Guide to the Human Genome
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Search of human proteins with 51173737

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51173737 ras responsive element binding protein 1 isoform 1
[Homo sapiens]
         (1742 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51173737 ras responsive element binding protein 1 isoform 1 [...  3548   0.0  
gi|51173735 ras responsive element binding protein 1 isoform 2 [...  3388   0.0  
gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor...   111   7e-24
gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor...   111   7e-24
gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor...   111   7e-24
gi|188497655 zinc finger protein 84 [Homo sapiens]                    111   7e-24
gi|188497653 zinc finger protein 84 [Homo sapiens]                    111   7e-24
gi|190610025 zinc finger protein 93 homolog [Homo sapiens]            110   9e-24
gi|122937229 zinc finger protein 629 [Homo sapiens]                   110   9e-24
gi|134254457 zinc finger protein 665 [Homo sapiens]                   108   6e-23
gi|206725458 zinc finger protein 561 [Homo sapiens]                   106   2e-22
gi|37537684 zinc finger protein 92 isoform 1 [Homo sapiens]           106   2e-22
gi|55741868 zinc finger protein 319 [Homo sapiens]                    106   2e-22
gi|23097323 zinc finger protein 92 isoform 2 [Homo sapiens]           106   2e-22
gi|14211907 zinc finger protein 347 [Homo sapiens]                    105   4e-22
gi|155722996 zinc finger protein 544 [Homo sapiens]                   105   4e-22
gi|154091003 zinc finger protein 470 [Homo sapiens]                   105   5e-22
gi|157412267 zinc finger protein 221 [Homo sapiens]                   105   5e-22
gi|157952211 zinc finger protein 250 isoform b [Homo sapiens]         104   9e-22
gi|45387947 zinc finger protein 250 isoform a [Homo sapiens]          104   9e-22
gi|194018469 zinc finger protein 546 [Homo sapiens]                   104   9e-22
gi|156766086 zinc finger protein 600 [Homo sapiens]                   104   9e-22
gi|38708324 zinc finger protein 93 [Homo sapiens]                     103   1e-21
gi|153791560 zinc finger protein 799 [Homo sapiens]                   103   1e-21
gi|23308729 zinc finger protein 268 [Homo sapiens]                    103   1e-21
gi|28274682 zinc finger protein 33A isoform b [Homo sapiens]          103   1e-21
gi|110347446 zinc finger protein 33A isoform a [Homo sapiens]         103   1e-21
gi|23308737 zinc finger protein 23 [Homo sapiens]                     102   2e-21
gi|52138523 zinc finger protein 418 [Homo sapiens]                    102   2e-21
gi|116875834 zinc finger protein 74 [Homo sapiens]                    102   2e-21

>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1742

 Score = 3548 bits (9200), Expect = 0.0
 Identities = 1742/1742 (100%), Positives = 1742/1742 (100%)

Query: 1    MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETK 60
            MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETK
Sbjct: 1    MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETK 60

Query: 61   EEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHS 120
            EEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHS
Sbjct: 61   EEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHS 120

Query: 121  GERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES 180
            GERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES
Sbjct: 121  GERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES 180

Query: 181  EREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDIC 240
            EREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDIC
Sbjct: 181  EREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDIC 240

Query: 241  CVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA 300
            CVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA
Sbjct: 241  CVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA 300

Query: 301  WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ 360
            WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ
Sbjct: 301  WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ 360

Query: 361  KGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASL 420
            KGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASL
Sbjct: 361  KGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASL 420

Query: 421  GGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASA 480
            GGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASA
Sbjct: 421  GGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASA 480

Query: 481  PPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISP 540
            PPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISP
Sbjct: 481  PPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISP 540

Query: 541  SLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDS 600
            SLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDS
Sbjct: 541  SLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDS 600

Query: 601  IIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRA 660
            IIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRA
Sbjct: 601  IIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRA 660

Query: 661  HVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRK 720
            HVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRK
Sbjct: 661  HVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRK 720

Query: 721  KHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGL 780
            KHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGL
Sbjct: 721  KHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGL 780

Query: 781  GGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAE 840
            GGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAE
Sbjct: 781  GGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAE 840

Query: 841  ASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPL 900
            ASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPL
Sbjct: 841  ASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPL 900

Query: 901  DFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPE 960
            DFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPE
Sbjct: 901  DFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPE 960

Query: 961  EEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYS 1020
            EEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYS
Sbjct: 961  EEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYS 1020

Query: 1021 SALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPT 1080
            SALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPT
Sbjct: 1021 SALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPT 1080

Query: 1081 LLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAAS 1140
            LLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAAS
Sbjct: 1081 LLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAAS 1140

Query: 1141 PTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTA 1200
            PTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTA
Sbjct: 1141 PTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTA 1200

Query: 1201 EDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASS 1260
            EDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASS
Sbjct: 1201 EDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASS 1260

Query: 1261 LQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPQSKESDVGS 1320
            LQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPQSKESDVGS
Sbjct: 1261 LQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPQSKESDVGS 1320

Query: 1321 HDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHRE 1380
            HDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHRE
Sbjct: 1321 HDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHRE 1380

Query: 1381 EHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGG 1440
            EHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGG
Sbjct: 1381 EHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGG 1440

Query: 1441 AASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKP 1500
            AASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKP
Sbjct: 1441 AASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKP 1500

Query: 1501 PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVAS 1560
            PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVAS
Sbjct: 1501 PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVAS 1560

Query: 1561 KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKA 1620
            KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKA
Sbjct: 1561 KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKA 1620

Query: 1621 RHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASA 1680
            RHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASA
Sbjct: 1621 RHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASA 1680

Query: 1681 TKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVG 1740
            TKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVG
Sbjct: 1681 TKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVG 1740

Query: 1741 ME 1742
            ME
Sbjct: 1741 ME 1742


>gi|51173735 ras responsive element binding protein 1 isoform 2 [Homo
            sapiens]
          Length = 1687

 Score = 3388 bits (8785), Expect = 0.0
 Identities = 1679/1742 (96%), Positives = 1684/1742 (96%), Gaps = 55/1742 (3%)

Query: 1    MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETK 60
            MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETK
Sbjct: 1    MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETK 60

Query: 61   EEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHS 120
            EEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHS
Sbjct: 61   EEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHS 120

Query: 121  GERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES 180
            GERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES
Sbjct: 121  GERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES 180

Query: 181  EREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDIC 240
            EREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDIC
Sbjct: 181  EREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDIC 240

Query: 241  CVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA 300
            CVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA
Sbjct: 241  CVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA 300

Query: 301  WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ 360
            WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ
Sbjct: 301  WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ 360

Query: 361  KGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASL 420
            KGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASL
Sbjct: 361  KGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASL 420

Query: 421  GGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASA 480
            GGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASA
Sbjct: 421  GGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASA 480

Query: 481  PPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISP 540
            PPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISP
Sbjct: 481  PPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISP 540

Query: 541  SLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDS 600
            SLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDS
Sbjct: 541  SLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDS 600

Query: 601  IIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRA 660
            IIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRA
Sbjct: 601  IIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRA 660

Query: 661  HVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRK 720
            HVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRK
Sbjct: 661  HVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRK 720

Query: 721  KHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGL 780
            KHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGL
Sbjct: 721  KHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGL 780

Query: 781  GGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAE 840
            GGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAE
Sbjct: 781  GGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAE 840

Query: 841  ASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPL 900
            ASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPL
Sbjct: 841  ASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPL 900

Query: 901  DFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPE 960
            DFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPE
Sbjct: 901  DFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPE 960

Query: 961  EEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYS 1020
            EEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYS
Sbjct: 961  EEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYS 1020

Query: 1021 SALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPT 1080
            SALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPT
Sbjct: 1021 SALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPT 1080

Query: 1081 LLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAAS 1140
            LLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAAS
Sbjct: 1081 LLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAAS 1140

Query: 1141 PTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTA 1200
            PTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTA
Sbjct: 1141 PTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTA 1200

Query: 1201 EDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASS 1260
            EDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASS
Sbjct: 1201 EDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASS 1260

Query: 1261 LQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPQSKESDVGS 1320
            LQRHMLTHT  +                                                
Sbjct: 1261 LQRHMLTHTDSQ------------------------------------------------ 1272

Query: 1321 HDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHRE 1380
               +D+++ A    AAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHRE
Sbjct: 1273 ---SDAETAA----AAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHRE 1325

Query: 1381 EHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGG 1440
            EHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGG
Sbjct: 1326 EHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGG 1385

Query: 1441 AASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKP 1500
            AASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKP
Sbjct: 1386 AASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKP 1445

Query: 1501 PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVAS 1560
            PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVAS
Sbjct: 1446 PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVAS 1505

Query: 1561 KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKA 1620
            KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKA
Sbjct: 1506 KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKA 1565

Query: 1621 RHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASA 1680
            RHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASA
Sbjct: 1566 RHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASA 1625

Query: 1681 TKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVG 1740
            TKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVG
Sbjct: 1626 TKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVG 1685

Query: 1741 ME 1742
            ME
Sbjct: 1686 ME 1687


>gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2
            [Homo sapiens]
          Length = 738

 Score =  111 bits (277), Expect = 7e-24
 Identities = 94/373 (25%), Positives = 138/373 (36%), Gaps = 19/373 (5%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L  H  THTG+KP+ C +C   FS KSN   HQ    G      R  
Sbjct: 293  CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G     K   V  H +         +       + +   R Q            G+ P E
Sbjct: 353  GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH--------TGEKPYE 404

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---DLDFATKL 1424
             +    A            +H  E+ HG  +  G A   +    S+Q     +  F    
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQC-GKAFSQKSHLISHQMTHTGEKPFICSK 463

Query: 1425 MDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGAS 1484
                 +            + E+   C  CGK+F    +L+ H++ H  ++P      G +
Sbjct: 464  CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523

Query: 1485 TAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKS 1544
              ++       Q     E P E  E     GE  +    + T     GE   E R  EK+
Sbjct: 524  FCQKS-HLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTH---TGEKPYECRDCEKA 579

Query: 1545 DDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTF 1604
               K       +       ++   CS+C K F+   +L RH+R+HTGE+PY+C  C + F
Sbjct: 580  FSQKSQLNTHQRI---HTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAF 636

Query: 1605 TLKHSLVRHQRIH 1617
              K SL+ HQRIH
Sbjct: 637  REKSSLINHQRIH 649



 Score =  106 bits (265), Expect = 2e-22
 Identities = 79/314 (25%), Positives = 132/314 (42%), Gaps = 10/314 (3%)

Query: 31  TENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNT 90
           T  G  P G     K          +Q T   +  + C  C K  + + QL  H R H  
Sbjct: 424 THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTH-- 481

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
            TG   + CS CGK+ S   SL  H  +H+GE+PY C+ CG++F    ++  H + H  +
Sbjct: 482 -TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGE 540

Query: 151 PNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVF 208
                +    +  ++  L++ ++ +H  E   E     K   +  Q    ++    ++ +
Sbjct: 541 KPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 209 HCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM- 266
            C +C K F  K  L  H+ TH+ + P  C+ C   FR    L+ H  +   + P +   
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 267 -GRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKA 324
            G+ F + +  IP      G   + C +  +  SQ     N +R  + +  + C  C KA
Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719

Query: 325 FPMLCSLALHKQTH 338
           F     L  H++TH
Sbjct: 720 FSQKSQLINHQRTH 733



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 84/317 (26%), Positives = 122/317 (38%), Gaps = 21/317 (6%)

Query: 65  SYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP 124
           ++ C  C K    + Q   H   H T TG   ++CS CGK+ S  S L  H   H+GE+P
Sbjct: 234 AFGCGNCGKTFPQKSQFITH---HRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKP 290

Query: 125 YKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           Y+C  CG++F+   ++  H + H  +          +  ++  L + +++ H  E   E 
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRI-HTGEKPFEC 349

Query: 185 PAPAKKMVEDGQ--SGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
               K      Q  +        + F C  C K F  K  L  H   H+ + P  C  C 
Sbjct: 350 RECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECR 409

Query: 242 VTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSCRK----FP 295
             FR    L+ H      + P   +  G+ F Q +  I       G   F C K    F 
Sbjct: 410 KAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFS 469

Query: 296 RISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPG 355
           R SQ       +R  + +  + C  C KAF    SL  H++ H       EKP      G
Sbjct: 470 RKSQL---VRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG-----EKPYVCSECG 521

Query: 356 DALDQKGFLALLGLQHT 372
            A  QK  L      HT
Sbjct: 522 KAFCQKSHLISHQRTHT 538



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 81/312 (25%), Positives = 122/312 (39%), Gaps = 37/312 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C K  + +  L  H   H   TG     CS CGK+ S  S L RH
Sbjct: 421 HQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRH 477

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+PY+C+ CG++F+   ++  H +IH  +     +    +  ++  L S ++ +
Sbjct: 478 QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQR-T 536

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKK--ADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           H  E   E     K   E       ++    ++ + C  C K F  K  L TH   H+ +
Sbjct: 537 HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGE 596

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            P  C +C   F     L+RH       L      +P+  N                 CR
Sbjct: 597 KPYECSLCRKAFFEKSELIRH-------LRTHTGEKPYECNE----------------CR 633

Query: 293 KFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATP 352
           K  R   +    N +R  + +  F C  C KAF     L  H++TH       EKP    
Sbjct: 634 KAFREKSSLI--NHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTG-----EKPYGCS 686

Query: 353 LPGDALDQKGFL 364
               A  QK  L
Sbjct: 687 ECRKAFSQKSQL 698



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 57/185 (30%), Positives = 73/185 (39%), Gaps = 45/185 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y CR C + F+    L  H R H G  PY+C++C     +K+ LIRHLRTH+GE+PY C 
Sbjct: 571 YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECN 630

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++   H R   +    K  E                       C  CG+  
Sbjct: 631 ECRKAFREKSSLINHQR---IHTGEKPFE-----------------------CSECGKAF 664

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+ C EC  AF+ K 
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 804 NCIHH 808
             I+H
Sbjct: 725 QLINH 729



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 82/329 (24%), Positives = 127/329 (38%), Gaps = 47/329 (14%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +  T   +  YNC  C K  + + QLT H R H   TG   + C  CGK+ S  S L  H
Sbjct: 253 HHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---TGEKPYECGECGKAFSRKSHLISH 309

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDP---------------------NSA 154
              H+GE+PY C  CG++F+   N+  H +IH  +                       + 
Sbjct: 310 WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTH 369

Query: 155 TATAP--PSPLKRRRLSSKRKLSHDAESEREDP---APAKKMVEDGQSGDLEKKA---DE 206
           T T P   S  ++        + H      E P   +  +K   +  S    ++    ++
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429

Query: 207 VFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA 265
              C  C K F  K  L +H  TH+ + P  C  C   F     L+RH      + P + 
Sbjct: 430 PHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYEC 489

Query: 266 M--GRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNL----RRCISEQHRFVCD 319
              G+ F +            G   + C +     +A+C+ +     +R  + +  + C 
Sbjct: 490 SECGKAFSEKLSLTNHQRIHTGEKPYVCSE---CGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 320 TCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C KAF    SLA H++TH       EKP
Sbjct: 547 ECGKAFGEKSSLATHQRTHTG-----EKP 570



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 59/196 (30%), Positives = 77/196 (39%), Gaps = 48/196 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY+C  C    + K+ LI H RTH+GE+PY C 
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCN 322

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+N   H R   +    K  E                       CR CG+  
Sbjct: 323 ECGRAFSEKSNLINHQR---IHTGEKPFE-----------------------CRECGKAF 356

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+EC EC  AF  + 
Sbjct: 357 SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERS 416

Query: 804 NCIHHILKQHLHVPEQ 819
           + I+H   Q  H  E+
Sbjct: 417 SLINH---QRTHTGEK 429



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 22/183 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  PY+C  C+   + K+ L  H R H+GE+PY C 
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECS 602

Query: 703 ICHYPFTVKANCERHLRKK------HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
           +C   F  K+   RHLR             RK   +    ++       +        C 
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE----KPFECS 658

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L  H RT         H G KP+ C EC  AF+ K   ++H   Q +H 
Sbjct: 659 ECGKAFSRKSHLIPHQRT---------HTGEKPYGCSECRKAFSQKSQLVNH---QRIHT 706

Query: 817 PEQ 819
            E+
Sbjct: 707 GEK 709



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 58/182 (31%), Positives = 74/182 (40%), Gaps = 14/182 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H G  PY C+ C      K+ LI H RTH+GE+PY C 
Sbjct: 487 YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 703 ICHYPFTVKANCERHLRKK--HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   F  K++   H R          +D EK     S                C LC +
Sbjct: 547 ECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD 820
                  L  H+RT         H G KP+EC EC  AF  K + I+H   Q +H  E+ 
Sbjct: 607 AFFEKSELIRHLRT---------HTGEKPYECNECRKAFREKSSLINH---QRIHTGEKP 654

Query: 821 IE 822
            E
Sbjct: 655 FE 656



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 95/387 (24%), Positives = 141/387 (36%), Gaps = 75/387 (19%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   SSL  H  THTG+KP  C +C   FS KS+   HQ+   G       + 
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464

Query: 1308 GLIPQSKESDVGSHDSTDSQSD----AETAAAAGEVLDLTSRDREQPSEGATELRQVAGD 1363
            G    S++S +  H  T +       +E   A  E L LT+  R    E      +  G 
Sbjct: 465  GKA-FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE-CGK 522

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
            A  +++        H   H R  +H  E+ +   E  G A G +   +++Q         
Sbjct: 523  AFCQKS--------HLISHQR--THTGEKPYECSEC-GKAFGEKSSLATHQRTH------ 565

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD------ 1477
                               + E+   C  C K+F     L+ H++ H  ++P +      
Sbjct: 566  -------------------TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 1478 ---EKGDGA----STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPS 1530
               EK +      +   E P    E  +   E  + +       GE P E          
Sbjct: 607  AFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFEC--------- 657

Query: 1531 DGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHT 1590
               S   K  S KS      +T +         ++   CS C K F     L  H R HT
Sbjct: 658  ---SECGKAFSRKSHLIPHQRTHT--------GEKPYGCSECRKAFSQKSQLVNHQRIHT 706

Query: 1591 GERPYKCQTCERTFTLKHSLVRHQRIH 1617
            GE+PY+C  C + F+ K  L+ HQR H
Sbjct: 707  GEKPYRCIECGKAFSQKSQLINHQRTH 733



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 60/202 (29%), Positives = 84/202 (41%), Gaps = 26/202 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  P+ C  C    + K+ LI H  TH+GE+P+IC 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKN---IEYVSSSAAELVDAFCAPDTVCRLCG 759
            C   F+ K+   RH R    +   +  E      E +S +  + +     P  VC  CG
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP-YVCSECG 521

Query: 760 EDLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAAFA 800
           +       L  H RTH          CG+  G           H G KP+EC++C  AF+
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581

Query: 801 AKRNCIHHILKQHLHVPEQDIE 822
            K     H   Q +H  E+  E
Sbjct: 582 QKSQLNTH---QRIHTGEKPYE 600



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 49/172 (28%), Positives = 71/172 (41%), Gaps = 19/172 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY CN C    ++K+ LI H R H+GE+P+ C+
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECR 350

Query: 703 ICHYPFTVKANCERHLRKKH------LKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F+ K+    H R             RK   +  E +        +        C 
Sbjct: 351 ECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEK----PYECS 406

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            C +  +   +L  H RTH G          KP  C +C  AF+ K + I H
Sbjct: 407 ECRKAFRERSSLINHQRTHTGE---------KPHGCIQCGKAFSQKSHLISH 449



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 96/441 (21%), Positives = 152/441 (34%), Gaps = 70/441 (15%)

Query: 1196 FLQTAEDNTQDEVAGAPADHH----------GPSDEEQGSPPEDKLLRAKRNSYTNCLQK 1245
            F+   + N++ ++ G    HH          G ++ +  +  ++  L +K       L+ 
Sbjct: 120  FVPLRKSNSEGDLDGLILKHHLDLLIPKGDYGKAESDDFNVFDNFFLHSKPEDTDTWLKY 179

Query: 1246 ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLR-----KHGVT 1300
              C      +  +  +  H     G+K + C +C   FS K +  +HQ R       G  
Sbjct: 180  YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCG 238

Query: 1301 TCSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQV 1360
             C        PQ  +S   +H  T +       +  G+          Q S+  +  R  
Sbjct: 239  NC----GKTFPQ--KSQFITHHRTHTGEKPYNCSQCGKAF-------SQKSQLTSHQRTH 285

Query: 1361 AGDAPVEQATAETASPVHREEH--GRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDL 1418
             G+ P E    E      R+ H      +H  E+ +G  E  G A   + +  ++Q +  
Sbjct: 286  TGEKPYE--CGECGKAFSRKSHLISHWRTHTGEKPYGCNE-CGRAFSEKSNLINHQRIH- 341

Query: 1419 DFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDE 1478
                                    + E+   C  CGK+F     L  H + H   +P   
Sbjct: 342  ------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG- 376

Query: 1479 KGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPA--EKLAEETEGPSDGESAA 1536
              D      E  +    Q     E P E  E      E  +        T     G    
Sbjct: 377  CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQC 436

Query: 1537 EKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYK 1596
             K  S+KS       T +         ++  +CS C K F     L RH R+HTGE+PY+
Sbjct: 437  GKAFSQKSHLISHQMTHT--------GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 1597 CQTCERTFTLKHSLVRHQRIH 1617
            C  C + F+ K SL  HQRIH
Sbjct: 489  CSECGKAFSEKLSLTNHQRIH 509



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 38/181 (20%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           LY C  C + F+    L  H   H+    + C  C      K+  I H RTH+GE+PY C
Sbjct: 206 LYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNC 265

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGED 761
             C   F+ K+    H R           EK  E                   C  CG+ 
Sbjct: 266 SQCGKAFSQKSQLTSHQR-------THTGEKPYE-------------------CGECGKA 299

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDI 821
                 L  H RT         H G KP+ C EC  AF+ K N I+H   Q +H  E+  
Sbjct: 300 FSRKSHLISHWRT---------HTGEKPYGCNECGRAFSEKSNLINH---QRIHTGEKPF 347

Query: 822 E 822
           E
Sbjct: 348 E 348



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 28/82 (34%), Positives = 41/82 (50%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PY C+ C    + K+ L+ H R H+GE+PY C 
Sbjct: 655 FECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCI 714

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F+ K+    H R   +K
Sbjct: 715 ECGKAFSQKSQLINHQRTHTVK 736



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 5/110 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK 1628
            C  C K F        H R+HTGE+PY C  C + F+ K  L  HQR H         G+
Sbjct: 237  CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGE 295

Query: 1629 DSDKEERGEEDSENESTHSGNNAVSENEAELA----PNASNHMAVTRSRK 1674
                  R      +  TH+G      NE   A     N  NH  +    K
Sbjct: 296  CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
            C  C + F   S L  H   HTG+KP+ C +C   FS KS    HQ R H V
Sbjct: 685  CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQ-RTHTV 735



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 34/140 (24%), Positives = 50/140 (35%), Gaps = 38/140 (27%)

Query: 683 KAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAA 742
           K+ +I + R   GE+ Y C  C   F+ K +  +H + +H++    DI            
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIR----DIAFG--------- 236

Query: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802
                       C  CG+          H RTH G          KP+ C +C  AF+ K
Sbjct: 237 ------------CGNCGKTFPQKSQFITHHRTHTGE---------KPYNCSQCGKAFSQK 275

Query: 803 RNCIHHILKQHLHVPEQDIE 822
                H   Q  H  E+  E
Sbjct: 276 SQLTSH---QRTHTGEKPYE 292


>gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1
            [Homo sapiens]
          Length = 738

 Score =  111 bits (277), Expect = 7e-24
 Identities = 94/373 (25%), Positives = 138/373 (36%), Gaps = 19/373 (5%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L  H  THTG+KP+ C +C   FS KSN   HQ    G      R  
Sbjct: 293  CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G     K   V  H +         +       + +   R Q            G+ P E
Sbjct: 353  GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH--------TGEKPYE 404

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---DLDFATKL 1424
             +    A            +H  E+ HG  +  G A   +    S+Q     +  F    
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQC-GKAFSQKSHLISHQMTHTGEKPFICSK 463

Query: 1425 MDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGAS 1484
                 +            + E+   C  CGK+F    +L+ H++ H  ++P      G +
Sbjct: 464  CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523

Query: 1485 TAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKS 1544
              ++       Q     E P E  E     GE  +    + T     GE   E R  EK+
Sbjct: 524  FCQKS-HLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTH---TGEKPYECRDCEKA 579

Query: 1545 DDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTF 1604
               K       +       ++   CS+C K F+   +L RH+R+HTGE+PY+C  C + F
Sbjct: 580  FSQKSQLNTHQRI---HTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAF 636

Query: 1605 TLKHSLVRHQRIH 1617
              K SL+ HQRIH
Sbjct: 637  REKSSLINHQRIH 649



 Score =  106 bits (265), Expect = 2e-22
 Identities = 79/314 (25%), Positives = 132/314 (42%), Gaps = 10/314 (3%)

Query: 31  TENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNT 90
           T  G  P G     K          +Q T   +  + C  C K  + + QL  H R H  
Sbjct: 424 THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTH-- 481

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
            TG   + CS CGK+ S   SL  H  +H+GE+PY C+ CG++F    ++  H + H  +
Sbjct: 482 -TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGE 540

Query: 151 PNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVF 208
                +    +  ++  L++ ++ +H  E   E     K   +  Q    ++    ++ +
Sbjct: 541 KPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 209 HCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM- 266
            C +C K F  K  L  H+ TH+ + P  C+ C   FR    L+ H  +   + P +   
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 267 -GRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKA 324
            G+ F + +  IP      G   + C +  +  SQ     N +R  + +  + C  C KA
Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719

Query: 325 FPMLCSLALHKQTH 338
           F     L  H++TH
Sbjct: 720 FSQKSQLINHQRTH 733



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 84/317 (26%), Positives = 122/317 (38%), Gaps = 21/317 (6%)

Query: 65  SYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP 124
           ++ C  C K    + Q   H   H T TG   ++CS CGK+ S  S L  H   H+GE+P
Sbjct: 234 AFGCGNCGKTFPQKSQFITH---HRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKP 290

Query: 125 YKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           Y+C  CG++F+   ++  H + H  +          +  ++  L + +++ H  E   E 
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRI-HTGEKPFEC 349

Query: 185 PAPAKKMVEDGQ--SGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
               K      Q  +        + F C  C K F  K  L  H   H+ + P  C  C 
Sbjct: 350 RECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECR 409

Query: 242 VTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSCRK----FP 295
             FR    L+ H      + P   +  G+ F Q +  I       G   F C K    F 
Sbjct: 410 KAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFS 469

Query: 296 RISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPG 355
           R SQ       +R  + +  + C  C KAF    SL  H++ H       EKP      G
Sbjct: 470 RKSQL---VRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG-----EKPYVCSECG 521

Query: 356 DALDQKGFLALLGLQHT 372
            A  QK  L      HT
Sbjct: 522 KAFCQKSHLISHQRTHT 538



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 81/312 (25%), Positives = 122/312 (39%), Gaps = 37/312 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C K  + +  L  H   H   TG     CS CGK+ S  S L RH
Sbjct: 421 HQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRH 477

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+PY+C+ CG++F+   ++  H +IH  +     +    +  ++  L S ++ +
Sbjct: 478 QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQR-T 536

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKK--ADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           H  E   E     K   E       ++    ++ + C  C K F  K  L TH   H+ +
Sbjct: 537 HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGE 596

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            P  C +C   F     L+RH       L      +P+  N                 CR
Sbjct: 597 KPYECSLCRKAFFEKSELIRH-------LRTHTGEKPYECNE----------------CR 633

Query: 293 KFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATP 352
           K  R   +    N +R  + +  F C  C KAF     L  H++TH       EKP    
Sbjct: 634 KAFREKSSLI--NHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTG-----EKPYGCS 686

Query: 353 LPGDALDQKGFL 364
               A  QK  L
Sbjct: 687 ECRKAFSQKSQL 698



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 57/185 (30%), Positives = 73/185 (39%), Gaps = 45/185 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y CR C + F+    L  H R H G  PY+C++C     +K+ LIRHLRTH+GE+PY C 
Sbjct: 571 YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECN 630

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++   H R   +    K  E                       C  CG+  
Sbjct: 631 ECRKAFREKSSLINHQR---IHTGEKPFE-----------------------CSECGKAF 664

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+ C EC  AF+ K 
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 804 NCIHH 808
             I+H
Sbjct: 725 QLINH 729



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 82/329 (24%), Positives = 127/329 (38%), Gaps = 47/329 (14%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +  T   +  YNC  C K  + + QLT H R H   TG   + C  CGK+ S  S L  H
Sbjct: 253 HHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---TGEKPYECGECGKAFSRKSHLISH 309

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDP---------------------NSA 154
              H+GE+PY C  CG++F+   N+  H +IH  +                       + 
Sbjct: 310 WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTH 369

Query: 155 TATAP--PSPLKRRRLSSKRKLSHDAESEREDP---APAKKMVEDGQSGDLEKKA---DE 206
           T T P   S  ++        + H      E P   +  +K   +  S    ++    ++
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429

Query: 207 VFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA 265
              C  C K F  K  L +H  TH+ + P  C  C   F     L+RH      + P + 
Sbjct: 430 PHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYEC 489

Query: 266 M--GRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNL----RRCISEQHRFVCD 319
              G+ F +            G   + C +     +A+C+ +     +R  + +  + C 
Sbjct: 490 SECGKAFSEKLSLTNHQRIHTGEKPYVCSE---CGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 320 TCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C KAF    SLA H++TH       EKP
Sbjct: 547 ECGKAFGEKSSLATHQRTHTG-----EKP 570



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 59/196 (30%), Positives = 77/196 (39%), Gaps = 48/196 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY+C  C    + K+ LI H RTH+GE+PY C 
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCN 322

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+N   H R   +    K  E                       CR CG+  
Sbjct: 323 ECGRAFSEKSNLINHQR---IHTGEKPFE-----------------------CRECGKAF 356

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+EC EC  AF  + 
Sbjct: 357 SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERS 416

Query: 804 NCIHHILKQHLHVPEQ 819
           + I+H   Q  H  E+
Sbjct: 417 SLINH---QRTHTGEK 429



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 22/183 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  PY+C  C+   + K+ L  H R H+GE+PY C 
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECS 602

Query: 703 ICHYPFTVKANCERHLRKK------HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
           +C   F  K+   RHLR             RK   +    ++       +        C 
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE----KPFECS 658

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L  H RT         H G KP+ C EC  AF+ K   ++H   Q +H 
Sbjct: 659 ECGKAFSRKSHLIPHQRT---------HTGEKPYGCSECRKAFSQKSQLVNH---QRIHT 706

Query: 817 PEQ 819
            E+
Sbjct: 707 GEK 709



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 58/182 (31%), Positives = 74/182 (40%), Gaps = 14/182 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H G  PY C+ C      K+ LI H RTH+GE+PY C 
Sbjct: 487 YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 703 ICHYPFTVKANCERHLRKK--HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   F  K++   H R          +D EK     S                C LC +
Sbjct: 547 ECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD 820
                  L  H+RT         H G KP+EC EC  AF  K + I+H   Q +H  E+ 
Sbjct: 607 AFFEKSELIRHLRT---------HTGEKPYECNECRKAFREKSSLINH---QRIHTGEKP 654

Query: 821 IE 822
            E
Sbjct: 655 FE 656



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 95/387 (24%), Positives = 141/387 (36%), Gaps = 75/387 (19%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   SSL  H  THTG+KP  C +C   FS KS+   HQ+   G       + 
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464

Query: 1308 GLIPQSKESDVGSHDSTDSQSD----AETAAAAGEVLDLTSRDREQPSEGATELRQVAGD 1363
            G    S++S +  H  T +       +E   A  E L LT+  R    E      +  G 
Sbjct: 465  GKA-FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE-CGK 522

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
            A  +++        H   H R  +H  E+ +   E  G A G +   +++Q         
Sbjct: 523  AFCQKS--------HLISHQR--THTGEKPYECSEC-GKAFGEKSSLATHQRTH------ 565

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD------ 1477
                               + E+   C  C K+F     L+ H++ H  ++P +      
Sbjct: 566  -------------------TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 1478 ---EKGDGA----STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPS 1530
               EK +      +   E P    E  +   E  + +       GE P E          
Sbjct: 607  AFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFEC--------- 657

Query: 1531 DGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHT 1590
               S   K  S KS      +T +         ++   CS C K F     L  H R HT
Sbjct: 658  ---SECGKAFSRKSHLIPHQRTHT--------GEKPYGCSECRKAFSQKSQLVNHQRIHT 706

Query: 1591 GERPYKCQTCERTFTLKHSLVRHQRIH 1617
            GE+PY+C  C + F+ K  L+ HQR H
Sbjct: 707  GEKPYRCIECGKAFSQKSQLINHQRTH 733



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 60/202 (29%), Positives = 84/202 (41%), Gaps = 26/202 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  P+ C  C    + K+ LI H  TH+GE+P+IC 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKN---IEYVSSSAAELVDAFCAPDTVCRLCG 759
            C   F+ K+   RH R    +   +  E      E +S +  + +     P  VC  CG
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP-YVCSECG 521

Query: 760 EDLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAAFA 800
           +       L  H RTH          CG+  G           H G KP+EC++C  AF+
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581

Query: 801 AKRNCIHHILKQHLHVPEQDIE 822
            K     H   Q +H  E+  E
Sbjct: 582 QKSQLNTH---QRIHTGEKPYE 600



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 49/172 (28%), Positives = 71/172 (41%), Gaps = 19/172 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY CN C    ++K+ LI H R H+GE+P+ C+
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECR 350

Query: 703 ICHYPFTVKANCERHLRKKH------LKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F+ K+    H R             RK   +  E +        +        C 
Sbjct: 351 ECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEK----PYECS 406

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            C +  +   +L  H RTH G          KP  C +C  AF+ K + I H
Sbjct: 407 ECRKAFRERSSLINHQRTHTGE---------KPHGCIQCGKAFSQKSHLISH 449



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 96/441 (21%), Positives = 152/441 (34%), Gaps = 70/441 (15%)

Query: 1196 FLQTAEDNTQDEVAGAPADHH----------GPSDEEQGSPPEDKLLRAKRNSYTNCLQK 1245
            F+   + N++ ++ G    HH          G ++ +  +  ++  L +K       L+ 
Sbjct: 120  FVPLRKSNSEGDLDGLILKHHLDLLIPKGDYGKAESDDFNVFDNFFLHSKPEDTDTWLKY 179

Query: 1246 ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLR-----KHGVT 1300
              C      +  +  +  H     G+K + C +C   FS K +  +HQ R       G  
Sbjct: 180  YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCG 238

Query: 1301 TCSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQV 1360
             C        PQ  +S   +H  T +       +  G+          Q S+  +  R  
Sbjct: 239  NC----GKTFPQ--KSQFITHHRTHTGEKPYNCSQCGKAF-------SQKSQLTSHQRTH 285

Query: 1361 AGDAPVEQATAETASPVHREEH--GRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDL 1418
             G+ P E    E      R+ H      +H  E+ +G  E  G A   + +  ++Q +  
Sbjct: 286  TGEKPYE--CGECGKAFSRKSHLISHWRTHTGEKPYGCNE-CGRAFSEKSNLINHQRIH- 341

Query: 1419 DFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDE 1478
                                    + E+   C  CGK+F     L  H + H   +P   
Sbjct: 342  ------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG- 376

Query: 1479 KGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPA--EKLAEETEGPSDGESAA 1536
              D      E  +    Q     E P E  E      E  +        T     G    
Sbjct: 377  CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQC 436

Query: 1537 EKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYK 1596
             K  S+KS       T +         ++  +CS C K F     L RH R+HTGE+PY+
Sbjct: 437  GKAFSQKSHLISHQMTHT--------GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 1597 CQTCERTFTLKHSLVRHQRIH 1617
            C  C + F+ K SL  HQRIH
Sbjct: 489  CSECGKAFSEKLSLTNHQRIH 509



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 38/181 (20%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           LY C  C + F+    L  H   H+    + C  C      K+  I H RTH+GE+PY C
Sbjct: 206 LYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNC 265

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGED 761
             C   F+ K+    H R           EK  E                   C  CG+ 
Sbjct: 266 SQCGKAFSQKSQLTSHQR-------THTGEKPYE-------------------CGECGKA 299

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDI 821
                 L  H RT         H G KP+ C EC  AF+ K N I+H   Q +H  E+  
Sbjct: 300 FSRKSHLISHWRT---------HTGEKPYGCNECGRAFSEKSNLINH---QRIHTGEKPF 347

Query: 822 E 822
           E
Sbjct: 348 E 348



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 28/82 (34%), Positives = 41/82 (50%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PY C+ C    + K+ L+ H R H+GE+PY C 
Sbjct: 655 FECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCI 714

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F+ K+    H R   +K
Sbjct: 715 ECGKAFSQKSQLINHQRTHTVK 736



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 5/110 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK 1628
            C  C K F        H R+HTGE+PY C  C + F+ K  L  HQR H         G+
Sbjct: 237  CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGE 295

Query: 1629 DSDKEERGEEDSENESTHSGNNAVSENEAELA----PNASNHMAVTRSRK 1674
                  R      +  TH+G      NE   A     N  NH  +    K
Sbjct: 296  CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
            C  C + F   S L  H   HTG+KP+ C +C   FS KS    HQ R H V
Sbjct: 685  CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQ-RTHTV 735



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 34/140 (24%), Positives = 50/140 (35%), Gaps = 38/140 (27%)

Query: 683 KAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAA 742
           K+ +I + R   GE+ Y C  C   F+ K +  +H + +H++    DI            
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIR----DIAFG--------- 236

Query: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802
                       C  CG+          H RTH G          KP+ C +C  AF+ K
Sbjct: 237 ------------CGNCGKTFPQKSQFITHHRTHTGE---------KPYNCSQCGKAFSQK 275

Query: 803 RNCIHHILKQHLHVPEQDIE 822
                H   Q  H  E+  E
Sbjct: 276 SQLTSH---QRTHTGEKPYE 292


>gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3
            [Homo sapiens]
          Length = 738

 Score =  111 bits (277), Expect = 7e-24
 Identities = 94/373 (25%), Positives = 138/373 (36%), Gaps = 19/373 (5%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L  H  THTG+KP+ C +C   FS KSN   HQ    G      R  
Sbjct: 293  CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G     K   V  H +         +       + +   R Q            G+ P E
Sbjct: 353  GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH--------TGEKPYE 404

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---DLDFATKL 1424
             +    A            +H  E+ HG  +  G A   +    S+Q     +  F    
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQC-GKAFSQKSHLISHQMTHTGEKPFICSK 463

Query: 1425 MDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGAS 1484
                 +            + E+   C  CGK+F    +L+ H++ H  ++P      G +
Sbjct: 464  CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523

Query: 1485 TAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKS 1544
              ++       Q     E P E  E     GE  +    + T     GE   E R  EK+
Sbjct: 524  FCQKS-HLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTH---TGEKPYECRDCEKA 579

Query: 1545 DDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTF 1604
               K       +       ++   CS+C K F+   +L RH+R+HTGE+PY+C  C + F
Sbjct: 580  FSQKSQLNTHQRI---HTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAF 636

Query: 1605 TLKHSLVRHQRIH 1617
              K SL+ HQRIH
Sbjct: 637  REKSSLINHQRIH 649



 Score =  106 bits (265), Expect = 2e-22
 Identities = 79/314 (25%), Positives = 132/314 (42%), Gaps = 10/314 (3%)

Query: 31  TENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNT 90
           T  G  P G     K          +Q T   +  + C  C K  + + QL  H R H  
Sbjct: 424 THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTH-- 481

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
            TG   + CS CGK+ S   SL  H  +H+GE+PY C+ CG++F    ++  H + H  +
Sbjct: 482 -TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGE 540

Query: 151 PNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVF 208
                +    +  ++  L++ ++ +H  E   E     K   +  Q    ++    ++ +
Sbjct: 541 KPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 209 HCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM- 266
            C +C K F  K  L  H+ TH+ + P  C+ C   FR    L+ H  +   + P +   
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 267 -GRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKA 324
            G+ F + +  IP      G   + C +  +  SQ     N +R  + +  + C  C KA
Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719

Query: 325 FPMLCSLALHKQTH 338
           F     L  H++TH
Sbjct: 720 FSQKSQLINHQRTH 733



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 84/317 (26%), Positives = 122/317 (38%), Gaps = 21/317 (6%)

Query: 65  SYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP 124
           ++ C  C K    + Q   H   H T TG   ++CS CGK+ S  S L  H   H+GE+P
Sbjct: 234 AFGCGNCGKTFPQKSQFITH---HRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKP 290

Query: 125 YKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           Y+C  CG++F+   ++  H + H  +          +  ++  L + +++ H  E   E 
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRI-HTGEKPFEC 349

Query: 185 PAPAKKMVEDGQ--SGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
               K      Q  +        + F C  C K F  K  L  H   H+ + P  C  C 
Sbjct: 350 RECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECR 409

Query: 242 VTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSCRK----FP 295
             FR    L+ H      + P   +  G+ F Q +  I       G   F C K    F 
Sbjct: 410 KAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFS 469

Query: 296 RISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPG 355
           R SQ       +R  + +  + C  C KAF    SL  H++ H       EKP      G
Sbjct: 470 RKSQL---VRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG-----EKPYVCSECG 521

Query: 356 DALDQKGFLALLGLQHT 372
            A  QK  L      HT
Sbjct: 522 KAFCQKSHLISHQRTHT 538



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 81/312 (25%), Positives = 122/312 (39%), Gaps = 37/312 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C K  + +  L  H   H   TG     CS CGK+ S  S L RH
Sbjct: 421 HQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRH 477

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+PY+C+ CG++F+   ++  H +IH  +     +    +  ++  L S ++ +
Sbjct: 478 QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQR-T 536

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKK--ADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           H  E   E     K   E       ++    ++ + C  C K F  K  L TH   H+ +
Sbjct: 537 HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGE 596

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            P  C +C   F     L+RH       L      +P+  N                 CR
Sbjct: 597 KPYECSLCRKAFFEKSELIRH-------LRTHTGEKPYECNE----------------CR 633

Query: 293 KFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATP 352
           K  R   +    N +R  + +  F C  C KAF     L  H++TH       EKP    
Sbjct: 634 KAFREKSSLI--NHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTG-----EKPYGCS 686

Query: 353 LPGDALDQKGFL 364
               A  QK  L
Sbjct: 687 ECRKAFSQKSQL 698



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 57/185 (30%), Positives = 73/185 (39%), Gaps = 45/185 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y CR C + F+    L  H R H G  PY+C++C     +K+ LIRHLRTH+GE+PY C 
Sbjct: 571 YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECN 630

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++   H R   +    K  E                       C  CG+  
Sbjct: 631 ECRKAFREKSSLINHQR---IHTGEKPFE-----------------------CSECGKAF 664

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+ C EC  AF+ K 
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 804 NCIHH 808
             I+H
Sbjct: 725 QLINH 729



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 82/329 (24%), Positives = 127/329 (38%), Gaps = 47/329 (14%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +  T   +  YNC  C K  + + QLT H R H   TG   + C  CGK+ S  S L  H
Sbjct: 253 HHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---TGEKPYECGECGKAFSRKSHLISH 309

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDP---------------------NSA 154
              H+GE+PY C  CG++F+   N+  H +IH  +                       + 
Sbjct: 310 WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTH 369

Query: 155 TATAP--PSPLKRRRLSSKRKLSHDAESEREDP---APAKKMVEDGQSGDLEKKA---DE 206
           T T P   S  ++        + H      E P   +  +K   +  S    ++    ++
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429

Query: 207 VFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA 265
              C  C K F  K  L +H  TH+ + P  C  C   F     L+RH      + P + 
Sbjct: 430 PHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYEC 489

Query: 266 M--GRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNL----RRCISEQHRFVCD 319
              G+ F +            G   + C +     +A+C+ +     +R  + +  + C 
Sbjct: 490 SECGKAFSEKLSLTNHQRIHTGEKPYVCSE---CGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 320 TCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C KAF    SLA H++TH       EKP
Sbjct: 547 ECGKAFGEKSSLATHQRTHTG-----EKP 570



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 59/196 (30%), Positives = 77/196 (39%), Gaps = 48/196 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY+C  C    + K+ LI H RTH+GE+PY C 
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCN 322

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+N   H R   +    K  E                       CR CG+  
Sbjct: 323 ECGRAFSEKSNLINHQR---IHTGEKPFE-----------------------CRECGKAF 356

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+EC EC  AF  + 
Sbjct: 357 SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERS 416

Query: 804 NCIHHILKQHLHVPEQ 819
           + I+H   Q  H  E+
Sbjct: 417 SLINH---QRTHTGEK 429



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 22/183 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  PY+C  C+   + K+ L  H R H+GE+PY C 
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECS 602

Query: 703 ICHYPFTVKANCERHLRKK------HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
           +C   F  K+   RHLR             RK   +    ++       +        C 
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE----KPFECS 658

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L  H RT         H G KP+ C EC  AF+ K   ++H   Q +H 
Sbjct: 659 ECGKAFSRKSHLIPHQRT---------HTGEKPYGCSECRKAFSQKSQLVNH---QRIHT 706

Query: 817 PEQ 819
            E+
Sbjct: 707 GEK 709



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 58/182 (31%), Positives = 74/182 (40%), Gaps = 14/182 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H G  PY C+ C      K+ LI H RTH+GE+PY C 
Sbjct: 487 YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 703 ICHYPFTVKANCERHLRKK--HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   F  K++   H R          +D EK     S                C LC +
Sbjct: 547 ECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD 820
                  L  H+RT         H G KP+EC EC  AF  K + I+H   Q +H  E+ 
Sbjct: 607 AFFEKSELIRHLRT---------HTGEKPYECNECRKAFREKSSLINH---QRIHTGEKP 654

Query: 821 IE 822
            E
Sbjct: 655 FE 656



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 95/387 (24%), Positives = 141/387 (36%), Gaps = 75/387 (19%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   SSL  H  THTG+KP  C +C   FS KS+   HQ+   G       + 
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464

Query: 1308 GLIPQSKESDVGSHDSTDSQSD----AETAAAAGEVLDLTSRDREQPSEGATELRQVAGD 1363
            G    S++S +  H  T +       +E   A  E L LT+  R    E      +  G 
Sbjct: 465  GKA-FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE-CGK 522

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
            A  +++        H   H R  +H  E+ +   E  G A G +   +++Q         
Sbjct: 523  AFCQKS--------HLISHQR--THTGEKPYECSEC-GKAFGEKSSLATHQRTH------ 565

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD------ 1477
                               + E+   C  C K+F     L+ H++ H  ++P +      
Sbjct: 566  -------------------TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 1478 ---EKGDGA----STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPS 1530
               EK +      +   E P    E  +   E  + +       GE P E          
Sbjct: 607  AFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFEC--------- 657

Query: 1531 DGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHT 1590
               S   K  S KS      +T +         ++   CS C K F     L  H R HT
Sbjct: 658  ---SECGKAFSRKSHLIPHQRTHT--------GEKPYGCSECRKAFSQKSQLVNHQRIHT 706

Query: 1591 GERPYKCQTCERTFTLKHSLVRHQRIH 1617
            GE+PY+C  C + F+ K  L+ HQR H
Sbjct: 707  GEKPYRCIECGKAFSQKSQLINHQRTH 733



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 60/202 (29%), Positives = 84/202 (41%), Gaps = 26/202 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  P+ C  C    + K+ LI H  TH+GE+P+IC 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKN---IEYVSSSAAELVDAFCAPDTVCRLCG 759
            C   F+ K+   RH R    +   +  E      E +S +  + +     P  VC  CG
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP-YVCSECG 521

Query: 760 EDLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAAFA 800
           +       L  H RTH          CG+  G           H G KP+EC++C  AF+
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581

Query: 801 AKRNCIHHILKQHLHVPEQDIE 822
            K     H   Q +H  E+  E
Sbjct: 582 QKSQLNTH---QRIHTGEKPYE 600



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 49/172 (28%), Positives = 71/172 (41%), Gaps = 19/172 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY CN C    ++K+ LI H R H+GE+P+ C+
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECR 350

Query: 703 ICHYPFTVKANCERHLRKKH------LKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F+ K+    H R             RK   +  E +        +        C 
Sbjct: 351 ECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEK----PYECS 406

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            C +  +   +L  H RTH G          KP  C +C  AF+ K + I H
Sbjct: 407 ECRKAFRERSSLINHQRTHTGE---------KPHGCIQCGKAFSQKSHLISH 449



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 96/441 (21%), Positives = 152/441 (34%), Gaps = 70/441 (15%)

Query: 1196 FLQTAEDNTQDEVAGAPADHH----------GPSDEEQGSPPEDKLLRAKRNSYTNCLQK 1245
            F+   + N++ ++ G    HH          G ++ +  +  ++  L +K       L+ 
Sbjct: 120  FVPLRKSNSEGDLDGLILKHHLDLLIPKGDYGKAESDDFNVFDNFFLHSKPEDTDTWLKY 179

Query: 1246 ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLR-----KHGVT 1300
              C      +  +  +  H     G+K + C +C   FS K +  +HQ R       G  
Sbjct: 180  YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCG 238

Query: 1301 TCSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQV 1360
             C        PQ  +S   +H  T +       +  G+          Q S+  +  R  
Sbjct: 239  NC----GKTFPQ--KSQFITHHRTHTGEKPYNCSQCGKAF-------SQKSQLTSHQRTH 285

Query: 1361 AGDAPVEQATAETASPVHREEH--GRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDL 1418
             G+ P E    E      R+ H      +H  E+ +G  E  G A   + +  ++Q +  
Sbjct: 286  TGEKPYE--CGECGKAFSRKSHLISHWRTHTGEKPYGCNE-CGRAFSEKSNLINHQRIH- 341

Query: 1419 DFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDE 1478
                                    + E+   C  CGK+F     L  H + H   +P   
Sbjct: 342  ------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG- 376

Query: 1479 KGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPA--EKLAEETEGPSDGESAA 1536
              D      E  +    Q     E P E  E      E  +        T     G    
Sbjct: 377  CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQC 436

Query: 1537 EKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYK 1596
             K  S+KS       T +         ++  +CS C K F     L RH R+HTGE+PY+
Sbjct: 437  GKAFSQKSHLISHQMTHT--------GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 1597 CQTCERTFTLKHSLVRHQRIH 1617
            C  C + F+ K SL  HQRIH
Sbjct: 489  CSECGKAFSEKLSLTNHQRIH 509



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 38/181 (20%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           LY C  C + F+    L  H   H+    + C  C      K+  I H RTH+GE+PY C
Sbjct: 206 LYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNC 265

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGED 761
             C   F+ K+    H R           EK  E                   C  CG+ 
Sbjct: 266 SQCGKAFSQKSQLTSHQR-------THTGEKPYE-------------------CGECGKA 299

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDI 821
                 L  H RT         H G KP+ C EC  AF+ K N I+H   Q +H  E+  
Sbjct: 300 FSRKSHLISHWRT---------HTGEKPYGCNECGRAFSEKSNLINH---QRIHTGEKPF 347

Query: 822 E 822
           E
Sbjct: 348 E 348



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 28/82 (34%), Positives = 41/82 (50%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PY C+ C    + K+ L+ H R H+GE+PY C 
Sbjct: 655 FECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCI 714

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F+ K+    H R   +K
Sbjct: 715 ECGKAFSQKSQLINHQRTHTVK 736



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 5/110 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK 1628
            C  C K F        H R+HTGE+PY C  C + F+ K  L  HQR H         G+
Sbjct: 237  CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGE 295

Query: 1629 DSDKEERGEEDSENESTHSGNNAVSENEAELA----PNASNHMAVTRSRK 1674
                  R      +  TH+G      NE   A     N  NH  +    K
Sbjct: 296  CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
            C  C + F   S L  H   HTG+KP+ C +C   FS KS    HQ R H V
Sbjct: 685  CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQ-RTHTV 735



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 34/140 (24%), Positives = 50/140 (35%), Gaps = 38/140 (27%)

Query: 683 KAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAA 742
           K+ +I + R   GE+ Y C  C   F+ K +  +H + +H++    DI            
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIR----DIAFG--------- 236

Query: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802
                       C  CG+          H RTH G          KP+ C +C  AF+ K
Sbjct: 237 ------------CGNCGKTFPQKSQFITHHRTHTGE---------KPYNCSQCGKAFSQK 275

Query: 803 RNCIHHILKQHLHVPEQDIE 822
                H   Q  H  E+  E
Sbjct: 276 SQLTSH---QRTHTGEKPYE 292


>gi|188497655 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  111 bits (277), Expect = 7e-24
 Identities = 94/373 (25%), Positives = 138/373 (36%), Gaps = 19/373 (5%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L  H  THTG+KP+ C +C   FS KSN   HQ    G      R  
Sbjct: 293  CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G     K   V  H +         +       + +   R Q            G+ P E
Sbjct: 353  GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH--------TGEKPYE 404

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---DLDFATKL 1424
             +    A            +H  E+ HG  +  G A   +    S+Q     +  F    
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQC-GKAFSQKSHLISHQMTHTGEKPFICSK 463

Query: 1425 MDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGAS 1484
                 +            + E+   C  CGK+F    +L+ H++ H  ++P      G +
Sbjct: 464  CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523

Query: 1485 TAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKS 1544
              ++       Q     E P E  E     GE  +    + T     GE   E R  EK+
Sbjct: 524  FCQKS-HLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTH---TGEKPYECRDCEKA 579

Query: 1545 DDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTF 1604
               K       +       ++   CS+C K F+   +L RH+R+HTGE+PY+C  C + F
Sbjct: 580  FSQKSQLNTHQRI---HTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAF 636

Query: 1605 TLKHSLVRHQRIH 1617
              K SL+ HQRIH
Sbjct: 637  REKSSLINHQRIH 649



 Score =  106 bits (265), Expect = 2e-22
 Identities = 79/314 (25%), Positives = 132/314 (42%), Gaps = 10/314 (3%)

Query: 31  TENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNT 90
           T  G  P G     K          +Q T   +  + C  C K  + + QL  H R H  
Sbjct: 424 THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTH-- 481

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
            TG   + CS CGK+ S   SL  H  +H+GE+PY C+ CG++F    ++  H + H  +
Sbjct: 482 -TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGE 540

Query: 151 PNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVF 208
                +    +  ++  L++ ++ +H  E   E     K   +  Q    ++    ++ +
Sbjct: 541 KPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 209 HCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM- 266
            C +C K F  K  L  H+ TH+ + P  C+ C   FR    L+ H  +   + P +   
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 267 -GRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKA 324
            G+ F + +  IP      G   + C +  +  SQ     N +R  + +  + C  C KA
Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719

Query: 325 FPMLCSLALHKQTH 338
           F     L  H++TH
Sbjct: 720 FSQKSQLINHQRTH 733



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 84/317 (26%), Positives = 122/317 (38%), Gaps = 21/317 (6%)

Query: 65  SYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP 124
           ++ C  C K    + Q   H   H T TG   ++CS CGK+ S  S L  H   H+GE+P
Sbjct: 234 AFGCGNCGKTFPQKSQFITH---HRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKP 290

Query: 125 YKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           Y+C  CG++F+   ++  H + H  +          +  ++  L + +++ H  E   E 
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRI-HTGEKPFEC 349

Query: 185 PAPAKKMVEDGQ--SGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
               K      Q  +        + F C  C K F  K  L  H   H+ + P  C  C 
Sbjct: 350 RECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECR 409

Query: 242 VTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSCRK----FP 295
             FR    L+ H      + P   +  G+ F Q +  I       G   F C K    F 
Sbjct: 410 KAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFS 469

Query: 296 RISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPG 355
           R SQ       +R  + +  + C  C KAF    SL  H++ H       EKP      G
Sbjct: 470 RKSQL---VRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG-----EKPYVCSECG 521

Query: 356 DALDQKGFLALLGLQHT 372
            A  QK  L      HT
Sbjct: 522 KAFCQKSHLISHQRTHT 538



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 81/312 (25%), Positives = 122/312 (39%), Gaps = 37/312 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C K  + +  L  H   H   TG     CS CGK+ S  S L RH
Sbjct: 421 HQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRH 477

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+PY+C+ CG++F+   ++  H +IH  +     +    +  ++  L S ++ +
Sbjct: 478 QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQR-T 536

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKK--ADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           H  E   E     K   E       ++    ++ + C  C K F  K  L TH   H+ +
Sbjct: 537 HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGE 596

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            P  C +C   F     L+RH       L      +P+  N                 CR
Sbjct: 597 KPYECSLCRKAFFEKSELIRH-------LRTHTGEKPYECNE----------------CR 633

Query: 293 KFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATP 352
           K  R   +    N +R  + +  F C  C KAF     L  H++TH       EKP    
Sbjct: 634 KAFREKSSLI--NHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTG-----EKPYGCS 686

Query: 353 LPGDALDQKGFL 364
               A  QK  L
Sbjct: 687 ECRKAFSQKSQL 698



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 57/185 (30%), Positives = 73/185 (39%), Gaps = 45/185 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y CR C + F+    L  H R H G  PY+C++C     +K+ LIRHLRTH+GE+PY C 
Sbjct: 571 YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECN 630

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++   H R   +    K  E                       C  CG+  
Sbjct: 631 ECRKAFREKSSLINHQR---IHTGEKPFE-----------------------CSECGKAF 664

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+ C EC  AF+ K 
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 804 NCIHH 808
             I+H
Sbjct: 725 QLINH 729



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 82/329 (24%), Positives = 127/329 (38%), Gaps = 47/329 (14%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +  T   +  YNC  C K  + + QLT H R H   TG   + C  CGK+ S  S L  H
Sbjct: 253 HHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---TGEKPYECGECGKAFSRKSHLISH 309

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDP---------------------NSA 154
              H+GE+PY C  CG++F+   N+  H +IH  +                       + 
Sbjct: 310 WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTH 369

Query: 155 TATAP--PSPLKRRRLSSKRKLSHDAESEREDP---APAKKMVEDGQSGDLEKKA---DE 206
           T T P   S  ++        + H      E P   +  +K   +  S    ++    ++
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429

Query: 207 VFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA 265
              C  C K F  K  L +H  TH+ + P  C  C   F     L+RH      + P + 
Sbjct: 430 PHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYEC 489

Query: 266 M--GRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNL----RRCISEQHRFVCD 319
              G+ F +            G   + C +     +A+C+ +     +R  + +  + C 
Sbjct: 490 SECGKAFSEKLSLTNHQRIHTGEKPYVCSE---CGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 320 TCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C KAF    SLA H++TH       EKP
Sbjct: 547 ECGKAFGEKSSLATHQRTHTG-----EKP 570



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 59/196 (30%), Positives = 77/196 (39%), Gaps = 48/196 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY+C  C    + K+ LI H RTH+GE+PY C 
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCN 322

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+N   H R   +    K  E                       CR CG+  
Sbjct: 323 ECGRAFSEKSNLINHQR---IHTGEKPFE-----------------------CRECGKAF 356

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+EC EC  AF  + 
Sbjct: 357 SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERS 416

Query: 804 NCIHHILKQHLHVPEQ 819
           + I+H   Q  H  E+
Sbjct: 417 SLINH---QRTHTGEK 429



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 22/183 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  PY+C  C+   + K+ L  H R H+GE+PY C 
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECS 602

Query: 703 ICHYPFTVKANCERHLRKK------HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
           +C   F  K+   RHLR             RK   +    ++       +        C 
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE----KPFECS 658

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L  H RT         H G KP+ C EC  AF+ K   ++H   Q +H 
Sbjct: 659 ECGKAFSRKSHLIPHQRT---------HTGEKPYGCSECRKAFSQKSQLVNH---QRIHT 706

Query: 817 PEQ 819
            E+
Sbjct: 707 GEK 709



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 58/182 (31%), Positives = 74/182 (40%), Gaps = 14/182 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H G  PY C+ C      K+ LI H RTH+GE+PY C 
Sbjct: 487 YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 703 ICHYPFTVKANCERHLRKK--HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   F  K++   H R          +D EK     S                C LC +
Sbjct: 547 ECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD 820
                  L  H+RT         H G KP+EC EC  AF  K + I+H   Q +H  E+ 
Sbjct: 607 AFFEKSELIRHLRT---------HTGEKPYECNECRKAFREKSSLINH---QRIHTGEKP 654

Query: 821 IE 822
            E
Sbjct: 655 FE 656



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 95/387 (24%), Positives = 141/387 (36%), Gaps = 75/387 (19%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   SSL  H  THTG+KP  C +C   FS KS+   HQ+   G       + 
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464

Query: 1308 GLIPQSKESDVGSHDSTDSQSD----AETAAAAGEVLDLTSRDREQPSEGATELRQVAGD 1363
            G    S++S +  H  T +       +E   A  E L LT+  R    E      +  G 
Sbjct: 465  GKA-FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE-CGK 522

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
            A  +++        H   H R  +H  E+ +   E  G A G +   +++Q         
Sbjct: 523  AFCQKS--------HLISHQR--THTGEKPYECSEC-GKAFGEKSSLATHQRTH------ 565

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD------ 1477
                               + E+   C  C K+F     L+ H++ H  ++P +      
Sbjct: 566  -------------------TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 1478 ---EKGDGA----STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPS 1530
               EK +      +   E P    E  +   E  + +       GE P E          
Sbjct: 607  AFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFEC--------- 657

Query: 1531 DGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHT 1590
               S   K  S KS      +T +         ++   CS C K F     L  H R HT
Sbjct: 658  ---SECGKAFSRKSHLIPHQRTHT--------GEKPYGCSECRKAFSQKSQLVNHQRIHT 706

Query: 1591 GERPYKCQTCERTFTLKHSLVRHQRIH 1617
            GE+PY+C  C + F+ K  L+ HQR H
Sbjct: 707  GEKPYRCIECGKAFSQKSQLINHQRTH 733



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 60/202 (29%), Positives = 84/202 (41%), Gaps = 26/202 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  P+ C  C    + K+ LI H  TH+GE+P+IC 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKN---IEYVSSSAAELVDAFCAPDTVCRLCG 759
            C   F+ K+   RH R    +   +  E      E +S +  + +     P  VC  CG
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP-YVCSECG 521

Query: 760 EDLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAAFA 800
           +       L  H RTH          CG+  G           H G KP+EC++C  AF+
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581

Query: 801 AKRNCIHHILKQHLHVPEQDIE 822
            K     H   Q +H  E+  E
Sbjct: 582 QKSQLNTH---QRIHTGEKPYE 600



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 49/172 (28%), Positives = 71/172 (41%), Gaps = 19/172 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY CN C    ++K+ LI H R H+GE+P+ C+
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECR 350

