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Search of human proteins with 5032223
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5032223 plexin C1 [Homo sapiens]
(1568 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5032223 plexin C1 [Homo sapiens] 3168 0.0
gi|157694524 plexin D1 [Homo sapiens] 539 e-153
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 423 e-118
gi|113722116 plexin A2 [Homo sapiens] 422 e-117
gi|49355818 plexin A1 [Homo sapiens] 421 e-117
gi|149363636 plexin B2 [Homo sapiens] 407 e-113
gi|194272180 plexin B1 [Homo sapiens] 405 e-112
gi|40254442 plexin B1 [Homo sapiens] 405 e-112
gi|59710104 plexin A3 [Homo sapiens] 404 e-112
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 384 e-106
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 384 e-106
gi|39777610 semaphorin 4B precursor [Homo sapiens] 58 6e-08
gi|39777608 semaphorin 4B precursor [Homo sapiens] 58 6e-08
gi|19923279 semaphorin W [Homo sapiens] 58 8e-08
gi|157388902 semaphorin 4C [Homo sapiens] 58 8e-08
gi|21361914 semaphorin B [Homo sapiens] 55 4e-07
gi|28872814 semaphorin 4G [Homo sapiens] 55 7e-07
gi|9910362 semaphorin sem2 [Homo sapiens] 51 1e-05
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 50 1e-05
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 50 1e-05
gi|6912650 semaphorin 3E [Homo sapiens] 49 3e-05
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 48 8e-05
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 48 8e-05
gi|5174673 semaphorin 3A precursor [Homo sapiens] 46 3e-04
gi|147904700 semaphorin 5A [Homo sapiens] 45 7e-04
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 44 0.001
gi|5454048 semaphorin 3C [Homo sapiens] 44 0.002
gi|16306552 semaphorin Y [Homo sapiens] 43 0.002
gi|188497703 semaphorin 3F [Homo sapiens] 43 0.003
gi|41406086 semaphorin 3D [Homo sapiens] 41 0.008
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 3168 bits (8213), Expect = 0.0
Identities = 1568/1568 (100%), Positives = 1568/1568 (100%)
Query: 1 MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRGADEPVWRSEQAIGAIAASQEDGVFVA 60
MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRGADEPVWRSEQAIGAIAASQEDGVFVA
Sbjct: 1 MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRGADEPVWRSEQAIGAIAASQEDGVFVA 60
Query: 61 SGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLG 120
SGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLG
Sbjct: 61 SGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLG 120
Query: 121 GLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQGSTAGVVYRAGRNNRWYLAVA 180
GLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQGSTAGVVYRAGRNNRWYLAVA
Sbjct: 121 GLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQGSTAGVVYRAGRNNRWYLAVA 180
Query: 181 ATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLW 240
ATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLW
Sbjct: 181 ATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLW 240
Query: 241 NGSIYFPYYPYNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLV 300
NGSIYFPYYPYNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLV
Sbjct: 241 NGSIYFPYYPYNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLV 300
Query: 301 EALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQP 360
EALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQP
Sbjct: 301 EALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQP 360
Query: 361 ERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIK 420
ERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIK
Sbjct: 361 ERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIK 420
Query: 421 EETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQR 480
EETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQR
Sbjct: 421 EETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQR 480
Query: 481 CTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVD 540
CTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVD
Sbjct: 481 CTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVD 540
Query: 541 SSRELCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPA 600
SSRELCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPA
