63/308 (20%)
Query: 4120 TDAQGHSWAPGSQHQDACNN--CSCQAG---QLSCTAQP--------------------C 4154
T A H+ +++ +AC N C+C +G + CTA C
Sbjct: 1102 TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSIC 1161
Query: 4155 P-------PPTHCAWSHWSAWSPCSHSC-GPRGQQSRFRSSTSGSW------APECREEQ 4200
P P C W + PC +C PRG R G + AP E++
Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDK 1221
Query: 4201 SQS-QPCPQPSCPPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVIC----EDTECAVPE 4254
Q CP P PP C + G R CQ C CT GV C E C
Sbjct: 1222 MQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTY-N 1280
Query: 4255 AWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPC-----LGPDTQTRQQPCPGLLE 4309
+ G G + R R PC + P T + P P ++
Sbjct: 1281 GQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTP-PLVVS 1339
Query: 4310 ACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGP-CPEECVW 4368
+ GP S GP S + P + T L T P C E+C+W
Sbjct: 1340 STHTPSNGPSSAHTGP----PSSAWPTTAGTSPRT------RLPTASASLPPVCGEKCLW 1389
Query: 4369 SSWSSWTR 4376
S W +R
Sbjct: 1390 SPWMDVSR 1397
Score = 46.2 bits (108), Expect = 8e-04
Identities = 45/197 (22%), Positives = 72/197 (36%), Gaps = 41/197 (20%)
Query: 2531 PLPGGSCPRDRFRSQS----------CFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQR 2580
P+ G CP+ F + C+ + + ++ ++ C+ + G +
Sbjct: 737 PVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHG------KL 790
Query: 2581 SCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCL 2640
SC+ G AP P + AP C T + G CQK +C
Sbjct: 791 SCI-----GGQAPAPVCA---APMVFFDCRNATPGDTGAG------CQKSC-HTLDMTCY 835
Query: 2641 DPKANRSCSGHCVEGCRCPPGLLLH-DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCV 2699
P+ CV GC CP GL+ + C+ +CPC+ E G + +G C+ C
Sbjct: 836 SPQ--------CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVG-CNTCT 886
Query: 2700 CEKGELLCQPGGCPLPC 2716
C+ C C C
Sbjct: 887 CDSRMWRCTDDPCLATC 903
Score = 45.8 bits (107), Expect = 0.001
Identities = 63/247 (25%), Positives = 79/247 (31%), Gaps = 71/247 (28%)
Query: 3697 CPAGRLYR----ECQPGEGC-PFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA-CVQ- 3749
CP Y CQP C S +T VG +GC CP+GTF CVQ
Sbjct: 704 CPKSMTYHYHVSTCQPT--CRSLSEGDITCSVGFIPV---DGCICPKGTFLDDTGKCVQA 758
Query: 3750 -ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC------ 3802
CPC G + +G+++ S C+C HGKLSC
Sbjct: 759 SNCPCYHR--------------------GSMIPNGESVHDSGAICTCTHGKLSCIGGQAP 798
Query: 3803 --------SLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGP 3854
DC A P C +SC L S QCV GC
Sbjct: 799 APVCAAPMVFFDCRNAT----PGDTGAGCQKSCHTLDMTCYSPQCV--------PGC--- 843
Query: 3855 RQDLECPSPDCPGAEGSTVE----PVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRL 3910
CP EG + P + + +CT +R WR
Sbjct: 844 ----VCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSR-MWRCTDDP 898
Query: 3911 CLANCTM 3917
CLA C +
Sbjct: 899 CLATCAV 905
Score = 44.7 bits (104), Expect = 0.002
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Query: 2632 VPPCPPSCLD-PKANRSCSGHC--VEGCRCPPGLLLHDT-RCLPLSECPCLVGEELKWPG 2687
V C P+C + + +CS V+GC CP G L DT +C+ S CPC + P
Sbjct: 714 VSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSM-IPN 772
Query: 2688 VSFLLGNCSQCVCEKGELLCQPGGCPLP 2715
+ + + C C G+L C G P P
Sbjct: 773 GESVHDSGAICTCTHGKLSCIGGQAPAP 800
Score = 42.7 bits (99), Expect = 0.009
Identities = 83/338 (24%), Positives = 110/338 (32%), Gaps = 59/338 (17%)
Query: 3178 PCAEGEPTWSPWTPWSQCSASCGP--ARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235
PC P W QCS GP A CH H AR A + C+
Sbjct: 1080 PCT-ANPFRKSWAQ-KQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCT 1137
Query: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG-----GGLRSRTRACDQPPPQGLGDY 3290
A Q C G W S C C G + C P +
Sbjct: 1138 AVAA-----YAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRT---- 1188
Query: 3291 CEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQ-----PGCY 3345
C PR C + + +EG Y C P P +D + CV C P C+
Sbjct: 1189 CRNPRGD--------C-LRDVWGLEGC-YPKCPPEAPIFDEDKMQCVATCPTPPLPPRCH 1238
Query: 3346 CP-----PGQVLSSN----GAICVQPG-HCS-----CLDLLTGQRHHPGARLAR----PD 3386
PG V+ S+ +C + G C+ C+ GQR HPG +
Sbjct: 1239 VHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTG 1298
Query: 3387 GCNHCTC-LEGRLNCTDLPCPVPGGWCPWSEWTMCSQP-CRGQTRSRSRACACPTPQHGG 3444
GC C G + PC P P + ++ + P T + S P+ H G
Sbjct: 1299 GCISARCGANGTIERRVYPCS-PTTPVPPTTFSFSTPPLVVSSTHTPSNG---PSSAHTG 1354
Query: 3445 APCTGEAGEAG-AQHQREACPSYATCPVDGAWGPWGPW 3481
P + AG + R S + PV G W PW
Sbjct: 1355 PPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPW 1392
Score = 34.7 bits (78), Expect = 2.5
Identities = 102/422 (24%), Positives = 128/422 (30%), Gaps = 95/422 (22%)
Query: 4289 SPPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSCGPGLASR--------------SGSC 4334
SP C PD + PC SW CS GP A+ + +C
Sbjct: 1068 SPSC--PDALAPKDPCTANPFRKSWAQ-KQCSILHGPTFAACHAHVEPARYYEACVNDAC 1124
Query: 4335 PCLMAKADPTCNSTFLHLDTQGCYS-GPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPA 4393
C + D C T + Q C+ G C SW S L Y +G
Sbjct: 1125 AC-DSGGDCECFCTAVAAYAQACHEVGLCV---------SWRTPSICPLFCDYYNPEGQC 1174
Query: 4394 SRGAR-AGAPCTRLDGHFR-PCLISNCSEDSCTP--PFE---FHACGSPCAGLCATHLSH 4446
+ G PC R + R CL + C P P E F C C T
Sbjct: 1175 EWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPT---- 1230
Query: 4447 QLCQDLPPCQPGCYCPKGLLEQAGGCIPPEE----CNCWH-----TSAAGAGMTLAPGDR 4497
PP P C+ G + G +P ++ C C T A A + G R
Sbjct: 1231 ------PPLPPRCHV-HGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQR 1283
Query: 4498 LQLGCKECECRRGELHCTSQGC--QGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHW 4555
G G C S C G + + PC P P
Sbjct: 1284 FHPGDVIYHTTDGTGGCISARCGANGTIERRVY----PCSPTTPVP-------------- 1325
Query: 4556 LRDPTGLSPTLAPLLASEQHRHRLCLDPA-TGRPWTGAPHLCTAPLSQQRLCPD-----P 4609
PT S + PL+ S H A TG P + P TA S + P P
Sbjct: 1326 ---PTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWP--TTAGTSPRTRLPTASASLP 1380
Query: 4610 GACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEA 4669
C + C LW PW P G + E L G R C EC A
Sbjct: 1381 PVCGEKC---LWSPWMDVSRPGRGTDSGDFDTLENLRAHGYR------VCESPRSVECRA 1431
Query: 4670 QD 4671
+D
Sbjct: 1432 ED 1433
Score = 34.7 bits (78), Expect = 2.5
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 15/101 (14%)
Query: 2902 GGPCPRLCLTQGPGIECTG--FCAPGC--TCPPGLFLHNAS---CLPRSQCP-----CQL 2949
G PC R C + P +C + GC CPP + + C+ P C +
Sbjct: 1182 GVPCLRTC--RNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHV 1239
Query: 2950 HGQLYASGAMARLD-SCNNCTCVSGKMACTSERCPVACGWS 2989
HG+ Y GA+ D +C +C C + CT + C ++
Sbjct: 1240 HGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYN 1280
Score = 33.9 bits (76), Expect = 4.3
Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 23/107 (21%)
Query: 3537 PCGQPCPRSCQDLSPGSVCQP---GSVGCQPTCGCPLGQLSQDGL-CV-----PPAHCRC 3587
PCG PC R+C+ +P C G GC P C +D + CV PP RC
Sbjct: 1180 PCGVPCLRTCR--NPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRC 1237
Query: 3588 -----QYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTC 3629
Y+PGA+ +P +++ S E G T + C C
Sbjct: 1238 HVHGKSYRPGAV-VPSDKN------CQSCLCTERGVECTYKAEACVC 1277
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 598 bits (1543), Expect = e-170
Identities = 405/1262 (32%), Positives = 574/1262 (45%), Gaps = 143/1262 (11%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAG---AADSTWAVHLTPGDRCPQPGHCQRVTMG 251
C++W FHY+TFDG + F G C Y+ + AA + V L G +P RV +
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPV-VTRVVIK 791
Query: 252 PEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISV 311
+ ++++A N SV E + GL ++ GD++ +S L + + S + +
Sbjct: 792 AQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLEL 851
Query: 312 DHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQG 370
D + QT GLCG +NG P ++F L L FGN +L G C D
Sbjct: 852 DPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGPTEQCPD------- 902
Query: 371 CDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEACLFAYCAGAMAG 429
PL L P + + +CH+ L GP F +CHA V Y AC C
Sbjct: 903 --PLPL------PAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP 954
Query: 430 SGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEA 488
CATF Y + CA R WR P C R CP + +C S C +C
Sbjct: 955 ----------CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCS- 1003
Query: 489 VGQGEEESCREECVSGCECPRG--------LFWNGTLCVPAAHCPCYYCRQRYVPGDTVR 540
+ C + CV GC CP G + +G C+P CPC + + Y PG +
Sbjct: 1004 -NPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTSFN 1060
Query: 541 QLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQ 600
C+ C C G W C CP C+V G H T+D + Y G C Y L +
Sbjct: 1061 TTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGD--CSYVLSKKCADSS 1118
Query: 601 LLILLEHGAC---DAGSCLHAISVSLE--DTHIQLRDSGAVLVNGQDVGLPWIGAEGLSV 655
+L E C D +CL A+++SL+ DT I+++ G V +N LP + A +++
Sbjct: 1119 FTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLP-LSAANITL 1177
Query: 656 RRASSAFLLLRWP-GAQVLWGLSDPV-AYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAG 713
SS F++++ G Q+L L + ++ LDP H Q+ GLCG F QNQ DDF +G
Sbjct: 1178 FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSG 1237
Query: 714 DVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILH--SSVFQECH 771
VE + AAFA+ ++ + C + ++ PC+ + +A C+ L +S F CH
Sbjct: 1238 VVEATGAAFANTWKA--QAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCH 1295
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVM--CP 828
+++ +PF+ C+ C C+ DCLC LS+Y CA +G WR+ M CP
Sbjct: 1296 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 1355
Query: 829 GGQEYRECAPACGQHC-GKPE---DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQL 884
Q Y AC C G E C V GC CP G + G CVP CPC
Sbjct: 1356 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 1415
Query: 885 GARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY---------APGA-C 934
APG E C C G +C C +VY PGA C
Sbjct: 1416 HGTVLAPGEVVHDEGAVCSCTG-GKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 1474
Query: 935 LLTCDSPSANHSCPAGS-----TDGCVCPPGTVLLDER-CVPPDLCPCRHSGQWYLPNAT 988
L +C H+ G GCVCPPG V C+ + CPC H+ Y P T
Sbjct: 1475 LRSC------HTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGET 1528
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVRE----- 1043
I+ DCN C CR R+W C+ + G C A G H++TFDG +++ G+CEY+L ++
Sbjct: 1529 IRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDN 1588
Query: 1044 -ASGLFTVSAQNLPCGASGLTCTKAL----------AVRLEGTVVHMLRGRAVTVNGVSV 1092
G F + +N+PCG +G TC+KA+ AV + R +V
Sbjct: 1589 TTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQR 1648
Query: 1093 TPP--------------KVYTGPG----LSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQL 1134
PP V GPG +R G+FL++ TH G+ + WD T V ++L
Sbjct: 1649 LPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRL 1707
Query: 1135 SPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMN 1194
++GRV GLCG+FD +A ND +R + A +SW+LSP CP+ PCT N
Sbjct: 1708 HQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTAN 1767
Query: 1195 THRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYAD 1254
R WA+ +C L P F C ++V ++YE C+ DAC CDSGGDCEC C+A+A YA
Sbjct: 1768 PFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQ 1827
Query: 1255 ECARHGHHVRWRSQELCSLQCE-----GG--QVYEACGPTCPPTCHEQHPEPGWHCQV-V 1306
C G V WR+ + C L C+ GG Y+ CG C TC P HC V +
Sbjct: 1828 ACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCR----NPSGHCLVDL 1883
Query: 1307 ACVEGCF--CPEGTLLHGGACLE-PASCPC-EWGRNSFPPGSVL--QKDCGNCTCQEGQW 1360
+EGC+ CP ++ A C C + N + G+ + ++C +C C
Sbjct: 1884 PGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGI 1943
Query: 1361 HC 1362
C
Sbjct: 1944 QC 1945
Score = 259 bits (662), Expect = 5e-68
Identities = 258/983 (26%), Positives = 373/983 (37%), Gaps = 205/983 (20%)
Query: 558 ALCPAE----CAVGGDGHYLTFDGRSYSFWG------GQGCRYSLVQDYVKGQLLILLEH 607
AL PA C+ GD HY TFDG + F G + CR + +D+ + L
Sbjct: 723 ALNPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCR-AAYEDFN-----VQLRR 776
Query: 608 GACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRW 667
G + + + + + ++ +G+VL+NGQ LP+ GL V ++ +
Sbjct: 777 GLVGSRPVVTRVVIKAQGLVLEA-SNGSVLINGQREELPY-SRTGLLVEQSGDYIKVSIR 834
Query: 668 PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQ-DDFLTPAGDVETSIAAFASKF 726
LW D A + LDP++A+Q GLCG F ++F A + + F +
Sbjct: 835 LVLTFLWNGEDS-ALLELDPKYANQTCGLCGDFNGLPAFNEFY--AHNARLTPLQFGNLQ 891
Query: 727 QVAGKG-RCPSEDSALLSPCTTHSQRHAFAEAAC-AILHSSVFQECHRLVDKEPFYLRCL 784
++ G +CP CT E C L F ECH LVD
Sbjct: 892 KLDGPTEQCPDPLPLPAGNCTDE-------EGICHRTLLGPAFAECHALVDS-------- 936
Query: 785 AAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEY-RECAPACGQH 843
+AY CAQ+ P CP C EY R+CA A
Sbjct: 937 -----------------TAYLAACAQDLCRCP-----TCP--CATFVEYSRQCAHAG--- 969
Query: 844 CGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCI 903
G+P + W +C P LCP R P + +EC
Sbjct: 970 -GQPRN------------------W----RC--PELCP------RTCPLNMQHQECG--- 995
Query: 904 CQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPG--- 960
C TC +P C DGC CPPG
Sbjct: 996 ----------------------------SPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSC 1027
Query: 961 TVLLD---ERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQAS 1017
TVL D C+P CPC H G+ Y P + C+ C C G W C G C
Sbjct: 1028 TVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGTCSVQ 1087
Query: 1018 GAPHYVTFDGLAFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEG- 1074
G H T+D + G C Y+L ++ A FTV A+ CG + C KA+ + L+G
Sbjct: 1088 GGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGG 1147
Query: 1075 -TVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD--GGTRVL 1131
T + + V +N + P L + F+++ T LGL LL +V
Sbjct: 1148 DTAIRVQADGGVFLNSIYTQLPLSAANITL-FTPSSFFIVVQTGLGLQLLVQLVPLMQVF 1206
Query: 1132 VQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEP-GDLPHP 1190
V+L P +G++ GLCG+F+ + ++D + GV+E T A++W+ C P
Sbjct: 1207 VRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDP 1266
Query: 1191 CTMNTHRAGWARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
C+++ +AR C L P F+ CH+ + P+ + C++D C C+ DC LC+A
Sbjct: 1267 CSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDC--LCAA 1324
Query: 1249 IATYADECARHGHHVRWRSQELCSL---QCEGGQVYEACGPTCPPTCHEQHPEPGWHCQV 1305
+++Y CA G + +C+ C Q Y C PTC E C V
Sbjct: 1325 LSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLS-EADVTCSV 1383
Query: 1306 -VACVEGCFCPEGTLLH-GGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCG 1363
V+GC CP GT L+ GAC+ CPC PG V+ + C+C G+ C
Sbjct: 1384 SFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSC- 1442
Query: 1364 GDGGHCEELVPACAEGEALCQENGHCVPHGWL-CDNQDDCGDGSDEEGCAAPGCGEGQMT 1422
G +L + G P +L C N G++ C +
Sbjct: 1443 --------------LGASLQKSTGCAAPMVYLDCSNSSAGTPGAE----CLRSCHTLDVG 1484
Query: 1423 CSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAAD 1482
C S HC+ G PP L+ DG C+ D
Sbjct: 1485 CFSTHCV-------------------------------SGCVCPPGLVSDGSGGCIAEED 1513
Query: 1483 EESCLGQVTCVPGEVSCVD-GTC 1504
+ T PGE VD TC
Sbjct: 1514 CPCVHNEATYKPGETIRVDCNTC 1536
Score = 240 bits (613), Expect = 2e-62
Identities = 176/572 (30%), Positives = 258/572 (45%), Gaps = 54/572 (9%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLA---GAADSTWAVHLTPGDRCPQPGHCQRVTMG 251
C++W FHY+TFDG + F G C Y+ + GAA + + L P RV M
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT-LSRVLMK 139
Query: 252 PEEVLIQA--GNVSVKGQ--LVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSI 307
+ V+IQ G+V V G L+P QS G+ +Q + + LG+V+ + S+
Sbjct: 140 VDGVVIQLTKGSVLVNGHPVLLPFSQS----GVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
Query: 308 SISVDHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVE 366
+ +D + +T GLCG +NG P + + L + FGN ++ C D V
Sbjct: 196 LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME--FGNLQKMDDPTEQCQDPVP 253
Query: 367 VAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEACLFAYCAG 425
EP + +C +LL G F C A V Y EAC C
Sbjct: 254 ---------------EPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCF- 297
Query: 426 AMAGSGQEGRQQAVCATFASYVQACARRH-IHIRWRKPGFCERLCPGGQLYSDCVSLCPP 484
VC T A Y + C + WR P FC + CP Y +C S C
Sbjct: 298 ----CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 485 SCEAVGQGEEESCREECVSGCECPRGLFWNG---TLCVPAAHCPCYYCRQRYVPGDTVRQ 541
+C Q +C + CV+GC CP G + T CVP + C C Y Y PG T
Sbjct: 354 TCS--NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYST 411
Query: 542 LCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQL 601
C C C GRW C + CP C+V G H+ TFDG+ Y+ G C Y L +
Sbjct: 412 DCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHG--DCSYVLTKPCDSSAF 469
Query: 602 LILLEHGAC---DAGSCLHAISVSLE--DTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVR 656
+L E C D+ +CL ++++SL+ T + ++ SG V +N LP I A +++
Sbjct: 470 TVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLP-ISAANVTIF 528
Query: 657 RASSAFLLLRWP-GAQVLWGLSDPV-AYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGD 714
R S+ F++ + G Q+ L + ++ L P+ Q GLCG F Q DDF T +G
Sbjct: 529 RPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGV 588
Query: 715 VETSIAAFASKFQVAGKGRCPSEDSALLSPCT 746
VE + AAF + F+ + CP+ ++ PC+
Sbjct: 589 VEATAAAFFNTFKT--QAACPNIRNSFEDPCS 618
Score = 166 bits (421), Expect = 4e-40
Identities = 104/369 (28%), Positives = 164/369 (44%), Gaps = 44/369 (11%)
Query: 1014 CQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFT-VSAQNLPCGASGLTCTKALAVRL 1072
C G+ HY TFDG F +PG C Y+ + + Q S + +++
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140
Query: 1073 EGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLV 1132
+G V+ + +G +V VNG V P ++ G+ ++++ + + LGL L+W+ +L+
Sbjct: 141 DGVVIQLTKG-SVLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLL 197
Query: 1133 QLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPL------------ 1180
+L ++ + GLCGDF+G + +EL +H+ +L+P+
Sbjct: 198 ELDTKYANKTCGLCGDFNG------------MPVVSELLSHNTKLTPMEFGNLQKMDDPT 245
Query: 1181 --CPEPGDLPHPCTMNTHRAGWARARCGALLQ-PLFTLCHAEVPPQQHYEWCLYDACGCD 1237
C +P +P P C LL LF+ C A V + E C D C C+
Sbjct: 246 EQCQDP--VPEP----PRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCE 299
Query: 1238 SGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQH 1296
C+C +A Y+ +C G + WR + C +C Y C C TC Q
Sbjct: 300 DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQ- 358
Query: 1297 PEPGWHCQVVACVEGCFCPEGTLLHG---GACLEPASCPCEWGRNSFPPGSVLQKDCGNC 1353
E C+ CV GCFCPEGT+L C+ + C C + ++ PG+ DC NC
Sbjct: 359 -EHSRACED-HCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNC 416
Query: 1354 TCQEGQWHC 1362
TC G+W C
Sbjct: 417 TCSGGRWSC 425
Score = 152 bits (383), Expect = 1e-35
Identities = 95/294 (32%), Positives = 138/294 (46%), Gaps = 15/294 (5%)
Query: 917 CPSQAFCPRELVY--APGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD---ERCVPP 971
CP + CP + Y C TC + + +C GC CP GTVL D CVP
Sbjct: 334 CPQK--CPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPV 391
Query: 972 DLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFT 1031
C C ++G Y P AT DC C C G +W C G C G H+ TFDG +T
Sbjct: 392 SKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYT 451
Query: 1032 YPGACEYLLVREA-SGLFTVSAQNLPCG-ASGLTCTKALAVRLEG--TVVHMLRGRAVTV 1087
G C Y+L + S FTV A+ CG TC K++ + L+G TVV + V +
Sbjct: 452 VHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFL 511
Query: 1088 NGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD--GGTRVLVQLSPQFRGRVAGL 1145
N + P + R + F++ T LGL L ++ +QL+P+ RG+ GL
Sbjct: 512 NQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGL 570
Query: 1146 CGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE-PGDLPHPCTMNTHRA 1198
CG+F+ ++D R+ GV+E TA ++++ CP PC+++ A
Sbjct: 571 CGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENA 624
Score = 149 bits (377), Expect = 5e-35
Identities = 185/764 (24%), Positives = 280/764 (36%), Gaps = 160/764 (20%)
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAF---CPRELVYAPGACLL 936
C C+ + ++PG + +R C + N +HC F CP A L
Sbjct: 5265 CFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCN---QHCDIDRFQGACPTSPPPVSSAPLS 5321
Query: 937 T-CDSPSANHSCPAGSTDG-----------CVCPPGTVLLDERCVPPDLCPCRHSGQWYL 984
+ +P +++ P + CV VLLD + V C +H +
Sbjct: 5322 SPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLP---I 5378
Query: 985 PNATIQEDCNV-----CVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYL 1039
+ + C+ C C G + G +G C G HY TFDG ++T+ G C Y+
Sbjct: 5379 KVSDPSQPCDFHYECECECVGGRGITPG---AGICSMWGGSHYSTFDGTSYTFRGNCTYV 5435
Query: 1040 LVREASGLF---TVSAQNLPCGASGLT------CTKALAVR-------LEGTVVHMLRGR 1083
L+RE F ++ N C AS C +AL++ L T+VH
Sbjct: 5436 LMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEG 5495
Query: 1084 AVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA 1143
+ + + V+ G +S+ + LG+++ ++G F
Sbjct: 5496 LILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTE 5555
Query: 1144 GLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL------------------SPLCP-EP 1184
G CG + +D R G + + A +W + SP P
Sbjct: 5556 GQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSS 5615
Query: 1185 GDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
P PC + C +L +F CH VPP + C+ D C G E
Sbjct: 5616 TPTPTPCP--------PQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEV 5663
Query: 1245 LCSAIATYADECARHGHHVRWRSQE--LCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWH 1302
C ++ YA+ C G WR LC L C +VY+ CGP P TC+ ++ P
Sbjct: 5664 PCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSP--- 5720
Query: 1303 CQVVACVEGCFCPEGTLL---HGGACLEPASCPCEWGRNSFP--PGSVLQKDCGNCTCQE 1357
Q+ EGCFCPE +L H G C++ +CPC G + FP PG +C +C C E
Sbjct: 5721 -QLEGMAEGCFCPEDQILFNAHMGICVQ--ACPCV-GPDGFPKFPGERWVSNCQSCVCDE 5776
Query: 1358 G---------------------------------------QWHCGGDGGHCEELVPACAE 1378
G + C + C + +P C
Sbjct: 5777 GSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPP 5836
Query: 1379 G-EALC-QENGHCVPHGWLCDNQDDCGDGS-DEEGCAAPGCGEGQM-TCSSGHCLPLALL 1434
G E++C QE G C P + C Q +G+ G PG M TC SG +
Sbjct: 5837 GQESICTQEEGDCCP-TFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQ 5895
Query: 1435 CDRQDDCGDGTDEPSYPCPQG-----LLACADGRCLPPALLC-DGHPDCLDAADEESCLG 1488
C ++D C + T CPQG + G C+ A L DG P L+ S +
Sbjct: 5896 C-QEDACNNTT------CPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVD 5948
Query: 1489 QVT------------CVPGEVSCVD-GTCLGAIQLCDGVWDCPD 1519
T P SC D +C G+++ + C +
Sbjct: 5949 NCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEE 5992
Score = 144 bits (364), Expect = 2e-33
Identities = 108/362 (29%), Positives = 150/362 (41%), Gaps = 18/362 (4%)
Query: 564 CAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSL 623
C+ G HY TFDG + F G +S I L A L + + +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140
Query: 624 EDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYI 683
+ IQL G+VLVNG V LP+ G+ ++++SS + G ++W D + +
Sbjct: 141 DGVVIQLT-KGSVLVNGHPVLLPF-SQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLL-L 197
Query: 684 TLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLS 743
LD ++A++ GLCG F L T + +F K P+E
Sbjct: 198 ELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPM-----EFGNLQKMDDPTEQCQ--D 250
Query: 744 PCTTHSQRHAFAEAACA-ILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGS--DCLCPV 800
P + + C +LH +F C LVD + C +C C+ C+C
Sbjct: 251 PVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHT 310
Query: 801 LSAYARRCAQEGASPP-WRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGEL-GSCVA 858
L+ Y+R+C G P WR CP CP +Y EC C C E CVA
Sbjct: 311 LAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVA 370
Query: 859 GCNCPLGLLWDPEGQ--CVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARH 916
GC CP G + D GQ CVP S C C YAPG+ +C C C G W+C
Sbjct: 371 GCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTC-SGGRWSCQEVP 429
Query: 917 CP 918
CP
Sbjct: 430 CP 431
Score = 138 bits (348), Expect = 1e-31
Identities = 148/557 (26%), Positives = 222/557 (39%), Gaps = 104/557 (18%)
Query: 41 PCASLDHYSRLGWRLDLPWSGRSGLTRS-PAPGLCPIYKPPETRPAKWNRTVRTCCPGWG 99
PCA+ YSR + G R+ P LCP R N + C
Sbjct: 954 PCATFVEYSR-------QCAHAGGQPRNWRCPELCP-------RTCPLNMQHQEC----- 994
Query: 100 GAHCTEALAKASP----EGHCFAMW------QCQLQAGSANASAGSLEECCARPWGQSWW 149
G+ CT+ + E HC C + ++ L +C G+++
Sbjct: 995 GSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYS 1054
Query: 150 DGSS--QACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPS-ATCASWSGFHYRTF 206
G+S C SC+ G LW P TC+ G H T+
Sbjct: 1055 PGTSFNTTCSSCTCS-------------------GGLWQCQDLPCPGTCSVQGGAHISTY 1095
Query: 207 DGRHYHFLGRCTYLLA-GAADSTWAV-------HLTPGDRCPQPGHCQRVTM----GPEE 254
D + Y G C+Y+L+ ADS++ V LT + C + VT+ G
Sbjct: 1096 DEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENC-----LKAVTLSLDGGDTA 1150
Query: 255 VLIQA-GNV---SVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLG--VVVRLDRTGSIS 308
+ +QA G V S+ QL + L S ++V+ GLG ++V+L +
Sbjct: 1151 IRVQADGGVFLNSIYTQLPLSAANITLFTPS----SFFIVVQTGLGLQLLVQLVPLMQVF 1206
Query: 309 ISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVA 368
+ +D GQ GLCG +N DDF G + A F N+W+ +++ C +A
Sbjct: 1207 VRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWK---AQAACANARNSF 1263
Query: 369 QGCDPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGA 426
+ DP L VE + A+ C +L + F +CH+ ++P +H C+F C
Sbjct: 1264 E--DPCSL---SVENENY---ARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTC--- 1312
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERL---CPGGQLYSDCVSLCP 483
E + +CA +SYV ACA + + + + G C + CP Q Y+ V C
Sbjct: 1313 ----NCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQ 1368
Query: 484 PSCEAVGQGEEE-SCREECVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQ 541
P+C + + + S V GC CP G F N CVPA CPCY PG+ V
Sbjct: 1369 PTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHD 1428
Query: 542 LCNPCVCRDGRWHCAQA 558
C C G+ C A
Sbjct: 1429 EGAVCSCTGGKLSCLGA 1445
Score = 134 bits (336), Expect = 3e-30
Identities = 147/546 (26%), Positives = 210/546 (38%), Gaps = 72/546 (13%)
Query: 546 CVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK--GQLLI 603
C C GR A C++ G HY TFDG SY+F G C Y L+++ G L +
Sbjct: 5395 CECVGGRGITPGA---GICSMWGGSHYSTFDGTSYTFRGN--CTYVLMREIHARFGNLSL 5449
Query: 604 LLEHGACDAGS--------CLHAISVSLEDTHIQLRDSGAVLVNGQDVGL---------P 646
L++ C A + C A+S+ + I L +V+G++ GL
Sbjct: 5450 YLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLT---VTMVHGKEEGLILFDQIPVSS 5506
Query: 647 WIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQ-VQGLCGTFTQNQQ 705
G+ V + + + P V + V L H +G CGT T NQ+
Sbjct: 5507 GFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQR 5566
Query: 706 DDFLTPAGDVETSIAAFASKFQV--AGKGRC--PSEDSALLSPC----TTHSQRHAFAEA 757
DD L G S A + V + K C P+ SP +T + +
Sbjct: 5567 DDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQP 5626
Query: 758 ACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPW 817
C ++ S VF ECH LV PF+ C++ C + C L AYA C G W
Sbjct: 5627 LCDLMLSQVFAECHNLVPPGPFFNACISD--HCRGRLEVPCQSLEAYAELCRARGVCSDW 5684
Query: 818 RNQT--LCPVMCPGGQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLG-LLWDPE-GQ 873
R T LC + CP + Y+ C P C +L GC CP +L++ G
Sbjct: 5685 RGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGI 5744
Query: 874 CVPPSLCPCQLGARRYA--PGSATMKECNRCICQERGL-WNCTARHCPSQAFCPRELVYA 930
CV CPC +G + PG + C C+C E + C C +Q P
Sbjct: 5745 CV--QACPC-VGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPP--CNR 5799
Query: 931 PGACLLTCDSPSANHSCPAGSTDGC----------VCPPG--TVLLDER--CVPPDLCP- 975
PG +T P A + C + C VCPPG ++ E C P C
Sbjct: 5800 PG--FVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRP 5857
Query: 976 --CRHSGQWYLPNATIQE--DCNVCVC-RGRQWHCTGQRRSGRCQASGAPHYVTFDGLAF 1030
C ++G +Y AT C++C C G T Q + C + P + +A
Sbjct: 5858 QLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAG 5917
Query: 1031 TYPGAC 1036
G C
Sbjct: 5918 QCCGEC 5923
Score = 109 bits (273), Expect = 6e-23
Identities = 104/434 (23%), Positives = 159/434 (36%), Gaps = 66/434 (15%)
Query: 158 SCSSRHLPGSASSPALLQPL-------AGAVGQLWSQHQRPSA-TCASWSGFHYRTFDGR 209
+C ++HLP S P+ QP VG + P A C+ W G HY TFDG
Sbjct: 5370 TCVNKHLPIKVSDPS--QPCDFHYECECECVG---GRGITPGAGICSMWGGSHYSTFDGT 5424
Query: 210 HYHFLGRCTYLLAGAADSTW---------------AVHLTPGDRCPQPGHCQRVTM---- 250
Y F G CTY+L + + A RCP+ +M
Sbjct: 5425 SYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVL 5484
Query: 251 ------GPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRT 304
G EE LI + P + +G+ + LG + + V +
Sbjct: 5485 TVTMVHGKEEGLILFDQI-------PVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFN 5537
Query: 305 GSI-SISVDHELW-GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGS-ESGC 361
G + + + L+ T+G CG DD ++ G A +W +P S + GC
Sbjct: 5538 GQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGC 5597
Query: 362 LDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFA 421
P + + P Q +C +L F +CH V P + AC+
Sbjct: 5598 WAPTGTPPTASPAAPVSSTPTP--TPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISD 5655
Query: 422 YCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWR--KPGFCERLCPGGQLYSDCV 479
+C GR + C + +Y + C R + WR G C+ CP ++Y C
Sbjct: 5656 HC---------RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCG 5706
Query: 480 SLCPPSCEAVGQGEEESCREECVSGCECPRG-LFWNGTLCVPAAHCPCYYCRQ-RYVPGD 537
+ P +C + Q + E GC CP + +N + + CPC PG+
Sbjct: 5707 PIQPATCNSRNQSPQ---LEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGE 5763
Query: 538 TVRQLCNPCVCRDG 551
C CVC +G
Sbjct: 5764 RWVSNCQSCVCDEG 5777
Score = 100 bits (250), Expect = 3e-20
Identities = 118/458 (25%), Positives = 169/458 (36%), Gaps = 104/458 (22%)
Query: 188 HQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA----------------------GAA 225
H+ TC ++ H+ TFDG Y F G C Y+LA G
Sbjct: 1547 HRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTT 1606
Query: 226 DSTWA--------VHLTPGDRCPQP------------GHCQRV-TMGPEEVLIQAGNVSV 264
+T + V P P P G QR+ + E+++Q G
Sbjct: 1607 GTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKA 1666
Query: 265 KGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCG 324
+ P G ++++G +LV+ G+ V DR S+ I + + G+ GLCG
Sbjct: 1667 VAR-GPGGDP----PYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCG 1720
Query: 325 LYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPG 384
++ +DF + A FGNSW+L S C DA+ C
Sbjct: 1721 NFDDNAINDFATRSRSVVGDALEFGNSWKLSPS---CPDALAPKDPC---------TANP 1768
Query: 385 HLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATF 443
++ AQ C +L GP F C +QV +Y+EAC+ CA SG G + C
Sbjct: 1769 FRKSWAQKQC-SILHGPTFAACRSQVDSTKYYEACVNDACA---CDSG--GDCECFCTAV 1822
Query: 444 ASYVQACARRHIHIRWRKPGFCERLC----PGGQL---YSDCVSLCPPSCE------AVG 490
A+Y QAC + + WR P C C P G Y C + C +C V
Sbjct: 1823 AAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVD 1882
Query: 491 QGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRY------VPGDTVRQLCN 544
E C +C P F+N A C CY Y VP + C
Sbjct: 1883 LPGLEGCYPKCP-----PSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVP---TAENCQ 1934
Query: 545 PCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSF 582
C C CA +L C T++ R+YS+
Sbjct: 1935 SCNCTPSGIQCAHSLEACTC---------TYEDRTYSY 1963
Score = 85.9 bits (211), Expect = 1e-15
Identities = 60/214 (28%), Positives = 77/214 (35%), Gaps = 20/214 (9%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLLHN-GTCVPPTACPC 4874
CP Q + +C C L + P GC CP G L++ G CVP CPC
Sbjct: 1354 CPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 1413
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPG----ETWQ 4930
H L PG V+ C C GG SC Q G +
Sbjct: 1414 YAHGTV-------------LAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYL 1460
Query: 4931 QVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLG 4990
+ G CL T S+ SGCVC PG +G C+ E+ C C H
Sbjct: 1461 DCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNE 1520
Query: 4991 RPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
+ PG + C +C C + R C+ TC
Sbjct: 1521 ATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTC 1554
Score = 82.0 bits (201), Expect = 1e-14
Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 6/101 (5%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD---GGCVPI 4114
C CP M+ C + C CS+ + C+D C GC CP+G++ D GCVP+
Sbjct: 334 CPQKCPNNMQYHECRSPCADTCSNQEHSRACEDH--CVAGCFCPEGTVLDDIGQTGCVPV 391
Query: 4115 GHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
C C G ++APG+ + C NC+C G+ SC PCP
Sbjct: 392 SKCACV-YNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCP 431
Score = 79.3 bits (194), Expect = 9e-14
Identities = 40/108 (37%), Positives = 48/108 (44%), Gaps = 10/108 (9%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHN---AS 2938
C +CP NM Q H+ PC C Q C C GC CP G L +
Sbjct: 334 CPQKCPNNM------QYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTG 387
Query: 2939 CLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
C+P S+C C +G YA GA D C NCTC G+ +C CP C
Sbjct: 388 CVPVSKCACVYNGAAYAPGATYSTD-CTNCTCSGGRWSCQEVPCPGTC 434
Score = 78.2 bits (191), Expect = 2e-13
Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 20/143 (13%)
Query: 4030 SCSSPPSKNGGAPCAGERHQARLCN-----------PMPCEAGCPAGMEVVTCANRCPRR 4078
+C+ + PCA +R C P C CP M+ C + C
Sbjct: 942 ACAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDT 1001
Query: 4079 CSDLQEGIVCQDDQVCQKGCRCPKG---SLEQD---GGCVPIGHCDCTDAQGHSWAPGSQ 4132
CS+ Q +C+D C GC CP G ++ D GC+P+G C CT G +++PG+
Sbjct: 1002 CSNPQRAQLCEDH--CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTS 1058
Query: 4133 HQDACNNCSCQAGQLSCTAQPCP 4155
C++C+C G C PCP
Sbjct: 1059 FNTTCSSCTCSGGLWQCQDLPCP 1081
Score = 77.8 bits (190), Expect = 3e-13
Identities = 98/384 (25%), Positives = 145/384 (37%), Gaps = 74/384 (19%)
Query: 1689 PEEQGCGAWGPW------SPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNC-----PGPEH 1737
P+ + G W P SP P S T P C + V C PGP
Sbjct: 5590 PDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGP-- 5647
Query: 1738 QSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTR 1797
F AC S+ CRG + + C S + C A G+ S
Sbjct: 5648 -----FFNAC--------------ISDHCRGRL--EVPCQSLEAYAELCRAR--GVCSDW 5684
Query: 1798 QTKPCPQDGCPNATCSGELMFQPCAPC-PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVL 1856
+ G + TC +++PC P P TC+ + P + GC+CPE Q+L
Sbjct: 5685 RGAT---GGLCDLTCPPTKVYKPCGPIQPATCNSRNQS----PQLEGMAEGCFCPEDQIL 5737
Query: 1857 GSEGWCVWPRQCPCL-VDGARYWPGQRIKADCQLCICQDG------RPRRCRLN---PDC 1906
+ + + CPC+ DG +PG+R ++CQ C+C +G +P C P C
Sbjct: 5738 FNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC 5797
Query: 1907 AVDCGWSSWSPWAKCLGPCGSQSI----QWSFRSSNNPRPSGRGRQCRGIHRKARRCQTE 1962
+ P A+ PC +++ + S P G+ C + C T
Sbjct: 5798 NRPGFVTVTRPRAE--NPCCPETVCVCNTTTCPQSLPVCPPGQESIC--TQEEGDCCPTF 5853
Query: 1963 PC--EGCEHQGQVHRVGERWHGG-PCRVCQCL----HNLTAHC-SPYCPLGSCPQGWVLV 2014
C + C + G + VG + G PC +C CL + T C C +CPQG+
Sbjct: 5854 RCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYK 5913
Query: 2015 EGTGESCCHC----ALPGENQTVQ 2034
G+ C C L + Q VQ
Sbjct: 5914 RVAGQCCGECVQTACLTPDGQPVQ 5937
Score = 76.3 bits (186), Expect = 8e-13
Identities = 38/89 (42%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
Query: 2634 PCPPSCLDPKANRSCSGHCVEGCRCPPG---LLLHD---TRCLPLSECPCLVGEELKWPG 2687
PC +C +P+ + C HCV+GC CPPG +L D + CLPL +CPC G PG
Sbjct: 997 PCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPG 1056
Query: 2688 VSFLLGNCSQCVCEKGELLCQPGGCPLPC 2716
SF CS C C G CQ CP C
Sbjct: 1057 TSFNT-TCSSCTCSGGLWQCQDLPCPGTC 1084
Score = 75.1 bits (183), Expect = 2e-12
Identities = 95/383 (24%), Positives = 121/383 (31%), Gaps = 115/383 (30%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLL---HNGTCVPPTACPC 4874
CPP +V C P C E GC CP Q+L H G CV ACPC
Sbjct: 5696 CPPTKVYKPCGPIQPATCNSRNQSPQL--EGMAEGCFCPEDQILFNAHMGICVQ--ACPC 5751
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAP 4934
P G PG NC CVC G+ S V C+ P + Q P
Sbjct: 5752 VG---PDGFPKF---------PGERWVSNCQSCVCDEGSVS---VQCKPLPCDAQGQPPP 5796
Query: 4935 -------------GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGH---FRSQAGPC 4978
E C +T N T + VC PG + G C
Sbjct: 5797 CNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLP-------VCPPGQESICTQEEGDC 5849
Query: 4979 VPEDHCE---CWHLGRPHLPGSEWQEA--CESCLCLSGRPV-----CTQH-CSPLTCAQG 5027
P C C + G + G+ + A C C CLSG C + C+ TC QG
Sbjct: 5850 CPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQG 5909
Query: 5028 EEMVLEPGSCCPSCRREA---PE---------------------------------EQSP 5051
E G CC C + A P+ Q
Sbjct: 5910 FEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPA 5969
Query: 5052 SCQLLTELRNFTK--GTCYL---------------------DQVEVSYCSGYCPSSTHVM 5088
SC ++ R + G CY +V +++C G CP ++
Sbjct: 5970 SCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTILWHQGCETEVNITFCEGSCPGASKYS 6029
Query: 5089 PEEPYLQSQCDCCSYRLDPESPV 5111
E +Q QC CC R E V
Sbjct: 6030 AEAQAMQHQCTCCQERRVHEETV 6052
Score = 72.8 bits (177), Expect = 8e-12
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Query: 2634 PCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHD---TRCLPLSECPCLVGEELKWPGVSF 2690
PC +C + + +R+C HCV GC CP G +L D T C+P+S+C C+ PG ++
Sbjct: 350 PCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 2691 LLGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G CQ CP C
Sbjct: 410 ST-DCTNCTCSGGRWSCQEVPCPGTC 434
Score = 72.0 bits (175), Expect = 1e-11
Identities = 46/169 (27%), Positives = 65/169 (38%), Gaps = 24/169 (14%)
Query: 4356 GCYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLI 4415
G Y C ++ + + C C L + Y Q CT G +
Sbjct: 285 GSYLEACRQDLCFCEDTDLLSCVCHTLAE--YSRQ------------CTHAGGLPQDWRG 330
Query: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKG-LLEQAG--GC 4472
+ C ++H C SPCA C+ + C+D C GC+CP+G +L+ G GC
Sbjct: 331 PDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACED--HCVAGCFCPEGTVLDDIGQTGC 388
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521
+P +C C + AA APG C C C G C C G
Sbjct: 389 VPVSKCACVYNGAA-----YAPGATYSTDCTNCTCSGGRWSCQEVPCPG 432
Score = 71.6 bits (174), Expect = 2e-11
Identities = 43/138 (31%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNT-QPCTAQCPENMLFRSAEQCHQE-GGPCPRLCLTQGP 2914
C++ C Q R+ + C CP NM HQE G PC C
Sbjct: 955 CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-------HQECGSPCTDTCSNPQR 1007
Query: 2915 GIECTGFCAPGCTCPPGLF------LHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNC 2968
C C GC CPPG + ++ CLP QCPC G+ Y+ G +C++C
Sbjct: 1008 AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFN-TTCSSC 1066
Query: 2969 TCVSGKMACTSERCPVAC 2986
TC G C CP C
Sbjct: 1067 TCSGGLWQCQDLPCPGTC 1084
Score = 70.5 bits (171), Expect = 4e-11
Identities = 109/405 (26%), Positives = 143/405 (35%), Gaps = 109/405 (26%)
Query: 3216 AVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHC--SRSCGGGLR 3273
A P + P P P P PLC + L Q P GP+ + S C G L
Sbjct: 5610 AAPVSSTPTPTPCPPQPLC-------DLMLSQVFAECHNLVPPGPFFNACISDHCRGRL- 5661
Query: 3274 SRTRACDQPPPQGLGDYCEGPRAQGEVCQ----------ALPCPVTNCTAIEGAEYSPCG 3323
+ P Q L Y E RA+G VC L CP T Y PCG
Sbjct: 5662 -------EVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKV-------YKPCG 5706
Query: 3324 PPCPRSCDDLVHC--VWRCQPGCYCPPGQVL-SSNGAICVQPGHCSCLDLLTGQRHHPGA 3380
P P +C+ + GC+CP Q+L +++ ICVQ C C+ G PG
Sbjct: 5707 PIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVG-PDGFPKFPGE 5763
Query: 3381 RLARPDGCNHCTCLEGRLN--CTDLPCPVPGGWCPWSE-------WTMCSQPCRGQTRSR 3431
R C C C EG ++ C LPC G P + PC +T
Sbjct: 5764 RWV--SNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCV 5821
Query: 3432 SRACACP-----TPQHGGAPCTGEAGEAGAQHQREACPSY----ATCPVDGAW---GPWG 3479
CP P + CT E G + CP++ C +G + G
Sbjct: 5822 CNTTTCPQSLPVCPPGQESICTQEEG--------DCCPTFRCRPQLCSYNGTFYGVGATF 5873
Query: 3480 PWS-PCDMCLGQSHRSR---------ACSRPPTPEG------GRPCPGNHTQS------- 3516
P + PC MC S ++ AC+ P+G C G Q+
Sbjct: 5874 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5933
Query: 3517 RPCQENST-------QCT----DCGGGQSLHPCGQPCPRSCQDLS 3550
+P Q N T CT + GG L P P SC D+S
Sbjct: 5934 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLL---TPQPASCPDVS 5975
Score = 68.2 bits (165), Expect = 2e-10
Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 31/153 (20%)
Query: 4377 CSCRVLVQ--QRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGS 4434
C C V+ ++ H G R R C R +C + CGS
Sbjct: 953 CPCATFVEYSRQCAHAGGQPRNWRCPELCPR----------------TCPLNMQHQECGS 996
Query: 4435 PCAGLCATHLSHQLCQDLPPCQPGCYCPKG----LLEQA--GGCIPPEECNCWHTSAAGA 4488
PC C+ QLC+D C GC+CP G +L+ GC+P +C C H
Sbjct: 997 PCTDTCSNPQRAQLCED--HCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH-----G 1049
Query: 4489 GMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521
G T +PG C C C G C C G
Sbjct: 1050 GRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPG 1082
Score = 67.8 bits (164), Expect = 3e-10
Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Query: 3318 EYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQVLSSNGAI-CVQPGHCSCLDLLTG 3373
+Y C PC +C + H C C GC+CP G VL G CV C+C+ G
Sbjct: 343 QYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACV--YNG 400
Query: 3374 QRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
+ PGA + C +CTC GR +C ++PCP
Sbjct: 401 AAYAPGATYSTD--CTNCTCSGGRWSCQEVPCP 431
Score = 67.0 bits (162), Expect = 5e-10
Identities = 56/200 (28%), Positives = 83/200 (41%), Gaps = 37/200 (18%)
Query: 4338 MAKADPTCNSTFLHLDTQGCYSGPCPEE---CVWSSWSSWTRCSC----RVLVQQRYRHQ 4390
+++AD TC+ +F+ +D C +G + CV + C C VL H
Sbjct: 1374 LSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQ-----ECPCYAHGTVLAPGEVVHD 1428
Query: 4391 GPA------SRGARAGAPCTRLDGHFRPCLISNCSEDSC-TPPFE-FHACGSPCAGLCAT 4442
A + + GA + G P + +CS S TP E +C + G +T
Sbjct: 1429 EGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFST 1488
Query: 4443 HLSHQLCQDLPPCQPGCYCPKGLLEQ-AGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLG 4501
H C GC CP GL+ +GGCI E+C C H A T PG+ +++
Sbjct: 1489 H-----------CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEA-----TYKPGETIRVD 1532
Query: 4502 CKECECRRGELHCTSQGCQG 4521
C C CR C+ + C G
Sbjct: 1533 CNTCTCRNRRWECSHRLCLG 1552
Score = 66.2 bits (160), Expect = 8e-10
Identities = 44/134 (32%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
Query: 1766 CRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APC 1824
C T CH+ R C G R CPQ CPN + + C +PC
Sbjct: 298 CEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQK-CPN-----NMQYHECRSPC 351
Query: 1825 PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGW--CVWPRQCPCLVDGARYWPGQR 1882
TC + C G C+CPEG VL G CV +C C+ +GA Y PG
Sbjct: 352 ADTCSNQEHSRACEDHCVAG---CFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGAT 408
Query: 1883 IKADCQLCICQDGR 1896
DC C C GR
Sbjct: 409 YSTDCTNCTCSGGR 422
Score = 66.2 bits (160), Expect = 8e-10
Identities = 55/201 (27%), Positives = 70/201 (34%), Gaps = 16/201 (7%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEG-IVCQDDQVCQKGCRCPKGSLEQDGG-CVPIGHCDC 4119
CP + C C L E + C V GC CP G+ D G CVP C C
Sbjct: 1354 CPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 1413
Query: 4120 TDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCA-------WSHWSAWSP-- 4170
A G APG D CSC G+LSC T CA S+ SA +P
Sbjct: 1414 Y-AHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGA 1472
Query: 4171 -CSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWL 4229
C SC SG P + CP C+ + G++ +
Sbjct: 1473 ECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCP--CVHNEATYKPGET-I 1529
Query: 4230 QGECQRCSCTPEGVICEDTEC 4250
+ +C C+C C C
Sbjct: 1530 RVDCNTCTCRNRRWECSHRLC 1550
Score = 65.9 bits (159), Expect = 1e-09
Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDC 3142
P CP + Q+ +C A +C+ R C GC CP G +L + CVP C
Sbjct: 335 PQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKC 394
Query: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
C + G Y PG+T C NC+C SG +C PC
Sbjct: 395 ACVYNGAAYAPGATYSTDCTNCTC-SGGRWSCQEVPC 430
Score = 65.9 bits (159), Expect = 1e-09
Identities = 72/278 (25%), Positives = 86/278 (30%), Gaps = 90/278 (32%)
Query: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD-GLCVPPAHCRCQYQPGAMGIPENQ 3600
C +C+ LS V S C CP G D G CVP C C Y G +
Sbjct: 1367 CQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC-YAHGTV------ 1419
Query: 3601 SRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS 3660
L PGEVV C+C G L S
Sbjct: 1420 -------------LAPGEVVHDEGAVCSCTGGKL-------------------------S 1441
Query: 3661 CGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVT 3720
C G +S CA P CS AG P R C T
Sbjct: 1442 CLGASLQKSTGCAAPMV------YLDCSNS---SAGTPGAECLRSCH------------T 1480
Query: 3721 QQVGCFSEGCEEGCHCPEGTFQHRL-ACV--QECPCVLTAWLLQELGATIGDPGQPLGPG 3777
VGCFS C GC CP G C+ ++CPCV AT
Sbjct: 1481 LDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNE-------AT----------- 1522
Query: 3778 DELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+T+R C C+C + + CS C +G
Sbjct: 1523 --YKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYG 1558
Score = 63.5 bits (153), Expect = 5e-09
Identities = 53/195 (27%), Positives = 66/195 (33%), Gaps = 29/195 (14%)
Query: 2811 SCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC---DGGIQTRGRSCSSLAPGDTTC 2867
+C G + + CS PV TC A D G + C A G
Sbjct: 1370 TCRGLSEADVTCSVSFVPVDGC--------TCPAGTFLNDAGACVPAQECPCYAHGTVLA 1421
Query: 2868 PGP--HSQTRDCNTQPCTAQC-------------PENMLFRSAEQCHQEGGPCPRLCLTQ 2912
PG H + C+ C P L S G C R C T
Sbjct: 1422 PGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTL 1481
Query: 2913 GPGIECTGFCAPGCTCPPGLFLH-NASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCV 2971
G T C GC CPPGL + C+ CPC + Y G R+D CN CTC
Sbjct: 1482 DVGCFST-HCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVD-CNTCTCR 1539
Query: 2972 SGKMACTSERCPVAC 2986
+ + C+ C C
Sbjct: 1540 NRRWECSHRLCLGTC 1554
Score = 60.5 bits (145), Expect = 4e-08
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 8/105 (7%)
Query: 3082 CAGPVPGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGML------LLNN 3134
C P CP + Q +C +C+ + C GC CP G + ++
Sbjct: 977 CPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHS 1036
Query: 3135 VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
C+P CPC H G Y PG++ C +C+C SG + C PC
Sbjct: 1037 GCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTC-SGGLWQCQDLPC 1080
Score = 59.7 bits (143), Expect = 7e-08
Identities = 32/96 (33%), Positives = 43/96 (44%), Gaps = 11/96 (11%)
Query: 3318 EYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQVLSSNGAI----CVQPGHCSCLDL 3370
++ CG PC +C + C C GC+CPPG+ + I C+ G C C
Sbjct: 990 QHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH- 1048
Query: 3371 LTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
G+ + PG C+ CTC G C DLPCP
Sbjct: 1049 -GGRTYSPGTSFNTT--CSSCTCSGGLWQCQDLPCP 1081
Score = 59.3 bits (142), Expect = 1e-07
Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 18/111 (16%)
Query: 4815 CPE-CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHN---GTCVPPT 4870
CP+ CP C + C C + + C ++ C GC CP G +L + CVP +
Sbjct: 334 CPQKCPNNMQYHECRSPCADTCSNQEHSRAC-EDHCVAGCFCPEGTVLDDIGQTGCVPVS 392
Query: 4871 ACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
C C + + PG + +CT C C GG +SC V C
Sbjct: 393 KCACVYNGAAYA-------------PGATYSTDCTNCTCSGGRWSCQEVPC 430
Score = 59.3 bits (142), Expect = 1e-07
Identities = 41/150 (27%), Positives = 63/150 (42%), Gaps = 12/150 (8%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQPCTA---QCPENMLFRSAEQCHQEGGPCPRLCLTQG 2913
C++L+ C Q D CT CP++ + Q P
Sbjct: 1322 CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQ-----PTCRGLSE 1376
Query: 2914 PGIECTGFCAP--GCTCPPGLFLHNA-SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTC 2970
+ C+ P GCTCP G FL++A +C+P +CPC HG + A G + D C+C
Sbjct: 1377 ADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVH-DEGAVCSC 1435
Query: 2971 VSGKMACTSERCPVACGWSPWTLWSLCSCS 3000
GK++C + G + ++ CS S
Sbjct: 1436 TGGKLSCLGASLQKSTGCAAPMVYLDCSNS 1465
Score = 57.8 bits (138), Expect = 3e-07
Identities = 42/141 (29%), Positives = 48/141 (34%), Gaps = 40/141 (28%)
Query: 3521 ENSTQCTDCGG-----------------GQSLHPCGQPCPRSCQDLSPGSVCQPGSV-GC 3562
E S QCT GG H C PC +C + C+ V GC
Sbjct: 313 EYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGC 372
Query: 3563 QPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTG 3622
G L + Q G CVP + C C Y A PG +
Sbjct: 373 FCPEGTVLDDIGQTG-CVPVSKCACVYNGAAYA--------------------PGATYST 411
Query: 3623 PCDNCTCVAGILQCQEVPDCP 3643
C NCTC G CQEVP CP
Sbjct: 412 DCTNCTCSGGRWSCQEVP-CP 431
Score = 57.8 bits (138), Expect = 3e-07
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 27/119 (22%)
Query: 4815 CPE-----CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQ-------LLH 4862
CPE CP C + C C + Q +C ++ C GC CP G+ + H
Sbjct: 977 CPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC-EDHCVDGCFCPPGRSCTVLDDITH 1035
Query: 4863 NGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
+G C+P CPCT + PGT C+ C C GG + C + C
Sbjct: 1036 SG-CLPLGQCPCTHGGRTYS-------------PGTSFNTTCSSCTCSGGLWQCQDLPC 1080
Score = 57.4 bits (137), Expect = 4e-07
Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 17/98 (17%)
Query: 4676 LDCAN--------QCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGR--CVPISSCRC 4725
LDC+N +C SC L V C C GC CPPG LV DG C+ C C
Sbjct: 1460 LDCSNSSAGTPGAECLRSCHTL--DVGCFSTHCVSGCVCPPG-LVSDGSGGCIAEEDCPC 1516
Query: 4726 GLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC 4763
A P + +++DC CTC N C H+ C
Sbjct: 1517 VHNEATYK----PGETIRVDCNTCTCRNRRWECSHRLC 1550
Score = 57.0 bits (136), Expect = 5e-07
Identities = 106/432 (24%), Positives = 147/432 (34%), Gaps = 91/432 (21%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF---QHRLACVQECPC 3753
CP ++Y+ C P + + + + Q+ EG EGC CPE H CVQ CPC
Sbjct: 5696 CPPTKVYKPCGPIQPATCNSRNQSPQL----EGMAEGCFCPEDQILFNAHMGICVQACPC 5751
Query: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLS--CSLDDCFEAD 3811
V G G P PG+ S +C +C C G +S C C +A
Sbjct: 5752 V-------------GPDGFPKFPGERWVS------NCQSCVCDEGSVSVQCKPLPC-DAQ 5791
Query: 3812 GGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEGS 3871
G P PC+R G T TR P C P C + CP +
Sbjct: 5792 G-----QP-PPCNRP--GFVTVTR--------PRAENPCC--PETVCVCNTTTCPQS--- 5830
Query: 3872 TVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCT---MGDPLQ-ERPCN 3927
PV P S C++ D P +R R +LC N T +G PC+
Sbjct: 5831 --LPVC-------PPGQESICTQEEGD-CCPTFRCRPQLCSYNGTFYGVGATFPGALPCH 5880
Query: 3928 LPSCTELPV-CPGPGCGAGNCSWTSWAPWEPCSRSCG--VGQQRRLRAYRPPGPGGHWCP 3984
+ +C P C C+ T+ R G G+ + P G
Sbjct: 5881 MCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNE 5940
Query: 3985 NILTAYQERRFCNLRACPVPGGWSRWSPW-SWCD--RSCGGGQSLRSRSCSSPPSKNGGA 4041
+ ++ + C + C GG +P + C SC G SLR C
Sbjct: 5941 TWVNSHVDN--CTVYLCEAEGGVHLLTPQPASCPDVSSCRG--SLRKTGCC--------Y 5988
Query: 4042 PCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR-- 4099
C + Q R+ + GC + + C CP E Q C + R
Sbjct: 5989 SCEEDSCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVH 6048
Query: 4100 -------CPKGS 4104
CP GS
Sbjct: 6049 EETVPLHCPNGS 6060
Score = 55.8 bits (133), Expect = 1e-06
Identities = 50/179 (27%), Positives = 63/179 (35%), Gaps = 21/179 (11%)
Query: 1732 CPGPEHQSQACFTAACPVDG----------EWSTWSPWSVCSEPCRGTMTRQRQCHSPQN 1781
C G C + PVDG + P C PC T +
Sbjct: 1371 CRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQEC--PCYAHGTVLAPGEVVHD 1428
Query: 1782 GGRTCAALPGGLHSTRQTKPCPQDGCPNAT----CSGELMFQPCAPCPLTCDDISGQVTC 1837
G C+ GG S GC CS P A C +C + V C
Sbjct: 1429 EGAVCSCT-GGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD--VGC 1485
Query: 1838 PPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGR 1896
C S GC CP G V G C+ CPC+ + A Y PG+ I+ DC C C++ R
Sbjct: 1486 FSTH-CVS-GCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRR 1542
Score = 55.5 bits (132), Expect = 1e-06
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 17/122 (13%)
Query: 4648 GGCREPWAQESCNGGP--CPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
GG + W GP CP+ + + + +C + C +C++ C + C GC
Sbjct: 322 GGLPQDWR------GPDFCPQ-KCPNNMQYHECRSPCADTCSNQEHSRAC-EDHCVAGCF 373
Query: 4706 CPPGQLVQD---GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQE 4762
CP G ++ D CVP+S C C A AP DC NCTC C
Sbjct: 374 CPEGTVLDDIGQTGCVPVSKCACVYNGA----AYAPGATYSTDCTNCTCSGGRWSCQEVP 429
Query: 4763 CP 4764
CP
Sbjct: 430 CP 431
Score = 55.5 bits (132), Expect = 1e-06
Identities = 55/212 (25%), Positives = 88/212 (41%), Gaps = 12/212 (5%)
Query: 152 SSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPS-ATCASWSGFHYRTFDGRH 210
S AC + + PG+ S G WS + P TC+ G H+ TFDG+
Sbjct: 392 SKCACVYNGAAYAPGATYSTDCTNCTCS--GGRWSCQEVPCPGTCSVLGGAHFSTFDGKQ 449
Query: 211 YHFLGRCTYLLAGAADSTWAVHLTPGDRC---PQPGHCQRVTMGPE----EVLIQAGNVS 263
Y G C+Y+L DS+ L RC + VT+ + V+I+A
Sbjct: 450 YTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEV 509
Query: 264 VKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLD--RTGSISISVDHELWGQTQG 321
Q+ + + + +++ LG+ + L T + + + +L GQT G
Sbjct: 510 FLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCG 569
Query: 322 LCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR 353
LCG +N DDF G + AA F N+++
Sbjct: 570 LCGNFNSIQADDFRTLSGVVEATAAAFFNTFK 601
Score = 55.5 bits (132), Expect = 1e-06
Identities = 50/217 (23%), Positives = 67/217 (30%), Gaps = 62/217 (28%)
Query: 4703 GCRCPPGQLVQD-GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQ 4761
GC CP G + D G CVP C C LAP + V + C+C L
Sbjct: 1390 GCTCPAGTFLNDAGACVPAQECPCYAHGT----VLAPGEVVHDEGAVCSCTGGKL----- 1440
Query: 4762 ECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPG 4821
C G ++++ C AP D C G
Sbjct: 1441 ----------------SCLGASLQKSTGC-----AAPMVYLD-----------CSNSSAG 1468
Query: 4822 QVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLH-NGTCVPPTACPCTQHSLP 4880
+ C SC L C C GC CP G + +G C+ CPC +
Sbjct: 1469 TPGAECLRSCHTL------DVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEAT 1522
Query: 4881 WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS 4917
+ PG + +C C C + CS
Sbjct: 1523 Y-------------KPGETIRVDCNTCTCRNRRWECS 1546
Score = 52.8 bits (125), Expect = 9e-06
Identities = 104/434 (23%), Positives = 150/434 (34%), Gaps = 122/434 (28%)
Query: 2634 PC----PPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRC-LPLSECPCLVGEEL-KWPG 2687
PC P +C + G EGC CP +L + + + CPC+ + K+PG
Sbjct: 5704 PCGPIQPATCNSRNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPG 5762
Query: 2688 VSFLLGNCSQCVCEKGELLCQPGGC-PLPCGWSAWSSWAPCDR-SCGSGVRARFRSPSNP 2745
++ NC CVC++G + Q C PLPC A PC+R + R R +P P
Sbjct: 5763 ERWV-SNCQSCVCDEGSVSVQ---CKPLPC--DAQGQPPPCNRPGFVTVTRPRAENPCCP 5816
Query: 2746 PAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCP 2805
VC T ++C QS +CP
Sbjct: 5817 ETV-----------------CVCNT-----------TTCPQSL-------------PVCP 5835
Query: 2806 SPGDSSC---PGDATQEEPCSPPVCPV-PSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLA 2861
+S C GD C P +C + +G+ A + + PC C+ L+
Sbjct: 5836 PGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPG-ALPC--------HMCTCLS 5886
Query: 2862 PGDTTCPGPHSQTRDCNTQPCTAQCPENMLF-RSAEQCHQEGGPCPR-LCLT-QGPGIE- 2917
GDT P Q CN CP+ + R A QC G C + CLT G ++
Sbjct: 5887 -GDTQDPTVQCQEDACN----NTTCPQGFEYKRVAGQC---CGECVQTACLTPDGQPVQL 5938
Query: 2918 -----------CTGFCAPGCTCPPGLFL---HNASCLPRSQCPCQLHGQLYASGAMARLD 2963
CT + C G+ L ASC S C G++ +
Sbjct: 5939 NETWVNSHVDNCTVYL---CEAEGGVHLLTPQPASCPDVSSC----------RGSLRKTG 5985
Query: 2964 SCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAE 3023
C +C + C V + LW C + F G+ P A+ AE
Sbjct: 5986 CC---------YSCEEDSCQVRINTT--ILWHQ---GCETEVNITFCEGSCPGASKYSAE 6031
Query: 3024 CQGPTMEAEFCSLR 3037
Q + C R
Sbjct: 6032 AQAMQHQCTCCQER 6045
Score = 52.4 bits (124), Expect = 1e-05
Identities = 99/398 (24%), Positives = 129/398 (32%), Gaps = 129/398 (32%)
Query: 3479 GPWSPCDMCLGQSHRSRACSRPPT--PEGGRPCPG----NHTQSRPCQENST--QCTD-- 3528
G + P D L +H P P+G PG ++ QS C E S QC
Sbjct: 5728 GCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLP 5787
Query: 3529 CGGGQSLHPCGQPC------PRSCQDLSPGSVCQPGSVGC-QPTCGCPLGQLS----QDG 3577
C PC +P PR+ P +VC + C Q CP GQ S ++G
Sbjct: 5788 CDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEG 5847
Query: 3578 LCVPPAHCR---CQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAG-- 3632
C P CR C Y G+ G+ F PG + PC CTC++G
Sbjct: 5848 DCCPTFRCRPQLCSYNGTFYGV--------GATF-------PGAL---PCHMCTCLSGDT 5889
Query: 3633 ---ILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQS----- 3684
+QCQE D + ++ + C G C + C P Q
Sbjct: 5890 QDPTVQCQE--DACNNTTCPQGFEYKRVAGQCCG-------ECVQTACLTPDGQPVQLNE 5940
Query: 3685 -------RTCSTQVC-----------REAGCPAGRLYRECQPGEGCPFSCAHVTQQV--- 3723
C+ +C + A CP R GC +SC + QV
Sbjct: 5941 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEEDSCQVRIN 6000
Query: 3724 -------GCFSE----GCEEGC------HCPEGTFQHRLACVQE-----------CP--- 3752
GC +E CE C QH+ C QE CP
Sbjct: 6001 TTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGS 6060
Query: 3753 -------------CVLTAWLLQELG---ATIGDPGQPL 3774
C L AW LQ G + DP QPL
Sbjct: 6061 AILHTYTHAVQVLCGLLAWGLQAGGHIRGAVQDPQQPL 6098
Score = 51.6 bits (122), Expect = 2e-05
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 5/88 (5%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGP--CVPEDHCECWHLGRPHLPGS 4997
C TC ++ C +GC C G G CVP C C + G + PG+
Sbjct: 351 CADTCSNQEHSRA---CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGA 407
Query: 4998 EWQEACESCLCLSGRPVCTQHCSPLTCA 5025
+ C +C C GR C + P TC+
Sbjct: 408 TYSTDCTNCTCSGGRWSCQEVPCPGTCS 435
Score = 51.6 bits (122), Expect = 2e-05
Identities = 51/205 (24%), Positives = 72/205 (35%), Gaps = 56/205 (27%)
Query: 2531 PLPGGSCPRDRFRSQS----------CFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQR 2580
P+ G +CP F + + C+ +A + + CS C GG S
Sbjct: 1387 PVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCS--CTGGKLS--- 1441
Query: 2581 SCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCL 2640
C GAS +++ T C VY+ C CL
Sbjct: 1442 -------------CLGASLQKS----------TGCAAPMVYLD---CSNSSAGTPGAECL 1475
Query: 2641 DPKANRSC--------SGHCVEGCRCPPGLLLHDT-RCLPLSECPCLVGEELKWPGVSFL 2691
RSC S HCV GC CPPGL+ + C+ +CPC+ E PG +
Sbjct: 1476 -----RSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIR 1530
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+ +C+ C C C C C
Sbjct: 1531 V-DCNTCTCRNRRWECSHRLCLGTC 1554
Score = 51.6 bits (122), Expect = 2e-05
Identities = 71/280 (25%), Positives = 98/280 (35%), Gaps = 50/280 (17%)
Query: 3090 CPRDKQWLDCAQ-GPASC-AELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDCPC 3144
CP K + C PA+C + +P+ GC CP +L N +CV Q CPC
Sbjct: 5696 CPPTKVYKPCGPIQPATCNSRNQSPQLEGMA--EGCFCPEDQILFNAHMGICV--QACPC 5751
Query: 3145 AH-EGHLYPPGSTVVRPCENCSCVSGLIA-NCSSWPC-AEGEPTWSPWTPWSQCSASCGP 3201
+G PG V C++C C G ++ C PC A+G+P P ++
Sbjct: 5752 VGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQP-----PPCNRPGFVTVT 5806
Query: 3202 ARCHRHRFCARSPSAVPSTVAPLPLPATP---TPLCSGPEAEEEP---CLLQGCDRAGGW 3255
+ C + +T P LP P +C+ E + P C Q C G +
Sbjct: 5807 RPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTF 5866
Query: 3256 GPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIE 3315
G + G L C L + P Q CQ C T C +
Sbjct: 5867 YGVG------ATFPGALPCHMCTC-------LSGDTQDPTVQ---CQEDACNNTTCP--Q 5908
Query: 3316 GAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSN 3355
G EY C C Q C P GQ + N
Sbjct: 5909 GFEYKRVAGQCCGEC---------VQTACLTPDGQPVQLN 5939
Score = 51.2 bits (121), Expect = 3e-05
Identities = 55/218 (25%), Positives = 76/218 (34%), Gaps = 45/218 (20%)
Query: 3435 CACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRS 3494
C P P G CT E G H+ P++A C + D+C R
Sbjct: 900 CPDPLPLPAGN-CTDEEGIC---HRTLLGPAFAECHALVDSTAYLAACAQDLC-----RC 950
Query: 3495 RACSRPPTPEGGRPCP--GNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPG 3552
C E R C G ++ C E + C CG PC +C +
Sbjct: 951 PTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT--CPLNMQHQECGSPCTDTCSNPQRA 1008
Query: 3553 SVCQPGSVGCQPTCGCPLGQ-------LSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAG 3605
+C+ C C CP G+ ++ G C+P C C + G
Sbjct: 1009 QLCEDH---CVDGCFCPPGRSCTVLDDITHSG-CLPLGQCPCTH---------------G 1049
Query: 3606 SRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
R S PG C +CTC G+ QCQ++P CP
Sbjct: 1050 GRTYS-----PGTSFNTTCSSCTCSGGLWQCQDLP-CP 1081
Score = 50.8 bits (120), Expect = 3e-05
Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 8/91 (8%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGP-----CVPEDHCECWHLGRPHL 4994
C TC N + Q C GC C PG + C+P C C H GR +
Sbjct: 998 CTDTC--SNPQRAQL-CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYS 1054
Query: 4995 PGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
PG+ + C SC C G C P TC+
Sbjct: 1055 PGTSFNTTCSSCTCSGGLWQCQDLPCPGTCS 1085
Score = 50.8 bits (120), Expect = 3e-05
Identities = 51/169 (30%), Positives = 62/169 (36%), Gaps = 28/169 (16%)
Query: 3239 AEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQG 3298
A+E PC G A G + CS C GG S C G Q
Sbjct: 1408 AQECPCYAHGTVLAPGEVVHDEGAVCS--CTGGKLS----------------CLGASLQK 1449
Query: 3299 EVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDL-VHCV-WRCQPGCYCPPGQVLSSNG 3356
A P +C+ + G C RSC L V C C GC CPPG V +G
Sbjct: 1450 STGCAAPMVYLDCS---NSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSG 1506
Query: 3357 AICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
C+ C C+ + PG + R D CN CTC R C+ C
Sbjct: 1507 G-CIAEEDCPCVH--NEATYKPGETI-RVD-CNTCTCRNRRWECSHRLC 1550
Score = 50.4 bits (119), Expect = 4e-05
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 9/86 (10%)
Query: 3090 CPRDKQWLDCAQGPASCAELSAPRGTNQT--------CHPGCHCPSGMLLLNNV-CVPTQ 3140
C +LDC+ A R + C GC CP G++ + C+ +
Sbjct: 1453 CAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEE 1512
Query: 3141 DCPCAHEGHLYPPGSTVVRPCENCSC 3166
DCPC H Y PG T+ C C+C
Sbjct: 1513 DCPCVHNEATYKPGETIRVDCNTCTC 1538
Score = 49.7 bits (117), Expect = 8e-05
Identities = 56/220 (25%), Positives = 73/220 (33%), Gaps = 42/220 (19%)
Query: 4556 LRDPTGLSPTLAPLLAS-----EQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG 4610
L PT P PL A E HR L PA Q LC
Sbjct: 893 LDGPTEQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLC---- 948
Query: 4611 ACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQ 4670
CP +C + + +S Q +GG WR E LC C + C G PC +
Sbjct: 949 RCP-TCPCATFVEYSR-QCAHAGGQPRNWRCPE-LCPRTCPLNMQHQEC-GSPCTDT--- 1001
Query: 4671 DTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQL------VQDGRCVPISSCR 4724
C+N R Q + C GC CPPG+ + C+P+ C
Sbjct: 1002 -------CSNP---------QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCP 1045
Query: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
C + +P + C +CTC C CP
Sbjct: 1046 C----THGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCP 1081
Score = 49.7 bits (117), Expect = 8e-05
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 15/118 (12%)
Query: 1784 RTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVTCPPDWP 1842
R CA G + R + CP+ TC + Q C +PC TC + C
Sbjct: 963 RQCAHAGGQPRNWRCPELCPR------TCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCV 1016
Query: 1843 CGSPGCWCPEGQ---VLG--SEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDG 1895
GC+CP G+ VL + C+ QCPC G Y PG C C C G
Sbjct: 1017 ---DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGG 1071
Score = 49.3 bits (116), Expect = 1e-04
Identities = 33/116 (28%), Positives = 42/116 (36%), Gaps = 28/116 (24%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF-----QHRLACVQEC 3751
CP Y EC+ C +C++ C + C GC CPEGT Q V +C
Sbjct: 338 CPNNMQYHECR--SPCADTCSNQEHSRAC-EDHCVAGCFCPEGTVLDDIGQTGCVPVSKC 394
Query: 3752 PCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
CV G G T T C NC+C+ G+ SC C
Sbjct: 395 ACVYN--------------------GAAYAPGATYSTDCTNCTCSGGRWSCQEVPC 430
Score = 48.1 bits (113), Expect = 2e-04
Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 3319 YSPCGPPCPRSC-DDLVHCVWRCQ--PGCY--CPPGQVLSSNGAI-CVQPGHCSCLDLLT 3372
Y PCG PC ++C + HC+ GCY CPP Q + + CV C C D
Sbjct: 1861 YQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYD-KD 1917
Query: 3373 GQRHHPGARLARPDGCNHCTCLEGRLNC 3400
G + GAR+ + C C C + C
Sbjct: 1918 GNYYDVGARVPTAENCQSCNCTPSGIQC 1945
Score = 47.4 bits (111), Expect = 4e-04
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Query: 3122 GCHCPSGMLLLN-NVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIA-------- 3172
GC CP+G L + CVP Q+CPC G + PG V CSC G ++
Sbjct: 1390 GCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQK 1449
Query: 3173 --NCSSWPCAEGEPTWSPWTPWSQCSASC 3199
C++ S TP ++C SC
Sbjct: 1450 STGCAAPMVYLDCSNSSAGTPGAECLRSC 1478
Score = 44.7 bits (104), Expect = 0.002
Identities = 119/558 (21%), Positives = 161/558 (28%), Gaps = 148/558 (26%)
Query: 4361 PCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPAS---RGARAGAPCTRLDGHFRPCLISN 4417
PCP + + S C LV S RG R PC L+ + C
Sbjct: 5621 PCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRG-RLEVPCQSLEAYAELCRARG 5679
Query: 4418 CSED-----------SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPK--- 4463
D +C P + CG C S L GC+CP+
Sbjct: 5680 VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCN---SRNQSPQLEGMAEGCFCPEDQI 5736
Query: 4464 ------GLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQ 4517
G+ QA C+ P+ G PG+R C+ C C G + S
Sbjct: 5737 LFNAHMGICVQACPCVGPD------------GFPKFPGERWVSNCQSCVCDEGSV---SV 5781
Query: 4518 GCQGLLPLSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRH 4577
C+ L PC P +R G P +
Sbjct: 5782 QCKPL-------------PCDAQGQPPPCNR-----------PGFVTVTRPRAENPCCPE 5817
Query: 4578 RLCLDPATGRPWT------GAPHLCTAPLSQQRLCPDPGACPDSCQWSLW----GPWSPC 4627
+C+ T P + G +CT + CP P C ++ G P
Sbjct: 5818 TVCVCNTTTCPQSLPVCPPGQESICTQ--EEGDCCPTFRCRPQLCSYNGTFYGVGATFPG 5875
Query: 4628 QVPCSGGFRLRWREAEALCGGGCREPWAQ---ESCNGGPCPECEAQDTVFTLDCANQCPH 4684
+PC G ++P Q ++CN CP+ V A QC
Sbjct: 5876 ALPC---------HMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRV-----AGQCCG 5921
Query: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRC---VPISSCRCGLPSANASWELAPAQA 4741
C + C P GQ VQ + +C L A L Q
Sbjct: 5922 ECV-------------QTACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQP 5968
Query: 4742 VQLDCQNCTCVNESL-------VCPHQECPV-LGPWSAWSSCSAPCGGGTMERHRTCEGG 4793
C + + SL C C V + W G T CEG
Sbjct: 5969 A--SCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTILWHQ-----GCETEVNITFCEGS 6021
Query: 4794 -PGVAPCQAQDTEQRQECNLQPCPE-----------CPPGQVL-----SACATSCPCLCW 4836
PG + A+ + +C C E CP G + A C L W
Sbjct: 6022 CPGASKYSAEAQAMQHQCTC--CQERRVHEETVPLHCPNGSAILHTYTHAVQVLCGLLAW 6079
Query: 4837 HLQPGAI---CVQEPCQP 4851
LQ G VQ+P QP
Sbjct: 6080 GLQAGGHIRGAVQDPQQP 6097
Score = 43.1 bits (100), Expect = 0.007
Identities = 35/143 (24%), Positives = 54/143 (37%), Gaps = 27/143 (18%)
Query: 3671 RCARPPCPGPARQSRTCS-----------TQVCREAGCPAGRLYRECQPGEGCPFSCAHV 3719
RC PC SR C+ ++C CP ++EC G C +C++
Sbjct: 949 RCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRT-CPLNMQHQEC--GSPCTDTCSNP 1005
Query: 3720 TQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDE 3779
+ C + C +GC CP G L + C+ L + T G G
Sbjct: 1006 QRAQLC-EDHCVDGCFCPPGRSCTVLDDITHSGCLP----LGQCPCTHG--------GRT 1052
Query: 3780 LDSGQTLRTSCGNCSCAHGKLSC 3802
G + T+C +C+C+ G C
Sbjct: 1053 YSPGTSFNTTCSSCTCSGGLWQC 1075
Score = 41.2 bits (95), Expect = 0.027
Identities = 29/110 (26%), Positives = 39/110 (35%), Gaps = 15/110 (13%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL---EQDGGCVPI 4114
C+ CP C P C+ + + +GC CP+ + G CV
Sbjct: 5692 CDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEG---MAEGCFCPEDQILFNAHMGICVQA 5748
Query: 4115 GHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLS-------CTAQPCPPP 4157
C C G PG + C +C C G +S C AQ PPP
Sbjct: 5749 --CPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPP 5796
Score = 40.8 bits (94), Expect = 0.035
Identities = 49/187 (26%), Positives = 65/187 (34%), Gaps = 26/187 (13%)
Query: 3980 GHWCPNILTAYQERRFCNLRACPV--PGGWSRWSPWSWCD--RSCGGGQSLRSRSCSSPP 4035
G +CP + ++ACP P G+ ++ W +SC + S C P
Sbjct: 5728 GCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLP 5787
Query: 4036 SKNGGAPCAGERH------QARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQ 4089
G P R + R NP E C TC P C QE I Q
Sbjct: 5788 CDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCN--TTTCPQSLPV-CPPGQESICTQ 5844
Query: 4090 DDQVCQKGCRCPKGSLEQDG----------GCVPIGHCDCTDAQGHSWAPGSQHQ-DACN 4138
++ C RC +G G +P C C G + P Q Q DACN
Sbjct: 5845 EEGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLS--GDTQDPTVQCQEDACN 5902
Query: 4139 NCSCQAG 4145
N +C G
Sbjct: 5903 NTTCPQG 5909
Score = 38.5 bits (88), Expect = 0.17
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 27/112 (24%)
Query: 3531 GGQSLH--PCGQPCPRSCQDLSPGSVC---QPGSVGCQPTCGCPLGQLSQDGL-CVPPAH 3584
GG H PCG PC ++C+ +P C PG GC P C ++D + CV A
Sbjct: 1855 GGCEWHYQPCGAPCLKTCR--NPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQ 1910
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQC 3636
C C + G G+R + E+ C +C C +QC
Sbjct: 1911 CGCYDKDG-------NYYDVGARVPTAEN----------CQSCNCTPSGIQC 1945
Score = 38.1 bits (87), Expect = 0.23
Identities = 54/197 (27%), Positives = 69/197 (35%), Gaps = 30/197 (15%)
Query: 1506 GAIQLCDGVWD-CPDGADEGPGHCPLPSLPTPPASTLPGPSPG---SLDTASSPLASAS- 1560
G +Q DG + CPD G+C TL GP+ +L +++ LA+ +
Sbjct: 888 GNLQKLDGPTEQCPDPLPLPAGNCT--DEEGICHRTLLGPAFAECHALVDSTAYLAACAQ 945
Query: 1561 -----PAPPCGPF---EFRCGSGECTPRGWRCDQ--EEDCADGSDERGCGGPCA-----P 1605
P PC F +C PR WRC + C + CG PC P
Sbjct: 946 DLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNP 1005
Query: 1606 HHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDAC---GGLPALGGPNRTGLPCPEY--T 1660
A HCV C R C D C G P G RT P + T
Sbjct: 1006 QRAQLCE-DHCVD-GCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTT 1062
Query: 1661 CPNGTCIGFQLVCDGQP 1677
C + TC G C P
Sbjct: 1063 CSSCTCSGGLWQCQDLP 1079
Score = 37.7 bits (86), Expect = 0.30
Identities = 39/168 (23%), Positives = 55/168 (32%), Gaps = 42/168 (25%)
Query: 4596 CTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWA 4655
CTA + + C D G C W C + C GGC W
Sbjct: 1819 CTAVAAYAQACHDAGLCVS------WRTPDTCPLFCDFYNP----------HGGCE--WH 1860
Query: 4656 QESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGC--RCPPGQ-LV 4712
+ C G PC + C N H DL P GC +CPP Q
Sbjct: 1861 YQPC-GAPCLKT----------CRNPSGHCLVDL---------PGLEGCYPKCPPSQPFF 1900
Query: 4713 QDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPH 4760
+ + ++ C C N +++ +CQ+C C + C H
Sbjct: 1901 NEDQMKCVAQCGCYDKDGNY-YDVGARVPTAENCQSCNCTPSGIQCAH 1947
Score = 37.7 bits (86), Expect = 0.30
Identities = 102/416 (24%), Positives = 125/416 (30%), Gaps = 101/416 (24%)
Query: 1501 DGTCLGAIQLCDGVWDCPDGADEG---PGHCPLPSLPTPPASTLPGPSPGSLDTA----- 1552
DGT + + W PD +G P P + P P S+ P P+P
Sbjct: 5573 DGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLML 5632
Query: 1553 SSPLASASPAPPCGPFEFRCGSGECTPR-GWRCDQEEDCAD-------GSDERGCGG--- 1601
S A P GPF C S C R C E A+ SD RG G
Sbjct: 5633 SQVFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLC 5692
Query: 1602 -----------PCAP-HHAPC------------ARGPHCVSPEQLCDG-----VRQCPDG 1632
PC P A C A G C + L + V+ CP
Sbjct: 5693 DLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQACP-- 5750
Query: 1633 SDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQ---LVCDGQ---PDCGRPGQVG 1686
GPD G P G R C C G+ + Q L CD Q P C RPG V
Sbjct: 5751 -CVGPD---GFPKFPG-ERWVSNCQSCVCDEGS-VSVQCKPLPCDAQGQPPPCNRPGFVT 5804
Query: 1687 PSPEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAA 1746
+ A P P C C +S P G Q + + C T
Sbjct: 5805 VTRPR----AENPCCPETVC--VCNTTTCPQSLPVCPPG----QESICTQEEGDCCPTFR 5854
Query: 1747 CPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDG 1806
C ++ T CH C L G T C +D
Sbjct: 5855 CR-----PQLCSYNGTFYGVGATFPGALPCH-------MCTCLSGDTQD--PTVQCQEDA 5900
Query: 1807 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQ-VLGSEGW 1861
C N TC P ++GQ C C P+GQ V +E W
Sbjct: 5901 CNNTTC----------PQGFEYKRVAGQCC----GECVQTACLTPDGQPVQLNETW 5942
Score = 35.8 bits (81), Expect = 1.1
Identities = 28/118 (23%), Positives = 35/118 (29%), Gaps = 16/118 (13%)
Query: 3099 CAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVV 3158
C G SC S + T GC P L +N T C H G
Sbjct: 1435 CTGGKLSCLGASLQKST------GCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFST 1488
Query: 3159 RPCENCSCVSGLIANCS-------SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRF 3209
C C GL+++ S PC E T+ P C C R+
Sbjct: 1489 HCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYK---PGETIRVDCNTCTCRNRRW 1543
Score = 34.7 bits (78), Expect = 2.5
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 3310 NCTAIEGAEY--SPCGPPCPRSCDDLVHCVWRCQP--GCYCPPGQVLSSNGAICVQPGHC 3365
NC + Y C P C + V C P GC CP G L+ GA CV C
Sbjct: 1353 NCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGA-CVPAQEC 1411
Query: 3366 SCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNC 3400
C G PG + +G C+C G+L+C
Sbjct: 1412 PC--YAHGTVLAPG-EVVHDEGA-VCSCTGGKLSC 1442
Score = 33.9 bits (76), Expect = 4.3
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 4/74 (5%)
Query: 2297 HWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHH--GESVQMVTTTPIPQMEAR 2354
H P + T+H P SP + T P P + P H G S T TP +
Sbjct: 4021 HTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTST 4080
Query: 2355 TLP--PGMAAVTVV 2366
LP P A +T V
Sbjct: 4081 LLPSSPTSAPITTV 4094
Score = 32.7 bits (73), Expect = 9.6
Identities = 38/166 (22%), Positives = 55/166 (33%), Gaps = 18/166 (10%)
Query: 4525 LSEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPA 4584
L W P P L P+ +A + L+ +LAP L SE +
Sbjct: 2399 LGTWRPSQP--PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSEL---------S 2447
Query: 4585 TGRPWTGAPHLCT--APLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREA 4642
T + T P T +PL+ C C+W+ W P SG
Sbjct: 2448 TSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWT---EWFDVDFPTSGVAGGDMETF 2504
Query: 4643 EALCGGGCREPWAQES--CNGGPCPECEAQDTVFTLDCANQCPHSC 4686
E + G + WA +S C PE L C+ + +C
Sbjct: 2505 ENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTC 2550
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 550 bits (1416), Expect = e-155
Identities = 373/1227 (30%), Positives = 559/1227 (45%), Gaps = 116/1227 (9%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTW---AVHLTPGD---RCPQPGHCQRV 248
C++W FHY+TFDG + F G C Y A ++ AVHL G P +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
Query: 249 TMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSIS 308
T+ + + + + G +V GL ++ + + G+ + +R ++
Sbjct: 97 TIKDDTIYLTRHLAVLNGAVVSTPH--YSPGLLIEKSDAYTKVYSRAGLTLMWNREDALM 154
Query: 309 ISVDHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEV 367
+ +D + T GLCG YNG +F+ G + L FGN ++ + C D E
Sbjct: 155 LELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE--FGNMQKINQPDVVCEDPEE- 211
Query: 368 AQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGP-FGQCHAQVSPAEYHEACLFAYCAGA 426
+V P +E + C +LL F C V Y AC C
Sbjct: 212 ------------EVAPASC-SEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCP 258
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIR---WRKPGFCERLCPGGQLYSDCVSLCP 483
G VC+T A + + C+ H R WR C + CPG +Y + S C
Sbjct: 259 -------GGDTCVCSTVAEFSRQCS--HAGGRPGNWRTATLCPKTCPGNLVYLESGSPCM 309
Query: 484 PSCEAVGQGEEESCREECVSGCECPRGLFWNG---TLCVPAAHCPCYYCRQRYVPGDTVR 540
+C + C E + GC CP G ++ + CVP + C C Y PG +
Sbjct: 310 DTCSHLEVSS--LCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEIT 367
Query: 541 QLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQ 600
C CVC GRW C CP CA+ G H TFDG++Y+F G C Y L +
Sbjct: 368 NDCEQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGD--CYYVLAKGDHNDS 425
Query: 601 LLILLEHGAC---DAGSCLHAISVSLEDTH---IQLRDSGAVLVNGQDVGLPWIGAEGLS 654
+L E C D +CL + V L D + + G+VL+N V LP + A S
Sbjct: 426 YALLGELAPCGSTDKQTCLKTV-VLLADKKKNVVVFKSDGSVLLNELQVNLPHVTAS-FS 483
Query: 655 VRRASSAFLLLRWPGAQVLWGLSDPVA--YITLDPRHAHQVQGLCGTFTQNQQDDFLTPA 712
V R SS +++ L PV ++TLD QVQGLCG F + DDF T +
Sbjct: 484 VFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTAS 543
Query: 713 GDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSV--FQEC 770
G VE + A FA+ ++ + C + L PC+ + + +AE C++L + F C
Sbjct: 544 GLVEATGAGFANTWKA--QSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRC 601
Query: 771 HRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPV---MC 827
H VD +Y RC C C DCLC LS+YAR C +G + +C C
Sbjct: 602 HSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSC 661
Query: 828 PGGQEYRECAPACGQHCGKPED----CGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQ 883
P Q + C Q C + C E + V GC CP D +G+CVP + C C
Sbjct: 662 PNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCY 721
Query: 884 LGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSA 943
G +++ RC+C++ L R P+ + L P A
Sbjct: 722 HRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRA 781
Query: 944 NHSCP---AG-----STDGCVCPPGTVLLDER---CVPPDLCPCRHSGQWYLPNATIQED 992
SC AG GCVCP G L+D+ CV CPC H+ Y A I+ D
Sbjct: 782 L-SCQTLAAGYYHTECVSGCVCPDG--LMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD 838
Query: 993 CNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVRE------ASG 1046
CN C C+ +W CT G C G+ HY+TFDG + + G C Y+ V++ + G
Sbjct: 839 CNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG 898
Query: 1047 LFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVN---GVSVTPPKVYTGPGL 1103
F++ +N+PCG +G+TC+KA+ + + T + + V + G V YT
Sbjct: 899 SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVA----YT---- 950
Query: 1104 SLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGV 1163
R G +L++ + G+ ++WD T V ++L+P ++G V GLCG+FD ++ND +R +
Sbjct: 951 -TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHM 1009
Query: 1164 LEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQ 1223
+ + +SW+ +P CP+ P PC++N HR WA +C L +F++CH++V P+
Sbjct: 1010 VVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPK 1069
Query: 1224 QHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQC-------E 1276
YE C++D+C CD+GGDCEC CSA+A+YA EC + G V WR+ +LC + C E
Sbjct: 1070 PFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHE 1129
Query: 1277 GGQVYEACGPTCPPTCHEQHPEPGWHCQV-VACVEGCF--CPEGTLLHG---GACLEPAS 1330
YE CG TC + G H + V+ +EGC+ CP+ ++ C+
Sbjct: 1130 CEWHYEPCGNRSFETCRTIN---GIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADK 1186
Query: 1331 CPCEWGRNSFPPGSVL--QKDCGNCTC 1355
C C +PPG+ + ++ C +C C
Sbjct: 1187 CGCYVEDTHYPPGASVPTEETCKSCVC 1213
Score = 169 bits (429), Expect = 5e-41
Identities = 108/358 (30%), Positives = 165/358 (46%), Gaps = 21/358 (5%)
Query: 1014 CQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCG---ASGLTCTKALAV 1070
C G HY TFDG F +PG C+Y + G + A +L G A +++ +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
Query: 1071 RLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRV 1130
++ +++ R AV +NG V+ P + PGL + ++ + + + GLTL+W+ +
Sbjct: 97 TIKDDTIYLTRHLAV-LNGAVVSTP--HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
Query: 1131 LVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSP--LCPEPGDLP 1188
+++L +FR GLCGD++G S GVL E P +C +P +
Sbjct: 154 MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEV 213
Query: 1189 HPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
P + + HRA R L F C VP + + C D C C GGD C+CS
Sbjct: 214 APASCSEHRAECERL----LTAEAFADCQDLVPLEPYLRACQQDRCRCP-GGDT-CVCST 267
Query: 1249 IATYADECARHGHHV-RWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA 1307
+A ++ +C+ G WR+ LC C G VY G C TC H E C+
Sbjct: 268 VAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC--SHLEVSSLCEEHR 325
Query: 1308 CVEGCFCPEGTL---LHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
++GCFCPEGT+ + C+ + C C + + PG + DC C C G+W C
Sbjct: 326 -MDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVC 382
Score = 160 bits (404), Expect = 4e-38
Identities = 179/705 (25%), Positives = 256/705 (36%), Gaps = 148/705 (20%)
Query: 882 CQLGARRYAPGSATMK----------ECNRCICQERGLWNCTARHCPSQAFCPRELVYAP 931
C L YAPG C+ E W+C + P+ P
Sbjct: 4336 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT---------P 4386
Query: 932 GACLLTCDSPSANHSCPAGSTDGCVCPP------------------------GTV-LLDE 966
T PS+ S P T CP TV ++
Sbjct: 4387 SKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKV 4446
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
C PP + C + L +++ C W C C G PHYVTFD
Sbjct: 4447 ECEPPPMPTCSNG----LQPVRVEDPDGCCW----HWECDCY-----CTGWGDPHYVTFD 4493
Query: 1027 GLAFTYPGACEYLLVREAS---GLFTVSAQNLPCGASG-LTCTKALAVRLEG-----TVV 1077
GL ++Y G C Y+LV E S F V N C + ++C + L VR E V
Sbjct: 4494 GLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTV 4553
Query: 1078 HMLRGRA-VTVNGVSVTPPKVYTGPGLSLRRAGL-FLLLSTHLGLTLLWDGGTRVLVQLS 1135
HM+ + V VN +V P Y GL + ++G+ +++ LG+ + ++G + +
Sbjct: 4554 HMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPY 4611
Query: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGD----- 1186
+F G CG S+D G + E AA W ++ P CP
Sbjct: 4612 HRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRP 4671
Query: 1187 ---LPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCE 1243
+P H+ C + LF CHA VPPQ +Y+ C++D+C G E
Sbjct: 4672 AVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM-PGSSLE 4730
Query: 1244 CLCSAIATYADECARHGHHVRWRSQE--LCSLQCEGGQVYEACGPTCPPTCHEQHPEPGW 1301
C+++ YA CA+ + WR+ C ++C + Y+ACGP PTC +
Sbjct: 4731 --CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQ-- 4786
Query: 1302 HCQVVACVEGCFCPEGTLLHGG---------ACLEPASCPCEWGRNSFPPGSVLQKDCGN 1352
VEGCFCPEGT+ + C+ P + P E+G + + DC N
Sbjct: 4787 --NNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEH-------FEFDCKN 4837
Query: 1353 CTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGW----------LCDNQDDC 1402
C C E GG G C+ C++ HCV G C N C
Sbjct: 4838 CVCLE-----GGSGIICQP--KRCSQKPVT-----HCVEDGTYLATEVNPADTCCNITVC 4885
Query: 1403 GDGSD---EEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLAC 1459
+ E+ P E + G C P C+ + C G E P C
Sbjct: 4886 KCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPF-YWCESKGVCVHGNAEYQPGSPVYSSKC 4944
Query: 1460 ADGRCLPPALLCDGHPDCLDAADEESCLGQVTC--VPGEVSCVDG 1502
D C+ C D D + L + C VP SC G
Sbjct: 4945 QD--CV-----------CTDKVDNNTLLNVIACTHVPCNTSCSPG 4976
Score = 142 bits (358), Expect = 9e-33
Identities = 114/384 (29%), Positives = 178/384 (46%), Gaps = 42/384 (10%)
Query: 194 TCASWSGFHYRTFDGRHYHFLGRCTYLLA-GAADSTWAV--HLTPGDRCPQPGHCQRVTM 250
TCA G H TFDG+ Y F G C Y+LA G + ++A+ L P + + V +
Sbjct: 390 TCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTVVL 449
Query: 251 ---GPEEVLIQAGNVSVKGQLVPEGQSWLLH---GLSLQWLGDWLVLSG---GLGVVVRL 301
+ V++ + SV L+ E Q L H S+ + ++ G+ + V+L
Sbjct: 450 LADKKKNVVVFKSDGSV---LLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQL 506
Query: 302 DRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGC 361
+ +++D GQ QGLCG +NG DDF G + A F N+W+ ++S C
Sbjct: 507 APVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWK---AQSSC 563
Query: 362 LDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEACL 419
D ++ DP L ++E + A+ C L E PFG+CH+ V PAEY++ C
Sbjct: 564 HDKLDWLD--DPCSL---NIESANY---AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCK 615
Query: 420 FAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCER---LCPGGQLYS 476
+ C + + +CA +SY +AC + + + + C + CP Q++
Sbjct: 616 YDTC-------NCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFL 668
Query: 477 DCVSLCPPSCEAVGQGEEESCRE--ECVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRY 533
++ C +C ++ + + C E V GC CP F + CVP A C CY+
Sbjct: 669 YNLTTCQQTCRSLSEADSH-CLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYL 727
Query: 534 VPGDTVRQLCNPCVCRDGRWHCAQ 557
GD V + CVCRDGR HC Q
Sbjct: 728 EAGDVVVRQEERCVCRDGRLHCRQ 751
Score = 137 bits (346), Expect = 2e-31
Identities = 136/489 (27%), Positives = 192/489 (39%), Gaps = 55/489 (11%)
Query: 553 WHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG--QLLILLEHGAC 610
WH C C GD HY+TFDG YS+ G C Y LV++ + +++ C
Sbjct: 4473 WHWE---CDCYCTGWGDPHYVTFDGLYYSYQGN--CTYVLVEEISPSVDNFGVYIDNYHC 4527
Query: 611 DAG---SCLHAISVSLEDTHIQLRD------SGAVLVNGQDVGLPWIGAEGLSVRRASSA 661
D SC + V E + ++ V VN Q V LP+ GL V ++
Sbjct: 4528 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY-KKYGLEVYQSGIN 4586
Query: 662 FLLLRWPGAQVLWGLSDPVAYITLD-PRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIA 720
+++ P VL + + L R + +G CGT T DD + P+G++ ++
Sbjct: 4587 YVV-DIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCE 4645
Query: 721 AFASKFQV--AGKGRCPSEDSALLSPCTT-------HSQRHAFAEAACAILHSSVFQECH 771
A A ++ V K CP S P T + C ++ S+F +CH
Sbjct: 4646 AAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCH 4705
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQT--LCPVMCPG 829
LV + +Y C+ C PGS C L AYA CAQ+ WRN T C V CP
Sbjct: 4706 ALVPPQHYYDACVFDSCFM-PGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPS 4764
Query: 830 GQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
+EY+ C PA C V GC CP G + G V C C +G
Sbjct: 4765 HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC-VGPDNV 4823
Query: 890 AP--GSATMKECNRCICQERGLW-NCTARHCPSQAFCPRELVYAPGACLLTCDSPS---A 943
G +C C+C E G C + C + P G L T +P+
Sbjct: 4824 PREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQK---PVTHCVEDGTYLATEVNPADTCC 4880
Query: 944 NHSCPAGSTDGC-----VCPPG----TVLLDERCVPPDLCP----CRHSGQWYLPNATI- 989
N + +T C VCP G + ++ RC P C C H Y P + +
Sbjct: 4881 NITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVY 4940
Query: 990 QEDCNVCVC 998
C CVC
Sbjct: 4941 SSKCQDCVC 4949
Score = 113 bits (283), Expect = 4e-24
Identities = 100/396 (25%), Positives = 155/396 (39%), Gaps = 56/396 (14%)
Query: 194 TCASWSGFHYRTFDGRHYHFLGRCTYL----LAGAADSTWAVH-LTPGDRCPQPG----H 244
TC+ + HY TFDG++Y F G C+Y+ G S + +T C G
Sbjct: 859 TCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSK 918
Query: 245 CQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRT 304
++ MG E+ ++ K ++V + + + +G +LV+ G++V D+
Sbjct: 919 AIKIFMGRTELKLED-----KHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKR 973
Query: 305 GSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDA 364
++ I + G GLCG ++ +DF + FGNSW+ C D
Sbjct: 974 TTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK---EAPTCPDV 1030
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
+ C + P H R+ A+ C L F CH++V P ++EAC+ C+
Sbjct: 1031 STNPEPC--------SLNP-HRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCS 1081
Query: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPP 484
G + C+ ASY Q C + + WR P C C Y + C
Sbjct: 1082 CDTGGD-----CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD----YYNPPHECEW 1132
Query: 485 SCEAVGQGEEESCR--------------EECVSGCECPRGLFWNG-TLCVPAAHCPCYYC 529
E G E+CR E C C R ++ CV A C CY
Sbjct: 1133 HYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVE 1192
Query: 530 RQRYVPGDTV--RQLCNPCVCRDGRWHCAQALCPAE 563
Y PG +V + C CVC + +Q +C E
Sbjct: 1193 DTHYPPGASVPTEETCKSCVCTNS----SQVVCRPE 1224
Score = 102 bits (253), Expect = 1e-20
Identities = 106/401 (26%), Positives = 151/401 (37%), Gaps = 68/401 (16%)
Query: 188 HQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL----AGAADSTWA----VHLTPGDR- 238
H C W HY TFDG +Y + G CTY+L + + D+ H P D+
Sbjct: 4474 HWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKV 4533
Query: 239 -CP---------QPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEG----QSWLLHGLSLQW 284
CP Q + V M P +V +Q +V G QS + + + +
Sbjct: 4534 SCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 4593
Query: 285 LGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAML 344
LG LV GL VRL H T+G CG DD + P G +
Sbjct: 4594 LG-VLVSYNGLSFSVRLPY---------HRFGNNTKGQCGTCTNTTSDDCILPSGEIVSN 4643
Query: 345 AATFGNSWRL-PGSESGCLDAVEVAQGCDPLGLIDADVEPG------HLRAEAQDVCHQL 397
+ W + S+ C + + A PG H +C +
Sbjct: 4644 CEAAADQWLVNDPSKPHCPHSSSTTKR-------PAVTVPGGGKTTPHKDCTPSPLCQLI 4696
Query: 398 LEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI 457
+ F QCHA V P Y++AC+F C M GS E CA+ +Y CA+++I +
Sbjct: 4697 KDSLFAQCHALVPPQHYYDACVFDSC--FMPGSSLE------CASLQAYAALCAQQNICL 4748
Query: 458 RWRK--PGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNG 515
WR G C CP + Y C P+C++ + + V GC CP G
Sbjct: 4749 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV---LVEGCFCPEGTMNYA 4805
Query: 516 ---TLCVPAAHC--PCYYCRQRYVPGDTVRQLCNPCVCRDG 551
+CV C P R+ G+ C CVC +G
Sbjct: 4806 PGFDVCVKTCGCVGPDNVPREF---GEHFEFDCKNCVCLEG 4843
Score = 79.3 bits (194), Expect = 9e-14
Identities = 65/228 (28%), Positives = 77/228 (33%), Gaps = 47/228 (20%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLL-HNGTCVPPTACPC 4874
CP QV T+C C L E P GCGCP L G CVP C C
Sbjct: 661 CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC 720
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV-----DCQVPPGETW 4929
L L G V+ R RCVC G C + C P
Sbjct: 721 YHRGL-------------YLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPK---- 763
Query: 4930 QQVAPGELGLCEQTCLEMNATKTQS----NCSSARA--------SGCVCQPGHFRSQAGP 4977
C + A T +C + A SGCVC G G
Sbjct: 764 ----------IHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGG 813
Query: 4978 CVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
CV E C C H + G++ + C +C C GR VCTQ TC+
Sbjct: 814 CVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCS 861
Score = 76.6 bits (187), Expect = 6e-13
Identities = 51/176 (28%), Positives = 72/176 (40%), Gaps = 27/176 (15%)
Query: 3983 CPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAP 4042
C +++ R C C PGG D + SR CS GG P
Sbjct: 237 CQDLVPLEPYLRACQQDRCRCPGG----------DTCVCSTVAEFSRQCSHA----GGRP 282
Query: 4043 CAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPK 4102
G A LC CP + + + C CS L+ +C++ ++ GC CP+
Sbjct: 283 --GNWRTATLCPKT-----CPGNLVYLESGSPCMDTCSHLEVSSLCEEHRM--DGCFCPE 333
Query: 4103 GSLEQD---GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
G++ D GCVP+ C C GH + PG + + C C C AG+ C PCP
Sbjct: 334 GTVYDDIGDSGCVPVSQCHCR-LHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCP 388
Score = 68.9 bits (167), Expect = 1e-10
Identities = 40/134 (29%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
CS++A C + + T C CP N+++ + G PC C
Sbjct: 265 CSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYL------ESGSPCMDTCSHLEVS 318
Query: 2916 IECTGFCAPGCTCPPGLF---LHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVS 2972
C GC CP G + ++ C+P SQC C+LHG LY G D C C C +
Sbjct: 319 SLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITND-CEQCVCNA 377
Query: 2973 GKMACTSERCPVAC 2986
G+ C CP C
Sbjct: 378 GRWVCKDLPCPGTC 391
Score = 66.6 bits (161), Expect = 6e-10
Identities = 42/125 (33%), Positives = 56/125 (44%), Gaps = 14/125 (11%)
Query: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMF-QPCAPCPLTCDDISGQ 1834
C + R C+ G + R CP+ TC G L++ + +PC TC +
Sbjct: 265 CSTVAEFSRQCSHAGGRPGNWRTATLCPK------TCPGNLVYLESGSPCMDTCSHLEVS 318
Query: 1835 VTCPPDWPCGSPGCWCPEGQV---LGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCI 1891
C GC+CPEG V +G G CV QC C + G Y PGQ I DC+ C+
Sbjct: 319 SLCEEH---RMDGCFCPEGTVYDDIGDSG-CVPVSQCHCRLHGHLYTPGQEITNDCEQCV 374
Query: 1892 CQDGR 1896
C GR
Sbjct: 375 CNAGR 379
Score = 65.5 bits (158), Expect = 1e-09
Identities = 57/178 (32%), Positives = 67/178 (37%), Gaps = 29/178 (16%)
Query: 4874 CTQHSLPWGLTLTLEEQA--QELPPGTVLTRNCT--RCVCHGG-AFSCSLV-----DCQV 4923
C++H LT E A Q+L P R C RC C GG CS V C
Sbjct: 218 CSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSH 277
Query: 4924 PPGE--TWQ------QVAPGEL------GLCEQTCLEMNATKTQSNCSSARASGCVCQPG 4969
G W+ + PG L C TC + + S C R GC C G
Sbjct: 278 AGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVS---SLCEEHRMDGCFCPEG 334
Query: 4970 HFRSQAGP--CVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
G CVP C C G + PG E CE C+C +GR VC P TCA
Sbjct: 335 TVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPGTCA 392
Score = 63.9 bits (154), Expect = 4e-09
Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Query: 2634 PCPPSCLDPKANRSCSGHCVEGCRCPPGLL---LHDTRCLPLSECPCLVGEELKWPGVSF 2690
PC +C + + C H ++GC CP G + + D+ C+P+S+C C + L PG
Sbjct: 307 PCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQE- 365
Query: 2691 LLGNCSQCVCEKGELLCQPGGCPLPC 2716
+ +C QCVC G +C+ CP C
Sbjct: 366 ITNDCEQCVCNAGRWVCKDLPCPGTC 391
Score = 63.9 bits (154), Expect = 4e-09
Identities = 40/159 (25%), Positives = 58/159 (36%), Gaps = 31/159 (19%)
Query: 1232 DACGC------DSGGDC----ECLC----------SAIATYADECARHGHHVRWRSQELC 1271
D CGC D G C +C C + + C + R L
Sbjct: 696 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 755
Query: 1272 SLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA-------CVEGCFCPEGTLLHG-G 1323
C +++ C T CQ +A CV GC CP+G + G G
Sbjct: 756 GQSCTAPKIHMDCSNL---TALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRG 812
Query: 1324 ACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C+ CPC + + G+ ++ DC CTC+ G+W C
Sbjct: 813 GCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVC 851
Score = 62.4 bits (150), Expect = 1e-08
Identities = 53/194 (27%), Positives = 73/194 (37%), Gaps = 26/194 (13%)
Query: 4338 MAKADPTCNSTFLHLDTQGCYSGPCPEE---CVWSSWSSWTRCSCRVLVQQRYRHQGPAS 4394
+++AD C F +D GC +E CV +CSC R +
Sbjct: 681 LSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCV-----PLAKCSC----YHRGLYLEAGD 731
Query: 4395 RGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPP 4454
R C DG C SCT P + H S L + CQ L
Sbjct: 732 VVVRQEERCVCRDGRLH-CRQIRLIGQSCTAP-KIHMDCSNLTALATSKPRALSCQTLAA 789
Query: 4455 ------CQPGCYCPKGLLEQA-GGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECEC 4507
C GC CP GL++ GGC+ +EC C H + + G ++++ C C C
Sbjct: 790 GYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDL-----YSSGAKIKVDCNTCTC 844
Query: 4508 RRGELHCTSQGCQG 4521
+RG CT C G
Sbjct: 845 KRGRWVCTQAVCHG 858
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 2922 CAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSE 2980
C GC CP GL C+ +CPC + LY+SGA ++D CN CTC G+ CT
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD-CNTCTCKRGRWVCTQA 854
Query: 2981 RCPVAC 2986
C C
Sbjct: 855 VCHGTC 860
Score = 58.2 bits (139), Expect = 2e-07
Identities = 100/457 (21%), Positives = 151/457 (33%), Gaps = 119/457 (26%)
Query: 4703 GCRCPPGQL-VQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQ 4761
GC CP G + G V + +C C P N E + + DC+NC C+
Sbjct: 4794 GCFCPEGTMNYAPGFDVCVKTCGCVGPD-NVPREFG--EHFEFDCKNCVCLEG------- 4843
Query: 4762 ECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPG 4821
G G + + + C P V C T E N P C
Sbjct: 4844 ------------------GSGIICQPKRCSQKP-VTHCVEDGTYLATEVN--PADTCCNI 4882
Query: 4822 QVLSACATSC---PCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHS 4878
V + C P +C P V+ PG CP G CV A
Sbjct: 4883 TVCKCNTSLCKEKPSVC----PLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA------- 4931
Query: 4879 LPWGLTLTLEEQAQELPPGT-VLTRNCTRCVCHG--------GAFSCSLVDCQVPPGETW 4929
E PG+ V + C CVC +C+ V C +
Sbjct: 4932 --------------EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGF 4977
Query: 4930 QQV-APGELGLCEQTCLEMNATKTQSNCSSARASG--CVCQPGHFRSQAGPCVPEDHCEC 4986
+ + APGE C + C Q++C R + +PG F+S P+++C
Sbjct: 4978 ELMEAPGE---CCKKC-------EQTHCIIKRPDNQHVILKPGDFKSD-----PKNNCTF 5022
Query: 4987 WHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGS-------CCP 5039
+ SC+ + + + + S +TC + + PGS CC
Sbjct: 5023 F-----------------SCVKIHNQLISS--VSNITCPNFDASICIPGSITFMPNGCCK 5063
Query: 5040 SCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCD 5099
+C E C + + C V +++CSG C + + L C
Sbjct: 5064 TCTPR--NETRVPCSTVPVTTEVSYAGC-TKTVLMNHCSGSCGTFVMYSAKAQALDHSCS 5120
Query: 5100 CCSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQC 5136
CC + ++ R + L C G + I SCQC
Sbjct: 5121 CCK---EEKTSQREVVLSCPNGGSLTHTYTHIESCQC 5154
Score = 56.6 bits (135), Expect = 6e-07
Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 5/97 (5%)
Query: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGML---LLNNVCVPTQDC 3142
P CP + +L+ +C+ L + GC CP G + + ++ CVP C
Sbjct: 292 PKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQC 351
Query: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
C GHLY PG + CE C C +G C PC
Sbjct: 352 HCRLHGHLYTPGQEITNDCEQCVCNAGRWV-CKDLPC 387
Score = 55.8 bits (133), Expect = 1e-06
Identities = 51/190 (26%), Positives = 69/190 (36%), Gaps = 55/190 (28%)
Query: 3457 QHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQS 3516
Q R CP TC +C + SR CS GGRP GN +
Sbjct: 251 QQDRCRCPGGDTC----------------VCSTVAEFSRQCSHA----GGRP--GNWRTA 288
Query: 3517 RPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD 3576
C + C G G PC +C L S+C+ + C CP G + D
Sbjct: 289 TLCPKT------CPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMD---GCFCPEGTVYDD 339
Query: 3577 ---GLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGI 3633
CVP + C C R G ++ PG+ +T C+ C C AG
Sbjct: 340 IGDSGCVPVSQCHC--------------RLHGHLYT------PGQEITNDCEQCVCNAGR 379
Query: 3634 LQCQEVPDCP 3643
C+++P CP
Sbjct: 380 WVCKDLP-CP 388
Score = 55.8 bits (133), Expect = 1e-06
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 4815 CPE-CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQL---LHNGTCVPPT 4870
CP+ CP V + C C HL+ ++C +E GC CP G + + + CVP +
Sbjct: 291 CPKTCPGNLVYLESGSPCMDTCSHLEVSSLC-EEHRMDGCFCPEGTVYDDIGDSGCVPVS 349
Query: 4871 ACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
C C H PG +T +C +CVC+ G + C + C
Sbjct: 350 QCHCRLH-------------GHLYTPGQEITNDCEQCVCNAGRWVCKDLPC 387
Score = 55.5 bits (132), Expect = 1e-06
Identities = 33/92 (35%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 3319 YSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQVLSSNG-AICVQPGHCSCLDLLTGQ 3374
Y G PC +C L C GC+CP G V G + CV C C L G
Sbjct: 301 YLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCR--LHGH 358
Query: 3375 RHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
+ PG + + C C C GR C DLPCP
Sbjct: 359 LYTPGQEIT--NDCEQCVCNAGRWVCKDLPCP 388
Score = 54.7 bits (130), Expect = 2e-06
Identities = 49/180 (27%), Positives = 63/180 (35%), Gaps = 20/180 (11%)
Query: 1730 QNCPGPEHQSQACFTAACPVDG----------EWSTWSPWSVCSEPCRGTMTRQRQCHSP 1779
Q C C PVDG E P + CS RG
Sbjct: 676 QTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVR 735
Query: 1780 QNGGRTCAALPGGLHSTRQTKPCPQDGCP---NATCSGELMFQPCAPCPLTCDDISGQVT 1836
Q C G LH RQ + Q + CS P L+C ++
Sbjct: 736 QE--ERCVCRDGRLHC-RQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYY 792
Query: 1837 CPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGR 1896
C S GC CP+G + G CV ++CPC+ + Y G +IK DC C C+ GR
Sbjct: 793 ---HTECVS-GCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGR 848
Score = 53.9 bits (128), Expect = 4e-06
Identities = 66/276 (23%), Positives = 94/276 (34%), Gaps = 76/276 (27%)
Query: 4654 WAQESCNG--GPCPECEAQDTVFTLDCANQCPHSCADLWDR-VQCLQGPCR-PGCRCPPG 4709
W + CN G CP + VF + C +C L + CL+G GC CP
Sbjct: 649 WREHVCNKDVGSCPNSQ----VFLYNLTT-CQQTCRSLSEADSHCLEGFAPVDGCGCPDH 703
Query: 4710 QLVQD-GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP 4768
+ + GRCVP++ C C + L V + C C + L C ++ ++G
Sbjct: 704 TFLDEKGRCVPLAKCSC----YHRGLYLEAGDVVVRQEERCVCRDGRLHC--RQIRLIG- 756
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
SC+AP + H C L+A A
Sbjct: 757 ----QSCTAP------KIHMDCSN-------------------------------LTALA 775
Query: 4829 TSCP--CLCWHLQPGAICVQEPCQPGCGCPGGQLLH-NGTCVPPTACPCTQHSLPWGLTL 4885
TS P C L G + C GC CP G + G CV CPC ++
Sbjct: 776 TSKPRALSCQTLAAGYYHTE--CVSGCVCPDGLMDDGRGGCVVEKECPCVHNN------- 826
Query: 4886 TLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
G + +C C C G + C+ C
Sbjct: 827 ------DLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 856
Score = 53.9 bits (128), Expect = 4e-06
Identities = 62/271 (22%), Positives = 82/271 (30%), Gaps = 93/271 (34%)
Query: 3542 CPRSCQDLSPG-SVCQPGSVGCQPTCGCPLGQ-LSQDGLCVPPAHCRCQYQPGAMGIPEN 3599
C ++C+ LS S C G CGCP L + G CVP A C C Y G
Sbjct: 674 CQQTCRSLSEADSHCLEGFAPVDG-CGCPDHTFLDEKGRCVPLAKCSC-YHRGLY----- 726
Query: 3600 QSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSV 3659
LE G+VV + C C G L C+++
Sbjct: 727 --------------LEAGDVVVRQEERCVCRDGRLHCRQI-------------------- 752
Query: 3660 SCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHV 3719
+L + C P +T R C
Sbjct: 753 ------RLIGQSCTAPKIHMDCSNLTALATSKPRALSCQ--------------------- 785
Query: 3720 TQQVGCFSEGCEEGCHCPEGTFQH-RLACV--QECPCVLTAWLLQELGATIGDPGQPLGP 3776
T G + C GC CP+G R CV +ECPCV
Sbjct: 786 TLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN-------------------- 825
Query: 3777 GDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
D SG ++ C C+C G+ C+ C
Sbjct: 826 NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 856
Score = 53.1 bits (126), Expect = 7e-06
Identities = 59/240 (24%), Positives = 89/240 (37%), Gaps = 38/240 (15%)
Query: 1812 CSGELMFQPCAPCPL-TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPC 1870
C +Q C P TC S Q + GC+CPEG + + G+ V + C C
Sbjct: 4762 CPSHREYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC 4817
Query: 1871 L-VDGARYWPGQRIKADCQLCICQDG------RPRRCRLNP--DCAVDCGW--SSWSPWA 1919
+ D G+ + DC+ C+C +G +P+RC P C D + + +P
Sbjct: 4818 VGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD 4877
Query: 1920 KCLG----PCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEG---CEHQGQ 1972
C C + + P G + + R C CE C H
Sbjct: 4878 TCCNITVCKCNTSLCK------EKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA 4931
Query: 1973 VHRVGERWHGGPCRVCQC--------LHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHC 2024
++ G + C+ C C L N+ A C+ SC G+ L+E GE C C
Sbjct: 4932 EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIA-CTHVPCNTSCSPGFELMEAPGECCKKC 4990
Score = 52.4 bits (124), Expect = 1e-05
Identities = 49/166 (29%), Positives = 62/166 (37%), Gaps = 31/166 (18%)
Query: 4602 QQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNG 4661
QQ C PG D+C S +S Q +GG WR A LC C +G
Sbjct: 251 QQDRCRCPGG--DTCVCSTVAEFSR-QCSHAGGRPGNWRTA-TLCPKTCPGNLVYLE-SG 305
Query: 4662 GPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQL---VQDGRCV 4718
PC DT L+ ++ C D GC CP G + + D CV
Sbjct: 306 SPC-----MDTCSHLEVSSLCEEHRMD--------------GCFCPEGTVYDDIGDSGCV 346
Query: 4719 PISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
P+S C C L + P Q + DC+ C C VC CP
Sbjct: 347 PVSQCHCRLHGHLYT----PGQEITNDCEQCVCNAGRWVCKDLPCP 388
Score = 52.4 bits (124), Expect = 1e-05
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 10/107 (9%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQA---GGCIPPEEC 4478
+C + GSPC C+ LC++ GC+CP+G + GC+P +C
Sbjct: 294 TCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR--MDGCFCPEGTVYDDIGDSGCVPVSQC 351
Query: 4479 NCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPL 4525
+C G PG + C++C C G C C G L
Sbjct: 352 HC-----RLHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPGTCAL 393
Score = 50.4 bits (119), Expect = 4e-05
Identities = 95/391 (24%), Positives = 127/391 (32%), Gaps = 79/391 (20%)
Query: 4713 QDGRCVPISSCRCGLPSAN--ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWS 4770
Q G C +S C LPS ++ E A Q + D C PH P
Sbjct: 4621 QCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHC-------PHSSSTTKRP-- 4671
Query: 4771 AWSSCSAPCGGGTMERHRTCEGGPGV--------APCQAQDTEQR--QECNLQPC----- 4815
+ + P GGG H+ C P A C A Q C C
Sbjct: 4672 ---AVTVP-GGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS 4727
Query: 4816 -PECPPGQVLSA-CATSCPCLCWHLQPGAICVQEPCQP-----GCG------CPGGQLLH 4862
EC Q +A CA CL W C+ E C CG C
Sbjct: 4728 SLECASLQAYAALCAQQNICLDWRNHTHGACLVE-CPSHREYQACGPAEEPTCKSSSSQQ 4786
Query: 4863 NGTCVPPTACPCTQHSLPW--GLTLTLEEQAQELPP------GTVLTRNCTRCVC--HGG 4912
N T V C C + ++ + G + ++ P G +C CVC G
Sbjct: 4787 NNT-VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGS 4845
Query: 4913 AFSCSLVDCQVPPG----ETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQP 4968
C C P E +A E+ + C N T + N S + VC
Sbjct: 4846 GIICQPKRCSQKPVTHCVEDGTYLAT-EVNPADTCC---NITVCKCNTSLCKEKPSVCPL 4901
Query: 4969 GH---FRSQAGPCVPEDHCE----CWHLGRPHLPGSE-WQEACESCLC--------LSGR 5012
G + G C P CE C H + PGS + C+ C+C L
Sbjct: 4902 GFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNV 4961
Query: 5013 PVCTQHCSPLTCAQGEEMVLEPGSCCPSCRR 5043
CT +C+ G E++ PG CC C +
Sbjct: 4962 IACTHVPCNTSCSPGFELMEAPGECCKKCEQ 4992
Score = 48.9 bits (115), Expect = 1e-04
Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 19/103 (18%)
Query: 3090 CPRDKQWLDCAQGPA---------SCAELSAPRGTNQT-CHPGCHCPSGMLLLNNV-CVP 3138
C K +DC+ A SC L+A G T C GC CP G++ CV
Sbjct: 759 CTAPKIHMDCSNLTALATSKPRALSCQTLAA--GYYHTECVSGCVCPDGLMDDGRGGCVV 816
Query: 3139 TQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAE 3181
++CPC H LY G+ + C C+C G W C +
Sbjct: 817 EKECPCVHNNDLYSSGAKIKVDCNTCTCKRG------RWVCTQ 853
Score = 48.1 bits (113), Expect = 2e-04
Identities = 69/287 (24%), Positives = 103/287 (35%), Gaps = 69/287 (24%)
Query: 2474 GECLSAERRCDLRPDCQ-DGSDEDGCVDCVLAPWSVWSSCSRSCGLGLTFQRQELLRPPL 2532
G C SA + C+ D + DC+ A S ++ + G+ L R+ + +
Sbjct: 599 GRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDV 658
Query: 2533 PGGSCPRDR---FRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKN 2589
GSCP + + +C Q C S+S H C++
Sbjct: 659 --GSCPNSQVFLYNLTTC-QQTCR--------------SLSEADSH------CLEGFAPV 695
Query: 2590 GGAPCPGAS--QERAPC-GLQPCS---GGTDCELGRVYVSAD---LCQKGL-----VPPC 2635
G CP + E+ C L CS G E G V V + +C+ G +
Sbjct: 696 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 755
Query: 2636 PPSCLDPKANRSCSG------------------------HCVEGCRCPPGLLLHDTR--C 2669
SC PK + CS CV GC CP G L+ D R C
Sbjct: 756 GQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG-LMDDGRGGC 814
Query: 2670 LPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPC 2716
+ ECPC+ +L G + +C+ C C++G +C C C
Sbjct: 815 VVEKECPCVHNNDLYSSGAKIKV-DCNTCTCKRGRWVCTQAVCHGTC 860
Score = 46.6 bits (109), Expect = 6e-04
Identities = 46/200 (23%), Positives = 72/200 (36%), Gaps = 15/200 (7%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIV-CQDDQVCQKGCRCPKGS-LEQDGGCVPIGHCDC 4119
CP + C + C L E C + GC CP + L++ G CVP+ C C
Sbjct: 661 CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC 720
Query: 4120 TDAQGHSWAPGSQHQDACNNCSCQAGQLSC-----TAQPC-PPPTHCAWSHWSAWS---P 4170
+G G C C+ G+L C Q C P H S+ +A + P
Sbjct: 721 YH-RGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKP 779
Query: 4171 CSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQ 4230
+ SC SG P+ + + + CP C+ + G + ++
Sbjct: 780 RALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP--CVHNNDLYSSG-AKIK 836
Query: 4231 GECQRCSCTPEGVICEDTEC 4250
+C C+C +C C
Sbjct: 837 VDCNTCTCKRGRWVCTQAVC 856
Score = 44.7 bits (104), Expect = 0.002
Identities = 35/120 (29%), Positives = 48/120 (40%), Gaps = 15/120 (12%)
Query: 3290 YCEGPRAQGEVCQA--LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWR--CQPGCY 3345
+C R G+ C A + +N TA+ ++ P SC L + C GC
Sbjct: 748 HCRQIRLIGQSCTAPKIHMDCSNLTALATSK------PRALSCQTLAAGYYHTECVSGCV 801
Query: 3346 CPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
CP G + G CV C C+ + GA++ CN CTC GR CT C
Sbjct: 802 CPDGLMDDGRGG-CVVEKECPCVH--NNDLYSSGAKIKVD--CNTCTCKRGRWVCTQAVC 856
Score = 44.3 bits (103), Expect = 0.003
Identities = 49/205 (23%), Positives = 70/205 (34%), Gaps = 35/205 (17%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGC-VPIGH 4116
C CP+ E C C Q++ V +GC CP+G++ G V +
Sbjct: 4758 CLVECPSHREYQACGPAEEPTCKSSSSQ---QNNTVLVEGCFCPEGTMNYAPGFDVCVKT 4814
Query: 4117 CDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQP--C--PPPTHCAWSHW---SAWS 4169
C C G + C NC C G QP C P THC + +
Sbjct: 4815 CGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVN 4874
Query: 4170 PCSHSCGPRGQQSRFRSSTSGSWAPECREEQS--------QSQPCPQPSCP-------PL 4214
P C + + +TS C+E+ S +S+ P CP +
Sbjct: 4875 PADTCC----NITVCKCNTS-----LCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGV 4925
Query: 4215 CLQGTRSRTLGDSWLQGECQRCSCT 4239
C+ G G +CQ C CT
Sbjct: 4926 CVHGNAEYQPGSPVYSSKCQDCVCT 4950
Score = 42.0 bits (97), Expect = 0.016
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 5/88 (5%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQM-VTTTPIPQMEARTLPPGMAAVTVVPP 2368
PP +P+ PT T P P + P + +TTTP P T P + T P
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP----SPTTTPS 1706
Query: 2369 HPVTPATPAGQSVAPGPFPPVQCGPGQT 2396
P+T T + P P P P T
Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Score = 40.8 bits (94), Expect = 0.035
Identities = 40/158 (25%), Positives = 52/158 (32%), Gaps = 48/158 (30%)
Query: 3670 RRCARPPCPGPARQSRTCST-----QVCREAG---------------CPAGRLYRECQPG 3709
R C + C P + CST + C AG CP +Y E G
Sbjct: 248 RACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLES--G 305
Query: 3710 EGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRL---AC--VQECPCVLTAWLLQELG 3764
C +C+H+ C E +GC CPEGT + C V +C C L
Sbjct: 306 SPCMDTCSHLEVSSLC-EEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRL--------- 355
Query: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
G GQ + C C C G+ C
Sbjct: 356 -----------HGHLYTPGQEITNDCEQCVCNAGRWVC 382
Score = 40.8 bits (94), Expect = 0.035
Identities = 28/87 (32%), Positives = 32/87 (36%), Gaps = 5/87 (5%)
Query: 3088 GMCPRDKQWL----DCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLL-LNNVCVPTQDC 3142
G CP + +L C Q S +E + GC CP L CVP C
Sbjct: 659 GSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKC 718
Query: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSG 3169
C H G G VVR E C C G
Sbjct: 719 SCYHRGLYLEAGDVVVRQEERCVCRDG 745
Score = 40.0 bits (92), Expect = 0.060
Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 32/108 (29%)
Query: 3697 CPAGRLYRECQPGEG--CPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRL---ACVQEC 3751
CP+ R Y+ C P E C S + V EGC CPEGT + CV+ C
Sbjct: 4762 CPSHREYQACGPAEEPTCKSSSSQQNNTV------LVEGCFCPEGTMNYAPGFDVCVKTC 4815
Query: 3752 PCVLTAWLLQELGATIGDPGQPLGPGD-ELDSGQTLRTSCGNCSCAHG 3798
CV GP + + G+ C NC C G
Sbjct: 4816 GCV--------------------GPDNVPREFGEHFEFDCKNCVCLEG 4843
Score = 39.3 bits (90), Expect = 0.10
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 19/95 (20%)
Query: 862 CPLGLLWDPEGQCVPPSLCP---------CQLGARRYAPGSATMK-ECNRCICQER---- 907
CPLG ++ + + VP CP C G Y PGS +C C+C ++
Sbjct: 4899 CPLG--FEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNN 4956
Query: 908 GLWNCTA-RHCPSQAFCPR--ELVYAPGACLLTCD 939
L N A H P C EL+ APG C C+
Sbjct: 4957 TLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCE 4991
Score = 38.9 bits (89), Expect = 0.13
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 2/76 (2%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPH 2369
PP + T P T P P P + TTTP P T PP T PP
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP--PTTTPSPPT 1661
Query: 2370 PVTPATPAGQSVAPGP 2385
TP+ P + P P
Sbjct: 1662 TTTPSPPITTTTTPPP 1677
Score = 38.1 bits (87), Expect = 0.23
Identities = 23/76 (30%), Positives = 27/76 (35%), Gaps = 2/76 (2%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPH 2369
PP T PT T + P P + TTTP P PP T PP
Sbjct: 1541 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP--TITTTTPPP 1598
Query: 2370 PVTPATPAGQSVAPGP 2385
TP+ P + P P
Sbjct: 1599 TTTPSPPTTTTTTPPP 1614
Score = 38.1 bits (87), Expect = 0.23
Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 21/109 (19%)
Query: 2310 PPGQESPTSPTETRPV---------SPGPASGVPHHGESVQMVTTTPIPQMEARTLP--- 2357
PP +P+SP T P SP P + TTTP P T P
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Query: 2358 ----PGMAAVTVVPP----HPVTPATPAGQSVAPGPFPPVQCGPGQTPC 2398
P +T +PP P+T TP S+ P F P TPC
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLT-TTPLPPSITPPTFSPFSTTTPTTPC 1782
Score = 37.7 bits (86), Expect = 0.30
Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 21/124 (16%)
Query: 3326 CPRSCDDLV----HCVWRCQP--GCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPG 3379
C ++C L HC+ P GC CP L G CV CSC +H G
Sbjct: 674 CQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGR-CVPLAKCSC--------YHRG 724
Query: 3380 ARLARPDGC----NHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRAC 3435
L D C C +GRL+C + + G C + M S+ RA
Sbjct: 725 LYLEAGDVVVRQEERCVCRDGRLHCRQI--RLIGQSCTAPKIHMDCSNLTALATSKPRAL 782
Query: 3436 ACPT 3439
+C T
Sbjct: 783 SCQT 786
Score = 37.7 bits (86), Expect = 0.30
Identities = 25/88 (28%), Positives = 31/88 (35%), Gaps = 2/88 (2%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPH 2369
PP T PT T + P P + TTTP P PP T PP
Sbjct: 1620 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP--ITTTTTPPP 1677
Query: 2370 PVTPATPAGQSVAPGPFPPVQCGPGQTP 2397
TP++P + +P P TP
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTP 1705
Score = 37.4 bits (85), Expect = 0.39
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPH 2369
PP +P+ PT T P P P + TTTP P PP A+ T +PP
Sbjct: 1464 PPPTTTPSPPT-TTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP--ASTTTLPP- 1519
Query: 2370 PVTPATPAGQSVAPGP 2385
TP+ P + P P
Sbjct: 1520 TTTPSPPTTTTTTPPP 1535
Score = 37.4 bits (85), Expect = 0.39
Identities = 27/86 (31%), Positives = 33/86 (38%), Gaps = 10/86 (11%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPI-PQMEARTLPPGMA-----AV 2363
PP + T P T P P + P + TTTPI P TLPP
Sbjct: 1588 PPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1647
Query: 2364 TVVPPHPVTPATPAGQSVAPGPFPPV 2389
T PP TP+ P + P PP+
Sbjct: 1648 TTTPPPTTTPSPPTTTT----PSPPI 1669
Score = 37.0 bits (84), Expect = 0.51
Identities = 53/234 (22%), Positives = 76/234 (32%), Gaps = 67/234 (28%)
Query: 1732 CPGPEHQSQACFTAA--CPVDGEWSTWSPWSVCSEPCRGTMTRQRQC----HSPQNGGRT 1785
C +H+S FT V E + W + C T C H +
Sbjct: 992 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPDVSTNPEPCSLNPHRRSWAEKQ 1050
Query: 1786 CAALPGGL----HSTRQTKP----CPQDGCPNAT-------CSGELMF-QPCAP------ 1823
C+ L + HS KP C D C T CS + Q C
Sbjct: 1051 CSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF 1110
Query: 1824 ------CPLTCDDISGQVTCPPDW---PCGS---------------------PGCW--CP 1851
CP+ CD + C +W PCG+ GC+ CP
Sbjct: 1111 WRTPDLCPIFCDYYNPPHEC--EWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCP 1168
Query: 1852 EGQVLGSEGW--CVWPRQCPCLVDGARYWPGQRIKAD--CQLCICQDGRPRRCR 1901
+ + + E CV +C C V+ Y PG + + C+ C+C + CR
Sbjct: 1169 KDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1222
Score = 37.0 bits (84), Expect = 0.51
Identities = 27/93 (29%), Positives = 33/93 (35%), Gaps = 6/93 (6%)
Query: 2311 PGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPI-PQMEARTLPPGMA-----AVT 2364
P + T P T P P + P + TTTPI P TLPP T
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1569
Query: 2365 VVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTP 2397
PP TP+ P + +P P TP
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602
Score = 37.0 bits (84), Expect = 0.51
Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 30/113 (26%)
Query: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLC--QDLPPCQP------------GCYCPK 4463
C++ + + H G+ C C +H +Q C + P C+ GC+CP+
Sbjct: 4741 CAQQNICLDWRNHTHGA-CLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPE 4799
Query: 4464 GLLEQAGG---CIPPEECNCWHTSAAGAGMTLAP---GDRLQLGCKECECRRG 4510
G + A G C+ + C C G P G+ + CK C C G
Sbjct: 4800 GTMNYAPGFDVCV--KTCGC-------VGPDNVPREFGEHFEFDCKNCVCLEG 4843
Score = 36.6 bits (83), Expect = 0.66
Identities = 26/90 (28%), Positives = 30/90 (33%), Gaps = 3/90 (3%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGM---AAVTVV 2366
PP + T P T P P P + TTTP P T PP + T
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1545
Query: 2367 PPHPVTPATPAGQSVAPGPFPPVQCGPGQT 2396
P P T T + P P P P T
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1575
Score = 36.6 bits (83), Expect = 0.66
Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 10/76 (13%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPH 2369
PP +P+ PT T P + +P TTTP P T PP T PP
Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLP--------PTTTPSPPPTTTTTPP--PTTTPSPPT 1582
Query: 2370 PVTPATPAGQSVAPGP 2385
TP+ P + P P
Sbjct: 1583 TTTPSPPTITTTTPPP 1598
Score = 36.6 bits (83), Expect = 0.66
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 10/90 (11%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGM---AAVTVV 2366
PP +P+ PT T P P + P TTTP P T PP + T
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTP-------PPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624
Query: 2367 PPHPVTPATPAGQSVAPGPFPPVQCGPGQT 2396
P P T T + P P P P T
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654
Score = 36.6 bits (83), Expect = 0.66
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 6/90 (6%)
Query: 2313 QESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTL----PPGMAAVTVVPP 2368
Q P + T T P++ S P + Q +T P E+ TL PP + + PP
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP 4253
Query: 2369 H-PVTPATPAGQSVAPGPFPPVQCGPGQTP 2397
P P T +G P P P TP
Sbjct: 4254 STPTAPTTTSGGHTLSPP-PSTTTSPPGTP 4282
Score = 36.2 bits (82), Expect = 0.87
Identities = 26/88 (29%), Positives = 31/88 (35%), Gaps = 4/88 (4%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAAVTVVPPH 2369
PP + T P T P P + P + TTTP P T P T PP
Sbjct: 1440 PPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSP---PTTTPSPPTTTTTTPPP 1496
Query: 2370 PVTPATPAGQSVAPGPFPPVQCGPGQTP 2397
TP+ P + P P P TP
Sbjct: 1497 TTTPSPPTTTPITP-PASTTTLPPTTTP 1523
Score = 35.8 bits (81), Expect = 1.1
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 20/144 (13%)
Query: 3090 CPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDCPCAH 3146
CP +++ C + S+ + N GC CP G + +VCV T C C
Sbjct: 4762 CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVG 4819
Query: 3147 EGHLYPP-GSTVVRPCENCSCV---SGLIA---NCSSWP---CAE-GEPTWSPWTPWSQC 3195
++ G C+NC C+ SG+I CS P C E G + P C
Sbjct: 4820 PDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Query: 3196 SASCGPARCH-RHRFCARSPSAVP 3218
C C C PS P
Sbjct: 4880 ---CNITVCKCNTSLCKEKPSVCP 4900
Score = 35.4 bits (80), Expect = 1.5
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 21/106 (19%)
Query: 4693 VQCLQGPCRPGCRCPPGQLVQDG---RCVPISSCRCGLPSANASWELAPAQAVQLD--CQ 4747
V L+G C P RCP + + + +CV C C + + P +V + C+
Sbjct: 1157 VSYLEG-CYP--RCPKDRPIYEEDLKKCVTADKCGCYVEDTH----YPPGASVPTEETCK 1209
Query: 4748 NCTCVNES-LVCPHQECPVL-----GPWSAWSSCSAPCGGGTMERH 4787
+C C N S +VC +E +L G + W C GT+E+H
Sbjct: 1210 SCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGP---NGTVEKH 1252
Score = 34.7 bits (78), Expect = 2.5
Identities = 26/88 (29%), Positives = 30/88 (34%), Gaps = 11/88 (12%)
Query: 2298 WPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLP 2357
WP + T P SP PT T + P P TTTP P T P
Sbjct: 1390 WPMDKCITTPSPPTTTPSPP-PTSTTTLPPTTTPSPP------TTTTTTPPPT----TTP 1438
Query: 2358 PGMAAVTVVPPHPVTPATPAGQSVAPGP 2385
T PP TP+ P + P P
Sbjct: 1439 SPPITTTTTPPPTTTPSPPISTTTTPPP 1466
Score = 33.9 bits (76), Expect = 4.3
Identities = 58/254 (22%), Positives = 87/254 (34%), Gaps = 73/254 (28%)
Query: 3528 DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC 3587
+C + CG +C+ S Q + C CP G ++ P C
Sbjct: 4761 ECPSHREYQACGPAEEPTCKSSSS----QQNNTVLVEGCFCPEGTMNY-----APGFDVC 4811
Query: 3588 QYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCV---AGIL----QCQEVP 3640
G +G P+N R G F C NC C+ +GI+ +C + P
Sbjct: 4812 VKTCGCVG-PDNVPREFGEHFEF------------DCKNCVCLEGGSGIICQPKRCSQKP 4858
Query: 3641 --DCPDPGVW--SSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCRE-- 3694
C + G + + P + C C C C+T +C+E
Sbjct: 4859 VTHCVEDGTYLATEVNPADTC--------------CNITVC--------KCNTSLCKEKP 4896
Query: 3695 AGCPAG-RLYRECQPGEGCPF-------SCAH--VTQQVG--CFSEGCEEGCHCPEGTFQ 3742
+ CP G + + PG CPF C H Q G +S C++ C C +
Sbjct: 4897 SVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQD-CVCTDKVDN 4955
Query: 3743 HRLACVQEC---PC 3753
+ L V C PC
Sbjct: 4956 NTLLNVIACTHVPC 4969
Score = 33.5 bits (75), Expect = 5.6
Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 13/121 (10%)
Query: 3119 CHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTV--VRPCENCSCVSGLIAN 3173
C+P CP + CV C C E YPPG++V C++C C +
Sbjct: 1163 CYP--RCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVV 1220
Query: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTV---APLPLPATP 3230
C EG+ CGP F S + PST+ + LP TP
Sbjct: 1221 CRP---EEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTP 1277
Query: 3231 T 3231
T
Sbjct: 1278 T 1278
Score = 33.1 bits (74), Expect = 7.3
Identities = 23/80 (28%), Positives = 28/80 (35%), Gaps = 11/80 (13%)
Query: 2310 PPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTLPPGMAA----VTV 2365
PP + T P T P P + P TTTP P + T PP T
Sbjct: 1424 PPTTTTTTPPPTTTPSPPITTTTTPPP-------TTTPSPPISTTTTPPPTTTPSPPTTT 1476
Query: 2366 VPPHPVTPATPAGQSVAPGP 2385
P TP+ P + P P
Sbjct: 1477 PSPPTTTPSPPTTTTTTPPP 1496
Score = 33.1 bits (74), Expect = 7.3
Identities = 13/41 (31%), Positives = 25/41 (60%), Gaps = 5/41 (12%)
Query: 1529 PLPSLPTPPASTLPGPSP-----GSLDTASSPLASASPAPP 1564
P+ + P+PP +T+ PSP + T ++P ++ +P+PP
Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPP 1724
Score = 32.7 bits (73), Expect = 9.6
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 9/81 (11%)
Query: 4942 QTCLEMNATKTQSNCSSARASGCV--CQPGH--FRSQAGPCVPEDHCECWHLGRPHLPGS 4997
+TC +N SN S + GC C + CV D C C+ + PG+
Sbjct: 1143 ETCRTINGI--HSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1200
Query: 4998 E--WQEACESCLCL-SGRPVC 5015
+E C+SC+C S + VC
Sbjct: 1201 SVPTEETCKSCVCTNSSQVVC 1221
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 546 bits (1408), Expect = e-154
Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249
C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
Query: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
+G +E+ + A V+ G V ++ LQ L ++++ + D +
Sbjct: 139 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364
+ I + EL G T GLCG N P+DD + G L F +SW+ P G +
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
C PG ++ + C LL PF CHA VSP + +C C
Sbjct: 256 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 307
Query: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481
G C A Y +ACA+ ++ WR C C Y++C++
Sbjct: 308 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CP SC SC + CV GC CP GL + CV A CPC + Y PG
Sbjct: 361 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 415
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L +
Sbjct: 416 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 473
Query: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652
G + L++ C G+C+ ++SV L + L +G VL+ Q +P +
Sbjct: 474 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 533
Query: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711
+RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P
Sbjct: 534 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 593
Query: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771
G E++ F + ++ P + L PC H Q +++ AC++L +F C
Sbjct: 594 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 652
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830
+ P++ +C C C G CLC L+ YA C + G +R + C + C
Sbjct: 653 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 710
Query: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879
+EY C CG+ C PE CG G CV GC CP D + CVP +
Sbjct: 711 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 770
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935
C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L
Sbjct: 771 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 827
Query: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988
TC+ N S A GC CP G + + C P+ CPC G+ Y P
Sbjct: 828 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047
+ C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S +
Sbjct: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 947
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106
F+V +N+ C +SG+ C K +++ + +++ V + P+ + +
Sbjct: 948 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1000
Query: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + +
Sbjct: 1001 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1060
Query: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224
+ SW + CP+ D C +N R +A+ C LL +F +CH V
Sbjct: 1061 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1119
Query: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+
Sbjct: 1120 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
Score = 255 bits (651), Expect = 9e-67
Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
L CT HC +AF E + C +C ++ DGC CP G + D C
Sbjct: 340 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
Query: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG
Sbjct: 396 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 455
Query: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082
+T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G
Sbjct: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 515
Query: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140
+ + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++
Sbjct: 516 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198
GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 633
Query: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
++ C L +F C A + P ++E C DAC C CLC+ +A YA C R
Sbjct: 634 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 689
Query: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311
HG V +R++ C+L CE + Y C C TC + PE G CVEG
Sbjct: 690 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 749
Query: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C CP T L A C+ C C + +PPG G+C C++G C
Sbjct: 750 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 802
Score = 214 bits (546), Expect = 1e-54
Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
+C P L C + G+ P N R + + G R C+A G H TFD
Sbjct: 32 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 91
Query: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081
GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+
Sbjct: 92 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 149
Query: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141
+ VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G
Sbjct: 150 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 207
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195
GLCG+ + D +DL + G L HSW+ P P LP P + N
Sbjct: 208 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 267
Query: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
+C ALL+P F CHA V P C D C S GD C A+A YA
Sbjct: 268 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 325
Query: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312
CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC
Sbjct: 326 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 382
Query: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
+CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C
Sbjct: 383 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 432
Score = 146 bits (369), Expect = 5e-34
Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)
Query: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144
W +R C HC E KA C A C +A ++ ++ C P
Sbjct: 336 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 386
Query: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199
G + DG A C + + PGS G+ A C+
Sbjct: 387 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 445
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250
H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++
Sbjct: 446 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
Query: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305
+ L QAG+V + Q ++P ++ + LS +L + +GV V DR G
Sbjct: 506 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 561
Query: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365
+ + VD T GLCG +NG +DDF+ P G FGNSW+ L A
Sbjct: 562 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 614
Query: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
PL D HL+A + V C L F C A +SP Y E C C
Sbjct: 615 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480
Q +CAT A Y C RRH + R R P C C + YS CV+
Sbjct: 670 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 718
Query: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531
C +C EA G G ++ R+ECV GC CP + + LCVP C C++
Sbjct: 719 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 778
Query: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567
Y PGD+ C C+DG C A C G
Sbjct: 779 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 814
Score = 98.2 bits (243), Expect = 2e-19
Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)
Query: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061
W C + RC +VTFDG Y+L + + TV + G
Sbjct: 2033 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2087
Query: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116
L V L T + H + R VTV+ V PP + G + G ++ T
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2145
Query: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172
+ + W ++V+ S + + GLCG DGDA+NDL + G + AE A
Sbjct: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205
Query: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225
SW++ G P C A C L+ + F+ CH VPP+
Sbjct: 2206 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2256
Query: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
E + D C A+ Y C + + WR + C C Y+AC
Sbjct: 2257 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2310
