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Search of human proteins with 51479158
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51479158 ataxin 1 [Homo sapiens]
(815 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189491748 ataxin 1 [Homo sapiens] 1634 0.0
gi|51479158 ataxin 1 [Homo sapiens] 1634 0.0
gi|212549561 ataxin 1-like [Homo sapiens] 257 3e-68
gi|55750053 atrophin-1 [Homo sapiens] 74 4e-13
gi|55750041 atrophin-1 [Homo sapiens] 74 4e-13
gi|4507379 TATA box binding protein [Homo sapiens] 70 1e-11
gi|110347429 mediator complex subunit 12 [Homo sapiens] 66 1e-10
gi|56549696 E1A binding protein p400 [Homo sapiens] 65 3e-10
gi|93141033 PAX interacting protein 1 [Homo sapiens] 65 3e-10
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 64 6e-10
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 64 6e-10
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 64 7e-10
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 62 2e-09
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 62 2e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 62 2e-09
gi|33286444 mastermind-like 2 [Homo sapiens] 62 3e-09
gi|55956910 meningioma 1 [Homo sapiens] 62 3e-09
gi|38158015 mastermind-like 3 [Homo sapiens] 62 3e-09
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 60 1e-08
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 60 1e-08
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 59 1e-08
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 59 1e-08
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 59 1e-08
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 59 1e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 57 5e-08
gi|40354197 THAP domain containing 11 [Homo sapiens] 57 7e-08
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 57 7e-08
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 56 1e-07
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] 56 1e-07
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 56 2e-07
>gi|189491748 ataxin 1 [Homo sapiens]
Length = 815
Score = 1634 bits (4230), Expect = 0.0
Identities = 815/815 (100%), Positives = 815/815 (100%)
Query: 1 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH 60
MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH
Sbjct: 1 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH 60
Query: 61 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY 120
GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY
Sbjct: 61 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY 120
Query: 121 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL 180
AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL
Sbjct: 121 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL 180
Query: 181 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP 240
LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP
Sbjct: 181 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP 240
Query: 241 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF 300
PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF
Sbjct: 241 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF 300
Query: 301 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH 360
VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH
Sbjct: 301 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH 360
Query: 361 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK 420
VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK
Sbjct: 361 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK 420
Query: 421 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ 480
PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ
Sbjct: 421 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ 480
Query: 481 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT 540
HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT
Sbjct: 481 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT 540
Query: 541 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ 600
QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ
Sbjct: 541 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ 600
Query: 601 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC 660
SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC
Sbjct: 601 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC 660
Query: 661 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR 720
CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR
Sbjct: 661 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR 720
Query: 721 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR 780
HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR
Sbjct: 721 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR 780
Query: 781 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK 815
KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
Sbjct: 781 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK 815
>gi|51479158 ataxin 1 [Homo sapiens]
Length = 815
Score = 1634 bits (4230), Expect = 0.0
Identities = 815/815 (100%), Positives = 815/815 (100%)
Query: 1 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH 60
MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH
Sbjct: 1 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH 60
Query: 61 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY 120
GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY
Sbjct: 61 GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQY 120
Query: 121 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL 180
AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL
Sbjct: 121 AHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTL 180
Query: 181 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP 240
LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP
Sbjct: 181 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPP 240
Query: 241 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF 300
PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF
Sbjct: 241 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHF 300
Query: 301 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH 360
VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH
Sbjct: 301 VPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRH 360
Query: 361 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK 420
VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK
Sbjct: 361 VVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGK 420
Query: 421 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ 480
PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ
Sbjct: 421 PGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQ 480
Query: 481 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT 540
HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT
Sbjct: 481 HLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVT 540
Query: 541 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ 600
QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ
Sbjct: 541 QAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQ 600
Query: 601 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC 660
SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC
Sbjct: 601 SAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSC 660
Query: 661 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR 720
CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR
Sbjct: 661 CPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSR 720
Query: 721 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR 780
HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR
Sbjct: 721 HRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESR 780
Query: 781 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK 815
KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK
Sbjct: 781 KLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK 815
>gi|212549561 ataxin 1-like [Homo sapiens]
Length = 689
Score = 257 bits (657), Expect = 3e-68
Identities = 248/843 (29%), Positives = 349/843 (41%), Gaps = 182/843 (21%)
Query: 1 MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNP-GGRGHGGGR 59
MK ERS ECLPPKKR++P TS + + + W G G+ G R
Sbjct: 1 MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQAGAR 60
Query: 60 HGPAGTSVE----LGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLP----AAYATPQP 111
G E L + Q L+K +SP P V ++ P A+ P
Sbjct: 61 VSLGGDGAEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHP 120
Query: 112 GTPVSPVQYAHLPHT-FQFIGSSQYSGTYA---SFIPSQLIPPTANPVTSAVASAAGATT 167
G P+ YA LP T QFIGS YS YA +F+PS L+ P+AN TS +
Sbjct: 121 GIHYPPLHYAQLPSTSLQFIGSP-YSLPYAVPPNFLPSPLLSPSANLATSHLP------- 172
Query: 168 PSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHL 227
Y++LLA TP +A
Sbjct: 173 -----HFVPYASLLAE----GATPPPQAPSPAHS-------------------------F 198
Query: 228 SRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPS 287
++AP +P P H S+ P + +P +P++ + +TL PP
Sbjct: 199 NKAPSATSPSGQLPH------HSSTQPLDL----APGRMPIYYQMSRLPAGYTLHETPP- 247
Query: 288 QVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKA 347
A + P+E+ E++ + +E N +S +P+S G G
Sbjct: 248 ------AGASPVLTPQESQSALEAAAANGGQRPRE-RNLVRRESEALDSPNSKGEGQGL- 299
Query: 348 GGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQ-------- 399
VP VV R V + TP DLEVQ+
Sbjct: 300 ----VP--------VVECVVDGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQ 347
Query: 400 -----ATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATA-- 452
A R+ PS LN L P H+ + SA P + + A