Sbjct: 541 SSRELCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPA 600
Query: 601 CVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGGRPKENKGNRTNQALQ 660
CVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGGRPKENKGNRTNQALQ
Sbjct: 601 CVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGGRPKENKGNRTNQALQ 660
Query: 661 VFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMK 720
VFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMK
Sbjct: 661 VFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMK 720
Query: 721 FSLPSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFD 780
FSLPSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFD
Sbjct: 721 FSLPSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFD 780
Query: 781 VIDNLIISHELKGNINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQY 840
VIDNLIISHELKGNINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQY
Sbjct: 781 VIDNLIISHELKGNINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQY 840
Query: 841 REDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQ 900
REDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQ
Sbjct: 841 REDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQ 900
Query: 901 DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPVLLVIVIF 960
DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPVLLVIVIF
Sbjct: 901 DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPVLLVIVIF 960
Query: 961 AAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKH 1020
AAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKH
Sbjct: 961 AAVGVTRHKSKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKH 1020
Query: 1021 FALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFS 1080
FALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFS
Sbjct: 1021 FALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFS 1080
Query: 1081 VKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNW 1140
VKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNW
Sbjct: 1081 VKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNW 1140
Query: 1141 MSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVA 1200
MSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVA
Sbjct: 1141 MSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVA 1200
Query: 1201 LNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLEL 1260
LNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLEL
Sbjct: 1201 LNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLEL 1260
Query: 1261 QMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHC 1320
QMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHC
Sbjct: 1261 QMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHC 1320
Query: 1321 HLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRA 1380
HLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRA
Sbjct: 1321 HLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSRA 1380
Query: 1381 PFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDG 1440
PFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDG
Sbjct: 1381 PFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDG 1440
Query: 1441 CLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEM 1500
CLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEM
Sbjct: 1441 CLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEM 1500
Query: 1501 EEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFD 1560
EEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFD
Sbjct: 1501 EEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKVLFD 1560
Query: 1561 EKKKCKWM 1568
EKKKCKWM
Sbjct: 1561 EKKKCKWM 1568
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 539 bits (1388), Expect = e-153
Identities = 347/952 (36%), Positives = 521/952 (54%), Gaps = 94/952 (9%)
Query: 664 IKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSL 723
+ S+EP G + + + G + S + +++ T C + + DT + ++
Sbjct: 983 VHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTE------LMRTDTSIACTM 1036
Query: 724 PSSRKEMK-DVCIQFDGGNCSSVGSLS--YIALPHCSLIFPATTWISGGQNITMMGRNFD 780
P VC++F+ C G+L+ Y+ P + I P + +SGG+ IT+ G F