Query: 703 ICHYPFTVKANCERHLRKKH------LKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F+ K+    H R             RK   +  E +        +        C 
Sbjct: 351 ECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEK----PYECS 406

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            C +  +   +L  H RTH G          KP  C +C  AF+ K + I H
Sbjct: 407 ECRKAFRERSSLINHQRTHTGE---------KPHGCIQCGKAFSQKSHLISH 449



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 96/441 (21%), Positives = 152/441 (34%), Gaps = 70/441 (15%)

Query: 1196 FLQTAEDNTQDEVAGAPADHH----------GPSDEEQGSPPEDKLLRAKRNSYTNCLQK 1245
            F+   + N++ ++ G    HH          G ++ +  +  ++  L +K       L+ 
Sbjct: 120  FVPLRKSNSEGDLDGLILKHHLDLLIPKGDYGKAESDDFNVFDNFFLHSKPEDTDTWLKY 179

Query: 1246 ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLR-----KHGVT 1300
              C      +  +  +  H     G+K + C +C   FS K +  +HQ R       G  
Sbjct: 180  YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCG 238

Query: 1301 TCSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQV 1360
             C        PQ  +S   +H  T +       +  G+          Q S+  +  R  
Sbjct: 239  NC----GKTFPQ--KSQFITHHRTHTGEKPYNCSQCGKAF-------SQKSQLTSHQRTH 285

Query: 1361 AGDAPVEQATAETASPVHREEH--GRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDL 1418
             G+ P E    E      R+ H      +H  E+ +G  E  G A   + +  ++Q +  
Sbjct: 286  TGEKPYE--CGECGKAFSRKSHLISHWRTHTGEKPYGCNE-CGRAFSEKSNLINHQRIH- 341

Query: 1419 DFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDE 1478
                                    + E+   C  CGK+F     L  H + H   +P   
Sbjct: 342  ------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG- 376

Query: 1479 KGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPA--EKLAEETEGPSDGESAA 1536
              D      E  +    Q     E P E  E      E  +        T     G    
Sbjct: 377  CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQC 436

Query: 1537 EKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYK 1596
             K  S+KS       T +         ++  +CS C K F     L RH R+HTGE+PY+
Sbjct: 437  GKAFSQKSHLISHQMTHT--------GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 1597 CQTCERTFTLKHSLVRHQRIH 1617
            C  C + F+ K SL  HQRIH
Sbjct: 489  CSECGKAFSEKLSLTNHQRIH 509



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 38/181 (20%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           LY C  C + F+    L  H   H+    + C  C      K+  I H RTH+GE+PY C
Sbjct: 206 LYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNC 265

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGED 761
             C   F+ K+    H R           EK  E                   C  CG+ 
Sbjct: 266 SQCGKAFSQKSQLTSHQR-------THTGEKPYE-------------------CGECGKA 299

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDI 821
                 L  H RT         H G KP+ C EC  AF+ K N I+H   Q +H  E+  
Sbjct: 300 FSRKSHLISHWRT---------HTGEKPYGCNECGRAFSEKSNLINH---QRIHTGEKPF 347

Query: 822 E 822
           E
Sbjct: 348 E 348



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 28/82 (34%), Positives = 41/82 (50%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PY C+ C    + K+ L+ H R H+GE+PY C 
Sbjct: 655 FECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCI 714

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F+ K+    H R   +K
Sbjct: 715 ECGKAFSQKSQLINHQRTHTVK 736



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 5/110 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK 1628
            C  C K F        H R+HTGE+PY C  C + F+ K  L  HQR H         G+
Sbjct: 237  CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGE 295

Query: 1629 DSDKEERGEEDSENESTHSGNNAVSENEAELA----PNASNHMAVTRSRK 1674
                  R      +  TH+G      NE   A     N  NH  +    K
Sbjct: 296  CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
            C  C + F   S L  H   HTG+KP+ C +C   FS KS    HQ R H V
Sbjct: 685  CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQ-RTHTV 735



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 34/140 (24%), Positives = 50/140 (35%), Gaps = 38/140 (27%)

Query: 683 KAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAA 742
           K+ +I + R   GE+ Y C  C   F+ K +  +H + +H++    DI            
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIR----DIAFG--------- 236

Query: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802
                       C  CG+          H RTH G          KP+ C +C  AF+ K
Sbjct: 237 ------------CGNCGKTFPQKSQFITHHRTHTGE---------KPYNCSQCGKAFSQK 275

Query: 803 RNCIHHILKQHLHVPEQDIE 822
                H   Q  H  E+  E
Sbjct: 276 SQLTSH---QRTHTGEKPYE 292


>gi|188497653 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  111 bits (277), Expect = 7e-24
 Identities = 94/373 (25%), Positives = 138/373 (36%), Gaps = 19/373 (5%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L  H  THTG+KP+ C +C   FS KSN   HQ    G      R  
Sbjct: 293  CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G     K   V  H +         +       + +   R Q            G+ P E
Sbjct: 353  GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIH--------TGEKPYE 404

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---DLDFATKL 1424
             +    A            +H  E+ HG  +  G A   +    S+Q     +  F    
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQC-GKAFSQKSHLISHQMTHTGEKPFICSK 463

Query: 1425 MDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGAS 1484
                 +            + E+   C  CGK+F    +L+ H++ H  ++P      G +
Sbjct: 464  CGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKA 523

Query: 1485 TAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKS 1544
              ++       Q     E P E  E     GE  +    + T     GE   E R  EK+
Sbjct: 524  FCQKS-HLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTH---TGEKPYECRDCEKA 579

Query: 1545 DDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTF 1604
               K       +       ++   CS+C K F+   +L RH+R+HTGE+PY+C  C + F
Sbjct: 580  FSQKSQLNTHQRI---HTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAF 636

Query: 1605 TLKHSLVRHQRIH 1617
              K SL+ HQRIH
Sbjct: 637  REKSSLINHQRIH 649



 Score =  106 bits (265), Expect = 2e-22
 Identities = 79/314 (25%), Positives = 132/314 (42%), Gaps = 10/314 (3%)

Query: 31  TENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNT 90
           T  G  P G     K          +Q T   +  + C  C K  + + QL  H R H  
Sbjct: 424 THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTH-- 481

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
            TG   + CS CGK+ S   SL  H  +H+GE+PY C+ CG++F    ++  H + H  +
Sbjct: 482 -TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGE 540

Query: 151 PNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVF 208
                +    +  ++  L++ ++ +H  E   E     K   +  Q    ++    ++ +
Sbjct: 541 KPYECSECGKAFGEKSSLATHQR-THTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599

Query: 209 HCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM- 266
            C +C K F  K  L  H+ TH+ + P  C+ C   FR    L+ H  +   + P +   
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSE 659

Query: 267 -GRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKA 324
            G+ F + +  IP      G   + C +  +  SQ     N +R  + +  + C  C KA
Sbjct: 660 CGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKA 719

Query: 325 FPMLCSLALHKQTH 338
           F     L  H++TH
Sbjct: 720 FSQKSQLINHQRTH 733



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 84/317 (26%), Positives = 122/317 (38%), Gaps = 21/317 (6%)

Query: 65  SYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP 124
           ++ C  C K    + Q   H   H T TG   ++CS CGK+ S  S L  H   H+GE+P
Sbjct: 234 AFGCGNCGKTFPQKSQFITH---HRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKP 290

Query: 125 YKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           Y+C  CG++F+   ++  H + H  +          +  ++  L + +++ H  E   E 
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRI-HTGEKPFEC 349

Query: 185 PAPAKKMVEDGQ--SGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
               K      Q  +        + F C  C K F  K  L  H   H+ + P  C  C 
Sbjct: 350 RECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECR 409

Query: 242 VTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSCRK----FP 295
             FR    L+ H      + P   +  G+ F Q +  I       G   F C K    F 
Sbjct: 410 KAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFS 469

Query: 296 RISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPG 355
           R SQ       +R  + +  + C  C KAF    SL  H++ H       EKP      G
Sbjct: 470 RKSQL---VRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTG-----EKPYVCSECG 521

Query: 356 DALDQKGFLALLGLQHT 372
            A  QK  L      HT
Sbjct: 522 KAFCQKSHLISHQRTHT 538



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 81/312 (25%), Positives = 122/312 (39%), Gaps = 37/312 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C K  + +  L  H   H   TG     CS CGK+ S  S L RH
Sbjct: 421 HQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRH 477

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+PY+C+ CG++F+   ++  H +IH  +     +    +  ++  L S ++ +
Sbjct: 478 QRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQR-T 536

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKK--ADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           H  E   E     K   E       ++    ++ + C  C K F  K  L TH   H+ +
Sbjct: 537 HTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGE 596

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            P  C +C   F     L+RH       L      +P+  N                 CR
Sbjct: 597 KPYECSLCRKAFFEKSELIRH-------LRTHTGEKPYECNE----------------CR 633

Query: 293 KFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATP 352
           K  R   +    N +R  + +  F C  C KAF     L  H++TH       EKP    
Sbjct: 634 KAFREKSSLI--NHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTG-----EKPYGCS 686

Query: 353 LPGDALDQKGFL 364
               A  QK  L
Sbjct: 687 ECRKAFSQKSQL 698



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 57/185 (30%), Positives = 73/185 (39%), Gaps = 45/185 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y CR C + F+    L  H R H G  PY+C++C     +K+ LIRHLRTH+GE+PY C 
Sbjct: 571 YECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECN 630

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++   H R   +    K  E                       C  CG+  
Sbjct: 631 ECRKAFREKSSLINHQR---IHTGEKPFE-----------------------CSECGKAF 664

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+ C EC  AF+ K 
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 804 NCIHH 808
             I+H
Sbjct: 725 QLINH 729



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 82/329 (24%), Positives = 127/329 (38%), Gaps = 47/329 (14%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +  T   +  YNC  C K  + + QLT H R H   TG   + C  CGK+ S  S L  H
Sbjct: 253 HHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH---TGEKPYECGECGKAFSRKSHLISH 309

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDP---------------------NSA 154
              H+GE+PY C  CG++F+   N+  H +IH  +                       + 
Sbjct: 310 WRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTH 369

Query: 155 TATAP--PSPLKRRRLSSKRKLSHDAESEREDP---APAKKMVEDGQSGDLEKKA---DE 206
           T T P   S  ++        + H      E P   +  +K   +  S    ++    ++
Sbjct: 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEK 429

Query: 207 VFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA 265
              C  C K F  K  L +H  TH+ + P  C  C   F     L+RH      + P + 
Sbjct: 430 PHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYEC 489

Query: 266 M--GRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNL----RRCISEQHRFVCD 319
              G+ F +            G   + C +     +A+C+ +     +R  + +  + C 
Sbjct: 490 SECGKAFSEKLSLTNHQRIHTGEKPYVCSE---CGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 320 TCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C KAF    SLA H++TH       EKP
Sbjct: 547 ECGKAFGEKSSLATHQRTHTG-----EKP 570



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 59/196 (30%), Positives = 77/196 (39%), Gaps = 48/196 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY+C  C    + K+ LI H RTH+GE+PY C 
Sbjct: 263 YNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCN 322

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+N   H R   +    K  E                       CR CG+  
Sbjct: 323 ECGRAFSEKSNLINHQR---IHTGEKPFE-----------------------CRECGKAF 356

Query: 763 KHYRALRIHMRTHCGRGLGGG-------------------HKGRKPFECKECSAAFAAKR 803
                L  H RTH G    G                    H G KP+EC EC  AF  + 
Sbjct: 357 SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERS 416

Query: 804 NCIHHILKQHLHVPEQ 819
           + I+H   Q  H  E+
Sbjct: 417 SLINH---QRTHTGEK 429



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 22/183 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  PY+C  C+   + K+ L  H R H+GE+PY C 
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECS 602

Query: 703 ICHYPFTVKANCERHLRKK------HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
           +C   F  K+   RHLR             RK   +    ++       +        C 
Sbjct: 603 LCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGE----KPFECS 658

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L  H RT         H G KP+ C EC  AF+ K   ++H   Q +H 
Sbjct: 659 ECGKAFSRKSHLIPHQRT---------HTGEKPYGCSECRKAFSQKSQLVNH---QRIHT 706

Query: 817 PEQ 819
            E+
Sbjct: 707 GEK 709



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 58/182 (31%), Positives = 74/182 (40%), Gaps = 14/182 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H G  PY C+ C      K+ LI H RTH+GE+PY C 
Sbjct: 487 YECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECS 546

Query: 703 ICHYPFTVKANCERHLRKK--HLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   F  K++   H R          +D EK     S                C LC +
Sbjct: 547 ECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD 820
                  L  H+RT         H G KP+EC EC  AF  K + I+H   Q +H  E+ 
Sbjct: 607 AFFEKSELIRHLRT---------HTGEKPYECNECRKAFREKSSLINH---QRIHTGEKP 654

Query: 821 IE 822
            E
Sbjct: 655 FE 656



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 95/387 (24%), Positives = 141/387 (36%), Gaps = 75/387 (19%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   SSL  H  THTG+KP  C +C   FS KS+   HQ+   G       + 
Sbjct: 405  CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464

Query: 1308 GLIPQSKESDVGSHDSTDSQSD----AETAAAAGEVLDLTSRDREQPSEGATELRQVAGD 1363
            G    S++S +  H  T +       +E   A  E L LT+  R    E      +  G 
Sbjct: 465  GKA-FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSE-CGK 522

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
            A  +++        H   H R  +H  E+ +   E  G A G +   +++Q         
Sbjct: 523  AFCQKS--------HLISHQR--THTGEKPYECSEC-GKAFGEKSSLATHQRTH------ 565

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD------ 1477
                               + E+   C  C K+F     L+ H++ H  ++P +      
Sbjct: 566  -------------------TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRK 606

Query: 1478 ---EKGDGA----STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPS 1530
               EK +      +   E P    E  +   E  + +       GE P E          
Sbjct: 607  AFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFEC--------- 657

Query: 1531 DGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHT 1590
               S   K  S KS      +T +         ++   CS C K F     L  H R HT
Sbjct: 658  ---SECGKAFSRKSHLIPHQRTHT--------GEKPYGCSECRKAFSQKSQLVNHQRIHT 706

Query: 1591 GERPYKCQTCERTFTLKHSLVRHQRIH 1617
            GE+PY+C  C + F+ K  L+ HQR H
Sbjct: 707  GEKPYRCIECGKAFSQKSQLINHQRTH 733



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 60/202 (29%), Positives = 84/202 (41%), Gaps = 26/202 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  P+ C  C    + K+ LI H  TH+GE+P+IC 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKN---IEYVSSSAAELVDAFCAPDTVCRLCG 759
            C   F+ K+   RH R    +   +  E      E +S +  + +     P  VC  CG
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP-YVCSECG 521

Query: 760 EDLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAAFA 800
           +       L  H RTH          CG+  G           H G KP+EC++C  AF+
Sbjct: 522 KAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFS 581

Query: 801 AKRNCIHHILKQHLHVPEQDIE 822
            K     H   Q +H  E+  E
Sbjct: 582 QKSQLNTH---QRIHTGEKPYE 600



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 49/172 (28%), Positives = 71/172 (41%), Gaps = 19/172 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L +H R+H G  PY CN C    ++K+ LI H R H+GE+P+ C+
Sbjct: 291 YECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECR 350

Query: 703 ICHYPFTVKANCERHLRKKH------LKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F+ K+    H R             RK   +  E +        +        C 
Sbjct: 351 ECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEK----PYECS 406

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            C +  +   +L  H RTH G          KP  C +C  AF+ K + I H
Sbjct: 407 ECRKAFRERSSLINHQRTHTGE---------KPHGCIQCGKAFSQKSHLISH 449



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 96/441 (21%), Positives = 152/441 (34%), Gaps = 70/441 (15%)

Query: 1196 FLQTAEDNTQDEVAGAPADHH----------GPSDEEQGSPPEDKLLRAKRNSYTNCLQK 1245
            F+   + N++ ++ G    HH          G ++ +  +  ++  L +K       L+ 
Sbjct: 120  FVPLRKSNSEGDLDGLILKHHLDLLIPKGDYGKAESDDFNVFDNFFLHSKPEDTDTWLKY 179

Query: 1246 ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLR-----KHGVT 1300
              C      +  +  +  H     G+K + C +C   FS K +  +HQ R       G  
Sbjct: 180  YDCDKYKESYKKSQIIIYHR-NRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCG 238

Query: 1301 TCSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQV 1360
             C        PQ  +S   +H  T +       +  G+          Q S+  +  R  
Sbjct: 239  NC----GKTFPQ--KSQFITHHRTHTGEKPYNCSQCGKAF-------SQKSQLTSHQRTH 285

Query: 1361 AGDAPVEQATAETASPVHREEH--GRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDL 1418
             G+ P E    E      R+ H      +H  E+ +G  E  G A   + +  ++Q +  
Sbjct: 286  TGEKPYE--CGECGKAFSRKSHLISHWRTHTGEKPYGCNE-CGRAFSEKSNLINHQRIH- 341

Query: 1419 DFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDE 1478
                                    + E+   C  CGK+F     L  H + H   +P   
Sbjct: 342  ------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFG- 376

Query: 1479 KGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPA--EKLAEETEGPSDGESAA 1536
              D      E  +    Q     E P E  E      E  +        T     G    
Sbjct: 377  CSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCIQC 436

Query: 1537 EKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYK 1596
             K  S+KS       T +         ++  +CS C K F     L RH R+HTGE+PY+
Sbjct: 437  GKAFSQKSHLISHQMTHT--------GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYE 488

Query: 1597 CQTCERTFTLKHSLVRHQRIH 1617
            C  C + F+ K SL  HQRIH
Sbjct: 489  CSECGKAFSEKLSLTNHQRIH 509



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 38/181 (20%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           LY C  C + F+    L  H   H+    + C  C      K+  I H RTH+GE+PY C
Sbjct: 206 LYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNC 265

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGED 761
             C   F+ K+    H R           EK  E                   C  CG+ 
Sbjct: 266 SQCGKAFSQKSQLTSHQR-------THTGEKPYE-------------------CGECGKA 299

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDI 821
                 L  H RT         H G KP+ C EC  AF+ K N I+H   Q +H  E+  
Sbjct: 300 FSRKSHLISHWRT---------HTGEKPYGCNECGRAFSEKSNLINH---QRIHTGEKPF 347

Query: 822 E 822
           E
Sbjct: 348 E 348



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 28/82 (34%), Positives = 41/82 (50%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PY C+ C    + K+ L+ H R H+GE+PY C 
Sbjct: 655 FECSECGKAFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCI 714

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F+ K+    H R   +K
Sbjct: 715 ECGKAFSQKSQLINHQRTHTVK 736



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 33/110 (30%), Positives = 41/110 (37%), Gaps = 5/110 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK 1628
            C  C K F        H R+HTGE+PY C  C + F+ K  L  HQR H         G+
Sbjct: 237  CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTH-TGEKPYECGE 295

Query: 1629 DSDKEERGEEDSENESTHSGNNAVSENEAELA----PNASNHMAVTRSRK 1674
                  R      +  TH+G      NE   A     N  NH  +    K
Sbjct: 296  CGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEK 345



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
            C  C + F   S L  H   HTG+KP+ C +C   FS KS    HQ R H V
Sbjct: 685  CSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQ-RTHTV 735



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 34/140 (24%), Positives = 50/140 (35%), Gaps = 38/140 (27%)

Query: 683 KAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAA 742
           K+ +I + R   GE+ Y C  C   F+ K +  +H + +H++    DI            
Sbjct: 191 KSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIR----DIAFG--------- 236

Query: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802
                       C  CG+          H RTH G          KP+ C +C  AF+ K
Sbjct: 237 ------------CGNCGKTFPQKSQFITHHRTHTGE---------KPYNCSQCGKAFSQK 275

Query: 803 RNCIHHILKQHLHVPEQDIE 822
                H   Q  H  E+  E
Sbjct: 276 SQLTSH---QRTHTGEKPYE 292


>gi|190610025 zinc finger protein 93 homolog [Homo sapiens]
          Length = 738

 Score =  110 bits (276), Expect = 9e-24
 Identities = 80/292 (27%), Positives = 125/292 (42%), Gaps = 21/292 (7%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K  +    L +H R H   TG   + C +CGK  +  S L  H  +H+GE+PY
Sbjct: 375 YRCDSCGKGFSRSTDLNIHCRVH---TGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPY 431

Query: 126 KCTVCGQSFTTNGNMHRHMKIH-EKDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           KC  CG+ F+ + N+H H ++H E+ P           L     S +R  + +   + E+
Sbjct: 432 KCGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEE 491

Query: 185 PAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVT 243
                      QS       ++ F C VC K F      + H   H+ + P +C++C   
Sbjct: 492 CGKGFSSASSFQSHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKR 551

Query: 244 FRTHRGLLRHNALVHKQLPR--DAMGRPF-----IQNNPSIPAGFHDLGFTDFSCRKFPR 296
           F     L  H  +   + P   +  G+ F     +Q + S+  G  +  F   +C+K  R
Sbjct: 552 FNWSLNLHNHQRVHTGEKPYKCEECGKGFSQASNLQAHQSVHTG--EKPFKCDACQK--R 607

Query: 297 ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            SQA      +R  + +  + CDTC KAF    +L +H+  H       EKP
Sbjct: 608 FSQASHLQAHQRVHTGEKPYKCDTCGKAFSQRSNLQVHQIIHTG-----EKP 654



 Score =  101 bits (252), Expect = 6e-21
 Identities = 71/293 (24%), Positives = 120/293 (40%), Gaps = 10/293 (3%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q    E+  Y C  C K  +    L  H R H   TG   + C  CGK  SSASS   H
Sbjct: 449 HQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVH---TGEKPYKCEECGKGFSSASSFQSH 505

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRKL 174
             VH+GE+P++C VCG+ F+ +     H ++H  + P                 + +R  
Sbjct: 506 QRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQRVH 565

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DN 233
           + +   + E+         + Q+       ++ F C  C K F     L+ H   H+ + 
Sbjct: 566 TGEKPYKCEECGKGFSQASNLQAHQSVHTGEKPFKCDACQKRFSQASHLQAHQRVHTGEK 625

Query: 234 PLRCDICCVTFRTHRGLLRHNALVH---KQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFS 290
           P +CD C   F + R  L+ + ++H   K    +  G+ F  +           G   ++
Sbjct: 626 PYKCDTCGKAF-SQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPYT 684

Query: 291 CRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAAD 342
           C++  +  SQA      +R  + +  ++CD C K F     L  H++ H   +
Sbjct: 685 CQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQRVHTGGN 737



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 75/314 (23%), Positives = 122/314 (38%), Gaps = 13/314 (4%)

Query: 87  QHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKI 146
           Q +  TG   + C  CGK  S +S+L  H  VH+GE+PY C  CG+SF  + +++ H+ I
Sbjct: 309 QQSVRTGKKRYWCHECGKGFSQSSNLQTHQRVHTGEKPYTCHECGKSFNQSSHLYAHLPI 368

Query: 147 HEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDG--QSGDLEKKA 204
           H  +      +      +   L+   ++ H  E   +     K   +    Q+ +     
Sbjct: 369 HTGEKPYRCDSCGKGFSRSTDLNIHCRV-HTGEKPYKCEVCGKGFTQRSHLQAHERIHTG 427

Query: 205 DEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPR 263
           ++ + C  C K F C   L TH   H+ + P +CD C   F     L  H  +   + P 
Sbjct: 428 EKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPY 487

Query: 264 --DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDT 320
             +  G+ F   +          G   F C    +  SQ+      +R  + +  + C+ 
Sbjct: 488 KCEECGKGFSSASSFQSHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEV 547

Query: 321 CDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPA 380
           C K F    +L  H++ H       EKP      G    Q   L      HT + +P   
Sbjct: 548 CGKRFNWSLNLHNHQRVHTG-----EKPYKCEECGKGFSQASNLQAHQSVHTGE-KPFKC 601

Query: 381 EEPLPDDNQAIQLQ 394
           +      +QA  LQ
Sbjct: 602 DACQKRFSQASHLQ 615



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 100/447 (22%), Positives = 156/447 (34%), Gaps = 65/447 (14%)

Query: 1211 APADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTG 1270
            A + H   +    G P +  +   K+  +        C  C + F  +S+LQ H   HTG
Sbjct: 292  ACSTHEKDTSYSSGIPVQQSVRTGKKRYW--------CHECGKGFSQSSNLQTHQRVHTG 343

Query: 1271 QKPFPCQKCDAFFSTKSNCERHQLRKHGVTT--CSLRRNGLIPQSKESDVGSHDSTDSQS 1328
            +KP+ C +C   F+  S+   H     G     C     G    S+ +D+  H    +  
Sbjct: 344  EKPYTCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGKGF---SRSTDLNIHCRVHTGE 400

Query: 1329 DAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE----------QATAETASPVH 1378
                    G+    T R   Q  E     R   G+ P +           +   T   VH
Sbjct: 401  KPYKCEVCGK--GFTQRSHLQAHE-----RIHTGEKPYKCGDCGKRFSCSSNLHTHQRVH 453

Query: 1379 REE------------------HGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---D 1417
             EE                  H     H  E+ +  EE  G    +     S+Q +   +
Sbjct: 454  TEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEEC-GKGFSSASSFQSHQRVHTGE 512

Query: 1418 LDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK- 1476
              F   +     ++           + E+   C+ CGK F +   L  H++ H  ++P  
Sbjct: 513  KPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQRVHTGEKPYK 572

Query: 1477 -DEKGDGASTAEE-GPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGES 1534
             +E G G S A       +    EKP +  A   +    A    A +     E P   ++
Sbjct: 573  CEECGKGFSQASNLQAHQSVHTGEKPFKCDA-CQKRFSQASHLQAHQRVHTGEKPYKCDT 631

Query: 1535 AAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERP 1594
               K  S++S+            +    +K  K C  C K F     L+ H R HTGE+P
Sbjct: 632  CG-KAFSQRSNLQVH-------QIIHTGEKPFK-CEECGKEFSWSAGLSAHQRVHTGEKP 682

Query: 1595 YKCQTCERTFTLKHSLVRHQRIHQKAR 1621
            Y CQ C + F+       HQR+H   R
Sbjct: 683  YTCQQCGKGFSQASHFHTHQRVHTGER 709



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 46/173 (26%), Positives = 72/173 (41%), Gaps = 16/173 (9%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ +   ++H R H G  P++CN+C    +  +    H R H+GE+PY C+
Sbjct: 487 YKCEECGKGFSSASSFQSHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCE 546

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
           +C   F    N   H R    +K  K   ++  K     S+  A            C  C
Sbjct: 547 VCGKRFNWSLNLHNHQRVHTGEKPYKC--EECGKGFSQASNLQAHQSVHTGEKPFKCDAC 604

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNC-IHHIL 810
            +       L+ H R          H G KP++C  C  AF+ + N  +H I+
Sbjct: 605 QKRFSQASHLQAHQRV---------HTGEKPYKCDTCGKAFSQRSNLQVHQII 648



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 47/169 (27%), Positives = 73/169 (43%), Gaps = 13/169 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ +  L+AH   H G  P++C+ C    +  + L  H R H+GE+PY C 
Sbjct: 571 YKCEECGKGFSQASNLQAHQSVHTGEKPFKCDACQKRFSQASHLQAHQRVHTGEKPYKCD 630

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSS---SAAELVDAFCAPDTVCRLCG 759
            C   F+ ++N + H      +   K  E   E+  S   SA + V     P T C+ CG
Sbjct: 631 TCGKAFSQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPYT-CQQCG 689

Query: 760 EDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           +          H R H G          +P+ C  C   F+ + + I+H
Sbjct: 690 KGFSQASHFHTHQRVHTGE---------RPYICDVCCKGFSQRSHLIYH 729



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 49/179 (27%), Positives = 75/179 (41%), Gaps = 14/179 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  L AH+  H G  PY+C+ C    +    L  H R H+GE+PY C+
Sbjct: 347 YTCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGKGFSRSTDLNIHCRVHTGEKPYKCE 406

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
           +C   FT +++ + H R    +   K  +    +  SS           +    C  CG+
Sbjct: 407 VCGKGFTQRSHLQAHERIHTGEKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGK 466

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
                  L  H R          H G KP++C+EC   F++  +   H   Q +H  E+
Sbjct: 467 CFSLSFNLHSHQRV---------HTGEKPYKCEECGKGFSSASSFQSH---QRVHTGEK 513



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 45/177 (25%), Positives = 68/177 (38%), Gaps = 38/177 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ S  L +H R H G  PY+C  C    +  ++   H R H+GE+P+ C 
Sbjct: 459 YKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASSFQSHQRVHTGEKPFRCN 518

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
           +C   F+  +  + H R    +   K                          C +CG+  
Sbjct: 519 VCGKGFSQSSYFQAHQRVHTGEKPYK--------------------------CEVCGKRF 552

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
                L  H R          H G KP++C+EC   F+   N   H   Q +H  E+
Sbjct: 553 NWSLNLHNHQRV---------HTGEKPYKCEECGKGFSQASNLQAH---QSVHTGEK 597



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 28/77 (36%), Positives = 40/77 (51%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F++S  L AH R H G  PY C  C    +  +    H R H+GERPYIC 
Sbjct: 655 FKCEECGKEFSWSAGLSAHQRVHTGEKPYTCQQCGKGFSQASHFHTHQRVHTGERPYICD 714

Query: 703 ICHYPFTVKANCERHLR 719
           +C   F+ +++   H R
Sbjct: 715 VCCKGFSQRSHLIYHQR 731



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 64/267 (23%), Positives = 106/267 (39%), Gaps = 31/267 (11%)

Query: 97  HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH--EKDPNSA 154
           HS S CGK     S L +   +H+G++ Y+   C ++F  + ++  H ++H  +K P  +
Sbjct: 236 HSNSDCGKDTLKVSPLTQRS-IHTGQKTYQGNECEEAFNDSSSLELHKQVHLGKKSPACS 294

Query: 155 TATAPPS-----PLKRR-RLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVF 208
           T     S     P+++  R   KR   H+                + Q+       ++ +
Sbjct: 295 THEKDTSYSSGIPVQQSVRTGKKRYWCHEC-------GKGFSQSSNLQTHQRVHTGEKPY 347

Query: 209 HCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVH---KQLPRD 264
            C  C K F     L  H+  H+ + P RCD C   F     L  H   VH   K    +
Sbjct: 348 TCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGKGFSRSTDLNIH-CRVHTGEKPYKCE 406

Query: 265 AMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNL---RRCISEQHRFVCDTC 321
             G+ F Q +          G   + C    +  +  C +NL   +R  +E+  + CD C
Sbjct: 407 VCGKGFTQRSHLQAHERIHTGEKPYKCGDCGK--RFSCSSNLHTHQRVHTEEKPYKCDEC 464

Query: 322 DKAFPMLCSLALHKQTHVAADQGQEKP 348
            K F +  +L  H++ H       EKP
Sbjct: 465 GKCFSLSFNLHSHQRVHTG-----EKP 486



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 76/346 (21%), Positives = 127/346 (36%), Gaps = 32/346 (9%)

Query: 63  KSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGE 122
           + +Y    CE+       L +H + H    G    +CS   K  S +S +     V +G+
Sbjct: 260 QKTYQGNECEEAFNDSSSLELHKQVH---LGKKSPACSTHEKDTSYSSGIPVQQSVRTGK 316

Query: 123 RPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESER 182
           + Y C  CG+ F+ + N+  H ++H  +          S  +   L +   + H  E   
Sbjct: 317 KRYWCHECGKGFSQSSNLQTHQRVHTGEKPYTCHECGKSFNQSSHLYAHLPI-HTGEKPY 375

Query: 183 EDPAPAKKMVEDGQSGDLE-----KKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLR 236
              +  K      +S DL         ++ + C VC K F  +  L+ H   H+ + P +
Sbjct: 376 RCDSCGKGF---SRSTDLNIHCRVHTGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPYK 432

Query: 237 CDICCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHD-----LGFTDF 289
           C  C   F     L  H  +  ++ P   D  G+ F     S+    H       G   +
Sbjct: 433 CGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGKCF-----SLSFNLHSHQRVHTGEKPY 487

Query: 290 SCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C +  +  S A    + +R  + +  F C+ C K F        H++ H       EKP
Sbjct: 488 KCEECGKGFSSASSFQSHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTG-----EKP 542

Query: 349 QATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQ 394
               + G   +    L      HT + +P   EE     +QA  LQ
Sbjct: 543 YKCEVCGKRFNWSLNLHNHQRVHTGE-KPYKCEECGKGFSQASNLQ 587



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 53/227 (23%), Positives = 84/227 (37%), Gaps = 44/227 (19%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQPAPEQEEKPPE 1502
            E+   C  CGK F     L  H++ H  ++P   DE G   S +         Q     E
Sbjct: 428  EKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHS---HQRVHTGE 484

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKA 1562
             P +  E   G                    SA+  +S ++    +KP            
Sbjct: 485  KPYKCEECGKGFS------------------SASSFQSHQRVHTGEKPFR---------- 516

Query: 1563 DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKA 1620
                  C+VC K F        H R HTGE+PYKC+ C + F    +L  HQR+H  +K 
Sbjct: 517  ------CNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQRVHTGEKP 570

Query: 1621 RHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHM 1667
               +  GK   +    +    ++S H+G      +  +   + ++H+
Sbjct: 571  YKCEECGKGFSQASNLQ---AHQSVHTGEKPFKCDACQKRFSQASHL 614



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 24/56 (42%), Positives = 31/56 (55%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAK 1624
            C VC K F     L  H R HTGE+PYKC  C + F+   +L  HQR+H + +  K
Sbjct: 405  CEVCGKGFTQRSHLQAHERIHTGEKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYK 460



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 46/193 (23%), Positives = 72/193 (37%), Gaps = 27/193 (13%)

Query: 632 GKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLR 691
           GKK+PA       C    +  ++S  +        G   Y C+ C    +  + L  H R
Sbjct: 287 GKKSPA-------CSTHEKDTSYSSGIPVQQSVRTGKKRYWCHECGKGFSQSSNLQTHQR 339

Query: 692 THSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAP 751
            H+GE+PY C  C   F   ++   HL    +    K    +      S +  ++  C  
Sbjct: 340 VHTGEKPYTCHECGKSFNQSSHLYAHL---PIHTGEKPYRCDSCGKGFSRSTDLNIHCRV 396

Query: 752 DT-----VCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCI 806
            T      C +CG+       L+ H R          H G KP++C +C   F+   N  
Sbjct: 397 HTGEKPYKCEVCGKGFTQRSHLQAHERI---------HTGEKPYKCGDCGKRFSCSSNLH 447

Query: 807 HHILKQHLHVPEQ 819
            H   Q +H  E+
Sbjct: 448 TH---QRVHTEEK 457



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 607 PLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHL 666
           P   +A  K+      L+A      G+K        Y C  C + F+    L+ H   H 
Sbjct: 598 PFKCDACQKRFSQASHLQAHQRVHTGEKP-------YKCDTCGKAFSQRSNLQVHQIIHT 650

Query: 667 GISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLR 719
           G  P++C  C    +  A L  H R H+GE+PY C+ C   F+  ++   H R
Sbjct: 651 GEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPYTCQQCGKGFSQASHFHTHQR 703



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 1538 KRSSEKSDDDKKPKTDS--PKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPY 1595
            K+S   S  +K     S  P   + +  K++  C  C K F    +L  H R HTGE+PY
Sbjct: 288  KKSPACSTHEKDTSYSSGIPVQQSVRTGKKRYWCHECGKGFSQSSNLQTHQRVHTGEKPY 347

Query: 1596 KCQTCERTFTLKHSLVRHQRIH 1617
             C  C ++F     L  H  IH
Sbjct: 348  TCHECGKSFNQSSHLYAHLPIH 369



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 18/53 (33%), Positives = 28/53 (52%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSG 695
           Y C+ C + F+ +     H R H G  PY C++C    + ++ LI H R H+G
Sbjct: 683 YTCQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQRVHTG 735



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 18/47 (38%), Positives = 24/47 (51%)

Query: 1247 TCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            TC  C + F  AS    H   HTG++P+ C  C   FS +S+   HQ
Sbjct: 684  TCQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQ 730



 Score = 34.7 bits (78), Expect = 0.83
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 5/71 (7%)

Query: 1564 KRKKVCSV--CNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QK 1619
            KR KV S   C K    +  LT+    HTG++ Y+   CE  F    SL  H+++H  +K
Sbjct: 231  KRDKVHSNSDCGKDTLKVSPLTQRS-IHTGQKTYQGNECEEAFNDSSSLELHKQVHLGKK 289

Query: 1620 ARHAKHHGKDS 1630
            +     H KD+
Sbjct: 290  SPACSTHEKDT 300


>gi|122937229 zinc finger protein 629 [Homo sapiens]
          Length = 869

 Score =  110 bits (276), Expect = 9e-24
 Identities = 82/297 (27%), Positives = 123/297 (41%), Gaps = 22/297 (7%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++Q T   +  Y C  CEK  T    L  H R H   TG   + C  C ++   +S L +
Sbjct: 223 QHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSH---TGEKPYKCGECRRAFYRSSDLIQ 279

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKL 174
           H   H+GE+PYKC  CG+ F  N N+ +H KIH  +          S ++   L+  ++ 
Sbjct: 280 HQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQR- 338

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEKK-----ADEVFHCPVCFKEFVCKYGLETHMET 229
           +H  E   E     K     G S  L K       ++ F CPVC K F     L  H  T
Sbjct: 339 THTGEKPYECLECGKSF---GHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRT 395

Query: 230 HS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGF 286
           H+ + P +C  C  +F     L+ H  +   + P      G+ FI ++  I       G 
Sbjct: 396 HTGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGE 455

Query: 287 TDFSC----RKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHV 339
             + C    + F R S        RR  + +  + C  C K+F    +L  H +TH+
Sbjct: 456 KPYKCSDCGKSFIRSSHL---IQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHM 509



 Score =  110 bits (274), Expect = 2e-23
 Identities = 153/707 (21%), Positives = 241/707 (34%), Gaps = 141/707 (19%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           R+Q     +    C  C K  T    L  H R H   TG   + C  CGK  S +S+L +
Sbjct: 167 RHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTH---TGEKPYKCPDCGKCFSWSSNLVQ 223

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKL 174
           H   H+GE+PYKCT C ++FT + N+ +H + H  +          +  +   L  + + 
Sbjct: 224 HQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDL-IQHQA 282

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEK-----KADEVFHCPVCFKEFVCKYGLETHMET 229
           +H  E   + P   K+    GQ+ +L K       ++ + C  C K F+    L  H  T
Sbjct: 283 THTGEKPYKCPECGKRF---GQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRT 339

Query: 230 HS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGF--HDLGF 286
           H+ + P  C  C  +F     L++H       L  D    P      ++ A    H    
Sbjct: 340 HTGEKPYECLECGKSFGHSSTLIKHQ---RTHLREDPFKCPVCGKTFTLSATLLRHQRTH 396

Query: 287 TDFSCRKFPRISQAWCET----NLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAAD 342
           T     K P   +++  +    N +R    +  ++C  C K+F M  +L  H++ H    
Sbjct: 397 TGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTG-- 454

Query: 343 QGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQT-LKCQLP 401
              EKP      G +  +   L      HT + +P    E     +Q+  L T ++  + 
Sbjct: 455 ---EKPYKCSDCGKSFIRSSHLIQHRRTHTGE-KPYKCPECGKSFSQSSNLITHVRTHMD 510

Query: 402 QDPGCTNLLSLSPFEAASLGGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISG 461
           +     NL   S    A                  L     ++  +I        +   G
Sbjct: 511 E-----NLFVCSDCGKA-----------------FLEAHELEQHRVIHERGKTPARRAQG 548

Query: 462 ESAIELADIQQILKMAASAPPQISLP-----------------PFSKAPAAPLQAIFKHM 504
           +S + L D   +L     A P   L                     + P      +  H 
Sbjct: 549 DSLLGLGD-PSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHA 607

Query: 505 PPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQ 564
            P KP  L +PR     ++ P     +  +PG         PLK  +G    +    LL 
Sbjct: 608 AP-KPPQLRSPRLPFRGNSYPGAAEGRAEAPG--------QPLKPPEGQEGFSQRRGLLS 658

Query: 565 SKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDSIIEALLPLSMEAKIKQEITEGELK 624
           SK+    H                                   L     ++ ++T G  K
Sbjct: 659 SKTYICSHCGESF------------------------------LDRSVLLQHQLTHGNEK 688

Query: 625 AFM-------TAPGGKKTPAMRKVLYPCRFCNQVFAF----------------------- 654
            F+          G   +P +    + C  C Q F                         
Sbjct: 689 PFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPEL 748

Query: 655 ---SGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
              S VL  H+RS LG  PY+C+ C     D+ AL RH  TH+ E+P
Sbjct: 749 GKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKP 795



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 65/238 (27%), Positives = 95/238 (39%), Gaps = 31/238 (13%)

Query: 20  MMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQH 79
           + S+ ++  + T  G  P       K  G +    ++Q T   +  + CP+C K  T   
Sbjct: 328 IQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSA 387

Query: 80  QLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGN 139
            L  H R H   TG   + C  CGKS S +S+L  H  +H GERPY C  CG+SF  +  
Sbjct: 388 TLLRHQRTH---TGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSST 444

Query: 140 MHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGD 199
           + RH +IH  +     +    S ++   L   R+ +H  E                    
Sbjct: 445 LIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRR-THTGE-------------------- 483

Query: 200 LEKKADEVFHCPVCFKEFVCKYGLETHMETHSD-NPLRCDICCVTFRTHRGLLRHNAL 256
                 + + CP C K F     L TH+ TH D N   C  C   F     L +H  +
Sbjct: 484 ------KPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVI 535



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 91/361 (25%), Positives = 132/361 (36%), Gaps = 79/361 (21%)

Query: 29  KVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQH 88
           + T  G  P       K  G N    ++Q+    +  Y C  C K      +LT H R H
Sbjct: 281 QATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTH 340

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE 148
              TG   + C  CGKS   +S+L +H   H  E P+KC VCG++FT +  + RH + H 
Sbjct: 341 ---TGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTH- 396

Query: 149 KDPNSATATAP---PSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKAD 205
                 T   P   P   K   +SS   ++H      E P                    
Sbjct: 397 ------TGERPYKCPECGKSFSVSS-NLINHQRIHRGERP-------------------- 429

Query: 206 EVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRD 264
             + C  C K F+    L  H   H+ + P +C  C  +F     L++H      + P  
Sbjct: 430 --YICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYK 487

Query: 265 A--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCD 322
               G+ F Q++  I                          T++R  + E + FVC  C 
Sbjct: 488 CPECGKSFSQSSNLI--------------------------THVRTHMDE-NLFVCSDCG 520

Query: 323 KAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEE 382
           KAF     L  H+  H   ++G  K  A    GD        +LLGL     + P P  +
Sbjct: 521 KAFLEAHELEQHRVIH---ERG--KTPARRAQGD--------SLLGLGDPSLLTPPPGAK 567

Query: 383 P 383
           P
Sbjct: 568 P 568



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 52/169 (30%), Positives = 72/169 (42%), Gaps = 11/169 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  L  H R+HL   P++C +C       A L+RH RTH+GERPY C 
Sbjct: 346 YECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCP 405

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F+V +N   H R    +      +    ++ SS           +    C  CG+
Sbjct: 406 ECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGK 465

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHI 809
                  L  H RT         H G KP++C EC  +F+   N I H+
Sbjct: 466 SFIRSSHLIQHRRT---------HTGEKPYKCPECGKSFSQSSNLITHV 505



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 56/198 (28%), Positives = 79/198 (39%), Gaps = 24/198 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  L  H RSH G  PY+C  C       + LI+H  TH+GE+PY C 
Sbjct: 234 YKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCP 293

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F    N  +H +    +   +  E    ++ SS           +    C  CG+
Sbjct: 294 ECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGK 353

Query: 761 DLKHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAFAA 801
              H   L  H RTH          CG+              H G +P++C EC  +F+ 
Sbjct: 354 SFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSV 413

Query: 802 KRNCIHHILKQHLHVPEQ 819
             N I+H   Q +H  E+
Sbjct: 414 SSNLINH---QRIHRGER 428



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 57/213 (26%), Positives = 90/213 (42%), Gaps = 14/213 (6%)

Query: 1439 GGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEE 1498
            G  A  E+   C+ CGKSF     L RH++ H  + P      G S  +        Q  
Sbjct: 141  GRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSS-HLVQHQRT 199

Query: 1499 KPPETPAEVVESAPGAGEAPA-EKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKS 1557
               E P +     P  G+  +      + +    GE   +    EK+       T+  K 
Sbjct: 200  HTGEKPYK----CPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQS---TNLIKH 252

Query: 1558 VASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
              S   ++   C  C + F+   DL +H  +HTGE+PYKC  C + F   H+L++HQ+IH
Sbjct: 253  QRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIH 312

Query: 1618 --QKARHAKHHGKDSDKEERGEEDSENESTHSG 1648
              +K       GK      +  E ++++ TH+G
Sbjct: 313  AGEKPYRCTECGKSF---IQSSELTQHQRTHTG 342



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 55/199 (27%), Positives = 78/199 (39%), Gaps = 32/199 (16%)

Query: 645 CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKIC 704
           C  C + F  S  L  H R+H G  PY+C  C    +  + L++H RTH+GE+PY C  C
Sbjct: 180 CSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTEC 239

Query: 705 HYPFTVKANCERHLR----KKHLKA--TRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
              FT   N  +H R    +K  K    R+   ++ + +   A    +        C  C
Sbjct: 240 EKAFTQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGE----KPYKCPEC 295

Query: 759 GEDLKHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAF 799
           G+       L  H + H          CG+              H G KP+EC EC  +F
Sbjct: 296 GKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSF 355

Query: 800 AAKRNCIHHILKQHLHVPE 818
                 I H   Q  H+ E
Sbjct: 356 GHSSTLIKH---QRTHLRE 371



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 103/456 (22%), Positives = 158/456 (34%), Gaps = 88/456 (19%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F  +S+L RH   HTG+KP+ C  C   F   S+  +H+    G         
Sbjct: 432  CADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPEC 491

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQP----SEGATELRQVAGD 1363
            G    S+ S++ +H  T    +    +  G+   L + + EQ       G T  R+  GD
Sbjct: 492  GK-SFSQSSNLITHVRTHMDENLFVCSDCGKAF-LEAHELEQHRVIHERGKTPARRAQGD 549

Query: 1364 A------PVEQATAETASPVHREEHGRGESHEP-----EEEHGTEESTGDADGAEEDASS 1412
            +      P        A P      G+G + E      +  H  E    +ADG    A+ 
Sbjct: 550  SLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAP 609

Query: 1413 NQSLDLDFATKLMDFK------LAEGDGEA---------GAGGAASQEQKLA-----CDT 1452
                     +  + F+       AEG  EA         G  G + +   L+     C  
Sbjct: 610  KPP---QLRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSH 666

Query: 1453 CGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAP 1512
            CG+SF     L +H+  HG ++P     D      EG  P+P    KP + P        
Sbjct: 667  CGESFLDRSVLLQHQLTHGNEKPFLFP-DYRIGLGEGAGPSPFLSGKPFKCPE------- 718

Query: 1513 GAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVC 1572
                       +++ G S      +K  +      K P+     SV              
Sbjct: 719  ----------CKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSSV-------------- 754

Query: 1573 NKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK---- 1628
                     L  H+RS  G RPY+C  C  +F  + +L RHQ  H + +           
Sbjct: 755  ---------LLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKPPNPEDPPPEA 805

Query: 1629 ---DSDKEERGEEDSENESTHSGNNAVSENEAELAP 1661
                +D+E  GE  +  ES+  G     +   E  P
Sbjct: 806  VTLSTDQEGEGETPTPTESSSHGEGQNPKTLVEEKP 841



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 52/188 (27%), Positives = 73/188 (38%), Gaps = 18/188 (9%)

Query: 636 PAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSG 695
           PA  +  Y C  C + F+    L  H R H G  P  C+ C       + L++H RTH+G
Sbjct: 143 PAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTG 202

Query: 696 ERPYICKICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAP 751
           E+PY C  C   F+  +N  +H R    +K  K T  + EK     ++            
Sbjct: 203 EKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCT--ECEKAFTQSTNLIKHQRSHTGEK 260

Query: 752 DTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILK 811
              C  C         L  H  T         H G KP++C EC   F    N + H   
Sbjct: 261 PYKCGECRRAFYRSSDLIQHQAT---------HTGEKPYKCPECGKRFGQNHNLLKH--- 308

Query: 812 QHLHVPEQ 819
           Q +H  E+
Sbjct: 309 QKIHAGEK 316



 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 135/644 (20%), Positives = 210/644 (32%), Gaps = 105/644 (16%)

Query: 1128 EPPAPASSPEAASPTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLAT 1187
            EP      P+   P EQ P   + +          PR  S G ++       S E    +
Sbjct: 2    EPETALWGPDLQGP-EQSP-NDAHRGAESENEEESPRQESSGEEIIMGDPAQSPE----S 55

Query: 1188 TDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQK-- 1245
             D+ + S   ++++D +  +    P  H  P D +    P    +    + +T   +   
Sbjct: 56   KDSTEMS-LERSSQDPSVPQNPPTPLGHSNPLDHQIPLDPPAPEVVPTPSDWTKACEASW 114

Query: 1246 ----ITCPHCPRVFPWASSLQRHMLTHT---GQKPFPCQKCDAFFSTKSNCERHQLRKHG 1298
                +T  + P V P      R ++       +KP+ C +C   FS  S   RHQ    G
Sbjct: 115  QWGALTTWNSPPVVPANEPSLRELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTG 174

Query: 1299 V--TTCSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATE 1356
                TCS         ++ S +  H  T +          G+    +S   +        
Sbjct: 175  ERPNTCSECGKSF---TQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQ------ 225

Query: 1357 LRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL 1416
             R   G+ P +    E A            SH  E+ +   E    A     D   +Q+ 
Sbjct: 226  -RTHTGEKPYKCTECEKAFTQSTNLIKHQRSHTGEKPYKCGECRR-AFYRSSDLIQHQAT 283

Query: 1417 DLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK 1476
                                      + E+   C  CGK F     L +H+K H  ++P 
Sbjct: 284  H-------------------------TGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPY 318

Query: 1477 DEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAA 1536
                 G S  +   +    Q     E P E +E                  G S G S+ 
Sbjct: 319  RCTECGKSFIQSS-ELTQHQRTHTGEKPYECLEC-----------------GKSFGHSST 360

Query: 1537 ---EKRSSEKSDDDKKPKTDSPKSVASKADKRKKV--------CSVCNKRFWSLQDLTRH 1585
                +R+  + D  K P      ++++   + ++         C  C K F    +L  H
Sbjct: 361  LIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINH 420

Query: 1586 MRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHHGKDSDKEERGEEDSENE 1643
             R H GERPY C  C ++F +  +L+RHQRIH  +K       GK      R     ++ 
Sbjct: 421  QRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSF---IRSSHLIQHR 477

Query: 1644 STHSGNNAVSENE-AELAPNASNHMAVTRSRKEGLASATKDC-----------SHREEKV 1691
             TH+G       E  +    +SN +   R+  +       DC            HR    
Sbjct: 478  RTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHE 537

Query: 1692 TAGWPSEPGQGDLNPESPAALGQ-DLLEPRSKRPAHPILATADG 1734
                P+   QGD    S   LG   LL P      H  L    G
Sbjct: 538  RGKTPARRAQGD----SLLGLGDPSLLTPPPGAKPHKCLVCGKG 577



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 95/426 (22%), Positives = 143/426 (33%), Gaps = 109/426 (25%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTT--CS-- 1303
            CP C + F  +S+L  H   H G++P+ C  C   F   S   RHQ    G     CS  
Sbjct: 404  CPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDC 463

Query: 1304 ----LRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQ 1359
                +R + LI   +     +H         E   +  +  +L +  R    E       
Sbjct: 464  GKSFIRSSHLIQHRR-----THTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSD 518

Query: 1360 VAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLD 1419
              G A +E    E     HR  H RG++           + GD+                
Sbjct: 519  -CGKAFLEAHELEQ----HRVIHERGKTP-------ARRAQGDS---------------- 550

Query: 1420 FATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEK 1479
                     L  GD         ++  K  C  CGK F   G   +H++ H  + P  + 
Sbjct: 551  --------LLGLGDPSLLTPPPGAKPHK--CLVCGKGFNDEGIFMQHQRIHIGENPY-KN 599

Query: 1480 GDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKR 1539
             DG   A   P+P    + + P  P     S PGA E  AE   +  + P   E  +++R
Sbjct: 600  ADGL-IAHAAPKPP---QLRSPRLPFRG-NSYPGAAEGRAEAPGQPLKPPEGQEGFSQRR 654

Query: 1540 SSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPY---- 1595
                S                    +  +CS C + F     L +H  +H  E+P+    
Sbjct: 655  GLLSS--------------------KTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPD 694

Query: 1596 --------------------KCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKDSDKE-E 1634
                                KC  C+++F L   L+ HQ++H         GK S K  E
Sbjct: 695  YRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHA-------GGKSSQKSPE 747

Query: 1635 RGEEDS 1640
             G+  S
Sbjct: 748  LGKSSS 753



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 55/232 (23%), Positives = 95/232 (40%), Gaps = 17/232 (7%)

Query: 122 ERPYKCTVCGQSFTTNGNMHRHMKIHEKD-PNSATATAPPSPLKRRRLSSKRKLSHDAES 180
           E+PY C  CG+SF+    + RH +IH  + PN+ +            +  +R  +H  E 
Sbjct: 147 EKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQR--THTGEK 204

Query: 181 EREDPAPAK------KMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DN 233
             + P   K       +V+  ++   EK     + C  C K F     L  H  +H+ + 
Sbjct: 205 PYKCPDCGKCFSWSSNLVQHQRTHTGEKP----YKCTECEKAFTQSTNLIKHQRSHTGEK 260

Query: 234 PLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSC 291
           P +C  C   F     L++H A    + P      G+ F QN+  +       G   + C
Sbjct: 261 PYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRC 320

Query: 292 RKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAAD 342
            +  +   Q+   T  +R  + +  + C  C K+F    +L  H++TH+  D
Sbjct: 321 TECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLRED 372



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 41/165 (24%), Positives = 61/165 (36%), Gaps = 14/165 (8%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           + CP C++      +L +H + H    G +       GKS   +S L  H+    G RPY
Sbjct: 714 FKCPECKQSFGLSSELLLHQKVHAG--GKSSQKSPELGKS---SSVLLEHLRSPLGARPY 768

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           +C+ C  SF     + RH + H ++        PP  +          LS D E E E P
Sbjct: 769 RCSDCRASFLDRVALTRHQETHTQEKPPNPEDPPPEAV---------TLSTDQEGEGETP 819

Query: 186 APAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETH 230
            P +               ++ + CP C   F     L  H   H
Sbjct: 820 TPTESSSHGEGQNPKTLVEEKPYLCPECGAGFTEVAALLLHRSCH 864



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 51/211 (24%), Positives = 77/211 (36%), Gaps = 41/211 (19%)

Query: 529 NAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPG 588
           N  + + G I+ + P PP             +  L  +  + P AA      + RAE PG
Sbjct: 595 NPYKNADGLIAHAAPKPP----------QLRSPRLPFRGNSYPGAA------EGRAEAPG 638

Query: 589 QPEMKTQLEQDSIIEALLPLSMEAKI---------------KQEITEGELKAFM------ 627
           QP +K    Q+   +    LS +  I               + ++T G  K F+      
Sbjct: 639 QP-LKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRI 697

Query: 628 -TAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAAL 686
               G   +P +    + C  C Q F  S  L  H + H G    Q +    +    + L
Sbjct: 698 GLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKS--PELGKSSSVL 755

Query: 687 IRHLRTHSGERPYICKICHYPFTVKANCERH 717
           + HLR+  G RPY C  C   F  +    RH
Sbjct: 756 LEHLRSPLGARPYRCSDCRASFLDRVALTRH 786



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 38/148 (25%), Positives = 48/148 (32%), Gaps = 48/148 (32%)

Query: 691 RTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCA 750
           R    E+PYIC  C   F+  +   RH R                         +     
Sbjct: 142 RPAGAEKPYICNECGKSFSQWSKLLRHQR-------------------------IHTGER 176

Query: 751 PDTVCRLCGEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFE 791
           P+T C  CG+       L  H RTH          CG+              H G KP++
Sbjct: 177 PNT-CSECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYK 235

Query: 792 CKECSAAFAAKRNCIHHILKQHLHVPEQ 819
           C EC  AF    N I H   Q  H  E+
Sbjct: 236 CTECEKAFTQSTNLIKH---QRSHTGEK 260



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 82/391 (20%), Positives = 123/391 (31%), Gaps = 59/391 (15%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            CP C + F  +S+L  H+ TH  +  F C  C   F      E+H++      T + R  
Sbjct: 488  CPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRAQ 547

Query: 1308 G--LIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDR----EQPSEGATELRQVA 1361
            G  L+     S +                   +        R    E P + A  L  +A
Sbjct: 548  GDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGL--IA 605

Query: 1362 GDAPVEQATAETASPVHREEH-----GRGES-----HEPEEEHGTEESTGDADGAEEDAS 1411
              AP          P     +     GR E+       PE + G  +  G         S
Sbjct: 606  HAAPKPPQLRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICS 665

Query: 1412 SNQSLDLDFATKLMDFKLAEG--------DGEAGAGGAASQEQKLA-----CDTCGKSFK 1458
                  LD +  L+  +L  G        D   G G  A     L+     C  C +SF 
Sbjct: 666  HCGESFLDRSV-LLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFG 724

Query: 1459 FLGTLSRHRKAH--GRQEPKD-EKGDGASTAEE------GPQPAP---------EQEEKP 1500
                L  H+K H  G+   K  E G  +S   E      G +P           ++    
Sbjct: 725  LSSELLLHQKVHAGGKSSQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALT 784

Query: 1501 PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVAS 1560
                    E  P   + P E +   T+   +GE+     SS    + + PKT        
Sbjct: 785  RHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHG-EGQNPKT-------- 835

Query: 1561 KADKRKKVCSVCNKRFWSLQDLTRHMRSHTG 1591
              +++  +C  C   F  +  L  H   H G
Sbjct: 836  LVEEKPYLCPECGAGFTEVAALLLHRSCHPG 866



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 67/286 (23%), Positives = 94/286 (32%), Gaps = 55/286 (19%)

Query: 625 AFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKA 684
           + +T P G K        + C  C + F   G+   H R H+G +PY+    D + A  A
Sbjct: 558 SLLTPPPGAKP-------HKCLVCGKGFNDEGIFMQHQRIHIGENPYKN--ADGLIAHAA 608

Query: 685 ALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAEL 744
                LR  S   P+  +   YP   +   E   +       ++   +    +SS     
Sbjct: 609 PKPPQLR--SPRLPF--RGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTY-- 662

Query: 745 VDAFCAPDTVCRLCGEDLKHYRALRIHMRTH------------CGRGLGGGHK---GRKP 789
                    +C  CGE       L  H  TH             G G G G       KP
Sbjct: 663 ---------ICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKP 713

Query: 790 FECKECSAAFAAKRNCIHHILKQHLHV--------PEQDIESYVLAADGLGPAEAPAAEA 841
           F+C EC  +F      + H   Q +H         PE    S VL    L    +P    
Sbjct: 714 FKCPECKQSFGLSSELLLH---QKVHAGGKSSQKSPELGKSSSVL----LEHLRSPLGAR 766

Query: 842 SGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLE 887
             R  D   + L D   LT   E         P  PPP  V++  +
Sbjct: 767 PYRCSDCRASFL-DRVALTRHQETHTQEKPPNPEDPPPEAVTLSTD 811



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 42/222 (18%), Positives = 69/222 (31%), Gaps = 38/222 (17%)

Query: 1195 PFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRV 1254
            PF   +     +  A AP     P + ++G      LL +K            C HC   
Sbjct: 620  PFRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKT---------YICSHCGES 670

Query: 1255 FPWASSLQRHMLTHTGQKPF------------------------PCQKCDAFFSTKSNCE 1290
            F   S L +H LTH  +KPF                         C +C   F   S   
Sbjct: 671  FLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELL 730

Query: 1291 RHQLRKHGVTTCSL-----RRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSR 1345
             HQ    G  +        + + ++ +   S +G+     S   A             + 
Sbjct: 731  LHQKVHAGGKSSQKSPELGKSSSVLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETH 790

Query: 1346 DREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGES 1387
             +E+P        +    +  ++   ET +P     HG G++
Sbjct: 791  TQEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHGEGQN 832


>gi|134254457 zinc finger protein 665 [Homo sapiens]
          Length = 678

 Score =  108 bits (269), Expect = 6e-23
 Identities = 77/306 (25%), Positives = 129/306 (42%), Gaps = 15/306 (4%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K+ +   +LT H R H   TG   + C+ CGK+ +  S+L  H ++H+GE+PY
Sbjct: 178 YKCDECGKVFSQNSRLTSHKRIH---TGEKPYQCNKCGKAFTVRSNLTIHQVIHTGEKPY 234

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC  CG+ F+   N+  H +IH  +          +     +L++  ++ H  E   +  
Sbjct: 235 KCNECGKVFSQPSNLAGHQRIHTGEKPYKCNECGKAFRAHSKLTT-HQVIHTGEKPYKCK 293

Query: 186 APAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCV 242
              K   ++       +    ++ + C  C K F  +  L TH   H+ + P +C+ C  
Sbjct: 294 ECGKCFTQNSHLASHRRIHTGEKPYKCNECGKAFSVRSSLTTHQTIHTGEKPYKCNECGK 353

Query: 243 TFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA 300
            FR +  L +H  +   + P   +  G+ F  ++          G   F C +  ++   
Sbjct: 354 VFRHNSYLAKHRRIHTGEKPYKCNECGKAFSMHSNLTKHQIIHTGEKPFKCNECVKVFTQ 413

Query: 301 WCE-TNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALD 359
           +    N RR  + +  + CD C KAF +  SL  H+  H       EKP      G    
Sbjct: 414 YSHLANHRRIHTGEKPYRCDECGKAFSVRSSLTTHQAIHTG-----EKPYKCNDCGKVFT 468

Query: 360 QKGFLA 365
           Q   LA
Sbjct: 469 QNSHLA 474



 Score =  101 bits (252), Expect = 6e-21
 Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 15/313 (4%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K  T    L  H R H   TG   + C+ CGK+ S  SSL  H  +H+GE+PY
Sbjct: 290 YKCKECGKCFTQNSHLASHRRIH---TGEKPYKCNECGKAFSVRSSLTTHQTIHTGEKPY 346

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC  CG+ F  N  + +H +IH  +          +      L +K ++ H  E   +  
Sbjct: 347 KCNECGKVFRHNSYLAKHRRIHTGEKPYKCNECGKAFSMHSNL-TKHQIIHTGEKPFKCN 405