Query: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333
C P TC + P HCQV+ EGC C EGT+L H C+ A C C
Sbjct: 2311 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2368
Query: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357
W P +++ D G +C C
Sbjct: 2369 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
Query: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C + CE L P C G L QE+ C + CD D C E P
Sbjct: 2429 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2480
Query: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465
C + Q +T G + C CGD CP + C +G L
Sbjct: 2481 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2521
Score = 85.1 bits (209), Expect = 2e-15
Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913
C +LA C + TQ CT C E + C CP C +
Sbjct: 316 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 369
Query: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973
++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG
Sbjct: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 428
Query: 2974 KMACTSERCPVAC 2986
K C++ CP C
Sbjct: 429 KWECSTAVCPAEC 441
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)
Query: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207
Q R S+H P A+ P + LA VG LW R C+ + + TFD
Sbjct: 1996 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2051
Query: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258
G H Y+L+ + D VH+ + GH +T +V I
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2110
Query: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317
N V L P +G ++ G +++L+ + L +G + +
Sbjct: 2111 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170
Query: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374
Q GLCG+ +G +D G G A A F +SW++P S + C
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2227
Query: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433
D P C +++ F CH V P + E +
Sbjct: 2228 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2264
Query: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489
Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ +
Sbjct: 2265 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
Query: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526
G + E C + GC C G + LC+P A C C
Sbjct: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 73.9 bits (180), Expect = 4e-12
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087
+R+C+ G P G R Q R C + C+ E + C CP C
Sbjct: 323 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 370
Query: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146
C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+
Sbjct: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 429
Query: 4147 LSCTAQPCP 4155
C+ CP
Sbjct: 430 WECSTAVCP 438
Score = 72.4 bits (176), Expect = 1e-11
Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)
Query: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576
+ W S C P + S L P A+ +++ + +P L+P+ EQ R
Sbjct: 606 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 665
Query: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626
C G P LC LC G AC SC+ S +SP
Sbjct: 666 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 715
Query: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684
C PC G C++ + E+C +GG
Sbjct: 716 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 738
Query: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742
D R +C++G C CPP + Q CVP + C C + P +
Sbjct: 739 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 786
Query: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+C C + + C P CP + +CS + R RTCE
Sbjct: 787 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 836
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858
+Q NL ++ + PC GC CP G
Sbjct: 837 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 859
Query: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918
L H C P CPCT W + +E PG + C CVC G+F C+L
Sbjct: 860 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 906
Query: 4919 VDC 4921
C
Sbjct: 907 HPC 909
Score = 70.9 bits (172), Expect = 3e-11
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C
Sbjct: 362 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 421
Query: 3163 NCSCVSGLIANCSSWPCA 3180
C+C SG W C+
Sbjct: 422 TCTCTSG------KWECS 433
Score = 70.9 bits (172), Expect = 3e-11
Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867
C + S C C C L C ++ C GC CP L CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925
P C C Q + PPG + C C G SC P
Sbjct: 767 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 813
Query: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
G+ + + +L L + E + SGC C G R +PE+
Sbjct: 814 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 872
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
C C G+ + PG + C +C+C G CT H TC
Sbjct: 873 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 913
Score = 70.1 bits (170), Expect = 5e-11
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)
Query: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466
W E P G T S C G E EA + +AC +Y
Sbjct: 241 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 298
Query: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
A+C D + G W C + +RAC+ + GRP G TQ R C +
Sbjct: 299 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 345
Query: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584
C + + + C CP SC P + C + C C CP G + +DG CV PA
Sbjct: 346 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 400
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
C C++ G+ + PG VV C+ CTC +G +C CP
Sbjct: 401 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 438
Score = 70.1 bits (170), Expect = 5e-11
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)
Query: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
C C +G + W A E R C P Q T+ RQ C + C E
Sbjct: 301 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 349
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875
+ C CP C P A CV C GC CP G + +G CV P CPC
Sbjct: 350 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 404
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
H + PPG+V+ +C C C G + CS C
Sbjct: 405 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 70.1 bits (170), Expect = 5e-11
Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)
Query: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167
S G C + C Q + A L E C W G+ ++ G C +C +
Sbjct: 845 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 899
Query: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226
S L P A +TC ++ HYRTFDG + F+G C +L+ +D
Sbjct: 900 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
Query: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278
+++V + C G R + +G ++ +GN S + L E +W +
Sbjct: 946 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
Query: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
+ LV + + D+ ++ + + GQ GLCG ++ ++ P
Sbjct: 1005 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1057
Query: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396
FG+SW AVE DP + +++ EP A+ C
Sbjct: 1058 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1102
Query: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
LL F CH V ++ CL C G Q G + CA+ ++Y C + +
Sbjct: 1103 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1157
Query: 457 IRWRKPGFCERLCP 470
+ WR P RLCP
Sbjct: 1158 VDWRTP----RLCP 1167
Score = 69.7 bits (169), Expect = 7e-11
Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846
C+AP G S C G D E PP + + L P + CS
Sbjct: 716 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 775
Query: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901
G PGD+ P H +D C+++ A CP +F + H +
Sbjct: 776 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 826
Query: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958
R C Q + G C GC CP GL H +C +CPC G+ Y G
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 886
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ C+ C C G CT C C
Sbjct: 887 QV-MSPCHTCVCQRGSFQCTLHPCASTC 913
Score = 68.9 bits (167), Expect = 1e-10
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373
P PC + + C L+ C++ L T C S C ++W
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 315
Query: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433
CR L + A A+AG P R C + +C E + F ++ C
Sbjct: 316 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 358
Query: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491
+ C C S C D C GCYCP GL+ + GGC+ P EC C +H G
Sbjct: 359 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 409
Query: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519
PG ++ C C C G+ C++ C
Sbjct: 410 YPPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 68.9 bits (167), Expect = 1e-10
Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)
Query: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351
LP +C A + EYSPC PC R+C DL C GC CPP
Sbjct: 700 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 757
Query: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
L + +CV CSC G + PG + HC C +G ++C P
Sbjct: 758 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 810
Query: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466
CP + + CS SR R C PC +G A G +AC
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
CP + P SPC C+ CQ
Sbjct: 871 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 900
Query: 3523 STQCTDCGGGQSLHPCGQPC 3542
S QCT LHPC C
Sbjct: 901 SFQCT-------LHPCASTC 913
Score = 66.6 bits (161), Expect = 6e-10
Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)
Query: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
PC +C +H + C R P R + C C + PC PC
Sbjct: 674 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 720
Query: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592
R+CQDL+ C G G C C CP +Q LCVP C C +Q
Sbjct: 721 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 776
Query: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
G+ PG+ +C C G++ C
Sbjct: 777 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 803
Query: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710
+R P A CPAG+++ C
Sbjct: 804 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 826
Query: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764
+C + + G C GC CP+G +H AC +ECPC W
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCT---W------ 877
Query: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+ PGD++ S C C C G C+L C +G
Sbjct: 878 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 917
Score = 66.6 bits (161), Expect = 6e-10
Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)
Query: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533
+S+ EA+ E + CV E C R + G L + HCP R
Sbjct: 1957 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2016
Query: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593
+ G VR + C W CA C++ D ++TFDG + + + Y L
Sbjct: 2017 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2066
Query: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642
Q + + +L+ + + G CL V L TH+ R + V V+ Q
Sbjct: 2067 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702
V P + G + +++L Q+ W S + + Q GLCG
Sbjct: 2123 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2181
Query: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759
+ +D G V A F +QV S+L S T + + A C
Sbjct: 2182 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2232
Query: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812
+ ++ + F CHR V E F ++R V C L+ Y C +
Sbjct: 2233 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2285
Query: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863
WR CP +C Y+ C AC + C PE C LG GC C
Sbjct: 2286 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2342
Query: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917
G + C+P + C C +G R ++++ C + CQ C
Sbjct: 2343 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2402
Query: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964
PS PR L + A LL P C G+ C C PG LL
Sbjct: 2403 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2453
Query: 965 ----DERCVPPDLCPC 976
++ C P C C
Sbjct: 2454 THFQEDSCCPSYSCEC 2469
Score = 64.7 bits (156), Expect = 2e-09
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338
+ L +Y G Q + CT + Y+ C CP SC CV
Sbjct: 317 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 376
Query: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
C GCYCP G + G CV P C C G + PG+ + + CN CTC G+
Sbjct: 377 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 430
Query: 3399 NCTDLPCP 3406
C+ CP
Sbjct: 431 ECSTAVCP 438
Score = 64.3 bits (155), Expect = 3e-09
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)
Query: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105
C+ A CPAG V C++ R C + C GC CP+G L
Sbjct: 802 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 861
Query: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
C C CT +G + PG Q C+ C CQ G CT PC
Sbjct: 862 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
Score = 63.9 bits (154), Expect = 4e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)
Query: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639
VD PP G + P G+ C C G+V+V+ L +C
Sbjct: 778 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 835
Query: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697
N S S G C+ GC CP GLL H C ECPC + +PG ++ C
Sbjct: 836 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 894
Query: 2698 CVCEKGELLCQPGGCPLPC 2716
CVC++G C C C
Sbjct: 895 CVCQRGSFQCTLHPCASTC 913
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)
Query: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756
P PC + QG +C L C + S FTA+C D G+ +TW
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 315
Query: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813
CR R C P G RT Q + C A
Sbjct: 316 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 354
Query: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
E + A CP +C + +C GC+CP G + +G CV P +CPC
Sbjct: 355 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 406
Query: 1874 GARYWPGQRIKADCQLCICQDGR 1896
G Y PG +K DC C C G+
Sbjct: 407 GTLYPPGSVVKEDCNTCTCTSGK 429
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S +
Sbjct: 361 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 416
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G+ C CP C
Sbjct: 417 KEDCNTCTCTSGKWECSTAVCPAEC 441
Score = 62.0 bits (149), Expect = 1e-08
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125
G+ C P CP + +++C+ ELS R Q C GC C
Sbjct: 798 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 856
Query: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA
Sbjct: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 910
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513
PC GC CP+GLL C PEEC C G PGD++ C C C+RG
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 903
Query: 4514 CTSQGC 4519
CT C
Sbjct: 904 CTLHPC 909
Score = 60.5 bits (145), Expect = 4e-08
Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)
Query: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751
C A +SP PC RTC + C G G + C ACP D
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 756
Query: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
T + V C CH G +L G H C
Sbjct: 757 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 806
Query: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859
P A C +F C+ TC+ ++ PC S GC CP+G + +
Sbjct: 807 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 865
Query: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C
Sbjct: 866 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 913
Score = 58.2 bits (139), Expect = 2e-07
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091
CA H A LC + +P C C A E C C R C DL C D
Sbjct: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
Query: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142
C +GC CP + Q CVP C C QG + PG + +C C
Sbjct: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 795
Query: 4143 QAGQLSC----TAQPCP 4155
+ G +SC A CP
Sbjct: 796 KDGVMSCDSRAPAAACP 812
Score = 53.9 bits (128), Expect = 4e-06
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)
Query: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734
+C CP SC R C+ C GC CP G + +DG CV + C C
Sbjct: 356 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 408
Query: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
P V+ DC CTC + C CP
Sbjct: 409 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 438
Score = 51.2 bits (121), Expect = 3e-05
Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)
Query: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863
CP C AC T+C P C Q G + +P CQ GC C G +LH +
Sbjct: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
Query: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
C+P C CT +P W +L+ Q Q P T++
Sbjct: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2397
Query: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970
VD P + GE+ L T CL Q+ C + C+PGH
Sbjct: 2398 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2452
Query: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029
Q C P CEC P L CE+ L P C Q +T G+
Sbjct: 2453 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2496
Query: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083
C C PE Q + LT RN T+ C L Q C + C
Sbjct: 2497 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2551
Query: 5084 STHVM----PEE--PYLQSQCDC 5100
T ++ P+ PY +CDC
Sbjct: 2552 GTALVEVWSPDRCCPYKSCECDC 2574
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
+R CA+ P G Q R C+ C+E Y EC CP SC H
Sbjct: 323 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 374
Query: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784
C +GC+CP G CV ECPC E T+ PG
Sbjct: 375 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 414
Query: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807
++ C C+C GK CS C
Sbjct: 415 VVKEDCNTCTCTSGKWECSTAVC 437
Score = 49.3 bits (116), Expect = 1e-04
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137
C K++ C A +C +L++P + C GC CP L ++CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P C C +G YPPG + + +C C G+++ S P A
Sbjct: 767 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 809
Score = 48.9 bits (115), Expect = 1e-04
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472
SC E+ C +PC C S + C DL C GC CP L QA C
Sbjct: 706 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527
+P +C+C G+ PGD C C+ G + C S+ P +
Sbjct: 766 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 815
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
W S+CS G ++ PC Q ++Q C G++ + C+
Sbjct: 608 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 652
Query: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888
+ + Q C ++ C+ G C L H A C +H LP L
Sbjct: 653 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 700
Query: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947
P L+ ++ C P G T Q +A E C ++
Sbjct: 701 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 737
Query: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006
++ C GC C P + +QA CVP + C C G + PG + C
Sbjct: 738 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065
C G C C G+ V C + + +C Q L L +G
Sbjct: 794 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 848
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
C +S C+ CP + +L +C C
Sbjct: 849 PC------LSGCA--CPQGLLRHGDACFLPEECPC 875
Score = 46.6 bits (109), Expect = 6e-04
Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)
Query: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269
CA P T A L +P CS C QG D G HC C
Sbjct: 750 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 796
Query: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325
G+ S CD P A CP NC+ +
Sbjct: 797 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 834
Query: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384
C + +L V C GC CP G L +G C P C C G+ + PG ++
Sbjct: 835 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 890
Query: 3385 PDGCNHCTCLEGRLNCTDLPC 3405
P C+ C C G CT PC
Sbjct: 891 P--CHTCVCQRGSFQCTLHPC 909
Score = 45.4 bits (106), Expect = 0.001
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108
C C + C C P+ C Q+GI+ D QV +GC C +G++
Sbjct: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
Query: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159
C+P C CTD+ G A G + + C CQA L C P P P
Sbjct: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2409
Query: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211
C + + P C G + AP CR + CP SC
Sbjct: 2410 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2468
Query: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254
P LC + S + G CT C D ++PE
Sbjct: 2469 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2514
Score = 44.7 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018
A GC C P + G CV C C G + PGS +E C +C C SG+ C+
Sbjct: 377 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
Query: 5019 CSPLTCA 5025
P C+
Sbjct: 436 VCPAECS 442
Score = 43.1 bits (100), Expect = 0.007
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679
V PC +C D + +C CVEGC CPP L DT+ C+P ++C C
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 775
Query: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707
+ + +P + + C C+ G + C
Sbjct: 776 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 802
Score = 35.4 bits (80), Expect = 1.5
Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)
Query: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898
+T +PC + R S C P ++ C T+ QPC A + C
Sbjct: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2287
Query: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
+ CP LC + C C P TC G+ P CQ+ G+
Sbjct: 2288 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2341
Query: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012
L ++ C+ K ACT S P A G W+ +L C C
Sbjct: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2393
Query: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059
T P G C P E+ E L P P G C + C G
Sbjct: 2394 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2449
Query: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117
+R T S +C P C + C +D+ + G + C G
Sbjct: 2450 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2509
Query: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174
P C + + N +C P C C P C + L+
Sbjct: 2510 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2556
Query: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205
WSP P+ C C RCH
Sbjct: 2557 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2583
Score = 34.7 bits (78), Expect = 2.5
Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)
Query: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677
CQ G++ P LDP+ HC EGC C G +L H C+P ++C C
Sbjct: 2319 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2366
Query: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715
+GE W + L C Q C+ + + GCP P
Sbjct: 2367 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
Score = 33.9 bits (76), Expect = 4.3
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPP---CQPGCYCPKGLLEQAGGCIPPEEC---NC 4480
+ + AC SPC C + C+D+P C P C P+ L E C+ E+C
Sbjct: 1338 WRYDACASPCFQTCRDPRAAS-CRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1396
Query: 4481 WHTSAAGAGMTLAPGDRL 4498
W + A TL P L
Sbjct: 1397 WVPTEALGNETLPPSQGL 1414
Score = 32.7 bits (73), Expect = 9.6
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344
++L S +P QLL GL P + ++P T PGP + V
Sbjct: 1727 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1768
Query: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402
TTP+ Q +A TLP + PV P TPA + A P G P +LG
Sbjct: 1769 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
Score = 32.7 bits (73), Expect = 9.6
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
Query: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582
C + C C P++CQD G + CQ GC + G L + LC+P
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2358
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFS 3609
A C C +MG+P + S S
Sbjct: 2359 AKCAC---TDSMGVPRALGETWNSSLS 2382
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 546 bits (1408), Expect = e-154
Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249
C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210
Query: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
+G +E+ + A V+ G V ++ LQ L ++++ + D +
Sbjct: 211 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364
+ I + EL G T GLCG N P+DD + G L F +SW+ P G +
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
C PG ++ + C LL PF CHA VSP + +C C
Sbjct: 328 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 379
Query: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481
G C A Y +ACA+ ++ WR C C Y++C++
Sbjct: 380 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CP SC SC + CV GC CP GL + CV A CPC + Y PG
Sbjct: 433 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 487
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L +
Sbjct: 488 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 545
Query: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652
G + L++ C G+C+ ++SV L + L +G VL+ Q +P +
Sbjct: 546 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 605
Query: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711
+RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P
Sbjct: 606 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 665
Query: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771
G E++ F + ++ P + L PC H Q +++ AC++L +F C
Sbjct: 666 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 724
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830
+ P++ +C C C G CLC L+ YA C + G +R + C + C
Sbjct: 725 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 782
Query: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879
+EY C CG+ C PE CG G CV GC CP D + CVP +
Sbjct: 783 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 842
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935
C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L
Sbjct: 843 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 899
Query: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988
TC+ N S A GC CP G + + C P+ CPC G+ Y P
Sbjct: 900 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047
+ C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S +
Sbjct: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 1019
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106
F+V +N+ C +SG+ C K +++ + +++ V + P+ + +
Sbjct: 1020 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1072
Query: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + +
Sbjct: 1073 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1132
Query: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224
+ SW + CP+ D C +N R +A+ C LL +F +CH V
Sbjct: 1133 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1191
Query: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+
Sbjct: 1192 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243
Score = 255 bits (651), Expect = 9e-67
Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
L CT HC +AF E + C +C ++ DGC CP G + D C
Sbjct: 412 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 467
Query: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG
Sbjct: 468 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 527
Query: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082
+T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G
Sbjct: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 587
Query: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140
+ + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++
Sbjct: 588 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198
GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 705
Query: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
++ C L +F C A + P ++E C DAC C CLC+ +A YA C R
Sbjct: 706 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 761
Query: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311
HG V +R++ C+L CE + Y C C TC + PE G CVEG
Sbjct: 762 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 821
Query: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C CP T L A C+ C C + +PPG G+C C++G C
Sbjct: 822 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 874
Score = 214 bits (546), Expect = 1e-54
Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
+C P L C + G+ P N R + + G R C+A G H TFD
Sbjct: 104 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 163
Query: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081
GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+
Sbjct: 164 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 221
Query: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141
+ VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G
Sbjct: 222 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 279
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195
GLCG+ + D +DL + G L HSW+ P P LP P + N
Sbjct: 280 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 339
Query: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
+C ALL+P F CHA V P C D C S GD C A+A YA
Sbjct: 340 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 397
Query: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312
CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC
Sbjct: 398 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 454
Query: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
+CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C
Sbjct: 455 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 504
Score = 146 bits (369), Expect = 5e-34
Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)
Query: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144
W +R C HC E KA C A C +A ++ ++ C P
Sbjct: 408 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 458
Query: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199
G + DG A C + + PGS G+ A C+
Sbjct: 459 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 517
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250
H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++
Sbjct: 518 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 577
Query: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305
+ L QAG+V + Q ++P ++ + LS +L + +GV V DR G
Sbjct: 578 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 633
Query: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365
+ + VD T GLCG +NG +DDF+ P G FGNSW+ L A
Sbjct: 634 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 686
Query: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
PL D HL+A + V C L F C A +SP Y E C C
Sbjct: 687 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480
Q +CAT A Y C RRH + R R P C C + YS CV+
Sbjct: 742 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 790
Query: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531
C +C EA G G ++ R+ECV GC CP + + LCVP C C++
Sbjct: 791 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 850
Query: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567
Y PGD+ C C+DG C A C G
Sbjct: 851 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 886
Score = 98.2 bits (243), Expect = 2e-19
Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)
Query: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061
W C + RC +VTFDG Y+L + + TV + G
Sbjct: 2105 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2159
Query: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116
L V L T + H + R VTV+ V PP + G + G ++ T
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2217
Query: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172
+ + W ++V+ S + + GLCG DGDA+NDL + G + AE A
Sbjct: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277
Query: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225
SW++ G P C A C L+ + F+ CH VPP+
Sbjct: 2278 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2328
Query: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
E + D C A+ Y C + + WR + C C Y+AC
Sbjct: 2329 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2382
Query: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333
C P TC + P HCQV+ EGC C EGT+L H C+ A C C
Sbjct: 2383 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2440
Query: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357
W P +++ D G +C C
Sbjct: 2441 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
Query: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C + CE L P C G L QE+ C + CD D C E P
Sbjct: 2501 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2552
Query: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465
C + Q +T G + C CGD CP + C +G L
Sbjct: 2553 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2593
Score = 85.1 bits (209), Expect = 2e-15
Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913
C +LA C + TQ CT C E + C CP C +
Sbjct: 388 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 441
Query: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973
++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG
Sbjct: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 500
Query: 2974 KMACTSERCPVAC 2986
K C++ CP C
Sbjct: 501 KWECSTAVCPAEC 513
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)
Query: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207
Q R S+H P A+ P + LA VG LW R C+ + + TFD
Sbjct: 2068 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2123
Query: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258
G H Y+L+ + D VH+ + GH +T +V I
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2182
Query: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317
N V L P +G ++ G +++L+ + L +G + +
Sbjct: 2183 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2242
Query: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374
Q GLCG+ +G +D G G A A F +SW++P S + C
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2299
Query: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433
D P C +++ F CH V P + E +
Sbjct: 2300 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2336
Query: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489
Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ +
Sbjct: 2337 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2396
Query: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526
G + E C + GC C G + LC+P A C C
Sbjct: 2397 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 73.9 bits (180), Expect = 4e-12
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087
+R+C+ G P G R Q R C + C+ E + C CP C
Sbjct: 395 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 442
Query: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146
C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+
Sbjct: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 501
Query: 4147 LSCTAQPCP 4155
C+ CP
Sbjct: 502 WECSTAVCP 510
Score = 72.4 bits (176), Expect = 1e-11
Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)
Query: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576
+ W S C P + S L P A+ +++ + +P L+P+ EQ R
Sbjct: 678 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 737
Query: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626
C G P LC LC G AC SC+ S +SP
Sbjct: 738 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 787
Query: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684
C PC G C++ + E+C +GG
Sbjct: 788 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 810
Query: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742
D R +C++G C CPP + Q CVP + C C + P +
Sbjct: 811 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 858
Query: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+C C + + C P CP + +CS + R RTCE
Sbjct: 859 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 908
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858
+Q NL ++ + PC GC CP G
Sbjct: 909 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 931
Query: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918
L H C P CPCT W + +E PG + C CVC G+F C+L
Sbjct: 932 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 978
Query: 4919 VDC 4921
C
Sbjct: 979 HPC 981
Score = 70.9 bits (172), Expect = 3e-11
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C
Sbjct: 434 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 493
Query: 3163 NCSCVSGLIANCSSWPCA 3180
C+C SG W C+
Sbjct: 494 TCTCTSG------KWECS 505
Score = 70.9 bits (172), Expect = 3e-11
Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867
C + S C C C L C ++ C GC CP L CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925
P C C Q + PPG + C C G SC P
Sbjct: 839 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 885
Query: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
G+ + + +L L + E + SGC C G R +PE+
Sbjct: 886 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 944
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
C C G+ + PG + C +C+C G CT H TC
Sbjct: 945 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 985
Score = 70.1 bits (170), Expect = 5e-11
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)
Query: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466
W E P G T S C G E EA + +AC +Y
Sbjct: 313 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 370
Query: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
A+C D + G W C + +RAC+ + GRP G TQ R C +
Sbjct: 371 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 417
Query: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584
C + + + C CP SC P + C + C C CP G + +DG CV PA
Sbjct: 418 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 472
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
C C++ G+ + PG VV C+ CTC +G +C CP
Sbjct: 473 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 510
Score = 70.1 bits (170), Expect = 5e-11
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)
Query: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
C C +G + W A E R C P Q T+ RQ C + C E
Sbjct: 373 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 421
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875
+ C CP C P A CV C GC CP G + +G CV P CPC
Sbjct: 422 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 476
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
H + PPG+V+ +C C C G + CS C
Sbjct: 477 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 70.1 bits (170), Expect = 5e-11
Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)
Query: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167
S G C + C Q + A L E C W G+ ++ G C +C +
Sbjct: 917 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 971
Query: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226
S L P A +TC ++ HYRTFDG + F+G C +L+ +D
Sbjct: 972 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017
Query: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278
+++V + C G R + +G ++ +GN S + L E +W +
Sbjct: 1018 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076
Query: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
+ LV + + D+ ++ + + GQ GLCG ++ ++ P
Sbjct: 1077 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1129
Query: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396
FG+SW AVE DP + +++ EP A+ C
Sbjct: 1130 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1174
Query: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
LL F CH V ++ CL C G Q G + CA+ ++Y C + +
Sbjct: 1175 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1229
Query: 457 IRWRKPGFCERLCP 470
+ WR P RLCP
Sbjct: 1230 VDWRTP----RLCP 1239
Score = 69.7 bits (169), Expect = 7e-11
Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846
C+AP G S C G D E PP + + L P + CS
Sbjct: 788 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 847
Query: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901
G PGD+ P H +D C+++ A CP +F + H +
Sbjct: 848 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 898
Query: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958
R C Q + G C GC CP GL H +C +CPC G+ Y G
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 958
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ C+ C C G CT C C
Sbjct: 959 QV-MSPCHTCVCQRGSFQCTLHPCASTC 985
Score = 68.9 bits (167), Expect = 1e-10
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373
P PC + + C L+ C++ L T C S C ++W
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 387
Query: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433
CR L + A A+AG P R C + +C E + F ++ C
Sbjct: 388 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 430
Query: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491
+ C C S C D C GCYCP GL+ + GGC+ P EC C +H G
Sbjct: 431 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 481
Query: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519
PG ++ C C C G+ C++ C
Sbjct: 482 YPPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 68.9 bits (167), Expect = 1e-10
Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)
Query: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351
LP +C A + EYSPC PC R+C DL C GC CPP
Sbjct: 772 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 829
Query: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
L + +CV CSC G + PG + HC C +G ++C P
Sbjct: 830 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 882
Query: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466
CP + + CS SR R C PC +G A G +AC
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
CP + P SPC C+ CQ
Sbjct: 943 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 972
Query: 3523 STQCTDCGGGQSLHPCGQPC 3542
S QCT LHPC C
Sbjct: 973 SFQCT-------LHPCASTC 985
Score = 66.6 bits (161), Expect = 6e-10
Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)
Query: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
PC +C +H + C R P R + C C + PC PC
Sbjct: 746 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 792
Query: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592
R+CQDL+ C G G C C CP +Q LCVP C C +Q
Sbjct: 793 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 848
Query: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
G+ PG+ +C C G++ C
Sbjct: 849 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 875
Query: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710
+R P A CPAG+++ C
Sbjct: 876 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 898
Query: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764
+C + + G C GC CP+G +H AC +ECPC W
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCT---W------ 949
Query: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+ PGD++ S C C C G C+L C +G
Sbjct: 950 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 989
Score = 66.6 bits (161), Expect = 6e-10
Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)
Query: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533
+S+ EA+ E + CV E C R + G L + HCP R
Sbjct: 2029 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2088
Query: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593
+ G VR + C W CA C++ D ++TFDG + + + Y L
Sbjct: 2089 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2138
Query: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642
Q + + +L+ + + G CL V L TH+ R + V V+ Q
Sbjct: 2139 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702
V P + G + +++L Q+ W S + + Q GLCG
Sbjct: 2195 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2253
Query: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759
+ +D G V A F +QV S+L S T + + A C
Sbjct: 2254 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2304
Query: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812
+ ++ + F CHR V E F ++R V C L+ Y C +
Sbjct: 2305 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2357
Query: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863
WR CP +C Y+ C AC + C PE C LG GC C
Sbjct: 2358 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2414
Query: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917
G + C+P + C C +G R ++++ C + CQ C
Sbjct: 2415 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2474
Query: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964
PS PR L + A LL P C G+ C C PG LL
Sbjct: 2475 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2525
Query: 965 ----DERCVPPDLCPC 976
++ C P C C
Sbjct: 2526 THFQEDSCCPSYSCEC 2541
Score = 64.7 bits (156), Expect = 2e-09
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338
+ L +Y G Q + CT + Y+ C CP SC CV
Sbjct: 389 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 448
Query: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
C GCYCP G + G CV P C C G + PG+ + + CN CTC G+
Sbjct: 449 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 502
Query: 3399 NCTDLPCP 3406
C+ CP
Sbjct: 503 ECSTAVCP 510
Score = 64.3 bits (155), Expect = 3e-09
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)
Query: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105
C+ A CPAG V C++ R C + C GC CP+G L
Sbjct: 874 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 933
Query: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
C C CT +G + PG Q C+ C CQ G CT PC
Sbjct: 934 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 981
Score = 63.9 bits (154), Expect = 4e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)
Query: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639
VD PP G + P G+ C C G+V+V+ L +C
Sbjct: 850 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 907
Query: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697
N S S G C+ GC CP GLL H C ECPC + +PG ++ C
Sbjct: 908 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 966
Query: 2698 CVCEKGELLCQPGGCPLPC 2716
CVC++G C C C
Sbjct: 967 CVCQRGSFQCTLHPCASTC 985
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)
Query: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756
P PC + QG +C L C + S FTA+C D G+ +TW
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 387
Query: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813
CR R C P G RT Q + C A
Sbjct: 388 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 426
Query: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
E + A CP +C + +C GC+CP G + +G CV P +CPC
Sbjct: 427 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 478
Query: 1874 GARYWPGQRIKADCQLCICQDGR 1896
G Y PG +K DC C C G+
Sbjct: 479 GTLYPPGSVVKEDCNTCTCTSGK 501
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S +
Sbjct: 433 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 488
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G+ C CP C
Sbjct: 489 KEDCNTCTCTSGKWECSTAVCPAEC 513
Score = 62.0 bits (149), Expect = 1e-08
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125
G+ C P CP + +++C+ ELS R Q C GC C
Sbjct: 870 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 928
Query: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA
Sbjct: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 982
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513
PC GC CP+GLL C PEEC C G PGD++ C C C+RG
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 975
Query: 4514 CTSQGC 4519
CT C
Sbjct: 976 CTLHPC 981
Score = 60.5 bits (145), Expect = 4e-08
Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)
Query: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751
C A +SP PC RTC + C G G + C ACP D
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 828
Query: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
T + V C CH G +L G H C
Sbjct: 829 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 878
Query: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859
P A C +F C+ TC+ ++ PC S GC CP+G + +
Sbjct: 879 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 937
Query: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C
Sbjct: 938 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 985
Score = 58.2 bits (139), Expect = 2e-07
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091
CA H A LC + +P C C A E C C R C DL C D
Sbjct: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808
Query: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142
C +GC CP + Q CVP C C QG + PG + +C C
Sbjct: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 867
Query: 4143 QAGQLSC----TAQPCP 4155
+ G +SC A CP
Sbjct: 868 KDGVMSCDSRAPAAACP 884
Score = 53.9 bits (128), Expect = 4e-06
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)
Query: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734
+C CP SC R C+ C GC CP G + +DG CV + C C
Sbjct: 428 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 480
Query: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
P V+ DC CTC + C CP
Sbjct: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 510
Score = 51.2 bits (121), Expect = 3e-05
Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)
Query: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863
CP C AC T+C P C Q G + +P CQ GC C G +LH +
Sbjct: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424
Query: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
C+P C CT +P W +L+ Q Q P T++
Sbjct: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2469
Query: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970
VD P + GE+ L T CL Q+ C + C+PGH
Sbjct: 2470 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2524
Query: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029
Q C P CEC P L CE+ L P C Q +T G+
Sbjct: 2525 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2568
Query: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083
C C PE Q + LT RN T+ C L Q C + C
Sbjct: 2569 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2623
Query: 5084 STHVM----PEE--PYLQSQCDC 5100
T ++ P+ PY +CDC
Sbjct: 2624 GTALVEVWSPDRCCPYKSCECDC 2646
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
+R CA+ P G Q R C+ C+E Y EC CP SC H
Sbjct: 395 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 446
Query: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784
C +GC+CP G CV ECPC E T+ PG
Sbjct: 447 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 486
Query: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807
++ C C+C GK CS C
Sbjct: 487 VVKEDCNTCTCTSGKWECSTAVC 509
Score = 49.3 bits (116), Expect = 1e-04
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137
C K++ C A +C +L++P + C GC CP L ++CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P C C +G YPPG + + +C C G+++ S P A
Sbjct: 839 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 881
Score = 48.9 bits (115), Expect = 1e-04
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472
SC E+ C +PC C S + C DL C GC CP L QA C
Sbjct: 778 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527
+P +C+C G+ PGD C C+ G + C S+ P +
Sbjct: 838 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 887
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
W S+CS G ++ PC Q ++Q C G++ + C+
Sbjct: 680 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 724
Query: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888
+ + Q C ++ C+ G C L H A C +H LP L
Sbjct: 725 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 772
Query: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947
P L+ ++ C P G T Q +A E C ++
Sbjct: 773 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 809
Query: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006
++ C GC C P + +QA CVP + C C G + PG + C
Sbjct: 810 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065
C G C C G+ V C + + +C Q L L +G
Sbjct: 866 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 920
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
C +S C+ CP + +L +C C
Sbjct: 921 PC------LSGCA--CPQGLLRHGDACFLPEECPC 947
Score = 46.6 bits (109), Expect = 6e-04
Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)
Query: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269
CA P T A L +P CS C QG D G HC C
Sbjct: 822 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 868
Query: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325
G+ S CD P A CP NC+ +
Sbjct: 869 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 906
Query: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384
C + +L V C GC CP G L +G C P C C G+ + PG ++
Sbjct: 907 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 962
Query: 3385 PDGCNHCTCLEGRLNCTDLPC 3405
P C+ C C G CT PC
Sbjct: 963 P--CHTCVCQRGSFQCTLHPC 981
Score = 45.4 bits (106), Expect = 0.001
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108
C C + C C P+ C Q+GI+ D QV +GC C +G++
Sbjct: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424
Query: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159
C+P C CTD+ G A G + + C CQA L C P P P
Sbjct: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2481
Query: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211
C + + P C G + AP CR + CP SC
Sbjct: 2482 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2540
Query: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254
P LC + S + G CT C D ++PE
Sbjct: 2541 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2586
Score = 44.7 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018
A GC C P + G CV C C G + PGS +E C +C C SG+ C+
Sbjct: 449 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507
Query: 5019 CSPLTCA 5025
P C+
Sbjct: 508 VCPAECS 514
Score = 43.1 bits (100), Expect = 0.007
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679
V PC +C D + +C CVEGC CPP L DT+ C+P ++C C
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 847
Query: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707
+ + +P + + C C+ G + C
Sbjct: 848 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 874
Score = 35.4 bits (80), Expect = 1.5
Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)
Query: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898
+T +PC + R S C P ++ C T+ QPC A + C
Sbjct: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2359
Query: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
+ CP LC + C C P TC G+ P CQ+ G+
Sbjct: 2360 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2413
Query: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012
L ++ C+ K ACT S P A G W+ +L C C
Sbjct: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2465
Query: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059
T P G C P E+ E L P P G C + C G
Sbjct: 2466 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2521
Query: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117
+R T S +C P C + C +D+ + G + C G
Sbjct: 2522 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2581
Query: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174
P C + + N +C P C C P C + L+
Sbjct: 2582 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2628
Query: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205
WSP P+ C C RCH
Sbjct: 2629 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2655
Score = 34.7 bits (78), Expect = 2.5
Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)
Query: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677
CQ G++ P LDP+ HC EGC C G +L H C+P ++C C
Sbjct: 2391 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2438
Query: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715
+GE W + L C Q C+ + + GCP P
Sbjct: 2439 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477
Score = 34.3 bits (77), Expect = 3.3
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLP---PCQPGCYCPKGLLEQAGGCIPPEEC---NC 4480
+ + AC SPC C + C+D+P C P C P+ L E C+ E+C
Sbjct: 1410 WRYDACASPCFQTCRDPRAAS-CRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1468
Query: 4481 WHTSAAGAGMTLAPGDRL 4498
W + A TL P L
Sbjct: 1469 WVPTEALGNETLPPSQGL 1486
Score = 32.7 bits (73), Expect = 9.6
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344
++L S +P QLL GL P + ++P T PGP + V
Sbjct: 1799 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1840
Query: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402
TTP+ Q +A TLP + PV P TPA + A P G P +LG
Sbjct: 1841 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1890
Score = 32.7 bits (73), Expect = 9.6
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
Query: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582
C + C C P++CQD G + CQ GC + G L + LC+P
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2430
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFS 3609
A C C +MG+P + S S
Sbjct: 2431 AKCAC---TDSMGVPRALGETWNSSLS 2454
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 546 bits (1408), Expect = e-154
Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249
C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
Query: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
+G +E+ + A V+ G V ++ LQ L ++++ + D +
Sbjct: 139 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364
+ I + EL G T GLCG N P+DD + G L F +SW+ P G +
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
C PG ++ + C LL PF CHA VSP + +C C
Sbjct: 256 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 307
Query: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481
G C A Y +ACA+ ++ WR C C Y++C++
Sbjct: 308 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CP SC SC + CV GC CP GL + CV A CPC + Y PG
Sbjct: 361 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 415
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L +
Sbjct: 416 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 473
Query: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652
G + L++ C G+C+ ++SV L + L +G VL+ Q +P +
Sbjct: 474 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 533
Query: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711
+RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P
Sbjct: 534 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 593
Query: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771
G E++ F + ++ P + L PC H Q +++ AC++L +F C
Sbjct: 594 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 652
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830
+ P++ +C C C G CLC L+ YA C + G +R + C + C
Sbjct: 653 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 710
Query: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879
+EY C CG+ C PE CG G CV GC CP D + CVP +
Sbjct: 711 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 770
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935
C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L
Sbjct: 771 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 827
Query: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988
TC+ N S A GC CP G + + C P+ CPC G+ Y P
Sbjct: 828 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047
+ C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S +
Sbjct: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 947
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106
F+V +N+ C +SG+ C K +++ + +++ V + P+ + +
Sbjct: 948 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1000
Query: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + +
Sbjct: 1001 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1060
Query: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224
+ SW + CP+ D C +N R +A+ C LL +F +CH V
Sbjct: 1061 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1119
Query: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+
Sbjct: 1120 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
Score = 255 bits (651), Expect = 9e-67
Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
L CT HC +AF E + C +C ++ DGC CP G + D C
Sbjct: 340 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
Query: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG
Sbjct: 396 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 455
Query: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082
+T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G
Sbjct: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 515
Query: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140
+ + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++
Sbjct: 516 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198
GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 633
Query: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
++ C L +F C A + P ++E C DAC C CLC+ +A YA C R
Sbjct: 634 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 689
Query: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311
HG V +R++ C+L CE + Y C C TC + PE G CVEG
Sbjct: 690 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 749
Query: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C CP T L A C+ C C + +PPG G+C C++G C
Sbjct: 750 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 802
Score = 214 bits (546), Expect = 1e-54
Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
+C P L C + G+ P N R + + G R C+A G H TFD
Sbjct: 32 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 91
Query: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081
GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+
Sbjct: 92 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 149
Query: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141
+ VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G
Sbjct: 150 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 207
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195
GLCG+ + D +DL + G L HSW+ P P LP P + N
Sbjct: 208 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 267
Query: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
+C ALL+P F CHA V P C D C S GD C A+A YA
Sbjct: 268 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 325
Query: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312
CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC
Sbjct: 326 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 382
Query: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
+CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C
Sbjct: 383 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 432
Score = 146 bits (369), Expect = 5e-34
Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)
Query: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144
W +R C HC E KA C A C +A ++ ++ C P
Sbjct: 336 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 386
Query: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199
G + DG A C + + PGS G+ A C+
Sbjct: 387 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 445
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250
H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++
Sbjct: 446 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
Query: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305
+ L QAG+V + Q ++P ++ + LS +L + +GV V DR G
Sbjct: 506 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 561
Query: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365
+ + VD T GLCG +NG +DDF+ P G FGNSW+ L A
Sbjct: 562 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 614
Query: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
PL D HL+A + V C L F C A +SP Y E C C
Sbjct: 615 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480
Q +CAT A Y C RRH + R R P C C + YS CV+
Sbjct: 670 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 718
Query: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531
C +C EA G G ++ R+ECV GC CP + + LCVP C C++
Sbjct: 719 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 778
Query: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567
Y PGD+ C C+DG C A C G
Sbjct: 779 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 814
Score = 98.2 bits (243), Expect = 2e-19
Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)
Query: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061
W C + RC +VTFDG Y+L + + TV + G
Sbjct: 2033 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2087
Query: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116
L V L T + H + R VTV+ V PP + G + G ++ T
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2145
Query: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172
+ + W ++V+ S + + GLCG DGDA+NDL + G + AE A
Sbjct: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205
Query: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225
SW++ G P C A C L+ + F+ CH VPP+
Sbjct: 2206 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2256
Query: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
E + D C A+ Y C + + WR + C C Y+AC
Sbjct: 2257 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2310
Query: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333
C P TC + P HCQV+ EGC C EGT+L H C+ A C C
Sbjct: 2311 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2368
Query: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357
W P +++ D G +C C
Sbjct: 2369 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
Query: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C + CE L P C G L QE+ C + CD D C E P
Sbjct: 2429 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2480
Query: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465
C + Q +T G + C CGD CP + C +G L
Sbjct: 2481 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2521
Score = 85.1 bits (209), Expect = 2e-15
Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913
C +LA C + TQ CT C E + C CP C +
Sbjct: 316 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 369
Query: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973
++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG
Sbjct: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 428
Query: 2974 KMACTSERCPVAC 2986
K C++ CP C
Sbjct: 429 KWECSTAVCPAEC 441
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)
Query: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207
Q R S+H P A+ P + LA VG LW R C+ + + TFD
Sbjct: 1996 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2051
Query: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258
G H Y+L+ + D VH+ + GH +T +V I
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2110
Query: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317
N V L P +G ++ G +++L+ + L +G + +
Sbjct: 2111 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170
Query: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374
Q GLCG+ +G +D G G A A F +SW++P S + C
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2227
Query: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433
D P C +++ F CH V P + E +
Sbjct: 2228 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2264
Query: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489
Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ +
Sbjct: 2265 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
Query: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526
G + E C + GC C G + LC+P A C C
Sbjct: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 73.9 bits (180), Expect = 4e-12
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087
+R+C+ G P G R Q R C + C+ E + C CP C
Sbjct: 323 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 370
Query: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146
C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+
Sbjct: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 429
Query: 4147 LSCTAQPCP 4155
C+ CP
Sbjct: 430 WECSTAVCP 438
Score = 72.4 bits (176), Expect = 1e-11
Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)
Query: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576
+ W S C P + S L P A+ +++ + +P L+P+ EQ R
Sbjct: 606 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 665
Query: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626
C G P LC LC G AC SC+ S +SP
Sbjct: 666 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 715
Query: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684
C PC G C++ + E+C +GG
Sbjct: 716 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 738
Query: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742
D R +C++G C CPP + Q CVP + C C + P +
Sbjct: 739 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 786
Query: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+C C + + C P CP + +CS + R RTCE
Sbjct: 787 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 836
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858
+Q NL ++ + PC GC CP G
Sbjct: 837 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 859
Query: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918
L H C P CPCT W + +E PG + C CVC G+F C+L
Sbjct: 860 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 906
Query: 4919 VDC 4921
C
Sbjct: 907 HPC 909
Score = 70.9 bits (172), Expect = 3e-11
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C
Sbjct: 362 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 421
Query: 3163 NCSCVSGLIANCSSWPCA 3180
C+C SG W C+
Sbjct: 422 TCTCTSG------KWECS 433
Score = 70.9 bits (172), Expect = 3e-11
Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867
C + S C C C L C ++ C GC CP L CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925
P C C Q + PPG + C C G SC P
Sbjct: 767 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 813
Query: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
G+ + + +L L + E + SGC C G R +PE+
Sbjct: 814 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 872
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
C C G+ + PG + C +C+C G CT H TC
Sbjct: 873 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 913
Score = 70.1 bits (170), Expect = 5e-11
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)
Query: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466
W E P G T S C G E EA + +AC +Y
Sbjct: 241 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 298
Query: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
A+C D + G W C + +RAC+ + GRP G TQ R C +
Sbjct: 299 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 345
Query: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584
C + + + C CP SC P + C + C C CP G + +DG CV PA
Sbjct: 346 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 400
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
C C++ G+ + PG VV C+ CTC +G +C CP
Sbjct: 401 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 438
Score = 70.1 bits (170), Expect = 5e-11
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)
Query: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
C C +G + W A E R C P Q T+ RQ C + C E
Sbjct: 301 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 349
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875
+ C CP C P A CV C GC CP G + +G CV P CPC
Sbjct: 350 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 404
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
H + PPG+V+ +C C C G + CS C
Sbjct: 405 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 70.1 bits (170), Expect = 5e-11
Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)
Query: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167
S G C + C Q + A L E C W G+ ++ G C +C +
Sbjct: 845 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 899
Query: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226
S L P A +TC ++ HYRTFDG + F+G C +L+ +D
Sbjct: 900 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
Query: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278
+++V + C G R + +G ++ +GN S + L E +W +
Sbjct: 946 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
Query: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
+ LV + + D+ ++ + + GQ GLCG ++ ++ P
Sbjct: 1005 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1057
Query: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396
FG+SW AVE DP + +++ EP A+ C
Sbjct: 1058 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1102
Query: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
LL F CH V ++ CL C G Q G + CA+ ++Y C + +
Sbjct: 1103 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1157
Query: 457 IRWRKPGFCERLCP 470
+ WR P RLCP
Sbjct: 1158 VDWRTP----RLCP 1167
Score = 69.7 bits (169), Expect = 7e-11
Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846
C+AP G S C G D E PP + + L P + CS
Sbjct: 716 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 775
Query: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901
G PGD+ P H +D C+++ A CP +F + H +
Sbjct: 776 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 826
Query: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958
R C Q + G C GC CP GL H +C +CPC G+ Y G
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 886
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ C+ C C G CT C C
Sbjct: 887 QV-MSPCHTCVCQRGSFQCTLHPCASTC 913
Score = 68.9 bits (167), Expect = 1e-10
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373
P PC + + C L+ C++ L T C S C ++W
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 315
Query: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433
CR L + A A+AG P R C + +C E + F ++ C
Sbjct: 316 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 358
Query: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491
+ C C S C D C GCYCP GL+ + GGC+ P EC C +H G
Sbjct: 359 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 409
Query: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519
PG ++ C C C G+ C++ C
Sbjct: 410 YPPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 68.9 bits (167), Expect = 1e-10
Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)
Query: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351
LP +C A + EYSPC PC R+C DL C GC CPP
Sbjct: 700 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 757
Query: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
L + +CV CSC G + PG + HC C +G ++C P
Sbjct: 758 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 810
Query: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466
CP + + CS SR R C PC +G A G +AC
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
CP + P SPC C+ CQ
Sbjct: 871 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 900
Query: 3523 STQCTDCGGGQSLHPCGQPC 3542
S QCT LHPC C
Sbjct: 901 SFQCT-------LHPCASTC 913
Score = 66.6 bits (161), Expect = 6e-10
Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)
Query: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
PC +C +H + C R P R + C C + PC PC
Sbjct: 674 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 720
Query: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592
R+CQDL+ C G G C C CP +Q LCVP C C +Q
Sbjct: 721 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 776
Query: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
G+ PG+ +C C G++ C
Sbjct: 777 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 803
Query: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710
+R P A CPAG+++ C
Sbjct: 804 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 826
Query: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764
+C + + G C GC CP+G +H AC +ECPC W
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCT---W------ 877
Query: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+ PGD++ S C C C G C+L C +G
Sbjct: 878 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 917
Score = 66.6 bits (161), Expect = 6e-10
Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)
Query: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533
+S+ EA+ E + CV E C R + G L + HCP R
Sbjct: 1957 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2016
Query: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593
+ G VR + C W CA C++ D ++TFDG + + + Y L
Sbjct: 2017 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2066
Query: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642
Q + + +L+ + + G CL V L TH+ R + V V+ Q
Sbjct: 2067 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702
V P + G + +++L Q+ W S + + Q GLCG
Sbjct: 2123 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2181
Query: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759
+ +D G V A F +QV S+L S T + + A C
Sbjct: 2182 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2232
Query: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812
+ ++ + F CHR V E F ++R V C L+ Y C +
Sbjct: 2233 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2285
Query: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863
WR CP +C Y+ C AC + C PE C LG GC C
Sbjct: 2286 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2342
Query: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917
G + C+P + C C +G R ++++ C + CQ C
Sbjct: 2343 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2402
Query: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964
PS PR L + A LL P C G+ C C PG LL
Sbjct: 2403 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2453
Query: 965 ----DERCVPPDLCPC 976
++ C P C C
Sbjct: 2454 THFQEDSCCPSYSCEC 2469
Score = 64.7 bits (156), Expect = 2e-09
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338
+ L +Y G Q + CT + Y+ C CP SC CV
Sbjct: 317 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 376
Query: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
C GCYCP G + G CV P C C G + PG+ + + CN CTC G+
Sbjct: 377 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 430
Query: 3399 NCTDLPCP 3406
C+ CP
Sbjct: 431 ECSTAVCP 438
Score = 64.3 bits (155), Expect = 3e-09
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)
Query: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105
C+ A CPAG V C++ R C + C GC CP+G L
Sbjct: 802 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 861
Query: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
C C CT +G + PG Q C+ C CQ G CT PC
Sbjct: 862 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
Score = 63.9 bits (154), Expect = 4e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)
Query: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639
VD PP G + P G+ C C G+V+V+ L +C
Sbjct: 778 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 835
Query: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697
N S S G C+ GC CP GLL H C ECPC + +PG ++ C
Sbjct: 836 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 894
Query: 2698 CVCEKGELLCQPGGCPLPC 2716
CVC++G C C C
Sbjct: 895 CVCQRGSFQCTLHPCASTC 913
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)
Query: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756
P PC + QG +C L C + S FTA+C D G+ +TW
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 315
Query: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813
CR R C P G RT Q + C A
Sbjct: 316 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 354
Query: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
E + A CP +C + +C GC+CP G + +G CV P +CPC
Sbjct: 355 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 406
Query: 1874 GARYWPGQRIKADCQLCICQDGR 1896
G Y PG +K DC C C G+
Sbjct: 407 GTLYPPGSVVKEDCNTCTCTSGK 429
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S +
Sbjct: 361 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 416
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G+ C CP C
Sbjct: 417 KEDCNTCTCTSGKWECSTAVCPAEC 441
Score = 62.0 bits (149), Expect = 1e-08
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125
G+ C P CP + +++C+ ELS R Q C GC C
Sbjct: 798 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 856
Query: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA
Sbjct: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 910
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513
PC GC CP+GLL C PEEC C G PGD++ C C C+RG
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 903
Query: 4514 CTSQGC 4519
CT C
Sbjct: 904 CTLHPC 909
Score = 60.5 bits (145), Expect = 4e-08
Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)
Query: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751
C A +SP PC RTC + C G G + C ACP D
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 756
Query: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
T + V C CH G +L G H C
Sbjct: 757 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 806
Query: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859
P A C +F C+ TC+ ++ PC S GC CP+G + +
Sbjct: 807 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 865
Query: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C
Sbjct: 866 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 913
Score = 58.2 bits (139), Expect = 2e-07
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091
CA H A LC + +P C C A E C C R C DL C D
Sbjct: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
Query: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142
C +GC CP + Q CVP C C QG + PG + +C C
Sbjct: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 795
Query: 4143 QAGQLSC----TAQPCP 4155
+ G +SC A CP
Sbjct: 796 KDGVMSCDSRAPAAACP 812
Score = 53.9 bits (128), Expect = 4e-06
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)
Query: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734
+C CP SC R C+ C GC CP G + +DG CV + C C
Sbjct: 356 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 408
Query: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
P V+ DC CTC + C CP
Sbjct: 409 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 438
Score = 51.2 bits (121), Expect = 3e-05
Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)
Query: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863
CP C AC T+C P C Q G + +P CQ GC C G +LH +
Sbjct: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
Query: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
C+P C CT +P W +L+ Q Q P T++
Sbjct: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2397
Query: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970
VD P + GE+ L T CL Q+ C + C+PGH
Sbjct: 2398 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2452
Query: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029
Q C P CEC P L CE+ L P C Q +T G+
Sbjct: 2453 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2496
Query: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083
C C PE Q + LT RN T+ C L Q C + C
Sbjct: 2497 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2551
Query: 5084 STHVM----PEE--PYLQSQCDC 5100
T ++ P+ PY +CDC
Sbjct: 2552 GTALVEVWSPDRCCPYKSCECDC 2574
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
+R CA+ P G Q R C+ C+E Y EC CP SC H
Sbjct: 323 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 374
Query: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784
C +GC+CP G CV ECPC E T+ PG
Sbjct: 375 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 414
Query: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807
++ C C+C GK CS C
Sbjct: 415 VVKEDCNTCTCTSGKWECSTAVC 437
Score = 49.3 bits (116), Expect = 1e-04
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137
C K++ C A +C +L++P + C GC CP L ++CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P C C +G YPPG + + +C C G+++ S P A
Sbjct: 767 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 809
Score = 48.9 bits (115), Expect = 1e-04
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472
SC E+ C +PC C S + C DL C GC CP L QA C
Sbjct: 706 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527
+P +C+C G+ PGD C C+ G + C S+ P +
Sbjct: 766 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 815
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
W S+CS G ++ PC Q ++Q C G++ + C+
Sbjct: 608 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 652
Query: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888
+ + Q C ++ C+ G C L H A C +H LP L
Sbjct: 653 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 700
Query: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947
P L+ ++ C P G T Q +A E C ++
Sbjct: 701 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 737
Query: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006
++ C GC C P + +QA CVP + C C G + PG + C
Sbjct: 738 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065
C G C C G+ V C + + +C Q L L +G
Sbjct: 794 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 848
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
C +S C+ CP + +L +C C
Sbjct: 849 PC------LSGCA--CPQGLLRHGDACFLPEECPC 875
Score = 46.6 bits (109), Expect = 6e-04
Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)
Query: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269
CA P T A L +P CS C QG D G HC C
Sbjct: 750 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 796
Query: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325
G+ S CD P A CP NC+ +
Sbjct: 797 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 834
Query: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384
C + +L V C GC CP G L +G C P C C G+ + PG ++
Sbjct: 835 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 890
Query: 3385 PDGCNHCTCLEGRLNCTDLPC 3405
P C+ C C G CT PC
Sbjct: 891 P--CHTCVCQRGSFQCTLHPC 909
Score = 45.4 bits (106), Expect = 0.001
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108
C C + C C P+ C Q+GI+ D QV +GC C +G++
Sbjct: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
Query: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159
C+P C CTD+ G A G + + C CQA L C P P P
Sbjct: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2409
Query: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211
C + + P C G + AP CR + CP SC
Sbjct: 2410 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2468
Query: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254
P LC + S + G CT C D ++PE
Sbjct: 2469 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2514
Score = 44.7 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018
A GC C P + G CV C C G + PGS +E C +C C SG+ C+
Sbjct: 377 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
Query: 5019 CSPLTCA 5025
P C+
Sbjct: 436 VCPAECS 442
Score = 43.1 bits (100), Expect = 0.007
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679
V PC +C D + +C CVEGC CPP L DT+ C+P ++C C
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 775
Query: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707
+ + +P + + C C+ G + C
Sbjct: 776 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 802
Score = 35.4 bits (80), Expect = 1.5
Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)
Query: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898
+T +PC + R S C P ++ C T+ QPC A + C
Sbjct: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2287
Query: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
+ CP LC + C C P TC G+ P CQ+ G+
Sbjct: 2288 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2341
Query: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012
L ++ C+ K ACT S P A G W+ +L C C
Sbjct: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2393
Query: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059
T P G C P E+ E L P P G C + C G
Sbjct: 2394 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2449
Query: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117
+R T S +C P C + C +D+ + G + C G
Sbjct: 2450 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2509
Query: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174
P C + + N +C P C C P C + L+
Sbjct: 2510 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2556
Query: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205
WSP P+ C C RCH
Sbjct: 2557 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2583
Score = 34.7 bits (78), Expect = 2.5
Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)
Query: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677
CQ G++ P LDP+ HC EGC C G +L H C+P ++C C
Sbjct: 2319 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2366
Query: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715
+GE W + L C Q C+ + + GCP P
Sbjct: 2367 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
Score = 33.9 bits (76), Expect = 4.3
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPP---CQPGCYCPKGLLEQAGGCIPPEEC---NC 4480
+ + AC SPC C + C+D+P C P C P+ L E C+ E+C
Sbjct: 1338 WRYDACASPCFQTCRDPRAAS-CRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1396
Query: 4481 WHTSAAGAGMTLAPGDRL 4498
W + A TL P L
Sbjct: 1397 WVPTEALGNETLPPSQGL 1414
Score = 32.7 bits (73), Expect = 9.6
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344
++L S +P QLL GL P + ++P T PGP + V
Sbjct: 1727 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1768
Query: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402
TTP+ Q +A TLP + PV P TPA + A P G P +LG
Sbjct: 1769 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
Score = 32.7 bits (73), Expect = 9.6
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
Query: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582
C + C C P++CQD G + CQ GC + G L + LC+P
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2358
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFS 3609
A C C +MG+P + S S
Sbjct: 2359 AKCAC---TDSMGVPRALGETWNSSLS 2382
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 546 bits (1408), Expect = e-154
Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249
C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210
Query: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
+G +E+ + A V+ G V ++ LQ L ++++ + D +
Sbjct: 211 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364
+ I + EL G T GLCG N P+DD + G L F +SW+ P G +
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
C PG ++ + C LL PF CHA VSP + +C C
Sbjct: 328 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 379
Query: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481
G C A Y +ACA+ ++ WR C C Y++C++
Sbjct: 380 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CP SC SC + CV GC CP GL + CV A CPC + Y PG
Sbjct: 433 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 487
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L +
Sbjct: 488 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 545
Query: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652
G + L++ C G+C+ ++SV L + L +G VL+ Q +P +
Sbjct: 546 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 605
Query: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711
+RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P
Sbjct: 606 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 665
Query: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771
G E++ F + ++ P + L PC H Q +++ AC++L +F C
Sbjct: 666 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 724
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830
+ P++ +C C C G CLC L+ YA C + G +R + C + C
Sbjct: 725 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 782
Query: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879
+EY C CG+ C PE CG G CV GC CP D + CVP +
Sbjct: 783 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 842
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935
C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L
Sbjct: 843 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 899
Query: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988
TC+ N S A GC CP G + + C P+ CPC G+ Y P
Sbjct: 900 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047
+ C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S +
Sbjct: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 1019
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106
F+V +N+ C +SG+ C K +++ + +++ V + P+ + +
Sbjct: 1020 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1072
Query: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + +
Sbjct: 1073 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1132
Query: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224
+ SW + CP+ D C +N R +A+ C LL +F +CH V
Sbjct: 1133 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1191
Query: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+
Sbjct: 1192 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243
Score = 255 bits (651), Expect = 9e-67
Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
L CT HC +AF E + C +C ++ DGC CP G + D C
Sbjct: 412 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 467
Query: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG
Sbjct: 468 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 527
Query: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082
+T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G
Sbjct: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 587
Query: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140
+ + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++
Sbjct: 588 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198
GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 705
Query: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
++ C L +F C A + P ++E C DAC C CLC+ +A YA C R
Sbjct: 706 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 761
Query: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311
HG V +R++ C+L CE + Y C C TC + PE G CVEG
Sbjct: 762 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 821
Query: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C CP T L A C+ C C + +PPG G+C C++G C
Sbjct: 822 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 874
Score = 214 bits (546), Expect = 1e-54
Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
+C P L C + G+ P N R + + G R C+A G H TFD
Sbjct: 104 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 163
Query: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081
GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+
Sbjct: 164 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 221
Query: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141
+ VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G
Sbjct: 222 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 279
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195
GLCG+ + D +DL + G L HSW+ P P LP P + N
Sbjct: 280 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 339
Query: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
+C ALL+P F CHA V P C D C S GD C A+A YA
Sbjct: 340 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 397
Query: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312
CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC
Sbjct: 398 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 454
Query: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
+CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C
Sbjct: 455 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 504
Score = 146 bits (369), Expect = 5e-34
Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)
Query: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144
W +R C HC E KA C A C +A ++ ++ C P
Sbjct: 408 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 458
Query: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199
G + DG A C + + PGS G+ A C+
Sbjct: 459 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 517
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250
H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++
Sbjct: 518 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 577
Query: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305
+ L QAG+V + Q ++P ++ + LS +L + +GV V DR G
Sbjct: 578 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 633
Query: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365
+ + VD T GLCG +NG +DDF+ P G FGNSW+ L A
Sbjct: 634 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 686
Query: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
PL D HL+A + V C L F C A +SP Y E C C
Sbjct: 687 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480
Q +CAT A Y C RRH + R R P C C + YS CV+
Sbjct: 742 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 790
Query: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531
C +C EA G G ++ R+ECV GC CP + + LCVP C C++
Sbjct: 791 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 850
Query: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567
Y PGD+ C C+DG C A C G
Sbjct: 851 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 886
Score = 98.2 bits (243), Expect = 2e-19
Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)
Query: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061
W C + RC +VTFDG Y+L + + TV + G
Sbjct: 2105 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2159
Query: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116
L V L T + H + R VTV+ V PP + G + G ++ T
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2217
Query: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172
+ + W ++V+ S + + GLCG DGDA+NDL + G + AE A
Sbjct: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277
Query: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225
SW++ G P C A C L+ + F+ CH VPP+
Sbjct: 2278 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2328
Query: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
E + D C A+ Y C + + WR + C C Y+AC
Sbjct: 2329 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2382
Query: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333
C P TC + P HCQV+ EGC C EGT+L H C+ A C C
Sbjct: 2383 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2440
Query: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357
W P +++ D G +C C
Sbjct: 2441 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
Query: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C + CE L P C G L QE+ C + CD D C E P
Sbjct: 2501 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2552
Query: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465
C + Q +T G + C CGD CP + C +G L
Sbjct: 2553 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2593
Score = 85.1 bits (209), Expect = 2e-15
Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913
C +LA C + TQ CT C E + C CP C +
Sbjct: 388 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 441
Query: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973
++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG
Sbjct: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 500
Query: 2974 KMACTSERCPVAC 2986
K C++ CP C
Sbjct: 501 KWECSTAVCPAEC 513
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)
Query: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207
Q R S+H P A+ P + LA VG LW R C+ + + TFD
Sbjct: 2068 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2123
Query: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258
G H Y+L+ + D VH+ + GH +T +V I
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2182
Query: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317
N V L P +G ++ G +++L+ + L +G + +
Sbjct: 2183 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2242
Query: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374
Q GLCG+ +G +D G G A A F +SW++P S + C
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2299
Query: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433
D P C +++ F CH V P + E +
Sbjct: 2300 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2336
Query: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489
Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ +
Sbjct: 2337 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2396
Query: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526
G + E C + GC C G + LC+P A C C
Sbjct: 2397 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 73.9 bits (180), Expect = 4e-12
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087
+R+C+ G P G R Q R C + C+ E + C CP C
Sbjct: 395 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 442
Query: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146
C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+
Sbjct: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 501
Query: 4147 LSCTAQPCP 4155
C+ CP
Sbjct: 502 WECSTAVCP 510
Score = 72.4 bits (176), Expect = 1e-11
Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)
Query: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576
+ W S C P + S L P A+ +++ + +P L+P+ EQ R
Sbjct: 678 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 737
Query: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626
C G P LC LC G AC SC+ S +SP
Sbjct: 738 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 787
Query: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684
C PC G C++ + E+C +GG
Sbjct: 788 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 810
Query: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742
D R +C++G C CPP + Q CVP + C C + P +
Sbjct: 811 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 858
Query: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+C C + + C P CP + +CS + R RTCE
Sbjct: 859 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 908
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858
+Q NL ++ + PC GC CP G
Sbjct: 909 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 931
Query: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918
L H C P CPCT W + +E PG + C CVC G+F C+L
Sbjct: 932 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 978
Query: 4919 VDC 4921
C
Sbjct: 979 HPC 981
Score = 70.9 bits (172), Expect = 3e-11
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C
Sbjct: 434 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 493
Query: 3163 NCSCVSGLIANCSSWPCA 3180
C+C SG W C+
Sbjct: 494 TCTCTSG------KWECS 505
Score = 70.9 bits (172), Expect = 3e-11
Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867
C + S C C C L C ++ C GC CP L CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925
P C C Q + PPG + C C G SC P
Sbjct: 839 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 885
Query: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
G+ + + +L L + E + SGC C G R +PE+
Sbjct: 886 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 944
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
C C G+ + PG + C +C+C G CT H TC
Sbjct: 945 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 985
Score = 70.1 bits (170), Expect = 5e-11
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)
Query: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466
W E P G T S C G E EA + +AC +Y
Sbjct: 313 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 370
Query: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
A+C D + G W C + +RAC+ + GRP G TQ R C +
Sbjct: 371 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 417
Query: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584
C + + + C CP SC P + C + C C CP G + +DG CV PA
Sbjct: 418 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 472
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
C C++ G+ + PG VV C+ CTC +G +C CP
Sbjct: 473 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 510
Score = 70.1 bits (170), Expect = 5e-11
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)
Query: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
C C +G + W A E R C P Q T+ RQ C + C E
Sbjct: 373 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 421
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875
+ C CP C P A CV C GC CP G + +G CV P CPC
Sbjct: 422 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 476
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
H + PPG+V+ +C C C G + CS C
Sbjct: 477 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 70.1 bits (170), Expect = 5e-11
Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)
Query: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167
S G C + C Q + A L E C W G+ ++ G C +C +
Sbjct: 917 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 971
Query: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226
S L P A +TC ++ HYRTFDG + F+G C +L+ +D
Sbjct: 972 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017
Query: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278
+++V + C G R + +G ++ +GN S + L E +W +
Sbjct: 1018 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076
Query: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
+ LV + + D+ ++ + + GQ GLCG ++ ++ P
Sbjct: 1077 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1129
Query: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396
FG+SW AVE DP + +++ EP A+ C
Sbjct: 1130 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1174
Query: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
LL F CH V ++ CL C G Q G + CA+ ++Y C + +
Sbjct: 1175 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1229
Query: 457 IRWRKPGFCERLCP 470
+ WR P RLCP
Sbjct: 1230 VDWRTP----RLCP 1239
Score = 69.7 bits (169), Expect = 7e-11
Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846
C+AP G S C G D E PP + + L P + CS
Sbjct: 788 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 847
Query: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901
G PGD+ P H +D C+++ A CP +F + H +
Sbjct: 848 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 898
Query: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958
R C Q + G C GC CP GL H +C +CPC G+ Y G
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 958
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ C+ C C G CT C C
Sbjct: 959 QV-MSPCHTCVCQRGSFQCTLHPCASTC 985
Score = 68.9 bits (167), Expect = 1e-10
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373
P PC + + C L+ C++ L T C S C ++W
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 387
Query: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433
CR L + A A+AG P R C + +C E + F ++ C
Sbjct: 388 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 430
Query: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491
+ C C S C D C GCYCP GL+ + GGC+ P EC C +H G
Sbjct: 431 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 481
Query: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519
PG ++ C C C G+ C++ C
Sbjct: 482 YPPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 68.9 bits (167), Expect = 1e-10
Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)
Query: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351
LP +C A + EYSPC PC R+C DL C GC CPP
Sbjct: 772 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 829
Query: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
L + +CV CSC G + PG + HC C +G ++C P
Sbjct: 830 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 882
Query: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466
CP + + CS SR R C PC +G A G +AC
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
CP + P SPC C+ CQ
Sbjct: 943 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 972
Query: 3523 STQCTDCGGGQSLHPCGQPC 3542
S QCT LHPC C
Sbjct: 973 SFQCT-------LHPCASTC 985
Score = 66.6 bits (161), Expect = 6e-10
Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)
Query: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
PC +C +H + C R P R + C C + PC PC
Sbjct: 746 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 792
Query: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592
R+CQDL+ C G G C C CP +Q LCVP C C +Q
Sbjct: 793 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 848
Query: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
G+ PG+ +C C G++ C
Sbjct: 849 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 875
Query: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710
+R P A CPAG+++ C
Sbjct: 876 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 898
Query: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764
+C + + G C GC CP+G +H AC +ECPC W
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCT---W------ 949
Query: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+ PGD++ S C C C G C+L C +G
Sbjct: 950 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 989
Score = 66.6 bits (161), Expect = 6e-10
Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)
Query: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533
+S+ EA+ E + CV E C R + G L + HCP R
Sbjct: 2029 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2088
Query: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593
+ G VR + C W CA C++ D ++TFDG + + + Y L
Sbjct: 2089 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2138
Query: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642
Q + + +L+ + + G CL V L TH+ R + V V+ Q
Sbjct: 2139 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702
V P + G + +++L Q+ W S + + Q GLCG
Sbjct: 2195 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2253
Query: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759
+ +D G V A F +QV S+L S T + + A C
Sbjct: 2254 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2304
Query: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812
+ ++ + F CHR V E F ++R V C L+ Y C +
Sbjct: 2305 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2357
Query: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863
WR CP +C Y+ C AC + C PE C LG GC C
Sbjct: 2358 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2414
Query: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917
G + C+P + C C +G R ++++ C + CQ C
Sbjct: 2415 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2474
Query: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964
PS PR L + A LL P C G+ C C PG LL
Sbjct: 2475 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2525
Query: 965 ----DERCVPPDLCPC 976
++ C P C C
Sbjct: 2526 THFQEDSCCPSYSCEC 2541
Score = 64.7 bits (156), Expect = 2e-09
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338
+ L +Y G Q + CT + Y+ C CP SC CV
Sbjct: 389 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 448
Query: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
C GCYCP G + G CV P C C G + PG+ + + CN CTC G+
Sbjct: 449 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 502
Query: 3399 NCTDLPCP 3406
C+ CP
Sbjct: 503 ECSTAVCP 510
Score = 64.3 bits (155), Expect = 3e-09
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)
Query: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105
C+ A CPAG V C++ R C + C GC CP+G L
Sbjct: 874 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 933
Query: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
C C CT +G + PG Q C+ C CQ G CT PC
Sbjct: 934 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 981
Score = 63.9 bits (154), Expect = 4e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)
Query: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639
VD PP G + P G+ C C G+V+V+ L +C
Sbjct: 850 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 907
Query: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697
N S S G C+ GC CP GLL H C ECPC + +PG ++ C
Sbjct: 908 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 966
Query: 2698 CVCEKGELLCQPGGCPLPC 2716
CVC++G C C C
Sbjct: 967 CVCQRGSFQCTLHPCASTC 985
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)
Query: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756
P PC + QG +C L C + S FTA+C D G+ +TW
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 387
Query: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813
CR R C P G RT Q + C A
Sbjct: 388 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 426
Query: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
E + A CP +C + +C GC+CP G + +G CV P +CPC
Sbjct: 427 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 478
Query: 1874 GARYWPGQRIKADCQLCICQDGR 1896
G Y PG +K DC C C G+
Sbjct: 479 GTLYPPGSVVKEDCNTCTCTSGK 501
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S +
Sbjct: 433 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 488
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G+ C CP C
Sbjct: 489 KEDCNTCTCTSGKWECSTAVCPAEC 513
Score = 62.0 bits (149), Expect = 1e-08
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125
G+ C P CP + +++C+ ELS R Q C GC C
Sbjct: 870 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 928
Query: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA
Sbjct: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 982
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513
PC GC CP+GLL C PEEC C G PGD++ C C C+RG
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 975
Query: 4514 CTSQGC 4519
CT C
Sbjct: 976 CTLHPC 981
Score = 60.5 bits (145), Expect = 4e-08
Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)
Query: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751
C A +SP PC RTC + C G G + C ACP D
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 828
Query: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
T + V C CH G +L G H C
Sbjct: 829 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 878
Query: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859
P A C +F C+ TC+ ++ PC S GC CP+G + +
Sbjct: 879 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 937
Query: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C
Sbjct: 938 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 985
Score = 58.2 bits (139), Expect = 2e-07
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091
CA H A LC + +P C C A E C C R C DL C D
Sbjct: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808
Query: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142
C +GC CP + Q CVP C C QG + PG + +C C
Sbjct: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 867
Query: 4143 QAGQLSC----TAQPCP 4155
+ G +SC A CP
Sbjct: 868 KDGVMSCDSRAPAAACP 884
Score = 53.9 bits (128), Expect = 4e-06
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)
Query: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734
+C CP SC R C+ C GC CP G + +DG CV + C C
Sbjct: 428 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 480
Query: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
P V+ DC CTC + C CP
Sbjct: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 510
Score = 51.2 bits (121), Expect = 3e-05
Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)
Query: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863
CP C AC T+C P C Q G + +P CQ GC C G +LH +
Sbjct: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424
Query: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
C+P C CT +P W +L+ Q Q P T++
Sbjct: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2469
Query: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970
VD P + GE+ L T CL Q+ C + C+PGH
Sbjct: 2470 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2524
Query: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029
Q C P CEC P L CE+ L P C Q +T G+
Sbjct: 2525 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2568
Query: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083
C C PE Q + LT RN T+ C L Q C + C
Sbjct: 2569 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2623
Query: 5084 STHVM----PEE--PYLQSQCDC 5100
T ++ P+ PY +CDC
Sbjct: 2624 GTALVEVWSPDRCCPYKSCECDC 2646
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
+R CA+ P G Q R C+ C+E Y EC CP SC H
Sbjct: 395 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 446
Query: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784
C +GC+CP G CV ECPC E T+ PG
Sbjct: 447 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 486
Query: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807
++ C C+C GK CS C
Sbjct: 487 VVKEDCNTCTCTSGKWECSTAVC 509
Score = 49.3 bits (116), Expect = 1e-04
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137
C K++ C A +C +L++P + C GC CP L ++CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P C C +G YPPG + + +C C G+++ S P A
Sbjct: 839 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 881
Score = 48.9 bits (115), Expect = 1e-04
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472
SC E+ C +PC C S + C DL C GC CP L QA C
Sbjct: 778 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527
+P +C+C G+ PGD C C+ G + C S+ P +
Sbjct: 838 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 887
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
W S+CS G ++ PC Q ++Q C G++ + C+
Sbjct: 680 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 724
Query: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888
+ + Q C ++ C+ G C L H A C +H LP L
Sbjct: 725 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 772
Query: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947
P L+ ++ C P G T Q +A E C ++
Sbjct: 773 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 809
Query: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006
++ C GC C P + +QA CVP + C C G + PG + C
Sbjct: 810 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065
C G C C G+ V C + + +C Q L L +G
Sbjct: 866 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 920
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
C +S C+ CP + +L +C C
Sbjct: 921 PC------LSGCA--CPQGLLRHGDACFLPEECPC 947
Score = 46.6 bits (109), Expect = 6e-04
Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)
Query: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269
CA P T A L +P CS C QG D G HC C
Sbjct: 822 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 868
Query: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325
G+ S CD P A CP NC+ +
Sbjct: 869 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 906
Query: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384
C + +L V C GC CP G L +G C P C C G+ + PG ++
Sbjct: 907 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 962
Query: 3385 PDGCNHCTCLEGRLNCTDLPC 3405
P C+ C C G CT PC
Sbjct: 963 P--CHTCVCQRGSFQCTLHPC 981
Score = 45.4 bits (106), Expect = 0.001
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108
C C + C C P+ C Q+GI+ D QV +GC C +G++
Sbjct: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424
Query: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159
C+P C CTD+ G A G + + C CQA L C P P P
Sbjct: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2481
Query: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211
C + + P C G + AP CR + CP SC
Sbjct: 2482 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2540
Query: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254
P LC + S + G CT C D ++PE
Sbjct: 2541 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2586
Score = 44.7 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018
A GC C P + G CV C C G + PGS +E C +C C SG+ C+
Sbjct: 449 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507
Query: 5019 CSPLTCA 5025
P C+
Sbjct: 508 VCPAECS 514
Score = 43.1 bits (100), Expect = 0.007
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679
V PC +C D + +C CVEGC CPP L DT+ C+P ++C C
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 847
Query: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707
+ + +P + + C C+ G + C
Sbjct: 848 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 874
Score = 35.4 bits (80), Expect = 1.5
Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)
Query: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898
+T +PC + R S C P ++ C T+ QPC A + C
Sbjct: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2359
Query: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
+ CP LC + C C P TC G+ P CQ+ G+
Sbjct: 2360 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2413
Query: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012
L ++ C+ K ACT S P A G W+ +L C C
Sbjct: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2465
Query: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059
T P G C P E+ E L P P G C + C G
Sbjct: 2466 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2521
Query: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117
+R T S +C P C + C +D+ + G + C G
Sbjct: 2522 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2581
Query: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174
P C + + N +C P C C P C + L+
Sbjct: 2582 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2628
Query: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205
WSP P+ C C RCH
Sbjct: 2629 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2655
Score = 34.7 bits (78), Expect = 2.5
Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)
Query: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677
CQ G++ P LDP+ HC EGC C G +L H C+P ++C C
Sbjct: 2391 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2438
Query: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715
+GE W + L C Q C+ + + GCP P
Sbjct: 2439 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477
Score = 34.3 bits (77), Expect = 3.3
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLP---PCQPGCYCPKGLLEQAGGCIPPEEC---NC 4480
+ + AC SPC C + C+D+P C P C P+ L E C+ E+C
Sbjct: 1410 WRYDACASPCFQTCRDPRAAS-CRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1468
Query: 4481 WHTSAAGAGMTLAPGDRL 4498
W + A TL P L
Sbjct: 1469 WVPTEALGNETLPPSQGL 1486
Score = 32.7 bits (73), Expect = 9.6
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344
++L S +P QLL GL P + ++P T PGP + V
Sbjct: 1799 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1840
Query: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402
TTP+ Q +A TLP + PV P TPA + A P G P +LG
Sbjct: 1841 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1890
Score = 32.7 bits (73), Expect = 9.6
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
Query: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582
C + C C P++CQD G + CQ GC + G L + LC+P
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2430
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFS 3609
A C C +MG+P + S S
Sbjct: 2431 AKCAC---TDSMGVPRALGETWNSSLS 2454
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 546 bits (1408), Expect = e-154
Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249
C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
Query: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
+G +E+ + A V+ G V ++ LQ L ++++ + D +
Sbjct: 139 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364
+ I + EL G T GLCG N P+DD + G L F +SW+ P G +
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
C PG ++ + C LL PF CHA VSP + +C C
Sbjct: 256 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 307
Query: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481
G C A Y +ACA+ ++ WR C C Y++C++
Sbjct: 308 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CP SC SC + CV GC CP GL + CV A CPC + Y PG
Sbjct: 361 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 415
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L +
Sbjct: 416 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 473
Query: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652
G + L++ C G+C+ ++SV L + L +G VL+ Q +P +
Sbjct: 474 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 533
Query: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711
+RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P
Sbjct: 534 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 593
Query: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771
G E++ F + ++ P + L PC H Q +++ AC++L +F C
Sbjct: 594 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 652
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830
+ P++ +C C C G CLC L+ YA C + G +R + C + C
Sbjct: 653 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 710
Query: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879
+EY C CG+ C PE CG G CV GC CP D + CVP +
Sbjct: 711 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 770
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935
C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L
Sbjct: 771 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 827
Query: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988
TC+ N S A GC CP G + + C P+ CPC G+ Y P
Sbjct: 828 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047
+ C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S +
Sbjct: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 947
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106
F+V +N+ C +SG+ C K +++ + +++ V + P+ + +
Sbjct: 948 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1000
Query: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + +
Sbjct: 1001 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1060
Query: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224
+ SW + CP+ D C +N R +A+ C LL +F +CH V
Sbjct: 1061 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1119
Query: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+
Sbjct: 1120 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
Score = 255 bits (651), Expect = 9e-67
Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
L CT HC +AF E + C +C ++ DGC CP G + D C
Sbjct: 340 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
Query: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG
Sbjct: 396 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 455
Query: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082
+T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G
Sbjct: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 515
Query: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140
+ + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++
Sbjct: 516 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198
GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 633
Query: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
++ C L +F C A + P ++E C DAC C CLC+ +A YA C R
Sbjct: 634 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 689
Query: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311
HG V +R++ C+L CE + Y C C TC + PE G CVEG
Sbjct: 690 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 749
Query: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C CP T L A C+ C C + +PPG G+C C++G C
Sbjct: 750 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 802
Score = 214 bits (546), Expect = 1e-54
Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
+C P L C + G+ P N R + + G R C+A G H TFD
Sbjct: 32 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 91
Query: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081
GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+
Sbjct: 92 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 149
Query: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141
+ VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G
Sbjct: 150 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 207
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195
GLCG+ + D +DL + G L HSW+ P P LP P + N
Sbjct: 208 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 267
Query: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
+C ALL+P F CHA V P C D C S GD C A+A YA
Sbjct: 268 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 325
Query: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312
CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC
Sbjct: 326 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 382
Query: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
+CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C
Sbjct: 383 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 432
Score = 146 bits (369), Expect = 5e-34
Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)
Query: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144
W +R C HC E KA C A C +A ++ ++ C P
Sbjct: 336 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 386
Query: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199
G + DG A C + + PGS G+ A C+
Sbjct: 387 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 445
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250
H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++
Sbjct: 446 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
Query: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305
+ L QAG+V + Q ++P ++ + LS +L + +GV V DR G
Sbjct: 506 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 561
Query: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365
+ + VD T GLCG +NG +DDF+ P G FGNSW+ L A
Sbjct: 562 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 614
Query: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
PL D HL+A + V C L F C A +SP Y E C C
Sbjct: 615 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480
Q +CAT A Y C RRH + R R P C C + YS CV+
Sbjct: 670 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 718
Query: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531
C +C EA G G ++ R+ECV GC CP + + LCVP C C++
Sbjct: 719 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 778
Query: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567
Y PGD+ C C+DG C A C G
Sbjct: 779 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 814
Score = 98.2 bits (243), Expect = 2e-19
Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)
Query: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061
W C + RC +VTFDG Y+L + + TV + G
Sbjct: 2033 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2087
Query: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116
L V L T + H + R VTV+ V PP + G + G ++ T
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2145
Query: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172
+ + W ++V+ S + + GLCG DGDA+NDL + G + AE A
Sbjct: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205
Query: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225
SW++ G P C A C L+ + F+ CH VPP+
Sbjct: 2206 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2256
Query: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
E + D C A+ Y C + + WR + C C Y+AC
Sbjct: 2257 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2310