Sbjct: 348 DYRVVAAQRKEEPSPLN----LSHHTPDHQG---------EGRGSARNPAELAEKSQARG 394
Query: 453 FYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSS 512
FY + + + + + G+L V GT L+PVGS + AS
Sbjct: 395 FYPQSHQEPVKHRPLPKAMVVANGNL----VPTGTDSGLLPVGSEILVASSLD------- 443
Query: 513 PQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPP 572
VQA+ P + P + LP
Sbjct: 444 -----------------------------------VQARATFPDKEPTPPPITSSH-LPS 467
Query: 573 YFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFA 632
+FMKG+IIQLA GELK+VEDL+T+DF++SAE+S LKIDSSTV I++S PG ++ F
Sbjct: 468 HFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFV 527
Query: 633 VGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKN 692
VGE +++VS+EV E+PFFV+GQGWSSC P RT+QLF LPC +L VGDVCIS++L++L +
Sbjct: 528 VGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTTQLFSLPCHRLQVGDVCISISLQSLNS 587
Query: 693 GSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGL 752
SV + P+ L R E+ GS ++ G+ +
Sbjct: 588 NSVSQASCAPPSQ----------LGPPR----ERPERTVLGSRELCDSEGKSQ------- 626
Query: 753 PAAPFLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSN 812
PA +EPS+P + + W AP ++ +E L +PS IPQEVK+ IEGRSN
Sbjct: 627 PAGEGSRVVEPSQPESGAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSN 686
Query: 813 VGK 815
GK
Sbjct: 687 AGK 689
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.3 bits (181), Expect = 4e-13
Identities = 128/525 (24%), Positives = 180/525 (34%), Gaps = 96/525 (18%)
Query: 13 PPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQ 72
PP K P T+ P+ P + T LP P R P G + L
Sbjct: 271 PPTK---PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQ-PLP 326
Query: 73 QGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGS 132
+ A+ G+ PP P P P + P P+++ + + +
Sbjct: 327 GHLPSPHAMGQGMGGLPPG-PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA 385
Query: 133 SQYSGTYAS----FIPSQLIP--------PTANPVTSAVASAAGATTPSQRSQLEA---- 176
S S + +S F SQ +P PT+ V++ + PSQ +
Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPP 445
Query: 177 --YSTLLANMGSL---------SQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
Y LLAN + +Q+ H QQQQQ Q QQQQQQQQQQQQ
Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ--QQQQQQQQQQQQH 503
Query: 226 HLSRAPGLITPGS-PPPAQ--QNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLT 282
H + P PG+ P P + + + H + + G P P HL P
Sbjct: 504 HGNSGPP--PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP---------- 551
Query: 283 LGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAP----- 337
P SQV Y+ +G + P ++ + SS Q + + + Y P
Sbjct: 552 --PHSQV--SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 338 --SSADLGL-------GKAGGKSV----PHPYESRHVVVHPSPSDYSSRDPSGVRASVMV 384
SSA L AG K+ P PY R PSP Y + P G +
Sbjct: 608 TTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR----APSPGAYKTATPPGYKPGSPP 663
Query: 385 LPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPL 444
+ TP + T A P T KPG + P + S P
Sbjct: 664 SFRTGTPPG----YRGTSPPAGPGTF---------KPGSPTVGPGPLPPAGPSGLPSLPP 710
Query: 445 PVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQP 489
P PA+ PP+ Q+ A Y P+ V P P
Sbjct: 711 PPAAPASG------PPLSATQIKQEPAEEY--ETPESPVPPARSP 747
Score = 37.7 bits (86), Expect = 0.043
Identities = 125/579 (21%), Positives = 170/579 (29%), Gaps = 115/579 (19%)
Query: 50 PGGRGH--GGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYA 107
PGG G G GP G G +G + G + PP+ P SV + A
Sbjct: 221 PGGTGGVLSGPPMGPKGG----GAASSVG---GPNGGKQHPPPTTPISVSSS----GASG 269
Query: 108 TPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAG--- 164
P P +PV +LP S+ + P+ PP P+ +A AS G
Sbjct: 270 APPTKPPTTPVGGGNLP-------SAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA 322
Query: 165 -------------------------------------------ATTPSQRSQLEAYSTLL 181
A P R + S+
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 182 ANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQ-----QQQQQQQQQQQQQHLSRAPGLITP 236
A S S + A Q H Q + Q S+A P
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP 442
Query: 237 GSPPPAQQ---NQYVHISSSPQNTG--RTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVM 291
PPP + N H P +TG TA PP + H H HQ Q
Sbjct: 443 PPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP-VSTHHHHHQQQQQQQQQQQQQQQQQQ 501
Query: 292 QYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYG------APSSADLGLG 345
Q+ + P E A ++ + R Y P + +
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHA--HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYS 559
Query: 346 KAGGKSVPHPYESR---------HVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLE 396
+AG P S + HPSP S+ P G +P T +A L
Sbjct: 560 QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP----SQGPQGAPYPFPPVPTVTTSSATLS 615
Query: 397 VQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAG 456
AT + S K+ G P + A SP T +P G P +F G
Sbjct: 616 TVIAT---VASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP---GSP-PSFRTG 668
Query: 457 TQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFA 516
T P GY A V PG P P G + + + PA S P +
Sbjct: 669 TPP---GYRGTSPPAGPGTFKPGSPTVGPGPLP---PAGPSGLPSLPPPPAAPASGPPLS 722
Query: 517 AVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLP 555
A P E PE+ V A P+ + +P
Sbjct: 723 ATQ----IKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Score = 35.8 bits (81), Expect = 0.16
Identities = 92/430 (21%), Positives = 161/430 (37%), Gaps = 86/430 (20%)
Query: 89 PPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIP--SQ 146
PP+ P +P +LP A P G P+S Q P + +Y + P S
Sbjct: 698 PPAGPSGLP---SLPPPPAAPASGPPLSATQIKQEP-------AEEYETPESPVPPARSP 747
Query: 147 LIPPTANPVTSAVASAAGATTPSQR-----SQLEAY------STLLANMGSLSQTPGHKA 195
PP V S + +A R ++ + Y S L L + +A
Sbjct: 748 SPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREA 807
Query: 196 EQQ-----QQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSP----PPAQQNQ 246
EQ+ ++++++++++ + ++++++ ++ + RAP P PP +
Sbjct: 808 EQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGS 867
Query: 247 YVHISSSPQNTG------RTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQY------- 293
V ++ P G RT S A P + P P + LG ++ Y
Sbjct: 868 AV--ATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYS 925
Query: 294 ADSGSHFVPREATKKAESSRLQQAIQAK----EVLNG----EMEKSRRYGAPSSADLGLG 345
+D + REA ++ RL+ + K E L+G ++ R+G GL
Sbjct: 926 SDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHG-------GLA 978
Query: 346 KAGGKSVPHPY---------ESRHVVVHPSPS-----DYSSRDPSGVRASVMVLPNSNTP 391
G HP+ E + + P+ Y+ R + + + V N P
Sbjct: 979 LQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDP 1038
Query: 392 AADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVG--LP 449
A L++ T S ++ S LHL H+ A+ H + H +PL G L
Sbjct: 1039 LARLQMLNVTPHHHQHSHIH--SHLHL----HQQDAI--HAASASVHPLIDPLASGSHLT 1090
Query: 450 ATAFYAGTQP 459
+ AGT P
Sbjct: 1091 RIPYPAGTLP 1100
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.3 bits (181), Expect = 4e-13
Identities = 128/525 (24%), Positives = 180/525 (34%), Gaps = 96/525 (18%)
Query: 13 PPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQ 72
PP K P T+ P+ P + T LP P R P G + L
Sbjct: 271 PPTK---PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQ-PLP 326
Query: 73 QGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGS 132
+ A+ G+ PP P P P + P P+++ + + +
Sbjct: 327 GHLPSPHAMGQGMGGLPPG-PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA 385
Query: 133 SQYSGTYAS----FIPSQLIP--------PTANPVTSAVASAAGATTPSQRSQLEA---- 176
S S + +S F SQ +P PT+ V++ + PSQ +
Sbjct: 386 SSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPP 445
Query: 177 --YSTLLANMGSL---------SQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
Y LLAN + +Q+ H QQQQQ Q QQQQQQQQQQQQ
Sbjct: 446 PPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ--QQQQQQQQQQQQH 503
Query: 226 HLSRAPGLITPGS-PPPAQ--QNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLT 282
H + P PG+ P P + + + H + + G P P HL P
Sbjct: 504 HGNSGPP--PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP---------- 551
Query: 283 LGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAP----- 337
P SQV Y+ +G + P ++ + SS Q + + + Y P
Sbjct: 552 --PHSQV--SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607
Query: 338 --SSADLGL-------GKAGGKSV----PHPYESRHVVVHPSPSDYSSRDPSGVRASVMV 384
SSA L AG K+ P PY R PSP Y + P G +
Sbjct: 608 TTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR----APSPGAYKTATPPGYKPGSPP 663
Query: 385 LPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPL 444
+ TP + T A P T KPG + P + S P
Sbjct: 664 SFRTGTPPG----YRGTSPPAGPGTF---------KPGSPTVGPGPLPPAGPSGLPSLPP 710
Query: 445 PVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQP 489
P PA+ PP+ Q+ A Y P+ V P P
Sbjct: 711 PPAAPASG------PPLSATQIKQEPAEEY--ETPESPVPPARSP 747
Score = 37.7 bits (86), Expect = 0.043
Identities = 125/579 (21%), Positives = 170/579 (29%), Gaps = 115/579 (19%)
Query: 50 PGGRGH--GGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYA 107
PGG G G GP G G +G + G + PP+ P SV + A
Sbjct: 221 PGGTGGVLSGPPMGPKGG----GAASSVG---GPNGGKQHPPPTTPISVSSS----GASG 269
Query: 108 TPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAG--- 164
P P +PV +LP S+ + P+ PP P+ +A AS G
Sbjct: 270 APPTKPPTTPVGGGNLP-------SAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA 322
Query: 165 -------------------------------------------ATTPSQRSQLEAYSTLL 181
A P R + S+
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
Query: 182 ANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQ-----QQQQQQQQQQQQQHLSRAPGLITP 236