Sbjct: 1037 PEGALPAPVPVCVRFERRGCVH-GNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFH 1095
Query: 781 VIDNLIIS-HELKGNINVSEYCVATYCGFLAP-SLKSSKVRTNVTVKLR-------VQDT 831
++ N+ ++ H + + + +T +P +L ++ + + R V +
Sbjct: 1096 MVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEE 1155
Query: 832 YLDCGTLQ--------YREDPRFTGYRVESEVDTE----LEVKIQKENDNFNISKKDIEI 879
LD Q Y +P+F+ + E + L + I KE D+ + + +
Sbjct: 1156 LLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRV 1215
Query: 880 TLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGN-------L 932
+ GQ++C + ++ I C + A+ + +++GN L
Sbjct: 1216 KI-----GQVSCDIQIVSDR----IIHCSVNESLGAAV---GQLPITIQVGNFNQTIATL 1263
Query: 933 ELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEI 992
+L + ++ + VL +L V+ +F +R +++ +K Q+E +ES++R+EI
Sbjct: 1264 QLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSR-RAERYWQKTLLQMEEMESQIREEI 1322
Query: 993 RDGFAELQMDKLDVVDSFGT---VPFLDYKHFALRTFFPESGGF---THIFTEDMHNRDA 1046
R GFAELQ D D+ +PFL+YKHF RTFFP+ ++ N
Sbjct: 1323 RKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQG 1382
Query: 1047 NDK---------------------NESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRC 1085
+ + E ++ +L+ NK FL+ +H LE+QK+F+V+DRC
Sbjct: 1383 SSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRC 1442
Query: 1086 LFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCL 1145
AS LTIAL KL Y TSI++ L DL++ + PKLMLRRTESVVEK+LTNWMS+C+
Sbjct: 1443 SLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICM 1502
Query: 1146 SGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVF 1205
LRETVGEPF+LL+ + Q+INKG +D IT KA YTLNE+WLL + E LNV F
Sbjct: 1503 YSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSF 1562
Query: 1206 EKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTR 1265
+ + ++SV +D DT+ Q KEKI +AF + ++ LE +
Sbjct: 1563 QGCGMD-------SLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASST 1615
Query: 1266 QKELL-DIDSSSVILEDGITKLNTIGHYEISNGSTI--KVFKKIANFTSDVEYSD--DHC 1320
Q +L D+D +SV+ EDG KLNT+ HY+I G+++ + K N V+ D +
Sbjct: 1616 QSYILRDLDDTSVV-EDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDLDTEKYF 1674
Query: 1321 HLILPDSEAFQDVQGKRHRGKHKFKV-KEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSR 1379
HL+LP E + K HR H+ KV E+YLT+LLSTK + L+ LF++I S+ +
Sbjct: 1675 HLVLPTDELAE--PKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDK 1732
Query: 1380 APFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHID 1439
P A+KYFFDFL+ QAE + I+DPD +HIWKTNSLPLRFWVNILKNPQFVFDI KT HID
Sbjct: 1733 PPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHID 1792
Query: 1440 GCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSE 1499
CLSVIAQAF+DA S+++ QLGK++PTNKLLYAK+IP Y++ V+ YYK I+D+ PLS E
Sbjct: 1793 ACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQE 1852
Query: 1500 MEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQ 1551
M L +ES+K++NEFN VA+ EIYKY +Y +I+ LE Q Q
Sbjct: 1853 MNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQ 1904
Score = 132 bits (332), Expect = 3e-30
Identities = 190/748 (25%), Positives = 289/748 (38%), Gaps = 136/748 (18%)
Query: 9 PPRPPRPAAPLPLLAYLLALAAPGRGADE-------PVWRSEQAIGAIAASQEDGVFVAS 61
PP P P+PLL LL L A GA E P + A+ A + V++A+
Sbjct: 21 PPFQTPPRCPVPLLLLLL-LGAARAGALEIQRRFPSPTPTNNFALDGAAGT----VYLAA 75
Query: 62 GSCLDQL---DYSLEHSLSRLYRDQAGNCTEP-VSLAPPARPRPGSSFSKLLLPYREGAA 117
+ L QL + SLE + + C P + A PR + +L G
Sbjct: 76 VNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQ- 134
Query: 118 GLGGLLLTGWTFDRGACEVRPLGNLSRNSLR---------------NGTEVVSCHPQGST 162
GL++ + +G C++R GN+S ++R + V + HP ST
Sbjct: 135 ---GLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNAST 191
Query: 163 AGVVY--RAGRNNRWYLAVAATYVLPEPETASRCNPAASDH------DTAIALKDTEG-- 212
G+V AG L V ATY R N + DH + AI DT G
Sbjct: 192 VGLVLPPAAGAGGS-RLLVGATYTGYGSSFFPR-NRSLEDHRFENTPEIAIRSLDTRGDL 249
Query: 213 RSLATQELGR-----LKLCEGAGSLH---FVDAFLWN-----GSIYFPYYPYNYTSGAAT 259
L T +L LK+ +GA H FV AFL G+ + Y N + A
Sbjct: 250 AKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALN-SEARAG 308
Query: 260 GWPSMARIAQSTEVLFQG-------------QASLDCGHGHPDGRRLLLSSSLVEALDVW 306
S AR + L G Q L C G G S+ A +