Query: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333
C P TC + P HCQV+ EGC C EGT+L H C+ A C C
Sbjct: 2311 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2368
Query: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357
W P +++ D G +C C
Sbjct: 2369 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
Query: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C + CE L P C G L QE+ C + CD D C E P
Sbjct: 2429 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2480
Query: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465
C + Q +T G + C CGD CP + C +G L
Sbjct: 2481 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2521
Score = 85.1 bits (209), Expect = 2e-15
Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913
C +LA C + TQ CT C E + C CP C +
Sbjct: 316 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 369
Query: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973
++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG
Sbjct: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 428
Query: 2974 KMACTSERCPVAC 2986
K C++ CP C
Sbjct: 429 KWECSTAVCPAEC 441
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)
Query: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207
Q R S+H P A+ P + LA VG LW R C+ + + TFD
Sbjct: 1996 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2051
Query: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258
G H Y+L+ + D VH+ + GH +T +V I
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2110
Query: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317
N V L P +G ++ G +++L+ + L +G + +
Sbjct: 2111 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170
Query: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374
Q GLCG+ +G +D G G A A F +SW++P S + C
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2227
Query: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433
D P C +++ F CH V P + E +
Sbjct: 2228 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2264
Query: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489
Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ +
Sbjct: 2265 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
Query: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526
G + E C + GC C G + LC+P A C C
Sbjct: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 73.9 bits (180), Expect = 4e-12
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087
+R+C+ G P G R Q R C + C+ E + C CP C
Sbjct: 323 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 370
Query: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146
C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+
Sbjct: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 429
Query: 4147 LSCTAQPCP 4155
C+ CP
Sbjct: 430 WECSTAVCP 438
Score = 72.4 bits (176), Expect = 1e-11
Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)
Query: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576
+ W S C P + S L P A+ +++ + +P L+P+ EQ R
Sbjct: 606 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 665
Query: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626
C G P LC LC G AC SC+ S +SP
Sbjct: 666 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 715
Query: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684
C PC G C++ + E+C +GG
Sbjct: 716 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 738
Query: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742
D R +C++G C CPP + Q CVP + C C + P +
Sbjct: 739 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 786
Query: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+C C + + C P CP + +CS + R RTCE
Sbjct: 787 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 836
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858
+Q NL ++ + PC GC CP G
Sbjct: 837 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 859
Query: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918
L H C P CPCT W + +E PG + C CVC G+F C+L
Sbjct: 860 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 906
Query: 4919 VDC 4921
C
Sbjct: 907 HPC 909
Score = 70.9 bits (172), Expect = 3e-11
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C
Sbjct: 362 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 421
Query: 3163 NCSCVSGLIANCSSWPCA 3180
C+C SG W C+
Sbjct: 422 TCTCTSG------KWECS 433
Score = 70.9 bits (172), Expect = 3e-11
Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867
C + S C C C L C ++ C GC CP L CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925
P C C Q + PPG + C C G SC P
Sbjct: 767 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 813
Query: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
G+ + + +L L + E + SGC C G R +PE+
Sbjct: 814 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 872
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
C C G+ + PG + C +C+C G CT H TC
Sbjct: 873 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 913
Score = 70.1 bits (170), Expect = 5e-11
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)
Query: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466
W E P G T S C G E EA + +AC +Y
Sbjct: 241 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 298
Query: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
A+C D + G W C + +RAC+ + GRP G TQ R C +
Sbjct: 299 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 345
Query: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584
C + + + C CP SC P + C + C C CP G + +DG CV PA
Sbjct: 346 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 400
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
C C++ G+ + PG VV C+ CTC +G +C CP
Sbjct: 401 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 438
Score = 70.1 bits (170), Expect = 5e-11
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)
Query: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
C C +G + W A E R C P Q T+ RQ C + C E
Sbjct: 301 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 349
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875
+ C CP C P A CV C GC CP G + +G CV P CPC
Sbjct: 350 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 404
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
H + PPG+V+ +C C C G + CS C
Sbjct: 405 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 70.1 bits (170), Expect = 5e-11
Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)
Query: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167
S G C + C Q + A L E C W G+ ++ G C +C +
Sbjct: 845 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 899
Query: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226
S L P A +TC ++ HYRTFDG + F+G C +L+ +D
Sbjct: 900 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
Query: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278
+++V + C G R + +G ++ +GN S + L E +W +
Sbjct: 946 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
Query: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
+ LV + + D+ ++ + + GQ GLCG ++ ++ P
Sbjct: 1005 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1057
Query: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396
FG+SW AVE DP + +++ EP A+ C
Sbjct: 1058 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1102
Query: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
LL F CH V ++ CL C G Q G + CA+ ++Y C + +
Sbjct: 1103 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1157
Query: 457 IRWRKPGFCERLCP 470
+ WR P RLCP
Sbjct: 1158 VDWRTP----RLCP 1167
Score = 69.7 bits (169), Expect = 7e-11
Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846
C+AP G S C G D E PP + + L P + CS
Sbjct: 716 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 775
Query: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901
G PGD+ P H +D C+++ A CP +F + H +
Sbjct: 776 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 826
Query: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958
R C Q + G C GC CP GL H +C +CPC G+ Y G
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 886
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ C+ C C G CT C C
Sbjct: 887 QV-MSPCHTCVCQRGSFQCTLHPCASTC 913
Score = 68.9 bits (167), Expect = 1e-10
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373
P PC + + C L+ C++ L T C S C ++W
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 315
Query: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433
CR L + A A+AG P R C + +C E + F ++ C
Sbjct: 316 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 358
Query: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491
+ C C S C D C GCYCP GL+ + GGC+ P EC C +H G
Sbjct: 359 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 409
Query: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519
PG ++ C C C G+ C++ C
Sbjct: 410 YPPGSVVKEDCNTCTCTSGKWECSTAVC 437
Score = 68.9 bits (167), Expect = 1e-10
Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)
Query: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351
LP +C A + EYSPC PC R+C DL C GC CPP
Sbjct: 700 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 757
Query: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
L + +CV CSC G + PG + HC C +G ++C P
Sbjct: 758 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 810
Query: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466
CP + + CS SR R C PC +G A G +AC
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
Query: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
CP + P SPC C+ CQ
Sbjct: 871 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 900
Query: 3523 STQCTDCGGGQSLHPCGQPC 3542
S QCT LHPC C
Sbjct: 901 SFQCT-------LHPCASTC 913
Score = 66.6 bits (161), Expect = 6e-10
Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)
Query: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
PC +C +H + C R P R + C C + PC PC
Sbjct: 674 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 720
Query: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592
R+CQDL+ C G G C C CP +Q LCVP C C +Q
Sbjct: 721 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 776
Query: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
G+ PG+ +C C G++ C
Sbjct: 777 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 803
Query: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710
+R P A CPAG+++ C
Sbjct: 804 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 826
Query: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764
+C + + G C GC CP+G +H AC +ECPC W
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCT---W------ 877
Query: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+ PGD++ S C C C G C+L C +G
Sbjct: 878 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 917
Score = 66.6 bits (161), Expect = 6e-10
Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)
Query: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533
+S+ EA+ E + CV E C R + G L + HCP R
Sbjct: 1957 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2016
Query: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593
+ G VR + C W CA C++ D ++TFDG + + + Y L
Sbjct: 2017 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2066
Query: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642
Q + + +L+ + + G CL V L TH+ R + V V+ Q
Sbjct: 2067 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702
V P + G + +++L Q+ W S + + Q GLCG
Sbjct: 2123 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2181
Query: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759
+ +D G V A F +QV S+L S T + + A C
Sbjct: 2182 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2232
Query: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812
+ ++ + F CHR V E F ++R V C L+ Y C +
Sbjct: 2233 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2285
Query: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863
WR CP +C Y+ C AC + C PE C LG GC C
Sbjct: 2286 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2342
Query: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917
G + C+P + C C +G R ++++ C + CQ C
Sbjct: 2343 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2402
Query: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964
PS PR L + A LL P C G+ C C PG LL
Sbjct: 2403 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2453
Query: 965 ----DERCVPPDLCPC 976
++ C P C C
Sbjct: 2454 THFQEDSCCPSYSCEC 2469
Score = 64.7 bits (156), Expect = 2e-09
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338
+ L +Y G Q + CT + Y+ C CP SC CV
Sbjct: 317 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 376
Query: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
C GCYCP G + G CV P C C G + PG+ + + CN CTC G+
Sbjct: 377 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 430
Query: 3399 NCTDLPCP 3406
C+ CP
Sbjct: 431 ECSTAVCP 438
Score = 64.3 bits (155), Expect = 3e-09
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)
Query: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105
C+ A CPAG V C++ R C + C GC CP+G L
Sbjct: 802 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 861
Query: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
C C CT +G + PG Q C+ C CQ G CT PC
Sbjct: 862 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
Score = 63.9 bits (154), Expect = 4e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)
Query: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639
VD PP G + P G+ C C G+V+V+ L +C
Sbjct: 778 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 835
Query: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697
N S S G C+ GC CP GLL H C ECPC + +PG ++ C
Sbjct: 836 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 894
Query: 2698 CVCEKGELLCQPGGCPLPC 2716
CVC++G C C C
Sbjct: 895 CVCQRGSFQCTLHPCASTC 913
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)
Query: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756
P PC + QG +C L C + S FTA+C D G+ +TW
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 315
Query: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813
CR R C P G RT Q + C A
Sbjct: 316 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 354
Query: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
E + A CP +C + +C GC+CP G + +G CV P +CPC
Sbjct: 355 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 406
Query: 1874 GARYWPGQRIKADCQLCICQDGR 1896
G Y PG +K DC C C G+
Sbjct: 407 GTLYPPGSVVKEDCNTCTCTSGK 429
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S +
Sbjct: 361 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 416
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G+ C CP C
Sbjct: 417 KEDCNTCTCTSGKWECSTAVCPAEC 441
Score = 62.0 bits (149), Expect = 1e-08
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125
G+ C P CP + +++C+ ELS R Q C GC C
Sbjct: 798 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 856
Query: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA
Sbjct: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 910
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513
PC GC CP+GLL C PEEC C G PGD++ C C C+RG
Sbjct: 849 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 903
Query: 4514 CTSQGC 4519
CT C
Sbjct: 904 CTLHPC 909
Score = 60.5 bits (145), Expect = 4e-08
Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)
Query: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751
C A +SP PC RTC + C G G + C ACP D
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 756
Query: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
T + V C CH G +L G H C
Sbjct: 757 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 806
Query: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859
P A C +F C+ TC+ ++ PC S GC CP+G + +
Sbjct: 807 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 865
Query: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C
Sbjct: 866 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 913
Score = 58.2 bits (139), Expect = 2e-07
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091
CA H A LC + +P C C A E C C R C DL C D
Sbjct: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
Query: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142
C +GC CP + Q CVP C C QG + PG + +C C
Sbjct: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 795
Query: 4143 QAGQLSC----TAQPCP 4155
+ G +SC A CP
Sbjct: 796 KDGVMSCDSRAPAAACP 812
Score = 53.9 bits (128), Expect = 4e-06
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)
Query: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734
+C CP SC R C+ C GC CP G + +DG CV + C C
Sbjct: 356 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 408
Query: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
P V+ DC CTC + C CP
Sbjct: 409 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 438
Score = 51.2 bits (121), Expect = 3e-05
Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)
Query: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863
CP C AC T+C P C Q G + +P CQ GC C G +LH +
Sbjct: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
Query: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
C+P C CT +P W +L+ Q Q P T++
Sbjct: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2397
Query: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970
VD P + GE+ L T CL Q+ C + C+PGH
Sbjct: 2398 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2452
Query: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029
Q C P CEC P L CE+ L P C Q +T G+
Sbjct: 2453 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2496
Query: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083
C C PE Q + LT RN T+ C L Q C + C
Sbjct: 2497 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2551
Query: 5084 STHVM----PEE--PYLQSQCDC 5100
T ++ P+ PY +CDC
Sbjct: 2552 GTALVEVWSPDRCCPYKSCECDC 2574
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
+R CA+ P G Q R C+ C+E Y EC CP SC H
Sbjct: 323 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 374
Query: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784
C +GC+CP G CV ECPC E T+ PG
Sbjct: 375 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 414
Query: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807
++ C C+C GK CS C
Sbjct: 415 VVKEDCNTCTCTSGKWECSTAVC 437
Score = 49.3 bits (116), Expect = 1e-04
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137
C K++ C A +C +L++P + C GC CP L ++CV
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
Query: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P C C +G YPPG + + +C C G+++ S P A
Sbjct: 767 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 809
Score = 48.9 bits (115), Expect = 1e-04
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472
SC E+ C +PC C S + C DL C GC CP L QA C
Sbjct: 706 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527
+P +C+C G+ PGD C C+ G + C S+ P +
Sbjct: 766 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 815
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
W S+CS G ++ PC Q ++Q C G++ + C+
Sbjct: 608 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 652
Query: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888
+ + Q C ++ C+ G C L H A C +H LP L
Sbjct: 653 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 700
Query: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947
P L+ ++ C P G T Q +A E C ++
Sbjct: 701 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 737
Query: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006
++ C GC C P + +QA CVP + C C G + PG + C
Sbjct: 738 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065
C G C C G+ V C + + +C Q L L +G
Sbjct: 794 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 848
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
C +S C+ CP + +L +C C
Sbjct: 849 PC------LSGCA--CPQGLLRHGDACFLPEECPC 875
Score = 46.6 bits (109), Expect = 6e-04
Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)
Query: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269
CA P T A L +P CS C QG D G HC C
Sbjct: 750 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 796
Query: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325
G+ S CD P A CP NC+ +
Sbjct: 797 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 834
Query: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384
C + +L V C GC CP G L +G C P C C G+ + PG ++
Sbjct: 835 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 890
Query: 3385 PDGCNHCTCLEGRLNCTDLPC 3405
P C+ C C G CT PC
Sbjct: 891 P--CHTCVCQRGSFQCTLHPC 909
Score = 45.4 bits (106), Expect = 0.001
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108
C C + C C P+ C Q+GI+ D QV +GC C +G++
Sbjct: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
Query: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159
C+P C CTD+ G A G + + C CQA L C P P P
Sbjct: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2409
Query: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211
C + + P C G + AP CR + CP SC
Sbjct: 2410 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2468
Query: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254
P LC + S + G CT C D ++PE
Sbjct: 2469 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2514
Score = 44.7 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018
A GC C P + G CV C C G + PGS +E C +C C SG+ C+
Sbjct: 377 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
Query: 5019 CSPLTCA 5025
P C+
Sbjct: 436 VCPAECS 442
Score = 43.1 bits (100), Expect = 0.007
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679
V PC +C D + +C CVEGC CPP L DT+ C+P ++C C
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 775
Query: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707
+ + +P + + C C+ G + C
Sbjct: 776 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 802
Score = 35.4 bits (80), Expect = 1.5
Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)
Query: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898
+T +PC + R S C P ++ C T+ QPC A + C
Sbjct: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2287
Query: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
+ CP LC + C C P TC G+ P CQ+ G+
Sbjct: 2288 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2341
Query: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012
L ++ C+ K ACT S P A G W+ +L C C
Sbjct: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2393
Query: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059
T P G C P E+ E L P P G C + C G
Sbjct: 2394 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2449
Query: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117
+R T S +C P C + C +D+ + G + C G
Sbjct: 2450 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2509
Query: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174
P C + + N +C P C C P C + L+
Sbjct: 2510 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2556
Query: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205
WSP P+ C C RCH
Sbjct: 2557 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2583
Score = 34.7 bits (78), Expect = 2.5
Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)
Query: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677
CQ G++ P LDP+ HC EGC C G +L H C+P ++C C
Sbjct: 2319 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2366
Query: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715
+GE W + L C Q C+ + + GCP P
Sbjct: 2367 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
Score = 33.9 bits (76), Expect = 4.3
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPP---CQPGCYCPKGLLEQAGGCIPPEEC---NC 4480
+ + AC SPC C + C+D+P C P C P+ L E C+ E+C
Sbjct: 1338 WRYDACASPCFQTCRDPRAAS-CRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1396
Query: 4481 WHTSAAGAGMTLAPGDRL 4498
W + A TL P L
Sbjct: 1397 WVPTEALGNETLPPSQGL 1414
Score = 32.7 bits (73), Expect = 9.6
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344
++L S +P QLL GL P + ++P T PGP + V
Sbjct: 1727 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1768
Query: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402
TTP+ Q +A TLP + PV P TPA + A P G P +LG
Sbjct: 1769 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
Score = 32.7 bits (73), Expect = 9.6
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
Query: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582
C + C C P++CQD G + CQ GC + G L + LC+P
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2358
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFS 3609
A C C +MG+P + S S
Sbjct: 2359 AKCAC---TDSMGVPRALGETWNSSLS 2382
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 546 bits (1408), Expect = e-154
Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249
C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210
Query: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
+G +E+ + A V+ G V ++ LQ L ++++ + D +
Sbjct: 211 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364
+ I + EL G T GLCG N P+DD + G L F +SW+ P G +
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
C PG ++ + C LL PF CHA VSP + +C C
Sbjct: 328 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 379
Query: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481
G C A Y +ACA+ ++ WR C C Y++C++
Sbjct: 380 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CP SC SC + CV GC CP GL + CV A CPC + Y PG
Sbjct: 433 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 487
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L +
Sbjct: 488 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 545
Query: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652
G + L++ C G+C+ ++SV L + L +G VL+ Q +P +
Sbjct: 546 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 605
Query: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711
+RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P
Sbjct: 606 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 665
Query: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771
G E++ F + ++ P + L PC H Q +++ AC++L +F C
Sbjct: 666 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 724
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830
+ P++ +C C C G CLC L+ YA C + G +R + C + C
Sbjct: 725 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 782
Query: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879
+EY C CG+ C PE CG G CV GC CP D + CVP +
Sbjct: 783 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 842
Query: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935
C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L
Sbjct: 843 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 899
Query: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988
TC+ N S A GC CP G + + C P+ CPC G+ Y P
Sbjct: 900 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 959
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047
+ C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S +
Sbjct: 960 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 1019
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106
F+V +N+ C +SG+ C K +++ + +++ V + P+ + +
Sbjct: 1020 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1072
Query: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + +
Sbjct: 1073 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1132
Query: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224
+ SW + CP+ D C +N R +A+ C LL +F +CH V
Sbjct: 1133 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1191
Query: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+
Sbjct: 1192 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1243
Score = 255 bits (651), Expect = 9e-67
Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
L CT HC +AF E + C +C ++ DGC CP G + D C
Sbjct: 412 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 467
Query: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG
Sbjct: 468 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 527
Query: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082
+T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G
Sbjct: 528 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 587
Query: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140
+ + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++
Sbjct: 588 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198
GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 705
Query: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
++ C L +F C A + P ++E C DAC C CLC+ +A YA C R
Sbjct: 706 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 761
Query: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311
HG V +R++ C+L CE + Y C C TC + PE G CVEG
Sbjct: 762 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 821
Query: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C CP T L A C+ C C + +PPG G+C C++G C
Sbjct: 822 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 874
Score = 214 bits (546), Expect = 1e-54
Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
+C P L C + G+ P N R + + G R C+A G H TFD
Sbjct: 104 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 163
Query: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081
GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+
Sbjct: 164 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 221
Query: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141
+ VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G
Sbjct: 222 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 279
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195
GLCG+ + D +DL + G L HSW+ P P LP P + N
Sbjct: 280 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 339
Query: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
+C ALL+P F CHA V P C D C S GD C A+A YA
Sbjct: 340 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 397
Query: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312
CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC
Sbjct: 398 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 454
Query: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
+CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C
Sbjct: 455 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 504
Score = 146 bits (369), Expect = 5e-34
Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)
Query: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144
W +R C HC E KA C A C +A ++ ++ C P
Sbjct: 408 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 458
Query: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199
G + DG A C + + PGS G+ A C+
Sbjct: 459 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 517
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250
H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++
Sbjct: 518 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 577
Query: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305
+ L QAG+V + Q ++P ++ + LS +L + +GV V DR G
Sbjct: 578 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 633
Query: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365
+ + VD T GLCG +NG +DDF+ P G FGNSW+ L A
Sbjct: 634 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 686
Query: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
PL D HL+A + V C L F C A +SP Y E C C
Sbjct: 687 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480
Q +CAT A Y C RRH + R R P C C + YS CV+
Sbjct: 742 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 790
Query: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531
C +C EA G G ++ R+ECV GC CP + + LCVP C C++
Sbjct: 791 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 850
Query: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567
Y PGD+ C C+DG C A C G
Sbjct: 851 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 886
Score = 98.2 bits (243), Expect = 2e-19
Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)
Query: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061
W C + RC +VTFDG Y+L + + TV + G
Sbjct: 2105 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2159
Query: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116
L V L T + H + R VTV+ V PP + G + G ++ T
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2217
Query: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172
+ + W ++V+ S + + GLCG DGDA+NDL + G + AE A
Sbjct: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277
Query: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225
SW++ G P C A C L+ + F+ CH VPP+
Sbjct: 2278 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2328
Query: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
E + D C A+ Y C + + WR + C C Y+AC
Sbjct: 2329 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2382
Query: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333
C P TC + P HCQV+ EGC C EGT+L H C+ A C C
Sbjct: 2383 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2440
Query: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357
W P +++ D G +C C
Sbjct: 2441 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2500
Query: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C + CE L P C G L QE+ C + CD D C E P
Sbjct: 2501 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2552
Query: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465
C + Q +T G + C CGD CP + C +G L
Sbjct: 2553 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2593
Score = 85.1 bits (209), Expect = 2e-15
Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913
C +LA C + TQ CT C E + C CP C +
Sbjct: 388 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 441
Query: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973
++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG
Sbjct: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 500
Query: 2974 KMACTSERCPVAC 2986
K C++ CP C
Sbjct: 501 KWECSTAVCPAEC 513
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)
Query: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207
Q R S+H P A+ P + LA VG LW R C+ + + TFD
Sbjct: 2068 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2123
Query: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258
G H Y+L+ + D VH+ + GH +T +V I
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2182
Query: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317
N V L P +G ++ G +++L+ + L +G + +
Sbjct: 2183 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2242
Query: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374
Q GLCG+ +G +D G G A A F +SW++P S + C
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2299
Query: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433
D P C +++ F CH V P + E +
Sbjct: 2300 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2336
Query: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489
Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ +
Sbjct: 2337 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2396
Query: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526
G + E C + GC C G + LC+P A C C
Sbjct: 2397 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 73.9 bits (180), Expect = 4e-12
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087
+R+C+ G P G R Q R C + C+ E + C CP C
Sbjct: 395 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 442
Query: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146
C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+
Sbjct: 443 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 501
Query: 4147 LSCTAQPCP 4155
C+ CP
Sbjct: 502 WECSTAVCP 510
Score = 72.4 bits (176), Expect = 1e-11
Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)
Query: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576
+ W S C P + S L P A+ +++ + +P L+P+ EQ R
Sbjct: 678 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 737
Query: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626
C G P LC LC G AC SC+ S +SP
Sbjct: 738 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 787
Query: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684
C PC G C++ + E+C +GG
Sbjct: 788 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 810
Query: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742
D R +C++G C CPP + Q CVP + C C + P +
Sbjct: 811 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 858
Query: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+C C + + C P CP + +CS + R RTCE
Sbjct: 859 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 908
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858
+Q NL ++ + PC GC CP G
Sbjct: 909 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 931
Query: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918
L H C P CPCT W + +E PG + C CVC G+F C+L
Sbjct: 932 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 978
Query: 4919 VDC 4921
C
Sbjct: 979 HPC 981
Score = 70.9 bits (172), Expect = 3e-11
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C
Sbjct: 434 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 493
Query: 3163 NCSCVSGLIANCSSWPCA 3180
C+C SG W C+
Sbjct: 494 TCTCTSG------KWECS 505
Score = 70.9 bits (172), Expect = 3e-11
Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867
C + S C C C L C ++ C GC CP L CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925
P C C Q + PPG + C C G SC P
Sbjct: 839 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 885
Query: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
G+ + + +L L + E + SGC C G R +PE+
Sbjct: 886 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 944
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
C C G+ + PG + C +C+C G CT H TC
Sbjct: 945 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 985
Score = 70.1 bits (170), Expect = 5e-11
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)
Query: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466
W E P G T S C G E EA + +AC +Y
Sbjct: 313 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 370
Query: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
A+C D + G W C + +RAC+ + GRP G TQ R C +
Sbjct: 371 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 417
Query: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584
C + + + C CP SC P + C + C C CP G + +DG CV PA
Sbjct: 418 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 472
Query: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
C C++ G+ + PG VV C+ CTC +G +C CP
Sbjct: 473 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 510
Score = 70.1 bits (170), Expect = 5e-11
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)
Query: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
C C +G + W A E R C P Q T+ RQ C + C E
Sbjct: 373 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 421
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875
+ C CP C P A CV C GC CP G + +G CV P CPC
Sbjct: 422 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 476
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
H + PPG+V+ +C C C G + CS C
Sbjct: 477 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 70.1 bits (170), Expect = 5e-11
Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)
Query: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167
S G C + C Q + A L E C W G+ ++ G C +C +
Sbjct: 917 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 971
Query: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226
S L P A +TC ++ HYRTFDG + F+G C +L+ +D
Sbjct: 972 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017
Query: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278
+++V + C G R + +G ++ +GN S + L E +W +
Sbjct: 1018 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076
Query: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
+ LV + + D+ ++ + + GQ GLCG ++ ++ P
Sbjct: 1077 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1129
Query: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396
FG+SW AVE DP + +++ EP A+ C
Sbjct: 1130 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1174
Query: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
LL F CH V ++ CL C G Q G + CA+ ++Y C + +
Sbjct: 1175 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1229
Query: 457 IRWRKPGFCERLCP 470
+ WR P RLCP
Sbjct: 1230 VDWRTP----RLCP 1239
Score = 69.7 bits (169), Expect = 7e-11
Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846
C+AP G S C G D E PP + + L P + CS
Sbjct: 788 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 847
Query: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901
G PGD+ P H +D C+++ A CP +F + H +
Sbjct: 848 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 898
Query: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958
R C Q + G C GC CP GL H +C +CPC G+ Y G
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 958
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ C+ C C G CT C C
Sbjct: 959 QV-MSPCHTCVCQRGSFQCTLHPCASTC 985
Score = 68.9 bits (167), Expect = 1e-10
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373
P PC + + C L+ C++ L T C S C ++W
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 387
Query: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433
CR L + A A+AG P R C + +C E + F ++ C
Sbjct: 388 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 430
Query: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491
+ C C S C D C GCYCP GL+ + GGC+ P EC C +H G
Sbjct: 431 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 481
Query: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519
PG ++ C C C G+ C++ C
Sbjct: 482 YPPGSVVKEDCNTCTCTSGKWECSTAVC 509
Score = 68.9 bits (167), Expect = 1e-10
Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)
Query: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351
LP +C A + EYSPC PC R+C DL C GC CPP
Sbjct: 772 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 829
Query: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
L + +CV CSC G + PG + HC C +G ++C P
Sbjct: 830 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 882
Query: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466
CP + + CS SR R C PC +G A G +AC
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 942
Query: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
CP + P SPC C+ CQ
Sbjct: 943 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 972
Query: 3523 STQCTDCGGGQSLHPCGQPC 3542
S QCT LHPC C
Sbjct: 973 SFQCT-------LHPCASTC 985
Score = 66.6 bits (161), Expect = 6e-10
Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)
Query: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
PC +C +H + C R P R + C C + PC PC
Sbjct: 746 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 792
Query: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592
R+CQDL+ C G G C C CP +Q LCVP C C +Q
Sbjct: 793 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 848
Query: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
G+ PG+ +C C G++ C
Sbjct: 849 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 875
Query: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710
+R P A CPAG+++ C
Sbjct: 876 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 898
Query: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764
+C + + G C GC CP+G +H AC +ECPC W
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCT---W------ 949
Query: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
G+ PGD++ S C C C G C+L C +G
Sbjct: 950 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 989
Score = 66.6 bits (161), Expect = 6e-10
Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)
Query: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533
+S+ EA+ E + CV E C R + G L + HCP R
Sbjct: 2029 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2088
Query: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593
+ G VR + C W CA C++ D ++TFDG + + + Y L
Sbjct: 2089 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2138
Query: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642
Q + + +L+ + + G CL V L TH+ R + V V+ Q
Sbjct: 2139 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702
V P + G + +++L Q+ W S + + Q GLCG
Sbjct: 2195 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2253
Query: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759
+ +D G V A F +QV S+L S T + + A C
Sbjct: 2254 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2304
Query: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812
+ ++ + F CHR V E F ++R V C L+ Y C +
Sbjct: 2305 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2357
Query: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863
WR CP +C Y+ C AC + C PE C LG GC C
Sbjct: 2358 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2414
Query: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917
G + C+P + C C +G R ++++ C + CQ C
Sbjct: 2415 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2474
Query: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964
PS PR L + A LL P C G+ C C PG LL
Sbjct: 2475 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2525
Query: 965 ----DERCVPPDLCPC 976
++ C P C C
Sbjct: 2526 THFQEDSCCPSYSCEC 2541
Score = 64.7 bits (156), Expect = 2e-09
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338
+ L +Y G Q + CT + Y+ C CP SC CV
Sbjct: 389 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 448
Query: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
C GCYCP G + G CV P C C G + PG+ + + CN CTC G+
Sbjct: 449 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 502
Query: 3399 NCTDLPCP 3406
C+ CP
Sbjct: 503 ECSTAVCP 510
Score = 64.3 bits (155), Expect = 3e-09
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)
Query: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105
C+ A CPAG V C++ R C + C GC CP+G L
Sbjct: 874 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 933
Query: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
C C CT +G + PG Q C+ C CQ G CT PC
Sbjct: 934 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 981
Score = 63.9 bits (154), Expect = 4e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)
Query: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639
VD PP G + P G+ C C G+V+V+ L +C
Sbjct: 850 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 907
Query: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697
N S S G C+ GC CP GLL H C ECPC + +PG ++ C
Sbjct: 908 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 966
Query: 2698 CVCEKGELLCQPGGCPLPC 2716
CVC++G C C C
Sbjct: 967 CVCQRGSFQCTLHPCASTC 985
Score = 62.4 bits (150), Expect = 1e-08
Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)
Query: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756
P PC + QG +C L C + S FTA+C D G+ +TW
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 387
Query: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813
CR R C P G RT Q + C A
Sbjct: 388 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 426
Query: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
E + A CP +C + +C GC+CP G + +G CV P +CPC
Sbjct: 427 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 478
Query: 1874 GARYWPGQRIKADCQLCICQDGR 1896
G Y PG +K DC C C G+
Sbjct: 479 GTLYPPGSVVKEDCNTCTCTSGK 501
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S +
Sbjct: 433 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 488
Query: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
+C+ C C G+ C CP C
Sbjct: 489 KEDCNTCTCTSGKWECSTAVCPAEC 513
Score = 62.0 bits (149), Expect = 1e-08
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125
G+ C P CP + +++C+ ELS R Q C GC C
Sbjct: 870 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 928
Query: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA
Sbjct: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 982
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513
PC GC CP+GLL C PEEC C G PGD++ C C C+RG
Sbjct: 921 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 975
Query: 4514 CTSQGC 4519
CT C
Sbjct: 976 CTLHPC 981
Score = 60.5 bits (145), Expect = 4e-08
Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)
Query: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751
C A +SP PC RTC + C G G + C ACP D
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 828
Query: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
T + V C CH G +L G H C
Sbjct: 829 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 878
Query: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859
P A C +F C+ TC+ ++ PC S GC CP+G + +
Sbjct: 879 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 937
Query: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C
Sbjct: 938 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 985
Score = 58.2 bits (139), Expect = 2e-07
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091
CA H A LC + +P C C A E C C R C DL C D
Sbjct: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808
Query: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142
C +GC CP + Q CVP C C QG + PG + +C C
Sbjct: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 867
Query: 4143 QAGQLSC----TAQPCP 4155
+ G +SC A CP
Sbjct: 868 KDGVMSCDSRAPAAACP 884
Score = 53.9 bits (128), Expect = 4e-06
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)
Query: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734
+C CP SC R C+ C GC CP G + +DG CV + C C
Sbjct: 428 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 480
Query: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
P V+ DC CTC + C CP
Sbjct: 481 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 510
Score = 51.2 bits (121), Expect = 3e-05
Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)
Query: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863
CP C AC T+C P C Q G + +P CQ GC C G +LH +
Sbjct: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424
Query: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
C+P C CT +P W +L+ Q Q P T++
Sbjct: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2469
Query: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970
VD P + GE+ L T CL Q+ C + C+PGH
Sbjct: 2470 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2524
Query: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029
Q C P CEC P L CE+ L P C Q +T G+
Sbjct: 2525 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2568
Query: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083
C C PE Q + LT RN T+ C L Q C + C
Sbjct: 2569 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2623
Query: 5084 STHVM----PEE--PYLQSQCDC 5100
T ++ P+ PY +CDC
Sbjct: 2624 GTALVEVWSPDRCCPYKSCECDC 2646
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
+R CA+ P G Q R C+ C+E Y EC CP SC H
Sbjct: 395 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 446
Query: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784
C +GC+CP G CV ECPC E T+ PG
Sbjct: 447 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 486
Query: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807
++ C C+C GK CS C
Sbjct: 487 VVKEDCNTCTCTSGKWECSTAVC 509
Score = 49.3 bits (116), Expect = 1e-04
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137
C K++ C A +C +L++P + C GC CP L ++CV
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 838
Query: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
P C C +G YPPG + + +C C G+++ S P A
Sbjct: 839 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 881
Score = 48.9 bits (115), Expect = 1e-04
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472
SC E+ C +PC C S + C DL C GC CP L QA C
Sbjct: 778 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527
+P +C+C G+ PGD C C+ G + C S+ P +
Sbjct: 838 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 887
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
W S+CS G ++ PC Q ++Q C G++ + C+
Sbjct: 680 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 724
Query: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888
+ + Q C ++ C+ G C L H A C +H LP L
Sbjct: 725 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 772
Query: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947
P L+ ++ C P G T Q +A E C ++
Sbjct: 773 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 809
Query: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006
++ C GC C P + +QA CVP + C C G + PG + C
Sbjct: 810 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065
C G C C G+ V C + + +C Q L L +G
Sbjct: 866 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 920
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
C +S C+ CP + +L +C C
Sbjct: 921 PC------LSGCA--CPQGLLRHGDACFLPEECPC 947
Score = 46.6 bits (109), Expect = 6e-04
Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)
Query: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269
CA P T A L +P CS C QG D G HC C
Sbjct: 822 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 868
Query: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325
G+ S CD P A CP NC+ +
Sbjct: 869 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 906
Query: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384
C + +L V C GC CP G L +G C P C C G+ + PG ++
Sbjct: 907 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 962
Query: 3385 PDGCNHCTCLEGRLNCTDLPC 3405
P C+ C C G CT PC
Sbjct: 963 P--CHTCVCQRGSFQCTLHPC 981
Score = 45.4 bits (106), Expect = 0.001
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108
C C + C C P+ C Q+GI+ D QV +GC C +G++
Sbjct: 2368 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2424
Query: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159
C+P C CTD+ G A G + + C CQA L C P P P
Sbjct: 2425 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2481
Query: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211
C + + P C G + AP CR + CP SC
Sbjct: 2482 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2540
Query: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254
P LC + S + G CT C D ++PE
Sbjct: 2541 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2586
Score = 44.7 bits (104), Expect = 0.002
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018
A GC C P + G CV C C G + PGS +E C +C C SG+ C+
Sbjct: 449 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 507
Query: 5019 CSPLTCA 5025
P C+
Sbjct: 508 VCPAECS 514
Score = 43.1 bits (100), Expect = 0.007
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679
V PC +C D + +C CVEGC CPP L DT+ C+P ++C C
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 847
Query: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707
+ + +P + + C C+ G + C
Sbjct: 848 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 874
Score = 35.4 bits (80), Expect = 1.5
Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)
Query: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898
+T +PC + R S C P ++ C T+ QPC A + C
Sbjct: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2359
Query: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
+ CP LC + C C P TC G+ P CQ+ G+
Sbjct: 2360 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2413
Query: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012
L ++ C+ K ACT S P A G W+ +L C C
Sbjct: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2465
Query: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059
T P G C P E+ E L P P G C + C G
Sbjct: 2466 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2521
Query: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117
+R T S +C P C + C +D+ + G + C G
Sbjct: 2522 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2581
Query: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174
P C + + N +C P C C P C + L+
Sbjct: 2582 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2628
Query: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205
WSP P+ C C RCH
Sbjct: 2629 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2655
Score = 34.7 bits (78), Expect = 2.5
Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)
Query: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677
CQ G++ P LDP+ HC EGC C G +L H C+P ++C C
Sbjct: 2391 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2438
Query: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715
+GE W + L C Q C+ + + GCP P
Sbjct: 2439 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2477
Score = 34.3 bits (77), Expect = 3.3
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLP---PCQPGCYCPKGLLEQAGGCIPPEEC---NC 4480
+ + AC SPC C + C+D+P C P C P+ L E C+ E+C
Sbjct: 1410 WRYDACASPCFQTCRDPRAAS-CRDVPRGRSCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1468
Query: 4481 WHTSAAGAGMTLAPGDRL 4498
W + A TL P L
Sbjct: 1469 WVPTEALGNETLPPSQGL 1486
Score = 32.7 bits (73), Expect = 9.6
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344
++L S +P QLL GL P + ++P T PGP + V
Sbjct: 1799 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1840
Query: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402
TTP+ Q +A TLP + PV P TPA + A P G P +LG
Sbjct: 1841 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1890
Score = 32.7 bits (73), Expect = 9.6
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
Query: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582
C + C C P++CQD G + CQ GC + G L + LC+P
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2430
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFS 3609
A C C +MG+P + S S
Sbjct: 2431 AKCAC---TDSMGVPRALGETWNSSLS 2454
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 483 bits (1243), Expect = e-135
Identities = 345/1190 (28%), Positives = 499/1190 (41%), Gaps = 127/1190 (10%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGA---ADSTWAVHLTPGDRCPQPGHCQR--VT 249
C++W H+ TFD Y F G C Y+ A A T++V L G G R V
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGP----DGSISRIIVE 100
Query: 250 MGPEEVLIQAGNVSVKG-------------QLVPEGQSWLLHGLSLQWLGDWLVLSGGLG 296
+G V + +SVK Q+ P GQS L L+ L
Sbjct: 101 LGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE-----------LE 149
Query: 297 VVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPG 356
+ V + + V+ + GQ GLCG ++G ++F+ G L
Sbjct: 150 LEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKF------------LEP 197
Query: 357 SESGCLDAVEVAQGCDPLGLID-ADVEPGHLR-AEAQDVCHQLLEGPFGQCHAQVSPAEY 414
+ L ++ DP + D+ H+R A+ +C QLL +C P
Sbjct: 198 HKFAALQKLD-----DPGEICTFQDIPSTHVRQAQHARICTQLLTLVAPECSVSKEP--- 249
Query: 415 HEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCE-RLCPGG 472
C +A + Q G Q + CAT + Y + C+ +R WR PG C CP
Sbjct: 250 ----FVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPAN 305
Query: 473 QLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGT----LCVPAAHCPCYY 528
Q+Y +C S C +C + SC C GC CP G N CVP CPC
Sbjct: 306 QVYQECGSACVKTCS----NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVL 361
Query: 529 CRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGC 588
Y PG+ C C C GRW C + CP C++ G TFD R Y F G C
Sbjct: 362 HGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT--C 419
Query: 589 RYSLVQDYV---KGQLLILLEH-GACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVG 644
Y L+Q G L+ + + G + + L A+ I + V NG+
Sbjct: 420 TYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKW 479
Query: 645 LPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPV--AYITLDPRHAHQVQGLCGTFTQ 702
LP+ ++V R +S L + L P+ AY+T+ P+ Q +GLCG F
Sbjct: 480 LPY-KTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNG 538
Query: 703 NQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAIL 762
+ DDF T G E + + F ++ G CP+ PC+ AE C++L
Sbjct: 539 DTTDDFTTSMGIAEGTASLFVDSWRA---GNCPAALERETDPCSMSQLNKVCAETHCSML 595
Query: 763 --HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASP-PWRN 819
+VF+ CH V+ PFY RC+ C + +C L Y C+ G WR+
Sbjct: 596 LRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRS 655
Query: 820 QT-LCPVMCPGGQEYRECAPACGQHC----GKPEDCGELGSCVAGCNCPLGLLWDPEGQC 874
C + C G + + AC + C + +C V GCNCP G + +G+C
Sbjct: 656 SVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGEC 715
Query: 875 VPPSLCPCQL-GARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAP-- 931
V + CPC L G + +T+ C C G +C R A C +
Sbjct: 716 VRKAQCPCILEGYKFILAEQSTVINGITCHCIN-GRLSCPQRPQMFLASCQAPKTFKSCS 774
Query: 932 --------GACLLTCDSPSANHSC-PAGSTDGCVCPPGTVL-LDERCVPPDLCPCRHSGQ 981
AC TC + +C P GCVC G D +CVPP+ CPC SG
Sbjct: 775 QSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGV 834
Query: 982 WYLPNATIQEDCNVCVCRGRQWHCT-GQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLL 1040
Y A + DC C C +W C G C G H +TFDG F + G CEY+L
Sbjct: 835 SYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYIL 894
Query: 1041 VREASGL------FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTP 1094
+ G+ F + +N+ CG SG+TC++A+ + L G V +L R TV G
Sbjct: 895 ATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSV-VLADRNYTVTGEE--- 950
Query: 1095 PKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDAS 1154
P V G + + + LTL+W+ +L++++ + + GLCG+F+G+
Sbjct: 951 PHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMK 1010
Query: 1155 NDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFT 1214
+D +R + + +SW+ SPLC + + PC++N R WA +C + F
Sbjct: 1011 DDFETRSRYVASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFA 1070
Query: 1215 LCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQ 1274
CH++V +YE C+ DACGCDSGGDCECLC A+A YA C G V WR+ C +
Sbjct: 1071 TCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIY 1130
Query: 1275 CEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVAC-----------VEGCF 1313
C + G + Q WH Q C +EGC+
Sbjct: 1131 CGFYNTHTQDGH--GEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCY 1178
Score = 201 bits (510), Expect = 2e-50
Identities = 167/583 (28%), Positives = 231/583 (39%), Gaps = 98/583 (16%)
Query: 923 CPRELVYAP--GACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD----ERCVPPDLCPC 976
CP VY AC+ TC +P HSC + T GC CP GTVL D CVP CPC
Sbjct: 302 CPANQVYQECGSACVKTCSNPQ--HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPC 359
Query: 977 RHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGAC 1036
G Y P C C C +W CT + G C G TFD + + G C
Sbjct: 360 VLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTC 419
Query: 1037 EYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPK 1096
Y+L++ L A SG++ ++ V VV++ R + ++ +
Sbjct: 420 TYILLQSPQ-LPEDGALMAVYDKSGVSHSETSLV----AVVYLSRQDKIVIS-----QDE 469
Query: 1097 VYTGPG------LSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQL----------SPQFRG 1140
V T G R +F STHL + + G ++VQL PQFRG
Sbjct: 470 VVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSF--GLELVVQLRPIFQAYVTVGPQFRG 527
Query: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLP-HPCTMNTHRAG 1199
+ GLCG+F+GD ++D + G+ E TA L SWR CP + PC+M+
Sbjct: 528 QTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN-CPAALERETDPCSMSQLNKV 586
Query: 1200 WARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECA 1257
A C LL+ +F CHA V P Y+ C+Y AC + +C+A+ Y C+
Sbjct: 587 CAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEE--TFPHICAALGDYVHACS 644
Query: 1258 RHGHHV-RWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCP 1315
G + WRS + C++ C G + C TC V+GC CP
Sbjct: 645 LRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCP 704
Query: 1316 EGTLLHG-GACLEPASCPCEWGRNSFPPGSVLQKDC---GNCTCQEGQWHCGGDGGHCEE 1371
+GT L+ G C+ A CPC F +L + TC
Sbjct: 705 DGTYLNQKGECVRKAQCPCILEGYKF----ILAEQSTVINGITCH--------------- 745
Query: 1372 LVPACAEGEALCQENGHCVPHGWLCDNQ-----DDCGDGSDEE--GCAAPGCGEGQMTCS 1424
C G C + P +L Q C S+ + AP C QM +
Sbjct: 746 ----CINGRLSCPQR----PQMFLASCQAPKTFKSCSQSSENKFGAACAPTC---QMLAT 794
Query: 1425 SGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPP 1467
C+P EP C +GL ADG+C+PP
Sbjct: 795 GVACVPTKC-------------EPGCVCAEGLYENADGQCVPP 824
Score = 149 bits (375), Expect = 9e-35
Identities = 112/375 (29%), Positives = 163/375 (43%), Gaps = 37/375 (9%)
Query: 1012 GRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVR 1071
G+C GA H+ TFD + + G C Y+ F + L G G + V
Sbjct: 43 GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG--SISRIIVE 100
Query: 1072 LEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLL---STHLGLTLLWDGGT 1128
L +VV + ++V + V YT GL + G + L L L ++W +
Sbjct: 101 LGASVVTVSEA-IISVKDIGVISLP-YTSNGLQITPFGQSVRLVAKQLELELEVVWGPDS 158
Query: 1129 RVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQG-VLEPTAELAAHSWRLSPLCPEPGDL 1187
++V + ++ G++ GLCG+FDG +N+ S +G LEP H + +PG++
Sbjct: 159 HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP------HKFAALQKLDDPGEI 212
Query: 1188 PHPCTM----NTHRAGWARAR-CGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDC 1242
CT +TH AR C LL + C V + C D G
Sbjct: 213 ---CTFQDIPSTHVRQAQHARICTQLLTLVAPEC--SVSKEPFVLSCQADVAAAPQPGPQ 267
Query: 1243 ECLCSAIATYADECARHGHHV-RWRSQELCSL-QCEGGQVYEACGPTCPPTCHEQHPEPG 1300
C+ ++ Y+ +C+ G V RWRS LCS+ QC QVY+ CG C TC +P+
Sbjct: 268 NSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTC--SNPQ-- 323
Query: 1301 WHCQVVACVEGCFCPEGTLL----HGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQ 1356
H +C GCFCPEGT+L + C+ CPC + PG V C C C
Sbjct: 324 -HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
Query: 1357 EGQWHCGGD--GGHC 1369
G+W C GHC
Sbjct: 383 LGRWVCTERPCPGHC 397
Score = 137 bits (346), Expect = 2e-31
Identities = 116/368 (31%), Positives = 157/368 (42%), Gaps = 29/368 (7%)
Query: 563 ECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGSC----LHA 618
+C+ G GH+ TFD Y F G ++ + L G + S L A
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGA 103
Query: 619 ISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSD 678
V++ + I ++D G + + GL I G SVR + L +V+WG D
Sbjct: 104 SVVTVSEAIISVKDIGVISLPYTSNGLQ-ITPFGQSVRLVAKQLEL----ELEVVWG-PD 157
Query: 679 PVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSED 738
+ ++ ++ Q+ GLCG F ++F++ G KF K P E
Sbjct: 158 SHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKF-----LEPHKFAALQKLDDPGEI 212
Query: 739 SALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGC-DPG-SDC 796
+TH R A C L + V EC V KEPF L C A V PG +
Sbjct: 213 CTFQDIPSTH-VRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNS 269
Query: 797 LCPVLSAYARRCAQEGAS-PPWRNQTLCPV-MCPGGQEYRECAPACGQHCGKPE-DCGEL 853
C LS Y+R+C+ G WR+ LC V CP Q Y+EC AC + C P+ C
Sbjct: 270 SCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSCS-- 327
Query: 854 GSCVAGCNCPLGLLWDP---EGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLW 910
SC GC CP G + + CVP + CPC L YAPG T+ C C C G W
Sbjct: 328 SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRC-TLGRW 386
Query: 911 NCTARHCP 918
CT R CP
Sbjct: 387 VCTERPCP 394
Score = 110 bits (274), Expect = 5e-23
Identities = 132/540 (24%), Positives = 203/540 (37%), Gaps = 79/540 (14%)
Query: 42 CASLDHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGA 101
CA+L YSR + P + R +PGLC + + P N+ + C G+
Sbjct: 271 CATLSEYSRQCSMVGQP------VRRWRSPGLCSVGQCPA------NQVYQEC-----GS 313
Query: 102 HCTEALAKASPEGHCFAMWQCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSS 161
C + + + C G+ + C P Q C +
Sbjct: 314 ACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCV--PVTQC-------PCVLHGA 364
Query: 162 RHLPGSASSPALLQPLAGAVGQLWSQHQRPS-ATCASWSGFHYRTFDGRHYHFLGRCTYL 220
+ PG + A Q +G+ W +RP C+ G TFD R Y F G CTY+
Sbjct: 365 MYAPGEVTIAAC-QTCRCTLGR-WVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYI 422
Query: 221 LAGAADSTWAVHLTPGDRCPQPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGL 280
L + P D + + E L+ +S + ++V + +
Sbjct: 423 LLQSPQ-------LPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNG 475
Query: 281 SLQWLGD---------------WLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGL 325
+WL + S GL +VV+L ++V + GQT+GLCG
Sbjct: 476 EAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
Query: 326 YNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGH 385
+NG DDF G A+ F +SWR C A+E + DP + +
Sbjct: 536 FNGDTTDDFTTSMGIAEGTASLFVDSWR----AGNCPAALE--RETDPCSMSQLN----- 584
Query: 386 LRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATF 443
+ A+ C LL F +CHA V+PA +++ C++ C E +CA
Sbjct: 585 -KVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQAC-------NYEETFPHICAAL 636
Query: 444 ASYVQACARRHIHI-RWRKP-GFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREEC 501
YV AC+ R + + WR C C G +S C +C ++ E C
Sbjct: 637 GDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATE-CHHSA 695
Query: 502 --VSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQLCN-PCVCRDGRWHCAQ 557
V GC CP G + N CV A CPC +++ + + C C +GR C Q
Sbjct: 696 VPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQ 755
Score = 84.7 bits (208), Expect = 2e-15
Identities = 101/371 (27%), Positives = 150/371 (40%), Gaps = 55/371 (14%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADS--TWAVHLTPGDRCPQPG-HC 245
+TC + H TFDG+ + F G C Y+LA G DS T+ + LT C G C
Sbjct: 866 STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKI-LTENVICGNSGVTC 924
Query: 246 QR---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLD 302
R + +G V++ N +V G+ P Q + G +L + D + + G + + +
Sbjct: 925 SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLGVTPG-ALSLVVD-ISIPGRYNLTLIWN 981
Query: 303 RTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCL 362
R +I I + GLCG +NG +DDF +A NSW+ C
Sbjct: 982 RHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCG 1038
Query: 363 DAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAY 422
D V DP L R+ A+ C + F CH++V Y+EAC+
Sbjct: 1039 DVSFVT---DPCSL------NAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDA 1089
Query: 423 CAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC 482
C G G + +C A+Y QAC + + + WR P FC C ++
Sbjct: 1090 C-----GCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ----- 1139
Query: 483 PPSCEAVGQGEEESCRE-ECV---SGCECPRGLFWNGTLCVPAAHCP-CYYCRQ-RYVPG 536
G GE + +E C C CP + VP ++ CY C Q Y
Sbjct: 1140 ------DGHGEYQYTQEANCTWHYQPCLCP-----SQPQSVPGSNIEGCYNCSQDEYF-- 1186
Query: 537 DTVRQLCNPCV 547
D +C PC+
Sbjct: 1187 DHEEGVCVPCM 1197
Score = 81.6 bits (200), Expect = 2e-14
Identities = 70/221 (31%), Positives = 87/221 (39%), Gaps = 30/221 (13%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLLHN-GTCVPPTACPC 4874
C S + +C C L A P GC CP G L+ G CV CPC
Sbjct: 664 CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS------LVDCQVPPG-E 4927
G L EQ+ TV+ N C C G SC L CQ P +
Sbjct: 724 ILE----GYKFILAEQS------TVI--NGITCHCINGRLSCPQRPQMFLASCQAPKTFK 771
Query: 4928 TWQQVAPGELGL-CEQTCLEMNATKTQSNCSSARAS-GCVCQPGHFRSQAGPCVPEDHCE 4985
+ Q + + G C TC +M AT C + GCVC G + + G CVP + C
Sbjct: 772 SCSQSSENKFGAACAPTC-QMLATGVA--CVPTKCEPGCVCAEGLYENADGQCVPPEECP 828
Query: 4986 CWHLGRPHLPGSEWQEACESCLCLSGRPVCTQ--HCSPLTC 5024
C G + G+E C +C C GR C Q HC P TC
Sbjct: 829 CEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHC-PSTC 868
Score = 80.5 bits (197), Expect = 4e-14
Identities = 45/141 (31%), Positives = 65/141 (46%), Gaps = 25/141 (17%)
Query: 2862 PGDTTCPGPHSQTRDCNT--QPC----------TAQCPENMLFRSAEQCHQEGGPCPRLC 2909
P +++C +R C+ QP QCP N ++ ++C G C + C
Sbjct: 266 PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVY---QEC---GSACVKTC 319
Query: 2910 LTQGPGIECTGFCAPGCTCPPGLFLH----NASCLPRSQCPCQLHGQLYASGAMARLDSC 2965
P C+ C GC CP G L+ N +C+P +QCPC LHG +YA G + + +C
Sbjct: 320 --SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT-IAAC 376
Query: 2966 NNCTCVSGKMACTSERCPVAC 2986
C C G+ CT CP C
Sbjct: 377 QTCRCTLGRWVCTERPCPGHC 397
Score = 78.6 bits (192), Expect = 2e-13
Identities = 63/227 (27%), Positives = 83/227 (36%), Gaps = 46/227 (20%)
Query: 1190 PCTMNTHRAGWARA--RCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSG------GD 1241
PCT NT + ++A R L T CH P D C C G G+
Sbjct: 663 PCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP--------VDGCNCPDGTYLNQKGE 714
Query: 1242 C----ECLC-------------SAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEAC 1284
C +C C + I C R Q + C+ + +++C
Sbjct: 715 CVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLA-SCQAPKTFKSC 773
Query: 1285 --------GPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHG-GACLEPASCPCEW 1335
G C PTC Q G C C GC C EG + G C+ P CPCE+
Sbjct: 774 SQSSENKFGAACAPTC--QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEF 831
Query: 1336 GRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEAL 1382
S+P G+ L DC C+C G+W C G HC EG +
Sbjct: 832 SGVSYPGGAELHTDCRTCSCSRGRWAC-QQGTHCPSTCTLYGEGHVI 877
Score = 77.8 bits (190), Expect = 3e-13
Identities = 65/250 (26%), Positives = 89/250 (35%), Gaps = 62/250 (24%)
Query: 4671 DTVFTLDCANQCPHSCADLWDRVQCLQGPCRP--GCRCPPGQ-LVQDGRCVPISSCRCGL 4727
+T F+ + + C +C L DR P GC CP G L Q G CV + C C L
Sbjct: 667 NTTFSYN-SQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCIL 725
Query: 4728 PSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERH 4787
+ Q+ ++ C C+N L CP + P +SC AP
Sbjct: 726 EGYKF---ILAEQSTVINGITCHCINGRLSCPQR------PQMFLASCQAP--------- 767
Query: 4788 RTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQE 4847
+ C + + +ACA +C L G CV
Sbjct: 768 ----------------------KTFKSCSQSSENKFGAACAPTCQMLA----TGVACVPT 801
Query: 4848 PCQPGCGCPGGQLLH-NGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTR 4906
C+PGC C G + +G CVPP CPC E P G L +C
Sbjct: 802 KCEPGCVCAEGLYENADGQCVPPEECPC-------------EFSGVSYPGGAELHTDCRT 848
Query: 4907 CVCHGGAFSC 4916
C C G ++C
Sbjct: 849 CSCSRGRWAC 858
Score = 71.2 bits (173), Expect = 2e-11
Identities = 66/266 (24%), Positives = 85/266 (31%), Gaps = 78/266 (29%)
Query: 2798 RSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPS------------IWGLWAPWSTCSAP 2845
R + + P+P C A E P +C +WG + C+ P
Sbjct: 604 RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
Query: 2846 CDGGI------QTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCT-----------AQCP- 2887
C G Q R+C SL+ T C CN T AQCP
Sbjct: 664 CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
Query: 2888 --ENMLFRSAEQ--------CH----------------------------------QEGG 2903
E F AEQ CH + G
Sbjct: 724 ILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGA 783
Query: 2904 PCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLH-NASCLPRSQCPCQLHGQLYASGAMAR 2961
C C G+ C C PGC C GL+ + + C+P +CPC+ G Y GA
Sbjct: 784 ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELH 843
Query: 2962 LDSCNNCTCVSGKMAC-TSERCPVAC 2986
D C C+C G+ AC CP C
Sbjct: 844 TD-CRTCSCSRGRWACQQGTHCPSTC 868
Score = 70.5 bits (171), Expect = 4e-11
Identities = 40/113 (35%), Positives = 52/113 (46%), Gaps = 12/113 (10%)
Query: 4054 NPMPCEAG-CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGS----LEQD 4108
+P C G CPA C + C + CS+ Q C C GC CP+G+ L +
Sbjct: 293 SPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSS--CTFGCFCPEGTVLNDLSNN 348
Query: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCA 4161
CVP+ C C G +APG AC C C G+ CT +PC P HC+
Sbjct: 349 HTCVPVTQCPCV-LHGAMYAPGEVTIAACQTCRCTLGRWVCTERPC--PGHCS 398
Score = 69.3 bits (168), Expect = 9e-11
Identities = 60/212 (28%), Positives = 78/212 (36%), Gaps = 53/212 (25%)
Query: 1730 QNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPC------RGTMTRQRQCHSPQNG- 1782
+ C ++ C +A PVDG C+ P +G R+ QC G
Sbjct: 679 RTCLSLSDRATECHHSAVPVDG----------CNCPDGTYLNQKGECVRKAQCPCILEGY 728
Query: 1783 ------------GRTCAALPGGLHSTRQTKPCPQDGCPN---ATCSGELMFQPC------ 1821
G TC + G L CPQ P A+C F+ C
Sbjct: 729 KFILAEQSTVINGITCHCINGRLS-------CPQR--PQMFLASCQAPKTFKSCSQSSEN 779
Query: 1822 ---APCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYW 1878
A C TC ++ V C P C PGC C EG ++G CV P +CPC G Y
Sbjct: 780 KFGAACAPTCQMLATGVACVPT-KC-EPGCVCAEGLYENADGQCVPPEECPCEFSGVSYP 837
Query: 1879 PGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
G + DC+ C C GR C+ C C
Sbjct: 838 GGAELHTDCRTCSCSRGR-WACQQGTHCPSTC 868
Score = 65.9 bits (159), Expect = 1e-09
Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 9/104 (8%)
Query: 3306 CPVTNCTAIEGAEYSPCGPPCPRSCDDLVH-CVWRCQPGCYCPPGQVLS--SNGAICVQP 3362
C V C A + Y CG C ++C + H C C GC+CP G VL+ SN CV
Sbjct: 297 CSVGQCPANQ--VYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPV 354
Query: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
C C+ L G + PG C C C GR CT+ PCP
Sbjct: 355 TQCPCV--LHGAMYAPGEVTIA--ACQTCRCTLGRWVCTERPCP 394
Score = 65.9 bits (159), Expect = 1e-09
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 8/97 (8%)
Query: 3088 GMCPRDKQWLDCAQGPASCAELSAPRGT-NQTCHPGCHCPSGMLLL----NNVCVPTQDC 3142
G CP ++ + +C G A S P+ + + +C GC CP G +L N+ CVP C
Sbjct: 300 GQCPANQVYQEC--GSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQC 357
Query: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
PC G +Y PG + C+ C C G C+ PC
Sbjct: 358 PCVLHGAMYAPGEVTIAACQTCRCTLGRWV-CTERPC 393
Score = 64.3 bits (155), Expect = 3e-09
Identities = 54/178 (30%), Positives = 74/178 (41%), Gaps = 31/178 (17%)
Query: 2544 SQSCFVQACPVAGAWAMWEAWGPCSVSCGG-GHQSRQRSCVDPPPKNGGAPCPGASQERA 2602
S+ FV +C A A GP + SC SRQ S V P + +P
Sbjct: 246 SKEPFVLSCQADVAAAPQP--GPQNSSCATLSEYSRQCSMVGQPVRRWRSP--------- 294
Query: 2603 PCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGL 2662
GL CS G C +VY C +C +P+ SCS C GC CP G
Sbjct: 295 --GL--CSVG-QCPANQVYQECGSA-------CVKTCSNPQ--HSCSSSCTFGCFCPEGT 340
Query: 2663 LLHDT----RCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPC 2716
+L+D C+P+++CPC++ + PG + C C C G +C CP C
Sbjct: 341 VLNDLSNNHTCVPVTQCPCVLHGAMYAPG-EVTIAACQTCRCTLGRWVCTERPCPGHC 397
Score = 64.3 bits (155), Expect = 3e-09
Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 15/102 (14%)
Query: 4422 SCTPPFEFHAC--------GSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGG-C 4472
SC P F +C G+ CA C + C C+PGC C +GL E A G C
Sbjct: 763 SCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTK-CEPGCVCAEGLYENADGQC 821
Query: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHC 4514
+PPEEC C +G++ G L C+ C C RG C
Sbjct: 822 VPPEECPC-----EFSGVSYPGGAELHTDCRTCSCSRGRWAC 858
Score = 62.0 bits (149), Expect = 1e-08
Identities = 54/186 (29%), Positives = 73/186 (39%), Gaps = 36/186 (19%)
Query: 1718 SRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCH 1777
+R C+ L LV C S+ F +C D V + P G + C
Sbjct: 229 ARICTQLLTLVAPECS----VSKEPFVLSCQAD----------VAAAPQPGP--QNSSCA 272
Query: 1778 SPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVT 1836
+ R C+ + + R C CP ++Q C + C TC +
Sbjct: 273 TLSEYSRQCSMVGQPVRRWRSPGLCSVGQCP-----ANQVYQECGSACVKTCSN------ 321
Query: 1837 CPPDWPCGSP---GCWCPEGQVLG---SEGWCVWPRQCPCLVDGARYWPGQRIKADCQLC 1890
P C S GC+CPEG VL + CV QCPC++ GA Y PG+ A CQ C
Sbjct: 322 --PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC 379
Query: 1891 ICQDGR 1896
C GR
Sbjct: 380 RCTLGR 385
Score = 60.5 bits (145), Expect = 4e-08
Identities = 70/283 (24%), Positives = 96/283 (33%), Gaps = 90/283 (31%)
Query: 3526 CT-DCGGGQSLHPCGQPCPRSCQDLSPGSV-CQPGSVGCQPTCGCPLGQ-LSQDGLCVPP 3582
CT C G + Q C R+C LS + C +V C CP G L+Q G CV
Sbjct: 660 CTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDG-CNCPDGTYLNQKGECVRK 718
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDC 3642
A C C + G +F E V+ G C C+ G L C + P
Sbjct: 719 AQCPCILE--------------GYKFIL---AEQSTVINGI--TCHCINGRLSCPQRP-- 757
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRL 3702
Q+ C P + ++CS
Sbjct: 758 -----------------------QMFLASCQAP------KTFKSCSQS------------ 776
Query: 3703 YRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA-CV--QECPCVLTAWL 3759
E + G C +C + V C CE GC C EG +++ CV +ECPC +
Sbjct: 777 -SENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSG-- 833
Query: 3760 LQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
+ PG G L T C CSC+ G+ +C
Sbjct: 834 -------VSYPG-----------GAELHTDCRTCSCSRGRWAC 858
Score = 59.3 bits (142), Expect = 1e-07
Identities = 53/182 (29%), Positives = 72/182 (39%), Gaps = 46/182 (25%)
Query: 3633 ILQCQ-EVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQV 3691
+L CQ +V P PG +S SC + SR+C+ P R+ R S +
Sbjct: 251 VLSCQADVAAAPQPGPQNS---------SCATLSEY-SRQCSM--VGQPVRRWR--SPGL 296
Query: 3692 CREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF------QHRL 3745
C CPA ++Y+EC G C +C++ Q C S C GC CPEGT H
Sbjct: 297 CSVGQCPANQVYQEC--GSACVKTCSN--PQHSC-SSSCTFGCFCPEGTVLNDLSNNHTC 351
Query: 3746 ACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLD 3805
V +CPCVL G G+ +C C C G+ C+
Sbjct: 352 VPVTQCPCVL--------------------HGAMYAPGEVTIAACQTCRCTLGRWVCTER 391
Query: 3806 DC 3807
C
Sbjct: 392 PC 393
Score = 57.0 bits (136), Expect = 5e-07
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 14/113 (12%)
Query: 4916 CSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPG---HFR 4972
CS+ C P + +Q+ C +TC + Q +CSS+ GC C G +
Sbjct: 297 CSVGQC--PANQVYQECGSA----CVKTC-----SNPQHSCSSSCTFGCFCPEGTVLNDL 345
Query: 4973 SQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
S CVP C C G + PG AC++C C GR VCT+ P C+
Sbjct: 346 SNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCS 398
Score = 57.0 bits (136), Expect = 5e-07
Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 20/109 (18%)
Query: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLH----NGTCVPPTAC 4872
+CP QV C ++C C + Q C GC CP G +L+ N TCVP T C
Sbjct: 301 QCPANQVYQECGSACVKTCSNPQHSC---SSSCTFGCFCPEGTVLNDLSNNHTCVPVTQC 357
Query: 4873 PCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
PC H + PG V C C C G + C+ C
Sbjct: 358 PCVLHGAMYA-------------PGEVTIAACQTCRCTLGRWVCTERPC 393
Score = 56.2 bits (134), Expect = 8e-07
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 16/139 (11%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGP-GIECTGFCAP--GCTCPPGLFLHN-A 2937
CT C N F Q C R CL+ EC P GC CP G +L+
Sbjct: 660 CTIPCTGNTTFSYNSQA------CERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKG 713
Query: 2938 SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSE-RCPVACGWSPWTLWSL 2996
C+ ++QCPC L G + + + + C C++G+++C + +A +P T
Sbjct: 714 ECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTF--- 770
Query: 2997 CSCSCNVGIRRRFRAGTAP 3015
SC+ +F A AP
Sbjct: 771 --KSCSQSSENKFGAACAP 787
Score = 55.8 bits (133), Expect = 1e-06
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 17/104 (16%)
Query: 3090 CPRDKQWLDCAQGP-----ASCAELSAPRGTNQTC-----HPGCHCPSGMLL-LNNVCVP 3138
C K + C+Q A+CA T C PGC C G+ + CVP
Sbjct: 764 CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
Query: 3139 TQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEG 3182
++CPC G YP G+ + C CSC G W C +G
Sbjct: 824 PEECPCEFSGVSYPGGAELHTDCRTCSCSRG------RWACQQG 861
Score = 54.7 bits (130), Expect = 2e-06
Identities = 32/108 (29%), Positives = 41/108 (37%), Gaps = 13/108 (12%)
Query: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGL----LEQAGGCI 4473
CS C + CGS C C+ C C GC+CP+G L C+
Sbjct: 297 CSVGQCPANQVYQECGSACVKTCSN--PQHSCSS--SCTFGCFCPEGTVLNDLSNNHTCV 352
Query: 4474 PPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521
P +C C G APG+ C+ C C G CT + C G
Sbjct: 353 PVTQCPC-----VLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPG 395
Score = 54.7 bits (130), Expect = 2e-06
Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 23/136 (16%)
Query: 2589 NGGAPCPGASQE-----RAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPK 2643
NG CP Q +AP + CS ++ + G C P+C
Sbjct: 748 NGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAA--------------CAPTCQMLA 793
Query: 2644 ANRSC-SGHCVEGCRCPPGLLLH-DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCE 2701
+C C GC C GL + D +C+P ECPC + +PG + L +C C C
Sbjct: 794 TGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSG-VSYPGGAELHTDCRTCSCS 852
Query: 2702 KGELLCQPG-GCPLPC 2716
+G CQ G CP C
Sbjct: 853 RGRWACQQGTHCPSTC 868
Score = 54.3 bits (129), Expect = 3e-06
Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 4075 CPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQ-DGGCVPIGHCDCTDAQGHSWAPGSQH 4133
C C L G+ C + C+ GC C +G E DG CVP C C + G S+ G++
Sbjct: 785 CAPTCQMLATGVACVPTK-CEPGCVCAEGLYENADGQCVPPEECPC-EFSGVSYPGGAEL 842
Query: 4134 QDACNNCSCQAGQLSCTAQPCPPPTHC 4160
C CSC G+ + C THC
Sbjct: 843 HTDCRTCSCSRGRWA-----CQQGTHC 864
Score = 53.5 bits (127), Expect = 5e-06
Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 16/110 (14%)
Query: 4659 CNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQD---- 4714
C+ G CP + +C + C +C++ + C C GC CP G ++ D
Sbjct: 297 CSVGQCPANQVYQ-----ECGSACVKTCSN--PQHSC-SSSCTFGCFCPEGTVLNDLSNN 348
Query: 4715 GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
CVP++ C C L A AP + CQ C C VC + CP
Sbjct: 349 HTCVPVTQCPCVLHGAM----YAPGEVTIAACQTCRCTLGRWVCTERPCP 394
Score = 52.8 bits (125), Expect = 9e-06
Identities = 74/329 (22%), Positives = 105/329 (31%), Gaps = 80/329 (24%)
Query: 3352 LSSNGAICVQPGHCSCLDLLTG---QRHH------PGARLARPDGCNH-------CTCLE 3395
+S +C + HCS L L TG +R H P + CN+ C L
Sbjct: 580 MSQLNKVCAET-HCSML-LRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALG 637
Query: 3396 GRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTP-----------QHGG 3444
++ L + GW S C+ PC G T + AC H
Sbjct: 638 DYVHACSLRGVLLWGWR--SSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSA 695
Query: 3445 APCTG-EAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTP 3503
P G + +Q+ C A CP C+ + ++ + T
Sbjct: 696 VPVDGCNCPDGTYLNQKGECVRKAQCP----------------CILEGYKF-ILAEQSTV 738
Query: 3504 EGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQP--------CPRSCQDLSPGSVC 3555
G C + + Q C ++ C Q C +CQ L+ G C
Sbjct: 739 INGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVAC 798
Query: 3556 QPGSVGCQPTCGCPLGQLSQ-DGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESL 3614
P C+P C C G DG CVPP C C++ S S
Sbjct: 799 VPTK--CEPGCVCAEGLYENADGQCVPPEECPCEF--------------------SGVSY 836
Query: 3615 EPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
G + C C+C G CQ+ CP
Sbjct: 837 PGGAELHTDCRTCSCSRGRWACQQGTHCP 865
Score = 52.0 bits (123), Expect = 2e-05
Identities = 52/184 (28%), Positives = 59/184 (32%), Gaps = 42/184 (22%)
Query: 3464 PSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENS 3523
P +C D A P P C S SR CS P PG + +
Sbjct: 249 PFVLSCQADVAAAPQ-PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQ------ 301
Query: 3524 TQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCP----LGQLSQDGLC 3579
C Q CG C ++C + P C S C C CP L LS + C
Sbjct: 302 -----CPANQVYQECGSACVKTCSN--PQHSC---SSSCTFGCFCPEGTVLNDLSNNHTC 351
Query: 3580 VPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEV 3639
VP C C GAM PGEV C C C G C E
Sbjct: 352 VPVTQCPCVLH-GAM-------------------YAPGEVTIAACQTCRCTLGRWVCTER 391
Query: 3640 PDCP 3643
P CP
Sbjct: 392 P-CP 394
Score = 50.8 bits (120), Expect = 3e-05
Identities = 55/219 (25%), Positives = 75/219 (34%), Gaps = 24/219 (10%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIV-CQDDQVCQKGCRCPKGS-LEQDGGCVPIG 4115
C C + C R C L + C V GC CP G+ L Q G CV
Sbjct: 660 CTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKA 719
Query: 4116 HCDCTDAQGHSWAPGSQHQDACN--NCSCQAGQLSCTAQP------CPPPTHCAWSHWSA 4167
C C +G+ + Q N C C G+LSC +P C P S+
Sbjct: 720 QCPCI-LEGYKFILAEQ-STVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSS 777
Query: 4168 WSPCSHSCGPRGQQSRF------RSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRS 4221
+ +C P Q G E E + Q P CP + +
Sbjct: 778 ENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECP---CEFSGV 834
Query: 4222 RTLGDSWLQGECQRCSCTPEGVICED-TECAVPEAWTLW 4259
G + L +C+ CSC+ C+ T C P TL+
Sbjct: 835 SYPGGAELHTDCRTCSCSRGRWACQQGTHC--PSTCTLY 871
Score = 50.4 bits (119), Expect = 4e-05
Identities = 65/248 (26%), Positives = 83/248 (33%), Gaps = 34/248 (13%)
Query: 3287 LGDYCEGPRAQGEVCQALPCPVTNCT--AIEGAEYSPCGPPCPRSCDDLVHCVWRCQ--- 3341
LGDY +G + V NCT +S C R+C L C
Sbjct: 636 LGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSA 695
Query: 3342 ---PGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
GC CP G L+ G CV+ C C+ L G + + +G C C+ GRL
Sbjct: 696 VPVDGCNCPDGTYLNQKGE-CVRKAQCPCI--LEGYKFILAEQSTVINGIT-CHCINGRL 751
Query: 3399 NCTDLP------CPVPGGW--CPWSEWTMCSQPCRGQTRSRSRACAC-PTPQHGGAPCTG 3449
+C P C P + C S C + + AC PT G C
Sbjct: 752 SCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAE 811
Query: 3450 EAGE--AGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPP-TPEGG 3506
E G E CP C G P G D R+ +CSR + G
Sbjct: 812 GLYENADGQCVPPEECP----CEFSGVSYPGGAELHTDC------RTCSCSRGRWACQQG 861
Query: 3507 RPCPGNHT 3514
CP T
Sbjct: 862 THCPSTCT 869
Score = 45.4 bits (106), Expect = 0.001
Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 17/117 (14%)
Query: 4650 CREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPG 4709
C+ P +SC+ ++ + F CA +C L V C+ C PGC C G
Sbjct: 764 CQAPKTFKSCS-------QSSENKFGAACAP----TCQMLATGVACVPTKCEPGCVCAEG 812
Query: 4710 QLVQ-DGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPH-QECP 4764
DG+CVP C C + + DC+ C+C C CP
Sbjct: 813 LYENADGQCVPPEECPCEFSGVS----YPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
Score = 40.0 bits (92), Expect = 0.060
Identities = 41/149 (27%), Positives = 59/149 (39%), Gaps = 25/149 (16%)
Query: 3122 GCHCPSGMLL-LNNVCVPTQDCPCAHEGH--LYPPGSTVVRPCENCSCVSGLIANCSSWP 3178
GC+CP G L CV CPC EG+ + STV+ C C++G + +C P
Sbjct: 700 GCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGI-TCHCINGRL-SCPQRP 757
Query: 3179 CAEGEPTWSPWTPWSQCSASCGPARCHRHRF---CARSPSAVPSTVAPLPLPATPTPLCS 3235
+P T + CS S ++F CA + + + VA +P P +C+
Sbjct: 758 QMFLASCQAPKT-FKSCSQS------SENKFGAACAPTCQMLATGVACVPTKCEPGCVCA 810
Query: 3236 G----------PEAEEEPCLLQGCDRAGG 3254
EE PC G GG
Sbjct: 811 EGLYENADGQCVPPEECPCEFSGVSYPGG 839
Score = 35.8 bits (81), Expect = 1.1
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 16/83 (19%)
Query: 2635 CPPSCLDPKANRSCSGHC---VEGCRCPPGLLLHDT-RCLPLSECPCLVGEELKWPGVSF 2690
C +CL + H V+GC CP G L+ C+ ++CPC++ G F
Sbjct: 677 CERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCIL------EGYKF 730
Query: 2691 LLG------NCSQCVCEKGELLC 2707
+L N C C G L C
Sbjct: 731 ILAEQSTVINGITCHCINGRLSC 753
Score = 33.9 bits (76), Expect = 4.3
Identities = 38/156 (24%), Positives = 52/156 (33%), Gaps = 13/156 (8%)
Query: 2241 CASGECVLRGGPCDGVLDCEDGS---DEEG-CVLLPEGTGRFHSTAKTLALSSAQPGQLL 2296
C S + G +G +C EEG CV T T L + ++P Q+
Sbjct: 1162 CPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTTPQPPTTPQLPTTGSRPTQV- 1220
Query: 2297 HWPREG-------LAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIP 2349
WP G L+ T P +P SPT+T + S P TT +
Sbjct: 1221 -WPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVT 1279
Query: 2350 QMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGP 2385
LPP + VT AT + P
Sbjct: 1280 PQATSGLPPTATLRSTATKPTVTQATTRATASTASP 1315
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 463 bits (1191), Expect = e-129
Identities = 323/1129 (28%), Positives = 487/1129 (43%), Gaps = 127/1129 (11%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLA---GAADSTWAVHLTPGDRCPQPGH-CQR--- 247
C +W +H+ TFDG +Y+F G C+Y+ A G + + V + +C + C R
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSIS 123
Query: 248 -VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
EE+ I + G + Q+ + + ++ L D++++ G + D
Sbjct: 124 LFFSNQEEIRIYGHEIKKNGISLTLPQT--IGQIFIEKLADYILVKTTFGFSLAWDGISG 181
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSW--RLPGSESGCLDA 364
I + + + G++ GLCG YN DDF+ A F NSW + P L
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTP 241
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDV-CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
+ C G EA C LL+ PF CH + P Y +C+ C
Sbjct: 242 SDFPNPC----------SSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLC 291
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQLYSDCVSL 481
+ + C Y +AC+ I+ WR C C ++ DC+S
Sbjct: 292 --------KTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343
Query: 482 CPPSCEAVGQGEEESC---REECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CPP+C E+ C C+ GC CP GL + C+ +CPC + Y G
Sbjct: 344 CPPTCTF-----EKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSK 398
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
+ Q C CVC G W+C + CP +C+V GD H+ TFDGR YSF G C+Y LV+ K
Sbjct: 399 IEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIG--MCQYILVKGTGK 456
Query: 599 GQLLILLEHGACDAG---SCLHAISVSLED---THIQLRDSGAVLVN-GQDVGLPWIGAE 651
+ I L+ C+ CL +I++ LED + L G +L + Q L I
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI--- 513
Query: 652 GLSVRRASSAFLLLRWP-GAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLT 710
+ ++ SS F+LL+ G ++L+ + YI L + GLCGTF N +DDFL+
Sbjct: 514 -VEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLS 572
Query: 711 PAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQEC 770
P+G +E + A+ ++V+ P ++ PC + Q +A A C ++H +F C
Sbjct: 573 PSGMIEGTPQLHANAWRVSSTCFAPVH-VPVVDPCNINQQNIGYA-AHCDVIHQELFAPC 630
Query: 771 HRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPG 829
H + +Y C C C GS CLC L+ YA C Q G +R Q + C V+C
Sbjct: 631 HIYISPGLYYQLCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQK 688
Query: 830 GQEYRECAPACGQHC---GKPEDCGELGSCVAGCNCPLGLLW-DPEGQCVPPSLCPCQLG 885
G Y C+ C C PE C + C GCNCP G + D CVP C C
Sbjct: 689 GMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYR 746
Query: 886 ARRYAPGSATMKECNRCICQERGLWNCTARHCPSQA-FCPR------------ELVYAPG 932
Y PG C C G C PS CP EL
Sbjct: 747 GSVYQPGELIPTPSGLCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 933 ACLLTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
C TC + + N +C S GCVC PG
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPG------------------------------ 835
Query: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL-FT 1049
VCR ++CT C G HY +FDGL + Y C+ L++ A +
Sbjct: 836 ------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDIS 889
Query: 1050 VSAQNLPCGASGLTCTKALAVRLEGTVVHML-RGRAVTVNGVSVTPPKVYTGPGLSLRRA 1108
V AQN C + + C+K++ + + T +++ +G + Y L +A
Sbjct: 890 VIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTY-----QLWKA 944
Query: 1109 GLFLLL-STHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
G ++++ +T+LWD T + +++ PQ++ +++GLCG+FD SND+ + +
Sbjct: 945 GYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRN 1004
Query: 1168 AELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYE 1227
A + SW L C P + PC + ++ +A+ C L +F C + +
Sbjct: 1005 ARVFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAK 1063
Query: 1228 WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
C D C C+ GGDCECLC++IA YA +C + G + WRS +CSL CE
Sbjct: 1064 NCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCE 1112
Score = 247 bits (631), Expect = 2e-64
Identities = 162/530 (30%), Positives = 239/530 (45%), Gaps = 57/530 (10%)
Query: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
P C +N C DGC CP G V+ + C+ + CPC G Y + I+
Sbjct: 345 PPTCTFEKQCLGSNLHC----LDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIE 400
Query: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVR-EASGLFT 1049
++C CVC G W+CT Q +C G H+ TFDG +++ G C+Y+LV+ FT
Sbjct: 401 QECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFT 460
Query: 1050 VSAQNLPCGAS-GLTCTKALAVRLEGTVVHMLRGRAVTV--NGVSVTPPKVYTGPGLSLR 1106
++ Q PC + GL C +++ + LE + VT+ G +T P G +L
Sbjct: 461 ITLQKAPCEQNLGLVCLQSITLILEDDF-----NKQVTLGRGGQILTSP----NQGFNLN 511
Query: 1107 -------RAGLFLLLSTHLGLTLLWD-GGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLR 1158
+ LF+LL T GL +L+ G R+ +QL+ ++ R GLCG F+G+ +D
Sbjct: 512 GIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFL 571
Query: 1159 SRQGVLEPTAELAAHSWRLSPLCPEPGDLP--HPCTMNTHRAGWARARCGALLQPLFTLC 1216
S G++E T +L A++WR+S C P +P PC +N G+A A C + Q LF C
Sbjct: 572 SPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYA-AHCDVIHQELFAPC 630
Query: 1217 HAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQ-ELCSLQC 1275
H + P +Y+ C +DAC C S CLC+A+A YA C +HG + +R+Q C++ C
Sbjct: 631 HIYISPGLYYQLCRHDACKCGS----SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC 686
Query: 1276 EGGQVYEACGPTCPPTCHE-QHPEPGWHCQVVACVEGCFCPEGTLLHG--GACLEPASCP 1332
+ G +Y C C +C PE C C EGC CPEG C+ C
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPE---QCS-DDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 1333 CEWGRNSFPPGSVLQKDCGNCTCQEGQWHC--------------GGDGGHCEELVPACAE 1378
C + + + PG ++ G C C G C G + C P
Sbjct: 743 CHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPA 802
Query: 1379 GEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHC 1428
G C+ + + C C G CA C G C+ C
Sbjct: 803 GGVNCETTCANLAMNFTCTPSSPCISGC---VCAPGVCRRGMFNCTYYPC 849
Score = 186 bits (473), Expect = 4e-46
Identities = 105/367 (28%), Positives = 179/367 (48%), Gaps = 19/367 (5%)
Query: 1007 GQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL---FTVSAQNLP-CGASGL 1062
G R G C+ G H+ TFDG+ + +PG C Y+ ++ L +TV N P C S
Sbjct: 57 GNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY 116
Query: 1063 TCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTL 1122
+C +++++ + G + NG+S+T P+ T + + + ++L+ T G +L
Sbjct: 117 SCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQ--TIGQIFIEKLADYILVKTTFGFSL 174
Query: 1123 LWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----- 1177
WDG + + ++LS +G+ GLCG+++ S+D Q + A+SW +
Sbjct: 175 AWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDD 234
Query: 1178 SPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCD 1237
+ P D P+PC+ +C LLQ F CH + P + C+ D C D
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTD 294
Query: 1238 SGGDCECLCSAIATYADECARHGHHVR-WRSQ-ELCSLQCEGGQVYEACGPTCPPTCHEQ 1295
D E C A YA C+ G+ ++ WR C+ +C+ V+ C CPPTC +
Sbjct: 295 ---DDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFE 351
Query: 1296 HPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTC 1355
G + + C++GC+CP+G ++ G C+ +CPC + ++ GS ++++C C C
Sbjct: 352 KQCLGSN---LHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECVC 408
Query: 1356 QEGQWHC 1362
G W+C
Sbjct: 409 VGGVWNC 415
Score = 94.0 bits (232), Expect = 3e-18
Identities = 145/593 (24%), Positives = 215/593 (36%), Gaps = 115/593 (19%)
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLF 1048
+Q + ++C +W C RC +TFDG Y+LVR +
Sbjct: 1424 VQVNSDICC---PEWECPC-----RCSMLSELSIITFDGNNAALYSMASYILVRIPGEII 1475
Query: 1049 TV-----SAQNLPCGASGLTCTKALAVR--LEGTVVHMLRGRAVTVNGVSVTPPKVYTGP 1101
S P G C K L V + +V+ L R V V+ + V P ++
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRL-ARKVEVDSIVVPLP--FSSQ 1532
Query: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA----GLCGDFDGDASNDL 1157
LS+ +G +++T GL + W T + + + FR ++ GLCG + D +DL
Sbjct: 1533 ELSIEDSGSMYVITTPAGLIIKWSHLTGI-IDIHFGFRFNLSSYTEGLCGICNEDPDDDL 1591
Query: 1158 RSRQGVLEPTAE---LAAHSWRLSPLC------PEPGDLPHPCTMNTHRAGWARARCGAL 1208
R + G + E L SW + P H C+ +C L
Sbjct: 1592 RMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS-----------QCIDL 1640
Query: 1209 L-QPLFTLCHAEVPPQQHYE--WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRW 1265
L + +F CH +V P+ E W Y C A++ Y C + ++W
Sbjct: 1641 LNRRIFIPCHDKVSPEDFCEKMWINYTYFW-------NYECDALSAYVALCNKFDICIQW 1693
Query: 1266 RSQELCSLQCEGGQVYEACGPTCPP-TCHEQHPEPGWHCQVVACV---EGCFCPEGTLLH 1321
R+ + CSL C G+ Y+ C C TC Q W +C+ E C C GT+LH
Sbjct: 1694 RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQ-----WFYGHTSCLNLREDCVCKVGTVLH 1748
Query: 1322 GGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGD---GGHCEELVPACAE 1378
P S C + +K+C CT E Q G+ GG + C
Sbjct: 1749 -----RPHSAQC-----------IPEKECA-CTDSEDQPRTAGEIWNGG-----IDECTL 1786
Query: 1379 GEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQ 1438
+ C ENG +P CD + + E G + CS C LC+
Sbjct: 1787 YK--CLENGSIIPIEPDCDEEPT--PVCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETS 1842
Query: 1439 -DDCGDGT-----DEPSYPCPQGLLACADGRCLPPALLCDGHPDC------LDAADEESC 1486
C + P CPQ C +C P++ P+C + EE C
Sbjct: 1843 IPTCTNSQKLIVGHSPLSCCPQYKCECDPLKC--PSI---STPECREDQFMIQVRQEEPC 1897
Query: 1487 LGQVTCVPGEVS-----CVDGTCLGAIQLCDGVWDCPD-GADEGPGHCPLPSL 1533
CV + C DG L + L + CP P CP+P L
Sbjct: 1898 CFSPFCVCESCTKPVPLCHDGEFL-TVDLNSTHFCCPQYYCVCEPNLCPMPLL 1949
Score = 79.3 bits (194), Expect = 9e-14
Identities = 35/105 (33%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLP 2941
CT +C ++ + R C CP C + + C GC CP GL + N +C+
Sbjct: 327 CTDKCDDSFVHRDCISC------CPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 2942 RSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
CPC HG Y+ G+ C C CV G CT + CPV C
Sbjct: 381 LENCPCGFHGLAYSVGSKIE-QECTECVCVGGVWNCTEQDCPVQC 424
Score = 68.2 bits (165), Expect = 2e-10
Identities = 84/351 (23%), Positives = 140/351 (39%), Gaps = 42/351 (11%)
Query: 555 CAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLIL-LEHGACD-- 611
C + CP C++ + +TFDG + + + Y LV+ + G++++ +E + +
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMAS--YILVR--IPGEIIVAHIEKCSMNQA 1487
Query: 612 -----AGSCLHAISVSLEDTHIQL-RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLL 665
+G C ++V+ I + R + V V+ V LP+ E LS+ + S +++
Sbjct: 1488 PSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVIT 1546
Query: 666 RWPGAQVLWGLSDPVAYITLDPRH--AHQVQGLCGTFTQNQQDDFLTPAGDVETS---IA 720
G + W + I R + +GLCG ++ DD G + T+ I
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606
Query: 721 AFASKFQVAGKGRCPSEDSALLSP---CTTHSQRHAFAEAACAILHSSVFQECHRLVDKE 777
F +++ S + + P CT H +L+ +F CH V E
Sbjct: 1607 LFIESWEIE-----KSFEVTMRRPVRNCTEHD-----CSQCIDLLNRRIFIPCHDKVSPE 1656
Query: 778 PFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECA 837
F C + C LSAY C + WR C + CP G+EY+ C
Sbjct: 1657 DF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPCV 1713
Query: 838 PAC-GQHCGKPEDCGELGSCV---AGCNCPLG-LLWDP-EGQCVPPSLCPC 882
C + C G SC+ C C +G +L P QC+P C C
Sbjct: 1714 RPCEARTCLNQWFYGHT-SCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 66.6 bits (161), Expect = 6e-10
Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
P +C G+N C GC+CP G+++ N C+ ++CPC G Y GS + + C
Sbjct: 345 PPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECT 404
Query: 3163 NCSCVSGLIANCSSWPC 3179
C CV G + NC+ C
Sbjct: 405 ECVCVGG-VWNCTEQDC 420
Score = 65.9 bits (159), Expect = 1e-09
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 11/87 (12%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CPP+C K + HC++GC CP GL++ + C+ L CPC + G+++ +G+
Sbjct: 344 CPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPC------GFHGLAYSVGS 397
Query: 2695 -----CSQCVCEKGELLCQPGGCPLPC 2716
C++CVC G C CP+ C
Sbjct: 398 KIEQECTECVCVGGVWNCTEQDCPVQC 424
Score = 65.9 bits (159), Expect = 1e-09
Identities = 86/355 (24%), Positives = 130/355 (36%), Gaps = 55/355 (15%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQP-----GHCQR-- 247
C+ S TFDG + +Y+L H+ P G C +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 248 -VTMGPEEVLIQ--AGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDR- 303
VT ++++ A V V +VP S LS++ G V++ G++++
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLPFS--SQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 304 TGSISISVDHE--LWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFG---NSWRLPGSE 358
TG I I L T+GLCG+ N P+DD G + G SW + S
Sbjct: 1559 TGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKS- 1617
Query: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
EV + D ++ D+ ++ + F CH +VSP ++ E
Sbjct: 1618 ------FEVTMRRPVRNCTEHDC------SQCIDLLNRRI---FIPCHDKVSPEDFCEKM 1662
Query: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDC 478
Y C ++YV C + I I+WR P +C CP G+ Y C
Sbjct: 1663 WINYTYF----------WNYECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPC 1712
Query: 479 VSLCPP-SCEAVGQGEEESC---REECVSGCECPRGLFW---NGTLCVPAAHCPC 526
V C +C SC RE+CV C G + C+P C C
Sbjct: 1713 VRPCEARTCLNQWFYGHTSCLNLREDCV----CKVGTVLHRPHSAQCIPEKECAC 1763
Score = 65.1 bits (157), Expect = 2e-09
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 14/107 (13%)
Query: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQ 4876
+C V C + CP C + + C GC CP G ++ NGTC+ CPC
Sbjct: 330 KCDDSFVHRDCISCCPPTCT-FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGF 388
Query: 4877 HSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQV 4923
H L + + G+ + + CT CVC GG ++C+ DC V
Sbjct: 389 HGLAYSV-------------GSKIEQECTECVCVGGVWNCTEQDCPV 422
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/104 (32%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD--GGCVPIG 4115
C C GM C++ C C L C DD C +GC CP+G +D CVPI
Sbjct: 682 CAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDD--CAEGCNCPEGKFYEDTLNFCVPIF 739
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTH 4159
HC C +G + PG C C G + C P H
Sbjct: 740 HCRC-HYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Score = 62.0 bits (149), Expect = 1e-08
Identities = 60/235 (25%), Positives = 78/235 (33%), Gaps = 69/235 (29%)
Query: 3529 CGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGL--CVPPAHCR 3586
C G H C C SC LS C S C C CP G+ +D L CVP HCR
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQC---SDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 3587 CQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPG 3646
C Y+ GS + +PGE++ P C C G ++C E+
Sbjct: 743 CHYR--------------GSVY------QPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Query: 3647 VWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYREC 3706
+ + DC R P P PAG
Sbjct: 783 ICPEGKEYFDC----------------RFPDP-----------------ELPAG------ 803
Query: 3707 QPGEGCPFSCAHVTQQVGCF-SEGCEEGCHCPEGTFQHRL--ACVQECPCVLTAW 3758
G C +CA++ C S C GC C G + + CP V T +
Sbjct: 804 --GVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIY 856
Score = 60.1 bits (144), Expect = 6e-08
Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 11/105 (10%)
Query: 4665 PEC--EAQDTVFTLDCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPI 4720
P C + D+ DC + CP +C QCL C GC CP G ++ +G C+ +
Sbjct: 325 PACTDKCDDSFVHRDCISCCPPTCTF---EKQCLGSNLHCLDGCYCPDGLVMDNGTCISL 381
Query: 4721 SSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPV 4765
+C CG S ++ +C C CV C Q+CPV
Sbjct: 382 ENCPCGFHGLAYS----VGSKIEQECTECVCVGGVWNCTEQDCPV 422
Score = 60.1 bits (144), Expect = 6e-08
Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 4421 DSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNC 4480
D C F C S C C Q C GCYCP GL+ G CI E C C
Sbjct: 329 DKCDDSFVHRDCISCCPPTCT--FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPC 386
Query: 4481 -WHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGC 4519
+H G+ + G +++ C EC C G +CT Q C
Sbjct: 387 GFH------GLAYSVGSKIEQECTECVCVGGVWNCTEQDC 420
Score = 60.1 bits (144), Expect = 6e-08
Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 41/310 (13%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMGP 252
A C + HY +FDG Y ++ C L +AD + + +C +
Sbjct: 851 AVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKC-----FDNDIVCS 905
Query: 253 EEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRL---------DR 303
+ VLI G+ + P Q G L+ + + G +VV DR
Sbjct: 906 KSVLISVGDTEIYLNDTPYKQK--QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963
Query: 304 TGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSES--GC 361
+I I V + + GLCG ++ +D A FG+SW L ES
Sbjct: 964 KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDET 1023
Query: 362 LDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFA 421
+ E Q P A+ C L F C + + + C
Sbjct: 1024 IKPCEAHQNKFPY---------------AKKECSILYSDIFASCRNVIDVTSFAKNCHED 1068
Query: 422 YCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSL 481
C + G + +C + A+Y C + I I WR C C + Y++ +
Sbjct: 1069 TCNCNLGGD-----CECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC---EYYNEGLGE 1120
Query: 482 CPPSCEAVGQ 491
P + GQ
Sbjct: 1121 GPYMLASYGQ 1130
Score = 57.8 bits (138), Expect = 3e-07
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 12/133 (9%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP--CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGP 2914
C++LA C G H D TQ C C + ML+ H C C++
Sbjct: 656 CNALAHYAYLC-GQHGVPIDFRTQISFCAVVCQKGMLY------HHCSSFCLHSCISLSS 708
Query: 2915 GIECTGFCAPGCTCPPGLFLHNA--SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVS 2972
+C+ CA GC CP G F + C+P C C G +Y G + S C C +
Sbjct: 709 PEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPS-GLCQCSN 767
Query: 2973 GKMACTSERCPVA 2985
G + C P A
Sbjct: 768 GTVKCDELATPSA 780
Score = 57.8 bits (138), Expect = 3e-07
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 3105 SCAELSAPRGTNQTCHPGCHCPSGMLLLN--NVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
SC LS+P + C GC+CP G + N CVP C C + G +Y PG + P
Sbjct: 702 SCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSG 761
Query: 3163 NCSCVSGLI 3171
C C +G +
Sbjct: 762 LCQCSNGTV 770
Score = 57.4 bits (137), Expect = 4e-07
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQV-CQKGCRCPKGSLEQDGGCVPIGH 4116
C C C + CP C+ ++ C + C GC CP G + +G C+ + +
Sbjct: 327 CTDKCDDSFVHRDCISCCPPTCTFEKQ---CLGSNLHCLDGCYCPDGLVMDNGTCISLEN 383
Query: 4117 CDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
C C G +++ GS+ + C C C G +CT Q CP
Sbjct: 384 CPC-GFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCP 421
Score = 55.1 bits (131), Expect = 2e-06
Identities = 47/184 (25%), Positives = 59/184 (32%), Gaps = 46/184 (25%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQD--GRCVPISSCRCGLPSANASWE 4735
C++ C HSC L QC C GC CP G+ +D CVPI CRC +
Sbjct: 695 CSSFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGS----V 749
Query: 4736 LAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPG 4795
P + + C C N ++ C P C G
Sbjct: 750 YQPGELIPTPSGLCQCSNGTVKCDELATP--------------------SAVHICPEGKE 789
Query: 4796 VAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICV-QEPCQPGCG 4854
C+ D PE P G V +C C +L C PC GC
Sbjct: 790 YFDCRFPD------------PELPAGGV------NCETTCANLAMNFTCTPSSPCISGCV 831
Query: 4855 CPGG 4858
C G
Sbjct: 832 CAPG 835
Score = 53.9 bits (128), Expect = 4e-06
Identities = 50/180 (27%), Positives = 62/180 (34%), Gaps = 38/180 (21%)
Query: 2624 ADLCQKGLVPP-----CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTR--CLPLSECP 2676
A +CQKG++ C SC+ + CS C EGC CP G DT C+P+ C
Sbjct: 683 AVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 2677 CLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVR 2736
C + PG + C C G + C P C G
Sbjct: 743 CHYRGSVYQPG-ELIPTPSGLCQCSNGTVKCDELATP------------SAVHICPEGKE 789
Query: 2737 ---ARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCL-APG 2792
RF P P GG CE T C +T T S C C+ APG
Sbjct: 790 YFDCRFPDPELPA---GGVNCE----------TTCANLAMNFT-CTPSSPCISGCVCAPG 835
Score = 52.4 bits (124), Expect = 1e-05
Identities = 36/130 (27%), Positives = 52/130 (40%), Gaps = 18/130 (13%)
Query: 3290 YCEGPRAQGEVCQALPCPVTN-------CT--AIEGAEYSPCGPPCPRSCDDLVHCVW-- 3338
YC C P+ + CT + + C CP +C C+
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSN 358
Query: 3339 -RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR 3397
C GCYCP G V+ NG C+ +C C G + G+++ + C C C+ G
Sbjct: 359 LHCLDGCYCPDGLVMD-NGT-CISLENCPCG--FHGLAYSVGSKIEQE--CTECVCVGGV 412
Query: 3398 LNCTDLPCPV 3407
NCT+ CPV
Sbjct: 413 WNCTEQDCPV 422
Score = 51.6 bits (122), Expect = 2e-05
Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 7/102 (6%)
Query: 3315 EGAEYSPCGPPCPRSCDDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLL 3371
+G Y C C SC L C C GC CP G+ CV HC C
Sbjct: 688 KGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC--HY 745
Query: 3372 TGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCP 3413
G + PG + P G C C G + C +L P CP
Sbjct: 746 RGSVYQPGELIPTPSGL--CQCSNGTVKCDELATPSAVHICP 785
Score = 51.2 bits (121), Expect = 3e-05
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 10/135 (7%)
Query: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQV 1835
C + R C+ + R P D C ++ + + + CP TC + +
Sbjct: 300 CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCI----SCCPPTC---TFEK 352
Query: 1836 TCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDG 1895
C GC+CP+G V+ + G C+ CPC G Y G +I+ +C C+C G
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGG 411
Query: 1896 RPRRCRLNPDCAVDC 1910
C DC V C
Sbjct: 412 -VWNC-TEQDCPVQC 424
Score = 51.2 bits (121), Expect = 3e-05
Identities = 47/172 (27%), Positives = 58/172 (33%), Gaps = 42/172 (24%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHN--GTCVPPTACPCT 4875
C G + C++ C C L C + C GC CP G+ + CVP C C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC- 743
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV---------------- 4919
+ PG ++ C C G C +
Sbjct: 744 ------------HYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYF 791
Query: 4920 DCQVPPGETWQQVAPGELGLCEQTC--LEMNATKTQSNCSSARASGCVCQPG 4969
DC+ P E P CE TC L MN T T S S SGCVC PG
Sbjct: 792 DCRFPDPEL-----PAGGVNCETTCANLAMNFTCTPS---SPCISGCVCAPG 835
Score = 47.4 bits (111), Expect = 4e-04
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 9/94 (9%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLL--EQAGGCIPPEECNC 4480
C +H C S C C + S + C D C GC CP+G + C+P C C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPIFHCRC 743
Query: 4481 WHTSAAGAGMTLAPGDRLQLGCKECECRRGELHC 4514
+ G PG+ + C+C G + C
Sbjct: 744 HY-----RGSVYQPGELIPTPSGLCQCSNGTVKC 772
Score = 47.0 bits (110), Expect = 5e-04
Identities = 133/558 (23%), Positives = 188/558 (33%), Gaps = 121/558 (21%)
Query: 4678 CANQCP-HSCADLW--DRVQCLQGPCRPGCRCPPGQLVQ---DGRCVPISSCRCGLP--- 4728
C C +C + W CL R C C G ++ +C+P C C
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLN--LREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQ 1769
Query: 4729 --SANASWELAPAQAVQLDC-QNCTCVNESLVCPHQECPV--------LGPWSAWSSCSA 4777
+A W + C +N + + C + PV +G W+ CS
Sbjct: 1770 PRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSK 1829
Query: 4778 P-CGGGTMERHR---TCEGGP----GVAPCQAQDTEQRQECNLQPCP-----ECPPGQVL 4824
CG T TC G +P + + EC+ CP EC Q +
Sbjct: 1830 EVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCP-QYKCECDPLKCPSISTPECREDQFM 1888
Query: 4825 SACATSCPCLCWHLQPGAICVQEPC-QPGCGCPGGQLLH---NGT--CVPPTACPCTQHS 4878
PC C+ CV E C +P C G+ L N T C P C C +
Sbjct: 1889 IQVRQEEPC-CF----SPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCCPQYYCVCEPNL 1943
Query: 4879 LPWGL-------TLTLEEQAQELPPGTVLTRNCTRCV---CHGGAFS-----------CS 4917
P L L E + + P NC V C G F+ C
Sbjct: 1944 CPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQSDCGCI 2003
Query: 4918 LVDCQVPPGETWQQVA---PGELG---LCEQTCLEMNATK-------------TQSNCSS 4958
C+ +Q+V+ PG+ L E C + + T NCS
Sbjct: 2004 QYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDNHTGFHTLNFTLVNCSK 2063
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCEC-WHLGRP----HLPGSEWQEACESCLCLS--- 5010
V P S G C + C +H+ + GS W C + C+
Sbjct: 2064 KCDVHQVYTPSP--SDYGCCGTCKNVSCKFHMENGTSVVYAVGSTWHYNCTTYECVKTDE 2121
Query: 5011 GRPVC--TQHCSPLT---CAQGEEMV-LEPGSCCPSCRREAPEEQSPSCQLLTELRNFTK 5064
G + T C P C E +V L CC C+RE CQ + K
Sbjct: 2122 GAIILNYTMVCPPFNETECKMSEGIVKLYNEGCCKICKRE-----ERICQKVIIKSVIRK 2176
Query: 5065 GTCYLDQ-VEVSYCSGYCPSST-HVMPEEPYLQSQCDCCSYRLDPESPVRILN--LRCLG 5120
C + V+ C G CPS+T + + E +L+ C CC E+ VR L+ L C G
Sbjct: 2177 QDCMSQSPINVASCDGKCPSATIYNINIESHLRF-CKCCR-----ENGVRNLSVPLYCSG 2230
Query: 5121 GHTEPVVL---PVIHSCQ 5135
TE + P+ +CQ
Sbjct: 2231 NGTEIMYTLQEPIDCTCQ 2248
Score = 46.6 bits (109), Expect = 6e-04
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQA-GPCVPEDHCECWHLGRPHLPGSE 4998
C +C+ +++ + CS A GC C G F CVP HC C + G + PG
Sbjct: 699 CLHSCISLSSPE---QCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGEL 755
Query: 4999 WQEACESCLCLSGRPVCTQHCSPLT---CAQGEE 5029
C C +G C + +P C +G+E
Sbjct: 756 IPTPSGLCQCSNGTVKCDELATPSAVHICPEGKE 789
Score = 45.8 bits (107), Expect = 0.001
Identities = 36/158 (22%), Positives = 55/158 (34%), Gaps = 37/158 (23%)
Query: 3487 CLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLH-PCGQPCPRS 3545
C + +RACS P + +++ CTD +H C CP +
Sbjct: 300 CRAATEYARACSHAGYP------------IQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347
Query: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAG 3605
C + C ++ C C CP G + +G C+ +C C + A +
Sbjct: 348 C---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSV--------- 395
Query: 3606 SRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
G + C C CV G+ C E DCP
Sbjct: 396 -----------GSKIEQECTECVCVGGVWNCTE-QDCP 421
Score = 45.4 bits (106), Expect = 0.001
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 4937 LGLCEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP 4995
+ C TC E + +C GC C G G C+ ++C C G +
Sbjct: 341 ISCCPPTCTFEKQCLGSNLHC----LDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSV 395
Query: 4996 GSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
GS+ ++ C C+C+ G CT+ P+ C+
Sbjct: 396 GSKIEQECTECVCVGGVWNCTEQDCPVQCS 425
Score = 44.7 bits (104), Expect = 0.002
Identities = 45/173 (26%), Positives = 60/173 (34%), Gaps = 44/173 (25%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA--CVQ--ECP 3752
C G LY C C SC ++ C S+ C EGC+CPEG F CV C
Sbjct: 686 CQKGMLYHHCS--SFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 3753 CVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC-------SLD 3805
C G G+ + T G C C++G + C ++
Sbjct: 743 CHYR--------------------GSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Query: 3806 DCFEADGGF-----GPWSPWG--PCSRSCGGLGTRTRSRQCVLTMPTLSGQGC 3851
C E F P P G C +C L + C + P +SG C
Sbjct: 783 ICPEGKEYFDCRFPDPELPAGGVNCETTCANL---AMNFTCTPSSPCISGCVC 832
Score = 43.9 bits (102), Expect = 0.004
Identities = 64/301 (21%), Positives = 95/301 (31%), Gaps = 80/301 (26%)
Query: 4818 CPPGQVLSACATSCP---CLCWHLQPGAICVQEPCQPGCGCPGGQLLH---NGTCVPPTA 4871
CP G+ C C CL C+ + C C G +LH + C+P
Sbjct: 1703 CPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN--LREDCVCKVGTVLHRPHSAQCIPEKE 1760
Query: 4872 CPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV----DCQVPPGE 4927
C CT + + Q G + C + + S++ DC P
Sbjct: 1761 CACT------------DSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTP 1808
Query: 4928 TWQQVAPGELGLCEQ-TCLEMNATKTQSNCSSARASGCVCQP----GHFRSQAGPCVPED 4982
++ A +G+ ++ TC + C GH C P+
Sbjct: 1809 VCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGH---SPLSCCPQY 1865
Query: 4983 HCECWHLGRPHLPGSEWQE-------------------ACESC-----LCLSGRPV---- 5014
CEC L P + E +E CESC LC G +
Sbjct: 1866 KCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDL 1925
Query: 5015 ------CTQH---CSP-------LTCAQGEEMVLE--PGSCCPS--CRREAPEEQSPSCQ 5054
C Q+ C P L CA+ +V E G CCP+ C P+C+
Sbjct: 1926 NSTHFCCPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCE 1985
Query: 5055 L 5055
+
Sbjct: 1986 V 1986
Score = 42.7 bits (99), Expect = 0.009
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 1812 CSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE-GWCVWPRQCP 1869
C +++ C+ C +C +S C D + GC CPEG+ +CV C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSDDC---AEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 1870 CLVDGARYWPGQRIKADCQLCICQDG 1895
C G+ Y PG+ I LC C +G
Sbjct: 743 CHYRGSVYQPGELIPTPSGLCQCSNG 768
Score = 42.0 bits (97), Expect = 0.016
Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 25/113 (22%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPCV 3754
C ++R+C CP +C Q +G + C +GC+CP+G C+ + CPC
Sbjct: 331 CDDSFVHRDCI--SCCPPTCTFEKQCLGS-NLHCLDGCYCPDGLVMDNGTCISLENCPC- 386
Query: 3755 LTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
G G G +++ C C C G +C+ DC
Sbjct: 387 -------------GFHGLAYSVGSKIEQ------ECTECVCVGGVWNCTEQDC 420
Score = 41.2 bits (95), Expect = 0.027
Identities = 77/323 (23%), Positives = 98/323 (30%), Gaps = 86/323 (26%)
Query: 3303 ALPCPVTNCTAIEGAEYSPCGPPC-PRSCDDL-----VHCVWRCQPGCYCPPGQVL-SSN 3355
+L CP EG EY PC PC R+C + C+ + C C G VL +
Sbjct: 1700 SLSCP-------EGKEYQPCVRPCEARTCLNQWFYGHTSCL-NLREDCVCKVGTVLHRPH 1751
Query: 3356 GAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEG------RLNCTDLPCPVPG 3409
A C+ C+C D R D C CLE +C + P PV
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPV-- 1809
Query: 3410 GWCP---------WSEWTMCSQPCRGQTRSRSRACACPTP--QHGGAPCTGEAGEAGAQH 3458
C +WT CS+ C C T + CT
Sbjct: 1810 --CEREAEVVMGIIDKWTCCSK----------EVCGCDTTLCETSIPTCTNSQKLIVGHS 1857
Query: 3459 QREACPSYATCPVDGAWGPWGPWSPC--DMCLGQSHRSRACSRPP---TPEGGRPCPGNH 3513
CP Y C D P C D + Q + C P +P P
Sbjct: 1858 PLSCCPQY-KCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVP--- 1913
Query: 3514 TQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQL 3573
C + D S H C CP+ VC+P C PL
Sbjct: 1914 ----LCHDGEFLTVDL---NSTHFC---CPQYY------CVCEPN------LCPMPLLNC 1951
Query: 3574 SQD---------GLCVPPAHCRC 3587
++D G C P HC C
Sbjct: 1952 AEDMNLVKENVSGQCCPTWHCEC 1974
Score = 36.2 bits (82), Expect = 0.87
Identities = 53/237 (22%), Positives = 72/237 (30%), Gaps = 57/237 (24%)
Query: 4055 PMPCEAGCPAGMEVVTCANRCPRR------------CSDLQEGIVCQDDQVCQKGCRCPK 4102
P C CP G E C C R C +L+E VC+ V +
Sbjct: 1696 PDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHR------ 1749
Query: 4103 GSLEQDGGCVPIGHCDCTDAQ------GHSWAPGSQHQDACNNCSC-QAGQL-----SCT 4150
C+P C CTD++ G W G D C C + G + C
Sbjct: 1750 ---PHSAQCIPEKECACTDSEDQPRTAGEIWNGGI---DECTLYKCLENGSIIPIEPDCD 1803
Query: 4151 AQP---CPPPTHCAWSHWSAWSPCSHS-CGPRGQQSRFRSSTSGSWAPECREEQ------ 4200
+P C W+ CS CG ++ + P C Q
Sbjct: 1804 EEPTPVCEREAEVVMGIIDKWTCCSKEVCG-------CDTTLCETSIPTCTNSQKLIVGH 1856
Query: 4201 SQSQPCPQPSC---PPLCLQGTRSRTLGDSW-LQGECQRCSCTPEGVICEDTECAVP 4253
S CPQ C P C + D + +Q + C +CE VP
Sbjct: 1857 SPLSCCPQYKCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVP 1913
Score = 35.4 bits (80), Expect = 1.5
Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Query: 3319 YSPCGPPCPRSCDDLVHCVWRCQP---GC--YCPPGQVLSSNGAICVQPGHC 3365
Y PC PC ++C D + P GC YCP +L CV P C
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 33.1 bits (74), Expect = 7.3
Identities = 35/148 (23%), Positives = 53/148 (35%), Gaps = 38/148 (25%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCP-RLCLTQG--PGIECTGFCAPGCTCPPGLFLH--- 2935
C+ CPE ++ + PC R CL Q C C C G LH
Sbjct: 1699 CSLSCPEGKEYQPCVR------PCEARTCLNQWFYGHTSCLNL-REDCVCKVGTVLHRPH 1751
Query: 2936 NASCLPRSQCPC-------QLHGQLYASGAMARLDSCNNCTCVSG------KMACTSERC 2982
+A C+P +C C + G+++ G +D C C+ + C E
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGG----IDECTLYKCLENGSIIPIEPDCDEEPT 1807
Query: 2983 PVACGWSPWTL-----WSLCS---CSCN 3002
PV + + W+ CS C C+
Sbjct: 1808 PVCEREAEVVMGIIDKWTCCSKEVCGCD 1835
Score = 32.7 bits (73), Expect = 9.6
Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 7/55 (12%)
Query: 3089 MCPRDKQWLDCA-------QGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVC 3136
+CP K++ DC G +C A N TC P C SG + VC
Sbjct: 783 ICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVC 837
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 463 bits (1191), Expect = e-129
Identities = 323/1129 (28%), Positives = 487/1129 (43%), Gaps = 127/1129 (11%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLA---GAADSTWAVHLTPGDRCPQPGH-CQR--- 247
C +W +H+ TFDG +Y+F G C+Y+ A G + + V + +C + C R
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSIS 123
Query: 248 -VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
EE+ I + G + Q+ + + ++ L D++++ G + D
Sbjct: 124 LFFSNQEEIRIYGHEIKKNGISLTLPQT--IGQIFIEKLADYILVKTTFGFSLAWDGISG 181
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSW--RLPGSESGCLDA 364
I + + + G++ GLCG YN DDF+ A F NSW + P L
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTP 241
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDV-CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
+ C G EA C LL+ PF CH + P Y +C+ C
Sbjct: 242 SDFPNPC----------SSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLC 291
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQLYSDCVSL 481
+ + C Y +AC+ I+ WR C C ++ DC+S
Sbjct: 292 --------KTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343
Query: 482 CPPSCEAVGQGEEESC---REECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CPP+C E+ C C+ GC CP GL + C+ +CPC + Y G
Sbjct: 344 CPPTCTF-----EKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSK 398
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
+ Q C CVC G W+C + CP +C+V GD H+ TFDGR YSF G C+Y LV+ K
Sbjct: 399 IEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIG--MCQYILVKGTGK 456
Query: 599 GQLLILLEHGACDAG---SCLHAISVSLED---THIQLRDSGAVLVN-GQDVGLPWIGAE 651
+ I L+ C+ CL +I++ LED + L G +L + Q L I
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI--- 513
Query: 652 GLSVRRASSAFLLLRWP-GAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLT 710
+ ++ SS F+LL+ G ++L+ + YI L + GLCGTF N +DDFL+
Sbjct: 514 -VEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLS 572
Query: 711 PAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQEC 770
P+G +E + A+ ++V+ P ++ PC + Q +A A C ++H +F C
Sbjct: 573 PSGMIEGTPQLHANAWRVSSTCFAPVH-VPVVDPCNINQQNIGYA-AHCDVIHQELFAPC 630
Query: 771 HRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPG 829
H + +Y C C C GS CLC L+ YA C Q G +R Q + C V+C
Sbjct: 631 HIYISPGLYYQLCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQK 688
Query: 830 GQEYRECAPACGQHC---GKPEDCGELGSCVAGCNCPLGLLW-DPEGQCVPPSLCPCQLG 885
G Y C+ C C PE C + C GCNCP G + D CVP C C
Sbjct: 689 GMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYR 746
Query: 886 ARRYAPGSATMKECNRCICQERGLWNCTARHCPSQA-FCPR------------ELVYAPG 932
Y PG C C G C PS CP EL
Sbjct: 747 GSVYQPGELIPTPSGLCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 933 ACLLTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
C TC + + N +C S GCVC PG
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPG------------------------------ 835
Query: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL-FT 1049
VCR ++CT C G HY +FDGL + Y C+ L++ A +
Sbjct: 836 ------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDIS 889
Query: 1050 VSAQNLPCGASGLTCTKALAVRLEGTVVHML-RGRAVTVNGVSVTPPKVYTGPGLSLRRA 1108
V AQN C + + C+K++ + + T +++ +G + Y L +A
Sbjct: 890 VIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTY-----QLWKA 944
Query: 1109 GLFLLL-STHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
G ++++ +T+LWD T + +++ PQ++ +++GLCG+FD SND+ + +
Sbjct: 945 GYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRN 1004
Query: 1168 AELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYE 1227
A + SW L C P + PC + ++ +A+ C L +F C + +
Sbjct: 1005 ARVFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAK 1063
Query: 1228 WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
C D C C+ GGDCECLC++IA YA +C + G + WRS +CSL CE
Sbjct: 1064 NCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCE 1112
Score = 247 bits (631), Expect = 2e-64
Identities = 162/530 (30%), Positives = 239/530 (45%), Gaps = 57/530 (10%)
Query: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
P C +N C DGC CP G V+ + C+ + CPC G Y + I+
Sbjct: 345 PPTCTFEKQCLGSNLHC----LDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIE 400
Query: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVR-EASGLFT 1049
++C CVC G W+CT Q +C G H+ TFDG +++ G C+Y+LV+ FT
Sbjct: 401 QECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFT 460
Query: 1050 VSAQNLPCGAS-GLTCTKALAVRLEGTVVHMLRGRAVTV--NGVSVTPPKVYTGPGLSLR 1106
++ Q PC + GL C +++ + LE + VT+ G +T P G +L
Sbjct: 461 ITLQKAPCEQNLGLVCLQSITLILEDDF-----NKQVTLGRGGQILTSP----NQGFNLN 511
Query: 1107 -------RAGLFLLLSTHLGLTLLWD-GGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLR 1158
+ LF+LL T GL +L+ G R+ +QL+ ++ R GLCG F+G+ +D
Sbjct: 512 GIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFL 571
Query: 1159 SRQGVLEPTAELAAHSWRLSPLCPEPGDLP--HPCTMNTHRAGWARARCGALLQPLFTLC 1216
S G++E T +L A++WR+S C P +P PC +N G+A A C + Q LF C
Sbjct: 572 SPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYA-AHCDVIHQELFAPC 630
Query: 1217 HAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQ-ELCSLQC 1275
H + P +Y+ C +DAC C S CLC+A+A YA C +HG + +R+Q C++ C
Sbjct: 631 HIYISPGLYYQLCRHDACKCGS----SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC 686
Query: 1276 EGGQVYEACGPTCPPTCHE-QHPEPGWHCQVVACVEGCFCPEGTLLHG--GACLEPASCP 1332
+ G +Y C C +C PE C C EGC CPEG C+ C
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPE---QCS-DDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 1333 CEWGRNSFPPGSVLQKDCGNCTCQEGQWHC--------------GGDGGHCEELVPACAE 1378
C + + + PG ++ G C C G C G + C P
Sbjct: 743 CHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPA 802
Query: 1379 GEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHC 1428
G C+ + + C C G CA C G C+ C
Sbjct: 803 GGVNCETTCANLAMNFTCTPSSPCISGC---VCAPGVCRRGMFNCTYYPC 849
Score = 186 bits (473), Expect = 4e-46
Identities = 105/367 (28%), Positives = 179/367 (48%), Gaps = 19/367 (5%)
Query: 1007 GQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL---FTVSAQNLP-CGASGL 1062
G R G C+ G H+ TFDG+ + +PG C Y+ ++ L +TV N P C S
Sbjct: 57 GNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY 116
Query: 1063 TCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTL 1122
+C +++++ + G + NG+S+T P+ T + + + ++L+ T G +L
Sbjct: 117 SCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQ--TIGQIFIEKLADYILVKTTFGFSL 174
Query: 1123 LWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----- 1177
WDG + + ++LS +G+ GLCG+++ S+D Q + A+SW +
Sbjct: 175 AWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDD 234
Query: 1178 SPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCD 1237
+ P D P+PC+ +C LLQ F CH + P + C+ D C D
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTD 294
Query: 1238 SGGDCECLCSAIATYADECARHGHHVR-WRSQ-ELCSLQCEGGQVYEACGPTCPPTCHEQ 1295
D E C A YA C+ G+ ++ WR C+ +C+ V+ C CPPTC +
Sbjct: 295 ---DDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFE 351
Query: 1296 HPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTC 1355
G + + C++GC+CP+G ++ G C+ +CPC + ++ GS ++++C C C
Sbjct: 352 KQCLGSN---LHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECVC 408