A S S + A Q H Q + Q S+A P
Sbjct: 383 AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP 442
Query: 237 GSPPPAQQ---NQYVHISSSPQNTG--RTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVM 291
PPP + N H P +TG TA PP + H H HQ Q
Sbjct: 443 PPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP-VSTHHHHHQQQQQQQQQQQQQQQQQQ 501
Query: 292 QYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYG------APSSADLGLG 345
Q+ + P E A ++ + R Y P + +
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHA--HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYS 559
Query: 346 KAGGKSVPHPYESR---------HVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLE 396
+AG P S + HPSP S+ P G +P T +A L
Sbjct: 560 QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP----SQGPQGAPYPFPPVPTVTTSSATLS 615
Query: 397 VQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAG 456
AT + S K+ G P + A SP T +P G P +F G
Sbjct: 616 TVIAT---VASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP---GSP-PSFRTG 668
Query: 457 TQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFA 516
T P GY A V PG P P G + + + PA S P +
Sbjct: 669 TPP---GYRGTSPPAGPGTFKPGSPTVGPGPLP---PAGPSGLPSLPPPPAAPASGPPLS 722
Query: 517 AVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLP 555
A P E PE+ V A P+ + +P
Sbjct: 723 ATQ----IKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Score = 35.8 bits (81), Expect = 0.16
Identities = 92/430 (21%), Positives = 161/430 (37%), Gaps = 86/430 (20%)
Query: 89 PPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIP--SQ 146
PP+ P +P +LP A P G P+S Q P + +Y + P S
Sbjct: 698 PPAGPSGLP---SLPPPPAAPASGPPLSATQIKQEP-------AEEYETPESPVPPARSP 747
Query: 147 LIPPTANPVTSAVASAAGATTPSQR-----SQLEAY------STLLANMGSLSQTPGHKA 195
PP V S + +A R ++ + Y S L L + +A
Sbjct: 748 SPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREA 807
Query: 196 EQQ-----QQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSP----PPAQQNQ 246
EQ+ ++++++++++ + ++++++ ++ + RAP P PP +
Sbjct: 808 EQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGS 867
Query: 247 YVHISSSPQNTG------RTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQY------- 293
V ++ P G RT S A P + P P + LG ++ Y
Sbjct: 868 AV--ATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYS 925
Query: 294 ADSGSHFVPREATKKAESSRLQQAIQAK----EVLNG----EMEKSRRYGAPSSADLGLG 345
+D + REA ++ RL+ + K E L+G ++ R+G GL
Sbjct: 926 SDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHG-------GLA 978
Query: 346 KAGGKSVPHPY---------ESRHVVVHPSPS-----DYSSRDPSGVRASVMVLPNSNTP 391
G HP+ E + + P+ Y+ R + + + V N P
Sbjct: 979 LQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDP 1038
Query: 392 AADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVG--LP 449
A L++ T S ++ S LHL H+ A+ H + H +PL G L
Sbjct: 1039 LARLQMLNVTPHHHQHSHIH--SHLHL----HQQDAI--HAASASVHPLIDPLASGSHLT 1090
Query: 450 ATAFYAGTQP 459
+ AGT P
Sbjct: 1091 RIPYPAGTLP 1100
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 69.7 bits (169), Expect = 1e-11
Identities = 62/174 (35%), Positives = 76/174 (43%), Gaps = 24/174 (13%)
Query: 154 PVTSAVASAAGATTPSQR--SQLEAYSTLLA-----NMGSLSQTPGHKAEQQQQQQQQQQ 206
P +AS GA TP S + Y T L N SLS + +QQQQQQQQQQ
Sbjct: 9 PYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQ 68
Query: 207 QQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAI 266
QQ Q QQQQQQQQQQQQQQ + QQ Q V ++ Q+T + A+
Sbjct: 69 QQQQQQQQQQQQQQQQQQQQQQQ-------------QQQQAVAAAAVQQSTSQQATQGTS 115
Query: 267 PVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVP-REATKKAESSRLQQAIQ 319
Q TLT P Y + P AT +ESS + +Q
Sbjct: 116 G---QAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQ 166
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 66.2 bits (160), Expect = 1e-10
Identities = 44/110 (40%), Positives = 52/110 (47%), Gaps = 7/110 (6%)
Query: 145 SQLIPPTANPVTSAVASAA--GATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQ- 201
S + P +A V + V S A Q+ Q + Q H +QQQQQ
Sbjct: 2028 STMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQI 2087
Query: 202 ----QQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQY 247
QQQQQQQ Q QQQQQQQQQQQQQQH + P P P Q Q+
Sbjct: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQF 2137
Score = 62.8 bits (151), Expect = 1e-09
Identities = 32/51 (62%), Positives = 35/51 (68%)
Query: 194 KAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQ 244
+ +QQQQQQQQQQQQ Q QQQQQQQQQ QQQQ AP P S P Q+
Sbjct: 2089 RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQR 2139
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/58 (46%), Positives = 29/58 (50%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQ 246
Q + +QQQQQQQQQQQQ Q QQQQQQQ Q P G QQ Q
Sbjct: 2093 QQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ 2150
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/60 (46%), Positives = 31/60 (51%), Gaps = 18/60 (30%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQ------------------QQQQQQHLSRA 230
Q + +QQQQQQQQQQQQ QHQQQQQQQ QQ QQQ + A
Sbjct: 2094 QQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAA 2153
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 65.1 bits (157), Expect = 3e-10
Identities = 122/513 (23%), Positives = 175/513 (34%), Gaps = 77/513 (15%)
Query: 97 PVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVT 156
PVA P A TP +P Q H + +GS T + S VT
Sbjct: 2620 PVA---PGALTTPGGS---APAQVVHTQPPPRAVGSP---ATATPDLVSMATTQGVRAVT 2670
Query: 157 SAVASAAGAT------TPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQ 210
S ASA T TP++ + + + TP H +QQQQQQQQQQ Q
Sbjct: 2671 SVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQ 2730
Query: 211 HQQQQQQQQQQQQQQHLS---------------------RAPGLITPGSPPPAQQNQYVH 249
QQQQQQQQQQQQQQ + +A G +TP Q+ +
Sbjct: 2731 QQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQM 2790
Query: 250 ISSSPQNTGRTASP-PAIPVHL---HPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREA 305
P ++A P P V + P Q P T+ P + + ++
Sbjct: 2791 PPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARL 2850
Query: 306 TKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHP 365
T + +S+LQ G+M+ AP A + L K SVP VV P
Sbjct: 2851 T-RVPTSQLQ--------AQGQMQTQ----APQPAQVALAKPPVVSVP-----AAVVSSP 2892
Query: 366 SPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRS 425
+ P V + + A V Q H + L K + +
Sbjct: 2893 GVTTL----PMNVAGISVAIGQPQKAAGQTVVAQPVHMQ---QLLKLKQQAVQQQKAIQP 2945
Query: 426 YALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLS---GQQQAITYAGSLPQHL 482
A +Q +A + G YA +L+ Q Q + A + +
Sbjct: 2946 QAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQI 3005
Query: 483 VI---PGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALV 539
+ P PV S AS + A SPQ A+ T T A + +
Sbjct: 3006 QVAKLPQVVQQQTPVASIQQVASASQQA----SPQTVAL--TQATAAGQQVQMIPAVTAT 3059
Query: 540 TQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPP 572
Q ++Q Q+ + +P A P P
Sbjct: 3060 AQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVP 3092
Score = 38.9 bits (89), Expect = 0.019
Identities = 67/290 (23%), Positives = 101/290 (34%), Gaps = 35/290 (12%)
Query: 88 SPPSAPRSVPVATTLPAAYATPQ-------------PGTPVSPVQYAHLPH--TFQFIGS 132
+PP V V T+ P +PQ GT V+ +Q A L T Q
Sbjct: 2802 APPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQ 2861
Query: 133 SQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQ----------RSQLEAYSTLLA 182
Q L P V +AV S+ G TT + Q A T++A
Sbjct: 2862 GQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVA 2921
Query: 183 NMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQ------QQHLSRA--PGLI 234
+ Q K + QQQ+ Q Q Q QQ+ QQ QQ ++ A P L
Sbjct: 2922 QPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALK 2981
Query: 235 TPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTM--IPHTLTLGPPSQVVMQ 292
T P Q Q + + Q + A P + P ++ + P V +
Sbjct: 2982 TQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALT 3041
Query: 293 YADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADL 342
A + V A + +QQ + ++V+ + GAP+ A +
Sbjct: 3042 QATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQV 3091
Score = 30.8 bits (68), Expect = 5.3
Identities = 61/246 (24%), Positives = 91/246 (36%), Gaps = 27/246 (10%)
Query: 185 GSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQ 244
G + TP Q Q+Q QQQ+ Q L + PG + P P A
Sbjct: 514 GGMPPTP---QAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAAL 570
Query: 245 NQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVV----MQYADSGSHF 300
+ + + PQ + IPV +T P+ PPS + Q A H
Sbjct: 571 SSALQFAQQPQ-VVEAQTQLQIPV-----KTQQPNVPIPAPPSSQLPIPPSQPAQLALH- 623
Query: 301 VPREATKKAESSRLQQAIQ--AKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYES 358
VP + ++S+L Q A L + P+S+ L G S P P +
Sbjct: 624 VPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSG-SGPGPSPA 682
Query: 359 RHVVVH-PSP------SDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLN 411
R V+ PS S +SR P GV AS P S PA + Q + ++ +
Sbjct: 683 RSSPVNRPSSATNKALSPVTSRTP-GVVASAPTKPQS--PAQNATSSQDSSQDTLTEQIT 739
Query: 412 DKSGLH 417
++ +H
Sbjct: 740 LENQVH 745
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 64.7 bits (156), Expect = 3e-10
Identities = 56/171 (32%), Positives = 65/171 (38%), Gaps = 20/171 (11%)
Query: 109 PQPGTPVSPV-------QYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTA--NPVTSAV 159
P P P P Q AH PH Q+S F QL PP P
Sbjct: 439 PYPQQPPHPFSQQQQQQQQAH-PH--------QFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