Sbjct: 309 DKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERL 368
Query: 307 AGVFSAAAGEGQERRSPTTTALCLFRMSEIQA--RAKRVSWDFKTAESHCKEGD------ 358
VF G R +P ALC FR ++++A RA R + + A D
Sbjct: 369 FAVFERPQGSPAARAAPA--ALCAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQGT 426
Query: 359 ------------QPERV--------------QPIASSTLIHSD-LTSVYGTVVMNRTVLF 391
QPE++ QP+ ++ + + LTSV V N T +F
Sbjct: 427 GPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLTSVAVASVNNYTAVF 486
Query: 392 LGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIR 451
LGT +G+LLK+ L E++ V+ E PV + + DP + Y+YL ++ R++
Sbjct: 487 LGTVNGRLLKINLNESMQVVSRRVVTVAYGE-PVHHVMQFDPADSGYLYLMTSHQMARVK 545
Query: 452 VANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI 511
VA CN H +C +C+ A D +CGWC RCT Q DC +S W S G +CP + +
Sbjct: 546 VAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTV 605
Query: 512 IRSS----KEKTTVTM-----VGSFSPRHSKCMVKNVDSSRELCQNKSQPNRTCTCSIPT 562
+ S +E + + + S S C N + + ++ C++
Sbjct: 606 LPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLP 665
Query: 563 RATY------KDVSVVNVMFSFGSWNL-SDRFNFTNCSSLKE------CPACV--ETGCA 607
R + +D V + N+ F +CS + C +C+ + C
Sbjct: 666 RDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCF 725
Query: 608 WCKSARRCIHPFTACDPSDYERNQEQCP 635
WC C+ + C+ S + + CP
Sbjct: 726 WCSQQHSCVSNQSRCEASPNPTSPQDCP 753
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 423 bits (1088), Expect = e-118
Identities = 313/966 (32%), Positives = 490/966 (50%), Gaps = 110/966 (11%)
Query: 664 IKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSL 723
+ ++P + G + V +TG N SN+ +++ G C + H + +++ +
Sbjct: 956 LSDLKPSRGPMSGGTQVTITGTNLNAGSNV-VVMFGKQPC------LFHRRSPSYIVCNT 1008
Query: 724 PSSRK--EMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDV 781
SS + EMK V +Q D Y+ P I P + +SG I + G + D+
Sbjct: 1009 TSSDEVLEMK-VSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDL 1067
Query: 782 IDNLII--SHELKGNINVSEYCVATYCGFLAPSLKSSK---------------VRTNVTV 824
I N I H K +IN+ E AT AP+L + NV
Sbjct: 1068 IQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQS 1127
Query: 825 KLRVQDTYLDCGTLQYREDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHG 884
L + T Y +P F + ++ + I + N I G
Sbjct: 1128 LLILNKT-----NFTYYPNPVFEAFGPSGILELKPGTPIILKGKNL--------IPPVAG 1174
Query: 885 ENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLE-----LYVEQE 939
N +LN + + + T + ++ + + + K V ++G +E +Y+ +
Sbjct: 1175 GNVKLN--YTVLVGEKPCTVTVSDVQLLCESPNLIGRHK-VMARVGGMEYSPGMVYIAPD 1231
Query: 940 SVPSTWYFLIVLPV---LLVIVIFAAVGVTRHKSKE--LSRKQSQ-QLELLESELRKEIR 993
S P + ++ + V LL+I I A + + KS+E L+ K+ Q Q++ LES + E +
Sbjct: 1232 S-PLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECK 1290
Query: 994 DGFAELQMDKLDVVDSF--GTVPFLDYKHFALRTFFPESGGFTHIFTEDM----HNRDAN 1047
+ FAELQ D ++ +PFLDY+ + +R FP G H D+ + ++
Sbjct: 1291 EAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFP--GIEDHPVLRDLEVPGYRQERV 1348
Query: 1048 DKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILE 1107
+K L A LI NK FL++ I TLE Q++FS++DR AS + LQ+KL Y T +L+
Sbjct: 1349 EKGLKLFA--QLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLK 1406
Query: 1108 VLTRDLMEQC--SNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLN 1165
L DL+++ S PKL+LRRTESV EK+LTNW + L FL+E GEP + L +
Sbjct: 1407 QLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIK 1466
Query: 1166 QKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVL 1225
Q++ KGP+D IT +A Y+L+ED L+ Q ++ T+ L+ V P+N ++ + V +L
Sbjct: 1467 QQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSCVS---PDNANSP---EVPVKIL 1520
Query: 1226 DCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITK 1285
+CDTI Q KEKI A + + ++ LE + G+ + +L + + +E+ +
Sbjct: 1521 NCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKR 1580
Query: 1286 LNTIGHYEISNGSTIKVFKK-----------------------IANFTSDVEYSDDHCHL 1322
LNT+ HY++ +GS + + K + +T + +
Sbjct: 1581 LNTLAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPM 1640
Query: 1323 ILPDSEAFQDV--------QGKRHRGKHKFK-VKEMYLTKLLSTKVAIHSVLEKLFRSIW 1373
I PD E+ + G + G K V E+YLT+LL+TK + ++ LF +I+
Sbjct: 1641 ITPDLESGVKMWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIF 1700