Query: 1356 QEGQWHC 1362
G W+C
Sbjct: 409 VGGVWNC 415
Score = 94.4 bits (233), Expect = 3e-18
Identities = 145/593 (24%), Positives = 215/593 (36%), Gaps = 115/593 (19%)
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLF 1048
+Q + ++C +W C RC +TFDG Y+LVR +
Sbjct: 1424 VQVNSDICC---PEWECPC-----RCSMLSELSIITFDGNNAALYSMASYILVRIPGEII 1475
Query: 1049 TV-----SAQNLPCGASGLTCTKALAVR--LEGTVVHMLRGRAVTVNGVSVTPPKVYTGP 1101
S P G C K L V + +V+ L R V V+ + V P ++
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRL-ARKVEVDSIVVPLP--FSSQ 1532
Query: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA----GLCGDFDGDASNDL 1157
LS+ +G +++T GL + W T + + + FR ++ GLCG + D +DL
Sbjct: 1533 ELSIEDSGSMYVITTPAGLIIKWSHLTGI-IDIHFGFRFNLSSYTEGLCGICNEDPDDDL 1591
Query: 1158 RSRQGVLEPTAE---LAAHSWRLSPLC------PEPGDLPHPCTMNTHRAGWARARCGAL 1208
R + G + E L SW + P H C+ +C L
Sbjct: 1592 RMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS-----------QCIDL 1640
Query: 1209 L-QPLFTLCHAEVPPQQHYE--WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRW 1265
L + +F CH +V P+ E W Y C A++ Y C + ++W
Sbjct: 1641 LNRRIFIPCHDKVSPEDFCEKMWINYTYFW-------NYECDALSAYVALCNKFDICIQW 1693
Query: 1266 RSQELCSLQCEGGQVYEACGPTCPP-TCHEQHPEPGWHCQVVACV---EGCFCPEGTLLH 1321
R+ + CSL C G+ Y+ C C TC Q W +C+ E C C GT+LH
Sbjct: 1694 RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQ-----WFYGHTSCLNLREDCVCKVGTILH 1748
Query: 1322 GGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGD---GGHCEELVPACAE 1378
P S C + +K+C CT E Q G+ GG + C
Sbjct: 1749 -----RPHSAQC-----------IPEKECA-CTDSEDQPRTAGEIWNGG-----IDECTL 1786
Query: 1379 GEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQ 1438
+ C ENG +P CD + + E G + CS C LC+
Sbjct: 1787 YK--CLENGSIIPIEPDCDEEPT--PVCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETS 1842
Query: 1439 -DDCGDGT-----DEPSYPCPQGLLACADGRCLPPALLCDGHPDC------LDAADEESC 1486
C + P CPQ C +C P++ P+C + EE C
Sbjct: 1843 IPTCTNSQKLIVGHSPLSCCPQYKCECDPLKC--PSI---STPECREDQFMIQVRQEEPC 1897
Query: 1487 LGQVTCVPGEVS-----CVDGTCLGAIQLCDGVWDCPD-GADEGPGHCPLPSL 1533
CV + C DG L + L + CP P CP+P L
Sbjct: 1898 CFSPFCVCESCTKPVPLCHDGEFL-TVDLNSTHFCCPQYYCVCEPNLCPMPLL 1949
Score = 79.3 bits (194), Expect = 9e-14
Identities = 35/105 (33%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLP 2941
CT +C ++ + R C CP C + + C GC CP GL + N +C+
Sbjct: 327 CTDKCDDSFVHRDCISC------CPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 2942 RSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
CPC HG Y+ G+ C C CV G CT + CPV C
Sbjct: 381 LENCPCGFHGLAYSVGSKIE-QECTECVCVGGVWNCTEQDCPVQC 424
Score = 68.6 bits (166), Expect = 2e-10
Identities = 84/351 (23%), Positives = 140/351 (39%), Gaps = 42/351 (11%)
Query: 555 CAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLIL-LEHGACD-- 611
C + CP C++ + +TFDG + + + Y LV+ + G++++ +E + +
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMAS--YILVR--IPGEIIVAHIEKCSMNQA 1487
Query: 612 -----AGSCLHAISVSLEDTHIQL-RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLL 665
+G C ++V+ I + R + V V+ V LP+ E LS+ + S +++
Sbjct: 1488 PSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVIT 1546
Query: 666 RWPGAQVLWGLSDPVAYITLDPRH--AHQVQGLCGTFTQNQQDDFLTPAGDVETS---IA 720
G + W + I R + +GLCG ++ DD G + T+ I
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606
Query: 721 AFASKFQVAGKGRCPSEDSALLSP---CTTHSQRHAFAEAACAILHSSVFQECHRLVDKE 777
F +++ S + + P CT H +L+ +F CH V E
Sbjct: 1607 LFIESWEIE-----KSFEVTMRRPVRNCTEHD-----CSQCIDLLNRRIFIPCHDKVSPE 1656
Query: 778 PFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECA 837
F C + C LSAY C + WR C + CP G+EY+ C
Sbjct: 1657 DF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPCV 1713
Query: 838 PAC-GQHCGKPEDCGELGSCV---AGCNCPLG-LLWDP-EGQCVPPSLCPC 882
C + C G SC+ C C +G +L P QC+P C C
Sbjct: 1714 RPCEARTCLNQWFYGHT-SCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 66.6 bits (161), Expect = 6e-10
Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
P +C G+N C GC+CP G+++ N C+ ++CPC G Y GS + + C
Sbjct: 345 PPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECT 404
Query: 3163 NCSCVSGLIANCSSWPC 3179
C CV G + NC+ C
Sbjct: 405 ECVCVGG-VWNCTEQDC 420
Score = 66.2 bits (160), Expect = 8e-10
Identities = 86/355 (24%), Positives = 130/355 (36%), Gaps = 55/355 (15%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQP-----GHCQR-- 247
C+ S TFDG + +Y+L H+ P G C +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 248 -VTMGPEEVLIQ--AGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDR- 303
VT ++++ A V V +VP S LS++ G V++ G++++
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLPFS--SQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 304 TGSISISVDHE--LWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFG---NSWRLPGSE 358
TG I I L T+GLCG+ N P+DD G + G SW + S
Sbjct: 1559 TGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKS- 1617
Query: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
EV + D ++ D+ ++ + F CH +VSP ++ E
Sbjct: 1618 ------FEVTMRRPVRNCTEHDC------SQCIDLLNRRI---FIPCHDKVSPEDFCEKM 1662
Query: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDC 478
Y C ++YV C + I I+WR P +C CP G+ Y C
Sbjct: 1663 WINYTYF----------WNYECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPC 1712
Query: 479 VSLCPP-SCEAVGQGEEESC---REECVSGCECPRGLFW---NGTLCVPAAHCPC 526
V C +C SC RE+CV C G + C+P C C
Sbjct: 1713 VRPCEARTCLNQWFYGHTSCLNLREDCV----CKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.9 bits (159), Expect = 1e-09
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 11/87 (12%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CPP+C K + HC++GC CP GL++ + C+ L CPC + G+++ +G+
Sbjct: 344 CPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPC------GFHGLAYSVGS 397
Query: 2695 -----CSQCVCEKGELLCQPGGCPLPC 2716
C++CVC G C CP+ C
Sbjct: 398 KIEQECTECVCVGGVWNCTEQDCPVQC 424
Score = 65.1 bits (157), Expect = 2e-09
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 14/107 (13%)
Query: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQ 4876
+C V C + CP C + + C GC CP G ++ NGTC+ CPC
Sbjct: 330 KCDDSFVHRDCISCCPPTCT-FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGF 388
Query: 4877 HSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQV 4923
H L + + G+ + + CT CVC GG ++C+ DC V
Sbjct: 389 HGLAYSV-------------GSKIEQECTECVCVGGVWNCTEQDCPV 422
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/104 (32%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD--GGCVPIG 4115
C C GM C++ C C L C DD C +GC CP+G +D CVPI
Sbjct: 682 CAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDD--CAEGCNCPEGKFYEDTLNFCVPIF 739
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTH 4159
HC C +G + PG C C G + C P H
Sbjct: 740 HCRC-HYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Score = 62.0 bits (149), Expect = 1e-08
Identities = 60/235 (25%), Positives = 78/235 (33%), Gaps = 69/235 (29%)
Query: 3529 CGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGL--CVPPAHCR 3586
C G H C C SC LS C S C C CP G+ +D L CVP HCR
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQC---SDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 3587 CQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPG 3646
C Y+ GS + +PGE++ P C C G ++C E+
Sbjct: 743 CHYR--------------GSVY------QPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Query: 3647 VWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYREC 3706
+ + DC R P P PAG
Sbjct: 783 ICPEGKEYFDC----------------RFPDP-----------------ELPAG------ 803
Query: 3707 QPGEGCPFSCAHVTQQVGCF-SEGCEEGCHCPEGTFQHRL--ACVQECPCVLTAW 3758
G C +CA++ C S C GC C G + + CP V T +
Sbjct: 804 --GVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIY 856
Score = 60.1 bits (144), Expect = 6e-08
Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 11/105 (10%)
Query: 4665 PEC--EAQDTVFTLDCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPI 4720
P C + D+ DC + CP +C QCL C GC CP G ++ +G C+ +
Sbjct: 325 PACTDKCDDSFVHRDCISCCPPTCTF---EKQCLGSNLHCLDGCYCPDGLVMDNGTCISL 381
Query: 4721 SSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPV 4765
+C CG S ++ +C C CV C Q+CPV
Sbjct: 382 ENCPCGFHGLAYS----VGSKIEQECTECVCVGGVWNCTEQDCPV 422
Score = 60.1 bits (144), Expect = 6e-08
Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 4421 DSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNC 4480
D C F C S C C Q C GCYCP GL+ G CI E C C
Sbjct: 329 DKCDDSFVHRDCISCCPPTCT--FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPC 386
Query: 4481 -WHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGC 4519
+H G+ + G +++ C EC C G +CT Q C
Sbjct: 387 GFH------GLAYSVGSKIEQECTECVCVGGVWNCTEQDC 420
Score = 60.1 bits (144), Expect = 6e-08
Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 41/310 (13%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMGP 252
A C + HY +FDG Y ++ C L +AD + + +C +
Sbjct: 851 AVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKC-----FDNDIVCS 905
Query: 253 EEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRL---------DR 303
+ VLI G+ + P Q G L+ + + G +VV DR
Sbjct: 906 KSVLISVGDTEIYLNDTPYKQK--QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963
Query: 304 TGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSES--GC 361
+I I V + + GLCG ++ +D A FG+SW L ES
Sbjct: 964 KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDET 1023
Query: 362 LDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFA 421
+ E Q P A+ C L F C + + + C
Sbjct: 1024 IKPCEAHQNKFPY---------------AKKECSILYSDIFASCRNVIDVTSFAKNCHED 1068
Query: 422 YCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSL 481
C + G + +C + A+Y C + I I WR C C + Y++ +
Sbjct: 1069 TCNCNLGGD-----CECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC---EYYNEGLGE 1120
Query: 482 CPPSCEAVGQ 491
P + GQ
Sbjct: 1121 GPYMLASYGQ 1130
Score = 57.8 bits (138), Expect = 3e-07
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 12/133 (9%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP--CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGP 2914
C++LA C G H D TQ C C + ML+ H C C++
Sbjct: 656 CNALAHYAYLC-GQHGVPIDFRTQISFCAVVCQKGMLY------HHCSSFCLHSCISLSS 708
Query: 2915 GIECTGFCAPGCTCPPGLFLHNA--SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVS 2972
+C+ CA GC CP G F + C+P C C G +Y G + S C C +
Sbjct: 709 PEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPS-GLCQCSN 767
Query: 2973 GKMACTSERCPVA 2985
G + C P A
Sbjct: 768 GTVKCDELATPSA 780
Score = 57.8 bits (138), Expect = 3e-07
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 3105 SCAELSAPRGTNQTCHPGCHCPSGMLLLN--NVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
SC LS+P + C GC+CP G + N CVP C C + G +Y PG + P
Sbjct: 702 SCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSG 761
Query: 3163 NCSCVSGLI 3171
C C +G +
Sbjct: 762 LCQCSNGTV 770
Score = 57.4 bits (137), Expect = 4e-07
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQV-CQKGCRCPKGSLEQDGGCVPIGH 4116
C C C + CP C+ ++ C + C GC CP G + +G C+ + +
Sbjct: 327 CTDKCDDSFVHRDCISCCPPTCTFEKQ---CLGSNLHCLDGCYCPDGLVMDNGTCISLEN 383
Query: 4117 CDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
C C G +++ GS+ + C C C G +CT Q CP
Sbjct: 384 CPC-GFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCP 421
Score = 55.1 bits (131), Expect = 2e-06
Identities = 47/184 (25%), Positives = 59/184 (32%), Gaps = 46/184 (25%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQD--GRCVPISSCRCGLPSANASWE 4735
C++ C HSC L QC C GC CP G+ +D CVPI CRC +
Sbjct: 695 CSSFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGS----V 749
Query: 4736 LAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPG 4795
P + + C C N ++ C P C G
Sbjct: 750 YQPGELIPTPSGLCQCSNGTVKCDELATP--------------------SAVHICPEGKE 789
Query: 4796 VAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICV-QEPCQPGCG 4854
C+ D PE P G V +C C +L C PC GC
Sbjct: 790 YFDCRFPD------------PELPAGGV------NCETTCANLAMNFTCTPSSPCISGCV 831
Query: 4855 CPGG 4858
C G
Sbjct: 832 CAPG 835
Score = 53.9 bits (128), Expect = 4e-06
Identities = 50/180 (27%), Positives = 62/180 (34%), Gaps = 38/180 (21%)
Query: 2624 ADLCQKGLVPP-----CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTR--CLPLSECP 2676
A +CQKG++ C SC+ + CS C EGC CP G DT C+P+ C
Sbjct: 683 AVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 2677 CLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVR 2736
C + PG + C C G + C P C G
Sbjct: 743 CHYRGSVYQPG-ELIPTPSGLCQCSNGTVKCDELATP------------SAVHICPEGKE 789
Query: 2737 ---ARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCL-APG 2792
RF P P GG CE T C +T T S C C+ APG
Sbjct: 790 YFDCRFPDPELPA---GGVNCE----------TTCANLAMNFT-CTPSSPCISGCVCAPG 835
Score = 52.4 bits (124), Expect = 1e-05
Identities = 36/130 (27%), Positives = 52/130 (40%), Gaps = 18/130 (13%)
Query: 3290 YCEGPRAQGEVCQALPCPVTN-------CT--AIEGAEYSPCGPPCPRSCDDLVHCVW-- 3338
YC C P+ + CT + + C CP +C C+
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSN 358
Query: 3339 -RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR 3397
C GCYCP G V+ NG C+ +C C G + G+++ + C C C+ G
Sbjct: 359 LHCLDGCYCPDGLVMD-NGT-CISLENCPCG--FHGLAYSVGSKIEQE--CTECVCVGGV 412
Query: 3398 LNCTDLPCPV 3407
NCT+ CPV
Sbjct: 413 WNCTEQDCPV 422
Score = 51.6 bits (122), Expect = 2e-05
Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 7/102 (6%)
Query: 3315 EGAEYSPCGPPCPRSCDDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLL 3371
+G Y C C SC L C C GC CP G+ CV HC C
Sbjct: 688 KGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC--HY 745
Query: 3372 TGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCP 3413
G + PG + P G C C G + C +L P CP
Sbjct: 746 RGSVYQPGELIPTPSGL--CQCSNGTVKCDELATPSAVHICP 785
Score = 51.2 bits (121), Expect = 3e-05
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 10/135 (7%)
Query: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQV 1835
C + R C+ + R P D C ++ + + + CP TC + +
Sbjct: 300 CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCI----SCCPPTC---TFEK 352
Query: 1836 TCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDG 1895
C GC+CP+G V+ + G C+ CPC G Y G +I+ +C C+C G
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGG 411
Query: 1896 RPRRCRLNPDCAVDC 1910
C DC V C
Sbjct: 412 -VWNC-TEQDCPVQC 424
Score = 51.2 bits (121), Expect = 3e-05
Identities = 47/172 (27%), Positives = 58/172 (33%), Gaps = 42/172 (24%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHN--GTCVPPTACPCT 4875
C G + C++ C C L C + C GC CP G+ + CVP C C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC- 743
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV---------------- 4919
+ PG ++ C C G C +
Sbjct: 744 ------------HYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYF 791
Query: 4920 DCQVPPGETWQQVAPGELGLCEQTC--LEMNATKTQSNCSSARASGCVCQPG 4969
DC+ P E P CE TC L MN T T S S SGCVC PG
Sbjct: 792 DCRFPDPEL-----PAGGVNCETTCANLAMNFTCTPS---SPCISGCVCAPG 835
Score = 47.4 bits (111), Expect = 4e-04
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 9/94 (9%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLL--EQAGGCIPPEECNC 4480
C +H C S C C + S + C D C GC CP+G + C+P C C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPIFHCRC 743
Query: 4481 WHTSAAGAGMTLAPGDRLQLGCKECECRRGELHC 4514
+ G PG+ + C+C G + C
Sbjct: 744 HY-----RGSVYQPGELIPTPSGLCQCSNGTVKC 772
Score = 47.4 bits (111), Expect = 4e-04
Identities = 133/558 (23%), Positives = 188/558 (33%), Gaps = 121/558 (21%)
Query: 4678 CANQCP-HSCADLW--DRVQCLQGPCRPGCRCPPGQLVQ---DGRCVPISSCRCGLP--- 4728
C C +C + W CL R C C G ++ +C+P C C
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLN--LREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQ 1769
Query: 4729 --SANASWELAPAQAVQLDC-QNCTCVNESLVCPHQECPV--------LGPWSAWSSCSA 4777
+A W + C +N + + C + PV +G W+ CS
Sbjct: 1770 PRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSK 1829
Query: 4778 P-CGGGTMERHR---TCEGGP----GVAPCQAQDTEQRQECNLQPCP-----ECPPGQVL 4824
CG T TC G +P + + EC+ CP EC Q +
Sbjct: 1830 EVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCP-QYKCECDPLKCPSISTPECREDQFM 1888
Query: 4825 SACATSCPCLCWHLQPGAICVQEPC-QPGCGCPGGQLLH---NGT--CVPPTACPCTQHS 4878
PC C+ CV E C +P C G+ L N T C P C C +
Sbjct: 1889 IQVRQEEPC-CF----SPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCCPQYYCVCEPNL 1943
Query: 4879 LPWGL-------TLTLEEQAQELPPGTVLTRNCTRCV---CHGGAFS-----------CS 4917
P L L E + + P NC V C G F+ C
Sbjct: 1944 CPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQSDCGCI 2003
Query: 4918 LVDCQVPPGETWQQVA---PGELG---LCEQTCLEMNATK-------------TQSNCSS 4958
C+ +Q+V+ PG+ L E C + + T NCS
Sbjct: 2004 QYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDNHTGFHTLNFTLVNCSK 2063
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCEC-WHLGRP----HLPGSEWQEACESCLCLS--- 5010
V P S G C + C +H+ + GS W C + C+
Sbjct: 2064 KCDVHQVYTPSP--SDYGCCGTCKNVSCKFHMENGTSVVYAVGSTWHYNCTTYECVKTDE 2121
Query: 5011 GRPVC--TQHCSPLT---CAQGEEMV-LEPGSCCPSCRREAPEEQSPSCQLLTELRNFTK 5064
G + T C P C E +V L CC C+RE CQ + K
Sbjct: 2122 GAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKRE-----ERICQKVIIKSVIRK 2176
Query: 5065 GTCYLDQ-VEVSYCSGYCPSST-HVMPEEPYLQSQCDCCSYRLDPESPVRILN--LRCLG 5120
C + V+ C G CPS+T + + E +L+ C CC E+ VR L+ L C G
Sbjct: 2177 QDCMSQSPINVASCDGKCPSATIYNINIESHLRF-CKCCR-----ENGVRNLSVPLYCSG 2230
Query: 5121 GHTEPVVL---PVIHSCQ 5135
TE + P+ +CQ
Sbjct: 2231 NGTEIMYTLQEPIDCTCQ 2248
Score = 46.6 bits (109), Expect = 6e-04
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQA-GPCVPEDHCECWHLGRPHLPGSE 4998
C +C+ +++ + CS A GC C G F CVP HC C + G + PG
Sbjct: 699 CLHSCISLSSPE---QCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGEL 755
Query: 4999 WQEACESCLCLSGRPVCTQHCSPLT---CAQGEE 5029
C C +G C + +P C +G+E
Sbjct: 756 IPTPSGLCQCSNGTVKCDELATPSAVHICPEGKE 789
Score = 45.8 bits (107), Expect = 0.001
Identities = 36/158 (22%), Positives = 55/158 (34%), Gaps = 37/158 (23%)
Query: 3487 CLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLH-PCGQPCPRS 3545
C + +RACS P + +++ CTD +H C CP +
Sbjct: 300 CRAATEYARACSHAGYP------------IQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347
Query: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAG 3605
C + C ++ C C CP G + +G C+ +C C + A +
Sbjct: 348 C---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSV--------- 395
Query: 3606 SRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
G + C C CV G+ C E DCP
Sbjct: 396 -----------GSKIEQECTECVCVGGVWNCTE-QDCP 421
Score = 45.4 bits (106), Expect = 0.001
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 4937 LGLCEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP 4995
+ C TC E + +C GC C G G C+ ++C C G +
Sbjct: 341 ISCCPPTCTFEKQCLGSNLHC----LDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSV 395
Query: 4996 GSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
GS+ ++ C C+C+ G CT+ P+ C+
Sbjct: 396 GSKIEQECTECVCVGGVWNCTEQDCPVQCS 425
Score = 44.7 bits (104), Expect = 0.002
Identities = 45/173 (26%), Positives = 60/173 (34%), Gaps = 44/173 (25%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA--CVQ--ECP 3752
C G LY C C SC ++ C S+ C EGC+CPEG F CV C
Sbjct: 686 CQKGMLYHHCS--SFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 3753 CVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC-------SLD 3805
C G G+ + T G C C++G + C ++
Sbjct: 743 CHYR--------------------GSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Query: 3806 DCFEADGGF-----GPWSPWG--PCSRSCGGLGTRTRSRQCVLTMPTLSGQGC 3851
C E F P P G C +C L + C + P +SG C
Sbjct: 783 ICPEGKEYFDCRFPDPELPAGGVNCETTCANL---AMNFTCTPSSPCISGCVC 832
Score = 44.3 bits (103), Expect = 0.003
Identities = 64/301 (21%), Positives = 95/301 (31%), Gaps = 80/301 (26%)
Query: 4818 CPPGQVLSACATSCP---CLCWHLQPGAICVQEPCQPGCGCPGGQLLH---NGTCVPPTA 4871
CP G+ C C CL C+ + C C G +LH + C+P
Sbjct: 1703 CPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN--LREDCVCKVGTILHRPHSAQCIPEKE 1760
Query: 4872 CPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV----DCQVPPGE 4927
C CT + + Q G + C + + S++ DC P
Sbjct: 1761 CACT------------DSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTP 1808
Query: 4928 TWQQVAPGELGLCEQ-TCLEMNATKTQSNCSSARASGCVCQP----GHFRSQAGPCVPED 4982
++ A +G+ ++ TC + C GH C P+
Sbjct: 1809 VCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGH---SPLSCCPQY 1865
Query: 4983 HCECWHLGRPHLPGSEWQE-------------------ACESC-----LCLSGRPV---- 5014
CEC L P + E +E CESC LC G +
Sbjct: 1866 KCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDL 1925
Query: 5015 ------CTQH---CSP-------LTCAQGEEMVLE--PGSCCPS--CRREAPEEQSPSCQ 5054
C Q+ C P L CA+ +V E G CCP+ C P+C+
Sbjct: 1926 NSTHFCCPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCE 1985
Query: 5055 L 5055
+
Sbjct: 1986 V 1986
Score = 42.7 bits (99), Expect = 0.009
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 1812 CSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE-GWCVWPRQCP 1869
C +++ C+ C +C +S C D + GC CPEG+ +CV C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSDDC---AEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 1870 CLVDGARYWPGQRIKADCQLCICQDG 1895
C G+ Y PG+ I LC C +G
Sbjct: 743 CHYRGSVYQPGELIPTPSGLCQCSNG 768
Score = 42.0 bits (97), Expect = 0.016
Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 25/113 (22%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPCV 3754
C ++R+C CP +C Q +G + C +GC+CP+G C+ + CPC
Sbjct: 331 CDDSFVHRDCI--SCCPPTCTFEKQCLGS-NLHCLDGCYCPDGLVMDNGTCISLENCPC- 386
Query: 3755 LTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
G G G +++ C C C G +C+ DC
Sbjct: 387 -------------GFHGLAYSVGSKIEQ------ECTECVCVGGVWNCTEQDC 420
Score = 40.8 bits (94), Expect = 0.035
Identities = 76/323 (23%), Positives = 98/323 (30%), Gaps = 86/323 (26%)
Query: 3303 ALPCPVTNCTAIEGAEYSPCGPPC-PRSCDDL-----VHCVWRCQPGCYCPPGQVL-SSN 3355
+L CP EG EY PC PC R+C + C+ + C C G +L +
Sbjct: 1700 SLSCP-------EGKEYQPCVRPCEARTCLNQWFYGHTSCL-NLREDCVCKVGTILHRPH 1751
Query: 3356 GAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEG------RLNCTDLPCPVPG 3409
A C+ C+C D R D C CLE +C + P PV
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPV-- 1809
Query: 3410 GWCP---------WSEWTMCSQPCRGQTRSRSRACACPTP--QHGGAPCTGEAGEAGAQH 3458
C +WT CS+ C C T + CT
Sbjct: 1810 --CEREAEVVMGIIDKWTCCSK----------EVCGCDTTLCETSIPTCTNSQKLIVGHS 1857
Query: 3459 QREACPSYATCPVDGAWGPWGPWSPC--DMCLGQSHRSRACSRPP---TPEGGRPCPGNH 3513
CP Y C D P C D + Q + C P +P P
Sbjct: 1858 PLSCCPQY-KCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVP--- 1913
Query: 3514 TQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQL 3573
C + D S H C CP+ VC+P C PL
Sbjct: 1914 ----LCHDGEFLTVDL---NSTHFC---CPQYY------CVCEPN------LCPMPLLNC 1951
Query: 3574 SQD---------GLCVPPAHCRC 3587
++D G C P HC C
Sbjct: 1952 AEDMNLVKENVSGQCCPTWHCEC 1974
Score = 35.8 bits (81), Expect = 1.1
Identities = 52/237 (21%), Positives = 72/237 (30%), Gaps = 57/237 (24%)
Query: 4055 PMPCEAGCPAGMEVVTCANRCPRR------------CSDLQEGIVCQDDQVCQKGCRCPK 4102
P C CP G E C C R C +L+E VC+ + +
Sbjct: 1696 PDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHR------ 1749
Query: 4103 GSLEQDGGCVPIGHCDCTDAQ------GHSWAPGSQHQDACNNCSC-QAGQL-----SCT 4150
C+P C CTD++ G W G D C C + G + C
Sbjct: 1750 ---PHSAQCIPEKECACTDSEDQPRTAGEIWNGGI---DECTLYKCLENGSIIPIEPDCD 1803
Query: 4151 AQP---CPPPTHCAWSHWSAWSPCSHS-CGPRGQQSRFRSSTSGSWAPECREEQ------ 4200
+P C W+ CS CG ++ + P C Q
Sbjct: 1804 EEPTPVCEREAEVVMGIIDKWTCCSKEVCG-------CDTTLCETSIPTCTNSQKLIVGH 1856
Query: 4201 SQSQPCPQPSC---PPLCLQGTRSRTLGDSW-LQGECQRCSCTPEGVICEDTECAVP 4253
S CPQ C P C + D + +Q + C +CE VP
Sbjct: 1857 SPLSCCPQYKCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVP 1913
Score = 35.4 bits (80), Expect = 1.5
Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Query: 3319 YSPCGPPCPRSCDDLVHCVWRCQP---GC--YCPPGQVLSSNGAICVQPGHC 3365
Y PC PC ++C D + P GC YCP +L CV P C
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 33.5 bits (75), Expect = 5.6
Identities = 35/148 (23%), Positives = 53/148 (35%), Gaps = 38/148 (25%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCP-RLCLTQG--PGIECTGFCAPGCTCPPGLFLH--- 2935
C+ CPE ++ + PC R CL Q C C C G LH
Sbjct: 1699 CSLSCPEGKEYQPCVR------PCEARTCLNQWFYGHTSCLNL-REDCVCKVGTILHRPH 1751
Query: 2936 NASCLPRSQCPC-------QLHGQLYASGAMARLDSCNNCTCVSG------KMACTSERC 2982
+A C+P +C C + G+++ G +D C C+ + C E
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGG----IDECTLYKCLENGSIIPIEPDCDEEPT 1807
Query: 2983 PVACGWSPWTL-----WSLCS---CSCN 3002
PV + + W+ CS C C+
Sbjct: 1808 PVCEREAEVVMGIIDKWTCCSKEVCGCD 1835
Score = 32.7 bits (73), Expect = 9.6
Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 7/55 (12%)
Query: 3089 MCPRDKQWLDCA-------QGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVC 3136
+CP K++ DC G +C A N TC P C SG + VC
Sbjct: 783 ICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVC 837
Score = 32.7 bits (73), Expect = 9.6
Identities = 33/129 (25%), Positives = 47/129 (36%), Gaps = 31/129 (24%)
Query: 2614 DCELGRVYVSA----DLCQKGLVPP-----CPPS-----CLDPKANRSCS-----GH--C 2652
+C+ YV+ D+C + P CP C+ P R+C GH C
Sbjct: 1673 ECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 2653 V---EGCRCPPGLLLH---DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELL 2706
+ E C C G +LH +C+P EC C E+ G +C K
Sbjct: 1733 LNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYK---- 1788
Query: 2707 CQPGGCPLP 2715
C G +P
Sbjct: 1789 CLENGSIIP 1797
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 463 bits (1191), Expect = e-129
Identities = 323/1129 (28%), Positives = 487/1129 (43%), Gaps = 127/1129 (11%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLA---GAADSTWAVHLTPGDRCPQPGH-CQR--- 247
C +W +H+ TFDG +Y+F G C+Y+ A G + + V + +C + C R
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSIS 123
Query: 248 -VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
EE+ I + G + Q+ + + ++ L D++++ G + D
Sbjct: 124 LFFSNQEEIRIYGHEIKKNGISLTLPQT--IGQIFIEKLADYILVKTTFGFSLAWDGISG 181
Query: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSW--RLPGSESGCLDA 364
I + + + G++ GLCG YN DDF+ A F NSW + P L
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTP 241
Query: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDV-CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
+ C G EA C LL+ PF CH + P Y +C+ C
Sbjct: 242 SDFPNPC----------SSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLC 291
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQLYSDCVSL 481
+ + C Y +AC+ I+ WR C C ++ DC+S
Sbjct: 292 --------KTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343
Query: 482 CPPSCEAVGQGEEESC---REECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
CPP+C E+ C C+ GC CP GL + C+ +CPC + Y G
Sbjct: 344 CPPTCTF-----EKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSK 398
Query: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
+ Q C CVC G W+C + CP +C+V GD H+ TFDGR YSF G C+Y LV+ K
Sbjct: 399 IEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIG--MCQYILVKGTGK 456
Query: 599 GQLLILLEHGACDAG---SCLHAISVSLED---THIQLRDSGAVLVN-GQDVGLPWIGAE 651
+ I L+ C+ CL +I++ LED + L G +L + Q L I
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI--- 513
Query: 652 GLSVRRASSAFLLLRWP-GAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLT 710
+ ++ SS F+LL+ G ++L+ + YI L + GLCGTF N +DDFL+
Sbjct: 514 -VEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLS 572
Query: 711 PAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQEC 770
P+G +E + A+ ++V+ P ++ PC + Q +A A C ++H +F C
Sbjct: 573 PSGMIEGTPQLHANAWRVSSTCFAPVH-VPVVDPCNINQQNIGYA-AHCDVIHQELFAPC 630
Query: 771 HRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPG 829
H + +Y C C C GS CLC L+ YA C Q G +R Q + C V+C
Sbjct: 631 HIYISPGLYYQLCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQK 688
Query: 830 GQEYRECAPACGQHC---GKPEDCGELGSCVAGCNCPLGLLW-DPEGQCVPPSLCPCQLG 885
G Y C+ C C PE C + C GCNCP G + D CVP C C
Sbjct: 689 GMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYR 746
Query: 886 ARRYAPGSATMKECNRCICQERGLWNCTARHCPSQA-FCPR------------ELVYAPG 932
Y PG C C G C PS CP EL
Sbjct: 747 GSVYQPGELIPTPSGLCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 933 ACLLTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
C TC + + N +C S GCVC PG
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPG------------------------------ 835
Query: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL-FT 1049
VCR ++CT C G HY +FDGL + Y C+ L++ A +
Sbjct: 836 ------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDIS 889
Query: 1050 VSAQNLPCGASGLTCTKALAVRLEGTVVHML-RGRAVTVNGVSVTPPKVYTGPGLSLRRA 1108
V AQN C + + C+K++ + + T +++ +G + Y L +A
Sbjct: 890 VIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTY-----QLWKA 944
Query: 1109 GLFLLL-STHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
G ++++ +T+LWD T + +++ PQ++ +++GLCG+FD SND+ + +
Sbjct: 945 GYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRN 1004
Query: 1168 AELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYE 1227
A + SW L C P + PC + ++ +A+ C L +F C + +
Sbjct: 1005 ARVFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAK 1063
Query: 1228 WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
C D C C+ GGDCECLC++IA YA +C + G + WRS +CSL CE
Sbjct: 1064 NCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCE 1112
Score = 247 bits (631), Expect = 2e-64
Identities = 162/530 (30%), Positives = 239/530 (45%), Gaps = 57/530 (10%)
Query: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
P C +N C DGC CP G V+ + C+ + CPC G Y + I+
Sbjct: 345 PPTCTFEKQCLGSNLHC----LDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIE 400
Query: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVR-EASGLFT 1049
++C CVC G W+CT Q +C G H+ TFDG +++ G C+Y+LV+ FT
Sbjct: 401 QECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFT 460
Query: 1050 VSAQNLPCGAS-GLTCTKALAVRLEGTVVHMLRGRAVTV--NGVSVTPPKVYTGPGLSLR 1106
++ Q PC + GL C +++ + LE + VT+ G +T P G +L
Sbjct: 461 ITLQKAPCEQNLGLVCLQSITLILEDDF-----NKQVTLGRGGQILTSP----NQGFNLN 511
Query: 1107 -------RAGLFLLLSTHLGLTLLWD-GGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLR 1158
+ LF+LL T GL +L+ G R+ +QL+ ++ R GLCG F+G+ +D
Sbjct: 512 GIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFL 571
Query: 1159 SRQGVLEPTAELAAHSWRLSPLCPEPGDLP--HPCTMNTHRAGWARARCGALLQPLFTLC 1216
S G++E T +L A++WR+S C P +P PC +N G+A A C + Q LF C
Sbjct: 572 SPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYA-AHCDVIHQELFAPC 630
Query: 1217 HAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQ-ELCSLQC 1275
H + P +Y+ C +DAC C S CLC+A+A YA C +HG + +R+Q C++ C
Sbjct: 631 HIYISPGLYYQLCRHDACKCGS----SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC 686
Query: 1276 EGGQVYEACGPTCPPTCHE-QHPEPGWHCQVVACVEGCFCPEGTLLHG--GACLEPASCP 1332
+ G +Y C C +C PE C C EGC CPEG C+ C
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPE---QCS-DDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 1333 CEWGRNSFPPGSVLQKDCGNCTCQEGQWHC--------------GGDGGHCEELVPACAE 1378
C + + + PG ++ G C C G C G + C P
Sbjct: 743 CHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPA 802
Query: 1379 GEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHC 1428
G C+ + + C C G CA C G C+ C
Sbjct: 803 GGVNCETTCANLAMNFTCTPSSPCISGC---VCAPGVCRRGMFNCTYYPC 849
Score = 186 bits (473), Expect = 4e-46
Identities = 105/367 (28%), Positives = 179/367 (48%), Gaps = 19/367 (5%)
Query: 1007 GQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL---FTVSAQNLP-CGASGL 1062
G R G C+ G H+ TFDG+ + +PG C Y+ ++ L +TV N P C S
Sbjct: 57 GNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY 116
Query: 1063 TCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTL 1122
+C +++++ + G + NG+S+T P+ T + + + ++L+ T G +L
Sbjct: 117 SCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQ--TIGQIFIEKLADYILVKTTFGFSL 174
Query: 1123 LWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----- 1177
WDG + + ++LS +G+ GLCG+++ S+D Q + A+SW +
Sbjct: 175 AWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDD 234
Query: 1178 SPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCD 1237
+ P D P+PC+ +C LLQ F CH + P + C+ D C D
Sbjct: 235 TKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTD 294
Query: 1238 SGGDCECLCSAIATYADECARHGHHVR-WRSQ-ELCSLQCEGGQVYEACGPTCPPTCHEQ 1295
D E C A YA C+ G+ ++ WR C+ +C+ V+ C CPPTC +
Sbjct: 295 ---DDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFE 351
Query: 1296 HPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTC 1355
G + + C++GC+CP+G ++ G C+ +CPC + ++ GS ++++C C C
Sbjct: 352 KQCLGSN---LHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECVC 408
Query: 1356 QEGQWHC 1362
G W+C
Sbjct: 409 VGGVWNC 415
Score = 94.4 bits (233), Expect = 3e-18
Identities = 145/593 (24%), Positives = 215/593 (36%), Gaps = 115/593 (19%)
Query: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLF 1048
+Q + ++C +W C RC +TFDG Y+LVR +
Sbjct: 1424 VQVNSDICC---PEWECPC-----RCSMLSELSIITFDGNNAALYSMASYILVRIPGEII 1475
Query: 1049 TV-----SAQNLPCGASGLTCTKALAVR--LEGTVVHMLRGRAVTVNGVSVTPPKVYTGP 1101
S P G C K L V + +V+ L R V V+ + V P ++
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRL-ARKVEVDSIVVPLP--FSSQ 1532
Query: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA----GLCGDFDGDASNDL 1157
LS+ +G +++T GL + W T + + + FR ++ GLCG + D +DL
Sbjct: 1533 ELSIEDSGSMYVITTPAGLIIKWSHLTGI-IDIHFGFRFNLSSYTEGLCGICNEDPDDDL 1591
Query: 1158 RSRQGVLEPTAE---LAAHSWRLSPLC------PEPGDLPHPCTMNTHRAGWARARCGAL 1208
R + G + E L SW + P H C+ +C L
Sbjct: 1592 RMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS-----------QCIDL 1640
Query: 1209 L-QPLFTLCHAEVPPQQHYE--WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRW 1265
L + +F CH +V P+ E W Y C A++ Y C + ++W
Sbjct: 1641 LNRRIFIPCHDKVSPEDFCEKMWINYTYFW-------NYECDALSAYVALCNKFDICIQW 1693
Query: 1266 RSQELCSLQCEGGQVYEACGPTCPP-TCHEQHPEPGWHCQVVACV---EGCFCPEGTLLH 1321
R+ + CSL C G+ Y+ C C TC Q W +C+ E C C GT+LH
Sbjct: 1694 RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQ-----WFYGHTSCLNLREDCVCKVGTILH 1748
Query: 1322 GGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGD---GGHCEELVPACAE 1378
P S C + +K+C CT E Q G+ GG + C
Sbjct: 1749 -----RPHSAQC-----------IPEKECA-CTDSEDQPRTAGEIWNGG-----IDECTL 1786
Query: 1379 GEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQ 1438
+ C ENG +P CD + + E G + CS C LC+
Sbjct: 1787 YK--CLENGSIIPIEPDCDEEPT--PVCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETS 1842
Query: 1439 -DDCGDGT-----DEPSYPCPQGLLACADGRCLPPALLCDGHPDC------LDAADEESC 1486
C + P CPQ C +C P++ P+C + EE C
Sbjct: 1843 IPTCTNSQKLIVGHSPLSCCPQYKCECDPLKC--PSI---STPECREDQFMIQVRQEEPC 1897
Query: 1487 LGQVTCVPGEVS-----CVDGTCLGAIQLCDGVWDCPD-GADEGPGHCPLPSL 1533
CV + C DG L + L + CP P CP+P L
Sbjct: 1898 CFSPFCVCESCTKPVPLCHDGEFL-TVDLNSTHFCCPQYYCVCEPNLCPMPLL 1949
Score = 79.3 bits (194), Expect = 9e-14
Identities = 35/105 (33%), Positives = 47/105 (44%), Gaps = 7/105 (6%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLP 2941
CT +C ++ + R C CP C + + C GC CP GL + N +C+
Sbjct: 327 CTDKCDDSFVHRDCISC------CPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 2942 RSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVAC 2986
CPC HG Y+ G+ C C CV G CT + CPV C
Sbjct: 381 LENCPCGFHGLAYSVGSKIE-QECTECVCVGGVWNCTEQDCPVQC 424
Score = 68.6 bits (166), Expect = 2e-10
Identities = 84/351 (23%), Positives = 140/351 (39%), Gaps = 42/351 (11%)
Query: 555 CAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLIL-LEHGACD-- 611
C + CP C++ + +TFDG + + + Y LV+ + G++++ +E + +
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMAS--YILVR--IPGEIIVAHIEKCSMNQA 1487
Query: 612 -----AGSCLHAISVSLEDTHIQL-RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLL 665
+G C ++V+ I + R + V V+ V LP+ E LS+ + S +++
Sbjct: 1488 PSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVIT 1546
Query: 666 RWPGAQVLWGLSDPVAYITLDPRH--AHQVQGLCGTFTQNQQDDFLTPAGDVETS---IA 720
G + W + I R + +GLCG ++ DD G + T+ I
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606
Query: 721 AFASKFQVAGKGRCPSEDSALLSP---CTTHSQRHAFAEAACAILHSSVFQECHRLVDKE 777
F +++ S + + P CT H +L+ +F CH V E
Sbjct: 1607 LFIESWEIE-----KSFEVTMRRPVRNCTEHD-----CSQCIDLLNRRIFIPCHDKVSPE 1656
Query: 778 PFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECA 837
F C + C LSAY C + WR C + CP G+EY+ C
Sbjct: 1657 DF---CEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPCV 1713
Query: 838 PAC-GQHCGKPEDCGELGSCV---AGCNCPLG-LLWDP-EGQCVPPSLCPC 882
C + C G SC+ C C +G +L P QC+P C C
Sbjct: 1714 RPCEARTCLNQWFYGHT-SCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 66.6 bits (161), Expect = 6e-10
Identities = 27/77 (35%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
P +C G+N C GC+CP G+++ N C+ ++CPC G Y GS + + C
Sbjct: 345 PPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECT 404
Query: 3163 NCSCVSGLIANCSSWPC 3179
C CV G + NC+ C
Sbjct: 405 ECVCVGG-VWNCTEQDC 420
Score = 66.2 bits (160), Expect = 8e-10
Identities = 86/355 (24%), Positives = 130/355 (36%), Gaps = 55/355 (15%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQP-----GHCQR-- 247
C+ S TFDG + +Y+L H+ P G C +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 248 -VTMGPEEVLIQ--AGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDR- 303
VT ++++ A V V +VP S LS++ G V++ G++++
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLPFS--SQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 304 TGSISISVDHE--LWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFG---NSWRLPGSE 358
TG I I L T+GLCG+ N P+DD G + G SW + S
Sbjct: 1559 TGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKS- 1617
Query: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
EV + D ++ D+ ++ + F CH +VSP ++ E
Sbjct: 1618 ------FEVTMRRPVRNCTEHDC------SQCIDLLNRRI---FIPCHDKVSPEDFCEKM 1662
Query: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDC 478
Y C ++YV C + I I+WR P +C CP G+ Y C
Sbjct: 1663 WINYTYF----------WNYECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPC 1712
Query: 479 VSLCPP-SCEAVGQGEEESC---REECVSGCECPRGLFW---NGTLCVPAAHCPC 526
V C +C SC RE+CV C G + C+P C C
Sbjct: 1713 VRPCEARTCLNQWFYGHTSCLNLREDCV----CKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.9 bits (159), Expect = 1e-09
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 11/87 (12%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CPP+C K + HC++GC CP GL++ + C+ L CPC + G+++ +G+
Sbjct: 344 CPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPC------GFHGLAYSVGS 397
Query: 2695 -----CSQCVCEKGELLCQPGGCPLPC 2716
C++CVC G C CP+ C
Sbjct: 398 KIEQECTECVCVGGVWNCTEQDCPVQC 424
Score = 65.1 bits (157), Expect = 2e-09
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 14/107 (13%)
Query: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQ 4876
+C V C + CP C + + C GC CP G ++ NGTC+ CPC
Sbjct: 330 KCDDSFVHRDCISCCPPTCT-FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGF 388
Query: 4877 HSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQV 4923
H L + + G+ + + CT CVC GG ++C+ DC V
Sbjct: 389 HGLAYSV-------------GSKIEQECTECVCVGGVWNCTEQDCPV 422
Score = 62.4 bits (150), Expect = 1e-08
Identities = 34/104 (32%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD--GGCVPIG 4115
C C GM C++ C C L C DD C +GC CP+G +D CVPI
Sbjct: 682 CAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDD--CAEGCNCPEGKFYEDTLNFCVPIF 739
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTH 4159
HC C +G + PG C C G + C P H
Sbjct: 740 HCRC-HYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Score = 62.0 bits (149), Expect = 1e-08
Identities = 60/235 (25%), Positives = 78/235 (33%), Gaps = 69/235 (29%)
Query: 3529 CGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGL--CVPPAHCR 3586
C G H C C SC LS C S C C CP G+ +D L CVP HCR
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQC---SDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 3587 CQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPG 3646
C Y+ GS + +PGE++ P C C G ++C E+
Sbjct: 743 CHYR--------------GSVY------QPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Query: 3647 VWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYREC 3706
+ + DC R P P PAG
Sbjct: 783 ICPEGKEYFDC----------------RFPDP-----------------ELPAG------ 803
Query: 3707 QPGEGCPFSCAHVTQQVGCF-SEGCEEGCHCPEGTFQHRL--ACVQECPCVLTAW 3758
G C +CA++ C S C GC C G + + CP V T +
Sbjct: 804 --GVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIY 856
Score = 60.1 bits (144), Expect = 6e-08
Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 11/105 (10%)
Query: 4665 PEC--EAQDTVFTLDCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPI 4720
P C + D+ DC + CP +C QCL C GC CP G ++ +G C+ +
Sbjct: 325 PACTDKCDDSFVHRDCISCCPPTCTF---EKQCLGSNLHCLDGCYCPDGLVMDNGTCISL 381
Query: 4721 SSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPV 4765
+C CG S ++ +C C CV C Q+CPV
Sbjct: 382 ENCPCGFHGLAYS----VGSKIEQECTECVCVGGVWNCTEQDCPV 422
Score = 60.1 bits (144), Expect = 6e-08
Identities = 34/100 (34%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 4421 DSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNC 4480
D C F C S C C Q C GCYCP GL+ G CI E C C
Sbjct: 329 DKCDDSFVHRDCISCCPPTCT--FEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPC 386
Query: 4481 -WHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGC 4519
+H G+ + G +++ C EC C G +CT Q C
Sbjct: 387 GFH------GLAYSVGSKIEQECTECVCVGGVWNCTEQDC 420
Score = 60.1 bits (144), Expect = 6e-08
Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 41/310 (13%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMGP 252
A C + HY +FDG Y ++ C L +AD + + +C +
Sbjct: 851 AVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKC-----FDNDIVCS 905
Query: 253 EEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRL---------DR 303
+ VLI G+ + P Q G L+ + + G +VV DR
Sbjct: 906 KSVLISVGDTEIYLNDTPYKQK--QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963
Query: 304 TGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSES--GC 361
+I I V + + GLCG ++ +D A FG+SW L ES
Sbjct: 964 KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDET 1023
Query: 362 LDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFA 421
+ E Q P A+ C L F C + + + C
Sbjct: 1024 IKPCEAHQNKFPY---------------AKKECSILYSDIFASCRNVIDVTSFAKNCHED 1068
Query: 422 YCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSL 481
C + G + +C + A+Y C + I I WR C C + Y++ +
Sbjct: 1069 TCNCNLGGD-----CECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC---EYYNEGLGE 1120
Query: 482 CPPSCEAVGQ 491
P + GQ
Sbjct: 1121 GPYMLASYGQ 1130
Score = 57.8 bits (138), Expect = 3e-07
Identities = 39/133 (29%), Positives = 53/133 (39%), Gaps = 12/133 (9%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP--CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGP 2914
C++LA C G H D TQ C C + ML+ H C C++
Sbjct: 656 CNALAHYAYLC-GQHGVPIDFRTQISFCAVVCQKGMLY------HHCSSFCLHSCISLSS 708
Query: 2915 GIECTGFCAPGCTCPPGLFLHNA--SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVS 2972
+C+ CA GC CP G F + C+P C C G +Y G + S C C +
Sbjct: 709 PEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPS-GLCQCSN 767
Query: 2973 GKMACTSERCPVA 2985
G + C P A
Sbjct: 768 GTVKCDELATPSA 780
Score = 57.8 bits (138), Expect = 3e-07
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 3105 SCAELSAPRGTNQTCHPGCHCPSGMLLLN--NVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
SC LS+P + C GC+CP G + N CVP C C + G +Y PG + P
Sbjct: 702 SCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSG 761
Query: 3163 NCSCVSGLI 3171
C C +G +
Sbjct: 762 LCQCSNGTV 770
Score = 57.4 bits (137), Expect = 4e-07
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQV-CQKGCRCPKGSLEQDGGCVPIGH 4116
C C C + CP C+ ++ C + C GC CP G + +G C+ + +
Sbjct: 327 CTDKCDDSFVHRDCISCCPPTCTFEKQ---CLGSNLHCLDGCYCPDGLVMDNGTCISLEN 383
Query: 4117 CDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCP 4155
C C G +++ GS+ + C C C G +CT Q CP
Sbjct: 384 CPC-GFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCP 421
Score = 55.1 bits (131), Expect = 2e-06
Identities = 47/184 (25%), Positives = 59/184 (32%), Gaps = 46/184 (25%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQD--GRCVPISSCRCGLPSANASWE 4735
C++ C HSC L QC C GC CP G+ +D CVPI CRC +
Sbjct: 695 CSSFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGS----V 749
Query: 4736 LAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPG 4795
P + + C C N ++ C P C G
Sbjct: 750 YQPGELIPTPSGLCQCSNGTVKCDELATP--------------------SAVHICPEGKE 789
Query: 4796 VAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICV-QEPCQPGCG 4854
C+ D PE P G V +C C +L C PC GC
Sbjct: 790 YFDCRFPD------------PELPAGGV------NCETTCANLAMNFTCTPSSPCISGCV 831
Query: 4855 CPGG 4858
C G
Sbjct: 832 CAPG 835
Score = 53.9 bits (128), Expect = 4e-06
Identities = 50/180 (27%), Positives = 62/180 (34%), Gaps = 38/180 (21%)
Query: 2624 ADLCQKGLVPP-----CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTR--CLPLSECP 2676
A +CQKG++ C SC+ + CS C EGC CP G DT C+P+ C
Sbjct: 683 AVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 2677 CLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVR 2736
C + PG + C C G + C P C G
Sbjct: 743 CHYRGSVYQPG-ELIPTPSGLCQCSNGTVKCDELATP------------SAVHICPEGKE 789
Query: 2737 ---ARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCL-APG 2792
RF P P GG CE T C +T T S C C+ APG
Sbjct: 790 YFDCRFPDPELPA---GGVNCE----------TTCANLAMNFT-CTPSSPCISGCVCAPG 835
Score = 52.4 bits (124), Expect = 1e-05
Identities = 36/130 (27%), Positives = 52/130 (40%), Gaps = 18/130 (13%)
Query: 3290 YCEGPRAQGEVCQALPCPVTN-------CT--AIEGAEYSPCGPPCPRSCDDLVHCVW-- 3338
YC C P+ + CT + + C CP +C C+
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSN 358
Query: 3339 -RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR 3397
C GCYCP G V+ NG C+ +C C G + G+++ + C C C+ G
Sbjct: 359 LHCLDGCYCPDGLVMD-NGT-CISLENCPCG--FHGLAYSVGSKIEQE--CTECVCVGGV 412
Query: 3398 LNCTDLPCPV 3407
NCT+ CPV
Sbjct: 413 WNCTEQDCPV 422
Score = 51.6 bits (122), Expect = 2e-05
Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 7/102 (6%)
Query: 3315 EGAEYSPCGPPCPRSCDDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLL 3371
+G Y C C SC L C C GC CP G+ CV HC C
Sbjct: 688 KGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC--HY 745
Query: 3372 TGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCP 3413
G + PG + P G C C G + C +L P CP
Sbjct: 746 RGSVYQPGELIPTPSGL--CQCSNGTVKCDELATPSAVHICP 785
Score = 51.2 bits (121), Expect = 3e-05
Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 10/135 (7%)
Query: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQV 1835
C + R C+ + R P D C ++ + + + CP TC + +
Sbjct: 300 CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCI----SCCPPTC---TFEK 352
Query: 1836 TCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDG 1895
C GC+CP+G V+ + G C+ CPC G Y G +I+ +C C+C G
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGG 411
Query: 1896 RPRRCRLNPDCAVDC 1910
C DC V C
Sbjct: 412 -VWNC-TEQDCPVQC 424
Score = 51.2 bits (121), Expect = 3e-05
Identities = 47/172 (27%), Positives = 58/172 (33%), Gaps = 42/172 (24%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHN--GTCVPPTACPCT 4875
C G + C++ C C L C + C GC CP G+ + CVP C C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC- 743
Query: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV---------------- 4919
+ PG ++ C C G C +
Sbjct: 744 ------------HYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYF 791
Query: 4920 DCQVPPGETWQQVAPGELGLCEQTC--LEMNATKTQSNCSSARASGCVCQPG 4969
DC+ P E P CE TC L MN T T S S SGCVC PG
Sbjct: 792 DCRFPDPEL-----PAGGVNCETTCANLAMNFTCTPS---SPCISGCVCAPG 835
Score = 47.4 bits (111), Expect = 4e-04
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 9/94 (9%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLL--EQAGGCIPPEECNC 4480
C +H C S C C + S + C D C GC CP+G + C+P C C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPIFHCRC 743
Query: 4481 WHTSAAGAGMTLAPGDRLQLGCKECECRRGELHC 4514
+ G PG+ + C+C G + C
Sbjct: 744 HY-----RGSVYQPGELIPTPSGLCQCSNGTVKC 772
Score = 47.0 bits (110), Expect = 5e-04
Identities = 132/558 (23%), Positives = 188/558 (33%), Gaps = 121/558 (21%)
Query: 4678 CANQCP-HSCADLW--DRVQCLQGPCRPGCRCPPGQLVQ---DGRCVPISSCRCGLP--- 4728
C C +C + W CL R C C G ++ +C+P C C
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLN--LREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQ 1769
Query: 4729 --SANASWELAPAQAVQLDC-QNCTCVNESLVCPHQECPV--------LGPWSAWSSCSA 4777
+A W + C +N + + C + PV +G W+ CS
Sbjct: 1770 PRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSK 1829
Query: 4778 P-CGGGTMERHR---TCEGGP----GVAPCQAQDTEQRQECNLQPCP-----ECPPGQVL 4824
CG T TC G +P + + EC+ CP EC Q +
Sbjct: 1830 EVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCP-QYKCECDPLKCPSISTPECREDQFM 1888
Query: 4825 SACATSCPCLCWHLQPGAICVQEPC-QPGCGCPGGQLLH---NGT--CVPPTACPCTQHS 4878
PC C+ CV E C +P C G+ L N T C P C C +
Sbjct: 1889 IQVRQEEPC-CF----SPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCCPQYYCVCEPNL 1943
Query: 4879 LPWGL-------TLTLEEQAQELPPGTVLTRNCTRCV---CHGGAFS-----------CS 4917
P L L E + + P NC + C G F+ C
Sbjct: 1944 CPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCEVGEFTAIDHNFQSDCGCI 2003
Query: 4918 LVDCQVPPGETWQQVA---PGELG---LCEQTCLEMNATK-------------TQSNCSS 4958
C+ +Q+V+ PG+ L E C + + T NCS
Sbjct: 2004 QYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYAIECLEEKDNHTGFHTLNFTLVNCSK 2063
Query: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCEC-WHLGRP----HLPGSEWQEACESCLCLS--- 5010
V P S G C + C +H+ + GS W C + C+
Sbjct: 2064 KCDVHQVYTPSP--SDYGCCGTCKNVSCKFHMENGTSVVYAVGSTWHYNCTTYECVKTDE 2121
Query: 5011 GRPVC--TQHCSPLT---CAQGEEMV-LEPGSCCPSCRREAPEEQSPSCQLLTELRNFTK 5064
G + T C P C E +V L CC C+RE CQ + K
Sbjct: 2122 GAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKRE-----ERICQKVIIKSVIRK 2176
Query: 5065 GTCYLDQ-VEVSYCSGYCPSST-HVMPEEPYLQSQCDCCSYRLDPESPVRILN--LRCLG 5120
C + V+ C G CPS+T + + E +L+ C CC E+ VR L+ L C G
Sbjct: 2177 QDCMSQSPINVASCDGKCPSATIYNINIESHLRF-CKCCR-----ENGVRNLSVPLYCSG 2230
Query: 5121 GHTEPVVL---PVIHSCQ 5135
TE + P+ +CQ
Sbjct: 2231 NGTEIMYTLQEPIDCTCQ 2248
Score = 46.6 bits (109), Expect = 6e-04
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQA-GPCVPEDHCECWHLGRPHLPGSE 4998
C +C+ +++ + CS A GC C G F CVP HC C + G + PG
Sbjct: 699 CLHSCISLSSPE---QCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGEL 755
Query: 4999 WQEACESCLCLSGRPVCTQHCSPLT---CAQGEE 5029
C C +G C + +P C +G+E
Sbjct: 756 IPTPSGLCQCSNGTVKCDELATPSAVHICPEGKE 789
Score = 45.8 bits (107), Expect = 0.001
Identities = 36/158 (22%), Positives = 55/158 (34%), Gaps = 37/158 (23%)
Query: 3487 CLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLH-PCGQPCPRS 3545
C + +RACS P + +++ CTD +H C CP +
Sbjct: 300 CRAATEYARACSHAGYP------------IQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347
Query: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAG 3605
C + C ++ C C CP G + +G C+ +C C + A +
Sbjct: 348 C---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSV--------- 395
Query: 3606 SRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
G + C C CV G+ C E DCP
Sbjct: 396 -----------GSKIEQECTECVCVGGVWNCTE-QDCP 421
Score = 45.4 bits (106), Expect = 0.001
Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 4937 LGLCEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP 4995
+ C TC E + +C GC C G G C+ ++C C G +
Sbjct: 341 ISCCPPTCTFEKQCLGSNLHC----LDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSV 395
Query: 4996 GSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
GS+ ++ C C+C+ G CT+ P+ C+
Sbjct: 396 GSKIEQECTECVCVGGVWNCTEQDCPVQCS 425
Score = 44.7 bits (104), Expect = 0.002
Identities = 45/173 (26%), Positives = 60/173 (34%), Gaps = 44/173 (25%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA--CVQ--ECP 3752
C G LY C C SC ++ C S+ C EGC+CPEG F CV C
Sbjct: 686 CQKGMLYHHCS--SFCLHSCISLSSPEQC-SDDCAEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 3753 CVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC-------SLD 3805
C G G+ + T G C C++G + C ++
Sbjct: 743 CHYR--------------------GSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVH 782
Query: 3806 DCFEADGGF-----GPWSPWG--PCSRSCGGLGTRTRSRQCVLTMPTLSGQGC 3851
C E F P P G C +C L + C + P +SG C
Sbjct: 783 ICPEGKEYFDCRFPDPELPAGGVNCETTCANL---AMNFTCTPSSPCISGCVC 832
Score = 43.9 bits (102), Expect = 0.004
Identities = 64/301 (21%), Positives = 95/301 (31%), Gaps = 80/301 (26%)
Query: 4818 CPPGQVLSACATSCP---CLCWHLQPGAICVQEPCQPGCGCPGGQLLH---NGTCVPPTA 4871
CP G+ C C CL C+ + C C G +LH + C+P
Sbjct: 1703 CPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN--LREDCVCKVGTILHRPHSAQCIPEKE 1760
Query: 4872 CPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV----DCQVPPGE 4927
C CT + + Q G + C + + S++ DC P
Sbjct: 1761 CACT------------DSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTP 1808
Query: 4928 TWQQVAPGELGLCEQ-TCLEMNATKTQSNCSSARASGCVCQP----GHFRSQAGPCVPED 4982
++ A +G+ ++ TC + C GH C P+
Sbjct: 1809 VCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGH---SPLSCCPQY 1865
Query: 4983 HCECWHLGRPHLPGSEWQE-------------------ACESC-----LCLSGRPV---- 5014
CEC L P + E +E CESC LC G +
Sbjct: 1866 KCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDL 1925
Query: 5015 ------CTQH---CSP-------LTCAQGEEMVLE--PGSCCPS--CRREAPEEQSPSCQ 5054
C Q+ C P L CA+ +V E G CCP+ C P+C+
Sbjct: 1926 NSTHFCCPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCE 1985
Query: 5055 L 5055
+
Sbjct: 1986 V 1986
Score = 42.7 bits (99), Expect = 0.009
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 5/86 (5%)
Query: 1812 CSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE-GWCVWPRQCP 1869
C +++ C+ C +C +S C D + GC CPEG+ +CV C
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSDDC---AEGCNCPEGKFYEDTLNFCVPIFHCR 742
Query: 1870 CLVDGARYWPGQRIKADCQLCICQDG 1895
C G+ Y PG+ I LC C +G
Sbjct: 743 CHYRGSVYQPGELIPTPSGLCQCSNG 768
Score = 42.0 bits (97), Expect = 0.016
Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 25/113 (22%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPCV 3754
C ++R+C CP +C Q +G + C +GC+CP+G C+ + CPC
Sbjct: 331 CDDSFVHRDCI--SCCPPTCTFEKQCLGS-NLHCLDGCYCPDGLVMDNGTCISLENCPC- 386
Query: 3755 LTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
G G G +++ C C C G +C+ DC
Sbjct: 387 -------------GFHGLAYSVGSKIEQ------ECTECVCVGGVWNCTEQDC 420
Score = 40.8 bits (94), Expect = 0.035
Identities = 76/323 (23%), Positives = 98/323 (30%), Gaps = 86/323 (26%)
Query: 3303 ALPCPVTNCTAIEGAEYSPCGPPC-PRSCDDL-----VHCVWRCQPGCYCPPGQVL-SSN 3355
+L CP EG EY PC PC R+C + C+ + C C G +L +
Sbjct: 1700 SLSCP-------EGKEYQPCVRPCEARTCLNQWFYGHTSCL-NLREDCVCKVGTILHRPH 1751
Query: 3356 GAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEG------RLNCTDLPCPVPG 3409
A C+ C+C D R D C CLE +C + P PV
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPV-- 1809
Query: 3410 GWCP---------WSEWTMCSQPCRGQTRSRSRACACPTP--QHGGAPCTGEAGEAGAQH 3458
C +WT CS+ C C T + CT
Sbjct: 1810 --CEREAEVVMGIIDKWTCCSK----------EVCGCDTTLCETSIPTCTNSQKLIVGHS 1857
Query: 3459 QREACPSYATCPVDGAWGPWGPWSPC--DMCLGQSHRSRACSRPP---TPEGGRPCPGNH 3513
CP Y C D P C D + Q + C P +P P
Sbjct: 1858 PLSCCPQY-KCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVP--- 1913
Query: 3514 TQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQL 3573
C + D S H C CP+ VC+P C PL
Sbjct: 1914 ----LCHDGEFLTVDL---NSTHFC---CPQYY------CVCEPN------LCPMPLLNC 1951
Query: 3574 SQD---------GLCVPPAHCRC 3587
++D G C P HC C
Sbjct: 1952 AEDMNLVKENVSGQCCPTWHCEC 1974
Score = 35.8 bits (81), Expect = 1.1
Identities = 52/237 (21%), Positives = 72/237 (30%), Gaps = 57/237 (24%)
Query: 4055 PMPCEAGCPAGMEVVTCANRCPRR------------CSDLQEGIVCQDDQVCQKGCRCPK 4102
P C CP G E C C R C +L+E VC+ + +
Sbjct: 1696 PDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHR------ 1749
Query: 4103 GSLEQDGGCVPIGHCDCTDAQ------GHSWAPGSQHQDACNNCSC-QAGQL-----SCT 4150
C+P C CTD++ G W G D C C + G + C
Sbjct: 1750 ---PHSAQCIPEKECACTDSEDQPRTAGEIWNGGI---DECTLYKCLENGSIIPIEPDCD 1803
Query: 4151 AQP---CPPPTHCAWSHWSAWSPCSHS-CGPRGQQSRFRSSTSGSWAPECREEQ------ 4200
+P C W+ CS CG ++ + P C Q
Sbjct: 1804 EEPTPVCEREAEVVMGIIDKWTCCSKEVCG-------CDTTLCETSIPTCTNSQKLIVGH 1856
Query: 4201 SQSQPCPQPSC---PPLCLQGTRSRTLGDSW-LQGECQRCSCTPEGVICEDTECAVP 4253
S CPQ C P C + D + +Q + C +CE VP
Sbjct: 1857 SPLSCCPQYKCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVP 1913
Score = 35.4 bits (80), Expect = 1.5
Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 5/52 (9%)
Query: 3319 YSPCGPPCPRSCDDLVHCVWRCQP---GC--YCPPGQVLSSNGAICVQPGHC 3365
Y PC PC ++C D + P GC YCP +L CV P C
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Score = 33.5 bits (75), Expect = 5.6
Identities = 35/148 (23%), Positives = 53/148 (35%), Gaps = 38/148 (25%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCP-RLCLTQG--PGIECTGFCAPGCTCPPGLFLH--- 2935
C+ CPE ++ + PC R CL Q C C C G LH
Sbjct: 1699 CSLSCPEGKEYQPCVR------PCEARTCLNQWFYGHTSCLNL-REDCVCKVGTILHRPH 1751
Query: 2936 NASCLPRSQCPC-------QLHGQLYASGAMARLDSCNNCTCVSG------KMACTSERC 2982
+A C+P +C C + G+++ G +D C C+ + C E
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGG----IDECTLYKCLENGSIIPIEPDCDEEPT 1807
Query: 2983 PVACGWSPWTL-----WSLCS---CSCN 3002
PV + + W+ CS C C+
Sbjct: 1808 PVCEREAEVVMGIIDKWTCCSKEVCGCD 1835
Score = 32.7 bits (73), Expect = 9.6
Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 7/55 (12%)
Query: 3089 MCPRDKQWLDCA-------QGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVC 3136
+CP K++ DC G +C A N TC P C SG + VC
Sbjct: 783 ICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVC 837
Score = 32.7 bits (73), Expect = 9.6
Identities = 33/129 (25%), Positives = 47/129 (36%), Gaps = 31/129 (24%)
Query: 2614 DCELGRVYVSA----DLCQKGLVPP-----CPPS-----CLDPKANRSCS-----GH--C 2652
+C+ YV+ D+C + P CP C+ P R+C GH C
Sbjct: 1673 ECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC 1732
Query: 2653 V---EGCRCPPGLLLH---DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELL 2706
+ E C C G +LH +C+P EC C E+ G +C K
Sbjct: 1733 LNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYK---- 1788
Query: 2707 CQPGGCPLP 2715
C G +P
Sbjct: 1789 CLENGSIIP 1797
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 410 bits (1054), Expect = e-113
Identities = 287/948 (30%), Positives = 428/948 (45%), Gaps = 115/948 (12%)
Query: 465 CERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHC 524
CERL + ++DC L P + +C+++ C CP G + +C A
Sbjct: 225 CERLLTA-EAFADCQDLVPL------EPYLRACQQD---RCRCPGG---DTCVCSTVAE- 270
Query: 525 PCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCA-QALCPAECAVGGDGHYLTFDGRSYSFW 583
+ RQ C+ R G W A A+ P G T G
Sbjct: 271 ---FSRQ-----------CSHAGGRPGNWRTATSAVSP--------GASKTCPGNLVYLE 308
Query: 584 GGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDS---------- 633
G C + V L E D C L T + L D
Sbjct: 309 SGSPCMDTCSHLEVSS----LCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSD 364
Query: 634 GAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVA--YITLDPRHAH 691
G+VL+N V LP + A SV R SS +++ L PV ++TLD
Sbjct: 365 GSVLLNELQVNLPHVTAS-FSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQG 423
Query: 692 QVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQR 751
QVQGLCG F + DDF T +G VE + A FA+ ++ + C + L PC+ + +
Sbjct: 424 QVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA--QSSCHDKLDWLDDPCSLNIES 481
Query: 752 HAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCA 809
+AE C++L + F CH VD +Y RC C C DCLC LS+YAR C
Sbjct: 482 ANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACT 541
Query: 810 QEGASPPWRNQTLCPV---MCPGGQEYRECAPACGQHCGKPED----CGELGSCVAGCNC 862
+G + +C CP Q + C Q C + C E + V GC C
Sbjct: 542 AKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGC 601
Query: 863 PLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAF 922
P D +G+CVP + C C G +++ RC+C++ L R
Sbjct: 602 PDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCT 661
Query: 923 CPRELVYAPGACLLTCDSPSANHSCP---AG-----STDGCVCPPGTVLLDER---CVPP 971
P+ + L P A SC AG GCVCP G L+D+ CV
Sbjct: 662 APKIHMDCSNLTALATSKPRAL-SCQTLAAGYYHTECVSGCVCPDG--LMDDGRGGCVVE 718
Query: 972 DLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFT 1031
CPC H+ Y A I+ DCN C C+ +W CT G C G+ HY+TFDG +
Sbjct: 719 KECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYD 778
Query: 1032 YPGACEYLLVRE------ASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAV 1085
+ G C Y+ V++ + G F++ +N+PCG +G+TC+KA+ + + T + + V
Sbjct: 779 FDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRV 838
Query: 1086 TVN---GVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRV 1142
+ G V YT R G +L++ + G+ ++WD T V ++L+P ++G V
Sbjct: 839 VIQRDEGHHVA----YT-----TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTV 889
Query: 1143 AGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWAR 1202
GLCG+FD ++ND +R ++ + +SW+ +P CP+ P PC++N HR WA
Sbjct: 890 CGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAE 949
Query: 1203 ARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHH 1262
+C L +F++CH++V P+ YE C++D+C CD+GGDCEC CSA+A+YA EC + G
Sbjct: 950 KQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGAC 1009
Query: 1263 VRWRSQELCSLQC-------EGGQVYEACGPTCPPTCHEQHPEPGWHCQV-VACVEGCF- 1313
V WR+ +LC + C E YE CG TC + G H + V+ +EGC+
Sbjct: 1010 VFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN---GIHSNISVSYLEGCYP 1066
Query: 1314 -CPEGTLLHG---GACLEPASCPCEWGRNSFPPGSVL--QKDCGNCTC 1355
CP+ ++ C+ C C +PPG+ + ++ C +C C
Sbjct: 1067 RCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVC 1114
Score = 160 bits (404), Expect = 4e-38
Identities = 179/705 (25%), Positives = 256/705 (36%), Gaps = 148/705 (20%)
Query: 882 CQLGARRYAPGSATMK----------ECNRCICQERGLWNCTARHCPSQAFCPRELVYAP 931
C L YAPG C+ E W+C + P+ P
Sbjct: 1796 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT---------P 1846
Query: 932 GACLLTCDSPSANHSCPAGSTDGCVCPP------------------------GTV-LLDE 966
T PS+ S P T CP TV ++
Sbjct: 1847 SKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKV 1906
Query: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
C PP + C + L +++ C W C C G PHYVTFD
Sbjct: 1907 ECEPPPMPTCSNG----LQPVRVEDPDGCCW----HWECDCY-----CTGWGDPHYVTFD 1953
Query: 1027 GLAFTYPGACEYLLVREAS---GLFTVSAQNLPCGASG-LTCTKALAVRLEG-----TVV 1077
GL ++Y G C Y+LV E S F V N C + ++C + L VR E V
Sbjct: 1954 GLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTV 2013
Query: 1078 HMLRGRA-VTVNGVSVTPPKVYTGPGLSLRRAGL-FLLLSTHLGLTLLWDGGTRVLVQLS 1135
HM+ + V VN +V P Y GL + ++G+ +++ LG+ + ++G + +
Sbjct: 2014 HMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPY 2071
Query: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGD----- 1186
+F G CG S+D G + E AA W ++ P CP
Sbjct: 2072 HRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRP 2131
Query: 1187 ---LPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCE 1243
+P H+ C + LF CHA VPPQ +Y+ C++D+C G E
Sbjct: 2132 AVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM-PGSSLE 2190
Query: 1244 CLCSAIATYADECARHGHHVRWRSQE--LCSLQCEGGQVYEACGPTCPPTCHEQHPEPGW 1301
C+++ YA CA+ + WR+ C ++C + Y+ACGP PTC +
Sbjct: 2191 --CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQ-- 2246
Query: 1302 HCQVVACVEGCFCPEGTLLHGG---------ACLEPASCPCEWGRNSFPPGSVLQKDCGN 1352
VEGCFCPEGT+ + C+ P + P E+G + + DC N
Sbjct: 2247 --NNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEH-------FEFDCKN 2297
Query: 1353 CTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGW----------LCDNQDDC 1402
C C E GG G C+ C++ HCV G C N C
Sbjct: 2298 CVCLE-----GGSGIICQP--KRCSQKPVT-----HCVEDGTYLATEVNPADTCCNITVC 2345
Query: 1403 GDGSD---EEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLAC 1459
+ E+ P E + G C P C+ + C G E P C
Sbjct: 2346 KCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPF-YWCESKGVCVHGNAEYQPGSPVYSSKC 2404
Query: 1460 ADGRCLPPALLCDGHPDCLDAADEESCLGQVTC--VPGEVSCVDG 1502
D C+ C D D + L + C VP SC G
Sbjct: 2405 QD--CV-----------CTDKVDNNTLLNVIACTHVPCNTSCSPG 2436
Score = 137 bits (346), Expect = 2e-31
Identities = 136/489 (27%), Positives = 192/489 (39%), Gaps = 55/489 (11%)
Query: 553 WHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG--QLLILLEHGAC 610
WH C C GD HY+TFDG YS+ G C Y LV++ + +++ C
Sbjct: 1933 WHWE---CDCYCTGWGDPHYVTFDGLYYSYQGN--CTYVLVEEISPSVDNFGVYIDNYHC 1987
Query: 611 DAG---SCLHAISVSLEDTHIQLRD------SGAVLVNGQDVGLPWIGAEGLSVRRASSA 661
D SC + V E + ++ V VN Q V LP+ GL V ++
Sbjct: 1988 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY-KKYGLEVYQSGIN 2046
Query: 662 FLLLRWPGAQVLWGLSDPVAYITLD-PRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIA 720
+++ P VL + + L R + +G CGT T DD + P+G++ ++
Sbjct: 2047 YVV-DIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCE 2105
Query: 721 AFASKFQV--AGKGRCPSEDSALLSPCTT-------HSQRHAFAEAACAILHSSVFQECH 771
A A ++ V K CP S P T + C ++ S+F +CH
Sbjct: 2106 AAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCH 2165
Query: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQT--LCPVMCPG 829
LV + +Y C+ C PGS C L AYA CAQ+ WRN T C V CP
Sbjct: 2166 ALVPPQHYYDACVFDSCFM-PGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPS 2224
Query: 830 GQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
+EY+ C PA C V GC CP G + G V C C +G
Sbjct: 2225 HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC-VGPDNV 2283
Query: 890 AP--GSATMKECNRCICQERGLW-NCTARHCPSQAFCPRELVYAPGACLLTCDSPS---A 943
G +C C+C E G C + C + P G L T +P+
Sbjct: 2284 PREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQK---PVTHCVEDGTYLATEVNPADTCC 2340
Query: 944 NHSCPAGSTDGC-----VCPPG----TVLLDERCVPPDLCP----CRHSGQWYLPNATI- 989
N + +T C VCP G + ++ RC P C C H Y P + +
Sbjct: 2341 NITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVY 2400
Query: 990 QEDCNVCVC 998
C CVC
Sbjct: 2401 SSKCQDCVC 2409
Score = 130 bits (327), Expect = 3e-29
Identities = 94/315 (29%), Positives = 143/315 (45%), Gaps = 23/315 (7%)
Query: 1014 CQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCG---ASGLTCTKALAV 1070
C G HY TFDG F +PG C+Y + G + A +L G A +++ +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
Query: 1071 RLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRV 1130
++ +++ R AV +NG V+ P + PGL + ++ + + + GLTL+W+ +
Sbjct: 97 TIKDDTIYLTRHLAV-LNGAVVSTP--HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
Query: 1131 LVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSP--LCPEPGDLP 1188
+++L +FR GLCGD++G S GVL E P +C +P +
Sbjct: 154 MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEV 213
Query: 1189 HPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
P + + HRA R L F C VP + + C D C C GGD C+CS
Sbjct: 214 APASCSEHRAECER----LLTAEAFADCQDLVPLEPYLRACQQDRCRC-PGGD-TCVCST 267
Query: 1249 IATYADECARHGHHV-RWRSQEL-----CSLQCEGGQVYEACGPTCPPTCHEQHPEPGWH 1302
+A ++ +C+ G WR+ S C G VY G C TC H E
Sbjct: 268 VAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC--SHLEVSSL 325
Query: 1303 CQVVACVEGCFCPEG 1317
C+ ++GCFCPEG
Sbjct: 326 CEEHR-MDGCFCPEG 339
Score = 129 bits (325), Expect = 6e-29
Identities = 84/272 (30%), Positives = 130/272 (47%), Gaps = 27/272 (9%)
Query: 294 GLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR 353
G+ + V+L + +++D GQ QGLCG +NG DDF G + A F N+W+
Sbjct: 400 GVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWK 459
Query: 354 LPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSP 411
++S C D ++ DP L ++E + A+ C L E PFG+CH+ V P
Sbjct: 460 ---AQSSCHDKLDWLD--DPCSL---NIESANY---AEHWCSLLKKTETPFGRCHSAVDP 508
Query: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCER---L 468
AEY++ C + C + + +CA +SY +AC + + + + C +
Sbjct: 509 AEYYKRCKYDTC-------NCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGS 561
Query: 469 CPGGQLYSDCVSLCPPSCEAVGQGEEESCRE--ECVSGCECPRGLFWNGT-LCVPAAHCP 525
CP Q++ ++ C +C ++ + + C E V GC CP F + CVP A C
Sbjct: 562 CPNSQVFLYNLTTCQQTCRSLSEADSH-CLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCS 620
Query: 526 CYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQ 557
CY+ GD V + CVCRDGR HC Q
Sbjct: 621 CYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQ 652
Score = 113 bits (283), Expect = 4e-24
Identities = 100/399 (25%), Positives = 156/399 (39%), Gaps = 62/399 (15%)
Query: 194 TCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADSTWAVHL--------TPGDRCPQ 241
TC+ + HY TFDG++Y F G C+Y+ G S + + T G C +
Sbjct: 760 TCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSK 819
Query: 242 PGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRL 301
++ MG E+ ++ K ++V + + + +G +LV+ G++V
Sbjct: 820 ---AIKIFMGRTELKLED-----KHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIW 871
Query: 302 DRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGC 361
D+ ++ I + G GLCG ++ +DF + FGNSW+ C
Sbjct: 872 DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK---EAPTC 928
Query: 362 LDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFA 421
D + C + P H R+ A+ C L F CH++V P ++EAC+
Sbjct: 929 PDVSTNPEPC--------SLNP-HRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHD 979
Query: 422 YCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSL 481
C+ G + C+ ASY Q C + + WR P C C Y +
Sbjct: 980 SCSCDTGGD-----CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD----YYNPPHE 1030
Query: 482 CPPSCEAVGQGEEESCR--------------EECVSGCECPRGLFWNG-TLCVPAAHCPC 526
C E G E+CR E C C R ++ CV A C C
Sbjct: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
Query: 527 YYCRQRYVPGDTV--RQLCNPCVCRDGRWHCAQALCPAE 563
Y Y PG +V + C CVC + +Q +C E
Sbjct: 1091 YVEDTHYPPGASVPTEETCKSCVCTNS----SQVVCRPE 1125
Score = 102 bits (253), Expect = 1e-20
Identities = 106/401 (26%), Positives = 151/401 (37%), Gaps = 68/401 (16%)
Query: 188 HQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL----AGAADSTWA----VHLTPGDR- 238
H C W HY TFDG +Y + G CTY+L + + D+ H P D+
Sbjct: 1934 HWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKV 1993
Query: 239 -CP---------QPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEG----QSWLLHGLSLQW 284
CP Q + V M P +V +Q +V G QS + + + +
Sbjct: 1994 SCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
Query: 285 LGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAML 344
LG LV GL VRL H T+G CG DD + P G +
Sbjct: 2054 LG-VLVSYNGLSFSVRLPY---------HRFGNNTKGQCGTCTNTTSDDCILPSGEIVSN 2103
Query: 345 AATFGNSWRL-PGSESGCLDAVEVAQGCDPLGLIDADVEPG------HLRAEAQDVCHQL 397
+ W + S+ C + + A PG H +C +
Sbjct: 2104 CEAAADQWLVNDPSKPHCPHSSSTTKR-------PAVTVPGGGKTTPHKDCTPSPLCQLI 2156
Query: 398 LEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI 457
+ F QCHA V P Y++AC+F C M GS E CA+ +Y CA+++I +
Sbjct: 2157 KDSLFAQCHALVPPQHYYDACVFDSC--FMPGSSLE------CASLQAYAALCAQQNICL 2208
Query: 458 RWRK--PGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNG 515
WR G C CP + Y C P+C++ + + V GC CP G
Sbjct: 2209 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV---LVEGCFCPEGTMNYA 2265
Query: 516 ---TLCVPAAHC--PCYYCRQRYVPGDTVRQLCNPCVCRDG 551
+CV C P R+ G+ C CVC +G
Sbjct: 2266 PGFDVCVKTCGCVGPDNVPREF---GEHFEFDCKNCVCLEG 2303
Score = 86.7 bits (213), Expect = 6e-16
Identities = 83/317 (26%), Positives = 132/317 (41%), Gaps = 29/317 (9%)
Query: 564 CAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQD----YVKGQLLILLEHGACDAGSCLHAI 619
C+ G+ HY TFDG + F G C Y+ D Y + + + G +A + + +I
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPG--LCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 620 SVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679
++++D I L AVL NG V P + GL + ++ + + G ++W D
Sbjct: 95 LLTIKDDTIYLTRHLAVL-NGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
Query: 680 VAYITLDPRHAHQVQGLCGTFTQNQQ-DDFLTPAGDVETSIAAFASKFQVAGKGRCPSED 738
+ + LD + + GLCG + Q +FL+ V S F + ++ +
Sbjct: 153 L-MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNMQKINQPDVVCEDP 209
Query: 739 SALLSPCTTHSQRHAFAEAAC-AILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCL 797
++P + R A C +L + F +C LV EP+ C C C G C+
Sbjct: 210 EEEVAPASCSEHR-----AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCV 264
Query: 798 CPVLSAYARRCAQEGASP-PWRNQTL-----CPVMCPGGQEYRECAPACGQHCGKPED-- 849
C ++ ++R+C+ G P WR T CPG Y E C C E
Sbjct: 265 CSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSS 324
Query: 850 -CGELGSCVAGCNCPLG 865
C E + GC CP G
Sbjct: 325 LCEE--HRMDGCFCPEG 339
Score = 79.7 bits (195), Expect = 7e-14
Identities = 83/333 (24%), Positives = 128/333 (38%), Gaps = 47/333 (14%)
Query: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTW---AVHLTPGD---RCPQPGHCQRV 248
C++W FHY+TFDG + F G C Y A ++ AVHL G P +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
Query: 249 TMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSIS 308
T+ + + + + G +V GL ++ + + G+ + +R ++
Sbjct: 97 TIKDDTIYLTRHLAVLNGAVV--STPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALM 154
Query: 309 ISVDHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEV 367
+ +D + T GLCG YNG +F+ G+ FGN ++ + C D E
Sbjct: 155 LELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQPDVVCEDPEE- 211
Query: 368 AQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGA 426
+V P +E + C +LL F C V Y AC C
Sbjct: 212 ------------EVAPASC-SEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCR-- 256
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIR---WR------KPGFCERLCPGGQLYSD 477
G VC+T A + + C+ H R WR PG + CPG +Y +
Sbjct: 257 -----CPGGDTCVCSTVAEFSRQCS--HAGGRPGNWRTATSAVSPG-ASKTCPGNLVYLE 308
Query: 478 CVSLCPPSCEAVGQGEEESCREECVSGCECPRG 510
S C +C + C E + GC CP G
Sbjct: 309 SGSPCMDTCSHL--EVSSLCEEHRMDGCFCPEG 339
Score = 79.3 bits (194), Expect = 9e-14
Identities = 65/228 (28%), Positives = 77/228 (33%), Gaps = 47/228 (20%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLL-HNGTCVPPTACPC 4874
CP QV T+C C L E P GCGCP L G CVP C C
Sbjct: 562 CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC 621
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV-----DCQVPPGETW 4929
L L G V+ R RCVC G C + C P
Sbjct: 622 YHRGL-------------YLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPK---- 664
Query: 4930 QQVAPGELGLCEQTCLEMNATKTQS----NCSSARA--------SGCVCQPGHFRSQAGP 4977
C + A T +C + A SGCVC G G
Sbjct: 665 ----------IHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGG 714
Query: 4978 CVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025
CV E C C H + G++ + C +C C GR VCTQ TC+
Sbjct: 715 CVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCS 762
Score = 63.9 bits (154), Expect = 4e-09
Identities = 40/159 (25%), Positives = 58/159 (36%), Gaps = 31/159 (19%)
Query: 1232 DACGC------DSGGDC----ECLC----------SAIATYADECARHGHHVRWRSQELC 1271
D CGC D G C +C C + + C + R L
Sbjct: 597 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 656
Query: 1272 SLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA-------CVEGCFCPEGTLLHG-G 1323
C +++ C T CQ +A CV GC CP+G + G G
Sbjct: 657 GQSCTAPKIHMDCSNL---TALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRG 713
Query: 1324 ACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
C+ CPC + + G+ ++ DC CTC+ G+W C
Sbjct: 714 GCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVC 752
Score = 62.4 bits (150), Expect = 1e-08
Identities = 53/194 (27%), Positives = 73/194 (37%), Gaps = 26/194 (13%)
Query: 4338 MAKADPTCNSTFLHLDTQGCYSGPCPEE---CVWSSWSSWTRCSCRVLVQQRYRHQGPAS 4394
+++AD C F +D GC +E CV +CSC R +
Sbjct: 582 LSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCV-----PLAKCSC----YHRGLYLEAGD 632
Query: 4395 RGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPP 4454
R C DG C SCT P + H S L + CQ L
Sbjct: 633 VVVRQEERCVCRDGRLH-CRQIRLIGQSCTAP-KIHMDCSNLTALATSKPRALSCQTLAA 690
Query: 4455 ------CQPGCYCPKGLLEQA-GGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECEC 4507
C GC CP GL++ GGC+ +EC C H + + G ++++ C C C
Sbjct: 691 GYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDL-----YSSGAKIKVDCNTCTC 745
Query: 4508 RRGELHCTSQGCQG 4521
+RG CT C G
Sbjct: 746 KRGRWVCTQAVCHG 759
Score = 61.6 bits (148), Expect = 2e-08
Identities = 27/66 (40%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 2922 CAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSE 2980
C GC CP GL C+ +CPC + LY+SGA ++D CN CTC G+ CT
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD-CNTCTCKRGRWVCTQA 755
Query: 2981 RCPVAC 2986
C C
Sbjct: 756 VCHGTC 761
Score = 58.2 bits (139), Expect = 2e-07
Identities = 100/457 (21%), Positives = 151/457 (33%), Gaps = 119/457 (26%)
Query: 4703 GCRCPPGQL-VQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQ 4761
GC CP G + G V + +C C P N E + + DC+NC C+
Sbjct: 2254 GCFCPEGTMNYAPGFDVCVKTCGCVGPD-NVPREFG--EHFEFDCKNCVCLEG------- 2303
Query: 4762 ECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPG 4821
G G + + + C P V C T E N P C
Sbjct: 2304 ------------------GSGIICQPKRCSQKP-VTHCVEDGTYLATEVN--PADTCCNI 2342
Query: 4822 QVLSACATSC---PCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHS 4878
V + C P +C P V+ PG CP G CV A
Sbjct: 2343 TVCKCNTSLCKEKPSVC----PLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA------- 2391
Query: 4879 LPWGLTLTLEEQAQELPPGT-VLTRNCTRCVCHG--------GAFSCSLVDCQVPPGETW 4929
E PG+ V + C CVC +C+ V C +
Sbjct: 2392 --------------EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGF 2437
Query: 4930 QQV-APGELGLCEQTCLEMNATKTQSNCSSARASG--CVCQPGHFRSQAGPCVPEDHCEC 4986
+ + APGE C + C Q++C R + +PG F+S P+++C
Sbjct: 2438 ELMEAPGE---CCKKC-------EQTHCIIKRPDNQHVILKPGDFKSD-----PKNNCTF 2482
Query: 4987 WHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGS-------CCP 5039
+ SC+ + + + + S +TC + + PGS CC
Sbjct: 2483 F-----------------SCVKIHNQLISS--VSNITCPNFDASICIPGSITFMPNGCCK 2523
Query: 5040 SCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCD 5099
+C E C + + C V +++CSG C + + L C
Sbjct: 2524 TCTPR--NETRVPCSTVPVTTEVSYAGC-TKTVLMNHCSGSCGTFVMYSAKAQALDHSCS 2580
Query: 5100 CCSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQC 5136
CC + ++ R + L C G + I SCQC
Sbjct: 2581 CCK---EEKTSQREVVLSCPNGGSLTHTYTHIESCQC 2614
Score = 54.7 bits (130), Expect = 2e-06
Identities = 49/180 (27%), Positives = 63/180 (35%), Gaps = 20/180 (11%)
Query: 1730 QNCPGPEHQSQACFTAACPVDG----------EWSTWSPWSVCSEPCRGTMTRQRQCHSP 1779
Q C C PVDG E P + CS RG
Sbjct: 577 QTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVR 636
Query: 1780 QNGGRTCAALPGGLHSTRQTKPCPQDGCP---NATCSGELMFQPCAPCPLTCDDISGQVT 1836
Q C G LH RQ + Q + CS P L+C ++
Sbjct: 637 QE--ERCVCRDGRLHC-RQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYY 693
Query: 1837 CPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGR 1896
C S GC CP+G + G CV ++CPC+ + Y G +IK DC C C+ GR
Sbjct: 694 ---HTECVS-GCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGR 749
Score = 53.9 bits (128), Expect = 4e-06
Identities = 66/276 (23%), Positives = 94/276 (34%), Gaps = 76/276 (27%)
Query: 4654 WAQESCNG--GPCPECEAQDTVFTLDCANQCPHSCADLWDR-VQCLQGPCR-PGCRCPPG 4709
W + CN G CP + VF + C +C L + CL+G GC CP
Sbjct: 550 WREHVCNKDVGSCPNSQ----VFLYNLTT-CQQTCRSLSEADSHCLEGFAPVDGCGCPDH 604
Query: 4710 QLVQD-GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP 4768
+ + GRCVP++ C C + L V + C C + L C ++ ++G
Sbjct: 605 TFLDEKGRCVPLAKCSC----YHRGLYLEAGDVVVRQEERCVCRDGRLHC--RQIRLIG- 657
Query: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
SC+AP + H C L+A A
Sbjct: 658 ----QSCTAP------KIHMDCSN-------------------------------LTALA 676
Query: 4829 TSCP--CLCWHLQPGAICVQEPCQPGCGCPGGQLLH-NGTCVPPTACPCTQHSLPWGLTL 4885
TS P C L G + C GC CP G + G CV CPC ++
Sbjct: 677 TSKPRALSCQTLAAGYYHTE--CVSGCVCPDGLMDDGRGGCVVEKECPCVHNN------- 727
Query: 4886 TLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
G + +C C C G + C+ C
Sbjct: 728 ------DLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 757
Score = 53.9 bits (128), Expect = 4e-06
Identities = 62/271 (22%), Positives = 82/271 (30%), Gaps = 93/271 (34%)
Query: 3542 CPRSCQDLSPG-SVCQPGSVGCQPTCGCPLGQ-LSQDGLCVPPAHCRCQYQPGAMGIPEN 3599
C ++C+ LS S C G CGCP L + G CVP A C C Y G
Sbjct: 575 CQQTCRSLSEADSHCLEGFAPVDG-CGCPDHTFLDEKGRCVPLAKCSC-YHRGLY----- 627
Query: 3600 QSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSV 3659
LE G+VV + C C G L C+++
Sbjct: 628 --------------LEAGDVVVRQEERCVCRDGRLHCRQI-------------------- 653
Query: 3660 SCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHV 3719
+L + C P +T R C
Sbjct: 654 ------RLIGQSCTAPKIHMDCSNLTALATSKPRALSCQ--------------------- 686
Query: 3720 TQQVGCFSEGCEEGCHCPEGTFQH-RLACV--QECPCVLTAWLLQELGATIGDPGQPLGP 3776
T G + C GC CP+G R CV +ECPCV
Sbjct: 687 TLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN-------------------- 726
Query: 3777 GDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
D SG ++ C C+C G+ C+ C
Sbjct: 727 NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 757
Score = 53.1 bits (126), Expect = 7e-06
Identities = 59/240 (24%), Positives = 89/240 (37%), Gaps = 38/240 (15%)
Query: 1812 CSGELMFQPCAPCPL-TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPC 1870
C +Q C P TC S Q + GC+CPEG + + G+ V + C C
Sbjct: 2222 CPSHREYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC 2277
Query: 1871 L-VDGARYWPGQRIKADCQLCICQDG------RPRRCRLNP--DCAVDCGW--SSWSPWA 1919
+ D G+ + DC+ C+C +G +P+RC P C D + + +P
Sbjct: 2278 VGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
Query: 1920 KCLG----PCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEG---CEHQGQ 1972
C C + + P G + + R C CE C H
Sbjct: 2338 TCCNITVCKCNTSLCK------EKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA 2391
Query: 1973 VHRVGERWHGGPCRVCQC--------LHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHC 2024
++ G + C+ C C L N+ A C+ SC G+ L+E GE C C
Sbjct: 2392 EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIA-CTHVPCNTSCSPGFELMEAPGECCKKC 2450
Score = 50.4 bits (119), Expect = 4e-05
Identities = 95/391 (24%), Positives = 127/391 (32%), Gaps = 79/391 (20%)
Query: 4713 QDGRCVPISSCRCGLPSAN--ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWS 4770
Q G C +S C LPS ++ E A Q + D C PH P
Sbjct: 2081 QCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHC-------PHSSSTTKRP-- 2131
Query: 4771 AWSSCSAPCGGGTMERHRTCEGGPGV--------APCQAQDTEQR--QECNLQPC----- 4815
+ + P GGG H+ C P A C A Q C C
Sbjct: 2132 ---AVTVP-GGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS 2187
Query: 4816 -PECPPGQVLSA-CATSCPCLCWHLQPGAICVQEPCQP-----GCG------CPGGQLLH 4862
EC Q +A CA CL W C+ E C CG C
Sbjct: 2188 SLECASLQAYAALCAQQNICLDWRNHTHGACLVE-CPSHREYQACGPAEEPTCKSSSSQQ 2246
Query: 4863 NGTCVPPTACPCTQHSLPW--GLTLTLEEQAQELPP------GTVLTRNCTRCVC--HGG 4912
N T V C C + ++ + G + ++ P G +C CVC G
Sbjct: 2247 NNT-VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGS 2305
Query: 4913 AFSCSLVDCQVPPG----ETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQP 4968
C C P E +A E+ + C N T + N S + VC
Sbjct: 2306 GIICQPKRCSQKPVTHCVEDGTYLAT-EVNPADTCC---NITVCKCNTSLCKEKPSVCPL 2361
Query: 4969 GH---FRSQAGPCVPEDHCE----CWHLGRPHLPGSE-WQEACESCLC--------LSGR 5012
G + G C P CE C H + PGS + C+ C+C L
Sbjct: 2362 GFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNV 2421
Query: 5013 PVCTQHCSPLTCAQGEEMVLEPGSCCPSCRR 5043
CT +C+ G E++ PG CC C +
Sbjct: 2422 IACTHVPCNTSCSPGFELMEAPGECCKKCEQ 2452
Score = 48.9 bits (115), Expect = 1e-04
Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 19/103 (18%)
Query: 3090 CPRDKQWLDCAQGPA---------SCAELSAPRGTNQT-CHPGCHCPSGMLLLNNV-CVP 3138
C K +DC+ A SC L+A G T C GC CP G++ CV
Sbjct: 660 CTAPKIHMDCSNLTALATSKPRALSCQTLAA--GYYHTECVSGCVCPDGLMDDGRGGCVV 717
Query: 3139 TQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAE 3181
++CPC H LY G+ + C C+C G W C +
Sbjct: 718 EKECPCVHNNDLYSSGAKIKVDCNTCTCKRG------RWVCTQ 754
Score = 48.1 bits (113), Expect = 2e-04
Identities = 69/287 (24%), Positives = 103/287 (35%), Gaps = 69/287 (24%)
Query: 2474 GECLSAERRCDLRPDCQ-DGSDEDGCVDCVLAPWSVWSSCSRSCGLGLTFQRQELLRPPL 2532
G C SA + C+ D + DC+ A S ++ + G+ L R+ + +
Sbjct: 500 GRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDV 559
Query: 2533 PGGSCPRDR---FRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKN 2589
GSCP + + +C Q C S+S H C++
Sbjct: 560 --GSCPNSQVFLYNLTTC-QQTCR--------------SLSEADSH------CLEGFAPV 596
Query: 2590 GGAPCPGAS--QERAPC-GLQPCS---GGTDCELGRVYVSAD---LCQKGL-----VPPC 2635
G CP + E+ C L CS G E G V V + +C+ G +
Sbjct: 597 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 656
Query: 2636 PPSCLDPKANRSCSG------------------------HCVEGCRCPPGLLLHDTR--C 2669
SC PK + CS CV GC CP G L+ D R C
Sbjct: 657 GQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG-LMDDGRGGC 715
Query: 2670 LPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPC 2716
+ ECPC+ +L G + +C+ C C++G +C C C
Sbjct: 716 VVEKECPCVHNNDLYSSGAKIKV-DCNTCTCKRGRWVCTQAVCHGTC 761
Score = 46.6 bits (109), Expect = 6e-04
Identities = 46/200 (23%), Positives = 72/200 (36%), Gaps = 15/200 (7%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIV-CQDDQVCQKGCRCPKGS-LEQDGGCVPIGHCDC 4119
CP + C + C L E C + GC CP + L++ G CVP+ C C
Sbjct: 562 CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC 621
Query: 4120 TDAQGHSWAPGSQHQDACNNCSCQAGQLSC-----TAQPC-PPPTHCAWSHWSAWS---P 4170
+G G C C+ G+L C Q C P H S+ +A + P
Sbjct: 622 YH-RGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKP 680
Query: 4171 CSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQ 4230
+ SC SG P+ + + + CP C+ + G + ++
Sbjct: 681 RALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP--CVHNNDLYSSG-AKIK 737
Query: 4231 GECQRCSCTPEGVICEDTEC 4250
+C C+C +C C
Sbjct: 738 VDCNTCTCKRGRWVCTQAVC 757
Score = 44.7 bits (104), Expect = 0.002
Identities = 35/120 (29%), Positives = 48/120 (40%), Gaps = 15/120 (12%)
Query: 3290 YCEGPRAQGEVCQA--LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWR--CQPGCY 3345
+C R G+ C A + +N TA+ ++ P SC L + C GC
Sbjct: 649 HCRQIRLIGQSCTAPKIHMDCSNLTALATSK------PRALSCQTLAAGYYHTECVSGCV 702
Query: 3346 CPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
CP G + G CV C C+ + GA++ CN CTC GR CT C
Sbjct: 703 CPDGLMDDGRGG-CVVEKECPCVH--NNDLYSSGAKIKVD--CNTCTCKRGRWVCTQAVC 757
Score = 44.3 bits (103), Expect = 0.003
Identities = 49/205 (23%), Positives = 70/205 (34%), Gaps = 35/205 (17%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGC-VPIGH 4116
C CP+ E C C Q++ V +GC CP+G++ G V +
Sbjct: 2218 CLVECPSHREYQACGPAEEPTCKSSSSQ---QNNTVLVEGCFCPEGTMNYAPGFDVCVKT 2274
Query: 4117 CDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQP--C--PPPTHCAWSHW---SAWS 4169
C C G + C NC C G QP C P THC + +
Sbjct: 2275 CGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVN 2334
Query: 4170 PCSHSCGPRGQQSRFRSSTSGSWAPECREEQS--------QSQPCPQPSCP-------PL 4214
P C + + +TS C+E+ S +S+ P CP +
Sbjct: 2335 PADTCC----NITVCKCNTS-----LCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGV 2385
Query: 4215 CLQGTRSRTLGDSWLQGECQRCSCT 4239
C+ G G +CQ C CT
Sbjct: 2386 CVHGNAEYQPGSPVYSSKCQDCVCT 2410
Score = 40.8 bits (94), Expect = 0.035
Identities = 28/87 (32%), Positives = 32/87 (36%), Gaps = 5/87 (5%)
Query: 3088 GMCPRDKQWL----DCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLL-LNNVCVPTQDC 3142
G CP + +L C Q S +E + GC CP L CVP C
Sbjct: 560 GSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKC 619
Query: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSG 3169
C H G G VVR E C C G
Sbjct: 620 SCYHRGLYLEAGDVVVRQEERCVCRDG 646
Score = 40.0 bits (92), Expect = 0.060
Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 32/108 (29%)
Query: 3697 CPAGRLYRECQPGEG--CPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRL---ACVQEC 3751
CP+ R Y+ C P E C S + V EGC CPEGT + CV+ C
Sbjct: 2222 CPSHREYQACGPAEEPTCKSSSSQQNNTV------LVEGCFCPEGTMNYAPGFDVCVKTC 2275
Query: 3752 PCVLTAWLLQELGATIGDPGQPLGPGD-ELDSGQTLRTSCGNCSCAHG 3798
CV GP + + G+ C NC C G
Sbjct: 2276 GCV--------------------GPDNVPREFGEHFEFDCKNCVCLEG 2303
Score = 39.3 bits (90), Expect = 0.10
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 19/95 (20%)
Query: 862 CPLGLLWDPEGQCVPPSLCP---------CQLGARRYAPGSATMK-ECNRCICQER---- 907
CPLG ++ + + VP CP C G Y PGS +C C+C ++
Sbjct: 2359 CPLG--FEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNN 2416
Query: 908 GLWNCTA-RHCPSQAFCPR--ELVYAPGACLLTCD 939
L N A H P C EL+ APG C C+
Sbjct: 2417 TLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCE 2451
Score = 37.7 bits (86), Expect = 0.30
Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 21/124 (16%)
Query: 3326 CPRSCDDLV----HCVWRCQP--GCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPG 3379
C ++C L HC+ P GC CP L G CV CSC +H G
Sbjct: 575 CQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGR-CVPLAKCSC--------YHRG 625
Query: 3380 ARLARPDGC----NHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRAC 3435
L D C C +GRL+C + + G C + M S+ RA
Sbjct: 626 LYLEAGDVVVRQEERCVCRDGRLHCRQI--RLIGQSCTAPKIHMDCSNLTALATSKPRAL 683
Query: 3436 ACPT 3439
+C T
Sbjct: 684 SCQT 687
Score = 37.0 bits (84), Expect = 0.51
Identities = 53/234 (22%), Positives = 76/234 (32%), Gaps = 67/234 (28%)
Query: 1732 CPGPEHQSQACFTAA--CPVDGEWSTWSPWSVCSEPCRGTMTRQRQC----HSPQNGGRT 1785
C +H+S FT V E + W + C T C H +
Sbjct: 893 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPDVSTNPEPCSLNPHRRSWAEKQ 951
Query: 1786 CAALPGGL----HSTRQTKP----CPQDGCPNAT-------CSGELMF-QPCAP------ 1823
C+ L + HS KP C D C T CS + Q C
Sbjct: 952 CSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF 1011
Query: 1824 ------CPLTCDDISGQVTCPPDW---PCGS---------------------PGCW--CP 1851
CP+ CD + C +W PCG+ GC+ CP
Sbjct: 1012 WRTPDLCPIFCDYYNPPHEC--EWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCP 1069
Query: 1852 EGQVLGSEGW--CVWPRQCPCLVDGARYWPGQRIKAD--CQLCICQDGRPRRCR 1901
+ + + E CV +C C V+ Y PG + + C+ C+C + CR
Sbjct: 1070 KDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
Score = 37.0 bits (84), Expect = 0.51
Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 6/91 (6%)
Query: 2312 GQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTL----PPGMAAVTVVP 2367
G P + T T P++ S P + Q +T P E+ TL PP + + P
Sbjct: 1653 GSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 1712
Query: 2368 PH-PVTPATPAGQSVAPGPFPPVQCGPGQTP 2397
P P P T +G P P P TP
Sbjct: 1713 PSTPTAPTTTSGGHTLSPP-PSTTTSPPGTP 1742
Score = 37.0 bits (84), Expect = 0.51
Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 30/113 (26%)
Query: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLC--QDLPPCQP------------GCYCPK 4463
C++ + + H G+ C C +H +Q C + P C+ GC+CP+
Sbjct: 2201 CAQQNICLDWRNHTHGA-CLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPE 2259
Query: 4464 GLLEQAGG---CIPPEECNCWHTSAAGAGMTLAP---GDRLQLGCKECECRRG 4510
G + A G C+ + C C G P G+ + CK C C G
Sbjct: 2260 GTMNYAPGFDVCV--KTCGC-------VGPDNVPREFGEHFEFDCKNCVCLEG 2303
Score = 35.8 bits (81), Expect = 1.1
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 20/144 (13%)
Query: 3090 CPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDCPCAH 3146
CP +++ C + S+ + N GC CP G + +VCV T C C
Sbjct: 2222 CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVG 2279
Query: 3147 EGHLYPP-GSTVVRPCENCSCV---SGLIA---NCSSWP---CAE-GEPTWSPWTPWSQC 3195
++ G C+NC C+ SG+I CS P C E G + P C
Sbjct: 2280 PDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
Query: 3196 SASCGPARCH-RHRFCARSPSAVP 3218
C C C PS P
Sbjct: 2340 ---CNITVCKCNTSLCKEKPSVCP 2360
Score = 35.4 bits (80), Expect = 1.5
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 21/106 (19%)
Query: 4693 VQCLQGPCRPGCRCPPGQLVQDG---RCVPISSCRCGLPSANASWELAPAQAVQLD--CQ 4747
V L+G C P RCP + + + +CV C C + + P +V + C+
Sbjct: 1058 VSYLEG-CYP--RCPKDRPIYEEDLKKCVTADKCGCYVEDTH----YPPGASVPTEETCK 1110
Query: 4748 NCTCVNES-LVCPHQECPVL-----GPWSAWSSCSAPCGGGTMERH 4787
+C C N S +VC +E +L G + W C GT+E+H
Sbjct: 1111 SCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGP---NGTVEKH 1153
Score = 33.9 bits (76), Expect = 4.3
Identities = 58/254 (22%), Positives = 87/254 (34%), Gaps = 73/254 (28%)
Query: 3528 DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC 3587
+C + CG +C+ S Q + C CP G ++ P C
Sbjct: 2221 ECPSHREYQACGPAEEPTCKSSSS----QQNNTVLVEGCFCPEGTMNY-----APGFDVC 2271
Query: 3588 QYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCV---AGIL----QCQEVP 3640
G +G P+N R G F C NC C+ +GI+ +C + P
Sbjct: 2272 VKTCGCVG-PDNVPREFGEHFEF------------DCKNCVCLEGGSGIICQPKRCSQKP 2318
Query: 3641 --DCPDPGVW--SSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCRE-- 3694
C + G + + P + C C C C+T +C+E
Sbjct: 2319 VTHCVEDGTYLATEVNPADTC--------------CNITVC--------KCNTSLCKEKP 2356
Query: 3695 AGCPAG-RLYRECQPGEGCPF-------SCAH--VTQQVG--CFSEGCEEGCHCPEGTFQ 3742
+ CP G + + PG CPF C H Q G +S C++ C C +
Sbjct: 2357 SVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQD-CVCTDKVDN 2415
Query: 3743 HRLACVQEC---PC 3753
+ L V C PC
Sbjct: 2416 NTLLNVIACTHVPC 2429
Score = 33.5 bits (75), Expect = 5.6
Identities = 29/122 (23%), Positives = 44/122 (36%), Gaps = 18/122 (14%)
Query: 3983 CPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAP 4042
C +++ R C C PGG D + SR CS GG P
Sbjct: 237 CQDLVPLEPYLRACQQDRCRCPGG----------DTCVCSTVAEFSRQCSHA----GGRP 282
Query: 4043 CAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPK 4102
G A CP + + + C CS L+ +C++ ++ GC CP+
Sbjct: 283 --GNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRM--DGCFCPE 338
Query: 4103 GS 4104
G+
Sbjct: 339 GA 340
Score = 33.5 bits (75), Expect = 5.6
Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 13/121 (10%)
Query: 3119 CHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTV--VRPCENCSCVSGLIAN 3173
C+P CP + CV C C E YPPG++V C++C C +
Sbjct: 1064 CYP--RCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVV 1121
Query: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTV---APLPLPATP 3230
C EG+ CGP F S + PST+ + LP TP
Sbjct: 1122 CRP---EEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTP 1178
Query: 3231 T 3231
T
Sbjct: 1179 T 1179
Score = 32.7 bits (73), Expect = 9.6
Identities = 26/95 (27%), Positives = 34/95 (35%), Gaps = 28/95 (29%)
Query: 3670 RRCARPPCPGPARQSRTCST-----QVCREAG--------------------CPAGRLYR 3704
R C + C P + CST + C AG CP +Y
Sbjct: 248 RACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYL 307
Query: 3705 ECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEG 3739
E G C +C+H+ C E +GC CPEG
Sbjct: 308 ES--GSPCMDTCSHLEVSSLC-EEHRMDGCFCPEG 339
Score = 32.7 bits (73), Expect = 9.6
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 9/81 (11%)
Query: 4942 QTCLEMNATKTQSNCSSARASGCV--CQPGH--FRSQAGPCVPEDHCECWHLGRPHLPGS 4997
+TC +N SN S + GC C + CV D C C+ + PG+
Sbjct: 1044 ETCRTINGI--HSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1101
Query: 4998 E--WQEACESCLCL-SGRPVC 5015
+E C+SC+C S + VC
Sbjct: 1102 SVPTEETCKSCVCTNSSQVVC 1122
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 409 bits (1051), Expect = e-113
Identities = 282/1030 (27%), Positives = 446/1030 (43%), Gaps = 103/1030 (10%)
Query: 394 CHQLLEGPFGQCHAQVSPA-EYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACAR 452
C++++ F +C + + +Y C+ YC Q + + C T++ + CA
Sbjct: 689 CNKIIGTYFEKCGKVAALSNDYKMICIDEYC--------QTRDKTSTCDTYSELSRLCAS 740
Query: 453 RH--IHIRWRKPG--FCE-RLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCEC 507
WR CE + CP +Y +C P +C V ++ ECVSGC C
Sbjct: 741 DGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTC 796
Query: 508 PRGLFWNGT----LCVPAAHCPCYYCRQRYVPGDTVRQLC-NPCVCRDGRWHCAQALCPA 562
P G + CV A CPC Y PG+ C + C C+D +W C +ALCP
Sbjct: 797 PEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPG 856
Query: 563 ECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVS 622
C V G TFDG Y+F G C + V + + L + G+CL+++++
Sbjct: 857 RCKVEGSS-LTTFDGVKYNFPGN--CHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLL 913
Query: 623 LEDT---HIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679
L + + +S + N + + ++ + + ASS++L + L P
Sbjct: 914 LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVP 973
Query: 680 VA--YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSE 737
V Y+++ P GLCG++ +DDF++ +E + AFA+ +++ CP
Sbjct: 974 VMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKG 1030
Query: 738 DSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSD 795
+ S C + ++ FAE C IL S CH +V+ +P++ C C C+ D
Sbjct: 1031 NP---SSCIS-IEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 796 CLCPVLSAYARRCAQ-EGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCG----KPEDC 850
CLC +L Y + CA+ E WR LC CP G ++ AC C + C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 851 GELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLW 910
V GC CP + + EG CV S C C + PG + N+C+C++ G+
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRD-GIL 1204
Query: 911 NC------TARHCPSQAFCPRELVYAPGACLLTCDSPSA----NHSCPAGSTD------- 953
C T ++C GA + C P A N +C +
Sbjct: 1205 LCQIPIDLTLQNCSG------------GAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLP 1252
Query: 954 ---GCVCPPGTVLLDER-CVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
GC CP G V + CV P+ CPC G+ Y + CN C C W CT
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNE 1312
Query: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLVRE----ASGLFTVSAQNLPCGASGLTCT 1065
C G H TFDG ++++ G C+Y + + +G F + +++PC GLTC+
Sbjct: 1313 CQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCS 1372
Query: 1066 KALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD 1125
+ + V + + + G+ V ++ S+ GL+L+L G+ ++WD
Sbjct: 1373 RKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNAN-AYSIHTVGLYLILKFQNGIIVIWD 1431
Query: 1126 GGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPG 1185
TR+ V L P + G+V GLCG+ +GD +D +R + A +SW+ S C +
Sbjct: 1432 KNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTV 1491
Query: 1186 DLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECL 1245
PC N + WA +C L F CH +V P +++ C+ +AC CD G
Sbjct: 1492 AQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1551
Query: 1246 CSAIATYADECARHGHHVRWRSQELCSLQCEGGQV-------YEACGPTCPPTCHEQHPE 1298
C+A+A YA+ C+ G V WR LC + C+ YE CG TC +Q
Sbjct: 1552 CTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG 1611
Query: 1299 PGWHCQVVACVEGCF--CPEGTLL---HGGACLEPASCPCEWGRNSFPPGSVLQKDCG-N 1352
+ + +EGC+ CP+ + C+ + C C + + P G V++ +CG
Sbjct: 1612 Q----KFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFY-NDVIPAGGVIEDNCGRT 1666
Query: 1353 CTCQEGQWHC 1362
C C GQ C
Sbjct: 1667 CYCIAGQLEC 1676
Score = 176 bits (446), Expect = 5e-43
Identities = 178/711 (25%), Positives = 269/711 (37%), Gaps = 95/711 (13%)
Query: 824 PVMCPG--GQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCP 881
P CP G+ Y C QHC K +G+ C L D + C+
Sbjct: 668 PGDCPNAVGKSYEVCEDGI-QHCNKI-----IGTYFEKCGKVAALSNDYKMICIDEY--- 718
Query: 882 CQLGARRYAPGSATMKECNRCICQERG-----LWN------CTARHCPSQAFCPRELVYA 930
CQ R T E +R +C G W C + CP Q
Sbjct: 719 CQ--TRDKTSTCDTYSELSR-LCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSN 775
Query: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD----ERCVPPDLCPCRHSGQWYLPN 986
P C +P + C GC CP G +L D +CV CPC SG Y P
Sbjct: 776 PATCSNV--APFQDSEC----VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG 829
Query: 987 ATIQEDC-NVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREAS 1045
+ C + C C+ +W CT GRC+ G+ TFDG+ + +PG C +L V
Sbjct: 830 EVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNED 888
Query: 1046 GLFTVSAQNLPCGASGLTCTKALAVRLEGTVV---HMLRGRAVTVNGVSVTPPKVYTGPG 1102
+V + P G +G TC ++ + L +V ++ N Y+
Sbjct: 889 WSISVELRPCPSGQTG-TCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKI 947
Query: 1103 LSLRRAGLFLLLST--HLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSR 1160
+ +L + T H+ L + ++ V + P GLCG ++ A +D S
Sbjct: 948 QIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007
Query: 1161 QGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTL--CHA 1218
Q +LE T++ A+SW + CP+ P C ++ + +A CG LL L CH
Sbjct: 1008 QNILEKTSQAFANSWEMMS-CPKGN--PSSC-ISIEKEKFAERHCGILLDSSGPLASCHP 1063
Query: 1219 EVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECA-RHGHHVRWRSQELCSLQCEG 1277
V P+ ++E C C C++ DC LC+ + Y CA + + V WR+ LC C
Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDC--LCTILGNYVKACAEKETYIVGWRTG-LCEHSCPS 1120
Query: 1278 GQVYEACGPTCPPTCHEQHPEPGWHCQVVAC-VEGCFCPEGTLLHG-GACLEPASCPCEW 1335
G V++ C +C E C V V+GC CP+ + G C+ + C C
Sbjct: 1121 GLVFKYNVKACNSSCRSLS-ERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179
Query: 1336 GRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWL 1395
PG ++ D C C++G LCQ +P
Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGI---------------------LLCQ-----IPIDLT 1213
Query: 1396 CDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQG 1455
N C G++ C+ P S +P+ D C G CP+G
Sbjct: 1214 LQN---CSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF---DENLPCKRGCF-----CPEG 1262
Query: 1456 LLACADGRCL-PPALLCD-GHPDCLDAADEESCLGQVTCVPGEVSCVDGTC 1504
++ + G C+ P C G + + + + TC+ G SC C
Sbjct: 1263 MVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313
Score = 137 bits (344), Expect = 4e-31
Identities = 133/509 (26%), Positives = 194/509 (38%), Gaps = 94/509 (18%)
Query: 84 PAKWNRTVRTCC-----------PGWGGAHCTEALAKASPEGHCFAMWQCQLQAGSANAS 132
P RT RTC P G C E + + S +G C C G
Sbjct: 1229 PKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNS-KGICVFPNDCPCSFGGREYD 1287
Query: 133 AGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPS 192
GS+ +S C C+ + GS WS Q
Sbjct: 1288 EGSV---------------TSVGCNECTC--IKGS-----------------WSCTQNEC 1313
Query: 193 AT-CASWSGFHYRTFDGRHYHFLGRCTYLL----AGAADSTWAVHLTPGDRCPQPG-HCQ 246
T C + H RTFDG+ Y F G C Y G + T+ + LT C + G C
Sbjct: 1314 QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRI-LTESVPCCEDGLTCS 1372
Query: 247 R---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDR 303
R V + +++Q G V+ + + S+ +G +L+L G++V D+
Sbjct: 1373 RKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDK 1432
Query: 304 TGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLD 363
+S+ +D G+ GLCG NG +DDF +A A FGNSW+ + C D
Sbjct: 1433 NTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSD 1489
Query: 364 AVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
V CD + +A A C L + F CH +V P+ YH+ C+ C
Sbjct: 1490 TVAQTFPCD---------SNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC 1540
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCP 483
A M EG+ C A Y +AC+ + + WRKP C C Y + C
Sbjct: 1541 ACDM-----EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD----YYNAPGECR 1591
Query: 484 PSCEAVGQGEEESCREECV--------SGC--ECPRG---LFWNGTLCVPAAHCPCYYCR 530
E G ++C+++ V GC +CP L N CV + C C+Y
Sbjct: 1592 WHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFY-- 1649
Query: 531 QRYVP-GDTVRQLC-NPCVCRDGRWHCAQ 557
+P G + C C C G+ C++
Sbjct: 1650 NDVIPAGGVIEDNCGRTCYCIAGQLECSE 1678
Score = 126 bits (317), Expect = 5e-28
Identities = 104/372 (27%), Positives = 150/372 (40%), Gaps = 43/372 (11%)
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP--QPGHC-QRVTM------ 250
G TFDG Y+F G C +L D + +V L P CP Q G C VT+
Sbjct: 862 GSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVELRP---CPSGQTGTCLNSVTLLLNSSV 918
Query: 251 GPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG--SIS 308
++ + + ++ +G + +L + V +++ +
Sbjct: 919 PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978
Query: 309 ISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVA 368
+S+ + T GLCG YN EDDFM L + F NSW + G
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-------- 1030
Query: 369 QGCDPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGA 426
+P I + E A+ C LL+ GP CH V+P YHE C C
Sbjct: 1031 ---NPSSCISIEKE-----KFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCT-- 1080
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPSC 486
E Q +C +YV+ACA + +I + G CE CP G ++ V C SC
Sbjct: 1081 -----CENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSC 1135
Query: 487 EAVGQGEEESCREE--CVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQLC 543
++ + + SC E V GC CP ++ N CV + C CY + PG +
Sbjct: 1136 RSLSE-RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD 1194
Query: 544 NPCVCRDGRWHC 555
N CVCRDG C
Sbjct: 1195 NKCVCRDGILLC 1206
Score = 72.4 bits (176), Expect = 1e-11
Identities = 61/225 (27%), Positives = 86/225 (38%), Gaps = 34/225 (15%)
Query: 4818 CPPGQVLSACATSCPCLCWHL--QPGAICVQEPCQPGCGCPGGQLLHN-GTCVPPTACPC 4874
CP G V +C C L + + V++ GC CP +N G CV + C C
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 1177
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAP 4934
+ + + PG ++ + +CVC G ++ CQ+P T Q +
Sbjct: 1178 YIND-------------EVMQPGKLIHIDDNKCVCRDG-----ILLCQIPIDLTLQNCSG 1219
Query: 4935 G-ELGLCE---------QTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHC 4984
G E C +TC N N R GC C G R+ G CV + C
Sbjct: 1220 GAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKR--GCFCPEGMVRNSKGICVFPNDC 1277
Query: 4985 ECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH-CSPLTCAQGE 5028
C GR + GS C C C+ G CTQ+ C + GE
Sbjct: 1278 PCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGE 1322
Score = 65.1 bits (157), Expect = 2e-09
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 21/148 (14%)
Query: 2851 QTRGRS--CSSLAPGDTTC----PGPHSQTRDCNTQPC-TAQCPENMLFRSAEQCHQEGG 2903
QTR ++ C + + C PG R + C T +CPE +++ E G
Sbjct: 720 QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYK-------ECG 772
Query: 2904 PC-PRLCLTQGPGIECTGFCAPGCTCPPGLFLHN----ASCLPRSQCPCQLHGQLYASGA 2958
P P C P + C GCTCP G L + C+ +++CPC+ G +Y G
Sbjct: 773 PSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ + CTC K +CT CP C
Sbjct: 831 VREGPCGSQCTCQDAKWSCTEALCPGRC 858
Score = 62.8 bits (151), Expect = 9e-09
Identities = 54/203 (26%), Positives = 78/203 (38%), Gaps = 23/203 (11%)
Query: 1761 VCSEPCRGTMTRQRQCHSPQNGGRTCAAL-PGGLHSTRQTKPCPQDGCPNATCSGELMFQ 1819
+C + T + C + R CA+ PG S R C C + +++
Sbjct: 713 ICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV---CETQRCPEQHIYK 769
Query: 1820 PCAPC-PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVL---GSEGWCVWPRQCPCLVDGA 1875
C P P TC +++ D C S GC CPEG +L G +G CV +CPC G
Sbjct: 770 ECGPSNPATCSNVAPF----QDSECVS-GCTCPEGYLLDDIGEKGKCVLKAECPCESSGT 824
Query: 1876 RYWPGQRIKADC-QLCICQDGR--------PRRCRLNPDCAVDCGWSSWSPWAKCLGPCG 1926
Y PG+ + C C CQD + P RC++ ++ C
Sbjct: 825 VYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNFPGNC-HFLA 883
Query: 1927 SQSIQWSFRSSNNPRPSGRGRQC 1949
+ WS P PSG+ C
Sbjct: 884 VHNEDWSISVELRPCPSGQTGTC 906
Score = 60.8 bits (146), Expect = 3e-08
Identities = 67/277 (24%), Positives = 103/277 (37%), Gaps = 74/277 (26%)
Query: 4682 CPHSCADLWDRVQCLQGPCRP--GCRCPPGQLVQ-DGRCVPISSCRCGLPSANASWELAP 4738
C SC L +R + P GC CP +G CV S C C + + P
Sbjct: 1131 CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDE----VMQP 1186
Query: 4739 AQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+ + +D C C + L+C + P+ T++ C GG
Sbjct: 1187 GKLIHIDDNKCVCRDGILLC---QIPI---------------DLTLQ---NCSGGAEYVD 1225
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACAT-SCPCLCWHLQPGAICVQEPCQPGCGCPG 4857
C ++R C+T + P +L PC+ GC CP
Sbjct: 1226 CSDPKAQRRTN---------------RTCSTRNIPVFDENL---------PCKRGCFCPE 1261
Query: 4858 GQLLHN-GTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
G + ++ G CV P CPC+ +G +E G+V + C C C G++SC
Sbjct: 1262 GMVRNSKGICVFPNDCPCS-----FG--------GREYDEGSVTSVGCNECTCIKGSWSC 1308
Query: 4917 SLVDCQV---PPGETWQQVAPGEL----GLCEQTCLE 4946
+ +CQ GE + G+ GLC+ + LE
Sbjct: 1309 TQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLE 1345
Score = 60.8 bits (146), Expect = 3e-08
Identities = 40/115 (34%), Positives = 54/115 (46%), Gaps = 15/115 (13%)
Query: 3300 VCQALPCPVTNCTAIEGAEYSPCGPP-----CPRSCDDLVHCVWR----CQPGCYCPPGQ 3350
+CQ +P +T GAEY C P R+C V+ C+ GC+CP G
Sbjct: 1205 LCQ-IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGM 1263
Query: 3351 VLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
V +S G ICV P C C G+ + G+ GCN CTC++G +CT C
Sbjct: 1264 VRNSKG-ICVFPNDCPCS--FGGREYDEGS--VTSVGCNECTCIKGSWSCTQNEC 1313
Score = 60.5 bits (145), Expect = 4e-08
Identities = 53/217 (24%), Positives = 87/217 (40%), Gaps = 27/217 (12%)
Query: 4317 GPCSRSCGPGLASR------SGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSS 4370
G C SC GL + + SC L ++ D +C+ + +D GC CP+ ++
Sbjct: 1112 GLCEHSCPSGLVFKYNVKACNSSCRSL-SERDRSCDVEDVPVD--GC---TCPDAMYQNN 1165
Query: 4371 WSSWT-RCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEF 4429
+ + C + G C DG + + + +C+ E+
Sbjct: 1166 EGNCVLKSQCDCYINDEVMQPGKLIH--IDDNKCVCRDGILLCQIPIDLTLQNCSGGAEY 1223
Query: 4430 HACGSPCAG-----LCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGG-CIPPEECNCWHT 4483
C P A C+T ++LP C+ GC+CP+G++ + G C+ P +C C
Sbjct: 1224 VDCSDPKAQRRTNRTCSTRNIPVFDENLP-CKRGCFCPEGMVRNSKGICVFPNDCPC--- 1279
Query: 4484 SAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ 4520
+ G G +GC EC C +G CT CQ
Sbjct: 1280 --SFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQ 1314
Score = 60.5 bits (145), Expect = 4e-08
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 23/110 (20%)
Query: 3091 PRDKQWLDCAQGP--ASCAELSAPRGTNQTCHP--------------GCHCPSGMLLLNN 3134
P D +C+ G C++ A R TN+TC GC CP GM+ +
Sbjct: 1209 PIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSK 1268
Query: 3135 -VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGE 3183
+CV DCPC+ G Y GS C C+C+ G SW C + E
Sbjct: 1269 GICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKG------SWSCTQNE 1312
Score = 57.8 bits (138), Expect = 3e-07
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 2922 CAPGCTCPPGLFLHNAS-CLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSE 2980
C GC CP G+ ++ C+ + CPC G+ Y G++ + CN CTC+ G +CT
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSV-GCNECTCIKGSWSCTQN 1311
Query: 2981 RCPVAC 2986
C C
Sbjct: 1312 ECQTIC 1317
Score = 57.4 bits (137), Expect = 4e-07
Identities = 79/350 (22%), Positives = 114/350 (32%), Gaps = 113/350 (32%)
Query: 3479 GPWSPCDMCLGQSHRSRACSRPP-TPEGGRPCP----GNHTQSRPCQENSTQCTDCGGGQ 3533
GP + C + C + T E + C GN+ ++ C E T G
Sbjct: 1056 GPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKA--CAEKETYIVGWRTGL 1113
Query: 3534 SLHPCG---------QPCPRSCQDLSPGS-VCQPGSVGCQPTCGCPLGQL-SQDGLCVPP 3582
H C + C SC+ LS C V C CP + +G CV
Sbjct: 1114 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-CTCPDAMYQNNEGNCVLK 1172
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDC 3642
+ C C + + E ++PG+++ + C C GIL CQ D
Sbjct: 1173 SQCDC--------------------YINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDL 1212
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRL 3702
++CS GG E + C+ P R +RTCST+
Sbjct: 1213 T----------LQNCS---GGAEYVD---CSDPKAQ--RRTNRTCSTR------------ 1242
Query: 3703 YRECQPGEGCPFSCAHVTQQVGCFSEG--CEEGCHCPEGTFQHRLA-CV--QECPCVLTA 3757
+ F E C+ GC CPEG ++ CV +CPC
Sbjct: 1243 -------------------NIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFG- 1282
Query: 3758 WLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
G E D G C C+C G SC+ ++C
Sbjct: 1283 -------------------GREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313
Score = 56.2 bits (134), Expect = 8e-07
Identities = 55/208 (26%), Positives = 69/208 (33%), Gaps = 37/208 (17%)
Query: 1713 WGQGRSRRCSPLGLLVLQN-------CPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEP 1765
W G P GL+ N C + ++C PVDG C +
Sbjct: 1109 WRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG--------CTCPDA 1160
Query: 1766 C----RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC 1821
G + QC N PG L K +DG +L Q C
Sbjct: 1161 MYQNNEGNCVLKSQCDCYINDE---VMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNC 1217
Query: 1822 APCP--LTCDDISGQV----TCPP--------DWPCGSPGCWCPEGQVLGSEGWCVWPRQ 1867
+ + C D Q TC + PC GC+CPEG V S+G CV+P
Sbjct: 1218 SGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPC-KRGCFCPEGMVRNSKGICVFPND 1276
Query: 1868 CPCLVDGARYWPGQRIKADCQLCICQDG 1895
CPC G Y G C C C G
Sbjct: 1277 CPCSFGGREYDEGSVTSVGCNECTCIKG 1304
Score = 55.5 bits (132), Expect = 1e-06
Identities = 34/104 (32%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 4062 CPAGMEVVTCAN-----RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGG-CVPIG 4115
C G E V C++ R R CS + V ++ C++GC CP+G + G CV
Sbjct: 1217 CSGGAEYVDCSDPKAQRRTNRTCST-RNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPN 1275
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTH 4159
C C+ G + GS CN C+C G SCT C H
Sbjct: 1276 DCPCSFG-GREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318
Score = 54.7 bits (130), Expect = 2e-06
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 13/110 (11%)
Query: 3300 VCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCV-WRCQPGCYCPPGQVLSSNG-- 3356
VC+ CP E Y CGP P +C ++ C GC CP G +L G
Sbjct: 756 VCETQRCP-------EQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEK 808
Query: 3357 AICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
CV C C +G + PG P G + CTC + + +CT+ CP
Sbjct: 809 GKCVLKAECPCES--SGTVYQPGEVREGPCG-SQCTCQDAKWSCTEALCP 855
Score = 53.5 bits (127), Expect = 5e-06
Identities = 44/137 (32%), Positives = 59/137 (43%), Gaps = 23/137 (16%)
Query: 3669 SRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSE 3728
SR CA PG R+ S VC CP +Y+EC P P +C++V F +
Sbjct: 735 SRLCASDG-PGTFESWRSDSDVVCETQRCPEQHIYKECGPSN--PATCSNVAP----FQD 787
Query: 3729 G-CEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLR 3787
C GC CPEG + ++ CVL A E T+ PG E+ G
Sbjct: 788 SECVSGCTCPEGYLLDDIG--EKGKCVLKAECPCESSGTVYQPG-------EVREG---- 834
Query: 3788 TSCGN-CSCAHGKLSCS 3803
CG+ C+C K SC+
Sbjct: 835 -PCGSQCTCQDAKWSCT 850
Score = 53.5 bits (127), Expect = 5e-06
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 10/99 (10%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD----GGCVPIGHC 4117
CP C P CS+ + D C GC CP+G L D G CV C
Sbjct: 762 CPEQHIYKECGPSNPATCSN----VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAEC 817
Query: 4118 DCTDAQGHSWAPGSQHQDAC-NNCSCQAGQLSCTAQPCP 4155
C ++ G + PG + C + C+CQ + SCT CP
Sbjct: 818 PC-ESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCP 855
Score = 52.4 bits (124), Expect = 1e-05
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 14/98 (14%)
Query: 3090 CPRDKQWLDCA-QGPASCAELSAPRGTNQTCHPGCHCPSGMLLLN----NVCVPTQDCPC 3144
CP + +C PA+C+ ++ + + C GC CP G LL + CV +CPC
Sbjct: 762 CPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPC 819
Query: 3145 AHEGHLYPPGSTVVRPC-ENCSCVSGLIANCSSWPCAE 3181
G +Y PG PC C+C + W C E
Sbjct: 820 ESSGTVYQPGEVREGPCGSQCTCQD------AKWSCTE 851
Score = 51.6 bits (122), Expect = 2e-05
Identities = 51/209 (24%), Positives = 67/209 (32%), Gaps = 25/209 (11%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQE-GIVCQDDQVCQKGCRCPKGSLE-QDGGCVPIG 4115
CE CP+G+ C C L E C + V GC CP + +G CV
Sbjct: 1114 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 1173
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSC 4175
CDC PG N C C+ G L C P + S +
Sbjct: 1174 QCDCY-INDEVMQPGKLIHIDDNKCVCRDGILLCQI-----PIDLTLQNCSGGAEYVDCS 1227
Query: 4176 GPRGQQSRFRSSTS--------------GSWAPECREEQSQSQPCPQPSCPPLCLQGTRS 4221
P+ Q+ R+ ++ G + PE S+ CP C G R
Sbjct: 1228 DPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCP--CSFGGRE 1285
Query: 4222 RTLGDSWLQGECQRCSCTPEGVICEDTEC 4250
G G C C+C C EC
Sbjct: 1286 YDEGSVTSVG-CNECTCIKGSWSCTQNEC 1313
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/143 (28%), Positives = 50/143 (34%), Gaps = 27/143 (18%)
Query: 4785 ERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAI 4843
E R C GPG D++ C Q CPE + C S P C ++ P
Sbjct: 733 ELSRLCASDGPGTFESWRSDSDV--VCETQRCPE---QHIYKECGPSNPATCSNVAPFQ- 786
Query: 4844 CVQEPCQPGCGCPGGQLL----HNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTV 4899
C GC CP G LL G CV CPC E PG V
Sbjct: 787 --DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPC-------------ESSGTVYQPGEV 831
Query: 4900 LTRNC-TRCVCHGGAFSCSLVDC 4921
C ++C C +SC+ C
Sbjct: 832 REGPCGSQCTCQDAKWSCTEALC 854
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/70 (38%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 2652 CVEGCRCPPGLLLHDT----RCLPLSECPCLVGEELKWPGVSFLLGNC-SQCVCEKGELL 2706
CV GC CP G LL D +C+ +ECPC + PG G C SQC C+ +
Sbjct: 790 CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG-EVREGPCGSQCTCQDAKWS 848
Query: 2707 CQPGGCPLPC 2716
C CP C
Sbjct: 849 CTEALCPGRC 858
Score = 47.8 bits (112), Expect = 3e-04
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFR-SAEQCHQEGGPCPRLCLTQGPG 2915
C+ L C + T C CP ++F+ + + C+ C L +
Sbjct: 1089 CTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS---CRSLS-ERDRS 1144
Query: 2916 IECTGFCAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGK 2974
+ GCTCP ++ +N +C+ +SQC C ++ ++ G + +D N C C G
Sbjct: 1145 CDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD-NKCVCRDGI 1203
Query: 2975 MAC 2977
+ C
Sbjct: 1204 LLC 1206
Score = 47.8 bits (112), Expect = 3e-04
Identities = 38/126 (30%), Positives = 49/126 (38%), Gaps = 37/126 (29%)
Query: 2606 LQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKA----NRSCSGH---------- 2651
LQ CSGG + YV C DPKA NR+CS
Sbjct: 1214 LQNCSGGAE------YVD---------------CSDPKAQRRTNRTCSTRNIPVFDENLP 1252
Query: 2652 CVEGCRCPPGLLLHDTR-CLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG 2710
C GC CP G++ + C+ ++CPC G G +G C++C C KG C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG-CNECTCIKGSWSCTQN 1311
Query: 2711 GCPLPC 2716
C C
Sbjct: 1312 ECQTIC 1317
Score = 47.0 bits (110), Expect = 5e-04
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 2627 CQKGLV-----PPCPPSCLD-PKANRSCSGHCV--EGCRCPPGLLLHDT-RCLPLSECPC 2677
C GLV C SC + +RSC V +GC CP + ++ C+ S+C C
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 1177
Query: 2678 LVGEELKWPGVSFLLGNCSQCVCEKGELLCQ 2708
+ +E+ PG + + ++CVC G LLCQ
Sbjct: 1178 YINDEVMQPGKLIHIDD-NKCVCRDGILLCQ 1207
Score = 45.1 bits (105), Expect = 0.002
Identities = 36/137 (26%), Positives = 51/137 (37%), Gaps = 23/137 (16%)
Query: 4639 WREAEALC---GGGCREPWAQES---CNGGPCPECEAQDTVFTLDCANQCPHSCADLWDR 4692
+ E LC G G E W +S C CPE +C P +C+++
Sbjct: 731 YSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYK-----ECGPSNPATCSNV--- 782
Query: 4693 VQCLQGPCRPGCRCPPGQLVQD----GRCVPISSCRCGLPSANASWELAPAQAVQLDC-Q 4747
C GC CP G L+ D G+CV + C C ++ P + + C
Sbjct: 783 APFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPC----ESSGTVYQPGEVREGPCGS 838
Query: 4748 NCTCVNESLVCPHQECP 4764
CTC + C CP
Sbjct: 839 QCTCQDAKWSCTEALCP 855
Score = 43.9 bits (102), Expect = 0.004
Identities = 38/139 (27%), Positives = 47/139 (33%), Gaps = 31/139 (22%)
Query: 3510 PGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCP 3569
PG R + + C CG P +C +++P + C C CP
Sbjct: 743 PGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDSE-----CVSGCTCP 797
Query: 3570 LGQLSQD----GLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPC- 3624
G L D G CV A C C+ SS +PGEV GPC
Sbjct: 798 EGYLLDDIGEKGKCVLKAECPCE--------------------SSGTVYQPGEVREGPCG 837
Query: 3625 DNCTCVAGILQCQEVPDCP 3643
CTC C E CP
Sbjct: 838 SQCTCQDAKWSCTEAL-CP 855
Score = 42.7 bits (99), Expect = 0.009
Identities = 28/109 (25%), Positives = 40/109 (36%), Gaps = 14/109 (12%)
Query: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLL----EQAGGCI 4473
C C + CG C+ Q + C GC CP+G L + G C+
Sbjct: 757 CETQRCPEQHIYKECGPSNPATCSNVAPFQDSE----CVSGCTCPEGYLLDDIGEKGKCV 812
Query: 4474 PPEECNCWHTSAAGAGMTLAPGDRLQLGC-KECECRRGELHCTSQGCQG 4521
EC C +G PG+ + C +C C+ + CT C G
Sbjct: 813 LKAECPC-----ESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPG 856
Score = 38.1 bits (87), Expect = 0.23
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 4/67 (5%)
Query: 4962 SGCVCQPGHFRS---QAGPCVPEDHCECWHLGRPHLPGSEWQEACES-CLCLSGRPVCTQ 5017
SGC C G+ + G CV + C C G + PG + C S C C + CT+
Sbjct: 792 SGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTE 851
Query: 5018 HCSPLTC 5024
P C
Sbjct: 852 ALCPGRC 858
Score = 35.0 bits (79), Expect = 1.9
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 9/76 (11%)
Query: 2638 SCLDPKANRSCSGHCVEGC--RCP---PGLLLHDTRCLPLSECPCLVGEELKWPGVSFLL 2692
+C D + S +EGC +CP P L + +C+ LSEC C + + GV +
Sbjct: 1604 TCKDQLVGQKFSS-LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGV--IE 1660
Query: 2693 GNCSQ-CVCEKGELLC 2707
NC + C C G+L C
Sbjct: 1661 DNCGRTCYCIAGQLEC 1676
Score = 34.3 bits (77), Expect = 3.3
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 13/91 (14%)
Query: 3319 YSPCGPPCPRSCDDLV--HCVWRCQPGCY--CP-PGQVLSSNGAICVQPGHCSCL--DLL 3371
Y PCG ++C D + GCY CP L N CV CSC D++
Sbjct: 1594 YEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI 1653
Query: 3372 TGQRHHPGARLARPDGCNHCTCLEGRLNCTD 3402
P + + C C+ G+L C++
Sbjct: 1654 ------PAGGVIEDNCGRTCYCIAGQLECSE 1678
Score = 34.3 bits (77), Expect = 3.3
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 23/104 (22%)
Query: 3537 PCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGL-CVPPAHCRCQYQPGAMG 3595
PCG ++C+D G GC C L ++ + CV + C C Y
Sbjct: 1596 PCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYN----- 1650
Query: 3596 IPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTCVAGILQCQE 3638
+ + G V+ C C C+AG L+C E
Sbjct: 1651 ----------------DVIPAGGVIEDNCGRTCYCIAGQLECSE 1678
Score = 33.9 bits (76), Expect = 4.3
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCY--CPKG---LLEQAGGCIPPEECNCW 4481
+ + CG+ A C L Q L GCY CP L E C+ EC+C+
Sbjct: 1592 WHYEPCGTVTAKTCKDQLVGQKFSSL---LEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648
Query: 4482 HTSAAGAGMTLAPGDRLQLGC-KECECRRGELHCT 4515
+ AG ++ C + C C G+L C+
Sbjct: 1649 YNDVIPAGGV------IEDNCGRTCYCIAGQLECS 1677
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 407 bits (1045), Expect = e-112
Identities = 281/1030 (27%), Positives = 445/1030 (43%), Gaps = 103/1030 (10%)
Query: 394 CHQLLEGPFGQCHAQVSPA-EYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACAR 452
C++++ F +C + + +Y C+ YC Q + + C T++ + CA
Sbjct: 689 CNKIIGTYFEKCGKVAALSNDYKMICIDEYC--------QTRDKTSTCDTYSELSRLCAS 740
Query: 453 RH--IHIRWRKPG--FC-ERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCEC 507
WR C + CP +Y +C P +C V ++ ECVSGC C
Sbjct: 741 DGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTC 796
Query: 508 PRGLFWNGT----LCVPAAHCPCYYCRQRYVPGDTVRQLC-NPCVCRDGRWHCAQALCPA 562
P G + CV A CPC Y PG+ C + C C+D +W C +ALCP
Sbjct: 797 PEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPG 856
Query: 563 ECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVS 622
C V G TFDG Y+F G C + V + + L + G+CL+++++
Sbjct: 857 RCKVEGSS-LTTFDGVKYNFPGN--CHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLL 913
Query: 623 LEDT---HIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679
L + + +S + N + + ++ + + ASS++L + L P
Sbjct: 914 LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVP 973
Query: 680 VA--YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSE 737
V Y+++ P GLCG++ +DDF++ +E + AFA+ +++ CP
Sbjct: 974 VMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKG 1030
Query: 738 DSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSD 795
+ S C + ++ FAE C IL S CH +V+ +P++ C C C+ D
Sbjct: 1031 NP---SSCIS-IEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 796 CLCPVLSAYARRCAQ-EGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCG----KPEDC 850
CLC +L Y + CA+ E WR LC CP G ++ AC C + C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 851 GELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLW 910
V GC CP + + EG CV S C C + PG + N+C+C++ G+
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRD-GIL 1204
Query: 911 NC------TARHCPSQAFCPRELVYAPGACLLTCDSPSA----NHSCPAGSTD------- 953
C T ++C GA + C P A N +C +
Sbjct: 1205 LCQIPIDLTLQNCSG------------GAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLP 1252
Query: 954 ---GCVCPPGTVLLDER-CVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
GC CP G V + CV P+ CPC G+ Y + CN C C W CT
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNE 1312
Query: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLVRE----ASGLFTVSAQNLPCGASGLTCT 1065
C G H TFDG ++++ G C+Y + + +G F + +++PC GLTC+
Sbjct: 1313 CQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCS 1372
Query: 1066 KALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWD 1125
+ + V + + + G+ V ++ S+ GL+L+L G+ ++WD
Sbjct: 1373 RKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNAN-AYSIHTVGLYLILKFQNGIIVIWD 1431
Query: 1126 GGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPG 1185
TR+ V L P + G+V GLCG+ +GD +D +R + A +SW+ S C +
Sbjct: 1432 KNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTV 1491
Query: 1186 DLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECL 1245
PC N + WA +C L F CH +V P +++ C+ +AC CD G
Sbjct: 1492 AQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1551
Query: 1246 CSAIATYADECARHGHHVRWRSQELCSLQCEGGQV-------YEACGPTCPPTCHEQHPE 1298
C+A+A YA+ C+ G V WR LC + C+ YE CG TC +Q
Sbjct: 1552 CTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG 1611
Query: 1299 PGWHCQVVACVEGCF--CPEGTLL---HGGACLEPASCPCEWGRNSFPPGSVLQKDCG-N 1352
+ + +EGC+ CP+ + C+ + C C + + P G V++ +CG
Sbjct: 1612 Q----KFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFY-NDVIPAGGVIEDNCGRT 1666
Query: 1353 CTCQEGQWHC 1362
C C GQ C
Sbjct: 1667 CYCIAGQLEC 1676
Score = 176 bits (445), Expect = 7e-43
Identities = 178/711 (25%), Positives = 269/711 (37%), Gaps = 95/711 (13%)
Query: 824 PVMCPG--GQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCP 881
P CP G+ Y C QHC K +G+ C L D + C+
Sbjct: 668 PGDCPNAVGKSYEVCEDGI-QHCNKI-----IGTYFEKCGKVAALSNDYKMICIDEY--- 718
Query: 882 CQLGARRYAPGSATMKECNRCICQERG-----LWN------CTARHCPSQAFCPRELVYA 930
CQ R T E +R +C G W C + CP Q
Sbjct: 719 CQ--TRDKTSTCDTYSELSR-LCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSN 775
Query: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD----ERCVPPDLCPCRHSGQWYLPN 986
P C +P + C GC CP G +L D +CV CPC SG Y P
Sbjct: 776 PATCSNV--APFQDSEC----VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG 829
Query: 987 ATIQEDC-NVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREAS 1045
+ C + C C+ +W CT GRC+ G+ TFDG+ + +PG C +L V
Sbjct: 830 EVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNED 888
Query: 1046 GLFTVSAQNLPCGASGLTCTKALAVRLEGTVV---HMLRGRAVTVNGVSVTPPKVYTGPG 1102
+V + P G +G TC ++ + L +V ++ N Y+
Sbjct: 889 WSISVELRPCPSGQTG-TCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKI 947
Query: 1103 LSLRRAGLFLLLST--HLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSR 1160
+ +L + T H+ L + ++ V + P GLCG ++ A +D S
Sbjct: 948 QIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007
Query: 1161 QGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTL--CHA 1218
Q +LE T++ A+SW + CP+ P C ++ + +A CG LL L CH
Sbjct: 1008 QNILEKTSQAFANSWEMMS-CPKGN--PSSC-ISIEKEKFAERHCGILLDSSGPLASCHP 1063
Query: 1219 EVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECA-RHGHHVRWRSQELCSLQCEG 1277
V P+ ++E C C C++ DC LC+ + Y CA + + V WR+ LC C
Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDC--LCTILGNYVKACAEKETYIVGWRTG-LCEHSCPS 1120
Query: 1278 GQVYEACGPTCPPTCHEQHPEPGWHCQVVAC-VEGCFCPEGTLLHG-GACLEPASCPCEW 1335
G V++ C +C E C V V+GC CP+ + G C+ + C C
Sbjct: 1121 GLVFKYNVKACNSSCRSLS-ERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179
Query: 1336 GRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWL 1395
PG ++ D C C++G LCQ +P
Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGI---------------------LLCQ-----IPIDLT 1213
Query: 1396 CDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQG 1455
N C G++ C+ P S +P+ D C G CP+G
Sbjct: 1214 LQN---CSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF---DENLPCKRGCF-----CPEG 1262
Query: 1456 LLACADGRCL-PPALLCD-GHPDCLDAADEESCLGQVTCVPGEVSCVDGTC 1504
++ + G C+ P C G + + + + TC+ G SC C
Sbjct: 1263 MVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313
Score = 137 bits (344), Expect = 4e-31
Identities = 133/509 (26%), Positives = 194/509 (38%), Gaps = 94/509 (18%)
Query: 84 PAKWNRTVRTCC-----------PGWGGAHCTEALAKASPEGHCFAMWQCQLQAGSANAS 132
P RT RTC P G C E + + S +G C C G
Sbjct: 1229 PKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNS-KGICVFPNDCPCSFGGREYD 1287
Query: 133 AGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWSQHQRPS 192
GS+ +S C C+ + GS WS Q
Sbjct: 1288 EGSV---------------TSVGCNECTC--IKGS-----------------WSCTQNEC 1313
Query: 193 AT-CASWSGFHYRTFDGRHYHFLGRCTYLL----AGAADSTWAVHLTPGDRCPQPG-HCQ 246
T C + H RTFDG+ Y F G C Y G + T+ + LT C + G C
Sbjct: 1314 QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRI-LTESVPCCEDGLTCS 1372
Query: 247 R---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDR 303
R V + +++Q G V+ + + S+ +G +L+L G++V D+
Sbjct: 1373 RKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDK 1432
Query: 304 TGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLD 363
+S+ +D G+ GLCG NG +DDF +A A FGNSW+ + C D
Sbjct: 1433 NTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSD 1489
Query: 364 AVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
V CD + +A A C L + F CH +V P+ YH+ C+ C
Sbjct: 1490 TVAQTFPCD---------SNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC 1540
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCP 483
A M EG+ C A Y +AC+ + + WRKP C C Y + C
Sbjct: 1541 ACDM-----EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD----YYNAPGECR 1591
Query: 484 PSCEAVGQGEEESCREECV--------SGC--ECPRG---LFWNGTLCVPAAHCPCYYCR 530
E G ++C+++ V GC +CP L N CV + C C+Y