Query: 160 ASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQ 219
Q QL+ + + L Q +QQQQQ QQQQ Q HQQQQQQQ
Sbjct: 490 PFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQM 549
Query: 220 QQQQQQHLSRAPGLITPGSPP--PAQQNQYVHISSSPQNTGRTASPPAIPV 268
Q Q HLS+ + PP P QQ Q SPQ PA+ +
Sbjct: 550 QSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEI 600
Score = 48.9 bits (115), Expect = 2e-05
Identities = 49/191 (25%), Positives = 75/191 (39%), Gaps = 29/191 (15%)
Query: 85 LDYSPPSAPRSVPVATTLP----------AAYATPQPGTPVSPVQYAHLPHTFQFIGSSQ 134
L+++P P+ LP A P PG + P +L Q + SS+
Sbjct: 264 LNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQNLQSSE 323
Query: 135 YSGTYASFIPS--------------QLIPPT-----ANPVTSAVASAAGATTPSQRSQLE 175
S A++ P+ Q+ P+ +++ + SQ+
Sbjct: 324 RSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTN 383
Query: 176 AYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT 235
A + L + + +T + +QQ QQQQQQ Q QQ Q QQQQQQ +S+ P
Sbjct: 384 ANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQ 443
Query: 236 PGSPPPAQQNQ 246
P P QQ Q
Sbjct: 444 PPHPFSQQQQQ 454
Score = 43.5 bits (101), Expect = 8e-04
Identities = 32/84 (38%), Positives = 36/84 (42%), Gaps = 7/84 (8%)
Query: 168 PSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQH- 226
P Q QL+ + Q P H QQ QQQQQQ H HQ QQQ Q QQQ H
Sbjct: 421 PQQIMQLQQQQQQQISQQPYPQQPPHPFSQQ---QQQQQQAHPHQFSQQQLQFPQQQLHP 477
Query: 227 ---LSRAPGLITPGSPPPAQQNQY 247
L R + P A Q Q+
Sbjct: 478 PQQLHRPQQQLQPFQQQHALQQQF 501
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 63.9 bits (154), Expect = 6e-10
Identities = 48/127 (37%), Positives = 60/127 (47%), Gaps = 24/127 (18%)
Query: 150 PTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQH 209
P P S+ A +QRS+ LL++ + +QQQQQQQQQQQQ
Sbjct: 1208 PMMQPQVSSQQGFLNAQMVAQRSR-----ELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQ 1262
Query: 210 QHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASP--PAIP 267
Q QQQQQQQQQQQQ Q SPPP ++++SP G A P P P
Sbjct: 1263 QQQQQQQQQQQQQQTQAF----------SPPP-------NVTASPSMDGLLAGPTMPQAP 1305
Query: 268 VHLHPHQ 274
P+Q
Sbjct: 1306 PQQFPYQ 1312
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 63.9 bits (154), Expect = 6e-10
Identities = 40/82 (48%), Positives = 47/82 (57%), Gaps = 15/82 (18%)
Query: 195 AEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSP 254
A QQQQQQQQQQ Q QQQQQQQQQQQQQQ ++A SPPP ++++SP
Sbjct: 1240 AMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQA------FSPPP-------NVTASP 1286
Query: 255 QNTGRTASP--PAIPVHLHPHQ 274
G A P P P P+Q
Sbjct: 1287 SMDGLLAGPTMPQAPPQQFPYQ 1308
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 63.5 bits (153), Expect = 7e-10
Identities = 64/230 (27%), Positives = 82/230 (35%), Gaps = 35/230 (15%)
Query: 27 EEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVE----LGLQQGIGLHKALS 82
E T+ + + G + L G G + V L LQQ L A
Sbjct: 4 ESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQ 63
Query: 83 TGLDY------SPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYS 136
L SP S+ + P+ + A TPQ TP Q
Sbjct: 64 LLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ----------------- 106
Query: 137 GTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAE 196
+ Q++ P A+ A Q+ E Y + + +
Sbjct: 107 -----ILQQQVLSPQQ---LQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 158
Query: 197 QQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQ 246
QQQQQQQQQQQQ Q QQQQQQQQQQQQQQ + PG QQ Q
Sbjct: 159 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 208
Score = 58.9 bits (141), Expect = 2e-08
Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYV 248
Q + +QQQQQQQQQQQQH +Q ++QQQQQQQQQ L+ A L+ QQ Q
Sbjct: 172 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA-AQQLVFQQQLLQMQQLQQQ 230
Query: 249 HISSSPQNTGRTASPP---AIPVHLHPHQTMIP 278
S Q G + PP A+PV P + P
Sbjct: 231 QHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 263
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/58 (58%), Positives = 36/58 (62%), Gaps = 9/58 (15%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQ 246
Q + +QQQQQQQQQQQQ Q QQQQQQQQQQQQQQH PG QQ Q
Sbjct: 63 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQH---------PGKQAKEQQQQ 111
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/51 (62%), Positives = 34/51 (66%)
Query: 196 EQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQ 246
+QQQQQQQQQQQQ Q QQQQQQQQQQQQQQ + PG QQ Q
Sbjct: 66 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 116
Score = 58.9 bits (141), Expect = 2e-08
Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYV 248
Q + +QQQQQQQQQQQQH +Q ++QQQQQQQQQ L+ A L+ QQ Q
Sbjct: 80 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA-AQQLVFQQQLLQMQQLQQQ 138
Query: 249 HISSSPQNTGRTASPP---AIPVHLHPHQTMIP 278
S Q G + PP A+PV P + P
Sbjct: 139 QHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 171
Score = 47.0 bits (110), Expect = 7e-05
Identities = 27/60 (45%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 167 TPSQ-RSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
+P Q ++ L+ ++ L + + EQ Q QQQQQ Q QQQQQQQQQQQQQQ
Sbjct: 22 SPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ 81
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/58 (58%), Positives = 36/58 (62%), Gaps = 9/58 (15%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQ 246
Q + +QQQQQQQQQQQQ Q QQQQQQQQQQQQQQH PG QQ Q
Sbjct: 180 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQH---------PGKQAKEQQQQ 228
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/51 (62%), Positives = 34/51 (66%)
Query: 196 EQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQ 246
+QQQQQQQQQQQQ Q QQQQQQQQQQQQQQ + PG QQ Q
Sbjct: 183 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 233
Score = 58.9 bits (141), Expect = 2e-08
Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYV 248
Q + +QQQQQQQQQQQQH +Q ++QQQQQQQQQ L+ A L+ QQ Q
Sbjct: 197 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA-AQQLVFQQQLLQMQQLQQQ 255
Query: 249 HISSSPQNTGRTASPP---AIPVHLHPHQTMIP 278
S Q G + PP A+PV P + P
Sbjct: 256 QHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288
Score = 47.0 bits (110), Expect = 7e-05
Identities = 27/60 (45%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 167 TPSQ-RSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
+P Q ++ L+ ++ L + + EQ Q QQQQQ Q QQQQQQQQQQQQQQ
Sbjct: 139 SPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQ 198
Score = 34.7 bits (78), Expect = 0.37
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 156 TSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQ 215
T AV + TP + + L + S Q +QQ QQQQ Q +++QQ
Sbjct: 109 TFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 168
Query: 216 QQ------QQQQQQQQ 225
+Q QQQQQQQQ
Sbjct: 169 EQLHLQLLQQQQQQQQ 184
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 62.4 bits (150), Expect = 2e-09
Identities = 76/263 (28%), Positives = 101/263 (38%), Gaps = 30/263 (11%)
Query: 193 HKAEQQQQQQQQQQQQH--QHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHI 250
H QQQ QQQQQQ Q Q Q QQQQQQQQQQQQ +A P PP QQ Q
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPS 283
Query: 251 SSSPQ------NTGRTASPP---AIPVHLHPHQTMIPHTLTLGPPSQV-----VMQYADS 296
+ PQ +T PP PV + + P + T SQ M Y
Sbjct: 284 QALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQP 343
Query: 297 GSHFV---------PREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKA 347
FV P + + + + +Q A A+ V G SS G
Sbjct: 344 PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQ 403
Query: 348 GGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASP 407
+S+P P + P P SS+ S V + P+S P+ + Q+ +P
Sbjct: 404 TPQSMPPPPQP-----SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTP 458
Query: 408 STLNDKSGLHLGKPGHRSYALSP 430
+ S L P + S +SP
Sbjct: 459 QNFSVPSPGPLNTPVNPSSVMSP 481
Score = 48.5 bits (114), Expect = 2e-05
Identities = 104/475 (21%), Positives = 174/475 (36%), Gaps = 82/475 (17%)
Query: 154 PVTSAVA--SAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQH 211
P TS +A S A +T + ++QL+ L QQQQQQQQ QQQ Q
Sbjct: 131 PGTSGMAPHSMAVVSTATPQTQLQLQQVAL---------------QQQQQQQQFQQQQQA 175
Query: 212 QQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLH 271
QQQQQQQQQQQ ++ A Q Q+ + Q L
Sbjct: 176 ALQQQQQQQQQQQFQAQQS-----------AMQQQFQAVVQQQQ-------------QLQ 211
Query: 272 PHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGE---M 328
Q H + L +Q +Q + + ++ + + QQ Q ++ L +
Sbjct: 212 QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ 271
Query: 329 EKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNS 388
+ + P + +++P + H H P + P + P S
Sbjct: 272 QPPMQQPQPPPS---------QALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQS 322
Query: 389 NTPAADLEVQQATHR--EASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPV 446
T + Q + P ++ + + +P + T +QT +A P
Sbjct: 323 QTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAP- 381
Query: 447 GLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAP 506
G+ + + P++ S QQ T PQ + P QP P + S
Sbjct: 382 GVQVSQ----SSLPMLSSPSPGQQVQT-----PQSMP-PPPQPSPQP-----GQPSSQPN 426
Query: 507 AIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPV-VQSVASPAA 565
+ V+S P A P +F+ + P+ +P T + ++ PV SV SPA
Sbjct: 427 SNVSSGP--APSPSSFLPSPSPQPSQ-SPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAG 483
Query: 566 APPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIED 620
+ ++ + QL+ K +E L+ I + + D K D S ++ + D
Sbjct: 484 SSQAEEQQYL-DKLKQLS----KYIEPLRR--MINKIDKNEDRKKDLSKMKSLLD 531
Score = 30.4 bits (67), Expect = 6.9