Query: 1374 SLPN--SRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFD 1431
S + S P AIKY FDFLD QA+ I DP V H WK+N LPLRFWVN++KNPQFVFD
Sbjct: 1701 STAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFD 1760
Query: 1432 IKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRD 1491
I K D CLSV+AQ FMD+ S +E +LGK++P+NKLLYAKDIP+YK V+ YY I
Sbjct: 1761 IHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGK 1820
Query: 1492 LPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQ 1551
+P +S +M +L ++S+ H NEFN AL+EI+ Y+ KY +EIL L+ + ++ KQ
Sbjct: 1821 MPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHD---DQCGKQ 1877
Query: 1552 LLHVKV 1557
L K+
Sbjct: 1878 KLAYKL 1883
Score = 83.2 bits (204), Expect = 2e-15
Identities = 90/377 (23%), Positives = 149/377 (39%), Gaps = 52/377 (13%)
Query: 304 DVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKR-------------VSWDFKTA 350
D+ VFS G+ ++ +S +ALC+F + +I R K ++W K
Sbjct: 333 DLLFTVFSK--GQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAW-LKVK 389
Query: 351 ESHCKEG-----------------DQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLG 393
+ C + V+ I T +TSV V N ++ F+G
Sbjct: 390 DIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVG 449
Query: 394 TGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVA 453
T G+L K+ + + ++ + PV + + +Y+ + +++ R+ V
Sbjct: 450 TKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSK-DHEQLYIMSERQLTRVPVE 508
Query: 454 NCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI-- 511
+C +++SC ECL + DPHCGWC CT + C S+ + +S K+C ++ +
Sbjct: 509 SCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRF---ASEMKQCVRLTVHP 565
Query: 512 --IRSSKEKTTVTMVGSFSPRHS---KCMVKNVDSSREL-CQNKSQPNRTCTCSIPTRAT 565
I S+ + + P S C +++ L N+ Q +P T
Sbjct: 566 NNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIIT 625
Query: 566 YK-DVSVVNVMF---SFGSWNLSDRFNFTNCSSLKECPACVET--GCAWCKSARRCIH-P 618
D VV + G S F F NCS C +CVE+ C WCK C H P
Sbjct: 626 ENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDP 685
Query: 619 FTACDPSDYERNQEQCP 635
T + E CP
Sbjct: 686 KTCSFQEGRVKLPEDCP 702
Score = 40.0 bits (92), Expect = 0.018
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 3/54 (5%)
Query: 459 KSCSECLTAT-DPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI 511
+SC CL A D CGWC +CT + C E+ WL++S KC +I
Sbjct: 809 ESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQES--QWLELSGAKSKCTNPRI 860
Score = 34.3 bits (77), Expect = 0.97
Identities = 37/184 (20%), Positives = 72/184 (39%), Gaps = 28/184 (15%)
Query: 454 NCNKHKSCSECLTATDPHCGWC-------HSLQRCTFQ-GDCVHSENLENWLDISSGAKK 505
NC+ H SC C+ + C WC H + C+FQ G E+ L + K
Sbjct: 655 NCSVHNSCLSCV-ESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVD---KI 710
Query: 506 CPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELCQNKSQPNRTCTCSIPTRAT 565
+++I+ K R +C++ N+ S + + + C T +
Sbjct: 711 LVPVEVIKPITLKAKNLPQPQSGQRGYECIL-NIQGSEQRVPALRFNSSSVQCQ-NTSYS 768
Query: 566 YKDVSVVNVMFSF-----GSWNL----SDRFNFTNCSSLKE-CPACVET----GCAWCKS 611
Y+ + + N+ G +N+ ++ + C +++E C C++ C WC+
Sbjct: 769 YEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQG 828
Query: 612 ARRC 615
+C
Sbjct: 829 PGQC 832
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 422 bits (1084), Expect = e-117
Identities = 323/960 (33%), Positives = 488/960 (50%), Gaps = 98/960 (10%)
Query: 664 IKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSL 723
+ S+ P + G + V +TG S++ + L G TC+ +S ++ S
Sbjct: 956 VLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYL-GNQTCEFYGRSMSEIVC-----VSP 1009
Query: 724 PSSRK-EMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVI 782
PSS V + D + S YI P I P + SG +T+ G N DVI
Sbjct: 1010 PSSNGLGPVPVSVSVDRAHVDSNLQFEYIDDPRVQRIEPEWSIASGHTPLTITGFNLDVI 1069
Query: 783 DNLIISHELKG--NINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQD---TYLDCGT 837
I + G ++NV + T LAPSL ++ R + R + + + +
Sbjct: 1070 QEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSL-TTDYRPGLDTVERPDEFGFVFNNVQS 1128
Query: 838 LQYREDPRFTGYRVES-EVDTELEVKIQKENDNFNISKKDIEITLFHGEN-------GQL 889
L D +F Y + E+ + V QK + K++ G G+