Query: 186 APAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCV 242
              K   +     +  +    ++ + C  C K F  +  L TH   H+ + P +C+ C  
Sbjct: 406 ECVKVFTQYSHLANHRRIHTGEKPYRCDECGKAFSVRSSLTTHQAIHTGEKPYKCNDCGK 465

Query: 243 TFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQA 300
            F  +  L  H  +   + P   D  G+ F Q +          G   + C +  +    
Sbjct: 466 VFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCNECGKAFSV 525

Query: 301 WCETNLRRCI-SEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALD 359
                + + I + Q  + C+ C K F     LA+H++ H       EKP      G A  
Sbjct: 526 HSSLTIHQTIHTGQKPYKCNDCGKVFRHNSYLAIHQRIHTG-----EKPYKCNECGKAFS 580

Query: 360 QKGFLALLGLQHT 372
               LA   + HT
Sbjct: 581 VHSNLATHQVIHT 593



 Score = 88.6 bits (218), Expect = 5e-17
 Identities = 73/287 (25%), Positives = 110/287 (38%), Gaps = 26/287 (9%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           + C  C K+ T    L  H R H   TG   + C  CGK+ S  SSL  H  +H+GE+PY
Sbjct: 402 FKCNECVKVFTQYSHLANHRRIH---TGEKPYRCDECGKAFSVRSSLTTHQAIHTGEKPY 458

Query: 126 KCTVCGQSFTTNGNMHRHMKIHE-----KDPNSATATAPPSPLKRR-RLSSKRKLSHDAE 179
           KC  CG+ FT N ++  H  IH      K      A +  S L R  R+ +  K     E
Sbjct: 459 KCNDCGKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCNE 518

Query: 180 SER----EDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNP 234
             +           + +  GQ         + + C  C K F     L  H   H+ + P
Sbjct: 519 CGKAFSVHSSLTIHQTIHTGQ---------KPYKCNDCGKVFRHNSYLAIHQRIHTGEKP 569

Query: 235 LRCDICCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            +C+ C   F  H  L  H  +   + P   +  G+ F QN+          G   + C 
Sbjct: 570 YKCNECGKAFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKPYRCN 629

Query: 293 KFPRISQAWCETNLRRCISEQHR-FVCDTCDKAFPMLCSLALHKQTH 338
           +  +             +    + + C+ C K F    +LA H++ H
Sbjct: 630 ECGKAFSVRSTLTTHMAVHTGDKPYKCNQCGKVFTQNSNLAKHRRIH 676



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 88/393 (22%), Positives = 137/393 (34%), Gaps = 59/393 (15%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C +VF   S L  H   HTG+KP+ C KC   F+ +SN   HQ+   G         
Sbjct: 180  CDECGKVFSQNSRLTSHKRIHTGEKPYQCNKCGKAFTVRSNLTIHQVIHTGEKPYKCNEC 239

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQV--AGDAP 1365
            G +  S+ S++  H    +          G+     S+             QV   G+ P
Sbjct: 240  GKV-FSQPSNLAGHQRIHTGEKPYKCNECGKAFRAHSK---------LTTHQVIHTGEKP 289

Query: 1366 VEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLM 1425
             +          +         H  E+ +   E  G A       +++Q++         
Sbjct: 290  YKCKECGKCFTQNSHLASHRRIHTGEKPYKCNEC-GKAFSVRSSLTTHQTIH-------- 340

Query: 1426 DFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGA 1483
                             + E+   C+ CGK F+    L++HR+ H  ++P   +E G   
Sbjct: 341  -----------------TGEKPYKCNECGKVFRHNSYLAKHRRIHTGEKPYKCNECGKAF 383

Query: 1484 STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGP---SDGESAAEKRS 1540
            S      +       + P    E V+           +     E P    +   A   RS
Sbjct: 384  SMHSNLTKHQIIHTGEKPFKCNECVKVFTQYSHLANHRRIHTGEKPYRCDECGKAFSVRS 443

Query: 1541 S-------------EKSDDDKKPKTDSPKSVASK---ADKRKKVCSVCNKRFWSLQDLTR 1584
            S              K +D  K  T +    + +   + ++   C  C K F     L R
Sbjct: 444  SLTTHQAIHTGEKPYKCNDCGKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLAR 503

Query: 1585 HMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            H R HTGE+PYKC  C + F++  SL  HQ IH
Sbjct: 504  HWRVHTGEKPYKCNECGKAFSVHSSLTIHQTIH 536



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 54/181 (29%), Positives = 71/181 (39%), Gaps = 18/181 (9%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H   H G  PY+CN C  +    + L  H   HSGE+PY C 
Sbjct: 430 YRCDECGKAFSVRSSLTTHQAIHTGEKPYKCNDCGKVFTQNSHLASHRGIHSGEKPYKCD 489

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   F+  +   RH R    +K  K    +  K     SS               C  C
Sbjct: 490 ECGKAFSQTSQLARHWRVHTGEKPYKC--NECGKAFSVHSSLTIHQTIHTGQKPYKCNDC 547

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPE 818
           G+  +H   L IH R          H G KP++C EC  AF+   N   H   Q +H  E
Sbjct: 548 GKVFRHNSYLAIHQRI---------HTGEKPYKCNECGKAFSVHSNLATH---QVIHTGE 595

Query: 819 Q 819
           +
Sbjct: 596 K 596



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 56/191 (29%), Positives = 79/191 (41%), Gaps = 18/191 (9%)

Query: 633 KKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRT 692
           +K+P  R   Y C  C +VF+ +  L +H R H G  PYQCN C      ++ L  H   
Sbjct: 168 EKSPNNRGKHYKCDECGKVFSQNSRLTSHKRIHTGEKPYQCNKCGKAFTVRSNLTIHQVI 227

Query: 693 HSGERPYICKICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAF 748
           H+GE+PY C  C   F+  +N   H R    +K  K    +  K     S      V   
Sbjct: 228 HTGEKPYKCNECGKVFSQPSNLAGHQRIHTGEKPYKC--NECGKAFRAHSKLTTHQVIHT 285

Query: 749 CAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
                 C+ CG+       L  H R          H G KP++C EC  AF+ + +   H
Sbjct: 286 GEKPYKCKECGKCFTQNSHLASHRRI---------HTGEKPYKCNECGKAFSVRSSLTTH 336

Query: 809 ILKQHLHVPEQ 819
              Q +H  E+
Sbjct: 337 ---QTIHTGEK 344



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 57/217 (26%), Positives = 88/217 (40%), Gaps = 16/217 (7%)

Query: 28  GKV-TENG--GSPQGIKSPSKPPGPNRIGRRNQETKE---------EKSSYNCPLCEKIC 75
           GKV T+N    S +GI S  KP   +  G+   +T +          +  Y C  C K  
Sbjct: 464 GKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCNECGKAF 523

Query: 76  TTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFT 135
           +    LT+H   H   TG   + C+ CGK     S L  H  +H+GE+PYKC  CG++F+
Sbjct: 524 SVHSSLTIHQTIH---TGQKPYKCNDCGKVFRHNSYLAIHQRIHTGEKPYKCNECGKAFS 580

Query: 136 TNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDG 195
            + N+  H  IH  +             +   L++ R++    +  R +       V   
Sbjct: 581 VHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKPYRCNECGKAFSVRST 640

Query: 196 QSGDLE-KKADEVFHCPVCFKEFVCKYGLETHMETHS 231
            +  +     D+ + C  C K F     L  H   HS
Sbjct: 641 LTTHMAVHTGDKPYKCNQCGKVFTQNSNLAKHRRIHS 677



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 18/181 (9%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C + F  +  L +H R H G  PY+CN C    + +++L  H   H+GE+PY C 
Sbjct: 290 YKCKECGKCFTQNSHLASHRRIHTGEKPYKCNECGKAFSVRSSLTTHQTIHTGEKPYKCN 349

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   F   +   +H R    +K  K    +  K     S+     +         C  C
Sbjct: 350 ECGKVFRHNSYLAKHRRIHTGEKPYKC--NECGKAFSMHSNLTKHQIIHTGEKPFKCNEC 407

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPE 818
            +    Y  L  H R          H G KP+ C EC  AF+ + +   H   Q +H  E
Sbjct: 408 VKVFTQYSHLANHRRI---------HTGEKPYRCDECGKAFSVRSSLTTH---QAIHTGE 455

Query: 819 Q 819
           +
Sbjct: 456 K 456



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 51/190 (26%), Positives = 72/190 (37%), Gaps = 25/190 (13%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C +VF  +  L +H   H G  PY+C+ C    +  + L RH R H+GE+PY C 
Sbjct: 458 YKCNDCGKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCN 517

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   F+V ++   H      +K  K    D  K   + S  A             C  C
Sbjct: 518 ECGKAFSVHSSLTIHQTIHTGQKPYKCN--DCGKVFRHNSYLAIHQRIHTGEKPYKCNEC 575

Query: 759 GEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAF 799
           G+    +  L  H   H          CG+              H G KP+ C EC  AF
Sbjct: 576 GKAFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKPYRCNECGKAF 635

Query: 800 AAKRNCIHHI 809
           + +     H+
Sbjct: 636 SVRSTLTTHM 645



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 28/77 (36%), Positives = 40/77 (51%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C +VF  +  L  H R H G  PY+CN C    + ++ L  H+  H+G++PY C 
Sbjct: 598 YKCNECGKVFTQNSHLANHRRIHTGEKPYRCNECGKAFSVRSTLTTHMAVHTGDKPYKCN 657

Query: 703 ICHYPFTVKANCERHLR 719
            C   FT  +N  +H R
Sbjct: 658 QCGKVFTQNSNLAKHRR 674



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 47/173 (27%), Positives = 69/173 (39%), Gaps = 7/173 (4%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C+ CGK+F    +L+ H+  H  Q+P  +  D           A  Q     E P
Sbjct: 511  EKPYKCNECGKAFSVHSSLTIHQTIHTGQKPY-KCNDCGKVFRHNSYLAIHQRIHTGEKP 569

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADK 1564
             +  E   G   +    LA   +    GE   +     K         +  +    +   
Sbjct: 570  YKCNEC--GKAFSVHSNLATH-QVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKPY 626

Query: 1565 RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            R   C+ C K F     LT HM  HTG++PYKC  C + FT   +L +H+RIH
Sbjct: 627  R---CNECGKAFSVRSTLTTHMAVHTGDKPYKCNQCGKVFTQNSNLAKHRRIH 676



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 55/235 (23%), Positives = 92/235 (39%), Gaps = 14/235 (5%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C+ CGK+F+    L+ H+  H  ++P   K  G    +     A  +     E P
Sbjct: 259  EKPYKCNECGKAFRAHSKLTTHQVIHTGEKPYKCKECGKCFTQNS-HLASHRRIHTGEKP 317

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGP-SDGESAAEKRSSEKSDDDKKPKTDSPKSVASKAD 1563
             +  E     G+A + + +  T      GE   +     K     +  +   K       
Sbjct: 318  YKCNE----CGKAFSVRSSLTTHQTIHTGEKPYKCNECGKVF---RHNSYLAKHRRIHTG 370

Query: 1564 KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKAR 1621
            ++   C+ C K F    +LT+H   HTGE+P+KC  C + FT    L  H+RIH  +K  
Sbjct: 371  EKPYKCNECGKAFSMHSNLTKHQIIHTGEKPFKCNECVKVFTQYSHLANHRRIHTGEKPY 430

Query: 1622 HAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEG 1676
                 GK           + +++ H+G      N+       ++H+A  R    G
Sbjct: 431  RCDECGKAFSVR---SSLTTHQAIHTGEKPYKCNDCGKVFTQNSHLASHRGIHSG 482



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 26/62 (41%), Positives = 31/62 (50%), Gaps = 2/62 (3%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C+ C K F    +L  H R HTGE+PYKC  C + F     L  HQ IH  +K    K  
Sbjct: 236  CNECGKVFSQPSNLAGHQRIHTGEKPYKCNECGKAFRAHSKLTTHQVIHTGEKPYKCKEC 295

Query: 1627 GK 1628
            GK
Sbjct: 296  GK 297



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 51/226 (22%), Positives = 79/226 (34%), Gaps = 40/226 (17%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   CD CGK+F    +L+ H+  H  ++P  +  D      +    A  +     E P
Sbjct: 427  EKPYRCDECGKAFSVRSSLTTHQAIHTGEKPY-KCNDCGKVFTQNSHLASHRGIHSGEKP 485

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADK 1564
             +  E                  G +  +++   R       +K  K             
Sbjct: 486  YKCDEC-----------------GKAFSQTSQLARHWRVHTGEKPYK------------- 515

Query: 1565 RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARH 1622
                C+ C K F     LT H   HTG++PYKC  C + F     L  HQRIH  +K   
Sbjct: 516  ----CNECGKAFSVHSSLTIHQTIHTGQKPYKCNDCGKVFRHNSYLAIHQRIHTGEKPYK 571

Query: 1623 AKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMA 1668
                GK           + ++  H+G      NE       ++H+A
Sbjct: 572  CNECGKAFSVH---SNLATHQVIHTGEKPYKCNECGKVFTQNSHLA 614



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 19/53 (35%), Positives = 26/53 (49%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSG 695
           Y C  C + F+    L  H+  H G  PY+CN C  +    + L +H R HSG
Sbjct: 626 YRCNECGKAFSVRSTLTTHMAVHTGDKPYKCNQCGKVFTQNSNLAKHRRIHSG 678



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 18/46 (39%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S+L  HM  HTG KP+ C +C   F+  SN  +H+
Sbjct: 628  CNECGKAFSVRSTLTTHMAVHTGDKPYKCNQCGKVFTQNSNLAKHR 673



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 20/47 (42%), Positives = 25/47 (53%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQL 1294
            C  C +VF   S L  H   HTG+KP+ C +C   FS  SN   HQ+
Sbjct: 544  CNDCGKVFRHNSYLAIHQRIHTGEKPYKCNECGKAFSVHSNLATHQV 590



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 7/66 (10%)

Query: 1235 KRNSYTNCLQKI-------TCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKS 1287
            + NSY    Q+I        C  C + F   S+L  H + HTG+KP+ C +C   F+  S
Sbjct: 552  RHNSYLAIHQRIHTGEKPYKCNECGKAFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNS 611

Query: 1288 NCERHQ 1293
            +   H+
Sbjct: 612  HLANHR 617



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 18/45 (40%), Positives = 23/45 (51%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            C  C +VF   S L  H   HTG+KP+ C +C   FS +S    H
Sbjct: 600  CNECGKVFTQNSHLANHRRIHTGEKPYRCNECGKAFSVRSTLTTH 644



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 12/101 (11%)

Query: 30  VTENGGSPQGIKSPSKPPGPNRIGR---------RNQETKEEKSSYNCPLCEKICTTQHQ 80
           V  N  + Q I +  KP   N  G+          ++     +  Y C  C K  + +  
Sbjct: 581 VHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKPYRCNECGKAFSVRST 640

Query: 81  LTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSG 121
           LT H+  H   TG   + C+ CGK  +  S+L +H  +HSG
Sbjct: 641 LTTHMAVH---TGDKPYKCNQCGKVFTQNSNLAKHRRIHSG 678



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 19/46 (41%), Positives = 21/46 (45%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   SSL  H   HTGQKP+ C  C   F   S    HQ
Sbjct: 516  CNECGKAFSVHSSLTIHQTIHTGQKPYKCNDCGKVFRHNSYLAIHQ 561


>gi|206725458 zinc finger protein 561 [Homo sapiens]
          Length = 486

 Score =  106 bits (264), Expect = 2e-22
 Identities = 59/182 (32%), Positives = 87/182 (47%), Gaps = 14/182 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C +C + F  S  L  HVR+H GI PY+C  C    A  + L  H+R+HSG++PY CK
Sbjct: 309 HKCTYCGKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIHIRSHSGKKPYQCK 368

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSS--AAELVDAFCAPDTVCRLCGE 760
            C   FT   +  +H R    +   + +E    +++SS  +  L         VC++CG+
Sbjct: 369 ECGKAFTTSTSLIQHTRIHTGEKPYECVECGKTFITSSRRSKHLKTHSGEKPFVCKICGK 428

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD 820
              +   L +H+RT         H G KPF CKEC  AFA       H   + +H  E+ 
Sbjct: 429 AFLYSSRLNVHLRT---------HTGEKPFVCKECGKAFAVSSRLSRH---ERIHTGEKP 476

Query: 821 IE 822
            E
Sbjct: 477 YE 478



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 55/194 (28%), Positives = 84/194 (43%), Gaps = 35/194 (18%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           + C  C K  T   QLT H+R H   TG   + C  CG++ +  S L  H+  HSG++PY
Sbjct: 309 HKCTYCGKAFTRSTQLTEHVRTH---TGIKPYECKECGQAFAQYSGLSIHIRSHSGKKPY 365

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLK--RRRLSSKRKLSHDAESERE 183
           +C  CG++FTT+ ++ +H +IH       T   P   ++  +  ++S R+  H      E
Sbjct: 366 QCKECGKAFTTSTSLIQHTRIH-------TGEKPYECVECGKTFITSSRRSKHLKTHSGE 418

Query: 184 DPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCV 242
            P                      F C +C K F+    L  H+ TH+ + P  C  C  
Sbjct: 419 KP----------------------FVCKICGKAFLYSSRLNVHLRTHTGEKPFVCKECGK 456

Query: 243 TFRTHRGLLRHNAL 256
            F     L RH  +
Sbjct: 457 AFAVSSRLSRHERI 470



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 51/200 (25%), Positives = 78/200 (39%), Gaps = 45/200 (22%)

Query: 623 LKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAAD 682
           LK  +    GKK+   +K       C + F     L A V++H G   ++C  C     +
Sbjct: 240 LKQCVAVHTGKKSKKTKK-------CGKSFTNFSQLYAPVKTHKGEKSFECKECGRSFRN 292

Query: 683 KAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAA 742
            + L  H++ H+G +P+ C  C   FT       H+R      T   I+           
Sbjct: 293 SSCLNDHIQIHTGIKPHKCTYCGKAFTRSTQLTEHVR------THTGIK----------- 335

Query: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802
                       C+ CG+    Y  L IH+R+         H G+KP++CKEC  AF   
Sbjct: 336 ---------PYECKECGQAFAQYSGLSIHIRS---------HSGKKPYQCKECGKAFTTS 377

Query: 803 RNCIHHILKQHLHVPEQDIE 822
            + I H     +H  E+  E
Sbjct: 378 TSLIQH---TRIHTGEKPYE 394



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 65/288 (22%), Positives = 111/288 (38%), Gaps = 44/288 (15%)

Query: 72  EKICTTQHQ-----LTMHIRQH-NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           EK+C  Q        + H++Q     TG        CGKS ++ S L   +  H GE+ +
Sbjct: 222 EKLCEFQEYGRAVTASSHLKQCVAVHTGKKSKKTKKCGKSFTNFSQLYAPVKTHKGEKSF 281

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEK-DPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           +C  CG+SF  +  ++ H++IH    P+  T          +  +   +L+    +    
Sbjct: 282 ECKECGRSFRNSSCLNDHIQIHTGIKPHKCTYCG-------KAFTRSTQLTEHVRTHT-- 332

Query: 185 PAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDN-PLRCDICCVT 243
                                + + C  C + F    GL  H+ +HS   P +C  C   
Sbjct: 333 -------------------GIKPYECKECGQAFAQYSGLSIHIRSHSGKKPYQCKECGKA 373

Query: 244 FRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAW 301
           F T   L++H  +   + P + +  G+ FI ++          G   F C+   +     
Sbjct: 374 FTTSTSLIQHTRIHTGEKPYECVECGKTFITSSRRSKHLKTHSGEKPFVCKICGKAFLYS 433

Query: 302 CETNLR-RCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
              N+  R  + +  FVC  C KAF +   L+ H++ H       EKP
Sbjct: 434 SRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHERIHTG-----EKP 476



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 3/82 (3%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K   T  + + H++ H+   G     C ICGK+   +S L+ H+  H+GE+P+
Sbjct: 393 YECVECGKTFITSSRRSKHLKTHS---GEKPFVCKICGKAFLYSSRLNVHLRTHTGEKPF 449

Query: 126 KCTVCGQSFTTNGNMHRHMKIH 147
            C  CG++F  +  + RH +IH
Sbjct: 450 VCKECGKAFAVSSRLSRHERIH 471



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 7/168 (4%)

Query: 1450 CDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVE 1509
            C  CGK+F     L+ H + H   +P + K  G + A+        +     + P +  E
Sbjct: 311  CTYCGKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIHIRSHSGKK-PYQCKE 369

Query: 1510 SAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVC 1569
               G     +  L + T   + GE   E     K+      ++   K + + + ++  VC
Sbjct: 370  C--GKAFTTSTSLIQHTRIHT-GEKPYECVECGKTFITSSRRS---KHLKTHSGEKPFVC 423

Query: 1570 SVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
             +C K F     L  H+R+HTGE+P+ C+ C + F +   L RH+RIH
Sbjct: 424  KICGKAFLYSSRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHERIH 471



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 24/60 (40%), Positives = 34/60 (56%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C+ C + F +S  L  H+R+H G  P+ C  C    A  + L RH R H+GE+PY CK
Sbjct: 421 FVCKICGKAFLYSSRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHERIHTGEKPYECK 480



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 52/226 (23%), Positives = 85/226 (37%), Gaps = 26/226 (11%)

Query: 1446 QKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD--EKGDGASTAEEGPQPAPEQEEKPPET 1503
            Q   C  CGK FK+  +L  H   H  ++  +  E G   + +    Q       K  + 
Sbjct: 195  QPYKCKECGKGFKYFASLDNHMGIHTDEKLCEFQEYGRAVTASSHLKQCVAVHTGKKSKK 254

Query: 1504 PAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDK-------KP------ 1550
              +  +S     +  A     + E   + +       +    +D        KP      
Sbjct: 255  TKKCGKSFTNFSQLYAPVKTHKGEKSFECKECGRSFRNSSCLNDHIQIHTGIKPHKCTYC 314

Query: 1551 ------KTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTF 1604
                   T   + V +    +   C  C + F     L+ H+RSH+G++PY+C+ C + F
Sbjct: 315  GKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIHIRSHSGKKPYQCKECGKAF 374

Query: 1605 TLKHSLVRHQRIH--QKARHAKHHGKDSDKEERGEEDSENESTHSG 1648
            T   SL++H RIH  +K       GK      R    S++  THSG
Sbjct: 375  TTSTSLIQHTRIHTGEKPYECVECGKTFITSSR---RSKHLKTHSG 417



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 3/73 (4%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++ +T   +  + C +C K      +L +H+R H   TG     C  CGK+ + +S L R
Sbjct: 410 KHLKTHSGEKPFVCKICGKAFLYSSRLNVHLRTH---TGEKPFVCKECGKAFAVSSRLSR 466

Query: 115 HMLVHSGERPYKC 127
           H  +H+GE+PY+C
Sbjct: 467 HERIHTGEKPYEC 479



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 49/188 (26%), Positives = 73/188 (38%), Gaps = 31/188 (16%)

Query: 648 CNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYP 707
           C +VF  +  L  H+       PY+C  C       A+L  H+  H+ E+  +C+   Y 
Sbjct: 174 CGKVFTLTPGLAVHLEVLNARQPYKCKECGKGFKYFASLDNHMGIHTDEK--LCEFQEYG 231

Query: 708 FTVKANCERHLRK-------KHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
             V A+   HL++       K  K T+K   K+    S   A +          C+ CG 
Sbjct: 232 RAVTAS--SHLKQCVAVHTGKKSKKTKK-CGKSFTNFSQLYAPVKTHKGEKSFECKECGR 288

Query: 761 DLKHYRALRIHMR----------THCGRGLGGG---------HKGRKPFECKECSAAFAA 801
             ++   L  H++          T+CG+              H G KP+ECKEC  AFA 
Sbjct: 289 SFRNSSCLNDHIQIHTGIKPHKCTYCGKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQ 348

Query: 802 KRNCIHHI 809
                 HI
Sbjct: 349 YSGLSIHI 356



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 19/46 (41%), Positives = 28/46 (60%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F ++S L  H+ THTG+KPF C++C   F+  S   RH+
Sbjct: 423  CKICGKAFLYSSRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHE 468



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH 1297
            C  C + F  ++SL +H   HTG+KP+ C +C   F T S   +H L+ H
Sbjct: 367  CKECGKAFTTSTSLIQHTRIHTGEKPYECVECGKTFITSSRRSKH-LKTH 415



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 5/82 (6%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C  C K F +    ++H+++H+GE+P+ C+ C + F     L  H R H  +K    K  
Sbjct: 395  CVECGKTFITSSRRSKHLKTHSGEKPFVCKICGKAFLYSSRLNVHLRTHTGEKPFVCKEC 454

Query: 1627 GKDSDKEERGEEDSENESTHSG 1648
            GK      R    S +E  H+G
Sbjct: 455  GKAFAVSSR---LSRHERIHTG 473



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH 1297
            C +C + F  ++ L  H+ THTG KP+ C++C   F+  S    H +R H
Sbjct: 311  CTYCGKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIH-IRSH 359



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 15/45 (33%), Positives = 27/45 (60%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            C  C + F   S L  H+ +H+G+KP+ C++C   F+T ++  +H
Sbjct: 339  CKECGQAFAQYSGLSIHIRSHSGKKPYQCKECGKAFTTSTSLIQH 383



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 1/50 (2%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH 1297
            C  C + F  +S   +H+ TH+G+KPF C+ C   F   S    H LR H
Sbjct: 395  CVECGKTFITSSRRSKHLKTHSGEKPFVCKICGKAFLYSSRLNVH-LRTH 443



 Score = 39.7 bits (91), Expect = 0.026
 Identities = 16/31 (51%), Positives = 20/31 (64%)

Query: 1568 VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQ 1598
            VC  C K F     L+RH R HTGE+PY+C+
Sbjct: 450  VCKECGKAFAVSSRLSRHERIHTGEKPYECK 480



 Score = 35.8 bits (81), Expect = 0.37
 Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH 1297
            C  C R F  +S L  H+  HTG KP  C  C   F+  +    H +R H
Sbjct: 283  CKECGRSFRNSSCLNDHIQIHTGIKPHKCTYCGKAFTRSTQLTEH-VRTH 331



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 50/236 (21%), Positives = 80/236 (33%), Gaps = 20/236 (8%)

Query: 1251 CPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH-----QLRKHGVTTC--S 1303
            C + F   S L   + TH G+K F C++C   F   S    H      ++ H  T C  +
Sbjct: 258  CGKSFTNFSQLYAPVKTHKGEKSFECKECGRSFRNSSCLNDHIQIHTGIKPHKCTYCGKA 317

Query: 1304 LRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGD 1363
              R+  + +   +  G       +     A  +G  + + S   ++P +      +  G 
Sbjct: 318  FTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIHIRSHSGKKPYQC-----KECGK 372

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
            A     T  T+   H   H  GE      E G    T           S +     F  K
Sbjct: 373  A----FTTSTSLIQHTRIH-TGEKPYECVECGKTFITSSRRSKHLKTHSGEK---PFVCK 424

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEK 1479
            +                  + E+   C  CGK+F     LSRH + H  ++P + K
Sbjct: 425  ICGKAFLYSSRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHERIHTGEKPYECK 480



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 13/30 (43%), Positives = 18/30 (60%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQ 1277
            C  C + F  +S L RH   HTG+KP+ C+
Sbjct: 451  CKECGKAFAVSSRLSRHERIHTGEKPYECK 480



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 16/46 (34%), Positives = 20/46 (43%)

Query: 1572 CNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            C K F     L  H+      +PYKC+ C + F    SL  H  IH
Sbjct: 174  CGKVFTLTPGLAVHLEVLNARQPYKCKECGKGFKYFASLDNHMGIH 219


>gi|37537684 zinc finger protein 92 isoform 1 [Homo sapiens]
          Length = 517

 Score =  106 bits (264), Expect = 2e-22
 Identities = 81/316 (25%), Positives = 132/316 (41%), Gaps = 17/316 (5%)

Query: 65  SYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP 124
           SY C  C K       LT H   H   TG   + C  CGK+ + +S+L +H ++H+GE+P
Sbjct: 131 SYKCEECGKAFNWSSTLTKHKIIH---TGEKPYKCEECGKAFNRSSNLTKHKIIHTGEKP 187

Query: 125 YKCTVCGQSFTTNGNMHRHMKIH-EKDPNSATATAPPSPLKRRRLSSKRKLSH--DAESE 181
           YKC  CG++F  +  + +H +IH E+ P             +  + +K K  H  D   +
Sbjct: 188 YKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECG--KAFNQFSILNKHKRIHMEDKPYK 245

Query: 182 REDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDIC 240
            E+   A ++    +   +    ++ + C  C K F     L  H   H+ + P +CD C
Sbjct: 246 CEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCDEC 305

Query: 241 CVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-I 297
              F     L +H  +   + P   +  G+ F Q++          G   + C K  +  
Sbjct: 306 GKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTGEKPYKCEKCGKAF 365

Query: 298 SQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDA 357
           S +   T  +R   E   + C+ C KAF +  +L  HK  H      +EKP      G A
Sbjct: 366 SWSSAFTKHKRNHMEDKPYKCEECGKAFSVFSTLTKHKIIHT-----REKPYKCEECGKA 420

Query: 358 LDQKGFLALLGLQHTK 373
            +Q        + HT+
Sbjct: 421 FNQSSIFTKHKIIHTE 436



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 71/320 (22%), Positives = 119/320 (37%), Gaps = 10/320 (3%)

Query: 22  SAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQL 81
           S+ ++  K+   G  P   +   K    +    +++    E+  Y C  C K       L
Sbjct: 172 SSNLTKHKIIHTGEKPYKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSIL 231

Query: 82  TMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMH 141
             H R H  D     + C  CGK+    S L +H ++H+GE+PYKC  CG++F    N+ 
Sbjct: 232 NKHKRIHMED---KPYKCEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLT 288

Query: 142 RHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES--EREDPAPAKKMVEDGQSGD 199
           +H  IH  +              +    +K K  H  E   + E+   A K         
Sbjct: 289 KHKIIHTGE-KPYKCDECGKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHK 347

Query: 200 LEKKADEVFHCPVCFKEFVCKYGLETHMETH-SDNPLRCDICCVTFRTHRGLLRHNALVH 258
           +    ++ + C  C K F        H   H  D P +C+ C   F     L +H  +  
Sbjct: 348 IIHTGEKPYKCEKCGKAFSWSSAFTKHKRNHMEDKPYKCEECGKAFSVFSTLTKHKIIHT 407

Query: 259 KQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCI-SEQHR 315
           ++ P   +  G+ F Q++              + C K             R+ I + +  
Sbjct: 408 REKPYKCEECGKAFNQSSIFTKHKIIHTEGKSYKCEKCGNAFNQSSNLTARKIIYTGEKP 467

Query: 316 FVCDTCDKAFPMLCSLALHK 335
           +  + CDKAF    +L  H+
Sbjct: 468 YKYEECDKAFNKFSTLITHQ 487



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 86/387 (22%), Positives = 143/387 (36%), Gaps = 31/387 (8%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F W+S+L +H + HTG+KP+ C++C   F+  SN  +H++   G         
Sbjct: 134  CEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAFNRSSNLTKHKIIHTGEKPYKCEEC 193

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G    ++ S +  H    ++         G+  +       Q S      R    D P +
Sbjct: 194  GK-AFNRSSTLTKHKRIHTEEKPYKCEECGKAFN-------QFSILNKHKRIHMEDKPYK 245

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
                  A  V          H  E+ +  EE      G   +  SN +      T    +
Sbjct: 246  CEECGKAFRVFSILKKHKIIHTGEKPYKCEEC-----GKAFNQFSNLTKHKIIHTGEKPY 300

Query: 1428 KLAEGDGEAGAGGAASQEQKL-------ACDTCGKSFKFLGTLSRHRKAHGRQEP-KDEK 1479
            K  E           ++ +++        C+ CGK+FK   TL+ H+  H  ++P K EK
Sbjct: 301  KCDECGKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTGEKPYKCEK 360

Query: 1480 -GDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEK 1538
             G   S +    +      E  P    E  ++          K+    E P   E     
Sbjct: 361  CGKAFSWSSAFTKHKRNHMEDKPYKCEECGKAFSVFSTLTKHKIIHTREKPYKCEECG-- 418

Query: 1539 RSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQ 1598
            ++  +S    K K    +  + K       C  C   F    +LT     +TGE+PYK +
Sbjct: 419  KAFNQSSIFTKHKIIHTEGKSYK-------CEKCGNAFNQSSNLTARKIIYTGEKPYKYE 471

Query: 1599 TCERTFTLKHSLVRHQRIHQKARHAKH 1625
             C++ F    +L+ HQ I+   +  KH
Sbjct: 472  ECDKAFNKFSTLITHQIIYTGEKPCKH 498



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 76/322 (23%), Positives = 118/322 (36%), Gaps = 21/322 (6%)

Query: 71  CEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVC 130
           C+K     H+     R     TG     C   GKS    S L +H  +H+ E  YKC  C
Sbjct: 78  CDKYVKVFHKFPNVNRNKIRHTGKKPFKCKNRGKSFCMLSQLTQHKKIHTREYSYKCEEC 137

Query: 131 GQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKK 190
           G++F  +  + +H  IH  +          +   R    +K K+ H  E   +     K 
Sbjct: 138 GKAFNWSSTLTKHKIIHTGEKPYKCEECGKA-FNRSSNLTKHKIIHTGEKPYKCEECGKA 196

Query: 191 MVEDGQSGDLEK-----KADEVFHCPVCFKEFVCKYGLETHMETH-SDNPLRCDICCVTF 244
                +S  L K       ++ + C  C K F     L  H   H  D P +C+ C   F
Sbjct: 197 F---NRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHMEDKPYKCEECGKAF 253

Query: 245 RTHRGLLRHNALVH---KQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQA 300
           R    +L+ + ++H   K    +  G+ F Q +          G   + C +  +  +Q+
Sbjct: 254 RVF-SILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCDECGKAFNQS 312

Query: 301 WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ 360
              T  +R  + +  + C+ C KAF    +L  HK  H       EKP      G A   
Sbjct: 313 STLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTG-----EKPYKCEKCGKAFSW 367

Query: 361 KGFLALLGLQHTKDVRPAPAEE 382
                     H +D +P   EE
Sbjct: 368 SSAFTKHKRNHMED-KPYKCEE 388



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 46/172 (26%), Positives = 66/172 (38%), Gaps = 11/172 (6%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           R+  Y C  C + F +S  L  H   H G  PY+C  C       + L +H   H+GE+P
Sbjct: 128 REYSYKCEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAFNRSSNLTKHKIIHTGEKP 187

Query: 699 YICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCR 756
           Y C+ C   F   +   +H R    +   K  E    +   S           D    C 
Sbjct: 188 YKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHMEDKPYKCE 247

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            CG+  + +  L+ H            H G KP++C+EC  AF    N   H
Sbjct: 248 ECGKAFRVFSILKKHKII---------HTGEKPYKCEECGKAFNQFSNLTKH 290



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 43/170 (25%), Positives = 64/170 (37%), Gaps = 15/170 (8%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F    +L+ H   H G  PY+C  C       + L +H   H+GE+PY C 
Sbjct: 244 YKCEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCD 303

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   F   +   +H R    +K  K   ++  K  +  S+     +         C  C
Sbjct: 304 ECGKAFNQSSTLTKHKRIHTGEKPYKC--EECGKAFKQSSTLTEHKIIHTGEKPYKCEKC 361

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           G+      A   H R          H   KP++C+EC  AF+       H
Sbjct: 362 GKAFSWSSAFTKHKR---------NHMEDKPYKCEECGKAFSVFSTLTKH 402



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 48/196 (24%), Positives = 77/196 (39%), Gaps = 21/196 (10%)

Query: 1443 SQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQPAPEQEEKP 1500
            ++E    C+ CGK+F +  TL++H+  H  ++P   +E G   + +    +       + 
Sbjct: 127  TREYSYKCEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAFNRSSNLTKHKIIHTGEK 186

Query: 1501 PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAE-----------KRSSEKSDDDKK 1549
            P    E  ++   +      K     E P   E   +           KR   +    K 
Sbjct: 187  PYKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHMEDKPYKC 246

Query: 1550 PKTDSPKSVASKADKRKKV--------CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCE 1601
             +      V S   K K +        C  C K F    +LT+H   HTGE+PYKC  C 
Sbjct: 247  EECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCDECG 306

Query: 1602 RTFTLKHSLVRHQRIH 1617
            + F    +L +H+RIH
Sbjct: 307  KAFNQSSTLTKHKRIH 322



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 65/297 (21%), Positives = 109/297 (36%), Gaps = 18/297 (6%)

Query: 85  IRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHM 144
           + Q  T T      C    K      +++R+ + H+G++P+KC   G+SF     + +H 
Sbjct: 64  LNQCLTTTDSKIFQCDKYVKVFHKFPNVNRNKIRHTGKKPFKCKNRGKSFCMLSQLTQHK 123

Query: 145 KIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK-- 202
           KIH ++  S                +K K+ H  E   +     K      +S +L K  
Sbjct: 124 KIHTRE-YSYKCEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAF---NRSSNLTKHK 179

Query: 203 ---KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVH 258
                ++ + C  C K F     L  H   H+ + P +C+ C   F     L +H  +  
Sbjct: 180 IIHTGEKPYKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHM 239

Query: 259 KQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCI-SEQHR 315
           +  P   +  G+ F   +          G   + C +  +    +      + I + +  
Sbjct: 240 EDKPYKCEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKP 299

Query: 316 FVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
           + CD C KAF    +L  HK+ H       EKP      G A  Q   L    + HT
Sbjct: 300 YKCDECGKAFNQSSTLTKHKRIHTG-----EKPYKCEECGKAFKQSSTLTEHKIIHT 351



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 40/157 (25%), Positives = 60/157 (38%), Gaps = 35/157 (22%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  L  H R H G  PY+C  C       + L  H   H+GE+PY C+
Sbjct: 300 YKCDECGKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTGEKPYKCE 359

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+  +   +H ++ H++      +K  +                   C  CG+  
Sbjct: 360 KCGKAFSWSSAFTKH-KRNHME------DKPYK-------------------CEECGKAF 393

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAF 799
             +  L  H            H   KP++C+EC  AF
Sbjct: 394 SVFSTLTKHKII---------HTREKPYKCEECGKAF 421



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K        T H   H   T G  + C  CG + + +S+L    ++++GE+PY
Sbjct: 412 YKCEECGKAFNQSSIFTKHKIIH---TEGKSYKCEKCGNAFNQSSNLTARKIIYTGEKPY 468

Query: 126 KCTVCGQSFTTNGNMHRHMKIH 147
           K   C ++F     +  H  I+
Sbjct: 469 KYEECDKAFNKFSTLITHQIIY 490



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 1564 KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKAR 1621
            K+   C    K F  L  LT+H + HT E  YKC+ C + F    +L +H+ IH  +K  
Sbjct: 101  KKPFKCKNRGKSFCMLSQLTQHKKIHTREYSYKCEECGKAFNWSSTLTKHKIIHTGEKPY 160

Query: 1622 HAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASN 1665
              +  GK  +   R    ++++  H+G       E   A N S+
Sbjct: 161  KCEECGKAFN---RSSNLTKHKIIHTGEKPYKCEECGKAFNRSS 201



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 1217 GPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPC 1276
            G + ++  +  E K++      Y        C  C + F W+S+  +H   H   KP+ C
Sbjct: 334  GKAFKQSSTLTEHKIIHTGEKPYK-------CEKCGKAFSWSSAFTKHKRNHMEDKPYKC 386

Query: 1277 QKCDAFFSTKSNCERHQL 1294
            ++C   FS  S   +H++
Sbjct: 387  EECGKAFSVFSTLTKHKI 404



 Score = 38.5 bits (88), Expect = 0.058
 Identities = 15/51 (29%), Positives = 29/51 (56%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQK 1619
            C    K F    ++ R+   HTG++P+KC+   ++F +   L +H++IH +
Sbjct: 78   CDKYVKVFHKFPNVNRNKIRHTGKKPFKCKNRGKSFCMLSQLTQHKKIHTR 128



 Score = 37.0 bits (84), Expect = 0.17
 Identities = 26/111 (23%), Positives = 45/111 (40%), Gaps = 4/111 (3%)

Query: 29  KVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQH 88
           K+      P   +   K    + I  +++    E  SY C  C         LT     +
Sbjct: 403 KIIHTREKPYKCEECGKAFNQSSIFTKHKIIHTEGKSYKCEKCGNAFNQSSNLTARKIIY 462

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGN 139
              TG   +    C K+ +  S+L  H ++++GE+P K   CG++F  + N
Sbjct: 463 ---TGEKPYKYEECDKAFNKFSTLITHQIIYTGEKPCK-HECGRAFNKSSN 509



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 2/60 (3%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C   F  S  L A    + G  PY+   CD      + LI H   ++GE+P  CK
Sbjct: 440 YKCEKCGNAFNQSSNLTARKIIYTGEKPYKYEECDKAFNKFSTLITHQIIYTGEKP--CK 497



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 18/70 (25%), Positives = 27/70 (38%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           R+  Y C  C + F  S +   H   H     Y+C  C       + L      ++GE+P
Sbjct: 408 REKPYKCEECGKAFNQSSIFTKHKIIHTEGKSYKCEKCGNAFNQSSNLTARKIIYTGEKP 467

Query: 699 YICKICHYPF 708
           Y  + C   F
Sbjct: 468 YKYEECDKAF 477



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 10/73 (13%)

Query: 1230 KLLRAKRNSYTNCLQK-----ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFS 1284
            K+ +   N    CL         C    +VF    ++ R+ + HTG+KPF C+       
Sbjct: 55   KVYKGGYNGLNQCLTTTDSKIFQCDKYVKVFHKFPNVNRNKIRHTGKKPFKCKN-----R 109

Query: 1285 TKSNCERHQLRKH 1297
             KS C   QL +H
Sbjct: 110  GKSFCMLSQLTQH 122


>gi|55741868 zinc finger protein 319 [Homo sapiens]
          Length = 582

 Score =  106 bits (264), Expect = 2e-22
 Identities = 91/324 (28%), Positives = 127/324 (39%), Gaps = 53/324 (16%)

Query: 37  PQGIKSPSKP--PGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGG 94
           P    +PS P  P P+ +    Q  K     Y+CP+C+K      +L+ H R H   TG 
Sbjct: 175 PATTAAPSLPAAPAPSTVTPAEQADKP----YSCPICQKPFKHLSELSRHERIH---TGE 227

Query: 95  ADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSA 154
             + C++C KS S +S L  H   HS ERPYKC VC ++F    ++ RHM  H  + +  
Sbjct: 228 KPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLF 287

Query: 155 TATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCF 214
                    K     S   L H      E P                      F C  C 
Sbjct: 288 RCNVCELHFK----ESSELLQHPCTPSGERP----------------------FRCGECQ 321

Query: 215 KEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQ-------LPRDAM 266
           K F     L  H  THS + P +CD+C + F+    L+RH    HK        L     
Sbjct: 322 KAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRR-THKTEEPFKCGLCEKGF 380

Query: 267 GRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCI--SEQHRFVCDTCDKA 324
           G+P   ++       H L  T F C    +      E    +C+  + +  F C  C+KA
Sbjct: 381 GQP---SHLLYHQHVHTLE-TLFKCPVCQKGFDQSAELLRHKCLPGAAERPFKCPVCNKA 436

Query: 325 FPMLCSLALHKQTHVAADQGQEKP 348
           +    +L  H+  H AA    EKP
Sbjct: 437 YKRASALQKHQLAHCAA---AEKP 457



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 37/204 (18%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R H G  PY+C +CD   +  + L+ H RTHS ERPY C 
Sbjct: 202 YSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCA 261

Query: 703 ICHYPFTVKANCERHL----RKKHLKATRKDIEKNI-EYVSSSAAELVDAFCAPDTV--- 754
           +C   F  +++  RH+     + HL         N+ E     ++EL+   C P      
Sbjct: 262 VCEKTFKHRSHLVRHMYAHSGEHHL------FRCNVCELHFKESSELLQHPCTPSGERPF 315

Query: 755 -CRLCGEDLKHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKE 794
            C  C +  K    LR H RTH          C  G             HK  +PF+C  
Sbjct: 316 RCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCGL 375

Query: 795 CSAAFAAKRNCIHHILKQHLHVPE 818
           C   F    + ++H   QH+H  E
Sbjct: 376 CEKGFGQPSHLLYH---QHVHTLE 396



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 109/487 (22%), Positives = 172/487 (35%), Gaps = 81/487 (16%)

Query: 1207 EVAGAPADHHGPSDEEQG---SPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQR 1263
            + AG P    G    +     SP E + L     S+        C  C ++F  A+ L  
Sbjct: 69   QAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQ-------CTQCLKIFHQATDLLE 121

Query: 1264 HMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPQSKESDVGSHDS 1323
            H      QKPF C  C   FS  ++     L +H  +   L +  +  ++ +    +  +
Sbjct: 122  HQCVQAEQKPFVCGVCKMGFSLLTS-----LAQHHSSHSGLVKCSICEKTYKPAEAAEPA 176

Query: 1324 TDSQSDAETAAAAGEVLDLTSRDR-------EQPSEGATEL----RQVAGDAPVEQATAE 1372
            T +      A A   V      D+       ++P +  +EL    R   G+ P +    +
Sbjct: 177  TTAAPSLPAAPAPSTVTPAEQADKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCD 236

Query: 1373 TA--SPVHREEHGRGESHEPEEEHGTEESTGD----------ADGAEEDASSNQSLDLDF 1420
             +     H   H R  S E   +    E T            A   E         +L F
Sbjct: 237  KSFSQSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHF 296

Query: 1421 --ATKLMDFKLAEGDGEAGAGGAA-----------------SQEQKLACDTCGKSFKFLG 1461
              +++L+              G                   S E+   CD C   FK   
Sbjct: 297  KESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQY 356

Query: 1462 TLSRHRKAHGRQEPKD----EKGDGASTAEEGPQPAPEQE--------EKPPETPAEVV- 1508
             L RHR+ H  +EP      EKG G  +     Q     E        +K  +  AE++ 
Sbjct: 357  ALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLR 416

Query: 1509 -ESAPGAGEAP--------AEKLAEETEGPSDGESAAEKRSSEKSDDDKK--PKTDSPKS 1557
             +  PGA E P        A K A   +       AA ++    +  +++    ++  + 
Sbjct: 417  HKCLPGAAERPFKCPVCNKAYKRASALQKHQLAHCAAAEKPLRCTLCERRFFSSSEFVQH 476

Query: 1558 VASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                A ++   C  C KRF    DL RH R HTGE+PYKC  C++ F  +  L +HQ +H
Sbjct: 477  RCDPAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVH 536

Query: 1618 QKARHAK 1624
             + +  K
Sbjct: 537  AREQQFK 543



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 60/258 (23%), Positives = 95/258 (36%), Gaps = 28/258 (10%)

Query: 94  GADHS--CSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDP 151
           G D S  C+ C K    A+ L  H  V + ++P+ C VC   F+   ++ +H   H    
Sbjct: 99  GHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSH---- 154

Query: 152 NSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCP 211
                    S L +  +  K     +A       AP+        +    ++AD+ + CP
Sbjct: 155 ---------SGLVKCSICEKTYKPAEAAEPATTAAPSLPAAPAPSTVTPAEQADKPYSCP 205

Query: 212 VCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLP-------R 263
           +C K F     L  H   H+ + P +C +C  +F     L+ H      + P       +
Sbjct: 206 ICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFSQSSHLVHHKRTHSSERPYKCAVCEK 265

Query: 264 DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCI-SEQHRFVCDTCD 322
               R  +  +    +G H L    F C       +   E     C  S +  F C  C 
Sbjct: 266 TFKHRSHLVRHMYAHSGEHHL----FRCNVCELHFKESSELLQHPCTPSGERPFRCGECQ 321

Query: 323 KAFPMLCSLALHKQTHVA 340
           KAF     L  H++TH A
Sbjct: 322 KAFKRPSDLRQHERTHSA 339



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 61/273 (22%), Positives = 91/273 (33%), Gaps = 72/273 (26%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F     LR H R+H    P++C++C      + AL+RH RTH  E P+ C 
Sbjct: 315 FRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMRHRRTHKTEEPFKCG 374

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKD--IEKNIEYVSSSAAELVDAFCAPDTV-----C 755
           +C   F   ++   H     L+   K    +K  +     +AEL+   C P        C
Sbjct: 375 LCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFD----QSAELLRHKCLPGAAERPFKC 430

Query: 756 RLCGEDLKHYRALRIHMRTH------------CGRGLGGG-------------------- 783
            +C +  K   AL+ H   H            C R                         
Sbjct: 431 PVCNKAYKRASALQKHQLAHCAAAEKPLRCTLCERRFFSSSEFVQHRCDPAREKPLKCPD 490

Query: 784 -----------------HKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE---- 822
                            H G KP++C  C  AF  + +   H   Q +H  EQ  +    
Sbjct: 491 CEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKH---QGVHAREQQFKCVWC 547

Query: 823 -----SYVLAADGLGPAEAPAAEASGRGEDSGC 850
                   L  +      A AA A G  + + C
Sbjct: 548 GERFLDVALLQEHSAQHSAAAAAAEGAYQVAAC 580



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 49/198 (24%), Positives = 66/198 (33%), Gaps = 38/198 (19%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           L+ C  C   F  S  L  H  +  G  P++C  C       + L +H RTHS ERP+ C
Sbjct: 286 LFRCNVCELHFKESSELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKC 345

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKD--IEKNIEYVS--------------------- 738
            +C   F  +    RH R    +   K    EK     S                     
Sbjct: 346 DLCPMGFKQQYALMRHRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQ 405

Query: 739 ---SSAAELVDAFCAPDTV-----CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPF 790
                +AEL+   C P        C +C +  K   AL+ H   HC           KP 
Sbjct: 406 KGFDQSAELLRHKCLPGAAERPFKCPVCNKAYKRASALQKHQLAHCA-------AAEKPL 458

Query: 791 ECKECSAAFAAKRNCIHH 808
            C  C   F +    + H
Sbjct: 459 RCTLCERRFFSSSEFVQH 476



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 7/120 (5%)

Query: 37  PQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEK-----ICTTQHQLTMHIRQHNTD 91
           P   + P K P  N+  +R    ++ + ++ C   EK     +C  +   +    QH  D
Sbjct: 421 PGAAERPFKCPVCNKAYKRASALQKHQLAH-CAAAEKPLRCTLCERRFFSSSEFVQHRCD 479

Query: 92  TGGADH-SCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
                   C  C K    AS L RH  VH+GE+PYKC  C ++F    ++++H  +H ++
Sbjct: 480 PAREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHARE 539



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)

Query: 1246 ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLR 1305
            + CP C + F +AS LQRH   HTG+KP+ C  CD  F  + +  +HQ    GV     +
Sbjct: 486  LKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQ----GVHAREQQ 541

Query: 1306 RNGLIPQSKESDVGSHDSTDSQSDAETAAAAG 1337
               +    +  DV       +Q  A  AAA G
Sbjct: 542  FKCVWCGERFLDVALLQEHSAQHSAAAAAAEG 573



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 27/155 (17%)

Query: 671 YQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDI 730
           +QC  C  I      L+ H    + ++P++C +C   F++  +  +H    H    +  I
Sbjct: 104 FQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKMGFSLLTSLAQH-HSSHSGLVKCSI 162

Query: 731 -EKNIEYV-----SSSAAELVDAFCAPDTV-----------CRLCGEDLKHYRALRIHMR 773
            EK  +       +++AA  + A  AP TV           C +C +  KH   L  H R
Sbjct: 163 CEKTYKPAEAAEPATTAAPSLPAAPAPSTVTPAEQADKPYSCPICQKPFKHLSELSRHER 222

Query: 774 THCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
                     H G KP++C  C  +F+   + +HH
Sbjct: 223 I---------HTGEKPYKCTLCDKSFSQSSHLVHH 248



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 68  CPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKC 127
           CP CEK       L  H R H   TG   + C  C K+      L++H  VH+ E+ +KC
Sbjct: 488 CPDCEKRFKYASDLQRHRRVH---TGEKPYKCPNCDKAFKQREHLNKHQGVHAREQQFKC 544

Query: 128 TVCGQSFTTNGNMHRHMKIH 147
             CG+ F     +  H   H
Sbjct: 545 VWCGERFLDVALLQEHSAQH 564



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 636 PAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSG 695
           PA  K L  C  C + F ++  L+ H R H G  PY+C  CD     +  L +H   H+ 
Sbjct: 480 PAREKPL-KCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAR 538

Query: 696 ERPYICKICHYPFTVKANCERH 717
           E+ + C  C   F   A  + H
Sbjct: 539 EQQFKCVWCGERFLDVALLQEH 560



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 8/100 (8%)

Query: 622 ELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGIS--PYQCNICDYI 679
           EL      PG  + P      + C  CN+ +  +  L+ H  +H   +  P +C +C+  
Sbjct: 413 ELLRHKCLPGAAERP------FKCPVCNKAYKRASALQKHQLAHCAAAEKPLRCTLCERR 466

Query: 680 AADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLR 719
               +  ++H    + E+P  C  C   F   ++ +RH R
Sbjct: 467 FFSSSEFVQHRCDPAREKPLKCPDCEKRFKYASDLQRHRR 506



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 30/131 (22%), Positives = 48/131 (36%), Gaps = 7/131 (5%)

Query: 1495 EQEEKPPET-PAEVVESAPGAGEAPAEKLAEETEGPSDGES---AAEKRSSEKSDDDKKP 1550
            E  ++PP+T P +     P     P   LAE T  P   E+    A      + D   +P
Sbjct: 3    ESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQP 62

Query: 1551 KTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSL 1610
               +P   A +   +   C VC      L     H      +R ++C  C + F     L
Sbjct: 63   PQHAPLQAAGEPGPK---CGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDL 119

Query: 1611 VRHQRIHQKAR 1621
            + HQ +  + +
Sbjct: 120  LEHQCVQAEQK 130



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 53/193 (27%), Positives = 73/193 (37%), Gaps = 31/193 (16%)

Query: 968  QPSPCPAPGPSLPVTLGPSGILESPMAPAP---AATPEPPAQPLQ-GPVQLA-------- 1015
            QP     P P+L     P G  E+P+  A       P+P  QP Q  P+Q A        
Sbjct: 20   QPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGLQPPQHAPLQAAGEPGPKCG 79

Query: 1016 VPIYSSALVSSPP----LVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQI 1071
            V  +  A +SSP     L G       T  L+       LL  +    E+ P +  + ++
Sbjct: 80   VCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLLEHQCVQAEQKPFVCGVCKM 139

Query: 1072 ISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPA 1131
              S       L T +A    + +G       S+     K A  A PA T +P   S P A
Sbjct: 140  GFS-------LLTSLAQHHSSHSG---LVKCSICEKTYKPAEAAEPATTAAP---SLPAA 186

Query: 1132 PASSPEAASPTEQ 1144
            PA  P   +P EQ
Sbjct: 187  PA--PSTVTPAEQ 197


>gi|23097323 zinc finger protein 92 isoform 2 [Homo sapiens]
          Length = 586

 Score =  106 bits (264), Expect = 2e-22
 Identities = 81/316 (25%), Positives = 132/316 (41%), Gaps = 17/316 (5%)

Query: 65  SYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP 124
           SY C  C K       LT H   H   TG   + C  CGK+ + +S+L +H ++H+GE+P
Sbjct: 200 SYKCEECGKAFNWSSTLTKHKIIH---TGEKPYKCEECGKAFNRSSNLTKHKIIHTGEKP 256

Query: 125 YKCTVCGQSFTTNGNMHRHMKIH-EKDPNSATATAPPSPLKRRRLSSKRKLSH--DAESE 181
           YKC  CG++F  +  + +H +IH E+ P             +  + +K K  H  D   +
Sbjct: 257 YKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECG--KAFNQFSILNKHKRIHMEDKPYK 314

Query: 182 REDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDIC 240
            E+   A ++    +   +    ++ + C  C K F     L  H   H+ + P +CD C
Sbjct: 315 CEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCDEC 374

Query: 241 CVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-I 297
              F     L +H  +   + P   +  G+ F Q++          G   + C K  +  
Sbjct: 375 GKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTGEKPYKCEKCGKAF 434

Query: 298 SQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDA 357
           S +   T  +R   E   + C+ C KAF +  +L  HK  H      +EKP      G A
Sbjct: 435 SWSSAFTKHKRNHMEDKPYKCEECGKAFSVFSTLTKHKIIHT-----REKPYKCEECGKA 489

Query: 358 LDQKGFLALLGLQHTK 373
            +Q        + HT+
Sbjct: 490 FNQSSIFTKHKIIHTE 505



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 71/320 (22%), Positives = 119/320 (37%), Gaps = 10/320 (3%)

Query: 22  SAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQL 81
           S+ ++  K+   G  P   +   K    +    +++    E+  Y C  C K       L
Sbjct: 241 SSNLTKHKIIHTGEKPYKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSIL 300

Query: 82  TMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMH 141
             H R H  D     + C  CGK+    S L +H ++H+GE+PYKC  CG++F    N+ 
Sbjct: 301 NKHKRIHMED---KPYKCEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLT 357

Query: 142 RHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAES--EREDPAPAKKMVEDGQSGD 199
           +H  IH  +              +    +K K  H  E   + E+   A K         
Sbjct: 358 KHKIIHTGE-KPYKCDECGKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHK 416

Query: 200 LEKKADEVFHCPVCFKEFVCKYGLETHMETH-SDNPLRCDICCVTFRTHRGLLRHNALVH 258
           +    ++ + C  C K F        H   H  D P +C+ C   F     L +H  +  
Sbjct: 417 IIHTGEKPYKCEKCGKAFSWSSAFTKHKRNHMEDKPYKCEECGKAFSVFSTLTKHKIIHT 476

Query: 259 KQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCI-SEQHR 315
           ++ P   +  G+ F Q++              + C K             R+ I + +  
Sbjct: 477 REKPYKCEECGKAFNQSSIFTKHKIIHTEGKSYKCEKCGNAFNQSSNLTARKIIYTGEKP 536

Query: 316 FVCDTCDKAFPMLCSLALHK 335
           +  + CDKAF    +L  H+
Sbjct: 537 YKYEECDKAFNKFSTLITHQ 556



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 86/387 (22%), Positives = 143/387 (36%), Gaps = 31/387 (8%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F W+S+L +H + HTG+KP+ C++C   F+  SN  +H++   G         
Sbjct: 203  CEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAFNRSSNLTKHKIIHTGEKPYKCEEC 262

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G    ++ S +  H    ++         G+  +       Q S      R    D P +
Sbjct: 263  GK-AFNRSSTLTKHKRIHTEEKPYKCEECGKAFN-------QFSILNKHKRIHMEDKPYK 314

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
                  A  V          H  E+ +  EE      G   +  SN +      T    +
Sbjct: 315  CEECGKAFRVFSILKKHKIIHTGEKPYKCEEC-----GKAFNQFSNLTKHKIIHTGEKPY 369

Query: 1428 KLAEGDGEAGAGGAASQEQKL-------ACDTCGKSFKFLGTLSRHRKAHGRQEP-KDEK 1479
            K  E           ++ +++        C+ CGK+FK   TL+ H+  H  ++P K EK
Sbjct: 370  KCDECGKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTGEKPYKCEK 429

Query: 1480 -GDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEK 1538
             G   S +    +      E  P    E  ++          K+    E P   E     
Sbjct: 430  CGKAFSWSSAFTKHKRNHMEDKPYKCEECGKAFSVFSTLTKHKIIHTREKPYKCEECG-- 487

Query: 1539 RSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQ 1598
            ++  +S    K K    +  + K       C  C   F    +LT     +TGE+PYK +
Sbjct: 488  KAFNQSSIFTKHKIIHTEGKSYK-------CEKCGNAFNQSSNLTARKIIYTGEKPYKYE 540

Query: 1599 TCERTFTLKHSLVRHQRIHQKARHAKH 1625
             C++ F    +L+ HQ I+   +  KH
Sbjct: 541  ECDKAFNKFSTLITHQIIYTGEKPCKH 567



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 76/322 (23%), Positives = 118/322 (36%), Gaps = 21/322 (6%)

Query: 71  CEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVC 130
           C+K     H+     R     TG     C   GKS    S L +H  +H+ E  YKC  C
Sbjct: 147 CDKYVKVFHKFPNVNRNKIRHTGKKPFKCKNRGKSFCMLSQLTQHKKIHTREYSYKCEEC 206

Query: 131 GQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKK 190
           G++F  +  + +H  IH  +          +   R    +K K+ H  E   +     K 
Sbjct: 207 GKAFNWSSTLTKHKIIHTGEKPYKCEECGKA-FNRSSNLTKHKIIHTGEKPYKCEECGKA 265

Query: 191 MVEDGQSGDLEK-----KADEVFHCPVCFKEFVCKYGLETHMETH-SDNPLRCDICCVTF 244
                +S  L K       ++ + C  C K F     L  H   H  D P +C+ C   F
Sbjct: 266 F---NRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHMEDKPYKCEECGKAF 322

Query: 245 RTHRGLLRHNALVH---KQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQA 300
           R    +L+ + ++H   K    +  G+ F Q +          G   + C +  +  +Q+
Sbjct: 323 RVF-SILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCDECGKAFNQS 381

Query: 301 WCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQ 360
              T  +R  + +  + C+ C KAF    +L  HK  H       EKP      G A   
Sbjct: 382 STLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTG-----EKPYKCEKCGKAFSW 436

Query: 361 KGFLALLGLQHTKDVRPAPAEE 382
                     H +D +P   EE
Sbjct: 437 SSAFTKHKRNHMED-KPYKCEE 457



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 46/172 (26%), Positives = 66/172 (38%), Gaps = 11/172 (6%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           R+  Y C  C + F +S  L  H   H G  PY+C  C       + L +H   H+GE+P
Sbjct: 197 REYSYKCEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAFNRSSNLTKHKIIHTGEKP 256

Query: 699 YICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCR 756
           Y C+ C   F   +   +H R    +   K  E    +   S           D    C 
Sbjct: 257 YKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHMEDKPYKCE 316

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            CG+  + +  L+ H            H G KP++C+EC  AF    N   H
Sbjct: 317 ECGKAFRVFSILKKHKII---------HTGEKPYKCEECGKAFNQFSNLTKH 359



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 43/170 (25%), Positives = 64/170 (37%), Gaps = 15/170 (8%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F    +L+ H   H G  PY+C  C       + L +H   H+GE+PY C 
Sbjct: 313 YKCEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCD 372

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   F   +   +H R    +K  K   ++  K  +  S+     +         C  C
Sbjct: 373 ECGKAFNQSSTLTKHKRIHTGEKPYKC--EECGKAFKQSSTLTEHKIIHTGEKPYKCEKC 430

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           G+      A   H R          H   KP++C+EC  AF+       H
Sbjct: 431 GKAFSWSSAFTKHKR---------NHMEDKPYKCEECGKAFSVFSTLTKH 471