Sbjct: 1592 WHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFY-- 1649
Query: 531 QRYVP-GDTVRQLC-NPCVCRDGRWHCAQ 557
+P G + C C C G+ C++
Sbjct: 1650 NDVIPAGGVIEDNCGRTCYCIAGQLECSE 1678
Score = 126 bits (317), Expect = 5e-28
Identities = 104/372 (27%), Positives = 150/372 (40%), Gaps = 43/372 (11%)
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP--QPGHC-QRVTM------ 250
G TFDG Y+F G C +L D + +V L P CP Q G C VT+
Sbjct: 862 GSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVELRP---CPSGQTGTCLNSVTLLLNSSV 918
Query: 251 GPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG--SIS 308
++ + + ++ +G + +L + V +++ +
Sbjct: 919 PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978
Query: 309 ISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVA 368
+S+ + T GLCG YN EDDFM L + F NSW + G
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-------- 1030
Query: 369 QGCDPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGA 426
+P I + E A+ C LL+ GP CH V+P YHE C C
Sbjct: 1031 ---NPSSCISIEKE-----KFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCT-- 1080
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPSC 486
E Q +C +YV+ACA + +I + G CE CP G ++ V C SC
Sbjct: 1081 -----CENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSC 1135
Query: 487 EAVGQGEEESCREE--CVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQLC 543
++ + + SC E V GC CP ++ N CV + C CY + PG +
Sbjct: 1136 RSLSE-RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD 1194
Query: 544 NPCVCRDGRWHC 555
N CVCRDG C
Sbjct: 1195 NKCVCRDGILLC 1206
Score = 72.4 bits (176), Expect = 1e-11
Identities = 61/225 (27%), Positives = 86/225 (38%), Gaps = 34/225 (15%)
Query: 4818 CPPGQVLSACATSCPCLCWHL--QPGAICVQEPCQPGCGCPGGQLLHN-GTCVPPTACPC 4874
CP G V +C C L + + V++ GC CP +N G CV + C C
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 1177
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAP 4934
+ + + PG ++ + +CVC G ++ CQ+P T Q +
Sbjct: 1178 YIND-------------EVMQPGKLIHIDDNKCVCRDG-----ILLCQIPIDLTLQNCSG 1219
Query: 4935 G-ELGLCE---------QTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHC 4984
G E C +TC N N R GC C G R+ G CV + C
Sbjct: 1220 GAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKR--GCFCPEGMVRNSKGICVFPNDC 1277
Query: 4985 ECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH-CSPLTCAQGE 5028
C GR + GS C C C+ G CTQ+ C + GE
Sbjct: 1278 PCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGE 1322
Score = 65.1 bits (157), Expect = 2e-09
Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 19/137 (13%)
Query: 2855 RSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPC-PRLCLTQG 2913
R C+S PG S D + T +CPE +++ E GP P C
Sbjct: 736 RLCASDGPGTF-----ESWRSDSDVVCGTQRCPEQHIYK-------ECGPSNPATCSNVA 783
Query: 2914 PGIECTGFCAPGCTCPPGLFLHN----ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCT 2969
P + C GCTCP G L + C+ +++CPC+ G +Y G + + CT
Sbjct: 784 PFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCT 841
Query: 2970 CVSGKMACTSERCPVAC 2986
C K +CT CP C
Sbjct: 842 CQDAKWSCTEALCPGRC 858
Score = 62.4 bits (150), Expect = 1e-08
Identities = 54/203 (26%), Positives = 78/203 (38%), Gaps = 23/203 (11%)
Query: 1761 VCSEPCRGTMTRQRQCHSPQNGGRTCAAL-PGGLHSTRQTKPCPQDGCPNATCSGELMFQ 1819
+C + T + C + R CA+ PG S R C C + +++
Sbjct: 713 ICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV---CGTQRCPEQHIYK 769
Query: 1820 PCAPC-PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVL---GSEGWCVWPRQCPCLVDGA 1875
C P P TC +++ D C S GC CPEG +L G +G CV +CPC G
Sbjct: 770 ECGPSNPATCSNVAPF----QDSECVS-GCTCPEGYLLDDIGEKGKCVLKAECPCESSGT 824
Query: 1876 RYWPGQRIKADC-QLCICQDGR--------PRRCRLNPDCAVDCGWSSWSPWAKCLGPCG 1926
Y PG+ + C C CQD + P RC++ ++ C
Sbjct: 825 VYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNFPGNC-HFLA 883
Query: 1927 SQSIQWSFRSSNNPRPSGRGRQC 1949
+ WS P PSG+ C
Sbjct: 884 VHNEDWSISVELRPCPSGQTGTC 906
Score = 60.8 bits (146), Expect = 3e-08
Identities = 67/277 (24%), Positives = 103/277 (37%), Gaps = 74/277 (26%)
Query: 4682 CPHSCADLWDRVQCLQGPCRP--GCRCPPGQLVQ-DGRCVPISSCRCGLPSANASWELAP 4738
C SC L +R + P GC CP +G CV S C C + + P
Sbjct: 1131 CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDE----VMQP 1186
Query: 4739 AQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
+ + +D C C + L+C + P+ T++ C GG
Sbjct: 1187 GKLIHIDDNKCVCRDGILLC---QIPI---------------DLTLQ---NCSGGAEYVD 1225
Query: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACAT-SCPCLCWHLQPGAICVQEPCQPGCGCPG 4857
C ++R C+T + P +L PC+ GC CP
Sbjct: 1226 CSDPKAQRRTN---------------RTCSTRNIPVFDENL---------PCKRGCFCPE 1261
Query: 4858 GQLLHN-GTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
G + ++ G CV P CPC+ +G +E G+V + C C C G++SC
Sbjct: 1262 GMVRNSKGICVFPNDCPCS-----FG--------GREYDEGSVTSVGCNECTCIKGSWSC 1308
Query: 4917 SLVDCQV---PPGETWQQVAPGEL----GLCEQTCLE 4946
+ +CQ GE + G+ GLC+ + LE
Sbjct: 1309 TQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLE 1345
Score = 60.8 bits (146), Expect = 3e-08
Identities = 40/115 (34%), Positives = 54/115 (46%), Gaps = 15/115 (13%)
Query: 3300 VCQALPCPVTNCTAIEGAEYSPCGPP-----CPRSCDDLVHCVWR----CQPGCYCPPGQ 3350
+CQ +P +T GAEY C P R+C V+ C+ GC+CP G
Sbjct: 1205 LCQ-IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGM 1263
Query: 3351 VLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405
V +S G ICV P C C G+ + G+ GCN CTC++G +CT C
Sbjct: 1264 VRNSKG-ICVFPNDCPCS--FGGREYDEGS--VTSVGCNECTCIKGSWSCTQNEC 1313
Score = 60.5 bits (145), Expect = 4e-08
Identities = 53/217 (24%), Positives = 87/217 (40%), Gaps = 27/217 (12%)
Query: 4317 GPCSRSCGPGLASR------SGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSS 4370
G C SC GL + + SC L ++ D +C+ + +D GC CP+ ++
Sbjct: 1112 GLCEHSCPSGLVFKYNVKACNSSCRSL-SERDRSCDVEDVPVD--GC---TCPDAMYQNN 1165
Query: 4371 WSSWT-RCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEF 4429
+ + C + G C DG + + + +C+ E+
Sbjct: 1166 EGNCVLKSQCDCYINDEVMQPGKLIH--IDDNKCVCRDGILLCQIPIDLTLQNCSGGAEY 1223
Query: 4430 HACGSPCAG-----LCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGG-CIPPEECNCWHT 4483
C P A C+T ++LP C+ GC+CP+G++ + G C+ P +C C
Sbjct: 1224 VDCSDPKAQRRTNRTCSTRNIPVFDENLP-CKRGCFCPEGMVRNSKGICVFPNDCPC--- 1279
Query: 4484 SAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ 4520
+ G G +GC EC C +G CT CQ
Sbjct: 1280 --SFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQ 1314
Score = 60.5 bits (145), Expect = 4e-08
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 23/110 (20%)
Query: 3091 PRDKQWLDCAQGP--ASCAELSAPRGTNQTCHP--------------GCHCPSGMLLLNN 3134
P D +C+ G C++ A R TN+TC GC CP GM+ +
Sbjct: 1209 PIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSK 1268
Query: 3135 -VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGE 3183
+CV DCPC+ G Y GS C C+C+ G SW C + E
Sbjct: 1269 GICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKG------SWSCTQNE 1312
Score = 57.8 bits (138), Expect = 3e-07
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 2922 CAPGCTCPPGLFLHNAS-CLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSE 2980
C GC CP G+ ++ C+ + CPC G+ Y G++ + CN CTC+ G +CT
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSV-GCNECTCIKGSWSCTQN 1311
Query: 2981 RCPVAC 2986
C C
Sbjct: 1312 ECQTIC 1317
Score = 57.4 bits (137), Expect = 4e-07
Identities = 79/350 (22%), Positives = 114/350 (32%), Gaps = 113/350 (32%)
Query: 3479 GPWSPCDMCLGQSHRSRACSRPP-TPEGGRPCP----GNHTQSRPCQENSTQCTDCGGGQ 3533
GP + C + C + T E + C GN+ ++ C E T G
Sbjct: 1056 GPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKA--CAEKETYIVGWRTGL 1113
Query: 3534 SLHPCG---------QPCPRSCQDLSPGS-VCQPGSVGCQPTCGCPLGQL-SQDGLCVPP 3582
H C + C SC+ LS C V C CP + +G CV
Sbjct: 1114 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-CTCPDAMYQNNEGNCVLK 1172
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDC 3642
+ C C + + E ++PG+++ + C C GIL CQ D
Sbjct: 1173 SQCDC--------------------YINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDL 1212
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRL 3702
++CS GG E + C+ P R +RTCST+
Sbjct: 1213 T----------LQNCS---GGAEYVD---CSDPKAQ--RRTNRTCSTR------------ 1242
Query: 3703 YRECQPGEGCPFSCAHVTQQVGCFSEG--CEEGCHCPEGTFQHRLA-CV--QECPCVLTA 3757
+ F E C+ GC CPEG ++ CV +CPC
Sbjct: 1243 -------------------NIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFG- 1282
Query: 3758 WLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807
G E D G C C+C G SC+ ++C
Sbjct: 1283 -------------------GREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313
Score = 56.2 bits (134), Expect = 8e-07
Identities = 55/208 (26%), Positives = 69/208 (33%), Gaps = 37/208 (17%)
Query: 1713 WGQGRSRRCSPLGLLVLQN-------CPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEP 1765
W G P GL+ N C + ++C PVDG C +
Sbjct: 1109 WRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG--------CTCPDA 1160
Query: 1766 C----RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC 1821
G + QC N PG L K +DG +L Q C
Sbjct: 1161 MYQNNEGNCVLKSQCDCYINDE---VMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNC 1217
Query: 1822 APCP--LTCDDISGQV----TCPP--------DWPCGSPGCWCPEGQVLGSEGWCVWPRQ 1867
+ + C D Q TC + PC GC+CPEG V S+G CV+P
Sbjct: 1218 SGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPC-KRGCFCPEGMVRNSKGICVFPND 1276
Query: 1868 CPCLVDGARYWPGQRIKADCQLCICQDG 1895
CPC G Y G C C C G
Sbjct: 1277 CPCSFGGREYDEGSVTSVGCNECTCIKG 1304
Score = 55.5 bits (132), Expect = 1e-06
Identities = 34/104 (32%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 4062 CPAGMEVVTCAN-----RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGG-CVPIG 4115
C G E V C++ R R CS + V ++ C++GC CP+G + G CV
Sbjct: 1217 CSGGAEYVDCSDPKAQRRTNRTCST-RNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPN 1275
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTH 4159
C C+ G + GS CN C+C G SCT C H
Sbjct: 1276 DCPCSFG-GREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318
Score = 53.5 bits (127), Expect = 5e-06
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 10/99 (10%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD----GGCVPIGHC 4117
CP C P CS+ + D C GC CP+G L D G CV C
Sbjct: 762 CPEQHIYKECGPSNPATCSN----VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAEC 817
Query: 4118 DCTDAQGHSWAPGSQHQDAC-NNCSCQAGQLSCTAQPCP 4155
C ++ G + PG + C + C+CQ + SCT CP
Sbjct: 818 PC-ESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCP 855
Score = 53.1 bits (126), Expect = 7e-06
Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 13/110 (11%)
Query: 3300 VCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCV-WRCQPGCYCPPGQVLSSNG-- 3356
VC CP E Y CGP P +C ++ C GC CP G +L G
Sbjct: 756 VCGTQRCP-------EQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEK 808
Query: 3357 AICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
CV C C +G + PG P G + CTC + + +CT+ CP
Sbjct: 809 GKCVLKAECPCES--SGTVYQPGEVREGPCG-SQCTCQDAKWSCTEALCP 855
Score = 52.8 bits (125), Expect = 9e-06
Identities = 44/137 (32%), Positives = 59/137 (43%), Gaps = 23/137 (16%)
Query: 3669 SRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSE 3728
SR CA PG R+ S VC CP +Y+EC P P +C++V F +
Sbjct: 735 SRLCASDG-PGTFESWRSDSDVVCGTQRCPEQHIYKECGPSN--PATCSNVAP----FQD 787
Query: 3729 G-CEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLR 3787
C GC CPEG + ++ CVL A E T+ PG E+ G
Sbjct: 788 SECVSGCTCPEGYLLDDIG--EKGKCVLKAECPCESSGTVYQPG-------EVREG---- 834
Query: 3788 TSCGN-CSCAHGKLSCS 3803
CG+ C+C K SC+
Sbjct: 835 -PCGSQCTCQDAKWSCT 850
Score = 52.4 bits (124), Expect = 1e-05
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 14/98 (14%)
Query: 3090 CPRDKQWLDCA-QGPASCAELSAPRGTNQTCHPGCHCPSGMLLLN----NVCVPTQDCPC 3144
CP + +C PA+C+ ++ + + C GC CP G LL + CV +CPC
Sbjct: 762 CPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPC 819
Query: 3145 AHEGHLYPPGSTVVRPC-ENCSCVSGLIANCSSWPCAE 3181
G +Y PG PC C+C + W C E
Sbjct: 820 ESSGTVYQPGEVREGPCGSQCTCQD------AKWSCTE 851
Score = 51.6 bits (122), Expect = 2e-05
Identities = 51/209 (24%), Positives = 67/209 (32%), Gaps = 25/209 (11%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQE-GIVCQDDQVCQKGCRCPKGSLE-QDGGCVPIG 4115
CE CP+G+ C C L E C + V GC CP + +G CV
Sbjct: 1114 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 1173
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSC 4175
CDC PG N C C+ G L C P + S +
Sbjct: 1174 QCDCY-INDEVMQPGKLIHIDDNKCVCRDGILLCQI-----PIDLTLQNCSGGAEYVDCS 1227
Query: 4176 GPRGQQSRFRSSTS--------------GSWAPECREEQSQSQPCPQPSCPPLCLQGTRS 4221
P+ Q+ R+ ++ G + PE S+ CP C G R
Sbjct: 1228 DPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCP--CSFGGRE 1285
Query: 4222 RTLGDSWLQGECQRCSCTPEGVICEDTEC 4250
G G C C+C C EC
Sbjct: 1286 YDEGSVTSVG-CNECTCIKGSWSCTQNEC 1313
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/143 (28%), Positives = 50/143 (34%), Gaps = 27/143 (18%)
Query: 4785 ERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAI 4843
E R C GPG D++ C Q CPE + C S P C ++ P
Sbjct: 733 ELSRLCASDGPGTFESWRSDSDV--VCGTQRCPE---QHIYKECGPSNPATCSNVAPFQ- 786
Query: 4844 CVQEPCQPGCGCPGGQLL----HNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTV 4899
C GC CP G LL G CV CPC E PG V
Sbjct: 787 --DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPC-------------ESSGTVYQPGEV 831
Query: 4900 LTRNC-TRCVCHGGAFSCSLVDC 4921
C ++C C +SC+ C
Sbjct: 832 REGPCGSQCTCQDAKWSCTEALC 854
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/70 (38%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 2652 CVEGCRCPPGLLLHDT----RCLPLSECPCLVGEELKWPGVSFLLGNC-SQCVCEKGELL 2706
CV GC CP G LL D +C+ +ECPC + PG G C SQC C+ +
Sbjct: 790 CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG-EVREGPCGSQCTCQDAKWS 848
Query: 2707 CQPGGCPLPC 2716
C CP C
Sbjct: 849 CTEALCPGRC 858
Score = 47.8 bits (112), Expect = 3e-04
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFR-SAEQCHQEGGPCPRLCLTQGPG 2915
C+ L C + T C CP ++F+ + + C+ C L +
Sbjct: 1089 CTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS---CRSLS-ERDRS 1144
Query: 2916 IECTGFCAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGK 2974
+ GCTCP ++ +N +C+ +SQC C ++ ++ G + +D N C C G
Sbjct: 1145 CDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD-NKCVCRDGI 1203
Query: 2975 MAC 2977
+ C
Sbjct: 1204 LLC 1206
Score = 47.8 bits (112), Expect = 3e-04
Identities = 38/126 (30%), Positives = 49/126 (38%), Gaps = 37/126 (29%)
Query: 2606 LQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKA----NRSCSGH---------- 2651
LQ CSGG + YV C DPKA NR+CS
Sbjct: 1214 LQNCSGGAE------YVD---------------CSDPKAQRRTNRTCSTRNIPVFDENLP 1252
Query: 2652 CVEGCRCPPGLLLHDTR-CLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG 2710
C GC CP G++ + C+ ++CPC G G +G C++C C KG C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG-CNECTCIKGSWSCTQN 1311
Query: 2711 GCPLPC 2716
C C
Sbjct: 1312 ECQTIC 1317
Score = 47.0 bits (110), Expect = 5e-04
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 2627 CQKGLV-----PPCPPSCLD-PKANRSCSGHCV--EGCRCPPGLLLHDT-RCLPLSECPC 2677
C GLV C SC + +RSC V +GC CP + ++ C+ S+C C
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 1177
Query: 2678 LVGEELKWPGVSFLLGNCSQCVCEKGELLCQ 2708
+ +E+ PG + + ++CVC G LLCQ
Sbjct: 1178 YINDEVMQPGKLIHIDD-NKCVCRDGILLCQ 1207
Score = 45.1 bits (105), Expect = 0.002
Identities = 36/137 (26%), Positives = 51/137 (37%), Gaps = 23/137 (16%)
Query: 4639 WREAEALC---GGGCREPWAQES---CNGGPCPECEAQDTVFTLDCANQCPHSCADLWDR 4692
+ E LC G G E W +S C CPE +C P +C+++
Sbjct: 731 YSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYK-----ECGPSNPATCSNV--- 782
Query: 4693 VQCLQGPCRPGCRCPPGQLVQD----GRCVPISSCRCGLPSANASWELAPAQAVQLDC-Q 4747
C GC CP G L+ D G+CV + C C ++ P + + C
Sbjct: 783 APFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPC----ESSGTVYQPGEVREGPCGS 838
Query: 4748 NCTCVNESLVCPHQECP 4764
CTC + C CP
Sbjct: 839 QCTCQDAKWSCTEALCP 855
Score = 43.5 bits (101), Expect = 0.005
Identities = 34/111 (30%), Positives = 41/111 (36%), Gaps = 31/111 (27%)
Query: 3538 CGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD----GLCVPPAHCRCQYQPGA 3593
CG P +C +++P + C C CP G L D G CV A C C+
Sbjct: 771 CGPSNPATCSNVAPFQDSE-----CVSGCTCPEGYLLDDIGEKGKCVLKAECPCE----- 820
Query: 3594 MGIPENQSRSAGSRFSSWESLEPGEVVTGPC-DNCTCVAGILQCQEVPDCP 3643
SS +PGEV GPC CTC C E CP
Sbjct: 821 ---------------SSGTVYQPGEVREGPCGSQCTCQDAKWSCTEAL-CP 855
Score = 42.7 bits (99), Expect = 0.009
Identities = 28/109 (25%), Positives = 40/109 (36%), Gaps = 14/109 (12%)
Query: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLL----EQAGGCI 4473
C C + CG C+ Q + C GC CP+G L + G C+
Sbjct: 757 CGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE----CVSGCTCPEGYLLDDIGEKGKCV 812
Query: 4474 PPEECNCWHTSAAGAGMTLAPGDRLQLGC-KECECRRGELHCTSQGCQG 4521
EC C +G PG+ + C +C C+ + CT C G
Sbjct: 813 LKAECPC-----ESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPG 856
Score = 38.1 bits (87), Expect = 0.23
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 4/67 (5%)
Query: 4962 SGCVCQPGHFRS---QAGPCVPEDHCECWHLGRPHLPGSEWQEACES-CLCLSGRPVCTQ 5017
SGC C G+ + G CV + C C G + PG + C S C C + CT+
Sbjct: 792 SGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTE 851
Query: 5018 HCSPLTC 5024
P C
Sbjct: 852 ALCPGRC 858
Score = 35.0 bits (79), Expect = 1.9
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 9/76 (11%)
Query: 2638 SCLDPKANRSCSGHCVEGC--RCP---PGLLLHDTRCLPLSECPCLVGEELKWPGVSFLL 2692
+C D + S +EGC +CP P L + +C+ LSEC C + + GV +
Sbjct: 1604 TCKDQLVGQKFSS-LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGV--IE 1660
Query: 2693 GNCSQ-CVCEKGELLC 2707
NC + C C G+L C
Sbjct: 1661 DNCGRTCYCIAGQLEC 1676
Score = 34.3 bits (77), Expect = 3.3
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 13/91 (14%)
Query: 3319 YSPCGPPCPRSCDDLV--HCVWRCQPGCY--CP-PGQVLSSNGAICVQPGHCSCL--DLL 3371
Y PCG ++C D + GCY CP L N CV CSC D++
Sbjct: 1594 YEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI 1653
Query: 3372 TGQRHHPGARLARPDGCNHCTCLEGRLNCTD 3402
P + + C C+ G+L C++
Sbjct: 1654 ------PAGGVIEDNCGRTCYCIAGQLECSE 1678
Score = 34.3 bits (77), Expect = 3.3
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 23/104 (22%)
Query: 3537 PCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGL-CVPPAHCRCQYQPGAMG 3595
PCG ++C+D G GC C L ++ + CV + C C Y
Sbjct: 1596 PCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYN----- 1650
Query: 3596 IPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTCVAGILQCQE 3638
+ + G V+ C C C+AG L+C E
Sbjct: 1651 ----------------DVIPAGGVIEDNCGRTCYCIAGQLECSE 1678
Score = 33.9 bits (76), Expect = 4.3
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCY--CPKG---LLEQAGGCIPPEECNCW 4481
+ + CG+ A C L Q L GCY CP L E C+ EC+C+
Sbjct: 1592 WHYEPCGTVTAKTCKDQLVGQKFSSL---LEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648
Query: 4482 HTSAAGAGMTLAPGDRLQLGC-KECECRRGELHCT 4515
+ AG ++ C + C C G+L C+
Sbjct: 1649 YNDVIPAGGV------IEDNCGRTCYCIAGQLECS 1677
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 406 bits (1044), Expect = e-112
Identities = 392/1476 (26%), Positives = 547/1476 (37%), Gaps = 283/1476 (19%)
Query: 73 LCPIYKPPETRPAKWNRTVRTCC-----PGWGGAHCTEALAKASPEGHCFAMWQCQLQAG 127
LCP+ PP + + C PG G+ C E EG + C
Sbjct: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGESCL---- 1184
Query: 128 SANASAGSLEECCARPWGQSWWDGSSQACRS---CSSRHLPGSASSPA----LLQPLAGA 180
AS G + + P GQ+++ G C S C L SS QP G+
Sbjct: 1185 -PLASCGCVHQGTYHPPGQTFYPGPG--CDSLCHCQEGGLVSCESSSCGPHEACQPSGGS 1241
Query: 181 VGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP 240
+G + S+TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 1242 LGCV----AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH-------- 1289
Query: 241 QPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL--------------- 285
R + E V G VSV + + ++ L QW
Sbjct: 1290 ------RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLA 1343
Query: 286 ---------GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFME 336
G +V+ G+ V D + ++V + Q GLCG YNG P+DDF +
Sbjct: 1344 NGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQK 1403
Query: 337 PGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQG---CDPLGLIDADVEPGHLRAEAQDV 393
P G A A FGNSW +S CL G C P ++E + + ++
Sbjct: 1404 PNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY---QKEEF 1460
Query: 394 CHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACA 451
C L GP CH V P + C+F C G G +C+ +YV AC
Sbjct: 1461 CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQ 1513
Query: 452 RRHIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRG 510
H+ WR FC CP Y C C C A+ + C++ C GC+C G
Sbjct: 1514 AAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQ--CQDGCAEGCQCDSG 1571
Query: 511 LFWNGTLCVPAAHCPCYYCRQRYVPGDTVR--------------------------QLCN 544
+NG CVP C CY+ Y P TV Q+C
Sbjct: 1572 FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQ 1631
Query: 545 P------CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSF 582
P CV +D + Q +C A C + GD HY +FDGR + F
Sbjct: 1632 PSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDF 1691
Query: 583 WG-------GQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDSG- 634
G GC Q + ++ A S + ++V+ T+I +
Sbjct: 1692 QGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEI 1751
Query: 635 ---AVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHA 690
V VNG LP A+G +SV + +S LL+ G QV + + V +TL +
Sbjct: 1752 GKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYH 1810
Query: 691 HQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSAL 741
V GLCG +N +D + P G + SI + ++ G +G CP+
Sbjct: 1811 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----- 1865
Query: 742 LSPCTTHSQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLC 798
C C L S F CH V E F+ C+ VC D LC
Sbjct: 1866 ---CPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILC 1922
Query: 799 PVLSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGE----L 853
L++Y C G WR Q C + CP Y C P C C P
Sbjct: 1923 KALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCE 1982
Query: 854 GSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCT 913
G CV GC C G + + +CVP + N C C G +
Sbjct: 1983 GPCVEGCQCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY--- 2017
Query: 914 ARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDL 973
H F +A G C C C G VC P + L E C L
Sbjct: 2018 --HEAGSEF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GL 2058
Query: 974 CPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYP 1033
P SGQ H + CQA G PHYVT DG F +
Sbjct: 2059 LP---SGQ----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFDFQ 2093
Query: 1034 GACEYLLVREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAV 1085
G CEYLL G FTV+ N G+ ++ T+++ +++ + R +
Sbjct: 2094 GTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKL 2153
Query: 1086 TVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGL 1145
V+GV V P L +G ++++T GL+L +DG + V +++ + + GL
Sbjct: 2154 QVDGVFVALP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGL 2212
Query: 1146 CGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARC 1205
CG+++ D ++DL++ G +P + +P P PCT + C
Sbjct: 2213 CGNYNQDPADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDAC 2268
Query: 1206 GALLQ---PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHH 1262
G + PL CH VPP Q+++ CL DAC G LC A+ATY C G
Sbjct: 2269 GVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQ 2325
Query: 1263 V-RWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLH 1321
+ WR + C LQC YE CG +CP +C G C+ AC EGC C G +L
Sbjct: 2326 LGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG--CE-SACREGCVCDAGFVLS 2382
Query: 1322 GGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEA 1381
G C+ C C +P G V G CE G
Sbjct: 2383 GDTCVPVGQCGCLHDGRYYPLGEVFY-----------------PGPECERRCECGPGGHV 2425
Query: 1382 LCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417
CQE C PH ++C + C A GCG
Sbjct: 2426 TCQEGAACGPH-------EECRLEDGVQACHATGCG 2454
Score = 389 bits (999), Expect = e-107
Identities = 363/1317 (27%), Positives = 514/1317 (39%), Gaps = 217/1317 (16%)
Query: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVT-M 250
+A C + HY TFDGR Y +G C+Y + + + + +RV+ +
Sbjct: 469 TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
Query: 251 GPEEVLIQAGNVSV-KGQ----LVPEGQSWLLHGLSLQWL-----GDWLVLSGGLGVVVR 300
G V + +VS+ +G+ LV +S L LS L G V+ G+VV
Sbjct: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
Query: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
D +++S+ Q GLCG YNG P DDF+ P G LA A F +SW+L +
Sbjct: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
Query: 361 CLDAVEVAQGCDPLGLIDADVEPGHLR-AEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
C D + C PG + E +C L L+GPF CH + P + E
Sbjct: 649 CEDGCQ--NNCPA-------CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
Query: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYS 476
C++ C G + ++C ++Y QAC I + WR P C CP Y
Sbjct: 700 CVYDLCVVG-------GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYE 752
Query: 477 DCVSLCPPSCEAVGQGEEESCR-EECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVP 535
C CP SC G +C CV GC C G +G CVPA+ C C + + P
Sbjct: 753 LCGPACPTSCN--GAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAP 810
Query: 536 GDTV--------RQLCN----PCVCRDGRWHCAQALCPAE-------------CAVGGDG 570
G V R CN CRD + A C + C GD
Sbjct: 811 GQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDP 870
Query: 571 HYLTFDGRSYSFWGGQGCRYSLVQDYVKG------QLLILLEHGACDAGSCLHAISVSLE 624
HY++FDGR + F G C Y LV + ++L+ EH S A+ V
Sbjct: 871 HYVSFDGRRFDFMG--TCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEAR 928
Query: 625 DTHIQLRDS--GAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVA 681
+ +R G VLV+ LP+ A+G + V R ++ G V + + V
Sbjct: 929 GVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVT 988
Query: 682 YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ--------VAGKGR 733
+ +A + GLCG F + DD G + AF + +Q G
Sbjct: 989 -AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGD 1047
Query: 734 CPSEDSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCD 791
CP DS + + ++ C IL F+ECH +D + C+ C
Sbjct: 1048 CPKLDSLVAQQLQSKNE--------CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
Query: 792 PGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---P 847
S LC L+ YA C GA+ PWR++ LCP+ CP Y C+ C CG P
Sbjct: 1100 GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVP 1159
Query: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM--KECNR-CIC 904
CG C GC C G E C+P + C C + PG C+ C C
Sbjct: 1160 GGCG--SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
Query: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
QE GL +C + C C P+G + GCV +
Sbjct: 1217 QEGGLVSCESSSCGPHEACQ-----------------------PSGGSLGCVAVGSST-- 1251
Query: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
C+ SG PHY T
Sbjct: 1252 -----------CQASGD--------------------------------------PHYTT 1262
Query: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
Query: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 1323 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 1382
Query: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--------LSPLCPEPGD---L 1187
++ GLCG+++GD +D + G A +SW L P PG +
Sbjct: 1383 YQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCI 1442
Query: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
P H C + CG L P L CH V PQ + C++D C GG+
Sbjct: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 1500
Query: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHC 1303
LCS I Y C G HV WR++ C ++C YE C TC C P C
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP--QC 1558
Query: 1304 QVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQEGQWH 1361
Q C EGC C G L +G AC+ C C G P +VL +C CTC G+
Sbjct: 1559 Q-DGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK-- 1615
Query: 1362 CGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEEGC 1411
G C+E +C G+ +CQ +G CV HG C Q+ C + + C
Sbjct: 1616 ----GMVCQE--HSCKPGQ-VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
Score = 300 bits (767), Expect = 3e-80
Identities = 270/901 (29%), Positives = 362/901 (40%), Gaps = 138/901 (15%)
Query: 546 CVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL 605
C G+ C A A C GD HY TFDGR Y G C Y++V+ + L
Sbjct: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMG--TCSYTMVELCSEDDTLPAF 511
Query: 606 ------EHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLVNGQDVGLPWIGAEG-LSVR 656
EH S + ++V + L + G VLV+ Q LP +EG L V
Sbjct: 512 SVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVY 571
Query: 657 RASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVE 716
++ ++ G V + +A ++L R QV GLCG + + DDFLTP G +
Sbjct: 572 QSGPRAVVELVFGLVVTYDWDCQLA-LSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
Query: 717 TSIAAFASKFQV-AGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILH--SSVFQECHRL 773
FAS +++ G C CT +H + C +L F CH
Sbjct: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
Query: 774 VDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQE 832
+D PF +C+ +C LC LSAYA+ C + G S WR+ CP+ CP
Sbjct: 691 LDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSR 750
Query: 833 YRECAPACGQHC---GKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
Y C PAC C P +C CV GC C G + G CVP S C C +
Sbjct: 751 YELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFV-ASGGACVPASSCGCTFQGLQL 808
Query: 890 APGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPA 949
APG + +CQ R CT Q C SCPA
Sbjct: 809 APGQEVWAD---ELCQRR----CTCNGATHQVTC------------------RDKQSCPA 843
Query: 950 GSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
G ERC ++Q C
Sbjct: 844 G---------------ERC-------------------SVQNGLLGCY----------PD 859
Query: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLV-----REASGLFTVSAQNLPCGASGLTC 1064
R G CQ SG PHYV+FDG F + G C YLLV A F V +N G+ ++
Sbjct: 860 RFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSY 919
Query: 1065 TKALAVRLEGTVVHMLR---GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLT 1121
T+A+ V G V + R G+ + + + P + G + + R G ++ T GLT
Sbjct: 920 TRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ-VQVFRQGRDAVVRTDFGLT 978
Query: 1122 LLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--LSP 1179
+ +D RV ++ + + GLCG+F+GD ++DL R G A +SW+ P
Sbjct: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
Query: 1180 LC--PEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACG 1235
C EPGD P ++ + ++ CG L P F CH+++ PQ C+YD C
Sbjct: 1039 GCGATEPGDCPKLDSLVAQQL-QSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
Query: 1236 CDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE 1294
G LC A+ATYA C G V WRS+ELC L C YEAC CP +C +
Sbjct: 1098 LP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
Query: 1295 QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCT 1354
P PG C C EGC C EG L G +CL ASC C PPG
Sbjct: 1156 L-PVPG-GCG-SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFY------- 1205
Query: 1355 CQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C+ L C EG + E+ C PH + C GC A
Sbjct: 1206 ----------PGPGCDSLC-HCQEGGLVSCESSSCGPH-------EACQPSGGSLGCVAV 1247
Query: 1415 G 1415
G
Sbjct: 1248 G 1248
Score = 244 bits (624), Expect = 1e-63
Identities = 298/1223 (24%), Positives = 425/1223 (34%), Gaps = 247/1223 (20%)
Query: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
D +++G + P + + P P CP P T PA P G C
Sbjct: 1941 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 1993
Query: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 1994 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 2037
Query: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 2038 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 2094
Query: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 2095 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 2154
Query: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 2155 VDGVFVALPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 2206
Query: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV----------- 365
GLCG YN P DD GG A W++ G++ GC + V
Sbjct: 2207 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGECVSKPCPSPCTPE 2257
Query: 366 --EVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
E G D G+I A +GP CH V PA+Y + CL C
Sbjct: 2258 QQESFGGPDACGVISA------------------TDGPLAPCHGLVPPAQYFQGCLLDAC 2299
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYSDCVSLC 482
+G +C A+YV AC + WR+P FC CP Y C C
Sbjct: 2300 Q-------VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 2352
Query: 483 PPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPG 536
P SC ++ E C C GC C G +G CVP C C Y + + PG
Sbjct: 2353 PVSCPSL--SAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 2410
Query: 537 DTVRQLC-------------------NPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDG 577
+ C C DG C C C G HY+T DG
Sbjct: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDG 2469
Query: 578 RSYSFWGGQGCRYSLVQ----DYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDS 633
R Y G C Y L Q I+LE A AG L + V++ + L
Sbjct: 2470 RVYDLHG--SCSYVLAQVCHPKPGDEDFSIVLEKNA--AGD-LQRLLVTVAGQVVSLAQG 2524
Query: 634 GAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQV 693
V V+G+ V LP + + V +L G ++L+ D +++ ++
Sbjct: 2525 QQVTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFD-GDAHLLMSIPSPFRGRL 2582
Query: 694 QGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL--LSPCTTHSQR 751
GLCG F N DDF+ P G +S+ F + ++ G + E C
Sbjct: 2583 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETA 2642
Query: 752 HAFAEAACAILHS--SVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCA 809
+ AC L + F C ++ ++ +C+ +C LC L+AY C
Sbjct: 2643 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 2702
Query: 810 QEG-ASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPED-CGELGSCVAGCNCPLGLL 867
G A PWR + CP+ CP Y C C C G C GC C L
Sbjct: 2703 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFL 2762
Query: 868 WDPEGQCVPPSLCPCQLGARRYAPGSATM--KECN-RCICQERGLWNCTARHCPSQAFC- 923
+G C+P C C RY P ++++ +C+ RC C C A CP C
Sbjct: 2763 LS-QGVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE 2820
Query: 924 ----PRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHS 979
R G C+L S AN + G+ G PG L RC P L +++
Sbjct: 2821 VKAEARNCWATRGLCVL---SVGANLTTFDGAR-GATTSPGVYELSSRC--PGL---QNT 2871
Query: 980 GQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYL 1039
WY A +Q +C G+ +A G H DG+ P
Sbjct: 2872 IPWYRVVAEVQ------ICH------------GKTEAVGQVHIFFQDGMVTLTP------ 2907
Query: 1040 LVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYT 1099
+ V VNG+ V P
Sbjct: 2908 ------------------------------------------NKGVWVNGLRVDLPAEKL 2925
Query: 1100 GPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRS 1159
R LL+ G+ + +V V +S G++ G CG+FDGD +ND
Sbjct: 2926 ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHD 2985
Query: 1160 RQGVLEPTAELAAHSWRLSPLCP 1182
Q + A WR P
Sbjct: 2986 SQ------EKPAMEKWRAQDFSP 3002
Score = 196 bits (497), Expect = 7e-49
Identities = 164/561 (29%), Positives = 228/561 (40%), Gaps = 55/561 (9%)
Query: 836 CAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARR--YAPGS 893
C P + G P+ CG + S G P L P L CQ+ P
Sbjct: 2254 CTPEQQESFGGPDACGVI-SATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAV 2312
Query: 894 ATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY--APGACLLTCDSPSANHSCPAGS 951
AT + + G W CP Q CP Y +C ++C S SA C +
Sbjct: 2313 ATYVAACQAAGAQLGEWR-RPDFCPLQ--CPAHSHYELCGDSCPVSCPSLSAPEGCESAC 2369
Query: 952 TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWY------LPNATIQEDCN-------VC-- 996
+GCVC G VL + CVP C C H G++Y P + C C
Sbjct: 2370 REGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 2429
Query: 997 --------VCR----GRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREA 1044
CR + H TG GRC A+G HY+T DG + G+C Y+L +
Sbjct: 2430 GAACGPHEECRLEDGVQACHATG---CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVC 2486
Query: 1045 SGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLS 1104
++ + + L V + G VV + +G+ VTV+G +V P V G +
Sbjct: 2487 HPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALP-VAVG-RVR 2544
Query: 1105 LRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
+ G ++L T GL LL+DG +L+ + FRGR+ GLCG+F+G+ S+D G
Sbjct: 2545 VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA 2604
Query: 1165 EPTAELAAHSWRL---SPLCPEP-GDLPHPCTMNTHRAGW-ARARCGALLQPL--FTLCH 1217
+ E +WR S C E G P + A + + CG L P F C
Sbjct: 2605 ASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQ 2664
Query: 1218 AEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCE 1276
A + P +++ C+YD C GD LC ++A Y C G V+ WR+ C L C
Sbjct: 2665 AVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCP 2722
Query: 1277 GGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWG 1336
Y C TC +C G C EGC C + LL G C+ C C
Sbjct: 2723 AHSHYSICTRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTHN 2779
Query: 1337 RNSFP-PGSVLQKDCG-NCTC 1355
P S+L DC C+C
Sbjct: 2780 GRYLPVNSSLLTSDCSERCSC 2800
Score = 83.2 bits (204), Expect = 6e-15
Identities = 79/281 (28%), Positives = 98/281 (34%), Gaps = 43/281 (15%)
Query: 4526 SEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPAT 4585
+ W E P PCLPP+ P S + H P L + + C
Sbjct: 1417 NSWEEVVPDSPCLPPTPCPPGSEDCIPSH----------KCPPELEKKYQKEEFC----- 1461
Query: 4586 GRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
G T PLS DP C + L + CS + +
Sbjct: 1462 -----GLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQ 1513
Query: 4646 CGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
GG EPW E+ CP + CA+ C C+ L QC G C GC+
Sbjct: 1514 AAGGHVEPWRTETFCPMECPPNSHYEL-----CADTCSLGCSALSAPPQCQDG-CAEGCQ 1567
Query: 4706 CPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQE 4762
C G L CVPI C C + P Q V +D C Q CTC + +VC
Sbjct: 1568 CDSGFLYNGQACVPIQQCGC----YHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHS 1623
Query: 4763 C---PVLGPWSAWSSC--SAPCGGGTMERHRTC--EGGPGV 4796
C V P SC PC G T TC +GG GV
Sbjct: 1624 CKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGV 1664
Score = 79.3 bits (194), Expect = 9e-14
Identities = 99/366 (27%), Positives = 131/366 (35%), Gaps = 100/366 (27%)
Query: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
W+ V PC P CPPG +D C+P C CGL S+ ++
Sbjct: 1419 WEEV-VPDSPCLPPTPCPPGS--ED--CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
Query: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
+L Q DC C+ N S++C + V S+C A GG +E RT
Sbjct: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGHVEPWRT 1524
Query: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
+T CP ECPP CA +C C L C Q+
Sbjct: 1525 -------------ETF---------CPMECPPNSHYELCADTCSLGCSALSAPPQC-QDG 1561
Query: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
C GC C G L + CVP C C + + + P TVL NC +C
Sbjct: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE------------PEQTVLIDNCRQQC 1609
Query: 4908 VCHGG-AFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
CH G C C+ PG+ Q G + C T+ C G C
Sbjct: 1610 TCHAGKGMVCQEHSCK--PGQVCQ--PSGGILSC----------VTKDPC-----HGVTC 1650
Query: 4967 QPGHF---RSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQ 5017
+P + G C+P CW G PH ++Q C L +G P V TQ
Sbjct: 1651 RPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQ 1710
Query: 5018 HCSPLT 5023
+P T
Sbjct: 1711 GLTPFT 1716
Score = 75.1 bits (183), Expect = 2e-12
Identities = 129/543 (23%), Positives = 175/543 (32%), Gaps = 127/543 (23%)
Query: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
+P C CPA C CP C+ C + C +GC C G + G CVP
Sbjct: 737 SPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFVASGGACVP 795
Query: 4114 IGHCDCTDAQGHSWAPGSQ-----------------HQDACNN---------CSCQAGQL 4147
C CT QG APG + HQ C + CS Q G L
Sbjct: 796 ASSCGCT-FQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854
Query: 4148 SC------TAQPCPPPTHCAWS--HWSAWSPCSH----SCGPRGQQSRFR--------SS 4187
C T Q P + ++ + C++ SCG FR S
Sbjct: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS 914
Query: 4188 TSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICED 4247
+ S+ R E + + P L + L G+ Q + V+ D
Sbjct: 915 QTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 974
Query: 4248 TECAVPEAWT------LWSSWSDCPVS-CGG--GNQVRTRACRAAAPHHRSPPCLGPDTQ 4298
V W + SS+++ CG G+ A R ++ L
Sbjct: 975 FGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG---QAANALAFGNS 1031
Query: 4299 TRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCP---CLMAKADPTCNSTFLHLDTQ 4355
+++ PG CG A+ G CP L+A+ + N + D +
Sbjct: 1032 WQEETRPG----------------CG---ATEPGDCPKLDSLVAQQLQSKNECGILADPK 1072
Query: 4356 G----CYSGPCPE----ECVWSSWSSWTRCSCRVLVQQRYRHQGPASRG-ARAGAPCTRL 4406
G C+S P+ +CV+ RC +L Q GP A A C
Sbjct: 1073 GPFRECHSKLDPQGAVRDCVYD------RC---LLPGQ----SGPLCDALATYAAACQAA 1119
Query: 4407 DGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLP-------PCQPGC 4459
P SC P + AC C LS C DLP C GC
Sbjct: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYGCP------LS---CGDLPVPGGCGSECHEGC 1170
Query: 4460 YCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAPGDRLQLGCKE-CECRRGEL-HCTS 4516
C +G C+P C C H G T PG GC C C+ G L C S
Sbjct: 1171 VCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES 1226
Query: 4517 QGC 4519
C
Sbjct: 1227 SSC 1229
Score = 74.7 bits (182), Expect = 2e-12
Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C+ G P SC +L P G CH GC C G L C+P C C
Sbjct: 1133 PLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCV 1192
Query: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
H+G +PPG T C++ C C G + +C S C P C S G
Sbjct: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG----------PHEACQPSGGSL 1242
Query: 3203 RC 3204
C
Sbjct: 1243 GC 1244
Score = 69.7 bits (169), Expect = 7e-11
Identities = 41/123 (33%), Positives = 48/123 (39%), Gaps = 13/123 (10%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 2336 PLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 2395
Query: 3146 HEGHLYPPGSTVV--RPCE-NCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
H+G YP G CE C C G C EG + P +C G
Sbjct: 2396 HDGRYYPLGEVFYPGPECERRCECGPG-----GHVTCQEG----AACGPHEECRLEDGVQ 2446
Query: 3203 RCH 3205
CH
Sbjct: 2447 ACH 2449
Score = 68.6 bits (166), Expect = 2e-10
Identities = 66/243 (27%), Positives = 86/243 (35%), Gaps = 41/243 (16%)
Query: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
G AGN SW P PC C G + + +++ P P + YQ+
Sbjct: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCP-------PELEKKYQKE 1458
Query: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
FC L + P P S C + C GG +L S CS+ +
Sbjct: 1459 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 1510
Query: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
AG H C CP CA+ C CS L CQD C +GC+
Sbjct: 1511 ACQAAGG-HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQ 1567
Query: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
C G L CVPI C C + + D C C+C AG+ + C C P
Sbjct: 1568 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPG 1627
Query: 4158 THC 4160
C
Sbjct: 1628 QVC 1630
Score = 67.0 bits (162), Expect = 5e-10
Identities = 35/99 (35%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C + SCA LS G C GC C LL VC+P QDC C
Sbjct: 2718 PLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCT 2777
Query: 3146 HEGHLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEG 3182
H G P S+++ E CSC S C + C G
Sbjct: 2778 HNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
Score = 65.1 bits (157), Expect = 2e-09
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Query: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + + CA + C+ LSAP C GC C SG L CVP Q C C
Sbjct: 1529 PMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCY 1588
Query: 3146 HEGHLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
H G Y P TV + C + C+C +G C C G+
Sbjct: 1589 HNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQ 1628
Score = 63.5 bits (153), Expect = 5e-09
Identities = 64/211 (30%), Positives = 76/211 (36%), Gaps = 54/211 (25%)
Query: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP----PPKNG-GAPCPGASQERAP--- 2603
G+W W+ W C SC + R P P +G G P P
Sbjct: 1844 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESF 1903
Query: 2604 ---CGLQPCSGGTD----CELGRVYVSADLCQKGLV------------------------ 2632
C L C GG D C+ YV+A CQ V
Sbjct: 1904 FKGCVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEVC 1961
Query: 2633 -PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWPG 2687
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C G
Sbjct: 1962 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 2021
Query: 2688 VSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
F G CSQ C C G L+C P C L
Sbjct: 2022 SEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2052
Score = 62.4 bits (150), Expect = 1e-08
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 1848 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLASGTGGPFTTCHAHVPP 1900
Query: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
C GG R C +LA C D Q C CPEN +
Sbjct: 1901 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 1958
Query: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 1959 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 2013
Query: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 2014 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 2060
Score = 61.2 bits (147), Expect = 3e-08
Identities = 45/123 (36%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
C CP SC C PC GC C PG + G CVP SSC C +LA
Sbjct: 754 CGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGL----QLA 809
Query: 4738 PAQAVQLD--CQ-NCTC--VNESLVC-PHQECPVLGPWSAWSSCSAPCG--GGTMERHRT 4789
P Q V D CQ CTC + C Q CP A CS G G +R T
Sbjct: 810 PGQEVWADELCQRRCTCNGATHQVTCRDKQSCP------AGERCSVQNGLLGCYPDRFGT 863
Query: 4790 CEG 4792
C+G
Sbjct: 864 CQG 866
Score = 59.3 bits (142), Expect = 1e-07
Identities = 44/141 (31%), Positives = 51/141 (36%), Gaps = 30/141 (21%)
Query: 2590 GGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCS 2649
G P S+E P P S C G CP SC D C
Sbjct: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYG----------------CPLSCGDLPVPGGCG 1163
Query: 2650 GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG-NC-SQCVCEKGELL- 2706
C EGC C G L CLPL+ C C+ PG +F G C S C C++G L+
Sbjct: 1164 SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVS 1223
Query: 2707 -----------CQPGGCPLPC 2716
CQP G L C
Sbjct: 1224 CESSSCGPHEACQPSGGSLGC 1244
Score = 59.3 bits (142), Expect = 1e-07
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
CS++ + C T+ C +CP N + E C C C
Sbjct: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHY---ELC---ADTCSLGCSALSAP 1555
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC-NNCTCVSGK 2974
+C CA GC C G + +C+P QC C +G Y +D+C CTC +GK
Sbjct: 1556 PQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 1615
Query: 2975 -MACTSERC 2982
M C C
Sbjct: 1616 GMVCQEHSC 1624
Score = 58.2 bits (139), Expect = 2e-07
Identities = 73/259 (28%), Positives = 89/259 (34%), Gaps = 63/259 (24%)
Query: 3600 QSRSAGSRFSSW-ESLEPGEVVTGPCDNCTCVAGIL--QCQEVPDC---PDPGVWSSWGP 3653
Q+ +A + +SW E PG T P D C + ++ Q Q +C DP GP
Sbjct: 1021 QAANALAFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPK-----GP 1074
Query: 3654 WEDCSVSCGGGEQLRS---RRCARPPCPGPARQSRTCSTQVCREAG-------------- 3696
+ +C +R RC P GP + C+ AG
Sbjct: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
Query: 3697 -CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQECPC 3753
CP Y C GCP SC + GC SE C EGC C EG +C + C C
Sbjct: 1135 SCPPHSHYEACS--YGCPLSCGDLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGC 1191
Query: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKL-SCSLDDCFEADG 3812
V T PGQ PG DS C C G L SC C
Sbjct: 1192 VHQ--------GTYHPPGQTFYPGPGCDS---------LCHCQEGGLVSCESSSC----- 1229
Query: 3813 GFGPWSPWGPCSRSCGGLG 3831
P C S G LG
Sbjct: 1230 -----GPHEACQPSGGSLG 1243
Score = 57.0 bits (136), Expect = 5e-07
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 2604 CGLQPCSGGTD----CELGRVYVSADLCQKGLVPP----------CPPS----------- 2638
C C GG + C YVSA G V P CPP+
Sbjct: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
Query: 2639 --CLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNC- 2695
C A C C EGC+C G L + C+P+ +C C P + L+ NC
Sbjct: 1547 LGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
Query: 2696 SQCVCEKGE-LLCQPGGC 2712
QC C G+ ++CQ C
Sbjct: 1607 QQCTCHAGKGMVCQEHSC 1624
Score = 56.2 bits (134), Expect = 8e-07
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CP C+ CP C DL C + C +GC C +G C+P+ C
Sbjct: 1132 CPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSE--CHEGCVCDEGFALSGESCLPLASC 1189
Query: 4118 DCTDAQGHSWAPGSQHQ--DACNN-CSCQAGQL-SCTAQPCPPPTHC 4160
C QG PG C++ C CQ G L SC + C P C
Sbjct: 1190 GCVH-QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEAC 1235
Score = 56.2 bits (134), Expect = 8e-07
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
C GH P C P + C C+ C+ + CQD C GC C
Sbjct: 1512 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD--GCAEGCQCD 1569
Query: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL-GCK-ECECRRGE-LHCTSQGC 4519
G L C+P ++C C+H G+ P + + C+ +C C G+ + C C
Sbjct: 1570 SGFLYNGQACVPIQQCGCYHN-----GVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC 1624
Query: 4520 Q 4520
+
Sbjct: 1625 K 1625
Score = 55.1 bits (131), Expect = 2e-06
Identities = 69/260 (26%), Positives = 91/260 (35%), Gaps = 39/260 (15%)
Query: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 1812 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 1868
Query: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLR 4027
RL Y PG G L + F A P + + C GGG R
Sbjct: 1869 DRLEQYEGPGFCGP-----LASGTGGPFTTCHAHVPPESFFKGCVLDVC---MGGGD--R 1918
Query: 4028 SRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC---SD 4081
C + S AG E +A+ + CE CP C CP C +
Sbjct: 1919 DILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSPAP 1974
Query: 4082 LQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQHQ 4134
L VC+ C +GC+C G + CVP+ + C C +A WA G+ Q
Sbjct: 1975 LTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 2032
Query: 4135 DACNNCSCQAGQLSCTAQPC 4154
C G L CT C
Sbjct: 2033 WC--RCGPGGGSLVCTPASC 2050
Score = 55.1 bits (131), Expect = 2e-06
Identities = 56/211 (26%), Positives = 68/211 (32%), Gaps = 57/211 (27%)
Query: 3248 GCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQP---------------------PPQG 3286
G RA GW P W C SC R + P PP+
Sbjct: 1844 GSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPES 1902
Query: 3287 LG-----DYCEGPRAQGEVCQALPCPVTNCTAI------------------EGAEYSPCG 3323
D C G + +C+AL V C A E + Y CG
Sbjct: 1903 FFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG 1962
Query: 3324 PPCPRSCDDLVH------CVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHH 3377
PPCP SC C C GC C G VLS++ + + G C C G H
Sbjct: 1963 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNG-CGC--WANGTYHE 2019
Query: 3378 PGARLARPDGCNH-CTCLE--GRLNCTDLPC 3405
G+ C+ C C G L CT C
Sbjct: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASC 2050
Score = 54.7 bits (130), Expect = 2e-06
Identities = 39/125 (31%), Positives = 46/125 (36%), Gaps = 11/125 (8%)
Query: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
CP CP C +CP C + C PC GC C G + G CVP ++C
Sbjct: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 800
Query: 4874 CTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVA 4933
CT L L E A EL RC C+G + D Q P V
Sbjct: 801 CTFQGLQ--LAPGQEVWADELCQ--------RRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
Query: 4934 PGELG 4938
G LG
Sbjct: 851 NGLLG 855
Score = 54.7 bits (130), Expect = 2e-06
Identities = 68/233 (29%), Positives = 81/233 (34%), Gaps = 57/233 (24%)
Query: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
C S PC SP TP Q S GP C + +T PL P
Sbjct: 2245 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 2283
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
P + CLL C G G P + + AC Q LG++
Sbjct: 2284 LVPPAQYFQGCLLDACQVQGHPGGLCP----------AVATYVAACQAAGAQ-LGEW--- 2329
Query: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQ 3350
+ + C L CP + Y CG CP SC L C C+ GC C G
Sbjct: 2330 --RRPDFCP-LQCPAHS-------HYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGF 2379
Query: 3351 VLSSNGAICVQPGHCSCLD----LLTGQRHHPGARLARPDGC---NHCTCLEG 3396
VLS G CV G C CL G+ +PG R C H TC EG
Sbjct: 2380 VLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 2430
Score = 54.3 bits (129), Expect = 3e-06
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 9/126 (7%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C C C+ L C C +GC C L G C+P+ C
Sbjct: 2717 CPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDC 2774
Query: 4118 DCTDAQGHSWAPGSQHQDACN-NCSCQAGQ-LSCTAQPCPPPTHC-----AWSHWSAWSP 4170
CT + S C+ CSC + L+C A CPP C A + W+
Sbjct: 2775 GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL 2834
Query: 4171 CSHSCG 4176
C S G
Sbjct: 2835 CVLSVG 2840
Score = 53.9 bits (128), Expect = 4e-06
Identities = 61/243 (25%), Positives = 80/243 (32%), Gaps = 33/243 (13%)
Query: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 2226 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 2285
Query: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
P Q +G C ++A C +Q + C QCP + +
Sbjct: 2286 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHY 2345
Query: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
E C G CP C + C C GC C G L +C+P QC C G+
Sbjct: 2346 ---ELC---GDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 2399
Query: 2953 LYASGAM-------ARLDSC---NNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCN 3002
Y G + R C + TC G E C + G C N
Sbjct: 2400 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 2459
Query: 3003 VGI 3005
GI
Sbjct: 2460 GGI 2462
Score = 53.5 bits (127), Expect = 5e-06
Identities = 57/200 (28%), Positives = 70/200 (35%), Gaps = 28/200 (14%)
Query: 3477 PWGPWSPC--DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQS 3534
P GP C D+CLG + S CS G H + P + + +C
Sbjct: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVE--PWRTETFCPMECPPNSH 1537
Query: 3535 LHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QY 3589
C C C LS CQ G C C C G L CVP C C Y
Sbjct: 1538 YELCADTCSLGCSALSAPPQCQDG---CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYY 1594
Query: 3590 QPGAMGIPENQSRS----AGSRFSSWE-SLEPGEVVTGPCDNCTCVAGILQCQEVPDCPD 3644
+P + +N + AG E S +PG+V C GIL C V P
Sbjct: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQV-------CQPSGGILSC--VTKDPC 1645
Query: 3645 PGVWSSWGPWEDCSVSCGGG 3664
GV + P E C G G
Sbjct: 1646 HGV--TCRPQETCKEQGGQG 1663
Score = 53.5 bits (127), Expect = 5e-06
Identities = 59/224 (26%), Positives = 77/224 (34%), Gaps = 40/224 (17%)
Query: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 2232 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2288
Query: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
G + +G PG VA CQA + + CP +CP C
Sbjct: 2289 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC 2348
Query: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 2349 GDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPL---- 2403
Query: 4888 EEQAQELPPGTVLTRNCT-----RCVCHGGAFSCSLVDCQVPPG 4926
+ PG R C C GA +C++ G
Sbjct: 2404 ---GEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
Score = 52.8 bits (125), Expect = 9e-06
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 18/118 (15%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLHNASCL 2940
C CP N + E C G CP C C+G C GC C PG +C+
Sbjct: 741 CPLSCPANSRY---ELC---GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACV 794
Query: 2941 PRSQCPCQLHG-------QLYASGAMARLDSCNNC----TCVSGKMACTSERCPVACG 2987
P S C C G +++A R +CN TC + ERC V G
Sbjct: 795 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNG 852
Score = 52.8 bits (125), Expect = 9e-06
Identities = 58/233 (24%), Positives = 75/233 (32%), Gaps = 55/233 (23%)
Query: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 2252 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 2301
Query: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
G P CP T CQ Q + C CG CP SC LS
Sbjct: 2302 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 2361
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
C+ C+ C C G + CVP C C + G +
Sbjct: 2362 PEGCESA---CREGCVCDAGFVLSGDTCVPVGQCGCLHD--------------GRYYPLG 2404
Query: 3612 ESLEPGEVVTGPCD-NCTC-VAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCG 3662
E PG C+ C C G + CQE C GP E+C + G
Sbjct: 2405 EVFYPGP----ECERRCECGPGGHVTCQEGAAC---------GPHEECRLEDG 2444
Score = 52.8 bits (125), Expect = 9e-06
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
C SC C+ C EGC C LL C+P+ +C C S L +
Sbjct: 2734 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 2793
Query: 2695 CSQ-CVCEKGE-LLCQPGGCP 2713
CS+ C C L CQ GCP
Sbjct: 2794 CSERCSCSSSSGLTCQAAGCP 2814
Score = 52.4 bits (124), Expect = 1e-05
Identities = 64/241 (26%), Positives = 85/241 (35%), Gaps = 35/241 (14%)
Query: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC-PVLGPWSA-----WSSCSAP 4778
CG +L A QL +N + P +EC L P A + C P
Sbjct: 1040 CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
Query: 4779 CGGGTMERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCW 4836
G + C+ A CQA + + CP CPP AC+ CP C
Sbjct: 1100 GQSGPL-----CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1154
Query: 4837 HLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPP 4896
L C E C GC C G L +C+P +C C T Q P
Sbjct: 1155 DLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGCVHQG-------TYHPPGQTFYP 1206
Query: 4897 GTVLTRNC-TRCVC-HGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQS 4954
G C + C C GG SC C P E Q + G LG C+ + ++ Q+
Sbjct: 1207 GP----GCDSLCHCQEGGLVSCESSSC--GPHEACQP-SGGSLG-----CVAVGSSTCQA 1254
Query: 4955 N 4955
+
Sbjct: 1255 S 1255
Score = 52.0 bits (123), Expect = 2e-05
Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 27/140 (19%)
Query: 3289 DYCEGPRAQGEVCQALPCPVTNCTAIEG------------------AEYSPCGPPCPRSC 3330
D C P G +C AL C A + Y C CP SC
Sbjct: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSC 1153
Query: 3331 DDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDG 3387
DL C C GC C G LS G C+ C C+ G H PG G
Sbjct: 1154 GDLPVPGGCGSECHEGCVCDEGFALS--GESCLPLASCGCVH--QGTYHPPGQTFYPGPG 1209
Query: 3388 CNH-CTCLEGRL-NCTDLPC 3405
C+ C C EG L +C C
Sbjct: 1210 CDSLCHCQEGGLVSCESSSC 1229
Score = 51.6 bits (122), Expect = 2e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 2335 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 2392
Query: 4118 DCTD-----AQGHSWAPGSQHQDACNNCSC-QAGQLSC-TAQPCPPPTHC 4160
C G + PG + + C C G ++C C P C
Sbjct: 2393 GCLHDGRYYPLGEVFYPGPECE---RRCECGPGGHVTCQEGAACGPHEEC 2439
Score = 50.8 bits (120), Expect = 3e-05
Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 17/116 (14%)
Query: 3291 CEGPRAQGEVCQALPCPV------TNC--TAIEGAEYSPCGPPCPRSCDDLV---HCVWR 3339
C G A + C L V NC + + Y CGP CP SC+ +C R
Sbjct: 715 CRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR 774
Query: 3340 -CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGC-NHCTC 3393
C GC C PG V S G CV C C G + PG + + C CTC
Sbjct: 775 PCVEGCVCLPGFVAS--GGACVPASSCGC--TFQGLQLAPGQEVWADELCQRRCTC 826
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 1965 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 2023
Query: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
W + S C G + C+P +C GE L P C P E P
Sbjct: 2024 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2083
Query: 5055 LLTELRNFTKGTC 5067
L R +GTC
Sbjct: 2084 TLDGHRFDFQGTC 2096
Score = 49.7 bits (117), Expect = 8e-05
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 2633 PPCPPSCLDPKANRSCSGH-CVEGCRCPPGLLLHDTRCLPLSECPC 2677
P CP SC A +CSG CVEGC C PG + C+P S C C
Sbjct: 756 PACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CP SC A C C EGC C G +L C+P+ +C CL G F G
Sbjct: 2352 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 2411
Query: 2695 CSQCVCEKGELLCQPGG 2711
+ CE C PGG
Sbjct: 2412 ECERRCE-----CGPGG 2423
Score = 47.4 bits (111), Expect = 4e-04
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 19/144 (13%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPC 3144
P CP + ++ C P SC +AP + + C GC C G + CVP C C
Sbjct: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Query: 3145 AHEGHLYPPGSTV------VRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSAS 3198
+G PG V R C C+ + + C GE +CS
Sbjct: 802 TFQGLQLAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAGE----------RCSVQ 850
Query: 3199 CGPARCHRHRFCARSPSAVPSTVA 3222
G C+ RF S P V+
Sbjct: 851 NGLLGCYPDRFGTCQGSGDPHYVS 874
Score = 47.4 bits (111), Expect = 4e-04
Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 9/130 (6%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
C SLA C + T C CP + + + Q G C L G
Sbjct: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ--GSCAALSGLTG-- 2746
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ-LYASGAMARLDSCNNCTCVSGK 2974
CT C GC C L C+P C C +G+ L + ++ D C+C S
Sbjct: 2747 --CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 2804
Query: 2975 -MACTSERCP 2983
+ C + CP
Sbjct: 2805 GLTCQAAGCP 2814
Score = 47.0 bits (110), Expect = 5e-04
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 37/230 (16%)
Query: 4836 WHLQPGAICVQEPCQPGC-GCPGGQLLH---NGTCV-------PPTACPCTQHSLPWGLT 4884
W L G ++ CQ C C GQ H + C P C T P+
Sbjct: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPF--- 696
Query: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHG-GAFSCSLVDCQVPPGETWQQVAPGELG----- 4938
LE+ +L + +C G A++ + ++ + G+ W+ A L
Sbjct: 697 --LEQCVYDL----CVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLSCPANS 749
Query: 4939 ---LCEQTC-LEMNATKTQSNCSSARA-SGCVCQPGHFRSQAGPCVPEDHCECWHLGRPH 4993
LC C N SNCS GCVC PG F + G CVP C C G
Sbjct: 750 RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQL 808
Query: 4994 LPGSE-W-QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG--SCCP 5039
PG E W E C+ +G +C GE ++ G C P
Sbjct: 809 APGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
Score = 47.0 bits (110), Expect = 5e-04
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 13/126 (10%)
Query: 4642 AEALCGGGCREPWAQESCNGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPC 4700
A G +PW +S CP C A C C SCA L C C
Sbjct: 2699 AACQAAGVAVKPWRTDSF----CPLHCPAHSHYSI--CTRTCQGSCAALSGLTGCTTR-C 2751
Query: 4701 RPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDC-QNCTCVNES-LVC 4758
GC C L+ G C+P+ C C + N + + + DC + C+C + S L C
Sbjct: 2752 FEGCECDDRFLLSQGVCIPVQDCGC---THNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 2808
Query: 4759 PHQECP 4764
CP
Sbjct: 2809 QAAGCP 2814
Score = 46.6 bits (109), Expect = 6e-04
Identities = 49/194 (25%), Positives = 65/194 (33%), Gaps = 31/194 (15%)
Query: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
A CQA + CP CP S C +C C L C C GC C
Sbjct: 2699 AACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCEC 2757
Query: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELP-PGTVLTRNCT-RCVCHGGA 4913
LL G C+P C CT + + LP ++LT +C+ RC C +
Sbjct: 2758 DDRFLLSQGVCIPVQDCGCTHN-------------GRYLPVNSSLLTSDCSERCSCSSSS 2804
Query: 4914 -FSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFR 4972
+C C PPG +CE N T+ C + + G
Sbjct: 2805 GLTCQAAGC--PPGR-----------VCEVKAEARNCWATRGLCVLSVGANLTTFDGARG 2851
Query: 4973 SQAGPCVPEDHCEC 4986
+ P V E C
Sbjct: 2852 ATTSPGVYELSSRC 2865
Score = 45.8 bits (107), Expect = 0.001
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 25/181 (13%)
Query: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 1900 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 1955
Query: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
C CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 1956 SHYEVCGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 2014
Query: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 2015 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 2064
Query: 4938 G 4938
G
Sbjct: 2065 G 2065
Score = 45.8 bits (107), Expect = 0.001
Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
C +C ++A + C SA GCVC G F CVP C C H LG
Sbjct: 2352 CPVSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVF 2407
Query: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG 5035
PG E + CE C G V Q + C EE LE G
Sbjct: 2408 YPGPECERRCE---CGPGGHVTCQEGA--ACGPHEECRLEDG 2444
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 1807 CPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWP 1865
CP +C ++ C P CP +C+ + C PC GC C G V S G CV
Sbjct: 741 CP-LSCPANSRYELCGPACPTSCNGAAAPSNCSGR-PCVE-GCVCLPGFV-ASGGACVPA 796
Query: 1866 RQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLN 1903
C C G + PGQ + AD +LC RRC N
Sbjct: 797 SSCGCTFQGLQLAPGQEVWAD-ELC------QRRCTCN 827
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 1949 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 2006
Query: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
C CW + + AG C+ C G L CT C GLLP
Sbjct: 2007 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 2060
Score = 45.1 bits (105), Expect = 0.002
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 15/106 (14%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
CPA Y C P CP SC C C EGC C G ACV C
Sbjct: 745 CPANSRYELCGPA--CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSC--- 799
Query: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
G T G L PG E+ + + + C C+ A +++C
Sbjct: 800 -------GCTF--QGLQLAPGQEVWADELCQRRC-TCNGATHQVTC 835
Score = 45.1 bits (105), Expect = 0.002
Identities = 37/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%)
Query: 1786 CAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCG 1844
C A G + R CP + PN+ ++ CA C L C +S PP G
Sbjct: 1512 CQAAGGHVEPWRTETFCPMECPPNSH------YELCADTCSLGCSALSA----PPQCQDG 1561
Query: 1845 -SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD-C-QLCICQDGRPRRCR 1901
+ GC C G + + CV +QC C +G Y P Q + D C Q C C G+ C+
Sbjct: 1562 CAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
Score = 45.1 bits (105), Expect = 0.002
Identities = 51/222 (22%), Positives = 68/222 (30%), Gaps = 73/222 (32%)
Query: 4357 CYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAG-----APCTRL---DG 4408
C S PCP C +Q+ GP + G + APC L
Sbjct: 2245 CVSKPCPSPCT---------------PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 2289
Query: 4409 HFRPCLISNCS----EDSCTPPFEFHACGSPCAGL--------------CATHLSHQLCQ 4450
+F+ CL+ C P + AG C H ++LC
Sbjct: 2290 YFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCG 2349
Query: 4451 DLPP---------------CQPGCYCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAP 4494
D P C+ GC C G + C+P +C C H G P
Sbjct: 2350 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYP 2409
Query: 4495 GDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGP 4536
G + + CEC G H T Q E + CGP
Sbjct: 2410 GPECE---RRCECGPGG-HVTCQ------------EGAACGP 2435
Score = 44.7 bits (104), Expect = 0.002
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 14/96 (14%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC-----GLPSANA 4732
C + CP SC L C + CR GC C G ++ CVP+ C C P
Sbjct: 2348 CGDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 2406
Query: 4733 SWELAPAQAVQLDCQ-----NCTCVNESLVCPHQEC 4763
+ P + C+ + TC + PH+EC
Sbjct: 2407 FY---PGPECERRCECGPGGHVTCQEGAACGPHEEC 2439
Score = 44.3 bits (103), Expect = 0.003
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 1940 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 1992
Query: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 1993 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2049
Query: 4763 C 4763
C
Sbjct: 2050 C 2050
Score = 44.3 bits (103), Expect = 0.003
Identities = 148/650 (22%), Positives = 200/650 (30%), Gaps = 152/650 (23%)
Query: 3078 GLQPC----AGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH---PGCHCPSGML 3130
G Q C + P P C ++Q + GP +C +SA G CH P G L
Sbjct: 2238 GAQGCGECVSKPCPSPCTPEQQ--ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2295
Query: 3131 LLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWT 3190
L C +GH PG C V+ +A C + GE W
Sbjct: 2296 L----------DACQVQGH---PGGL-------CPAVATYVAACQAAGAQLGE-----WR 2330
Query: 3191 PWSQCSASCGPARCHRHRFCARS-PSAVPSTVAPLPLPATPTPLC---SGPEAEEEPCLL 3246
C C PA H + C S P + PS AP + C +G + C+
Sbjct: 2331 RPDFCPLQC-PAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVP 2388
Query: 3247 QG---CDRAGGWGPWG----PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC---EGPRA 3296
G C G + P G P C R C G C + G + C +G +A
Sbjct: 2389 VGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHV-TCQEGAACGPHEECRLEDGVQA 2447
Query: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQ-----V 3351
C A C C A G Y R D C + C+ PG V
Sbjct: 2448 ----CHATGCG--RCLANGGIHYITLDG---RVYDLHGSCSYVLAQVCHPKPGDEDFSIV 2498
Query: 3352 LSSNGAICVQPGHCSC----LDLLTGQRHH-PGARLARPDGCNHC-TCLEGR---LNCT- 3401
L N A +Q + + L GQ+ G +A P EGR L T
Sbjct: 2499 LEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK 2558
Query: 3402 --------------DLPCPVPGGWCP--------WSE-WTMCSQPCRGQTRSRSRACACP 3438
+P P G C WS+ + + + + A P
Sbjct: 2559 GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAP 2618
Query: 3439 TPQHGGAPCTGEAG-------EAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQS 3491
G G G E EAC P GP++ C L S
Sbjct: 2619 GSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN--------PQGPFATCQAVLSPS 2670
Query: 3492 HRSRACSRPPTPEGG-------------RPCPGNHTQSRPCQENSTQCTDCGGGQSLHPC 3538
R C + G C +P + +S C C
Sbjct: 2671 EYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSIC 2730
Query: 3539 GQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPE 3598
+ C SC LS + C + C C C L G+C+P C C + +P
Sbjct: 2731 TRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTH--NGRYLPV 2785
Query: 3599 NQSRSAGSRFSSWESLEPGEVVTGPC-DNCTCVAGI-LQCQEVPDCPDPG 3646
N S ++T C + C+C + L CQ CP PG
Sbjct: 2786 NSS-----------------LLTSDCSERCSCSSSSGLTCQ-AAGCP-PG 2816
Score = 43.9 bits (102), Expect = 0.004
Identities = 48/189 (25%), Positives = 63/189 (33%), Gaps = 42/189 (22%)
Query: 3599 NQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP-----------GV 3647
+Q+ +A +SWE + P P C G C CP G+
Sbjct: 1407 SQAGNANEFGNSWEEVVPDSPCLPPTP---CPPGSEDCIPSHKCPPELEKKYQKEEFCGL 1463
Query: 3648 WSS-WGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCST-----QVCREAG----- 3696
SS GP C L+ C C G S CS C+ AG
Sbjct: 1464 LSSPTGPLSSCHKLVDPQGPLKD--CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEP 1521
Query: 3697 ----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA 3746
CP Y C + C C+ ++ C +GC EGC C G + A
Sbjct: 1522 WRTETFCPMECPPNSHYELC--ADTCSLGCSALSAPPQC-QDGCAEGCQCDSGFLYNGQA 1578
Query: 3747 CV--QECPC 3753
CV Q+C C
Sbjct: 1579 CVPIQQCGC 1587
Score = 43.1 bits (100), Expect = 0.007
Identities = 33/133 (24%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 2854 GRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQ 2912
G C +LA C + ++ C CP + + + CP C
Sbjct: 1103 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY------GCPLSCGDL 1156
Query: 2913 GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASG-AMARLDSCNN-CTC 2970
C C GC C G L SCLP + C C G + G C++ C C
Sbjct: 1157 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
Query: 2971 VSGKM-ACTSERC 2982
G + +C S C
Sbjct: 1217 QEGGLVSCESSSC 1229
Score = 42.7 bits (99), Expect = 0.009
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 14/105 (13%)
Query: 3486 MCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRS 3545
+C G S ++AC G P N S C CG CP S
Sbjct: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLS------------CPANSRYELCGPACPTS 761
Query: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ 3590
C + S C C C C G ++ G CVP + C C +Q
Sbjct: 762 CNGAAAPSNCSGRP--CVEGCVCLPGFVASGGACVPASSCGCTFQ 804
Score = 42.7 bits (99), Expect = 0.009
Identities = 58/252 (23%), Positives = 84/252 (33%), Gaps = 63/252 (25%)
Query: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 2220 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 2279
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
P G+ ++ C + C PG + C+ AG
Sbjct: 2280 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLGEW 2329
Query: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 2330 RRPDFCPLQCPAHSHYELC--GDSCPVSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 2386
Query: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSC---GNCSCAHGKL 3800
V C G PLG PG E + R C G+ +C G
Sbjct: 2387 VPVGQC----------GCLHDGRYYPLGEVFYPGPECER----RCECGPGGHVTCQEGAA 2432
Query: 3801 SCSLDDCFEADG 3812
++C DG
Sbjct: 2433 CGPHEECRLEDG 2444
Score = 42.0 bits (97), Expect = 0.016
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 6/84 (7%)
Query: 4642 AEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCR 4701
A G PW E CP + C+ CP SC DL C C
Sbjct: 1114 AACQAAGATVHPWRSEELCPLSCPPHSHYEA-----CSYGCPLSCGDLPVPGGC-GSECH 1167
Query: 4702 PGCRCPPGQLVQDGRCVPISSCRC 4725
GC C G + C+P++SC C
Sbjct: 1168 EGCVCDEGFALSGESCLPLASCGC 1191
Score = 41.6 bits (96), Expect = 0.021
Identities = 73/320 (22%), Positives = 95/320 (29%), Gaps = 94/320 (29%)
Query: 3057 GGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGPASCAELSAPRGT 3115
GGG S E + G C PG CP+ D Q C L+ P+G
Sbjct: 1018 GGGQAANALAFGNSWQEETRPG---CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
Query: 3116 NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCS 3175
+ CH P G + C ++ L P S + C ++ A C
Sbjct: 1075 FRECHSKLD-PQGAVR-----------DCVYDRCLLPGQSGPL-----CDALATYAAACQ 1117
Query: 3176 SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235
+ T PW C SC P H P + LP+P
Sbjct: 1118 A-----AGATVHPWRSEELCPLSCPP-----HSHYEACSYGCPLSCGDLPVP-------- 1159
Query: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPR 3295
GG G S C C CD EG
Sbjct: 1160 -----------------GGCG-----SECHEGC---------VCD-----------EGFA 1177
Query: 3296 AQGEVCQALPCPVTNCTAIEGAEYSPCGP---PCPRSCDDLVHC----VWRCQPGCYCPP 3348
GE C P+ +C + Y P G P P CD L HC + C+ P
Sbjct: 1178 LSGESC----LPLASCGCVHQGTYHPPGQTFYPGP-GCDSLCHCQEGGLVSCESSSCGPH 1232
Query: 3349 GQVLSSNGAI-CVQPGHCSC 3367
S G++ CV G +C
Sbjct: 1233 EACQPSGGSLGCVAVGSSTC 1252
Score = 41.6 bits (96), Expect = 0.021
Identities = 38/140 (27%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 4933 APGELGLCEQTCL-EMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGR 4991
A +C +TC A + C++ GC C SQ G C+P C C H GR
Sbjct: 2723 AHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ-GVCIPVQDCGCTHNGR 2781
Query: 4992 PHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSP 5051
+LP S L S C++ CS C+ + + C P
Sbjct: 2782 -YLP-------VNSSLLTSD---CSERCS---CSSSSGLTCQAAGCPP----------GR 2817
Query: 5052 SCQLLTELRN--FTKGTCYL 5069
C++ E RN T+G C L
Sbjct: 2818 VCEVKAEARNCWATRGLCVL 2837
Score = 41.2 bits (95), Expect = 0.027
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 1952 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2011
Query: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
G + GS CS W C G S C PA
Sbjct: 2012 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 2049
Query: 3204 CHRHRFCARSPS 3215
C C PS
Sbjct: 2050 CGLGEVCGLLPS 2061
Score = 41.2 bits (95), Expect = 0.027
Identities = 34/111 (30%), Positives = 43/111 (38%), Gaps = 12/111 (10%)
Query: 3306 CPVTNCTAIEGAEYSPCGPPCPRSC---DDLVHCVWRCQPGCYCPPGQVLSSNGAICVQP 3362
CP+ +C A + YS C C SC L C RC GC C +LS +C+
Sbjct: 2717 CPL-HCPA--HSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVCIPV 2771
Query: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPGGWC 3412
C C G+ + L D C+C L C CP PG C
Sbjct: 2772 QDCGCTH--NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP-PGRVC 2819
Score = 40.8 bits (94), Expect = 0.035
Identities = 172/773 (22%), Positives = 231/773 (29%), Gaps = 192/773 (24%)
Query: 2631 LVPPCPPSCLDPKANRSCSGHCVEGCRCPP------------GLLLHDTRCLPLSECPCL 2678
+VP P CL P S C+ +CPP GLL T PLS C L
Sbjct: 1422 VVPDSP--CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG--PLSSCHKL 1477
Query: 2679 VGEELKWPGVSFLL----GNCSQCVCEKGELL---CQPGG-----------CPLPCGWSA 2720
V + F L GN S +C CQ G CP+ C +
Sbjct: 1478 VDPQGPLKDCIFDLCLGGGNLS-ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPN- 1535
Query: 2721 WSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCE-GDRQELQGCHTV--CGTEVFG--W 2775
S + C +C G A P G C+ G Q C + CG G +
Sbjct: 1536 -SHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYY 1594
Query: 2776 TPWTSW--SSCSQSCLAPGGGPGWRSRSRLC-------PSPGDSSCPGDATQEEPCSPPV 2826
P + +C Q C G G + C PS G SC ++PC
Sbjct: 1595 EPEQTVLIDNCRQQCTCHAG-KGMVCQEHSCKPGQVCQPSGGILSC----VTKDPCHGVT 1649
Query: 2827 CPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQC 2886
C P TC G+ + GD PH + D
Sbjct: 1650 C---------RPQETCKEQGGQGVCLPNYEATCWLWGD-----PHYHSFDGRK------- 1688
Query: 2887 PENMLFRSAEQCHQEGGPCPRLCLTQG-PGIECTGFCAPGCTCPPGLFLHNASCLPRSQC 2945
G C + T G PG+ G T + A R
Sbjct: 1689 ------------FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVT 1736
Query: 2946 PCQLHGQLYA-SGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVG 3004
L + + ++ C N + ++ R VA G S L + V
Sbjct: 1737 VAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL--VADFGLQVS 1794
Query: 3005 IRRRFRAGTAPPAAFGGAEC-------QGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCG 3057
+R P+++ GA C + P + F P G P S+P
Sbjct: 1795 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVF--------PNGTLAP----SIPIW 1842
Query: 3058 GGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAEL-SAPRGTN 3116
GG S + C G P CP D+ L+ +GP C L S G
Sbjct: 1843 GG--------SWRAPGWDPLCWDECRGSCP-TCPEDR--LEQYEGPGFCGPLASGTGGPF 1891
Query: 3117 QTCHPGCHCP-----SGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLI 3171
TCH H P G +L +VC+ D C ++ +
Sbjct: 1892 TTCH--AHVPPESFFKGCVL--DVCMGGGDRDIL------------------CKALASYV 1929
Query: 3172 ANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPT 3231
A C + W C +C P H P++ PS P P T
Sbjct: 1930 AACQA-----AGVVIEDWRAQVGCEITC-PENSHYEVCGPPCPASCPS-----PAPLTTP 1978
Query: 3232 PLCSGPEAEEEPC---LLQGCDRA----GGWGPWGPWSH------------CSRSCGGGL 3272
+C GP E C + DR G G W ++ CS+ C G
Sbjct: 1979 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 2038
Query: 3273 RSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
+ C P GLG EVC LP C + AE G P
Sbjct: 2039 GGGSLVCT-PASCGLG----------EVCGLLPSGQHGCQPVSTAECQAWGDP 2080
Score = 40.4 bits (93), Expect = 0.046
Identities = 53/203 (26%), Positives = 66/203 (32%), Gaps = 50/203 (24%)
Query: 3477 PWGPWSPCDMCLGQSHRSRAC--SRPPTP-EGGRPCPGNHTQSRPCQ---------ENST 3524
P GP+ C L R C R P + G C T + CQ +
Sbjct: 1071 PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEE 1130
Query: 3525 QCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVG--CQPTCGCPLGQLSQDGLCVP 3581
C C C CP SC DL PG G C C C G C+P
Sbjct: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPV-----PGGCGSECHEGCVCDEGFALSGESCLP 1185
Query: 3582 PAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTC-VAGILQCQEV 3639
A C C +Q G+ ++ PG CD+ C C G++ C+
Sbjct: 1186 LASCGCVHQ--------------GTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES- 1226
Query: 3640 PDCPDPGVWSSWGPWEDCSVSCG 3662
SS GP E C S G
Sbjct: 1227 ---------SSCGPHEACQPSGG 1240
Score = 40.0 bits (92), Expect = 0.060
Identities = 60/231 (25%), Positives = 79/231 (34%), Gaps = 52/231 (22%)
Query: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 2234 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 2284
Query: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
+ + PGGL CP A C +G + + P CP
Sbjct: 2285 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLGEWRRPDFCP 2336
Query: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
L C S C P P GC C G VL + CV QC CL
Sbjct: 2337 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 2395
Query: 1872 VDGARY------WPGQRIKADCQL-----CICQDGRPRRCRLNPDCAVDCG 1911
DG Y +PG + C+ CQ+G C + +C ++ G
Sbjct: 2396 HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG--AACGPHEECRLEDG 2444
Score = 40.0 bits (92), Expect = 0.060
Identities = 29/100 (29%), Positives = 34/100 (34%), Gaps = 10/100 (10%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C + C C G CA C C GC C L G CIP ++C C H
Sbjct: 2721 CPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDCGCTH 2778
Query: 4483 TSA-AGAGMTLAPGDRLQLGCKE-CECRRGE-LHCTSQGC 4519
+L D C E C C L C + GC
Sbjct: 2779 NGRYLPVNSSLLTSD-----CSERCSCSSSSGLTCQAAGC 2813
Score = 39.7 bits (91), Expect = 0.078
Identities = 62/253 (24%), Positives = 81/253 (32%), Gaps = 54/253 (21%)
Query: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
G + PS G G+W W P W C +C + R + C PL
Sbjct: 1833 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA----SGT 1887
Query: 1733 PGP-----EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCA 1787
GP H F C +D C G R C + + C
Sbjct: 1888 GGPFTTCHAHVPPESFFKGCVLD--------------VCMGGGDRDILCKALASYVAACQ 1933
Query: 1788 ALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCG 1844
A + R Q GC TC ++ C P CP +C +T P + PC
Sbjct: 1934 AAGVVIEDWRA-----QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCV 1986
Query: 1845 SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------ 1895
GC C G VL ++ C C +G + G AD Q C C G
Sbjct: 1987 E-GCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 2045
Query: 1896 RPRRCRLNPDCAV 1908
P C L C +
Sbjct: 2046 TPASCGLGEVCGL 2058
Score = 38.9 bits (89), Expect = 0.13
Identities = 31/101 (30%), Positives = 35/101 (34%), Gaps = 8/101 (7%)
Query: 4940 CEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
C C L C S GCVC G F C+P C C H G H PG
Sbjct: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQT 1203
Query: 4999 WQ--EACES-CLCLSGRPVCTQHCSPLTCAQGEEMVLEPGS 5036
+ C+S C C G V C +C E GS
Sbjct: 1204 FYPGPGCDSLCHCQEGGLV---SCESSSCGPHEACQPSGGS 1241
Score = 37.4 bits (85), Expect = 0.39
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 27/124 (21%)
Query: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
GP+ C E R +C C ++ C T C+ AG
Sbjct: 2658 GPFATCQAVLSPSEYFR--QCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS 2715
Query: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQ 3749
CPA Y C C SCA ++ GC + C EGC C + + C VQ
Sbjct: 2716 FCPLHCPAHSHYSICT--RTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQ 2772
Query: 3750 ECPC 3753
+C C
Sbjct: 2773 DCGC 2776
Score = 34.3 bits (77), Expect = 3.3
Identities = 35/150 (23%), Positives = 45/150 (30%), Gaps = 33/150 (22%)
Query: 3460 REACPSYATCPVDG-------------AWGPWGPWSPC---------------DMCLGQS 3491
R +CP TCP D A G GP++ C D+C+G
Sbjct: 1860 RGSCP---TCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 1916
Query: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
R C + G + Q C CG PCP SC +P
Sbjct: 1917 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGPPCPASCPSPAP 1974
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
+ C C C G + CVP
Sbjct: 1975 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 2004
Score = 32.7 bits (73), Expect = 9.6
Identities = 39/143 (27%), Positives = 47/143 (32%), Gaps = 26/143 (18%)
Query: 3628 TCVAGILQCQEVPDCPDPGVWSSWGPWEDC---------------SVSCGGGEQ---LRS 3669
TC L+ E P P + GP+ C V GGG++ ++
Sbjct: 1865 TCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKA 1924
Query: 3670 RRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSC---AHVTQQVGCF 3726
C QV E CP Y C P CP SC A +T C
Sbjct: 1925 LASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPP--CPASCPSPAPLTTPAVC- 1981
Query: 3727 SEG-CEEGCHCPEGTFQHRLACV 3748
EG C EGC C G CV
Sbjct: 1982 -EGPCVEGCQCDAGFVLSADRCV 2003
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 401 bits (1030), Expect = e-110
Identities = 393/1475 (26%), Positives = 548/1475 (37%), Gaps = 288/1475 (19%)
Query: 73 LCPIYKPPETRPAKWNRTVRTCC-----PGWGGAHCTEALAKASPEGHCFAMWQCQLQAG 127
LCP+ PP + + C PG G+ C E EG + C
Sbjct: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGESCL---- 1184
Query: 128 SANASAGSLEECCARPWGQSWWDGSSQACRS---CSSRHLPGSASSPA----LLQPLAGA 180
AS G + + P GQ+++ G C S C L SS QP G+
Sbjct: 1185 -PLASCGCVHQGTYHPPGQTFYPGPG--CDSLCHCQEGGLVSCESSSCGPHEACQPSGGS 1241
Query: 181 VGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP 240
+G + S+TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 1242 LGCV----AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH-------- 1289
Query: 241 QPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL--------------- 285
R + E V G VSV + + ++ L QW
Sbjct: 1290 ------RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLA 1343
Query: 286 ---------GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFME 336
G +V+ G+ V D + ++V + Q GLCG YNG P+DDF +
Sbjct: 1344 NGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQK 1403
Query: 337 PGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQG---CDPLGLIDADVEPGHLRAEAQDV 393
P G A A FGNSW +S CL G C P ++E + + ++
Sbjct: 1404 PNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEK---KYQKEEF 1460
Query: 394 CHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACA 451
C L GP CH V P + C+F C G G +C+ +YV AC
Sbjct: 1461 CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQ 1513
Query: 452 RRHIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRG 510
H+ WR FC CP Y C C C A+ + C++ C GC+C G
Sbjct: 1514 AAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQ--CQDGCAEGCQCDSG 1571
Query: 511 LFWNGTLCVPAAHCPCYYCRQRYVPGDTV--------------------------RQLCN 544
+NG CVP C CY+ Y P TV Q+C
Sbjct: 1572 FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQ 1631
Query: 545 P------CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSF 582
P CV +D + Q +C A C + GD HY +FDGR + F
Sbjct: 1632 PSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDF 1691
Query: 583 WG-------GQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLR--DS 633
G GC Q + ++ A S + ++V+ T+I + +
Sbjct: 1692 QGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEI 1751
Query: 634 GAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQ 692
G V VNG LP A+G +SV + +S LL+ G QV + + V +TL +
Sbjct: 1752 GKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYHGA 1810
Query: 693 VQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSALLS 743
V GLCG +N +D + P G + SI + ++ G +G CP+
Sbjct: 1811 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT------- 1863
Query: 744 PCTTHSQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPV 800
C C L F CH V E F+ C+ VC D LC
Sbjct: 1864 -CPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKA 1922
Query: 801 LSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGE----LGS 855
L++Y C G WR Q C + CP Y C C C P G
Sbjct: 1923 LASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGP 1982
Query: 856 CVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTAR 915
CV GC C G + + +CVP + N C C G +
Sbjct: 1983 CVEGCQCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY----- 2015
Query: 916 HCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCP 975
H F +A G C C C G VC P + L E C L P
Sbjct: 2016 HEAGSEF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GLLP 2058
Query: 976 CRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGA 1035
SGQ H + CQA G PHYVT DG F + G
Sbjct: 2059 ---SGQ----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGT 2093
Query: 1036 CEYLLVREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAVTV 1087
CEYLL G FTV+ N G+ ++ T+++ +++ + R + V
Sbjct: 2094 CEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQV 2153
Query: 1088 NGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCG 1147
+GV VT P L +G ++++T GL+L +DG + V +++ + G + GLCG
Sbjct: 2154 DGVFVTLP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCG 2212
Query: 1148 DFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGA 1207
+++ D ++DL++ G +P + +P P PCT + CG
Sbjct: 2213 NYNQDPADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDACGV 2268
Query: 1208 LLQ---PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR 1264
+ PL CH VPP Q+++ CL DAC G LC A+ATY C G +R
Sbjct: 2269 ISATDGPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLR 2325
Query: 1265 -WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGG 1323
WR + C QC YE CG +CP +C G C+ AC EGC C G +L G
Sbjct: 2326 EWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG--CE-SACREGCVCDAGFVLSGD 2382
Query: 1324 ACLEPASCPCEWGRNSFPPGSVLQKDCG---NCTCQEGQWHCGGDGGHCEELVPACAEGE 1380
C+ C C +P G G C C+EG GE
Sbjct: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG--------------------GE 2422
Query: 1381 ALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPG 1415
C E C PH + C GC A G
Sbjct: 2423 VSC-EPSSCGPH-------ETCRPSGGSLGCVAVG 2449
Score = 400 bits (1027), Expect = e-110
Identities = 387/1469 (26%), Positives = 539/1469 (36%), Gaps = 267/1469 (18%)
Query: 71 PGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGH-CFAMWQCQLQAGSA 129
P CP P + + CP E A EG C A +
Sbjct: 3531 PDFCPFQCPAHSHYELCGDSCPGSCPSLSAP---EGCESACREGCVCDAGFVLSGDTCVP 3587
Query: 130 NASAGSLEECCARPWGQSWWDGSS--QACRSCSSRHL---PGSASSPALLQPLAGAVGQL 184
G L + P GQ+++ G CR + P S +P G++G +
Sbjct: 3588 VGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV 3647
Query: 185 WSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGH 244
S TC + HY TFDG + F+G C Y+LA + +H
Sbjct: 3648 ----AVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLH------------ 3691
Query: 245 CQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL------------------- 285
R + E V G VSV + + ++ L QW
Sbjct: 3692 --RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQI 3749
Query: 286 -----GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGG 340
G +V+ G+ V D + ++V + GLCG YNG P+DDF +P G
Sbjct: 3750 RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGS 3809
Query: 341 LAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHL--RAEAQDVCHQLL 398
A A FGNSW +S CL G G I +D P L + + ++ C L
Sbjct: 3810 QAGNANEFGNSWEEVVPDSPCLPPPTCPPG--SAGCIPSDKCPPELEKKYQKEEFCGLLS 3867
Query: 399 E--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
GP CH V P + C+F C G G +C+ +YV AC H
Sbjct: 3868 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQAAGGH 3920
Query: 457 IR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNG 515
+ WR FC CP Y C C C A+ + C + C GC+C G +NG
Sbjct: 3921 VEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ--CPDGCAEGCQCDSGFLYNG 3978
Query: 516 TLCVPAAHCPCYYCRQRYVPGDTV--------------------------RQLCNP---- 545
CVP C CY+ Y P TV Q+C P
Sbjct: 3979 QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGI 4038
Query: 546 --CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSFWG--- 584
CV +D + Q +C A C + GD HY +FDGR + F G
Sbjct: 4039 LSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 4098
Query: 585 ----GQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLV 638
GC Q + ++ A S + ++V+ T+I + + G V V
Sbjct: 4099 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 4158
Query: 639 NGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLC 697
NG LP A+G +SV + +S LL+ G QV + + V +TL + V GLC
Sbjct: 4159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYHGAVCGLC 4217
Query: 698 GTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSALLSPCTTH 748
G +N +D + P G + SI + ++ G +G CP+ C
Sbjct: 4218 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT--------CPED 4269
Query: 749 SQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYA 805
C L S F CH V E F+ C+ VC D LC L++Y
Sbjct: 4270 RLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYV 4329
Query: 806 RRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGE----LGSCVAGC 860
C G WR Q C + CP Y C P C C P G CV GC
Sbjct: 4330 AACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC 4389
Query: 861 NCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQ 920
C G + + +CVP + N C C G + H
Sbjct: 4390 QCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY-----HEAGS 4422
Query: 921 AFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG 980
F +A G C C C G VC P + L E C L P SG
Sbjct: 4423 EF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GLLP---SG 4462
Query: 981 QWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLL 1040
Q H + CQA G PHYVT DG F + G CEYLL
Sbjct: 4463 Q----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 4500
Query: 1041 VREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAVTVNGVSV 1092
G FTV+ N G+ ++ T+++ +++ + R + V+GV V
Sbjct: 4501 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 4560
Query: 1093 TPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGD 1152
P L +G ++++T GL+L +DG + V +++ + + GLCG+++ D
Sbjct: 4561 ALP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQD 4619
Query: 1153 ASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQ-- 1210
++DL++ G +P + +P P PCT + CG +
Sbjct: 4620 PADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDACGVISATD 4675
Query: 1211 -PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV-RWRSQ 1268
PL CH VPP Q+++ CL DAC G LC A+ATY C G + WR
Sbjct: 4676 GPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRP 4732
Query: 1269 ELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEP 1328
+ C LQC YE CG +CP +C G C+ AC EGC C G +L G C+
Sbjct: 4733 DFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG--CE-SACREGCVCDAGFVLSGDTCVPV 4789
Query: 1329 ASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGH 1388
C C +P G V G CE G CQE
Sbjct: 4790 GQCGCLHDGRYYPLGEVFY-----------------PGPECERRCECGPGGHVTCQEGAA 4832
Query: 1389 CVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417
C PH ++C + C A GCG
Sbjct: 4833 CGPH-------EECRLEDGVQACHATGCG 4854
Score = 392 bits (1007), Expect = e-108
Identities = 391/1488 (26%), Positives = 545/1488 (36%), Gaps = 280/1488 (18%)
Query: 71 PGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGH-CFAMWQCQLQAGSA 129
P CP P + + CP E A EG C A +
Sbjct: 2330 PDFCPFQCPAHSHYELCGDSCPGSCPSLSAP---EGCESACREGCVCDAGFVLSGDTCVP 2386
Query: 130 NASAGSLEECCARPWGQSWWDGSS--QACRSCSSRHL---PGSASSPALLQPLAGAVGQL 184
G L + P GQ+++ G CR + P S +P G++G +
Sbjct: 2387 VGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV 2446
Query: 185 WSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGH 244
S TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 2447 ----AVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH------------ 2490
Query: 245 CQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL------------------- 285
R + E V G VSV + + ++ L QW
Sbjct: 2491 --RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQI 2548
Query: 286 -----GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGG 340
G +V+ G+ V D + ++V + GLCG YNG P+DDF +P G
Sbjct: 2549 RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGS 2608
Query: 341 LAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHL--RAEAQDVCHQLL 398
A A FGNSW +S CL G + G I ++ P L + + ++ C L
Sbjct: 2609 QAGNANEFGNSWEEVVPDSPCLPPPTCPPGSE--GCIPSEECPPELEKKYQKEEFCGLLS 2666
Query: 399 E--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
GP CH V P + C+F C G G +C+ +YV AC
Sbjct: 2667 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQAAGGQ 2719
Query: 457 IR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNG 515
+ WR FC CP Y C C C A+ + C + C GC+C G +NG
Sbjct: 2720 VEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ--CPDGCAEGCQCDSGFLYNG 2777
Query: 516 TLCVPAAHCPCYYCRQRYVPGDTV--------------------------RQLCNP---- 545
CVP C CY+ Y P TV Q+C P
Sbjct: 2778 QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGI 2837
Query: 546 --CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSFWG--- 584
CV +D + Q +C A C + GD HY +FDGR + F G
Sbjct: 2838 LSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 2897
Query: 585 ----GQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLV 638
GC Q + ++ A S + ++V+ T+I + + G V V
Sbjct: 2898 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 2957
Query: 639 NGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLC 697
NG LP A+G +SV + +S LL+ G QV + + V +TL + V GLC
Sbjct: 2958 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYHGAVCGLC 3016
Query: 698 GTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSALLSPCTTH 748
G +N +D + P G + SI + ++ G +G CP+ C
Sbjct: 3017 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT--------CPED 3068
Query: 749 SQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYA 805
C L F CH V E F+ C+ VC D LC L++Y
Sbjct: 3069 RLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYV 3128
Query: 806 RRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGE----LGSCVAGC 860
C G WR Q C + CP Y C P C C P G CV GC
Sbjct: 3129 AACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC 3188
Query: 861 NCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQ 920
C G + + +CVP + N C C G + H
Sbjct: 3189 QCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY-----HEAGS 3221
Query: 921 AFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG 980
F +A G C C C G VC P + L E C L P SG
Sbjct: 3222 EF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GLLP---SG 3261
Query: 981 QWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLL 1040
Q H + CQA G PHYVT DG F + G CEYLL
Sbjct: 3262 Q----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 3299
Query: 1041 VREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAVTVNGVSV 1092
G FTV+ N G+ ++ T+++ +++ + R + V+GV V
Sbjct: 3300 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 3359
Query: 1093 TPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGD 1152
T P L +G ++++T GL+L +DG + V +++ + G + GLCG+++ D
Sbjct: 3360 TLP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQD 3418
Query: 1153 ASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQ-- 1210
++DL++ G +P + +P P PCT + CG +
Sbjct: 3419 PADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDACGVISATD 3474
Query: 1211 -PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQ 1268
PL CH VPP Q+++ CL DAC G LC A+ATY C G +R WR
Sbjct: 3475 GPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRP 3531
Query: 1269 ELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEP 1328
+ C QC YE CG +CP +C G C+ AC EGC C G +L G C+
Sbjct: 3532 DFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG--CE-SACREGCVCDAGFVLSGDTCVPV 3588
Query: 1329 ASCPCEWGRNSFPPGSVLQKDCG---NCTCQEGQWHCGGDGGHCEELVPACAEGEALCQE 1385
C C +P G G C C+EG GE C E
Sbjct: 3589 GQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG--------------------GEVSC-E 3627
Query: 1386 NGHCVPHGWLCDNQDDCGDGSDEEGCAAPG------CGEGQMTCSSGH 1427
C PH + C GC A G G+ T GH
Sbjct: 3628 PSSCGPH-------ETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGH 3668
Score = 389 bits (999), Expect = e-107
Identities = 363/1317 (27%), Positives = 514/1317 (39%), Gaps = 217/1317 (16%)
Query: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVT-M 250
+A C + HY TFDGR Y +G C+Y + + + + +RV+ +
Sbjct: 469 TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
Query: 251 GPEEVLIQAGNVSV-KGQ----LVPEGQSWLLHGLSLQWL-----GDWLVLSGGLGVVVR 300
G V + +VS+ +G+ LV +S L LS L G V+ G+VV
Sbjct: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
Query: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
D +++S+ Q GLCG YNG P DDF+ P G LA A F +SW+L +
Sbjct: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
Query: 361 CLDAVEVAQGCDPLGLIDADVEPGHLR-AEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
C D + C PG + E +C L L+GPF CH + P + E
Sbjct: 649 CEDGCQ--NNCPA-------CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
Query: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYS 476
C++ C G + ++C ++Y QAC I + WR P C CP Y
Sbjct: 700 CVYDLCVVG-------GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYE 752
Query: 477 DCVSLCPPSCEAVGQGEEESCR-EECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVP 535
C CP SC G +C CV GC C G +G CVPA+ C C + + P
Sbjct: 753 LCGPACPTSCN--GAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAP 810
Query: 536 GDTV--------RQLCN----PCVCRDGRWHCAQALCPAE-------------CAVGGDG 570
G V R CN CRD + A C + C GD
Sbjct: 811 GQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDP 870
Query: 571 HYLTFDGRSYSFWGGQGCRYSLVQDYVKG------QLLILLEHGACDAGSCLHAISVSLE 624
HY++FDGR + F G C Y LV + ++L+ EH S A+ V
Sbjct: 871 HYVSFDGRRFDFMG--TCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEAR 928
Query: 625 DTHIQLRDS--GAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVA 681
+ +R G VLV+ LP+ A+G + V R ++ G V + + V
Sbjct: 929 GVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVT 988
Query: 682 YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ--------VAGKGR 733
+ +A + GLCG F + DD G + AF + +Q G
Sbjct: 989 -AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGD 1047
Query: 734 CPSEDSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCD 791
CP DS + + ++ C IL F+ECH +D + C+ C
Sbjct: 1048 CPKLDSLVAQQLQSKNE--------CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
Query: 792 PGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---P 847
S LC L+ YA C GA+ PWR++ LCP+ CP Y C+ C CG P
Sbjct: 1100 GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVP 1159
Query: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM--KECNR-CIC 904
CG C GC C G E C+P + C C + PG C+ C C
Sbjct: 1160 GGCG--SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
Query: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
QE GL +C + C C P+G + GCV +
Sbjct: 1217 QEGGLVSCESSSCGPHEACQ-----------------------PSGGSLGCVAVGSST-- 1251
Query: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
C+ SG PHY T
Sbjct: 1252 -----------CQASGD--------------------------------------PHYTT 1262
Query: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
Query: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 1323 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 1382
Query: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--------LSPLCPEPGD---L 1187
++ GLCG+++GD +D + G A +SW L P PG +
Sbjct: 1383 YQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCI 1442
Query: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
P H C + CG L P L CH V PQ + C++D C GG+
Sbjct: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 1500
Query: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHC 1303
LCS I Y C G HV WR++ C ++C YE C TC C P C
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP--QC 1558
Query: 1304 QVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQEGQWH 1361
Q C EGC C G L +G AC+ C C G P +VL +C CTC G+
Sbjct: 1559 Q-DGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK-- 1615
Query: 1362 CGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEEGC 1411
G C+E +C G+ +CQ +G CV HG C Q+ C + + C
Sbjct: 1616 ----GMVCQE--HSCKPGQ-VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
Score = 387 bits (994), Expect = e-106
Identities = 399/1449 (27%), Positives = 546/1449 (37%), Gaps = 248/1449 (17%)
Query: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
D +++G + P + + SP P CP P T PA P G C
Sbjct: 1939 DWRAQVGCEITCPENSHYEVCGSPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 1991
Query: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 1992 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 2035
Query: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
PG S + P + +G++ QH +P +T C +W HY T DG ++F G
Sbjct: 2036 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQG 2092
Query: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 2093 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 2152
Query: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 2153 VDGVFVTLPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 2204
Query: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV----------- 365
G GLCG YN P DD GG A W++ G++ GC + V
Sbjct: 2205 GSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGECVSKPCPSPCTPE 2255
Query: 366 --EVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
E G D G+I A +GP CH V PA+Y + CL C
Sbjct: 2256 QQESFGGPDACGVISA------------------TDGPLAPCHGLVPPAQYFQGCLLDAC 2297
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLC 482
+G +C A+YV AC +R WR+P FC CP Y C C
Sbjct: 2298 Q-------VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 2350
Query: 483 PPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPG 536
P SC ++ E C C GC C G +G CVP C C Y Q + PG
Sbjct: 2351 PGSCPSL--SAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPG 2408
Query: 537 DTVRQLCNPCVCRD-GRWHCAQALC-PAE------------------CAVGGDGHYLTFD 576
LC CR+ G C + C P E C GD HY TFD
Sbjct: 2409 PGCDSLCR---CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFD 2465
Query: 577 GRSYSFWGGQGCRYSLVQDYVK----GQLLILLEHGACDAG--SCLHAISVSLEDTHIQL 630
GR + F G C Y L Q + +L E+ A G S I+V + + ++L
Sbjct: 2466 GRRFDFMG--TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 2523
Query: 631 RD-SGAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPR 688
V VNG D+ LP + A G + + S ++ G +V + L V +T+
Sbjct: 2524 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR-VTVPGN 2582
Query: 689 HAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ-------VAGKGRCP--SEDS 739
+ + GLCG + + +DDF P G + F + ++ CP SE
Sbjct: 2583 YYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGC 2642
Query: 740 ALLSPCTTHSQRHAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDPGSDCL 797
C ++ E C +L S CH+LVD + C+ +C L
Sbjct: 2643 IPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 2702
Query: 798 CPVLSAYARRC-AQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPEDCGEL 853
C + AY C A G PWRN+T CP+ CP Y CA C C P C +
Sbjct: 2703 CSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD- 2761
Query: 854 GSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCT 913
C GC C G L++ + CVP C C Y P + +
Sbjct: 2762 -GCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLID--------------- 2804
Query: 914 ARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDL 973
+C Q C V + C HSC G VC P +L CV D
Sbjct: 2805 --NCRQQCTCHVGKV-------VVCQ----EHSCKPGQ----VCQPSGGILS--CVNKDP 2845
Query: 974 CPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYP 1033
C G P T +E VC C G PHY +FDG F +
Sbjct: 2846 C----HGVTCRPQETCKEQGGQGVCL--------PNYEATCWLWGDPHYHSFDGRKFDFQ 2893
Query: 1034 GACEYLLVR------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGT--VVHMLRGR 1083
G C Y+L GL FTV+ +N G ++ + + V GT +H
Sbjct: 2894 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 2953
Query: 1084 AVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA 1143
V VNGV P +S+ + LL GL + +D RV V L + G V
Sbjct: 2954 KVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 3013
Query: 1144 GLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPCTMNTHRA 1198
GLCG+ D + +ND G L P+ + SWR PLC + G P C +
Sbjct: 3014 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TCPEDRLEQ 3072
Query: 1199 GWARARCGALLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
CG L FT CHA VPP+ ++ C+ D C GGD + LC A+A+Y
Sbjct: 3073 YEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAA 3130
Query: 1256 CARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314
C G + WR+Q C + C YE CGP CP +C P CVEGC C
Sbjct: 3131 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC 3190
Query: 1315 PEGTLLHGGACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGGDGGHCEE 1371
G +L C+ C C W ++ GS D G C+ QW CG GG
Sbjct: 3191 DAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGPGGGSLVC 3244
Query: 1372 LVPACAEGE 1380
+C GE
Sbjct: 3245 TPASCGLGE 3253
Score = 381 bits (978), Expect = e-104
Identities = 395/1449 (27%), Positives = 543/1449 (37%), Gaps = 248/1449 (17%)
Query: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
D +++G + P + + P P CP P T PA P G C
Sbjct: 3140 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 3192
Query: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 3193 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 3236
Query: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 3237 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 3293
Query: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 3294 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 3353
Query: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 3354 VDGVFVTLPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 3405
Query: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV----------- 365
G GLCG YN P DD GG A W++ G++ GC + V
Sbjct: 3406 GSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGECVSKPCPSPCTPE 3456
Query: 366 --EVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
E G D G+I A +GP CH V PA+Y + CL C
Sbjct: 3457 QQESFGGPDACGVISA------------------TDGPLAPCHGLVPPAQYFQGCLLDAC 3498
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLC 482
+G +C A+YV AC +R WR+P FC CP Y C C
Sbjct: 3499 Q-------VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 3551
Query: 483 PPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPG 536
P SC ++ E C C GC C G +G CVP C C Y Q + PG
Sbjct: 3552 PGSCPSL--SAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPG 3609
Query: 537 DTVRQLCNPCVCRD-GRWHCAQALC-PAE------------------CAVGGDGHYLTFD 576
LC CR+ G C + C P E C GD HY TFD
Sbjct: 3610 PGCDSLCR---CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFD 3666
Query: 577 GRSYSFWGGQGCRYSLVQDYVK----GQLLILLEHGACDAG--SCLHAISVSLEDTHIQL 630
G + F G C Y L Q + +L E+ A G S I+V + + ++L
Sbjct: 3667 GHRFDFMG--TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 3724
Query: 631 RD-SGAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPR 688
V VNG D+ LP + A G + + S ++ G +V + L V +T+
Sbjct: 3725 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR-VTVPGN 3783
Query: 689 HAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ-------VAGKGRCPSEDSAL 741
+ + GLCG + + +DDF P G + F + ++ CP +
Sbjct: 3784 YYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGC 3843
Query: 742 L--SPCTTHSQRHAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDPGSDCL 797
+ C ++ E C +L S CH+LVD + C+ +C L
Sbjct: 3844 IPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 3903
Query: 798 CPVLSAYARRC-AQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPEDCGEL 853
C + AY C A G PWRN+T CP+ CP Y CA C C P C +
Sbjct: 3904 CSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD- 3962
Query: 854 GSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCT 913
C GC C G L++ + CVP C C Y P + +
Sbjct: 3963 -GCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLID--------------- 4005
Query: 914 ARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDL 973
+C Q C V + C HSC G VC P +L CV D
Sbjct: 4006 --NCRQQCTCHVGKV-------VVCQ----EHSCKPGQ----VCQPSGGILS--CVTKDP 4046
Query: 974 CPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYP 1033
C G P T +E VC C G PHY +FDG F +
Sbjct: 4047 C----HGVTCRPQETCKEQGGQGVCL--------PNYEATCWLWGDPHYHSFDGRKFDFQ 4094
Query: 1034 GACEYLLVR------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGT--VVHMLRGR 1083
G C Y+L GL FTV+ +N G ++ + + V GT +H
Sbjct: 4095 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 4154
Query: 1084 AVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA 1143
V VNGV P +S+ + LL GL + +D RV V L + G V
Sbjct: 4155 KVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 4214
Query: 1144 GLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPCTMNTHRA 1198
GLCG+ D + +ND G L P+ + SWR PLC + G P C +
Sbjct: 4215 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TCPEDRLEQ 4273
Query: 1199 GWARARCGALLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
CG L FT CHA VPP+ ++ C+ D C GGD + LC A+A+Y
Sbjct: 4274 YEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAA 4331
Query: 1256 CARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314
C G + WR+Q C + C YE CGP CP +C P CVEGC C
Sbjct: 4332 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC 4391
Query: 1315 PEGTLLHGGACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGGDGGHCEE 1371
G +L C+ C C W ++ GS D G C+ QW CG GG
Sbjct: 4392 DAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGPGGGSLVC 4445
Query: 1372 LVPACAEGE 1380
+C GE
Sbjct: 4446 TPASCGLGE 4454
Score = 351 bits (900), Expect = 1e-95
Identities = 350/1322 (26%), Positives = 491/1322 (37%), Gaps = 229/1322 (17%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH-LTP--------GDRCPQPG 243
ATC W HY +FDGR + F G C Y+LA + LTP P
Sbjct: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 1730
Query: 244 HCQRVTMGPEEVLI-----QAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
+ + VT+ I + G V V G L S +S+ +L G+
Sbjct: 1731 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 1790
Query: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
V D + +++ G GLCG + P +D + P G LA +G SWR PG +
Sbjct: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
Query: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
C D + P ++ PG A GPF CHA V P + + C
Sbjct: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT-----GGPFTTCHAHVPPESFFKGC 1905
Query: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSD 477
+ C G G + +C ASYV AC + I WR CE CP Y
Sbjct: 1906 VLDVCMGG-------GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 1958
Query: 478 CVSLCPPSCEAVGQGEEES-CREECVSGCECPRGLFWNGTLCVPAAH-CPCY-------- 527
C S CP SC + + C CV GC+C G + CVP + C C+
Sbjct: 1959 CGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 2018
Query: 528 --------YCRQ--RYVPGDTVRQLCNPCVCRDGR--------WHCAQALCPAECAVGGD 569
C Q R PG +C P C G H Q + AEC GD
Sbjct: 2019 GSEFWADGTCSQWCRCGPGGG-SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2077
Query: 570 GHYLTFDGRSYSFWGGQGCRYSL----------VQDYVKGQLLILLEHGACDAGSCLHAI 619
HY+T DG ++F G C Y L +++ + + EH A S ++
Sbjct: 2078 PHYVTLDGHRFNFQG--TCEYLLSAPCHGPPLGAENFT---VTVANEHRGSQAVSYTRSV 2132
Query: 620 SVSLEDTHIQL--RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
++ + + + L R + V+G V LP+ + L S A +++ L
Sbjct: 2133 TLQIYNHSLTLSARWPRKLQVDGVFVTLPF-QLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
Query: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGK---GRC 734
D + + +A + GLCG + Q+ DD G + +QV G G C
Sbjct: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 2243
Query: 735 PSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAVCGCDP 792
S+ SPCT Q AC ++ ++ CH LV ++ CL C
Sbjct: 2244 VSKPCP--SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG 2301
Query: 793 GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPE 848
LCP ++ Y C GA WR CP CP Y C +C C PE
Sbjct: 2302 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE 2361
Query: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM---KECNR-CIC 904
C +C GC C G + + CVP C C L RY P T C+ C C
Sbjct: 2362 GCE--SACREGCVCDAGFVLSGD-TCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLCRC 2417
Query: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
+E G +C C C P+G + GCV T
Sbjct: 2418 REGGEVSCEPSSCGPHETCR-----------------------PSGGSLGCVAVGSTT-- 2452
Query: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
C+ SG PHY T
Sbjct: 2453 -----------CQASGD--------------------------------------PHYTT 2463
Query: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 2464 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 2523
Query: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 2524 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 2583
Query: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEP-------GDL 1187
+ GLCG+++GD +D + G A +SW SP P P G +
Sbjct: 2584 YQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCI 2643
Query: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
P C + CG L P L CH V PQ + C++D C GG+
Sbjct: 2644 PSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 2701
Query: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE-----QHPE 1298
LCS I Y C G V WR++ C ++C YE C TC C Q P+
Sbjct: 2702 LCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD 2761
Query: 1299 PGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQ 1356
C EGC C G L +G AC+ C C G P +VL +C CTC
Sbjct: 2762 --------GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCH 2813
Query: 1357 EGQWHCGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEE 1409
G+ C+E +C G+ +CQ +G CV HG C Q+ C + +
Sbjct: 2814 VGKVVV------CQE--HSCKPGQ-VCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQG 2864
Query: 1410 GC 1411
C
Sbjct: 2865 VC 2866
Score = 350 bits (899), Expect = 2e-95
Identities = 350/1322 (26%), Positives = 490/1322 (37%), Gaps = 229/1322 (17%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH-LTP--------GDRCPQPG 243
ATC W HY +FDGR + F G C Y+LA + LTP P
Sbjct: 2872 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 2931
Query: 244 HCQRVTMGPEEVLI-----QAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
+ + VT+ I + G V V G L S +S+ +L G+
Sbjct: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991
Query: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
V D + +++ G GLCG + P +D + P G LA +G SWR PG +
Sbjct: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051
Query: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
C D + P ++ PG A GPF CHA V P + + C
Sbjct: 3052 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT-----GGPFTTCHAHVPPESFFKGC 3106
Query: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSD 477
+ C G G + +C ASYV AC + I WR CE CP Y
Sbjct: 3107 VLDVCMGG-------GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 3159
Query: 478 CVSLCPPSCEAVGQGEEES-CREECVSGCECPRGLFWNGTLCVPAAH-CPCYY------- 528
C CP SC + + C CV GC+C G + CVP + C C+
Sbjct: 3160 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 3219
Query: 529 ---------CRQ--RYVPGDTVRQLCNPCVCRDGR--------WHCAQALCPAECAVGGD 569
C Q R PG +C P C G H Q + AEC GD
Sbjct: 3220 GSEFWADGTCSQWCRCGPGGG-SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 3278
Query: 570 GHYLTFDGRSYSFWGGQGCRYSL----------VQDYVKGQLLILLEHGACDAGSCLHAI 619
HY+T DG + F G C Y L +++ + + EH A S ++
Sbjct: 3279 PHYVTLDGHRFDFQG--TCEYLLSAPCHGPPLGAENFT---VTVANEHRGSQAVSYTRSV 3333
Query: 620 SVSLEDTHIQL--RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
++ + + + L R + V+G V LP+ + L S A +++ L
Sbjct: 3334 TLQIYNHSLTLSARWPRKLQVDGVFVTLPF-QLDSLLHAHLSGADVVVTTTSGLSLAFDG 3392
Query: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGK---GRC 734
D + + +A + GLCG + Q+ DD G + +QV G G C
Sbjct: 3393 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 3444
Query: 735 PSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAVCGCDP 792
S+ SPCT Q AC ++ ++ CH LV ++ CL C
Sbjct: 3445 VSKPCP--SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG 3502
Query: 793 GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPE 848
LCP ++ Y C GA WR CP CP Y C +C C PE
Sbjct: 3503 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE 3562
Query: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM---KECNR-CIC 904
C +C GC C G + + CVP C C L RY P T C+ C C
Sbjct: 3563 GCE--SACREGCVCDAGFVLSGD-TCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLCRC 3618
Query: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
+E G +C C C P+G + GCV T
Sbjct: 3619 REGGEVSCEPSSCGPHETCR-----------------------PSGGSLGCVAVGSTT-- 3653
Query: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
C+ SG PHY T
Sbjct: 3654 -----------CQASGD--------------------------------------PHYTT 3664
Query: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 3665 FDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 3724
Query: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 3725 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 3784
Query: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEP-------GDL 1187
+ GLCG+++GD +D + G A +SW SP P P G +
Sbjct: 3785 YQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCI 3844
Query: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
P C + CG L P L CH V PQ + C++D C GG+
Sbjct: 3845 PSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 3902
Query: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE-----QHPE 1298
LCS I Y C G HV WR++ C ++C YE C TC C Q P+
Sbjct: 3903 LCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD 3962
Query: 1299 PGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQ 1356
C EGC C G L +G AC+ C C G P +VL +C CTC
Sbjct: 3963 --------GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCH 4014
Query: 1357 EGQWHCGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEE 1409
G+ C+E +C G+ +CQ +G CV HG C Q+ C + +
Sbjct: 4015 VGKVVV------CQE--HSCKPGQ-VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065
Query: 1410 GC 1411
C
Sbjct: 4066 VC 4067
Score = 300 bits (767), Expect = 3e-80
Identities = 270/901 (29%), Positives = 362/901 (40%), Gaps = 138/901 (15%)
Query: 546 CVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL 605
C G+ C A A C GD HY TFDGR Y G C Y++V+ + L
Sbjct: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMG--TCSYTMVELCSEDDTLPAF 511
Query: 606 ------EHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLVNGQDVGLPWIGAEG-LSVR 656
EH S + ++V + L + G VLV+ Q LP +EG L V
Sbjct: 512 SVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVY 571
Query: 657 RASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVE 716
++ ++ G V + +A ++L R QV GLCG + + DDFLTP G +
Sbjct: 572 QSGPRAVVELVFGLVVTYDWDCQLA-LSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
Query: 717 TSIAAFASKFQV-AGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILH--SSVFQECHRL 773
FAS +++ G C CT +H + C +L F CH
Sbjct: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
Query: 774 VDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQE 832
+D PF +C+ +C LC LSAYA+ C + G S WR+ CP+ CP
Sbjct: 691 LDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSR 750
Query: 833 YRECAPACGQHC---GKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
Y C PAC C P +C CV GC C G + G CVP S C C +
Sbjct: 751 YELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFV-ASGGACVPASSCGCTFQGLQL 808
Query: 890 APGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPA 949
APG + +CQ R CT Q C SCPA
Sbjct: 809 APGQEVWAD---ELCQRR----CTCNGATHQVTC------------------RDKQSCPA 843
Query: 950 GSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
G ERC ++Q C
Sbjct: 844 G---------------ERC-------------------SVQNGLLGCY----------PD 859
Query: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLV-----REASGLFTVSAQNLPCGASGLTC 1064
R G CQ SG PHYV+FDG F + G C YLLV A F V +N G+ ++
Sbjct: 860 RFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSY 919
Query: 1065 TKALAVRLEGTVVHMLR---GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLT 1121
T+A+ V G V + R G+ + + + P + G + + R G ++ T GLT
Sbjct: 920 TRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ-VQVFRQGRDAVVRTDFGLT 978
Query: 1122 LLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--LSP 1179
+ +D RV ++ + + GLCG+F+GD ++DL R G A +SW+ P
Sbjct: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
Query: 1180 LC--PEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACG 1235
C EPGD P ++ + ++ CG L P F CH+++ PQ C+YD C
Sbjct: 1039 GCGATEPGDCPKLDSLVAQQL-QSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
Query: 1236 CDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE 1294
G LC A+ATYA C G V WRS+ELC L C YEAC CP +C +
Sbjct: 1098 LP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
Query: 1295 QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCT 1354
P PG C C EGC C EG L G +CL ASC C PPG
Sbjct: 1156 L-PVPG-GCG-SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFY------- 1205
Query: 1355 CQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C+ L C EG + E+ C PH + C GC A
Sbjct: 1206 ----------PGPGCDSLC-HCQEGGLVSCESSSCGPH-------EACQPSGGSLGCVAV 1247
Query: 1415 G 1415
G
Sbjct: 1248 G 1248
Score = 244 bits (624), Expect = 1e-63
Identities = 298/1223 (24%), Positives = 425/1223 (34%), Gaps = 247/1223 (20%)
Query: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
D +++G + P + + P P CP P T PA P G C
Sbjct: 4341 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 4393
Query: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 4394 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 4437
Query: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 4438 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 4494
Query: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 4495 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 4554
Query: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 4555 VDGVFVALPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 4606
Query: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV----------- 365
GLCG YN P DD GG A W++ G++ GC + V
Sbjct: 4607 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGECVSKPCPSPCTPE 4657
Query: 366 --EVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
E G D G+I A +GP CH V PA+Y + CL C
Sbjct: 4658 QQESFGGPDACGVISA------------------TDGPLAPCHGLVPPAQYFQGCLLDAC 4699
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYSDCVSLC 482
+G +C A+YV AC + WR+P FC CP Y C C
Sbjct: 4700 Q-------VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 4752
Query: 483 PPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPG 536
P SC ++ E C C GC C G +G CVP C C Y + + PG
Sbjct: 4753 PVSCPSL--SAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 4810
Query: 537 DTVRQLC-------------------NPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDG 577
+ C C DG C C C G HY+T DG
Sbjct: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDG 4869
Query: 578 RSYSFWGGQGCRYSLVQ----DYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDS 633
R Y G C Y L Q I+LE A AG L + V++ + L
Sbjct: 4870 RVYDLHG--SCSYVLAQVCHPKPGDEDFSIVLEKNA--AGD-LQRLLVTVAGQVVSLAQG 4924
Query: 634 GAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQV 693
V V+G+ V LP + + V +L G ++L+ D +++ ++
Sbjct: 4925 QQVTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFD-GDAHLLMSIPSPFRGRL 4982
Query: 694 QGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL--LSPCTTHSQR 751
GLCG F N DDF+ P G +S+ F + ++ G + E C
Sbjct: 4983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETA 5042
Query: 752 HAFAEAACAILHS--SVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCA 809
+ AC L + F C ++ ++ +C+ +C LC L+AY C
Sbjct: 5043 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 5102
Query: 810 QEG-ASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPED-CGELGSCVAGCNCPLGLL 867
G A PWR + CP+ CP Y C C C G C GC C L
Sbjct: 5103 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFL 5162
Query: 868 WDPEGQCVPPSLCPCQLGARRYAPGSATM--KECN-RCICQERGLWNCTARHCPSQAFC- 923
+G C+P C C RY P ++++ +C+ RC C C A CP C
Sbjct: 5163 LS-QGVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE 5220
Query: 924 ----PRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHS 979
R G C+L S AN + G+ G PG L RC P L +++
Sbjct: 5221 VKAEARNCWATRGLCVL---SVGANLTTFDGAR-GATTSPGVYELSSRC--PGL---QNT 5271
Query: 980 GQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYL 1039
WY A +Q +C G+ +A G H DG+ P
Sbjct: 5272 IPWYRVVAEVQ------ICH------------GKTEAVGQVHIFFQDGMVTLTP------ 5307
Query: 1040 LVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYT 1099
+ V VNG+ V P
Sbjct: 5308 ------------------------------------------NKGVWVNGLRVDLPAEKL 5325
Query: 1100 GPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRS 1159
R LL+ G+ + +V V +S G++ G CG+FDGD +ND
Sbjct: 5326 ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHD 5385
Query: 1160 RQGVLEPTAELAAHSWRLSPLCP 1182
Q + A WR P
Sbjct: 5386 SQ------EKPAMEKWRAQDFSP 5402
Score = 196 bits (497), Expect = 7e-49
Identities = 164/561 (29%), Positives = 228/561 (40%), Gaps = 55/561 (9%)
Query: 836 CAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARR--YAPGS 893
C P + G P+ CG + S G P L P L CQ+ P
Sbjct: 4654 CTPEQQESFGGPDACGVI-SATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAV 4712
Query: 894 ATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY--APGACLLTCDSPSANHSCPAGS 951
AT + + G W CP Q CP Y +C ++C S SA C +
Sbjct: 4713 ATYVAACQAAGAQLGEWR-RPDFCPLQ--CPAHSHYELCGDSCPVSCPSLSAPEGCESAC 4769
Query: 952 TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWY------LPNATIQEDCN-------VC-- 996
+GCVC G VL + CVP C C H G++Y P + C C
Sbjct: 4770 REGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 4829
Query: 997 --------VCR----GRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREA 1044
CR + H TG GRC A+G HY+T DG + G+C Y+L +
Sbjct: 4830 GAACGPHEECRLEDGVQACHATG---CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVC 4886
Query: 1045 SGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLS 1104
++ + + L V + G VV + +G+ VTV+G +V P V G +
Sbjct: 4887 HPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALP-VAVG-RVR 4944
Query: 1105 LRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
+ G ++L T GL LL+DG +L+ + FRGR+ GLCG+F+G+ S+D G
Sbjct: 4945 VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA 5004
Query: 1165 EPTAELAAHSWRL---SPLCPEP-GDLPHPCTMNTHRAGW-ARARCGALLQPL--FTLCH 1217
+ E +WR S C E G P + A + + CG L P F C
Sbjct: 5005 ASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQ 5064
Query: 1218 AEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCE 1276
A + P +++ C+YD C GD LC ++A Y C G V+ WR+ C L C
Sbjct: 5065 AVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCP 5122
Query: 1277 GGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWG 1336
Y C TC +C G C EGC C + LL G C+ C C
Sbjct: 5123 AHSHYSICTRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTHN 5179