Sbjct: 1129 LLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGET 1188
Query: 890 NCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLI 949
C+ +T ++ T +LC+ + KV V +G + SV S L+
Sbjct: 1189 PCA---VTVSE--TQLLCEPPNL-------TGQHKVMVHVGGMVFSPGSVSVISD--SLL 1234
Query: 950 VLP----------VLLVIVIFAAVGVTRH-KSKELSRKQSQ-QLELLESELRKEIRDGFA 997
LP +LL+IVI + R + +L+ K+ Q Q++ LES + E ++ FA
Sbjct: 1235 TLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFA 1294
Query: 998 ELQMDKLDVVDSFGT--VPFLDYKHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTA 1055
ELQ D ++ +P+LDY+ +A+R FP + ++ ++L
Sbjct: 1295 ELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEKALKL 1354
Query: 1056 LDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLME 1115
LI NK FL+T I TLE Q++FS++DR AS + LQ +L Y T +L+ L DL++
Sbjct: 1355 FAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLID 1414
Query: 1116 QC--SNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPV 1173
+ + PKL+LRRTESV EK+LTNW + L FL+E GEP ++L + Q++ KGP+
Sbjct: 1415 KNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPI 1474
Query: 1174 DVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQA 1233
D IT +A Y+L+ED L+ Q E+ T+ LN V P+NE++ I V VL+CDTI Q
Sbjct: 1475 DAITGEARYSLSEDKLIRQQIEYKTLILNCVN---PDNENSP---EIPVKVLNCDTITQV 1528
Query: 1234 KEKIFQAFLSKNGSPYGLQLNEIGLELQ--MGTRQKELLDIDSSSVILEDGITKLNTIGH 1291
KEKI A + KN PY + + ++L+ G + +L + + +E +LNT+ H
Sbjct: 1529 KEKILDA-VYKN-VPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMH 1586
Query: 1292 YEISNGSTIKVFKK-----------------IANFTSDVEYSDD------HCHLILPDSE 1328
Y++S+ S + + K I+ + S Y+ +I PD E
Sbjct: 1587 YQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLE 1646
Query: 1329 AFQDV--------QGKRHRGKHKFK-VKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPN-- 1377
+ V G + G K V E+YLT+LL+TK + ++ LF +++S +
Sbjct: 1647 SGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVHRG 1706
Query: 1378 SRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPH 1437
S P AIKY FDFLD QA+ I D DV H WK+N LPLRFWVN++KNPQFVFDI K
Sbjct: 1707 SALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSI 1766
Query: 1438 IDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSS 1497
D CLSV+AQ FMD+ S +E +LGK++P+NKLLYAKDIP+YK V+ YY I LP +S
Sbjct: 1767 TDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAISD 1826
Query: 1498 SEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKV 1557
+M +L ++S+ H EFN AL EIY Y+ KY +E++ LE++ E+A++Q L KV
Sbjct: 1827 QDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQD---EQARRQRLAYKV 1883
Score = 93.6 bits (231), Expect = 1e-18
Identities = 94/397 (23%), Positives = 160/397 (40%), Gaps = 58/397 (14%)
Query: 290 GRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKR------- 342
G L + ++ DV +FS G+ Q P +ALC F + I + K
Sbjct: 319 GDSLAQAFNITSQDDVLFAIFSK--GQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQ 376
Query: 343 ------VSWDFKTAESHCKEGDQP--------ERVQPIASSTLIHS---------DLTSV 379
++W + C + P + QP+ ST + +TSV
Sbjct: 377 GEGNLELNW-LLGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSV 435
Query: 380 YGTVVMNRTVLFLGTGDGQLLKVIL-GENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIY 438
V +V+F+GT G+L K+ G E++ +K+ +P+ + + Y
Sbjct: 436 ASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFS-IDQRY 494
Query: 439 IYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLD 498
+Y+ + ++V R+ V +C ++ +C ECL++ DPHCGWC C+ + C + +
Sbjct: 495 LYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRF-- 552
Query: 499 ISSGAKKCPKIQI----IRSSKEKTTVTMVGSFSPRHS---KCMVKN-------VDSSRE 544
++ +C + + I S+ +++V S +P S C N V S+
Sbjct: 553 -AASISQCVSLAVHPSSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLTEVEGQVSGSQV 611
Query: 545 LCQNKSQPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPACVET 604
+C P IP + + + G +S F F NCS+ + C +CV +
Sbjct: 612 IC---ISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVNS 668
Query: 605 G--CAWCKSARRCIHPFTACDPSDYERN-QEQCPVAV 638
C WCK C H T C + N E CP V
Sbjct: 669 AFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLV 705
Score = 40.0 bits (92), Expect = 0.018
Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 457 KHKSCSECLTATDP-HCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI 511
+ +SC CL A CGWC +RCT C + WLD SS KC QI
Sbjct: 807 QRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSS--PWLDWSSHNVKCSNPQI 860
Score = 35.0 bits (79), Expect = 0.57
Identities = 52/236 (22%), Positives = 85/236 (36%), Gaps = 60/236 (25%)
Query: 454 NCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKI---- 509
NC+ H+ C C+ + C WC CT D E ++IS + CP++
Sbjct: 655 NCSAHQLCLSCVNSAF-RCHWCKYRNLCTH--DPTTCSFQEGRINIS---EDCPQLVPTE 708
Query: 510 QIIRSSKEKTTVTMVGSFSP------RHSKCMVK-----------NVDSSRELCQNKSQP 552
+I+ E +T+ P R +C++ +SS CQN S
Sbjct: 709 EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNSSYQ 768
Query: 553 NRTCTCSIPTRATYKDVSVVNVMFSFGS-WN---LSD-----RFNFTNCSSLKE-CPACV 602
Y + + N+ F WN + D + + C++ +E C C+
Sbjct: 769 -------------YDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCL 815
Query: 603 ETG----CAWCKSARRCIHPFTACDPS----DYERNQEQC--PVAVEKTSGGGRPK 648
+ C WC RRC PS D+ + +C P E + G P+
Sbjct: 816 KADRKFECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPE 871
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 421 bits (1083), Expect = e-117
Identities = 267/706 (37%), Positives = 398/706 (56%), Gaps = 75/706 (10%)
Query: 903 TTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPV--------- 953
T +LC+ + + + G L++Y + L+ LP
Sbjct: 1181 TQLLCEAPNLTGQHKVTVRAGGFEFSPGTLQVYSDS---------LLTLPAIVGIGGGGG 1231
Query: 954 LLVIVIFAAVGVTRHKSKELSRKQSQ---QLELLESELRKEIRDGFAELQMDKLDVVDSF 1010
LL++VI A + + KS++ R + Q++ LES + E ++ FAELQ D ++ +
Sbjct: 1232 LLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDL 1291
Query: 1011 --GTVPFLDYKHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVT 1068
+PFLDY+ +A+R FP G H ++M + +K SLT L+ K FL+T
Sbjct: 1292 DGAGIPFLDYRTYAMRVLFP--GIEDHPVLKEMEVQANVEK--SLTLFGQLLTKKHFLLT 1347
Query: 1069 VIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQC--SNMQPKLML 1126
I TLE Q++FS++DR AS + ALQ ++ Y T +L+ L DL+E+ S PKL+L
Sbjct: 1348 FIRTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLL 1407
Query: 1127 RRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNE 1186
RRTESV EK+LTNW + L FL+E GEP ++L + Q++ KGP+D IT +A Y+L+E
Sbjct: 1408 RRTESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSE 1467
Query: 1187 DWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNG 1246
D L+ Q ++ T+ LN V PENE+A + V LDCDT+ QAKEK+ A + G
Sbjct: 1468 DKLIRQQIDYKTLTLNCVN---PENENAP---EVPVKGLDCDTVTQAKEKLLDA--AYKG 1519
Query: 1247 SPYGLQLN--EIGLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFK 1304
PY + ++ LE + G + +L + + +++ +LNT+ HY++++GS++ +
Sbjct: 1520 VPYSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVP 1579
Query: 1305 K------IAN---FTSDVEYSDDHCH-------------LILPDSEAF---------QDV 1333
K I+N FT + + +I PD E+ D
Sbjct: 1580 KQTSAYNISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDH 1639
Query: 1334 QGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPN--SRAPFAIKYFFDFL 1391
+R + V E+YLT+LL+TK + ++ LF +I+S + S P AIKY FDFL
Sbjct: 1640 LDQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFL 1699
Query: 1392 DAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMD 1451
D QA+ +I D DV H WK+N LPLRFWVN++KNPQFVFDI K D CLSV+AQ FMD
Sbjct: 1700 DEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMD 1759
Query: 1452 AFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKH 1511
+ S +E +LGK++P+NKLLYAKDIP YK V+ YY I +P +S +M +L ++S+ H
Sbjct: 1760 SCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLH 1819
Query: 1512 ENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQLLHVKV 1557
++FN AL EIY YI KY DEIL LE++ E+A++Q L K+
Sbjct: 1820 LSQFNSMSALHEIYSYITKYKDEILAALEKD---EQARRQRLRSKL 1862
Score = 89.4 bits (220), Expect = 3e-17
Identities = 95/396 (23%), Positives = 156/396 (39%), Gaps = 47/396 (11%)
Query: 290 GRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKR------- 342
GR L L E DV VF A G+ + P +ALCLF + I+ + K
Sbjct: 298 GRALAHQLGLAEDEDVLFTVF--AQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYR 355
Query: 343 -----------------VSWDFKTAESHC-KEGDQPERVQPIASSTLIHSD----LTSVY 380
++ + + C ++ +QP T + D LT+V