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 48/196 (24%), Positives = 77/196 (39%), Gaps = 21/196 (10%)

Query: 1443 SQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQPAPEQEEKP 1500
            ++E    C+ CGK+F +  TL++H+  H  ++P   +E G   + +    +       + 
Sbjct: 196  TREYSYKCEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAFNRSSNLTKHKIIHTGEK 255

Query: 1501 PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAE-----------KRSSEKSDDDKK 1549
            P    E  ++   +      K     E P   E   +           KR   +    K 
Sbjct: 256  PYKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHMEDKPYKC 315

Query: 1550 PKTDSPKSVASKADKRKKV--------CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCE 1601
             +      V S   K K +        C  C K F    +LT+H   HTGE+PYKC  C 
Sbjct: 316  EECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCDECG 375

Query: 1602 RTFTLKHSLVRHQRIH 1617
            + F    +L +H+RIH
Sbjct: 376  KAFNQSSTLTKHKRIH 391



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 65/297 (21%), Positives = 109/297 (36%), Gaps = 18/297 (6%)

Query: 85  IRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHM 144
           + Q  T T      C    K      +++R+ + H+G++P+KC   G+SF     + +H 
Sbjct: 133 LNQCLTTTDSKIFQCDKYVKVFHKFPNVNRNKIRHTGKKPFKCKNRGKSFCMLSQLTQHK 192

Query: 145 KIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK-- 202
           KIH ++  S                +K K+ H  E   +     K      +S +L K  
Sbjct: 193 KIHTRE-YSYKCEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAF---NRSSNLTKHK 248

Query: 203 ---KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVH 258
                ++ + C  C K F     L  H   H+ + P +C+ C   F     L +H  +  
Sbjct: 249 IIHTGEKPYKCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHM 308

Query: 259 KQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCI-SEQHR 315
           +  P   +  G+ F   +          G   + C +  +    +      + I + +  
Sbjct: 309 EDKPYKCEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKP 368

Query: 316 FVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
           + CD C KAF    +L  HK+ H       EKP      G A  Q   L    + HT
Sbjct: 369 YKCDECGKAFNQSSTLTKHKRIHTG-----EKPYKCEECGKAFKQSSTLTEHKIIHT 420



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 40/157 (25%), Positives = 60/157 (38%), Gaps = 35/157 (22%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  L  H R H G  PY+C  C       + L  H   H+GE+PY C+
Sbjct: 369 YKCDECGKAFNQSSTLTKHKRIHTGEKPYKCEECGKAFKQSSTLTEHKIIHTGEKPYKCE 428

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+  +   +H ++ H++      +K  +                   C  CG+  
Sbjct: 429 KCGKAFSWSSAFTKH-KRNHME------DKPYK-------------------CEECGKAF 462

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAF 799
             +  L  H            H   KP++C+EC  AF
Sbjct: 463 SVFSTLTKHKII---------HTREKPYKCEECGKAF 490



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K        T H   H   T G  + C  CG + + +S+L    ++++GE+PY
Sbjct: 481 YKCEECGKAFNQSSIFTKHKIIH---TEGKSYKCEKCGNAFNQSSNLTARKIIYTGEKPY 537

Query: 126 KCTVCGQSFTTNGNMHRHMKIH 147
           K   C ++F     +  H  I+
Sbjct: 538 KYEECDKAFNKFSTLITHQIIY 559



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 1564 KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKAR 1621
            K+   C    K F  L  LT+H + HT E  YKC+ C + F    +L +H+ IH  +K  
Sbjct: 170  KKPFKCKNRGKSFCMLSQLTQHKKIHTREYSYKCEECGKAFNWSSTLTKHKIIHTGEKPY 229

Query: 1622 HAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASN 1665
              +  GK  +   R    ++++  H+G       E   A N S+
Sbjct: 230  KCEECGKAFN---RSSNLTKHKIIHTGEKPYKCEECGKAFNRSS 270



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 7/78 (8%)

Query: 1217 GPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPC 1276
            G + ++  +  E K++      Y        C  C + F W+S+  +H   H   KP+ C
Sbjct: 403  GKAFKQSSTLTEHKIIHTGEKPYK-------CEKCGKAFSWSSAFTKHKRNHMEDKPYKC 455

Query: 1277 QKCDAFFSTKSNCERHQL 1294
            ++C   FS  S   +H++
Sbjct: 456  EECGKAFSVFSTLTKHKI 473



 Score = 38.5 bits (88), Expect = 0.058
 Identities = 15/51 (29%), Positives = 29/51 (56%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQK 1619
            C    K F    ++ R+   HTG++P+KC+   ++F +   L +H++IH +
Sbjct: 147  CDKYVKVFHKFPNVNRNKIRHTGKKPFKCKNRGKSFCMLSQLTQHKKIHTR 197



 Score = 37.0 bits (84), Expect = 0.17
 Identities = 26/111 (23%), Positives = 45/111 (40%), Gaps = 4/111 (3%)

Query: 29  KVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQH 88
           K+      P   +   K    + I  +++    E  SY C  C         LT     +
Sbjct: 472 KIIHTREKPYKCEECGKAFNQSSIFTKHKIIHTEGKSYKCEKCGNAFNQSSNLTARKIIY 531

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGN 139
              TG   +    C K+ +  S+L  H ++++GE+P K   CG++F  + N
Sbjct: 532 ---TGEKPYKYEECDKAFNKFSTLITHQIIYTGEKPCK-HECGRAFNKSSN 578



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 2/60 (3%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C   F  S  L A    + G  PY+   CD      + LI H   ++GE+P  CK
Sbjct: 509 YKCEKCGNAFNQSSNLTARKIIYTGEKPYKYEECDKAFNKFSTLITHQIIYTGEKP--CK 566



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 18/70 (25%), Positives = 27/70 (38%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           R+  Y C  C + F  S +   H   H     Y+C  C       + L      ++GE+P
Sbjct: 477 REKPYKCEECGKAFNQSSIFTKHKIIHTEGKSYKCEKCGNAFNQSSNLTARKIIYTGEKP 536

Query: 699 YICKICHYPF 708
           Y  + C   F
Sbjct: 537 YKYEECDKAF 546



 Score = 32.3 bits (72), Expect = 4.1
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 10/73 (13%)

Query: 1230 KLLRAKRNSYTNCLQK-----ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFS 1284
            K+ +   N    CL         C    +VF    ++ R+ + HTG+KPF C+       
Sbjct: 124  KVYKGGYNGLNQCLTTTDSKIFQCDKYVKVFHKFPNVNRNKIRHTGKKPFKCKN-----R 178

Query: 1285 TKSNCERHQLRKH 1297
             KS C   QL +H
Sbjct: 179  GKSFCMLSQLTQH 191


>gi|14211907 zinc finger protein 347 [Homo sapiens]
          Length = 839

 Score =  105 bits (262), Expect = 4e-22
 Identities = 88/351 (25%), Positives = 142/351 (40%), Gaps = 17/351 (4%)

Query: 22  SAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQL 81
           S +++ G+   N GSP            N     +Q +  ++  Y C  C K   T+  L
Sbjct: 245 SLLLTQGQKANNWGSPYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNL 304

Query: 82  TMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMH 141
           T H   H   TG   + C+ CGK  S  S L +H  +H+GE+PYKC  CG+ FT N ++ 
Sbjct: 305 TTHQVIH---TGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLV 361

Query: 142 RHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLE 201
           RH  IH  +             + R   +  + +H  E   +     K   ++    +  
Sbjct: 362 RHRGIHTGE-KPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECGKVFTQNSHLTNHW 420

Query: 202 K--KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVH 258
           +    ++ + C  C K F  +  L  H+  H+ + P +C  C   FR +  L RH  L+H
Sbjct: 421 RIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKPYKCHECGKVFRRNSHLARHQ-LIH 479

Query: 259 ---KQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRI-SQAWCETNLRRCISEQH 314
              K    +  G+ F  ++          G   + C +  ++ +Q     N +R  +   
Sbjct: 480 TGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLANHQRIHTGVK 539

Query: 315 RFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLA 365
            ++C+ C KAF +  SL  H+  H       EKP      G    Q   LA
Sbjct: 540 PYMCNECGKAFSVYSSLTTHQVIHTG-----EKPYKCNECGKVFTQNSHLA 585



 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 75/290 (25%), Positives = 118/290 (40%), Gaps = 17/290 (5%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K+ T    L  H R H   TG   + C+ CGK+ S  SSL  H ++H+GE+PY
Sbjct: 513 YKCNECGKVFTQNSHLANHQRIH---TGVKPYMCNECGKAFSVYSSLTTHQVIHTGEKPY 569

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC  CG+ FT N ++ RH  IH  +             +     S+ +  H  E   +  
Sbjct: 570 KCNECGKVFTQNSHLARHRGIHTGE-KPYKCNECGKVFRHNSYLSRHQRIHTGEKPYKYN 628

Query: 186 APAKKMVEDGQ--SGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCV 242
              K   E     +  +    ++ + C  C K F     L  H   H+   P +C+ C  
Sbjct: 629 EYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQCNECGK 688

Query: 243 TFRTHRGLLRHNALVHKQLPRDA--MGRPF-IQNNPSIPAGFHDLGFTDFSCRKFPRISQ 299
            F     L RH  +   + P +    G+ F ++++ +     H  G   + C +  ++  
Sbjct: 689 AFSQTSKLARHQRVHTGEKPYECNQCGKAFSVRSSLTTHQAIH-TGKKPYKCNECGKVFT 747

Query: 300 AWCETNLRRCI-SEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
                   R I + +  + C+ C KAF     LA H++ H       EKP
Sbjct: 748 QNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARHQRIHTG-----EKP 792



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 57/181 (31%), Positives = 74/181 (40%), Gaps = 18/181 (9%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C +VF  +  L  H   H G  PY+CN C      +++L  H  THSGE+PY C 
Sbjct: 345 YKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCN 404

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   FT  ++   H R    +K  K    +  K     SS A  LV         C  C
Sbjct: 405 ECGKVFTQNSHLTNHWRIHTGEKPYKC--NECGKAFGVRSSLAIHLVIHTGEKPYKCHEC 462

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPE 818
           G+  +    L  H            H G KP++C EC  AF A  N   H   Q +H  E
Sbjct: 463 GKVFRRNSHLARHQLI---------HTGEKPYKCNECGKAFRAHSNLTTH---QVIHTGE 510

Query: 819 Q 819
           +
Sbjct: 511 K 511



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 53/180 (29%), Positives = 70/180 (38%), Gaps = 38/180 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C +VF  +  L  H R H G  PYQCN C    +  + L RH R H+GE+PY C 
Sbjct: 653 YKCNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECN 712

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+V+++   H      K   K                          C  CG+  
Sbjct: 713 QCGKAFSVRSSLTTHQAIHTGKKPYK--------------------------CNECGKVF 746

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
                L  H      RG+   H G KP++C EC  AF+       H   Q +H  E+  E
Sbjct: 747 TQNSHLARH------RGI---HTGEKPYKCNECGKAFSQTSKLARH---QRIHTGEKPYE 794



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 100/458 (21%), Positives = 160/458 (34%), Gaps = 36/458 (7%)

Query: 1244 QKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCS 1303
            ++  C  C +VF   S L +H   HTG+KP+ C +C   F+  S+  RH+    G     
Sbjct: 315  KRYKCNECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYK 374

Query: 1304 LRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLD----LTSRDREQPSEGATELRQ 1359
                G   +++ S +  H +T S          G+V      LT+  R    E   +  +
Sbjct: 375  CNECGKAFRARSS-LAIHQATHSGEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNE 433

Query: 1360 VAGDAPVEQATA------ETASPVHREEHG---RGESHEPEEE---HGTEESTGDADGAE 1407
                  V  + A          P    E G   R  SH    +    G +    +  G  
Sbjct: 434  CGKAFGVRSSLAIHLVIHTGEKPYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKA 493

Query: 1408 EDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKL-------ACDTCGKSFKFL 1460
              A SN +      T    +K  E           +  Q++        C+ CGK+F   
Sbjct: 494  FRAHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLANHQRIHTGVKPYMCNECGKAFSVY 553

Query: 1461 GTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAE 1520
             +L+ H+  H  ++P  +  +      +    A  +     E P +  E           
Sbjct: 554  SSLTTHQVIHTGEKPY-KCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKVFRH---N 609

Query: 1521 KLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQ 1580
                  +    GE   +     K+  +    T     V    +K  K C+ C K F    
Sbjct: 610  SYLSRHQRIHTGEKPYKYNEYGKAFSEHSNLTTH--QVIHTGEKPYK-CNECGKVFTQNS 666

Query: 1581 DLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHHGKDSDKEERGEE 1638
             L RH R HTG +PY+C  C + F+    L RHQR+H  +K       GK          
Sbjct: 667  HLARHRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSVR---SS 723

Query: 1639 DSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEG 1676
             + +++ H+G      NE       ++H+A  R    G
Sbjct: 724  LTTHQAIHTGKKPYKCNECGKVFTQNSHLARHRGIHTG 761



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 40/123 (32%), Positives = 57/123 (46%), Gaps = 3/123 (2%)

Query: 25  MSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMH 84
           ++  +V   G  P       K    N    R++        Y C  C K  +   +L  H
Sbjct: 640 LTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARH 699

Query: 85  IRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHM 144
            R H   TG   + C+ CGK+ S  SSL  H  +H+G++PYKC  CG+ FT N ++ RH 
Sbjct: 700 QRVH---TGEKPYECNQCGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNSHLARHR 756

Query: 145 KIH 147
            IH
Sbjct: 757 GIH 759



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 51/186 (27%), Positives = 73/186 (39%), Gaps = 22/186 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H   H G  PY+CN C  +    + L RH   H+GE+PY C 
Sbjct: 541 YMCNECGKAFSVYSSLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCN 600

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKN------IEYVSSSAAELVDAFCAPDTVCR 756
            C   F   +   RH R   +    K  + N       E+ + +  +++     P   C 
Sbjct: 601 ECGKVFRHNSYLSRHQR---IHTGEKPYKYNEYGKAFSEHSNLTTHQVIHTGEKP-YKCN 656

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L  H R          H G KP++C EC  AF+       H   Q +H 
Sbjct: 657 ECGKVFTQNSHLARHRRV---------HTGGKPYQCNECGKAFSQTSKLARH---QRVHT 704

Query: 817 PEQDIE 822
            E+  E
Sbjct: 705 GEKPYE 710



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 45/170 (26%), Positives = 65/170 (38%), Gaps = 11/170 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H   H G   Y+CN C  + +  + L +H + H+GE+PY C 
Sbjct: 289 YKCYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKPYKCN 348

Query: 703 ICHYPFTVKANCERH--LRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   FT  ++  RH  +          +  K     SS A             C  CG+
Sbjct: 349 ECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECGK 408

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHIL 810
                  L  H R          H G KP++C EC  AF  + +   H++
Sbjct: 409 VFTQNSHLTNHWRI---------HTGEKPYKCNECGKAFGVRSSLAIHLV 449



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 51/182 (28%), Positives = 68/182 (37%), Gaps = 20/182 (10%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C +VF  +  L  H   H G  PY+CN C       + L  H   H+GE+PY C 
Sbjct: 457 YKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCN 516

Query: 703 ICHYPFTVKANCERHLR-----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRL 757
            C   FT  ++   H R     K ++     +  K     SS     V         C  
Sbjct: 517 ECGKVFTQNSHLANHQRIHTGVKPYM---CNECGKAFSVYSSLTTHQVIHTGEKPYKCNE 573

Query: 758 CGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVP 817
           CG+       L  H      RG+   H G KP++C EC   F        H   Q +H  
Sbjct: 574 CGKVFTQNSHLARH------RGI---HTGEKPYKCNECGKVFRHNSYLSRH---QRIHTG 621

Query: 818 EQ 819
           E+
Sbjct: 622 EK 623



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 54/204 (26%), Positives = 74/204 (36%), Gaps = 31/204 (15%)

Query: 1440 GAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEK 1499
            G  + E+   C+ CGK F+    LSRH++ H  ++P      G + +E        Q   
Sbjct: 589  GIHTGEKPYKCNECGKVFRHNSYLSRHQRIHTGEKPYKYNEYGKAFSEHS-NLTTHQVIH 647

Query: 1500 PPETPAEVVESAP--------------------------GAGEAPAEKLAEETEGPSDGE 1533
              E P +  E                             G   +   KLA   +    GE
Sbjct: 648  TGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARH-QRVHTGE 706

Query: 1534 SAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGER 1593
               E     K+   +   T      A    K+   C+ C K F     L RH   HTGE+
Sbjct: 707  KPYECNQCGKAFSVRSSLTTHQ---AIHTGKKPYKCNECGKVFTQNSHLARHRGIHTGEK 763

Query: 1594 PYKCQTCERTFTLKHSLVRHQRIH 1617
            PYKC  C + F+    L RHQRIH
Sbjct: 764  PYKCNECGKAFSQTSKLARHQRIH 787



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 15/119 (12%)

Query: 38  QGIKSPSKPPGPNRIGRR---------NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQH 88
           Q + +  KP   N+ G+          +Q     K  Y C  C K+ T    L  H   H
Sbjct: 700 QRVHTGEKPYECNQCGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNSHLARHRGIH 759

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147
              TG   + C+ CGK+ S  S L RH  +H+GE+PY+   CG+ F+   ++  H  IH
Sbjct: 760 ---TGEKPYKCNECGKAFSQTSKLARHQRIHTGEKPYE---CGKPFSICSSLTTHQTIH 812



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 37/111 (33%), Positives = 55/111 (49%), Gaps = 4/111 (3%)

Query: 1558 VASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            V    +KR K C+ C K F     L++H + HTGE+PYKC  C + FT    LVRH+ IH
Sbjct: 309  VIHTGEKRYK-CNECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIH 367

Query: 1618 QKARHAKHHGKDSDKEERGEED-SENESTHSGNNAVSENEAELAPNASNHM 1667
               +  K +  +  K  R     + +++THSG      NE       ++H+
Sbjct: 368  TGEKPYKCN--ECGKAFRARSSLAIHQATHSGEKPYKCNECGKVFTQNSHL 416



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 54/225 (24%), Positives = 90/225 (40%), Gaps = 8/225 (3%)

Query: 1443 SQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPE 1502
            ++E+   C  CGK+F+    L+ H+  H   E + +  +         Q +  Q+    E
Sbjct: 284  TKEKPYKCYECGKAFRTRSNLTTHQVIH-TGEKRYKCNECGKVFSRNSQLSQHQKIHTGE 342

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKA 1562
             P +  E   G        L     G   GE   +     K+    + ++      A+ +
Sbjct: 343  KPYKCNEC--GKVFTQNSHLVRH-RGIHTGEKPYKCNECGKAF---RARSSLAIHQATHS 396

Query: 1563 DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARH 1622
             ++   C+ C K F     LT H R HTGE+PYKC  C + F ++ SL  H  IH   + 
Sbjct: 397  GEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKP 456

Query: 1623 AKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHM 1667
             K H +      R    + ++  H+G      NE   A  A +++
Sbjct: 457  YKCH-ECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNL 500



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 55/236 (23%), Positives = 89/236 (37%), Gaps = 22/236 (9%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C +VF   S L RH   HTG+KP+ C +C   F   S   RHQ    G         
Sbjct: 571  CNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKVFRHNSYLSRHQRIHTGEKPYKYNEY 630

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G    S+ S++ +H    +          G+V         Q S  A   R   G  P +
Sbjct: 631  GKA-FSEHSNLTTHQVIHTGEKPYKCNECGKVFT-------QNSHLARHRRVHTGGKPYQ 682

Query: 1368 -----QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLD--- 1419
                 +A ++T+     +    GE  +P E +      G A       +++Q++      
Sbjct: 683  CNECGKAFSQTSKLARHQRVHTGE--KPYECN----QCGKAFSVRSSLTTHQAIHTGKKP 736

Query: 1420 FATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEP 1475
            +          +    A   G  + E+   C+ CGK+F     L+RH++ H  ++P
Sbjct: 737  YKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARHQRIHTGEKP 792



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 46/176 (26%), Positives = 75/176 (42%), Gaps = 16/176 (9%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C+ CGK F     L+RHR+ H   +P      G + ++   + A  Q     E P
Sbjct: 650  EKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTS-KLARHQRVHTGEKP 708

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKA-- 1562
             E  +     G+A + + +  T      ++    +   K ++  K  T +      +   
Sbjct: 709  YECNQ----CGKAFSVRSSLTTH-----QAIHTGKKPYKCNECGKVFTQNSHLARHRGIH 759

Query: 1563 -DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
              ++   C+ C K F     L RH R HTGE+PY+   C + F++  SL  HQ IH
Sbjct: 760  TGEKPYKCNECGKAFSQTSKLARHQRIHTGEKPYE---CGKPFSICSSLTTHQTIH 812



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 62/274 (22%), Positives = 96/274 (35%), Gaps = 38/274 (13%)

Query: 104 KSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPL 163
           K   S+  L +    ++   PYK   CG  F  N ++  H + H K+          +  
Sbjct: 240 KDFISSLLLTQGQKANNWGSPYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFR 299

Query: 164 KRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKY 221
            R  L++  ++ H  E   +     K    + Q    +K    ++ + C  C K F    
Sbjct: 300 TRSNLTT-HQVIHTGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNS 358

Query: 222 GLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIP 278
            L  H   H+ + P +C+ C   FR    L  H A    + P   +  G+ F QN+    
Sbjct: 359 HLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECGKVFTQNSHL-- 416

Query: 279 AGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
                                    TN  R  + +  + C+ C KAF +  SLA+H   H
Sbjct: 417 -------------------------TNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIH 451

Query: 339 VAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
                  EKP      G    +   LA   L HT
Sbjct: 452 TG-----EKPYKCHECGKVFRRNSHLARHQLIHT 480



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 13/114 (11%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK 1628
            C  C K F +  +LT H   HTGE+ YKC  C + F+    L +HQ+IH   +  K +  
Sbjct: 291  CYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKPYKCN-- 348

Query: 1629 DSDKEERGEEDSEN------ESTHSGNNAVSENEAELAPNASNHMAVTRSRKEG 1676
                 E G+  ++N         H+G      NE   A  A + +A+ ++   G
Sbjct: 349  -----ECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSG 397



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 1/105 (0%)

Query: 1572 CNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKDSD 1631
            C   F     L  H RSHT E+PYKC  C + F  + +L  HQ IH   +  K + +   
Sbjct: 266  CGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKCN-ECGK 324

Query: 1632 KEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEG 1676
               R  + S+++  H+G      NE       ++H+   R    G
Sbjct: 325  VFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTG 369



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 51/248 (20%), Positives = 85/248 (34%), Gaps = 24/248 (9%)

Query: 1251 CPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLI 1310
            C  VFP  S L  H  +HT +KP+ C +C   F T+SN   HQ+   G         G +
Sbjct: 266  CGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKV 325

Query: 1311 PQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSR----------DREQPSEGATELRQV 1360
              S+ S +  H    +          G+V    S           ++        +  + 
Sbjct: 326  -FSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRA 384

Query: 1361 AGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDAD------GAEEDASSNQ 1414
                 + QAT     P    E G+  +      +     TG+        G      S+ 
Sbjct: 385  RSSLAIHQATHSGEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSL 444

Query: 1415 SLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKL-------ACDTCGKSFKFLGTLSRHR 1467
            ++ L   T    +K  E           ++ Q +        C+ CGK+F+    L+ H+
Sbjct: 445  AIHLVIHTGEKPYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQ 504

Query: 1468 KAHGRQEP 1475
              H  ++P
Sbjct: 505  VIHTGEKP 512



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 32/101 (31%), Positives = 43/101 (42%), Gaps = 15/101 (14%)

Query: 38  QGIKSPSKPPGPNRIGR---------RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQH 88
           Q I +  KP   N  G+         R++     +  Y C  C K  +   +L  H R H
Sbjct: 728 QAIHTGKKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARHQRIH 787

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTV 129
              TG   + C   GK  S  SSL  H  +H+G +PYKC V
Sbjct: 788 ---TGEKPYEC---GKPFSICSSLTTHQTIHTGGKPYKCNV 822



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 1227 PEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTK 1286
            P++  L + + S+T   +   C  C + F   S+L  H + HTG+K + C +C   FS  
Sbjct: 271  PQNSHLASHQRSHTK-EKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKVFSRN 329

Query: 1287 SNCERHQ 1293
            S   +HQ
Sbjct: 330  SQLSQHQ 336



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 11/65 (16%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQC----NICDYIAADKAALIRHLRTHSGERP 698
           Y C  C + F+ +  L  H R H G  PY+C    +IC       ++L  H   H+G +P
Sbjct: 765 YKCNECGKAFSQTSKLARHQRIHTGEKPYECGKPFSIC-------SSLTTHQTIHTGGKP 817

Query: 699 YICKI 703
           Y C +
Sbjct: 818 YKCNV 822



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 7/66 (10%)

Query: 1235 KRNSYTNCLQKITCPHCP-------RVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKS 1287
            + NSY +  Q+I     P       + F   S+L  H + HTG+KP+ C +C   F+  S
Sbjct: 607  RHNSYLSRHQRIHTGEKPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNS 666

Query: 1288 NCERHQ 1293
            +  RH+
Sbjct: 667  HLARHR 672



 Score = 38.1 bits (87), Expect = 0.075
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 3/46 (6%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S L RH   HTG+KP+ C K    FS  S+   HQ
Sbjct: 767  CNECGKAFSQTSKLARHQRIHTGEKPYECGKP---FSICSSLTTHQ 809


>gi|155722996 zinc finger protein 544 [Homo sapiens]
          Length = 715

 Score =  105 bits (262), Expect = 4e-22
 Identities = 86/345 (24%), Positives = 135/345 (39%), Gaps = 48/345 (13%)

Query: 40  IKSPSKPPGPNRIGRR-------NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDT 92
           I++  KP   N+ G+        +Q T   +  + C  C K  +  + L +H R H   T
Sbjct: 347 IQTTEKPSVCNQCGKSFSCCKLIHQRTHTGEKPFECTQCGKSFSQSYDLVIHQRTH---T 403

Query: 93  GGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE-KDP 151
           G   + C +CGKS +  S L  H  +H+GE+PY+C  C +SF  N N+  H +IH  + P
Sbjct: 404 GEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCIECRKSFRWNSNLIVHQRIHTGEKP 463

Query: 152 NSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCP 211
              T            ++ KR  +H  E                          + F C 
Sbjct: 464 YECTHCGKSFSQSYELVTHKR--THTGE--------------------------KPFKCT 495

Query: 212 VCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GR 268
            C K F  KY L  H  TH+ + P  C++C  +F     L+ H  +   + P   +  G+
Sbjct: 496 QCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITHQRIHTGEKPYQCIECGK 555

Query: 269 PFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPM 327
            F  N+  +       G   + C    +  SQ++     +R  + +  + C+ C KAF  
Sbjct: 556 SFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQSYQLVAHKRTHTGEKPYECNECGKAFNR 615

Query: 328 LCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
              L  H Q H       EKP        A  +  +L +    HT
Sbjct: 616 STQLIRHLQIHTG-----EKPYKCNQCNKAFARSSYLVMHQRTHT 655



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 11/225 (4%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           ++ T   +  + C  C K  + ++ L +H R H   TG   + C++CGKS S +S L  H
Sbjct: 482 HKRTHTGEKPFKCTQCGKSFSQKYDLVVHQRTH---TGEKPYECNLCGKSFSQSSKLITH 538

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRKL 174
             +H+GE+PY+C  CG+SF  N N+  H +IH  + P   T          + ++ KR  
Sbjct: 539 QRIHTGEKPYQCIECGKSFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQSYQLVAHKR-- 596

Query: 175 SHDAESEREDPAPAKKMVEDGQ-SGDLE-KKADEVFHCPVCFKEFVCKYGLETHMETHS- 231
           +H  E   E     K      Q    L+    ++ + C  C K F     L  H  TH+ 
Sbjct: 597 THTGEKPYECNECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRTHTG 656

Query: 232 DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNN 274
           + P  C  C   F     LL H+ +   + P +    G+ F Q +
Sbjct: 657 EKPFECSQCGKAFSGSSNLLSHHRIHSGEKPYECSDCGKSFRQQS 701



 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 75/308 (24%), Positives = 123/308 (39%), Gaps = 33/308 (10%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  Y C  C K       L +H R H   TG   + C+ CGKS S +  L  H
Sbjct: 426 HQRIHTGEKPYQCIECRKSFRWNSNLIVHQRIH---TGEKPYECTHCGKSFSQSYELVTH 482

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+P+KCT CG+SF+   ++  H + H  +          S  +  +L + +++ 
Sbjct: 483 KRTHTGEKPFKCTQCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITHQRI- 541

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKK---------ADEVFHCPVCFKEFVCKYGLETH 226
           H  E   +        +E G+S                ++ + C  C K F   Y L  H
Sbjct: 542 HTGEKPYQ-------CIECGKSFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQSYQLVAH 594

Query: 227 METHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHD 283
             TH+ + P  C+ C   F     L+RH  +   + P   +   + F +++  +      
Sbjct: 595 KRTHTGEKPYECNECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRTH 654

Query: 284 LGFTDFSCRKFPRISQAWCETNL---RRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVA 340
            G   F C +  +       +NL    R  S +  + C  C K+F     L +H++TH  
Sbjct: 655 TGEKPFECSQCGKAFSG--SSNLLSHHRIHSGEKPYECSDCGKSFRQQSQLVVHRRTHTG 712

Query: 341 ADQGQEKP 348
                EKP
Sbjct: 713 -----EKP 715



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 56/202 (27%), Positives = 83/202 (41%), Gaps = 32/202 (15%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+ S  L  H R+H G  PY+C++C      ++ LI H R H+GE+PY C 
Sbjct: 380 FECTQCGKSFSQSYDLVIHQRTHTGEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCI 439

Query: 703 ICHYPFTVKANCERHLR----KKHLKATR--KDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F   +N   H R    +K  + T   K   ++ E V+       +        C 
Sbjct: 440 ECRKSFRWNSNLIVHQRIHTGEKPYECTHCGKSFSQSYELVTHKRTHTGE----KPFKCT 495

Query: 757 LCGEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSA 797
            CG+       L +H RTH          CG+              H G KP++C EC  
Sbjct: 496 QCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITHQRIHTGEKPYQCIECGK 555

Query: 798 AFAAKRNCIHHILKQHLHVPEQ 819
           +F    N + H   Q +H  E+
Sbjct: 556 SFRWNSNLVIH---QRIHTGEK 574



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 56/201 (27%), Positives = 81/201 (40%), Gaps = 24/201 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ S  L  H R+H G  P++C  C    + K  L+ H RTH+GE+PY C 
Sbjct: 464 YECTHCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFSQKYDLVVHQRTHTGEKPYECN 523

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIE--KNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
           +C   F+  +    H R    +   + IE  K+  + S+               C  CG+
Sbjct: 524 LCGKSFSQSSKLITHQRIHTGEKPYQCIECGKSFRWNSNLVIHQRIHTGEKPYDCTHCGK 583

Query: 761 DLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFAA 801
                  L  H RTH          CG+              H G KP++C +C+ AFA 
Sbjct: 584 SFSQSYQLVAHKRTHTGEKPYECNECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFAR 643

Query: 802 KRNCIHHILKQHLHVPEQDIE 822
               + H   Q  H  E+  E
Sbjct: 644 SSYLVMH---QRTHTGEKPFE 661



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 54/205 (26%), Positives = 80/205 (39%), Gaps = 32/205 (15%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PY+CN+C    +  + LI H R H+GE+PY C 
Sbjct: 492 FKCTQCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITHQRIHTGEKPYQCI 551

Query: 703 ICHYPFTVKANCERHLR----KKHLKATR--KDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F   +N   H R    +K    T   K   ++ + V+       +        C 
Sbjct: 552 ECGKSFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQSYQLVAHKRTHTGEK----PYECN 607

Query: 757 LCGEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSA 797
            CG+       L  H++ H          C +              H G KPFEC +C  
Sbjct: 608 ECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRTHTGEKPFECSQCGK 667

Query: 798 AFAAKRNCIHHILKQHLHVPEQDIE 822
           AF+   N + H     +H  E+  E
Sbjct: 668 AFSGSSNLLSH---HRIHSGEKPYE 689



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 52/178 (29%), Positives = 76/178 (42%), Gaps = 15/178 (8%)

Query: 648 CNQVF-AFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHY 706
           CNQ   +FS     H R+H G  P++C  C    +    L+ H RTH+GE+PY C +C  
Sbjct: 356 CNQCGKSFSCCKLIHQRTHTGEKPFECTQCGKSFSQSYDLVIHQRTHTGEKPYECDLCGK 415

Query: 707 PFTVKANCERHLRKKHLKATRKDIE--KNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKH 764
            FT ++    H R    +   + IE  K+  + S+               C  CG+    
Sbjct: 416 SFTQRSKLITHQRIHTGEKPYQCIECRKSFRWNSNLIVHQRIHTGEKPYECTHCGKSFSQ 475

Query: 765 YRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
              L  H RT         H G KPF+C +C  +F+ K + + H   Q  H  E+  E
Sbjct: 476 SYELVTHKRT---------HTGEKPFKCTQCGKSFSQKYDLVVH---QRTHTGEKPYE 521



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 47/93 (50%), Gaps = 3/93 (3%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           R+ +    +  Y C  C K       L MH R H   TG     CS CGK+ S +S+L  
Sbjct: 621 RHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRTH---TGEKPFECSQCGKAFSGSSNLLS 677

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147
           H  +HSGE+PY+C+ CG+SF     +  H + H
Sbjct: 678 HHRIHSGEKPYECSDCGKSFRQQSQLVVHRRTH 710



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 63/237 (26%), Positives = 91/237 (38%), Gaps = 36/237 (15%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   CD CGKSF     L  H++ H                 E P    E  +      
Sbjct: 405  EKPYECDLCGKSFTQRSKLITHQRIH---------------TGEKPYQCIECRKSFRWNS 449

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPK--TDSPKSVASKA 1562
              +V      GE P E     T        + E  + +++   +KP   T   KS + K 
Sbjct: 450  NLIVHQRIHTGEKPYEC----THCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFSQKY 505

Query: 1563 D----------KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVR 1612
            D          ++   C++C K F     L  H R HTGE+PY+C  C ++F    +LV 
Sbjct: 506  DLVVHQRTHTGEKPYECNLCGKSFSQSSKLITHQRIHTGEKPYQCIECGKSFRWNSNLVI 565

Query: 1613 HQRIH--QKARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHM 1667
            HQRIH  +K     H GK      +  +   ++ TH+G      NE   A N S  +
Sbjct: 566  HQRIHTGEKPYDCTHCGKSF---SQSYQLVAHKRTHTGEKPYECNECGKAFNRSTQL 619



 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 40/135 (29%), Positives = 57/135 (42%), Gaps = 26/135 (19%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  L  H++ H G  PY+CN C+   A  + L+ H RTH+GE+P+ C 
Sbjct: 604 YECNECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRTHTGEKPFECS 663

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+  +N   H R   + +  K  E                       C  CG+  
Sbjct: 664 QCGKAFSGSSNLLSHHR---IHSGEKPYE-----------------------CSDCGKSF 697

Query: 763 KHYRALRIHMRTHCG 777
           +    L +H RTH G
Sbjct: 698 RQQSQLVVHRRTHTG 712



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 46/171 (26%), Positives = 66/171 (38%), Gaps = 15/171 (8%)

Query: 1450 CDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVE 1509
            C   G  F    +L+  +  H  +  + E  +   T  E       +   P ETP    E
Sbjct: 272  CKDYGNLFSHSVSLNEQKPVHFGKS-QYECDECRETCSESLCLVQTERSGPGETPFRCEE 330

Query: 1510 SA---PGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRK 1566
                 P A       + + TE PS      +  S  K    +    + P           
Sbjct: 331  RCAAFPMASSFSDCNIIQTTEKPSVCNQCGKSFSCCKLIHQRTHTGEKPFE--------- 381

Query: 1567 KVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
              C+ C K F    DL  H R+HTGE+PY+C  C ++FT +  L+ HQRIH
Sbjct: 382  --CTQCGKSFSQSYDLVIHQRTHTGEKPYECDLCGKSFTQRSKLITHQRIH 430



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 60/290 (20%), Positives = 106/290 (36%), Gaps = 41/290 (14%)

Query: 63  KSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGE 122
           KS Y C  C + C+    L   ++   +  G     C     +   ASS     ++ + E
Sbjct: 295 KSQYECDECRETCSESLCL---VQTERSGPGETPFRCEERCAAFPMASSFSDCNIIQTTE 351

Query: 123 RPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESER 182
           +P  C  CG+SF+    +H+     EK            P +  +       S+D    +
Sbjct: 352 KPSVCNQCGKSFSCCKLIHQRTHTGEK------------PFECTQCGKSFSQSYDLVIHQ 399

Query: 183 EDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
                                 ++ + C +C K F  +  L TH   H+ + P +C  C 
Sbjct: 400 R-----------------THTGEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCIECR 442

Query: 242 VTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-IS 298
            +FR +  L+ H  +   + P +    G+ F Q+   +       G   F C +  +  S
Sbjct: 443 KSFRWNSNLIVHQRIHTGEKPYECTHCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFS 502

Query: 299 QAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
           Q +     +R  + +  + C+ C K+F     L  H++ H       EKP
Sbjct: 503 QKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITHQRIHTG-----EKP 547



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 48/179 (26%), Positives = 69/179 (38%), Gaps = 19/179 (10%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C  CGKSF     L  H++ H  ++P +    G S ++   +    Q     E P
Sbjct: 489  EKPFKCTQCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSS-KLITHQRIHTGEKP 547

Query: 1505 AEVVESAPGA---GEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASK 1561
             + +E              +     E P D     +  S             S + VA K
Sbjct: 548  YQCIECGKSFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQ------------SYQLVAHK 595

Query: 1562 ---ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                 ++   C+ C K F     L RH++ HTGE+PYKC  C + F     LV HQR H
Sbjct: 596  RTHTGEKPYECNECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRTH 654



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 35/173 (20%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C  CGKSF++   L  H++ H  ++P D    G S ++     A ++        
Sbjct: 545  EKPYQCIECGKSFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQSYQLVAHKRTH------ 598

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADK 1564
                      GE P E    E  G +   S    R  +    +K  K             
Sbjct: 599  ---------TGEKPYE--CNEC-GKAFNRSTQLIRHLQIHTGEKPYK------------- 633

Query: 1565 RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                C+ CNK F     L  H R+HTGE+P++C  C + F+   +L+ H RIH
Sbjct: 634  ----CNQCNKAFARSSYLVMHQRTHTGEKPFECSQCGKAFSGSSNLLSHHRIH 682



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 67/285 (23%), Positives = 99/285 (34%), Gaps = 40/285 (14%)

Query: 93  GGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPN 152
           G + + C  C ++ S +  L +      GE P++C     +F         M     D N
Sbjct: 294 GKSQYECDECRETCSESLCLVQTERSGPGETPFRCEERCAAFP--------MASSFSDCN 345

Query: 153 SATATAPPSPLKRRRLS-SKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCP 211
               T  PS   +   S S  KL H      E P                      F C 
Sbjct: 346 IIQTTEKPSVCNQCGKSFSCCKLIHQRTHTGEKP----------------------FECT 383

Query: 212 VCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GR 268
            C K F   Y L  H  TH+ + P  CD+C  +F     L+ H  +   + P   +   +
Sbjct: 384 QCGKSFSQSYDLVIHQRTHTGEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCIECRK 443

Query: 269 PFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPM 327
            F  N+  I       G   + C    +  SQ++     +R  + +  F C  C K+F  
Sbjct: 444 SFRWNSNLIVHQRIHTGEKPYECTHCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFSQ 503

Query: 328 LCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
              L +H++TH       EKP    L G +  Q   L      HT
Sbjct: 504 KYDLVVHQRTHTG-----EKPYECNLCGKSFSQSSKLITHQRIHT 543



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 50/203 (24%), Positives = 76/203 (37%), Gaps = 34/203 (16%)

Query: 645 CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC--K 702
           C+    +F+ S  L      H G S Y+C+ C    ++   L++  R+  GE P+ C  +
Sbjct: 272 CKDYGNLFSHSVSLNEQKPVHFGKSQYECDECRETCSESLCLVQTERSGPGETPFRCEER 331

Query: 703 ICHYPFTVK-ANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFC---APDTVCRLC 758
              +P     ++C        ++ T K    N    S S  +L+            C  C
Sbjct: 332 CAAFPMASSFSDC------NIIQTTEKPSVCNQCGKSFSCCKLIHQRTHTGEKPFECTQC 385

Query: 759 GEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAF 799
           G+       L IH RTH          CG+              H G KP++C EC  +F
Sbjct: 386 GKSFSQSYDLVIHQRTHTGEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCIECRKSF 445

Query: 800 AAKRNCIHHILKQHLHVPEQDIE 822
               N I H   Q +H  E+  E
Sbjct: 446 RWNSNLIVH---QRIHTGEKPYE 465



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 21/56 (37%), Positives = 32/56 (57%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           + C  C + F+ S  L +H R H G  PY+C+ C      ++ L+ H RTH+GE+P
Sbjct: 660 FECSQCGKAFSGSSNLLSHHRIHSGEKPYECSDCGKSFRQQSQLVVHRRTHTGEKP 715



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 20/46 (43%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C HC + F  +  L  H  THTG+KPF C +C   FS K +   HQ
Sbjct: 466  CTHCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFSQKYDLVVHQ 511



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 20/45 (44%), Positives = 24/45 (53%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            C  C + F  +S L  H  THTG+KPF C +C   FS  SN   H
Sbjct: 634  CNQCNKAFARSSYLVMHQRTHTGEKPFECSQCGKAFSGSSNLLSH 678



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 74/355 (20%), Positives = 109/355 (30%), Gaps = 85/355 (23%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F W S+L  H   HTG+KP+ C  C   FS       H+    G       + 
Sbjct: 438  CIECRKSFRWNSNLIVHQRIHTGEKPYECTHCGKSFSQSYELVTHKRTHTGEKPFKCTQC 497

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G    S++ D+  H  T +              +L  +   Q S+  T  R   G+ P +
Sbjct: 498  GK-SFSQKYDLVVHQRTHTGEKPYEC-------NLCGKSFSQSSKLITHQRIHTGEKPYQ 549

Query: 1368 QATA------ETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFA 1421
                       +   +H+  H             T E   D     +  S +  L     
Sbjct: 550  CIECGKSFRWNSNLVIHQRIH-------------TGEKPYDCTHCGKSFSQSYQLVAHKR 596

Query: 1422 TKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGD 1481
            T                    + E+   C+ CGK+F     L RH + H           
Sbjct: 597  TH-------------------TGEKPYECNECGKAFNRSTQLIRHLQIH----------- 626

Query: 1482 GASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAE--KLAEETEGPSDGESAAEKR 1539
                  E P    +  +    +   V+      GE P E  +  +   G S+  S     
Sbjct: 627  ----TGEKPYKCNQCNKAFARSSYLVMHQRTHTGEKPFECSQCGKAFSGSSNLLSHHRIH 682

Query: 1540 SSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERP 1594
            S EK  +                      CS C K F     L  H R+HTGE+P
Sbjct: 683  SGEKPYE----------------------CSDCGKSFRQQSQLVVHRRTHTGEKP 715



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 17/46 (36%), Positives = 23/46 (50%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F  +  L  H  THTG+KP+ C  C   F+ +S    HQ
Sbjct: 382  CTQCGKSFSQSYDLVIHQRTHTGEKPYECDLCGKSFTQRSKLITHQ 427



 Score = 38.5 bits (88), Expect = 0.058
 Identities = 18/46 (39%), Positives = 22/46 (47%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S L  H   HTG+KP+ C +C   F   SN   HQ
Sbjct: 410  CDLCGKSFTQRSKLITHQRIHTGEKPYQCIECRKSFRWNSNLIVHQ 455



 Score = 36.2 bits (82), Expect = 0.29
 Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F     +  H  THTG+KPF C +C   FS   +   HQ
Sbjct: 356  CNQCGKSFSCCKLI--HQRTHTGEKPFECTQCGKSFSQSYDLVIHQ 399


>gi|154091003 zinc finger protein 470 [Homo sapiens]
          Length = 717

 Score =  105 bits (261), Expect = 5e-22
 Identities = 86/317 (27%), Positives = 138/317 (43%), Gaps = 40/317 (12%)

Query: 54  RRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLD 113
           +++++ + EK    C  CEKI +    LT+H R H   TG   + C  CGK+ S ++ L 
Sbjct: 216 KKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIH---TGEKPYECIECGKAFSQSAHLA 272

Query: 114 RHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRK 173
           +H  +H+GE+P++CT CG++F+ N ++ +H ++H       T   P    +  +  S  +
Sbjct: 273 QHQRIHTGEKPFECTECGKAFSQNAHLVQHQRVH-------TGEKPYQCKQCNKAFS--Q 323

Query: 174 LSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           L+H A+ +R         V  G         ++ + C  C K F     L  H   H+  
Sbjct: 324 LAHLAQHQR---------VHTG---------EKPYECIECGKAFSDCSSLAHHRRIHTGK 365

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHK-QLPRDAM--GRPFIQNNPSIPAGFHDLGFTDF 289
            P  C  C   FR +  L+RH    H  + P D +  G+ F  +   I       G   +
Sbjct: 366 RPYECIDCGKAFRQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGLIQHKRTHTGERPY 425

Query: 290 SCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C    +  S     T  +R  + +  + C+ C+KAF    SL LH++ H       EKP
Sbjct: 426 KCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTG-----EKP 480

Query: 349 QATPLPGDALDQKGFLA 365
                 G A  Q   LA
Sbjct: 481 YECKECGKAFRQSTHLA 497



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 81/318 (25%), Positives = 131/318 (41%), Gaps = 17/318 (5%)

Query: 54  RRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLD 113
           RR   T E+   ++C  C K  T    L  H R H   TG   + C++CGK+ S  SSL 
Sbjct: 387 RRYYHTGEKP--FDCIDCGKAFTDHIGLIQHKRTH---TGERPYKCNVCGKAFSHGSSLT 441

Query: 114 RHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRK 173
            H  +H+GE+PY+C +C ++F+  G++  H ++H  +          +  +   L+  ++
Sbjct: 442 VHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKPYECKECGKAFRQSTHLAHHQR 501

Query: 174 LSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHS 231
           + H  E   E    +K   ++      +K    ++ + C  C K F     L  H   H+
Sbjct: 502 I-HTGEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHT 560

Query: 232 -DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTD 288
            + P  C  C   F     L++H  L   + P + +  G+ F Q    I       G   
Sbjct: 561 GEKPYECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGKAFRQRASLICHQRCHTGEKP 620

Query: 289 FSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEK 347
           + C    +  S     T  +R  + +  + C  C KAF  +  L LHK+ H       E+
Sbjct: 621 YECNVCGKAFSHRKSLTLHQRIHTGEKPYECKECSKAFSQVAHLTLHKRIHTG-----ER 675

Query: 348 PQATPLPGDALDQKGFLA 365
           P      G A  Q   LA
Sbjct: 676 PYECKECGKAFRQSVHLA 693



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 58/208 (27%), Positives = 79/208 (37%), Gaps = 32/208 (15%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H G  PY+CNIC+   + + +L  H R H+GE+PY CK
Sbjct: 425 YKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKPYECK 484

Query: 703 ICHYPFTVKANCERHLR------KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F    +   H R          K   K   +N            +        C+
Sbjct: 485 ECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIHTGE----KPYECK 540

Query: 757 LCGEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSA 797
            CG+       L  H R H          CG+    G         H G++P+EC EC  
Sbjct: 541 ECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGK 600

Query: 798 AFAAKRNCIHHILKQHLHVPEQDIESYV 825
           AF  + + I H   Q  H  E+  E  V
Sbjct: 601 AFRQRASLICH---QRCHTGEKPYECNV 625



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 54/201 (26%), Positives = 85/201 (42%), Gaps = 26/201 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C++ F+ +  L  H + H G  PY+C  C    +  A L++H R H+GE+PY C 
Sbjct: 509 YECKECSKTFSQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEKPYECI 568

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTV---CRLCG 759
            C   F+  +   +H R    K   + +E    +    A+ +    C        C +CG
Sbjct: 569 ECGKAFSDGSYLVQHQRLHSGKRPYECLECGKAF-RQRASLICHQRCHTGEKPYECNVCG 627

Query: 760 EDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFA 800
           +   H ++L +H R H          C +              H G +P+ECKEC  AF 
Sbjct: 628 KAFSHRKSLTLHQRIHTGEKPYECKECSKAFSQVAHLTLHKRIHTGERPYECKECGKAFR 687

Query: 801 AKRNCIHHILKQHLHVPEQDI 821
              +  HH   Q +H  E  +
Sbjct: 688 QSVHLAHH---QRIHTGESSV 705



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 54/181 (29%), Positives = 72/181 (39%), Gaps = 39/181 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRS-HLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           Y C  C + F  +  L  H R  H G  P+ C  C     D   LI+H RTH+GERPY C
Sbjct: 368 YECIDCGKAFRQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGLIQHKRTHTGERPYKC 427

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGED 761
            +C   F+  ++   H R   +    K  E                       C +C + 
Sbjct: 428 NVCGKAFSHGSSLTVHQR---IHTGEKPYE-----------------------CNICEKA 461

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDI 821
             H  +L +H R          H G KP+ECKEC  AF    +  HH   Q +H  E+  
Sbjct: 462 FSHRGSLTLHQRV---------HTGEKPYECKECGKAFRQSTHLAHH---QRIHTGEKPY 509

Query: 822 E 822
           E
Sbjct: 510 E 510



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 52/168 (30%), Positives = 73/168 (43%), Gaps = 10/168 (5%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ S  L  H R H G  P++C  C    +  A L++H R H+GE+PY CK
Sbjct: 256 YECIECGKAFSQSAHLAQHQRIHTGEKPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCK 315

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIE--KNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C+  F+  A+  +H R    +   + IE  K     SS A             C  CG+
Sbjct: 316 QCNKAFSQLAHLAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRRIHTGKRPYECIDCGK 375

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
             +   +L  H R +        H G KPF+C +C  AF      I H
Sbjct: 376 AFRQNASLIRHRRYY--------HTGEKPFDCIDCGKAFTDHIGLIQH 415



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 97/420 (23%), Positives = 153/420 (36%), Gaps = 52/420 (12%)

Query: 1246 ITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHG-----VT 1300
            + C  C ++F   S+L  H   HTG+KP+ C +C   FS  ++  +HQ    G      T
Sbjct: 228  LKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHTGEKPFECT 287

Query: 1301 TC--SLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQP-------- 1350
             C  +  +N  + Q +    G       Q +   +  A           E+P        
Sbjct: 288  ECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYECIECGK 347

Query: 1351 -----SEGATELRQVAGDAPVE-----QATAETASPV-HREEHGRGESHEPEEEHGTEES 1399
                 S  A   R   G  P E     +A  + AS + HR  +  GE  +P +     ++
Sbjct: 348  AFSDCSSLAHHRRIHTGKRPYECIDCGKAFRQNASLIRHRRYYHTGE--KPFDCIDCGKA 405

Query: 1400 TGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKF 1459
              D  G  +   ++   +  +   +     + G          + E+   C+ C K+F  
Sbjct: 406  FTDHIGLIQHKRTHTG-ERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSH 464

Query: 1460 LGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGE--- 1516
             G+L+ H++ H  ++P + K  G     +    A  Q     E P E  E +    +   
Sbjct: 465  RGSLTLHQRVHTGEKPYECKECG-KAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAH 523

Query: 1517 -------APAEKLAEETEGPSDGESAAEKRSSEKSDDDKKP-------KTDSPKSVASK- 1561
                      EK  E  E        A     ++    +KP       K  S  S   + 
Sbjct: 524  LAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQH 583

Query: 1562 ----ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                + KR   C  C K F     L  H R HTGE+PY+C  C + F+ + SL  HQRIH
Sbjct: 584  QRLHSGKRPYECLECGKAFRQRASLICHQRCHTGEKPYECNVCGKAFSHRKSLTLHQRIH 643



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 17/187 (9%)

Query: 640 KVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPY 699
           K L  C  C ++F+    L  H R H G  PY+C  C    +  A L +H R H+GE+P+
Sbjct: 225 KKLLKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHTGEKPF 284

Query: 700 ICKICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVC 755
            C  C   F+  A+  +H R    +K  +   K   K    ++  A             C
Sbjct: 285 ECTECGKAFSQNAHLVQHQRVHTGEKPYQC--KQCNKAFSQLAHLAQHQRVHTGEKPYEC 342

Query: 756 RLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLH 815
             CG+      +L  H R          H G++P+EC +C  AF    + I H  +++ H
Sbjct: 343 IECGKAFSDCSSLAHHRRI---------HTGKRPYECIDCGKAFRQNASLIRH--RRYYH 391

Query: 816 VPEQDIE 822
             E+  +
Sbjct: 392 TGEKPFD 398



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 55/224 (24%), Positives = 83/224 (37%), Gaps = 31/224 (13%)

Query: 34  GGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTG 93
           G  P   K  SK    N    ++Q+    +  Y C  C K  +    L  H R H   TG
Sbjct: 505 GEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVH---TG 561

Query: 94  GADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNS 153
              + C  CGK+ S  S L +H  +HSG+RPY+C  CG++F    ++  H + H  +   
Sbjct: 562 EKPYECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGKAFRQRASLICHQRCHTGEKPY 621

Query: 154 ATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVC 213
                  +   R+ L+  +++ H  E                          + + C  C
Sbjct: 622 ECNVCGKAFSHRKSLTLHQRI-HTGE--------------------------KPYECKEC 654

Query: 214 FKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNAL 256
            K F     L  H   H+ + P  C  C   FR    L  H  +
Sbjct: 655 SKAFSQVAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQRI 698



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 3/105 (2%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  Y C +C K  + +  LT+H R H   TG   + C  C K+ S  + L  H
Sbjct: 611 HQRCHTGEKPYECNVCGKAFSHRKSLTLHQRIH---TGEKPYECKECSKAFSQVAHLTLH 667

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPP 160
             +H+GERPY+C  CG++F  + ++  H +IH  + +   ++A P
Sbjct: 668 KRIHTGERPYECKECGKAFRQSVHLAHHQRIHTGESSVILSSALP 712



 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 63/251 (25%), Positives = 98/251 (39%), Gaps = 33/251 (13%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C  CGK+F     L +H++ H  ++P   K    + ++     A  Q     E P
Sbjct: 281  EKPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAFSQLA-HLAQHQRVHTGEKP 339

Query: 1505 AEVVESAPGAGEAPAEKLAEETE-------------GPSDGESAAEKRSSEKSDDDKKPK 1551
             E +E   G   +    LA                 G +  ++A+  R        +KP 
Sbjct: 340  YECIEC--GKAFSDCSSLAHHRRIHTGKRPYECIDCGKAFRQNASLIRHRRYYHTGEKPF 397

Query: 1552 ---------TDSPKSVASK---ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQT 1599
                     TD    +  K     +R   C+VC K F     LT H R HTGE+PY+C  
Sbjct: 398  DCIDCGKAFTDHIGLIQHKRTHTGERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNI 457

Query: 1600 CERTFTLKHSLVRHQRIH--QKARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEA 1657
            CE+ F+ + SL  HQR+H  +K    K  GK      +    + ++  H+G       E 
Sbjct: 458  CEKAFSHRGSLTLHQRVHTGEKPYECKECGK---AFRQSTHLAHHQRIHTGEKPYECKEC 514

Query: 1658 ELAPNASNHMA 1668
                + + H+A
Sbjct: 515  SKTFSQNAHLA 525



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 47/177 (26%), Positives = 73/177 (41%), Gaps = 7/177 (3%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C+ CGK+F    +L+ H++ H  ++P +      + +  G      Q     E P
Sbjct: 422  ERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTL-HQRVHTGEKP 480

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADK 1564
             E  E   G     +  LA   +    GE   E +   K+           K       +
Sbjct: 481  YECKEC--GKAFRQSTHLAHH-QRIHTGEKPYECKECSKTFSQNAHLAQHQK---IHTGE 534

Query: 1565 RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKAR 1621
            +   C  C K F  +  L +H R HTGE+PY+C  C + F+    LV+HQR+H   R
Sbjct: 535  KPYECKECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQHQRLHSGKR 591



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 32/83 (38%), Positives = 43/83 (51%), Gaps = 2/83 (2%)

Query: 1537 EKRSSEKSDDDKKPKTDS--PKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERP 1594
            E+R      D K  KT S   K    + +K+   C+ C K F  +  LT H R HTGE+P
Sbjct: 196  EERIFNFHTDKKSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGEKP 255

Query: 1595 YKCQTCERTFTLKHSLVRHQRIH 1617
            Y+C  C + F+    L +HQRIH
Sbjct: 256  YECIECGKAFSQSAHLAQHQRIH 278



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 19/279 (6%)

Query: 104 KSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPL 163
           KSL + S + +H      ++  KC  C + F+    +  H +IH  +          +  
Sbjct: 207 KSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFS 266

Query: 164 KRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKY 221
           +   L+  +++ H  E   E     K   ++      ++    ++ + C  C K F    
Sbjct: 267 QSAHLAQHQRI-HTGEKPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAFSQLA 325

Query: 222 GLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSI- 277
            L  H   H+ + P  C  C   F     L  H  +   + P + +  G+ F QN   I 
Sbjct: 326 HLAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRRIHTGKRPYECIDCGKAFRQNASLIR 385

Query: 278 PAGFHDLGFTDFSCRKFPRISQAWCE----TNLRRCISEQHRFVCDTCDKAFPMLCSLAL 333
              ++  G   F C       +A+ +       +R  + +  + C+ C KAF    SL +
Sbjct: 386 HRRYYHTGEKPFDCID---CGKAFTDHIGLIQHKRTHTGERPYKCNVCGKAFSHGSSLTV 442

Query: 334 HKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
           H++ H       EKP    +   A   +G L L    HT
Sbjct: 443 HQRIHTG-----EKPYECNICEKAFSHRGSLTLHQRVHT 476



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 20/58 (34%), Positives = 26/58 (44%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYI 700
           Y C+ C++ F+    L  H R H G  PY+C  C         L  H R H+GE   I
Sbjct: 649 YECKECSKAFSQVAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQRIHTGESSVI 706



 Score = 39.7 bits (91), Expect = 0.026
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F    SL  H   HTG+KP+ C++C   FS  ++   H+
Sbjct: 623  CNVCGKAFSHRKSLTLHQRIHTGEKPYECKECSKAFSQVAHLTLHK 668



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 1/63 (1%)

Query: 1231 LLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCE 1290
            L+R +R  +T   +   C  C + F     L +H  THTG++P+ C  C   FS  S+  
Sbjct: 383  LIRHRRYYHTG-EKPFDCIDCGKAFTDHIGLIQHKRTHTGERPYKCNVCGKAFSHGSSLT 441

Query: 1291 RHQ 1293
             HQ
Sbjct: 442  VHQ 444



 Score = 38.5 bits (88), Expect = 0.058
 Identities = 14/46 (30%), Positives = 22/46 (47%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   + L  H   HTG++P+ C++C   F    +   HQ
Sbjct: 651  CKECSKAFSQVAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQ 696


>gi|157412267 zinc finger protein 221 [Homo sapiens]
          Length = 617

 Score =  105 bits (261), Expect = 5e-22
 Identities = 75/297 (25%), Positives = 126/297 (42%), Gaps = 12/297 (4%)

Query: 49  PNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSS 108
           P +I  R   +  ++  Y C  C++  +      +H + H+   G   H+C  CGKS   
Sbjct: 153 PCQIEARLSISHVQQKPYRCNECKQSFSDVSVFDLHQQSHS---GEKSHTCGECGKSFCY 209

Query: 109 ASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRL 168
           + +L  H  VH GE+ YKC VCG+ F  + ++  H ++H  +              R  L
Sbjct: 210 SPALHIHQRVHMGEKCYKCDVCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHSRSAL 269

Query: 169 SSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETH 226
           +   KL H  E         K  + D Q  + ++    ++ F C +C K F  +  L  H
Sbjct: 270 NVHCKL-HTGEKPYNCEECGKAFIHDSQLQEHQRIHTGEKPFKCDICGKSFRVRSRLNRH 328

Query: 227 METHS-DNPLRCDICCVTFRTHRGLLRHNALVH---KQLPRDAMGRPFIQNNPSIPAGFH 282
              H+ + P RCD C   FR  R  L  +++VH   K    +  G+ FI           
Sbjct: 329 SMVHTGEKPFRCDTCGKNFR-QRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFCKHQMV 387

Query: 283 DLGFTDFSCRKFPRISQ-AWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
             G   ++C++  +  + + C  N ++  S Q  F C+ C K F      + H+++H
Sbjct: 388 HTGEKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYTNSRRSSHQRSH 444



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 68/288 (23%), Positives = 111/288 (38%), Gaps = 36/288 (12%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  + C  C K   ++  L +H + H   TG   ++C  CGK+    S L  H
Sbjct: 244 HQRVHTGEKPFKCGQCGKGFHSRSALNVHCKLH---TGEKPYNCEECGKAFIHDSQLQEH 300

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
             +H+GE+P+KC +CG+SF     ++RH  +H  +      T   +  +R  L+     S
Sbjct: 301 QRIHTGEKPFKCDICGKSFRVRSRLNRHSMVHTGEKPFRCDTCGKNFRQRSALN-----S 355

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNP 234
           H      E P                      + C  C K F+C+     H   H+ + P
Sbjct: 356 HSMVHIEEKP----------------------YKCEQCGKGFICRRDFCKHQMVHTGEKP 393

Query: 235 LRCDICCVTFRTHRGLLRHNALVH---KQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSC 291
             C  C  TFR    LL H   VH   K    +  G+ F  N+          G   ++C
Sbjct: 394 YNCKECGKTFRWSSCLLNHQQ-VHSGQKSFKCEECGKGFYTNSRRSSHQRSHNGEKPYNC 452

Query: 292 RKFPRISQAWCETNLRRCISEQHR-FVCDTCDKAFPMLCSLALHKQTH 338
            +  +  +   +    + +    R + C  C K+F     L  H++ H
Sbjct: 453 EECGKDYKRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLKHQRLH 500



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 72/298 (24%), Positives = 118/298 (39%), Gaps = 33/298 (11%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           YNC  C K      QL  H R H   TG     C ICGKS    S L+RH +VH+GE+P+
Sbjct: 282 YNCEECGKAFIHDSQLQEHQRIH---TGEKPFKCDICGKSFRVRSRLNRHSMVHTGEKPF 338

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           +C  CG++F     ++ H  +H ++            + RR    K ++ H  E      
Sbjct: 339 RCDTCGKNFRQRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFC-KHQMVHTGEKPYNCK 397