Query: 1337 RNSFP-PGSVLQKDCG-NCTC 1355
P S+L DC C+C
Sbjct: 5180 GRYLPVNSSLLTSDCSERCSC 5200
Score = 85.1 bits (209), Expect = 2e-15
Identities = 92/319 (28%), Positives = 114/319 (35%), Gaps = 49/319 (15%)
Query: 4494 PGDRLQLGCKECECRRGELHCTSQGCQGLLPLS------EWSEWSPCGPCLPPSALAPAS 4547
PG+ QL C C G+ Q G + W E P PCLPP P S
Sbjct: 2580 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 2639
Query: 4548 RTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCP 4607
+ S P L + + C G T PLS
Sbjct: 2640 EGCIP----------SEECPPELEKKYQKEEFC----------GLLSSPTGPLSSCHKLV 2679
Query: 4608 DPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPEC 4667
DP C + L + CS + + GG EPW E+ CP
Sbjct: 2680 DPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQAAGGQVEPWRNETFCPMECP-- 2734
Query: 4668 EAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGL 4727
Q++ + L CA+ C C+ L +QC G C GC+C G L CVPI C C
Sbjct: 2735 --QNSHYEL-CADTCSLGCSALSAPLQCPDG-CAEGCQCDSGFLYNGQACVPIQQCGCYH 2790
Query: 4728 PSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQEC---PVLGPWSAWSSC--SAPC 4779
A P Q V +D C Q CTC V + +VC C V P SC PC
Sbjct: 2791 NGA----YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPC 2846
Query: 4780 GGGTMERHRTC--EGGPGV 4796
G T TC +GG GV
Sbjct: 2847 HGVTCRPQETCKEQGGQGV 2865
Score = 84.3 bits (207), Expect = 3e-15
Identities = 92/319 (28%), Positives = 116/319 (36%), Gaps = 49/319 (15%)
Query: 4494 PGDRLQLGCKECECRRGELHCTSQGCQGLLPLS------EWSEWSPCGPCLPPSALAPAS 4547
PG+ QL C C G+ Q G + W E P PCLPP P S
Sbjct: 3781 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 3840
Query: 4548 RTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCP 4607
+ P+ P P L + + C G T PLS
Sbjct: 3841 AGCI-------PSDKCP---PELEKKYQKEEFC----------GLLSSPTGPLSSCHKLV 3880
Query: 4608 DPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPEC 4667
DP C + L + CS + + GG EPW E+ CP
Sbjct: 3881 DPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQAAGGHVEPWRNETFCPMECP-- 3935
Query: 4668 EAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGL 4727
Q++ + L CA+ C C+ L +QC G C GC+C G L CVPI C C
Sbjct: 3936 --QNSHYEL-CADTCSLGCSALSAPLQCPDG-CAEGCQCDSGFLYNGQACVPIQQCGC-- 3989
Query: 4728 PSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQEC---PVLGPWSAWSSC--SAPC 4779
+ P Q V +D C Q CTC V + +VC C V P SC PC
Sbjct: 3990 --YHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPC 4047
Query: 4780 GGGTMERHRTC--EGGPGV 4796
G T TC +GG GV
Sbjct: 4048 HGVTCRPQETCKEQGGQGV 4066
Score = 83.2 bits (204), Expect = 6e-15
Identities = 79/281 (28%), Positives = 98/281 (34%), Gaps = 43/281 (15%)
Query: 4526 SEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPAT 4585
+ W E P PCLPP+ P S + H P L + + C
Sbjct: 1417 NSWEEVVPDSPCLPPTPCPPGSEDCIPSH----------KCPPELEKKYQKEEFC----- 1461
Query: 4586 GRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
G T PLS DP C + L + CS + +
Sbjct: 1462 -----GLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQ 1513
Query: 4646 CGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
GG EPW E+ CP + CA+ C C+ L QC G C GC+
Sbjct: 1514 AAGGHVEPWRTETFCPMECPPNSHYEL-----CADTCSLGCSALSAPPQCQDG-CAEGCQ 1567
Query: 4706 CPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQE 4762
C G L CVPI C C + P Q V +D C Q CTC + +VC
Sbjct: 1568 CDSGFLYNGQACVPIQQCGC----YHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHS 1623
Query: 4763 C---PVLGPWSAWSSC--SAPCGGGTMERHRTC--EGGPGV 4796
C V P SC PC G T TC +GG GV
Sbjct: 1624 CKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGV 1664
Score = 79.3 bits (194), Expect = 9e-14
Identities = 99/366 (27%), Positives = 131/366 (35%), Gaps = 100/366 (27%)
Query: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
W+ V PC P CPPG +D C+P C CGL S+ ++
Sbjct: 1419 WEEV-VPDSPCLPPTPCPPGS--ED--CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
Query: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
+L Q DC C+ N S++C + V S+C A GG +E RT
Sbjct: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGHVEPWRT 1524
Query: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
+T CP ECPP CA +C C L C Q+
Sbjct: 1525 -------------ETF---------CPMECPPNSHYELCADTCSLGCSALSAPPQC-QDG 1561
Query: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
C GC C G L + CVP C C + + + P TVL NC +C
Sbjct: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE------------PEQTVLIDNCRQQC 1609
Query: 4908 VCHGG-AFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
CH G C C+ PG+ Q G + C T+ C G C
Sbjct: 1610 TCHAGKGMVCQEHSCK--PGQVCQ--PSGGILSC----------VTKDPC-----HGVTC 1650
Query: 4967 QPGHF---RSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQ 5017
+P + G C+P CW G PH ++Q C L +G P V TQ
Sbjct: 1651 RPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQ 1710
Query: 5018 HCSPLT 5023
+P T
Sbjct: 1711 GLTPFT 1716
Score = 75.1 bits (183), Expect = 2e-12
Identities = 129/543 (23%), Positives = 175/543 (32%), Gaps = 127/543 (23%)
Query: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
+P C CPA C CP C+ C + C +GC C G + G CVP
Sbjct: 737 SPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFVASGGACVP 795
Query: 4114 IGHCDCTDAQGHSWAPGSQ-----------------HQDACNN---------CSCQAGQL 4147
C CT QG APG + HQ C + CS Q G L
Sbjct: 796 ASSCGCT-FQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854
Query: 4148 SC------TAQPCPPPTHCAWS--HWSAWSPCSH----SCGPRGQQSRFR--------SS 4187
C T Q P + ++ + C++ SCG FR S
Sbjct: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS 914
Query: 4188 TSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICED 4247
+ S+ R E + + P L + L G+ Q + V+ D
Sbjct: 915 QTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 974
Query: 4248 TECAVPEAWT------LWSSWSDCPVS-CGG--GNQVRTRACRAAAPHHRSPPCLGPDTQ 4298
V W + SS+++ CG G+ A R ++ L
Sbjct: 975 FGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG---QAANALAFGNS 1031
Query: 4299 TRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCP---CLMAKADPTCNSTFLHLDTQ 4355
+++ PG CG A+ G CP L+A+ + N + D +
Sbjct: 1032 WQEETRPG----------------CG---ATEPGDCPKLDSLVAQQLQSKNECGILADPK 1072
Query: 4356 G----CYSGPCPE----ECVWSSWSSWTRCSCRVLVQQRYRHQGPASRG-ARAGAPCTRL 4406
G C+S P+ +CV+ RC +L Q GP A A C
Sbjct: 1073 GPFRECHSKLDPQGAVRDCVYD------RC---LLPGQ----SGPLCDALATYAAACQAA 1119
Query: 4407 DGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLP-------PCQPGC 4459
P SC P + AC C LS C DLP C GC
Sbjct: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYGCP------LS---CGDLPVPGGCGSECHEGC 1170
Query: 4460 YCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAPGDRLQLGCKE-CECRRGEL-HCTS 4516
C +G C+P C C H G T PG GC C C+ G L C S
Sbjct: 1171 VCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES 1226
Query: 4517 QGC 4519
C
Sbjct: 1227 SSC 1229
Score = 74.7 bits (182), Expect = 2e-12
Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C+ G P SC +L P G CH GC C G L C+P C C
Sbjct: 1133 PLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCV 1192
Query: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
H+G +PPG T C++ C C G + +C S C P C S G
Sbjct: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG----------PHEACQPSGGSL 1242
Query: 3203 RC 3204
C
Sbjct: 1243 GC 1244
Score = 73.2 bits (178), Expect = 6e-12
Identities = 94/363 (25%), Positives = 123/363 (33%), Gaps = 94/363 (25%)
Query: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
W+ V PC P CPPG +G C+P C CGL S+ ++
Sbjct: 2620 WEEV-VPDSPCLPPPTCPPGS---EG-CIPSEECPPELEKKYQKEEFCGLLSSPTGPLSS 2674
Query: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
+L Q DC C+ N S++C + V S+C A GG +E R
Sbjct: 2675 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGQVEPWR- 2724
Query: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
N CP ECP CA +C C L C +
Sbjct: 2725 ---------------------NETFCPMECPQNSHYELCADTCSLGCSALSAPLQC-PDG 2762
Query: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
C GC C G L + CVP C C + A P TVL NC +C
Sbjct: 2763 CAEGCQCDSGFLYNGQACVPIQQCGCYHNG------------AYYEPEQTVLIDNCRQQC 2810
Query: 4908 VCH-GGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
CH G C C+ PG+ Q + G L + + Q C
Sbjct: 2811 TCHVGKVVVCQEHSCK--PGQVCQP-SGGILSCVNKDPCHGVTCRPQETCKE-------- 2859
Query: 4967 QPGHFRSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQHCS 5020
+ G C+P CW G PH ++Q C L +G P V TQ +
Sbjct: 2860 -----QGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
Query: 5021 PLT 5023
P T
Sbjct: 2915 PFT 2917
Score = 73.2 bits (178), Expect = 6e-12
Identities = 95/366 (25%), Positives = 125/366 (34%), Gaps = 100/366 (27%)
Query: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
W+ V PC P CPPG C+P C CGL S+ ++
Sbjct: 3821 WEEV-VPDSPCLPPPTCPPGS----AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSS 3875
Query: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
+L Q DC C+ N S++C + V S+C A GG +E R
Sbjct: 3876 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGHVEPWR- 3925
Query: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
N CP ECP CA +C C L C +
Sbjct: 3926 ---------------------NETFCPMECPQNSHYELCADTCSLGCSALSAPLQC-PDG 3963
Query: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
C GC C G L + CVP C C + + + P TVL NC +C
Sbjct: 3964 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE------------PEQTVLIDNCRQQC 4011
Query: 4908 VCH-GGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
CH G C C+ PG+ Q G + C T+ C G C
Sbjct: 4012 TCHVGKVVVCQEHSCK--PGQVCQ--PSGGILSC----------VTKDPC-----HGVTC 4052
Query: 4967 QPGHF---RSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQ 5017
+P + G C+P CW G PH ++Q C L +G P V TQ
Sbjct: 4053 RPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQ 4112
Query: 5018 HCSPLT 5023
+P T
Sbjct: 4113 GLTPFT 4118
Score = 70.5 bits (171), Expect = 4e-11
Identities = 69/277 (24%), Positives = 91/277 (32%), Gaps = 91/277 (32%)
Query: 2922 CAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYA-------SGAMARLDSCNNCTCVSGK 2974
C P TCPPG +A C+P +CP +L + S L SC+ G
Sbjct: 3830 CLPPPTCPPG----SAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 3885
Query: 2975 MACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFC 3034
+ + C ++ LC N+ I C
Sbjct: 3886 L----KDC----------IFDLCLGGGNLSI---------------------------LC 3904
Query: 3035 S-----LRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGM 3089
S + C GG PW RN T P
Sbjct: 3905 SNIHAYVSACQAAGGHVEPW-----------RNETF--------------------CPME 3933
Query: 3090 CPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
CP++ + CA + C+ LSAP C GC C SG L CVP Q C C H G
Sbjct: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 3993
Query: 3149 HLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Y P TV + C + C+C G + C C G+
Sbjct: 3994 VYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030
Score = 70.1 bits (170), Expect = 5e-11
Identities = 68/277 (24%), Positives = 91/277 (32%), Gaps = 91/277 (32%)
Query: 2922 CAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYA-------SGAMARLDSCNNCTCVSGK 2974
C P TCPPG + C+P +CP +L + S L SC+ G
Sbjct: 2629 CLPPPTCPPG----SEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 2684
Query: 2975 MACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFC 3034
+ + C ++ LC N+ I C
Sbjct: 2685 L----KDC----------IFDLCLGGGNLSI---------------------------LC 2703
Query: 3035 S-----LRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGM 3089
S + C GG+ PW RN T P
Sbjct: 2704 SNIHAYVSACQAAGGQVEPW-----------RNETF--------------------CPME 2732
Query: 3090 CPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
CP++ + CA + C+ LSAP C GC C SG L CVP Q C C H G
Sbjct: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 2792
Query: 3149 HLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Y P TV + C + C+C G + C C G+
Sbjct: 2793 AYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829
Score = 69.7 bits (169), Expect = 7e-11
Identities = 41/123 (33%), Positives = 48/123 (39%), Gaps = 13/123 (10%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 4736 PLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 4795
Query: 3146 HEGHLYPPGSTVV--RPCE-NCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
H+G YP G CE C C G C EG + P +C G
Sbjct: 4796 HDGRYYPLGEVFYPGPECERRCECGPG-----GHVTCQEG----AACGPHEECRLEDGVQ 4846
Query: 3203 RCH 3205
CH
Sbjct: 4847 ACH 4849
Score = 68.6 bits (166), Expect = 2e-10
Identities = 66/243 (27%), Positives = 86/243 (35%), Gaps = 41/243 (16%)
Query: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
G AGN SW P PC C G + + +++ P P + YQ+
Sbjct: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCP-------PELEKKYQKE 1458
Query: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
FC L + P P S C + C GG +L S CS+ +
Sbjct: 1459 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 1510
Query: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
AG H C CP CA+ C CS L CQD C +GC+
Sbjct: 1511 ACQAAGG-HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQ 1567
Query: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
C G L CVPI C C + + D C C+C AG+ + C C P
Sbjct: 1568 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPG 1627
Query: 4158 THC 4160
C
Sbjct: 1628 QVC 1630
Score = 68.2 bits (165), Expect = 2e-10
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 2334 PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 2393
Query: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGE 3183
H+ YP G T C++ C C G +C C E
Sbjct: 2394 HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHE 2434
Score = 68.2 bits (165), Expect = 2e-10
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 3535 PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 3594
Query: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGE 3183
H+ YP G T C++ C C G +C C E
Sbjct: 3595 HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHE 3635
Score = 67.0 bits (162), Expect = 5e-10
Identities = 35/99 (35%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C + SCA LS G C GC C LL VC+P QDC C
Sbjct: 5118 PLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCT 5177
Query: 3146 HEGHLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEG 3182
H G P S+++ E CSC S C + C G
Sbjct: 5178 HNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
Score = 66.2 bits (160), Expect = 8e-10
Identities = 64/243 (26%), Positives = 86/243 (35%), Gaps = 41/243 (16%)
Query: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
G AGN SW P PC +C G + + + P P + YQ+
Sbjct: 2607 GSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECP-------PELEKKYQKE 2659
Query: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
FC L + P P S C + C GG +L S CS+ +
Sbjct: 2660 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 2711
Query: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
AG + + N C CP CA+ C CS L + C D C +GC+
Sbjct: 2712 ACQAAGGQVEPWR-NETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQ 2768
Query: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
C G L CVPI C C + + D C C+C G+ + C C P
Sbjct: 2769 CDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 2828
Query: 4158 THC 4160
C
Sbjct: 2829 QVC 2831
Score = 65.9 bits (159), Expect = 1e-09
Identities = 65/243 (26%), Positives = 85/243 (34%), Gaps = 41/243 (16%)
Query: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
G AGN SW P PC +C G + + + P P + YQ+
Sbjct: 3808 GSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCP-------PELEKKYQKE 3860
Query: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
FC L + P P S C + C GG +L S CS+ +
Sbjct: 3861 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 3912
Query: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
AG H N C CP CA+ C CS L + C D C +GC+
Sbjct: 3913 ACQAAGG-HVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQ 3969
Query: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
C G L CVPI C C + + D C C+C G+ + C C P
Sbjct: 3970 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 4029
Query: 4158 THC 4160
C
Sbjct: 4030 QVC 4032
Score = 65.1 bits (157), Expect = 2e-09
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Query: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + + CA + C+ LSAP C GC C SG L CVP Q C C
Sbjct: 1529 PMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCY 1588
Query: 3146 HEGHLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
H G Y P TV + C + C+C +G C C G+
Sbjct: 1589 HNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQ 1628
Score = 63.9 bits (154), Expect = 4e-09
Identities = 64/211 (30%), Positives = 76/211 (36%), Gaps = 54/211 (25%)
Query: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP----PPKNG-GAPCPGASQERAP--- 2603
G+W W+ W C SC + R P P +G G P P
Sbjct: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
Query: 2604 ---CGLQPCSGGTD----CELGRVYVSADLCQKGLV------------------------ 2632
C L C GG D C+ YV+A CQ V
Sbjct: 4304 FKGCVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEVC 4361
Query: 2633 -PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWPG 2687
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C G
Sbjct: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
Query: 2688 VSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
F G CSQ C C G L+C P C L
Sbjct: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGL 4452
Score = 63.5 bits (153), Expect = 5e-09
Identities = 65/212 (30%), Positives = 77/212 (36%), Gaps = 56/212 (26%)
Query: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP------PPKNGG------APCPGASQ 2599
G+W W+ W C SC + R P P GG A P S
Sbjct: 3043 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 3102
Query: 2600 ERAPCGLQPCSGGTD----CELGRVYVSADLCQKGLV----------------------- 2632
+ C L C GG D C+ YV+A CQ V
Sbjct: 3103 FKG-CVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEV 3159
Query: 2633 --PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWP 2686
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C
Sbjct: 3160 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 3219
Query: 2687 GVSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
G F G CSQ C C G L+C P C L
Sbjct: 3220 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 3251
Score = 62.8 bits (151), Expect = 9e-09
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 1846 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLAPGTGGPFTTCHAHVPP 1898
Query: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
C GG R C +LA C D Q C CPEN +
Sbjct: 1899 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 1956
Query: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 1957 --EVC---GSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 2011
Query: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 2012 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 2058
Score = 62.0 bits (149), Expect = 1e-08
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 3047 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLAPGTGGPFTTCHAHVPP 3099
Query: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
C GG R C +LA C D Q C CPEN +
Sbjct: 3100 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 3157
Query: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 3158 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 3212
Query: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 3213 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 3259
Score = 62.0 bits (149), Expect = 1e-08
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 4248 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLSSGTGGPFTTCHAHVPP 4300
Query: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
C GG R C +LA C D Q C CPEN +
Sbjct: 4301 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 4358
Query: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 4359 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 4413
Query: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 4414 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 4460
Score = 61.2 bits (147), Expect = 3e-08
Identities = 45/123 (36%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
C CP SC C PC GC C PG + G CVP SSC C +LA
Sbjct: 754 CGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGL----QLA 809
Query: 4738 PAQAVQLD--CQ-NCTC--VNESLVC-PHQECPVLGPWSAWSSCSAPCG--GGTMERHRT 4789
P Q V D CQ CTC + C Q CP A CS G G +R T
Sbjct: 810 PGQEVWADELCQRRCTCNGATHQVTCRDKQSCP------AGERCSVQNGLLGCYPDRFGT 863
Query: 4790 CEG 4792
C+G
Sbjct: 864 CQG 866
Score = 60.5 bits (145), Expect = 4e-08
Identities = 64/212 (30%), Positives = 76/212 (35%), Gaps = 56/212 (26%)
Query: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP------PPKNGG------APCPGASQ 2599
G+W W+ W C SC + R P P GG A P S
Sbjct: 1842 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 1901
Query: 2600 ERAPCGLQPCSGGTD----CELGRVYVSADLCQKGLV----------------------- 2632
+ C L C GG D C+ YV+A CQ V
Sbjct: 1902 FKG-CVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEV 1958
Query: 2633 --PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWP 2686
PCP SC P + C G CVEGC+C G +L RC+PL+ C C
Sbjct: 1959 CGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 2018
Query: 2687 GVSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
G F G CSQ C C G L+C P C L
Sbjct: 2019 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2050
Score = 60.1 bits (144), Expect = 6e-08
Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 9/129 (6%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
CS++ + C Q + C +CP+N + E C C C
Sbjct: 2703 CSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHY---ELC---ADTCSLGCSALSAP 2756
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC-NNCTCVSGK 2974
++C CA GC C G + +C+P QC C +G Y +D+C CTC GK
Sbjct: 2757 LQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGK 2816
Query: 2975 -MACTSERC 2982
+ C C
Sbjct: 2817 VVVCQEHSC 2825
Score = 59.3 bits (142), Expect = 1e-07
Identities = 44/141 (31%), Positives = 51/141 (36%), Gaps = 30/141 (21%)
Query: 2590 GGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCS 2649
G P S+E P P S C G CP SC D C
Sbjct: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYG----------------CPLSCGDLPVPGGCG 1163
Query: 2650 GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG-NC-SQCVCEKGELL- 2706
C EGC C G L CLPL+ C C+ PG +F G C S C C++G L+
Sbjct: 1164 SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVS 1223
Query: 2707 -----------CQPGGCPLPC 2716
CQP G L C
Sbjct: 1224 CESSSCGPHEACQPSGGSLGC 1244
Score = 59.3 bits (142), Expect = 1e-07
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
CS++ + C T+ C +CP N + E C C C
Sbjct: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHY---ELC---ADTCSLGCSALSAP 1555
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC-NNCTCVSGK 2974
+C CA GC C G + +C+P QC C +G Y +D+C CTC +GK
Sbjct: 1556 PQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 1615
Query: 2975 -MACTSERC 2982
M C C
Sbjct: 1616 GMVCQEHSC 1624
Score = 59.3 bits (142), Expect = 1e-07
Identities = 71/248 (28%), Positives = 92/248 (37%), Gaps = 45/248 (18%)
Query: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 2230 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2286
Query: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
G + +G PG VA CQA + R+ CP +CP C
Sbjct: 2287 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC 2346
Query: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 2347 GDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPL---- 2401
Query: 4888 EEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEM 4947
Q PG C RC GG SC C P ET + + G LG C+ +
Sbjct: 2402 ---GQTFYPGPGCDSLC-RC-REGGEVSCEPSSC--GPHETCRP-SGGSLG-----CVAV 2448
Query: 4948 NATKTQSN 4955
+T Q++
Sbjct: 2449 GSTTCQAS 2456
Score = 59.3 bits (142), Expect = 1e-07
Identities = 71/248 (28%), Positives = 92/248 (37%), Gaps = 45/248 (18%)
Query: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 3431 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 3487
Query: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
G + +G PG VA CQA + R+ CP +CP C
Sbjct: 3488 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC 3547
Query: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 3548 GDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPL---- 3602
Query: 4888 EEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEM 4947
Q PG C RC GG SC C P ET + + G LG C+ +
Sbjct: 3603 ---GQTFYPGPGCDSLC-RC-REGGEVSCEPSSC--GPHETCRP-SGGSLG-----CVAV 3649
Query: 4948 NATKTQSN 4955
+T Q++
Sbjct: 3650 GSTTCQAS 3657
Score = 58.5 bits (140), Expect = 2e-07
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 13/110 (11%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 2333 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 2390
Query: 4118 DCTDAQ-----GHSWAPGSQHQDACNN-CSC-QAGQLSCTAQPCPPPTHC 4160
C G ++ PG C++ C C + G++SC C P C
Sbjct: 2391 GCLHDDRYYPLGQTFYPG----PGCDSLCRCREGGEVSCEPSSCGPHETC 2436
Score = 58.5 bits (140), Expect = 2e-07
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 13/110 (11%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 3534 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 3591
Query: 4118 DCTDAQ-----GHSWAPGSQHQDACNN-CSC-QAGQLSCTAQPCPPPTHC 4160
C G ++ PG C++ C C + G++SC C P C
Sbjct: 3592 GCLHDDRYYPLGQTFYPG----PGCDSLCRCREGGEVSCEPSSCGPHETC 3637
Score = 58.5 bits (140), Expect = 2e-07
Identities = 52/198 (26%), Positives = 71/198 (35%), Gaps = 26/198 (13%)
Query: 2804 CPSPGDSSC-PGDAT---------QEEPC---SPPVCPVPSIWGL---WAPWSTCSAPCD 2847
CP PG + C P D +EE C S P P+ S L P C
Sbjct: 3836 CP-PGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 3894
Query: 2848 GGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCP 2906
G CS++ + C + C +CP+N + E C C
Sbjct: 3895 LGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHY---ELC---ADTCS 3948
Query: 2907 RLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC- 2965
C ++C CA GC C G + +C+P QC C +G Y +D+C
Sbjct: 3949 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCR 4008
Query: 2966 NNCTCVSGK-MACTSERC 2982
CTC GK + C C
Sbjct: 4009 QQCTCHVGKVVVCQEHSC 4026
Score = 58.2 bits (139), Expect = 2e-07
Identities = 73/259 (28%), Positives = 89/259 (34%), Gaps = 63/259 (24%)
Query: 3600 QSRSAGSRFSSW-ESLEPGEVVTGPCDNCTCVAGIL--QCQEVPDC---PDPGVWSSWGP 3653
Q+ +A + +SW E PG T P D C + ++ Q Q +C DP GP
Sbjct: 1021 QAANALAFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPK-----GP 1074
Query: 3654 WEDCSVSCGGGEQLRS---RRCARPPCPGPARQSRTCSTQVCREAG-------------- 3696
+ +C +R RC P GP + C+ AG
Sbjct: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
Query: 3697 -CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQECPC 3753
CP Y C GCP SC + GC SE C EGC C EG +C + C C
Sbjct: 1135 SCPPHSHYEACS--YGCPLSCGDLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGC 1191
Query: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKL-SCSLDDCFEADG 3812
V T PGQ PG DS C C G L SC C
Sbjct: 1192 VHQ--------GTYHPPGQTFYPGPGCDS---------LCHCQEGGLVSCESSSC----- 1229
Query: 3813 GFGPWSPWGPCSRSCGGLG 3831
P C S G LG
Sbjct: 1230 -----GPHEACQPSGGSLG 1243
Score = 57.8 bits (138), Expect = 3e-07
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG- 2693
CP SC A C C EGC C G +L C+P+ +C CL + G +F G
Sbjct: 2350 CPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGP 2409
Query: 2694 NC-SQCVC-EKGELLCQPGGC 2712
C S C C E GE+ C+P C
Sbjct: 2410 GCDSLCRCREGGEVSCEPSSC 2430
Score = 57.8 bits (138), Expect = 3e-07
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG- 2693
CP SC A C C EGC C G +L C+P+ +C CL + G +F G
Sbjct: 3551 CPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGP 3610
Query: 2694 NC-SQCVC-EKGELLCQPGGC 2712
C S C C E GE+ C+P C
Sbjct: 3611 GCDSLCRCREGGEVSCEPSSC 3631
Score = 57.4 bits (137), Expect = 4e-07
Identities = 70/262 (26%), Positives = 93/262 (35%), Gaps = 43/262 (16%)
Query: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 1810 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 1866
Query: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWC--DRSCGGGQS 4025
RL Y PG G P + C+ P S + C D GGG
Sbjct: 1867 DRLEQYEGPGFCGPLAPGTGGPFTT---CHAHVPPE-------SFFKGCVLDVCMGGGD- 1915
Query: 4026 LRSRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC--- 4079
R C + S AG E +A+ + CE CP C + CP C
Sbjct: 1916 -RDILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGSPCPASCPSP 1970
Query: 4080 SDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQ 4132
+ L VC+ C +GC+C G + CVP+ + C C +A WA G+
Sbjct: 1971 APLTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTC 2028
Query: 4133 HQDACNNCSCQAGQLSCTAQPC 4154
Q C G L CT C
Sbjct: 2029 SQWC--RCGPGGGSLVCTPASC 2048
Score = 57.0 bits (136), Expect = 5e-07
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 2604 CGLQPCSGGTD----CELGRVYVSADLCQKGLVPP----------CPPS----------- 2638
C C GG + C YVSA G V P CPP+
Sbjct: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
Query: 2639 --CLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNC- 2695
C A C C EGC+C G L + C+P+ +C C P + L+ NC
Sbjct: 1547 LGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
Query: 2696 SQCVCEKGE-LLCQPGGC 2712
QC C G+ ++CQ C
Sbjct: 1607 QQCTCHAGKGMVCQEHSC 1624
Score = 56.2 bits (134), Expect = 8e-07
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CP C+ CP C DL C + C +GC C +G C+P+ C
Sbjct: 1132 CPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSE--CHEGCVCDEGFALSGESCLPLASC 1189
Query: 4118 DCTDAQGHSWAPGSQHQ--DACNN-CSCQAGQL-SCTAQPCPPPTHC 4160
C QG PG C++ C CQ G L SC + C P C
Sbjct: 1190 GCVH-QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEAC 1235
Score = 56.2 bits (134), Expect = 8e-07
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
C GH P C P + C C+ C+ + CQD C GC C
Sbjct: 1512 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD--GCAEGCQCD 1569
Query: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL-GCK-ECECRRGE-LHCTSQGC 4519
G L C+P ++C C+H G+ P + + C+ +C C G+ + C C
Sbjct: 1570 SGFLYNGQACVPIQQCGCYHN-----GVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC 1624
Query: 4520 Q 4520
+
Sbjct: 1625 K 1625
Score = 56.2 bits (134), Expect = 8e-07
Identities = 70/262 (26%), Positives = 92/262 (35%), Gaps = 43/262 (16%)
Query: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 3011 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 3067
Query: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWC--DRSCGGGQS 4025
RL Y PG G P + C+ P S + C D GGG
Sbjct: 3068 DRLEQYEGPGFCGPLAPGTGGPFTT---CHAHVPPE-------SFFKGCVLDVCMGGGD- 3116
Query: 4026 LRSRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC--- 4079
R C + S AG E +A+ + CE CP C CP C
Sbjct: 3117 -RDILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSP 3171
Query: 4080 SDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQ 4132
+ L VC+ C +GC+C G + CVP+ + C C +A WA G+
Sbjct: 3172 APLTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTC 3229
Query: 4133 HQDACNNCSCQAGQLSCTAQPC 4154
Q C G L CT C
Sbjct: 3230 SQWC--RCGPGGGSLVCTPASC 3249
Score = 56.2 bits (134), Expect = 8e-07
Identities = 63/242 (26%), Positives = 80/242 (33%), Gaps = 46/242 (19%)
Query: 3177 WPCAEGEPTWSPWTPWSQCSASCGPA---RCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
W + P W P W +C SC R ++ P T P P
Sbjct: 3041 WGGSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP- 3098
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
PE+ + C+L C GGG R C + L Y
Sbjct: 3099 ---PESFFKGCVLDVC------------------MGGG--DRDILC-----KALASYVAA 3130
Query: 3294 PRAQGEVCQALPCPV-TNCTAIEGAEYSPCGPPCPRSCDDLVH------CVWRCQPGCYC 3346
+A G V + V T E + Y CGPPCP SC C C GC C
Sbjct: 3131 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC 3190
Query: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CTCLE--GRLNCTDL 3403
G VLS++ + + G C C G H G+ C+ C C G L CT
Sbjct: 3191 DAGFVLSADRCVPLNNG-CGC--WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA 3247
Query: 3404 PC 3405
C
Sbjct: 3248 SC 3249
Score = 55.5 bits (132), Expect = 1e-06
Identities = 69/260 (26%), Positives = 92/260 (35%), Gaps = 39/260 (15%)
Query: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 4212 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 4268
Query: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLR 4027
RL Y PG G L++ F A P + + C GGG R
Sbjct: 4269 DRLEQYEGPGFCGP-----LSSGTGGPFTTCHAHVPPESFFKGCVLDVC---MGGGD--R 4318
Query: 4028 SRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC---SD 4081
C + S AG E +A+ + CE CP C CP C +
Sbjct: 4319 DILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSPAP 4374
Query: 4082 LQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQHQ 4134
L VC+ C +GC+C G + CVP+ + C C +A WA G+ Q
Sbjct: 4375 LTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 4432
Query: 4135 DACNNCSCQAGQLSCTAQPC 4154
C G L CT C
Sbjct: 4433 WC--RCGPGGGSLVCTPASC 4450
Score = 55.1 bits (131), Expect = 2e-06
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 13/95 (13%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
C C A C C EGC+C G L + C+P+ +C C P + L+ N
Sbjct: 2746 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDN 2805
Query: 2695 C-SQCVCEKGEL------------LCQPGGCPLPC 2716
C QC C G++ +CQP G L C
Sbjct: 2806 CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSC 2840
Score = 55.1 bits (131), Expect = 2e-06
Identities = 56/211 (26%), Positives = 68/211 (32%), Gaps = 57/211 (27%)
Query: 3248 GCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQP---------------------PPQG 3286
G RA GW P W C SC R + P PP+
Sbjct: 4244 GSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPES 4302
Query: 3287 LG-----DYCEGPRAQGEVCQALPCPVTNCTAI------------------EGAEYSPCG 3323
D C G + +C+AL V C A E + Y CG
Sbjct: 4303 FFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG 4362
Query: 3324 PPCPRSCDDLVH------CVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHH 3377
PPCP SC C C GC C G VLS++ + + G C C G H
Sbjct: 4363 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNG-CGC--WANGTYHE 4419
Query: 3378 PGARLARPDGCNH-CTCLE--GRLNCTDLPC 3405
G+ C+ C C G L CT C
Sbjct: 4420 AGSEFWADGTCSQWCRCGPGGGSLVCTPASC 4450
Score = 54.7 bits (130), Expect = 2e-06
Identities = 39/125 (31%), Positives = 46/125 (36%), Gaps = 11/125 (8%)
Query: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
CP CP C +CP C + C PC GC C G + G CVP ++C
Sbjct: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 800
Query: 4874 CTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVA 4933
CT L L E A EL RC C+G + D Q P V
Sbjct: 801 CTFQGLQ--LAPGQEVWADELCQ--------RRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
Query: 4934 PGELG 4938
G LG
Sbjct: 851 NGLLG 855
Score = 54.7 bits (130), Expect = 2e-06
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 13/95 (13%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
C C A C C EGC+C G L + C+P+ +C C P + L+ N
Sbjct: 3947 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDN 4006
Query: 2695 C-SQCVCEKGEL------------LCQPGGCPLPC 2716
C QC C G++ +CQP G L C
Sbjct: 4007 CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSC 4041
Score = 54.7 bits (130), Expect = 2e-06
Identities = 68/233 (29%), Positives = 81/233 (34%), Gaps = 57/233 (24%)
Query: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
C S PC SP TP Q S GP C + +T PL P
Sbjct: 4645 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 4683
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
P + CLL C G G P + + AC Q LG++
Sbjct: 4684 LVPPAQYFQGCLLDACQVQGHPGGLCP----------AVATYVAACQAAGAQ-LGEW--- 4729
Query: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQ 3350
+ + C L CP + Y CG CP SC L C C+ GC C G
Sbjct: 4730 --RRPDFCP-LQCPAHS-------HYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGF 4779
Query: 3351 VLSSNGAICVQPGHCSCLD----LLTGQRHHPGARLARPDGC---NHCTCLEG 3396
VLS G CV G C CL G+ +PG R C H TC EG
Sbjct: 4780 VLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 4830
Score = 54.3 bits (129), Expect = 3e-06
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 9/126 (7%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C C C+ L C C +GC C L G C+P+ C
Sbjct: 5117 CPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDC 5174
Query: 4118 DCTDAQGHSWAPGSQHQDACN-NCSCQAGQ-LSCTAQPCPPPTHC-----AWSHWSAWSP 4170
CT + S C+ CSC + L+C A CPP C A + W+
Sbjct: 5175 GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL 5234
Query: 4171 CSHSCG 4176
C S G
Sbjct: 5235 CVLSVG 5240
Score = 53.9 bits (128), Expect = 4e-06
Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 9/100 (9%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C + CG C G C + + + C+ C+ GC C G + C+P +C C H
Sbjct: 2337 CPAHSHYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLH 2394
Query: 4483 TSA-AGAGMTLAPGDRLQLGCKE-CECRR-GELHCTSQGC 4519
G T PG GC C CR GE+ C C
Sbjct: 2395 DDRYYPLGQTFYPGP----GCDSLCRCREGGEVSCEPSSC 2430
Score = 53.9 bits (128), Expect = 4e-06
Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 9/100 (9%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C + CG C G C + + + C+ C+ GC C G + C+P +C C H
Sbjct: 3538 CPAHSHYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLH 3595
Query: 4483 TSA-AGAGMTLAPGDRLQLGCKE-CECRR-GELHCTSQGC 4519
G T PG GC C CR GE+ C C
Sbjct: 3596 DDRYYPLGQTFYPGP----GCDSLCRCREGGEVSCEPSSC 3631
Score = 53.9 bits (128), Expect = 4e-06
Identities = 61/243 (25%), Positives = 80/243 (32%), Gaps = 33/243 (13%)
Query: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 4626 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 4685
Query: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
P Q +G C ++A C +Q + C QCP + +
Sbjct: 4686 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHY 4745
Query: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
E C G CP C + C C GC C G L +C+P QC C G+
Sbjct: 4746 ---ELC---GDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 4799
Query: 2953 LYASGAM-------ARLDSC---NNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCN 3002
Y G + R C + TC G E C + G C N
Sbjct: 4800 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 4859
Query: 3003 VGI 3005
GI
Sbjct: 4860 GGI 4862
Score = 53.5 bits (127), Expect = 5e-06
Identities = 57/200 (28%), Positives = 70/200 (35%), Gaps = 28/200 (14%)
Query: 3477 PWGPWSPC--DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQS 3534
P GP C D+CLG + S CS G H + P + + +C
Sbjct: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVE--PWRTETFCPMECPPNSH 1537
Query: 3535 LHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QY 3589
C C C LS CQ G C C C G L CVP C C Y
Sbjct: 1538 YELCADTCSLGCSALSAPPQCQDG---CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYY 1594
Query: 3590 QPGAMGIPENQSRS----AGSRFSSWE-SLEPGEVVTGPCDNCTCVAGILQCQEVPDCPD 3644
+P + +N + AG E S +PG+V C GIL C V P
Sbjct: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQV-------CQPSGGILSC--VTKDPC 1645
Query: 3645 PGVWSSWGPWEDCSVSCGGG 3664
GV + P E C G G
Sbjct: 1646 HGV--TCRPQETCKEQGGQG 1663
Score = 53.5 bits (127), Expect = 5e-06
Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 26/213 (12%)
Query: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 2224 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 2283
Query: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
P Q +G C ++A C +Q R+ C QCP + +
Sbjct: 2284 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHY 2343
Query: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
E C G CP C + C C GC C G L +C+P QC C +
Sbjct: 2344 ---ELC---GDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDR 2397
Query: 2953 LYASG-AMARLDSCNN-CTC-VSGKMACTSERC 2982
Y G C++ C C G+++C C
Sbjct: 2398 YYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 2430
Score = 53.5 bits (127), Expect = 5e-06
Identities = 68/242 (28%), Positives = 83/242 (34%), Gaps = 64/242 (26%)
Query: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
C S PC SP TP Q S GP C + +T PL P
Sbjct: 2243 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 2281
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGP----WSHCSRSCGGGLRSRTRACDQPPPQGLGD 3289
P + CLL C G G P + ++ G LR R D
Sbjct: 2282 LVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP----------D 2331
Query: 3290 YCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYC 3346
+C CP + Y CG CP SC L C C+ GC C
Sbjct: 2332 FCP-----------FQCPAHS-------HYELCGDSCPGSCPSLSAPEGCESACREGCVC 2373
Query: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP-DGCNH-CTCLE-GRLNCTDL 3403
G VLS G CV G C CL R++P + P GC+ C C E G ++C
Sbjct: 2374 DAGFVLS--GDTCVPVGQCGCLH---DDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPS 2428
Query: 3404 PC 3405
C
Sbjct: 2429 SC 2430
Score = 53.5 bits (127), Expect = 5e-06
Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 26/213 (12%)
Query: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 3425 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 3484
Query: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
P Q +G C ++A C +Q R+ C QCP + +
Sbjct: 3485 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHY 3544
Query: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
E C G CP C + C C GC C G L +C+P QC C +
Sbjct: 3545 ---ELC---GDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDR 3598
Query: 2953 LYASG-AMARLDSCNN-CTC-VSGKMACTSERC 2982
Y G C++ C C G+++C C
Sbjct: 3599 YYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 3631
Score = 53.5 bits (127), Expect = 5e-06
Identities = 68/242 (28%), Positives = 83/242 (34%), Gaps = 64/242 (26%)
Query: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
C S PC SP TP Q S GP C + +T PL P
Sbjct: 3444 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 3482
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGP----WSHCSRSCGGGLRSRTRACDQPPPQGLGD 3289
P + CLL C G G P + ++ G LR R D
Sbjct: 3483 LVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP----------D 3532
Query: 3290 YCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYC 3346
+C CP + Y CG CP SC L C C+ GC C
Sbjct: 3533 FCP-----------FQCPAHS-------HYELCGDSCPGSCPSLSAPEGCESACREGCVC 3574
Query: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP-DGCNH-CTCLE-GRLNCTDL 3403
G VLS G CV G C CL R++P + P GC+ C C E G ++C
Sbjct: 3575 DAGFVLS--GDTCVPVGQCGCLH---DDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPS 3629
Query: 3404 PC 3405
C
Sbjct: 3630 SC 3631
Score = 53.5 bits (127), Expect = 5e-06
Identities = 59/224 (26%), Positives = 77/224 (34%), Gaps = 40/224 (17%)
Query: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 4632 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 4688
Query: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
G + +G PG VA CQA + + CP +CP C
Sbjct: 4689 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC 4748
Query: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 4749 GDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPL---- 4803
Query: 4888 EEQAQELPPGTVLTRNCT-----RCVCHGGAFSCSLVDCQVPPG 4926
+ PG R C C GA +C++ G
Sbjct: 4804 ---GEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
Score = 53.1 bits (126), Expect = 7e-06
Identities = 62/242 (25%), Positives = 79/242 (32%), Gaps = 46/242 (19%)
Query: 3177 WPCAEGEPTWSPWTPWSQCSASCGPA---RCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
W + P W P W +C SC R ++ P T P P
Sbjct: 1840 WGGSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP- 1897
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
PE+ + C+L C GGG R C + L Y
Sbjct: 1898 ---PESFFKGCVLDVC------------------MGGG--DRDILC-----KALASYVAA 1929
Query: 3294 PRAQGEVCQALPCPV-TNCTAIEGAEYSPCGPPCPRSCDDLVH------CVWRCQPGCYC 3346
+A G V + V T E + Y CG PCP SC C C GC C
Sbjct: 1930 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQC 1989
Query: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CTCLE--GRLNCTDL 3403
G VLS++ + + G C C G H G+ C+ C C G L CT
Sbjct: 1990 DAGFVLSADRCVPLNNG-CGC--WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA 2046
Query: 3404 PC 3405
C
Sbjct: 2047 SC 2048
Score = 52.8 bits (125), Expect = 9e-06
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 18/118 (15%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLHNASCL 2940
C CP N + E C G CP C C+G C GC C PG +C+
Sbjct: 741 CPLSCPANSRY---ELC---GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACV 794
Query: 2941 PRSQCPCQLHG-------QLYASGAMARLDSCNNC----TCVSGKMACTSERCPVACG 2987
P S C C G +++A R +CN TC + ERC V G
Sbjct: 795 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNG 852
Score = 52.8 bits (125), Expect = 9e-06
Identities = 58/233 (24%), Positives = 75/233 (32%), Gaps = 55/233 (23%)
Query: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 4652 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 4701
Query: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
G P CP T CQ Q + C CG CP SC LS
Sbjct: 4702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 4761
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
C+ C+ C C G + CVP C C + G +
Sbjct: 4762 PEGCESA---CREGCVCDAGFVLSGDTCVPVGQCGCLHD--------------GRYYPLG 4804
Query: 3612 ESLEPGEVVTGPCD-NCTC-VAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCG 3662
E PG C+ C C G + CQE C GP E+C + G
Sbjct: 4805 EVFYPGP----ECERRCECGPGGHVTCQEGAAC---------GPHEECRLEDG 4844
Score = 52.8 bits (125), Expect = 9e-06
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
C SC C+ C EGC C LL C+P+ +C C S L +
Sbjct: 5134 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 5193
Query: 2695 CSQ-CVCEKGE-LLCQPGGCP 2713
CS+ C C L CQ GCP
Sbjct: 5194 CSERCSCSSSSGLTCQAAGCP 5214
Score = 52.4 bits (124), Expect = 1e-05
Identities = 64/241 (26%), Positives = 85/241 (35%), Gaps = 35/241 (14%)
Query: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC-PVLGPWSA-----WSSCSAP 4778
CG +L A QL +N + P +EC L P A + C P
Sbjct: 1040 CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
Query: 4779 CGGGTMERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCW 4836
G + C+ A CQA + + CP CPP AC+ CP C
Sbjct: 1100 GQSGPL-----CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1154
Query: 4837 HLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPP 4896
L C E C GC C G L +C+P +C C T Q P
Sbjct: 1155 DLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGCVHQG-------TYHPPGQTFYP 1206
Query: 4897 GTVLTRNC-TRCVC-HGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQS 4954
G C + C C GG SC C P E Q + G LG C+ + ++ Q+
Sbjct: 1207 GP----GCDSLCHCQEGGLVSCESSSC--GPHEACQP-SGGSLG-----CVAVGSSTCQA 1254
Query: 4955 N 4955
+
Sbjct: 1255 S 1255
Score = 52.0 bits (123), Expect = 2e-05
Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 27/140 (19%)
Query: 3289 DYCEGPRAQGEVCQALPCPVTNCTAIEG------------------AEYSPCGPPCPRSC 3330
D C P G +C AL C A + Y C CP SC
Sbjct: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSC 1153
Query: 3331 DDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDG 3387
DL C C GC C G LS G C+ C C+ G H PG G
Sbjct: 1154 GDLPVPGGCGSECHEGCVCDEGFALS--GESCLPLASCGCVH--QGTYHPPGQTFYPGPG 1209
Query: 3388 CNH-CTCLEGRL-NCTDLPC 3405
C+ C C EG L +C C
Sbjct: 1210 CDSLCHCQEGGLVSCESSSC 1229
Score = 51.6 bits (122), Expect = 2e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 4735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 4792
Query: 4118 DCTD-----AQGHSWAPGSQHQDACNNCSC-QAGQLSC-TAQPCPPPTHC 4160
C G + PG + + C C G ++C C P C
Sbjct: 4793 GCLHDGRYYPLGEVFYPGPECE---RRCECGPGGHVTCQEGAACGPHEEC 4839
Score = 51.2 bits (121), Expect = 3e-05
Identities = 54/213 (25%), Positives = 69/213 (32%), Gaps = 32/213 (15%)
Query: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 2250 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 2299
Query: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
G P CP T CQ Q + C CG CP SC LS
Sbjct: 2300 QGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSA 2359
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
C+ C+ C C G + CVP C C + + + G S
Sbjct: 2360 PEGCES---ACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD-SLC 2415
Query: 3612 ESLEPGEV-----VTGPCDNCTCVAGILQCQEV 3639
E GEV GP + C G L C V
Sbjct: 2416 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAV 2448
Score = 51.2 bits (121), Expect = 3e-05
Identities = 54/213 (25%), Positives = 69/213 (32%), Gaps = 32/213 (15%)
Query: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 3451 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 3500
Query: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
G P CP T CQ Q + C CG CP SC LS
Sbjct: 3501 QGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSA 3560
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
C+ C+ C C G + CVP C C + + + G S
Sbjct: 3561 PEGCES---ACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD-SLC 3616
Query: 3612 ESLEPGEV-----VTGPCDNCTCVAGILQCQEV 3639
E GEV GP + C G L C V
Sbjct: 3617 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAV 3649
Score = 50.8 bits (120), Expect = 3e-05
Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 17/116 (14%)
Query: 3291 CEGPRAQGEVCQALPCPV------TNC--TAIEGAEYSPCGPPCPRSCDDLV---HCVWR 3339
C G A + C L V NC + + Y CGP CP SC+ +C R
Sbjct: 715 CRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR 774
Query: 3340 -CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGC-NHCTC 3393
C GC C PG V S G CV C C G + PG + + C CTC
Sbjct: 775 PCVEGCVCLPGFVAS--GGACVPASSCGC--TFQGLQLAPGQEVWADELCQRRCTC 826
Score = 50.8 bits (120), Expect = 3e-05
Identities = 65/247 (26%), Positives = 80/247 (32%), Gaps = 36/247 (14%)
Query: 3437 CPTPQHGGAPCTGEAGEAGAQHQRE---ACPSYATCPVDGAW---GPWGPWSPC--DMCL 3488
CP G P E ++Q+E S T P+ P GP C D+CL
Sbjct: 3836 CPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 3895
Query: 3489 GQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCT-DCGGGQSLHPCGQPCPRSCQ 3547
G + S CS G H + N T C +C C C C
Sbjct: 3896 GGGNLSILCSNIHAYVSACQAAGGHVEP---WRNETFCPMECPQNSHYELCADTCSLGCS 3952
Query: 3548 DLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QYQPGAMGIPENQSR 3602
LS C G C C C G L CVP C C Y+P + +N +
Sbjct: 3953 ALSAPLQCPDG---CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 4009
Query: 3603 SAGSRFS-----SWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDC 3657
S +PG+V C GIL C V P GV + P E C
Sbjct: 4010 QCTCHVGKVVVCQEHSCKPGQV-------CQPSGGILSC--VTKDPCHGV--TCRPQETC 4058
Query: 3658 SVSCGGG 3664
G G
Sbjct: 4059 KEQGGQG 4065
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 1963 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 2021
Query: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
W + S C G + C+P +C GE L P C P E P
Sbjct: 2022 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2081
Query: 5055 LLTELRNFTKGTC 5067
L R +GTC
Sbjct: 2082 TLDGHRFNFQGTC 2094
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 3164 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 3222
Query: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
W + S C G + C+P +C GE L P C P E P
Sbjct: 3223 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 3282
Query: 5055 LLTELRNFTKGTC 5067
L R +GTC
Sbjct: 3283 TLDGHRFDFQGTC 3295
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 4365 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 4423
Query: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
W + S C G + C+P +C GE L P C P E P
Sbjct: 4424 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 4483
Query: 5055 LLTELRNFTKGTC 5067
L R +GTC
Sbjct: 4484 TLDGHRFDFQGTC 4496
Score = 49.7 bits (117), Expect = 8e-05
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 2633 PPCPPSCLDPKANRSCSGH-CVEGCRCPPGLLLHDTRCLPLSECPC 2677
P CP SC A +CSG CVEGC C PG + C+P S C C
Sbjct: 756 PACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Score = 49.7 bits (117), Expect = 8e-05
Identities = 159/676 (23%), Positives = 209/676 (30%), Gaps = 146/676 (21%)
Query: 1277 GGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWG 1336
G V + C C P E P C V++ +G P HG
Sbjct: 2241 GECVSKPCPSPCTPEQQESFGGPD-ACGVISATDGPLAP----CHG-------------- 2281
Query: 1337 RNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENG--------- 1387
PP Q C CQ Q H GG L PA A A CQ G
Sbjct: 2282 --LVPPAQYFQ-GCLLDACQV-QGHPGG-------LCPAVATYVAACQAAGAQLREWRRP 2330
Query: 1388 -----HCVPHGW--LCDNQ--DDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQ 1438
C H LC + C S EGC + C EG C +G L C
Sbjct: 2331 DFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCES-ACREG-CVCDAGFVLS-GDTCVPV 2387
Query: 1439 DDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVS 1498
CG D+ YP G+ P CD C + GEVS
Sbjct: 2388 GQCGCLHDDRYYPL---------GQTFYPGPGCDSLCRCREG--------------GEVS 2424
Query: 1499 CVDGTCLGAIQLCDGVWDCPDGADEG---PGHCPLPSLPTPPASTLPGPSPGSLDTASSP 1555
C +C G + C P G G G + P +T G + T
Sbjct: 2425 CEPSSC-GPHETCR-----PSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYV 2478
Query: 1556 LASASPAPPCGPFEFRC-------GSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHA 1608
LA P G F G+G + Q + ++R
Sbjct: 2479 LAQTCGTRP-GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR--------QWK 2529
Query: 1609 PCARGPHCVSPEQLCDG-VRQCPDGSDEGPDACGGLPA---LGGPNRTGLPCPEYTCPNG 1664
G P L +G +R GSD + GL L R +P Y G
Sbjct: 2530 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 2589
Query: 1665 TCIGFQLVCDGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPC--SRTCGPWGQGRSRRCS 1722
C + D + D +P + +W P PC TC P +G C
Sbjct: 2590 LCGNYN--GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEG----CI 2643
Query: 1723 PLGLLVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCS--------------EPCRG 1768
P + CP PE + + C + S P S C + C G
Sbjct: 2644 PS-----EECP-PELEKKYQKEEFCGLLS--SPTGPLSSCHKLVDPQGPLKDCIFDLCLG 2695
Query: 1769 TMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLT 1827
C + C A G + R CP + C ++ CA C L
Sbjct: 2696 GGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPME------CPQNSHYELCADTCSLG 2749
Query: 1828 CDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD- 1886
C +S + CP + GC C G + + CV +QC C +GA Y P Q + D
Sbjct: 2750 CSALSAPLQCPDGC---AEGCQCDSGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLIDN 2805
Query: 1887 C-QLCICQDGRPRRCR 1901
C Q C C G+ C+
Sbjct: 2806 CRQQCTCHVGKVVVCQ 2821
Score = 49.7 bits (117), Expect = 8e-05
Identities = 65/243 (26%), Positives = 76/243 (31%), Gaps = 28/243 (11%)
Query: 3437 CPTPQHGGAPCTGEAGEAGAQHQRE---ACPSYATCPVDGAW---GPWGPWSPC--DMCL 3488
CP G P E ++Q+E S T P+ P GP C D+CL
Sbjct: 2635 CPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 2694
Query: 3489 GQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCT-DCGGGQSLHPCGQPCPRSCQ 3547
G + S CS G + N T C +C C C C
Sbjct: 2695 GGGNLSILCSNIHAYVSACQAAGGQVEP---WRNETFCPMECPQNSHYELCADTCSLGCS 2751
Query: 3548 DLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSR 3607
LS C G C C C G L CVP C C Y GA PE R
Sbjct: 2752 ALSAPLQCPDG---CAEGCQCDSGFLYNGQACVPIQQCGC-YHNGAYYEPEQTVLIDNCR 2807
Query: 3608 FSSWESLEPGEVVT------GPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSC 3661
+ G+VV P C GIL C DP + P E C
Sbjct: 2808 QQC--TCHVGKVVVCQEHSCKPGQVCQPSGGILSCVN----KDPCHGVTCRPQETCKEQG 2861
Query: 3662 GGG 3664
G G
Sbjct: 2862 GQG 2864
Score = 48.5 bits (114), Expect = 2e-04
Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 10/121 (8%)
Query: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
C GH P C + C C+ C+ + C D C GC C
Sbjct: 3914 CQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD--GCAEGCQCD 3971
Query: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL-GCK-ECECRRGE-LHCTSQGC 4519
G L C+P ++C C+H G+ P + + C+ +C C G+ + C C
Sbjct: 3972 SGFLYNGQACVPIQQCGCYHN-----GVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026
Query: 4520 Q 4520
+
Sbjct: 4027 K 4027
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CP SC A C C EGC C G +L C+P+ +C CL G F G
Sbjct: 4752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 4811
Query: 2695 CSQCVCEKGELLCQPGG 2711
+ CE C PGG
Sbjct: 4812 ECERRCE-----CGPGG 4823
Score = 47.4 bits (111), Expect = 4e-04
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 19/144 (13%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPC 3144
P CP + ++ C P SC +AP + + C GC C G + CVP C C
Sbjct: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Query: 3145 AHEGHLYPPGSTV------VRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSAS 3198
+G PG V R C C+ + + C GE +CS
Sbjct: 802 TFQGLQLAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAGE----------RCSVQ 850
Query: 3199 CGPARCHRHRFCARSPSAVPSTVA 3222
G C+ RF S P V+
Sbjct: 851 NGLLGCYPDRFGTCQGSGDPHYVS 874
Score = 47.4 bits (111), Expect = 4e-04
Identities = 35/115 (30%), Positives = 45/115 (39%), Gaps = 13/115 (11%)
Query: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
E +C + CGSPC C A + +C+ PC GC C G + A C+P
Sbjct: 1947 EITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 2004
Query: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
C CW + + AG C+ C G L CT C GLLP
Sbjct: 2005 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 2058
Score = 47.4 bits (111), Expect = 4e-04
Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 9/130 (6%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
C SLA C + T C CP + + + Q G C L G
Sbjct: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ--GSCAALSGLTG-- 5146
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ-LYASGAMARLDSCNNCTCVSGK 2974
CT C GC C L C+P C C +G+ L + ++ D C+C S
Sbjct: 5147 --CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 5204
Query: 2975 -MACTSERCP 2983
+ C + CP
Sbjct: 5205 GLTCQAAGCP 5214
Score = 47.0 bits (110), Expect = 5e-04
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 37/230 (16%)
Query: 4836 WHLQPGAICVQEPCQPGC-GCPGGQLLH---NGTCV-------PPTACPCTQHSLPWGLT 4884
W L G ++ CQ C C GQ H + C P C T P+
Sbjct: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPF--- 696
Query: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHG-GAFSCSLVDCQVPPGETWQQVAPGELG----- 4938
LE+ +L + +C G A++ + ++ + G+ W+ A L
Sbjct: 697 --LEQCVYDL----CVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLSCPANS 749
Query: 4939 ---LCEQTC-LEMNATKTQSNCSSARA-SGCVCQPGHFRSQAGPCVPEDHCECWHLGRPH 4993
LC C N SNCS GCVC PG F + G CVP C C G
Sbjct: 750 RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQL 808
Query: 4994 LPGSE-W-QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG--SCCP 5039
PG E W E C+ +G +C GE ++ G C P
Sbjct: 809 APGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
Score = 47.0 bits (110), Expect = 5e-04
Identities = 49/189 (25%), Positives = 66/189 (34%), Gaps = 42/189 (22%)
Query: 3599 NQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP-----------GV 3647
+Q+ +A +SWE + P P TC G C +CP G+
Sbjct: 2608 SQAGNANEFGNSWEEVVPDSPCLPPP---TCPPGSEGCIPSEECPPELEKKYQKEEFCGL 2664
Query: 3648 WSS-WGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCST-----QVCREAG----- 3696
SS GP C L+ C C G S CS C+ AG
Sbjct: 2665 LSSPTGPLSSCHKLVDPQGPLKD--CIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEP 2722
Query: 3697 ----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA 3746
CP Y C + C C+ ++ + C +GC EGC C G + A
Sbjct: 2723 WRNETFCPMECPQNSHYELC--ADTCSLGCSALSAPLQC-PDGCAEGCQCDSGFLYNGQA 2779
Query: 3747 CV--QECPC 3753
CV Q+C C
Sbjct: 2780 CVPIQQCGC 2788
Score = 47.0 bits (110), Expect = 5e-04
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 13/126 (10%)
Query: 4642 AEALCGGGCREPWAQESCNGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPC 4700
A G +PW +S CP C A C C SCA L C C
Sbjct: 5099 AACQAAGVAVKPWRTDSF----CPLHCPAHSHYSI--CTRTCQGSCAALSGLTGCTTR-C 5151
Query: 4701 RPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDC-QNCTCVNES-LVC 4758
GC C L+ G C+P+ C C + N + + + DC + C+C + S L C
Sbjct: 5152 FEGCECDDRFLLSQGVCIPVQDCGC---THNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 5208
Query: 4759 PHQECP 4764
CP
Sbjct: 5209 QAAGCP 5214
Score = 46.6 bits (109), Expect = 6e-04
Identities = 48/181 (26%), Positives = 66/181 (36%), Gaps = 25/181 (13%)
Query: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 1953
Query: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
C + CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 1954 SHYEVCGSPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 2012
Query: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 2013 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 2062
Query: 4938 G 4938
G
Sbjct: 2063 G 2063
Score = 46.6 bits (109), Expect = 6e-04
Identities = 49/189 (25%), Positives = 65/189 (34%), Gaps = 42/189 (22%)
Query: 3599 NQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP-----------GV 3647
+Q+ +A +SWE + P P TC G C CP G+
Sbjct: 3809 SQAGNANEFGNSWEEVVPDSPCLPPP---TCPPGSAGCIPSDKCPPELEKKYQKEEFCGL 3865
Query: 3648 WSS-WGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCST-----QVCREAG----- 3696
SS GP C L+ C C G S CS C+ AG
Sbjct: 3866 LSSPTGPLSSCHKLVDPQGPLKD--CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEP 3923
Query: 3697 ----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA 3746
CP Y C + C C+ ++ + C +GC EGC C G + A
Sbjct: 3924 WRNETFCPMECPQNSHYELC--ADTCSLGCSALSAPLQC-PDGCAEGCQCDSGFLYNGQA 3980
Query: 3747 CV--QECPC 3753
CV Q+C C
Sbjct: 3981 CVPIQQCGC 3989
Score = 46.6 bits (109), Expect = 6e-04
Identities = 35/119 (29%), Positives = 49/119 (41%), Gaps = 13/119 (10%)
Query: 1786 CAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCG 1844
C A G + R CP + C ++ CA C L C +S + CP
Sbjct: 3914 CQAAGGHVEPWRNETFCPME------CPQNSHYELCADTCSLGCSALSAPLQCPDGC--- 3964
Query: 1845 SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD-C-QLCICQDGRPRRCR 1901
+ GC C G + + CV +QC C +G Y P Q + D C Q C C G+ C+
Sbjct: 3965 AEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQ 4022
Score = 46.6 bits (109), Expect = 6e-04
Identities = 49/194 (25%), Positives = 65/194 (33%), Gaps = 31/194 (15%)
Query: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
A CQA + CP CP S C +C C L C C GC C
Sbjct: 5099 AACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCEC 5157
Query: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELP-PGTVLTRNCT-RCVCHGGA 4913
LL G C+P C CT + + LP ++LT +C+ RC C +
Sbjct: 5158 DDRFLLSQGVCIPVQDCGCTHN-------------GRYLPVNSSLLTSDCSERCSCSSSS 5204
Query: 4914 -FSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFR 4972
+C C PPG +CE N T+ C + + G
Sbjct: 5205 GLTCQAAGC--PPGR-----------VCEVKAEARNCWATRGLCVLSVGANLTTFDGARG 5251
Query: 4973 SQAGPCVPEDHCEC 4986
+ P V E C
Sbjct: 5252 ATTSPGVYELSSRC 5265
Score = 45.8 bits (107), Expect = 0.001
Identities = 38/158 (24%), Positives = 52/158 (32%), Gaps = 23/158 (14%)
Query: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
C G P C + C C+ C+ + C D C GC C
Sbjct: 2713 CQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD--GCAEGCQCD 2770
Query: 4463 KGLLEQAGGCIPPEECNCWHTSA--AGAGMTLAPGDRLQ--------LGCKECECRRGEL 4512
G L C+P ++C C+H A L R Q + C+E C+ G++
Sbjct: 2771 SGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQV 2830
Query: 4513 HCTSQG---------CQGLL--PLSEWSEWSPCGPCLP 4539
S G C G+ P E G CLP
Sbjct: 2831 CQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLP 2868
Score = 45.8 bits (107), Expect = 0.001
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 25/181 (13%)
Query: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 3099 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 3154
Query: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
C CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 3155 SHYEVCGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 3213
Query: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 3214 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 3263
Query: 4938 G 4938
G
Sbjct: 3264 G 3264
Score = 45.8 bits (107), Expect = 0.001
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 25/181 (13%)
Query: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 4300 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 4355
Query: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
C CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 4356 SHYEVCGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 4414
Query: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 4415 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 4464
Query: 4938 G 4938
G
Sbjct: 4465 G 4465
Score = 45.8 bits (107), Expect = 0.001
Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
C +C ++A + C SA GCVC G F CVP C C H LG
Sbjct: 4752 CPVSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVF 4807
Query: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG 5035
PG E + CE C G V Q + C EE LE G
Sbjct: 4808 YPGPECERRCE---CGPGGHVTCQEGA--ACGPHEECRLEDG 4844
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 1807 CPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWP 1865
CP +C ++ C P CP +C+ + C PC GC C G V S G CV
Sbjct: 741 CP-LSCPANSRYELCGPACPTSCNGAAAPSNCSGR-PCVE-GCVCLPGFV-ASGGACVPA 796
Query: 1866 RQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLN 1903
C C G + PGQ + AD +LC RRC N
Sbjct: 797 SSCGCTFQGLQLAPGQEVWAD-ELC------QRRCTCN 827
Score = 45.4 bits (106), Expect = 0.001
Identities = 41/121 (33%), Positives = 54/121 (44%), Gaps = 19/121 (15%)
Query: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
E W AQ C CPE + C + CP SC A L C +GPC GC+C
Sbjct: 1938 EDWRAQVGCEI-TCPENSHYEV-----CGSPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 1990
Query: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 1991 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2047
Query: 4763 C 4763
C
Sbjct: 2048 C 2048
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 31/111 (27%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
C +C ++A + C SA GCVC G F CVP C C H LG+
Sbjct: 2350 CPGSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDDRYYPLGQTF 2405
Query: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP--SCR 5042
PG P C C C +G E+ EP SC P +CR
Sbjct: 2406 YPG----------------PGCDSLC---RCREGGEVSCEPSSCGPHETCR 2437
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 3148 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 3205
Query: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
C CW + + AG C+ C G L CT C GLLP
Sbjct: 3206 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 3259
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 31/111 (27%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
C +C ++A + C SA GCVC G F CVP C C H LG+
Sbjct: 3551 CPGSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDDRYYPLGQTF 3606
Query: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP--SCR 5042
PG P C C C +G E+ EP SC P +CR
Sbjct: 3607 YPG----------------PGCDSLC---RCREGGEVSCEPSSCGPHETCR 3638
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 4349 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 4406
Query: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
C CW + + AG C+ C G L CT C GLLP
Sbjct: 4407 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 4460
Score = 45.1 bits (105), Expect = 0.002
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 15/106 (14%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
CPA Y C P CP SC C C EGC C G ACV C
Sbjct: 745 CPANSRYELCGPA--CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSC--- 799
Query: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
G T G L PG E+ + + + C C+ A +++C
Sbjct: 800 -------GCTF--QGLQLAPGQEVWADELCQRRC-TCNGATHQVTC 835
Score = 45.1 bits (105), Expect = 0.002
Identities = 37/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%)
Query: 1786 CAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCG 1844
C A G + R CP + PN+ ++ CA C L C +S PP G
Sbjct: 1512 CQAAGGHVEPWRTETFCPMECPPNSH------YELCADTCSLGCSALSA----PPQCQDG 1561
Query: 1845 -SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD-C-QLCICQDGRPRRCR 1901
+ GC C G + + CV +QC C +G Y P Q + D C Q C C G+ C+
Sbjct: 1562 CAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
Score = 45.1 bits (105), Expect = 0.002
Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 76/269 (28%)
Query: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 2218 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 2277
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
P G+ ++ C + C PG + C+ AG
Sbjct: 2278 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLREW 2327
Query: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 2328 RRPDFCPFQCPAHSHYELC--GDSCPGSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 2384
Query: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSCGNCSCAH-GKLSC 3802
V C G D PLG PG DS C C G++SC
Sbjct: 2385 VPVGQC----------GCLHDDRYYPLGQTFYPGPGCDS---------LCRCREGGEVSC 2425
Query: 3803 SLDDCFEADGGFGPWSPWGPCSRSCGGLG 3831
C P C S G LG
Sbjct: 2426 EPSSC----------GPHETCRPSGGSLG 2444
Score = 45.1 bits (105), Expect = 0.002
Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 76/269 (28%)
Query: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 3419 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 3478
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
P G+ ++ C + C PG + C+ AG
Sbjct: 3479 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLREW 3528
Query: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 3529 RRPDFCPFQCPAHSHYELC--GDSCPGSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 3585
Query: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSCGNCSCAH-GKLSC 3802
V C G D PLG PG DS C C G++SC
Sbjct: 3586 VPVGQC----------GCLHDDRYYPLGQTFYPGPGCDS---------LCRCREGGEVSC 3626
Query: 3803 SLDDCFEADGGFGPWSPWGPCSRSCGGLG 3831
C P C S G LG
Sbjct: 3627 EPSSC----------GPHETCRPSGGSLG 3645
Score = 45.1 bits (105), Expect = 0.002
Identities = 51/222 (22%), Positives = 68/222 (30%), Gaps = 73/222 (32%)
Query: 4357 CYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAG-----APCTRL---DG 4408
C S PCP C +Q+ GP + G + APC L
Sbjct: 4645 CVSKPCPSPCT---------------PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 4689
Query: 4409 HFRPCLISNCS----EDSCTPPFEFHACGSPCAGL--------------CATHLSHQLCQ 4450
+F+ CL+ C P + AG C H ++LC
Sbjct: 4690 YFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCG 4749
Query: 4451 DLPP---------------CQPGCYCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAP 4494
D P C+ GC C G + C+P +C C H G P
Sbjct: 4750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYP 4809
Query: 4495 GDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGP 4536
G + + CEC G H T Q E + CGP
Sbjct: 4810 GPECE---RRCECGPGG-HVTCQ------------EGAACGP 4835
Score = 44.7 bits (104), Expect = 0.002
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 14/96 (14%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC-----GLPSANA 4732
C + CP SC L C + CR GC C G ++ CVP+ C C P
Sbjct: 4748 CGDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 4806
Query: 4733 SWELAPAQAVQLDCQ-----NCTCVNESLVCPHQEC 4763
+ P + C+ + TC + PH+EC
Sbjct: 4807 FY---PGPECERRCECGPGGHVTCQEGAACGPHEEC 4839
Score = 44.3 bits (103), Expect = 0.003
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 3139 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 3191
Query: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 3192 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 3248
Query: 4763 C 4763
C
Sbjct: 3249 C 3249
Score = 44.3 bits (103), Expect = 0.003
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 4340 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 4392
Query: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 4393 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 4449
Query: 4763 C 4763
C
Sbjct: 4450 C 4450
Score = 44.3 bits (103), Expect = 0.003
Identities = 148/650 (22%), Positives = 200/650 (30%), Gaps = 152/650 (23%)
Query: 3078 GLQPC----AGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH---PGCHCPSGML 3130
G Q C + P P C ++Q + GP +C +SA G CH P G L
Sbjct: 4638 GAQGCGECVSKPCPSPCTPEQQ--ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 4695
Query: 3131 LLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWT 3190
L C +GH PG C V+ +A C + GE W
Sbjct: 4696 L----------DACQVQGH---PGGL-------CPAVATYVAACQAAGAQLGE-----WR 4730
Query: 3191 PWSQCSASCGPARCHRHRFCARS-PSAVPSTVAPLPLPATPTPLC---SGPEAEEEPCLL 3246
C C PA H + C S P + PS AP + C +G + C+
Sbjct: 4731 RPDFCPLQC-PAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVP 4788
Query: 3247 QG---CDRAGGWGPWG----PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC---EGPRA 3296
G C G + P G P C R C G C + G + C +G +A
Sbjct: 4789 VGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHV-TCQEGAACGPHEECRLEDGVQA 4847
Query: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQ-----V 3351
C A C C A G Y R D C + C+ PG V
Sbjct: 4848 ----CHATGCG--RCLANGGIHYITLDG---RVYDLHGSCSYVLAQVCHPKPGDEDFSIV 4898
Query: 3352 LSSNGAICVQPGHCSC----LDLLTGQRHH-PGARLARPDGCNHC-TCLEGR---LNCT- 3401
L N A +Q + + L GQ+ G +A P EGR L T
Sbjct: 4899 LEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK 4958
Query: 3402 --------------DLPCPVPGGWCP--------WSE-WTMCSQPCRGQTRSRSRACACP 3438
+P P G C WS+ + + + + A P
Sbjct: 4959 GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAP 5018
Query: 3439 TPQHGGAPCTGEAG-------EAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQS 3491
G G G E EAC P GP++ C L S
Sbjct: 5019 GSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN--------PQGPFATCQAVLSPS 5070
Query: 3492 HRSRACSRPPTPEGG-------------RPCPGNHTQSRPCQENSTQCTDCGGGQSLHPC 3538
R C + G C +P + +S C C
Sbjct: 5071 EYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSIC 5130
Query: 3539 GQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPE 3598
+ C SC LS + C + C C C L G+C+P C C + +P
Sbjct: 5131 TRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTH--NGRYLPV 5185
Query: 3599 NQSRSAGSRFSSWESLEPGEVVTGPC-DNCTCVAGI-LQCQEVPDCPDPG 3646
N S ++T C + C+C + L CQ CP PG
Sbjct: 5186 NSS-----------------LLTSDCSERCSCSSSSGLTCQ-AAGCP-PG 5216
Score = 43.9 bits (102), Expect = 0.004
Identities = 48/189 (25%), Positives = 63/189 (33%), Gaps = 42/189 (22%)
Query: 3599 NQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP-----------GV 3647
+Q+ +A +SWE + P P C G C CP G+
Sbjct: 1407 SQAGNANEFGNSWEEVVPDSPCLPPTP---CPPGSEDCIPSHKCPPELEKKYQKEEFCGL 1463
Query: 3648 WSS-WGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCST-----QVCREAG----- 3696
SS GP C L+ C C G S CS C+ AG
Sbjct: 1464 LSSPTGPLSSCHKLVDPQGPLKD--CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEP 1521
Query: 3697 ----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA 3746
CP Y C + C C+ ++ C +GC EGC C G + A
Sbjct: 1522 WRTETFCPMECPPNSHYELC--ADTCSLGCSALSAPPQC-QDGCAEGCQCDSGFLYNGQA 1578
Query: 3747 CV--QECPC 3753
CV Q+C C
Sbjct: 1579 CVPIQQCGC 1587
Score = 43.1 bits (100), Expect = 0.007
Identities = 33/133 (24%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 2854 GRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQ 2912
G C +LA C + ++ C CP + + + CP C
Sbjct: 1103 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY------GCPLSCGDL 1156
Query: 2913 GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASG-AMARLDSCNN-CTC 2970
C C GC C G L SCLP + C C G + G C++ C C
Sbjct: 1157 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
Query: 2971 VSGKM-ACTSERC 2982
G + +C S C
Sbjct: 1217 QEGGLVSCESSSC 1229
Score = 43.1 bits (100), Expect = 0.007
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC 4725
C + CP SC L C + CR GC C G ++ CVP+ C C
Sbjct: 2346 CGDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGC 2392
Score = 43.1 bits (100), Expect = 0.007
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC 4725
C + CP SC L C + CR GC C G ++ CVP+ C C
Sbjct: 3547 CGDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGC 3593
Score = 42.7 bits (99), Expect = 0.009
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 14/105 (13%)
Query: 3486 MCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRS 3545
+C G S ++AC G P N S C CG CP S
Sbjct: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLS------------CPANSRYELCGPACPTS 761
Query: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ 3590
C + S C C C C G ++ G CVP + C C +Q
Sbjct: 762 CNGAAAPSNCSGRP--CVEGCVCLPGFVASGGACVPASSCGCTFQ 804
Score = 42.7 bits (99), Expect = 0.009
Identities = 58/252 (23%), Positives = 84/252 (33%), Gaps = 63/252 (25%)
Query: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 4620 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 4679
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
P G+ ++ C + C PG + C+ AG
Sbjct: 4680 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLGEW 4729
Query: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 4730 RRPDFCPLQCPAHSHYELC--GDSCPVSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 4786
Query: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSC---GNCSCAHGKL 3800
V C G PLG PG E + R C G+ +C G
Sbjct: 4787 VPVGQC----------GCLHDGRYYPLGEVFYPGPECER----RCECGPGGHVTCQEGAA 4832
Query: 3801 SCSLDDCFEADG 3812
++C DG
Sbjct: 4833 CGPHEECRLEDG 4844
Score = 42.0 bits (97), Expect = 0.016
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 6/84 (7%)
Query: 4642 AEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCR 4701
A G PW E CP + C+ CP SC DL C C
Sbjct: 1114 AACQAAGATVHPWRSEELCPLSCPPHSHYEA-----CSYGCPLSCGDLPVPGGC-GSECH 1167
Query: 4702 PGCRCPPGQLVQDGRCVPISSCRC 4725
GC C G + C+P++SC C
Sbjct: 1168 EGCVCDEGFALSGESCLPLASCGC 1191
Score = 41.6 bits (96), Expect = 0.021
Identities = 73/320 (22%), Positives = 95/320 (29%), Gaps = 94/320 (29%)
Query: 3057 GGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGPASCAELSAPRGT 3115
GGG S E + G C PG CP+ D Q C L+ P+G
Sbjct: 1018 GGGQAANALAFGNSWQEETRPG---CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
Query: 3116 NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCS 3175
+ CH P G + C ++ L P S + C ++ A C
Sbjct: 1075 FRECHSKLD-PQGAVR-----------DCVYDRCLLPGQSGPL-----CDALATYAAACQ 1117
Query: 3176 SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235
+ T PW C SC P H P + LP+P
Sbjct: 1118 A-----AGATVHPWRSEELCPLSCPP-----HSHYEACSYGCPLSCGDLPVP-------- 1159
Query: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPR 3295
GG G S C C CD EG
Sbjct: 1160 -----------------GGCG-----SECHEGC---------VCD-----------EGFA 1177
Query: 3296 AQGEVCQALPCPVTNCTAIEGAEYSPCGP---PCPRSCDDLVHC----VWRCQPGCYCPP 3348
GE C P+ +C + Y P G P P CD L HC + C+ P
Sbjct: 1178 LSGESC----LPLASCGCVHQGTYHPPGQTFYPGP-GCDSLCHCQEGGLVSCESSSCGPH 1232
Query: 3349 GQVLSSNGAI-CVQPGHCSC 3367
S G++ CV G +C
Sbjct: 1233 EACQPSGGSLGCVAVGSSTC 1252
Score = 41.6 bits (96), Expect = 0.021
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2009
Query: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
G + GS CS W C G S C PA
Sbjct: 2010 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 2047
Query: 3204 CHRHRFCARSPS 3215
C C PS
Sbjct: 2048 CGLGEVCGLLPS 2059
Score = 41.6 bits (96), Expect = 0.021
Identities = 38/140 (27%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 4933 APGELGLCEQTCL-EMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGR 4991
A +C +TC A + C++ GC C SQ G C+P C C H GR
Sbjct: 5123 AHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ-GVCIPVQDCGCTHNGR 5181
Query: 4992 PHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSP 5051
+LP S L S C++ CS C+ + + C P
Sbjct: 5182 -YLP-------VNSSLLTSD---CSERCS---CSSSSGLTCQAAGCPP----------GR 5217
Query: 5052 SCQLLTELRN--FTKGTCYL 5069
C++ E RN T+G C L
Sbjct: 5218 VCEVKAEARNCWATRGLCVL 5237
Score = 41.2 bits (95), Expect = 0.027
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 3210
Query: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
G + GS CS W C G S C PA
Sbjct: 3211 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 3248
Query: 3204 CHRHRFCARSPS 3215
C C PS
Sbjct: 3249 CGLGEVCGLLPS 3260
Score = 41.2 bits (95), Expect = 0.027
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 4411
Query: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
G + GS CS W C G S C PA
Sbjct: 4412 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 4449
Query: 3204 CHRHRFCARSPS 3215
C C PS
Sbjct: 4450 CGLGEVCGLLPS 4461
Score = 41.2 bits (95), Expect = 0.027
Identities = 34/111 (30%), Positives = 43/111 (38%), Gaps = 12/111 (10%)
Query: 3306 CPVTNCTAIEGAEYSPCGPPCPRSC---DDLVHCVWRCQPGCYCPPGQVLSSNGAICVQP 3362
CP+ +C A + YS C C SC L C RC GC C +LS +C+
Sbjct: 5117 CPL-HCPA--HSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVCIPV 5171
Query: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPGGWC 3412
C C G+ + L D C+C L C CP PG C
Sbjct: 5172 QDCGCTH--NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP-PGRVC 5219
Score = 40.8 bits (94), Expect = 0.035
Identities = 66/269 (24%), Positives = 87/269 (32%), Gaps = 72/269 (26%)
Query: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTN-QTCHPGCHCP-----SGMLLLNNV 3135
C G P CP D+ L+ +GP C LS+ G TCH H P G +L +V
Sbjct: 4259 CRGSCP-TCPEDR--LEQYEGPGFCGPLSSGTGGPFTTCH--AHVPPESFFKGCVL--DV 4311
Query: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
C+ D C ++ +A C + W C
Sbjct: 4312 CMGGGDRDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 4348
Query: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
+C P H P++ PS P P T +C GP E C + DR
Sbjct: 4349 EITC-PENSHYEVCGPPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 4402
Query: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
G G W ++ CS+ C G + C P GLG
Sbjct: 4403 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 4453
Query: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
EVC LP C + AE G P
Sbjct: 4454 --EVCGLLPSGQHGCQPVSTAECQAWGDP 4480
Score = 40.4 bits (93), Expect = 0.046
Identities = 53/203 (26%), Positives = 66/203 (32%), Gaps = 50/203 (24%)
Query: 3477 PWGPWSPCDMCLGQSHRSRAC--SRPPTP-EGGRPCPGNHTQSRPCQ---------ENST 3524
P GP+ C L R C R P + G C T + CQ +
Sbjct: 1071 PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEE 1130
Query: 3525 QCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVG--CQPTCGCPLGQLSQDGLCVP 3581
C C C CP SC DL PG G C C C G C+P
Sbjct: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPV-----PGGCGSECHEGCVCDEGFALSGESCLP 1185
Query: 3582 PAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTC-VAGILQCQEV 3639
A C C +Q G+ ++ PG CD+ C C G++ C+
Sbjct: 1186 LASCGCVHQ--------------GTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES- 1226
Query: 3640 PDCPDPGVWSSWGPWEDCSVSCG 3662
SS GP E C S G
Sbjct: 1227 ---------SSCGPHEACQPSGG 1240
Score = 40.0 bits (92), Expect = 0.060
Identities = 65/269 (24%), Positives = 87/269 (32%), Gaps = 72/269 (26%)
Query: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELS-APRGTNQTCHPGCHCP-----SGMLLLNNV 3135
C G P CP D+ L+ +GP C L+ G TCH H P G +L +V
Sbjct: 1857 CRGSCP-TCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCH--AHVPPESFFKGCVL--DV 1909
Query: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
C+ D C ++ +A C + W C
Sbjct: 1910 CMGGGDRDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 1946
Query: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
+C P H + P++ PS P P T +C GP E C + DR
Sbjct: 1947 EITC-PENSHYEVCGSPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 2000
Query: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
G G W ++ CS+ C G + C P GLG
Sbjct: 2001 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 2051
Query: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
EVC LP C + AE G P
Sbjct: 2052 --EVCGLLPSGQHGCQPVSTAECQAWGDP 2078
Score = 40.0 bits (92), Expect = 0.060
Identities = 60/231 (25%), Positives = 79/231 (34%), Gaps = 52/231 (22%)
Query: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 4634 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 4684
Query: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
+ + PGGL CP A C +G + + P CP
Sbjct: 4685 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLGEWRRPDFCP 4736
Query: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
L C S C P P GC C G VL + CV QC CL
Sbjct: 4737 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 4795
Query: 1872 VDGARY------WPGQRIKADCQL-----CICQDGRPRRCRLNPDCAVDCG 1911
DG Y +PG + C+ CQ+G C + +C ++ G
Sbjct: 4796 HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG--AACGPHEECRLEDG 4844
Score = 40.0 bits (92), Expect = 0.060
Identities = 29/100 (29%), Positives = 34/100 (34%), Gaps = 10/100 (10%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C + C C G CA C C GC C L G CIP ++C C H
Sbjct: 5121 CPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDCGCTH 5178
Query: 4483 TSA-AGAGMTLAPGDRLQLGCKE-CECRRGE-LHCTSQGC 4519
+L D C E C C L C + GC
Sbjct: 5179 NGRYLPVNSSLLTSD-----CSERCSCSSSSGLTCQAAGC 5213
Score = 39.7 bits (91), Expect = 0.078
Identities = 62/249 (24%), Positives = 83/249 (33%), Gaps = 46/249 (18%)
Query: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
G + PS G G+W W P W C +C + R + C PL
Sbjct: 1831 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA------- 1882
Query: 1733 PGPEHQSQACFTAACPVDGEWSTWSPWSVCS-EPCRGTMTRQRQCHSPQNGGRTCAALPG 1791
PG C P S + C + C G R C + + C A
Sbjct: 1883 PGTGGPFTTCHAHVPPE-------SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGV 1935
Query: 1792 GLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVTCPP--DWPCGSPGC 1848
+ R Q GC TC ++ C +PCP +C +T P + PC GC
Sbjct: 1936 VIEDWRA-----QVGC-EITCPENSHYEVCGSPCPASCPS-PAPLTTPAVCEGPCVE-GC 1987
Query: 1849 WCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------RPRR 1899
C G VL ++ C C +G + G AD Q C C G P
Sbjct: 1988 QCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2047
Query: 1900 CRLNPDCAV 1908
C L C +
Sbjct: 2048 CGLGEVCGL 2056
Score = 39.7 bits (91), Expect = 0.078
Identities = 62/253 (24%), Positives = 81/253 (32%), Gaps = 54/253 (21%)
Query: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
G + PS G G+W W P W C +C + R + C PL
Sbjct: 4233 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLS----SGT 4287
Query: 1733 PGP-----EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCA 1787
GP H F C +D C G R C + + C
Sbjct: 4288 GGPFTTCHAHVPPESFFKGCVLD--------------VCMGGGDRDILCKALASYVAACQ 4333
Query: 1788 ALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCG 1844
A + R Q GC TC ++ C P CP +C +T P + PC
Sbjct: 4334 AAGVVIEDWRA-----QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCV 4386
Query: 1845 SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------ 1895
GC C G VL ++ C C +G + G AD Q C C G
Sbjct: 4387 E-GCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 4445
Query: 1896 RPRRCRLNPDCAV 1908
P C L C +
Sbjct: 4446 TPASCGLGEVCGL 4458
Score = 39.3 bits (90), Expect = 0.10
Identities = 62/249 (24%), Positives = 82/249 (32%), Gaps = 46/249 (18%)
Query: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
G + PS G G+W W P W C +C + R + C PL
Sbjct: 3032 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA------- 3083
Query: 1733 PGPEHQSQACFTAACPVDGEWSTWSPWSVCS-EPCRGTMTRQRQCHSPQNGGRTCAALPG 1791
PG C P S + C + C G R C + + C A
Sbjct: 3084 PGTGGPFTTCHAHVPPE-------SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGV 3136
Query: 1792 GLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCGSPGC 1848
+ R Q GC TC ++ C P CP +C +T P + PC GC
Sbjct: 3137 VIEDWRA-----QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCVE-GC 3188
Query: 1849 WCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------RPRR 1899
C G VL ++ C C +G + G AD Q C C G P
Sbjct: 3189 QCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 3248
Query: 1900 CRLNPDCAV 1908
C L C +
Sbjct: 3249 CGLGEVCGL 3257
Score = 39.3 bits (90), Expect = 0.10
Identities = 65/269 (24%), Positives = 86/269 (31%), Gaps = 72/269 (26%)
Query: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELS-APRGTNQTCHPGCHCP-----SGMLLLNNV 3135
C G P CP D+ L+ +GP C L+ G TCH H P G +L +V
Sbjct: 3058 CRGSCP-TCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCH--AHVPPESFFKGCVL--DV 3110
Query: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
C+ D C ++ +A C + W C
Sbjct: 3111 CMGGGDRDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 3147
Query: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
+C P H P++ PS P P T +C GP E C + DR
Sbjct: 3148 EITC-PENSHYEVCGPPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 3201
Query: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
G G W ++ CS+ C G + C P GLG
Sbjct: 3202 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 3252
Query: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
EVC LP C + AE G P
Sbjct: 3253 --EVCGLLPSGQHGCQPVSTAECQAWGDP 3279
Score = 38.9 bits (89), Expect = 0.13
Identities = 31/101 (30%), Positives = 35/101 (34%), Gaps = 8/101 (7%)
Query: 4940 CEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
C C L C S GCVC G F C+P C C H G H PG
Sbjct: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQT 1203
Query: 4999 WQ--EACES-CLCLSGRPVCTQHCSPLTCAQGEEMVLEPGS 5036
+ C+S C C G V C +C E GS
Sbjct: 1204 FYPGPGCDSLCHCQEGGLV---SCESSSCGPHEACQPSGGS 1241
Score = 37.4 bits (85), Expect = 0.39
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 27/124 (21%)
Query: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
GP+ C E R +C C ++ C T C+ AG
Sbjct: 5058 GPFATCQAVLSPSEYFR--QCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS 5115
Query: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQ 3749
CPA Y C C SCA ++ GC + C EGC C + + C VQ
Sbjct: 5116 FCPLHCPAHSHYSICT--RTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQ 5172
Query: 3750 ECPC 3753
+C C
Sbjct: 5173 DCGC 5176
Score = 35.8 bits (81), Expect = 1.1
Identities = 63/242 (26%), Positives = 79/242 (32%), Gaps = 58/242 (23%)
Query: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 2232 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 2282
Query: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
+ + PGGL CP A C +G + + P CP
Sbjct: 2283 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLREWRRPDFCP 2334
Query: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
C S C P P GC C G VL + CV QC CL
Sbjct: 2335 FQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 2393
Query: 1872 VD------GARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPC 1925
D G ++PG + LC C++G V C SS P C
Sbjct: 2394 HDDRYYPLGQTFYPGPGCDS---LCRCREGG----------EVSCEPSSCGPHETCRPSG 2440
Query: 1926 GS 1927
GS
Sbjct: 2441 GS 2442
Score = 35.8 bits (81), Expect = 1.1
Identities = 63/242 (26%), Positives = 79/242 (32%), Gaps = 58/242 (23%)
Query: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 3433 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 3483
Query: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
+ + PGGL CP A C +G + + P CP
Sbjct: 3484 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLREWRRPDFCP 3535
Query: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
C S C P P GC C G VL + CV QC CL
Sbjct: 3536 FQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 3594
Query: 1872 VD------GARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPC 1925
D G ++PG + LC C++G V C SS P C
Sbjct: 3595 HDDRYYPLGQTFYPGPGCDS---LCRCREGG----------EVSCEPSSCGPHETCRPSG 3641
Query: 1926 GS 1927
GS
Sbjct: 3642 GS 3643
Score = 34.7 bits (78), Expect = 2.5
Identities = 36/150 (24%), Positives = 46/150 (30%), Gaps = 33/150 (22%)
Query: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPC---------------DMCLGQS 3491
R +CP TCP D G GP GP++ C D+C+G
Sbjct: 1858 RGSCP---TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 1914
Query: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
R C + G + Q C CG PCP SC +P
Sbjct: 1915 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGSPCPASCPSPAP 1972
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
+ C C C G + CVP
Sbjct: 1973 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 2002
Score = 34.3 bits (77), Expect = 3.3
Identities = 36/150 (24%), Positives = 46/150 (30%), Gaps = 33/150 (22%)
Query: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPC---------------DMCLGQS 3491
R +CP TCP D G GP GP++ C D+C+G
Sbjct: 3059 RGSCP---TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 3115
Query: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
R C + G + Q C CG PCP SC +P
Sbjct: 3116 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGPPCPASCPSPAP 3173
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
+ C C C G + CVP
Sbjct: 3174 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 3203
Score = 34.3 bits (77), Expect = 3.3
Identities = 36/150 (24%), Positives = 46/150 (30%), Gaps = 33/150 (22%)
Query: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPC---------------DMCLGQS 3491
R +CP TCP D G GP GP++ C D+C+G
Sbjct: 4260 RGSCP---TCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 4316
Query: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
R C + G + Q C CG PCP SC +P
Sbjct: 4317 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGPPCPASCPSPAP 4374
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
+ C C C G + CVP
Sbjct: 4375 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 4404
Score = 32.7 bits (73), Expect = 9.6
Identities = 25/63 (39%), Positives = 26/63 (41%), Gaps = 8/63 (12%)
Query: 3690 QVCREAGCPAGRLYRECQPGEGCPFSC---AHVTQQVGCFSEG-CEEGCHCPEGTFQHRL 3745
QV E CP Y C G CP SC A +T C EG C EGC C G
Sbjct: 1943 QVGCEITCPENSHYEVC--GSPCPASCPSPAPLTTPAVC--EGPCVEGCQCDAGFVLSAD 1998
Query: 3746 ACV 3748
CV
Sbjct: 1999 RCV 2001
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 357 bits (916), Expect = 2e-97
Identities = 330/1237 (26%), Positives = 464/1237 (37%), Gaps = 183/1237 (14%)
Query: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH-LTP--------GDRCPQPG 243
ATC W HY +FDGR + F G C Y+LA + LTP P
Sbjct: 73 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVS 132
Query: 244 HCQRVTMGPEEVLI-----QAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
+ + VT+ I + G V V G L S +S+ +L G+
Sbjct: 133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 192
Query: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
V D + +++ G GLCG + P +D + P G LA +G SWR PG +
Sbjct: 193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 252
Query: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
C D + P ++ PG A GPF CHA V P + + C
Sbjct: 253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT-----GGPFTTCHAHVPPESFFKGC 307
Query: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSD 477
+ C G G +C ASYV AC + I WR CE CP Y
Sbjct: 308 VLDVCMGG-------GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 360
Query: 478 CVSLCPPSCEAVGQGEEES-CREECVSGCECPRGLFWNGTLCVPAAH-CPCY-------- 527
C CP SC + + C CV GC+C G + CVP + C C+
Sbjct: 361 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 420
Query: 528 --------YCRQ--RYVPGDTVRQLCNPCVCRDGR--------WHCAQALCPAECAVGGD 569
C Q R PG +C P C G H Q + AEC GD
Sbjct: 421 GSEFWADGTCSQWCRCGPGGG-SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 479
Query: 570 GHYLTFDGRSYSFWGGQGCRYSL----------VQDYVKGQLLILLEHGACDAGSCLHAI 619
HY+T DG + F G C Y L +++ + + EH A S ++
Sbjct: 480 PHYVTLDGHRFDFQG--TCEYLLSAPCHGPPLGAENFT---VTVANEHRGSQAVSYTRSV 534
Query: 620 SVSLEDTHIQL--RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
++ + + + L R + V+G V LP+ + L S A +++ L
Sbjct: 535 TLQIYNHSLTLSARWPRKLQVDGVFVALPF-QLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
Query: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGK---GRC 734
D + + +A + GLCG + Q+ DD G + +QV G G C
Sbjct: 594 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 645
Query: 735 PSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAVCGCDP 792
S+ SPCT Q AC ++ ++ CH LV ++ CL C
Sbjct: 646 VSKPCP--SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG 703
Query: 793 GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPE 848
LCP ++ Y C GA WR CP+ CP Y C +C C PE
Sbjct: 704 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE 763
Query: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERG 908
C +C GC C G + + CVP C C R Y G
Sbjct: 764 GCE--SACREGCVCDAGFVLSGD-TCVPVGQCGCLHDGRYYPLGE--------------- 805
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
V+ PG P C G C G C
Sbjct: 806 -------------------VFYPG--------PECERRCECGPGGHVTCQEGAA-----C 833
Query: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
P + C +++ C H TG GRC A+G HY+T DG
Sbjct: 834 GPHEEC-------------RLEDGVQAC-------HATG---CGRCLANGGIHYITLDGR 870
Query: 1029 AFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVN 1088
+ G+C Y+L + ++ + + L V + G VV + +G+ VTV+
Sbjct: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 930
Query: 1089 GVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGD 1148
G +V P V G + + G ++L T GL LL+DG +L+ + FRGR+ GLCG+
Sbjct: 931 GEAVALP-VAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGN 988
Query: 1149 FDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP-GDLPHPCTMNTHRAGW-ARA 1203
F+G+ S+D G + E +WR+ S C E G P + A + +
Sbjct: 989 FNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNE 1048
Query: 1204 RCGALLQPL--FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGH 1261
CG L P F C A + P +++ C+YD C GD LC ++A Y C G
Sbjct: 1049 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGV 1106
Query: 1262 HVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLL 1320
V+ WR+ C L C Y C TC +C G C EGC C + LL
Sbjct: 1107 AVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLL 1163
Query: 1321 HGGACLEPASCPCEWGRNSFP-PGSVLQKDCG-NCTC 1355
G C+ C C P S+L DC C+C
Sbjct: 1164 SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC 1200
Score = 246 bits (628), Expect = 4e-64
Identities = 299/1223 (24%), Positives = 426/1223 (34%), Gaps = 247/1223 (20%)
Query: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
D +++G + P + + P P CP P T PA P G C
Sbjct: 341 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 393
Query: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 394 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 437
Query: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 438 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 494
Query: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 495 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 554
Query: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 555 VDGVFVALPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 606
Query: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV----------- 365
GLCG YN P DD GG A W++ G++ GC + V
Sbjct: 607 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGECVSKPCPSPCTPE 657
Query: 366 --EVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
E G D G+I A +GP CH V PA+Y + CL C
Sbjct: 658 QQESFGGPDACGVISA------------------TDGPLAPCHGLVPPAQYFQGCLLDAC 699
Query: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYSDCVSLC 482
+G +C A+YV AC + WR+P FC CP Y C C
Sbjct: 700 Q-------VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
Query: 483 PPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPG 536
P SC ++ E C C GC C G +G CVP C C Y + + PG
Sbjct: 753 PVSCPSL--SAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 810
Query: 537 DTVRQLC-------------------NPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDG 577
+ C C DG C C C G HY+T DG
Sbjct: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDG 869
Query: 578 RSYSFWGGQGCRYSLVQ----DYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDS 633
R Y G C Y L Q I+LE A AG L + V++ + L
Sbjct: 870 RVYDLHG--SCSYVLAQVCHPKPGDEDFSIVLEKNA--AGD-LQRLLVTVAGQVVSLAQG 924
Query: 634 GAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQV 693
V V+G+ V LP + + V +L G ++L+ D +++ ++
Sbjct: 925 QQVTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFD-GDAHLLMSIPSPFRGRL 982
Query: 694 QGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL--LSPCTTHSQR 751
GLCG F N DDF+ P G +S+ F + ++V G + E C
Sbjct: 983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETA 1042
Query: 752 HAFAEAACAILHS--SVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCA 809
+ AC L + F C ++ ++ +C+ +C LC L+AY C
Sbjct: 1043 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 1102
Query: 810 QEG-ASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPED-CGELGSCVAGCNCPLGLL 867
G A PWR + CP+ CP Y C C C G C GC C L
Sbjct: 1103 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFL 1162
Query: 868 WDPEGQCVPPSLCPCQLGARRYAPGSATM--KECN-RCICQERGLWNCTARHCPSQAFC- 923
+G C+P C C RY P ++++ +C+ RC C C A CP C
Sbjct: 1163 LS-QGVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE 1220
Query: 924 ----PRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHS 979
R G C+L S AN + G+ G PG L RC P L +++
Sbjct: 1221 VKAEARNCWATRGLCVL---SVGANLTTFDGAR-GATTSPGVYELSSRC--PGL---QNT 1271
Query: 980 GQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYL 1039
WY A +Q +C G+ +A G H DG+ P
Sbjct: 1272 IPWYRVVAEVQ------ICH------------GKTEAVGQVHIFFQDGMVTLTP------ 1307
Query: 1040 LVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYT 1099
+ V VNG+ V P
Sbjct: 1308 ------------------------------------------NKGVWVNGLRVDLPAEKL 1325
Query: 1100 GPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRS 1159
R LL+ G+ + +V V +S G++ G CG+FDGD +ND
Sbjct: 1326 ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHD 1385
Query: 1160 RQGVLEPTAELAAHSWRLSPLCP 1182
Q + A WR P
Sbjct: 1386 SQ------EKPAMEKWRAQDFSP 1402
Score = 186 bits (472), Expect = 5e-46
Identities = 150/526 (28%), Positives = 215/526 (40%), Gaps = 78/526 (14%)
Query: 934 CLLTCDSPSANHS---CPAGSTDGCVCPPGTVLLDERCVPPDL-CPC------RHSGQWY 983
C +C SP+ + C +GC C G VL +RCVP + C C +G +
Sbjct: 365 CPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEF 424
Query: 984 LPNATIQEDCNVCVCRGRQWHCT---------------GQR-----RSGRCQASGAPHYV 1023
+ T + C C G CT GQ + CQA G PHYV
Sbjct: 425 WADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 483
Query: 1024 TFDGLAFTYPGACEYLLVREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGT 1075
T DG F + G CEYLL G FTV+ N G+ ++ T+++ +++
Sbjct: 484 TLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSL 543
Query: 1076 VVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLS 1135
+ R + V+GV V P L +G ++++T GL+L +DG + V +++
Sbjct: 544 TLSARWPRKLQVDGVFVALP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVP 602
Query: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNT 1195
+ + GLCG+++ D ++DL++ G +P + +P P PCT
Sbjct: 603 AAYAASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQ 658
Query: 1196 HRAGWARARCGALLQ---PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATY 1252
+ CG + PL CH VPP Q+++ CL DAC G LC A+ATY
Sbjct: 659 QESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATY 715
Query: 1253 ADECARHGHHV-RWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEG 1311
C G + WR + C LQC YE CG +CP +C G C+ AC EG
Sbjct: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG--CE-SACREG 772
Query: 1312 CFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEE 1371
C C G +L G C+ C C +P G V G CE
Sbjct: 773 CVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFY-----------------PGPECER 815
Query: 1372 LVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417
G CQE C PH ++C + C A GCG
Sbjct: 816 RCECGPGGHVTCQEGAACGPH-------EECRLEDGVQACHATGCG 854
Score = 164 bits (414), Expect = 3e-39
Identities = 130/420 (30%), Positives = 177/420 (42%), Gaps = 40/420 (9%)
Query: 991 EDCNVCVCRGRQWHCTGQRRSGRCQAS--------GAPHYVTFDGLAFTYPGACEYLLVR 1042
+ C+ CR ++ C Q G C + G PHY +FDG F + G C Y+L
Sbjct: 45 DPCHGVTCRPQET-CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 103
Query: 1043 ------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRA--VTVNGVSV 1092
GL FTV+ +N G ++ + + V GT + + + V VNGV
Sbjct: 104 TGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 163
Query: 1093 TPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGD 1152
P +S+ + LL GL + +D RV V L + G V GLCG+ D +
Sbjct: 164 ALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 223
Query: 1153 ASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPCTMNTHRAGWARARCGA 1207
+ND G L P+ + SWR PLC + G P C + CG
Sbjct: 224 PNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TCPEDRLEQYEGPGFCGP 282
Query: 1208 LLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR 1264
L FT CHA VPP+ ++ C+ D C GGD + LC A+A+Y C G +
Sbjct: 283 LAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGVVIE 340
Query: 1265 -WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGG 1323
WR+Q C + C YE CGP CP +C P CVEGC C G +L
Sbjct: 341 DWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSAD 400
Query: 1324 ACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGGDGGHCEELVPACAEGE 1380
C+ C C W ++ GS D G C+ QW CG GG +C GE
Sbjct: 401 RCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGPGGGSLVCTPASCGLGE 454
Score = 69.7 bits (169), Expect = 7e-11
Identities = 41/123 (33%), Positives = 48/123 (39%), Gaps = 13/123 (10%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 736 PLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 795
Query: 3146 HEGHLYPPGSTVV--RPCE-NCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
H+G YP G CE C C G C EG + P +C G
Sbjct: 796 HDGRYYPLGEVFYPGPECERRCECGPG-----GHVTCQEG----AACGPHEECRLEDGVQ 846
Query: 3203 RCH 3205
CH
Sbjct: 847 ACH 849
Score = 67.0 bits (162), Expect = 5e-10
Identities = 35/99 (35%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C + SCA LS G C GC C LL VC+P QDC C
Sbjct: 1118 PLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCT 1177
Query: 3146 HEGHLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEG 3182
H G P S+++ E CSC S C + C G
Sbjct: 1178 HNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
Score = 63.5 bits (153), Expect = 5e-09
Identities = 65/212 (30%), Positives = 77/212 (36%), Gaps = 56/212 (26%)
Query: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP------PPKNGG------APCPGASQ 2599
G+W W+ W C SC + R P P GG A P S
Sbjct: 244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 303
Query: 2600 ERAPCGLQPCSGGTD----CELGRVYVSADLCQKGLV----------------------- 2632
+ C L C GG D C+ YV+A CQ V
Sbjct: 304 FKG-CVLDVCMGGGDHDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEV 360
Query: 2633 --PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWP 2686
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C
Sbjct: 361 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 420
Query: 2687 GVSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
G F G CSQ C C G L+C P C L
Sbjct: 421 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
Score = 60.1 bits (144), Expect = 6e-08
Identities = 65/227 (28%), Positives = 83/227 (36%), Gaps = 40/227 (17%)
Query: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 248 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLAPGTGGPFTTCHAHVPP 300
Query: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
C GG C +LA C D Q C CPEN +
Sbjct: 301 ESFFKGCVLDVCMGG-GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 358
Query: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 359 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 413
Query: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 414 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 460
Score = 55.8 bits (133), Expect = 1e-06
Identities = 66/241 (27%), Positives = 81/241 (33%), Gaps = 44/241 (18%)
Query: 3177 WPCAEGEPTWSPWTPWSQCSASCGPA---RCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
W + P W P W +C SC R ++ P T P P
Sbjct: 242 WGGSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP- 299
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
PE+ + C+L C G C L S AC Q G E
Sbjct: 300 ---PESFFKGCVLDVCMGGGDHDIL-----CK-----ALASYVAAC-----QAAGVVIED 341
Query: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH------CVWRCQPGCYCP 3347
RAQ V + CP E + Y CGPPCP SC C C GC C
Sbjct: 342 WRAQ--VGCEITCP-------ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
Query: 3348 PGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CTCLE--GRLNCTDLP 3404
G VLS++ + + G C C G H G+ C+ C C G L CT
Sbjct: 393 AGFVLSADRCVPLNNG-CGC--WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 449
Query: 3405 C 3405
C
Sbjct: 450 C 450
Score = 55.1 bits (131), Expect = 2e-06
Identities = 65/257 (25%), Positives = 90/257 (35%), Gaps = 33/257 (12%)
Query: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 212 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 268
Query: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLR 4027
RL Y PG G P F A P + + C GG +
Sbjct: 269 DRLEQYEGPGFCGPLAPG-----TGGPFTTCHAHVPPESFFKGCVLDVC--MGGGDHDIL 321
Query: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC---SDLQE 4084
++ +S + A E +A+ + CE CP C CP C + L
Sbjct: 322 CKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSPAPLTT 377
Query: 4085 GIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQHQDAC 4137
VC+ C +GC+C G + CVP+ + C C +A WA G+ Q
Sbjct: 378 PAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWC- 434
Query: 4138 NNCSCQAGQLSCTAQPC 4154
C G L CT C
Sbjct: 435 -RCGPGGGSLVCTPASC 450
Score = 54.7 bits (130), Expect = 2e-06
Identities = 68/233 (29%), Positives = 81/233 (34%), Gaps = 57/233 (24%)
Query: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
C S PC SP TP Q S GP C + +T PL P
Sbjct: 645 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 683
Query: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
P + CLL C G G P + + AC Q LG++
Sbjct: 684 LVPPAQYFQGCLLDACQVQGHPGGLCP----------AVATYVAACQAAGAQ-LGEW--- 729
Query: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQ 3350
+ + C L CP + Y CG CP SC L C C+ GC C G
Sbjct: 730 --RRPDFCP-LQCPAHS-------HYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGF 779
Query: 3351 VLSSNGAICVQPGHCSCLD----LLTGQRHHPGARLARPDGC---NHCTCLEG 3396
VLS G CV G C CL G+ +PG R C H TC EG
Sbjct: 780 VLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 830
Score = 54.3 bits (129), Expect = 3e-06
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 9/126 (7%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C C C+ L C C +GC C L G C+P+ C
Sbjct: 1117 CPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDC 1174
Query: 4118 DCTDAQGHSWAPGSQHQDACN-NCSCQAGQ-LSCTAQPCPPPTHC-----AWSHWSAWSP 4170
CT + S C+ CSC + L+C A CPP C A + W+
Sbjct: 1175 GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL 1234
Query: 4171 CSHSCG 4176
C S G
Sbjct: 1235 CVLSVG 1240
Score = 53.9 bits (128), Expect = 4e-06
Identities = 61/243 (25%), Positives = 80/243 (32%), Gaps = 33/243 (13%)
Query: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 626 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 685
Query: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
P Q +G C ++A C +Q + C QCP + +
Sbjct: 686 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHY 745
Query: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
E C G CP C + C C GC C G L +C+P QC C G+
Sbjct: 746 ---ELC---GDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 799
Query: 2953 LYASGAM-------ARLDSC---NNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCN 3002
Y G + R C + TC G E C + G C N
Sbjct: 800 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 859
Query: 3003 VGI 3005
GI
Sbjct: 860 GGI 862
Score = 53.5 bits (127), Expect = 5e-06
Identities = 59/224 (26%), Positives = 77/224 (34%), Gaps = 40/224 (17%)
Query: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 632 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 688
Query: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
G + +G PG VA CQA + + CP +CP C
Sbjct: 689 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC 748
Query: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 749 GDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPL---- 803
Query: 4888 EEQAQELPPGTVLTRNCT-----RCVCHGGAFSCSLVDCQVPPG 4926
+ PG R C C GA +C++ G
Sbjct: 804 ---GEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
Score = 52.8 bits (125), Expect = 9e-06
Identities = 58/233 (24%), Positives = 75/233 (32%), Gaps = 55/233 (23%)
Query: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 652 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 701
Query: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
G P CP T CQ Q + C CG CP SC LS
Sbjct: 702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 761
Query: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
C+ C+ C C G + CVP C C + G +
Sbjct: 762 PEGCESA---CREGCVCDAGFVLSGDTCVPVGQCGCLHD--------------GRYYPLG 804
Query: 3612 ESLEPGEVVTGPCD-NCTC-VAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCG 3662
E PG C+ C C G + CQE C GP E+C + G
Sbjct: 805 EVFYPGP----ECERRCECGPGGHVTCQEGAAC---------GPHEECRLEDG 844
Score = 52.8 bits (125), Expect = 9e-06
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
C SC C+ C EGC C LL C+P+ +C C S L +
Sbjct: 1134 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 1193
Query: 2695 CSQ-CVCEKGE-LLCQPGGCP 2713
CS+ C C L CQ GCP
Sbjct: 1194 CSERCSCSSSSGLTCQAAGCP 1214
Score = 51.6 bits (122), Expect = 2e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 792
Query: 4118 DCTD-----AQGHSWAPGSQHQDACNNCSC-QAGQLSC-TAQPCPPPTHC 4160
C G + PG + + C C G ++C C P C
Sbjct: 793 GCLHDGRYYPLGEVFYPGPECE---RRCECGPGGHVTCQEGAACGPHEEC 839
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 365 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 423
Query: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
W + S C G + C+P +C GE L P C P E P
Sbjct: 424 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 483
Query: 5055 LLTELRNFTKGTC 5067
L R +GTC
Sbjct: 484 TLDGHRFDFQGTC 496
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CP SC A C C EGC C G +L C+P+ +C CL G F G
Sbjct: 752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 811
Query: 2695 CSQCVCEKGELLCQPGG 2711
+ CE C PGG
Sbjct: 812 ECERRCE-----CGPGG 823
Score = 47.4 bits (111), Expect = 4e-04
Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 9/130 (6%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
C SLA C + T C CP + + + Q G C L G
Sbjct: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ--GSCAALSGLTG-- 1146
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ-LYASGAMARLDSCNNCTCVSGK 2974
CT C GC C L C+P C C +G+ L + ++ D C+C S
Sbjct: 1147 --CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 1204
Query: 2975 -MACTSERCP 2983
+ C + CP
Sbjct: 1205 GLTCQAAGCP 1214
Score = 47.0 bits (110), Expect = 5e-04
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 13/126 (10%)
Query: 4642 AEALCGGGCREPWAQESCNGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPC 4700
A G +PW +S CP C A C C SCA L C C
Sbjct: 1099 AACQAAGVAVKPWRTDSF----CPLHCPAHSHYSI--CTRTCQGSCAALSGLTGCTTR-C 1151
Query: 4701 RPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDC-QNCTCVNES-LVC 4758
GC C L+ G C+P+ C C + N + + + DC + C+C + S L C
Sbjct: 1152 FEGCECDDRFLLSQGVCIPVQDCGC---THNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 1208
Query: 4759 PHQECP 4764
CP
Sbjct: 1209 QAAGCP 1214
Score = 46.6 bits (109), Expect = 6e-04
Identities = 49/194 (25%), Positives = 65/194 (33%), Gaps = 31/194 (15%)
Query: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
A CQA + CP CP S C +C C L C C GC C
Sbjct: 1099 AACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCEC 1157
Query: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELP-PGTVLTRNCT-RCVCHGGA 4913
LL G C+P C CT + + LP ++LT +C+ RC C +
Sbjct: 1158 DDRFLLSQGVCIPVQDCGCTHN-------------GRYLPVNSSLLTSDCSERCSCSSSS 1204
Query: 4914 -FSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFR 4972
+C C PPG +CE N T+ C + + G
Sbjct: 1205 GLTCQAAGC--PPGR-----------VCEVKAEARNCWATRGLCVLSVGANLTTFDGARG 1251
Query: 4973 SQAGPCVPEDHCEC 4986
+ P V E C
Sbjct: 1252 ATTSPGVYELSSRC 1265
Score = 45.8 bits (107), Expect = 0.001
Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
C +C ++A + C SA GCVC G F CVP C C H LG
Sbjct: 752 CPVSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
Query: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG 5035
PG E + CE C G V Q + C EE LE G
Sbjct: 808 YPGPECERRCE---CGPGGHVTCQEGA--ACGPHEECRLEDG 844
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 349 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 406
Query: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
C CW + + AG C+ C G L CT C GLLP
Sbjct: 407 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 460
Score = 45.1 bits (105), Expect = 0.002
Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 24/152 (15%)
Query: 4796 VAPCQA-----QDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQP---GAICVQE 4847
VA CQA +D + C + CP C CP C P A+C +
Sbjct: 329 VAACQAAGVVIEDWRAQVGCEIT----CPENSHYEVCGPPCPASCPSPAPLTTPAVC-EG 383
Query: 4848 PCQPGCGCPGGQLLHNGTCVP-PTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTR 4906
PC GC C G +L CVP C C + T E E ++ C R
Sbjct: 384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANG-------TYHEAGSEFWADGTCSQWC-R 435
Query: 4907 CVCHGGAFSCSLVDCQVPPGETWQQVAPGELG 4938
C GG+ C+ C + GE + G+ G
Sbjct: 436 CGPGGGSLVCTPASCGL--GEVCGLLPSGQHG 465
Score = 45.1 bits (105), Expect = 0.002
Identities = 51/222 (22%), Positives = 68/222 (30%), Gaps = 73/222 (32%)
Query: 4357 CYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAG-----APCTRL---DG 4408
C S PCP C +Q+ GP + G + APC L
Sbjct: 645 CVSKPCPSPCT---------------PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 689
Query: 4409 HFRPCLISNCS----EDSCTPPFEFHACGSPCAGL--------------CATHLSHQLCQ 4450
+F+ CL+ C P + AG C H ++LC
Sbjct: 690 YFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCG 749
Query: 4451 DLPP---------------CQPGCYCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAP 4494
D P C+ GC C G + C+P +C C H G P
Sbjct: 750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYP 809
Query: 4495 GDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGP 4536
G + + CEC G H T Q E + CGP
Sbjct: 810 GPECE---RRCECGPGG-HVTCQ------------EGAACGP 835
Score = 44.7 bits (104), Expect = 0.002
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 14/96 (14%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC-----GLPSANA 4732
C + CP SC L C + CR GC C G ++ CVP+ C C P
Sbjct: 748 CGDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 806
Query: 4733 SWELAPAQAVQLDCQ-----NCTCVNESLVCPHQEC 4763
+ P + C+ + TC + PH+EC
Sbjct: 807 FY---PGPECERRCECGPGGHVTCQEGAACGPHEEC 839
Score = 44.3 bits (103), Expect = 0.003
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 340 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 392
Query: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 393 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 449
Query: 4763 C 4763
C
Sbjct: 450 C 450
Score = 43.9 bits (102), Expect = 0.004
Identities = 148/650 (22%), Positives = 200/650 (30%), Gaps = 152/650 (23%)
Query: 3078 GLQPC----AGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH---PGCHCPSGML 3130
G Q C + P P C ++Q + GP +C +SA G CH P G L
Sbjct: 638 GAQGCGECVSKPCPSPCTPEQQ--ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 695
Query: 3131 LLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWT 3190
L C +GH PG C V+ +A C + GE W
Sbjct: 696 L----------DACQVQGH---PGGL-------CPAVATYVAACQAAGAQLGE-----WR 730
Query: 3191 PWSQCSASCGPARCHRHRFCARS-PSAVPSTVAPLPLPATPTPLC---SGPEAEEEPCLL 3246
C C PA H + C S P + PS AP + C +G + C+
Sbjct: 731 RPDFCPLQC-PAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVP 788
Query: 3247 QG---CDRAGGWGPWG----PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC---EGPRA 3296
G C G + P G P C R C G C + G + C +G +A
Sbjct: 789 VGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHV-TCQEGAACGPHEECRLEDGVQA 847
Query: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQ-----V 3351
C A C C A G Y R D C + C+ PG V
Sbjct: 848 ----CHATGCG--RCLANGGIHYITLDG---RVYDLHGSCSYVLAQVCHPKPGDEDFSIV 898
Query: 3352 LSSNGAICVQPGHCSC----LDLLTGQRHH-PGARLARPDGCNHC-TCLEGR---LNCT- 3401
L N A +Q + + L GQ+ G +A P EGR L T
Sbjct: 899 LEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK 958
Query: 3402 --------------DLPCPVPGGWCP--------WSE-WTMCSQPCRGQTRSRSRACACP 3438
+P P G C WS+ + + + + A P
Sbjct: 959 GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVP 1018
Query: 3439 TPQHGGAPCTGEAG-------EAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQS 3491
G G G E EAC P GP++ C L S
Sbjct: 1019 GSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN--------PQGPFATCQAVLSPS 1070
Query: 3492 HRSRACSRPPTPEGG-------------RPCPGNHTQSRPCQENSTQCTDCGGGQSLHPC 3538
R C + G C +P + +S C C
Sbjct: 1071 EYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSIC 1130
Query: 3539 GQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPE 3598
+ C SC LS + C + C C C L G+C+P C C + +P
Sbjct: 1131 TRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTH--NGRYLPV 1185
Query: 3599 NQSRSAGSRFSSWESLEPGEVVTGPC-DNCTCVAGI-LQCQEVPDCPDPG 3646
N S ++T C + C+C + L CQ CP PG
Sbjct: 1186 NSS-----------------LLTSDCSERCSCSSSSGLTCQ-AAGCP-PG 1216
Score = 42.7 bits (99), Expect = 0.009
Identities = 58/252 (23%), Positives = 84/252 (33%), Gaps = 63/252 (25%)
Query: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 620 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 679
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
P G+ ++ C + C PG + C+ AG
Sbjct: 680 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLGEW 729
Query: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 730 RRPDFCPLQCPAHSHYELC--GDSCPVSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 786
Query: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSC---GNCSCAHGKL 3800
V C G PLG PG E + R C G+ +C G
Sbjct: 787 VPVGQC----------GCLHDGRYYPLGEVFYPGPECER----RCECGPGGHVTCQEGAA 832
Query: 3801 SCSLDDCFEADG 3812
++C DG
Sbjct: 833 CGPHEECRLEDG 844
Score = 41.6 bits (96), Expect = 0.021
Identities = 38/140 (27%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 4933 APGELGLCEQTCL-EMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGR 4991
A +C +TC A + C++ GC C SQ G C+P C C H GR
Sbjct: 1123 AHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ-GVCIPVQDCGCTHNGR 1181
Query: 4992 PHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSP 5051
+LP S L S C++ CS C+ + + C P
Sbjct: 1182 -YLP-------VNSSLLTSD---CSERCS---CSSSSGLTCQAAGCPP----------GR 1217
Query: 5052 SCQLLTELRN--FTKGTCYL 5069
C++ E RN T+G C L
Sbjct: 1218 VCEVKAEARNCWATRGLCVL 1237
Score = 41.2 bits (95), Expect = 0.027
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 411
Query: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
G + GS CS W C G S C PA
Sbjct: 412 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 449
Query: 3204 CHRHRFCARSPS 3215
C C PS
Sbjct: 450 CGLGEVCGLLPS 461
Score = 41.2 bits (95), Expect = 0.027
Identities = 34/111 (30%), Positives = 43/111 (38%), Gaps = 12/111 (10%)
Query: 3306 CPVTNCTAIEGAEYSPCGPPCPRSC---DDLVHCVWRCQPGCYCPPGQVLSSNGAICVQP 3362
CP+ +C A + YS C C SC L C RC GC C +LS +C+
Sbjct: 1117 CPL-HCPA--HSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVCIPV 1171
Query: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPGGWC 3412
C C G+ + L D C+C L C CP PG C
Sbjct: 1172 QDCGCTH--NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP-PGRVC 1219
Score = 40.0 bits (92), Expect = 0.060
Identities = 60/231 (25%), Positives = 79/231 (34%), Gaps = 52/231 (22%)
Query: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 634 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 684
Query: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
+ + PGGL CP A C +G + + P CP
Sbjct: 685 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLGEWRRPDFCP 736
Query: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
L C S C P P GC C G VL + CV QC CL
Sbjct: 737 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 795
Query: 1872 VDGARY------WPGQRIKADCQL-----CICQDGRPRRCRLNPDCAVDCG 1911
DG Y +PG + C+ CQ+G C + +C ++ G
Sbjct: 796 HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG--AACGPHEECRLEDG 844
Score = 40.0 bits (92), Expect = 0.060
Identities = 29/100 (29%), Positives = 34/100 (34%), Gaps = 10/100 (10%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C + C C G CA C C GC C L G CIP ++C C H
Sbjct: 1121 CPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDCGCTH 1178
Query: 4483 TSA-AGAGMTLAPGDRLQLGCKE-CECRRGE-LHCTSQGC 4519
+L D C E C C L C + GC
Sbjct: 1179 NGRYLPVNSSLLTSD-----CSERCSCSSSSGLTCQAAGC 1213
Score = 39.3 bits (90), Expect = 0.10
Identities = 65/269 (24%), Positives = 86/269 (31%), Gaps = 72/269 (26%)
Query: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELS-APRGTNQTCHPGCHCP-----SGMLLLNNV 3135
C G P CP D+ L+ +GP C L+ G TCH H P G +L +V
Sbjct: 259 CRGSCP-TCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCH--AHVPPESFFKGCVL--DV 311
Query: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
C+ D C ++ +A C + W C
Sbjct: 312 CMGGGDHDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 348
Query: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
+C P H P++ PS P P T +C GP E C + DR
Sbjct: 349 EITC-PENSHYEVCGPPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 402
Query: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
G G W ++ CS+ C G + C P GLG
Sbjct: 403 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 453
Query: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
EVC LP C + AE G P
Sbjct: 454 --EVCGLLPSGQHGCQPVSTAECQAWGDP 480
Score = 38.5 bits (88), Expect = 0.17
Identities = 34/117 (29%), Positives = 44/117 (37%), Gaps = 15/117 (12%)
Query: 1804 QDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCGSPGCWCPEGQVLGSEG 1860
Q GC TC ++ C P CP +C +T P + PC GC C G VL ++
Sbjct: 345 QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCVE-GCQCDAGFVLSADR 401
Query: 1861 WCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------RPRRCRLNPDCAV 1908
C C +G + G AD Q C C G P C L C +
Sbjct: 402 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGL 458
Score = 37.4 bits (85), Expect = 0.39
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 27/124 (21%)
Query: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
GP+ C E R +C C ++ C T C+ AG
Sbjct: 1058 GPFATCQAVLSPSEYFR--QCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS 1115
Query: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQ 3749
CPA Y C C SCA ++ GC + C EGC C + + C VQ
Sbjct: 1116 FCPLHCPAHSHYSICT--RTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQ 1172
Query: 3750 ECPC 3753
+C C
Sbjct: 1173 DCGC 1176
Score = 33.5 bits (75), Expect = 5.6
Identities = 36/148 (24%), Positives = 45/148 (30%), Gaps = 29/148 (19%)
Query: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPCDMCLGQSHRSRACSRPPTPEGG 3506
R +CP TCP D G GP GP++ C + + C GG
Sbjct: 260 RGSCP---TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 316
Query: 3507 RP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSPGS 3553
C + CQ D C CG PCP SC +P +
Sbjct: 317 DHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLT 376
Query: 3554 VCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
C C C G + CVP
Sbjct: 377 TPAVCEGPCVEGCQCDAGFVLSADRCVP 404
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 300 bits (767), Expect = 3e-80
Identities = 270/901 (29%), Positives = 362/901 (40%), Gaps = 138/901 (15%)
Query: 546 CVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL 605
C G+ C A A C GD HY TFDGR Y G C Y++V+ + L
Sbjct: 516 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMG--TCSYTMVELCSEDDTLPAF 572
Query: 606 ------EHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLVNGQDVGLPWIGAEG-LSVR 656
EH S + ++V + L + G VLV+ Q LP +EG L V
Sbjct: 573 SVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVY 632
Query: 657 RASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVE 716
++ ++ G V + +A ++L R QV GLCG + + DDFLTP G +
Sbjct: 633 QSGPRAVVELVFGLVVTYDWDCQLA-LSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 691
Query: 717 TSIAAFASKFQV-AGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILH--SSVFQECHRL 773
FAS +++ G C CT +H + C +L F CH
Sbjct: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
Query: 774 VDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQE 832
+D PF +C+ +C LC LSAYA+ C + G S WR+ CP+ CP
Sbjct: 752 LDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSR 811
Query: 833 YRECAPACGQHC---GKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
Y C PAC C P +C CV GC C G + G CVP S C C +
Sbjct: 812 YELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFV-ASGGACVPASSCGCTFQGLQL 869
Query: 890 APGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPA 949
APG + +CQ R CT Q C SCPA
Sbjct: 870 APGQEVWAD---ELCQRR----CTCNGATHQVTC------------------RDKQSCPA 904
Query: 950 GSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
G ERC ++Q C
Sbjct: 905 G---------------ERC-------------------SVQNGLLGCY----------PD 920
Query: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLV-----REASGLFTVSAQNLPCGASGLTC 1064
R G CQ SG PHYV+FDG F + G C YLLV A F V +N G+ ++
Sbjct: 921 RFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSY 980
Query: 1065 TKALAVRLEGTVVHMLR---GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLT 1121
T+A+ V G V + R G+ + + + P + G + + R G ++ T GLT
Sbjct: 981 TRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ-VQVFRQGRDAVVRTDFGLT 1039
Query: 1122 LLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--LSP 1179
+ +D RV ++ + + GLCG+F+GD ++DL R G A +SW+ P
Sbjct: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1099
Query: 1180 LC--PEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACG 1235
C EPGD P ++ + ++ CG L P F CH+++ PQ C+YD C
Sbjct: 1100 GCGATEPGDCPKLDSLVAQQL-QSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1158
Query: 1236 CDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE 1294