Identities = 42/185 (22%), Positives = 78/185 (42%), Gaps = 29/185 (15%)
Query: 93 PRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTA 152
P+S+P P +PQPG P S P++ SS + + +SF+PS P+
Sbjct: 405 PQSMP-----PPPQPSPQPGQPSSQ------PNSNV---SSGPAPSPSSFLPSPSPQPSQ 450
Query: 153 NPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQ 212
+PVT+ +P + S++++ GS +AE+QQ + +Q +
Sbjct: 451 SPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS------SQAEEQQYLDKLKQLSKYIE 504
Query: 213 QQQQQ----QQQQQQQQHLSRAPGLI----TPGSPPPAQQNQYVHIS-SSPQNTGRTASP 263
++ + + +++ LS+ L+ P P + Q I+ +N +P
Sbjct: 505 PLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTP 564
Query: 264 PAIPV 268
P PV
Sbjct: 565 PPPPV 569
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 61.6 bits (148), Expect = 3e-09
Identities = 39/103 (37%), Positives = 48/103 (46%), Gaps = 6/103 (5%)
Query: 187 LSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLS------RAPGLITPGSPP 240
L T + +QQQQQQQQQQQQ Q QQQQQQQQQQQQQ +S + +
Sbjct: 584 LHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQ 643
Query: 241 PAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTL 283
QQ Q Q + P + P P Q ++ L L
Sbjct: 644 QQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPL 686
Score = 61.6 bits (148), Expect = 3e-09
Identities = 35/75 (46%), Positives = 41/75 (54%)
Query: 170 QRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSR 229
Q+ Q + S++ A Q+ +QQQQQQQQQQQQ Q QQQQQQQQQQ Q
Sbjct: 614 QQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQS 673
Query: 230 APGLITPGSPPPAQQ 244
P SP P QQ
Sbjct: 674 LPSQPLLRSPLPLQQ 688
Score = 60.5 bits (145), Expect = 6e-09
Identities = 36/64 (56%), Positives = 38/64 (59%)
Query: 183 NMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPA 242
N SL + +QQQQQQQQQQQQ Q QQQQQQQQQQQQQQ A S A
Sbjct: 579 NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638
Query: 243 QQNQ 246
QQ Q
Sbjct: 639 QQQQ 642
Score = 47.8 bits (112), Expect = 4e-05
Identities = 46/152 (30%), Positives = 57/152 (37%), Gaps = 8/152 (5%)
Query: 107 ATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFI---PSQLIPPTANPVTSAVASAA 163
++P PG Q + + G S G + P L N A+
Sbjct: 494 SSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQ 553
Query: 164 GATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQ 223
G T P L +++ AN S P QQQQQQ Q QQQQQQQQQQQQ
Sbjct: 554 GNTKP-----LFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQ 608
Query: 224 QQHLSRAPGLITPGSPPPAQQNQYVHISSSPQ 255
QQ + S QQ Q S+ Q
Sbjct: 609 QQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ 640
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/188 (25%), Positives = 71/188 (37%), Gaps = 22/188 (11%)
Query: 107 ATPQPGTPVSPVQYAHLPHTFQFIGSSQYSG--TYASFIPSQLIPPTANPVTSAVASAAG 164
+TP+P P+ + + S+YS T QL PP+A P S SA
Sbjct: 351 STPRPSLPMEKI-----------VIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALS 399
Query: 165 ATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQ---QQQQHQHQQQQQQQQQQ 221
++P S ++ + G+ P + QQ +Q +QQH QQ QQQ Q
Sbjct: 400 TSSPIP-SVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQP 458
Query: 222 QQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASP-PAIPVHLHPHQTMIPHT 280
L + G SP P Q + S Q +SP P + + M +
Sbjct: 459 TNWSALPSSAG----PSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYM 514
Query: 281 LTLGPPSQ 288
GP +Q
Sbjct: 515 YKAGPSAQ 522
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 61.6 bits (148), Expect = 3e-09
Identities = 37/75 (49%), Positives = 39/75 (52%), Gaps = 16/75 (21%)
Query: 191 PGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQ----------------QQHLSRAPGLI 234
P H++ QQQQQQQQQQQQ Q QQQQQQQQQQQQ QQ R P L
Sbjct: 517 PDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLA 576
Query: 235 TPGSPPPAQQNQYVH 249
G P Q VH
Sbjct: 577 QLGHPGDVGQGGLVH 591
Score = 52.0 bits (123), Expect = 2e-06
Identities = 25/33 (75%), Positives = 25/33 (75%)
Query: 193 HKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
H A Q QQQQQQQ Q QQQQQQQQQQQQQQ
Sbjct: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQ 546
Score = 41.6 bits (96), Expect = 0.003
Identities = 105/439 (23%), Positives = 146/439 (33%), Gaps = 120/439 (27%)
Query: 34 PSDNHRVEGTAWLPGNPGGRG------HGGGRHGPAGTSVELGLQQGIGL---HKALSTG 84
P +H + GN GG HGG G G + LG Q H A S G
Sbjct: 102 PGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQG 161
Query: 85 LDYSPPSAPRSVP-VATTLPAAYATPQPGTPV--SPVQYAH---LP-------HTFQ--- 128
+ P P ++P ++ +++A P P P+ SP + A LP H+ +
Sbjct: 162 PESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRR 221
Query: 129 -----FIGSSQY-------SGTYASFIPS------------QLIPPTANPVTSAVASAAG 164
+ S +Y SG + F PS + +P A P SA+ AAG
Sbjct: 222 VTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAG 281
Query: 165 ATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQH--------------- 209
+ + + P + QQQQQ QQQQQQH
Sbjct: 282 ----------------MVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPV 325
Query: 210 -------------QHQQQ-----QQQQQQQQQQQHLSRAPG-LITPGSPPPAQQNQYVHI 250
Q QQ QQQ QQ QQ PG L+ S PPA
Sbjct: 326 GLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGE 385
Query: 251 SSSPQNTGRTASPP--------AIPVHLHPHQTMIPH-----TLTLGPPSQVVMQYADSG 297
+ +P + P P+H +++M P+ ++ PP Q Q
Sbjct: 386 AGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRL--- 442
Query: 298 SHFVPREATKKAESSRL----QQAIQAKEVLNGEMEKSRRYGAPS-SADLGLGKAGGKSV 352
HF A+ R + NG M S SA GL V
Sbjct: 443 QHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPV 502
Query: 353 PHPYESRHVVVHPSPSDYS 371
P + S + HP+P S
Sbjct: 503 PDSFPSGPPLQHPAPDHQS 521
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 61.6 bits (148), Expect = 3e-09
Identities = 60/196 (30%), Positives = 81/196 (41%), Gaps = 46/196 (23%)
Query: 88 SPPSAPRS-------VPVATTLPAAYATPQPGTPVSP-----VQYAHLPHTFQFIGSSQY 135
SP + P S V AT+LP+ +TP P S VQ P+
Sbjct: 373 SPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQ--------- 423
Query: 136 SGTYASFIPSQLIPPTANPVT---SAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPG 192
+ P Q P N +AV A A+ P + S+ ++ L Q
Sbjct: 424 -----AHTPGQAPPRPGNGYLLNPAAVTVAGSASGP-----VAVPSSDMSPAEQLKQMAA 473
Query: 193 HKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISS 252
+ ++ + QQ+QQQQ Q QQQQQQQQQQQQQQH ++ +P PP S
Sbjct: 474 QQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNW-SPLGPP-----------S 521
Query: 253 SPQNTGRTASPPAIPV 268
SP TA P P+
Sbjct: 522 SPYGAAFTAEKPNSPM 537
Score = 49.3 bits (116), Expect = 1e-05
Identities = 99/399 (24%), Positives = 145/399 (36%), Gaps = 56/399 (14%)
Query: 110 QPGTPVSPVQYAHLPHTFQF---IGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGAT 166
Q G P+ YA LP Q +G + +G S +P P + + S + A
Sbjct: 671 QKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVP-----PGSGGMVSGASPAGPGF 725
Query: 167 TPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQH 226
SQ L+ L EQQ+QQ ++Q+Q Q QQQQ +QQ QQ H
Sbjct: 726 LGSQPQAAIMKQMLIDQRAQL-------IEQQKQQFLREQRQQQQQQQQILAEQQLQQSH 778
Query: 227 LSRAPGLITPGSPPPAQQ-NQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHT--LTL 283
L R L +P P QQ NQ+ SPQ+ S A+ + + M + + +
Sbjct: 779 LPR-QHLQPQRNPYPVQQVNQF---QGSPQDIAAVRSQAALQ-SMRTSRLMAQNAGMMGI 833
Query: 284 GP---PSQVVMQYADSGSHFVPREATKKAE------SSRLQQAIQAKEVLNGEMEKSRRY 334
GP P + A S P T ++ S+ + Q +Q + ++
Sbjct: 834 GPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQ 893
Query: 335 GAPSSAD-LGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAA 393
G A G+G G S HP + P G LP P
Sbjct: 894 GPRQPASGQGVGMVSGFGQSMLVNSAITQQHP-----QMKGPVG-----QALPRPQAPPR 943
Query: 394 DLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATA- 452
L+ T ++ + S + L G PG S L P + AS PL G P
Sbjct: 944 -LQSLMGTVQQGAQSW--QQRSLQ-GMPGRTSGELGPF-----NNGASYPLQAGQPRLTK 994
Query: 453 --FYAGTQPPVIGYLSGQQQAITYAGSLPQHL-VIPGTQ 488
F G V+ +G + + A Q + +PG Q
Sbjct: 995 QHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQ 1033
Score = 44.7 bits (104), Expect = 4e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 2/115 (1%)
Query: 164 GATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQ 223
G T P + + + + ++ P QQQQQQQQQQQQ Q QQQ Q Q
Sbjct: 596 GNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAP 655
Query: 224 QQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIP 278
+ HLS + NQ + ++ P + G+ P +P P Q+ +P
Sbjct: 656 RAHLSEDQKRLLL-MKQKGVMNQPMAYAALPSH-GQEQHPVGLPRTTGPMQSSVP 708
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 59.7 bits (143), Expect = 1e-08
Identities = 33/63 (52%), Positives = 36/63 (57%), Gaps = 5/63 (7%)
Query: 193 HKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISS 252
H+ QQQQQQQQQQQ Q QQQQQQQQQQQQQ H L+ A QY H +
Sbjct: 455 HRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLL-----QDAYMQQYQHATQ 509
Query: 253 SPQ 255
Q
Sbjct: 510 QQQ 512
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/147 (27%), Positives = 54/147 (36%), Gaps = 20/147 (13%)
Query: 83 TGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASF 142
T +P P++ T P+ TPV + G + +
Sbjct: 364 TETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLA----------------PGEFGNH 407
Query: 143 IPSQLIPPTANPVTSAVASAAGATTPSQR---SQLEAYSTLLANMGSLSQTPGHKAEQQQ 199
P + P P + P Q QL+ L + + P + +QQQ
Sbjct: 408 RPKGALRPGNGPEI-LLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQ 466
Query: 200 QQQQQQQQQHQHQQQQQQQQQQQQQQH 226
QQQQQQQQQ Q QQQQQQQQ H
Sbjct: 467 QQQQQQQQQQQQQQQQQQQQHHHHHHH 493
Score = 41.6 bits (96), Expect = 0.003