Query: 186 APAK-----------KMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DN 233
              K           + V  GQ           F C  C K F       +H  +H+ + 
Sbjct: 398 ECGKTFRWSSCLLNHQQVHSGQKS---------FKCEECGKGFYTNSRRSSHQRSHNGEK 448

Query: 234 PLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSC 291
           P  C+ C   ++    L  H  +   + P +    G+ F   +  +       G   F C
Sbjct: 449 PYNCEECGKDYKRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLKHQRLHSGEKPFKC 508

Query: 292 RKF-PRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            +   R +Q+    + + C + +  + C+ C+K +    +L +H++ H     G E+P
Sbjct: 509 EECGKRFTQSSQLHSHQTCHTGEKLYKCEQCEKGYNSKFNLDMHQRVH-----GGERP 561



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q +   +  YNC  C K    +  L  H R H   TG   ++C  CGKS   AS L +H
Sbjct: 440 HQRSHNGEKPYNCEECGKDYKRRLDLEFHQRVH---TGERPYNCKECGKSFGWASCLLKH 496

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147
             +HSGE+P+KC  CG+ FT +  +H H   H
Sbjct: 497 QRLHSGEKPFKCEECGKRFTQSSQLHSHQTCH 528



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 51/195 (26%), Positives = 76/195 (38%), Gaps = 27/195 (13%)

Query: 638 MRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGER 697
           M +  Y C  C + F  S  L+ H R H G  P++C  C      ++AL  H + H+GE+
Sbjct: 221 MGEKCYKCDVCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHSRSALNVHCKLHTGEK 280

Query: 698 PYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT---- 753
           PY C+ C   F   +  + H R   +    K  + +I   S      ++      T    
Sbjct: 281 PYNCEECGKAFIHDSQLQEHQR---IHTGEKPFKCDICGKSFRVRSRLNRHSMVHTGEKP 337

Query: 754 -VCRLCGEDLKHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECK 793
             C  CG++ +   AL  H   H          CG+G             H G KP+ CK
Sbjct: 338 FRCDTCGKNFRQRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFCKHQMVHTGEKPYNCK 397

Query: 794 ECSAAFAAKRNCIHH 808
           EC   F      ++H
Sbjct: 398 ECGKTFRWSSCLLNH 412



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 51/185 (27%), Positives = 72/185 (38%), Gaps = 14/185 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F  +    +H RSH G  PY C  C      +  L  H R H+GERPY CK
Sbjct: 422 FKCEECGKGFYTNSRRSSHQRSHNGEKPYNCEECGKDYKRRLDLEFHQRVHTGERPYNCK 481

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTV--CRLCGE 760
            C   F   +   +H R    +   K  E    +  SS           + +  C  C +
Sbjct: 482 ECGKSFGWASCLLKHQRLHSGEKPFKCEECGKRFTQSSQLHSHQTCHTGEKLYKCEQCEK 541

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQD 820
                  L +H R          H G +P+ CKEC  +F      + H   Q LH  E+ 
Sbjct: 542 GYNSKFNLDMHQRV---------HGGERPYNCKECGKSFGWASCLLKH---QRLHSGEKP 589

Query: 821 IESYV 825
           ++S V
Sbjct: 590 LKSGV 594



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 85/402 (21%), Positives = 142/402 (35%), Gaps = 54/402 (13%)

Query: 1263 RHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVT--TCSLRRNGLIPQSKESDVGS 1320
            R  ++H  QKP+ C +C   FS  S  + HQ    G    TC              + G 
Sbjct: 159  RLSISHVQQKPYRCNECKQSFSDVSVFDLHQQSHSGEKSHTCG-------------ECGK 205

Query: 1321 HDSTDSQSDAETAAAAGEVL---DLTSRDREQPSEGATELRQVAGDAPVEQATAETASPV 1377
                            GE     D+  ++  Q S   T  R   G+ P +          
Sbjct: 206  SFCYSPALHIHQRVHMGEKCYKCDVCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHS 265

Query: 1378 HREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---DLDFATKLMDFKLAEGDG 1434
                +   + H  E+ +  EE  G A   +     +Q +   +  F   +          
Sbjct: 266  RSALNVHCKLHTGEKPYNCEEC-GKAFIHDSQLQEHQRIHTGEKPFKCDICGKSFRVRSR 324

Query: 1435 EAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQP 1492
                    + E+   CDTCGK+F+    L+ H   H  ++P   ++ G G     +  + 
Sbjct: 325  LNRHSMVHTGEKPFRCDTCGKNFRQRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFCKH 384

Query: 1493 APEQEEKPPETPAEVVESAPGAG------EAPAEKLAEETEGPSDGESAAEKRSS-EKSD 1545
                  + P    E  ++   +       +  + + + + E    G     +RSS ++S 
Sbjct: 385  QMVHTGEKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYTNSRRSSHQRSH 444

Query: 1546 DDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFT 1605
            + +KP                  C  C K +    DL  H R HTGERPY C+ C ++F 
Sbjct: 445  NGEKPYN----------------CEECGKDYKRRLDLEFHQRVHTGERPYNCKECGKSFG 488

Query: 1606 LKHSLVRHQRIHQKARHAKHHGKDSDKEERGEEDSENESTHS 1647
                L++HQR+H   +  K        EE G+  +++   HS
Sbjct: 489  WASCLLKHQRLHSGEKPFK-------CEECGKRFTQSSQLHS 523



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 47/171 (27%), Positives = 65/171 (38%), Gaps = 17/171 (9%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C Q F+   V   H +SH G   + C  C        AL  H R H GE+ Y C 
Sbjct: 170 YRCNECKQSFSDVSVFDLHQQSHSGEKSHTCGECGKSFCYSPALHIHQRVHMGEKCYKCD 229

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT-----VCRL 757
           +C   F   ++ + H R    +   K  +    + S SA   ++  C   T      C  
Sbjct: 230 VCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHSRSA---LNVHCKLHTGEKPYNCEE 286

Query: 758 CGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           CG+   H   L+ H R          H G KPF+C  C  +F  +     H
Sbjct: 287 CGKAFIHDSQLQEHQRI---------HTGEKPFKCDICGKSFRVRSRLNRH 328



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 37/114 (32%), Positives = 49/114 (42%), Gaps = 3/114 (2%)

Query: 34  GGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTG 93
           G  P   K   K  G      ++Q     +  + C  C K  T   QL  H   H   TG
Sbjct: 474 GERPYNCKECGKSFGWASCLLKHQRLHSGEKPFKCEECGKRFTQSSQLHSHQTCH---TG 530

Query: 94  GADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147
              + C  C K  +S  +LD H  VH GERPY C  CG+SF     + +H ++H
Sbjct: 531 EKLYKCEQCEKGYNSKFNLDMHQRVHGGERPYNCKECGKSFGWASCLLKHQRLH 584



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 44/185 (23%), Positives = 60/185 (32%), Gaps = 45/185 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F        H   H G  PY C  C       + L+ H + HSG++ + C+
Sbjct: 366 YKCEQCGKGFICRRDFCKHQMVHTGEKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCE 425

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F   +      R  H ++   +   N                     C  CG+D 
Sbjct: 426 ECGKGFYTNSR-----RSSHQRSHNGEKPYN---------------------CEECGKDY 459

Query: 763 KHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFAAKR 803
           K    L  H R H          CG+  G           H G KPF+C+EC   F    
Sbjct: 460 KRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLKHQRLHSGEKPFKCEECGKRFTQSS 519

Query: 804 NCIHH 808
               H
Sbjct: 520 QLHSH 524



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 50/194 (25%), Positives = 81/194 (41%), Gaps = 25/194 (12%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQPAPEQEEKPPE 1502
            E+   C  CGK+F++   L  H++ H  Q+    +E G G  T     + +  Q     E
Sbjct: 391  EKPYNCKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYT---NSRRSSHQRSHNGE 447

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKK-PKTDSPKSVASK 1561
             P               E+  ++ +   D E      + E+  + K+  K+    S   K
Sbjct: 448  KPYN------------CEECGKDYKRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLK 495

Query: 1562 -----ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRI 1616
                 + ++   C  C KRF     L  H   HTGE+ YKC+ CE+ +  K +L  HQR+
Sbjct: 496  HQRLHSGEKPFKCEECGKRFTQSSQLHSHQTCHTGEKLYKCEQCEKGYNSKFNLDMHQRV 555

Query: 1617 H--QKARHAKHHGK 1628
            H  ++  + K  GK
Sbjct: 556  HGGERPYNCKECGK 569



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 53/217 (24%), Positives = 88/217 (40%), Gaps = 34/217 (15%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C  CGK F     L+ H K H  ++P + +  G +   +       QE +   T 
Sbjct: 251  EKPFKCGQCGKGFHSRSALNVHCKLHTGEKPYNCEECGKAFIHDSQL----QEHQRIHT- 305

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDS-PKSVASKA- 1562
                      GE P +    +  G S    +   R S     +K  + D+  K+   ++ 
Sbjct: 306  ----------GEKPFKC---DICGKSFRVRSRLNRHSMVHTGEKPFRCDTCGKNFRQRSA 352

Query: 1563 ---------DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRH 1613
                     +++   C  C K F   +D  +H   HTGE+PY C+ C +TF     L+ H
Sbjct: 353  LNSHSMVHIEEKPYKCEQCGKGFICRRDFCKHQMVHTGEKPYNCKECGKTFRWSSCLLNH 412

Query: 1614 QRIH--QKARHAKHHGKDSDKEERGEEDSENESTHSG 1648
            Q++H  QK+   +  GK      R    S ++ +H+G
Sbjct: 413  QQVHSGQKSFKCEECGKGFYTNSR---RSSHQRSHNG 446



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 41/158 (25%), Positives = 60/158 (37%), Gaps = 14/158 (8%)

Query: 664 SHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHL 723
           SH+   PY+CN C    +D +    H ++HSGE+ + C  C   F        H R    
Sbjct: 163 SHVQQKPYRCNECKQSFSDVSVFDLHQQSHSGEKSHTCGECGKSFCYSPALHIHQRVHMG 222

Query: 724 KATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGEDLKHYRALRIHMRTHCGRGLG 781
           +   K      E+  SS  +        +    C  CG+      AL +H +        
Sbjct: 223 EKCYKCDVCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHSRSALNVHCKL------- 275

Query: 782 GGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
             H G KP+ C+EC  AF        H   Q +H  E+
Sbjct: 276 --HTGEKPYNCEECGKAFIHDSQLQEH---QRIHTGEK 308



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 45/185 (24%), Positives = 70/185 (37%), Gaps = 13/185 (7%)

Query: 1443 SQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPE 1502
            S ++   C+ CGK F      S H+++H  ++P + +  G             Q     E
Sbjct: 417  SGQKSFKCEECGKGFYTNSRRSSHQRSHNGEKPYNCEECGKDYKRRLDLEF-HQRVHTGE 475

Query: 1503 TPAEVVESAPGAGEAPA---EKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVA 1559
             P    E     G A      +     E P   E    KR ++ S         + + + 
Sbjct: 476  RPYNCKECGKSFGWASCLLKHQRLHSGEKPFKCEECG-KRFTQSSQLHSHQTCHTGEKLY 534

Query: 1560 SKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQK 1619
                     C  C K + S  +L  H R H GERPY C+ C ++F     L++HQR+H  
Sbjct: 535  K--------CEQCEKGYNSKFNLDMHQRVHGGERPYNCKECGKSFGWASCLLKHQRLHSG 586

Query: 1620 ARHAK 1624
             +  K
Sbjct: 587  EKPLK 591



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 49/228 (21%), Positives = 80/228 (35%), Gaps = 34/228 (14%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F W+S L  H   H+GQK F C++C   F T S    HQ   +G    +    
Sbjct: 396  CKECGKTFRWSSCLLNHQQVHSGQKSFKCEECGKGFYTNSRRSSHQRSHNGEKPYNCEEC 455

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G     +  D+  H    +          G+     S   +         R  +G+ P +
Sbjct: 456  GK-DYKRRLDLEFHQRVHTGERPYNCKECGKSFGWASCLLKHQ-------RLHSGEKPFK 507

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
                        + H     H  E+ +  E+        E+  +S  +LD+         
Sbjct: 508  CEECGKRFTQSSQLHSHQTCHTGEKLYKCEQ-------CEKGYNSKFNLDMH-------- 552

Query: 1428 KLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEP 1475
                   +   GG    E+   C  CGKSF +   L +H++ H  ++P
Sbjct: 553  -------QRVHGG----ERPYNCKECGKSFGWASCLLKHQRLHSGEKP 589



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 12/101 (11%)

Query: 38  QGIKSPSKPPGPNRIGRRNQETKEEKSS---------YNCPLCEKICTTQHQLTMHIRQH 88
           Q + S  KP      G+R  ++ +  S          Y C  CEK   ++  L MH R H
Sbjct: 497 QRLHSGEKPFKCEECGKRFTQSSQLHSHQTCHTGEKLYKCEQCEKGYNSKFNLDMHQRVH 556

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTV 129
               G   ++C  CGKS   AS L +H  +HSGE+P K  V
Sbjct: 557 G---GERPYNCKECGKSFGWASCLLKHQRLHSGEKPLKSGV 594



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 51/239 (21%), Positives = 82/239 (34%), Gaps = 36/239 (15%)

Query: 114 RHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRK 173
           R  + H  ++PY+C  C QSF+       H + H  + +        S      L   ++
Sbjct: 159 RLSISHVQQKPYRCNECKQSFSDVSVFDLHQQSHSGEKSHTCGECGKSFCYSPALHIHQR 218

Query: 174 LSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           +                              ++ + C VC KEF     L+TH   H+ +
Sbjct: 219 VH---------------------------MGEKCYKCDVCGKEFNQSSHLQTHQRVHTGE 251

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFS 290
            P +C  C   F +   L  H  L   + P +    G+ FI ++          G   F 
Sbjct: 252 KPFKCGQCGKGFHSRSALNVHCKLHTGEKPYNCEECGKAFIHDSQLQEHQRIHTGEKPFK 311

Query: 291 CRKFPRISQAWCETNLRRCISEQHR-FVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
           C    +  +     N    +    + F CDTC K F    +L  H   H+     +EKP
Sbjct: 312 CDICGKSFRVRSRLNRHSMVHTGEKPFRCDTCGKNFRQRSALNSHSMVHI-----EEKP 365



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 79/387 (20%), Positives = 121/387 (31%), Gaps = 99/387 (25%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHG-----VTTC 1302
            C  C + F   S LQ H   HTG+KPF C  C   F  +S   RH +   G       TC
Sbjct: 284  CEECGKAFIHDSQLQEHQRIHTGEKPFKCDICGKSFRVRSRLNRHSMVHTGEKPFRCDTC 343

Query: 1303 S---LRRNGLIPQSK-------------------ESDVGSHDSTDSQSDAETAAAAGEVL 1340
                 +R+ L   S                      D   H    +          G+  
Sbjct: 344  GKNFRQRSALNSHSMVHIEEKPYKCEQCGKGFICRRDFCKHQMVHTGEKPYNCKECGKTF 403

Query: 1341 DLTS--RDREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEE 1398
              +S   + +Q   G    +        E+      +   R  H R  SH  E+ +  EE
Sbjct: 404  RWSSCLLNHQQVHSGQKSFK-------CEECGKGFYTNSRRSSHQR--SHNGEKPYNCEE 454

Query: 1399 STGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFK 1458
               D           + LDL+F  ++                  + E+   C  CGKSF 
Sbjct: 455  CGKD---------YKRRLDLEFHQRV-----------------HTGERPYNCKECGKSFG 488

Query: 1459 FLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAP 1518
            +   L +H++ H  ++P           EE  +   +  +                    
Sbjct: 489  WASCLLKHQRLHSGEKP--------FKCEECGKRFTQSSQLHSHQTCHT----------- 529

Query: 1519 AEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWS 1578
             EKL +  +         EK  + K + D   +            +R   C  C K F  
Sbjct: 530  GEKLYKCEQ--------CEKGYNSKFNLDMHQRV--------HGGERPYNCKECGKSFGW 573

Query: 1579 LQDLTRHMRSHTGERPYKCQTCERTFT 1605
               L +H R H+GE+P K    E  ++
Sbjct: 574  ASCLLKHQRLHSGEKPLKSGVWEEIYS 600



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 7/92 (7%)

Query: 607 PLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHL 666
           P   E   K+     +L +  T   G+K       LY C  C + +     L  H R H 
Sbjct: 505 PFKCEECGKRFTQSSQLHSHQTCHTGEK-------LYKCEQCEKGYNSKFNLDMHQRVHG 557

Query: 667 GISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           G  PY C  C       + L++H R HSGE+P
Sbjct: 558 GERPYNCKECGKSFGWASCLLKHQRLHSGEKP 589



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 3/113 (2%)

Query: 1508 VESAPGAG---EAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADK 1564
            +E+ P AG   E   +++ E+          + + SS+   +   P     +   S   +
Sbjct: 108  METVPEAGPHEEWSCQQIWEQIASDLTRSQNSIRNSSQFFKEGDVPCQIEARLSISHVQQ 167

Query: 1565 RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            +   C+ C + F  +     H +SH+GE+ + C  C ++F    +L  HQR+H
Sbjct: 168  KPYRCNECKQSFSDVSVFDLHQQSHSGEKSHTCGECGKSFCYSPALHIHQRVH 220



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 18/45 (40%), Positives = 24/45 (53%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            C  C + F  +S LQ H   HTG+KPF C +C   F ++S    H
Sbjct: 228  CDVCGKEFNQSSHLQTHQRVHTGEKPFKCGQCGKGFHSRSALNVH 272



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S+L  H   HTG+KP+ C++C   F   S  + HQ
Sbjct: 256  CGQCGKGFHSRSALNVHCKLHTGEKPYNCEECGKAFIHDSQLQEHQ 301



 Score = 37.7 bits (86), Expect = 0.098
 Identities = 15/47 (31%), Positives = 24/47 (51%)

Query: 1247 TCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            TC  C + F ++ +L  H   H G+K + C  C   F+  S+ + HQ
Sbjct: 199  TCGECGKSFCYSPALHIHQRVHMGEKCYKCDVCGKEFNQSSHLQTHQ 245


>gi|157952211 zinc finger protein 250 isoform b [Homo sapiens]
          Length = 555

 Score =  104 bits (259), Expect = 9e-22
 Identities = 86/322 (26%), Positives = 133/322 (41%), Gaps = 43/322 (13%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  Y C  C K       L  H R H   TG   + CS+CGK+ S +S L +H
Sbjct: 184 HQAVPSGERPYMCVECGKCFGRSSHLLQHQRIH---TGEKPYVCSVCGKAFSQSSVLSKH 240

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
             +H+GE+PY+C  CG++F  + ++ +H KIH       T   P   L+ R+  +  +LS
Sbjct: 241 RRIHTGEKPYECNECGKAFRVSSDLAQHHKIH-------TGEKPHECLECRKAFT--QLS 291

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNP 234
           H  + +R         +  G         +  + CP+C K F     L +H   H+ + P
Sbjct: 292 HLIQHQR---------IHTG---------ERPYVCPLCGKAFNHSTVLRSHQRVHTGEKP 333

Query: 235 LRCDICCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            RC+ C  TF   R LL+H  +   + P      G+ F   +  I       G   + C 
Sbjct: 334 HRCNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECS 393

Query: 293 KFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQAT 351
           +  +  S      N  R  +E+  + C  C KAF     L  H++ H       EKP   
Sbjct: 394 ECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTG-----EKPYVC 448

Query: 352 PLPGDALDQKGFLALLGLQHTK 373
              G A   +  L    +QH +
Sbjct: 449 GECGHAFSARRSL----IQHER 466



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 60/218 (27%), Positives = 90/218 (41%), Gaps = 22/218 (10%)

Query: 605 LLPLSMEAKIKQEITEG-ELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVR 663
           L P S++ +  Q +++   L      P G++        Y C  C + F  S  L  H R
Sbjct: 162 LSPNSVDHREVQVLSQSMPLTPHQAVPSGERP-------YMCVECGKCFGRSSHLLQHQR 214

Query: 664 SHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHL 723
            H G  PY C++C    +  + L +H R H+GE+PY C  C   F V ++  +H +    
Sbjct: 215 IHTGEKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTG 274

Query: 724 KATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGEDLKHYRALRIHMRTHCGRGLG 781
           +   + +E    +   S           +   VC LCG+   H   LR H R        
Sbjct: 275 EKPHECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRV------- 327

Query: 782 GGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
             H G KP  C EC   F+ KR  + H   Q +H  E+
Sbjct: 328 --HTGEKPHRCNECGKTFSVKRTLLQH---QRIHTGEK 360



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 81/317 (25%), Positives = 122/317 (38%), Gaps = 25/317 (7%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K       L  H   H   TG   H C  C K+ +  S L +H  +H+GERPY
Sbjct: 250 YECNECGKAFRVSSDLAQH---HKIHTGEKPHECLECRKAFTQLSHLIQHQRIHTGERPY 306

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKD-PNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
            C +CG++F  +  +  H ++H  + P+          +KR  L  +R   H  E     
Sbjct: 307 VCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQR--IHTGEKPYTC 364

Query: 185 PAPAKKMVEDG---QSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDN-PLRCDIC 240
               K   +     Q  ++    ++ + C  C K F  +  L  H   H++  P  C  C
Sbjct: 365 SECGKAFSDRSVLIQHHNVHT-GEKPYECSECGKTFSHRSTLMNHERIHTEEKPYACYEC 423

Query: 241 CVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRIS 298
              F  H  L++H  +   + P      G  F      I       G   F C +  +  
Sbjct: 424 GKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAF 483

Query: 299 --QAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGD 356
             +A    +LR    E+  + C++C KAF     L  H++ H       EKP      G 
Sbjct: 484 SLKATLIVHLRTHTGEKP-YECNSCGKAFSQYSVLIQHQRIHTG-----EKPYECGECGR 537

Query: 357 ALDQKGFLALLGLQHTK 373
           A +Q G L    +QH K
Sbjct: 538 AFNQHGHL----IQHQK 550



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 56/199 (28%), Positives = 81/199 (40%), Gaps = 48/199 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S VLR+H R H G  P++CN C    + K  L++H R H+GE+PY C 
Sbjct: 306 YVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQRIHTGEKPYTCS 365

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ ++   +H    ++    K  E                       C  CG+  
Sbjct: 366 ECGKAFSDRSVLIQH---HNVHTGEKPYE-----------------------CSECGKTF 399

Query: 763 KHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAFAAKR 803
            H   L  H R H          CG+              H G KP+ C EC  AF+A+R
Sbjct: 400 SHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARR 459

Query: 804 NCIHHILKQHLHVPEQDIE 822
           + I H   + +H  E+  +
Sbjct: 460 SLIQH---ERIHTGEKPFQ 475



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 52/168 (30%), Positives = 71/168 (42%), Gaps = 13/168 (7%)

Query: 645 CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKIC 704
           C  C + F+    L  H R H G  PY C+ C    +D++ LI+H   H+GE+PY C  C
Sbjct: 336 CNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSEC 395

Query: 705 HYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSS---AAELVDAFCAPDTVCRLCGED 761
              F+ ++    H R    +      E    +V  S     + V     P  VC  CG  
Sbjct: 396 GKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKP-YVCGECGHA 454

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHI 809
               R+L  H R          H G KPF+C EC  AF+ K   I H+
Sbjct: 455 FSARRSLIQHERI---------HTGEKPFQCTECGKAFSLKATLIVHL 493



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 49/170 (28%), Positives = 69/170 (40%), Gaps = 15/170 (8%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H    PY C  C       + LI+H R H+GE+PY+C 
Sbjct: 390 YECSECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCG 449

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C + F+ + +  +H R    +K  + T  +  K     ++    L          C  C
Sbjct: 450 ECGHAFSARRSLIQHERIHTGEKPFQCT--ECGKAFSLKATLIVHLRTHTGEKPYECNSC 507

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           G+    Y  L  H R          H G KP+EC EC  AF    + I H
Sbjct: 508 GKAFSQYSVLIQHQRI---------HTGEKPYECGECGRAFNQHGHLIQH 548



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 31/84 (36%), Positives = 51/84 (60%), Gaps = 3/84 (3%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           + C  C K  + +  L +H+R H   TG   + C+ CGK+ S  S L +H  +H+GE+PY
Sbjct: 474 FQCTECGKAFSLKATLIVHLRTH---TGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPY 530

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEK 149
           +C  CG++F  +G++ +H K+H K
Sbjct: 531 ECGECGRAFNQHGHLIQHQKVHRK 554



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 21/198 (10%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD--EKGDGASTAEEGPQPAPEQEEKPPE 1502
            E+   C  CGK+F     LS+HR+ H  ++P +  E G     + +  Q       + P 
Sbjct: 219  EKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPH 278

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGP-------SDGESAAEKRSSEKSDDDKKP----- 1550
               E  ++          +     E P            +   RS ++    +KP     
Sbjct: 279  ECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNE 338

Query: 1551 --KTDSPKSVASKADK-----RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERT 1603
              KT S K    +  +     +   CS C K F     L +H   HTGE+PY+C  C +T
Sbjct: 339  CGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKT 398

Query: 1604 FTLKHSLVRHQRIHQKAR 1621
            F+ + +L+ H+RIH + +
Sbjct: 399  FSHRSTLMNHERIHTEEK 416



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 1/82 (1%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H+R+H G  PY+CN C    +  + LI+H R H+GE+PY C 
Sbjct: 474 FQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECG 533

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F    +  +H +K H K
Sbjct: 534 ECGRAFNQHGHLIQH-QKVHRK 554



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 62  EKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSG 121
           E+  Y C  C K       L  H R H   TG   + C  CG + S+  SL +H  +H+G
Sbjct: 414 EEKPYACYECGKAFVQHSHLIQHQRVH---TGEKPYVCGECGHAFSARRSLIQHERIHTG 470

Query: 122 ERPYKCTVCGQSFTTNGNMHRHMKIH 147
           E+P++CT CG++F+    +  H++ H
Sbjct: 471 EKPFQCTECGKAFSLKATLIVHLRTH 496



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 49/196 (25%), Positives = 81/196 (41%), Gaps = 21/196 (10%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQ--EEKPPE 1502
            E+   C  CGK+F     L +H   H  ++P +    G + +        E+   E+ P 
Sbjct: 359  EKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTEEKPY 418

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGP----SDGESAAEKRS---SEKSDDDKKPK--TD 1553
               E  ++          +     E P      G + + +RS    E+    +KP   T+
Sbjct: 419  ACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTE 478

Query: 1554 SPKSVASKAD----------KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERT 1603
              K+ + KA           ++   C+ C K F     L +H R HTGE+PY+C  C R 
Sbjct: 479  CGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRA 538

Query: 1604 FTLKHSLVRHQRIHQK 1619
            F     L++HQ++H+K
Sbjct: 539  FNQHGHLIQHQKVHRK 554



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 3/93 (3%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++Q     +  Y C  C    + +  L  H R H   TG     C+ CGK+ S  ++L  
Sbjct: 435 QHQRVHTGEKPYVCGECGHAFSARRSLIQHERIH---TGEKPFQCTECGKAFSLKATLIV 491

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147
           H+  H+GE+PY+C  CG++F+    + +H +IH
Sbjct: 492 HLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIH 524



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 26/62 (41%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C  C K F  L  L +H R HTGERPY C  C + F     L  HQR+H  +K       
Sbjct: 280  CLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNEC 339

Query: 1627 GK 1628
            GK
Sbjct: 340  GK 341



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 23/59 (38%), Positives = 32/59 (54%)

Query: 1559 ASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            A  + +R  +C  C K F     L +H R HTGE+PY C  C + F+    L +H+RIH
Sbjct: 186  AVPSGERPYMCVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHRRIH 244



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 18/46 (39%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            CP C + F  ++ L+ H   HTG+KP  C +C   FS K    +HQ
Sbjct: 308  CPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQ 353



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 18/47 (38%), Positives = 25/47 (53%)

Query: 1247 TCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            TC  C + F   S L +H   HTG+KP+ C +C   FS +S    H+
Sbjct: 363  TCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHE 409



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 18/46 (39%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   ++L  H+ THTG+KP+ C  C   FS  S   +HQ
Sbjct: 476  CTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQ 521



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 16/45 (35%), Positives = 24/45 (53%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            C  C + F  +S L +H   HTG+KP+ C +C   F   S+  +H
Sbjct: 224  CSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQH 268



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH 1297
            C  C   F    SL +H   HTG+KPF C +C   FS K+    H LR H
Sbjct: 448  CGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVH-LRTH 496



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F  +S L +H   HTG+KP+ C  C   FS  S   +H+
Sbjct: 196  CVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHR 241



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 47/228 (20%), Positives = 77/228 (33%), Gaps = 34/228 (14%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F    +L +H   HTG+KP+ C +C   FS +S   +H     G         
Sbjct: 336  CNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSEC 395

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G    S  S + +H+   ++         G+     S   +       E   V G+    
Sbjct: 396  GK-TFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGEC--G 452

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
             A +   S +  E    GE      E G   S                     AT ++  
Sbjct: 453  HAFSARRSLIQHERIHTGEKPFQCTECGKAFSLK-------------------ATLIVHL 493

Query: 1428 KLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEP 1475
            +   G            E+   C++CGK+F     L +H++ H  ++P
Sbjct: 494  RTHTG------------EKPYECNSCGKAFSQYSVLIQHQRIHTGEKP 529



 Score = 39.7 bits (91), Expect = 0.026
 Identities = 17/46 (36%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F  +S L +H   HTG+KP  C +C   F+  S+  +HQ
Sbjct: 252  CNECGKAFRVSSDLAQHHKIHTGEKPHECLECRKAFTQLSHLIQHQ 297



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 17/36 (47%), Positives = 21/36 (58%)

Query: 1582 LTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            LT H    +GERPY C  C + F     L++HQRIH
Sbjct: 181  LTPHQAVPSGERPYMCVECGKCFGRSSHLLQHQRIH 216



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S L +H   HTG+KP+ C +C   F+   +  +HQ
Sbjct: 504  CNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQ 549



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 15/46 (32%), Positives = 22/46 (47%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S L +H   HTG++P+ C  C   F+  +    HQ
Sbjct: 280  CLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQ 325


>gi|45387947 zinc finger protein 250 isoform a [Homo sapiens]
          Length = 560

 Score =  104 bits (259), Expect = 9e-22
 Identities = 86/322 (26%), Positives = 133/322 (41%), Gaps = 43/322 (13%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  Y C  C K       L  H R H   TG   + CS+CGK+ S +S L +H
Sbjct: 189 HQAVPSGERPYMCVECGKCFGRSSHLLQHQRIH---TGEKPYVCSVCGKAFSQSSVLSKH 245

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
             +H+GE+PY+C  CG++F  + ++ +H KIH       T   P   L+ R+  +  +LS
Sbjct: 246 RRIHTGEKPYECNECGKAFRVSSDLAQHHKIH-------TGEKPHECLECRKAFT--QLS 296

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNP 234
           H  + +R         +  G         +  + CP+C K F     L +H   H+ + P
Sbjct: 297 HLIQHQR---------IHTG---------ERPYVCPLCGKAFNHSTVLRSHQRVHTGEKP 338

Query: 235 LRCDICCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCR 292
            RC+ C  TF   R LL+H  +   + P      G+ F   +  I       G   + C 
Sbjct: 339 HRCNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECS 398

Query: 293 KFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQAT 351
           +  +  S      N  R  +E+  + C  C KAF     L  H++ H       EKP   
Sbjct: 399 ECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTG-----EKPYVC 453

Query: 352 PLPGDALDQKGFLALLGLQHTK 373
              G A   +  L    +QH +
Sbjct: 454 GECGHAFSARRSL----IQHER 471



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 60/218 (27%), Positives = 90/218 (41%), Gaps = 22/218 (10%)

Query: 605 LLPLSMEAKIKQEITEG-ELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVR 663
           L P S++ +  Q +++   L      P G++        Y C  C + F  S  L  H R
Sbjct: 167 LSPNSVDHREVQVLSQSMPLTPHQAVPSGERP-------YMCVECGKCFGRSSHLLQHQR 219

Query: 664 SHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHL 723
            H G  PY C++C    +  + L +H R H+GE+PY C  C   F V ++  +H +    
Sbjct: 220 IHTGEKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTG 279

Query: 724 KATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGEDLKHYRALRIHMRTHCGRGLG 781
           +   + +E    +   S           +   VC LCG+   H   LR H R        
Sbjct: 280 EKPHECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRV------- 332

Query: 782 GGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
             H G KP  C EC   F+ KR  + H   Q +H  E+
Sbjct: 333 --HTGEKPHRCNECGKTFSVKRTLLQH---QRIHTGEK 365



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 81/317 (25%), Positives = 122/317 (38%), Gaps = 25/317 (7%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K       L  H   H   TG   H C  C K+ +  S L +H  +H+GERPY
Sbjct: 255 YECNECGKAFRVSSDLAQH---HKIHTGEKPHECLECRKAFTQLSHLIQHQRIHTGERPY 311

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKD-PNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
            C +CG++F  +  +  H ++H  + P+          +KR  L  +R   H  E     
Sbjct: 312 VCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQR--IHTGEKPYTC 369

Query: 185 PAPAKKMVEDG---QSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDN-PLRCDIC 240
               K   +     Q  ++    ++ + C  C K F  +  L  H   H++  P  C  C
Sbjct: 370 SECGKAFSDRSVLIQHHNVHT-GEKPYECSECGKTFSHRSTLMNHERIHTEEKPYACYEC 428

Query: 241 CVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRIS 298
              F  H  L++H  +   + P      G  F      I       G   F C +  +  
Sbjct: 429 GKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAF 488

Query: 299 --QAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGD 356
             +A    +LR    E+  + C++C KAF     L  H++ H       EKP      G 
Sbjct: 489 SLKATLIVHLRTHTGEKP-YECNSCGKAFSQYSVLIQHQRIHTG-----EKPYECGECGR 542

Query: 357 ALDQKGFLALLGLQHTK 373
           A +Q G L    +QH K
Sbjct: 543 AFNQHGHL----IQHQK 555



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 56/199 (28%), Positives = 81/199 (40%), Gaps = 48/199 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S VLR+H R H G  P++CN C    + K  L++H R H+GE+PY C 
Sbjct: 311 YVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQRIHTGEKPYTCS 370

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ ++   +H    ++    K  E                       C  CG+  
Sbjct: 371 ECGKAFSDRSVLIQH---HNVHTGEKPYE-----------------------CSECGKTF 404

Query: 763 KHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAFAAKR 803
            H   L  H R H          CG+              H G KP+ C EC  AF+A+R
Sbjct: 405 SHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARR 464

Query: 804 NCIHHILKQHLHVPEQDIE 822
           + I H   + +H  E+  +
Sbjct: 465 SLIQH---ERIHTGEKPFQ 480



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 52/168 (30%), Positives = 71/168 (42%), Gaps = 13/168 (7%)

Query: 645 CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKIC 704
           C  C + F+    L  H R H G  PY C+ C    +D++ LI+H   H+GE+PY C  C
Sbjct: 341 CNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSEC 400

Query: 705 HYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSS---AAELVDAFCAPDTVCRLCGED 761
              F+ ++    H R    +      E    +V  S     + V     P  VC  CG  
Sbjct: 401 GKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKP-YVCGECGHA 459

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHI 809
               R+L  H R          H G KPF+C EC  AF+ K   I H+
Sbjct: 460 FSARRSLIQHERI---------HTGEKPFQCTECGKAFSLKATLIVHL 498



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 49/170 (28%), Positives = 69/170 (40%), Gaps = 15/170 (8%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H    PY C  C       + LI+H R H+GE+PY+C 
Sbjct: 395 YECSECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCG 454

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C + F+ + +  +H R    +K  + T  +  K     ++    L          C  C
Sbjct: 455 ECGHAFSARRSLIQHERIHTGEKPFQCT--ECGKAFSLKATLIVHLRTHTGEKPYECNSC 512

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           G+    Y  L  H R          H G KP+EC EC  AF    + I H
Sbjct: 513 GKAFSQYSVLIQHQRI---------HTGEKPYECGECGRAFNQHGHLIQH 553



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 31/84 (36%), Positives = 51/84 (60%), Gaps = 3/84 (3%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           + C  C K  + +  L +H+R H   TG   + C+ CGK+ S  S L +H  +H+GE+PY
Sbjct: 479 FQCTECGKAFSLKATLIVHLRTH---TGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPY 535

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEK 149
           +C  CG++F  +G++ +H K+H K
Sbjct: 536 ECGECGRAFNQHGHLIQHQKVHRK 559



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 49/198 (24%), Positives = 80/198 (40%), Gaps = 21/198 (10%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD--EKGDGASTAEEGPQPAPEQEEKPPE 1502
            E+   C  CGK+F     LS+HR+ H  ++P +  E G     + +  Q       + P 
Sbjct: 224  EKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPH 283

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGP-------SDGESAAEKRSSEKSDDDKKP----- 1550
               E  ++          +     E P            +   RS ++    +KP     
Sbjct: 284  ECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNE 343

Query: 1551 --KTDSPKSVASKADK-----RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERT 1603
              KT S K    +  +     +   CS C K F     L +H   HTGE+PY+C  C +T
Sbjct: 344  CGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKT 403

Query: 1604 FTLKHSLVRHQRIHQKAR 1621
            F+ + +L+ H+RIH + +
Sbjct: 404  FSHRSTLMNHERIHTEEK 421



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 1/82 (1%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H+R+H G  PY+CN C    +  + LI+H R H+GE+PY C 
Sbjct: 479 FQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECG 538

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F    +  +H +K H K
Sbjct: 539 ECGRAFNQHGHLIQH-QKVHRK 559



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query: 62  EKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSG 121
           E+  Y C  C K       L  H R H   TG   + C  CG + S+  SL +H  +H+G
Sbjct: 419 EEKPYACYECGKAFVQHSHLIQHQRVH---TGEKPYVCGECGHAFSARRSLIQHERIHTG 475

Query: 122 ERPYKCTVCGQSFTTNGNMHRHMKIH 147
           E+P++CT CG++F+    +  H++ H
Sbjct: 476 EKPFQCTECGKAFSLKATLIVHLRTH 501



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 49/196 (25%), Positives = 81/196 (41%), Gaps = 21/196 (10%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQ--EEKPPE 1502
            E+   C  CGK+F     L +H   H  ++P +    G + +        E+   E+ P 
Sbjct: 364  EKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTEEKPY 423

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGP----SDGESAAEKRS---SEKSDDDKKPK--TD 1553
               E  ++          +     E P      G + + +RS    E+    +KP   T+
Sbjct: 424  ACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTE 483

Query: 1554 SPKSVASKAD----------KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERT 1603
              K+ + KA           ++   C+ C K F     L +H R HTGE+PY+C  C R 
Sbjct: 484  CGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRA 543

Query: 1604 FTLKHSLVRHQRIHQK 1619
            F     L++HQ++H+K
Sbjct: 544  FNQHGHLIQHQKVHRK 559



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 3/93 (3%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++Q     +  Y C  C    + +  L  H R H   TG     C+ CGK+ S  ++L  
Sbjct: 440 QHQRVHTGEKPYVCGECGHAFSARRSLIQHERIH---TGEKPFQCTECGKAFSLKATLIV 496

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147
           H+  H+GE+PY+C  CG++F+    + +H +IH
Sbjct: 497 HLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIH 529



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 26/62 (41%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C  C K F  L  L +H R HTGERPY C  C + F     L  HQR+H  +K       
Sbjct: 285  CLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNEC 344

Query: 1627 GK 1628
            GK
Sbjct: 345  GK 346



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 23/59 (38%), Positives = 32/59 (54%)

Query: 1559 ASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            A  + +R  +C  C K F     L +H R HTGE+PY C  C + F+    L +H+RIH
Sbjct: 191  AVPSGERPYMCVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHRRIH 249



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 18/46 (39%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            CP C + F  ++ L+ H   HTG+KP  C +C   FS K    +HQ
Sbjct: 313  CPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQ 358



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 18/47 (38%), Positives = 25/47 (53%)

Query: 1247 TCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            TC  C + F   S L +H   HTG+KP+ C +C   FS +S    H+
Sbjct: 368  TCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHE 414



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 18/46 (39%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   ++L  H+ THTG+KP+ C  C   FS  S   +HQ
Sbjct: 481  CTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQ 526



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 16/45 (35%), Positives = 24/45 (53%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            C  C + F  +S L +H   HTG+KP+ C +C   F   S+  +H
Sbjct: 229  CSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQH 273



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH 1297
            C  C   F    SL +H   HTG+KPF C +C   FS K+    H LR H
Sbjct: 453  CGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVH-LRTH 501



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F  +S L +H   HTG+KP+ C  C   FS  S   +H+
Sbjct: 201  CVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHR 246



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 47/228 (20%), Positives = 77/228 (33%), Gaps = 34/228 (14%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F    +L +H   HTG+KP+ C +C   FS +S   +H     G         
Sbjct: 341  CNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSEC 400

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G    S  S + +H+   ++         G+     S   +       E   V G+    
Sbjct: 401  GK-TFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGEC--G 457

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
             A +   S +  E    GE      E G   S                     AT ++  
Sbjct: 458  HAFSARRSLIQHERIHTGEKPFQCTECGKAFSLK-------------------ATLIVHL 498

Query: 1428 KLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEP 1475
            +   G            E+   C++CGK+F     L +H++ H  ++P
Sbjct: 499  RTHTG------------EKPYECNSCGKAFSQYSVLIQHQRIHTGEKP 534



 Score = 39.7 bits (91), Expect = 0.026
 Identities = 17/46 (36%), Positives = 25/46 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F  +S L +H   HTG+KP  C +C   F+  S+  +HQ
Sbjct: 257  CNECGKAFRVSSDLAQHHKIHTGEKPHECLECRKAFTQLSHLIQHQ 302



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 17/36 (47%), Positives = 21/36 (58%)

Query: 1582 LTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            LT H    +GERPY C  C + F     L++HQRIH
Sbjct: 186  LTPHQAVPSGERPYMCVECGKCFGRSSHLLQHQRIH 221



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S L +H   HTG+KP+ C +C   F+   +  +HQ
Sbjct: 509  CNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQ 554



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 15/46 (32%), Positives = 22/46 (47%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S L +H   HTG++P+ C  C   F+  +    HQ
Sbjct: 285  CLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQ 330


>gi|194018469 zinc finger protein 546 [Homo sapiens]
          Length = 836

 Score =  104 bits (259), Expect = 9e-22
 Identities = 78/290 (26%), Positives = 126/290 (43%), Gaps = 17/290 (5%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C +C K    Q  ++ H + H   TG   + C+ CGK+ S  S L +H  +H+GE+PY
Sbjct: 357 YECKVCGKTFRVQRHISQHQKIH---TGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPY 413

Query: 126 KCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           +C  CG+SF+ +  + RH +IH  + P           L+       R  +H  E   E 
Sbjct: 414 ECKECGKSFSFHAELARHRRIHTGEKPYECRECGKAFRLQTELTRHHR--THTGEKPYEC 471

Query: 185 PAPAKKMVEDGQ-SGDLEKKADEV-FHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
               K  +   Q +  L     E+ + C  C K F  +Y L  H   H+ + P  C+ C 
Sbjct: 472 KECGKAFICGYQLTLHLRTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECG 531

Query: 242 VTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRI-S 298
             FR    L RH+ +   + P +    G+ FI +N  I         + + C++  +I S
Sbjct: 532 KAFRLQGELTRHHRIHTCEKPYECKECGKAFIHSNQFISHQRIHTSESTYICKECGKIFS 591

Query: 299 QAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
           + +  T   +  + +  ++C+ C KAF     L  H + H       EKP
Sbjct: 592 RRYNLTQHFKIHTGEKPYICNECGKAFRFQTELTQHHRIHTG-----EKP 636



 Score =  100 bits (249), Expect = 1e-20
 Identities = 72/288 (25%), Positives = 120/288 (41%), Gaps = 34/288 (11%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           R+  T   +  Y C  C K     +QLT+H+R H   TG   + C  CGK+ SS   L +
Sbjct: 458 RHHRTHTGEKPYECKECGKAFICGYQLTLHLRTH---TGEIPYECKECGKTFSSRYHLTQ 514

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKL 174
           H  +H+GE+PY C  CG++F   G + RH +IH  +          + +   +  S +++
Sbjct: 515 HYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYECKECGKAFIHSNQFISHQRI 574

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DN 233
            H +ES                           + C  C K F  +Y L  H + H+ + 
Sbjct: 575 -HTSES--------------------------TYICKECGKIFSRRYNLTQHFKIHTGEK 607

Query: 234 PLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSC 291
           P  C+ C   FR    L +H+ +   + P      G+ FI++           G   + C
Sbjct: 608 PYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKPYEC 667

Query: 292 RKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
            +  +  S+ +  T   R  + +  ++C+ C  AF     L LH++ H
Sbjct: 668 TECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICSYRLTLHQRIH 715



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 81/326 (24%), Positives = 120/326 (36%), Gaps = 48/326 (14%)

Query: 63  KSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGE 122
           + SY C  C K    Q  L  H+R H   TG   + C  CGK+      L  H  +H+GE
Sbjct: 214 EKSYECKECRKAFRQQSYLIQHLRIH---TGERPYKCMECGKAFCRVGDLRVHHTIHAGE 270

Query: 123 RPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESER 182
           RPY+C  CG++F  + ++  H +IH                           S     E 
Sbjct: 271 RPYECKECGKAFRLHYHLTEHQRIH---------------------------SGVKPYEC 303

Query: 183 EDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICC 241
           ++   A   V D +        +  + C  C K F   Y L  H   H+ + P  C +C 
Sbjct: 304 KECGKAFSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCG 363

Query: 242 VTFRTHRGLLRHNALVH---KQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRIS 298
            TFR  R + +H   +H   K    +  G+ F   +  +       G   + C++  +  
Sbjct: 364 KTFRVQRHISQHQK-IHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSF 422

Query: 299 QAWCE-TNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDA 357
               E    RR  + +  + C  C KAF +   L  H +TH       EKP      G A
Sbjct: 423 SFHAELARHRRIHTGEKPYECRECGKAFRLQTELTRHHRTHTG-----EKPYECKECGKA 477

Query: 358 LDQKGFLALLGLQHTKDVRPAPAEEP 383
                   + G Q T  +R    E P
Sbjct: 478 F-------ICGYQLTLHLRTHTGEIP 496



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 73/291 (25%), Positives = 119/291 (40%), Gaps = 34/291 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +S+Y C  C KI + ++ LT H + H   TG   + C+ CGK+    + L +H
Sbjct: 571 HQRIHTSESTYICKECGKIFSRRYNLTQHFKIH---TGEKPYICNECGKAFRFQTELTQH 627

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
             +H+GE+PYKCT CG++F  + ++ +H +IH       T   P    +  +  S+    
Sbjct: 628 HRIHTGEKPYKCTECGKAFIRSTHLTQHHRIH-------TGEKPYECTECGKTFSRHY-- 678

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDN-P 234
           H  +  R            G +G+      + + C  C   F+C Y L  H   H+   P
Sbjct: 679 HLTQHHR------------GHTGE------KPYICNECGNAFICSYRLTLHQRIHTGELP 720

Query: 235 LRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSCR 292
             C  C  TF     L +H  L   + P      G  F              G   + C+
Sbjct: 721 YECKECGKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKPYKCK 780

Query: 293 KFPRISQAWCE-TNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAAD 342
           +  +      E T   R  + +  + C  C KAF     L LH++ H++ +
Sbjct: 781 ECGKAFSVNSELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQRNHISEE 831



 Score = 84.3 bits (207), Expect = 9e-16
 Identities = 50/175 (28%), Positives = 70/175 (40%), Gaps = 35/175 (20%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C + F     +  H + H G+ PY+CN C    +  + L++H + H+GE+PY CK
Sbjct: 357 YECKVCGKTFRVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECK 416

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+  A   RH R   +    K  E                       CR CG+  
Sbjct: 417 ECGKSFSFHAELARHRR---IHTGEKPYE-----------------------CRECGKAF 450

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVP 817
           +    L  H RTH G          KP+ECKEC  AF        H+      +P
Sbjct: 451 RLQTELTRHHRTHTGE---------KPYECKECGKAFICGYQLTLHLRTHTGEIP 496



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 52/205 (25%), Positives = 80/205 (39%), Gaps = 32/205 (15%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C + F     L  H+R+H G  PY+C  C    + +  L +H R H+GE+PYIC 
Sbjct: 469 YECKECGKAFICGYQLTLHLRTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICN 528

Query: 703 ICHYPFTVKANCERHLR------KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F ++    RH R          K   K    + +++S       ++      +C+
Sbjct: 529 ECGKAFRLQGELTRHHRIHTCEKPYECKECGKAFIHSNQFISHQRIHTSES----TYICK 584

Query: 757 LCGEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSA 797
            CG+       L  H + H          CG+              H G KP++C EC  
Sbjct: 585 ECGKIFSRRYNLTQHFKIHTGEKPYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGK 644

Query: 798 AFAAKRNCIHHILKQHLHVPEQDIE 822
           AF    +   H     +H  E+  E
Sbjct: 645 AFIRSTHLTQH---HRIHTGEKPYE 666



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 55/221 (24%), Positives = 81/221 (36%), Gaps = 55/221 (24%)

Query: 621 GELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIA 680
           G+L+   T   G++        Y C+ C + F     L  H R H G+ PY+C  C    
Sbjct: 258 GDLRVHHTIHAGERP-------YECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAF 310

Query: 681 ADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSS 740
           +    L  H   H+GERPY CK C   F +      H R   +    +  E         
Sbjct: 311 SRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQR---IHTGERPYE--------- 358

Query: 741 AAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTH----------CGRGLGGG------- 783
                         C++CG+  +  R +  H + H          CG+    G       
Sbjct: 359 --------------CKVCGKTFRVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQHQ 404

Query: 784 --HKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
             H G KP+ECKEC  +F+       H   + +H  E+  E
Sbjct: 405 KIHTGEKPYECKECGKSFSFHAELARH---RRIHTGEKPYE 442



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 53/187 (28%), Positives = 70/187 (37%), Gaps = 38/187 (20%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           R+  Y C+ C + F     L  H+R H G  PY+C  C         L  H   H+GERP
Sbjct: 213 REKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTIHAGERP 272

Query: 699 YICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
           Y CK C   F +  +   H R   + +  K  E                       C+ C
Sbjct: 273 YECKECGKAFRLHYHLTEHQR---IHSGVKPYE-----------------------CKEC 306

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPE 818
           G+     R LR+H   H          G +P+ECKEC  AF        H   Q +H  E
Sbjct: 307 GKAFSRVRDLRVHQTIHA---------GERPYECKECGKAFRLHYQLTEH---QRIHTGE 354

Query: 819 QDIESYV 825
           +  E  V
Sbjct: 355 RPYECKV 361



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 52/177 (29%), Positives = 68/177 (38%), Gaps = 38/177 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C   F  S  L  H R H G  PY+C  C    + +  L +H R H+GE+PY CK
Sbjct: 693 YICNECGNAFICSYRLTLHQRIHTGELPYECKECGKTFSRRYHLTQHFRLHTGEKPYSCK 752

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F ++A   RH    H+  T +   K                      C+ CG+  
Sbjct: 753 ECGNAFRLQAELTRH----HIVHTGEKPYK----------------------CKECGKAF 786

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
                L  H R H G          KP++CKEC  AF        H   Q  H+ E+
Sbjct: 787 SVNSELTRHHRIHTGE---------KPYQCKECGKAFIRSDQLTLH---QRNHISEE 831



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 55/176 (31%), Positives = 71/176 (40%), Gaps = 38/176 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y CR C + F     L  H R+H G  PY+C  C         L  HLRTH+GE PY CK
Sbjct: 441 YECRECGKAFRLQTELTRHHRTHTGEKPYECKECGKAFICGYQLTLHLRTHTGEIPYECK 500

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ + +  +H R   +    K       Y+ +   +   AF       RL GE  
Sbjct: 501 ECGKTFSSRYHLTQHYR---IHTGEK------PYICNECGK---AF-------RLQGELT 541

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPE 818
           +H+R                 H   KP+ECKEC  AF      I H   Q +H  E
Sbjct: 542 RHHRI----------------HTCEKPYECKECGKAFIHSNQFISH---QRIHTSE 578



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 99/418 (23%), Positives = 144/418 (34%), Gaps = 66/418 (15%)

Query: 1221 EEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCD 1280
            ++Q S P    + A+  SY        C  C + F   S L +H+  HTG++P+ C +C 
Sbjct: 199  QKQISHPLHPKIHAREKSYE-------CKECRKAFRQQSYLIQHLRIHTGERPYKCMECG 251

Query: 1281 AFFSTKSNCERHQLRKHGVTTCSLRRNGL---IPQSKESDVGSHDSTDSQSDAETAAAAG 1337
              F    +   H     G      +  G    +          H         E   A  
Sbjct: 252  KAFCRVGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFS 311

Query: 1338 EVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHRE--EHGRGESHEPEEEHG 1395
             V DL                  AG+ P E      A  +H +  EH R  + E   E  
Sbjct: 312  RVRDLRVHQTIH-----------AGERPYECKECGKAFRLHYQLTEHQRIHTGERPYEC- 359

Query: 1396 TEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGK 1455
              +  G     +   S +Q +     T +  +K                     C+ CGK
Sbjct: 360  --KVCGKTFRVQRHISQHQKIH----TGVKPYK---------------------CNECGK 392

Query: 1456 SFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAG 1515
            +F     L +H+K H  ++P + K  G S +    + A  +     E P E  E      
Sbjct: 393  AFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHA-ELARHRRIHTGEKPYECRECGK--- 448

Query: 1516 EAPAEKLAEET---EGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVC 1572
               A +L  E         GE   E +   K+       T   ++   +       C  C
Sbjct: 449  ---AFRLQTELTRHHRTHTGEKPYECKECGKAFICGYQLTLHLRTHTGEIPYE---CKEC 502

Query: 1573 NKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHHGK 1628
             K F S   LT+H R HTGE+PY C  C + F L+  L RH RIH  +K    K  GK
Sbjct: 503  GKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYECKECGK 560



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 50/187 (26%), Positives = 68/187 (36%), Gaps = 21/187 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F F   L  H R H G  PY+C  C         L +H R H+GE+PY C 
Sbjct: 609 YICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHTGEKPYECT 668

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F+   +  +H R    +      E    ++ S    L       +    C+ CG+
Sbjct: 669 ECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICSYRLTLHQRIHTGELPYECKECGK 728

Query: 761 DLKHYRALRIHMRTHCG------RGLGGG-------------HKGRKPFECKECSAAFAA 801
                  L  H R H G      +  G               H G KP++CKEC  AF+ 
Sbjct: 729 TFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKPYKCKECGKAFSV 788

Query: 802 KRNCIHH 808
                 H
Sbjct: 789 NSELTRH 795



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 84/377 (22%), Positives = 138/377 (36%), Gaps = 27/377 (7%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L +H   HTG+KP+ C++C   FS  +   RH+    G      R  
Sbjct: 387  CNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECREC 446

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G   +  ++++  H  T +          G+             +    LR   G+ P E
Sbjct: 447  GKAFRL-QTELTRHHRTHTGEKPYECKECGKAFICGY-------QLTLHLRTHTGEIPYE 498

Query: 1368 --QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSL---DLDFAT 1422
              +     +S  H  +H R   H  E+ +   E  G A   + + + +  +   +  +  
Sbjct: 499  CKECGKTFSSRYHLTQHYR--IHTGEKPYICNEC-GKAFRLQGELTRHHRIHTCEKPYEC 555

Query: 1423 KLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKG 1480
            K         +         + E    C  CGK F     L++H K H  ++P   +E G
Sbjct: 556  KECGKAFIHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHFKIHTGEKPYICNECG 615

Query: 1481 DGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRS 1540
                   E  Q          E P +  E   G     +  L +     + GE   E   
Sbjct: 616  KAFRFQTELTQ---HHRIHTGEKPYKCTEC--GKAFIRSTHLTQHHRIHT-GEKPYECTE 669

Query: 1541 SEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTC 1600
              K+       T   +       ++  +C+ C   F     LT H R HTGE PY+C+ C
Sbjct: 670  CGKTFSRHYHLTQHHRG---HTGEKPYICNECGNAFICSYRLTLHQRIHTGELPYECKEC 726

Query: 1601 ERTFTLKHSLVRHQRIH 1617
             +TF+ ++ L +H R+H
Sbjct: 727  GKTFSRRYHLTQHFRLH 743



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 85/415 (20%), Positives = 139/415 (33%), Gaps = 47/415 (11%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F     L+ H   H G++P+ C++C   F    +   HQ    GV     +  
Sbjct: 247  CMECGKAFCRVGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYECKEC 306

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVL----DLTSRDREQPSEGATELRQVAGD 1363
            G    S+  D+  H +  +          G+       LT   R    E   E +     
Sbjct: 307  GKA-FSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKT 365

Query: 1364 APVEQATAET------ASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLD 1417
              V++  ++         P    E G+  SH        +  TG+     ++   + S  
Sbjct: 366  FRVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFH 425

Query: 1418 LDFATKLMDFKLAEGDGEAGAGGAASQ--------------EQKLACDTCGKSFKFLGTL 1463
             + A +       E   E    G A +              E+   C  CGK+F     L
Sbjct: 426  AELA-RHRRIHTGEKPYECRECGKAFRLQTELTRHHRTHTGEKPYECKECGKAFICGYQL 484

Query: 1464 SRHRKAHGRQEPKD--EKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEK 1521
            + H + H  + P +  E G   S+     Q       + P    E  ++    GE     
Sbjct: 485  TLHLRTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHH 544

Query: 1522 LAEETEGPSDGESAAEKR-SSEKSDDDKKPKTDSPKSVASKADK---------------- 1564
                 E P + +   +    S +    ++  T     +  +  K                
Sbjct: 545  RIHTCEKPYECKECGKAFIHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHFKIHT 604

Query: 1565 --RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
              +  +C+ C K F    +LT+H R HTGE+PYKC  C + F     L +H RIH
Sbjct: 605  GEKPYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIH 659



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 3/89 (3%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGK 1628
            C  C K F  ++DL  H   H GERPY+C+ C + F L + L  HQRIH   R   +  K
Sbjct: 303  CKECGKAFSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGER--PYECK 360

Query: 1629 DSDKEERGEED-SENESTHSGNNAVSENE 1656
               K  R +   S+++  H+G      NE
Sbjct: 361  VCGKTFRVQRHISQHQKIHTGVKPYKCNE 389



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C  C   F    +LTRH   HTGE+PYKC+ C + F++   L RH RIH  +K    K  
Sbjct: 751  CKECGNAFRLQAELTRHHIVHTGEKPYKCKECGKAFSVNSELTRHHRIHTGEKPYQCKEC 810

Query: 1627 GK 1628
            GK
Sbjct: 811  GK 812



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 2/62 (3%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C  C K F     LT+H R HTGE+PY C+ C   F L+  L RH  +H  +K    K  
Sbjct: 723  CKECGKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKPYKCKEC 782

Query: 1627 GK 1628
            GK
Sbjct: 783  GK 784



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 23/49 (46%), Positives = 28/49 (57%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            C  C K F    +LTRH R HTGE+PY+C+ C + F     L  HQR H
Sbjct: 779  CKECGKAFSVNSELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQRNH 827



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 31/88 (35%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 1562 ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKAR 1621
            A ++   C  C K F     L +H+R HTGERPYKC  C + F     L  H  IH  A 
Sbjct: 212  AREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTIH--AG 269

Query: 1622 HAKHHGKDSDKEERGEED-SENESTHSG 1648
               +  K+  K  R     +E++  HSG
Sbjct: 270  ERPYECKECGKAFRLHYHLTEHQRIHSG 297



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 14/136 (10%)

Query: 689 HLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAF 748
           H + H+ E+ Y CK C   F  ++   +HLR    +   K +E    +       +    
Sbjct: 207 HPKIHAREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTI 266

Query: 749 CAPDT--VCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCI 806
            A +    C+ CG+  + +  L  H R          H G KP+ECKEC  AF+  R+  
Sbjct: 267 HAGERPYECKECGKAFRLHYHLTEHQRI---------HSGVKPYECKECGKAFSRVRDLR 317

Query: 807 HHILKQHLHVPEQDIE 822
            H   Q +H  E+  E
Sbjct: 318 VH---QTIHAGERPYE 330



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 18/46 (39%), Positives = 25/46 (54%)

Query: 1247 TCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            +C  C   F   + L RH + HTG+KP+ C++C   FS  S   RH
Sbjct: 750  SCKECGNAFRLQAELTRHHIVHTGEKPYKCKECGKAFSVNSELTRH 795



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 1/50 (2%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH 1297
            C  C + F   S L RH   HTG+KP+ C++C   F        HQ R H
Sbjct: 779  CKECGKAFSVNSELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQ-RNH 827



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 15/47 (31%), Positives = 24/47 (51%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQL 1294
            C  C + F     L +H   HTG+KP+ C++C   F  ++   RH +
Sbjct: 723  CKECGKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHI 769



 Score = 35.0 bits (79), Expect = 0.64
 Identities = 13/51 (25%), Positives = 23/51 (45%)

Query: 1242 CLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292
            C +   C  C + F  ++    H   HT +  + C++C   FS + N  +H
Sbjct: 549  CEKPYECKECGKAFIHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQH 599


>gi|156766086 zinc finger protein 600 [Homo sapiens]
          Length = 722

 Score =  104 bits (259), Expect = 9e-22
 Identities = 87/311 (27%), Positives = 129/311 (41%), Gaps = 23/311 (7%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C +C+   T   QL  H R H   TG   + C+ CGK+ S  SSL  H  +H GE+ Y
Sbjct: 330 YKCKVCDTAFTWNSQLARHKRIH---TGEKTYKCNECGKTFSHKSSLVCHHRLHGGEKSY 386

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC VC ++F  N ++ RH +IH     S       +   +    +   L H +    E P
Sbjct: 387 KCKVCDKAFAWNSHLVRHTRIH-----SGGKPYKCNECGKTFGQNSDLLIHKSIHTGEQP 441

Query: 186 ---APAKKMVEDGQSGDLEK---KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCD 238
                 +K+   G + +  K     ++ + C VC K F C   L  H   HS + P +C+
Sbjct: 442 YKYEECEKVFSCGSTLETHKIIHTGEKPYKCKVCDKAFACHSYLAKHTRIHSGEKPYKCN 501

Query: 239 ICCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR 296
            C  TFR    L  H  +   + P   +   + F Q +          G   + C +  +
Sbjct: 502 ECSKTFRLRSYLASHRRVHSGEKPYKCNECSKTFSQRSYLHCHRRLHSGEKPYKCNECGK 561

Query: 297 -ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPG 355
             S      + RR  + +  + C  CDKAF     LA H + H A     EKP      G
Sbjct: 562 TFSHKPSLVHHRRLHTGEKSYKCTVCDKAFVRNSYLARHTRIHTA-----EKPYKCNECG 616