G LC A+ATYA C G V WRS+ELC L C YEAC CP +C +
Sbjct: 1159 LP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1216
Query: 1295 QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCT 1354
P PG C C EGC C EG L G +CL ASC C PPG
Sbjct: 1217 L-PVPG-GCG-SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFY------- 1266
Query: 1355 CQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
G C+ L C EG + E+ C PH + C GC A
Sbjct: 1267 ----------PGPGCDSLC-HCQEGGLVSCESSSCGPH-------EACQPSGGSLGCVAV 1308
Query: 1415 G 1415
G
Sbjct: 1309 G 1309
Score = 265 bits (677), Expect = 9e-70
Identities = 255/953 (26%), Positives = 363/953 (38%), Gaps = 178/953 (18%)
Query: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVT-M 250
+A C + HY TFDGR Y +G C+Y + + + + +RV+ +
Sbjct: 530 TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYV 589
Query: 251 GPEEVLIQAGNVSV-KGQ----LVPEGQSWLLHGLSLQWL-----GDWLVLSGGLGVVVR 300
G V + +VS+ +G+ LV +S L LS L G V+ G+VV
Sbjct: 590 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 649
Query: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
D +++S+ Q GLCG YNG P DDF+ P G LA A F +SW+L +
Sbjct: 650 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 709
Query: 361 CLDAVEVAQGCDPLGLIDADVEPGHLR-AEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
C D + C PG + E +C L L+GPF CH + P + E
Sbjct: 710 CEDGCQ--NNCPA-------CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 760
Query: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYS 476
C++ C G + ++C ++Y QAC I + WR P C CP Y
Sbjct: 761 CVYDLCVVG-------GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYE 813
Query: 477 DCVSLCPPSCEAVGQGEEESCR-EECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVP 535
C CP SC G +C CV GC C G +G CVPA+ C C + + P
Sbjct: 814 LCGPACPTSCN--GAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAP 871
Query: 536 GDTV--------RQLCN----PCVCRDGRWHCAQALCPAE-------------CAVGGDG 570
G V R CN CRD + A C + C GD
Sbjct: 872 GQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDP 931
Query: 571 HYLTFDGRSYSFWGGQGCRYSLVQDYVKG------QLLILLEHGACDAGSCLHAISVSLE 624
HY++FDGR + F G C Y LV + ++L+ EH S A+ V
Sbjct: 932 HYVSFDGRRFDFMG--TCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEAR 989
Query: 625 DTHIQLRDS--GAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVA 681
+ +R G VLV+ LP+ A+G + V R ++ G V + + V
Sbjct: 990 GVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVT 1049
Query: 682 YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ--------VAGKGR 733
+ +A + GLCG F + DD G + AF + +Q G
Sbjct: 1050 -AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGD 1108
Query: 734 CPSEDSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCD 791
CP DS + + ++ C IL F+ECH +D + C+ C
Sbjct: 1109 CPKLDSLVAQQLQSKNE--------CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1160
Query: 792 PGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---P 847
S LC L+ YA C GA+ PWR++ LCP+ CP Y C+ C CG P
Sbjct: 1161 GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVP 1220
Query: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM--KECNR-CIC 904
CG C GC C G E C+P + C C + PG C+ C C
Sbjct: 1221 GGCG--SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1277
Query: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
QE GL +C + C C P+G + GCV +
Sbjct: 1278 QEGGLVSCESSSCGPHEACQ-----------------------PSGGSLGCVAVGSST-- 1312
Query: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
C+ SG PHY T
Sbjct: 1313 -----------CQASGD--------------------------------------PHYTT 1323
Query: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRL 1072
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++
Sbjct: 1324 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQV 1376
Score = 75.1 bits (183), Expect = 2e-12
Identities = 129/543 (23%), Positives = 175/543 (32%), Gaps = 127/543 (23%)
Query: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
+P C CPA C CP C+ C + C +GC C G + G CVP
Sbjct: 798 SPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFVASGGACVP 856
Query: 4114 IGHCDCTDAQGHSWAPGSQ-----------------HQDACNN---------CSCQAGQL 4147
C CT QG APG + HQ C + CS Q G L
Sbjct: 857 ASSCGCT-FQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 915
Query: 4148 SC------TAQPCPPPTHCAWS--HWSAWSPCSH----SCGPRGQQSRFR--------SS 4187
C T Q P + ++ + C++ SCG FR S
Sbjct: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS 975
Query: 4188 TSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICED 4247
+ S+ R E + + P L + L G+ Q + V+ D
Sbjct: 976 QTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 1035
Query: 4248 TECAVPEAWT------LWSSWSDCPVS-CGG--GNQVRTRACRAAAPHHRSPPCLGPDTQ 4298
V W + SS+++ CG G+ A R ++ L
Sbjct: 1036 FGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG---QAANALAFGNS 1092
Query: 4299 TRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCP---CLMAKADPTCNSTFLHLDTQ 4355
+++ PG CG A+ G CP L+A+ + N + D +
Sbjct: 1093 WQEETRPG----------------CG---ATEPGDCPKLDSLVAQQLQSKNECGILADPK 1133
Query: 4356 G----CYSGPCPE----ECVWSSWSSWTRCSCRVLVQQRYRHQGPASRG-ARAGAPCTRL 4406
G C+S P+ +CV+ RC +L Q GP A A C
Sbjct: 1134 GPFRECHSKLDPQGAVRDCVYD------RC---LLPGQ----SGPLCDALATYAAACQAA 1180
Query: 4407 DGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLP-------PCQPGC 4459
P SC P + AC C LS C DLP C GC
Sbjct: 1181 GATVHPWRSEELCPLSCPPHSHYEACSYGCP------LS---CGDLPVPGGCGSECHEGC 1231
Query: 4460 YCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAPGDRLQLGCKE-CECRRGEL-HCTS 4516
C +G C+P C C H G T PG GC C C+ G L C S
Sbjct: 1232 VCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES 1287
Query: 4517 QGC 4519
C
Sbjct: 1288 SSC 1290
Score = 74.7 bits (182), Expect = 2e-12
Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + C+ G P SC +L P G CH GC C G L C+P C C
Sbjct: 1194 PLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCV 1253
Query: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
H+G +PPG T C++ C C G + +C S C P C S G
Sbjct: 1254 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG----------PHEACQPSGGSL 1303
Query: 3203 RC 3204
C
Sbjct: 1304 GC 1305
Score = 61.2 bits (147), Expect = 3e-08
Identities = 45/123 (36%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
C CP SC C PC GC C PG + G CVP SSC C +LA
Sbjct: 815 CGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGL----QLA 870
Query: 4738 PAQAVQLD--CQ-NCTC--VNESLVC-PHQECPVLGPWSAWSSCSAPCG--GGTMERHRT 4789
P Q V D CQ CTC + C Q CP A CS G G +R T
Sbjct: 871 PGQEVWADELCQRRCTCNGATHQVTCRDKQSCP------AGERCSVQNGLLGCYPDRFGT 924
Query: 4790 CEG 4792
C+G
Sbjct: 925 CQG 927
Score = 59.3 bits (142), Expect = 1e-07
Identities = 44/141 (31%), Positives = 51/141 (36%), Gaps = 30/141 (21%)
Query: 2590 GGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCS 2649
G P S+E P P S C G CP SC D C
Sbjct: 1181 GATVHPWRSEELCPLSCPPHSHYEACSYG----------------CPLSCGDLPVPGGCG 1224
Query: 2650 GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG-NC-SQCVCEKGELL- 2706
C EGC C G L CLPL+ C C+ PG +F G C S C C++G L+
Sbjct: 1225 SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVS 1284
Query: 2707 -----------CQPGGCPLPC 2716
CQP G L C
Sbjct: 1285 CESSSCGPHEACQPSGGSLGC 1305
Score = 58.2 bits (139), Expect = 2e-07
Identities = 73/259 (28%), Positives = 89/259 (34%), Gaps = 63/259 (24%)
Query: 3600 QSRSAGSRFSSW-ESLEPGEVVTGPCDNCTCVAGIL--QCQEVPDC---PDPGVWSSWGP 3653
Q+ +A + +SW E PG T P D C + ++ Q Q +C DP GP
Sbjct: 1082 QAANALAFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPK-----GP 1135
Query: 3654 WEDCSVSCGGGEQLRS---RRCARPPCPGPARQSRTCSTQVCREAG-------------- 3696
+ +C +R RC P GP + C+ AG
Sbjct: 1136 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1195
Query: 3697 -CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQECPC 3753
CP Y C GCP SC + GC SE C EGC C EG +C + C C
Sbjct: 1196 SCPPHSHYEACS--YGCPLSCGDLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGC 1252
Query: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKL-SCSLDDCFEADG 3812
V T PGQ PG DS C C G L SC C
Sbjct: 1253 VHQ--------GTYHPPGQTFYPGPGCDS---------LCHCQEGGLVSCESSSC----- 1290
Query: 3813 GFGPWSPWGPCSRSCGGLG 3831
P C S G LG
Sbjct: 1291 -----GPHEACQPSGGSLG 1304
Score = 56.2 bits (134), Expect = 8e-07
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CP C+ CP C DL C + C +GC C +G C+P+ C
Sbjct: 1193 CPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSE--CHEGCVCDEGFALSGESCLPLASC 1250
Query: 4118 DCTDAQGHSWAPGSQHQ--DACNN-CSCQAGQL-SCTAQPCPPPTHC 4160
C QG PG C++ C CQ G L SC + C P C
Sbjct: 1251 GCVH-QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEAC 1296
Score = 54.7 bits (130), Expect = 2e-06
Identities = 39/125 (31%), Positives = 46/125 (36%), Gaps = 11/125 (8%)
Query: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
CP CP C +CP C + C PC GC C G + G CVP ++C
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
Query: 4874 CTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVA 4933
CT L L E A EL RC C+G + D Q P V
Sbjct: 862 CTFQGLQ--LAPGQEVWADELCQ--------RRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
Query: 4934 PGELG 4938
G LG
Sbjct: 912 NGLLG 916
Score = 52.8 bits (125), Expect = 9e-06
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 18/118 (15%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLHNASCL 2940
C CP N + E C G CP C C+G C GC C PG +C+
Sbjct: 802 CPLSCPANSRY---ELC---GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACV 855
Query: 2941 PRSQCPCQLHG-------QLYASGAMARLDSCNNC----TCVSGKMACTSERCPVACG 2987
P S C C G +++A R +CN TC + ERC V G
Sbjct: 856 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNG 913
Score = 52.4 bits (124), Expect = 1e-05
Identities = 64/241 (26%), Positives = 85/241 (35%), Gaps = 35/241 (14%)
Query: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC-PVLGPWSA-----WSSCSAP 4778
CG +L A QL +N + P +EC L P A + C P
Sbjct: 1101 CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1160
Query: 4779 CGGGTMERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCW 4836
G + C+ A CQA + + CP CPP AC+ CP C
Sbjct: 1161 GQSGPL-----CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1215
Query: 4837 HLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPP 4896
L C E C GC C G L +C+P +C C T Q P
Sbjct: 1216 DLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGCVHQG-------TYHPPGQTFYP 1267
Query: 4897 GTVLTRNC-TRCVC-HGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQS 4954
G C + C C GG SC C P E Q + G LG C+ + ++ Q+
Sbjct: 1268 GP----GCDSLCHCQEGGLVSCESSSC--GPHEACQP-SGGSLG-----CVAVGSSTCQA 1315
Query: 4955 N 4955
+
Sbjct: 1316 S 1316
Score = 52.0 bits (123), Expect = 2e-05
Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 27/140 (19%)
Query: 3289 DYCEGPRAQGEVCQALPCPVTNCTAIEG------------------AEYSPCGPPCPRSC 3330
D C P G +C AL C A + Y C CP SC
Sbjct: 1155 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSC 1214
Query: 3331 DDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDG 3387
DL C C GC C G LS G C+ C C+ G H PG G
Sbjct: 1215 GDLPVPGGCGSECHEGCVCDEGFALS--GESCLPLASCGCVH--QGTYHPPGQTFYPGPG 1270
Query: 3388 CNH-CTCLEGRL-NCTDLPC 3405
C+ C C EG L +C C
Sbjct: 1271 CDSLCHCQEGGLVSCESSSC 1290
Score = 50.8 bits (120), Expect = 3e-05
Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 17/116 (14%)
Query: 3291 CEGPRAQGEVCQALPCPV------TNC--TAIEGAEYSPCGPPCPRSCDDLV---HCVWR 3339
C G A + C L V NC + + Y CGP CP SC+ +C R
Sbjct: 776 CRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR 835
Query: 3340 -CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGC-NHCTC 3393
C GC C PG V S G CV C C G + PG + + C CTC
Sbjct: 836 PCVEGCVCLPGFVAS--GGACVPASSCGC--TFQGLQLAPGQEVWADELCQRRCTC 887
Score = 50.8 bits (120), Expect = 3e-05
Identities = 48/172 (27%), Positives = 68/172 (39%), Gaps = 25/172 (14%)
Query: 73 LCPIYKPPETRPAKWNRTVRTCC-----PGWGGAHCTEALAKASPEGHCFAMWQCQLQAG 127
LCP+ PP + + C PG G+ C E EG + C
Sbjct: 1192 LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGESCL---- 1245
Query: 128 SANASAGSLEECCARPWGQSWWDGSSQACRS---CSSRHLPGSASSPA----LLQPLAGA 180
AS G + + P GQ+++ G C S C L SS QP G+
Sbjct: 1246 -PLASCGCVHQGTYHPPGQTFYPGPG--CDSLCHCQEGGLVSCESSSCGPHEACQPSGGS 1302
Query: 181 VGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH 232
+G + S+TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 1303 LGCV----AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH 1350
Score = 49.7 bits (117), Expect = 8e-05
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 2633 PPCPPSCLDPKANRSCSGH-CVEGCRCPPGLLLHDTRCLPLSECPC 2677
P CP SC A +CSG CVEGC C PG + C+P S C C
Sbjct: 817 PACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
Score = 47.4 bits (111), Expect = 4e-04
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 19/144 (13%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPC 3144
P CP + ++ C P SC +AP + + C GC C G + CVP C C
Sbjct: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
Query: 3145 AHEGHLYPPGSTV------VRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSAS 3198
+G PG V R C C+ + + C GE +CS
Sbjct: 863 TFQGLQLAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAGE----------RCSVQ 911
Query: 3199 CGPARCHRHRFCARSPSAVPSTVA 3222
G C+ RF S P V+
Sbjct: 912 NGLLGCYPDRFGTCQGSGDPHYVS 935
Score = 47.0 bits (110), Expect = 5e-04
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 37/230 (16%)
Query: 4836 WHLQPGAICVQEPCQPGC-GCPGGQLLH---NGTCV-------PPTACPCTQHSLPWGLT 4884
W L G ++ CQ C C GQ H + C P C T P+
Sbjct: 701 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPF--- 757
Query: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHG-GAFSCSLVDCQVPPGETWQQVAPGELG----- 4938
LE+ +L + +C G A++ + ++ + G+ W+ A L
Sbjct: 758 --LEQCVYDL----CVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLSCPANS 810
Query: 4939 ---LCEQTC-LEMNATKTQSNCSSARA-SGCVCQPGHFRSQAGPCVPEDHCECWHLGRPH 4993
LC C N SNCS GCVC PG F + G CVP C C G
Sbjct: 811 RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQL 869
Query: 4994 LPGSE-W-QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG--SCCP 5039
PG E W E C+ +G +C GE ++ G C P
Sbjct: 870 APGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 1807 CPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWP 1865
CP +C ++ C P CP +C+ + C PC GC C G V S G CV
Sbjct: 802 CP-LSCPANSRYELCGPACPTSCNGAAAPSNCSGR-PCVE-GCVCLPGFV-ASGGACVPA 857
Query: 1866 RQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLN 1903
C C G + PGQ + AD +LC RRC N
Sbjct: 858 SSCGCTFQGLQLAPGQEVWAD-ELC------QRRCTCN 888
Score = 45.1 bits (105), Expect = 0.002
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 15/106 (14%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
CPA Y C P CP SC C C EGC C G ACV C
Sbjct: 806 CPANSRYELCGPA--CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSC--- 860
Query: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
G T G L PG E+ + + + C C+ A +++C
Sbjct: 861 -------GCTF--QGLQLAPGQEVWADELCQRRC-TCNGATHQVTC 896
Score = 43.1 bits (100), Expect = 0.007
Identities = 33/133 (24%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 2854 GRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQ 2912
G C +LA C + ++ C CP + + + CP C
Sbjct: 1164 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY------GCPLSCGDL 1217
Query: 2913 GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASG-AMARLDSCNN-CTC 2970
C C GC C G L SCLP + C C G + G C++ C C
Sbjct: 1218 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1277
Query: 2971 VSGKM-ACTSERC 2982
G + +C S C
Sbjct: 1278 QEGGLVSCESSSC 1290
Score = 42.7 bits (99), Expect = 0.009
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 14/105 (13%)
Query: 3486 MCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRS 3545
+C G S ++AC G P N S C CG CP S
Sbjct: 775 LCRGLSAYAQACLELGISVGDWRSPANCPLS------------CPANSRYELCGPACPTS 822
Query: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ 3590
C + S C C C C G ++ G CVP + C C +Q
Sbjct: 823 CNGAAAPSNCSGRP--CVEGCVCLPGFVASGGACVPASSCGCTFQ 865
Score = 42.0 bits (97), Expect = 0.016
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 6/84 (7%)
Query: 4642 AEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCR 4701
A G PW E CP + C+ CP SC DL C C
Sbjct: 1175 AACQAAGATVHPWRSEELCPLSCPPHSHYEA-----CSYGCPLSCGDLPVPGGC-GSECH 1228
Query: 4702 PGCRCPPGQLVQDGRCVPISSCRC 4725
GC C G + C+P++SC C
Sbjct: 1229 EGCVCDEGFALSGESCLPLASCGC 1252
Score = 41.6 bits (96), Expect = 0.021
Identities = 73/320 (22%), Positives = 95/320 (29%), Gaps = 94/320 (29%)
Query: 3057 GGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGPASCAELSAPRGT 3115
GGG S E + G C PG CP+ D Q C L+ P+G
Sbjct: 1079 GGGQAANALAFGNSWQEETRPG---CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1135
Query: 3116 NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCS 3175
+ CH P G + C ++ L P S + C ++ A C
Sbjct: 1136 FRECHSKLD-PQGAVR-----------DCVYDRCLLPGQSGPL-----CDALATYAAACQ 1178
Query: 3176 SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235
+ T PW C SC P H P + LP+P
Sbjct: 1179 A-----AGATVHPWRSEELCPLSCPP-----HSHYEACSYGCPLSCGDLPVP-------- 1220
Query: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPR 3295
GG G S C C CD EG
Sbjct: 1221 -----------------GGCG-----SECHEGC---------VCD-----------EGFA 1238
Query: 3296 AQGEVCQALPCPVTNCTAIEGAEYSPCGP---PCPRSCDDLVHC----VWRCQPGCYCPP 3348
GE C P+ +C + Y P G P P CD L HC + C+ P
Sbjct: 1239 LSGESC----LPLASCGCVHQGTYHPPGQTFYPGP-GCDSLCHCQEGGLVSCESSSCGPH 1293
Query: 3349 GQVLSSNGAI-CVQPGHCSC 3367
S G++ CV G +C
Sbjct: 1294 EACQPSGGSLGCVAVGSSTC 1313
Score = 40.4 bits (93), Expect = 0.046
Identities = 53/203 (26%), Positives = 66/203 (32%), Gaps = 50/203 (24%)
Query: 3477 PWGPWSPCDMCLGQSHRSRAC--SRPPTP-EGGRPCPGNHTQSRPCQ---------ENST 3524
P GP+ C L R C R P + G C T + CQ +
Sbjct: 1132 PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEE 1191
Query: 3525 QCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVG--CQPTCGCPLGQLSQDGLCVP 3581
C C C CP SC DL PG G C C C G C+P
Sbjct: 1192 LCPLSCPPHSHYEACSYGCPLSCGDLPV-----PGGCGSECHEGCVCDEGFALSGESCLP 1246
Query: 3582 PAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTC-VAGILQCQEV 3639
A C C +Q G+ ++ PG CD+ C C G++ C+
Sbjct: 1247 LASCGCVHQ--------------GTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES- 1287
Query: 3640 PDCPDPGVWSSWGPWEDCSVSCG 3662
SS GP E C S G
Sbjct: 1288 ---------SSCGPHEACQPSGG 1301
Score = 38.9 bits (89), Expect = 0.13
Identities = 31/101 (30%), Positives = 35/101 (34%), Gaps = 8/101 (7%)
Query: 4940 CEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
C C L C S GCVC G F C+P C C H G H PG
Sbjct: 1206 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQT 1264
Query: 4999 WQ--EACES-CLCLSGRPVCTQHCSPLTCAQGEEMVLEPGS 5036
+ C+S C C G V C +C E GS
Sbjct: 1265 FYPGPGCDSLCHCQEGGLV---SCESSSCGPHEACQPSGGS 1302
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 286 bits (732), Expect = 4e-76
Identities = 243/955 (25%), Positives = 392/955 (41%), Gaps = 112/955 (11%)
Query: 71 PGLCPIYKPPETRPAKWNRTVR-TCCPGWGGAHCTEALAKASP--EGHCFAMWQC--QLQ 125
P CP+ PP ++ + + TC G+ G C++ +A G + +C + Q
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
Query: 126 AGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLW 185
G + AGS + G+ W+ + C S + Q G ++
Sbjct: 1479 CGCLHP-AGSYFKV-----GERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY 1532
Query: 186 SQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL-----AGAADSTWAVHLTPGDR-- 238
H + +ATC + HY TFDG +HF+G CTY+L + + DS + V T +R
Sbjct: 1533 GCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGG 1592
Query: 239 CPQPGHCQRVTMGPEEV---LIQAGNVSVKGQLVPEGQSWLLHG-LSLQWLGDWLVLSGG 294
+ + + V + ++ L++ V + G V WL G ++++ + ++L
Sbjct: 1593 ILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL-PVWLAQGRVTIRLSSNLVLLYTN 1651
Query: 295 LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354
G+ VR D + + ++V GQ GLCG YN DD + P LA + G +W+L
Sbjct: 1652 FGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKL 1711
Query: 355 P-GSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLL--EGPFGQCHAQVSP 411
P SE GC C + DA C L+ +GPF QCH V P
Sbjct: 1712 PESSEPGCFLVGGKPSSCQENSMADA----------WNKNCAILINPQGPFSQCHQVVPP 1761
Query: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPG 471
+C+ C G +G A+C + +Y CA+ WR FC CP
Sbjct: 1762 QSSFASCVHGQC-------GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPP 1814
Query: 472 GQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC----- 526
G YS C S CP +C ++ + C CEC +G +GT CVP C C
Sbjct: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
Query: 527 --YYCRQRYVPGDTVRQLC------------------NPCVCRDGRWHCAQALCPAECAV 566
+ +R+ +T +LC C DG C +A C +
Sbjct: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC-RASGVGVCQL 1933
Query: 567 GGDGHYLTFDGRSYSFWGG------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAIS 620
G+ HY++FDG ++S + C ++ + K E G +A LH +
Sbjct: 1934 PGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFR-LHEVY 1992
Query: 621 VSLEDTHIQLRDSGAVLVNGQDVGLPWIG-AEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679
+ + D + L+ VL+N + V LP I G+SV+ +S ++ G QV + +
Sbjct: 1993 IDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD-GNH 2051
Query: 680 VAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ-----------V 728
+ I + + +V G+CG F ++D+ + P+ +V S + F + ++ +
Sbjct: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
Query: 729 AGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVC 788
+ + P+E S + E A L + V+ +C +D PF + C +C
Sbjct: 2112 VDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLC 2171
Query: 789 GCDPGSDCLCPVLSAYARRCAQEGASPP-WRNQTLCPVMCPGGQEYRECAPACGQHC--- 844
LC L A+ C +G PP WRN + CP+ CP Y C P+C C
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231
Query: 845 -GKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAP-GSATMKE--CN 900
G+ E +C GC C G + E +CVP S C C+ P G + +
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPGYVLS-EDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290
Query: 901 RCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGC 955
+C+C G C CPS + C LT D ++N +C + ++ C
Sbjct: 2291 KCVC-TGGAIQCGDFRCPSGSHCQ-----------LTSD--NSNSNCVSDKSEQC 2331
Score = 285 bits (730), Expect = 6e-76
Identities = 242/857 (28%), Positives = 346/857 (40%), Gaps = 107/857 (12%)
Query: 182 GQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADSTWAVHLTPGD 237
GQ +ATC + HY TFDGRH+ F+G+CTY+LA + D + V +
Sbjct: 1143 GQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEE 1202
Query: 238 RCPQPGHCQR---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGG 294
+ + C VT+ V + G ++ G + G+ L G ++ L
Sbjct: 1203 QGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE 1262
Query: 295 LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354
G+ VR D + ++V G+ GLCG Y+G ++D ++ G A GNSW+
Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
Query: 355 PGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQD--VCHQLLE--GPFGQCHAQVS 410
E Q C ++++ L++ C +L++ GPF C V
Sbjct: 1323 DQDED---------QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVK 1373
Query: 411 PAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARR-HIHIRWRKPGFCERLC 469
A + ++C+ C G +G Q +C ++ C H WR+P FC C
Sbjct: 1374 AASFFDSCMLDMC-------GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
Query: 470 PGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY- 528
P YS C CP +C + G C + CV CEC G +G C+P + C C +
Sbjct: 1427 PPNSKYSLCAKPCPDTCHSGFSGM--FCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 529 ---------------CRQRYVPGDTVRQLCNPCVCR--------DGRWHCAQALCPAECA 565
C++ V R C P CR DG + C A A C
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGC-HAQGAATCT 1543
Query: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQD-YVKGQLLILL------EHGACDAGSCLHA 618
GD HYLTFDG + F G C Y L + + + Q + G S + A
Sbjct: 1544 ASGDPHYLTFDGALHHFMGT--CTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
Query: 619 ISVSLEDTHIQLRDSGAVLVNGQDVGLP-WIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
+ V++ D I L V++NG V LP W+ +++R +S+ LL G QV + S
Sbjct: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
Query: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSE 737
V +T+ + Q+ GLCG + N DD L P + +A + + A K SE
Sbjct: 1662 HLVE-VTVPSSYGGQLCGLCGNYNNNSLDDNLRP----DRKLAGDSMQLGAAWKLPESSE 1716
Query: 738 DSALL-----SPCTTHSQRHAFAEAACAILHS--SVFQECHRLVDKEPFYLRCLAAVCGC 790
L S C +S A+ + CAIL + F +CH++V + + C+ CG
Sbjct: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
Query: 791 DPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKP 847
+ LC L AYA CAQ G +P WRN+T CP+ CP G Y C+ C C P
Sbjct: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP 1835
Query: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSA---TMKECNR-CI 903
DC + C C C G + CVP C C A Y P T C R C
Sbjct: 1836 RDCPKALPCAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
Query: 904 CQERGLWNCTARHCPSQAFC------PRELVYAPGACLLTCDS-----PSANHSCPAGST 952
C C C C R G C L +S +NHS P
Sbjct: 1895 CSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIP---- 1950
Query: 953 DGC------VCPPGTVL 963
D C VC P L
Sbjct: 1951 DACTLVLVKVCHPAMAL 1967
Score = 264 bits (674), Expect = 2e-69
Identities = 246/949 (25%), Positives = 363/949 (38%), Gaps = 189/949 (19%)
Query: 469 CPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY 528
CP Y C CP SC++ SC C GC C G ++ C+ A+ C C+Y
Sbjct: 1044 CPPNARYESCA--CPASCKS----PRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
Query: 529 CRQRYVPGD-------TVRQLCNP----------------CVCRDGRWHCAQALCPAECA 565
Y PG T C P C ++G++ C A C
Sbjct: 1098 NNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
Query: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG-----QLLILLEHGACDAGSCLHAIS 620
V GD HY+TFDGR + F G C Y L Q ++ E + SCL +
Sbjct: 1158 VYGDPHYVTFDGRHFGFMG--KCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 621 VSLEDTHIQLRDSGAVLVNGQDVGLP-------WIGAEGLSVRRASSAFLLLRWPGAQVL 673
V+L ++ + L LV GQ V LP ++GA G V + L +RW G Q L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 674 WGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFL----TPAGDVETSIAAF------- 722
Y+T+ ++ ++ GLCG + N +D L +PAGD E ++
Sbjct: 1276 --------YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
Query: 723 --ASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEP 778
K+QV PS DS+L S + C L + F+ C V
Sbjct: 1328 QECQKYQVVNS---PSCDSSLQSSMS--------GPGFCGRLVDTHGPFETCLLHVKAAS 1376
Query: 779 FYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECA 837
F+ C+ +CG LC +S C G A PWR CP+ CP +Y CA
Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
Query: 838 PACGQHCGKPED---CGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPC--------QLGA 886
C C C + CV C C G + +C+P S C C ++G
Sbjct: 1437 KPCPDTCHSGFSGMFCSD--RCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGE 1493
Query: 887 RRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRE----LVYAPGACLLTCDSPS 942
R Y PG + C+C+ C C +Q FC ++ +A GA TC +
Sbjct: 1494 RWYKPGCKEL-----CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAA--TCTASG 1546
Query: 943 ANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQ 1002
H T +L C R +++ +A
Sbjct: 1547 DPHYLTFDGALHHFMGTCTYVLTRPCW------SRSQDSYFVVSA--------------- 1585
Query: 1003 WHCTGQRRSGRCQAS--GAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGAS 1060
T + R G + S A H FD L+ + C+ +L L AQ
Sbjct: 1586 ---TNENRGGILEVSYIKAVHVTVFD-LSISLLRGCKVMLNGHRVALPVWLAQG------ 1635
Query: 1061 GLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGL 1120
+ +RL +V +YT GL +R
Sbjct: 1636 ------RVTIRLSSNLV------------------LLYTNFGLQVR-------------- 1657
Query: 1121 TLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASND-LRSRQGVLEPTAELAAHSWRL-- 1177
+DG V V + + G++ GLCG+++ ++ +D LR + + + +L A +W+L
Sbjct: 1658 ---YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGA-AWKLPE 1713
Query: 1178 --SPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDA 1233
P C G P C N+ W + C L+ P F+ CH VPPQ + C++
Sbjct: 1714 SSEPGCFLVGGKPSSCQENSMADAWNK-NCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772
Query: 1234 CGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCH 1293
CG + GD LC ++ YA CA+ G WR++ C ++C G Y C CP TC
Sbjct: 1773 CG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
Query: 1294 EQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPP 1342
+ P + + C E C C +G +L G +C+ C C S+ P
Sbjct: 1831 SIN-NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHP 1878
Score = 214 bits (545), Expect = 2e-54
Identities = 154/538 (28%), Positives = 219/538 (40%), Gaps = 72/538 (13%)
Query: 923 CPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG-- 980
CP Y AC +C SP SC +GCVC PG + D C+ C C ++
Sbjct: 1044 CPPNARYESCACPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
Query: 981 -----QWYLPNATIQEDC----------------NVCVCRGRQWHCTGQRRSGRCQASGA 1019
+W+ PN T C VC + Q+ C + C G
Sbjct: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
Query: 1020 PHYVTFDGLAFTYPGACEYLLVREASG----LFTVSAQNLPCGASGLTCTKALAVRLEGT 1075
PHYVTFDG F + G C Y+L + F V+A+N G G++C + V L +
Sbjct: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
Query: 1076 VVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLS 1135
V +L+GR V G VT P + G+ L +G F+ L T GL + WDG ++ V +S
Sbjct: 1222 TVTLLKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVS 1280
Query: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEPGDLPHP- 1190
+ G++ GLCG++DG++ ND G E +SW+ C + + P
Sbjct: 1281 STYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPS 1340
Query: 1191 CTMNTHRAGWARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
C + + CG L+ F C V ++ C+ D CG G LC+
Sbjct: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTH 1398
Query: 1249 IATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA 1307
++T C GH V+ WR C + C Y C CP TCH G C
Sbjct: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF--SGMFCS-DR 1455
Query: 1308 CVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGG 1367
CVE C C G +L G C+ + C C P GS + +W+ G
Sbjct: 1456 CVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVG--------ERWYKPG--- 1499
Query: 1368 HCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSS 1425
C+EL +C+ N W C Q+ CG GC A +G TC++
Sbjct: 1500 -CKEL--------CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHA----QGAATCTA 1544
Score = 166 bits (420), Expect = 6e-40
Identities = 152/603 (25%), Positives = 234/603 (38%), Gaps = 76/603 (12%)
Query: 838 PACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEG------QCVPP--SLCPC---QLGA 886
P C GKP C E S N +L +P+G Q VPP S C Q G
Sbjct: 1717 PGCFLVGGKPSSCQE-NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
Query: 887 RRYAPGSATMKECNRCICQERG---LWNCTARHCPSQAFCPRELVYAP--GACLLTCDSP 941
+ + +C + G W CP + CP Y+P C TC S
Sbjct: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWR-NRTFCPMR--CPPGSSYSPCSSPCPDTCSSI 1832
Query: 942 SANHSCPAG--STDGCVCPPGTVLLDERCVPPDLCPCRHSG--------QWYLPNATIQE 991
+ CP + C C G +L CVP C C +WY N +
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 992 ---------DCNVCVCRGRQ--WHCTGQRRS-----GRCQASGAPHYVTFDGLAFTYPGA 1035
C C+ Q W G R G CQ G HYV+FDG + P A
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1036 CEYLLVRE-----ASGLFTVSAQN-LPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNG 1089
C +LV+ A F +SA++ G + + + + V + +G V +N
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS 2012
Query: 1090 VSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDF 1149
VT P + PG+S++ + ++ +++ +G+ + +DG + +++ + G+V G+CG+F
Sbjct: 2013 KQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNF 2072
Query: 1150 DGDASNDLRSRQGVLEPTAELAAHSWR---LSPLCPE--------PGDLPHPCTMNTHRA 1198
+ + ++L + + +SW+ + P C P + + N A
Sbjct: 2073 NDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAA 2132
Query: 1199 GWARAR--CGALLQ-PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
RAR C A L+ P++ C + + C C+ GG + LC A+ +
Sbjct: 2133 DLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGAT 2190
Query: 1256 CARHG-HHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314
C G WR+ C L+C Y C P+C P+C + AC EGC C
Sbjct: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
Query: 1315 PEGTLLHGGACLEPASCPCEWGR-NSFPPG-SVLQKDC-GNCTCQEGQWHCGG----DGG 1367
G +L C+ + C C+ S P G S + C C C G CG G
Sbjct: 2251 QPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310
Query: 1368 HCE 1370
HC+
Sbjct: 2311 HCQ 2313
Score = 163 bits (413), Expect = 4e-39
Identities = 223/994 (22%), Positives = 361/994 (36%), Gaps = 138/994 (13%)
Query: 74 CPIYKPPETRPAKWNRTVRTCCPGWGGAH-CTEALAKASP----EGHCFAMWQC-QLQAG 127
CP+ PP + + + C C +AL A +GH + C L
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 128 SANASAGSLEECCARPWGQSWW-DGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWS 186
AGS P G+ W+ + + +CS + S + A+ L
Sbjct: 1868 GCTDPAGSYH-----PVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
Query: 187 QHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAV---HLTPGDRCPQPG 243
C HY +FDG ++ CT +L A+ ++ + G
Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
Query: 244 ------HCQRVTMGPEEVLIQAGN-VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLG 296
H + + +V +Q G+ V + + V + G+S++ + +++ +G
Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
Query: 297 VVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPG 356
V V+ D + I + +G+ G+CG +N ED+ M P +A + F NSW+
Sbjct: 2043 VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD 2102
Query: 357 SESGCLDAVEVAQGCDPLGLIDADVEPGHLRA----EAQDVCHQLLEGP-FGQCHAQVSP 411
+ C + Q + + G+ RA A++ C L P + QC +++
Sbjct: 2103 IDPSCQSLLVDEQ---QIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
Query: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCP 470
+ CA + G G QA+C ++ C + + WR FC CP
Sbjct: 2160 TPF-----LVDCANTLCEFG--GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
Query: 471 GGQLYSDCVSLCPPSC-EAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYC 529
Y++C+ C PSC + G+ E C GC C G + CVP + C C
Sbjct: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDA 2272
Query: 530 RQRYVP--GDTVRQLCNP-CVCRDGRWHCAQALCPA---------------------ECA 565
+P V C CVC G C CP+ +C+
Sbjct: 2273 HGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCS 2332
Query: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACD-----AGSCLHAIS 620
V GD YLTFDG SY G D + + LL G + L +
Sbjct: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVI 2392
Query: 621 VSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPV 680
++ +QL+ ++VN Q + +P+ E L V L+ V +G
Sbjct: 2393 TTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFG-GRKN 2451
Query: 681 AYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKG-------R 733
A I+L + V GLCG + +N+++D + P+G + ++ F + ++V +
Sbjct: 2452 AVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRA 2511
Query: 734 CPSEDSA-----------LLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFY 780
P+E+ +S C+ Q + + AC +L F CH+ V EPF
Sbjct: 2512 IPAEEEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQ 2570
Query: 781 LRCLAAVCGC-DP--GSDCLCPVLSAYARRCAQEGASPPWR----NQTLCPVMCPGGQEY 833
C+ +C DP + C VLS + G S + TL ++C G+
Sbjct: 2571 EHCVLDLCSAQDPREQEELRCQVLSGH-------GVSSRYHISELYDTLPSILCQPGRPR 2623
Query: 834 RECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGS 893
P G+ P C L W PE P + C C Y GS
Sbjct: 2624 GLRGPLRGRLRQHPRLC---------------LQWHPE---PPLADCGCTSNGIYYQLGS 2665
Query: 894 ATMKE--CNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSC---- 947
+ + E RC C + C C + C L C +SP + C
Sbjct: 2666 SFLTEDCSQRCTCASSRILLCEPFSCRAGEVC--TLGNHTQGCF--PESPCLQNPCQNDG 2721
Query: 948 ---PAGSTDGCVCP---PGTVLLDERCVPPDLCP 975
G+T C C G + ++ R PP P
Sbjct: 2722 QCREQGATFTCECEVGYGGGLCMEPRDAPPPRKP 2755
Score = 124 bits (310), Expect = 3e-27
Identities = 139/570 (24%), Positives = 204/570 (35%), Gaps = 117/570 (20%)
Query: 904 CQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSC------------PAGS 951
CQ +GL R+ +FCP E P T PS + SC P+
Sbjct: 2191 CQSQGLKPPLWRN---SSFCPLE---CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC 2244
Query: 952 TDGCVCPPGTVLLDERCVPPDLCPCR--HSGQWYLPNATIQEDCNV-CVCRGRQWHCTGQ 1008
+GC+C PG VL +++CVP C C+ H G L + + C CVC G C
Sbjct: 2245 AEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDF 2304
Query: 1009 R---------------------RSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL 1047
R +S +C G P Y+TFDG ++ G Y+L++ L
Sbjct: 2305 RCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVL 2364
Query: 1048 ------FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGP 1101
V +N + + + G V + G + VN + P
Sbjct: 2365 PEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNE 2423
Query: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQ 1161
L + G L L T L + + G ++ L + G V+GLCG++D + ND+
Sbjct: 2424 HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPS 2483
Query: 1162 GVLEPTAELAAHSWRL---SPLCPEPGDLP------------------HPCTMNTHRAGW 1200
G L +SW + L P +P C+ +
Sbjct: 2484 GALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNS 2543
Query: 1201 ARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECL-CSAIATYADECA 1257
+A C L P F CH V P+ E C+ D C + E L C ++ +
Sbjct: 2544 TQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHG---V 2599
Query: 1258 RHGHHVRWRSQELCSLQCEGGQVYEACGP------TCPPTCHEQHPEP----------GW 1301
+H+ L S+ C+ G+ GP P C + HPEP G
Sbjct: 2600 SSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGI 2659
Query: 1302 HCQVVA------CVEGCFCPEGTLLHGGACLEPASC----PCEWGRNS---FPPGSVLQK 1348
+ Q+ + C + C C +L EP SC C G ++ FP LQ
Sbjct: 2660 YYQLGSSFLTEDCSQRCTCASSRIL----LCEPFSCRAGEVCTLGNHTQGCFPESPCLQN 2715
Query: 1349 DC---GNCTCQEGQWHC----GGDGGHCEE 1371
C G C Q + C G GG C E
Sbjct: 2716 PCQNDGQCREQGATFTCECEVGYGGGLCME 2745
Score = 66.2 bits (160), Expect = 8e-10
Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 4/107 (3%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CP G C++ CP CS + C C + C C KG + CVP+G C
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 4118 DCTDAQGHSWAPGSQ--HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160
CTD G G + ++ C C+C ++C C P C
Sbjct: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
Score = 63.5 bits (153), Expect = 5e-09
Identities = 37/96 (38%), Positives = 43/96 (44%), Gaps = 19/96 (19%)
Query: 2626 LCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCL------- 2678
LC K PCP +C + CS CVE C C PG +L C+P S+C CL
Sbjct: 1434 LCAK----PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYF 1489
Query: 2679 -VGEELKWPGVSFLLGNCSQCVCE-KGELLCQPGGC 2712
VGE PG L CVCE + CQP C
Sbjct: 1490 KVGERWYKPGCKEL------CVCESNNRIRCQPWRC 1519
Score = 61.6 bits (148), Expect = 2e-08
Identities = 41/138 (29%), Positives = 53/138 (38%), Gaps = 8/138 (5%)
Query: 4040 GAPCAGERHQARLC-NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQV---CQ 4095
GA C + + L N C CPA C C C DL C+ +V C
Sbjct: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR--CEGAKVPSACA 2245
Query: 4096 KGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQ--HQDACNNCSCQAGQLSCTAQP 4153
+GC C G + + CVP C C DA G S G C C G + C
Sbjct: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFR 2305
Query: 4154 CPPPTHCAWSHWSAWSPC 4171
CP +HC + ++ S C
Sbjct: 2306 CPSGSHCQLTSDNSNSNC 2323
Score = 60.5 bits (145), Expect = 4e-08
Identities = 48/173 (27%), Positives = 66/173 (38%), Gaps = 35/173 (20%)
Query: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGC 4853
A CQ+Q + N CP ECP + C SC CW L + P C GC
Sbjct: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGC 2248
Query: 4854 GCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPG-TVLTRNCT-RCVCHG 4911
C G +L CVP + C C + +P G + ++ CT +CVC G
Sbjct: 2249 ICQPGYVLSEDKCVPRSQCGCK------------DAHGGSIPLGKSWVSSGCTEKCVCTG 2296
Query: 4912 GAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGC 4964
GA C D + P G Q + + + SNC S ++ C
Sbjct: 2297 GAIQCG--DFRCPSGSHCQ----------------LTSDNSNSNCVSDKSEQC 2331
Score = 59.7 bits (143), Expect = 7e-08
Identities = 30/80 (37%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CP SC P+ SC C EGC C PG L D C+ S C C + PG + N
Sbjct: 1055 CPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112
Query: 2695 CSQ-CVCEKGELL-CQPGGC 2712
C++ C C G + CQ C
Sbjct: 1113 CTEHCRCWPGSRVECQISQC 1132
Score = 58.5 bits (140), Expect = 2e-07
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 15/113 (13%)
Query: 2878 NTQPCTAQCPE-----NMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGL 2932
N+ C +CP N L + C G C G + CA GC C PG
Sbjct: 2203 NSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCE--------GAKVPSACAEGCICQPGY 2254
Query: 2933 FLHNASCLPRSQCPCQ-LHGQLYASGAMARLDSC-NNCTCVSGKMACTSERCP 2983
L C+PRSQC C+ HG G C C C G + C RCP
Sbjct: 2255 VLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
Score = 58.5 bits (140), Expect = 2e-07
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 2632 VPPCPPSCLDPKANRSCSGH-----CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWP 2686
+P C PSC D + C G C EGC C PG +L + +C+P S+C C P
Sbjct: 2221 LPSCSPSCWD--LDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIP 2278
Query: 2687 -GVSFLLGNCSQ-CVCEKGELLCQPGGCP 2713
G S++ C++ CVC G + C CP
Sbjct: 2279 LGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
Score = 58.2 bits (139), Expect = 2e-07
Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 12/131 (9%)
Query: 2857 CSSLAPGDTTCPGP-HSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
C+ ++ TTC H+ C CP N + + PCP C + G
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK------PCPDTCHSGFSG 1449
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLH--GQLYASGAMARLDSCNN-CTCVS 2972
+ C+ C C C PG L C+PRSQC C LH G + G C C C S
Sbjct: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCES 1508
Query: 2973 -GKMACTSERC 2982
++ C RC
Sbjct: 1509 NNRIRCQPWRC 1519
Score = 57.4 bits (137), Expect = 4e-07
Identities = 59/202 (29%), Positives = 74/202 (36%), Gaps = 38/202 (18%)
Query: 3237 PEAEEEPCLLQG-----CDR---AGGWG--------PWGPWSHCSRSCGGGLRSRTRACD 3280
PE+ E C L G C A W P GP+S C + +S +C
Sbjct: 1712 PESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPP--QSSFASCV 1769
Query: 3281 QPPPQGLGD---YCEGPRAQGEVC-QALPCPV----TNCT--AIEGAEYSPCGPPCPRSC 3330
GD C +A +C QA P T C G+ YSPC PCP +C
Sbjct: 1770 HGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
Query: 3331 DDLVH---C--VWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP 3385
+ + C C C C G +LS G CV G C C D G H G R
Sbjct: 1830 SSINNPRDCPKALPCAESCECQKGHILS--GTSCVPLGQCGCTD-PAGSYHPVGERWYTE 1886
Query: 3386 DGCNH-CTC-LEGRLNCTDLPC 3405
+ C CTC + + C C
Sbjct: 1887 NTCTRLCTCSVHNNITCFQSTC 1908
Score = 57.0 bits (136), Expect = 5e-07
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 3/120 (2%)
Query: 4759 PHQEC-PVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCP- 4816
P +C V+ P S+++SC G + C A AQ + N CP
Sbjct: 1751 PFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPM 1810
Query: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQE-PCQPGCGCPGGQLLHNGTCVPPTACPCT 4875
CPPG S C++ CP C + C + PC C C G +L +CVP C CT
Sbjct: 1811 RCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCT 1870
Score = 53.9 bits (128), Expect = 4e-06
Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 25/134 (18%)
Query: 3291 CEGPRAQGEVCQALP-----------CPVTNCTAIEGAEYSPCGPPCPRSCDDL------ 3333
C+ +A G CQ+ CP+ C A + Y+ C P C SC DL
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPL-ECPAY--SSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 3334 VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CT 3392
C GC C PG VLS + CV C C D G P + GC C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDK--CVPRSQCGCKDAHGGS--IPLGKSWVSSGCTEKCV 2293
Query: 3393 CLEGRLNCTDLPCP 3406
C G + C D CP
Sbjct: 2294 CTGGAIQCGDFRCP 2307
Score = 53.1 bits (126), Expect = 7e-06
Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 13/117 (11%)
Query: 3090 CPRDKQWLDCAQGPASCAELSAPRGT-NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
CP + ++ CA PASC +PR + C GC C G L +N C+ C C +
Sbjct: 1044 CPPNARYESCAC-PASC---KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 3149 HLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCH 3205
Y PG+ P NC+ +C WP + E S + C G CH
Sbjct: 1100 DYYEPGAEWFSP--NCT------EHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
Score = 53.1 bits (126), Expect = 7e-06
Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 18/114 (15%)
Query: 4660 NGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGR 4716
N CP EC A + +C C SC DL R + + P C GC C PG ++ + +
Sbjct: 2203 NSSFCPLECPAYSSY--TNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK 2260
Query: 4717 CVPISSCRC-----GLPSANASWELAPAQAVQLDC-QNCTCVNESLVCPHQECP 4764
CVP S C C G SW V C + C C ++ C CP
Sbjct: 2261 CVPRSQCGCKDAHGGSIPLGKSW-------VSSGCTEKCVCTGGAIQCGDFRCP 2307
Score = 52.4 bits (124), Expect = 1e-05
Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 36/211 (17%)
Query: 4890 QAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNA 4949
Q+Q L P L RN + C A+S S +C L C +C +++
Sbjct: 2192 QSQGLKPP--LWRNSSFCPLECPAYS-SYTNC---------------LPSCSPSCWDLDG 2233
Query: 4950 TKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP-GSEWQEA--CESC 5006
+ SA A GC+CQPG+ S+ CVP C C +P G W + E C
Sbjct: 2234 RCEGAKVPSACAEGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKC 2292
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFT-KG 5065
+C G C C G L + +C ++S C + + R T G
Sbjct: 2293 VCTGG----AIQCGDFRCPSGSHCQLTSDNSNSNC----VSDKSEQCSVYGDPRYLTFDG 2344
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPE--EPYL 5094
Y Q ++Y + V+PE EP L
Sbjct: 2345 FSYRLQGRMTY---VLIKTVDVLPEGVEPLL 2372
Score = 52.0 bits (123), Expect = 2e-05
Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 9/102 (8%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481
+C P ++ C PC C + S C D C C C G + CIP +C C
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPRSQCGCL 1482
Query: 4482 HTSAAGAGMTLAPGDR-LQLGCKE-CECR-RGELHCTSQGCQ 4520
H AG G+R + GCKE C C + C C+
Sbjct: 1483 HP----AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCR 1520
Score = 51.2 bits (121), Expect = 3e-05
Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 8/91 (8%)
Query: 3317 AEYSPCGPPCPRSCDD-LVHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQR 3375
A Y C CP SC C C+ GC C PG + S N C+Q C+C
Sbjct: 1048 ARYESCA--CPASCKSPRPSCGPLCREGCVCNPGFLFSDNH--CIQASSCNC--FYNNDY 1101
Query: 3376 HHPGARLARPDGCNHCTCLEG-RLNCTDLPC 3405
+ PGA P+ HC C G R+ C C
Sbjct: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
Score = 50.4 bits (119), Expect = 4e-05
Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 12/102 (11%)
Query: 2883 TAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPR 2942
T +CP N + S CP C + P C C GC C PG + C+
Sbjct: 1041 TERCPPNARYESCA--------CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQA 1090
Query: 2943 SQCPCQLHGQLYASGAMARLDSC-NNCTCVSG-KMACTSERC 2982
S C C + Y GA +C +C C G ++ C +C
Sbjct: 1091 SSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
Score = 50.4 bits (119), Expect = 4e-05
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Query: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD 3576
P N T C C G S PC PCP +C ++ C P ++ C +C C G +
Sbjct: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDC-PKALPCAESCECQKGHILSG 1858
Query: 3577 GLCVPPAHCRCQYQPGA 3593
CVP C C G+
Sbjct: 1859 TSCVPLGQCGCTDPAGS 1875
Score = 49.3 bits (116), Expect = 1e-04
Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 5/109 (4%)
Query: 4055 PMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPI 4114
P C CP + CA CP C G+ C D C + C C G + C+P
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPR 1476
Query: 4115 GHCDCTDAQGHSWAPGSQ-HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160
C C G + G + ++ C C C++ ++ C C C
Sbjct: 1477 SQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFC 1525
Score = 48.1 bits (113), Expect = 2e-04
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 3317 AEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTG 3373
++YS C PCP +C + C RC C C PG VLS G C+ C CL G
Sbjct: 1430 SKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLS--GLECIPRSQCGCLH-PAG 1486
Query: 3374 QRHHPGARLARPDGCNH-CTC-LEGRLNCTDLPC 3405
G R +P GC C C R+ C C
Sbjct: 1487 SYFKVGERWYKP-GCKELCVCESNNRIRCQPWRC 1519
Score = 48.1 bits (113), Expect = 2e-04
Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCA-PCPLTCDDISGQ 1834
C S Q CA G + R CP P ++ + PC+ PCP TC I+
Sbjct: 1783 CRSLQAYASLCAQA-GQAPAWRNRTFCPMRCPPGSS------YSPCSSPCPDTCSSINNP 1835
Query: 1835 VTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWP-GQRIKAD---CQLC 1890
CP PC + C C +G +L CV QC C Y P G+R + +LC
Sbjct: 1836 RDCPKALPC-AESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
Query: 1891 IC 1892
C
Sbjct: 1894 TC 1895
Score = 47.8 bits (112), Expect = 3e-04
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C P + C SPC C++ + + C PC C C KG + C+P +C C
Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC-- 1869
Query: 4483 TSAAGA 4488
T AG+
Sbjct: 1870 TDPAGS 1875
Score = 46.2 bits (108), Expect = 8e-04
Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 4678 CANQCPHSCADLWDRVQCLQG-PCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWEL 4736
C++ CP +C+ + + C + PC C C G ++ CVP+ C C P A + +
Sbjct: 1821 CSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP-AGSYHPV 1879
Query: 4737 APAQAVQLDCQN-CTC-VNESLVCPHQEC 4763
+ C CTC V+ ++ C C
Sbjct: 1880 GERWYTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 45.8 bits (107), Expect = 0.001
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 4/101 (3%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + ++ CA+ P +C + + C C C G +L C+P C C
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCL 1482
Query: 3146 H-EGHLYPPGSTVVRP-C-ENCSCVSGLIANCSSWPCAEGE 3183
H G + G +P C E C C S C W C E
Sbjct: 1483 HPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQE 1523
Score = 44.7 bits (104), Expect = 0.002
Identities = 49/209 (23%), Positives = 69/209 (33%), Gaps = 30/209 (14%)
Query: 2778 WTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWA 2837
W S C GG P + + + + +C + P S VP
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADA-WNKNCAILINPQGPFSQCHQVVP------- 1760
Query: 2838 PWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRS 2894
P S+ ++ G T+G + C SL + C N C +CP +
Sbjct: 1761 PQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSP 1820
Query: 2895 AEQCHQEGGPCPRLCLTQGPGIECTGF--CAPGCTCPPGLFLHNASCLPRSQCPC----- 2947
PCP C + +C CA C C G L SC+P QC C
Sbjct: 1821 CSS------PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
Query: 2948 ---QLHGQLYASGAMARLDSC---NNCTC 2970
+ + Y RL +C NN TC
Sbjct: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITC 1903
Score = 43.9 bits (102), Expect = 0.004
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
CP CPP S CA CP C G C + C C C G +L C+P + C
Sbjct: 1422 CPMACPPNSKYSLCAKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRSQCG 1480
Query: 4874 C 4874
C
Sbjct: 1481 C 1481
Score = 43.9 bits (102), Expect = 0.004
Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 23/129 (17%)
Query: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSV--GCQPTCGCPLGQLS 3574
P NS+ C +C S C C SC DL C+ V C C C G +
Sbjct: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVL 2256
Query: 3575 QDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGIL 3634
+ CVP + C C+ G IP + SW V +G + C C G +
Sbjct: 2257 SEDKCVPRSQCGCKDAHGG-SIPLGK---------SW-------VSSGCTEKCVCTGGAI 2299
Query: 3635 QCQEVPDCP 3643
QC + CP
Sbjct: 2300 QCGDF-RCP 2307
Score = 43.9 bits (102), Expect = 0.004
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 8/103 (7%)
Query: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAP---RGTNQTCHPGCHCPSGMLLLNNVCVPTQDC 3142
P CP + +C + SC +L C GC C G +L + CVP C
Sbjct: 2208 PLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQC 2267
Query: 3143 PC--AHEGHLYPPGSTVVRPC-ENCSCVSGLIANCSSWPCAEG 3182
C AH G + S V C E C C G I C + C G
Sbjct: 2268 GCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAI-QCGDFRCPSG 2309
Score = 43.5 bits (101), Expect = 0.005
Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 20/146 (13%)
Query: 3059 GYRNRTRGSSRSLMEFSTCGLQPCAGPV-------PGMCPRDKQWLDCAQG-PASCAELS 3110
G + T RSL +++ Q P P CP + C+ P +C+ ++
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
Query: 3111 APRGTNQT--CHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPP-------GSTVVRPC 3161
PR + C C C G +L CVP C C Y P +T R C
Sbjct: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
Query: 3162 ENCSCVSGLIANCSSWPCAEGEPTWS 3187
CS + + C C + W+
Sbjct: 1894 -TCSVHNNI--TCFQSTCKPNQICWA 1916
Score = 42.7 bits (99), Expect = 0.009
Identities = 22/45 (48%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 4682 CPHSCADLWDRVQCLQGP-CRPGCRCPPGQLVQDGRCVPISSCRC 4725
CP SC R C GP CR GC C PG L D C+ SSC C
Sbjct: 1055 CPASCKS--PRPSC--GPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
Score = 42.7 bits (99), Expect = 0.009
Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 2634 PCPPSCLDPKANRSCSGH--CVEGCRCPPGLLLHDTRCLPLSECPC 2677
PCP +C R C C E C C G +L T C+PL +C C
Sbjct: 1824 PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
Score = 42.0 bits (97), Expect = 0.016
Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTD 4121
CP +CA CP C + +C++GC C G L D C+ C+C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSC----GPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
Query: 4122 AQGHSWAPGSQ--HQDACNNCSCQAG-QLSCTAQPCPPPTHC 4160
+ + PG++ + +C C G ++ C C T C
Sbjct: 1098 NNDY-YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
Score = 42.0 bits (97), Expect = 0.016
Identities = 28/114 (24%), Positives = 41/114 (35%), Gaps = 26/114 (22%)
Query: 4924 PPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
PP ++ A C +C + +C GCVC PG S C+
Sbjct: 1045 PPNARYESCA------CPASC-----KSPRPSCGPLCREGCVCNPGFLFSD-NHCIQASS 1092
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSC 5037
C C++ + PG+EW P CT+HC C G + + C
Sbjct: 1093 CNCFYNNDYYEPGAEWFS-----------PNCTEHC---RCWPGSRVECQISQC 1132
Score = 40.8 bits (94), Expect = 0.035
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 4648 GGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCP 4707
G +PW + CP ++ ++L CA CP +C + + C C C C
Sbjct: 1410 GHAVKPWREPHF----CPMACPPNSKYSL-CAKPCPDTCHSGFSGMFC-SDRCVEACECN 1463
Query: 4708 PGQLVQDGRCVPISSCRCGLPSAN 4731
PG ++ C+P S C C P+ +
Sbjct: 1464 PGFVLSGLECIPRSQCGCLHPAGS 1487
Score = 38.5 bits (88), Expect = 0.17
Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 22/107 (20%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQH 4877
CPP +CA CP C +P + C+ GC C G L + C+ ++C C +
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCT-RCVCHGGAFSCSLVDCQV 4923
+ + E A+ P NCT C C G S V+CQ+
Sbjct: 1099 NDYY------EPGAEWFSP------NCTEHCRCWPG----SRVECQI 1129
Score = 37.7 bits (86), Expect = 0.30
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 6/69 (8%)
Query: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPP 4475
S S + C P + +C P + C + C P C+ GC C G L CI
Sbjct: 1037 SRSSTERCPPNARYESCACPAS--CKS--PRPSCG--PLCREGCVCNPGFLFSDNHCIQA 1090
Query: 4476 EECNCWHTS 4484
CNC++ +
Sbjct: 1091 SSCNCFYNN 1099
Score = 37.4 bits (85), Expect = 0.39
Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 5/109 (4%)
Query: 3485 DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPR 3544
DMC Q + C+ T C +P +E C C +PCP
Sbjct: 1384 DMCGFQGLQHLLCTHMSTMT--TTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPD 1441
Query: 3545 SCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGA 3593
+C G C S C C C G + C+P + C C + G+
Sbjct: 1442 TCHSGFSGMFC---SDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGS 1487
Score = 37.4 bits (85), Expect = 0.39
Identities = 48/164 (29%), Positives = 63/164 (38%), Gaps = 22/164 (13%)
Query: 1883 IKADCQLCICQDGRPRRCRLNPDCAVDCG-WSSWSPWAKCLGPCGSQSIQWSFRSSNNPR 1941
++A LC Q G+ R C + C SS+SP C PC + S NNPR
Sbjct: 1786 LQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSP---CSSPCPD-----TCSSINNPR 1836
Query: 1942 PSGRGRQC-------RGIHRKARRCQTEPCEGC-EHQGQVHRVGERWH-GGPC-RVCQCL 1991
+ C +G C GC + G H VGERW+ C R+C C
Sbjct: 1837 DCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
Query: 1992 --HNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTV 2033
+N+T S P C L+ C LPGE+ V
Sbjct: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYV 1940
Score = 36.6 bits (83), Expect = 0.66
Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 4455 CQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKE-CECRRGELH 4513
C GC C G + C+P +C C A G + L + GC E C C G +
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGK-SWVSSGCTEKCVCTGGAIQ 2300
Query: 4514 CTSQGC 4519
C C
Sbjct: 2301 CGDFRC 2306
Score = 36.2 bits (82), Expect = 0.87
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 7/76 (9%)
Query: 4956 CSSARASGCVCQPGHFRSQAGPCVPEDHCECWH-LGRPHLPGSEW-QEAC-ESCLCLSGR 5012
CS C C PG S C+P C C H G G W + C E C+C S
Sbjct: 1452 CSDRCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNN 1510
Query: 5013 PVCTQHCSPLTCAQGE 5028
+ C P C E
Sbjct: 1511 RI---RCQPWRCRAQE 1523
Score = 35.4 bits (80), Expect = 1.5
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 10/57 (17%)
Query: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QYQPGA 3593
CP SC+ SP C P C+ C C G L D C+ + C C Y+PGA
Sbjct: 1055 CPASCK--SPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGA 1106
Score = 35.4 bits (80), Expect = 1.5
Identities = 29/115 (25%), Positives = 39/115 (33%), Gaps = 22/115 (19%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSE-GCEEGCHCPEGTFQHRLACVQ--ECPC 3753
CP G Y C CP +C+ + C C E C C +G +CV +C C
Sbjct: 1812 CPPGSSYSPCS--SPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
Query: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCA-HGKLSCSLDDC 3807
DP P E T T C+C+ H ++C C
Sbjct: 1870 T--------------DPAGSYHPVGE--RWYTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 35.0 bits (79), Expect = 1.9
Identities = 35/142 (24%), Positives = 49/142 (34%), Gaps = 27/142 (19%)
Query: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
GP+E C + S C C Q C+ T C++AG
Sbjct: 1363 GPFETCLLHVKAASFFDS--CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPH 1420
Query: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--Q 3749
CP Y C + CP +C + C S+ C E C C G L C+
Sbjct: 1421 FCPMACPPNSKYSLC--AKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRS 1477
Query: 3750 ECPCVLTAWLLQELGATIGDPG 3771
+C C+ A ++G PG
Sbjct: 1478 QCGCLHPAGSYFKVGERWYKPG 1499
Score = 34.7 bits (78), Expect = 2.5
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 26/140 (18%)
Query: 4130 GSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSH----------WSAWSPCSHSCGPRG 4179
G +Q C + QA +C +Q PP W + +S+++ C SC P
Sbjct: 2174 GGLYQALCQ--ALQAFGATCQSQGLKPPL---WRNSSFCPLECPAYSSYTNCLPSCSPSC 2228
Query: 4180 QQSRFRSSTSGSWAPECREEQSQSQP---CPQPSCPPLCLQGTR-----SRTLGDSWLQG 4231
R G+ P E QP + C P G + S LG SW+
Sbjct: 2229 WDLDGRCE--GAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS 2286
Query: 4232 EC-QRCSCTPEGVICEDTEC 4250
C ++C CT + C D C
Sbjct: 2287 GCTEKCVCTGGAIQCGDFRC 2306
Score = 33.9 bits (76), Expect = 4.3
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
Query: 3138 PTQDCPCAHEGHLYPPGST-VVRPC-ENCSCVSGLIANCSSWPCAEGE 3183
P DC C G Y GS+ + C + C+C S I C + C GE
Sbjct: 2648 PLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGE 2695
Score = 33.5 bits (75), Expect = 5.6
Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 36/115 (31%)
Query: 1795 STRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQ 1854
S T+ CP PNA ++ CA CP +C S + +C P GC C G
Sbjct: 1037 SRSSTERCP----PNAR------YESCA-CPASCK--SPRPSCGP---LCREGCVCNPG- 1079
Query: 1855 VLGSEGWCVWPRQCPCLVDGARY-----------------WPGQRIKADCQLCIC 1892
L S+ C+ C C + Y WPG R+ +CQ+ C
Sbjct: 1080 FLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRV--ECQISQC 1132
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 286 bits (732), Expect = 4e-76
Identities = 243/955 (25%), Positives = 392/955 (41%), Gaps = 112/955 (11%)
Query: 71 PGLCPIYKPPETRPAKWNRTVR-TCCPGWGGAHCTEALAKASP--EGHCFAMWQC--QLQ 125
P CP+ PP ++ + + TC G+ G C++ +A G + +C + Q
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
Query: 126 AGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLW 185
G + AGS + G+ W+ + C S + Q G ++
Sbjct: 1479 CGCLHP-AGSYFKV-----GERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY 1532
Query: 186 SQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL-----AGAADSTWAVHLTPGDR-- 238
H + +ATC + HY TFDG +HF+G CTY+L + + DS + V T +R
Sbjct: 1533 GCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGG 1592
Query: 239 CPQPGHCQRVTMGPEEV---LIQAGNVSVKGQLVPEGQSWLLHG-LSLQWLGDWLVLSGG 294
+ + + V + ++ L++ V + G V WL G ++++ + ++L
Sbjct: 1593 ILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL-PVWLAQGRVTIRLSSNLVLLYTN 1651
Query: 295 LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354
G+ VR D + + ++V GQ GLCG YN DD + P LA + G +W+L
Sbjct: 1652 FGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKL 1711
Query: 355 P-GSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLL--EGPFGQCHAQVSP 411
P SE GC C + DA C L+ +GPF QCH V P
Sbjct: 1712 PESSEPGCFLVGGKPSSCQENSMADA----------WNKNCAILINPQGPFSQCHQVVPP 1761
Query: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPG 471
+C+ C G +G A+C + +Y CA+ WR FC CP
Sbjct: 1762 QSSFASCVHGQC-------GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPP 1814
Query: 472 GQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC----- 526
G YS C S CP +C ++ + C CEC +G +GT CVP C C
Sbjct: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
Query: 527 --YYCRQRYVPGDTVRQLC------------------NPCVCRDGRWHCAQALCPAECAV 566
+ +R+ +T +LC C DG C +A C +
Sbjct: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC-RASGVGVCQL 1933
Query: 567 GGDGHYLTFDGRSYSFWGG------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAIS 620
G+ HY++FDG ++S + C ++ + K E G +A LH +
Sbjct: 1934 PGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFR-LHEVY 1992
Query: 621 VSLEDTHIQLRDSGAVLVNGQDVGLPWIG-AEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679
+ + D + L+ VL+N + V LP I G+SV+ +S ++ G QV + +
Sbjct: 1993 IDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD-GNH 2051
Query: 680 VAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ-----------V 728
+ I + + +V G+CG F ++D+ + P+ +V S + F + ++ +
Sbjct: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
Query: 729 AGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVC 788
+ + P+E S + E A L + V+ +C +D PF + C +C
Sbjct: 2112 VDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLC 2171
Query: 789 GCDPGSDCLCPVLSAYARRCAQEGASPP-WRNQTLCPVMCPGGQEYRECAPACGQHC--- 844
LC L A+ C +G PP WRN + CP+ CP Y C P+C C
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231
Query: 845 -GKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAP-GSATMKE--CN 900
G+ E +C GC C G + E +CVP S C C+ P G + +
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPGYVLS-EDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290
Query: 901 RCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGC 955
+C+C G C CPS + C LT D ++N +C + ++ C
Sbjct: 2291 KCVC-TGGAIQCGDFRCPSGSHCQ-----------LTSD--NSNSNCVSDKSEQC 2331
Score = 285 bits (730), Expect = 6e-76
Identities = 242/857 (28%), Positives = 346/857 (40%), Gaps = 107/857 (12%)
Query: 182 GQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADSTWAVHLTPGD 237
GQ +ATC + HY TFDGRH+ F+G+CTY+LA + D + V +
Sbjct: 1143 GQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEE 1202
Query: 238 RCPQPGHCQR---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGG 294
+ + C VT+ V + G ++ G + G+ L G ++ L
Sbjct: 1203 QGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE 1262
Query: 295 LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354
G+ VR D + ++V G+ GLCG Y+G ++D ++ G A GNSW+
Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
Query: 355 PGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQD--VCHQLLE--GPFGQCHAQVS 410
E Q C ++++ L++ C +L++ GPF C V
Sbjct: 1323 DQDED---------QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVK 1373
Query: 411 PAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARR-HIHIRWRKPGFCERLC 469
A + ++C+ C G +G Q +C ++ C H WR+P FC C
Sbjct: 1374 AASFFDSCMLDMC-------GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
Query: 470 PGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY- 528
P YS C CP +C + G C + CV CEC G +G C+P + C C +
Sbjct: 1427 PPNSKYSLCAKPCPDTCHSGFSGM--FCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 529 ---------------CRQRYVPGDTVRQLCNPCVCR--------DGRWHCAQALCPAECA 565
C++ V R C P CR DG + C A A C
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGC-HAQGAATCT 1543
Query: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQD-YVKGQLLILL------EHGACDAGSCLHA 618
GD HYLTFDG + F G C Y L + + + Q + G S + A
Sbjct: 1544 ASGDPHYLTFDGALHHFMGT--CTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
Query: 619 ISVSLEDTHIQLRDSGAVLVNGQDVGLP-WIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
+ V++ D I L V++NG V LP W+ +++R +S+ LL G QV + S
Sbjct: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
Query: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSE 737
V +T+ + Q+ GLCG + N DD L P + +A + + A K SE
Sbjct: 1662 HLVE-VTVPSSYGGQLCGLCGNYNNNSLDDNLRP----DRKLAGDSMQLGAAWKLPESSE 1716
Query: 738 DSALL-----SPCTTHSQRHAFAEAACAILHS--SVFQECHRLVDKEPFYLRCLAAVCGC 790
L S C +S A+ + CAIL + F +CH++V + + C+ CG
Sbjct: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
Query: 791 DPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKP 847
+ LC L AYA CAQ G +P WRN+T CP+ CP G Y C+ C C P
Sbjct: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP 1835
Query: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSA---TMKECNR-CI 903
DC + C C C G + CVP C C A Y P T C R C
Sbjct: 1836 RDCPKALPCAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
Query: 904 CQERGLWNCTARHCPSQAFC------PRELVYAPGACLLTCDS-----PSANHSCPAGST 952
C C C C R G C L +S +NHS P
Sbjct: 1895 CSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIP---- 1950
Query: 953 DGC------VCPPGTVL 963
D C VC P L
Sbjct: 1951 DACTLVLVKVCHPAMAL 1967
Score = 264 bits (674), Expect = 2e-69
Identities = 246/949 (25%), Positives = 363/949 (38%), Gaps = 189/949 (19%)
Query: 469 CPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY 528
CP Y C CP SC++ SC C GC C G ++ C+ A+ C C+Y
Sbjct: 1044 CPPNARYESCA--CPASCKS----PRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
Query: 529 CRQRYVPGD-------TVRQLCNP----------------CVCRDGRWHCAQALCPAECA 565
Y PG T C P C ++G++ C A C
Sbjct: 1098 NNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
Query: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG-----QLLILLEHGACDAGSCLHAIS 620
V GD HY+TFDGR + F G C Y L Q ++ E + SCL +
Sbjct: 1158 VYGDPHYVTFDGRHFGFMG--KCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 621 VSLEDTHIQLRDSGAVLVNGQDVGLP-------WIGAEGLSVRRASSAFLLLRWPGAQVL 673
V+L ++ + L LV GQ V LP ++GA G V + L +RW G Q L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 674 WGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFL----TPAGDVETSIAAF------- 722
Y+T+ ++ ++ GLCG + N +D L +PAGD E ++
Sbjct: 1276 --------YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
Query: 723 --ASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEP 778
K+QV PS DS+L S + C L + F+ C V
Sbjct: 1328 QECQKYQVVNS---PSCDSSLQSSMS--------GPGFCGRLVDTHGPFETCLLHVKAAS 1376
Query: 779 FYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECA 837
F+ C+ +CG LC +S C G A PWR CP+ CP +Y CA
Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
Query: 838 PACGQHCGKPED---CGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPC--------QLGA 886
C C C + CV C C G + +C+P S C C ++G
Sbjct: 1437 KPCPDTCHSGFSGMFCSD--RCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGE 1493
Query: 887 RRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRE----LVYAPGACLLTCDSPS 942
R Y PG + C+C+ C C +Q FC ++ +A GA TC +
Sbjct: 1494 RWYKPGCKEL-----CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAA--TCTASG 1546
Query: 943 ANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQ 1002
H T +L C R +++ +A
Sbjct: 1547 DPHYLTFDGALHHFMGTCTYVLTRPCW------SRSQDSYFVVSA--------------- 1585
Query: 1003 WHCTGQRRSGRCQAS--GAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGAS 1060
T + R G + S A H FD L+ + C+ +L L AQ
Sbjct: 1586 ---TNENRGGILEVSYIKAVHVTVFD-LSISLLRGCKVMLNGHRVALPVWLAQG------ 1635
Query: 1061 GLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGL 1120
+ +RL +V +YT GL +R
Sbjct: 1636 ------RVTIRLSSNLV------------------LLYTNFGLQVR-------------- 1657
Query: 1121 TLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASND-LRSRQGVLEPTAELAAHSWRL-- 1177
+DG V V + + G++ GLCG+++ ++ +D LR + + + +L A +W+L
Sbjct: 1658 ---YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGA-AWKLPE 1713
Query: 1178 --SPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDA 1233
P C G P C N+ W + C L+ P F+ CH VPPQ + C++
Sbjct: 1714 SSEPGCFLVGGKPSSCQENSMADAWNK-NCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772
Query: 1234 CGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCH 1293
CG + GD LC ++ YA CA+ G WR++ C ++C G Y C CP TC
Sbjct: 1773 CG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
Query: 1294 EQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPP 1342
+ P + + C E C C +G +L G +C+ C C S+ P
Sbjct: 1831 SIN-NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHP 1878
Score = 214 bits (545), Expect = 2e-54
Identities = 154/538 (28%), Positives = 219/538 (40%), Gaps = 72/538 (13%)
Query: 923 CPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG-- 980
CP Y AC +C SP SC +GCVC PG + D C+ C C ++
Sbjct: 1044 CPPNARYESCACPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
Query: 981 -----QWYLPNATIQEDC----------------NVCVCRGRQWHCTGQRRSGRCQASGA 1019
+W+ PN T C VC + Q+ C + C G
Sbjct: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
Query: 1020 PHYVTFDGLAFTYPGACEYLLVREASG----LFTVSAQNLPCGASGLTCTKALAVRLEGT 1075
PHYVTFDG F + G C Y+L + F V+A+N G G++C + V L +
Sbjct: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
Query: 1076 VVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLS 1135
V +L+GR V G VT P + G+ L +G F+ L T GL + WDG ++ V +S
Sbjct: 1222 TVTLLKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVS 1280
Query: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEPGDLPHP- 1190
+ G++ GLCG++DG++ ND G E +SW+ C + + P
Sbjct: 1281 STYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPS 1340
Query: 1191 CTMNTHRAGWARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
C + + CG L+ F C V ++ C+ D CG G LC+
Sbjct: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTH 1398
Query: 1249 IATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA 1307
++T C GH V+ WR C + C Y C CP TCH G C
Sbjct: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF--SGMFCS-DR 1455
Query: 1308 CVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGG 1367
CVE C C G +L G C+ + C C P GS + +W+ G
Sbjct: 1456 CVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVG--------ERWYKPG--- 1499
Query: 1368 HCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSS 1425
C+EL +C+ N W C Q+ CG GC A +G TC++
Sbjct: 1500 -CKEL--------CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHA----QGAATCTA 1544
Score = 175 bits (443), Expect = 1e-42
Identities = 204/885 (23%), Positives = 333/885 (37%), Gaps = 110/885 (12%)
Query: 74 CPIYKPPETRPAKWNRTVRTCCPGWGGAH-CTEALAKASP----EGHCFAMWQC-QLQAG 127
CP+ PP + + + C C +AL A +GH + C L
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 128 SANASAGSLEECCARPWGQSWW-DGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWS 186
AGS P G+ W+ + + +CS + S + A+ L
Sbjct: 1868 GCTDPAGSYH-----PVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
Query: 187 QHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAV---HLTPGDRCPQPG 243
C HY +FDG ++ CT +L A+ ++ + G
Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
Query: 244 ------HCQRVTMGPEEVLIQAGN-VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLG 296
H + + +V +Q G+ V + + V + G+S++ + +++ +G
Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
Query: 297 VVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPG 356
V V+ D + I + +G+ G+CG +N ED+ M P +A + F NSW+
Sbjct: 2043 VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD 2102
Query: 357 SESGCLDAVEVAQGCDPLGLIDADVEPGHLRA----EAQDVCHQLLEGP-FGQCHAQVSP 411
+ C + Q + + G+ RA A++ C L P + QC +++
Sbjct: 2103 IDPSCQSLLVDEQ---QIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
Query: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCP 470
+ CA + G G QA+C ++ C + + WR FC CP
Sbjct: 2160 TPF-----LVDCANTLCEFG--GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
Query: 471 GGQLYSDCVSLCPPSC-EAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYC 529
Y++C+ C PSC + G+ E C GC C G + CVP + C C
Sbjct: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDA 2272
Query: 530 RQRYVP--GDTVRQLCNP-CVCRDGRWHCAQALCPA---------------------ECA 565
+P V C CVC G C CP+ +C+
Sbjct: 2273 HGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCS 2332
Query: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACD-----AGSCLHAIS 620
V GD YLTFDG SY G D + + LL G + L +
Sbjct: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVI 2392
Query: 621 VSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPV 680
++ +QL+ ++VN Q + +P+ E L V L+ V +G
Sbjct: 2393 TTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFG-GRKN 2451
Query: 681 AYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKG-------R 733
A I+L + V GLCG + +N+++D + P+G + ++ F + ++V +
Sbjct: 2452 AVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRA 2511
Query: 734 CPSEDSA-----------LLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFY 780
P+E+ +S C+ Q + + AC +L F CH+ V EPF
Sbjct: 2512 IPAEEEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQ 2570
Query: 781 LRCLAAVCGC-DP--GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYREC 836
C+ +C DP + C VLS YA C + GA+ WR++TLC
Sbjct: 2571 EHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCE------------ 2618
Query: 837 APACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCP 881
+P C C E G+ C C +G G C+ P P
Sbjct: 2619 SPCLQNPCQNDGQCREQGATFT-CECEVGY---GGGLCMEPRDAP 2659
Score = 166 bits (420), Expect = 6e-40
Identities = 152/603 (25%), Positives = 234/603 (38%), Gaps = 76/603 (12%)
Query: 838 PACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEG------QCVPP--SLCPC---QLGA 886
P C GKP C E S N +L +P+G Q VPP S C Q G
Sbjct: 1717 PGCFLVGGKPSSCQE-NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
Query: 887 RRYAPGSATMKECNRCICQERG---LWNCTARHCPSQAFCPRELVYAP--GACLLTCDSP 941
+ + +C + G W CP + CP Y+P C TC S
Sbjct: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWR-NRTFCPMR--CPPGSSYSPCSSPCPDTCSSI 1832
Query: 942 SANHSCPAG--STDGCVCPPGTVLLDERCVPPDLCPCRHSG--------QWYLPNATIQE 991
+ CP + C C G +L CVP C C +WY N +
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 992 ---------DCNVCVCRGRQ--WHCTGQRRS-----GRCQASGAPHYVTFDGLAFTYPGA 1035
C C+ Q W G R G CQ G HYV+FDG + P A
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1036 CEYLLVRE-----ASGLFTVSAQN-LPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNG 1089
C +LV+ A F +SA++ G + + + + V + +G V +N
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS 2012
Query: 1090 VSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDF 1149
VT P + PG+S++ + ++ +++ +G+ + +DG + +++ + G+V G+CG+F
Sbjct: 2013 KQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNF 2072
Query: 1150 DGDASNDLRSRQGVLEPTAELAAHSWR---LSPLCPE--------PGDLPHPCTMNTHRA 1198
+ + ++L + + +SW+ + P C P + + N A
Sbjct: 2073 NDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAA 2132
Query: 1199 GWARAR--CGALLQ-PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
RAR C A L+ P++ C + + C C+ GG + LC A+ +
Sbjct: 2133 DLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGAT 2190
Query: 1256 CARHG-HHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314
C G WR+ C L+C Y C P+C P+C + AC EGC C
Sbjct: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
Query: 1315 PEGTLLHGGACLEPASCPCEWGR-NSFPPG-SVLQKDC-GNCTCQEGQWHCGG----DGG 1367
G +L C+ + C C+ S P G S + C C C G CG G
Sbjct: 2251 QPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310
Query: 1368 HCE 1370
HC+
Sbjct: 2311 HCQ 2313
Score = 120 bits (301), Expect = 3e-26
Identities = 120/496 (24%), Positives = 176/496 (35%), Gaps = 94/496 (18%)
Query: 904 CQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSC------------PAGS 951
CQ +GL R+ +FCP E P T PS + SC P+
Sbjct: 2191 CQSQGLKPPLWRN---SSFCPLE---CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC 2244
Query: 952 TDGCVCPPGTVLLDERCVPPDLCPCR--HSGQWYLPNATIQEDCNV-CVCRGRQWHCTGQ 1008
+GC+C PG VL +++CVP C C+ H G L + + C CVC G C
Sbjct: 2245 AEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDF 2304
Query: 1009 R---------------------RSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL 1047
R +S +C G P Y+TFDG ++ G Y+L++ L
Sbjct: 2305 RCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVL 2364
Query: 1048 ------FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGP 1101
V +N + + + G V + G + VN + P
Sbjct: 2365 PEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNE 2423
Query: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQ 1161
L + G L L T L + + G ++ L + G V+GLCG++D + ND+
Sbjct: 2424 HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPS 2483
Query: 1162 GVLEPTAELAAHSWRL---SPLCPEPGDLP------------------HPCTMNTHRAGW 1200
G L +SW + L P +P C+ +
Sbjct: 2484 GALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNS 2543
Query: 1201 ARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECL-CSAIATYADECA 1257
+A C L P F CH V P+ E C+ D C + E L C ++ YA C
Sbjct: 2544 TQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
Query: 1258 RHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPE 1316
G + WR + LC C + C + C+ C C
Sbjct: 2603 EAGAALAGWRDRTLCESPC----LQNPC-------------QNDGQCREQGATFTCECEV 2645
Query: 1317 GTLLHGGACLEPASCP 1332
G GG C+EP P
Sbjct: 2646 G--YGGGLCMEPRDAP 2659
Score = 66.2 bits (160), Expect = 8e-10
Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 4/107 (3%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CP G C++ CP CS + C C + C C KG + CVP+G C
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 4118 DCTDAQGHSWAPGSQ--HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160
CTD G G + ++ C C+C ++C C P C
Sbjct: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
Score = 63.5 bits (153), Expect = 5e-09
Identities = 37/96 (38%), Positives = 43/96 (44%), Gaps = 19/96 (19%)
Query: 2626 LCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCL------- 2678
LC K PCP +C + CS CVE C C PG +L C+P S+C CL
Sbjct: 1434 LCAK----PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYF 1489
Query: 2679 -VGEELKWPGVSFLLGNCSQCVCE-KGELLCQPGGC 2712
VGE PG L CVCE + CQP C
Sbjct: 1490 KVGERWYKPGCKEL------CVCESNNRIRCQPWRC 1519
Score = 61.6 bits (148), Expect = 2e-08
Identities = 41/138 (29%), Positives = 53/138 (38%), Gaps = 8/138 (5%)
Query: 4040 GAPCAGERHQARLC-NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQV---CQ 4095
GA C + + L N C CPA C C C DL C+ +V C
Sbjct: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR--CEGAKVPSACA 2245
Query: 4096 KGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQ--HQDACNNCSCQAGQLSCTAQP 4153
+GC C G + + CVP C C DA G S G C C G + C
Sbjct: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFR 2305
Query: 4154 CPPPTHCAWSHWSAWSPC 4171
CP +HC + ++ S C
Sbjct: 2306 CPSGSHCQLTSDNSNSNC 2323
Score = 60.5 bits (145), Expect = 4e-08
Identities = 48/173 (27%), Positives = 66/173 (38%), Gaps = 35/173 (20%)
Query: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGC 4853
A CQ+Q + N CP ECP + C SC CW L + P C GC
Sbjct: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGC 2248
Query: 4854 GCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPG-TVLTRNCT-RCVCHG 4911
C G +L CVP + C C + +P G + ++ CT +CVC G
Sbjct: 2249 ICQPGYVLSEDKCVPRSQCGCK------------DAHGGSIPLGKSWVSSGCTEKCVCTG 2296
Query: 4912 GAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGC 4964
GA C D + P G Q + + + SNC S ++ C
Sbjct: 2297 GAIQCG--DFRCPSGSHCQ----------------LTSDNSNSNCVSDKSEQC 2331
Score = 59.7 bits (143), Expect = 7e-08
Identities = 30/80 (37%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
CP SC P+ SC C EGC C PG L D C+ S C C + PG + N
Sbjct: 1055 CPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112
Query: 2695 CSQ-CVCEKGELL-CQPGGC 2712
C++ C C G + CQ C
Sbjct: 1113 CTEHCRCWPGSRVECQISQC 1132
Score = 58.5 bits (140), Expect = 2e-07
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 15/113 (13%)
Query: 2878 NTQPCTAQCPE-----NMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGL 2932
N+ C +CP N L + C G C G + CA GC C PG
Sbjct: 2203 NSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCE--------GAKVPSACAEGCICQPGY 2254
Query: 2933 FLHNASCLPRSQCPCQ-LHGQLYASGAMARLDSC-NNCTCVSGKMACTSERCP 2983
L C+PRSQC C+ HG G C C C G + C RCP
Sbjct: 2255 VLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
Score = 58.5 bits (140), Expect = 2e-07
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 2632 VPPCPPSCLDPKANRSCSGH-----CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWP 2686
+P C PSC D + C G C EGC C PG +L + +C+P S+C C P
Sbjct: 2221 LPSCSPSCWD--LDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIP 2278
Query: 2687 -GVSFLLGNCSQ-CVCEKGELLCQPGGCP 2713
G S++ C++ CVC G + C CP
Sbjct: 2279 LGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
Score = 58.2 bits (139), Expect = 2e-07
Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 12/131 (9%)
Query: 2857 CSSLAPGDTTCPGP-HSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
C+ ++ TTC H+ C CP N + + PCP C + G
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK------PCPDTCHSGFSG 1449
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLH--GQLYASGAMARLDSCNN-CTCVS 2972
+ C+ C C C PG L C+PRSQC C LH G + G C C C S
Sbjct: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCES 1508
Query: 2973 -GKMACTSERC 2982
++ C RC
Sbjct: 1509 NNRIRCQPWRC 1519
Score = 57.4 bits (137), Expect = 4e-07
Identities = 59/202 (29%), Positives = 74/202 (36%), Gaps = 38/202 (18%)
Query: 3237 PEAEEEPCLLQG-----CDR---AGGWG--------PWGPWSHCSRSCGGGLRSRTRACD 3280
PE+ E C L G C A W P GP+S C + +S +C
Sbjct: 1712 PESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPP--QSSFASCV 1769
Query: 3281 QPPPQGLGD---YCEGPRAQGEVC-QALPCPV----TNCT--AIEGAEYSPCGPPCPRSC 3330
GD C +A +C QA P T C G+ YSPC PCP +C
Sbjct: 1770 HGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
Query: 3331 DDLVH---C--VWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP 3385
+ + C C C C G +LS G CV G C C D G H G R
Sbjct: 1830 SSINNPRDCPKALPCAESCECQKGHILS--GTSCVPLGQCGCTD-PAGSYHPVGERWYTE 1886
Query: 3386 DGCNH-CTC-LEGRLNCTDLPC 3405
+ C CTC + + C C
Sbjct: 1887 NTCTRLCTCSVHNNITCFQSTC 1908
Score = 57.0 bits (136), Expect = 5e-07
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 3/120 (2%)
Query: 4759 PHQEC-PVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCP- 4816
P +C V+ P S+++SC G + C A AQ + N CP
Sbjct: 1751 PFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPM 1810
Query: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQE-PCQPGCGCPGGQLLHNGTCVPPTACPCT 4875
CPPG S C++ CP C + C + PC C C G +L +CVP C CT
Sbjct: 1811 RCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCT 1870
Score = 53.9 bits (128), Expect = 4e-06
Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 25/134 (18%)
Query: 3291 CEGPRAQGEVCQALP-----------CPVTNCTAIEGAEYSPCGPPCPRSCDDL------ 3333
C+ +A G CQ+ CP+ C A + Y+ C P C SC DL
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPL-ECPAY--SSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 3334 VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CT 3392
C GC C PG VLS + CV C C D G P + GC C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDK--CVPRSQCGCKDAHGGS--IPLGKSWVSSGCTEKCV 2293
Query: 3393 CLEGRLNCTDLPCP 3406
C G + C D CP
Sbjct: 2294 CTGGAIQCGDFRCP 2307
Score = 53.1 bits (126), Expect = 7e-06
Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 13/117 (11%)
Query: 3090 CPRDKQWLDCAQGPASCAELSAPRGT-NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
CP + ++ CA PASC +PR + C GC C G L +N C+ C C +
Sbjct: 1044 CPPNARYESCAC-PASC---KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 3149 HLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCH 3205
Y PG+ P NC+ +C WP + E S + C G CH
Sbjct: 1100 DYYEPGAEWFSP--NCT------EHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
Score = 53.1 bits (126), Expect = 7e-06
Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 18/114 (15%)
Query: 4660 NGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGR 4716
N CP EC A + +C C SC DL R + + P C GC C PG ++ + +
Sbjct: 2203 NSSFCPLECPAYSSY--TNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK 2260
Query: 4717 CVPISSCRC-----GLPSANASWELAPAQAVQLDC-QNCTCVNESLVCPHQECP 4764
CVP S C C G SW V C + C C ++ C CP
Sbjct: 2261 CVPRSQCGCKDAHGGSIPLGKSW-------VSSGCTEKCVCTGGAIQCGDFRCP 2307
Score = 52.4 bits (124), Expect = 1e-05
Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 36/211 (17%)
Query: 4890 QAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNA 4949
Q+Q L P L RN + C A+S S +C L C +C +++
Sbjct: 2192 QSQGLKPP--LWRNSSFCPLECPAYS-SYTNC---------------LPSCSPSCWDLDG 2233
Query: 4950 TKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP-GSEWQEA--CESC 5006
+ SA A GC+CQPG+ S+ CVP C C +P G W + E C
Sbjct: 2234 RCEGAKVPSACAEGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKC 2292
Query: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFT-KG 5065
+C G C C G L + +C ++S C + + R T G
Sbjct: 2293 VCTGG----AIQCGDFRCPSGSHCQLTSDNSNSNC----VSDKSEQCSVYGDPRYLTFDG 2344
Query: 5066 TCYLDQVEVSYCSGYCPSSTHVMPE--EPYL 5094
Y Q ++Y + V+PE EP L
Sbjct: 2345 FSYRLQGRMTY---VLIKTVDVLPEGVEPLL 2372
Score = 52.0 bits (123), Expect = 2e-05
Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 9/102 (8%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481
+C P ++ C PC C + S C D C C C G + CIP +C C
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPRSQCGCL 1482
Query: 4482 HTSAAGAGMTLAPGDR-LQLGCKE-CECR-RGELHCTSQGCQ 4520
H AG G+R + GCKE C C + C C+
Sbjct: 1483 HP----AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCR 1520
Score = 51.2 bits (121), Expect = 3e-05
Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 8/91 (8%)
Query: 3317 AEYSPCGPPCPRSCDD-LVHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQR 3375
A Y C CP SC C C+ GC C PG + S N C+Q C+C
Sbjct: 1048 ARYESCA--CPASCKSPRPSCGPLCREGCVCNPGFLFSDNH--CIQASSCNC--FYNNDY 1101
Query: 3376 HHPGARLARPDGCNHCTCLEG-RLNCTDLPC 3405
+ PGA P+ HC C G R+ C C
Sbjct: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
Score = 50.4 bits (119), Expect = 4e-05
Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 12/102 (11%)
Query: 2883 TAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPR 2942
T +CP N + S CP C + P C C GC C PG + C+
Sbjct: 1041 TERCPPNARYESCA--------CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQA 1090
Query: 2943 SQCPCQLHGQLYASGAMARLDSC-NNCTCVSG-KMACTSERC 2982
S C C + Y GA +C +C C G ++ C +C
Sbjct: 1091 SSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
Score = 50.4 bits (119), Expect = 4e-05
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Query: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD 3576
P N T C C G S PC PCP +C ++ C P ++ C +C C G +
Sbjct: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDC-PKALPCAESCECQKGHILSG 1858
Query: 3577 GLCVPPAHCRCQYQPGA 3593
CVP C C G+
Sbjct: 1859 TSCVPLGQCGCTDPAGS 1875
Score = 49.3 bits (116), Expect = 1e-04
Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 5/109 (4%)
Query: 4055 PMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPI 4114
P C CP + CA CP C G+ C D C + C C G + C+P
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPR 1476
Query: 4115 GHCDCTDAQGHSWAPGSQ-HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160
C C G + G + ++ C C C++ ++ C C C
Sbjct: 1477 SQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFC 1525
Score = 48.1 bits (113), Expect = 2e-04
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 3317 AEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTG 3373
++YS C PCP +C + C RC C C PG VLS G C+ C CL G
Sbjct: 1430 SKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLS--GLECIPRSQCGCLH-PAG 1486
Query: 3374 QRHHPGARLARPDGCNH-CTC-LEGRLNCTDLPC 3405
G R +P GC C C R+ C C
Sbjct: 1487 SYFKVGERWYKP-GCKELCVCESNNRIRCQPWRC 1519
Score = 48.1 bits (113), Expect = 2e-04
Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCA-PCPLTCDDISGQ 1834
C S Q CA G + R CP P ++ + PC+ PCP TC I+
Sbjct: 1783 CRSLQAYASLCAQA-GQAPAWRNRTFCPMRCPPGSS------YSPCSSPCPDTCSSINNP 1835
Query: 1835 VTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWP-GQRIKAD---CQLC 1890
CP PC + C C +G +L CV QC C Y P G+R + +LC
Sbjct: 1836 RDCPKALPC-AESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
Query: 1891 IC 1892
C
Sbjct: 1894 TC 1895
Score = 47.8 bits (112), Expect = 3e-04
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
C P + C SPC C++ + + C PC C C KG + C+P +C C
Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC-- 1869
Query: 4483 TSAAGA 4488
T AG+
Sbjct: 1870 TDPAGS 1875
Score = 46.2 bits (108), Expect = 8e-04
Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 4678 CANQCPHSCADLWDRVQCLQG-PCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWEL 4736
C++ CP +C+ + + C + PC C C G ++ CVP+ C C P A + +
Sbjct: 1821 CSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP-AGSYHPV 1879
Query: 4737 APAQAVQLDCQN-CTC-VNESLVCPHQEC 4763
+ C CTC V+ ++ C C
Sbjct: 1880 GERWYTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 45.8 bits (107), Expect = 0.001
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 4/101 (3%)
Query: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
P CP + ++ CA+ P +C + + C C C G +L C+P C C
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCL 1482
Query: 3146 H-EGHLYPPGSTVVRP-C-ENCSCVSGLIANCSSWPCAEGE 3183
H G + G +P C E C C S C W C E
Sbjct: 1483 HPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQE 1523
Score = 44.7 bits (104), Expect = 0.002
Identities = 49/209 (23%), Positives = 69/209 (33%), Gaps = 30/209 (14%)
Query: 2778 WTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWA 2837
W S C GG P + + + + +C + P S VP
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADA-WNKNCAILINPQGPFSQCHQVVP------- 1760
Query: 2838 PWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRS 2894
P S+ ++ G T+G + C SL + C N C +CP +
Sbjct: 1761 PQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSP 1820
Query: 2895 AEQCHQEGGPCPRLCLTQGPGIECTGF--CAPGCTCPPGLFLHNASCLPRSQCPC----- 2947
PCP C + +C CA C C G L SC+P QC C
Sbjct: 1821 CSS------PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
Query: 2948 ---QLHGQLYASGAMARLDSC---NNCTC 2970
+ + Y RL +C NN TC
Sbjct: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITC 1903
Score = 43.9 bits (102), Expect = 0.004
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
CP CPP S CA CP C G C + C C C G +L C+P + C
Sbjct: 1422 CPMACPPNSKYSLCAKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRSQCG 1480
Query: 4874 C 4874
C
Sbjct: 1481 C 1481
Score = 43.9 bits (102), Expect = 0.004
Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 23/129 (17%)
Query: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSV--GCQPTCGCPLGQLS 3574
P NS+ C +C S C C SC DL C+ V C C C G +
Sbjct: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVL 2256
Query: 3575 QDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGIL 3634
+ CVP + C C+ G IP + SW V +G + C C G +
Sbjct: 2257 SEDKCVPRSQCGCKDAHGG-SIPLGK---------SW-------VSSGCTEKCVCTGGAI 2299
Query: 3635 QCQEVPDCP 3643
QC + CP
Sbjct: 2300 QCGDF-RCP 2307
Score = 43.9 bits (102), Expect = 0.004
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 8/103 (7%)
Query: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAP---RGTNQTCHPGCHCPSGMLLLNNVCVPTQDC 3142
P CP + +C + SC +L C GC C G +L + CVP C
Sbjct: 2208 PLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQC 2267
Query: 3143 PC--AHEGHLYPPGSTVVRPC-ENCSCVSGLIANCSSWPCAEG 3182
C AH G + S V C E C C G I C + C G
Sbjct: 2268 GCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAI-QCGDFRCPSG 2309
Score = 43.5 bits (101), Expect = 0.005
Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 20/146 (13%)
Query: 3059 GYRNRTRGSSRSLMEFSTCGLQPCAGPV-------PGMCPRDKQWLDCAQG-PASCAELS 3110
G + T RSL +++ Q P P CP + C+ P +C+ ++
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
Query: 3111 APRGTNQT--CHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPP-------GSTVVRPC 3161
PR + C C C G +L CVP C C Y P +T R C
Sbjct: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
Query: 3162 ENCSCVSGLIANCSSWPCAEGEPTWS 3187
CS + + C C + W+
Sbjct: 1894 -TCSVHNNI--TCFQSTCKPNQICWA 1916
Score = 42.7 bits (99), Expect = 0.009
Identities = 22/45 (48%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 4682 CPHSCADLWDRVQCLQGP-CRPGCRCPPGQLVQDGRCVPISSCRC 4725
CP SC R C GP CR GC C PG L D C+ SSC C
Sbjct: 1055 CPASCKS--PRPSC--GPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
Score = 42.7 bits (99), Expect = 0.009
Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 2634 PCPPSCLDPKANRSCSGH--CVEGCRCPPGLLLHDTRCLPLSECPC 2677
PCP +C R C C E C C G +L T C+PL +C C
Sbjct: 1824 PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
Score = 42.0 bits (97), Expect = 0.016
Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTD 4121
CP +CA CP C + +C++GC C G L D C+ C+C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSC----GPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
Query: 4122 AQGHSWAPGSQ--HQDACNNCSCQAG-QLSCTAQPCPPPTHC 4160
+ + PG++ + +C C G ++ C C T C
Sbjct: 1098 NNDY-YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
Score = 42.0 bits (97), Expect = 0.016
Identities = 28/114 (24%), Positives = 41/114 (35%), Gaps = 26/114 (22%)
Query: 4924 PPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
PP ++ A C +C + +C GCVC PG S C+
Sbjct: 1045 PPNARYESCA------CPASC-----KSPRPSCGPLCREGCVCNPGFLFSD-NHCIQASS 1092
Query: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSC 5037
C C++ + PG+EW P CT+HC C G + + C
Sbjct: 1093 CNCFYNNDYYEPGAEWFS-----------PNCTEHC---RCWPGSRVECQISQC 1132
Score = 40.8 bits (94), Expect = 0.035
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 4648 GGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCP 4707
G +PW + CP ++ ++L CA CP +C + + C C C C
Sbjct: 1410 GHAVKPWREPHF----CPMACPPNSKYSL-CAKPCPDTCHSGFSGMFC-SDRCVEACECN 1463
Query: 4708 PGQLVQDGRCVPISSCRCGLPSAN 4731
PG ++ C+P S C C P+ +
Sbjct: 1464 PGFVLSGLECIPRSQCGCLHPAGS 1487
Score = 38.5 bits (88), Expect = 0.17
Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 22/107 (20%)
Query: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQH 4877
CPP +CA CP C +P + C+ GC C G L + C+ ++C C +
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCT-RCVCHGGAFSCSLVDCQV 4923
+ + E A+ P NCT C C G S V+CQ+
Sbjct: 1099 NDYY------EPGAEWFSP------NCTEHCRCWPG----SRVECQI 1129
Score = 37.7 bits (86), Expect = 0.30
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 6/69 (8%)
Query: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPP 4475
S S + C P + +C P + C + C P C+ GC C G L CI
Sbjct: 1037 SRSSTERCPPNARYESCACPAS--CKS--PRPSCG--PLCREGCVCNPGFLFSDNHCIQA 1090
Query: 4476 EECNCWHTS 4484
CNC++ +
Sbjct: 1091 SSCNCFYNN 1099
Score = 37.4 bits (85), Expect = 0.39
Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 5/109 (4%)
Query: 3485 DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPR 3544
DMC Q + C+ T C +P +E C C +PCP
Sbjct: 1384 DMCGFQGLQHLLCTHMSTMT--TTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPD 1441
Query: 3545 SCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGA 3593
+C G C S C C C G + C+P + C C + G+
Sbjct: 1442 TCHSGFSGMFC---SDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGS 1487
Score = 37.4 bits (85), Expect = 0.39
Identities = 48/164 (29%), Positives = 63/164 (38%), Gaps = 22/164 (13%)
Query: 1883 IKADCQLCICQDGRPRRCRLNPDCAVDCG-WSSWSPWAKCLGPCGSQSIQWSFRSSNNPR 1941
++A LC Q G+ R C + C SS+SP C PC + S NNPR
Sbjct: 1786 LQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSP---CSSPCPD-----TCSSINNPR 1836
Query: 1942 PSGRGRQC-------RGIHRKARRCQTEPCEGC-EHQGQVHRVGERWH-GGPC-RVCQCL 1991
+ C +G C GC + G H VGERW+ C R+C C
Sbjct: 1837 DCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
Query: 1992 --HNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTV 2033
+N+T S P C L+ C LPGE+ V
Sbjct: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYV 1940
Score = 36.6 bits (83), Expect = 0.66
Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 4455 CQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKE-CECRRGELH 4513
C GC C G + C+P +C C A G + L + GC E C C G +
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGK-SWVSSGCTEKCVCTGGAIQ 2300
Query: 4514 CTSQGC 4519
C C
Sbjct: 2301 CGDFRC 2306
Score = 36.2 bits (82), Expect = 0.87
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 7/76 (9%)
Query: 4956 CSSARASGCVCQPGHFRSQAGPCVPEDHCECWH-LGRPHLPGSEW-QEAC-ESCLCLSGR 5012
CS C C PG S C+P C C H G G W + C E C+C S
Sbjct: 1452 CSDRCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNN 1510
Query: 5013 PVCTQHCSPLTCAQGE 5028
+ C P C E
Sbjct: 1511 RI---RCQPWRCRAQE 1523
Score = 35.4 bits (80), Expect = 1.5
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 10/57 (17%)
Query: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QYQPGA 3593
CP SC+ SP C P C+ C C G L D C+ + C C Y+PGA
Sbjct: 1055 CPASCK--SPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGA 1106
Score = 35.4 bits (80), Expect = 1.5
Identities = 29/115 (25%), Positives = 39/115 (33%), Gaps = 22/115 (19%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSE-GCEEGCHCPEGTFQHRLACVQ--ECPC 3753
CP G Y C CP +C+ + C C E C C +G +CV +C C
Sbjct: 1812 CPPGSSYSPCS--SPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
Query: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCA-HGKLSCSLDDC 3807
DP P E T T C+C+ H ++C C
Sbjct: 1870 T--------------DPAGSYHPVGE--RWYTENTCTRLCTCSVHNNITCFQSTC 1908
Score = 35.0 bits (79), Expect = 1.9
Identities = 35/142 (24%), Positives = 49/142 (34%), Gaps = 27/142 (19%)
Query: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
GP+E C + S C C Q C+ T C++AG
Sbjct: 1363 GPFETCLLHVKAASFFDS--CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPH 1420
Query: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--Q 3749
CP Y C + CP +C + C S+ C E C C G L C+
Sbjct: 1421 FCPMACPPNSKYSLC--AKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRS 1477
Query: 3750 ECPCVLTAWLLQELGATIGDPG 3771
+C C+ A ++G PG
Sbjct: 1478 QCGCLHPAGSYFKVGERWYKPG 1499
Score = 34.7 bits (78), Expect = 2.5
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 26/140 (18%)
Query: 4130 GSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSH----------WSAWSPCSHSCGPRG 4179
G +Q C + QA +C +Q PP W + +S+++ C SC P
Sbjct: 2174 GGLYQALCQ--ALQAFGATCQSQGLKPPL---WRNSSFCPLECPAYSSYTNCLPSCSPSC 2228
Query: 4180 QQSRFRSSTSGSWAPECREEQSQSQP---CPQPSCPPLCLQGTR-----SRTLGDSWLQG 4231
R G+ P E QP + C P G + S LG SW+
Sbjct: 2229 WDLDGRCE--GAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS 2286
Query: 4232 EC-QRCSCTPEGVICEDTEC 4250
C ++C CT + C D C
Sbjct: 2287 GCTEKCVCTGGAIQCGDFRC 2306
Score = 33.5 bits (75), Expect = 5.6
Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 36/115 (31%)
Query: 1795 STRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQ 1854
S T+ CP PNA ++ CA CP +C S + +C P GC C G
Sbjct: 1037 SRSSTERCP----PNAR------YESCA-CPASCK--SPRPSCGP---LCREGCVCNPG- 1079
Query: 1855 VLGSEGWCVWPRQCPCLVDGARY-----------------WPGQRIKADCQLCIC 1892
L S+ C+ C C + Y WPG R+ +CQ+ C
Sbjct: 1080 FLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRV--ECQISQC 1132
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 255 bits (651), Expect = 9e-67
Identities = 206/666 (30%), Positives = 270/666 (40%), Gaps = 118/666 (17%)
Query: 783 CLAAVCGCDPGSDCLCPVLSAYAR--RCAQEG-------ASPPW----RNQTLCP-VMCP 828
C A+C C CPV + R Q+G S W Q C + CP
Sbjct: 816 CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCP 875
Query: 829 G------GQEYRECAPACGQHCGKPEDCGELG------SCVAGCNCPLGLLWDPEGQCV- 875
E C P C E+ E S + C C G++ QC+
Sbjct: 876 PLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCIS 935
Query: 876 --------PPSLCP----CQLGARRYAPGSATMK---ECNRCICQERG----LWNCTARH 916
P CP C+ R+Y PG + C CIC+ + C R
Sbjct: 936 SCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQ 995
Query: 917 CPSQAFCPRELVYAPGA--CLLTCDSPSANHS-----CPAGSTDGC-------------- 955
CPS CP + PG C TC +N S D C
Sbjct: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
Query: 956 -VCPPGTVLLDERCVPPDLC---------PCRHSGQWYLPNATIQED-CNVCVCRGRQWH 1004
CP + L ER PP C C H G+ D C C C
Sbjct: 1056 QACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVR 1115
Query: 1005 CTGQR-------------------------RSGRCQASGAPHYVTFDGLAFTYPGACEYL 1039
C QR R C A G PHY TFDG + G+C Y+
Sbjct: 1116 CQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYV 1175
Query: 1040 LVREA-SGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVY 1098
L ++ SG F+V N G SG+ T+ +AV L V +L+ AVTV+G V P +
Sbjct: 1176 LAKDCHSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQ 1235
Query: 1099 TGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLR 1158
P L + G ++L GL +LWDG ++V V + ++GR GLCG+F+G A +DL+
Sbjct: 1236 E-PLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQ 1294
Query: 1159 SRQGVLEPTAELAAHSWRLSP-LCP----EPGDLPHPCTMNTHRA-GWARARCGALLQPL 1212
+G+L P+ +SW++S L P G PC +RA A ARCG L
Sbjct: 1295 GPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSP 1354
Query: 1213 FTLCHAEVPPQQHYEWCLYDACGCDSGGDCE-CLCSAIATYADECARHGHHVRWRSQELC 1271
F+ CHA VPP+ + C+YD C C G + CLC A+ YA C + G WR LC
Sbjct: 1355 FSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLC 1414
Query: 1272 SLQC--EGGQVYEACGPTCPPTCHEQH---PEPGWHCQVVACVEGCFCPEGTLLHGGACL 1326
+ C E G V++ CGP CP TC QH E HC V CV GC CP G + H C+
Sbjct: 1415 VVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC-VRPCVPGCQCPAGLVEHEAHCI 1473
Query: 1327 EPASCP 1332
P +CP
Sbjct: 1474 PPEACP 1479
Score = 203 bits (516), Expect = 4e-51
Identities = 148/443 (33%), Positives = 195/443 (44%), Gaps = 50/443 (11%)
Query: 466 ERLCPGGQLYSDCVSLCP----PSCEAVGQGEEESCRE----ECVSGCECPRGLFWNGTL 517
E CP + ++ S CP P+ V QG E + E + + C C G T+
Sbjct: 1060 ELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAG-----TV 1114
Query: 518 CVPAAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDG 577
+ C C P + C C+ R PA C GD HY TFDG
Sbjct: 1115 RCQSQRCSPLSCGPDKAPALSPGSCCPRCLPR-----------PASCMAFGDPHYRTFDG 1163
Query: 578 RSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAG----SCLHAISVSLEDTHIQLRDS 633
R F G C Y L +D G + + + D G + ++V L D ++L
Sbjct: 1164 RLLHFQGS--CSYVLAKDCHSGDFSVHVTND--DRGRSGVAWTQEVAVLLGDMAVRLLQD 1219
Query: 634 GAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQV 693
GAV V+G V LP++ L V +L PG QVLW V +++ + +
Sbjct: 1220 GAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVE-VSVPGSYQGRT 1278
Query: 694 QGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---KGRCPSEDSALLSPCTTHSQ 750
GLCG F QDD P G + S AAF + +QV+ GR P + PC
Sbjct: 1279 CGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR-PCSAGREVDPCRAAGY 1337
Query: 751 R-HAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSD---CLCPVLSAYAR 806
R A A C +L SS F CH +V EPF+ C+ +C C PGS CLC L AYA
Sbjct: 1338 RARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYAS 1397
Query: 807 RCAQEGASPPWRNQTLCPVMCP--GGQEYRECAPACGQHC-GKPEDCGELGS-----CVA 858
C Q G +P WR TLC V CP G + EC P C + C + GEL + CV
Sbjct: 1398 HCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP 1457
Query: 859 GCNCPLGLLWDPEGQCVPPSLCP 881
GC CP GL+ + E C+PP CP
Sbjct: 1458 GCQCPAGLV-EHEAHCIPPEACP 1479
Score = 156 bits (394), Expect = 6e-37
Identities = 142/485 (29%), Positives = 203/485 (41%), Gaps = 73/485 (15%)
Query: 94 CCPGWGGA--HCTEAL--AKASPEGHCFAM------WQCQLQA--------GSANASAGS 135
CCP A +C+E L ++ +P C+ W C QA + GS
Sbjct: 1015 CCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGS 1074
Query: 136 LEECCARPW------------GQSWWDGSSQAC-------RSCSSRHLP---GSASSPAL 173
C P G+ W + +C R S R P G +PAL
Sbjct: 1075 CCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPAL 1134
Query: 174 LQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVH 232
+ G + A+C ++ HYRTFDGR HF G C+Y+LA S ++VH
Sbjct: 1135 ------SPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH 1188
Query: 233 LTPGDRCPQPGHCQR---VTMGPEEV-LIQAGNVSVKGQLV--PEGQSWLLHGLSLQWLG 286
+T DR + V +G V L+Q G V+V G V P Q LL+ ++ G
Sbjct: 1189 VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY---VELRG 1245
Query: 287 DWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAA 346
++L G+ V D + +SV G+T GLCG +NG+ +DD P G L A
Sbjct: 1246 HTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEA 1305
Query: 347 TFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGH-LRAEAQDVCHQLLEGPFGQC 405
FGNSW++ + + + C +D G+ R EA C L PF +C
Sbjct: 1306 AFGNSWQVS-------EGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRC 1358
Query: 406 HAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFC 465
HA V P + AC++ CA G G +C +Y C + + WR P C
Sbjct: 1359 HAVVPPEPFFAACVYDLCA---CGPGSSA-DACLCDALEAYASHCRQAGVTPTWRGPTLC 1414
Query: 466 ERLCP--GGQLYSDCVSLCPPSC--EAVGQGE-EESCREECVSGCECPRGLFWNGTLCVP 520
CP G ++ +C CP +C + + GE C CV GC+CP GL + C+P
Sbjct: 1415 VVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIP 1474
Query: 521 AAHCP 525
CP
Sbjct: 1475 PEACP 1479
Score = 155 bits (393), Expect = 7e-37
Identities = 359/1512 (23%), Positives = 459/1512 (30%), Gaps = 408/1512 (26%)
Query: 3236 GPEAEEEPCLLQGC-DRAGGWGPWGPWSHCSRSC-------GGGLRSRTRACDQPPPQGL 3287
G E + C C D A GP HC R C G G AC
Sbjct: 106 GARWEPDACTACVCQDGAAHCGPQAHLPHC-RGCSQNGQTYGNGETFSPDACTTCRCLTG 164
Query: 3288 GDYCEGPRAQGEVCQALPCPVTNCTAI----------EGAEYSPCGPPCP--RSCDDLVH 3335
C+GP C P C I G E++ G PC R + +
Sbjct: 165 AVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQ 224
Query: 3336 CVWRCQPGCYCP-PGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCL 3394
C R + CP P + L G C C L G+ H G + D C+HC C
Sbjct: 225 CRQR-ECASLCPYPARPLP--GTCCPVCDGC----FLNGREHRSGEPVGSGDPCSHCRCA 277
Query: 3395 EGRLNCTDLPCP---------VPGGWCPWSEWT-------MCSQPCRGQTRSRSRACACP 3438
G + C LPCP +PG CP + + R Q R C+C
Sbjct: 278 NGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSC- 336
Query: 3439 TPQHGGAPCTGEAGEAGAQHQ-------------REACPSYATCPVDG-------AWGPW 3478
+AGE + Q R+ CP+ C +DG W P
Sbjct: 337 -----------QAGEVSCEEQECPVTPCALPASGRQLCPA---CELDGEEFAEGVQWEPD 382
Query: 3479 GPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRP--CQENSTQCT----DCGGG 3532
G PC C+ Q + C P P P H P C + CT G
Sbjct: 383 G--RPCTACVCQDGVPK-CGAVLCP----PAPCQHPTQPPGACCPSCDSCTYHSQVYANG 435
Query: 3533 QSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQ----PTCGCPLGQLSQDGLCVPPAHCRCQ 3588
Q+ PC +C CQ G+V C P C Q S G C P RC
Sbjct: 436 QNFTDADSPC-HACH-------CQDGTVTCSLVDCPPTTCARPQ-SGPGQCCP----RC- 481
Query: 3589 YQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVP-------- 3640
P I E + G FS P + PC C C G CQ P
Sbjct: 482 --PDC--ILEEEVFVDGESFS-----HPRD----PCQECRCQEGHAHCQPRPCPRAPCAH 528
Query: 3641 -----DCPDPGVWSSWG------------PWEDCSV--SCGGGEQLRSRRCARPPCPGPA 3681
CP+ ++G P + C + G Q +RRC PCP P
Sbjct: 529 PLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPV 588
Query: 3682 RQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEG--CEEGCHCPEG 3739
C Q AGCP +PG AH Q G C C C +G
Sbjct: 589 LLPGECCPQCPAPAGCP--------RPG------AAHARHQEYFSPPGDPCRR-CLCLDG 633
Query: 3740 TFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTL---RTSCGNCSCA 3796
+ ++C Q PC G L G E SG+ +C C C
Sbjct: 634 S----VSC-QRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCW 688
Query: 3797 HGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGG---LGTRTRSRQ-------------CV 3840
G +SC C A P+ G C C G LG S Q C+
Sbjct: 689 EGSVSCEPKACAPA---LCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCL 745
Query: 3841 LTMPTLSGQGCRGP--RQDLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTD 3898
T + C P L CP +G VT G + D
Sbjct: 746 GGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASG------------ETLPD 793
Query: 3899 PARPAWRSRTRLCLANCTMGD-PLQERPCNLPSCTE-------LPVC------------- 3937
P P L C G Q++PC C PVC
Sbjct: 794 PLDPT------CSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDG 847
Query: 3938 ---PGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGP-------GGHWCPNIL 3987
GP AG+C W C GQ +R PP P G CP
Sbjct: 848 EEFEGP---AGSCEWC----------RCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRC- 893
Query: 3988 TAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRS-------RSCSSPPSKNGG 4040
R C P G SRW P SC + + + SC+ P + G
Sbjct: 894 ------RGCLAHGEEHPEG-SRWVPPDSACSSCVCHEGVVTCARIQCISSCAQP--RQGP 944
Query: 4041 APCAGE----RHQAR------------------LCNPMP-------CE-------AGCPA 4064
C + H+ R +C P P C GCP
Sbjct: 945 HDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPP 1004
Query: 4065 GMEVVT----CANRCPRRCSDLQEGIV--------------CQD------DQVCQKGCRC 4100
+ C C S+ EG++ CQD Q C + C
Sbjct: 1005 SQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPE-LSC 1063
Query: 4101 PKGSLE-QDGGCVPIGHCDCTDA--QGHSWAPGSQHQ-DACNNCSCQAGQLSCTAQPCPP 4156
P G C P+ QG A G + D C +CSC AG + C +Q C
Sbjct: 1064 PLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRC-S 1122
Query: 4157 PTHCAWSHWSAWSP--CSHSCGPR----------------GQQSRFRSSTSGSWAPEC-- 4196
P C A SP C C PR G+ F+ S S A +C
Sbjct: 1123 PLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHS 1182
Query: 4197 --------REEQSQSQPC-PQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICED 4247
+++ +S Q L R G + G E ++ +
Sbjct: 1183 GDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVE 1242
Query: 4248 TE------CAVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPD-TQTR 4300
A P LW S VS G Q RT GP+
Sbjct: 1243 LRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLP 1302
Query: 4301 QQPCPGLLEACSWGPW--GPCS--RSCGPGLAS-----RSGSCPCLMAKADP--TCNSTF 4349
+ G S G W PCS R P A+ R + C + K+ P C++
Sbjct: 1303 SEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAV- 1361
Query: 4350 LHLDTQGCYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGH 4409
+ + ++ + C SS C C L + AS +AG T
Sbjct: 1362 --VPPEPFFAACVYDLCACGPGSSADACLCDAL-------EAYASHCRQAGVTPTWRGPT 1412
Query: 4410 FRPCLISNCSEDSCTPPFEFHACGSPCAGLCATH---LSHQLCQDLPPCQPGCYCPKGLL 4466
C++ E F F CG PC C L + PC PGC CP GL+
Sbjct: 1413 L--CVVGCPLERG----FVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLV 1466
Query: 4467 EQAGGCIPPEEC 4478
E CIPPE C
Sbjct: 1467 EHEAHCIPPEAC 1478
Score = 148 bits (373), Expect = 2e-34
Identities = 311/1325 (23%), Positives = 409/1325 (30%), Gaps = 394/1325 (29%)
Query: 2897 QCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCP----CQLHGQ 2952
+CH C L G C C G A C P++ P C +GQ
Sbjct: 88 ECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGA----AHCGPQAHLPHCRGCSQNGQ 143
Query: 2953 LYASGAMARLDSCNNCTCVSGKMAC----------------TSERCPVAC--GWSPW--- 2991
Y +G D+C C C++G + C E CP+ C G S W
Sbjct: 144 TYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGGSHWEHG 203
Query: 2992 TLWS-------LCSC-SCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPG 3043
W+ +C C ++ R+R A P A RP PG
Sbjct: 204 QEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPA------------------RPLPG-- 243
Query: 3044 GEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGP 3103
C C G + N S + PC+ CA G
Sbjct: 244 -------TCCPVCDGCFLNGREHRSGEPVGSG----DPCS------------HCRCANGS 280
Query: 3104 ASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCP----CAHEGHLYPPGSTVVR 3159
C L P + HPG +P Q CP C ++GH Y T
Sbjct: 281 VQCEPLPCPPVPCR--HPG-------------KIPGQCCPVCDGCEYQGHQYQSQETFRL 325
Query: 3160 P----CENCSCVSGLIA----NCSSWPCA--------------EGEP-----TWSP-WTP 3191
C CSC +G ++ C PCA +GE W P P
Sbjct: 326 QERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRP 385
Query: 3192 WSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDR 3251
+ C G +C AV AP P P C P + C
Sbjct: 386 CTACVCQDGVPKC----------GAVLCPPAPCQHPTQPPGACC-PSCDS--CTYHSQVY 432
Query: 3252 AGGWGPWGPWSHC-SRSCGGGLRSRTRAC---DQPPPQGLGDYCEGPRA-QGEVCQALP- 3305
A G S C + C G T C D PP C P++ G+ C P
Sbjct: 433 ANGQNFTDADSPCHACHCQDG----TVTCSLVDCPPTT-----CARPQSGPGQCCPRCPD 483
Query: 3306 CPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPG-CYCPPGQVLSSNGAICVQPGH 3364
C + ++G +S PC + C RCQ G +C P + A + PG
Sbjct: 484 CILEEEVFVDGESFSHPRDPC-QEC--------RCQEGHAHCQPRPCPRAPCAHPL-PGT 533
Query: 3365 C---SCLDLLTGQRHHP-GARLARP-DGCNHCTCLEGRL-----NCTDLPCP----VPGG 3410
C C G + +P GA P D C C CL G + C LPCP +PG
Sbjct: 534 CCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGE 593
Query: 3411 WCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCP 3470
CP C P CP P G A A+HQ P
Sbjct: 594 CCP-----QCPAP-----------AGCPRP-----------GAAHARHQEYFSP------ 620
Query: 3471 VDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCG 3530
P PC CL S +C R P P P P H + PC C C
Sbjct: 621 ---------PGDPCRRCLCLD-GSVSCQRLPCP----PAPCAHPRQGPC---CPSCDGCL 663
Query: 3531 GGQSLHPCGQ--PCPRSCQDLSPGSVCQPGSVGCQP-TCGCPLGQLSQDGLCVPPAHCRC 3587
G+ P P + L +C GSV C+P C L G C P C
Sbjct: 664 YQGKEFASGERFPSPTAACHL---CLCWEGSVSCEPKACAPALCPFPARGDCCPDCD-GC 719
Query: 3588 QYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGV 3647
+Y S S+ E +P E PC+ CTC+ G + C P C PG
Sbjct: 720 EY-------------LGESYLSNQEFPDPRE----PCNLCTCLGGFVTCGRRP-CEPPGC 761
Query: 3648 WSSWGPWEDCSVSCGG----------GEQL---------------RSRRCARPPCPG--- 3679
P C +C G GE L S RC + PCP
Sbjct: 762 SHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821
Query: 3680 PARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEG 3739
P C VC GR +++ + EG SC E C C G
Sbjct: 822 PHPSPGPCFCPVCHSC-LSQGREHQDGEEFEGPAGSC---------------EWCRCQAG 865
Query: 3740 TFQHRLACVQ-ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTL---RTSCGNCSC 3795
+++CV+ +CP + + E G+ L G+E G ++C +C C
Sbjct: 866 ----QVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVC 921
Query: 3796 AHGKLSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPR 3855
G ++C+ C + C PR
Sbjct: 922 HEGVVTCARIQCISS----------------------------------------CAQPR 941
Query: 3856 QDLECPSPDCPGA--EGSTVEPVTGLPGGWGPWSSWSPCSRSCTDP---ARPAWRSRTRL 3910
Q P C EG EP G PC +P P+ R R
Sbjct: 942 QGPHDCCPQCSDCEHEGRKYEPGESFQPG------ADPCEVCICEPQPEGPPSLRCHRRQ 995
Query: 3911 C--LANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCS----WTSWAPWEPCSRSCGV 3964
C L C P Q P C CP NCS + AP +PC +C
Sbjct: 996 CPSLVGC---PPSQLLPPGPQHC-----CPTCAEALSNCSEGLLGSELAPPDPC-YTCQC 1046
Query: 3965 GQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWC---DRSCG 4021
L ++ CP + ER CPV +P C R
Sbjct: 1047 QDLTWLCIHQA-------CPELSCPLSERHTPPGSCCPVCR-----APTQSCVHQGREVA 1094
Query: 4022 GGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRC-PRRCS 4080
G+ +C+S G C +R C+P+ C + +C RC PR S
Sbjct: 1095 SGERWTVDTCTSCSCMAGTVRCQSQR-----CSPLSCGPDKAPALSPGSCCPRCLPRPAS 1149
Query: 4081 DLQEG 4085
+ G
Sbjct: 1150 CMAFG 1154
Score = 146 bits (369), Expect = 5e-34
Identities = 391/1643 (23%), Positives = 511/1643 (31%), Gaps = 391/1643 (23%)
Query: 3427 QTRSRS-RACAC--PTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGA--WGPWGPW 3481
QTR R +C C +PQ G G A GA+ + +AC + C DGA GP
Sbjct: 78 QTRVRQLESCECHPASPQCWGL---GRAWPEGARWEPDACTA-CVCQ-DGAAHCGPQAHL 132
Query: 3482 SPCDMCL--------GQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQ-------- 3525
C C G++ AC+ G C G C E+ T
Sbjct: 133 PHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPIC 192
Query: 3526 CTDCGG----GQSLHPCGQPCPRSCQDLSPGSVCQPGSVGC-QPTCG--CPLGQLSQDGL 3578
CT+ G GQ G PC R C+ C G + C Q C CP G
Sbjct: 193 CTEGGSHWEHGQEWTTPGDPC-RICR-------CLEGHIQCRQRECASLCPYPARPLPGT 244
Query: 3579 CVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQE 3638
C P G N G S E + G+ PC +C C G +QC+
Sbjct: 245 CCPVCD----------GCFLN-----GREHRSGEPVGSGD----PCSHCRCANGSVQCEP 285
Query: 3639 VPDCPDPGVWSSWGPWEDCSVSCGG----GEQLRSRRCARPPCPGPARQSRTCSTQV--- 3691
+P P P P + C V C G G Q +S+ R G + CS Q
Sbjct: 286 LPCPPVPCRHPGKIPGQCCPV-CDGCEYQGHQYQSQETFRLQERGLCVR---CSCQAGEV 341
Query: 3692 -CREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCE--------EGCHCPEGTFQ 3742
C E CP + CP +C ++ F+EG + C C +G +
Sbjct: 342 SCEEQECPVTPCALPASGRQLCP-ACELDGEE---FAEGVQWEPDGRPCTACVCQDGVPK 397
Query: 3743 HRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTS---CGNCSCAHGK 3799
PC Q GA +GQ + C C C G
Sbjct: 398 CGAVLCPPAPCQHPT---QPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
Query: 3800 LSCSLDDCFEADGGFGPWSPWGPCSRSCGGLGTRT-RSRQCVL-----------TMPTLS 3847
++CSL DC P C+R G G R C+L + P
Sbjct: 455 VTCSLVDC-----------PPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDP 503
Query: 3848 GQGCRGPRQDLECPSPDCPGAEGSTVEPVTGLPG---GWGPWSSWSPCSRSCTDPARPAW 3904
Q CR C CP A + P T P G P P+ P
Sbjct: 504 CQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPC- 562
Query: 3905 RSRTRLCLANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGV 3964
RLC C G+ C C LP CP P G C AP C R G
Sbjct: 563 ----RLC--RCLSGNV----QCLARRCVPLP-CPEPVLLPGECCPQCPAP-AGCPRP-GA 609
Query: 3965 GQQRRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGG-- 4022
R + PPG C + + +R L P P R P C SC G
Sbjct: 610 AHARHQEYFSPPGDPCRRCLCLDGSVSCQR---LPCPPAPCAHPRQGP---CCPSCDGCL 663
Query: 4023 --GQSLRSRSCSSPPSK--------NGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCA 4072
G+ S P+ G C + LC P P C
Sbjct: 664 YQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALC-PFPARGDC---------- 712
Query: 4073 NRCPR--RCSDLQEGIVCQDD-----QVCQKGCRCPKGSLE------QDGGC----VPIG 4115
CP C L E + + + C C C G + + GC +P G
Sbjct: 713 --CPDCDGCEYLGESYLSNQEFPDPREPCNL-CTCLGGFVTCGRRPCEPPGCSHPLIPSG 769
Query: 4116 HCDCTDAQGHSW-----APGSQHQD----ACNNCSCQAGQLSCTAQPCPPPTHCAWSHWS 4166
HC C QG + A G D C+ C+CQ G + C +PCPP S
Sbjct: 770 HC-CPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGP 828
Query: 4167 AWSPCSHSCGPRGQQSRFRSSTSG-----SWAPECREEQSQSQPCPQPSCPPL------- 4214
+ P HSC +G++ + G W CR + Q C + CPPL
Sbjct: 829 CFCPVCHSCLSQGREHQDGEEFEGPAGSCEW---CRCQAGQVS-CVRLQCPPLPCKLQVT 884
Query: 4215 -----------CLQGTRSRTLGDSWLQGE--CQRCSCTPEGVICEDTECAVPEAWTLWSS 4261
CL G W+ + C C C V C +C A
Sbjct: 885 ERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGP 944
Query: 4262 WSDCPVSC-----------GGGNQVRTRACRAAA--PHHRSPPCLGPDTQTRQQPCPGLL 4308
CP G Q C P PP L + ++ CP L+
Sbjct: 945 HDCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSL----RCHRRQCPSLV 1000
Query: 4309 EA--CSWGPWGP--CSRSCGPGLASRS-GSCPCLMAKADP--TCNSTFLHLDTQGCYSGP 4361
P GP C +C L++ S G +A DP TC L T C
Sbjct: 1001 GCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDL---TWLCIHQA 1057
Query: 4362 CPE-ECVWSSWSSWTRCSCRVL--VQQRYRHQG-PASRGAR----AGAPCTRLDGHFRPC 4413
CPE C S + C V Q HQG + G R C+ + G R C
Sbjct: 1058 CPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVR-C 1116
Query: 4414 LISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCI 4473
CS SC P P PG CP+ C+
Sbjct: 1117 QSQRCSPLSCGP------------------------DKAPALSPGSCCPR--------CL 1144
Query: 4474 P-PEECNCW---HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTS--QGCQGLLPLSE 4527
P P C + H + G + K+C +H T+ +G G+
Sbjct: 1145 PRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSGVA---- 1200
Query: 4528 WSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGR 4587
W++ L ++ H P L PLL E H + L G
Sbjct: 1201 WTQEVAVLLGDMAVRLLQDGAVTVDGH----PVALPFLQEPLLYVELRGHTVILHAQPGL 1256
Query: 4588 P--WTGAPHL-CTAPLSQQ-RLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAE 4643
W G + + P S Q R C G Q L GP +P F W+ +E
Sbjct: 1257 QVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGP-EGLLLPSEAAFGNSWQVSE 1315
Query: 4644 ALCGGGCREPWAQESCNGG----PCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGP 4699
L W C+ G PC R +
Sbjct: 1316 GL--------WPGRPCSAGREVDPC---------------------------RAAGYRAR 1340
Query: 4700 CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCP 4759
RC G L + P S C +P P A CV + C
Sbjct: 1341 REANARC--GVL----KSSPFSRCHAVVPPE-------PFFAA--------CVYDLCAC- 1378
Query: 4760 HQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECP 4819
GP S+ +C +E + + GV P T C L+
Sbjct: 1379 -------GPGSSADACLCDA----LEAYASHCRQAGVTPTWRGPTLCVVGCPLER----- 1422
Query: 4820 PGQVLSACATSCPCLCW--HLQPGAI---CVQEPCQPGCGCPGGQLLHNGTCVPPTACP- 4873
G V C CP C+ H+ G + CV+ PC PGC CP G + H C+PP ACP
Sbjct: 1423 -GFVFDECGPPCPRTCFNQHIPLGELAAHCVR-PCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
Query: 4874 -CTQHSLPWGLTLTLEEQAQELP 4895
P G + + QE P
Sbjct: 1481 VLLTGDQPLGARPSPSREPQETP 1503
Score = 143 bits (361), Expect = 4e-33
Identities = 308/1264 (24%), Positives = 386/1264 (30%), Gaps = 340/1264 (26%)
Query: 3921 LQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRPPGPGG 3980
LQ R L SC P P C +W A WEP + + V Q GP
Sbjct: 77 LQTRVRQLESCECHPA--SPQCWGLGRAWPEGARWEPDACTACVCQDGAAHC----GPQA 130
Query: 3981 HWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGG 4040
H + R C G ++ G G++ +C++ G
Sbjct: 131 H-------------LPHCRGCSQNG------------QTYGNGETFSPDACTTCRCLTGA 165
Query: 4041 APCAG----ERHQARLCNPMPCEAGCPA-----------GMEVVTCANRCPRRCSDLQEG 4085
C G E + C P P E CP G E T + C R C L+
Sbjct: 166 VQCQGPSCSELNCLESCTP-PGEC-CPICCTEGGSHWEHGQEWTTPGDPC-RICRCLEGH 222
Query: 4086 IVCQDDQVCQKGCR--CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQ--HQDACNNCS 4141
I C+ Q+ C CP + G C P+ CD G G D C++C
Sbjct: 223 IQCR-----QRECASLCPYPARPLPGTCCPV--CDGCFLNGREHRSGEPVGSGDPCSHCR 275
Query: 4142 CQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQS 4201
C G + C PCPP PC H GQ
Sbjct: 276 CANGSVQCEPLPCPPV------------PCRHPGKIPGQ--------------------- 302
Query: 4202 QSQPCPQPSCPPLC----LQGTRSRTLGDSWLQ--GECQRCSCTPEGVICEDTECAVPEA 4255
C P+C QG + ++ LQ G C RCSC V CE+ EC V
Sbjct: 303 ---------CCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPC 353
Query: 4256 WTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGP 4315
S CP G + P R PC Q C +L C P
Sbjct: 354 ALPASGRQLCPACELDGEEFAEGV--QWEPDGR--PCTACVCQDGVPKCGAVL--C---P 404
Query: 4316 WGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWT 4375
PC P A C F D+ C++ C + V S
Sbjct: 405 PAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSP-CHACHCQDGTVTCSLVDCP 463
Query: 4376 RCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSP 4435
+C GP G C R C++ E+ F P
Sbjct: 464 PTTCA------RPQSGP-------GQCCPRCPD----CILE---EEVFVDGESFSHPRDP 503
Query: 4436 CAGLCATHLSHQLCQDLP----PCQ---PGCYCPKGLLEQA-GGCIPPEECNCWHTSAAG 4487
C C H CQ P PC PG CP A GG P + H S
Sbjct: 504 CQE-CRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDP- 561
Query: 4488 AGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPCLPPSALAPAS 4547
C+ C C G + C ++ C L C P P A P
Sbjct: 562 --------------CRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRP 607
Query: 4548 RTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCP 4607
A H SP P R LCLD + P AP + P
Sbjct: 608 GAAHARH----QEYFSPPGDPC------RRCLCLDGSVSCQRLPCP---PAPCAH----P 650
Query: 4608 DPGACPDSCQWSLW------------GPWSPCQVPCSGGFRLRWREAEALCGGGCREPWA 4655
G C SC L+ P + C + C L W + + C
Sbjct: 651 RQGPCCPSCDGCLYQGKEFASGERFPSPTAACHL-C-----LCWEGSVSCEPKACAPALC 704
Query: 4656 QESCNGGPCPECEAQDTVFTLDCANQ--------CPHSCADLWDRVQCLQGPCRP-GCRC 4706
G CP+C+ + + +NQ C + C L V C + PC P GC
Sbjct: 705 PFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPC-NLCTCLGGFVTCGRRPCEPPGCSH 763
Query: 4707 PPGQLVQDGRCVPI-SSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP- 4764
P L+ G C P CR AS E P + C CTC S+ C + CP
Sbjct: 764 P---LIPSGHCCPTCQGCRYH-GVTTASGETLP-DPLDPTCSLCTCQEGSMRCQKKPCPP 818
Query: 4765 VLGPWSAWSSCSAPCGGGTMERHRTCEGGP---GVA-----------------------P 4798
L P + C P + + R + G G A P
Sbjct: 819 ALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLP 878
Query: 4799 CQAQDTEQRQECNLQPCPEC-----------------PPGQVLSACATSCPC-----LCW 4836
C+ Q TE R C CP C PP SAC+ SC C C
Sbjct: 879 CKLQVTE-RGSC----CPRCRGCLAHGEEHPEGSRWVPPD---SACS-SCVCHEGVVTCA 929
Query: 4837 HLQPGAICVQEPCQPGCGCPG-------GQLLHNGTCVPPTACPCTQHSLPWGLTLTLEE 4889
+Q + C Q P CP G+ G P A PC + + E
Sbjct: 930 RIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCE---------VCICE 980
Query: 4890 QAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNA 4949
E PP C R C SLV C PP Q + PG C TC E
Sbjct: 981 PQPEGPPSL----RCHRRQCP------SLVGC--PPS---QLLPPGPQHCCP-TCAE--- 1021
Query: 4950 TKTQSNCSSARASG----------CVCQP-----------------GHFRSQAGPCVPED 4982
SNCS C CQ + G C P
Sbjct: 1022 --ALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVC 1079
Query: 4983 HC---ECWHLGRPHLPGSEWQ-EACESCLCLSGRPVC-TQHCSPLTCAQGEEMVLEPGSC 5037
C H GR G W + C SC C++G C +Q CSPL+C + L PGSC
Sbjct: 1080 RAPTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSC 1139
Query: 5038 CPSC 5041
CP C
Sbjct: 1140 CPRC 1143
Score = 142 bits (358), Expect = 9e-33
Identities = 268/1136 (23%), Positives = 354/1136 (31%), Gaps = 262/1136 (23%)
Query: 2667 TRCLPLSECPC------LVGEELKWP-GVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWS 2719
TR L C C G WP G + C+ CVC+ G C P
Sbjct: 79 TRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGP---------- 128
Query: 2720 AWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWT 2779
+ P R C + + P A C + QG P
Sbjct: 129 --QAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQG-------------PSC 173
Query: 2780 SWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPV-PSIWGLWAP 2838
S +C +SC PG C P C S W
Sbjct: 174 SELNCLESCTPPG----------------------------ECCPICCTEGGSHWEHGQE 205
Query: 2839 WSTCSAPC------DGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLF 2892
W+T PC +G IQ R R C+SL CP P C
Sbjct: 206 WTTPGDPCRICRCLEGHIQCRQRECASL------CPYPARPLPGTCCPVCDGCFLNGREH 259
Query: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCP----CQ 2948
RS E G PC C ++C CPP H +P CP C+
Sbjct: 260 RSGEPV-GSGDPCSH-CRCANGSVQCEPL-----PCPPVPCRHPGK-IPGQCCPVCDGCE 311
Query: 2949 LHGQLYASGAMARLDS---CNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGI 3005
G Y S RL C C+C +G+++C + CPV P + LC +C +
Sbjct: 312 YQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCP-ACELD- 369
Query: 3006 RRRFRAGT-----APPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGY 3060
F G P + P A C PC P G P C Y
Sbjct: 370 GEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSC--TY 427
Query: 3061 RNRTRGSSRSLMEFS-------------TCGL-----QPCAGPVPG---MCPRDKQWLDC 3099
++ + ++ + TC L CA P G CPR +
Sbjct: 428 HSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILE 487
Query: 3100 AQGPASCAELSAPRGTNQTC-----HPGCH---CPSGMLL--LNNVCVPTQDCPCAHEGH 3149
+ S PR Q C H C CP L C P CA G
Sbjct: 488 EEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGK 547
Query: 3150 LYPPGSTVVR---PCENCSCVSG----LIANCSSWPCAEGEPTWSPWTPWSQCSASCG-- 3200
YP G+ PC C C+SG L C PC EP P QC A G
Sbjct: 548 EYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCP--EPVLLPGECCPQCPAPAGCP 605
Query: 3201 -PARCH-RHRFCARSPS-------AVPSTVAPLPLPATPTPLCSGPEAEE-----EPCLL 3246
P H RH+ P + +V+ LP P P C+ P + CL
Sbjct: 606 RPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAP-CAHPRQGPCCPSCDGCLY 664
Query: 3247 QGCDRAGGWGPWGPWSHCSRSC--GGGLRSRTRACDQP--PPQGLGDY---CEGPRAQGE 3299
QG + A G P + C G + +AC P GD C+G GE
Sbjct: 665 QGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGE 724
Query: 3300 VC---QALPC---PVTNCTAIEG---AEYSPCGPP-CPRSCDDLVHCVWRCQ-------- 3341
Q P P CT + G PC PP C HC CQ
Sbjct: 725 SYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVT 784
Query: 3342 ------------PGCY---------------CPPGQVLSSNGAICVQPGHCSCLDLLTGQ 3374
P C CPP + C P SCL G+
Sbjct: 785 TASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLS--QGR 842
Query: 3375 RHHPGARLARPDG-CNHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRG------Q 3427
H G P G C C C G+++C L CP +E C CRG +
Sbjct: 843 EHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEE 902
Query: 3428 TRSRSR------ACACPTPQHGGAPCTG----EAGEAGAQHQREACPSYATCPVDG-AWG 3476
SR AC+ G C + Q + CP + C +G +
Sbjct: 903 HPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYE 962
Query: 3477 PWGPW----SPCDMCLGQ----------SHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
P + PC++C+ + HR + S P PG C E
Sbjct: 963 PGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEA 1022
Query: 3523 STQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQL-SQDGLCVP 3581
+ C++ G L P CQDL+ + Q C P CPL + + G C P
Sbjct: 1023 LSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQ----AC-PELSCPLSERHTPPGSCCP 1077
Query: 3582 PAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQ 3637
CR P + + + ++G R++ C +C+C+AG ++CQ
Sbjct: 1078 V--CRA---PTQSCVHQGREVASGERWT-----------VDTCTSCSCMAGTVRCQ 1117
Score = 111 bits (278), Expect = 2e-23
Identities = 221/916 (24%), Positives = 276/916 (30%), Gaps = 246/916 (26%)
Query: 4274 QVRTRACRAAAPHHRSPPCLG------------PDTQTRQQPCPGLLEACSWGPWG--PC 4319
Q R R + H SP C G PD T C A GP P
Sbjct: 78 QTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTA---CVCQDGAAHCGPQAHLPH 134