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 8/67 (11%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQ--------QQQQQQQQQQQHLSRAPGLITPGSPP 240
Q + +QQQQQQQQQQQQH H QQ Q QQQ + + L+ P
Sbjct: 467 QQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQP 526
Query: 241 PAQQNQY 247
+QY
Sbjct: 527 QPSASQY 533
Score = 41.2 bits (95), Expect = 0.004
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 20/124 (16%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYV 248
Q + +QQQQQQQQQQ H H Q QQ QH ++ ++ QQ +
Sbjct: 469 QQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQML--------QQQFLM 520
Query: 249 HISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKK 308
H PQ + + TM+P Q++ Q+ S P T
Sbjct: 521 HSVYQPQPSA------------SQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSP 568
Query: 309 AESS 312
E S
Sbjct: 569 QEFS 572
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 59.7 bits (143), Expect = 1e-08
Identities = 33/63 (52%), Positives = 36/63 (57%), Gaps = 5/63 (7%)
Query: 193 HKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISS 252
H+ QQQQQQQQQQQ Q QQQQQQQQQQQQQ H L+ A QY H +
Sbjct: 455 HRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLL-----QDAYMQQYQHATQ 509
Query: 253 SPQ 255
Q
Sbjct: 510 QQQ 512
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/147 (27%), Positives = 54/147 (36%), Gaps = 20/147 (13%)
Query: 83 TGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASF 142
T +P P++ T P+ TPV + G + +
Sbjct: 364 TETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLA----------------PGEFGNH 407
Query: 143 IPSQLIPPTANPVTSAVASAAGATTPSQR---SQLEAYSTLLANMGSLSQTPGHKAEQQQ 199
P + P P + P Q QL+ L + + P + +QQQ
Sbjct: 408 RPKGALRPGNGPEI-LLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQ 466
Query: 200 QQQQQQQQQHQHQQQQQQQQQQQQQQH 226
QQQQQQQQQ Q QQQQQQQQ H
Sbjct: 467 QQQQQQQQQQQQQQQQQQQQHHHHHHH 493
Score = 41.6 bits (96), Expect = 0.003
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 8/67 (11%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQ--------QQQQQQQQQQQHLSRAPGLITPGSPP 240
Q + +QQQQQQQQQQQQH H QQ Q QQQ + + L+ P
Sbjct: 467 QQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQP 526
Query: 241 PAQQNQY 247
+QY
Sbjct: 527 QPSASQY 533
Score = 41.2 bits (95), Expect = 0.004
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 20/124 (16%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYV 248
Q + +QQQQQQQQQQ H H Q QQ QH ++ ++ QQ +
Sbjct: 469 QQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQML--------QQQFLM 520
Query: 249 HISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKK 308
H PQ + + TM+P Q++ Q+ S P T
Sbjct: 521 HSVYQPQPSA------------SQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSP 568
Query: 309 AESS 312
E S
Sbjct: 569 QEFS 572
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/57 (59%), Positives = 38/57 (66%), Gaps = 6/57 (10%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT---PGSPPPA 242
++ QQQQQQQQQQQQ QQQQQQQQQQQQQQ ++ A G T PGSP A
Sbjct: 1594 ESTARNLNQQQQQQQQQQQQ---QQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1647
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/57 (59%), Positives = 38/57 (66%), Gaps = 6/57 (10%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT---PGSPPPA 242
++ QQQQQQQQQQQQ QQQQQQQQQQQQQQ ++ A G T PGSP A
Sbjct: 1742 ESTARNLNQQQQQQQQQQQQ---QQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1795
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/57 (59%), Positives = 38/57 (66%), Gaps = 6/57 (10%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT---PGSPPPA 242
++ QQQQQQQQQQQQ QQQQQQQQQQQQQQ ++ A G T PGSP A
Sbjct: 1742 ESTARNLNQQQQQQQQQQQQ---QQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSA 1795
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 59.3 bits (142), Expect = 1e-08
Identities = 72/266 (27%), Positives = 102/266 (38%), Gaps = 47/266 (17%)
Query: 90 PSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIP 149
P P+ + A L +A A PG P + Q +P F + Q G L
Sbjct: 90 PVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIP----FNMAGQLGGQQGLV----LTL 141
Query: 150 PTANPVTS---AVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQ 206
PTAN A+AAG L+A S+L + + L + + QQQQQQQQQ
Sbjct: 142 PTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQL------QLQLQQQQQQQQQ 195
Query: 207 Q----QHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQ------------------ 244
Q +QH Q Q Q QQQ L P P PPPA Q
Sbjct: 196 QPPPSTNQHPQPAPQAPSQSQQQPLQPTP----PQQPPPASQQPPAPTSQLQQAPQPQQH 251
Query: 245 --NQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVP 302
+ + + P T +++SPP P H +P LT P Q+V S +
Sbjct: 252 QPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHG--LPSPLTPPNPLQLVNNPLASQAAAAA 309
Query: 303 REATKKAESSRLQQAIQAKEVLNGEM 328
+ A S A+ + + + G++
Sbjct: 310 AAMSSIASSQAFGNALSSLQGVTGQL 335
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 57.4 bits (137), Expect = 5e-08
Identities = 38/81 (46%), Positives = 43/81 (53%), Gaps = 6/81 (7%)
Query: 170 QRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSR 229
Q+ QL+ L L Q + QQQQQQQ QQQQ Q QQQQQQQQQQ QQQ +
Sbjct: 3916 QQQQLQQQQQL--QQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQ 3973
Query: 230 APGLITPG----SPPPAQQNQ 246
GL+ SP QQ Q
Sbjct: 3974 QMGLLNQSRTLLSPQQQQQQQ 3994
Score = 52.4 bits (124), Expect = 2e-06
Identities = 28/42 (66%), Positives = 29/42 (69%)
Query: 184 MGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
MGSL Q + QQQQQ QQQQQQ QQQQ QQQQ QQQQ
Sbjct: 3894 MGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Score = 47.8 bits (112), Expect = 4e-05
Identities = 38/117 (32%), Positives = 51/117 (43%), Gaps = 3/117 (2%)
Query: 183 NMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPA 242
N+ S P + Q++Q Q QQQ+ Q+ QQQQQQQQQQQHL + P
Sbjct: 3703 NLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPG 3762
Query: 243 QQNQYVHISSSPQNTGRTASPPAIPV-HLHPHQTMIPHTLTLGPPSQVVMQYADSGS 298
Q + PQ +S + V L P P + LGP V+Q G+
Sbjct: 3763 VQTNQA-LGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGM-LGPAQVAVLQQQHPGA 3817
Score = 47.8 bits (112), Expect = 4e-05
Identities = 26/45 (57%), Positives = 28/45 (62%)
Query: 181 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
L L Q + +QQQQ QQQQQ Q Q QQQQQQQQ QQQQ
Sbjct: 3900 LQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQ 3944
Score = 47.4 bits (111), Expect = 5e-05
Identities = 25/38 (65%), Positives = 27/38 (71%)
Query: 188 SQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
+Q G + QQQQQ QQQQQ Q QQQQQ QQQQQ QQ
Sbjct: 3891 AQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQ 3928
Score = 47.0 bits (110), Expect = 7e-05
Identities = 27/49 (55%), Positives = 32/49 (65%), Gaps = 2/49 (4%)
Query: 179 TLLANMGS--LSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
+L+++ G LS P +Q QQQQQ QQQQ QQQQQQ QQQQQ Q
Sbjct: 3879 SLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQ 3927
Score = 47.0 bits (110), Expect = 7e-05
Identities = 27/46 (58%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 181 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQ-QQQQQQQQQQQ 225
L L Q + +QQQQ QQQQ QQ Q QQQ QQQQQQQ QQQ
Sbjct: 3906 LQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ 3951
Score = 44.7 bits (104), Expect = 4e-04
Identities = 73/287 (25%), Positives = 95/287 (33%), Gaps = 71/287 (24%)
Query: 12 LPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRH----------- 60
L P++R PA S A LP +VE GGRH
Sbjct: 3094 LGPEERPPPAADASEPRLASVLPEVKPKVEE--------------GGRHPSPCQFTIATP 3139
Query: 61 ----GPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVS 116
PA S+ LGL+ G + + T + P S+ + A P
Sbjct: 3140 KVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPP------- 3192
Query: 117 PVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEA 176
AHL + S SG S + + + +A+G S L A
Sbjct: 3193 ----AHL------LTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVA 3242
Query: 177 YSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITP 236
L L H+ ++ Q++QQ Q QQQQQQQQQ L APG
Sbjct: 3243 SELPLLIEDLLE----HEKKELQKKQQLSAQLQPAQQQQQQQQQHS----LLSAPG---- 3290
Query: 237 GSPPPAQQNQYVHISSSPQNTGRT---------ASPPAIPVHLHPHQ 274
PAQ H SSP G A P +P L P Q
Sbjct: 3291 ----PAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQ 3333
Score = 44.7 bits (104), Expect = 4e-04
Identities = 49/197 (24%), Positives = 71/197 (36%), Gaps = 14/197 (7%)
Query: 170 QRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSR 229
Q+ Q + L L Q + +Q QQQQQQQQ +Q + QQQQQQ ++
Sbjct: 3938 QQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVAL 3997
Query: 230 APGLITPGSP-----PPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQ------TMIP 278
PG+ P P P + ++ QNT A HQ P
Sbjct: 3998 GPGM--PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTP 4055
Query: 279 HTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPS 338
++ P DS V + + S +LQ ++ ++ G S
Sbjct: 4056 ESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS 4115
Query: 339 SADLGLGKAG-GKSVPH 354
LG G + SVPH
Sbjct: 4116 HGQLGSGSSSEASSVPH 4132
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/88 (36%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Query: 170 QRSQLEAYSTLLANMGSLSQTPGHKAEQQQ--QQQQQQQQQHQHQQQQQQQQQQQQQQHL 227
Q+ + S L ++ S S P A+ QQ QQQQQ Q QQ QQQQQQQ QQQ
Sbjct: 3866 QQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQ 3925
Query: 228 SRAPGLITPGSPPPAQQNQYVHISSSPQ 255
+ L QQ Q + Q
Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQLQQQQQ 3953