Query: 356 DALDQKGFLAL 366
            A +Q+  L+L
Sbjct: 617 KAFNQQSQLSL 627



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 69/280 (24%), Positives = 111/280 (39%), Gaps = 12/280 (4%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K  +    LT H R H   T    H C+ CGK     S+L  H  +H+GE+PY
Sbjct: 218 YKCNECGKSFSQVSSLTCHRRLH---TAVKSHKCNECGKIFGQNSALVIHKAIHTGEKPY 274

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC  C ++F    N+ RH +IH  +             ++  L S +++ H  E   +  
Sbjct: 275 KCNECDKAFNQQSNLARHRRIHTGEKPYKCEECDKVFSRKSTLESHKRI-HTGEKPYKCK 333

Query: 186 APAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETH-SDNPLRCDICCV 242
                   + Q    ++    ++ + C  C K F  K  L  H   H  +   +C +C  
Sbjct: 334 VCDTAFTWNSQLARHKRIHTGEKTYKCNECGKTFSHKSSLVCHHRLHGGEKSYKCKVCDK 393

Query: 243 TFRTHRGLLRHNALVH---KQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQ 299
            F  +  L+RH   +H   K    +  G+ F QN+  +       G   +   +  ++  
Sbjct: 394 AFAWNSHLVRHTR-IHSGGKPYKCNECGKTFGQNSDLLIHKSIHTGEQPYKYEECEKVFS 452

Query: 300 AWCETNLRRCI-SEQHRFVCDTCDKAFPMLCSLALHKQTH 338
                   + I + +  + C  CDKAF     LA H + H
Sbjct: 453 CGSTLETHKIIHTGEKPYKCKVCDKAFACHSYLAKHTRIH 492



 Score = 88.6 bits (218), Expect = 5e-17
 Identities = 54/187 (28%), Positives = 76/187 (40%), Gaps = 21/187 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C++ F+    L  H R H G  PY+CN C    + K +L+ H R H+GE+ Y C 
Sbjct: 526 YKCNECSKTFSQRSYLHCHRRLHSGEKPYKCNECGKTFSHKPSLVHHRRLHTGEKSYKCT 585

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTV--CRLCGE 760
           +C   F   +   RH R    +   K  E    +   S   L     A + +  C  C +
Sbjct: 586 VCDKAFVRNSYLARHTRIHTAEKPYKCNECGKAFNQQSQLSLHHRIHAGEKLYKCETCDK 645

Query: 761 DLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAAFAA 801
                  L+ H R H          C +  G         G H G KP++C EC  AF+ 
Sbjct: 646 VFSRKSHLKRHRRIHPGKKPYKCKVCDKTFGSDSHLKQHTGLHTGEKPYKCNECGKAFSK 705

Query: 802 KRNCIHH 808
           +   IHH
Sbjct: 706 QSTLIHH 712



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 72/309 (23%), Positives = 118/309 (38%), Gaps = 64/309 (20%)

Query: 63  KSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSL---------------- 106
           + SY C +C+K       L  H R H+   GG  + C+ CGK+                 
Sbjct: 383 EKSYKCKVCDKAFAWNSHLVRHTRIHS---GGKPYKCNECGKTFGQNSDLLIHKSIHTGE 439

Query: 107 ------------SSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSA 154
                       S  S+L+ H ++H+GE+PYKC VC ++F  +  + +H +IH  +    
Sbjct: 440 QPYKYEECEKVFSCGSTLETHKIIHTGEKPYKCKVCDKAFACHSYLAKHTRIHSGE---- 495

Query: 155 TATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCF 214
                  P K    S   +L     S R         V  G+         + + C  C 
Sbjct: 496 ------KPYKCNECSKTFRLRSYLASHRR--------VHSGE---------KPYKCNECS 532

Query: 215 KEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVH---KQLPRDAMGRPF 270
           K F  +  L  H   HS + P +C+ C  TF +H+  L H+  +H   K        + F
Sbjct: 533 KTFSQRSYLHCHRRLHSGEKPYKCNECGKTF-SHKPSLVHHRRLHTGEKSYKCTVCDKAF 591

Query: 271 IQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHR-FVCDTCDKAFPMLC 329
           ++N+              + C +  +      + +L   I    + + C+TCDK F    
Sbjct: 592 VRNSYLARHTRIHTAEKPYKCNECGKAFNQQSQLSLHHRIHAGEKLYKCETCDKVFSRKS 651

Query: 330 SLALHKQTH 338
            L  H++ H
Sbjct: 652 HLKRHRRIH 660



 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 50/166 (30%), Positives = 67/166 (40%), Gaps = 35/166 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C++ F     L  H R H G  PY+C  CD + + K+ L  H R H+GE+PY CK
Sbjct: 274 YKCNECDKAFNQQSNLARHRRIHTGEKPYKCEECDKVFSRKSTLESHKRIHTGEKPYKCK 333

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
           +C   FT  +   RH R    + T K                          C  CG+  
Sbjct: 334 VCDTAFTWNSQLARHKRIHTGEKTYK--------------------------CNECGKTF 367

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            H  +L  H R          H G K ++CK C  AFA   + + H
Sbjct: 368 SHKSSLVCHHRL---------HGGEKSYKCKVCDKAFAWNSHLVRH 404



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 51/183 (27%), Positives = 71/183 (38%), Gaps = 38/183 (20%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y    C +VF+    L  H   H G  PY+C +CD   A  + L +H R HSGE+PY C 
Sbjct: 442 YKYEECEKVFSCGSTLETHKIIHTGEKPYKCKVCDKAFACHSYLAKHTRIHSGEKPYKCN 501

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F +++    H R    +   K                          C  C +  
Sbjct: 502 ECSKTFRLRSYLASHRRVHSGEKPYK--------------------------CNECSKTF 535

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
                L      HC R L   H G KP++C EC   F+ K + +HH   + LH  E+  +
Sbjct: 536 SQRSYL------HCHRRL---HSGEKPYKCNECGKTFSHKPSLVHH---RRLHTGEKSYK 583

Query: 823 SYV 825
             V
Sbjct: 584 CTV 586



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 69/295 (23%), Positives = 115/295 (38%), Gaps = 20/295 (6%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           + QE    + S+ C    K       L  H   H    G   + C +CGK  +    L  
Sbjct: 151 QKQEVYMREKSFQCNESGKAFNCSSLLRKHQIPH---LGDKQYKCDVCGKLFNHKQYLTC 207

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKL 174
           H   H+GE+PYKC  CG+SF+   ++  H ++H     +A  +   +   +    +   +
Sbjct: 208 HRRCHTGEKPYKCNECGKSFSQVSSLTCHRRLH-----TAVKSHKCNECGKIFGQNSALV 262

Query: 175 SHDAESEREDPAPAKKMVED-GQSGDLEK-----KADEVFHCPVCFKEFVCKYGLETHME 228
            H A    E P    +  +   Q  +L +       ++ + C  C K F  K  LE+H  
Sbjct: 263 IHKAIHTGEKPYKCNECDKAFNQQSNLARHRRIHTGEKPYKCEECDKVFSRKSTLESHKR 322

Query: 229 THS-DNPLRCDICCVTFRTHRGLLRHNAL--VHKQLPRDAMGRPFIQNNPSIPAGFHDLG 285
            H+ + P +C +C   F  +  L RH  +    K    +  G+ F   +  +       G
Sbjct: 323 IHTGEKPYKCKVCDTAFTWNSQLARHKRIHTGEKTYKCNECGKTFSHKSSLVCHHRLHGG 382

Query: 286 FTDFSCRKFPRISQAWCETNLR--RCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
              + C+   + + AW    +R  R  S    + C+ C K F     L +HK  H
Sbjct: 383 EKSYKCKVCDK-AFAWNSHLVRHTRIHSGGKPYKCNECGKTFGQNSDLLIHKSIH 436



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 62/228 (27%), Positives = 88/228 (38%), Gaps = 56/228 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C++ FA    L  H R H G  PY+CN C      ++ L  H R HSGE+PY C 
Sbjct: 470 YKCKVCDKAFACHSYLAKHTRIHSGEKPYKCNECSKTFRLRSYLASHRRVHSGEKPYKCN 529

Query: 703 ICHYPFTVKA--NCERHL-----------------RKKHLKATRK--DIEKNIEYVSSSA 741
            C   F+ ++  +C R L                  K  L   R+    EK+ +      
Sbjct: 530 ECSKTFSQRSYLHCHRRLHSGEKPYKCNECGKTFSHKPSLVHHRRLHTGEKSYKCTVCDK 589

Query: 742 AELVDAFCAPDT---------VCRLCGEDLKHYRALRIHMRTHCGRGL------------ 780
           A + +++ A  T          C  CG+       L +H R H G  L            
Sbjct: 590 AFVRNSYLARHTRIHTAEKPYKCNECGKAFNQQSQLSLHHRIHAGEKLYKCETCDKVFSR 649

Query: 781 -------GGGHKGRKPFECKECSAAFAAKRNCIHHILKQH--LHVPEQ 819
                     H G+KP++CK C   F +  +     LKQH  LH  E+
Sbjct: 650 KSHLKRHRRIHPGKKPYKCKVCDKTFGSDSH-----LKQHTGLHTGEK 692



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 31/192 (16%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K  + +  L  H R H   TG   + C++C K+    S L RH  +H+ E+PY
Sbjct: 554 YKCNECGKTFSHKPSLVHHRRLH---TGEKSYKCTVCDKAFVRNSYLARHTRIHTAEKPY 610

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC  CG++F     +  H +IH  +      T      ++  L   R++           
Sbjct: 611 KCNECGKAFNQQSQLSLHHRIHAGEKLYKCETCDKVFSRKSHLKRHRRIH---------- 660

Query: 186 APAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTF 244
            P KK                 + C VC K F     L+ H   H+ + P +C+ C   F
Sbjct: 661 -PGKK----------------PYKCKVCDKTFGSDSHLKQHTGLHTGEKPYKCNECGKAF 703

Query: 245 RTHRGLLRHNAL 256
                L+ H A+
Sbjct: 704 SKQSTLIHHQAV 715



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 51/189 (26%), Positives = 78/189 (41%), Gaps = 14/189 (7%)

Query: 633 KKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRT 692
           K+   MR+  + C    + F  S +LR H   HLG   Y+C++C  +   K  L  H R 
Sbjct: 152 KQEVYMREKSFQCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLTCHRRC 211

Query: 693 HSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPD 752
           H+GE+PY C  C   F+  ++   H R      + K  E    +  +SA  +  A    +
Sbjct: 212 HTGEKPYKCNECGKSFSQVSSLTCHRRLHTAVKSHKCNECGKIFGQNSALVIHKAIHTGE 271

Query: 753 T--VCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHIL 810
               C  C +       L  H R          H G KP++C+EC   F+ K     H  
Sbjct: 272 KPYKCNECDKAFNQQSNLARHRRI---------HTGEKPYKCEECDKVFSRKSTLESH-- 320

Query: 811 KQHLHVPEQ 819
            + +H  E+
Sbjct: 321 -KRIHTGEK 328



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 91/415 (21%), Positives = 148/415 (35%), Gaps = 41/415 (9%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C +VF   S+L+ H   HTG+KP+ C+ CD  F+  S   RH+    G  T      
Sbjct: 304  CEECDKVFSRKSTLESHKRIHTGEKPYKCKVCDTAFTWNSQLARHKRIHTGEKTYKCNEC 363

Query: 1308 GLIPQSKESDV------GSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVA 1361
            G     K S V      G   S   +   +  A    ++  T            E  +  
Sbjct: 364  GKTFSHKSSLVCHHRLHGGEKSYKCKVCDKAFAWNSHLVRHTRIHSGGKPYKCNECGKTF 423

Query: 1362 GDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFA 1421
            G          +   +H+  H   + ++ EE     E         E      + +  + 
Sbjct: 424  GQ--------NSDLLIHKSIHTGEQPYKYEEC----EKVFSCGSTLETHKIIHTGEKPYK 471

Query: 1422 TKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGD 1481
             K+ D   A     A      S E+   C+ C K+F+    L+ HR+ H  ++P      
Sbjct: 472  CKVCDKAFACHSYLAKHTRIHSGEKPYKCNECSKTFRLRSYLASHRRVHSGEKPYKCNEC 531

Query: 1482 GASTAE-------------EGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEG 1528
              + ++             E P    E  +     P+ V       GE   +    +   
Sbjct: 532  SKTFSQRSYLHCHRRLHSGEKPYKCNECGKTFSHKPSLVHHRRLHTGEKSYKCTVCDKAF 591

Query: 1529 PSDGESAAEKR--SSEK----SDDDKKPKTDSPKSVASKADKRKKV--CSVCNKRFWSLQ 1580
              +   A   R  ++EK    ++  K     S  S+  +    +K+  C  C+K F    
Sbjct: 592  VRNSYLARHTRIHTAEKPYKCNECGKAFNQQSQLSLHHRIHAGEKLYKCETCDKVFSRKS 651

Query: 1581 DLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHHGKDSDKE 1633
             L RH R H G++PYKC+ C++TF     L +H  +H  +K       GK   K+
Sbjct: 652  HLKRHRRIHPGKKPYKCKVCDKTFGSDSHLKQHTGLHTGEKPYKCNECGKAFSKQ 706



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 11/168 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H R H  +  ++CN C  I    +AL+ H   H+GE+PY C 
Sbjct: 218 YKCNECGKSFSQVSSLTCHRRLHTAVKSHKCNECGKIFGQNSALVIHKAIHTGEKPYKCN 277

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F  ++N  RH R    +   K  E +  +   S  E        +    C++C  
Sbjct: 278 ECDKAFNQQSNLARHRRIHTGEKPYKCEECDKVFSRKSTLESHKRIHTGEKPYKCKVCDT 337

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
                  L  H R          H G K ++C EC   F+ K + + H
Sbjct: 338 AFTWNSQLARHKRI---------HTGEKTYKCNECGKTFSHKSSLVCH 376



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 84/375 (22%), Positives = 130/375 (34%), Gaps = 51/375 (13%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C ++F     L  H   HTG+KP+ C +C   FS  S+            TC  R +
Sbjct: 192  CDVCGKLFNHKQYLTCHRRCHTGEKPYKCNECGKSFSQVSSL-----------TCHRRLH 240

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEV---LDLTSRDREQPSEGATELRQVAGDA 1364
              +   K ++ G     +S      A   GE     +   +   Q S  A   R   G+ 
Sbjct: 241  TAVKSHKCNECGKIFGQNSALVIHKAIHTGEKPYKCNECDKAFNQQSNLARHRRIHTGEK 300

Query: 1365 PVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKL 1424
            P +            EE  +  S +   E      TG+                 +  K+
Sbjct: 301  PYKC-----------EECDKVFSRKSTLESHKRIHTGEKP---------------YKCKV 334

Query: 1425 MDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGAS 1484
             D         A      + E+   C+ CGK+F    +L  H + HG ++    K    +
Sbjct: 335  CDTAFTWNSQLARHKRIHTGEKTYKCNECGKTFSHKSSLVCHHRLHGGEKSYKCKVCDKA 394

Query: 1485 TAEEGPQPAPEQEEK--PPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSE 1542
             A         +      P    E  ++     +    K     E P   E   +  S  
Sbjct: 395  FAWNSHLVRHTRIHSGGKPYKCNECGKTFGQNSDLLIHKSIHTGEQPYKYEECEKVFSCG 454

Query: 1543 KSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCER 1602
             + +  K        +    +K  K C VC+K F     L +H R H+GE+PYKC  C +
Sbjct: 455  STLETHK--------IIHTGEKPYK-CKVCDKAFACHSYLAKHTRIHSGEKPYKCNECSK 505

Query: 1603 TFTLKHSLVRHQRIH 1617
            TF L+  L  H+R+H
Sbjct: 506  TFRLRSYLASHRRVH 520



 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 3/82 (3%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C+K+ + +  L  H R H    G   + C +C K+  S S L +H  +H+GE+PY
Sbjct: 638 YKCETCDKVFSRKSHLKRHRRIH---PGKKPYKCKVCDKTFGSDSHLKQHTGLHTGEKPY 694

Query: 126 KCTVCGQSFTTNGNMHRHMKIH 147
           KC  CG++F+    +  H  +H
Sbjct: 695 KCNECGKAFSKQSTLIHHQAVH 716



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 3/93 (3%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           R+      +  Y C  C K    Q QL++H R H    G   + C  C K  S  S L R
Sbjct: 599 RHTRIHTAEKPYKCNECGKAFNQQSQLSLHHRIH---AGEKLYKCETCDKVFSRKSHLKR 655

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147
           H  +H G++PYKC VC ++F ++ ++ +H  +H
Sbjct: 656 HRRIHPGKKPYKCKVCDKTFGSDSHLKQHTGLH 688



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 38/108 (35%), Positives = 57/108 (52%), Gaps = 6/108 (5%)

Query: 1563 DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARH 1622
            DK+ K C VC K F   Q LT H R HTGE+PYKC  C ++F+   SL  H+R+H     
Sbjct: 187  DKQYK-CDVCGKLFNHKQYLTCHRRCHTGEKPYKCNECGKSFSQVSSLTCHRRLHTA--- 242

Query: 1623 AKHHGKDSDKEERGEEDS--ENESTHSGNNAVSENEAELAPNASNHMA 1668
             K H  +   +  G+  +   +++ H+G      NE + A N  +++A
Sbjct: 243  VKSHKCNECGKIFGQNSALVIHKAIHTGEKPYKCNECDKAFNQQSNLA 290



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 27/76 (35%), Positives = 40/76 (52%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           LY C  C++VF+    L+ H R H G  PY+C +CD      + L +H   H+GE+PY C
Sbjct: 637 LYKCETCDKVFSRKSHLKRHRRIHPGKKPYKCKVCDKTFGSDSHLKQHTGLHTGEKPYKC 696

Query: 702 KICHYPFTVKANCERH 717
             C   F+ ++    H
Sbjct: 697 NECGKAFSKQSTLIHH 712



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 49/177 (27%), Positives = 69/177 (38%), Gaps = 11/177 (6%)

Query: 1443 SQEQKLACDTCGKSFKFLGTLSRHRKAH-GRQEPKDEKGDGASTAEEGPQPAPEQEEKPP 1501
            S E+   C+ CGK+F    +L  HR+ H G +  K    D A         A        
Sbjct: 549  SGEKPYKCNECGKTFSHKPSLVHHRRLHTGEKSYKCTVCDKAFVRNS--YLARHTRIHTA 606

Query: 1502 ETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKR-SSEKSDDDKKPKTDSPKSVAS 1560
            E P +  E      +     L            A EK    E  D     K+   +    
Sbjct: 607  EKPYKCNECGKAFNQQSQLSLHHRIH-------AGEKLYKCETCDKVFSRKSHLKRHRRI 659

Query: 1561 KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
               K+   C VC+K F S   L +H   HTGE+PYKC  C + F+ + +L+ HQ +H
Sbjct: 660  HPGKKPYKCKVCDKTFGSDSHLKQHTGLHTGEKPYKCNECGKAFSKQSTLIHHQAVH 716



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 63/243 (25%), Positives = 94/243 (38%), Gaps = 38/243 (15%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHG--RQEPKDEKGD--GASTA---------EEGPQ 1491
            E+   C+ CGKSF  + +L+ HR+ H   +    +E G   G ++A          E P 
Sbjct: 215  EKPYKCNECGKSFSQVSSLTCHRRLHTAVKSHKCNECGKIFGQNSALVIHKAIHTGEKPY 274

Query: 1492 PAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAE--KRSSEKSDDDKK 1549
               E ++   +            GE P +   EE +     +S  E  KR        K 
Sbjct: 275  KCNECDKAFNQQSNLARHRRIHTGEKPYK--CEECDKVFSRKSTLESHKRIHTGEKPYKC 332

Query: 1550 PKTDSPKSVASKADKRKKV--------CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCE 1601
               D+  +  S+  + K++        C+ C K F     L  H R H GE+ YKC+ C+
Sbjct: 333  KVCDTAFTWNSQLARHKRIHTGEKTYKCNECGKTFSHKSSLVCHHRLHGGEKSYKCKVCD 392

Query: 1602 RTFTLKHSLVRHQRIHQKARHAKHHGKDSDKEERGEEDSEN------ESTHSGNNAVSEN 1655
            + F     LVRH RIH         GK     E G+   +N      +S H+G       
Sbjct: 393  KAFAWNSHLVRHTRIHS-------GGKPYKCNECGKTFGQNSDLLIHKSIHTGEQPYKYE 445

Query: 1656 EAE 1658
            E E
Sbjct: 446  ECE 448



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 1/52 (1%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGV 1299
            C  C + F   S L++H   HTG+KP+ C +C   FS +S    HQ   HGV
Sbjct: 668  CKVCDKTFGSDSHLKQHTGLHTGEKPYKCNECGKAFSKQSTLIHHQ-AVHGV 718



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 3/66 (4%)

Query: 54  RRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLD 113
           +R++     K  Y C +C+K   +   L  H   H   TG   + C+ CGK+ S  S+L 
Sbjct: 654 KRHRRIHPGKKPYKCKVCDKTFGSDSHLKQHTGLH---TGEKPYKCNECGKAFSKQSTLI 710

Query: 114 RHMLVH 119
            H  VH
Sbjct: 711 HHQAVH 716



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 17/51 (33%), Positives = 25/51 (49%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTH 693
           Y C+ C++ F     L+ H   H G  PY+CN C    + ++ LI H   H
Sbjct: 666 YKCKVCDKTFGSDSHLKQHTGLHTGEKPYKCNECGKAFSKQSTLIHHQAVH 716



 Score = 40.0 bits (92), Expect = 0.020
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 7/64 (10%)

Query: 1236 RNSYTNCLQKI-------TCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSN 1288
            + SY +C +++        C  C + F    SL  H   HTG+K + C  CD  F   S 
Sbjct: 537  QRSYLHCHRRLHSGEKPYKCNECGKTFSHKPSLVHHRRLHTGEKSYKCTVCDKAFVRNSY 596

Query: 1289 CERH 1292
              RH
Sbjct: 597  LARH 600



 Score = 38.5 bits (88), Expect = 0.058
 Identities = 17/49 (34%), Positives = 23/49 (46%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            C+   K F     L +H   H G++ YKC  C + F  K  L  H+R H
Sbjct: 164  CNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLTCHRRCH 212


>gi|38708324 zinc finger protein 93 [Homo sapiens]
          Length = 620

 Score =  103 bits (258), Expect = 1e-21
 Identities = 79/323 (24%), Positives = 131/323 (40%), Gaps = 16/323 (4%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C+K       L+ H   H   TG   + C  CGK+ + +S+L +H  +H+GE+PY
Sbjct: 229 YKCDKCDKAFIASSTLSKHEIIH---TGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPY 285

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC  CG++F  +  + +H KIH  +          +  K  R+ +  K  H  E   +  
Sbjct: 286 KCEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGKA-FKYSRILTTHKRIHTGEKPYKCN 344

Query: 186 APAKKMVEDGQSGDLE--KKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCV 242
              K  +        E      + + C  C K F+    L  H   H+ + P +C+ C  
Sbjct: 345 KCGKAFIASSTLSRHEFIHMGKKHYKCEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGK 404

Query: 243 TFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQ 299
            F+    L  H      + P   +  G+ F+ ++          G   + C +  +  +Q
Sbjct: 405 AFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFNQ 464

Query: 300 AWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALD 359
           +   T  ++  + +  + C+ C KAF    SL  HK+ H       EKP      G A +
Sbjct: 465 SSSLTKHKKIHTGEKPYKCEECGKAFNQSSSLTKHKKIHTG-----EKPYKCEECGKAFN 519

Query: 360 QKGFLALLGLQHTKDVRPAPAEE 382
           Q   L      HT++ +P   EE
Sbjct: 520 QSSTLIKHKKIHTRE-KPYKCEE 541



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 82/353 (23%), Positives = 135/353 (38%), Gaps = 21/353 (5%)

Query: 22  SAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQL 81
           S+ +S  ++   G  P   +   K    +    ++++    +  Y C  C K       L
Sbjct: 241 SSTLSKHEIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTL 300

Query: 82  TMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMH 141
           T H + H   TG   + C  CGK+   +  L  H  +H+GE+PYKC  CG++F  +  + 
Sbjct: 301 TKHKKIH---TGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLS 357

Query: 142 RHM-----KIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQ 196
           RH      K H K      A    S L R     KR  + +   + E+   A K      
Sbjct: 358 RHEFIHMGKKHYKCEECGKAFIWSSVLTRH----KRVHTGEKPYKCEECGKAFKYSSTLS 413

Query: 197 SGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNA 255
           S       ++ + C  C K FV    L  H   H+   P +C+ C   F     L +H  
Sbjct: 414 SHKRSHTGEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKK 473

Query: 256 LVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISE 312
           +   + P   +  G+ F Q++          G   + C +  +  +Q+      ++  + 
Sbjct: 474 IHTGEKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTR 533

Query: 313 QHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLA 365
           +  + C+ C KAF +   L  HK  H       EKP      G A +    L+
Sbjct: 534 EKPYKCEECGKAFHLSTHLTTHKILHTG-----EKPYRCRECGKAFNHSATLS 581



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 78/336 (23%), Positives = 133/336 (39%), Gaps = 21/336 (6%)

Query: 22  SAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQL 81
           S+ ++  K    G  P   +   K    +RI   ++     +  Y C  C K       L
Sbjct: 297 SSTLTKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTL 356

Query: 82  TMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMH 141
           + H   H    G   + C  CGK+   +S L RH  VH+GE+PYKC  CG++F  +  + 
Sbjct: 357 SRHEFIH---MGKKHYKCEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLS 413

Query: 142 RHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLE 201
            H + H  +          + +    LS K ++ H  +   +     K      QS  L 
Sbjct: 414 SHKRSHTGEKPYKCEECGKAFVASSTLS-KHEIIHTGKKPYKCEECGKAF---NQSSSLT 469

Query: 202 KK-----ADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNA 255
           K       ++ + C  C K F     L  H + H+ + P +C+ C   F     L++H  
Sbjct: 470 KHKKIHTGEKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKK 529

Query: 256 LVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISE 312
           +  ++ P   +  G+ F  +           G   + CR+  +  + +   ++ ++  S 
Sbjct: 530 IHTREKPYKCEECGKAFHLSTHLTTHKILHTGEKPYRCRECGKAFNHSATLSSHKKIHSG 589

Query: 313 QHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
           +  + CD C KAF    SL+ H+  H       EKP
Sbjct: 590 EKPYECDKCGKAFISPSSLSRHEIIHTG-----EKP 620



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 82/338 (24%), Positives = 130/338 (38%), Gaps = 44/338 (13%)

Query: 62  EKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSG 121
           EK  + C  C K       L  H + H   TG   + C  CGK+   +S+L+ H  +H+G
Sbjct: 169 EKKPFKCIECGKAFNQFSTLITHKKIH---TGEKPYICEECGKAFKYSSALNTHKRIHTG 225

Query: 122 ERPYKCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRKLSHDAES 180
           E+PYKC  C ++F  +  + +H  IH  K P             +    +K K  H  E 
Sbjct: 226 EKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCEECG--KAFNQSSTLTKHKKIHTGE- 282

Query: 181 EREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDI 239
                                    + + C  C K F     L  H + H+ + P  C+ 
Sbjct: 283 -------------------------KPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEE 317

Query: 240 CCVTFRTHRGLLRHNALVHKQLPR--DAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRI 297
           C   F+  R L  H  +   + P   +  G+ FI ++      F  +G   + C +  + 
Sbjct: 318 CGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKHYKCEECGK- 376

Query: 298 SQAWCE--TNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPG 355
           +  W    T  +R  + +  + C+ C KAF    +L+ HK++H       EKP      G
Sbjct: 377 AFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTG-----EKPYKCEECG 431

Query: 356 DALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQL 393
            A      L+   + HT   +P   EE     NQ+  L
Sbjct: 432 KAFVASSTLSKHEIIHT-GKKPYKCEECGKAFNQSSSL 468



 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 48/168 (28%), Positives = 69/168 (41%), Gaps = 11/168 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F +S  L  H R H G  PY+C+ CD      + L +H   H+G++PY C+
Sbjct: 201 YICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCE 260

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F   +   +H +    +   K  E    +  SS           +   VC  CG+
Sbjct: 261 ECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGK 320

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
             K+ R L  H R          H G KP++C +C  AF A      H
Sbjct: 321 AFKYSRILTTHKRI---------HTGEKPYKCNKCGKAFIASSTLSRH 359



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 51/175 (29%), Positives = 69/175 (39%), Gaps = 15/175 (8%)

Query: 638 MRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGER 697
           M K  Y C  C + F +S VL  H R H G  PY+C  C       + L  H R+H+GE+
Sbjct: 364 MGKKHYKCEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEK 423

Query: 698 PYICKICHYPFTVKANCER----HLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT 753
           PY C+ C   F   +   +    H  KK  K   ++  K     SS              
Sbjct: 424 PYKCEECGKAFVASSTLSKHEIIHTGKKPYKC--EECGKAFNQSSSLTKHKKIHTGEKPY 481

Query: 754 VCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
            C  CG+      +L  H +          H G KP++C+EC  AF      I H
Sbjct: 482 KCEECGKAFNQSSSLTKHKKI---------HTGEKPYKCEECGKAFNQSSTLIKH 527



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 46/170 (27%), Positives = 70/170 (41%), Gaps = 15/170 (8%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  L  H + H G  PY+C  C       ++L +H + H+GE+PY C+
Sbjct: 453 YKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCE 512

Query: 703 ICHYPF----TVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   F    T+  + + H R+K  K   ++  K     +      +         CR C
Sbjct: 513 ECGKAFNQSSTLIKHKKIHTREKPYKC--EECGKAFHLSTHLTTHKILHTGEKPYRCREC 570

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           G+   H   L  H + H          G KP+EC +C  AF +  +   H
Sbjct: 571 GKAFNHSATLSSHKKIH---------SGEKPYECDKCGKAFISPSSLSRH 611



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 53/182 (29%), Positives = 78/182 (42%), Gaps = 11/182 (6%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEP-KDEKGDGASTAEEG-PQPAPEQEEKPPE 1502
            E+   C+ CGK+FK+   L+ H++ H  ++P K +K D A  A     +       K P 
Sbjct: 198  EKPYICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPY 257

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKA 1562
               E  ++   +      K     E P   E    K  ++ S   K  K  +        
Sbjct: 258  KCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECG-KAFNQSSTLTKHKKIHT-------- 308

Query: 1563 DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARH 1622
             ++  VC  C K F   + LT H R HTGE+PYKC  C + F    +L RH+ IH   +H
Sbjct: 309  GEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKH 368

Query: 1623 AK 1624
             K
Sbjct: 369  YK 370



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 85/401 (21%), Positives = 142/401 (35%), Gaps = 47/401 (11%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F  +S+L +H + HTG+KP+ C++C   F+  S   +H+    G         
Sbjct: 231  CDKCDKAFIASSTLSKHEIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYKCEEC 290

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLD----LTSRDREQPSEGATELRQVAGD 1363
            G    ++ S +  H    +          G+       LT+  R    E   +  +  G 
Sbjct: 291  GKA-FNQSSTLTKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNK-CGK 348

Query: 1364 APVEQATAETASPVHR-------EEHGRG-----------ESHEPEEEHGTEESTGDADG 1405
            A +  +T      +H        EE G+              H  E+ +  EE      G
Sbjct: 349  AFIASSTLSRHEFIHMGKKHYKCEECGKAFIWSSVLTRHKRVHTGEKPYKCEEC-----G 403

Query: 1406 AEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKL-------ACDTCGKSFK 1458
                 SS  S      T    +K  E      A    S+ + +        C+ CGK+F 
Sbjct: 404  KAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFN 463

Query: 1459 FLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGE 1516
               +L++H+K H  ++P   +E G   + +    +       + P    E  ++   +  
Sbjct: 464  QSSSLTKHKKIHTGEKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSST 523

Query: 1517 APAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRF 1576
                K     E P   E   +           K        +    +K  + C  C K F
Sbjct: 524  LIKHKKIHTREKPYKCEECGKAFHLSTHLTTHK--------ILHTGEKPYR-CRECGKAF 574

Query: 1577 WSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                 L+ H + H+GE+PY+C  C + F    SL RH+ IH
Sbjct: 575  NHSATLSSHKKIHSGEKPYECDKCGKAFISPSSLSRHEIIH 615



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 37/181 (20%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEP-KDEKGDGASTAEEGPQPAPEQEEKPPET 1503
            E+   C+ CGK+FK+  TLS H+++H  ++P K E+   A  A                +
Sbjct: 394  EKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASS------------TLS 441

Query: 1504 PAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKAD 1563
              E++ +    G+ P +   EE     +  S+  K   +K    +KP             
Sbjct: 442  KHEIIHT----GKKPYK--CEECGKAFNQSSSLTKH--KKIHTGEKPYK----------- 482

Query: 1564 KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHA 1623
                 C  C K F     LT+H + HTGE+PYKC+ C + F    +L++H++IH + +  
Sbjct: 483  -----CEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTREKPY 537

Query: 1624 K 1624
            K
Sbjct: 538  K 538



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 20/227 (8%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPE--QEEKPPE 1502
            E+   C+ CGK+FK+   L+ H++ H  ++P      G +          E     K   
Sbjct: 310  EKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKHY 369

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAE--KRSSEKSDDDKKPKTDSPKSVAS 1560
               E  ++   +      K     E P   E   +  K SS  S   +    + P     
Sbjct: 370  KCEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYK--- 426

Query: 1561 KADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--Q 1618
                    C  C K F +   L++H   HTG++PYKC+ C + F    SL +H++IH  +
Sbjct: 427  --------CEECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIHTGE 478

Query: 1619 KARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASN 1665
            K    +  GK  +   +    ++++  H+G       E   A N S+
Sbjct: 479  KPYKCEECGKAFN---QSSSLTKHKKIHTGEKPYKCEECGKAFNQSS 522



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 58/229 (25%), Positives = 90/229 (39%), Gaps = 18/229 (7%)

Query: 1450 CDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQPAPEQEEKPPETPAEV 1507
            C+ CGK+F    TL++H+K H  ++P   +E G   + +    +       + P    E 
Sbjct: 259  CEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEEC 318

Query: 1508 VESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKK 1567
             ++   +      K     E P       +   +          T S         K  K
Sbjct: 319  GKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASS--------TLSRHEFIHMGKKHYK 370

Query: 1568 VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKH 1625
             C  C K F     LTRH R HTGE+PYKC+ C + F    +L  H+R H  +K    + 
Sbjct: 371  -CEECGKAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEE 429

Query: 1626 HGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRK 1674
             GK           S++E  H+G       E   A N S+  ++T+ +K
Sbjct: 430  CGK---AFVASSTLSKHEIIHTGKKPYKCEECGKAFNQSS--SLTKHKK 473



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 53/202 (26%), Positives = 80/202 (39%), Gaps = 30/202 (14%)

Query: 642 LYPCRFCNQVF-AFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYI 700
           ++ C    +VF  FS   R ++R H    P++C  C       + LI H + H+GE+PYI
Sbjct: 144 VFQCDKYGKVFHKFSNSNRHNIR-HTEKKPFKCIECGKAFNQFSTLITHKKIHTGEKPYI 202

Query: 701 CKICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
           C+ C   F   +    H R    +K  K  + D +  I   + S  E++     P   C 
Sbjct: 203 CEECGKAFKYSSALNTHKRIHTGEKPYKCDKCD-KAFIASSTLSKHEIIHTGKKP-YKCE 260

Query: 757 LCGEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSA 797
            CG+       L  H + H          CG+              H G KP+ C+EC  
Sbjct: 261 ECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGK 320

Query: 798 AFAAKRNCIHHILKQHLHVPEQ 819
           AF   R    H   + +H  E+
Sbjct: 321 AFKYSRILTTH---KRIHTGEK 339



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 28/79 (35%), Positives = 35/79 (44%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           R+  Y C  C + F  S  L  H   H G  PY+C  C       A L  H + HSGE+P
Sbjct: 533 REKPYKCEECGKAFHLSTHLTTHKILHTGEKPYRCRECGKAFNHSATLSSHKKIHSGEKP 592

Query: 699 YICKICHYPFTVKANCERH 717
           Y C  C   F   ++  RH
Sbjct: 593 YECDKCGKAFISPSSLSRH 611



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)

Query: 1568 VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKH 1625
            +C  C K F     L  H R HTGE+PYKC  C++ F    +L +H+ IH  +K    + 
Sbjct: 202  ICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCEE 261

Query: 1626 HGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRK 1674
             GK  +   +    ++++  H+G       E   A N S+   +T+ +K
Sbjct: 262  CGKAFN---QSSTLTKHKKIHTGEKPYKCEECGKAFNQSS--TLTKHKK 305



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 52/240 (21%), Positives = 91/240 (37%), Gaps = 30/240 (12%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQL-----RKHGVTTC 1302
            C  C + F ++S+L  H  +HTG+KP+ C++C   F   S   +H++     + +    C
Sbjct: 399  CEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKCEEC 458

Query: 1303 SLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAG 1362
                N     +K   +  H         E   A  +   LT   +    E   +  +  G
Sbjct: 459  GKAFNQSSSLTKHKKI--HTGEKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEE-CG 515

Query: 1363 DAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFAT 1422
             A  + +T       H++ H R + ++ EE        G A       ++++ L     T
Sbjct: 516  KAFNQSSTLIK----HKKIHTREKPYKCEE-------CGKAFHLSTHLTTHKILH----T 560

Query: 1423 KLMDFKLAEGDGEAGAGGAASQEQKL-------ACDTCGKSFKFLGTLSRHRKAHGRQEP 1475
                ++  E           S  +K+        CD CGK+F    +LSRH   H  ++P
Sbjct: 561  GEKPYRCRECGKAFNHSATLSSHKKIHSGEKPYECDKCGKAFISPSSLSRHEIIHTGEKP 620



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 11/116 (9%)

Query: 1563 DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARH 1622
            +K+   C  C K F     L  H + HTGE+PY C+ C + F    +L  H+RIH   + 
Sbjct: 169  EKKPFKCIECGKAFNQFSTLITHKKIHTGEKPYICEECGKAFKYSSALNTHKRIHTGEKP 228

Query: 1623 AKHHGKDSDKEER----GEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRK 1674
             K      DK ++        S++E  H+G       E   A N S+   +T+ +K
Sbjct: 229  YK-----CDKCDKAFIASSTLSKHEIIHTGKKPYKCEECGKAFNQSS--TLTKHKK 277



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 18/47 (38%), Positives = 27/47 (57%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQL 1294
            C  C + F ++S+L  H   HTG+KP+ C KCD  F   S   +H++
Sbjct: 203  CEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEI 249



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 21/56 (37%), Positives = 30/56 (53%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           Y CR C + F  S  L +H + H G  PY+C+ C       ++L RH   H+GE+P
Sbjct: 565 YRCRECGKAFNHSATLSSHKKIHSGEKPYECDKCGKAFISPSSLSRHEIIHTGEKP 620



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            C    K F    +  RH   HT ++P+KC  C + F    +L+ H++IH
Sbjct: 147  CDKYGKVFHKFSNSNRHNIRHTEKKPFKCIECGKAFNQFSTLITHKKIH 195



 Score = 38.1 bits (87), Expect = 0.075
 Identities = 16/46 (34%), Positives = 23/46 (50%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S+L  H   HTG+KP+ C++C   F   S    H+
Sbjct: 175  CIECGKAFNQFSTLITHKKIHTGEKPYICEECGKAFKYSSALNTHK 220



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 16/46 (34%), Positives = 23/46 (50%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C    +VF   S+  RH + HT +KPF C +C   F+  S    H+
Sbjct: 147  CDKYGKVFHKFSNSNRHNIRHTEKKPFKCIECGKAFNQFSTLITHK 192


>gi|153791560 zinc finger protein 799 [Homo sapiens]
          Length = 643

 Score =  103 bits (258), Expect = 1e-21
 Identities = 90/324 (27%), Positives = 134/324 (41%), Gaps = 31/324 (9%)

Query: 31  TENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNT 90
           T  G  P   K  SK         R++ T   +  Y C  C K          H R H  
Sbjct: 218 THTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKLYECKQCSKAFPDYSSCLRHERTH-- 275

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
            TG   ++C  CGK+ S+++SL RH   H+ E+PY C  CG++F   G+  RHM +H +D
Sbjct: 276 -TGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPYACQQCGKAFHHLGSFQRHMVMHTRD 334

Query: 151 -PNSATATAP----PSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKAD 205
            P+           PS LK    S +R  + +   E +    A       +        D
Sbjct: 335 GPHKCKICGKGFDCPSSLK----SHERTHTGEKLYECKQCGKALSHSSSFRRHMTMHTGD 390

Query: 206 EVFHCPVCFKEFVCKYGLETHMETH-SDNPLRCDICCVTFRTHRGLLRHNALVHKQLP-R 263
               C +C K FV     + H +TH ++ P +C  C   +R    L RH      + P +
Sbjct: 391 GPHKCKICGKAFVYPSVFQRHEKTHTAEKPYKCKQCGKAYRISSSLRRHETTHTGEKPYK 450

Query: 264 DAMGRPFI-----QNNPSIPAGFHDLGFTD----FSCRKFPRISQAWCETNLRRCISEQH 314
              G+ FI     QN+ +  AG       +    FSC  F  +SQ       RR  + + 
Sbjct: 451 CKCGKAFIDFYSFQNHKTTHAGEKPYECKECGKAFSC--FQYLSQH------RRTHTGEK 502

Query: 315 RFVCDTCDKAFPMLCSLALHKQTH 338
            + C+TC KAF    +L +H++ H
Sbjct: 503 PYECNTCKKAFSHFGNLKVHERIH 526



 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 93/375 (24%), Positives = 140/375 (37%), Gaps = 72/375 (19%)

Query: 31  TENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEK----ICTTQHQLTMHIR 86
           T  G  P   K   K    +   RR++ T  ++  Y C  C K    + + Q  + MH R
Sbjct: 274 THTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPYACQQCGKAFHHLGSFQRHMVMHTR 333

Query: 87  Q---------------------HNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
                                   T TG   + C  CGK+LS +SS  RHM +H+G+ P+
Sbjct: 334 DGPHKCKICGKGFDCPSSLKSHERTHTGEKLYECKQCGKALSHSSSFRRHMTMHTGDGPH 393

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           KC +CG++F       RH K H  +             K  R+SS  +  H+     E P
Sbjct: 394 KCKICGKAFVYPSVFQRHEKTHTAEKPYKCKQCG----KAYRISSSLR-RHETTHTGEKP 448

Query: 186 APAK--KMVEDGQSGDLEKKA---DEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDI 239
              K  K   D  S    K     ++ + C  C K F C   L  H  TH+ + P  C+ 
Sbjct: 449 YKCKCGKAFIDFYSFQNHKTTHAGEKPYECKECGKAFSCFQYLSQHRRTHTGEKPYECNT 508

Query: 240 CCVTF----------RTHRG------------------LLRHNALVHKQLPRDAM--GRP 269
           C   F          R H G                   LRH  +  ++ P +    G+ 
Sbjct: 509 CKKAFSHFGNLKVHERIHSGEKPYECKECGKAFSWLTCFLRHERIHMREKPYECQQCGKA 568

Query: 270 FIQNNPSIPAGFHDLGFTDFSCRK----FPRISQAWC--ETNLRRCISEQHRFVCDTCDK 323
           F  +           G   + C++    F  +S      +T+ ++  + ++ + C  C K
Sbjct: 569 FTHSRFLQGHEKTHTGENPYECKECGKAFASLSSLHRHKKTHWKKTHTGENPYGCKECGK 628

Query: 324 AFPMLCSLALHKQTH 338
           AF  L SL  HK+TH
Sbjct: 629 AFASLSSLHRHKKTH 643



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 93/419 (22%), Positives = 157/419 (37%), Gaps = 55/419 (13%)

Query: 1229 DKLLRAKRNS-----YTNCLQK---------ITCPHCPRVFPWASSLQRHMLTHTGQKPF 1274
            +KL   K+ S     Y++CL+           TC  C + F  ++SL+RH  THT +KP+
Sbjct: 250  EKLYECKQCSKAFPDYSSCLRHERTHTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPY 309

Query: 1275 PCQKCDAFFSTKSNCERHQL--RKHGVTTCSLRRNGLIPQSKESDVGSHDSTDSQSDAET 1332
             CQ+C   F    + +RH +   + G   C +   G       S + SH+ T +      
Sbjct: 310  ACQQCGKAFHHLGSFQRHMVMHTRDGPHKCKICGKGF---DCPSSLKSHERTHTGEKLYE 366

Query: 1333 AAAAGEVLDLTSRDRE----QPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESH 1388
                G+ L  +S  R        +G  + + + G A V  +  +     H + H   + +
Sbjct: 367  CKQCGKALSHSSSFRRHMTMHTGDGPHKCK-ICGKAFVYPSVFQR----HEKTHTAEKPY 421

Query: 1389 EPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKL 1448
            + ++       +      E   +  +          +DF   +      AG     E+  
Sbjct: 422  KCKQCGKAYRISSSLRRHETTHTGEKPYKCKCGKAFIDFYSFQNHKTTHAG-----EKPY 476

Query: 1449 ACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVV 1508
             C  CGK+F     LS+HR+ H  ++P +      + +  G     E+     E P E  
Sbjct: 477  ECKECGKAFSCFQYLSQHRRTHTGEKPYECNTCKKAFSHFGNLKVHERIHS-GEKPYECK 535

Query: 1509 ESAPGAGEAPA---EKLAEETEGPSDGESAAEKRSSEK--SDDDKKPKTDSPKSVASKAD 1563
            E              +     E P + +   +  +  +     +K    ++P        
Sbjct: 536  ECGKAFSWLTCFLRHERIHMREKPYECQQCGKAFTHSRFLQGHEKTHTGENPYE------ 589

Query: 1564 KRKKVCSVCNKRFWSLQDLTRH-----MRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                 C  C K F SL  L RH      ++HTGE PY C+ C + F    SL RH++ H
Sbjct: 590  -----CKECGKAFASLSSLHRHKKTHWKKTHTGENPYGCKECGKAFASLSSLHRHKKTH 643



 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 53/188 (28%), Positives = 78/188 (41%), Gaps = 21/188 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C + F +  +L  H R+H G  PY+C  C    +  ++ +RH RTH+GE+ Y CK
Sbjct: 197 YKCKLCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKLYECK 256

Query: 703 ICHYPFTVKANCERHLRKKHLKA--TRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   F   ++C RH R    K   T K   K     +S               C+ CG+
Sbjct: 257 QCSKAFPDYSSCLRHERTHTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPYACQQCGK 316

Query: 761 DLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAAFAA 801
              H  + + HM  H          CG+G             H G K +ECK+C  A + 
Sbjct: 317 AFHHLGSFQRHMVMHTRDGPHKCKICGKGFDCPSSLKSHERTHTGEKLYECKQCGKALSH 376

Query: 802 KRNCIHHI 809
             +   H+
Sbjct: 377 SSSFRRHM 384



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 56/171 (32%), Positives = 74/171 (43%), Gaps = 36/171 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C + F+    L  H R+H G  PY+CN C    +    L  H R HSGE+PY CK
Sbjct: 476 YECKECGKAFSCFQYLSQHRRTHTGEKPYECNTCKKAFSHFGNLKVHERIHSGEKPYECK 535

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+      RH R  H++      EK  E                   C+ CG+  
Sbjct: 536 ECGKAFSWLTCFLRHERI-HMR------EKPYE-------------------CQQCGKAF 569

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQH 813
            H R L+ H +TH G           P+ECKEC  AFA+  + +H   K H
Sbjct: 570 THSRFLQGHEKTHTGEN---------PYECKECGKAFAS-LSSLHRHKKTH 610



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 29/204 (14%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           LY C+ C +  + S   R H+  H G  P++C IC       +   RH +TH+ E+PY C
Sbjct: 364 LYECKQCGKALSHSSSFRRHMTMHTGDGPHKCKICGKAFVYPSVFQRHEKTHTAEKPYKC 423

Query: 702 KICHYPFTVKANCER----HLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRL 757
           K C   + + ++  R    H  +K  K   K  +  I++ S    +   A   P   C+ 
Sbjct: 424 KQCGKAYRISSSLRRHETTHTGEKPYKC--KCGKAFIDFYSFQNHKTTHAGEKP-YECKE 480

Query: 758 CGEDLKHYRALRIHMRTHCGR-------------GLGG------GHKGRKPFECKECSAA 798
           CG+    ++ L  H RTH G                G        H G KP+ECKEC  A
Sbjct: 481 CGKAFSCFQYLSQHRRTHTGEKPYECNTCKKAFSHFGNLKVHERIHSGEKPYECKECGKA 540

Query: 799 FAAKRNCIHHILKQHLHVPEQDIE 822
           F+     + H   + +H+ E+  E
Sbjct: 541 FSWLTCFLRH---ERIHMREKPYE 561



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 88/384 (22%), Positives = 138/384 (35%), Gaps = 46/384 (11%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F W S L  H  THTG+KP+ C++C   FS  S+  RH+    G      ++ 
Sbjct: 199  CKLCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKLYECKQC 258

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
                    S +  H+ T +     T    G+               +T LR+        
Sbjct: 259  SKAFPDYSSCL-RHERTHTGKKPYTCKQCGKAFS-----------ASTSLRR-------H 299

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
            + T     P   ++ G+   H    +      T   DG  +     +  D   + K  + 
Sbjct: 300  ETTHTDEKPYACQQCGKAFHHLGSFQRHMVMHT--RDGPHKCKICGKGFDCPSSLKSHE- 356

Query: 1428 KLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAE 1487
                           + E+   C  CGK+     +  RH   H    P   K  G +   
Sbjct: 357  ------------RTHTGEKLYECKQCGKALSHSSSFRRHMTMHTGDGPHKCKICGKAFV- 403

Query: 1488 EGPQPAPEQEEKPPETPAEVVESAPGAGEA-PAEKLAEETEGPSDGESAAEKRSSEKSDD 1546
                P+  Q  +   T AE        G+A          E    GE   + +  +   D
Sbjct: 404  ---YPSVFQRHEKTHT-AEKPYKCKQCGKAYRISSSLRRHETTHTGEKPYKCKCGKAFID 459

Query: 1547 DKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTL 1606
                +        + A ++   C  C K F   Q L++H R+HTGE+PY+C TC++ F+ 
Sbjct: 460  FYSFQNHK----TTHAGEKPYECKECGKAFSCFQYLSQHRRTHTGEKPYECNTCKKAFSH 515

Query: 1607 KHSLVRHQRIH--QKARHAKHHGK 1628
              +L  H+RIH  +K    K  GK
Sbjct: 516  FGNLKVHERIHSGEKPYECKECGK 539



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 84/371 (22%), Positives = 129/371 (34%), Gaps = 81/371 (21%)

Query: 1253 RVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQL--RKHGVTTCSLRRNGLI 1310
            + F + +SLQ H   HTG+KP+ C++C   FS+  N +RH    R  G   C L      
Sbjct: 148  KAFSYHNSLQTHERLHTGKKPYNCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFF 207

Query: 1311 -PQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQA 1369
             P        +H         + + A          +R    E   E +Q +      +A
Sbjct: 208  WPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKLYECKQCS------KA 261

Query: 1370 TAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKL 1429
              + +S +  E    G      ++  T +  G A  A      +++   D          
Sbjct: 262  FPDYSSCLRHERTHTG------KKPYTCKQCGKAFSASTSLRRHETTHTD---------- 305

Query: 1430 AEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEK--GDGASTAE 1487
                           E+  AC  CGK+F  LG+  RH   H R  P   K  G G     
Sbjct: 306  ---------------EKPYACQQCGKAFHHLGSFQRHMVMHTRDGPHKCKICGKGFDC-- 348

Query: 1488 EGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETE-GPSDGESAAEKRSSEKSDD 1546
                P+  +  +   T                EKL E  + G +   S++ +R       
Sbjct: 349  ----PSSLKSHERTHT---------------GEKLYECKQCGKALSHSSSFRRHMTMHTG 389

Query: 1547 DKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTL 1606
            D   K                 C +C K F       RH ++HT E+PYKC+ C + + +
Sbjct: 390  DGPHK-----------------CKICGKAFVYPSVFQRHEKTHTAEKPYKCKQCGKAYRI 432

Query: 1607 KHSLVRHQRIH 1617
              SL RH+  H
Sbjct: 433  SSSLRRHETTH 443



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 93/405 (22%), Positives = 151/405 (37%), Gaps = 46/405 (11%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F + SS  RH  THTG+K + C++C   F   S+C RH+    G    + ++ 
Sbjct: 227  CKQCSKAFSFYSSYLRHERTHTGEKLYECKQCSKAFPDYSSCLRHERTHTGKKPYTCKQC 286

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEV---LDLTSRDREQPSEGATELRQVAG-- 1362
            G    S  + +  H++T +          G+    L    R     +       ++ G  
Sbjct: 287  GKA-FSASTSLRRHETTHTDEKPYACQQCGKAFHHLGSFQRHMVMHTRDGPHKCKICGKG 345

Query: 1363 -DAPVEQATAETASPVHR----EEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLD 1417
             D P    + E      +    ++ G+  SH           TGD  G  +     ++  
Sbjct: 346  FDCPSSLKSHERTHTGEKLYECKQCGKALSHSSSFRRHMTMHTGD--GPHKCKICGKAFV 403

Query: 1418 LDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKD 1477
                     F+  E    A        E+   C  CGK+++   +L RH   H  ++P  
Sbjct: 404  YPSV-----FQRHEKTHTA--------EKPYKCKQCGKAYRISSSLRRHETTHTGEKPYK 450

Query: 1478 EKGDGA----------STAEEGPQPAPEQEEKPPETPAEVVES--APGAGEAPAEKLAEE 1525
             K   A           T   G +P   +E     +  + +        GE P E    +
Sbjct: 451  CKCGKAFIDFYSFQNHKTTHAGEKPYECKECGKAFSCFQYLSQHRRTHTGEKPYECNTCK 510

Query: 1526 TEGPSDGESAAEKR--SSEKSDDDKK-PKTDSPKSVASKADK---RKKV--CSVCNKRFW 1577
                  G     +R  S EK  + K+  K  S  +   + ++   R+K   C  C K F 
Sbjct: 511  KAFSHFGNLKVHERIHSGEKPYECKECGKAFSWLTCFLRHERIHMREKPYECQQCGKAFT 570

Query: 1578 SLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARH 1622
              + L  H ++HTGE PY+C+ C + F    SL RH++ H K  H
Sbjct: 571  HSRFLQGHEKTHTGENPYECKECGKAFASLSSLHRHKKTHWKKTH 615



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 75/289 (25%), Positives = 109/289 (37%), Gaps = 29/289 (10%)

Query: 73  KICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQ 132
           K  +  + L  H R H   TG   ++C  CGKS SS  +L RHM V  G+ PYKC +CG+
Sbjct: 148 KAFSYHNSLQTHERLH---TGKKPYNCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGK 204

Query: 133 SFTTNGNMHRHMKIH------EKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPA 186
           +F     +H H + H      E    S   +   S L+  R  +  KL    +  +  P 
Sbjct: 205 AFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKLYECKQCSKAFPD 264

Query: 187 PAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSD-NPLRCDICCVTFR 245
            +  +       +      + + C  C K F     L  H  TH+D  P  C  C   F 
Sbjct: 265 YSSCL-----RHERTHTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPYACQQCGKAFH 319

Query: 246 THRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCE 303
                 RH  +  +  P      G+ F  + PS     H+   T     +  +  +A   
Sbjct: 320 HLGSFQRHMVMHTRDGPHKCKICGKGF--DCPS-SLKSHERTHTGEKLYECKQCGKALSH 376

Query: 304 TNLRRCISEQHR----FVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
           ++  R     H       C  C KAF        H++TH A     EKP
Sbjct: 377 SSSFRRHMTMHTGDGPHKCKICGKAFVYPSVFQRHEKTHTA-----EKP 420



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 35/166 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C + F+  G L+ H+    G  PY+C +C       + L  H RTH+GE+PY CK
Sbjct: 169 YNCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTHTGEKPYECK 228

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+  ++  RH R                  + +  +L +        C+ C +  
Sbjct: 229 QCSKAFSFYSSYLRHER------------------THTGEKLYE--------CKQCSKAF 262

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
             Y +   H RT         H G+KP+ CK+C  AF+A  +   H
Sbjct: 263 PDYSSCLRHERT---------HTGKKPYTCKQCGKAFSASTSLRRH 299



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 48/171 (28%), Positives = 67/171 (39%), Gaps = 31/171 (18%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+  G L+ H R H G  PY+C  C    +     +RH R H  E+PY C+
Sbjct: 504 YECNTCKKAFSHFGNLKVHERIHSGEKPYECKECGKAFSWLTCFLRHERIHMREKPYECQ 563

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   FT     + H  K H      +                         C+ CG+  
Sbjct: 564 QCGKAFTHSRFLQGH-EKTHTGENPYE-------------------------CKECGKAF 597

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQH 813
               +L  H +TH  +     H G  P+ CKEC  AFA+  + +H   K H
Sbjct: 598 ASLSSLHRHKKTHWKK----THTGENPYGCKECGKAFAS-LSSLHRHKKTH 643



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 47/181 (25%), Positives = 76/181 (41%), Gaps = 13/181 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C+ C + F     L++H R+H G   Y+C  C    +  ++  RH+  H+G+ P+ CK
Sbjct: 337 HKCKICGKGFDCPSSLKSHERTHTGEKLYECKQCGKALSHSSSFRRHMTMHTGDGPHKCK 396

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEY-VSSSAAELVDAFCAPDTVCRLCGED 761
           IC   F   +  +RH +    +   K  +    Y +SSS                 CG+ 
Sbjct: 397 ICGKAFVYPSVFQRHEKTHTAEKPYKCKQCGKAYRISSSLRRHETTHTGEKPYKCKCGKA 456

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDI 821
              + + + H  TH          G KP+ECKEC  AF+  +    H   +  H  E+  
Sbjct: 457 FIDFYSFQNHKTTHA---------GEKPYECKECGKAFSCFQYLSQH---RRTHTGEKPY 504

Query: 822 E 822
           E
Sbjct: 505 E 505



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 53/189 (28%), Positives = 78/189 (41%), Gaps = 23/189 (12%)

Query: 642 LYPCRFCNQVFA-FSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYI 700
           LY C+ C++ F  +S  LR H R+H G  PY C  C    +   +L RH  TH+ E+PY 
Sbjct: 252 LYECKQCSKAFPDYSSCLR-HERTHTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPYA 310

Query: 701 CKICHYPFTVKANCERH--LRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
           C+ C   F    + +RH  +  +      K   K  +  SS  +            C+ C
Sbjct: 311 CQQCGKAFHHLGSFQRHMVMHTRDGPHKCKICGKGFDCPSSLKSHERTHTGEKLYECKQC 370

Query: 759 GEDLKHYRALRIHMRTHCGRG-----LGG--------------GHKGRKPFECKECSAAF 799
           G+ L H  + R HM  H G G     + G               H   KP++CK+C  A+
Sbjct: 371 GKALSHSSSFRRHMTMHTGDGPHKCKICGKAFVYPSVFQRHEKTHTAEKPYKCKQCGKAY 430

Query: 800 AAKRNCIHH 808
               +   H
Sbjct: 431 RISSSLRRH 439



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 6/90 (6%)

Query: 638 MRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRH-----LRT 692
           MR+  Y C+ C + F  S  L+ H ++H G +PY+C  C    A  ++L RH      +T
Sbjct: 555 MREKPYECQQCGKAFTHSRFLQGHEKTHTGENPYECKECGKAFASLSSLHRHKKTHWKKT 614

Query: 693 HSGERPYICKICHYPFTVKANCERHLRKKH 722
           H+GE PY CK C   F   ++  RH +K H
Sbjct: 615 HTGENPYGCKECGKAFASLSSLHRH-KKTH 643



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 55/238 (23%), Positives = 81/238 (34%), Gaps = 27/238 (11%)

Query: 103 GKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD-PNSATATAPPS 161
           GK+ S  +SL  H  +H+G++PY C  CG+SF++ GN+ RHM +   D P          
Sbjct: 147 GKAFSYHNSLQTHERLHTGKKPYNCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAF 206

Query: 162 PLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKY 221
                    +R  + +   E +  + A          +     ++++ C  C K F    
Sbjct: 207 FWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKLYECKQCSKAFPDYS 266

Query: 222 GLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAG 280
               H  TH+   P  C  C   F     L RH      + P                  
Sbjct: 267 SCLRHERTHTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPYACQ---------QCGKA 317

Query: 281 FHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
           FH LG        F R           +         C  C K F    SL  H++TH
Sbjct: 318 FHHLG-------SFQRHMVMHTRDGPHK---------CKICGKGFDCPSSLKSHERTH 359



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 79/345 (22%), Positives = 118/345 (34%), Gaps = 68/345 (19%)

Query: 38  QGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADH 97
           Q I+   + P  N   R  +   E K    C        T  Q+   I   NT  G   +
Sbjct: 50  QNIEDQYRYPRKNLRCRMLERFVESKDGTQCG------ETSSQIQDSIVTKNTLPGVGPY 103

Query: 98  SCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATAT 157
              + G+ +   SSL+ ++ V +G +PY+   CG+   T+    +    H          
Sbjct: 104 ESRMSGEVIMGHSSLNCYIRVGAGHKPYEYHECGEKPDTHKQRGKAFSYHN--------- 154

Query: 158 APPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQS-GDLEK-----KADEVFHCP 211
              S     RL + +K           P   K+  +   S G+L++     + D  + C 
Sbjct: 155 ---SLQTHERLHTGKK-----------PYNCKECGKSFSSLGNLQRHMAVQRGDGPYKCK 200

Query: 212 VCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPF 270
           +C K F     L  H  TH+ + P  C  C   F  +   LRH         R   G   
Sbjct: 201 LCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHE--------RTHTGEKL 252

Query: 271 IQNNPSIPAGFHDLGFTDF-SCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLC 329
            +      A      F D+ SC +  R              + +  + C  C KAF    
Sbjct: 253 YECKQCSKA------FPDYSSCLRHERTH------------TGKKPYTCKQCGKAFSAST 294

Query: 330 SLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKD 374
           SL  H+ TH       EKP A    G A    G      + HT+D
Sbjct: 295 SLRRHETTHT-----DEKPYACQQCGKAFHHLGSFQRHMVMHTRD 334



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 54/200 (27%), Positives = 73/200 (36%), Gaps = 10/200 (5%)

Query: 1450 CDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVE 1509
            C  CGKSF  LG L RH        P   K  G +          E+     E P E  +
Sbjct: 171  CKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTHTG-EKPYECKQ 229

Query: 1510 SAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVC 1569
             +       +    E T     GE   E +   K+  D    +   +   +   K+   C
Sbjct: 230  CSKAFSFYSSYLRHERTH---TGEKLYECKQCSKAFPDY---SSCLRHERTHTGKKPYTC 283