Query: 4320 SRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQG--CYSGPCPEECVWSSWSSWTRC 4377
R C G+ A TC + QG C C E C C
Sbjct: 135 CRGCSQN-GQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPG-----EC 188
Query: 4378 SCRVLVQQRYRHQGPASRGARAGAPCTR---LDGHFRPCLISNCSEDSCTP--PFEFHAC 4432
C + + H G PC L+GH + C + C P+
Sbjct: 189 -CPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQ------CRQRECASLCPYPARPL 241
Query: 4433 GSPCAGLC-------ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECN------ 4479
C +C H S + PC C C G ++ PP C
Sbjct: 242 PGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRCANGSVQCEPLPCPPVPCRHPGKIP 300
Query: 4480 ------CWHTSAAGAGMTLAPGDRLQLG--CKECECRRGELHCTSQGCQGLLPLSEWSEW 4531
C G RLQ C C C+ GE+ C Q C
Sbjct: 301 GQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQEC------------ 348
Query: 4532 SPCGPCLPPSA---LAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRP 4588
P PC P++ L PA EE + P P A +C D G P
Sbjct: 349 -PVTPCALPASGRQLCPACELDGEE--FAEGVQWEPDGRPCTAC------VCQD---GVP 396
Query: 4589 WTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGG 4648
GA LC P Q PGAC SC + QV +G + +A++
Sbjct: 397 KCGAV-LC-PPAPCQHPTQPPGACCPSCDSCTY----HSQVYANG---QNFTDADS---- 443
Query: 4649 GCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCP- 4707
PC C QD T + P +CA R Q G C P RCP
Sbjct: 444 --------------PCHACHCQDGTVTCSLVDCPPTTCA----RPQSGPGQCCP--RCPD 483
Query: 4708 ---PGQLVQDGRCV-----PISSCRC----------GLPSANASWELAPAQAVQLDCQNC 4749
++ DG P CRC P A + L P DC C
Sbjct: 484 CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL-PGTCCPNDCSGC 542
Query: 4750 T-----------------------CVNESLVCPHQEC-------PVLGPWSAWSSCSAPC 4779
C++ ++ C + C PVL P C AP
Sbjct: 543 AFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPA 602
Query: 4780 G----GGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECP---PGQVLSACATSCP 4832
G G RH+ PG + + C PCP P P Q C SC
Sbjct: 603 GCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ--GPCCPSCD 660
Query: 4833 ------------------------CLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVP 4868
CLCW + C + C P CP G C P
Sbjct: 661 GCLYQGKEFASGERFPSPTAACHLCLCW--EGSVSCEPKACAPAL-CP---FPARGDCCP 714
Query: 4869 P-TACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGE 4927
C S L+ +E P C C C GG +C C+ PPG
Sbjct: 715 DCDGCEYLGESY-----LSNQEFPDPREP-------CNLCTCLGGFVTCGRRPCE-PPGC 761
Query: 4928 TWQQVAPGELGLCEQTCLEMNAT----KTQSNCSSARASGCVCQPGHFRSQAGPCVP--- 4980
+ + G Q C T +T + S C CQ G R Q PC P
Sbjct: 762 SHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821
Query: 4981 ----EDHC------ECWHLGRPHLPGSEWQ---EACESCLCLSGRPVCTQ-HCSPLTCAQ 5026
C C GR H G E++ +CE C C +G+ C + C PL C
Sbjct: 822 PHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPC-- 879
Query: 5027 GEEMVLEPGSCCPSCR 5042
+ V E GSCCP CR
Sbjct: 880 -KLQVTERGSCCPRCR 894
Score = 109 bits (272), Expect = 8e-23
Identities = 259/1092 (23%), Positives = 332/1092 (30%), Gaps = 292/1092 (26%)
Query: 2455 PGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVL--------APW 2506
PG P C + C EC S C G+ C C L P
Sbjct: 209 PGDPCRICRCLEGHIQCRQRECASL---CPYPARPLPGTCCPVCDGCFLNGREHRSGEPV 265
Query: 2507 SVWSSCSRSCGLGLTFQRQELLRPP--------LPGGSCP--------RDRFRSQSCFVQ 2550
CS + Q + L PP +PG CP +++SQ F
Sbjct: 266 GSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETF-- 323
Query: 2551 ACPVAGAWAMWEAWGPC-SVSCGGGHQS-RQRSCVDPP---PKNGGAPCPGAS------- 2598
+ G C SC G S ++ C P P +G CP
Sbjct: 324 ---------RLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFA 374
Query: 2599 ------QERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPP--CPPSCLD--------- 2641
+ PC C G + G V CQ PP C PSC
Sbjct: 375 EGVQWEPDGRPCTACVCQDGVP-KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
Query: 2642 -----PKANRSCSG-HCVEGC------RCPPGLLLHDT----RCLPLSECP-CLVGEELK 2684
A+ C HC +G CPP +C P CP C++ EE+
Sbjct: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP--RCPDCILEEEVF 491
Query: 2685 WPGVSFLLGN--CSQCVCEKGELLCQPGGCP-LPCGWSAWSSWAPCDRS-CGSGVR---- 2736
G SF C +C C++G CQP CP PC + P D S C G +
Sbjct: 492 VDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPS 551
Query: 2737 -ARFRSPSNP----PAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAP 2791
A F PS+P G C R C P C C AP
Sbjct: 552 GADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCP----------EPVLLPGECCPQCPAP 601
Query: 2792 GGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQ 2851
G CP PG A +E SPP P L DG +
Sbjct: 602 AG----------CPRPG----AAHARHQEYFSPPGDPCRRCLCL-----------DGSV- 635
Query: 2852 TRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCP----R 2907
SC L C P PC C + L++ E E P P
Sbjct: 636 ----SCQRLPCPPAPCAHPRQ-------GPCCPSC-DGCLYQGKEFASGERFPSPTAACH 683
Query: 2908 LCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA--MARLDSC 2965
LCL + C CP F C P C+ G+ Y S + C
Sbjct: 684 LCLCWEGSVSCEPKACAPALCP---FPARGDCCPDCD-GCEYLGESYLSNQEFPDPREPC 739
Query: 2966 NNCTCVSGKMACTSERC-PVACGWSPWTLWSLCSCSCNVGIRRR---FRAGTAPPAAFGG 3021
N CTC+ G + C C P C P C +C G R +G P
Sbjct: 740 NLCTCLGGFVTCGRRPCEPPGCS-HPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDP 797
Query: 3022 ----AECQGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTC 3077
CQ +M C +PCP PC P ++ R + EF
Sbjct: 798 TCSLCTCQEGSMR---CQKKPCPPALCPHPSPGPCFCPVCHSCLSQGR-EHQDGEEFE-- 851
Query: 3078 GLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCV 3137
GP G C +W C G SC L P C + + C
Sbjct: 852 ------GPA-GSC----EWCRCQAGQVSCVRLQC---------PPLPCKLQVTERGSCCP 891
Query: 3138 PTQDCPCAHEGHLYPPGSTVVRP---CENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQ 3194
+ C AH G +P GS V P C +C C G++ CA Q
Sbjct: 892 RCRGC-LAH-GEEHPEGSRWVPPDSACSSCVCHEGVVT------CAR-----------IQ 932
Query: 3195 CSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAE-------------E 3241
C +SC R H C P CS E E
Sbjct: 933 CISSCAQPRQGPHDCC---------------------PQCSDCEHEGRKYEPGESFQPGA 971
Query: 3242 EPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQ----PPPQGLGDYCEGPRAQ 3297
+PC + C+ P GP S LR R C PP Q L P
Sbjct: 972 DPCEVCICEPQ----PEGPPS---------LRCHRRQCPSLVGCPPSQLL------PPGP 1012
Query: 3298 GEVCQALPCPVTNCT-AIEGAEYSPCGPPCPRSCDDLVH-CVWRCQPGCYCPPGQVLSSN 3355
C ++NC+ + G+E +P P C DL C+ + P CP + +
Sbjct: 1013 QHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPP 1072
Query: 3356 GAIC--VQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP------- 3406
G+ C + SC+ G+ G R D C C+C+ G + C C
Sbjct: 1073 GSCCPVCRAPTQSCVH--QGREVASGERWT-VDTCTSCSCMAGTVRCQSQRCSPLSCGPD 1129
Query: 3407 -----VPGGWCP 3413
PG CP
Sbjct: 1130 KAPALSPGSCCP 1141
Score = 105 bits (262), Expect = 1e-21
Identities = 234/927 (25%), Positives = 284/927 (30%), Gaps = 242/927 (26%)
Query: 1254 DECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCF 1313
D C GH +++SQE LQ G V +C +C EQ C V C
Sbjct: 308 DGCEYQGH--QYQSQETFRLQERGLCVRCSC-QAGEVSCEEQE------CPVTPCA---- 354
Query: 1314 CPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKD---CGNCTCQEGQWHCGG---DGG 1367
L G L PA CE F G + D C C CQ+G CG
Sbjct: 355 -----LPASGRQLCPA---CELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPA 406
Query: 1368 HCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGH 1427
C+ P G A C C H + N + D + C A C +G +TCS
Sbjct: 407 PCQH--PTQPPG-ACCPSCDSCTYHSQVYANGQNFTDA--DSPCHACHCQDGTVTCSLVD 461
Query: 1428 CLPLALL---------CDRQDDC---------GDGTDEPSYPCPQGLLACADGRCLP--- 1466
C P C R DC G+ P PC + C P
Sbjct: 462 CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPC 521
Query: 1467 ---------PALLCDG-----------HPDCLDAADEESCLGQVTCVPGEVSCVDGTCLG 1506
P C +P D C+ G V C+ C+
Sbjct: 522 PRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVP 581
Query: 1507 AIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPS----------PGS-------L 1549
CP+ PG C P P P PG + PG L
Sbjct: 582 L--------PCPEPVLL-PGEC-CPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCL 631
Query: 1550 DTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCD----QEEDCADGSDERGCGGPCAP 1605
D + S P PC G C P CD Q ++ A G ER A
Sbjct: 632 DGSVSCQRLPCPPAPCA----HPRQGPCCPS---CDGCLYQGKEFASG--ERFPSPTAAC 682
Query: 1606 HHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACGGLPALGGP--NRTGLPCPEYTCPN 1663
H C G P+ + P D PD C G LG + P P C
Sbjct: 683 HLCLCWEGSVSCEPKACAPALCPFPARGDCCPD-CDGCEYLGESYLSNQEFPDPREPCNL 741
Query: 1664 GTCIGFQLVCDGQPDCGRPGQVGP-------SPEEQGCGAWGPWSPWG-----PCSRTCG 1711
TC+G + C +P C PG P P QGC G + G P TC
Sbjct: 742 CTCLGGFVTCGRRP-CEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCS 800
Query: 1712 PWG-QGRSRRCSPLGLLVLQNCPG---PEHQSQACFTAACPV---------DGEWSTWSP 1758
Q S RC + CP P CF C DGE P
Sbjct: 801 LCTCQEGSMRCQK------KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE-EFEGP 853
Query: 1759 WSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMF 1818
C E CR Q C Q C LP L T + CP+ C GE
Sbjct: 854 AGSC-EWCR-CQAGQVSCVRLQ-----CPPLPCKLQVTERGSCCPR--CRGCLAHGE--- 901
Query: 1819 QPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCV----WPRQ-----CP 1869
+ G PPD C S C C EG V + C+ PRQ CP
Sbjct: 902 ----------EHPEGSRWVPPDSACSS--CVCHEGVVTCARIQCISSCAQPRQGPHDCCP 949
Query: 1870 ----CLVDGARYWPGQRIK--AD-CQLCICQ---DGRPR-RCRLN--------------- 1903
C +G +Y PG+ + AD C++CIC+ +G P RC
Sbjct: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
Query: 1904 -------PDCAVDCGWSSWSPWAKCLGP------CGSQSIQW----------SFRSSNNP 1940
P CA S L P C Q + W S S
Sbjct: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
Query: 1941 RPSGRGRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSP 2000
P G C + R P + C HQG+ GERW C C C+ S
Sbjct: 1070 TPPG---SCCPVCRA-------PTQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQ 1119
Query: 2001 YCPLGSCPQGWVLVEGTGESCCHCALP 2027
C SC G SCC LP
Sbjct: 1120 RCSPLSCGPDKAPALSPG-SCCPRCLP 1145
Score = 93.6 bits (231), Expect = 5e-18
Identities = 199/874 (22%), Positives = 271/874 (31%), Gaps = 223/874 (25%)
Query: 1328 PASCPCEWGRN-SFPPGSVLQKD-CGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQE 1385
PAS C WG ++P G+ + D C C CQ+G HCG + +P C C +
Sbjct: 91 PASPQC-WGLGRAWPEGARWEPDACTACVCQDGAAHCGP-----QAHLPHCRG----CSQ 140
Query: 1386 NGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGT 1445
NG + G+ + C C G + C C L +C +
Sbjct: 141 NGQTYGN----------GETFSPDACTTCRCLTGAVQCQGPSCSEL--------NCLESC 182
Query: 1446 DEPSYPCPQGLLACADGRCL-----------PPALLC---DGHPDCLDAADEESCLGQVT 1491
P CP + C +G P +C +GH C C
Sbjct: 183 TPPGECCP---ICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPAR 239
Query: 1492 CVPGEVSCV-DGTCLGAIQLCDGVWDCPDGADEGPGHC----------PLPSLPTPPAST 1540
+PG V DG L + G P G+ + HC PLP P P
Sbjct: 240 PLPGTCCPVCDGCFLNGREHRSGE---PVGSGDPCSHCRCANGSVQCEPLPCPPVP--CR 294
Query: 1541 LPGPSPGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGS------ 1594
PG PG P C E++ G + +R + C S
Sbjct: 295 HPGKIPGQC------------CPVCDGCEYQ-GHQYQSQETFRLQERGLCVRCSCQAGEV 341
Query: 1595 --DERGCG-GPCAPHHAPCARGPHC-VSPEQLCDGVRQCPDGSDEGPDAC-GGLPALGGP 1649
+E+ C PCA + P C + E+ +GV+ PDG C G+P G
Sbjct: 342 SCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAV 401
Query: 1650 NRTGLPCPEYTCPNGTCIGFQLVCDGQPDCGRPGQVGPSPE-----EQGCGAWGPWSPWG 1704
PC T P G C C C QV + + + C A
Sbjct: 402 LCPPAPCQHPTQPPGAC------CPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTV 455
Query: 1705 PCS------RTCGPWGQGRSRRCSPLGLLVL------------------QNCPGPEHQSQ 1740
CS TC G + C +L Q C E +
Sbjct: 456 TCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAH 515
Query: 1741 ACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHS------PQNGGRTCAALPGGLH 1794
C CP + P + C C G ++ S P + R C L G +
Sbjct: 516 -CQPRPCP-RAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQ 573
Query: 1795 STRQ---TKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCP 1851
+ PCP+ C + P P + PP PC C C
Sbjct: 574 CLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRR--CLCL 631
Query: 1852 EGQVLGSE-----GWCVWPRQ---CP----CLVDGARYWPGQRI---KADCQLCICQDG- 1895
+G V C PRQ CP CL G + G+R A C LC+C +G
Sbjct: 632 DGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS 691
Query: 1896 ---RPRRCR-------LNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGR 1945
P+ C DC DC G + + S+ SN P R
Sbjct: 692 VSCEPKACAPALCPFPARGDCCPDCD--------------GCEYLGESY-LSNQEFPDPR 736
Query: 1946 GRQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGPCRVCQCLHNL--TAHCSPYCP 2003
EPC C G G R PC C H L + HC P C
Sbjct: 737 ----------------EPCNLCTCLGGFVTCGRR----PCEPPGCSHPLIPSGHCCPTCQ 776
Query: 2004 LGSC-------PQGWVLVEGTGESCCHCAL-PGENQTVQPMATPAAAPAPSPQIRFPLAT 2055
C G L + +C C G + + PA P PSP
Sbjct: 777 --GCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP-------- 826
Query: 2056 YILPPSGDPCYSPLGLAGLAEGSLHASSQQLEHP 2089
PC+ P+ + L++G H ++ E P
Sbjct: 827 -------GPCFCPVCHSCLSQGREHQDGEEFEGP 853
Score = 91.3 bits (225), Expect = 2e-17
Identities = 244/1050 (23%), Positives = 322/1050 (30%), Gaps = 237/1050 (22%)
Query: 1152 DASNDLRSRQGVLEPTA--ELAAHSWRLSPLCPEPGDL-PHPCTMNTHRAGWARARCGAL 1208
+ + DL++R LE + W L PE P CT + G A CG
Sbjct: 72 EQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDG--AAHCG-- 127
Query: 1209 LQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQ 1268
P L H Q + + D+ C CL A+ C+
Sbjct: 128 --PQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSE---------- 175
Query: 1269 ELCSLQCEGGQVYEACGPT---CPPTC-----HEQHPE----PGWHCQVVACVEG----- 1311
L C E+C P CP C H +H + PG C++ C+EG
Sbjct: 176 ----LNC-----LESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
Query: 1312 -----CFCPEGTLLHGGACLEPASCPCEWG--------RNSFPPGSVLQKDCGNCTCQEG 1358
CP G C CP G R+ P GS C +C C G
Sbjct: 227 QRECASLCPYPARPLPGTC-----CPVCDGCFLNGREHRSGEPVGS--GDPCSHCRCANG 279
Query: 1359 QWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSD-----EEG-CA 1412
C + C VP G+ G C P C+ Q + E G C
Sbjct: 280 SVQC--EPLPCPP-VPCRHPGKI----PGQCCPVCDGCEYQGHQYQSQETFRLQERGLCV 332
Query: 1413 APGCGEGQMTCSSGHC--LPLALLCDRQDDCG-----------------DGTDEPSYPCP 1453
C G+++C C P AL + C DG + C
Sbjct: 333 RCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQ 392
Query: 1454 QGLLACADGRCLPPALLCDGHPD-----CLDAADEESCLGQVTCVPGEVSCVDGTCLGAI 1508
G+ C G L P C HP C + D + QV + D C A
Sbjct: 393 DGVPKC--GAVLCPPAPCQ-HPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPC-HAC 448
Query: 1509 QLCDG-----VWDCPDGA----DEGPGHCPLPSLPTPPASTLPGPSPGSLDTASSPLASA 1559
DG + DCP GPG C P P L + + +
Sbjct: 449 HCQDGTVTCSLVDCPPTTCARPQSGPGQC----CPRCPDCILEE------EVFVDGESFS 498
Query: 1560 SPAPPCGPFEFRCGSGECTPR------------GWRCDQE-EDCADGSDERGCGGPCAPH 1606
P PC + G C PR G C + CA G E G PH
Sbjct: 499 HPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADF-PH 557
Query: 1607 HAPCARGPHCVSPEQLCDGVR----QCPDGSDEGPDACGGLPALGGPNRTGLPCP---EY 1659
+ R C+S C R CP+ + C PA G R G EY
Sbjct: 558 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEY 617
Query: 1660 TCPNGTCIGFQLVCDGQPDCGR-PGQVGPSPEEQGCGAWGPWSPWGPCSRTC-GPWGQGR 1717
P G L DG C R P P + GPC +C G QG+
Sbjct: 618 FSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQ----------GPCCPSCDGCLYQGK 667
Query: 1718 S-----RRCSPLGLLVLQNC--PGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTM 1770
R SP L C + +AC A CP C +
Sbjct: 668 EFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYL 727
Query: 1771 TRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPN--------------------A 1810
+ Q + P+ C L G + R +PC GC +
Sbjct: 728 SNQ-EFPDPREPCNLCTCLGGFVTCGR--RPCEPPGCSHPLIPSGHCCPTCQGCRYHGVT 784
Query: 1811 TCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPC 1870
T SGE + P P C G + C PC P CP S G C P C
Sbjct: 785 TASGETLPDPLDPTCSLCTCQEGSMRCQKK-PC--PPALCPHP----SPGPCFCPVCHSC 837
Query: 1871 LVDGARYWPGQRIKA---DCQLCICQDGR---------PRRCRLNPDCAVDCGWSSWSPW 1918
L G + G+ + C+ C CQ G+ P C+L C
Sbjct: 838 LSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSC-------C 890
Query: 1919 AKCLG--------PCGSQSIQWSFRSSNNPRPSG----RGRQCRGIHRKARRCQTE---P 1963
+C G P GS+ + S+ G QC + R+ +
Sbjct: 891 PRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQ 950
Query: 1964 CEGCEHQGQVHRVGERWHGG--PCRVCQCLH------NLTAHCSPYCPLGSCPQGWVLVE 2015
C CEH+G+ + GE + G PC VC C +L H L CP +L
Sbjct: 951 CSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPP 1010
Query: 2016 GTGESCCHCALPGENQTVQPMATPAAAPAP 2045
G C CA N + + + A P P
Sbjct: 1011 GPQHCCPTCAEALSNCSEGLLGSELAPPDP 1040
Score = 82.4 bits (202), Expect = 1e-14
Identities = 130/527 (24%), Positives = 171/527 (32%), Gaps = 151/527 (28%)
Query: 4685 SCADLWDRVQCLQGPCRPGCRC-----PPGQLVQDGRCVPISSCRCGLPSANASWELAPA 4739
+C L VQC QGP C PPG+ C PI G + WE
Sbjct: 158 TCRCLTGAVQC-QGPSCSELNCLESCTPPGE------CCPICCTEGG-----SHWEHGQE 205
Query: 4740 QAVQLD-CQNCTCVNESLVCPHQECPVLGPWSAW---SSCSAPCGGGTME--RHRTCEGG 4793
D C+ C C+ + C +EC L P+ A +C C G + HR+ E
Sbjct: 206 WTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPV 265
Query: 4794 PGVAPCQ-AQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPG 4852
PC + +C PCP P C H PG I PG
Sbjct: 266 GSGDPCSHCRCANGSVQCEPLPCPPVP---------------CRH--PGKI-------PG 301
Query: 4853 CGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGG 4912
CP C C H T L+E+ C RC C G
Sbjct: 302 QCCP--------VC---DGCEYQGHQYQSQETFRLQERGL-----------CVRCSCQAG 339
Query: 4913 AFSCSLVDCQVPP---GETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPG 4969
SC +C V P + +Q+ P CE E A Q + CVCQ G
Sbjct: 340 EVSCEEQECPVTPCALPASGRQLCPA----CELDGEEF-AEGVQWEPDGRPCTACVCQDG 394
Query: 4970 ---------------HFRSQAGPCVPEDHCE-CWHLGRPHLPGSEWQEA---CESCLCLS 5010
H G C P C+ C + + + G + +A C +C C
Sbjct: 395 VPKCGAVLCPPAPCQHPTQPPGACCPS--CDSCTYHSQVYANGQNFTDADSPCHACHCQD 452
Query: 5011 GRPVCT-QHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCY- 5068
G C+ C P TCA+ + PG CCP C P C L E+ F G +
Sbjct: 453 GTVTCSLVDCPPTTCARPQS---GPGQCCPRC---------PDCILEEEV--FVDGESFS 498
Query: 5069 --LDQVEVSYC-SGYCPSSTHVMPEEPYLQ--------SQCDCCSYR----------LDP 5107
D + C G+ P P + C C++ P
Sbjct: 499 HPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADFPHP 558
Query: 5108 ESPVRILNLRCLGGHT-------------EPVVLPVIHSCQCSSCQG 5141
P R+ RCL G+ EPV+LP QC + G
Sbjct: 559 SDPCRL--CRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAG 603
Score = 69.7 bits (169), Expect = 7e-11
Identities = 157/638 (24%), Positives = 197/638 (30%), Gaps = 154/638 (24%)
Query: 1517 CPDGADEGPGHC-PLPSLPTPPASTLPGPSPGSLDTASSPLASAS---------PAPPCG 1566
C DGA HC P LP + G + G+ +T S + P C
Sbjct: 119 CQDGA----AHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCS 174
Query: 1567 PFEFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHAPCARGPHCVSPEQLC--- 1623
E C CTP G C C +G G PC R C+ C
Sbjct: 175 --ELNCLES-CTPPGECCPI--CCTEGGSHWEHGQEWTTPGDPC-RICRCLEGHIQCRQR 228
Query: 1624 DGVRQCPDGSDEGPDAC----------GGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVC 1673
+ CP + P C G G P +G PC C NG+ L C
Sbjct: 229 ECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
Query: 1674 DGQPDCGRPGQVGPS--PEEQGCGAWGPWSPWGPCSRTCGPWGQGRSRRCSPLGLLVL-- 1729
P C PG++ P GC G T +G RCS V
Sbjct: 289 PPVP-CRHPGKIPGQCCPVCDGCEYQGHQY---QSQETFRLQERGLCVRCSCQAGEVSCE 344
Query: 1730 -QNCPG-----PEHQSQACFTAACPVDG-EWSTWSPWSVCSEPCRGTMTRQRQCHSPQNG 1782
Q CP P Q C AC +DG E++ W PC + Q P+ G
Sbjct: 345 EQECPVTPCALPASGRQLC--PACELDGEEFAEGVQWEPDGRPCTACVC---QDGVPKCG 399
Query: 1783 GRTCAALPGGLHSTRQTKPCPQ-DGC---PNATCSGELMFQPCAPCPLTCDDISGQVT-- 1836
C P + CP D C +G+ +PC C G VT
Sbjct: 400 AVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCH-ACHCQDGTVTCS 458
Query: 1837 ---CPPDW---PCGSPGCWCPEGQVLGSEGWCVWPRQCP-CLVDGARYWPGQRI---KAD 1886
CPP P PG CP +CP C+++ + G+ +
Sbjct: 459 LVDCPPTTCARPQSGPGQCCP---------------RCPDCILEEEVFVDGESFSHPRDP 503
Query: 1887 CQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRG 1946
CQ C CQ+G A C PRP R
Sbjct: 504 CQECRCQEGH----------------------AHC-----------------QPRPCPRA 524
Query: 1947 RQCRGIHRKARRCQTEPCEGCEHQGQVHRVGERW--HGGPCRVCQCLHNLTAHCSPYCPL 2004
C H C C GC G+ + G + PCR+C+CL + C
Sbjct: 525 -PC--AHPLPGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVP 581
Query: 2005 GSCPQGWVLVEGTGESCCHCALPGENQTVQPMATPAAAPAPSPQIRFPLATYILPPSGDP 2064
CP+ +L GE C C PA A P P P GDP
Sbjct: 582 LPCPEPVLL---PGECCPQC--------------PAPAGCPRPGAAHARHQEYFSPPGDP 624
Query: 2065 CYSPLGLAGLAEGSLHASSQQLEHPTQAALLGAPTQGP 2102
C L L G S Q+L P A P QGP
Sbjct: 625 CRRCLCLDG------SVSCQRL--PCPPAPCAHPRQGP 654
Score = 68.9 bits (167), Expect = 1e-10
Identities = 220/972 (22%), Positives = 298/972 (30%), Gaps = 242/972 (24%)
Query: 791 DPGSDCLCPVLSAYARRCAQEGASP-PWRNQTLCPVMCPGGQEYRECAPAC------GQH 843
DP S C C S +C P P R+ P PG +C P C G
Sbjct: 269 DPCSHCRCANGSV---QCEPLPCPPVPCRH----PGKIPG-----QCCPVCDGCEYQGHQ 316
Query: 844 CGKPED--CGELGSCVAGCNCPLGLLWDPEGQC------VPPS---LCP-CQLGARRYAP 891
E E G CV C+C G + E +C +P S LCP C+L +A
Sbjct: 317 YQSQETFRLQERGLCVR-CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAE 375
Query: 892 G---SATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCP 948
G + C C+CQ+ G+ C A CP A C PGAC +CDS + +
Sbjct: 376 GVQWEPDGRPCTACVCQD-GVPKCGAVLCPP-APCQHP-TQPPGACCPSCDSCTYHSQVY 432
Query: 949 AGSTD---------GCVCPPGTVLLDERCVPPDLCPCRHSGQWY----LPNATIQED--- 992
A + C C GTV PP C SG P+ ++E+
Sbjct: 433 ANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFV 492
Query: 993 -----------CNVCVCRGRQWHCTGQRRSGRCQASGAPHYV-------TFDGLAF---T 1031
C C C+ HC + C + H + G AF
Sbjct: 493 DGESFSHPRDPCQECRCQEGHAHC----QPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKE 548
Query: 1032 YPGACEYLLVREASGLFTVSAQNLPCGAS---GLTCTKALAVRLEGTVVHMLRGRAVTVN 1088
YP ++ + L + N+ C A L C + + + E
Sbjct: 549 YPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPG 608
Query: 1089 GVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGT---RVLVQLSPQFRGRVAGL 1145
+ ++ PG RR L DG R+ +P R
Sbjct: 609 AAHARHQEYFSPPGDPCRRC-------------LCLDGSVSCQRLPCPPAPCAHPRQGPC 655
Query: 1146 CGDFDGDASNDLRSRQGVLEPTAELAAH---SWRLSPLCPEPGDLPHPCTMNTHRAGWAR 1202
C DG G P+ A H W S C P C AR
Sbjct: 656 CPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFP------AR 709
Query: 1203 ARC-----GALLQPLFTLCHAEVP-PQQHYEWCL----YDACG---CDSGGDCECLCSAI 1249
C G L + E P P++ C + CG C+ G CS
Sbjct: 710 GDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPG-----CSHP 764
Query: 1250 ATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCP-PTCHE-------------- 1294
+ C R+ S G + + PTC TC E
Sbjct: 765 LIPSGHCCPTCQGCRYHGVTTAS----GETLPDPLDPTCSLCTCQEGSMRCQKKPCPPAL 820
Query: 1295 -QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNC 1353
HP PG CFCP + H +CL + P GS C C
Sbjct: 821 CPHPSPG----------PCFCP---VCH--SCLSQGREHQDGEEFEGPAGS-----CEWC 860
Query: 1354 TCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGS----DEE 1409
CQ GQ C E + C C+ HG ++ +GS +
Sbjct: 861 RCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHG------EEHPEGSRWVPPDS 914
Query: 1410 GCAAPGCGEGQMTCSSGHCLPLAL--------LCDRQDDC---------GDGTDEPSYPC 1452
C++ C EG +TC+ C+ C + DC G+ + PC
Sbjct: 915 ACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPC 974
Query: 1453 --------PQG-------------LLACADGRCLPPA--LLCDGHPDCLDAAD--EESCL 1487
P+G L+ C + LPP C P C +A E L
Sbjct: 975 EVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCC---PTCAEALSNCSEGLL 1031
Query: 1488 GQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLP---GP 1544
G P C C LC CP+ + CPL TPP S P P
Sbjct: 1032 GSELAPPD--PCYTCQCQDLTWLCIH-QACPELS------CPLSERHTPPGSCCPVCRAP 1082
Query: 1545 SPGSL----DTASSPLASASPAPPCGPF--EFRCGSGECTPRGWRCDQEEDCADGSDERG 1598
+ + + AS + C RC S C+P D+ + GS
Sbjct: 1083 TQSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGS---- 1138
Query: 1599 CGGPCAPHHAPC 1610
C C P A C
Sbjct: 1139 CCPRCLPRPASC 1150
Score = 56.2 bits (134), Expect = 8e-07
Identities = 58/216 (26%), Positives = 79/216 (36%), Gaps = 52/216 (24%)
Query: 3175 SSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLC 3234
+SW +EG W P CSA C + AR + V L ++P C
Sbjct: 1309 NSWQVSEG--LW----PGRPCSAGREVDPCRAAGYRARREANARCGV----LKSSPFSRC 1358
Query: 3235 SG---PEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC 3291
PE C+ C +CG G + CD + +C
Sbjct: 1359 HAVVPPEPFFAACVYDLC-----------------ACGPGSSADACLCDAL--EAYASHC 1399
Query: 3292 EG----PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSC--------DDLVHCVWR 3339
P +G + CP+ G + CGPPCPR+C + HCV
Sbjct: 1400 RQAGVTPTWRGPTLCVVGCPLER-----GFVFDECGPPCPRTCFNQHIPLGELAAHCVRP 1454
Query: 3340 CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQR 3375
C PGC CP G L + A C+ P C + LLTG +
Sbjct: 1455 CVPGCQCPAG--LVEHEAHCIPPEACPQV-LLTGDQ 1487
Score = 52.4 bits (124), Expect = 1e-05
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 9/70 (12%)
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGI-----ECTGFCAPGCTCPPGLFLHN 2936
C CP F ++C G PCPR C Q + C C PGC CP GL H
Sbjct: 1414 CVVGCPLERGF-VFDEC---GPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHE 1469
Query: 2937 ASCLPRSQCP 2946
A C+P CP
Sbjct: 1470 AHCIPPEACP 1479
Score = 49.7 bits (117), Expect = 8e-05
Identities = 51/173 (29%), Positives = 63/173 (36%), Gaps = 41/173 (23%)
Query: 2533 PGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGG- 2591
PG C R V C AG A EA C V SR + V P P
Sbjct: 1319 PGRPCSAGRE------VDPCRAAGYRARREANARCGVLKSSPF-SRCHAVVPPEPFFAAC 1371
Query: 2592 -----APCPGASQERAPC-------------GLQPCSGG-----TDCELGRVYVSADLCQ 2628
A PG+S + C G+ P G C L R +V D C
Sbjct: 1372 VYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVF-DECG 1430
Query: 2629 KGLVPPCPPSCLDP-----KANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECP 2676
PPCP +C + + C CV GC+CP GL+ H+ C+P CP
Sbjct: 1431 ----PPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEACP 1479
Score = 46.6 bits (109), Expect = 6e-04
Identities = 85/352 (24%), Positives = 110/352 (31%), Gaps = 59/352 (16%)
Query: 1764 EPCRGTMTRQRQ-----CH--SPQNGGRTCAALPGGLHSTRQTKPCP-QDGCPNATCSGE 1815
E + TR RQ CH SPQ G A G C QDG A C +
Sbjct: 72 EQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGA--AHCGPQ 129
Query: 1816 LMFQPCAPCPLTCDDISGQVTCPPDWPC-------GSPGCWCPEGQVLGSEGWCVWPRQC 1868
C C T PD C G+ C P L C P +C
Sbjct: 130 AHLPHCRGCSQNGQTYGNGETFSPD-ACTTCRCLTGAVQCQGPSCSELNCLESCTPPGEC 188
Query: 1869 P--CLVDGARYWP-GQRIKAD---CQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCL 1922
C +G +W GQ C++C C +G + CR +CA C + + C
Sbjct: 189 CPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQ-CRQR-ECASLCPYPARPLPGTCC 246
Query: 1923 GPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEP------------------- 1963
C + R + P G G C Q EP
Sbjct: 247 PVCDGCFLNG--REHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCC 304
Query: 1964 --CEGCEHQGQVHRVGERW---HGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTG 2018
C+GCE+QG ++ E + G C C C + CP+ C L
Sbjct: 305 PVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPC----ALPASGR 360
Query: 2019 ESCCHCALPGENQTVQPMATPAAAPAPS--PQIRFPLATYILPPSGDPCYSP 2068
+ C C L GE P P + Q P +L P PC P
Sbjct: 361 QLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPA-PCQHP 411
Score = 40.0 bits (92), Expect = 0.060
Identities = 44/169 (26%), Positives = 60/169 (35%), Gaps = 36/169 (21%)
Query: 423 CAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCE------RLCPGGQLYS 476
C + G +G++ A F S AC H+ + W CE LCP
Sbjct: 655 CCPSCDGCLYQGKEFASGERFPSPTAAC---HLCLCWEGSVSCEPKACAPALCPF-PARG 710
Query: 477 DCVSLCPPSCEAVGQG-----EEESCREECVSGCECPRGLFWNGTL----------CVPA 521
DC C CE +G+ E RE C + C C G G +P+
Sbjct: 711 DCCPDCD-GCEYLGESYLSNQEFPDPREPC-NLCTCLGGFVTCGRRPCEPPGCSHPLIPS 768
Query: 522 AHC--PCYYCRQRYVPG-------DTVRQLCNPCVCRDGRWHCAQALCP 561
HC C CR V D + C+ C C++G C + CP
Sbjct: 769 GHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCP 817
Score = 39.3 bits (90), Expect = 0.10
Identities = 57/203 (28%), Positives = 71/203 (34%), Gaps = 45/203 (22%)
Query: 450 CARRHIHIRWRKPGFCERLCP--GGQLYSDCVSLCPPSCEAVGQ----GEEESCREECVS 503
C HI R R+ C LCP L C +C C G+ GE + C S
Sbjct: 218 CLEGHIQCRQRE---CASLCPYPARPLPGTCCPVCD-GCFLNGREHRSGEPVGSGDPC-S 272
Query: 504 GCECPRGLFWNGTL-C--VPAAH--------CP----CYYCRQRYVPGDTVRQ----LCN 544
C C G L C VP H CP C Y +Y +T R LC
Sbjct: 273 HCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCV 332
Query: 545 PCVCRDGRWHCAQALCP-AECAVGGDGHYL----TFDGRSYS---FW--GGQGCRYSLVQ 594
C C+ G C + CP CA+ G L DG ++ W G+ C + Q
Sbjct: 333 RCSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQ 392
Query: 595 DYVKGQLLILLEHGACDAGSCLH 617
D V +L C C H
Sbjct: 393 DGVPKCGAVL-----CPPAPCQH 410
Score = 37.4 bits (85), Expect = 0.39
Identities = 34/105 (32%), Positives = 43/105 (40%), Gaps = 23/105 (21%)
Query: 463 GFCERL-CPGGQLYSDCVSL-CPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVP 520
G CE C GQ+ CV L CPP + E SC C GC
Sbjct: 855 GSCEWCRCQAGQV--SCVRLQCPPLPCKLQVTERGSCCPRC-RGC--------------- 896
Query: 521 AAHCPCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECA 565
AH + R+VP D+ C+ CVC +G CA+ C + CA
Sbjct: 897 LAHGEEHPEGSRWVPPDSA---CSSCVCHEGVVTCARIQCISSCA 938
Score = 36.2 bits (82), Expect = 0.87
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 1806 GCPNATCSGELMFQPCAP-CPLTCDDIS---GQVTCPPDWPCGSPGCWCPEGQVLGSEGW 1861
GCP +F C P CP TC + G++ PC PGC CP G ++ E
Sbjct: 1417 GCP---LERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPC-VPGCQCPAG-LVEHEAH 1471
Query: 1862 CVWPRQCP 1869
C+ P CP
Sbjct: 1472 CIPPEACP 1479
Score = 35.0 bits (79), Expect = 1.9
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 8/62 (12%)
Query: 3090 CPRDKQWL--DCAQG-PASCAELSAPRGTN-----QTCHPGCHCPSGMLLLNNVCVPTQD 3141
CP ++ ++ +C P +C P G + C PGC CP+G++ C+P +
Sbjct: 1418 CPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
Query: 3142 CP 3143
CP
Sbjct: 1478 CP 1479
Score = 33.1 bits (74), Expect = 7.3
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 23/103 (22%)
Query: 481 LCPPSCEAVGQGEEESCREEC----VSGCECPRGLFWNGT-LCVPA----------AHCP 525
LCP +CE G+ E + E + C C G+ G LC PA A CP
Sbjct: 362 LCP-ACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP 420
Query: 526 ----CYYCRQRYVPGDTVRQL---CNPCVCRDGRWHCAQALCP 561
C Y Q Y G C+ C C+DG C+ CP
Sbjct: 421 SCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCP 463
Score = 33.1 bits (74), Expect = 7.3
Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 21/119 (17%)
Query: 462 PGFCERLCPGGQLYSDCVSLCPPS-----CEAVGQGEEESCREECVSGCECPRGLFWNGT 516
P C GG+ Y PS C + G + CV CP + G
Sbjct: 536 PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS-GNVQCLARRCVP-LPCPEPVLLPGE 593
Query: 517 LC--VPA-AHCP----CYYCRQRYV--PGDTVRQLCNPCVCRDGRWHCAQALC-PAECA 565
C PA A CP + Q Y PGD C C+C DG C + C PA CA
Sbjct: 594 CCPQCPAPAGCPRPGAAHARHQEYFSPPGDP----CRRCLCLDGSVSCQRLPCPPAPCA 648
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 210 bits (535), Expect = 3e-53
Identities = 211/794 (26%), Positives = 310/794 (39%), Gaps = 85/794 (10%)
Query: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVTMG 251
++TC + HY TFDG +HF G C YLLA T ++ + + V+
Sbjct: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
Query: 252 PE--------EVLIQAGN---VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVR 300
E ++LI G+ V V + + L + + G + G++V
Sbjct: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
Query: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
D SISV T GLCG YN P DDF+ P G AM G SWR+ ++
Sbjct: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
Query: 361 CLDAVEVAQGC-DPLGLIDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
C GC D DA E + D C L +GP +C V P + +
Sbjct: 499 C------DSGCVDNCTQCDAATEALYF---GSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
Query: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERL--CPGGQL 474
C++ C+ G+ +C +Y C I I WR C CP
Sbjct: 550 CVYDLCSVRDNGT-------LLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSH 602
Query: 475 YSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYV 534
YS C S CP +C + +C C GCEC +G + + CVP C C + Y
Sbjct: 603 YSVCTSSCPDTCSDL--TASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYT 660
Query: 535 PGDTVRQLCN---PCVCRD-GRWHCAQALCPA--ECAVGGDGH----------------- 571
G+ N C+C + G +C C + CAV DG+
Sbjct: 661 MGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAV-EDGYQGCFPKRETVCLLSQNQ 719
Query: 572 -YLTFDGRSYSFWGGQGCRYSLVQDYVK--GQLLILLEHGACDAG-SCLHAISVSLEDTH 627
TFDG SY+F Y+L++ + L I + DAG + L + + + D
Sbjct: 720 VLHTFDGASYAF--PSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQE 777
Query: 628 IQLRDSGA--VLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYIT 684
+++ GA V +NGQ+V LP+ G L + R ++ + G + + YI
Sbjct: 778 VKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNS-TTVESKGVVTVQYSDIGLLYIR 836
Query: 685 LDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSP 744
L + + GLCG + N D+F P G ++A F + + C E LL
Sbjct: 837 LSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESW-TTFEEICNGECGDLLKA 895
Query: 745 CTTHSQRHAF--AEAACAILH---SSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCP 799
C S+ F + + C I++ +S F ECH +V+ +Y CL +C LC
Sbjct: 896 CNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCD 955
Query: 800 VLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGEL--GSC 856
++ YA C PWR CP+ CP + EC C + C + G + SC
Sbjct: 956 SVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC-ETLTLGPICVDSC 1013
Query: 857 VAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECN-RCICQERGLWN---C 912
GC C G QCV S C C + A + + + C G N C
Sbjct: 1014 SEGCQCDEGYAL-LGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072
Query: 913 TARHCPSQAFCPRE 926
C +C E
Sbjct: 1073 ETIPCKDDEYCMEE 1086
Score = 194 bits (493), Expect = 2e-48
Identities = 195/788 (24%), Positives = 296/788 (37%), Gaps = 109/788 (13%)
Query: 205 TFDGRHYHFLGRCTY-LLAGAADSTWAVHLTPGDRCPQPGHCQ----RVTMGPEEVLIQ- 258
TFDG Y F +Y LL + + + + P G R+ + +EV I
Sbjct: 723 TFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGG 782
Query: 259 --AGNVSVKGQLV------PEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISIS 310
A V + GQ V P G+ + + V S G+ V V+ G + I
Sbjct: 783 IGASEVKLNGQEVELPFFHPSGKLEIYRNKN-----STTVESKGV-VTVQYSDIGLLYIR 836
Query: 311 VDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSW----RLPGSESGCLDAVE 366
+ + T GLCG YN D+F P G A F SW + E G +
Sbjct: 837 LSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECG-----D 891
Query: 367 VAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGA 426
+ + C+ D+++ + + + F +CH V+ Y+ CLF C
Sbjct: 892 LLKACNN----DSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSG 947
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPS 485
G + +C + A Y AC + + WR FC CP + +C++ C +
Sbjct: 948 -------GNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTET 999
Query: 486 CEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQR------------- 532
CE + G C + C GC+C G G+ CV + C C + +
Sbjct: 1000 CETLTLGP--ICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDC 1057
Query: 533 ----YVPGDTVRQLCNPCVCRD--------GRWHCAQALCPAECAVGGDGHYLTFDGRSY 580
Y G R C C+D G ++C QA A C V G GHYLTFDG +
Sbjct: 1058 QIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYC-QARTDASCIVSGYGHYLTFDGFPF 1116
Query: 581 SFWGG-------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDS 633
F G R S + K + E + + V++ I + +
Sbjct: 1117 DFQTSCPLILCTTGSRPS-SDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRA 1175
Query: 634 --GAVLVNGQDVGLPW-IGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHA 690
VLVN + + LP +G +++ ++ G +V++ ++ IT+
Sbjct: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLS-ITVPRSMQ 1234
Query: 691 HQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKF-------QVAGKGRCPSEDSALLS 743
+ GLCG + N DD P G + +S+ F + QV RCPS
Sbjct: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPS------- 1287
Query: 744 PCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVL 801
+ + + C+++ ++ F +CH V+ FY CL C C L
Sbjct: 1288 --CAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWL 1345
Query: 802 SAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---PEDCGELGSCV 857
YA C +G + WRN T C V CP Y C C C DC CV
Sbjct: 1346 QNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CV 1403
Query: 858 AGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM-KEC-NRCICQERGLWNCTAR 915
GC+C G + + + C+ P C C + Y P +C RC C R + C R
Sbjct: 1404 EGCHCDAGYVLNGK-SCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPR 1462
Query: 916 HCPSQAFC 923
C S C
Sbjct: 1463 QCKSDEEC 1470
Score = 176 bits (445), Expect = 7e-43
Identities = 187/744 (25%), Positives = 276/744 (37%), Gaps = 107/744 (14%)
Query: 182 GQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA--GAADST-----WAVHLT 234
G L+ R A+C HY TFDG + F C +L G+ S+ + V
Sbjct: 1087 GGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAK 1146
Query: 235 PGDRCPQPGHCQR---VTMGPEEVLIQAG---NVSVKGQLVPEGQSWLLHGLSLQWLGDW 288
DR P + VT+ ++I V V + + +++ G
Sbjct: 1147 NEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFH 1206
Query: 289 LVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATF 348
+V+ G+ V D +SI+V + T GLCG YNG P+DD P G LA F
Sbjct: 1207 VVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEF 1266
Query: 349 GNSW--RLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQL--LEGPFGQ 404
G SW R + GC D C ++ ++ Q +C + F +
Sbjct: 1267 GQSWVKRDTFCQVGCGDR------CPSCAKVEG-------FSKVQQLCSLIPNQNAAFSK 1313
Query: 405 CHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPG 463
CH++V+P +++ CLF C G Q C+ +Y C + I + WR
Sbjct: 1314 CHSKVNPTFFYKNCLFDSCIDG-------GAVQTACSWLQNYASTCQTQGITVTGWRNYT 1366
Query: 464 FCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAH 523
C CP Y CVS+C P C A+ + C CV GC C G NG C+
Sbjct: 1367 SCTVTCPPNSHYESCVSVCQPRCAAIRL--KSDCSHYCVEGCHCDAGYVLNGKSCILPHS 1424
Query: 524 CPCYYCRQRYVP------GDTVRQL---------CNP--------CVCRDGRWHCAQALC 560
C CY + Y P D R+ C+P C R+G C
Sbjct: 1425 CGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTK- 1483
Query: 561 PAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQ-----DYVKGQLLILLEHGACDAGSC 615
+ C G G + TFDG F C + L + QL+I + + +
Sbjct: 1484 TSYCLAAGGGVFRTFDGAFLRF--PANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTI 1541
Query: 616 LHAISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWG 675
+ + + + I + D V VNG V +P+I + + ++ P Q+ +
Sbjct: 1542 ISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYN 1601
Query: 676 LSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCP 735
V I++ R ++V GLCG F + DD++T G S A ++ G + P
Sbjct: 1602 -GFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRP 1660
Query: 736 SEDSALLSPCTTHSQRHAFAEAACAILH----------------SSVFQECHRLVDKEPF 779
L+P Q +A A C +H FQ C+ L+D PF
Sbjct: 1661 ------LAPSCNELQFSQYA-AMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPF 1713
Query: 780 YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECAP 838
Y C C LC L+AY C G S W + C + P
Sbjct: 1714 YESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKENCSGVVED--------P 1764
Query: 839 ACGQHCGKPEDCGELGSCVAGCNC 862
G C P ELG+ C C
Sbjct: 1765 CVGADC--PNRTCELGNGRELCGC 1786
Score = 157 bits (398), Expect = 2e-37
Identities = 131/491 (26%), Positives = 195/491 (39%), Gaps = 50/491 (10%)
Query: 906 ERGLWNCTARHCPSQAFCPRELVYAPG-ACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
E G W T CP + CP + C TC++ + C ++GC C G LL
Sbjct: 970 EVGPWR-TYDFCPLE--CPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALL 1026
Query: 965 DERCVPPDLCPCRHSGQWYLPNAT--IQEDCNV-CVCRG--RQWHCTG------------ 1007
+CV C C G N T + DC + C C G + HC
Sbjct: 1027 GSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEE 1086
Query: 1008 -------QRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASG-------LFTVSAQ 1053
R C SG HY+TFDG F + +C +L S F V+A+
Sbjct: 1087 GGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAK 1146
Query: 1054 NLPCGASGLTCTKALAVRLEG--TVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLF 1111
N S K + V + G V+H V VN + P +++ G
Sbjct: 1147 NEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFH 1206
Query: 1112 LLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELA 1171
+++ T GL +++D T + + + + GLCG ++G+ +DL G+L +
Sbjct: 1207 VVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEF 1266
Query: 1172 AHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQP----LFTLCHAEVPPQQHYE 1227
SW + G C G+++ + L P F+ CH++V P Y+
Sbjct: 1267 GQSWVKRDTFCQVG-CGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYK 1325
Query: 1228 WCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGP 1286
CL+D+ C GG + CS + YA C G V WR+ C++ C YE+C
Sbjct: 1326 NCLFDS--CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVS 1383
Query: 1287 TCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVL 1346
C P C + C CVEGC C G +L+G +C+ P SC C + P +
Sbjct: 1384 VCQPRCAAIRLKS--DCSHY-CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLF 1440
Query: 1347 -QKDC-GNCTC 1355
DC C C
Sbjct: 1441 WNSDCTRRCRC 1451
Score = 139 bits (350), Expect = 7e-32
Identities = 135/529 (25%), Positives = 202/529 (38%), Gaps = 58/529 (10%)
Query: 903 ICQERGL----WNCTARHCPSQAFCPRELVYA--PGACLLTCDSPSANHSCPAGSTDGCV 956
+CQ G+ W T C S CP Y+ +C TC +A+ +C T+GC
Sbjct: 574 VCQALGIPIGDWR-TQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCE 632
Query: 957 CPPGTVLLDERCVPPDLCPCRHSGQ--------WYLPNATIQEDC--------------- 993
C G VL +CVP C C G W N T+Q C
Sbjct: 633 CNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGS 692
Query: 994 -NVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL----- 1047
VC C +R + C S TFDG ++ +P Y L++
Sbjct: 693 GEVCAVEDGYQGCFPKRET-VCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLE 751
Query: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRR 1107
++ + G + L + L E + + V +NG V P + L + R
Sbjct: 752 IDINKKKPDAGPAWLRGLRILVADQE-VKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR 810
Query: 1108 AGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
+ + +T+ + + ++LS + GLCG ++ +AS++ G
Sbjct: 811 NKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
Query: 1168 AELAAHSW-RLSPLC-PEPGDLPHPCTMNTHRAGW--ARARCGALLQP---LFTLCHAEV 1220
+ SW +C E GDL C ++ + +R+RCG + P F CH V
Sbjct: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
Query: 1221 PPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV-RWRSQELCSLQCEGGQ 1279
+Y CL+ C SGG+ LC ++A YA C V WR+ + C L+C
Sbjct: 931 NVTAYYRTCLFRL--CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENS 988
Query: 1280 VYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNS 1339
+E C TC TC P V +C EGC C EG L G C+ + C C + +
Sbjct: 989 HFEEC-ITCTETCETLTLGP---ICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQ 1044
Query: 1340 FPPGSVLQKDCGNCTCQEGQWHCGGDGG-HCEELVPACAEGEALCQENG 1387
D CQ + G D HCE + C + E +E G
Sbjct: 1045 LATNETFWVD---LDCQIFCYCSGTDNRVHCETI--PCKDDEYCMEEGG 1088
Score = 130 bits (327), Expect = 3e-29
Identities = 111/419 (26%), Positives = 172/419 (41%), Gaps = 37/419 (8%)
Query: 995 VCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVRE-----ASGLFT 1049
VC +G+ ++C+ S C G PHY TFDG F + G+C YLL R+ + F+
Sbjct: 304 VCEPKGKFFYCSAVETS-TCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFS 362
Query: 1050 VSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGR--AVTVNGVSVTPPKVYTGPGLSLRR 1107
V A+N S ++ K L+V + G + + +G V VN + + P + + +
Sbjct: 363 VEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ 422
Query: 1108 AGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPT 1167
+G+ + T GL + +DG + + + GLCG+++ + +D G +
Sbjct: 423 SGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMS 482
Query: 1168 AELAAHSWRL--SPLCPEPG--DLPHPCTMNTHRAGWARARCGALLQ---PLFTLCHAEV 1220
SWR+ + + G D C T + CG L + PL+ C V
Sbjct: 483 VLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWE-CGTVV 541
Query: 1221 PPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV-RWRSQELC--SLQCEG 1277
P C+YD C G LC AI YA C G + WR+Q C ++QC
Sbjct: 542 DPTAFVHSCVYDLCSVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPS 599
Query: 1278 GQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGR 1337
Y C +CP TC + +C C EGC C +G +L C+ C C++
Sbjct: 600 FSHYSVCTSSCPDTCSDL--TASRNC-ATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDG 656
Query: 1338 NSFPPGSVLQKDCG---NCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGH--CVP 1391
+ + G C C+E GG C GE E+G+ C P
Sbjct: 657 HYYTMGEFFWATANCTVQCLCEE--------GGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
Score = 123 bits (308), Expect = 5e-27
Identities = 120/452 (26%), Positives = 173/452 (38%), Gaps = 60/452 (13%)
Query: 511 LFWNGTLCVPAAHCPCY----YCRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAV 566
+FW+ C C + YC++ + ++C P G++ A+ + C V
Sbjct: 272 VFWDDLNCTVKCRCLDFNNEIYCQEASC---SPYEVCEP----KGKFFYCSAVETSTCVV 324
Query: 567 GGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL------EHGACDAGSCLHAIS 620
G+ HY TFDG + F G C Y L + ++ L EH A S + +S
Sbjct: 325 FGEPHYHTFDGFLFHFQG--SCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELS 382
Query: 621 VSLEDTHIQLRDS--GAVLVNG--------QDVGLPWIGAEGLSVRRASSAFLLLRWPGA 670
V + I + G V VN D+G I G+S + LL+ + G
Sbjct: 383 VEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDG- 441
Query: 671 QVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQV-A 729
Q +S P +YI + GLCG + +N DDFL P G S+ ++V
Sbjct: 442 QHYASISVPGSYI-------NSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYH 494
Query: 730 GKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAV 787
+C S + C ++ F C L+ + EC +VD F C+ +
Sbjct: 495 ADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDL 554
Query: 788 CGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLC--PVMCPGGQEYRECAPACGQHC 844
C LC + AYA C G WR QT C V CP Y C +C
Sbjct: 555 CSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC---- 610
Query: 845 GKPEDCGELGS-------CVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGS---A 894
P+ C +L + C GC C G + QCVP C C Y G A
Sbjct: 611 --PDTCSDLTASRNCATPCTEGCECNQGFVLS-TSQCVPLHKCGCDFDGHYYTMGEFFWA 667
Query: 895 TMKECNRCICQERGLWNCTARHCPSQAFCPRE 926
T +C+C+E G C + C S C E
Sbjct: 668 TANCTVQCLCEEGGDVYCFNKTCGSGEVCAVE 699
Score = 105 bits (263), Expect = 9e-22
Identities = 112/451 (24%), Positives = 176/451 (39%), Gaps = 58/451 (12%)
Query: 904 CQERGLWNCTARHCPS-QAFCPRELVYAP--GACLLTCDSPSANHSCPAGSTDGCVCPPG 960
CQ +G+ R+ S CP Y C C + C +GC C G
Sbjct: 1352 CQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAG 1411
Query: 961 TVLLDERCVPPDLCPCRHSGQWYLPNATI-QEDC---------NVCVCRGRQWHCTGQ-- 1008
VL + C+ P C C G++Y P DC NV C RQ +
Sbjct: 1412 YVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECA 1471
Query: 1009 ----------RRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNL--- 1055
++ C A+G + TFDG +P C ++L L +S Q +
Sbjct: 1472 LRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINF 1531
Query: 1056 -PCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLL 1114
A LT + + + + V VNG V P + TG + + FL++
Sbjct: 1532 DKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFI-TGLATKIYSSEGFLVI 1590
Query: 1115 STHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHS 1174
T + + ++G + + +S + + +V GLCG+F+GD ++D + +G ++ + A S
Sbjct: 1591 DTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQS 1650
Query: 1175 WRLS-----PLCPEPGDLPHP-----CTMNTHRAGWARARCGAL--LQPLFTLCHAEVPP 1222
W+ + PL P +L C + C L ++ F C+ + P
Sbjct: 1651 WKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDP 1710
Query: 1223 QQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHG-HHVRWRSQELCSLQCEGGQVY 1281
YE C D GC S + LC ++A Y + C G W +E CS G V
Sbjct: 1711 LPFYESCYLD--GCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKENCS-----GVVE 1762
Query: 1282 EAC-GPTCP-PTCHEQHPEPGWHCQVVACVE 1310
+ C G CP TC E G ++ C+E
Sbjct: 1763 DPCVGADCPNRTC-----ELGNGRELCGCIE 1788
Score = 60.1 bits (144), Expect = 6e-08
Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSF-LLG 2693
CP +C D A+R+C+ C EGC C G +L ++C+PL +C C G F
Sbjct: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
Query: 2694 NCS-QCVCEKG 2703
NC+ QC+CE+G
Sbjct: 670 NCTVQCLCEEG 680
Score = 58.2 bits (139), Expect = 2e-07
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 4/98 (4%)
Query: 3090 CPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
CP + C P +C++L+A R C GC C G +L + CVP C C +G
Sbjct: 597 CPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDG 656
Query: 3149 HLYPPGS---TVVRPCENCSCVSGLIANCSSWPCAEGE 3183
H Y G C C G C + C GE
Sbjct: 657 HYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGE 694
Score = 54.7 bits (130), Expect = 2e-06
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 7/104 (6%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTD 4121
CP+ C + CP CSDL C C +GC C +G + CVP+ C C D
Sbjct: 597 CPSFSHYSVCTSSCPDTCSDLTASRNCATP--CTEGCECNQGFVLSTSQCVPLHKCGC-D 653
Query: 4122 AQGHSWAPGSQHQDACN---NCSC-QAGQLSCTAQPCPPPTHCA 4161
GH + G N C C + G + C + C CA
Sbjct: 654 FDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCA 697
Score = 52.4 bits (124), Expect = 1e-05
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 23/195 (11%)
Query: 1759 WSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNAT-CSGELM 1817
+ +CS GT+ C + Q C AL + R Q GC + C
Sbjct: 552 YDLCSVRDNGTLL----CQAIQAYALVCQALGIPIGDWRT-----QTGCVSTVQCPSFSH 602
Query: 1818 FQPC-APCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGAR 1876
+ C + CP TC D++ C PC + GC C +G VL S CV +C C DG
Sbjct: 603 YSVCTSSCPDTCSDLTASRNCAT--PC-TEGCECNQGFVL-STSQCVPLHKCGCDFDGHY 658
Query: 1877 YWPGQRI--KADCQL-CICQDGRP-----RRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQ 1928
Y G+ A+C + C+C++G + C CAV+ G+ P + +
Sbjct: 659 YTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQN 718
Query: 1929 SIQWSFRSSNNPRPS 1943
+ +F ++ PS
Sbjct: 719 QVLHTFDGASYAFPS 733
Score = 52.0 bits (123), Expect = 2e-05
Identities = 36/131 (27%), Positives = 51/131 (38%), Gaps = 12/131 (9%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
C S+A + C + T C +CPEN F E+C C C T G
Sbjct: 954 CDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF---EECIT----CTETCETLTLG 1006
Query: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLD-SCN---NCTCV 2971
C C+ GC C G L + C+ RS+C C G A+ +D C C+
Sbjct: 1007 PICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGT 1066
Query: 2972 SGKMACTSERC 2982
++ C + C
Sbjct: 1067 DNRVHCETIPC 1077
Score = 49.3 bits (116), Expect = 1e-04
Identities = 29/101 (28%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Query: 3087 PGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAH 3146
P CP + + +C +C L+ +C GC C G LL + CV +C C
Sbjct: 981 PLECPENSHFEECITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNF 1040
Query: 3147 EGHLYPPGST--VVRPCENCSCVSGL--IANCSSWPCAEGE 3183
EGH T V C+ SG +C + PC + E
Sbjct: 1041 EGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDE 1081
Score = 49.3 bits (116), Expect = 1e-04
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 17/124 (13%)
Query: 2632 VPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
V C P C + CS +CVEGC C G +L+ C+ C C + P F
Sbjct: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
Query: 2692 LGNCS-QCVC-EKGELLCQPGGCPLPCGWSAWSSWAPCDRSCG--SGVRARFRSPSNPPA 2747
+C+ +C C + + C P C D C +GVR F + ++
Sbjct: 1442 NSDCTRRCRCFRRNVIQCDPRQC-------------KSDEECALRNGVRGCFSTKTSYCL 1488
Query: 2748 AWGG 2751
A GG
Sbjct: 1489 AAGG 1492
Score = 48.9 bits (115), Expect = 1e-04
Identities = 38/120 (31%), Positives = 48/120 (40%), Gaps = 18/120 (15%)
Query: 3291 CEGPRAQGEVCQALPCPV------TNCTAI----EGAEYSPCGPPCPRSCDDLV---HCV 3337
C+ +A VCQAL P+ T C + + YS C CP +C DL +C
Sbjct: 565 CQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCA 624
Query: 3338 WRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCN-HCTCLEG 3396
C GC C G VLS++ CV C C G + G C C C EG
Sbjct: 625 TPCTEGCECNQGFVLSTSQ--CVPLHKCGC--DFDGHYYTMGEFFWATANCTVQCLCEEG 680
Score = 48.5 bits (114), Expect = 2e-04
Identities = 36/140 (25%), Positives = 51/140 (36%), Gaps = 7/140 (5%)
Query: 4586 GRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
G + G + PL + DP A SC + L C V +G + +A AL
Sbjct: 520 GSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDL------CSVRDNGTLLCQAIQAYAL 573
Query: 4646 CGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
P G + C + CP +C+DL C PC GC
Sbjct: 574 VCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCAT-PCTEGCE 632
Query: 4706 CPPGQLVQDGRCVPISSCRC 4725
C G ++ +CVP+ C C
Sbjct: 633 CNQGFVLSTSQCVPLHKCGC 652
Score = 48.5 bits (114), Expect = 2e-04
Identities = 45/177 (25%), Positives = 62/177 (35%), Gaps = 23/177 (12%)
Query: 2848 GGIQTRGRSCSSLAPGDTTCPGPH-SQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCP 2906
G +QT +CS L +TC + T N CT CP N + S C
Sbjct: 1336 GAVQT---ACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV------CQ 1386
Query: 2907 RLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC- 2965
C +C+ +C GC C G L+ SC+ C C G+ Y + C
Sbjct: 1387 PRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCT 1446
Query: 2966 NNCTCV-SGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGG 3021
C C + C +C S C+ G+R F T+ A GG
Sbjct: 1447 RRCRCFRRNVIQCDPRQCK-----------SDEECALRNGVRGCFSTKTSYCLAAGG 1492
Score = 47.4 bits (111), Expect = 4e-04
Identities = 29/103 (28%), Positives = 36/103 (34%), Gaps = 9/103 (8%)
Query: 2883 TAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPR 2942
T QCP F C CP C C C GC C G L + C+P
Sbjct: 594 TVQCPS---FSHYSVCTSS---CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
Query: 2943 SQCPCQLHGQLYASGAM--ARLDSCNNCTC-VSGKMACTSERC 2982
+C C G Y G A + C C G + C ++ C
Sbjct: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTC 690
Score = 46.2 bits (108), Expect = 8e-04
Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 14/107 (13%)
Query: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQ 4876
+CP S C +SCP C L C PC GC C G +L CVP C C
Sbjct: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCAT-PCTEGCECNQGFVLSTSQCVPLHKCGCDF 654
Query: 4877 HSLPWGLTLTLEEQAQELPPGTVLTRNCT-RCVC-HGGAFSCSLVDC 4921
G T+ E T NCT +C+C GG C C
Sbjct: 655 D----GHYYTMGEFFW-------ATANCTVQCLCEEGGDVYCFNKTC 690
Score = 44.7 bits (104), Expect = 0.002
Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 11/109 (10%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
C CP C C C L G +C D C +GC+C +G CV C
Sbjct: 980 CPLECPENSHFEECIT-CTETCETLTLGPICVDS--CSEGCQCDEGYALLGSQCVTRSEC 1036
Query: 4118 DCTDAQGHSWAPGSQH------QDACNNCSCQAGQLSCTAQPCPPPTHC 4160
C + +GH A Q C CS ++ C PC +C
Sbjct: 1037 GC-NFEGHQLATNETFWVDLDCQIFC-YCSGTDNRVHCETIPCKDDEYC 1083
Score = 43.5 bits (101), Expect = 0.005
Identities = 30/116 (25%), Positives = 41/116 (35%), Gaps = 13/116 (11%)
Query: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNC-- 4480
C + C S C C+ + + C PC GC C +G + C+P +C C
Sbjct: 597 CPSFSHYSVCTSSCPDTCSDLTASRNCAT--PCTEGCECNQGFVLSTSQCVPLHKCGCDF 654
Query: 4481 -WHTSAAGAGMTLAPGDRLQLGCKE-----C---ECRRGELHCTSQGCQGLLPLSE 4527
H G +Q C+E C C GE+ G QG P E
Sbjct: 655 DGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRE 710
Score = 43.1 bits (100), Expect = 0.007
Identities = 23/97 (23%), Positives = 32/97 (32%), Gaps = 3/97 (3%)
Query: 3090 CPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
CP + + C CA + + C GCHC +G +L C+ C C +G
Sbjct: 1372 CPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDG 1431
Query: 3149 HLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEGE 3183
Y P C C + C C E
Sbjct: 1432 KYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDE 1468
Score = 42.7 bits (99), Expect = 0.009
Identities = 25/110 (22%), Positives = 40/110 (36%), Gaps = 4/110 (3%)
Query: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
N C CP +C + C RC+ ++ C C +GC C G + C+
Sbjct: 1364 NYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCS--HYCVEGCHCDAGYVLNGKSCIL 1421
Query: 4114 IGHCDC-TDAQGHSWAPGSQHQDACNNCSC-QAGQLSCTAQPCPPPTHCA 4161
C C +D + + + D C C + + C + C CA
Sbjct: 1422 PHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECA 1471
Score = 42.4 bits (98), Expect = 0.012
Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 3/77 (3%)
Query: 4799 CQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPG 4857
C+ D E CP ECP C T C C L G ICV + C GC C
Sbjct: 964 CKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICV-DSCSEGCQCDE 1021
Query: 4858 GQLLHNGTCVPPTACPC 4874
G L CV + C C
Sbjct: 1022 GYALLGSQCVTRSECGC 1038
Score = 42.4 bits (98), Expect = 0.012
Identities = 41/147 (27%), Positives = 54/147 (36%), Gaps = 18/147 (12%)
Query: 1773 QRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDI 1831
Q C QN TC + R C TC ++ C C C I
Sbjct: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSC------TVTCPPNSHYESCVSVCQPRCAAI 1392
Query: 1832 SGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRI-KADC-QL 1889
+ C C GC C G VL + C+ P C C DG Y P Q +DC +
Sbjct: 1393 RLKSDC--SHYCVE-GCHCDAGYVLNGKS-CILPHSCGCYSDGKYYEPKQLFWNSDCTRR 1448
Query: 1890 CICQDGR-----PRRCRLNPDCAVDCG 1911
C C PR+C+ + +CA+ G
Sbjct: 1449 CRCFRRNVIQCDPRQCKSDEECALRNG 1475
Score = 41.6 bits (96), Expect = 0.021
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
Query: 4799 CQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPG 4857
CQ Q N C CPP +C + C C ++ + C C GC C
Sbjct: 1352 CQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC-SHYCVEGCHCDA 1410
Query: 4858 GQLLHNGTCVPPTACPC 4874
G +L+ +C+ P +C C
Sbjct: 1411 GYVLNGKSCILPHSCGC 1427
Score = 40.8 bits (94), Expect = 0.035
Identities = 28/103 (27%), Positives = 36/103 (34%), Gaps = 10/103 (9%)
Query: 3309 TNCTAI--EGAEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPG 3363
T+CT + Y C C C + C C GC+C G VL NG C+ P
Sbjct: 1366 TSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVL--NGKSCILPH 1423
Query: 3364 HCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPC 3405
C C G+ + P D C C + C C
Sbjct: 1424 SCGCYS--DGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQC 1464
Score = 40.4 bits (93), Expect = 0.046
Identities = 27/102 (26%), Positives = 37/102 (36%), Gaps = 10/102 (9%)
Query: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481
+C P + +C S C CA C C GC+C G + CI P C C+
Sbjct: 1371 TCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CVEGCHCDAGYVLNGKSCILPHSCGCY 1428
Query: 4482 HTSAAGAGMTLAPGDRL-QLGC-KECEC-RRGELHCTSQGCQ 4520
G P C + C C RR + C + C+
Sbjct: 1429 -----SDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCK 1465
Score = 38.9 bits (89), Expect = 0.13
Identities = 32/123 (26%), Positives = 48/123 (39%), Gaps = 16/123 (13%)
Query: 4915 SCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQ 4974
SC+ V C PP ++ + +C+ C A + +S+CS GC C G+ +
Sbjct: 1367 SCT-VTC--PPNSHYESC----VSVCQPRCA---AIRLKSDCSHYCVEGCHCDAGYVLN- 1415
Query: 4975 AGPCVPEDHCECWHLGRPHLPGS-EWQEAC-ESCLCLSGRPVCTQHCSPLTCAQGEEMVL 5032
C+ C C+ G+ + P W C C C + C P C EE L
Sbjct: 1416 GKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVI---QCDPRQCKSDEECAL 1472
Query: 5033 EPG 5035
G
Sbjct: 1473 RNG 1475
Score = 38.1 bits (87), Expect = 0.23
Identities = 52/200 (26%), Positives = 70/200 (35%), Gaps = 44/200 (22%)
Query: 4606 CPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCP 4665
C D GA +C W L S CQ G WR + C C ESC P
Sbjct: 1332 CIDGGAVQTACSW-LQNYASTCQT--QGITVTGWRNYTS-CTVTCPPNSHYESCVSVCQP 1387
Query: 4666 ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC 4725
C A + + C H C + GC C G ++ C+ SC C
Sbjct: 1388 RCAA------IRLKSDCSHYCVE--------------GCHCDAGYVLNGKSCILPHSCGC 1427
Query: 4726 GLPSANASWELAPAQAV-QLDC-QNCTCVNESLV-CPHQECP----------VLGPWSAW 4772
S +E P Q DC + C C +++ C ++C V G +S
Sbjct: 1428 --YSDGKYYE--PKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTK 1483
Query: 4773 SSCSAPCGGGTMERHRTCEG 4792
+S GGG RT +G
Sbjct: 1484 TSYCLAAGGGVF---RTFDG 1500
Score = 37.0 bits (84), Expect = 0.51
Identities = 33/125 (26%), Positives = 48/125 (38%), Gaps = 31/125 (24%)
Query: 3293 GPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPG 3349
GP + C L CP E + + C C +C+ L CV C GC C G
Sbjct: 972 GPWRTYDFCP-LECP-------ENSHFEEC-ITCTETCETLTLGPICVDSCSEGCQCDEG 1022
Query: 3350 QVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPD------GCN---HCTCLEGRLNC 3400
L G+ CV C C + G +LA + C +C+ + R++C
Sbjct: 1023 YALL--GSQCVTRSECGC--------NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC 1072
Query: 3401 TDLPC 3405
+PC
Sbjct: 1073 ETIPC 1077
Score = 36.2 bits (82), Expect = 0.87
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPC 2677
C +C C C EGC+C G L ++C+ SEC C
Sbjct: 996 CTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGC 1038
Score = 35.4 bits (80), Expect = 1.5
Identities = 18/70 (25%), Positives = 23/70 (32%), Gaps = 3/70 (4%)
Query: 3520 QENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLC 3579
Q C C CP +C DL+ C + C C C G + C
Sbjct: 588 QTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNC---ATPCTEGCECNQGFVLSTSQC 644
Query: 3580 VPPAHCRCQY 3589
VP C C +
Sbjct: 645 VPLHKCGCDF 654
Score = 35.4 bits (80), Expect = 1.5
Identities = 22/84 (26%), Positives = 28/84 (33%), Gaps = 3/84 (3%)
Query: 4397 ARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQ 4456
AR + C D P + C F C + C C T +C D C
Sbjct: 958 ARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLGPICVD--SCS 1014
Query: 4457 PGCYCPKGLLEQAGGCIPPEECNC 4480
GC C +G C+ EC C
Sbjct: 1015 EGCQCDEGYALLGSQCVTRSECGC 1038
Score = 35.0 bits (79), Expect = 1.9
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--QECPC 3753
CP+ Y C CP +C+ +T C + C EGC C +G CV +C C
Sbjct: 597 CPSFSHYSVCT--SSCPDTCSDLTASRNCATP-CTEGCECNQGFVLSTSQCVPLHKCGC 652
Score = 34.7 bits (78), Expect = 2.5
Identities = 34/129 (26%), Positives = 45/129 (34%), Gaps = 20/129 (15%)
Query: 4632 SGGFRLRWREAEALCGGGCRE------PWAQESCNGGPCPECEAQDTVFTLDCANQCPHS 4685
SGG ++ A C+ PW CPE + T C +
Sbjct: 946 SGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT------CTET 999
Query: 4686 CADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQA--VQ 4743
C L C+ C GC+C G + +CV S C C +LA + V
Sbjct: 1000 CETLTLGPICVDS-CSEGCQCDEGYALLGSQCVTRSECGCNF----EGHQLATNETFWVD 1054
Query: 4744 LDCQ-NCTC 4751
LDCQ C C
Sbjct: 1055 LDCQIFCYC 1063
Score = 34.7 bits (78), Expect = 2.5
Identities = 25/89 (28%), Positives = 31/89 (34%), Gaps = 15/89 (16%)
Query: 3677 CPGPARQSRTCSTQVCREAG----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
C + TC TQ G CP Y C C CA + + C
Sbjct: 1342 CSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCV--SVCQPRCAAIRLKSDC- 1398
Query: 3727 SEGCEEGCHCPEGTFQHRLACV--QECPC 3753
S C EGCHC G + +C+ C C
Sbjct: 1399 SHYCVEGCHCDAGYVLNGKSCILPHSCGC 1427
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 208 bits (530), Expect = 1e-52
Identities = 122/386 (31%), Positives = 170/386 (44%), Gaps = 61/386 (15%)
Query: 2506 WSVWSSCSRSCGLGLTFQRQELLRPPLP---GGSCPRDRFRSQSCFVQACPVAGAWAMWE 2562
WS W +CS +CG G+ +R L PLP G C ++C + CPV G+W+ W
Sbjct: 4535 WSAWRACSVTCGKGIQ-KRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSEWS 4593
Query: 2563 AWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYV 2622
W C+ SCG G+Q+R R+C +P ++GG PC G + E C ++P C + +
Sbjct: 4594 LWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRP------CPVHGAW- 4646
Query: 2623 SADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEE 2682
S P +CS C +G + L + S C G E
Sbjct: 4647 ---------------SAWQPWG--TCSESCGKGTQTRARLCNNPPPAFGGSYCD---GAE 4686
Query: 2683 LKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSP 2742
+ +C CP+ W+ W+SW+ C SCG G R R R
Sbjct: 4687 TQMQ-------------------VCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGC 4727
Query: 2743 SNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSR 2802
S+P +GG CEG + C++ W+PW+ W +CS++C G R R
Sbjct: 4728 SDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTC-----NGGQMRRYR 4782
Query: 2803 LC----PSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCS 2858
C PS G +C G +Q + C+ +CPV WG W WS CSA C GG +TR R C
Sbjct: 4783 TCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCD 4842
Query: 2859 SLAP--GDTTCPGPHSQTRDCNTQPC 2882
P G CPG +Q CN Q C
Sbjct: 4843 HPVPVKGGRPCPGDTTQVTRCNVQAC 4868
Score = 192 bits (487), Expect = 9e-48
Identities = 143/459 (31%), Positives = 182/459 (39%), Gaps = 103/459 (22%)
Query: 3857 DLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCT 3916
+ EC + + G+ V + + GG+ WS+W CS +C + R+RLC
Sbjct: 4506 EFECVARNLMGSVLVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQ----KRSRLCNQPLP 4561
Query: 3917 M--GDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYR 3974
G P Q + +C P CP G SW+ W+ WE C+RSCG G Q R R
Sbjct: 4562 ANGGKPCQGSDLEMRNCQNKP-CPVDG------SWSEWSLWEECTRSCGRGNQTRTRTCN 4614
Query: 3975 PPG--PGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCS 4032
P GG C E CN+R CPV G WS W PW C SCG G R+R C+
Sbjct: 4615 NPSVQHGGRPCEGNAV---EIIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARLCN 4671
Query: 4033 SPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCA--NRCPRRCSDLQEGIVCQD 4090
+PP GG+ C G Q ++CN E CP + T A + C C
Sbjct: 4672 NPPPAFGGSYCDGAETQMQVCN----ERNCPIHGKWATWASWSACSVSCGG--------G 4719
Query: 4091 DQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCT 4150
+ +GC P + Q GG C+ +D Q D CN+ C
Sbjct: 4720 ARQRTRGCSDP---VPQYGG----RKCEGSDVQ----------SDFCNSDPC-------- 4754
Query: 4151 AQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPS 4210
PTH WS WS W CS +C GQ R+R+ C P
Sbjct: 4755 ------PTHGNWSPWSGWGTCSRTCN-GGQMRRYRT-------------------CDNP- 4787
Query: 4211 CPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCG 4270
PP G R+ DS +Q C C V +W W SWS C SCG
Sbjct: 4788 -PP--SNGGRACGGPDSQIQR-------------CNTDMCPVDGSWGSWHSWSQCSASCG 4831
Query: 4271 GGNQVRTRACRAAAPHHRSPPCLGPDTQTRQ---QPCPG 4306
GG + R R C P PC G TQ + Q CPG
Sbjct: 4832 GGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPG 4870
Score = 187 bits (474), Expect = 3e-46
Identities = 112/337 (33%), Positives = 143/337 (42%), Gaps = 61/337 (18%)
Query: 2554 VAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGT 2613
V G ++ W AW CSV+CG G Q R R C P P NGG PC G+ E C +PC
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP--- 4584
Query: 2614 DCELGRVYVSADLCQKGLVPPCPPSCL--DPKANRSCSGHCVEGCRCPPGLLLHDTRCLP 2671
V + L C SC + R+C+ V+ H R
Sbjct: 4585 --------VDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQ----------HGGR--- 4623
Query: 2672 LSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSC 2731
PC GN + + +C CP+ WSAW W C SC
Sbjct: 4624 ----PCE--------------GNAVEII------MCNIRPCPVHGAWSAWQPWGTCSESC 4659
Query: 2732 GSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAP 2791
G G + R R +NPP A+GG+ C+G ++Q C+ W W SWS+CS SC
Sbjct: 4660 GKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSC--- 4716
Query: 2792 GGGPGWRSRSRLCPSP----GDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCD 2847
G G R R+R C P G C G Q + C+ CP W W+ W TCS C+
Sbjct: 4717 --GGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCN 4774
Query: 2848 GGIQTRGRSCSSLAP--GDTTCPGPHSQTRDCNTQPC 2882
GG R R+C + P G C GP SQ + CNT C
Sbjct: 4775 GGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMC 4811
Score = 186 bits (473), Expect = 4e-46
Identities = 109/341 (31%), Positives = 143/341 (41%), Gaps = 54/341 (15%)
Query: 2707 CQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHT 2766
CQ CP+ WS WS W C RSCG G + R R+ +NP GG PCEG+ E+ C+
Sbjct: 4578 CQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNI 4637
Query: 2767 VCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSP----GDSSCPGDATQEEPC 2822
W+ W W +CS+SC G G ++R+RLC +P G S C G TQ + C
Sbjct: 4638 RPCPVHGAWSAWQPWGTCSESC-----GKGTQTRARLCNNPPPAFGGSYCDGAETQMQVC 4692
Query: 2823 SPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAP--GDTTCPGPHSQTRDCNTQ 2880
+ CP+ W WA WS CS C GG + R R CS P G C G Q+ CN+
Sbjct: 4693 NERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSD 4752
Query: 2881 PCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCL 2940
PC T G +G+ TC G +C
Sbjct: 4753 PCP---------------------------THGNWSPWSGWGTCSRTCNGGQMRRYRTC- 4784
Query: 2941 PRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCS 3000
P +G G +++ CN ++ CPV W W WS CS S
Sbjct: 4785 ---DNPPPSNGGRACGGPDSQIQRCN------------TDMCPVDGSWGSWHSWSQCSAS 4829
Query: 3001 CNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPG 3041
C G + R R P GG C G T + C+++ CPG
Sbjct: 4830 CGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPG 4870
Score = 185 bits (470), Expect = 9e-46
Identities = 120/376 (31%), Positives = 151/376 (40%), Gaps = 72/376 (19%)
Query: 3159 RPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVP 3218
+PC+ + NC + PC + +WS W+ W +C+ SCG R R C +PS V
Sbjct: 4566 KPCQGSDLE---MRNCQNKPCPV-DGSWSEWSLWEECTRSCGRGNQTRTRTC-NNPS-VQ 4619
Query: 3219 STVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRA 3278
P C G E C ++ C G W W PW CS SCG G ++R R
Sbjct: 4620 HGGRP----------CEGNAVEIIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARL 4669
Query: 3279 CDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW 3338
C+ PPP G YC+G Q +VC CP+ A A +S C C
Sbjct: 4670 CNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWAT-WASWSACSVSCGGGARQRTR--- 4725
Query: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
GC P Q G R G+ + + D CN
Sbjct: 4726 ----GCSDPVPQY---------------------GGRKCEGSDV-QSDFCNSD------- 4752
Query: 3399 NCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQH 3458
PCP G W PWS W CS+ C G R R C P P +GG C G
Sbjct: 4753 -----PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC------GGPDS 4801
Query: 3459 QREACPSYATCPVDGAWGPWGPWSPCDMCL--GQSHRSRACSRPPTPEGGRPCPGNHTQS 3516
Q + C + CPVDG+WG W WS C G+ R R C P +GGRPCPG+ TQ
Sbjct: 4802 QIQRC-NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQV 4860
Query: 3517 RPCQENSTQCTDCGGG 3532
C + C GG
Sbjct: 4861 TRCNVQA-----CPGG 4871
Score = 181 bits (460), Expect = 1e-44
Identities = 135/432 (31%), Positives = 166/432 (38%), Gaps = 106/432 (24%)
Query: 3646 GVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRE 3705
G +S W W CSV+CG G Q RSR C +P PA + C R
Sbjct: 4530 GGFSQWSAWRACSVTCGKGIQKRSRLCNQPL---PANGGKPCQGSDLE---------MRN 4577
Query: 3706 CQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGA 3765
CQ + CP G +SE W L E
Sbjct: 4578 CQ-NKPCPVD--------GSWSE-----------------------------WSLWE--- 4596
Query: 3766 TIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGK----------LSCSLDDCFEADGGFG 3815
+ + G G+ QT +C N S HG + C++ C G +
Sbjct: 4597 ---ECTRSCGRGN-----QTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPC-PVHGAWS 4647
Query: 3816 PWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLE-CPSPDCPGAEGSTVE 3874
W PWG CS SCG GT+TR+R C P G C G ++ C +CP
Sbjct: 4648 AWQPWGTCSESCGK-GTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP-------- 4698
Query: 3875 PVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTMGDPLQE---RPCNLPSC 3931
+ G W W+SWS CS SC AR RTR C DP+ + R C S
Sbjct: 4699 ----IHGKWATWASWSACSVSCGGGAR----QRTRGC------SDPVPQYGGRKCE-GSD 4743
Query: 3932 TELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYR--PPGPGGHWCPNILTA 3989
+ C C +W+ W+ W CSR+C GQ RR R PP GG C +
Sbjct: 4744 VQSDFCNSDPCPTHG-NWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQ 4802
Query: 3990 YQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQ 4049
Q CN CPV G W W WS C SCGGG+ R R C P GG PC G+ Q
Sbjct: 4803 IQR---CNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQ 4859
Query: 4050 ARLCNPMPCEAG 4061
CN C G
Sbjct: 4860 VTRCNVQACPGG 4871
Score = 174 bits (441), Expect = 2e-42
Identities = 128/416 (30%), Positives = 164/416 (39%), Gaps = 85/416 (20%)
Query: 3809 EADGGFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLE---CPSPDC 3865
+ GGF WS W CS +C G G + RSR C +P G+ C+G DLE C + C
Sbjct: 4527 QVHGGFSQWSAWRACSVTC-GKGIQKRSRLCNQPLPANGGKPCQG--SDLEMRNCQNKPC 4583
Query: 3866 PGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTM--GDPLQE 3923
P + G W WS W C+RSC ++RTR C G P +
Sbjct: 4584 P------------VDGSWSEWSLWEECTRSC----GRGNQTRTRTCNNPSVQHGGRPCEG 4627
Query: 3924 RPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYR--PPGPGGH 3981
+ C P CP G +W++W PW CS SCG G Q R R PP GG
Sbjct: 4628 NAVEIIMCNIRP-CPVHG------AWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGS 4680
Query: 3982 WCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGA 4041
+C T Q CN R CP+ G W+ W+ WS C SCGGG R+R CS P + GG
Sbjct: 4681 YCDGAETQMQ---VCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGR 4737
Query: 4042 PCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCS--DLQEGIVCQDDQVCQKGCR 4099
C G Q+ CN PC + C R C+ ++ C + G
Sbjct: 4738 KCEGSDVQSDFCNSDPCPT--HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRA 4795
Query: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTH 4159
C GG P SQ Q CN C P
Sbjct: 4796 C--------GG------------------PDSQIQ-RCNTDMC--------------PVD 4814
Query: 4160 CAWSHWSAWSPCSHSCGPRGQQSRFR---SSTSGSWAPECREEQSQSQPCPQPSCP 4212
+W W +WS CS SCG G+++R R C + +Q C +CP
Sbjct: 4815 GSWGSWHSWSQCSASCG-GGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACP 4869
Score = 172 bits (436), Expect = 8e-42
Identities = 112/385 (29%), Positives = 149/385 (38%), Gaps = 75/385 (19%)
Query: 2456 GLPASRALCSPSQLSCGSGECLSAE---RRCDLRPDCQDGSDEDGCVDCVLAPWSVWSSC 2512
G+ LC+ + G C ++ R C +P DGS + WS+W C
Sbjct: 4548 GIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSE---------WSLWEEC 4598
Query: 2513 SRSCGLGLTFQRQELLRPPLPGGS--CPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVS 2570
+RSCG G + + P + G C + C ++ CPV GAW+ W+ WG CS S
Sbjct: 4599 TRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQPWGTCSES 4658
Query: 2571 CGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKG 2630
CG G Q+R R C +PPP GG+ C GA + C + C + + + G
Sbjct: 4659 CGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGG 4718
Query: 2631 LVPPCPPSCLDP---KANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPG 2687
C DP R C G V+ C + PC
Sbjct: 4719 GARQRTRGCSDPVPQYGGRKCEGSDVQSDFC--------------NSDPC---------- 4754
Query: 2688 VSFLLGNCSQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPA 2747
P WS WS W C R+C G R+R+ NPP
Sbjct: 4755 -------------------------PTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPP 4789
Query: 2748 AWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSP 2807
+ GG C G ++Q C+T W W SWS CS SC G G ++R RLC P
Sbjct: 4790 SNGGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASC-----GGGEKTRKRLCDHP 4844
Query: 2808 ----GDSSCPGDATQEEPCSPPVCP 2828
G CPGD TQ C+ CP
Sbjct: 4845 VPVKGGRPCPGDTTQVTRCNVQACP 4869
Score = 169 bits (429), Expect = 5e-41
Identities = 133/436 (30%), Positives = 167/436 (38%), Gaps = 108/436 (24%)
Query: 3041 GPGGEWGPWSPCSVPCGGGYRNRTRGSSRSL------------MEFSTCGLQPCAGPVPG 3088
G +W W CSV CG G + R+R ++ L +E C +PC PV G
Sbjct: 4530 GGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPC--PVDG 4587
Query: 3089 MCPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
W +C + S RG NQT C+ PS H G
Sbjct: 4588 SWSEWSLWEECTR--------SCGRG-NQTRTRTCNNPS----------------VQHGG 4622
Query: 3149 HLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHR 3208
RPCE + I C+ PC WS W PW CS SCG R R
Sbjct: 4623 ----------RPCEGNAVE---IIMCNIRPCPV-HGAWSAWQPWGTCSESCGKGTQTRAR 4668
Query: 3209 FCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSC 3268
C P PA C G E + + C + C G W W WS CS SC
Sbjct: 4669 LCNNPP------------PAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSC 4716
Query: 3269 GGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPR 3328
GGG R RTR C P PQ G CEG Q + C + PCP T + +S G C R
Sbjct: 4717 GGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP----THGNWSPWSGWG-TCSR 4771
Query: 3329 SCDDLVHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGC 3388
+C+ +R C PP S+ G C P +++ R C
Sbjct: 4772 TCNGGQMRRYRT---CDNPPP---SNGGRAC----------------GGPDSQIQR---C 4806
Query: 3389 NHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCT 3448
N TD+ CPV G W W W+ CS C G ++R R C P P GG PC
Sbjct: 4807 N-----------TDM-CPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCP 4854
Query: 3449 GEAGEAGAQHQREACP 3464
G+ + + +ACP
Sbjct: 4855 GDTTQV-TRCNVQACP 4869
Score = 156 bits (394), Expect = 6e-37
Identities = 103/339 (30%), Positives = 136/339 (40%), Gaps = 68/339 (20%)
Query: 2774 GWTPWTSWSSCSQSCLAPGGGPGWRSRSRLC----PSPGDSSCPGDATQEEPCSPPVCPV 2829
G++ W++W +CS +C G G + RSRLC P+ G C G + C CPV
Sbjct: 4531 GFSQWSAWRACSVTC-----GKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 2830 PSIWGLWAPWSTCSAPCDGGIQTRGRSCS--SLAPGDTTCPGPHSQTRDCNTQPCTAQCP 2887
W W+ W C+ C G QTR R+C+ S+ G C G + CN +PC
Sbjct: 4586 DGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVH-- 4643
Query: 2888 ENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPC 2947
A Q G C C G G + A C PP F
Sbjct: 4644 ------GAWSAWQPWGTCSESC---GKGTQTR---ARLCNNPPPAF-------------- 4677
Query: 2948 QLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVGIRR 3007
G Y GA ++ CN CP+ W+ W WS CS SC G R+
Sbjct: 4678 ---GGSYCDGAETQMQVCNE------------RNCPIHGKWATWASWSACSVSCGGGARQ 4722
Query: 3008 RFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGPWS---PCSVPCGGGYRNRT 3064
R R + P +GG +C+G ++++FC+ PCP G W PWS CS C GG R
Sbjct: 4723 RTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP-THGNWSPWSGWGTCSRTCNGGQMRRY 4781
Query: 3065 RGSSRSLMEFSTCGLQPCAGP-------VPGMCPRDKQW 3096
R + G + C GP MCP D W
Sbjct: 4782 RTCDNPP---PSNGGRACGGPDSQIQRCNTDMCPVDGSW 4817
Score = 156 bits (394), Expect = 6e-37
Identities = 104/335 (31%), Positives = 124/335 (37%), Gaps = 84/335 (25%)
Query: 3399 NCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQH 3458
NC + PCPV G W WS W C++ C ++R+R C P+ QHGG PC G A E +
Sbjct: 4577 NCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCN 4636
Query: 3459 QREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRA--CSRPPTPEGGRPCPGNHTQS 3516
R CPV GAW W PW C G+ ++RA C+ PP GG C G TQ
Sbjct: 4637 IR-------PCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQM 4689
Query: 3517 RPCQEN--------------STQCTDCGGG--QSLHPCGQPCPRSCQDLSPGSVCQPGSV 3560
+ C E S CGGG Q C P P+ GS Q
Sbjct: 4690 QVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFC 4749
Query: 3561 GCQP--------------TCG--CPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSA 3604
P TC C GQ+ + C P P N R+
Sbjct: 4750 NSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPP-------------PSNGGRAC 4796
Query: 3605 GSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGG 3664
G S +Q CP G W SW W CS SCGGG
Sbjct: 4797 GGPDSQ-----------------------IQRCNTDMCPVDGSWGSWHSWSQCSASCGGG 4833
Query: 3665 EQLRSRRCARP-------PCPGPARQSRTCSTQVC 3692
E+ R R C P PCPG Q C+ Q C
Sbjct: 4834 EKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQAC 4868
Score = 146 bits (369), Expect = 5e-34
Identities = 120/430 (27%), Positives = 149/430 (34%), Gaps = 88/430 (20%)
Query: 2824 PPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAP--GDTTCPGPHSQTRDCNTQP 2881
P + V + W+ W CS C GIQ R R C+ P G C G + R+C +P
Sbjct: 4523 PVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKP 4582
Query: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLP 2941
C G L + ECT C G N +
Sbjct: 4583 CPVD-----------------GSWSEWSLWE----ECTRSCGRG----------NQTRTR 4611
Query: 2942 RSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSC 3001
P HG G + CN CPV WS W W CS SC
Sbjct: 4612 TCNNPSVQHGGRPCEGNAVEIIMCN------------IRPCPVHGAWSAWQPWGTCSESC 4659
Query: 3002 NVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCP--GPGGEWGPWSPCSVPCGGG 3059
G + R R PP AFGG+ C G + + C+ R CP G W WS CSV CGGG
Sbjct: 4660 GKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGG 4719
Query: 3060 YRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTC 3119
R RTRG S + ++ G + C G D Q C P +P TC
Sbjct: 4720 ARQRTRGCSDPVPQY---GGRKCEG-------SDVQSDFCNSDPCPTHGNWSPWSGWGTC 4769
Query: 3120 HPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179
C+ G + C PP S R C I C++ C
Sbjct: 4770 SRTCN--GGQMRRYRTCD-------------NPPPSNGGRACGG---PDSQIQRCNTDMC 4811
Query: 3180 AEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEA 3239
+ +W W WSQCSASCG R R C P+P C G
Sbjct: 4812 PV-DGSWGSWHSWSQCSASCGGGEKTRKRLCDH------------PVPVKGGRPCPGDTT 4858
Query: 3240 EEEPCLLQGC 3249
+ C +Q C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 141 bits (355), Expect = 2e-32
Identities = 119/442 (26%), Positives = 157/442 (35%), Gaps = 127/442 (28%)
Query: 4003 VPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGC 4062
V GG+S+WS W C +CG G RSR C+ P+P G
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQ---------------------PLPANGGK 4566
Query: 4063 PAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR---CPKGSLEQDGGCVPIGHCDC 4119
P CQ + + C+ CP + +C
Sbjct: 4567 P------------------------CQGSDLEMRNCQNKPCPVDGSWSEWSLWE----EC 4598
Query: 4120 TDAQGHSWAPGSQHQD-ACNNCSCQAGQ----------LSCTAQPCPPPTHCAWSHWSAW 4168
T + G G+Q + CNN S Q G + C +PCP H AWS W W
Sbjct: 4599 TRSCGR----GNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCP--VHGAWSAWQPW 4652
Query: 4169 SPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSW 4228
CS SCG +G Q+R R C P PP G S+
Sbjct: 4653 GTCSESCG-KGTQTRARL-------------------CNNP--PP---------AFGGSY 4681
Query: 4229 LQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHR 4288
G + +C + C + W W+SWS C VSCGGG + RTR C P +
Sbjct: 4682 CDG------AETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYG 4735
Query: 4289 SPPCLGPDTQT---RQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSC----PCLMAKA 4341
C G D Q+ PCP W WG CSR+C G R +C P +A
Sbjct: 4736 GRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRA 4795
Query: 4342 DPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSCRVLVQQRYR-----HQGPASRG 4396
+S Q C + CP + W SW SW++CS ++ R H P
Sbjct: 4796 CGGPDS-----QIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVP---- 4846
Query: 4397 ARAGAPCTRLDGHFRPCLISNC 4418
+ G PC C + C
Sbjct: 4847 VKGGRPCPGDTTQVTRCNVQAC 4868
Score = 132 bits (331), Expect = 1e-29
Identities = 123/476 (25%), Positives = 157/476 (32%), Gaps = 150/476 (31%)
Query: 3471 VDGAWGPWGPWSPCDMCLGQS--HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTD 3528
V G + W W C + G+ RSR C++P GG+PC G+ + R CQ
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNK------ 4581
Query: 3529 CGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQ 3588
PC P S + S C T C G ++ C
Sbjct: 4582 --------PC--PVDGSWSEWSLWEEC---------TRSCGRGNQTRTRTC--------- 4613
Query: 3589 YQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVW 3648
N S G R PC+ I+ C P CP G W
Sbjct: 4614 ---------NNPSVQHGGR---------------PCEGNA--VEIIMCNIRP-CPVHGAW 4646
Query: 3649 SSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTC-----STQVCREAGCPAGRLY 3703
S+W PW CS SCG G Q R+R C PP PA C QVC E CP +
Sbjct: 4647 SAWQPWGTCSESCGKGTQTRARLCNNPP---PAFGGSYCDGAETQMQVCNERNCPIHGKW 4703
Query: 3704 RECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQEL 3763
C SC +Q + GC
Sbjct: 4704 ATWASWSACSVSCGGGARQ---RTRGC--------------------------------- 4727
Query: 3764 GATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFGPWSPWGPC 3823
DP G G + + C + C G + PWS WG C
Sbjct: 4728 ----SDPVPQYG-GRKCEGSDVQSDFCNSDPC-------------PTHGNWSPWSGWGTC 4769
Query: 3824 SRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLE-CPSPDCPGAEGSTVEPVTGLPGG 3882
SR+C G G R R C P+ G+ C GP ++ C + CP + G
Sbjct: 4770 SRTCNG-GQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP------------VDGS 4816
Query: 3883 WGPWSSWSPCSRSCTDPARPAWRSRTRLCLANCTM-------GDPLQERPCNLPSC 3931
WG W SWS CS SC ++R RLC + GD Q CN+ +C
Sbjct: 4817 WGSWHSWSQCSASCGG----GEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQAC 4868
Score = 131 bits (330), Expect = 2e-29
Identities = 106/379 (27%), Positives = 141/379 (37%), Gaps = 70/379 (18%)
Query: 3407 VPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY 3466
V GG+ WS W CS C + RSR C P P +GG PC G+ + C +
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPC------QGSDLEMRNCQN- 4580
Query: 3467 ATCPVDGAWGPWGPWSPCDMCLGQSH--RSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
CPVDG+W W W C G+ + R+R C+ P GGRPC GN + C N
Sbjct: 4581 KPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMC--NIR 4638
Query: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLC-VPPA 3583
C G + P G C +CG G ++ LC PP
Sbjct: 4639 PCPVHGAWSAWQPWGT---------------------CSESCG--KGTQTRARLCNNPPP 4675
Query: 3584 HCRCQYQPGA---MGIPENQSRSAGSRFSSWESLEPGEVVTG--------PCDNCTCVAG 3632
Y GA M + ++ ++++W S V G C + G
Sbjct: 4676 AFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYG 4735
Query: 3633 ILQCQ---------EVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPP------- 3676
+C+ CP G WS W W CS +C GG+ R R C PP
Sbjct: 4736 GRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRA 4795
Query: 3677 CPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSC--AHVTQQVGC-FSEGCEEG 3733
C GP Q + C+T + CP + C SC T++ C + G
Sbjct: 4796 CGGPDSQIQRCNTDM-----CPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGG 4850
Query: 3734 CHCPEGTFQHRLACVQECP 3752
CP T Q VQ CP
Sbjct: 4851 RPCPGDTTQVTRCNVQACP 4869
Score = 124 bits (312), Expect = 2e-27
Identities = 94/300 (31%), Positives = 125/300 (41%), Gaps = 48/300 (16%)
Query: 1695 GAWGPWSPWGPCSRTCGPWGQGRSRRCS-PLGLLVLQNCPGPEHQSQACFTAACPVDGEW 1753
G + WS W CS TCG Q RSR C+ PL + C G + + + C CPVDG W
Sbjct: 4530 GGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSW 4589
Query: 1754 STWSPWSVCSEPC-RGTMTRQRQCHSP--QNGGRTCAALPGGLHSTRQTKPCPQDGCPNA 1810
S WS W C+ C RG TR R C++P Q+GGR C + +PCP G +A
Sbjct: 4590 SEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMC-NIRPCPVHGAWSA 4648
Query: 1811 TCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSP-----GCWC----PEGQVLGSEG- 1860
+QP C +C G+ T C +P G +C + QV
Sbjct: 4649 -------WQPWGTCSESC----GKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNC 4697
Query: 1861 -----WCVWPRQCPCLVD---GARYWPGQRIKA--------DCQLCICQDGRPRRCRLNP 1904
W W C V GAR QR + + C D + C +P
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGAR----QRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDP 4753
Query: 1905 DCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPC 1964
C WS WS W C C ++ +R+ +NP PS GR C G + +RC T+ C
Sbjct: 4754 -CPTHGNWSPWSGWGTCSRTCNGGQMR-RYRTCDNPPPSNGGRACGGPDSQIQRCNTDMC 4811
Score = 119 bits (297), Expect = 1e-25
Identities = 86/281 (30%), Positives = 106/281 (37%), Gaps = 63/281 (22%)
Query: 1695 GAWGPWSPWGPCSRTCGPWGQGRSRRCS-PLGLLVLQNCPGPEHQSQACFTAACPVDGEW 1753
GAW W PWG CS +CG Q R+R C+ P C G E Q Q C CP+ G+W
Sbjct: 4644 GAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKW 4703
Query: 1754 STWSPWSVCSEPCRG-TMTRQRQCHSP--QNGGRTCAALPGGLHSTRQTKPCPQDGCPNA 1810
+TW+ WS CS C G R R C P Q GGR C S Q+ C D CP
Sbjct: 4704 ATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEG------SDVQSDFCNSDPCP-- 4755
Query: 1811 TCSGELMFQPCAPCPLTCDDISGQV----TCPPDWPC-GSPGCWCPEGQVLGSEGWCVWP 1865
T + C TC+ GQ+ TC P G C P+ Q+
Sbjct: 4756 THGNWSPWSGWGTCSRTCN--GGQMRRYRTCDNPPPSNGGRACGGPDSQI---------- 4803
Query: 1866 RQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPC 1925
QR D C VD W SW W++C C
Sbjct: 4804 ---------------QRCNTDM------------------CPVDGSWGSWHSWSQCSASC 4830
Query: 1926 GSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEG 1966
G + R ++P P GR C G + RC + C G
Sbjct: 4831 GGGE-KTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPG 4870
Score = 106 bits (265), Expect = 5e-22
Identities = 69/225 (30%), Positives = 93/225 (41%), Gaps = 41/225 (18%)
Query: 2410 CDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMMPTMALPGLPASRALCSPSQL 2469
CDG E + +ER+C + WA AS + CS +
Sbjct: 4682 CDGAETQMQVCNERNCP---------IHGKWATW---------------ASWSACS---V 4714
Query: 2470 SCGSGECLSAE-----------RRCDLRPDCQDGSDEDGC-VDCVLAPWSVWSSCSRSCG 2517
SCG G R+C+ D + D C +PWS W +CSR+C
Sbjct: 4715 SCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCN 4774
Query: 2518 LGLTFQRQELLRPPLPGG--SCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGH 2575
G + + PP G +C + Q C CPV G+W W +W CS SCGGG
Sbjct: 4775 GGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGE 4834
Query: 2576 QSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRV 2620
++R+R C P P GG PCPG + + C +Q C GG G V
Sbjct: 4835 KTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSV 4879
Score = 94.7 bits (234), Expect = 2e-18
Identities = 101/379 (26%), Positives = 130/379 (34%), Gaps = 71/379 (18%)
Query: 4313 WGPWGPCSRSCGPGLASRSGSC-PCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSW 4371
W W CS +CG G+ RS C L A C + L+ + C + PCP + WS W
Sbjct: 4535 WSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGS--DLEMRNCQNKPCPVDGSWSEW 4592
Query: 4372 SSWTRC--SCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFE- 4428
S W C SC Q R R S G PC C I C ++
Sbjct: 4593 SLWEECTRSCGRGNQTRTRTCNNPS-VQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQP 4651
Query: 4429 FHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNC-----WHT 4483
+ C C T +LC + PP G YC G Q C E NC W T
Sbjct: 4652 WGTCSESCGK--GTQTRARLCNNPPPAFGGSYC-DGAETQMQVC---NERNCPIHGKWAT 4705
Query: 4484 SAAGAGMTLAPGD---RLQLGCKECECRRGELHCTSQGCQGLLPLSE-------WSEWSP 4533
A+ + +++ G + GC + + G C Q S+ WS WS
Sbjct: 4706 WASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSG 4765
Query: 4534 CGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAP 4593
G C SRT + R+R C +P P +
Sbjct: 4766 WGTC---------SRTC-------------------NGGQMRRYRTCDNP----PPSNGG 4793
Query: 4594 HLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREP 4653
C P SQ + C + CP W W WS C C GG + R R C P
Sbjct: 4794 RACGGPDSQIQRC-NTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRL--------CDHP 4844
Query: 4654 WAQESCNGGPCPECEAQDT 4672
+ G PCP Q T
Sbjct: 4845 VPVK--GGRPCPGDTTQVT 4861
Score = 94.7 bits (234), Expect = 2e-18
Identities = 81/241 (33%), Positives = 92/241 (38%), Gaps = 48/241 (19%)
Query: 1588 EDCADGSDERG--CGGPCAPHHAPCARGPHCVSPE---QLCDGVRQCPDGSDEGPDA--- 1639
E C G+ R C P P G +C E Q+C+ R CP A
Sbjct: 4657 ESCGKGTQTRARLCNNP-----PPAFGGSYCDGAETQMQVCNE-RNCPIHGKWATWASWS 4710
Query: 1640 -----CGGLPALGGPNRT---GLPCPEYTCPNGTCIGFQLVCDGQPDCGRPGQVGPSPEE 1691
CGG G RT P P+Y C+G P P
Sbjct: 4711 ACSVSCGG----GARQRTRGCSDPVPQYGGRK---------CEGSDVQSDFCNSDPCPTH 4757
Query: 1692 QGCGAWGPWSPWGPCSRTCGPWGQGRSRRC-SPLGLLVLQNCPGPEHQSQACFTAACPVD 1750
G W PWS WG CSRTC R R C +P + C GP+ Q Q C T CPVD
Sbjct: 4758 ---GNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVD 4814
Query: 1751 GEWSTWSPWSVCSEPC-RGTMTRQRQCHS--PQNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
G W +W WS CS C G TR+R C P GGR C PG T Q C C
Sbjct: 4815 GSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPC---PG---DTTQVTRCNVQAC 4868
Query: 1808 P 1808
P
Sbjct: 4869 P 4869
Score = 77.4 bits (189), Expect = 3e-13
Identities = 96/352 (27%), Positives = 115/352 (32%), Gaps = 79/352 (22%)
Query: 4574 QHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSG 4633
Q R RLC P G P C + R C + CP WS W W C C
Sbjct: 4550 QKRSRLCNQPLPANG--GKP--CQGSDLEMRNCQNK-PCPVDGSWSEWSLWEECTRSCGR 4604
Query: 4634 GFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCP-HSCADLWDR 4692
G + R R C P Q G PC E + CP H W
Sbjct: 4605 GNQTRTRT--------CNNPSVQHG--GRPC---EGNAVEIIMCNIRPCPVHGAWSAWQP 4651
Query: 4693 VQCLQGPCRPG-------CRCPP---GQLVQDGRCVPISSCR---CGLPSANASWELAPA 4739
C G C PP G DG + C C + A+W A
Sbjct: 4652 WGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATW--ASW 4709
Query: 4740 QAVQLDC--------QNCT----------CVN---ESLVCPHQECPVLG---PWSAWSSC 4775
A + C + C+ C +S C CP G PWS W +C
Sbjct: 4710 SACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTC 4769
Query: 4776 SAPCGGGTMERHRTCEGGP---GVAPCQAQDTEQRQECNLQPCP---ECPPGQVLSACAT 4829
S C GG M R+RTC+ P G C D+ Q Q CN CP S C+
Sbjct: 4770 SRTCNGGQMRRYRTCDNPPPSNGGRACGGPDS-QIQRCNTDMCPVDGSWGSWHSWSQCSA 4828
Query: 4830 SC-------PCLCWHLQP---GAICVQEPCQ-PGC---GCPGGQLLHNGTCV 4867
SC LC H P G C + Q C CPGG G+ +
Sbjct: 4829 SCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVI 4880
Score = 65.9 bits (159), Expect = 1e-09
Identities = 65/228 (28%), Positives = 84/228 (36%), Gaps = 57/228 (25%)
Query: 4618 WSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLD 4677
+S W W C V C G + R R C +P NGG C+ D +
Sbjct: 4532 FSQWSAWRACSVTCGKGIQKRSRL--------CNQPL---PANGG--KPCQGSDLEMR-N 4577
Query: 4678 CANQ-CP----HSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANA 4732
C N+ CP S LW+ C C GR + C PS
Sbjct: 4578 CQNKPCPVDGSWSEWSLWEE-------CTRSC----------GRGNQTRTRTCNNPSVQH 4620
Query: 4733 SWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSA---WSSCSAPCGGGTMERHRT 4789
AV++ ++C + CPV G WSA W +CS CG GT R R
Sbjct: 4621 GGRPCEGNAVEI-----------IMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARL 4669
Query: 4790 CEGGP---GVAPCQAQDTEQRQECNLQPCP---ECPPGQVLSACATSC 4831
C P G + C +T Q Q CN + CP + SAC+ SC
Sbjct: 4670 CNNPPPAFGGSYCDGAET-QMQVCNERNCPIHGKWATWASWSACSVSC 4716
Score = 35.4 bits (80), Expect = 1.5
Identities = 28/100 (28%), Positives = 34/100 (34%), Gaps = 18/100 (18%)
Query: 3312 TAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPG-----CYCPPGQVLSSNGAICVQPGHCS 3366
T EG+E S C++ C C+ C CPPG L+ NG C C
Sbjct: 5418 TCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDEC- 5476
Query: 3367 CLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
Q H G C + G C D PCP
Sbjct: 5477 -----LEQNVHCGPN-------RMCFNMRGSYQCIDTPCP 5504
Score = 34.3 bits (77), Expect = 3.3
Identities = 59/274 (21%), Positives = 89/274 (32%), Gaps = 42/274 (15%)
Query: 4665 PECEAQDTVFTLDCA--NQCPHSCADLWDRVQCLQGPCRPGCRCPPG-QLVQDGR-CVPI 4720
P C +D +CA N C HSC + C CP G + DGR C I
Sbjct: 5103 PFCADED-----ECAAGNPCSHSCHNAMGTYYC---------SCPKGLTIAADGRTCQDI 5148
Query: 4721 SSCRCGLPSANASWE----LAPAQAVQLDCQNCTCVNESLVCPH-QECPVLGPWSAWSSC 4775
C G + +A + + + V ++ L C EC P C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP------C 5202
Query: 4776 SAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLC 4835
C H CE G + + D + ++ +P C + C CP
Sbjct: 5203 HQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGM 5262
Query: 4836 WHLQPGAICVQEPCQPGC-GCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQEL 4894
+ G + C+ G C Q+ N CP S G + +++
Sbjct: 5263 TKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQV 5322
Query: 4895 PPGTVLTRNCT-RCVCHGGAFSCSLVDCQVPPGE 4927
P + C +C G+F C PPG+
Sbjct: 5323 P------KPCAHQCSNTPGSFKCI-----CPPGQ 5345
Score = 33.9 bits (76), Expect = 4.3
Identities = 43/175 (24%), Positives = 57/175 (32%), Gaps = 29/175 (16%)
Query: 806 RRCAQEGASPPWRNQTLCPVMCPGG--QEYRECAPACGQHCGKPEDCGELGSCVAGCN-- 861
R C G W + + C V C GG Q R C+ Q+ G+ + ++ S CN
Sbjct: 4695 RNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDF--CNSD 4752
Query: 862 -CPLGLLWDP------------EGQCVPPSLC---PCQLGARRYAPGSATMKECNRCICQ 905
CP W P GQ C P G R + ++ CN +C
Sbjct: 4753 PCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Query: 906 ERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSP---SANHSCPAGSTDGCVC 957
G W + H SQ C CD P CP +T C
Sbjct: 4813 VDGSWG--SWHSWSQ--CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRC 4863
Score = 33.9 bits (76), Expect = 4.3
Identities = 63/267 (23%), Positives = 86/267 (32%), Gaps = 63/267 (23%)
Query: 4027 RSRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGI 4086
RS C S + + P + + NP C C M C+ CP+ + +G
Sbjct: 5088 RSNQCPSGFTLDSVGPFCADEDECAAGNP--CSHSCHNAMGTYYCS--CPKGLTIAADGR 5143
Query: 4087 VCQDDQVCQKG--------------------CRCPKGSLEQDGG--CVPIGHCDCTDA-- 4122
CQD C G RC G G C I C +
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCH 5203
Query: 4123 QGHSWAPGSQHQDACNNCSCQAG-QL---------SCTAQPCPPPTHCAWSHWSAWSPCS 4172
Q A GS H C C+ G QL C C P HC + C
Sbjct: 5204 QRCFNAIGSFH------CGCEPGYQLKGRKCMDVNECRQNVCRPDQHC--KNTRGGYKCI 5255
Query: 4173 HSCGPRGQQSRFRSSTSGSWAPECREEQSQ---SQPC--PQPSCPPLCLQGTRSRTLGDS 4227
C P G + EC++ Q +Q C + S +C +G RS+ +G
Sbjct: 5256 DLC-PNGMTKAENGTCID--IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRP 5312
Query: 4228 WLQ-GECQ--------RCSCTPEGVIC 4245
+ EC+ +CS TP C
Sbjct: 5313 CMDINECEQVPKPCAHQCSNTPGSFKC 5339
Score = 33.9 bits (76), Expect = 4.3
Identities = 37/158 (23%), Positives = 54/158 (34%), Gaps = 23/158 (14%)
Query: 2800 RSRLCPSPG--DSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSC 2857
RS CPS DS P A ++E + C + + CS P I GR+C
Sbjct: 5088 RSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYY--CSCPKGLTIAADGRTC 5145
Query: 2858 SSL---APGDTTCPGPHSQTRDCNTQPCTAQC-------PENMLFRSAEQCHQEGGPCPR 2907
+ A G TC + C +C + + + +C QE PC +
Sbjct: 5146 QDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC-QESSPCHQ 5204
Query: 2908 LCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQC 2945
C C C PG L C+ ++C
Sbjct: 5205 RCFNAIGSFHCG--------CEPGYQLKGRKCMDVNEC 5234
Score = 33.9 bits (76), Expect = 4.3
Identities = 53/231 (22%), Positives = 73/231 (31%), Gaps = 29/231 (12%)
Query: 1272 SLQCEGGQVYEACGPTCPPTCHEQHPEPGWH-CQVVACVEGCFCPEGTLL--HGGACLEP 1328
S QC G ++ GP C P H C C CP+G + G C +
Sbjct: 5089 SNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 1329 ASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGG------DGGHCEELVPACAEGEAL 1382
C GR++ G G+ C CG DG C+++
Sbjct: 5149 DECAL--GRHTCHAGQDCDNTIGSYRCVV---RCGSGFRRTSDGLSCQDINE-------- 5195
Query: 1383 CQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCG 1442
CQE+ C C N GS GC +G+ C D+
Sbjct: 5196 CQESSPCHQR---CFN----AIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNT 5248
Query: 1443 DGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCV 1493
G + CP G+ +G C+ DG C E+ G CV
Sbjct: 5249 RGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCV 5299
>gi|157384998 low density lipoprotein receptor-related protein 4 [Homo
sapiens]
Length = 1905
Score = 208 bits (530), Expect = 1e-52
Identities = 132/393 (33%), Positives = 165/393 (41%), Gaps = 69/393 (17%)
Query: 1317 GTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGD---GGHCEE-- 1371
G LL C C GR+ F + G CTC QW C GD G H +E
Sbjct: 11 GALLCAHGLASSPECAC--GRSHF---TCAVSALGECTCIPAQWQCDGDNDCGDHSDEDG 65
Query: 1372 -LVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSSGHCLP 1430
++P C+ + C +NG C+ W+CD +DC D SDE+ C C E + C +G+C+
Sbjct: 66 CILPTCSPLDFHC-DNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIR 124
Query: 1431 LALLCDRQDDCGDGTDE--PSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLG 1488
CD +DCGD +DE C C+DG C+ CDG DC D +DEE+C
Sbjct: 125 SLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPS 184
Query: 1489 QVTCVP---GEVSCVDGTCLGAIQLCDGVWDCPDGADEGPGHCPLPSLPTPPASTLPGPS 1545
V P E C G C+ I CDG DC D +DE
Sbjct: 185 AVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDE---------------------- 222
Query: 1546 PGSLDTASSPLASASPAPPCGPFEFRCGSGECTPRGWRCDQEEDCADGSDERGC-GGPCA 1604
+ S PC EF C SG C GWRCD + DC D SDER C C
Sbjct: 223 -----------SDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCT 271
Query: 1605 PHHAPCARGPHCVSPEQLCDGVRQCPDGSDEGPDACGGLPALGGPNRTGLP---CPEYTC 1661
C G CV CDG C D SDE + C TG P ++ C
Sbjct: 272 AEQFRCHSG-RCVRLSWRCDGEDDCADNSDE--ENC---------ENTGSPQCALDQFLC 319
Query: 1662 PNGTCIGFQLVCDGQPDCGRPGQVGPSPEEQGC 1694
NG CIG + +C+G DCG P +Q C
Sbjct: 320 WNGRCIGQRKLCNGVNDCGDNSDESP---QQNC 349
Score = 63.2 bits (152), Expect = 7e-09
Identities = 71/297 (23%), Positives = 94/297 (31%), Gaps = 104/297 (35%)
Query: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
Y C+ D CD DC ++DE + H RS E C+ G A
Sbjct: 200 YGRCILDIYHCDGDDDC-------GDWSDE-SDCSSHQPCRSGE---FMCDSGLCINA-- 246
Query: 1286 PTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSV 1345
GW C G A + S
Sbjct: 247 --------------GWRCD-----------------GDADCDDQSD-------------- 261
Query: 1346 LQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDG 1405
+++C C Q+ C +G CV W CD +DDC D
Sbjct: 262 -ERNCTTSMCTAEQFRC----------------------HSGRCVRLSWRCDGEDDCADN 298
Query: 1406 SDEEGC---AAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADG 1462
SDEE C +P C Q C +G C+ LC+ +DCGD +DE PQ
Sbjct: 299 SDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDE----SPQ-------Q 347
Query: 1463 RCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVSCVDGTCLGAIQLCDGVWDCPD 1519
C P G +C + C + V G V C TC +L + C D
Sbjct: 348 NCRPRT----GEENC--NVNNGGCAQKCQMVRGAVQC---TCHTGYRLTEDGHTCQD 395
Score = 59.3 bits (142), Expect = 1e-07
Identities = 34/119 (28%), Positives = 44/119 (36%), Gaps = 35/119 (29%)
Query: 2387 PPVQCGPGQTPCEVLGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVP 2446
PP +C + PC+ C+ CDG DC D SDE+ R
Sbjct: 106 PPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRK------------------ 147
Query: 2447 FMMPTMALPGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVDCVLAP 2505
CS + C G C++ CD DC+DGSDE+ C V AP
Sbjct: 148 -----------------CSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAP 189
Score = 57.4 bits (137), Expect = 4e-07
Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 39/125 (31%)
Query: 2391 CGPGQTPCEVLGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMMP 2450
C G+ C+ C+ CDG DC D SDER+C
Sbjct: 231 CRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNC------------------------- 265
Query: 2451 TMALPGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGCVD-----CVLAP 2505
+ ++C+ Q C SG C+ RCD DC D SDE+ C + C L
Sbjct: 266 ---------TTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQ 316
Query: 2506 WSVWS 2510
+ W+
Sbjct: 317 FLCWN 321
Score = 50.4 bits (119), Expect = 4e-05
Identities = 32/109 (29%), Positives = 41/109 (37%), Gaps = 30/109 (27%)
Query: 2390 QCGPGQTPCEVLGCVEQAQVCDGREDCLDGSDERHCARNLLMWLPSLPALWAASTVPFMM 2449
+C + C C+ + CDG DC DGSDE +C PS
Sbjct: 147 KCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENC--------PS-------------- 184
Query: 2450 PTMALPGLPASRALCSPSQLSCGSGECLSAERRCDLRPDCQDGSDEDGC 2498
A+P P C+ + C G C+ CD DC D SDE C
Sbjct: 185 ---AVPAPP-----CNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDC 225
Score = 47.0 bits (110), Expect = 5e-04
Identities = 110/515 (21%), Positives = 153/515 (29%), Gaps = 124/515 (24%)
Query: 2440 WAASTVPFMMPTMALPGLPASRALCSPSQLSC-----GSGECLSAERRCDLRPDCQDGSD 2494
W A + ++ L P C S +C G C+ A+ +CD DC D SD
Sbjct: 5 WGALLLGALLCAHGLASSP--ECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSD 62
Query: 2495 EDGCVDCVLAPWSVW---SSCSRSCGL--GLTFQRQELLRPPLPGGSCPRDRFRSQSCFV 2549
EDGC+ +P C R + G + P C D F Q+ +
Sbjct: 63 EDGCILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYC 122
Query: 2550 QACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPC 2609
++W G Q R C D + C C
Sbjct: 123 -------IRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWY--------C 167
Query: 2610 SGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRC 2669
G TDC+ G + C + P PP L+ C G RC +L C
Sbjct: 168 DGDTDCKDGS---DEENCPSAV--PAPPCNLE-------EFQCAYG-RC----ILDIYHC 210
Query: 2670 LPLSECPCLVGEELKWPGVSFLLGNC-SQCVCEKGELLCQPGGCPLPCGWSAWSSWAPCD 2728
+C W S +C S C GE +C G C + GW CD
Sbjct: 211 DGDDDCG-------DWSDES----DCSSHQPCRSGEFMCDSGLC-INAGWR-------CD 251
Query: 2729 RSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVFGWTPWTSWSSCSQSC 2788
G A C+ E ++C E F S C
Sbjct: 252 ---------------------GDADCDDQSDERNCTTSMCTAEQF--------RCHSGRC 282
Query: 2789 LAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPCDG 2848
+ WR C D + D E P C + W
Sbjct: 283 VR----LSWR-----CDGEDDCADNSDEENCENTGSPQCALDQFL-CWNGRCIGQRKLCN 332
Query: 2849 GIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC--------HQ 2900
G+ G + S +P P + + N C +C + R A QC +
Sbjct: 333 GVNDCGDN-SDESPQQNCRPRTGEENCNVNNGGCAQKC---QMVRGAVQCTCHTGYRLTE 388
Query: 2901 EGGPCPRLCLTQGPGIECT--GFCAPGCTCPPGLF 2933
+G C + EC G+C+ GCT G F
Sbjct: 389 DGHTCQDV-------NECAEEGYCSQGCTNSEGAF 416
Score = 44.3 bits (103), Expect = 0.003
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 2232 PLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGC 2268
P C + C +G+C+ R CDG DCED SDE+ C
Sbjct: 69 PTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDC 105
Score = 43.9 bits (102), Expect = 0.004
Identities = 17/35 (48%), Positives = 20/35 (57%)
Query: 2234 CPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGC 2268
C RC+ G C+ CDG DC+DGSDEE C
Sbjct: 148 CSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENC 182
Score = 42.4 bits (98), Expect = 0.012
Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 2233 LCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGCVLLPEGTG 2276
+C RC SG CV CDG DC D SDEE C E TG
Sbjct: 269 MCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENC----ENTG 308
Score = 42.0 bits (97), Expect = 0.016
Identities = 20/43 (46%), Positives = 23/43 (53%)
Query: 2226 PGSPPAPLCPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGC 2268
P + PAP C +CA G C+L CDG DC D SDE C
Sbjct: 183 PSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDC 225
Score = 38.1 bits (87), Expect = 0.23
Identities = 90/438 (20%), Positives = 127/438 (28%), Gaps = 127/438 (28%)
Query: 4114 IGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPP-PTHCAWSHWSAWSPCS 4172
+G C C AQ D N+C + + C C P HC +
Sbjct: 39 LGECTCIPAQWQC--------DGDNDCGDHSDEDGCILPTCSPLDFHCD----------N 80
Query: 4173 HSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPP---LCLQGTRSRTL----- 4224
C R S +C E+ S Q CP C C G R+L
Sbjct: 81 GKC--------IRRSWVCDGDNDC-EDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCDG 131
Query: 4225 ----GDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRAC 4280
GD+ +C C+ + C D C + E W + D C G+ C
Sbjct: 132 DNDCGDN-SDEQCDMRKCSDKEFRCSDGSC-IAEHW-----YCDGDTDCKDGSDEEN--C 182
Query: 4281 RAAAPHHRSPPCLGPDTQTRQ-------QPCPGLLEACSWGPWGPCSRS---------CG 4324
+A P +PPC + Q C G + W CS C
Sbjct: 183 PSAVP---APPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCD 239
Query: 4325 PGLASRSG-----SCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTRCSC 4379
GL +G C + C ++ + C+SG CV SW C
Sbjct: 240 SGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSG----RCVRLSWRCDGEDDC 295
Query: 4380 RVLVQQRYRHQGPASRGARAGAPCTRLD----------GHFRPCL-ISNCSEDSCTPPFE 4428
G+P LD G + C +++C ++S P +
Sbjct: 296 A--------DNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQ 347
Query: 4429 F--------------HACGSPC-----AGLCATHLSHQL------CQDLPPCQPGCYCPK 4463
C C A C H ++L CQD+ C YC +
Sbjct: 348 NCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQ 407
Query: 4464 GLLEQAGGCIPPEECNCW 4481
G G CW
Sbjct: 408 GCTNSEGA------FQCW 419
Score = 38.1 bits (87), Expect = 0.23
Identities = 16/35 (45%), Positives = 18/35 (51%)
Query: 2234 CPGVGLRCASGECVLRGGPCDGVLDCEDGSDEEGC 2268
C C SG C+ G CDG DC+D SDE C
Sbjct: 231 CRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNC 265
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 199 bits (507), Expect = 5e-50
Identities = 142/516 (27%), Positives = 223/516 (43%), Gaps = 45/516 (8%)
Query: 413 EYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRH--IHIRWRKPG--FCE-R 467
+Y C+ YC Q + + C T++ + CA WR CE +
Sbjct: 687 DYKMICIDEYC--------QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQ 738
Query: 468 LCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGT----LCVPAAH 523
CP +Y +C P +C V ++ ECVSGC CP G + CV A
Sbjct: 739 RCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEGYLLDDIGEKGKCVLKAE 794
Query: 524 CPCYYCRQRYVPGDTVRQLC-NPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSF 582
CPC Y PG+ C + C C+D +W C +ALCP C V G TFDG Y+F
Sbjct: 795 CPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNF 853
Query: 583 WGGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDT---HIQLRDSGAVLVN 639
G C + V + + L + G+CL+++++ L + + +S + N
Sbjct: 854 PGN--CHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTN 911
Query: 640 GQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVA--YITLDPRHAHQVQGLC 697
+ + ++ + + ASS++L + L PV Y+++ P GLC
Sbjct: 912 DKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLC 971
Query: 698 GTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEA 757
G++ +DDF++ +E + AFA+ +++ CP + S C + ++ FAE
Sbjct: 972 GSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNP---SSCIS-IEKEKFAER 1024
Query: 758 ACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQ-EGAS 814
C IL S CH +V+ +P++ C C C+ DCLC +L Y + CA+ E
Sbjct: 1025 HCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYI 1084
Query: 815 PPWRNQTLCPVMCPGGQEYRECAPACGQHC----GKPEDCGELGSCVAGCNCPLGLLWDP 870
WR LC CP G ++ AC C + C V GC CP + +
Sbjct: 1085 VGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNN 1143
Query: 871 EGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQE 906
EG CV S C C + PG + N+C+C++
Sbjct: 1144 EGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRD 1179
Score = 172 bits (435), Expect = 1e-41
Identities = 128/467 (27%), Positives = 197/467 (42%), Gaps = 33/467 (7%)
Query: 912 CTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD----ER 967
C + CP Q P C +P + C GC CP G +L D +
Sbjct: 735 CETQRCPEQHIYKECGPSNPATCSNV--APFQDSEC----VSGCTCPEGYLLDDIGEKGK 788
Query: 968 CVPPDLCPCRHSGQWYLPNATIQEDC-NVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
CV CPC SG Y P + C + C C+ +W CT GRC+ G+ TFD
Sbjct: 789 CVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFD 847
Query: 1027 GLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVV---HMLRGR 1083
G+ + +PG C +L V +V + P G +G TC ++ + L +V ++
Sbjct: 848 GVKYNFPGNCHFLAVHNEDWSISVELRPCPSGQTG-TCLNSVTLLLNSSVPVDKYVFNSD 906
Query: 1084 AVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST--HLGLTLLWDGGTRVLVQLSPQFRGR 1141
N Y+ + +L + T H+ L + ++ V + P
Sbjct: 907 GTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTD 966
Query: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWA 1201
GLCG ++ A +D S Q +LE T++ A+SW + CP+ P C ++ + +A
Sbjct: 967 TVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPKGN--PSSC-ISIEKEKFA 1022
Query: 1202 RARCGALLQ---PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECA- 1257
CG LL PL + CH V P+ ++E C C C++ D CLC+ + Y CA
Sbjct: 1023 ERHCGILLDSSGPLAS-CHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAE 1079
Query: 1258 RHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVV-ACVEGCFCPE 1316
+ + V WR+ LC C G V++ C +C E C V V+GC CP+
Sbjct: 1080 KETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSL-SERDRSCDVEDVPVDGCTCPD 1137
Query: 1317 GTLLHG-GACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
+ G C+ + C C PG ++ D C C++G C
Sbjct: 1138 AMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLC 1184
Score = 137 bits (344), Expect = 4e-31
Identities = 120/459 (26%), Positives = 178/459 (38%), Gaps = 81/459 (17%)
Query: 923 CPRELV--YAPGACLLTCDSPSA-NHSCPAGST--DGCVCPPGTVLLDE-RCVPPDLCPC 976
CP LV Y AC +C S S + SC DGC CP +E CV C C
Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 1155
Query: 977 RHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGAC 1036
+ + P I D N CVCR DG+ C
Sbjct: 1156 YINDEVMQPGKLIHTDDNKCVCR--------------------------DGILL-----C 1184
Query: 1037 EYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPK 1096
+ + ++ QN GA + C+ A R R + + V
Sbjct: 1185 QIPI--------DLTLQNCSGGAEYVDCSDPKAQRRTN--------RTCSTRNIPVFDD- 1227
Query: 1097 VYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASND 1156
Y G G F +L+ + + G ++ F+G+V GLCG+ +GD +D
Sbjct: 1228 -YCG-----HENGTFRILTESVPCC---EDGLTCSRKIIVAFQGKVCGLCGNNNGDLKDD 1278
Query: 1157 LRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLC 1216
+R + A +SW+ S C + PC N + WA +C L F C
Sbjct: 1279 FTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDC 1338
Query: 1217 HAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
H +V P +++ C+ +AC CD G C+A+A YA+ C+ G V WR LC + C+
Sbjct: 1339 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD 1398
Query: 1277 GGQV-------YEACGPTCPPTCHEQHPEPGWHCQVVACVEGCF--CPEGTLL---HGGA 1324
YE CG TC +Q + + +EGC+ CP+ +
Sbjct: 1399 YYNAPGECRWHYEPCGTVTAKTCKDQLVGQ----KFSSLLEGCYAKCPDSAPYLDENTMK 1454
Query: 1325 CLEPASCPCEWGRNSFPPGSVLQKDCG-NCTCQEGQWHC 1362
C+ + C C + + P G V++ +CG C C GQ C
Sbjct: 1455 CVSLSECSCFY-NDVIPAGGVIEDNCGRTCYCIAGQLEC 1492
Score = 127 bits (319), Expect = 3e-28
Identities = 104/372 (27%), Positives = 150/372 (40%), Gaps = 43/372 (11%)
Query: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCP--QPGHC-QRVTM------ 250
G TFDG Y+F G C +L D + +V L P CP Q G C VT+
Sbjct: 840 GSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVELRP---CPSGQTGTCLNSVTLLLNSSV 896
Query: 251 GPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG--SIS 308
++ + + ++ +G + +L + V +++ +
Sbjct: 897 PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 956
Query: 309 ISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVA 368
+S+ + T GLCG YN EDDFM L + F NSW + G
Sbjct: 957 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-------- 1008
Query: 369 QGCDPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGA 426
+P I + E A+ C LL+ GP CH V+P YHE C C
Sbjct: 1009 ---NPSSCISIEKEKF-----AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC- 1059
Query: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPSC 486
E Q +C +YV+ACA + +I + G CE CP G ++ V C SC
Sbjct: 1060 ------ENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSC 1113
Query: 487 EAVGQGEEESCREE--CVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQLC 543
++ + + SC E V GC CP ++ N CV + C CY + PG +
Sbjct: 1114 RSLSE-RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD 1172
Query: 544 NPCVCRDGRWHC 555
N CVCRDG C
Sbjct: 1173 NKCVCRDGILLC 1184
Score = 99.4 bits (246), Expect = 8e-20
Identities = 74/256 (28%), Positives = 105/256 (41%), Gaps = 38/256 (14%)
Query: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGL 376
G+ GLCG NG +DDF +A A FGNSW+ + C D V CD
Sbjct: 1262 GKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSDTVAQTFPCD---- 1314
Query: 377 IDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQ 436
+ +A A C L + F CH +V P+ YH+ C+ CA M EG+
Sbjct: 1315 -----SNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDM-----EGKY 1364
Query: 437 QAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEES 496
C A Y +AC+ + + WRKP C C Y + C E G ++
Sbjct: 1365 LGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD----YYNAPGECRWHYEPCGTVTAKT 1420
Query: 497 CREECV--------SGC--ECPRG---LFWNGTLCVPAAHCPCYYCRQRYVP-GDTVRQL 542
C+++ V GC +CP L N CV + C C+Y +P G +
Sbjct: 1421 CKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFY--NDVIPAGGVIEDN 1478
Query: 543 C-NPCVCRDGRWHCAQ 557
C C C G+ C++
Sbjct: 1479 CGRTCYCIAGQLECSE 1494
Score = 89.7 bits (221), Expect = 7e-17
Identities = 80/305 (26%), Positives = 116/305 (38%), Gaps = 29/305 (9%)
Query: 692 QVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQR 751
+V GLCG + +DDF T V + F + ++ + + C S+ A PC ++
Sbjct: 1263 KVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE--C-SDTVAQTFPCDSNPYC 1319
Query: 752 HAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCL--CPVLSAYARRCA 809
A+A C IL S F++CH VD ++ C+ C CD L C ++ YA C+
Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379
Query: 810 QEGASPPWRNQTLCPVMC-----PG--GQEYRECAPACGQHCGKPEDCGELGSCVAGC-- 860
G WR LCPV C PG Y C + C + S + GC
Sbjct: 1380 AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYA 1439
Query: 861 NCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKE-CNRCICQERGLWNCTARHCPS 919
CP + E SL C P +++ C R G C+ +
Sbjct: 1440 KCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRTCYCIAGQLECSETAPTN 1499
Query: 920 QAFC----PRELVYAPGACL-LTCDSPSANHSCPA---------GSTDGCVCPPGTVLLD 965
F + + GA + L PS S PA G+T G + P T +
Sbjct: 1500 STFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTTGIT 1559
Query: 966 ERCVP 970
E VP
Sbjct: 1560 ETSVP 1564
Score = 75.5 bits (184), Expect = 1e-12
Identities = 60/205 (29%), Positives = 81/205 (39%), Gaps = 41/205 (20%)
Query: 798 CPVLSAYARRCAQEGASP--PWRNQT--LCPVM-CPGGQEYRECAPACGQHCGKPEDCGE 852
C S +R CA +G WR+ + +C CP Y+EC P+ C +
Sbjct: 706 CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQD 765
Query: 853 LGSCVAGCNCPLGLLWDP---EGQCVPPSLCPCQLGARRYAPGSATMKEC-NRCICQERG 908
CV+GC CP G L D +G+CV + CPC+ Y PG C ++C CQ+
Sbjct: 766 -SECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD-A 823
Query: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSAN---------------------HSC 947
W+CT CP + C E G+ L T D N C
Sbjct: 824 KWSCTEALCPGR--CKVE-----GSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPC 876
Query: 948 PAGSTDGCVCPPGTVLLDERCVPPD 972
P+G T C+ LL VP D
Sbjct: 877 PSGQTGTCL--NSVTLLLNSSVPVD 899
Score = 65.1 bits (157), Expect = 2e-09
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 21/148 (14%)
Query: 2851 QTRGRS--CSSLAPGDTTC----PGPHSQTRDCNTQPC-TAQCPENMLFRSAEQCHQEGG 2903
QTR ++ C + + C PG R + C T +CPE +++ E G
Sbjct: 698 QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYK-------ECG 750
Query: 2904 PC-PRLCLTQGPGIECTGFCAPGCTCPPGLFLHN----ASCLPRSQCPCQLHGQLYASGA 2958
P P C P + C GCTCP G L + C+ +++CPC+ G +Y G
Sbjct: 751 PSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 808
Query: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
+ + CTC K +CT CP C
Sbjct: 809 VREGPCGSQCTCQDAKWSCTEALCPGRC 836
Score = 62.8 bits (151), Expect = 9e-09
Identities = 54/203 (26%), Positives = 78/203 (38%), Gaps = 23/203 (11%)
Query: 1761 VCSEPCRGTMTRQRQCHSPQNGGRTCAAL-PGGLHSTRQTKPCPQDGCPNATCSGELMFQ 1819
+C + T + C + R CA+ PG S R C C + +++
Sbjct: 691 ICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV---CETQRCPEQHIYK 747
Query: 1820 PCAPC-PLTCDDISGQVTCPPDWPCGSPGCWCPEGQVL---GSEGWCVWPRQCPCLVDGA 1875
C P P TC +++ D C S GC CPEG +L G +G CV +CPC G
Sbjct: 748 ECGPSNPATCSNVAPF----QDSECVS-GCTCPEGYLLDDIGEKGKCVLKAECPCESSGT 802
Query: 1876 RYWPGQRIKADC-QLCICQDGR--------PRRCRLNPDCAVDCGWSSWSPWAKCLGPCG 1926
Y PG+ + C C CQD + P RC++ ++ C
Sbjct: 803 VYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNFPGNC-HFLA 861
Query: 1927 SQSIQWSFRSSNNPRPSGRGRQC 1949
+ WS P PSG+ C
Sbjct: 862 VHNEDWSISVELRPCPSGQTGTC 884
Score = 54.7 bits (130), Expect = 2e-06
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 13/110 (11%)
Query: 3300 VCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCV-WRCQPGCYCPPGQVLSSNG-- 3356
VC+ CP E Y CGP P +C ++ C GC CP G +L G
Sbjct: 734 VCETQRCP-------EQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEK 786
Query: 3357 AICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
CV C C +G + PG P G + CTC + + +CT+ CP
Sbjct: 787 GKCVLKAECPCES--SGTVYQPGEVREGPCG-SQCTCQDAKWSCTEALCP 833
Score = 53.9 bits (128), Expect = 4e-06
Identities = 55/195 (28%), Positives = 78/195 (40%), Gaps = 33/195 (16%)
Query: 3620 VTGPCDNCT------CVAGILQCQEVPDCPDPGVW---SSWGPWEDCSVSCGGGEQLRSR 3670
+ G C N C GI +C +V + + D + +C +L SR
Sbjct: 656 IPGDCPNAVGKSYEVCEDGIQKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSEL-SR 714
Query: 3671 RCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEG- 3729
CA PG R+ S VC CP +Y+EC P P +C++V F +
Sbjct: 715 LCASDG-PGTFESWRSDSDVVCETQRCPEQHIYKECGPSN--PATCSNVAP----FQDSE 767
Query: 3730 CEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTS 3789
C GC CPEG + ++ CVL A E T+ PG E+ G
Sbjct: 768 CVSGCTCPEGYLLDDIG--EKGKCVLKAECPCESSGTVYQPG-------EVREG-----P 813
Query: 3790 CGN-CSCAHGKLSCS 3803
CG+ C+C K SC+
Sbjct: 814 CGSQCTCQDAKWSCT 828
Score = 53.5 bits (127), Expect = 5e-06
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 10/99 (10%)
Query: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQD----GGCVPIGHC 4117
CP C P CS+ + D C GC CP+G L D G CV C
Sbjct: 740 CPEQHIYKECGPSNPATCSN----VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAEC 795
Query: 4118 DCTDAQGHSWAPGSQHQDAC-NNCSCQAGQLSCTAQPCP 4155
C ++ G + PG + C + C+CQ + SCT CP
Sbjct: 796 PC-ESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCP 833
Score = 52.4 bits (124), Expect = 1e-05
Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 14/98 (14%)
Query: 3090 CPRDKQWLDCA-QGPASCAELSAPRGTNQTCHPGCHCPSGMLLLN----NVCVPTQDCPC 3144
CP + +C PA+C+ ++ + + C GC CP G LL + CV +CPC
Sbjct: 740 CPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPC 797
Query: 3145 AHEGHLYPPGSTVVRPC-ENCSCVSGLIANCSSWPCAE 3181
G +Y PG PC C+C + W C E
Sbjct: 798 ESSGTVYQPGEVREGPCGSQCTCQD------AKWSCTE 829
Score = 50.4 bits (119), Expect = 4e-05
Identities = 41/143 (28%), Positives = 50/143 (34%), Gaps = 27/143 (18%)
Query: 4785 ERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAI 4843
E R C GPG D++ C Q CPE + C S P C ++ P
Sbjct: 711 ELSRLCASDGPGTFESWRSDSDV--VCETQRCPE---QHIYKECGPSNPATCSNVAPFQ- 764
Query: 4844 CVQEPCQPGCGCPGGQLL----HNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTV 4899
C GC CP G LL G CV CPC E PG V
Sbjct: 765 --DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPC-------------ESSGTVYQPGEV 809
Query: 4900 LTRNC-TRCVCHGGAFSCSLVDC 4921
C ++C C +SC+ C
Sbjct: 810 REGPCGSQCTCQDAKWSCTEALC 832
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/70 (38%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 2652 CVEGCRCPPGLLLHDT----RCLPLSECPCLVGEELKWPGVSFLLGNC-SQCVCEKGELL 2706
CV GC CP G LL D +C+ +ECPC + PG G C SQC C+ +
Sbjct: 768 CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG-EVREGPCGSQCTCQDAKWS 826
Query: 2707 CQPGGCPLPC 2716
C CP C
Sbjct: 827 CTEALCPGRC 836
Score = 48.1 bits (113), Expect = 2e-04
Identities = 25/89 (28%), Positives = 38/89 (42%)
Query: 1807 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPR 1866
C ++ SG + C +C +S + GC CP+ +EG CV
Sbjct: 1092 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 1151
Query: 1867 QCPCLVDGARYWPGQRIKADCQLCICQDG 1895
QC C ++ PG+ I D C+C+DG
Sbjct: 1152 QCDCYINDEVMQPGKLIHTDDNKCVCRDG 1180
Score = 47.0 bits (110), Expect = 5e-04
Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 2627 CQKGLV-----PPCPPSCLD-PKANRSCSGHCV--EGCRCPPGLLLHDT-RCLPLSECPC 2677
C GLV C SC + +RSC V +GC CP + ++ C+ S+C C
Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 1155
Query: 2678 LVGEELKWPGVSFLLGNCSQCVCEKGELLCQ 2708
+ +E+ PG + + ++CVC G LLCQ
Sbjct: 1156 YINDEVMQPG-KLIHTDDNKCVCRDGILLCQ 1185
Score = 46.6 bits (109), Expect = 6e-04
Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 7/123 (5%)
Query: 2857 CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFR-SAEQCHQEGGPCPRLCLTQGPG 2915
C+ L C + T C CP ++F+ + + C+ C L +
Sbjct: 1067 CTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS---CRSLS-ERDRS 1122
Query: 2916 IECTGFCAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGK 2974
+ GCTCP ++ +N +C+ +SQC C ++ ++ G + D N C C G
Sbjct: 1123 CDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD-NKCVCRDGI 1181
Query: 2975 MAC 2977
+ C
Sbjct: 1182 LLC 1184
Score = 46.6 bits (109), Expect = 6e-04
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 3/94 (3%)
Query: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQE-GIVCQDDQVCQKGCRCPKGSLE-QDGGCVPIG 4115
CE CP+G+ C C L E C + V GC CP + +G CV
Sbjct: 1092 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 1151
Query: 4116 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSC 4149
CDC PG N C C+ G L C
Sbjct: 1152 QCDCY-INDEVMQPGKLIHTDDNKCVCRDGILLC 1184
Score = 45.1 bits (105), Expect = 0.002
Identities = 36/137 (26%), Positives = 51/137 (37%), Gaps = 23/137 (16%)
Query: 4639 WREAEALC---GGGCREPWAQES---CNGGPCPECEAQDTVFTLDCANQCPHSCADLWDR 4692
+ E LC G G E W +S C CPE +C P +C+++
Sbjct: 709 YSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYK-----ECGPSNPATCSNV--- 760
Query: 4693 VQCLQGPCRPGCRCPPGQLVQD----GRCVPISSCRCGLPSANASWELAPAQAVQLDC-Q 4747
C GC CP G L+ D G+CV + C C ++ P + + C
Sbjct: 761 APFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPC----ESSGTVYQPGEVREGPCGS 816
Query: 4748 NCTCVNESLVCPHQECP 4764
CTC + C CP
Sbjct: 817 QCTCQDAKWSCTEALCP 833
Score = 43.9 bits (102), Expect = 0.004
Identities = 38/139 (27%), Positives = 47/139 (33%), Gaps = 31/139 (22%)
Query: 3510 PGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCP 3569
PG R + + C CG P +C +++P + C C CP
Sbjct: 721 PGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDSE-----CVSGCTCP 775
Query: 3570 LGQLSQD----GLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPC- 3624
G L D G CV A C C+ SS +PGEV GPC
Sbjct: 776 EGYLLDDIGEKGKCVLKAECPCE--------------------SSGTVYQPGEVREGPCG 815
Query: 3625 DNCTCVAGILQCQEVPDCP 3643
CTC C E CP
Sbjct: 816 SQCTCQDAKWSCTEAL-CP 833
Score = 42.7 bits (99), Expect = 0.009
Identities = 28/109 (25%), Positives = 40/109 (36%), Gaps = 14/109 (12%)
Query: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLL----EQAGGCI 4473
C C + CG C+ Q + C GC CP+G L + G C+
Sbjct: 735 CETQRCPEQHIYKECGPSNPATCSNVAPFQDSE----CVSGCTCPEGYLLDDIGEKGKCV 790
Query: 4474 PPEECNCWHTSAAGAGMTLAPGDRLQLGC-KECECRRGELHCTSQGCQG 4521
EC C +G PG+ + C +C C+ + CT C G
Sbjct: 791 LKAECPC-----ESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPG 834
Score = 41.2 bits (95), Expect = 0.027
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQ-AGGCIPPEECNCWHTSA 4485
+ AC S C L S + +D+P GC CP + + G C+ +C+C+
Sbjct: 1104 YNVKACNSSCRSLSERDRSCDV-EDVPV--DGCTCPDAMYQNNEGNCVLKSQCDCYINDE 1160
Query: 4486 AGAGMTLAPGDRLQLGCKECECRRGELHC------TSQGCQG 4521
+ PG + +C CR G L C T Q C G
Sbjct: 1161 V-----MQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSG 1197
Score = 39.7 bits (91), Expect = 0.078
Identities = 44/179 (24%), Positives = 70/179 (39%), Gaps = 32/179 (17%)
Query: 4818 CPPGQVLSACATSCPCLCWHL--QPGAICVQEPCQPGCGCPGGQLLHN-GTCVPPTACPC 4874
CP G V +C C L + + V++ GC CP +N G CV + C C
Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 1155
Query: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAP 4934
+ + + PG ++ + +CVC G ++ CQ+P T Q +
Sbjct: 1156 YIND-------------EVMQPGKLIHTDDNKCVCRDG-----ILLCQIPIDLTLQNCSG 1197
Query: 4935 GELGLCEQTCLEMNA-TKTQSNCSSARA----SGCVCQPGHFR--SQAGPCVPEDHCEC 4986
G + C + A +T CS+ C + G FR +++ PC ED C
Sbjct: 1198 GAEYV---DCSDPKAQRRTNRTCSTRNIPVFDDYCGHENGTFRILTESVPCC-EDGLTC 1252
Score = 38.9 bits (89), Expect = 0.13
Identities = 16/76 (21%), Positives = 28/76 (36%)
Query: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEW 4999
C +C ++ + GC C +++ G CV + C+C+ PG
Sbjct: 1109 CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLI 1168
Query: 5000 QEACESCLCLSGRPVC 5015
C+C G +C
Sbjct: 1169 HTDDNKCVCRDGILLC 1184
Score = 38.1 bits (87), Expect = 0.23
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 4/67 (5%)
Query: 4962 SGCVCQPGHFRS---QAGPCVPEDHCECWHLGRPHLPGSEWQEACES-CLCLSGRPVCTQ 5017
SGC C G+ + G CV + C C G + PG + C S C C + CT+
Sbjct: 770 SGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTE 829
Query: 5018 HCSPLTC 5024
P C
Sbjct: 830 ALCPGRC 836
Score = 36.6 bits (83), Expect = 0.66
Identities = 54/228 (23%), Positives = 80/228 (35%), Gaps = 57/228 (25%)
Query: 3479 GPWSPCDMCLGQSHRSRACSRPP-TPEGGRPCP----GNHTQSRPCQENSTQCTDCGGGQ 3533
GP + C + C + T E + C GN+ ++ C E T G
Sbjct: 1034 GPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKA--CAEKETYIVGWRTGL 1091
Query: 3534 SLHPCG---------QPCPRSCQDLSPGS-VCQPGSVGCQPTCGCPLGQL-SQDGLCVPP 3582
H C + C SC+ LS C V C CP + +G CV
Sbjct: 1092 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-CTCPDAMYQNNEGNCVLK 1150
Query: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDC 3642
+ C C + + E ++PG+++ + C C GIL CQ D
Sbjct: 1151 SQCDC--------------------YINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDL 1190
Query: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQ 3690
++CS GG E + C+ P R +RTCST+
Sbjct: 1191 ----------TLQNCS---GGAEYV---DCSDP--KAQRRTNRTCSTR 1220
Score = 35.0 bits (79), Expect = 1.9
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 9/76 (11%)
Query: 2638 SCLDPKANRSCSGHCVEGC--RCP---PGLLLHDTRCLPLSECPCLVGEELKWPGVSFLL 2692
+C D + S +EGC +CP P L + +C+ LSEC C + + GV +
Sbjct: 1420 TCKDQLVGQKFSS-LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGV--IE 1476
Query: 2693 GNCSQ-CVCEKGELLC 2707
NC + C C G+L C
Sbjct: 1477 DNCGRTCYCIAGQLEC 1492
Score = 34.3 bits (77), Expect = 3.3
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 13/91 (14%)
Query: 3319 YSPCGPPCPRSCDDLV--HCVWRCQPGCY--CP-PGQVLSSNGAICVQPGHCSCL--DLL 3371
Y PCG ++C D + GCY CP L N CV CSC D++
Sbjct: 1410 YEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI 1469
Query: 3372 TGQRHHPGARLARPDGCNHCTCLEGRLNCTD 3402
P + + C C+ G+L C++
Sbjct: 1470 ------PAGGVIEDNCGRTCYCIAGQLECSE 1494
Score = 34.3 bits (77), Expect = 3.3
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 23/104 (22%)
Query: 3537 PCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGL-CVPPAHCRCQYQPGAMG 3595
PCG ++C+D G GC C L ++ + CV + C C Y
Sbjct: 1412 PCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYN----- 1466
Query: 3596 IPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTCVAGILQCQE 3638
+ + G V+ C C C+AG L+C E
Sbjct: 1467 ----------------DVIPAGGVIEDNCGRTCYCIAGQLECSE 1494
Score = 33.9 bits (76), Expect = 4.3
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 15/95 (15%)
Query: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCY--CPKG---LLEQAGGCIPPEECNCW 4481
+ + CG+ A C L Q L GCY CP L E C+ EC+C+
Sbjct: 1408 WHYEPCGTVTAKTCKDQLVGQKFSSL---LEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1464
Query: 4482 HTSAAGAGMTLAPGDRLQLGC-KECECRRGELHCT 4515
+ AG ++ C + C C G+L C+
Sbjct: 1465 YNDVIPAGGV------IEDNCGRTCYCIAGQLECS 1493
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.504
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 295,510,154
Number of Sequences: 37866
Number of extensions: 19003744
Number of successful extensions: 91962
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 734
Number of HSP's that attempted gapping in prelim test: 55827
Number of HSP's gapped (non-prelim): 23144
length of query: 5147
length of database: 18,247,518
effective HSP length: 124
effective length of query: 5023
effective length of database: 13,552,134
effective search space: 68072369082
effective search space used: 68072369082
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.