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 24/80 (30%)
Query: 182 ANMGSLSQTPGHKAEQQQQQQQQQQQQHQH----------QQQQQQQQQQQQQQH----- 226
A+ L +++ Q+Q Q ++QQ +H QQQQQQQQQQQQQQH
Sbjct: 3559 ADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLA 3618
Query: 227 ---------LSRAPGLITPG 237
L++ PG + PG
Sbjct: 3619 LSPSQSPRLLTKLPGQLLPG 3638
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/161 (29%), Positives = 64/161 (39%), Gaps = 28/161 (17%)
Query: 181 LANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQ--------QQQQQHLSRAPG 232
L ++G S+ + Q QQQ+ Q Q+ Q QQQQQQQQQ QQQQQ + PG
Sbjct: 3706 LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQ---QGPG 3762
Query: 233 LITPGS---------PPPAQQNQYVHISS--SPQNTGRTASPPAIPVHLHPHQTMI---- 277
+ T + PP + Q V S PQ P + V H +
Sbjct: 3763 VQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQG 3822
Query: 278 PHTLTLGPPSQVVM--QYADSGSHFVPREATKKAESSRLQQ 316
PH L S+V+ Q A G + + + QQ
Sbjct: 3823 PHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQ 3863
Score = 40.0 bits (92), Expect = 0.009
Identities = 23/53 (43%), Positives = 32/53 (60%), Gaps = 7/53 (13%)
Query: 194 KAEQQQQQQQQQQQQH-------QHQQQQQQQQQQQQQQHLSRAPGLITPGSP 239
K ++Q Q ++QQ++H +++QQQQQQQQQQQQQ S L SP
Sbjct: 3573 KIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSP 3625
Score = 34.3 bits (77), Expect = 0.48
Identities = 29/91 (31%), Positives = 31/91 (34%), Gaps = 36/91 (39%)
Query: 192 GHKAEQQQQQQQQQQQ------------------------------------QHQHQQQQ 215
GH+ QQQQQQQQ Q Q Q QQ
Sbjct: 3849 GHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQ 3908
Query: 216 QQQQQQQQQQHLSRAPGLITPGSPPPAQQNQ 246
QQQ QQQQQQ L + L QQ Q
Sbjct: 3909 QQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQ 3939
Score = 30.4 bits (67), Expect = 6.9
Identities = 36/165 (21%), Positives = 66/165 (40%), Gaps = 34/165 (20%)
Query: 90 PSAPRSVPVATTLPAAYATPQP-GTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLI 148
P P +T A P G+P+ P GS+ S + P ++
Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSS-----------GSTGESYGLSPLRPPSVL 2616
Query: 149 PPTANP-----VTSAVASAAGATTPSQRSQ------------LEAYSTLLANMGSLSQTP 191
PP A ++ + +G T+P ++ + E T M LSQT
Sbjct: 2617 PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQT- 2675
Query: 192 GHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITP 236
E ++Q+Q+Q+ ++ +QQ Q+ +Q+++ + A G + P
Sbjct: 2676 ----ELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGP 2716
>gi|40354197 THAP domain containing 11 [Homo sapiens]
Length = 314
Score = 57.0 bits (136), Expect = 7e-08
Identities = 28/44 (63%), Positives = 32/44 (72%)
Query: 192 GHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT 235
G A +++QQQQQQQQQ Q QQQQQQQQQQQQQQ +P T
Sbjct: 96 GAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSAST 139
Score = 53.9 bits (128), Expect = 6e-07
Identities = 26/43 (60%), Positives = 32/43 (74%)
Query: 183 NMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQ 225
N +++ P A +++QQQQQQQQ Q QQQQQQQQQQQQQQ
Sbjct: 86 NERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQ 128
Score = 53.1 bits (126), Expect = 1e-06
Identities = 26/35 (74%), Positives = 27/35 (77%)
Query: 196 EQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRA 230
+QQQQQQQQQQQQ Q QQQQQQQQQQQ S A
Sbjct: 106 QQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTA 140
Score = 50.1 bits (118), Expect = 8e-06
Identities = 24/37 (64%), Positives = 28/37 (75%)
Query: 185 GSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQ 221
G+ + + +QQQQQQQQQQQQ Q QQQQQQQQQQ
Sbjct: 96 GAAAARRRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 132
Score = 44.3 bits (103), Expect = 5e-04
Identities = 22/47 (46%), Positives = 26/47 (55%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLIT 235
Q + +QQQQQQQQQQQQ Q QQQQQ Q P L++
Sbjct: 105 QQQQQQQQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVS 151
Score = 36.2 bits (82), Expect = 0.13
Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 189 QTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLI------------TP 236
Q + +QQQQQQQQQQQQ Q Q Q Q +L A + P
Sbjct: 111 QQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASAAVLLTLQATVDSSQAP 170
Query: 237 GSPPPA 242
GS PA
Sbjct: 171 GSVQPA 176
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/130 (35%), Positives = 57/130 (43%), Gaps = 34/130 (26%)
Query: 147 LIPPTANPVTSAVASAAGAT----TPSQRSQLEAYSTLLANM---------GSLSQTPGH 193
+IPP N +S +A TP SQ +A LL+ + GSL+ P H
Sbjct: 183 MIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAP-PHH 241
Query: 194 --------------------KAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGL 233
+ +QQQQQQQQQQQQ Q QQQQQQ Q + QQH + P
Sbjct: 242 PMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQG 301
Query: 234 ITPGSPPPAQ 243
I P P Q
Sbjct: 302 IRPQFTAPTQ 311
Score = 54.7 bits (130), Expect = 3e-07
Identities = 61/216 (28%), Positives = 79/216 (36%), Gaps = 44/216 (20%)
Query: 182 ANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPG---- 237
AN L Q + +QQQQQQQQQQQQ Q Q Q + QQ QQQQ P P
Sbjct: 255 ANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPV 314
Query: 238 ------------SPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGP 285
PPPAQ + + + N G +P +P + P T+
Sbjct: 315 PPGWNQLPSGALQPPPAQGS----LGTMTANQGWKKAP--LPGPMQQQLQARPSLATVQT 368
Query: 286 PSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLG 345
PS Y QQA QA +M ++ AP L
Sbjct: 369 PSHPPPPYPFGS-----------------QQASQAHTNF-PQMSNPGQFTAPQMKSL--- 407
Query: 346 KAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRAS 381
+ G VP P + H + + SP+ S G AS
Sbjct: 408 QGGPSRVPTPLQQPH-LTNKSPASSPSSFQQGSPAS 442
Score = 42.7 bits (99), Expect = 0.001
Identities = 98/438 (22%), Positives = 150/438 (34%), Gaps = 52/438 (11%)
Query: 170 QRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQ------ 223
QR + L+ ++ Q P + + Q QQQQ Q Q QQQQQQQQQ
Sbjct: 980 QRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMM 1039
Query: 224 -----------QQHLSRAPGLITPGSP-PPAQQNQYVHISSSPQNTGRTASPPAIPVHLH 271
Q++ G + P S P QQ+ V + S Q P ++P
Sbjct: 1040 QQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQ------GPASVPPSPD 1093
Query: 272 PHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQA--IQAKEVLNGEME 329
+ +P LG S+ M Y +S + ++ AE + L +A +A V G
Sbjct: 1094 KQRMPMPVNTPLGSNSR-KMVYQESPQN---PSSSPLAEMASLPEASGSEAPSVPGGPNN 1149
Query: 330 KSRRYGAPSSADLGLGKAGGKSVPHPYES------RHVVVHPSPSDYSSRDPSGVRASVM 383
P + L G K P P + + V+ PS + P+ +
Sbjct: 1150 MPSHVVLPQNQ---LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQT 1206
Query: 384 VLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEP 443
P + A+ T PST + L + L P + + P
Sbjct: 1207 SRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQI-------NIP 1259
Query: 444 LP--VGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPL-LIPVGSTDME 500
LP L G P + + QA + P + P T L + V S
Sbjct: 1260 LPPRPNLNRGFDQQGLNPTTLKAIG---QAPSNLTMNPSNFATPQTHKLDSVVVNSGKQS 1316
Query: 501 ASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSV 560
SGA S+ + ++ + TT P +N L + A + + LP V
Sbjct: 1317 NSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLV 1376
Query: 561 ASPAAAPPTLPPYFMKGS 578
+ A P +P F S
Sbjct: 1377 SPTPLANPPVPGSFPNNS 1394
Score = 40.0 bits (92), Expect = 0.009
Identities = 95/491 (19%), Positives = 160/491 (32%), Gaps = 46/491 (9%)
Query: 20 PATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQQGIGLHK 79
P +++ ++ P P +N +G +PG + P V G +
Sbjct: 444 PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG-PQ 502
Query: 80 ALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTY 139
+L GL P P P P T + + P Q + Q++G
Sbjct: 503 SLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQ-LQANQNVQHAGGQ 561
Query: 140 ASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQ 199
+ P + + P S G Q N+ ++ P Q
Sbjct: 562 GAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQL 621
Query: 200 QQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSP---PPAQQNQYVHISSSPQN 256
QQ Q Q QQQ Q + L+ G PP+Q ++ SPQ
Sbjct: 622 MGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ-----NLGPSPQR 676
Query: 257 TGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQ 316
+PP + Q M PH +GP QV++Q + + + T + + ++ Q
Sbjct: 677 M----TPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQ----NPMIEQIMTNQMQGNKQQF 728
Query: 317 AIQ-AKEVLNGEMEKSRRYGAPSSADL--GLGKAGGKSVPHPYESRHVVVHPSPSDYSSR 373
Q V+ G + R ++ G+ G+ +P P + S
Sbjct: 729 NTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLP----------QQGPVNNSPS 778
Query: 374 DPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPG---HRSYALSP 430
G++ V+ P + A AT T N+ L P ++ + P
Sbjct: 779 QVMGIQGQVLRPPGPSPHMAQQHGDPAT-------TANNDVSLSQMMPDVSIQQTNMVPP 831
Query: 431 HTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPL 490
H +SAS G + P G +G Q + P + + T PL
Sbjct: 832 HVQAMQGNSAS-----GNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPL 886
Query: 491 LIPVGSTDMEA 501
L+ + +D+ A
Sbjct: 887 LVNLLQSDISA 897
Score = 38.9 bits (89), Expect = 0.019
Identities = 85/375 (22%), Positives = 134/375 (35%), Gaps = 31/375 (8%)
Query: 188 SQTPGHKAEQQQQQ--QQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQN 245
++ PG+ ++ +Q+ QQ Q QH Q QQQ Q L + P P QQ
Sbjct: 968 NRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQ 1027
Query: 246 QYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQ-VVMQYADSGSHFV--- 301
Q + +PV + H P L P SQ + MQ + S V
Sbjct: 1028 QQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP----LNPDSQRMPMQQSGSVPVMVSLQ 1083