Query: 1570 SVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKD 1629
              C K F +   L RH  +HT E+PY CQ C + F    S  RH  +H   R   H  K 
Sbjct: 284  KQCGKAFSASTSLRRHETTHTDEKPYACQQCGKAFHHLGSFQRHMVMH--TRDGPHKCKI 341

Query: 1630 SDKE-ERGEEDSENESTHSG 1648
              K  +       +E TH+G
Sbjct: 342  CGKGFDCPSSLKSHERTHTG 361



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 45/212 (21%), Positives = 75/212 (35%), Gaps = 24/212 (11%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEK--GDGASTAEEGPQPAPEQEEKPPE 1502
            E+   C  C K+F    +  RH + H  ++P   K  G   S +    +      ++ P 
Sbjct: 250  EKLYECKQCSKAFPDYSSCLRHERTHTGKKPYTCKQCGKAFSASTSLRRHETTHTDEKPY 309

Query: 1503 TPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASK- 1561
               +  ++    G      +    +GP   +   +               D P S+ S  
Sbjct: 310  ACQQCGKAFHHLGSFQRHMVMHTRDGPHKCKICGKG-------------FDCPSSLKSHE 356

Query: 1562 ---ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH- 1617
                 ++   C  C K         RHM  HTG+ P+KC+ C + F       RH++ H 
Sbjct: 357  RTHTGEKLYECKQCGKALSHSSSFRRHMTMHTGDGPHKCKICGKAFVYPSVFQRHEKTHT 416

Query: 1618 -QKARHAKHHGKDSDKEERGEEDSENESTHSG 1648
             +K    K  GK             +E+TH+G
Sbjct: 417  AEKPYKCKQCGK---AYRISSSLRRHETTHTG 445



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/156 (22%), Positives = 62/156 (39%), Gaps = 25/156 (16%)

Query: 667 GISPYQCNICDYIAADKAALIRHLRTHSGERPYICKIC--------------HYPFTVKA 712
           G+ PY+  +   +    ++L  ++R  +G +PY    C               Y  +++ 
Sbjct: 99  GVGPYESRMSGEVIMGHSSLNCYIRVGAGHKPYEYHECGEKPDTHKQRGKAFSYHNSLQT 158

Query: 713 NCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHM 772
           +   H  KK      K+  K+   + +    +          C+LCG+       L +H 
Sbjct: 159 HERLHTGKKPYNC--KECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHE 216

Query: 773 RTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
           RT         H G KP+ECK+CS AF+   + + H
Sbjct: 217 RT---------HTGEKPYECKQCSKAFSFYSSYLRH 243



 Score = 38.5 bits (88), Expect = 0.058
 Identities = 16/45 (35%), Positives = 25/45 (55%)

Query: 1574 KRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQ 1618
            K F     L  H R HTG++PY C+ C ++F+   +L RH  + +
Sbjct: 148  KAFSYHNSLQTHERLHTGKKPYNCKECGKSFSSLGNLQRHMAVQR 192



 Score = 35.0 bits (79), Expect = 0.64
 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 9/54 (16%)

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQ 812
           G+   ++ +L+ H R H G+         KP+ CKEC  +F++  N   H+  Q
Sbjct: 147 GKAFSYHNSLQTHERLHTGK---------KPYNCKECGKSFSSLGNLQRHMAVQ 191


>gi|23308729 zinc finger protein 268 [Homo sapiens]
          Length = 947

 Score =  103 bits (257), Expect = 1e-21
 Identities = 79/284 (27%), Positives = 123/284 (43%), Gaps = 18/284 (6%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K  + + QL +H R H   TG   + CS CGK+  S S L  HM  H+GE+P+
Sbjct: 668 YGCSQCAKTFSLKSQLIVHQRSH---TGVKPYGCSECGKAFRSKSYLIIHMRTHTGEKPH 724

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           +C  CG+SF+ N  +  H +IH  + N    +       R+     + +SH      E P
Sbjct: 725 ECRECGKSFSFNSQLIVHQRIHTGE-NPYECSECGKAFNRK----DQLISHQRTHAGEKP 779

Query: 186 APAKKMVEDGQSGDL------EKKADEVFHCPVCFKEFVCKYGLETHMETHSD-NPLRCD 238
               +  +   S             ++ + C  C K F+ K  L  H  TH+  NP +C 
Sbjct: 780 YGCSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKAFIWKSLLIVHERTHAGVNPYKCS 839

Query: 239 ICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR 296
            C  +F     LL H  +  ++ P +    G+ FI+N+  I       G   + C +  +
Sbjct: 840 QCEKSFSGKLRLLVHQRMHTREKPYECSECGKAFIRNSQLIVHQRTHSGEKPYGCNECGK 899

Query: 297 -ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHV 339
             SQ    +  +R  + +    C  C KAF     L +H++THV
Sbjct: 900 TFSQKSILSAHQRTHTGEKPCKCTECGKAFCWKSQLIMHQRTHV 943



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 87/346 (25%), Positives = 130/346 (37%), Gaps = 28/346 (8%)

Query: 38  QGIKSPSKPPGPNRIGRR---------NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQH 88
           QGI +  KP G  + G+          +Q +      Y C  C K   ++  L +H R H
Sbjct: 463 QGIHTGVKPYGCIQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKAFRSKSYLIIHTRTH 522

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE 148
              TG   H C+ CGK+ S  S L  H  +H+GE PY+C  CG++F+    +  H + H 
Sbjct: 523 ---TGEKLHECNNCGKAFSFKSQLIIHQRIHTGENPYECHECGKAFSRKYQLISHQRTHA 579

Query: 149 -KDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEV 207
            + P   T       LK + +  +R  + +   E  +   A     +          ++ 
Sbjct: 580 GEKPYECTDCGKAFGLKSQLIIHQRTHTGEKPFECSECQKAFNTKSNLIVHQRTHTGEKP 639

Query: 208 FHCPVCFKEFVCKYGLETHMETHSD-NPLRCDICCVTFRTHRGLLRHNALVHKQLPR--D 264
           + C  C K F  K  L  H   H+   P  C  C  TF     L+ H        P    
Sbjct: 640 YSCNECGKAFTFKSQLIVHKGVHTGVKPYGCSQCAKTFSLKSQLIVHQRSHTGVKPYGCS 699

Query: 265 AMGRPFIQNNPSIPAGFHDLGFTDFSCRK----FPRISQAWCETNLRRCISEQHRFVCDT 320
             G+ F   +  I       G     CR+    F   SQ       +R  + ++ + C  
Sbjct: 700 ECGKAFRSKSYLIIHMRTHTGEKPHECRECGKSFSFNSQLIVH---QRIHTGENPYECSE 756

Query: 321 CDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLAL 366
           C KAF     L  H++TH       EKP      G A   K +L +
Sbjct: 757 CGKAFNRKDQLISHQRTHAG-----EKPYGCSECGKAFSSKSYLII 797



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 79/324 (24%), Positives = 126/324 (38%), Gaps = 17/324 (5%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C+K   T+  L +H R H   TG   +SC+ CGK+ +  S L  H
Sbjct: 602 HQRTHTGEKPFECSECQKAFNTKSNLIVHQRTH---TGEKPYSCNECGKAFTFKSQLIVH 658

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRKL 174
             VH+G +PY C+ C ++F+    +  H + H    P   +        K   +   R  
Sbjct: 659 KGVHTGVKPYGCSQCAKTFSLKSQLIVHQRSHTGVKPYGCSECGKAFRSKSYLIIHMR-- 716

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHS- 231
           +H  E   E     K    + Q    ++    +  + C  C K F  K  L +H  TH+ 
Sbjct: 717 THTGEKPHECRECGKSFSFNSQLIVHQRIHTGENPYECSECGKAFNRKDQLISHQRTHAG 776

Query: 232 DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDF 289
           + P  C  C   F +   L+ H      + P +    G+ FI  +  I       G   +
Sbjct: 777 EKPYGCSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKAFIWKSLLIVHERTHAGVNPY 836

Query: 290 SCRKFPRISQAWCETNL-RRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C +  +         + +R  + +  + C  C KAF     L +H++TH       EKP
Sbjct: 837 KCSQCEKSFSGKLRLLVHQRMHTREKPYECSECGKAFIRNSQLIVHQRTH-----SGEKP 891

Query: 349 QATPLPGDALDQKGFLALLGLQHT 372
                 G    QK  L+     HT
Sbjct: 892 YGCNECGKTFSQKSILSAHQRTHT 915



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 58/183 (31%), Positives = 73/183 (39%), Gaps = 22/183 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H RSH G+ PY CN C      K+ LI H RTH+GE+ + C 
Sbjct: 472 YGCIQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKAFRSKSYLIIHTRTHTGEKLHECN 531

Query: 703 ICHYPFTVKANCERHLR------KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F+ K+    H R              K   +  + +S       +        C 
Sbjct: 532 NCGKAFSFKSQLIIHQRIHTGENPYECHECGKAFSRKYQLISHQRTHAGE----KPYECT 587

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L IH RT         H G KPFEC EC  AF  K N I H   Q  H 
Sbjct: 588 DCGKAFGLKSQLIIHQRT---------HTGEKPFECSECQKAFNTKSNLIVH---QRTHT 635

Query: 817 PEQ 819
            E+
Sbjct: 636 GEK 638



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 71/289 (24%), Positives = 112/289 (38%), Gaps = 38/289 (13%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q+T  E+  Y C  C K  +++  L +H R H   TG   H CS C K+ S  S L  H
Sbjct: 294 HQQTHAEEKPYGCNECGKDFSSKSYLIVHQRIH---TGEKLHECSECRKTFSFHSQLVIH 350

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRKL 174
             +H+GE PY+C  CG+ F+    +  H K H  + P           LK + +  +R  
Sbjct: 351 QRIHTGENPYECCECGKVFSRKDQLVSHQKTHSGQKPYVCNECGKAFGLKSQLIIHER-- 408

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DN 233
                            +  G         ++ + C  C K F  K  L  H  TH+ + 
Sbjct: 409 -----------------IHTG---------EKPYECNECQKAFNTKSNLMVHQRTHTGEK 442

Query: 234 PLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFSC 291
           P  C  C   F     L+ H  +     P   +  G+ F   +  I       G   + C
Sbjct: 443 PYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGCIQCGKGFSLKSQLIVHQRSHTGMKPYVC 502

Query: 292 RKFPRI--SQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
            +  +   S+++   + R    E+    C+ C KAF     L +H++ H
Sbjct: 503 NECGKAFRSKSYLIIHTRTHTGEK-LHECNNCGKAFSFKSQLIIHQRIH 550



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 25/190 (13%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           L+ C  C + F+F   L  H R H G +PY+C  C  + + K  L+ H +THSG++PY+C
Sbjct: 331 LHECSECRKTFSFHSQLVIHQRIHTGENPYECCECGKVFSRKDQLVSHQKTHSGQKPYVC 390

Query: 702 KICHYPFTVKANC---ER-HLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRL 757
             C   F +K+     ER H  +K  +    + +K     S+              VC  
Sbjct: 391 NECGKAFGLKSQLIIHERIHTGEKPYEC--NECQKAFNTKSNLMVHQRTHTGEKPYVCSD 448

Query: 758 CGEDLKHYRALRIHMRTH----------CGRGLG---------GGHKGRKPFECKECSAA 798
           CG+       L +H   H          CG+G             H G KP+ C EC  A
Sbjct: 449 CGKAFTFKSQLIVHQGIHTGVKPYGCIQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKA 508

Query: 799 FAAKRNCIHH 808
           F +K   I H
Sbjct: 509 FRSKSYLIIH 518



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 54/179 (30%), Positives = 74/179 (41%), Gaps = 14/179 (7%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+    L  H+R+H G  PY+CN C      K+ LI H RTH+G  PY C 
Sbjct: 780 YGCSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKAFIWKSLLIVHERTHAGVNPYKCS 839

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTV--CRLCGE 760
            C   F+ K     H R    +   +  E    ++ +S   +     + +    C  CG+
Sbjct: 840 QCEKSFSGKLRLLVHQRMHTREKPYECSECGKAFIRNSQLIVHQRTHSGEKPYGCNECGK 899

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
                  L  H RTH G          KP +C EC  AF  K   I H   Q  HV ++
Sbjct: 900 TFSQKSILSAHQRTHTGE---------KPCKCTECGKAFCWKSQLIMH---QRTHVDDK 946



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 53/180 (29%), Positives = 75/180 (41%), Gaps = 38/180 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + CR C + F+F+  L  H R H G +PY+C+ C      K  LI H RTH+GE+PY C 
Sbjct: 724 HECRECGKSFSFNSQLIVHQRIHTGENPYECSECGKAFNRKDQLISHQRTHAGEKPYGCS 783

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+    H+R           EK  E                   C  CG+  
Sbjct: 784 ECGKAFSSKSYLIIHMR-------THSGEKPYE-------------------CNECGKAF 817

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
                L +H RTH          G  P++C +C  +F+ K   + H   Q +H  E+  E
Sbjct: 818 IWKSLLIVHERTHA---------GVNPYKCSQCEKSFSGKLRLLVH---QRMHTREKPYE 865



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 52/167 (31%), Positives = 66/167 (39%), Gaps = 35/167 (20%)

Query: 642 LYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYIC 701
           L+ C  C + F+F   L  H R H G +PY+C+ C    + K  LI H RTH+GE+PY C
Sbjct: 527 LHECNNCGKAFSFKSQLIIHQRIHTGENPYECHECGKAFSRKYQLISHQRTHAGEKPYEC 586

Query: 702 KICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGED 761
             C   F +K+    H R           EK  E                   C  C + 
Sbjct: 587 TDCGKAFGLKSQLIIHQR-------THTGEKPFE-------------------CSECQKA 620

Query: 762 LKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
                 L +H RT         H G KP+ C EC  AF  K   I H
Sbjct: 621 FNTKSNLIVHQRT---------HTGEKPYSCNECGKAFTFKSQLIVH 658



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 83/382 (21%), Positives = 130/382 (34%), Gaps = 27/382 (7%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L  H  THTG+KPF C +C   F+TKSN   HQ    G    S    
Sbjct: 586  CTDCGKAFGLKSQLIIHQRTHTGEKPFECSECQKAFNTKSNLIVHQRTHTGEKPYSCNEC 645

Query: 1308 GLIPQSKESDV---GSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDA 1364
            G     K   +   G H        ++ A        L    R       T ++      
Sbjct: 646  GKAFTFKSQLIVHKGVHTGVKPYGCSQCAKTFSLKSQLIVHQRSH-----TGVKPYGCSE 700

Query: 1365 PVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKL 1424
              +   +++   +H   H   + HE  E   +          +   +     +     K 
Sbjct: 701  CGKAFRSKSYLIIHMRTHTGEKPHECRECGKSFSFNSQLIVHQRIHTGENPYECSECGKA 760

Query: 1425 MDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGAS 1484
             + K    D         + E+   C  CGK+F     L  H + H  ++P +    G +
Sbjct: 761  FNRK----DQLISHQRTHAGEKPYGCSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKA 816

Query: 1485 TAEEGPQPAPEQEEKP--PETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEK--RS 1540
               +      E+      P   ++  +S  G       +     E P +     +   R+
Sbjct: 817  FIWKSLLIVHERTHAGVNPYKCSQCEKSFSGKLRLLVHQRMHTREKPYECSECGKAFIRN 876

Query: 1541 SEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTC 1600
            S+     +    + P             C+ C K F     L+ H R+HTGE+P KC  C
Sbjct: 877  SQLIVHQRTHSGEKPYG-----------CNECGKTFSQKSILSAHQRTHTGEKPCKCTEC 925

Query: 1601 ERTFTLKHSLVRHQRIHQKARH 1622
             + F  K  L+ HQR H   +H
Sbjct: 926  GKAFCWKSQLIMHQRTHVDDKH 947



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 55/190 (28%), Positives = 72/190 (37%), Gaps = 27/190 (14%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F F   L  H   H G+ PY C+ C    + K+ LI H R+H+G +PY C 
Sbjct: 640 YSCNECGKAFTFKSQLIVHKGVHTGVKPYGCSQCAKTFSLKSQLIVHQRSHTGVKPYGCS 699

Query: 703 ICHYPFTVKANCERHLR-----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRL 757
            C   F  K+    H+R     K H     ++  K+  + S                C  
Sbjct: 700 ECGKAFRSKSYLIIHMRTHTGEKPH---ECRECGKSFSFNSQLIVHQRIHTGENPYECSE 756

Query: 758 CGEDLKHYRALRIHMRTH----------CGRGLGG---------GHKGRKPFECKECSAA 798
           CG+       L  H RTH          CG+              H G KP+EC EC  A
Sbjct: 757 CGKAFNRKDQLISHQRTHAGEKPYGCSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKA 816

Query: 799 FAAKRNCIHH 808
           F  K   I H
Sbjct: 817 FIWKSLLIVH 826



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 55/196 (28%), Positives = 71/196 (36%), Gaps = 48/196 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F     L  H R+H G  PY CN C      K+ LI H   H+G +PY C 
Sbjct: 612 FECSECQKAFNTKSNLIVHQRTHTGEKPYSCNECGKAFTFKSQLIVHKGVHTGVKPYGCS 671

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F++K+    H R                  S +  +           C  CG+  
Sbjct: 672 QCAKTFSLKSQLIVHQR------------------SHTGVKPYG--------CSECGKAF 705

Query: 763 KHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFAAKR 803
           +    L IHMRTH          CG+              H G  P+EC EC  AF  K 
Sbjct: 706 RSKSYLIIHMRTHTGEKPHECRECGKSFSFNSQLIVHQRIHTGENPYECSECGKAFNRKD 765

Query: 804 NCIHHILKQHLHVPEQ 819
             I H   Q  H  E+
Sbjct: 766 QLISH---QRTHAGEK 778



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 98/431 (22%), Positives = 146/431 (33%), Gaps = 48/431 (11%)

Query: 1243 LQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTC 1302
            ++   C  C + F   S L  H  THTG+K   C  C   FS KS    HQ    G    
Sbjct: 497  MKPYVCNECGKAFRSKSYLIIHTRTHTGEKLHECNNCGKAFSFKSQLIIHQRIHTGENPY 556

Query: 1303 SLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAG 1362
                 G    S++  + SH  T +          G+   L S       +     R   G
Sbjct: 557  ECHECGKA-FSRKYQLISHQRTHAGEKPYECTDCGKAFGLKS-------QLIIHQRTHTG 608

Query: 1363 DAPVEQATAETASPVHREEHGRGESHEPEEEHGTEES-------------TGDADGAEED 1409
            + P E +  + A            +H  E+ +   E               G   G +  
Sbjct: 609  EKPFECSECQKAFNTKSNLIVHQRTHTGEKPYSCNECGKAFTFKSQLIVHKGVHTGVKPY 668

Query: 1410 ASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKA 1469
              S  +      ++L+  + +            +  +   C  CGK+F+    L  H + 
Sbjct: 669  GCSQCAKTFSLKSQLIVHQRSH-----------TGVKPYGCSECGKAFRSKSYLIIHMRT 717

Query: 1470 HGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGP 1529
            H  ++P + +  G S +    Q    Q     E P E  E              + T   
Sbjct: 718  HTGEKPHECRECGKSFSFNS-QLIVHQRIHTGENPYECSECGKAFNRKDQLISHQRTHAG 776

Query: 1530 SD--GESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMR 1587
                G S   K  S KS      +T S         ++   C+ C K F     L  H R
Sbjct: 777  EKPYGCSECGKAFSSKSYLIIHMRTHS--------GEKPYECNECGKAFIWKSLLIVHER 828

Query: 1588 SHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHHGKDSDKEERGEEDSENEST 1645
            +H G  PYKC  CE++F+ K  L+ HQR+H  +K       GK      R  +   ++ T
Sbjct: 829  THAGVNPYKCSQCEKSFSGKLRLLVHQRMHTREKPYECSECGK---AFIRNSQLIVHQRT 885

Query: 1646 HSGNNAVSENE 1656
            HSG      NE
Sbjct: 886  HSGEKPYGCNE 896



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 51/183 (27%), Positives = 69/183 (37%), Gaps = 22/183 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H ++H    PY CN C    + K+ LI H R H+GE+ + C 
Sbjct: 276 FGCSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKDFSSKSYLIVHQRIHTGEKLHECS 335

Query: 703 ICHYPFTVKANCERHLR------KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCR 756
            C   F+  +    H R              K   +  + VS               VC 
Sbjct: 336 ECRKTFSFHSQLVIHQRIHTGENPYECCECGKVFSRKDQLVSHQKTHSGQ----KPYVCN 391

Query: 757 LCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            CG+       L IH R          H G KP+EC EC  AF  K N + H   Q  H 
Sbjct: 392 ECGKAFGLKSQLIIHERI---------HTGEKPYECNECQKAFNTKSNLMVH---QRTHT 439

Query: 817 PEQ 819
            E+
Sbjct: 440 GEK 442



 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 89/383 (23%), Positives = 139/383 (36%), Gaps = 39/383 (10%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L  H   HTG+K   C +C   FS  S    HQ    G         
Sbjct: 306  CNECGKDFSSKSYLIVHQRIHTGEKLHECSECRKTFSFHSQLVIHQRIHTGENPYECCEC 365

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G +   K+  V SH  T S          G+   L S       +     R   G+ P E
Sbjct: 366  GKVFSRKDQLV-SHQKTHSGQKPYVCNECGKAFGLKS-------QLIIHERIHTGEKPYE 417

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
                + A            +H  E+ +   +  G A   +     +Q +     T +  +
Sbjct: 418  CNECQKAFNTKSNLMVHQRTHTGEKPYVCSDC-GKAFTFKSQLIVHQGIH----TGVKPY 472

Query: 1428 KLAEGDGEAGAGGAASQE-----------QKLACDTCGKSFKFLGTLSRHRKAHGRQEPK 1476
                G  + G G +   +           +   C+ CGK+F+    L  H + H  ++  
Sbjct: 473  ----GCIQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKAFRSKSYLIIHTRTHTGEKLH 528

Query: 1477 DEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAA 1536
            +    G + + +  Q    Q     E P E  E     G+A + K     +  S   + A
Sbjct: 529  ECNNCGKAFSFKS-QLIIHQRIHTGENPYECHE----CGKAFSRKY----QLISHQRTHA 579

Query: 1537 EKRSSEKSDDDKKPKTDSPKSVASKADKRKKV--CSVCNKRFWSLQDLTRHMRSHTGERP 1594
             ++  E +D  K     S   +  +    +K   CS C K F +  +L  H R+HTGE+P
Sbjct: 580  GEKPYECTDCGKAFGLKSQLIIHQRTHTGEKPFECSECQKAFNTKSNLIVHQRTHTGEKP 639

Query: 1595 YKCQTCERTFTLKHSLVRHQRIH 1617
            Y C  C + FT K  L+ H+ +H
Sbjct: 640  YSCNECGKAFTFKSQLIVHKGVH 662



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  Y C  C K      QL +H R H+   G   + C+ CGK+ S  S L  H
Sbjct: 854 HQRMHTREKPYECSECGKAFIRNSQLIVHQRTHS---GEKPYGCNECGKTFSQKSILSAH 910

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
              H+GE+P KCT CG++F     +  H + H  D
Sbjct: 911 QRTHTGEKPCKCTECGKAFCWKSQLIMHQRTHVDD 945



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 64/256 (25%), Positives = 100/256 (39%), Gaps = 15/256 (5%)

Query: 93  GGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPN 152
           G     CS C K+ SS S L  H   H+ E+PY C  CG+ F++   +  H +IH  +  
Sbjct: 272 GEKPFGCSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKDFSSKSYLIVHQRIHTGEKL 331

Query: 153 SATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHC 210
              +    +     +L   +++ H  E+  E     K      Q    +K     + + C
Sbjct: 332 HECSECRKTFSFHSQLVIHQRI-HTGENPYECCECGKVFSRKDQLVSHQKTHSGQKPYVC 390

Query: 211 PVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPR--DAMG 267
             C K F  K  L  H   H+ + P  C+ C   F T   L+ H      + P      G
Sbjct: 391 NECGKAFGLKSQLIIHERIHTGEKPYECNECQKAFNTKSNLMVHQRTHTGEKPYVCSDCG 450

Query: 268 RPF-IQNNPSIPAGFHDLGFTDFSC----RKFPRISQAWCETNLRRCISEQHRFVCDTCD 322
           + F  ++   +  G H  G   + C    + F   SQ       +R  +    +VC+ C 
Sbjct: 451 KAFTFKSQLIVHQGIH-TGVKPYGCIQCGKGFSLKSQLIVH---QRSHTGMKPYVCNECG 506

Query: 323 KAFPMLCSLALHKQTH 338
           KAF     L +H +TH
Sbjct: 507 KAFRSKSYLIIHTRTH 522



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 57/209 (27%), Positives = 77/209 (36%), Gaps = 36/209 (17%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     ++ Y C  C K    + QL  H R H    G   + CS CGK+ SS S L  H
Sbjct: 742 HQRIHTGENPYECSECGKAFNRKDQLISHQRTH---AGEKPYGCSECGKAFSSKSYLIIH 798

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEK-DPNSATATAPPSPLKRRRLSSKRKL 174
           M  HSGE+PY+C  CG++F     +  H + H   +P   +        K R L  +R  
Sbjct: 799 MRTHSGEKPYECNECGKAFIWKSLLIVHERTHAGVNPYKCSQCEKSFSGKLRLLVHQRM- 857

Query: 175 SHDAESEREDPAPAKKMVEDGQ--------SGDLEKKADEV------------------- 207
            H  E   E     K  + + Q        SG+     +E                    
Sbjct: 858 -HTREKPYECSECGKAFIRNSQLIVHQRTHSGEKPYGCNECGKTFSQKSILSAHQRTHTG 916

Query: 208 ---FHCPVCFKEFVCKYGLETHMETHSDN 233
                C  C K F  K  L  H  TH D+
Sbjct: 917 EKPCKCTECGKAFCWKSQLIMHQRTHVDD 945



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 5/103 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            CS C K F S   L  HMR+HTGE+P++C+ C ++F+    L+ HQRIH  +        
Sbjct: 698  CSECGKAFRSKSYLIIHMRTHTGEKPHECRECGKSFSFNSQLIVHQRIHTGENPYECSEC 757

Query: 1627 GKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAV 1669
            GK  +   R ++   ++ TH+G      +E   A ++ +++ +
Sbjct: 758  GKAFN---RKDQLISHQRTHAGEKPYGCSECGKAFSSKSYLII 797



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 30/81 (37%), Positives = 39/81 (48%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           R+  Y C  C + F  +  L  H R+H G  PY CN C    + K+ L  H RTH+GE+P
Sbjct: 860 REKPYECSECGKAFIRNSQLIVHQRTHSGEKPYGCNECGKTFSQKSILSAHQRTHTGEKP 919

Query: 699 YICKICHYPFTVKANCERHLR 719
             C  C   F  K+    H R
Sbjct: 920 CKCTECGKAFCWKSQLIMHQR 940



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 27/136 (19%)

Query: 1568 VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQ--------- 1618
            VC+ C K F S   L  H R+HTGE+ ++C  C + F+ K  L+ HQRIH          
Sbjct: 501  VCNECGKAFRSKSYLIIHTRTHTGEKLHECNNCGKAFSFKSQLIIHQRIHTGENPYECHE 560

Query: 1619 --KARHAKHHGKDSDKEERGEEDSE----------------NESTHSGNNAVSENEAELA 1660
              KA   K+      +   GE+  E                ++ TH+G      +E + A
Sbjct: 561  CGKAFSRKYQLISHQRTHAGEKPYECTDCGKAFGLKSQLIIHQRTHTGEKPFECSECQKA 620

Query: 1661 PNASNHMAVTRSRKEG 1676
             N  +++ V +    G
Sbjct: 621  FNTKSNLIVHQRTHTG 636



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 5/97 (5%)

Query: 1562 ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QK 1619
            A+++   C+ C K F S   L  H R HTGE+ ++C  C +TF+    LV HQRIH  + 
Sbjct: 299  AEEKPYGCNECGKDFSSKSYLIVHQRIHTGEKLHECSECRKTFSFHSQLVIHQRIHTGEN 358

Query: 1620 ARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENE 1656
                   GK      R ++   ++ THSG      NE
Sbjct: 359  PYECCECGK---VFSRKDQLVSHQKTHSGQKPYVCNE 392



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 22/49 (44%), Positives = 28/49 (57%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            CS C K F S   L  H ++H  E+PY C  C + F+ K  L+ HQRIH
Sbjct: 278  CSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKDFSSKSYLIVHQRIH 326



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 24/62 (38%), Positives = 29/62 (46%), Gaps = 2/62 (3%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C  C K F     L  H RSHTG +PY C  C + F  K  L+ H R H  +K     + 
Sbjct: 474  CIQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKAFRSKSYLIIHTRTHTGEKLHECNNC 533

Query: 1627 GK 1628
            GK
Sbjct: 534  GK 535



 Score = 38.1 bits (87), Expect = 0.075
 Identities = 18/46 (39%), Positives = 23/46 (50%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   S L  H  TH  +KP+ C +C   FS+KS    HQ
Sbjct: 278  CSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKDFSSKSYLIVHQ 323



 Score = 35.0 bits (79), Expect = 0.64
 Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 2/43 (4%)

Query: 1589 HTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHHGKD 1629
            + GE+P+ C  CE+ F+ K  L+ HQ+ H  +K       GKD
Sbjct: 270  YMGEKPFGCSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKD 312


>gi|28274682 zinc finger protein 33A isoform b [Homo sapiens]
          Length = 810

 Score =  103 bits (257), Expect = 1e-21
 Identities = 84/326 (25%), Positives = 128/326 (39%), Gaps = 21/326 (6%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  Y C  C K    +  LT H R H   TG   + C  CGKS    S L  H
Sbjct: 402 HQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTH---TGLKPYECYECGKSFRVTSHLKVH 458

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+P++C  CG+SF+   N+ +H +IH  D  S    A       + L ++ ++ 
Sbjct: 459 QRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGD-KSYECNACGKTFYHKSLLTRHQII 517

Query: 176 HDAESEREDPAPAKK--MVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           H      E     K   +  D           + F CP C K F  K  L  H  TH+ +
Sbjct: 518 HTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGE 577

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFS 290
            P  C  C   F     L +HN     + P +    G+ F Q +         +G   + 
Sbjct: 578 KPYECHECGKIFYNKSYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYK 637

Query: 291 CRKFPRISQAWCETNL----RRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQE 346
           C +     +A+C  +     +R  +++  + C+ C K+F +   L  H++ H       E
Sbjct: 638 CNE---CGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTG-----E 689

Query: 347 KPQATPLPGDALDQKGFLALLGLQHT 372
           KP      G     K  L +    HT
Sbjct: 690 KPYECNECGKFFRHKSSLTVHHRAHT 715



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 55/180 (30%), Positives = 76/180 (42%), Gaps = 38/180 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F     L  H RSH G  P++CN C    + K+AL  H RTH+GE+PY C 
Sbjct: 356 FQCNECEKAFWDKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCN 415

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++  +H R        K  E                       C  CG+  
Sbjct: 416 ACGKTFCQKSDLTKHQR---THTGLKPYE-----------------------CYECGKSF 449

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
           +    L++H RT         H G KPFEC EC  +F+ K N   H   Q +H+ ++  E
Sbjct: 450 RVTSHLKVHQRT---------HTGEKPFECLECGKSFSEKSNLTQH---QRIHIGDKSYE 497



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 85/333 (25%), Positives = 129/333 (38%), Gaps = 29/333 (8%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           R+Q     +  + C  CEK    +  LT H R H   TG     C+ CGK+ S  S+L  
Sbjct: 345 RHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSH---TGEKPFECNECGKAFSHKSALTL 401

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPL---KRRRLSSK 171
           H   H+GE+PY+C  CG++F    ++ +H + H       T   P       K  R++S 
Sbjct: 402 HQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTH-------TGLKPYECYECGKSFRVTSH 454

Query: 172 RKL---SHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETH 226
            K+   +H  E   E     K   E       ++    D+ + C  C K F  K  L  H
Sbjct: 455 LKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYECNACGKTFYHKSLLTRH 514

Query: 227 METHSD-NPLRCDICCVTFRTHRGLLRHNALVHKQLP--RDAMGRPFIQNNPSIPAGFHD 283
              H+   P  C  C  TF     L  H      Q P      G+ F   +         
Sbjct: 515 QIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTH 574

Query: 284 LGFTDFSCRKFPRI--SQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAA 341
            G   + C +  +I  ++++  T   R  + +  + C+ C KAF     L  H++ H+  
Sbjct: 575 TGEKPYECHECGKIFYNKSYL-TKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIG- 632

Query: 342 DQGQEKPQATPLPGDALDQKGFLALLGLQHTKD 374
               EKP      G A   K  L +    HT++
Sbjct: 633 ----EKPYKCNECGKAFCHKSALIVHQRTHTQE 661



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 61/195 (31%), Positives = 76/195 (38%), Gaps = 48/195 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R H+G  PY+CN C      K+ALI H RTH+ E+PY C 
Sbjct: 608 YECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQRTHTQEKPYKCN 667

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F VK+    H RK          EK  E                   C  CG+  
Sbjct: 668 ECGKSFCVKSGLIFHERK-------HTGEKPYE-------------------CNECGKFF 701

Query: 763 KHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAFAAKR 803
           +H  +L +H R H          CG+              H G KP+EC  C   F+ K 
Sbjct: 702 RHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKS 761

Query: 804 NCIHHILKQHLHVPE 818
           N I H   Q  H+ E
Sbjct: 762 NLIVH---QRRHIGE 773



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 90/382 (23%), Positives = 138/382 (36%), Gaps = 51/382 (13%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L RH   HTGQKPF C +C+  F  KSN  +HQ    G         
Sbjct: 330  CNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECNEC 389

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVL----DLTSRDREQPSEGATELRQVAGD 1363
            G    S +S +  H  T +        A G+      DLT   R        E  +    
Sbjct: 390  GKA-FSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTHTGLKPYECYECGKS 448

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
              V           H + H R  +H  E+     E  G +   + + + +Q + +     
Sbjct: 449  FRVTS---------HLKVHQR--THTGEKPFECLEC-GKSFSEKSNLTQHQRIHIG---- 492

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGA 1483
                                 ++   C+ CGK+F     L+RH+  H   +P +    G 
Sbjct: 493  ---------------------DKSYECNACGKTFYHKSLLTRHQIIHTGWKPYECYECGK 531

Query: 1484 STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLA-EETEGPSDGESAAEKRSSE 1542
            +   +      ++     +  A      P  G+  + K    +      GE   E     
Sbjct: 532  TFCLKSDLTVHQRTHTGQKPFA-----CPECGKFFSHKSTLSQHYRTHTGEKPYECHECG 586

Query: 1543 KSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCER 1602
            K   +K   T   K   +   ++   C+ C K F+    LT+H R H GE+PYKC  C +
Sbjct: 587  KIFYNKSYLT---KHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGK 643

Query: 1603 TFTLKHSLVRHQRIHQKARHAK 1624
             F  K +L+ HQR H + +  K
Sbjct: 644  AFCHKSALIVHQRTHTQEKPYK 665



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 97/391 (24%), Positives = 141/391 (36%), Gaps = 73/391 (18%)

Query: 1243 LQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTC 1302
            L+   C  C + F   S L+ H  THTG+KPF C +C   FS KSN  +HQ    G  + 
Sbjct: 437  LKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSY 496

Query: 1303 SLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAG 1362
                 G     K S +  H    +          G+   L S                  
Sbjct: 497  ECNACGKTFYHK-SLLTRHQIIHTGWKPYECYECGKTFCLKS------------------ 537

Query: 1363 DAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFAT 1422
            D  V Q T     P    E G+  SH+          TG+    E         +  + T
Sbjct: 538  DLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGEKP-YECHECGKIFYNKSYLT 596

Query: 1423 KLMDFKLAEGDGEAGAGGAA-------SQEQKL-------ACDTCGKSFKFLGTLSRHRK 1468
            K       E   E    G A       +Q Q++        C+ CGK+F     L  H++
Sbjct: 597  KHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQR 656

Query: 1469 AHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEG 1528
             H +++P      G S   +      E++                 GE P          
Sbjct: 657  THTQEKPYKCNECGKSFCVKSGLIFHERKH---------------TGEKP---------- 691

Query: 1529 PSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKK--VCSVCNKRFWSLQDLTRHM 1586
                         E ++  K  +  S  +V  +A   +K   C+ C K F+   +L +H 
Sbjct: 692  ------------YECNECGKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQ 739

Query: 1587 RSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            RSHTGE+PY+C TC +TF+ K +L+ HQR H
Sbjct: 740  RSHTGEKPYECNTCRKTFSQKSNLIVHQRRH 770



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 70/317 (22%), Positives = 121/317 (38%), Gaps = 36/317 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C K  + +  LT H R H    G   + C+ CGK+    S L RH
Sbjct: 458 HQRTHTGEKPFECLECGKSFSEKSNLTQHQRIH---IGDKSYECNACGKTFYHKSLLTRH 514

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD-----PNSATATAPPSPLKR----- 165
            ++H+G +PY+C  CG++F    ++  H + H        P      +  S L +     
Sbjct: 515 QIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTH 574

Query: 166 -----------------RRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKK--ADE 206
                            +   +K   +H  E   E     K   +  Q    ++    ++
Sbjct: 575 TGEKPYECHECGKIFYNKSYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEK 634

Query: 207 VFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA 265
            + C  C K F  K  L  H  TH+ + P +C+ C  +F    GL+ H      + P + 
Sbjct: 635 PYKCNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYEC 694

Query: 266 --MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCE-TNLRRCISEQHRFVCDTCD 322
              G+ F   +          G     C +  +I     E    +R  + +  + C+TC 
Sbjct: 695 NECGKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCR 754

Query: 323 KAFPMLCSLALHKQTHV 339
           K F    +L +H++ H+
Sbjct: 755 KTFSQKSNLIVHQRRHI 771



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 49/168 (29%), Positives = 67/168 (39%), Gaps = 11/168 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PYQCN C      K+ L +H RTH+G +PY C 
Sbjct: 384 FECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTHTGLKPYECY 443

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F V ++ + H R    +   + +E    +   S           D    C  CG+
Sbjct: 444 ECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYECNACGK 503

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
              H   L  H            H G KP+EC EC   F  K +   H
Sbjct: 504 TFYHKSLLTRHQII---------HTGWKPYECYECGKTFCLKSDLTVH 542



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 54/188 (28%), Positives = 74/188 (39%), Gaps = 22/188 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  P+ C  C    + K+ L +H RTH+GE+PY C 
Sbjct: 524 YECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECH 583

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F  K+   +H R    +   +  E    +   S           +    C  CG+
Sbjct: 584 ECGKIFYNKSYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGK 643

Query: 761 DLKHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAFAA 801
              H  AL +H RTH          CG+              H G KP+EC EC   F  
Sbjct: 644 AFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRH 703

Query: 802 KRN-CIHH 808
           K +  +HH
Sbjct: 704 KSSLTVHH 711



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 70/294 (23%), Positives = 112/294 (38%), Gaps = 24/294 (8%)

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
           D G     C+ CGK+    S L RH  VH+G++P++C  C ++F    N+ +H + H  +
Sbjct: 322 DKGEKHFECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGE 381

Query: 151 PNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKAD----- 205
                     +   +  L+  ++ +H  E   +  A  K      Q  DL K        
Sbjct: 382 KPFECNECGKAFSHKSALTLHQR-THTGEKPYQCNACGKTFC---QKSDLTKHQRTHTGL 437

Query: 206 EVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNA--LVHKQLP 262
           + + C  C K F     L+ H  TH+ + P  C  C  +F     L +H    +  K   
Sbjct: 438 KPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYE 497

Query: 263 RDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWC----ETNLRRCISEQHRFVC 318
            +A G+ F   +          G+  + C +     + +C     T  +R  + Q  F C
Sbjct: 498 CNACGKTFYHKSLLTRHQIIHTGWKPYECYE---CGKTFCLKSDLTVHQRTHTGQKPFAC 554

Query: 319 DTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
             C K F    +L+ H +TH       EKP      G     K +L      HT
Sbjct: 555 PECGKFFSHKSTLSQHYRTHTG-----EKPYECHECGKIFYNKSYLTKHNRTHT 603



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 51/177 (28%), Positives = 68/177 (38%), Gaps = 38/177 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F    +L  H   H G  PY+C  C      K+ L  H RTH+G++P+ C 
Sbjct: 496 YECNACGKTFYHKSLLTRHQIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACP 555

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+   +H R           EK  E                   C  CG+  
Sbjct: 556 ECGKFFSHKSTLSQHYR-------THTGEKPYE-------------------CHECGKIF 589

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
            +   L  H RT         H G KP+EC EC  AF  K     H   Q +H+ E+
Sbjct: 590 YNKSYLTKHNRT---------HTGEKPYECNECGKAFYQKSQLTQH---QRIHIGEK 634



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 51/178 (28%), Positives = 76/178 (42%), Gaps = 17/178 (9%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C+ CGK+F     L+RH++ H  Q+P  +  +      +       Q     E P
Sbjct: 325  EKHFECNECGKAFWEKSHLTRHQRVHTGQKP-FQCNECEKAFWDKSNLTKHQRSHTGEKP 383

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGE-----SAAEKRSSEKSDDDKKPKTDSPKSVA 1559
             E  E         A  L + T     GE     +A  K   +KSD  K  +T +     
Sbjct: 384  FECNECGKAFSHKSALTLHQRTH---TGEKPYQCNACGKTFCQKSDLTKHQRTHT----- 435

Query: 1560 SKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                 +   C  C K F     L  H R+HTGE+P++C  C ++F+ K +L +HQRIH
Sbjct: 436  ---GLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIH 490



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 5/110 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C+ C K FW   +LT+H RSHTGE+P++C  C + F+ K +L  HQR H  +K       
Sbjct: 358  CNECEKAFWDKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNAC 417

Query: 1627 GKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEG 1676
            GK   ++    + ++++ TH+G       E   +   ++H+ V +    G
Sbjct: 418  GKTFCQK---SDLTKHQRTHTGLKPYECYECGKSFRVTSHLKVHQRTHTG 464



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 28/59 (47%), Positives = 37/59 (62%), Gaps = 2/59 (3%)

Query: 1561 KADKRKK--VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            K DK +K   C+ C K FW    LTRH R HTG++P++C  CE+ F  K +L +HQR H
Sbjct: 320  KGDKGEKHFECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSH 378



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 42/140 (30%), Positives = 57/140 (40%), Gaps = 2/140 (1%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H    PY+CN C      K+ LI H R H+GE+PY C 
Sbjct: 636 YKCNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECN 695

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIE-KNIEYVSSSAAELVDAFCAPDTV-CRLCGE 760
            C   F  K++   H R    + + +  E   I Y  S  A+   +        C  C +
Sbjct: 696 ECGKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRK 755

Query: 761 DLKHYRALRIHMRTHCGRGL 780
                  L +H R H G  L
Sbjct: 756 TFSQKSNLIVHQRRHIGENL 775



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 68/330 (20%), Positives = 115/330 (34%), Gaps = 31/330 (9%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q +    + Y    CEK    +  L+   + H       D  C   G +      L   
Sbjct: 264 HQISPSRDNHYEFSDCEKFLCVKSTLS---KPHGVSMKHYD--CGESGNNFRRKLCLSHL 318

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
                GE+ ++C  CG++F    ++ RH ++H             +   +  L +K + S
Sbjct: 319 QKGDKGEKHFECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNL-TKHQRS 377

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHSD- 232
           H  E   E     K           ++    ++ + C  C K F  K  L  H  TH+  
Sbjct: 378 HTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTHTGL 437

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFS 290
            P  C  C  +FR    L  H      + P + +  G+ F + +         +G   + 
Sbjct: 438 KPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYE 497

Query: 291 CRKFPRISQAWCETNLRRCISEQHRFV--------CDTCDKAFPMLCSLALHKQTHVAAD 342
           C        A  +T   + +  +H+ +        C  C K F +   L +H++TH    
Sbjct: 498 C-------NACGKTFYHKSLLTRHQIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTG-- 548

Query: 343 QGQEKPQATPLPGDALDQKGFLALLGLQHT 372
              +KP A P  G     K  L+     HT
Sbjct: 549 ---QKPFACPECGKFFSHKSTLSQHYRTHT 575



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 22/51 (43%), Positives = 28/51 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHG 1298
            C  C ++F   S L +H  +HTG+KP+ C  C   FS KSN   HQ R  G
Sbjct: 722  CNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRRHIG 772



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/112 (25%), Positives = 41/112 (36%), Gaps = 5/112 (4%)

Query: 1182 EKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTN 1241
            +K  A  +  KF     T   + +      P + H     E G    +K    K N    
Sbjct: 549  QKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECH-----ECGKIFYNKSYLTKHNRTHT 603

Query: 1242 CLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
              +   C  C + F   S L +H   H G+KP+ C +C   F  KS    HQ
Sbjct: 604  GEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQ 655



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 52/230 (22%), Positives = 83/230 (36%), Gaps = 53/230 (23%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           RK+   C  C   F     L     ++LG    + N C  +  +    I+H  TH+ E+ 
Sbjct: 135 RKMFCQCDSCGMSFNTVSELVISKINYLGKKSDEFNACGKLLLN----IKHDETHTQEKN 190

Query: 699 YICK----ICHYPFTVKAN-------------CERHLRKKHLKATRKDI---EKNIEY-- 736
            + K    + H+  T++               C+  L +K +  T+K     E N +Y  
Sbjct: 191 EVLKNRNTLSHHEETLQHEKIQTLEHNFEYSICQETLLEKAVFNTQKRENAEENNCDYNE 250

Query: 737 ---------------VSSSA------AELVDAFCAPDTVCRLCGEDLKHY---RALRIHM 772
                          +S S       ++     C   T+ +  G  +KHY    +     
Sbjct: 251 FGRTLCDSSSLLFHQISPSRDNHYEFSDCEKFLCVKSTLSKPHGVSMKHYDCGESGNNFR 310

Query: 773 RTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
           R  C   L  G KG K FEC EC  AF  K +   H   Q +H  ++  +
Sbjct: 311 RKLCLSHLQKGDKGEKHFECNECGKAFWEKSHLTRH---QRVHTGQKPFQ 357



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 63  KSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGE 122
           + S  C  C KI   + +L  H R H   TG   + C+ C K+ S  S+L  H   H GE
Sbjct: 717 EKSCQCNECGKIFYRKSELAQHQRSH---TGEKPYECNTCRKTFSQKSNLIVHQRRHIGE 773



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 15/49 (30%), Positives = 22/49 (44%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            C      F     L+   +   GE+ ++C  C + F  K  L RHQR+H
Sbjct: 302  CGESGNNFRRKLCLSHLQKGDKGEKHFECNECGKAFWEKSHLTRHQRVH 350


>gi|110347446 zinc finger protein 33A isoform a [Homo sapiens]
          Length = 811

 Score =  103 bits (257), Expect = 1e-21
 Identities = 84/326 (25%), Positives = 128/326 (39%), Gaps = 21/326 (6%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  Y C  C K    +  LT H R H   TG   + C  CGKS    S L  H
Sbjct: 403 HQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTH---TGLKPYECYECGKSFRVTSHLKVH 459

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
              H+GE+P++C  CG+SF+   N+ +H +IH  D  S    A       + L ++ ++ 
Sbjct: 460 QRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGD-KSYECNACGKTFYHKSLLTRHQII 518

Query: 176 HDAESEREDPAPAKK--MVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
           H      E     K   +  D           + F CP C K F  K  L  H  TH+ +
Sbjct: 519 HTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGE 578

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFS 290
            P  C  C   F     L +HN     + P +    G+ F Q +         +G   + 
Sbjct: 579 KPYECHECGKIFYNKSYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYK 638

Query: 291 CRKFPRISQAWCETNL----RRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQE 346
           C +     +A+C  +     +R  +++  + C+ C K+F +   L  H++ H       E
Sbjct: 639 CNE---CGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTG-----E 690

Query: 347 KPQATPLPGDALDQKGFLALLGLQHT 372
           KP      G     K  L +    HT
Sbjct: 691 KPYECNECGKFFRHKSSLTVHHRAHT 716



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 55/180 (30%), Positives = 76/180 (42%), Gaps = 38/180 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F     L  H RSH G  P++CN C    + K+AL  H RTH+GE+PY C 
Sbjct: 357 FQCNECEKAFWDKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCN 416

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++  +H R        K  E                       C  CG+  
Sbjct: 417 ACGKTFCQKSDLTKHQR---THTGLKPYE-----------------------CYECGKSF 450

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
           +    L++H RT         H G KPFEC EC  +F+ K N   H   Q +H+ ++  E
Sbjct: 451 RVTSHLKVHQRT---------HTGEKPFECLECGKSFSEKSNLTQH---QRIHIGDKSYE 498



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 85/333 (25%), Positives = 129/333 (38%), Gaps = 29/333 (8%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           R+Q     +  + C  CEK    +  LT H R H   TG     C+ CGK+ S  S+L  
Sbjct: 346 RHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSH---TGEKPFECNECGKAFSHKSALTL 402

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPL---KRRRLSSK 171
           H   H+GE+PY+C  CG++F    ++ +H + H       T   P       K  R++S 
Sbjct: 403 HQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTH-------TGLKPYECYECGKSFRVTSH 455

Query: 172 RKL---SHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETH 226
            K+   +H  E   E     K   E       ++    D+ + C  C K F  K  L  H
Sbjct: 456 LKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYECNACGKTFYHKSLLTRH 515

Query: 227 METHSD-NPLRCDICCVTFRTHRGLLRHNALVHKQLP--RDAMGRPFIQNNPSIPAGFHD 283
              H+   P  C  C  TF     L  H      Q P      G+ F   +         
Sbjct: 516 QIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTH 575

Query: 284 LGFTDFSCRKFPRI--SQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAA 341
            G   + C +  +I  ++++  T   R  + +  + C+ C KAF     L  H++ H+  
Sbjct: 576 TGEKPYECHECGKIFYNKSYL-TKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIG- 633

Query: 342 DQGQEKPQATPLPGDALDQKGFLALLGLQHTKD 374
               EKP      G A   K  L +    HT++
Sbjct: 634 ----EKPYKCNECGKAFCHKSALIVHQRTHTQE 662



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 61/195 (31%), Positives = 76/195 (38%), Gaps = 48/195 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R H+G  PY+CN C      K+ALI H RTH+ E+PY C 
Sbjct: 609 YECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQRTHTQEKPYKCN 668

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F VK+    H RK          EK  E                   C  CG+  
Sbjct: 669 ECGKSFCVKSGLIFHERK-------HTGEKPYE-------------------CNECGKFF 702

Query: 763 KHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAFAAKR 803
           +H  +L +H R H          CG+              H G KP+EC  C   F+ K 
Sbjct: 703 RHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKS 762

Query: 804 NCIHHILKQHLHVPE 818
           N I H   Q  H+ E
Sbjct: 763 NLIVH---QRRHIGE 774



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 90/382 (23%), Positives = 138/382 (36%), Gaps = 51/382 (13%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F   S L RH   HTGQKPF C +C+  F  KSN  +HQ    G         
Sbjct: 331  CNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGEKPFECNEC 390

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVL----DLTSRDREQPSEGATELRQVAGD 1363
            G    S +S +  H  T +        A G+      DLT   R        E  +    
Sbjct: 391  GKA-FSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTHTGLKPYECYECGKS 449

Query: 1364 APVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATK 1423
              V           H + H R  +H  E+     E  G +   + + + +Q + +     
Sbjct: 450  FRVTS---------HLKVHQR--THTGEKPFECLEC-GKSFSEKSNLTQHQRIHIG---- 493

Query: 1424 LMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGA 1483
                                 ++   C+ CGK+F     L+RH+  H   +P +    G 
Sbjct: 494  ---------------------DKSYECNACGKTFYHKSLLTRHQIIHTGWKPYECYECGK 532

Query: 1484 STAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLA-EETEGPSDGESAAEKRSSE 1542
            +   +      ++     +  A      P  G+  + K    +      GE   E     
Sbjct: 533  TFCLKSDLTVHQRTHTGQKPFA-----CPECGKFFSHKSTLSQHYRTHTGEKPYECHECG 587

Query: 1543 KSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCER 1602
            K   +K   T   K   +   ++   C+ C K F+    LT+H R H GE+PYKC  C +
Sbjct: 588  KIFYNKSYLT---KHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGK 644

Query: 1603 TFTLKHSLVRHQRIHQKARHAK 1624
             F  K +L+ HQR H + +  K
Sbjct: 645  AFCHKSALIVHQRTHTQEKPYK 666



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 97/391 (24%), Positives = 141/391 (36%), Gaps = 73/391 (18%)

Query: 1243 LQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTC 1302
            L+   C  C + F   S L+ H  THTG+KPF C +C   FS KSN  +HQ    G  + 
Sbjct: 438  LKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSY 497

Query: 1303 SLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAG 1362
                 G     K S +  H    +          G+   L S                  
Sbjct: 498  ECNACGKTFYHK-SLLTRHQIIHTGWKPYECYECGKTFCLKS------------------ 538

Query: 1363 DAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFAT 1422
            D  V Q T     P    E G+  SH+          TG+    E         +  + T
Sbjct: 539  DLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGEKP-YECHECGKIFYNKSYLT 597

Query: 1423 KLMDFKLAEGDGEAGAGGAA-------SQEQKL-------ACDTCGKSFKFLGTLSRHRK 1468
            K       E   E    G A       +Q Q++        C+ CGK+F     L  H++
Sbjct: 598  KHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQR 657

Query: 1469 AHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEG 1528
             H +++P      G S   +      E++                 GE P          
Sbjct: 658  THTQEKPYKCNECGKSFCVKSGLIFHERKH---------------TGEKP---------- 692

Query: 1529 PSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKK--VCSVCNKRFWSLQDLTRHM 1586
                         E ++  K  +  S  +V  +A   +K   C+ C K F+   +L +H 
Sbjct: 693  ------------YECNECGKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQ 740

Query: 1587 RSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            RSHTGE+PY+C TC +TF+ K +L+ HQR H
Sbjct: 741  RSHTGEKPYECNTCRKTFSQKSNLIVHQRRH 771



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 70/317 (22%), Positives = 121/317 (38%), Gaps = 36/317 (11%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q T   +  + C  C K  + +  LT H R H    G   + C+ CGK+    S L RH
Sbjct: 459 HQRTHTGEKPFECLECGKSFSEKSNLTQHQRIH---IGDKSYECNACGKTFYHKSLLTRH 515

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD-----PNSATATAPPSPLKR----- 165
            ++H+G +PY+C  CG++F    ++  H + H        P      +  S L +     
Sbjct: 516 QIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTH 575

Query: 166 -----------------RRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKK--ADE 206
                            +   +K   +H  E   E     K   +  Q    ++    ++
Sbjct: 576 TGEKPYECHECGKIFYNKSYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEK 635

Query: 207 VFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA 265
            + C  C K F  K  L  H  TH+ + P +C+ C  +F    GL+ H      + P + 
Sbjct: 636 PYKCNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYEC 695

Query: 266 --MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCE-TNLRRCISEQHRFVCDTCD 322
              G+ F   +          G     C +  +I     E    +R  + +  + C+TC 
Sbjct: 696 NECGKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCR 755

Query: 323 KAFPMLCSLALHKQTHV 339
           K F    +L +H++ H+
Sbjct: 756 KTFSQKSNLIVHQRRHI 772



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 49/168 (29%), Positives = 67/168 (39%), Gaps = 11/168 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R+H G  PYQCN C      K+ L +H RTH+G +PY C 
Sbjct: 385 FECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTHTGLKPYECY 444

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F V ++ + H R    +   + +E    +   S           D    C  CG+
Sbjct: 445 ECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYECNACGK 504

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
              H   L  H            H G KP+EC EC   F  K +   H
Sbjct: 505 TFYHKSLLTRHQII---------HTGWKPYECYECGKTFCLKSDLTVH 543



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 54/188 (28%), Positives = 74/188 (39%), Gaps = 22/188 (11%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H G  P+ C  C    + K+ L +H RTH+GE+PY C 
Sbjct: 525 YECYECGKTFCLKSDLTVHQRTHTGQKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECH 584

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F  K+   +H R    +   +  E    +   S           +    C  CG+
Sbjct: 585 ECGKIFYNKSYLTKHNRTHTGEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGK 644

Query: 761 DLKHYRALRIHMRTH----------CGRGL---------GGGHKGRKPFECKECSAAFAA 801
              H  AL +H RTH          CG+              H G KP+EC EC   F  
Sbjct: 645 AFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECNECGKFFRH 704

Query: 802 KRN-CIHH 808
           K +  +HH
Sbjct: 705 KSSLTVHH 712



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 70/294 (23%), Positives = 112/294 (38%), Gaps = 24/294 (8%)

Query: 91  DTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD 150
           D G     C+ CGK+    S L RH  VH+G++P++C  C ++F    N+ +H + H  +
Sbjct: 323 DKGEKHFECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSHTGE 382

Query: 151 PNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKAD----- 205
                     +   +  L+  ++ +H  E   +  A  K      Q  DL K        
Sbjct: 383 KPFECNECGKAFSHKSALTLHQR-THTGEKPYQCNACGKTFC---QKSDLTKHQRTHTGL 438

Query: 206 EVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNA--LVHKQLP 262
           + + C  C K F     L+ H  TH+ + P  C  C  +F     L +H    +  K   
Sbjct: 439 KPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYE 498

Query: 263 RDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWC----ETNLRRCISEQHRFVC 318
            +A G+ F   +          G+  + C +     + +C     T  +R  + Q  F C
Sbjct: 499 CNACGKTFYHKSLLTRHQIIHTGWKPYECYE---CGKTFCLKSDLTVHQRTHTGQKPFAC 555

Query: 319 DTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHT 372
             C K F    +L+ H +TH       EKP      G     K +L      HT
Sbjct: 556 PECGKFFSHKSTLSQHYRTHTG-----EKPYECHECGKIFYNKSYLTKHNRTHT 604



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 51/177 (28%), Positives = 68/177 (38%), Gaps = 38/177 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F    +L  H   H G  PY+C  C      K+ L  H RTH+G++P+ C 
Sbjct: 497 YECNACGKTFYHKSLLTRHQIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTGQKPFACP 556

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+ K+   +H R           EK  E                   C  CG+  
Sbjct: 557 ECGKFFSHKSTLSQHYR-------THTGEKPYE-------------------CHECGKIF 590

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQ 819
            +   L  H RT         H G KP+EC EC  AF  K     H   Q +H+ E+
Sbjct: 591 YNKSYLTKHNRT---------HTGEKPYECNECGKAFYQKSQLTQH---QRIHIGEK 635



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 51/178 (28%), Positives = 76/178 (42%), Gaps = 17/178 (9%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C+ CGK+F     L+RH++ H  Q+P  +  +      +       Q     E P
Sbjct: 326  EKHFECNECGKAFWEKSHLTRHQRVHTGQKP-FQCNECEKAFWDKSNLTKHQRSHTGEKP 384

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGE-----SAAEKRSSEKSDDDKKPKTDSPKSVA 1559
             E  E         A  L + T     GE     +A  K   +KSD  K  +T +     
Sbjct: 385  FECNECGKAFSHKSALTLHQRTH---TGEKPYQCNACGKTFCQKSDLTKHQRTHT----- 436

Query: 1560 SKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
                 +   C  C K F     L  H R+HTGE+P++C  C ++F+ K +L +HQRIH
Sbjct: 437  ---GLKPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIH 491



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 5/110 (4%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARHAKHH 1626
            C+ C K FW   +LT+H RSHTGE+P++C  C + F+ K +L  HQR H  +K       
Sbjct: 359  CNECEKAFWDKSNLTKHQRSHTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNAC 418

Query: 1627 GKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEG 1676
            GK   ++    + ++++ TH+G       E   +   ++H+ V +    G
Sbjct: 419  GKTFCQK---SDLTKHQRTHTGLKPYECYECGKSFRVTSHLKVHQRTHTG 465



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 28/59 (47%), Positives = 37/59 (62%), Gaps = 2/59 (3%)

Query: 1561 KADKRKK--VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            K DK +K   C+ C K FW    LTRH R HTG++P++C  CE+ F  K +L +HQR H
Sbjct: 321  KGDKGEKHFECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNLTKHQRSH 379



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 42/140 (30%), Positives = 57/140 (40%), Gaps = 2/140 (1%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F     L  H R+H    PY+CN C      K+ LI H R H+GE+PY C 
Sbjct: 637 YKCNECGKAFCHKSALIVHQRTHTQEKPYKCNECGKSFCVKSGLIFHERKHTGEKPYECN 696

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIE-KNIEYVSSSAAELVDAFCAPDTV-CRLCGE 760
            C   F  K++   H R    + + +  E   I Y  S  A+   +        C  C +
Sbjct: 697 ECGKFFRHKSSLTVHHRAHTGEKSCQCNECGKIFYRKSELAQHQRSHTGEKPYECNTCRK 756

Query: 761 DLKHYRALRIHMRTHCGRGL 780
                  L +H R H G  L
Sbjct: 757 TFSQKSNLIVHQRRHIGENL 776



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 68/330 (20%), Positives = 115/330 (34%), Gaps = 31/330 (9%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q +    + Y    CEK    +  L+   + H       D  C   G +      L   
Sbjct: 265 HQISPSRDNHYEFSDCEKFLCVKSTLS---KPHGVSMKHYD--CGESGNNFRRKLCLSHL 319

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLS 175
                GE+ ++C  CG++F    ++ RH ++H             +   +  L +K + S
Sbjct: 320 QKGDKGEKHFECNECGKAFWEKSHLTRHQRVHTGQKPFQCNECEKAFWDKSNL-TKHQRS 378

Query: 176 HDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHSD- 232
           H  E   E     K           ++    ++ + C  C K F  K  L  H  TH+  
Sbjct: 379 HTGEKPFECNECGKAFSHKSALTLHQRTHTGEKPYQCNACGKTFCQKSDLTKHQRTHTGL 438

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAM--GRPFIQNNPSIPAGFHDLGFTDFS 290
            P  C  C  +FR    L  H      + P + +  G+ F + +         +G   + 
Sbjct: 439 KPYECYECGKSFRVTSHLKVHQRTHTGEKPFECLECGKSFSEKSNLTQHQRIHIGDKSYE 498

Query: 291 CRKFPRISQAWCETNLRRCISEQHRFV--------CDTCDKAFPMLCSLALHKQTHVAAD 342
           C        A  +T   + +  +H+ +        C  C K F +   L +H++TH    
Sbjct: 499 C-------NACGKTFYHKSLLTRHQIIHTGWKPYECYECGKTFCLKSDLTVHQRTHTG-- 549

Query: 343 QGQEKPQATPLPGDALDQKGFLALLGLQHT 372
              +KP A P  G     K  L+     HT
Sbjct: 550 ---QKPFACPECGKFFSHKSTLSQHYRTHT 576