Query: 302 -PREATKKAESSRLQQAIQAKEVLNG-EMEKSRRYGAPSSADLGLGKAGGKSVPHPYESR 359
P + R+ + N +M PSS+ L A S+P S
Sbjct: 1084 GPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPL----AEMASLPEASGSE 1139
Query: 360 HVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLG 419
V P++ S +M P P+ Q AT ++ ++L G H
Sbjct: 1140 APSVPGGPNNMPSHVVLPQNQLMMTGPKPG-PSPLSATQGATPQQPPVNSLPSSHGHHFP 1198
Query: 420 KPGHRSYALSPHTVIQTTHSASEP-LPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSL 478
+ P T + + P P P + T+P I LS ++ + AG
Sbjct: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPS-----TEPSEIS-LSPERLNASIAGLF 1252
Query: 479 PQHLVIP-GTQPLL------IPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSE 531
P + IP +P L + T ++A G AP+ +T +P A P T ++ +
Sbjct: 1253 PPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNS 1312
Query: 532 NFNPEALVTQAAYPA 546
+ T+ A P+
Sbjct: 1313 GKQSNSGATKRASPS 1327
Score = 36.2 bits (82), Expect = 0.13
Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 20/164 (12%)
Query: 301 VPREATKK----AESSR--------LQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAG 348
+PREA ++ A+S+ L I+ + +N + ++R + +G G +
Sbjct: 100 IPREAAERLRILAQSNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSV 159
Query: 349 GKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPS 408
P S ++ + P G +S M+ P N E+Q T R AS S
Sbjct: 160 RMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNP-----ELQPRTPRPASQS 214
Query: 409 TLNDK--SGLHLGKPGHRSYALS-PHTVIQTTHSASEPLPVGLP 449
D SGLH+ + H S +L+ PH +Q + P P
Sbjct: 215 DAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFP 258
Score = 31.2 bits (69), Expect = 4.0
Identities = 68/316 (21%), Positives = 104/316 (32%), Gaps = 59/316 (18%)
Query: 83 TGLDYSPPSAP----RSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGS------ 132
T L+ +PP + V TL ++ +P ++ LPH+ + S
Sbjct: 1511 TDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLN------LPHSNELCSSLVHPEL 1564
Query: 133 SQYSGTYASFIP------------SQLIPP-------TANPVTSAVASAAGATTPSQRSQ 173
S+ S A IP S +PP T+NP+T++ ++A T Q +
Sbjct: 1565 SEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSAL 1624
Query: 174 LEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGL 233
+ T+ + + G A Q + Q + Q + Q + AP
Sbjct: 1625 MSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLT 1684
Query: 234 ITPGSPPPA-------QQNQYVHISSSPQNTGRTASPP---------------AIPVHL- 270
G PP+ Q + SS+P +S P A PV L
Sbjct: 1685 TNSGLMPPSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQLP 1744
Query: 271 HPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEK 330
P T P + P QV D S V A + S Q +L
Sbjct: 1745 SPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSS-QSTTMVSPLLTNSPGS 1803
Query: 331 SRRYGAPSSADLGLGK 346
S +P S+ G GK
Sbjct: 1804 SGNRRSPVSSSKGKGK 1819
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 56.2 bits (134), Expect = 1e-07
Identities = 50/158 (31%), Positives = 58/158 (36%), Gaps = 49/158 (31%)
Query: 198 QQQQQQQQQQQHQHQQQQQQQQQQQQQQHL-----SRAPGLITPGSPPPAQQNQYVHISS 252
QQQ QQQQQQQ Q QQQQQQQQQQQ+ HL + PG PG+ A ++ S
Sbjct: 125 QQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPG---PGAWRSAAAAAHLPPSM 181
Query: 253 SPQNTGRTASPPAIPV----------------------------------HLHPHQTMIP 278
N G S P+ V H HPHQ P
Sbjct: 182 GASNGGLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPP 241
Query: 279 HTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQ 316
GPP G+H P S L+Q
Sbjct: 242 PPPPQGPPGH-------PGAHHDPHSDEDTPTSDDLEQ 272
>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
Length = 609
Score = 56.2 bits (134), Expect = 1e-07
Identities = 86/319 (26%), Positives = 116/319 (36%), Gaps = 45/319 (14%)
Query: 14 PKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGN--PGGRGHGGGRHGPAGTSVELGL 71
P +RE P ++ APT+ G A PG+ P G G AGT V G
Sbjct: 233 PAEREAPDKKKAEAAAAPTV------APGPAQ-PGHVSPTPATTSPGEKGEAGTPVAAGT 285
Query: 72 QQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIG 131
A + ++P PA P ++ LP T Q
Sbjct: 286 T-------AAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRT 338
Query: 132 SSQYSGTYASFIP-----SQLIPPTANPVTSAVASAAGATT--PSQRSQLEAYSTLLANM 184
Q GT P S I ++S+ ASA P + A+
Sbjct: 339 DFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPP 398
Query: 185 GSLSQTPGHKAE--------QQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITP 236
+ Q PGHK ++ Q + QQQ Q QQQQQQQQQQQQQQ S AP P
Sbjct: 399 AAAFQ-PGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMP 457
Query: 237 GS--PPPAQQNQY------VHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLG-PPS 287
+ P PA + V + P + PP +P + +P +G PS
Sbjct: 458 PALQPFPAPVGPFDAAPAQVAVFLPPPH----MQPPFVPAYPGLGYPPMPRVPVVGITPS 513
Query: 288 QVVMQYADSGSHFVPREAT 306
Q+V S + P+ AT
Sbjct: 514 QMVANAFCSAAQLQPQPAT 532
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 55.8 bits (133), Expect = 2e-07
Identities = 79/297 (26%), Positives = 110/297 (37%), Gaps = 59/297 (19%)
Query: 193 HKAEQQQQQQQQQQQ-----QHQHQQQQQQQQQQQQQQHLSRAPGLITPG----SPPPAQ 243
H+ +QQ QQQQQQ Q Q Q QQQQQQQQQQQQQQ L P + P PPP+Q
Sbjct: 225 HQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQ 284
Query: 244 ----QNQYVHISSSPQNTGRTASPPAI---PVHLHPHQTMIP----------HTLTLGPP 286
Q Q +H + Q + PP P L P P L PP
Sbjct: 285 ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344
Query: 287 SQVVMQYADSGSHFVPREATKKAESSRLQQAIQ---------AKEVLNGEMEKSRRY--- 334
+ V V + ++ + + QA Q + + G M R+
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT 404
Query: 335 ---GAPSSADLGLGK-----AGGKSVP---HPYESRHVVV----------HPSPSDYSSR 373
A S+ + LG+ S+P P + V P P SS+
Sbjct: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 464
Query: 374 DPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSP 430
S V + P+S P+ + Q+ +P + S L P + S +SP
Sbjct: 465 PNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSP 521
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/65 (52%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 193 HKAEQQQQQQQQQQQQH--QHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHI 250
H QQQ QQQQQQ Q Q Q QQQQQQQQQQQQ +A P PP QQ Q
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPS 283
Query: 251 SSSPQ 255
+ PQ
Sbjct: 284 QALPQ 288
Score = 52.8 bits (125), Expect = 1e-06
Identities = 93/427 (21%), Positives = 142/427 (33%), Gaps = 111/427 (25%)
Query: 154 PVTSAVA--SAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQH 211
P TS +A S A +T + ++QL+ L QQQQQQQQ QQQ Q
Sbjct: 131 PGTSGMAPHSMAVVSTATPQTQLQLQQVAL---------------QQQQQQQQFQQQQQA 175
Query: 212 QQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLH 271
QQQQQQQQQQQ ++ A Q Q+ + Q L
Sbjct: 176 ALQQQQQQQQQQQFQAQQS-----------AMQQQFQAVVQQQQ-------------QLQ 211
Query: 272 PHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGE---M 328
Q H + L +Q +Q + + ++ + + QQ Q ++ L +
Sbjct: 212 QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ 271
Query: 329 EKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNS 388
+ + P + +++P + H H P + P + P S
Sbjct: 272 QPPMQQPQPPPS---------QALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQS 322
Query: 389 NTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGL 448
T + Q PG Y P ++ P+ V
Sbjct: 323 QTQPLVSQAQ--------------------ALPGQMLYTQPPLKFVRA------PMVV-- 354
Query: 449 PATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAI 508
QPPV + QQ A+ A + +V PG Q + + M
Sbjct: 355 --------QQPPVQPQVQQQQTAVQTAQA--AQMVAPGVQMITEALAQGGMHIR------ 398
Query: 509 VTSSPQFAAVPHTFVTTALPKSE---NFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAA 565
A P T +A+P S P A V+Q++ P + Q V +P +
Sbjct: 399 -------ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPS----PGQQVQTPQS 447
Query: 566 APPTLPP 572
PP P
Sbjct: 448 MPPPPQP 454
Score = 51.2 bits (121), Expect = 4e-06
Identities = 35/91 (38%), Positives = 41/91 (45%), Gaps = 12/91 (13%)
Query: 149 PPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQ- 207
PP + + + TP + QL+ + Q A QQQQQQQQQQQ
Sbjct: 130 PPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQF 189
Query: 208 -----------QHQHQQQQQQQQQQQQQQHL 227
Q QQQQQ QQQQQQQQHL
Sbjct: 190 QAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL 220
Score = 30.4 bits (67), Expect = 6.9
Identities = 42/185 (22%), Positives = 78/185 (42%), Gaps = 29/185 (15%)
Query: 93 PRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTA 152
P+S+P P +PQPG P S P++ SS + + +SF+PS P+
Sbjct: 445 PQSMP-----PPPQPSPQPGQPSSQ------PNSNV---SSGPAPSPSSFLPSPSPQPSQ 490
Query: 153 NPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQ 212
+PVT+ +P + S++++ GS +AE+QQ + +Q +
Sbjct: 491 SPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS------SQAEEQQYLDKLKQLSKYIE 544
Query: 213 QQQQQ----QQQQQQQQHLSRAPGLI----TPGSPPPAQQNQYVHIS-SSPQNTGRTASP 263
++ + + +++ LS+ L+ P P + Q I+ +N +P
Sbjct: 545 PLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTP 604
Query: 264 PAIPV 268
P PV
Sbjct: 605 PPPPV 609
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,433,772
Number of Sequences: 37866
Number of extensions: 2080322
Number of successful extensions: 27633
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 465
Number of HSP's that attempted gapping in prelim test: 12883
Number of HSP's gapped (non-prelim): 6087
length of query: 815
length of database: 18,247,518
effective HSP length: 111
effective length of query: 704
effective length of database: 14,044,392
effective search space: 9887251968
effective search space used: 9887251968
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.