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 22/51 (43%), Positives = 28/51 (54%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHG 1298
            C  C ++F   S L +H  +HTG+KP+ C  C   FS KSN   HQ R  G
Sbjct: 723  CNECGKIFYRKSELAQHQRSHTGEKPYECNTCRKTFSQKSNLIVHQRRHIG 773



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/112 (25%), Positives = 41/112 (36%), Gaps = 5/112 (4%)

Query: 1182 EKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTN 1241
            +K  A  +  KF     T   + +      P + H     E G    +K    K N    
Sbjct: 550  QKPFACPECGKFFSHKSTLSQHYRTHTGEKPYECH-----ECGKIFYNKSYLTKHNRTHT 604

Query: 1242 CLQKITCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
              +   C  C + F   S L +H   H G+KP+ C +C   F  KS    HQ
Sbjct: 605  GEKPYECNECGKAFYQKSQLTQHQRIHIGEKPYKCNECGKAFCHKSALIVHQ 656



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 52/230 (22%), Positives = 83/230 (36%), Gaps = 53/230 (23%)

Query: 639 RKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           RK+   C  C   F     L     ++LG    + N C  +  +    I+H  TH+ E+ 
Sbjct: 136 RKMFCQCDSCGMSFNTVSELVISKINYLGKKSDEFNACGKLLLN----IKHDETHTQEKN 191

Query: 699 YICK----ICHYPFTVKAN-------------CERHLRKKHLKATRKDI---EKNIEY-- 736
            + K    + H+  T++               C+  L +K +  T+K     E N +Y  
Sbjct: 192 EVLKNRNTLSHHEETLQHEKIQTLEHNFEYSICQETLLEKAVFNTQKRENAEENNCDYNE 251

Query: 737 ---------------VSSSA------AELVDAFCAPDTVCRLCGEDLKHY---RALRIHM 772
                          +S S       ++     C   T+ +  G  +KHY    +     
Sbjct: 252 FGRTLCDSSSLLFHQISPSRDNHYEFSDCEKFLCVKSTLSKPHGVSMKHYDCGESGNNFR 311

Query: 773 RTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
           R  C   L  G KG K FEC EC  AF  K +   H   Q +H  ++  +
Sbjct: 312 RKLCLSHLQKGDKGEKHFECNECGKAFWEKSHLTRH---QRVHTGQKPFQ 358



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 63  KSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGE 122
           + S  C  C KI   + +L  H R H   TG   + C+ C K+ S  S+L  H   H GE
Sbjct: 718 EKSCQCNECGKIFYRKSELAQHQRSH---TGEKPYECNTCRKTFSQKSNLIVHQRRHIGE 774



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 15/49 (30%), Positives = 22/49 (44%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            C      F     L+   +   GE+ ++C  C + F  K  L RHQR+H
Sbjct: 303  CGESGNNFRRKLCLSHLQKGDKGEKHFECNECGKAFWEKSHLTRHQRVH 351


>gi|23308737 zinc finger protein 23 [Homo sapiens]
          Length = 643

 Score =  102 bits (255), Expect = 2e-21
 Identities = 78/305 (25%), Positives = 128/305 (41%), Gaps = 25/305 (8%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++QE   E+  Y C  C K  +   +L  H R H+   G     C  CGKS S +S    
Sbjct: 185 QHQENNTEEKPYQCSECGKAFSINEKLIWHQRLHS---GEKPFKCVECGKSFSYSSHYIT 241

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRK 173
           H  +HSGE+PY+C +CG++F+ NG++ RH +IH  + P                ++ +R 
Sbjct: 242 HQTIHSGEKPYQCKMCGKAFSVNGSLSRHQRIHTGEKPYQCKECGNGFSCSSAYITHQRV 301

Query: 174 LSHDAESEREDPAPA----KKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMET 229
            + +   E  D   A     K+++  +    EK     + C  C K F C   L  H   
Sbjct: 302 HTGEKPYECNDCGKAFNVNAKLIQHQRIHTGEKP----YECNECGKGFRCSSQLRQHQSI 357

Query: 230 HS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGF 286
           H+ + P +C  C   F  +  L++H  +   + P +    G+ F      I       G 
Sbjct: 358 HTGEKPYQCKECGKGFNNNTKLIQHQRIHTGEKPYECTECGKAFSVKGKLIQHQRIHTGE 417

Query: 287 TDFSCRKFPRISQAWCETNLR---RCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQ 343
             + C +  +  +  C +  R   R  + +  + C+ C KAF +   L  H++ H     
Sbjct: 418 KPYECNECGKAFR--CNSQFRQHLRIHTGEKPYECNECGKAFSVNGKLMRHQRIHTG--- 472

Query: 344 GQEKP 348
             EKP
Sbjct: 473 --EKP 475



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 82/318 (25%), Positives = 123/318 (38%), Gaps = 52/318 (16%)

Query: 34  GGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTG 93
           G  P   K   K    N    ++Q     +  Y C  C K  + + +L  H R H   TG
Sbjct: 360 GEKPYQCKECGKGFNNNTKLIQHQRIHTGEKPYECTECGKAFSVKGKLIQHQRIH---TG 416

Query: 94  GADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD-PN 152
              + C+ CGK+    S   +H+ +H+GE+PY+C  CG++F+ NG + RH +IH  + P 
Sbjct: 417 EKPYECNECGKAFRCNSQFRQHLRIHTGEKPYECNECGKAFSVNGKLMRHQRIHTGEKPF 476

Query: 153 SATATAPPSPLKRRRLSSKRKL-SHDAESEREDPAPAKKMVEDGQSGDLEKK-------- 203
                        R  +SKR L  H      E P   K   E G++  +  K        
Sbjct: 477 ECNECG-------RCFTSKRNLLDHHRIHTGEKPYQCK---ECGKAFSINAKLTRHQRIH 526

Query: 204 -ADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQL 261
             ++ F C  C K F C      H   H+ + P +C  C   F  +  L+RH        
Sbjct: 527 TGEKPFKCMECEKAFSCSSNYIVHQRIHTGEKPFQCKECGKAFHVNAHLIRHQ------- 579

Query: 262 PRDAMG-RPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDT 320
            R   G +PF      +  G    GF+  S     +    W           +  ++C  
Sbjct: 580 -RSHTGEKPF----RCVECG---KGFSFSSDYIIHQTVHTW-----------KKPYMCSV 620

Query: 321 CDKAFPMLCSLALHKQTH 338
           C KAF     L+ H+  H
Sbjct: 621 CGKAFRFSFQLSQHQSVH 638



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 60/199 (30%), Positives = 77/199 (38%), Gaps = 48/199 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C+ C + F+ +G L  H R H G  PYQC  C    +  +A I H R H+GE+PY C 
Sbjct: 252 YQCKMCGKAFSVNGSLSRHQRIHTGEKPYQCKECGNGFSCSSAYITHQRVHTGEKPYECN 311

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F V A   +H R   +    K  E                       C  CG+  
Sbjct: 312 DCGKAFNVNAKLIQHQR---IHTGEKPYE-----------------------CNECGKGF 345

Query: 763 KHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFAAKR 803
           +    LR H   H          CG+G             H G KP+EC EC  AF+ K 
Sbjct: 346 RCSSQLRQHQSIHTGEKPYQCKECGKGFNNNTKLIQHQRIHTGEKPYECTECGKAFSVKG 405

Query: 804 NCIHHILKQHLHVPEQDIE 822
             I H   Q +H  E+  E
Sbjct: 406 KLIQH---QRIHTGEKPYE 421



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 56/185 (30%), Positives = 70/185 (37%), Gaps = 45/185 (24%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S  LR H   H G  PYQC  C     +   LI+H R H+GE+PY C 
Sbjct: 336 YECNECGKGFRCSSQLRQHQSIHTGEKPYQCKECGKGFNNNTKLIQHQRIHTGEKPYECT 395

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+VK    +H R   +    K  E                       C  CG+  
Sbjct: 396 ECGKAFSVKGKLIQHQR---IHTGEKPYE-----------------------CNECGKAF 429

Query: 763 KHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFAAKR 803
           +     R H+R H          CG+              H G KPFEC EC   F +KR
Sbjct: 430 RCNSQFRQHLRIHTGEKPYECNECGKAFSVNGKLMRHQRIHTGEKPFECNECGRCFTSKR 489

Query: 804 NCIHH 808
           N + H
Sbjct: 490 NLLDH 494



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 58/185 (31%), Positives = 76/185 (41%), Gaps = 20/185 (10%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+  G L  H R H G  PY+CN C       +   +HLR H+GE+PY C 
Sbjct: 392 YECTECGKAFSVKGKLIQHQRIHTGEKPYECNECGKAFRCNSQFRQHLRIHTGEKPYECN 451

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKN-IEYVSSSAAELVDAF----CAPDTVCRL 757
            C   F+V     RH R   +    K  E N      +S   L+D            C+ 
Sbjct: 452 ECGKAFSVNGKLMRHQR---IHTGEKPFECNECGRCFTSKRNLLDHHRIHTGEKPYQCKE 508

Query: 758 CGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVP 817
           CG+       L  H R          H G KPF+C EC  AF+   N I H   Q +H  
Sbjct: 509 CGKAFSINAKLTRHQRI---------HTGEKPFKCMECEKAFSCSSNYIVH---QRIHTG 556

Query: 818 EQDIE 822
           E+  +
Sbjct: 557 EKPFQ 561



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 52/168 (30%), Positives = 72/168 (42%), Gaps = 11/168 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ +G L  H R H G  P++CN C      K  L+ H R H+GE+PY CK
Sbjct: 448 YECNECGKAFSVNGKLMRHQRIHTGEKPFECNECGRCFTSKRNLLDHHRIHTGEKPYQCK 507

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGE 760
            C   F++ A   RH R    +   K +E    +  SS   +       +    C+ CG+
Sbjct: 508 ECGKAFSINAKLTRHQRIHTGEKPFKCMECEKAFSCSSNYIVHQRIHTGEKPFQCKECGK 567

Query: 761 DLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHH 808
                  L  H R+         H G KPF C EC   F+   + I H
Sbjct: 568 AFHVNAHLIRHQRS---------HTGEKPFRCVECGKGFSFSSDYIIH 606



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 89/394 (22%), Positives = 136/394 (34%), Gaps = 37/394 (9%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F     L  H   H+G+KPF C +C   FS  S+   HQ    G      +  
Sbjct: 198  CSECGKAFSINEKLIWHQRLHSGEKPFKCVECGKSFSYSSHYITHQTIHSGEKPYQCKMC 257

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G    S    +  H    +          G     +S          T  R   G+ P E
Sbjct: 258  GKA-FSVNGSLSRHQRIHTGEKPYQCKECGNGFSCSSAY-------ITHQRVHTGEKPYE 309

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
                  A  V+ +       H  E+ +   E  G           +QS+     T    +
Sbjct: 310  CNDCGKAFNVNAKLIQHQRIHTGEKPYECNEC-GKGFRCSSQLRQHQSIH----TGEKPY 364

Query: 1428 KLAEGDGEAGAGGAASQEQKL-------ACDTCGKSFKFLGTLSRHRKAHGRQEPKD--E 1478
            +  E            Q Q++        C  CGK+F   G L +H++ H  ++P +  E
Sbjct: 365  QCKECGKGFNNNTKLIQHQRIHTGEKPYECTECGKAFSVKGKLIQHQRIHTGEKPYECNE 424

Query: 1479 KGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEK 1538
             G       +  Q       + P    E  ++    G+    +     E P +       
Sbjct: 425  CGKAFRCNSQFRQHLRIHTGEKPYECNECGKAFSVNGKLMRHQRIHTGEKPFECNECGRC 484

Query: 1539 RSSEKS--DDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYK 1596
             +S+++  D  +    + P             C  C K F     LTRH R HTGE+P+K
Sbjct: 485  FTSKRNLLDHHRIHTGEKPYQ-----------CKECGKAFSINAKLTRHQRIHTGEKPFK 533

Query: 1597 CQTCERTFTLKHSLVRHQRIH--QKARHAKHHGK 1628
            C  CE+ F+   + + HQRIH  +K    K  GK
Sbjct: 534  CMECEKAFSCSSNYIVHQRIHTGEKPFQCKECGK 567



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 59/202 (29%), Positives = 80/202 (39%), Gaps = 26/202 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ +  L  H R H G  P++C  C    +  +  I H   HSGE+PY CK
Sbjct: 196 YQCSECGKAFSINEKLIWHQRLHSGEKPFKCVECGKSFSYSSHYITHQTIHSGEKPYQCK 255

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSA---AELVDAFCAPDTVCRLCG 759
           +C   F+V  +  RH R    +   +  E    +  SSA    + V     P   C  CG
Sbjct: 256 MCGKAFSVNGSLSRHQRIHTGEKPYQCKECGNGFSCSSAYITHQRVHTGEKP-YECNDCG 314

Query: 760 EDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFA 800
           +       L  H R H          CG+G             H G KP++CKEC   F 
Sbjct: 315 KAFNVNAKLIQHQRIHTGEKPYECNECGKGFRCSSQLRQHQSIHTGEKPYQCKECGKGFN 374

Query: 801 AKRNCIHHILKQHLHVPEQDIE 822
                I H   Q +H  E+  E
Sbjct: 375 NNTKLIQH---QRIHTGEKPYE 393



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 59/227 (25%), Positives = 92/227 (40%), Gaps = 12/227 (5%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C+ CGK F+    L +H+  H  ++P   K  G        +    Q     E P
Sbjct: 333  EKPYECNECGKGFRCSSQLRQHQSIHTGEKPYQCKECGKGF-NNNTKLIQHQRIHTGEKP 391

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADK 1564
             E  E   G   +   KL +  +    GE   E     K+    +  +   + +     +
Sbjct: 392  YECTEC--GKAFSVKGKLIQH-QRIHTGEKPYECNECGKAF---RCNSQFRQHLRIHTGE 445

Query: 1565 RKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKARH 1622
            +   C+ C K F     L RH R HTGE+P++C  C R FT K +L+ H RIH  +K   
Sbjct: 446  KPYECNECGKAFSVNGKLMRHQRIHTGEKPFECNECGRCFTSKRNLLDHHRIHTGEKPYQ 505

Query: 1623 AKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAV 1669
             K  GK      +    + ++  H+G       E E A + S++  V
Sbjct: 506  CKECGKAFSINAK---LTRHQRIHTGEKPFKCMECEKAFSCSSNYIV 549



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 69/303 (22%), Positives = 115/303 (37%), Gaps = 36/303 (11%)

Query: 87  QHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKI 146
           Q +T TG     C+  GKS+S  + L +H +++S ERP+KC    + F  +  + +H + 
Sbjct: 130 QCHTITGEQPSGCTGLGKSISFDTKLVKHEIINSEERPFKCEELVEPFRCDSQLIQHQEN 189

Query: 147 H-EKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEK--- 202
           + E+ P   +       +  + +  +R   H  E          K VE G+S        
Sbjct: 190 NTEEKPYQCSECGKAFSINEKLIWHQR--LHSGEK-------PFKCVECGKSFSYSSHYI 240

Query: 203 ------KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNA 255
                   ++ + C +C K F     L  H   H+ + P +C  C   F      + H  
Sbjct: 241 THQTIHSGEKPYQCKMCGKAFSVNGSLSRHQRIHTGEKPYQCKECGNGFSCSSAYITHQR 300

Query: 256 LVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCIS-- 311
           +   + P +    G+ F  N   I       G   + C +  +  +  C + LR+  S  
Sbjct: 301 VHTGEKPYECNDCGKAFNVNAKLIQHQRIHTGEKPYECNECGKGFR--CSSQLRQHQSIH 358

Query: 312 -EQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQ 370
             +  + C  C K F     L  H++ H       EKP      G A   KG L    +Q
Sbjct: 359 TGEKPYQCKECGKGFNNNTKLIQHQRIHTG-----EKPYECTECGKAFSVKGKL----IQ 409

Query: 371 HTK 373
           H +
Sbjct: 410 HQR 412



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 46/180 (25%), Positives = 67/180 (37%), Gaps = 38/180 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C    + F     L  H  ++    PYQC+ C    +    LI H R HSGE+P+ C 
Sbjct: 168 FKCEELVEPFRCDSQLIQHQENNTEEKPYQCSECGKAFSINEKLIWHQRLHSGEKPFKCV 227

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+  ++   H        T    EK  +                   C++CG+  
Sbjct: 228 ECGKSFSYSSHYITH-------QTIHSGEKPYQ-------------------CKMCGKAF 261

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
               +L  H R H G          KP++CKEC   F+     I H   Q +H  E+  E
Sbjct: 262 SVNGSLSRHQRIHTGE---------KPYQCKECGNGFSCSSAYITH---QRVHTGEKPYE 309



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 78/374 (20%), Positives = 124/374 (33%), Gaps = 69/374 (18%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRN 1307
            C  C + F  +S L++H   HTG+KP+ C++C   F+  +   +HQ    G         
Sbjct: 338  CNECGKGFRCSSQLRQHQSIHTGEKPYQCKECGKGFNNNTKLIQHQRIHTGEKPYECTEC 397

Query: 1308 GLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVE 1367
            G     K   +  H    +          G+     S+ R+        LR   G+ P E
Sbjct: 398  GKAFSVKGKLI-QHQRIHTGEKPYECNECGKAFRCNSQFRQH-------LRIHTGEKPYE 449

Query: 1368 QATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDF 1427
                  A  V+      G+    +  H T E   + +      +S ++L       L   
Sbjct: 450  CNECGKAFSVN------GKLMRHQRIH-TGEKPFECNECGRCFTSKRNL-------LDHH 495

Query: 1428 KLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAE 1487
            ++  G            E+   C  CGK+F     L+RH++ H                 
Sbjct: 496  RIHTG------------EKPYQCKECGKAFSINAKLTRHQRIH---------------TG 528

Query: 1488 EGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDD 1547
            E P    E E+    +   +V      GE P +      E        A     ++S   
Sbjct: 529  EKPFKCMECEKAFSCSSNYIVHQRIHTGEKPFQC----KECGKAFHVNAHLIRHQRSHTG 584

Query: 1548 KKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLK 1607
            +KP                  C  C K F    D   H   HT ++PY C  C + F   
Sbjct: 585  EKPFR----------------CVECGKGFSFSSDYIIHQTVHTWKKPYMCSVCGKAFRFS 628

Query: 1608 HSLVRHQRIHQKAR 1621
              L +HQ +H + +
Sbjct: 629  FQLSQHQSVHSEGK 642



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  + C  C K       L  H R H   TG     C  CGK  S +S    H
Sbjct: 550 HQRIHTGEKPFQCKECGKAFHVNAHLIRHQRSH---TGEKPFRCVECGKGFSFSSDYIIH 606

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEK 149
             VH+ ++PY C+VCG++F  +  + +H  +H +
Sbjct: 607 QTVHTWKKPYMCSVCGKAFRFSFQLSQHQSVHSE 640



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 1560 SKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH-- 1617
            +  +++   CS C K F   + L  H R H+GE+P+KC  C ++F+     + HQ IH  
Sbjct: 189  NNTEEKPYQCSECGKAFSINEKLIWHQRLHSGEKPFKCVECGKSFSYSSHYITHQTIHSG 248

Query: 1618 QKARHAKHHGK 1628
            +K    K  GK
Sbjct: 249  EKPYQCKMCGK 259



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 21/75 (28%), Positives = 35/75 (46%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C+ C + F  +  L  H RSH G  P++C  C    +  +  I H   H+ ++PY+C 
Sbjct: 560 FQCKECGKAFHVNAHLIRHQRSHTGEKPFRCVECGKGFSFSSDYIIHQTVHTWKKPYMCS 619

Query: 703 ICHYPFTVKANCERH 717
           +C   F       +H
Sbjct: 620 VCGKAFRFSFQLSQH 634



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 17/56 (30%), Positives = 31/56 (55%)

Query: 1562 ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            +++R   C    + F     L +H  ++T E+PY+C  C + F++   L+ HQR+H
Sbjct: 163  SEERPFKCEELVEPFRCDSQLIQHQENNTEEKPYQCSECGKAFSINEKLIWHQRLH 218



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 58/274 (21%), Positives = 94/274 (34%), Gaps = 28/274 (10%)

Query: 89  NTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH- 147
           NT  G      S   +   S SS        +GE+P  CT  G+S + +  + +H  I+ 
Sbjct: 104 NTIDGTVKDETSPVEECFFSQSSNSYQCHTITGEQPSGCTGLGKSISFDTKLVKHEIINS 163

Query: 148 EKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKK---- 203
           E+ P        P           + + H   +  E P       E G++  + +K    
Sbjct: 164 EERPFKCEELVEPF------RCDSQLIQHQENNTEEKPYQCS---ECGKAFSINEKLIWH 214

Query: 204 -----ADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALV 257
                 ++ F C  C K F       TH   HS + P +C +C   F  +  L RH  + 
Sbjct: 215 QRLHSGEKPFKCVECGKSFSYSSHYITHQTIHSGEKPYQCKMCGKAFSVNGSLSRHQRIH 274

Query: 258 HKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCE-TNLRRCISEQH 314
             + P      G  F  ++  I       G   + C    +      +    +R  + + 
Sbjct: 275 TGEKPYQCKECGNGFSCSSAYITHQRVHTGEKPYECNDCGKAFNVNAKLIQHQRIHTGEK 334

Query: 315 RFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            + C+ C K F     L  H+  H       EKP
Sbjct: 335 PYECNECGKGFRCSSQLRQHQSIHTG-----EKP 363


>gi|52138523 zinc finger protein 418 [Homo sapiens]
          Length = 676

 Score =  102 bits (255), Expect = 2e-21
 Identities = 87/334 (26%), Positives = 131/334 (39%), Gaps = 18/334 (5%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     K  Y C  C K  + +  L  H R H   TG   + C  CGKS S   SL +H
Sbjct: 248 HQRVHTGKRPYECGECGKSFSHKGSLVQHQRVH---TGKRPYECGECGKSFSHKGSLVQH 304

Query: 116 MLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKD-PNSATATAPPSPLKRRRLSSKRKL 174
             VH+GERPY+C  CG+SF+ NG + +H ++H  + P            K   +  +R  
Sbjct: 305 QRVHTGERPYECGECGKSFSQNGTLIKHQRVHTGERPYECEECGKCFTQKGNLIQHQR-- 362

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHS- 231
            H +E   E     K   + G   +  +    +  + C  C K F  K  L  H   H+ 
Sbjct: 363 GHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTG 422

Query: 232 DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMG--RPFIQNNPSIPAGFHDLGFTDF 289
           + P  C  C  +F     L++H      + P +     + F   +  I       G   +
Sbjct: 423 ERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVHTGERPY 482

Query: 290 SCRKFPRISQAWCETNL-RRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C +  +  Q      + +R  + +  F C  C K+FP  CSL  H++ H       E+P
Sbjct: 483 ECNECGKSFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHTG-----ERP 537

Query: 349 QATPLPGDALDQKGFLALLGLQHTKDVRPAPAEE 382
                 G +  Q   L      HT + RP    E
Sbjct: 538 YECGECGKSFHQSSSLLRHQKTHTAE-RPYECRE 570



 Score =  100 bits (249), Expect = 1e-20
 Identities = 78/295 (26%), Positives = 120/295 (40%), Gaps = 16/295 (5%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++Q     K  Y C  C K  + +  L  H R H   TG   + C  CGKS S   +L +
Sbjct: 275 QHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVH---TGERPYECGECGKSFSQNGTLIK 331

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKL 174
           H  VH+GERPY+C  CG+ FT  GN+ +H + H  +             ++  L+   ++
Sbjct: 332 HQRVHTGERPYECEECGKCFTQKGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRV 391

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETHS- 231
            H  E   E     K     G   + ++    +  + C  C K F  K  L  H  +H+ 
Sbjct: 392 -HTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTG 450

Query: 232 DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDF 289
           + P  C  C   FR    L+ H  +   + P +    G+ F  ++          G   F
Sbjct: 451 ERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEKPF 510

Query: 290 SC----RKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVA 340
            C    + FP   Q+      RR  + +  + C  C K+F    SL  H++TH A
Sbjct: 511 ECSECGKSFP---QSCSLLRHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTA 562



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 72/291 (24%), Positives = 117/291 (40%), Gaps = 15/291 (5%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++Q     +  Y C  C K  T +  L  H R H   T    + C  CGK  S   +L  
Sbjct: 331 KHQRVHTGERPYECEECGKCFTQKGNLIQHQRGH---TSERPYECEECGKCFSQKGTLTE 387

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKL 174
           H  VH+ ERPY+C  CG+SF+  G++  H + H  +          S  ++  L   ++ 
Sbjct: 388 HHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQR- 446

Query: 175 SHDAESEREDPAPAKKMVEDGQSGDLEKK----ADEVFHCPVCFKEFVCKYGLETHMETH 230
           SH  E   E     +K+   G+S  +E +     +  + C  C K F    G   H   H
Sbjct: 447 SHTGERPYE-CRECRKLFR-GKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVH 504

Query: 231 S-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFT 287
           + + P  C  C  +F     LLRH  +   + P +    G+ F Q++  +          
Sbjct: 505 TGEKPFECSECGKSFPQSCSLLRHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAER 564

Query: 288 DFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
            + CR+  +   +  E   RR  + +  + C  C K F    +   H++ H
Sbjct: 565 PYECRECGKFFSSLLEH--RRVHTGERPYECRECGKTFTRRSAHFKHQRLH 613



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 60/184 (32%), Positives = 79/184 (42%), Gaps = 18/184 (9%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+  G L  H R H G  PY+C  C    +    LI+H R H+GERPY C+
Sbjct: 286 YECGECGKSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVHTGERPYECE 345

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAA----ELVDAFCAPDTVCRLC 758
            C   FT K N  +H ++ H      + E+  +  S          V     P   C  C
Sbjct: 346 ECGKCFTQKGNLIQH-QRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERP-YECGEC 403

Query: 759 GEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPE 818
           G+       LR H R         GH G +P+EC EC  +F+ K N I H   Q  H  E
Sbjct: 404 GKSFSRKGHLRNHQR---------GHTGERPYECGECGKSFSRKGNLIQH---QRSHTGE 451

Query: 819 QDIE 822
           +  E
Sbjct: 452 RPYE 455



 Score = 88.2 bits (217), Expect = 6e-17
 Identities = 76/296 (25%), Positives = 117/296 (39%), Gaps = 25/296 (8%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++Q     +  Y C  C K  + +  LT H R H  +     + C  CGKS S    L  
Sbjct: 359 QHQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRER---PYECGECGKSFSRKGHLRN 415

Query: 115 HMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKL 174
           H   H+GERPY+C  CG+SF+  GN+ +H + H       T   P    + R+L   R  
Sbjct: 416 HQRGHTGERPYECGECGKSFSRKGNLIQHQRSH-------TGERPYECRECRKLF--RGK 466

Query: 175 SHDAESER----EDPAPAK---KMVEDGQSGDLEKKA---DEVFHCPVCFKEFVCKYGLE 224
           SH  E +R    E P       K  +D     + ++    ++ F C  C K F     L 
Sbjct: 467 SHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLL 526

Query: 225 THMETHS-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHD 283
            H   H+ + P  C  C  +F     LLRH      + P +        ++       H 
Sbjct: 527 RHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSSLLEHRRVHT 586

Query: 284 LGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
            G   + CR+  +  ++       +R  +    + C  C K+F    SL  H++ H
Sbjct: 587 -GERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVH 641



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 95/411 (23%), Positives = 135/411 (32%), Gaps = 70/411 (17%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTT------ 1301
            C  C + F    SL +H   HTG++P+ C +C   FS      +HQ    G         
Sbjct: 288  CGECGKSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVHTGERPYECEEC 347

Query: 1302 --CSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQ 1359
              C  ++  LI   +      H S       E      +   LT   R    E   E  +
Sbjct: 348  GKCFTQKGNLIQHQR-----GHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGE 402

Query: 1360 VAGDAPVEQATAETASPVHREEHGRGESHEPEEEHG----TEESTGDADGAEEDASSNQS 1415
                          +   H   H RG + E   E G    +    G+    +   +  + 
Sbjct: 403  CG---------KSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERP 453

Query: 1416 LDLDFATKLMDFK----------LAEGDGEAGAGGAASQ--------------EQKLACD 1451
             +     KL   K            E   E    G + Q              E+   C 
Sbjct: 454  YECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEKPFECS 513

Query: 1452 TCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESA 1511
             CGKSF    +L RHR+ H  + P  E G+   +  +       Q+    E P E  E  
Sbjct: 514  ECGKSFPQSCSLLRHRRVHTGERPY-ECGECGKSFHQSSSLLRHQKTHTAERPYECRECG 572

Query: 1512 PGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADK-----RK 1566
                     +     E P +                   KT + +S   K  +     + 
Sbjct: 573  KFFSSLLEHRRVHTGERPYECRECG--------------KTFTRRSAHFKHQRLHTRGKP 618

Query: 1567 KVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
              CS C K F     LT H R HTGERPY+C  C ++F    SL+RHQR+H
Sbjct: 619  YECSECGKSFAETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVH 669



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 53/180 (29%), Positives = 74/180 (41%), Gaps = 38/180 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+  G LR H R H G  PY+C  C    + K  LI+H R+H+GERPY C+
Sbjct: 398 YECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECR 457

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F  K++   H R   +    +  E                       C  CG+  
Sbjct: 458 ECRKLFRGKSHLIEHQR---VHTGERPYE-----------------------CNECGKSF 491

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
           +     R+H R          H G KPFEC EC  +F    + + H   + +H  E+  E
Sbjct: 492 QDSSGFRVHQRV---------HTGEKPFECSECGKSFPQSCSLLRH---RRVHTGERPYE 539



 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 51/185 (27%), Positives = 76/185 (41%), Gaps = 20/185 (10%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F  S   R H R H G  P++C+ C        +L+RH R H+GERPY C 
Sbjct: 482 YECNECGKSFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHTGERPYECG 541

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F   ++  RH +K H      +  +  ++ SS               CR CG+  
Sbjct: 542 ECGKSFHQSSSLLRH-QKTHTAERPYECRECGKFFSSLLEHRRVHTGERPYECRECGKTF 600

Query: 763 K----HYRALRIHMR------THCGRGLGGG---------HKGRKPFECKECSAAFAAKR 803
                H++  R+H R      + CG+              H G +P+EC EC  +F    
Sbjct: 601 TRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVHTGERPYECSECGKSFHRSS 660

Query: 804 NCIHH 808
           + + H
Sbjct: 661 SLLRH 665



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 71/289 (24%), Positives = 104/289 (35%), Gaps = 37/289 (12%)

Query: 54  RRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLD 113
           R +Q     +  Y C  C K  + +  L  H R H   TG   + C  C K     S L 
Sbjct: 414 RNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSH---TGERPYECRECRKLFRGKSHLI 470

Query: 114 RHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKR 172
            H  VH+GERPY+C  CG+SF  +     H ++H  + P   +      P     L  +R
Sbjct: 471 EHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRR 530

Query: 173 KLSHDAESEREDPAPAKKMVEDGQSGDLEK--KADEVFHCPVCFKEFVCKYGLETHMETH 230
              H  E   E     K   +       +K   A+  + C  C K F     L  H   H
Sbjct: 531 --VHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFF---SSLLEHRRVH 585

Query: 231 S-DNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDF 289
           + + P  C  C  TF       +H  L          G+P+  +                
Sbjct: 586 TGERPYECRECGKTFTRRSAHFKHQRL-------HTRGKPYECS---------------- 622

Query: 290 SCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
            C K    ++ +  T  RR  + +  + C  C K+F    SL  H++ H
Sbjct: 623 ECGK--SFAETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVH 669



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 90/385 (23%), Positives = 141/385 (36%), Gaps = 38/385 (9%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQL-----RKHGVTTC 1302
            C  C + F    SL +H   HTG++P+ C +C   FS K +  +HQ      R +    C
Sbjct: 260  CGECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYECGEC 319

Query: 1303 --SLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQV 1360
              S  +NG + + +    G           E      +  +L    R   SE   E  + 
Sbjct: 320  GKSFSQNGTLIKHQRVHTGERP----YECEECGKCFTQKGNLIQHQRGHTSERPYECEE- 374

Query: 1361 AGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDF 1420
             G    ++ T       H   H R   +E  E   +    G     +   +  +  +   
Sbjct: 375  CGKCFSQKGTLTE----HHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGE 430

Query: 1421 ATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKG 1480
              K    K      +    G    E+   C  C K F+    L  H++ H  + P +   
Sbjct: 431  CGKSFSRKGNLIQHQRSHTG----ERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNE 486

Query: 1481 DGASTAEEGPQPAPEQE---EKPPETPAEVVESAPGAGEAPAEKLAEETEGPSD-GESAA 1536
             G S  +       ++    EKP E  +E  +S P +      +     E P + GE   
Sbjct: 487  CGKSFQDSSGFRVHQRVHTGEKPFEC-SECGKSFPQSCSLLRHRRVHTGERPYECGECGK 545

Query: 1537 EKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYK 1596
                S      +K  T           +R   C  C K F SL +   H R HTGERPY+
Sbjct: 546  SFHQSSSLLRHQKTHTA----------ERPYECRECGKFFSSLLE---HRRVHTGERPYE 592

Query: 1597 CQTCERTFTLKHSLVRHQRIHQKAR 1621
            C+ C +TFT + +  +HQR+H + +
Sbjct: 593  CRECGKTFTRRSAHFKHQRLHTRGK 617



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 70/283 (24%), Positives = 111/283 (39%), Gaps = 19/283 (6%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y+C  C K  +T+H      R  + +    +  C  CGKS S   S+  H  VH+G+RPY
Sbjct: 203 YSCGECMKHSSTKHVFVQQQRLPSRE----ECYCWECGKSFSKYDSVSNHQRVHTGKRPY 258

Query: 126 KCTVCGQSFTTNGNMHRHMKIHE-KDPNSATATAPPSPLKRRRLSSKRKLSHDAESERED 184
           +C  CG+SF+  G++ +H ++H  K P            K   +  +R   H  E   E 
Sbjct: 259 ECGECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQR--VHTGERPYEC 316

Query: 185 PAPAKKMVEDGQSGDLEK-----KADEVFHCPVCFKEFVCKYGLETHMETH-SDNPLRCD 238
               K      Q+G L K       +  + C  C K F  K  L  H   H S+ P  C+
Sbjct: 317 GECGKSF---SQNGTLIKHQRVHTGERPYECEECGKCFTQKGNLIQHQRGHTSERPYECE 373

Query: 239 ICCVTFRTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR 296
            C   F     L  H+ +  ++ P +    G+ F +            G   + C +  +
Sbjct: 374 ECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGK 433

Query: 297 -ISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
             S+       +R  + +  + C  C K F     L  H++ H
Sbjct: 434 SFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVH 476



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 61/210 (29%), Positives = 90/210 (42%), Gaps = 14/210 (6%)

Query: 1450 CDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVE 1509
            C  CGKSF   G+L +H++ H  + P +    G S ++ G      Q     E P E  E
Sbjct: 288  CGECGKSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTL-IKHQRVHTGERPYECEE 346

Query: 1510 SAPGAGEAPAEK--LAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKK 1567
                 G+   +K  L +   G +  E   E     K    K   T+  +       +R  
Sbjct: 347  ----CGKCFTQKGNLIQHQRGHTS-ERPYECEECGKCFSQKGTLTEHHRV---HTRERPY 398

Query: 1568 VCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHG 1627
             C  C K F     L  H R HTGERPY+C  C ++F+ K +L++HQR H   R   +  
Sbjct: 399  ECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGER--PYEC 456

Query: 1628 KDSDKEERGEED-SENESTHSGNNAVSENE 1656
            ++  K  RG+    E++  H+G      NE
Sbjct: 457  RECRKLFRGKSHLIEHQRVHTGERPYECNE 486



 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 49/180 (27%), Positives = 68/180 (37%), Gaps = 38/180 (21%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+  G L  H R H G  PY+C  C    + K +L++H R H+GERPY C 
Sbjct: 258 YECGECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYECG 317

Query: 703 ICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDL 762
            C   F+      +H R   +    +  E                       C  CG+  
Sbjct: 318 ECGKSFSQNGTLIKHQR---VHTGERPYE-----------------------CEECGKCF 351

Query: 763 KHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
                L  H R         GH   +P+EC+EC   F+ K     H     +H  E+  E
Sbjct: 352 TQKGNLIQHQR---------GHTSERPYECEECGKCFSQKGTLTEH---HRVHTRERPYE 399



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 38/178 (21%)

Query: 645 CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKIC 704
           C  C + F+    +  H R H G  PY+C  C    + K +L++H R H+G+RPY C  C
Sbjct: 232 CWECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGKRPYECGEC 291

Query: 705 HYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKH 764
              F+ K +  +H R   +    +  E                       C  CG+    
Sbjct: 292 GKSFSHKGSLVQHQR---VHTGERPYE-----------------------CGECGKSFSQ 325

Query: 765 YRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIE 822
              L  H R H G          +P+EC+EC   F  K N I H   Q  H  E+  E
Sbjct: 326 NGTLIKHQRVHTGE---------RPYECEECGKCFTQKGNLIQH---QRGHTSERPYE 371



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 36/87 (41%), Positives = 49/87 (56%), Gaps = 4/87 (4%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  C K  T +     H R H   T G  + CS CGKS +   SL  H  VH+GERPY
Sbjct: 591 YECRECGKTFTRRSAHFKHQRLH---TRGKPYECSECGKSFAETFSLTEHRRVHTGERPY 647

Query: 126 KCTVCGQSFTTNGNMHRHMKIH-EKDP 151
           +C+ CG+SF  + ++ RH ++H E+ P
Sbjct: 648 ECSECGKSFHRSSSLLRHQRVHTERSP 674



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 87/383 (22%), Positives = 132/383 (34%), Gaps = 59/383 (15%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKH--------GV 1299
            C  C + F    S+  H   HTG++P+ C +C   FS K +  +HQ R H        G 
Sbjct: 232  CWECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQ-RVHTGKRPYECGE 290

Query: 1300 TTCSLRRNGLIPQSKESDVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQ 1359
               S    G + Q +    G           E   +  +   L    R    E   E  +
Sbjct: 291  CGKSFSHKGSLVQHQRVHTGER----PYECGECGKSFSQNGTLIKHQRVHTGERPYECEE 346

Query: 1360 VAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLD 1419
                   +  T +     H+  H     +E EE        G         +  +  +  
Sbjct: 347  CG-----KCFTQKGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECG 401

Query: 1420 FATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEK 1479
               K    K    + + G  G    E+   C  CGKSF   G L +H+++H  + P + +
Sbjct: 402  ECGKSFSRKGHLRNHQRGHTG----ERPYECGECGKSFSRKGNLIQHQRSHTGERPYECR 457

Query: 1480 GDGASTAEEGPQPAPEQEEKPPETPAEVVE-SAPGAGEAPAEKLAEETEGPSDGESAAEK 1538
                            +  K     + ++E      GE P E      E     + ++  
Sbjct: 458  ----------------ECRKLFRGKSHLIEHQRVHTGERPYEC----NECGKSFQDSSGF 497

Query: 1539 RSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQ 1598
            R  ++    +KP                  CS C K F     L RH R HTGERPY+C 
Sbjct: 498  RVHQRVHTGEKPFE----------------CSECGKSFPQSCSLLRHRRVHTGERPYECG 541

Query: 1599 TCERTFTLKHSLVRHQRIHQKAR 1621
             C ++F    SL+RHQ+ H   R
Sbjct: 542  ECGKSFHQSSSLLRHQKTHTAER 564



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 58/246 (23%), Positives = 101/246 (41%), Gaps = 44/246 (17%)

Query: 1407 EEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRH 1466
            +E+A S +S+ +   +++           +  G   S ++  +C+ CG     +  L+ H
Sbjct: 52   DEEAPSKKSISIQRVSQV-----------STPGAGVSPKKAHSCEMCGAILGDILHLADH 100

Query: 1467 RKAHGRQEPKDEKGDGASTAEEGPQPAPEQ--EEKPPETPAEVVESAPGAGEAPAEKLAE 1524
            +  H +Q+    +  G    +   +P   Q   EKP  +  E            +E+ + 
Sbjct: 101  QGTHHKQKLHRCEAWGNKLYDSSNRPHQNQYLGEKPYRSSVEEALFVKRCKFHVSEESSI 160

Query: 1525 ETEG-----PSDGESAAE-KRSSEKSDDDKKPKTDSP--------------KSVASK--- 1561
              +      PS G    E   + EKS  + KP+ +SP              K  ++K   
Sbjct: 161  FIQSGKDFLPSSGLLLQEATHTGEKS--NSKPECESPFQWGDTHYSCGECMKHSSTKHVF 218

Query: 1562 ------ADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQR 1615
                    + +  C  C K F     ++ H R HTG+RPY+C  C ++F+ K SLV+HQR
Sbjct: 219  VQQQRLPSREECYCWECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQR 278

Query: 1616 IHQKAR 1621
            +H   R
Sbjct: 279  VHTGKR 284



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 28/77 (36%), Positives = 36/77 (46%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y CR C + F        H R H    PY+C+ C    A+  +L  H R H+GERPY C 
Sbjct: 591 YECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVHTGERPYECS 650

Query: 703 ICHYPFTVKANCERHLR 719
            C   F   ++  RH R
Sbjct: 651 ECGKSFHRSSSLLRHQR 667



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 28/72 (38%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 55  RNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDR 114
           ++Q        Y C  C K       LT H R H   TG   + CS CGKS   +SSL R
Sbjct: 608 KHQRLHTRGKPYECSECGKSFAETFSLTEHRRVH---TGERPYECSECGKSFHRSSSLLR 664

Query: 115 HMLVHSGERPYK 126
           H  VH+   PYK
Sbjct: 665 HQRVHTERSPYK 676



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 61/301 (20%), Positives = 104/301 (34%), Gaps = 23/301 (7%)

Query: 97  HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNM-HRHMKIHEKDPNSAT 155
           HSC +CG  L     L  H   H  ++ ++C   G     + N  H++  + EK   S+ 
Sbjct: 82  HSCEMCGAILGDILHLADHQGTHHKQKLHRCEAWGNKLYDSSNRPHQNQYLGEKPYRSSV 141

Query: 156 ATAPPSPLKRRRLSSKRKLSHDAESERED-PAPAKKMVEDGQSGDLEKK----------A 204
             A    +KR +     + S   +S ++  P+    + E   +G+               
Sbjct: 142 EEA--LFVKRCKFHVSEESSIFIQSGKDFLPSSGLLLQEATHTGEKSNSKPECESPFQWG 199

Query: 205 DEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRD 264
           D  + C  C K    K+         S     C  C  +F  +  +  H  +   + P +
Sbjct: 200 DTHYSCGECMKHSSTKHVFVQQQRLPSREECYCWECGKSFSKYDSVSNHQRVHTGKRPYE 259

Query: 265 A--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAWCETNLRRCISEQHRFVCDTC 321
               G+ F      +       G   + C +  +  S        +R  + +  + C  C
Sbjct: 260 CGECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYECGEC 319

Query: 322 DKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAE 381
            K+F    +L  H++ H       E+P      G    QKG L      HT + RP   E
Sbjct: 320 GKSFSQNGTLIKHQRVHTG-----ERPYECEECGKCFTQKGNLIQHQRGHTSE-RPYECE 373

Query: 382 E 382
           E
Sbjct: 374 E 374



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 21/57 (36%), Positives = 29/57 (50%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPY 699
           Y C  C + FA +  L  H R H G  PY+C+ C       ++L+RH R H+   PY
Sbjct: 619 YECSECGKSFAETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVHTERSPY 675


>gi|116875834 zinc finger protein 74 [Homo sapiens]
          Length = 644

 Score =  102 bits (255), Expect = 2e-21
 Identities = 74/277 (26%), Positives = 116/277 (41%), Gaps = 34/277 (12%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           Y C  CEK  +    L+MH+R H   TG   + C  CGK+ +  + L RH  +H+GE+PY
Sbjct: 332 YKCSACEKAFSCSSLLSMHLRVH---TGEKPYRCGECGKAFNQRTHLTRHHRIHTGEKPY 388

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDP 185
           +C  CG++FT + ++  H KIH  D     +    +   R RL+  ++ +H  E      
Sbjct: 389 QCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSDCEKAFNSRSRLTLHQR-THTGE------ 441

Query: 186 APAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTF 244
                               + F C  C K F C   L  H   HS + P +C+ C   F
Sbjct: 442 --------------------KPFKCADCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKAF 481

Query: 245 RTHRGLLRHNALVHKQLPRDA--MGRPFIQNNPSIPAGFHDLGFTDFSCRKFPR-ISQAW 301
            +H  L+ H  +   + P D     + F  ++  I       G   + C +  R  SQ  
Sbjct: 482 SSHAYLIVHRRIHTGEKPFDCSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQNH 541

Query: 302 CETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTH 338
           C    ++  S +  F C+ C + F     L  H++ H
Sbjct: 542 CLIKHQKIHSGEKSFKCEKCGEMFNWSSHLTEHQRLH 578



 Score = 84.7 bits (208), Expect = 7e-16
 Identities = 82/345 (23%), Positives = 129/345 (37%), Gaps = 44/345 (12%)

Query: 10  EGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCP 69
           EG  L      + A     K      + +   +PS+P    ++ RR +     +  + C 
Sbjct: 193 EGGPLLDTRKNVQATEGRTKAPARLCAGENASTPSEPEKFPQV-RRQRGAGAGEGEFVCG 251

Query: 70  LCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTV 129
            C K       LT+H R H+ +     + C  CGK+ + +++L  H  +H+GE+P+ C  
Sbjct: 252 ECGKAFRQSSSLTLHRRWHSREKA---YKCDECGKAFTWSTNLLEHRRIHTGEKPFFCGE 308

Query: 130 CGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAK 189
           CG++F+ + +++ H +IH  +      +A         L S     H  E         K
Sbjct: 309 CGKAFSCHSSLNVHQRIHTGE-RPYKCSACEKAFSCSSLLSMHLRVHTGEKPYRCGECGK 367

Query: 190 KMVEDGQSGDLEK-----KADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVT 243
                 Q   L +       ++ + C  C K F C   L  H + HS D P +C  C   
Sbjct: 368 AF---NQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSDCEKA 424

Query: 244 FRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCE 303
           F +   L  H         R   G          P    D G   FSC  +  +      
Sbjct: 425 FNSRSRLTLHQ--------RTHTGEK--------PFKCADCG-KGFSCHAYLLVH----- 462

Query: 304 TNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
              RR  S +  F C+ C KAF     L +H++ H       EKP
Sbjct: 463 ---RRIHSGEKPFKCNECGKAFSSHAYLIVHRRIHTG-----EKP 499



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 57/200 (28%), Positives = 79/200 (39%), Gaps = 28/200 (14%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           Y C  C + F+ S +L  H+R H G  PY+C  C      +  L RH R H+GE+PY C 
Sbjct: 332 YKCSACEKAFSCSSLLSMHLRVHTGEKPYRCGECGKAFNQRTHLTRHHRIHTGEKPYQCG 391

Query: 703 ICHYPFTVKANCERHLR----KKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLC 758
            C   FT  ++   H +     K  K +  D EK     S                C  C
Sbjct: 392 SCGKAFTCHSSLTVHEKIHSGDKPFKCS--DCEKAFNSRSRLTLHQRTHTGEKPFKCADC 449

Query: 759 GEDLKHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAF 799
           G+    +  L +H R H          CG+              H G KPF+C +C  AF
Sbjct: 450 GKGFSCHAYLLVHRRIHSGEKPFKCNECGKAFSSHAYLIVHRRIHTGEKPFDCSQCWKAF 509

Query: 800 AAKRNCIHHILKQHLHVPEQ 819
           +   + I H   Q +H  E+
Sbjct: 510 SCHSSLIVH---QRIHTGEK 526



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 53/199 (26%), Positives = 81/199 (40%), Gaps = 24/199 (12%)

Query: 645 CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKIC 704
           C  C + F+    L  H R H G  PY+C+ C+   +  + L  HLR H+GE+PY C  C
Sbjct: 306 CGECGKAFSCHSSLNVHQRIHTGERPYKCSACEKAFSCSSLLSMHLRVHTGEKPYRCGEC 365

Query: 705 HYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDT--VCRLCGEDL 762
              F  + +  RH R    +   +       +   S+  + +   + D    C  C +  
Sbjct: 366 GKAFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSDCEKAF 425

Query: 763 KHYRALRIHMRTH----------CGRGLGGG---------HKGRKPFECKECSAAFAAKR 803
                L +H RTH          CG+G             H G KPF+C EC  AF++  
Sbjct: 426 NSRSRLTLHQRTHTGEKPFKCADCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKAFSSHA 485

Query: 804 NCIHHILKQHLHVPEQDIE 822
             I H   + +H  E+  +
Sbjct: 486 YLIVH---RRIHTGEKPFD 501



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 52/182 (28%), Positives = 77/182 (42%), Gaps = 15/182 (8%)

Query: 1440 GAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPK--DEKGDGASTAEEGPQPAPEQE 1497
            GA + E +  C  CGK+F+   +L+ HR+ H R++    DE G   + +    +      
Sbjct: 240  GAGAGEGEFVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHT 299

Query: 1498 EKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKS 1557
             + P    E  ++          +     E P    SA EK  S            S  S
Sbjct: 300  GEKPFFCGECGKAFSCHSSLNVHQRIHTGERPYKC-SACEKAFS----------CSSLLS 348

Query: 1558 VASKADKRKKV--CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQR 1615
            +  +    +K   C  C K F     LTRH R HTGE+PY+C +C + FT   SL  H++
Sbjct: 349  MHLRVHTGEKPYRCGECGKAFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEK 408

Query: 1616 IH 1617
            IH
Sbjct: 409  IH 410



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125
           ++C  C K  +    L +H R H   TG   + CS CG++ S    L +H  +HSGE+ +
Sbjct: 500 FDCSQCWKAFSCHSSLIVHQRIH---TGEKPYKCSECGRAFSQNHCLIKHQKIHSGEKSF 556

Query: 126 KCTVCGQSFTTNGNMHRHMKIHEK 149
           KC  CG+ F  + ++  H ++H +
Sbjct: 557 KCEKCGEMFNWSSHLTEHQRLHSE 580



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 26/56 (46%), Positives = 32/56 (57%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAK 1624
            CS C K F     L  H R HTGE+PYKC  C R F+  H L++HQ+IH   +  K
Sbjct: 502  CSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQNHCLIKHQKIHSGEKSFK 557



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 51/198 (25%), Positives = 70/198 (35%), Gaps = 24/198 (12%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F  S  L  H R H     Y+C+ C         L+ H R H+GE+P+ C 
Sbjct: 248 FVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTGEKPFFCG 307

Query: 703 ICHYPFTVKANCERHLRKKHLKATRK--DIEKNIEYVSSSAAELVDAFCAPDTVCRLCGE 760
            C   F+  ++   H R    +   K    EK     S  +  L          C  CG+
Sbjct: 308 ECGKAFSCHSSLNVHQRIHTGERPYKCSACEKAFSCSSLLSMHLRVHTGEKPYRCGECGK 367

Query: 761 DLKHYRALRIHMRTHCGR-----GLGGG--------------HKGRKPFECKECSAAFAA 801
                  L  H R H G      G  G               H G KPF+C +C  AF +
Sbjct: 368 AFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSDCEKAFNS 427

Query: 802 KRNCIHHILKQHLHVPEQ 819
           +     H   Q  H  E+
Sbjct: 428 RSRLTLH---QRTHTGEK 442



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 1564 KRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH--QKAR 1621
            +R   CS C K F     L+ H+R HTGE+PY+C  C + F  +  L RH RIH  +K  
Sbjct: 329  ERPYKCSACEKAFSCSSLLSMHLRVHTGEKPYRCGECGKAFNQRTHLTRHHRIHTGEKPY 388

Query: 1622 HAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEG 1676
                 GK           + +E  HSG+     ++ E A N+ + + + +    G
Sbjct: 389  QCGSCGKAFTCH---SSLTVHEKIHSGDKPFKCSDCEKAFNSRSRLTLHQRTHTG 440



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 44/149 (29%), Positives = 62/149 (41%), Gaps = 25/149 (16%)

Query: 1480 GDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAA--- 1536
            G+ AST        P + EK P+     V    GAG    E +  E  G +  +S++   
Sbjct: 220  GENAST--------PSEPEKFPQ-----VRRQRGAGAGEGEFVCGEC-GKAFRQSSSLTL 265

Query: 1537 -----EKRSSEKSDDDKKPKTDSPKSVASK---ADKRKKVCSVCNKRFWSLQDLTRHMRS 1588
                  +  + K D+  K  T S   +  +     ++   C  C K F     L  H R 
Sbjct: 266  HRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTGEKPFFCGECGKAFSCHSSLNVHQRI 325

Query: 1589 HTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            HTGERPYKC  CE+ F+    L  H R+H
Sbjct: 326  HTGERPYKCSACEKAFSCSSLLSMHLRVH 354



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 24/49 (48%), Positives = 31/49 (63%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIH 1617
            CS C K F S   LT H R+HTGE+P+KC  C + F+    L+ H+RIH
Sbjct: 418  CSDCEKAFNSRSRLTLHQRTHTGEKPFKCADCGKGFSCHAYLLVHRRIH 466



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 60/245 (24%), Positives = 91/245 (37%), Gaps = 52/245 (21%)

Query: 1445 EQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETP 1504
            E+   C  CGK+F     L+RH + H  ++P      G +          E+        
Sbjct: 357  EKPYRCGECGKAFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIH------ 410

Query: 1505 AEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSS----EKSDDDKKPK--TDSPKSV 1558
                     +G+ P +         SD E A   RS     +++   +KP    D  K  
Sbjct: 411  ---------SGDKPFKC--------SDCEKAFNSRSRLTLHQRTHTGEKPFKCADCGKGF 453

Query: 1559 ASKA----------DKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKH 1608
            +  A           ++   C+ C K F S   L  H R HTGE+P+ C  C + F+   
Sbjct: 454  SCHAYLLVHRRIHSGEKPFKCNECGKAFSSHAYLIVHRRIHTGEKPFDCSQCWKAFSCHS 513

Query: 1609 SLVRHQRIHQKARHAKHHGKDSDKEERGEEDSEN------ESTHSGNNAVSENEAELAPN 1662
            SL+ HQRIH   +  K         E G   S+N      +  HSG  +    +     N
Sbjct: 514  SLIVHQRIHTGEKPYK-------CSECGRAFSQNHCLIKHQKIHSGEKSFKCEKCGEMFN 566

Query: 1663 ASNHM 1667
             S+H+
Sbjct: 567  WSSHL 571



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 13/130 (10%)

Query: 1508 VESAPGAGEAPAEKLA-EETEGPSDGESAAEKRSSEKS----------DDDKKPKTDSPK 1556
            V++  G  +APA   A E    PS+ E   + R    +          +  K  +  S  
Sbjct: 204  VQATEGRTKAPARLCAGENASTPSEPEKFPQVRRQRGAGAGEGEFVCGECGKAFRQSSSL 263

Query: 1557 SVASKADKRKKV--CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQ 1614
            ++  +   R+K   C  C K F    +L  H R HTGE+P+ C  C + F+   SL  HQ
Sbjct: 264  TLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTGEKPFFCGECGKAFSCHSSLNVHQ 323

Query: 1615 RIHQKARHAK 1624
            RIH   R  K
Sbjct: 324  RIHTGERPYK 333



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 5/82 (6%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R H G  P+ C+ C    +  ++LI H R H+GE+PY C 
Sbjct: 472 FKCNECGKAFSSHAYLIVHRRIHTGEKPFDCSQCWKAFSCHSSLIVHQRIHTGEKPYKCS 531

Query: 703 ICHYPFTVKANCERHLRKKHLK 724
            C   F+     + H   KH K
Sbjct: 532 ECGRAFS-----QNHCLIKHQK 548



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 24/77 (31%), Positives = 37/77 (48%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICK 702
           + C  C + F+    L  H R H G  PY+C+ C    +    LI+H + HSGE+ + C+
Sbjct: 500 FDCSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQNHCLIKHQKIHSGEKSFKCE 559

Query: 703 ICHYPFTVKANCERHLR 719
            C   F   ++   H R
Sbjct: 560 KCGEMFNWSSHLTEHQR 576



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 57/264 (21%), Positives = 96/264 (36%), Gaps = 22/264 (8%)

Query: 120 SGERPYKCTVCGQSFTTNGNMHRHMKIHEK------DPNSATATAPPSPLKRRRLSSKRK 173
           +GE  + C  CG++F  + ++  H + H +      D      T   + L+ RR+ +  K
Sbjct: 243 AGEGEFVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTGEK 302

Query: 174 LSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-D 232
                E  +     +   V            +  + C  C K F C   L  H+  H+ +
Sbjct: 303 PFFCGECGKAFSCHSSLNVH-----QRIHTGERPYKCSACEKAFSCSSLLSMHLRVHTGE 357

Query: 233 NPLRCDICCVTFRTHRGLLRHNALVHKQLPRD--AMGRPF-IQNNPSIPAGFHDLGFTDF 289
            P RC  C   F     L RH+ +   + P    + G+ F   ++ ++    H  G   F
Sbjct: 358 KPYRCGECGKAFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIHS-GDKPF 416

Query: 290 SCRKFPRISQAWCETNL-RRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKP 348
            C    +   +     L +R  + +  F C  C K F     L +H++ H       EKP
Sbjct: 417 KCSDCEKAFNSRSRLTLHQRTHTGEKPFKCADCGKGFSCHAYLLVHRRIH-----SGEKP 471

Query: 349 QATPLPGDALDQKGFLALLGLQHT 372
                 G A     +L +    HT
Sbjct: 472 FKCNECGKAFSSHAYLIVHRRIHT 495



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 58/246 (23%), Positives = 85/246 (34%), Gaps = 38/246 (15%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVT--TCSLR 1305
            C  C + F W+++L  H   HTG+KPF C +C   FS  S+   HQ    G     CS  
Sbjct: 278  CDECGKAFTWSTNLLEHRRIHTGEKPFFCGECGKAFSCHSSLNVHQRIHTGERPYKCSAC 337

Query: 1306 RNGLIPQSKES-DVGSHDSTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDA 1364
                   S  S  +  H         E   A  +   LT   R    E   +        
Sbjct: 338  EKAFSCSSLLSMHLRVHTGEKPYRCGECGKAFNQRTHLTRHHRIHTGEKPYQCGSCG--- 394

Query: 1365 PVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKL 1424
              +  T  ++  VH + H   +  +                 E+  +S   L L   T  
Sbjct: 395  --KAFTCHSSLTVHEKIHSGDKPFK-------------CSDCEKAFNSRSRLTLHQRTHT 439

Query: 1425 MD--FKLAEGDGEAGAGGAA-----------SQEQKLACDTCGKSFKFLGTLSRHRKAHG 1471
             +  FK A    + G G +            S E+   C+ CGK+F     L  HR+ H 
Sbjct: 440  GEKPFKCA----DCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKAFSSHAYLIVHRRIHT 495

Query: 1472 RQEPKD 1477
             ++P D
Sbjct: 496  GEKPFD 501



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 18/53 (33%), Positives = 28/53 (52%)

Query: 1569 CSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKAR 1621
            CS C + F     L +H + H+GE+ +KC+ C   F     L  HQR+H + +
Sbjct: 530  CSECGRAFSQNHCLIKHQKIHSGEKSFKCEKCGEMFNWSSHLTEHQRLHSEGK 582



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 35/150 (23%), Positives = 49/150 (32%), Gaps = 40/150 (26%)

Query: 667 GISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKAT 726
           G   + C  C       ++L  H R HS E+ Y C  C   FT   N   H R   +   
Sbjct: 244 GEGEFVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRR---IHTG 300

Query: 727 RKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKG 786
            K                          C  CG+    + +L +H R          H G
Sbjct: 301 EKPF-----------------------FCGECGKAFSCHSSLNVHQRI---------HTG 328

Query: 787 RKPFECKECSAAFAAKRNCIHHILKQHLHV 816
            +P++C  C  AF+        +L  HL V
Sbjct: 329 ERPYKCSACEKAFSCS-----SLLSMHLRV 353



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 17/46 (36%), Positives = 23/46 (50%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C R F     L +H   H+G+K F C+KC   F+  S+   HQ
Sbjct: 530  CSECGRAFSQNHCLIKHQKIHSGEKSFKCEKCGEMFNWSSHLTEHQ 575



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 18/46 (39%), Positives = 23/46 (50%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   SSL  H   HTG+KP+ C +C   FS      +HQ
Sbjct: 502  CSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQNHCLIKHQ 547



 Score = 37.7 bits (86), Expect = 0.098
 Identities = 18/46 (39%), Positives = 23/46 (50%)

Query: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C  C + F   + L  H   HTG+KPF C +C   FS  S+   HQ
Sbjct: 474  CNECGKAFSSHAYLIVHRRIHTGEKPFDCSQCWKAFSCHSSLIVHQ 519



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 39/163 (23%), Positives = 64/163 (39%), Gaps = 8/163 (4%)

Query: 1138 AASPTEQGPAGTSKKRGRKRGMRSR----PRANSGGVDLDSS-GEFASIEKMLATTDTNK 1192
            A  P  + P G ++  GR+ G   R    P A +  +  D    EF     + A     +
Sbjct: 134  AQEPIMERPLGGAQAWGRQAGALQRSQAAPWAPAPAMVWDVPVEEFPLRCPLFAQQRVPE 193

Query: 1193 FSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPE-DKLLRAKRNSYTNCLQ-KITCPH 1250
              P L T + N Q       A     + E   +P E +K  + +R       + +  C  
Sbjct: 194  GGPLLDTRK-NVQATEGRTKAPARLCAGENASTPSEPEKFPQVRRQRGAGAGEGEFVCGE 252

Query: 1251 CPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQ 1293
            C + F  +SSL  H   H+ +K + C +C   F+  +N   H+
Sbjct: 253  CGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHR 295



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 56  NQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRH 115
           +Q     +  Y C  C +  +  H L  H + H+   G     C  CG+  + +S L  H
Sbjct: 518 HQRIHTGEKPYKCSECGRAFSQNHCLIKHQKIHS---GEKSFKCEKCGEMFNWSSHLTEH 574

Query: 116 MLVHSGERP 124
             +HS  +P
Sbjct: 575 QRLHSEGKP 583



 Score = 33.5 bits (75), Expect = 1.9
 Identities = 16/56 (28%), Positives = 25/56 (44%)

Query: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERP 698
           Y C  C + F+ +  L  H + H G   ++C  C  +    + L  H R HS  +P
Sbjct: 528 YKCSECGRAFSQNHCLIKHQKIHSGEKSFKCEKCGEMFNWSSHLTEHQRLHSEGKP 583


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,071,405
Number of Sequences: 37866
Number of extensions: 4867091
Number of successful extensions: 123737
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1279
Number of HSP's successfully gapped in prelim test: 1591
Number of HSP's that attempted gapping in prelim test: 24663
Number of HSP's gapped (non-prelim): 57280
length of query: 1742
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1626
effective length of database: 13,855,062
effective search space: 22528330812
effective search space used: 22528330812
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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