Sbjct: 356 GEGKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVA 415
Query: 381 GTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYE---IKEETPVFYKLVPDPVKNI 437
RTV+F GT G++ K+++ + P + YE +E +P+ LV P +
Sbjct: 416 AYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSP-NHQ 474
Query: 438 YIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENW- 496
Y+Y K+V R+ V +C ++ SC CL + DPHCGWC C+ + C ++ + +
Sbjct: 475 YLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFA 534
Query: 497 LDISSGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHS---KCMVKNVDSSRELCQNKSQPN 553
D+ + + + + + + + + P S C ++ S + ++
Sbjct: 535 ADLLQCVQLTVQPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHC 594
Query: 554 RTCTCS--IPTRATYKDVSVVNVMF---SFGSWNLSDRFNFTNCSSLKECPACVETG--C 606
R+ + P D VV + G S F F NCS + C +CV C
Sbjct: 595 RSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQSCLSCVNGSFPC 654
Query: 607 AWCKSARRCIHPFTACDPSDYERN-QEQCPVAVEKT 641
WCK C H C + N E CP + T
Sbjct: 655 HWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPST 690
Score = 40.4 bits (93), Expect = 0.014
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
Query: 459 KSCSECLTATDPH--CGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQIIRSSK 516
+SC CL A DP CGWC + +RC+ + C ++ +W+ G+ +C +I++ S
Sbjct: 791 ESCGLCLKA-DPRFECGWCVAERRCSLRHHCA-ADTPASWMHARHGSSRCTDPKILKLSP 848
Query: 517 E 517
E
Sbjct: 849 E 849
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 407 bits (1046), Expect = e-113
Identities = 284/851 (33%), Positives = 437/851 (51%), Gaps = 83/851 (9%)
Query: 761 PATTWISGGQNITMMGRNFDVIDN---LIISHELKG-------------NINVSEYCVA- 803
P ++ SGG++I + G+ F +I ++I+ L+ + ++Y
Sbjct: 990 PLRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQPMTVVGTDYVFHN 1049
Query: 804 -TYCGFLAPSLKSSKVRTNVTVKLRVQD----TYLDCGTLQYREDPRFTGYRVESEVDTE 858
T FL+P++ N+TV + + + G +Y DP F + V +
Sbjct: 1050 DTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFT--GGVKKQ 1107
Query: 859 LEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGI------ 912
+ I N N + E F G C+ + +T T + C+ +
Sbjct: 1108 VNKLIHARGTNLNKAMTLQEAEAFVGAE---RCTMKTLTE----TDLYCEPPEVQPPPKR 1160
Query: 913 KTASTIANSSKKVRVKLGNLELY---VEQESVPSTWYFLIVLPVLLV---IVIFAAVGVT 966
+ ++ + VK G+ E VE ++ S ++LP+++V +VI +V
Sbjct: 1161 RQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVYCY 1220
Query: 967 RHKSKELSR---KQSQQLELLESELRKEIRDGFAELQMDKLDVVDSF--GTVPFLDYKHF 1021
KS++ R K QLE LE +R + F +L ++ D + +P LDYK +
Sbjct: 1221 WRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTY 1280
Query: 1022 ALRTFF-PESGGFTHIFTE---DMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQK 1077
R FF P G + D+ ++L L+ +KSFL+ IHTLE Q+
Sbjct: 1281 TDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQR 1340
Query: 1078 NFSVKDRCLFASFLTIALQTKLVYLTSILEVLTRDLMEQ-CSNMQPKLMLRRTESVVEKL 1136
FS + + FAS LT+AL KL Y T I+ L +L+EQ PKLMLRR+E+VVE++
Sbjct: 1341 EFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERM 1400
Query: 1137 LTNWMSVCLSGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEF 1196
L+NWMS+CL +L+++ GEP Y L + ++ KGPVD + KA YTLN+ LL E+
Sbjct: 1401 LSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEY 1460
Query: 1197 STVALNVVFEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEI 1256
+ + ++V+ + +E D I V VL+CDTI Q KEKI + + +
Sbjct: 1461 APLTVSVIVQ----DEGVDA---IPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSV 1513
Query: 1257 GLELQMGTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKK-IANFTSD--- 1312
LE + G+ + L D+D +S E ++NT+ HY + +G+T+ + K ++ D
Sbjct: 1514 VLEWRPGSTAQILSDLDLTSQ-REGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQ 1572
Query: 1313 ---------VEYSDDHCHLILPDSEAFQDVQGKRHRGKHKFK-----VKEMYLTKLLSTK 1358
+E + HL+ P E + GK RG K K + E+YLT+LLS K
Sbjct: 1573 DLPGERHALLEEENRVWHLVRPTDEVDE---GKSKRGSVKEKERTKAITEIYLTRLLSVK 1629
Query: 1359 VAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRF 1418
+ ++ F+S+ + P P A+KYFFDFLD QAE I D D +HIWKTNSLPLRF
Sbjct: 1630 GTLQQFVDNFFQSVLA-PGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRF 1688
Query: 1419 WVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTY 1478
WVNILKNP F+FD+ +D LSVIAQ FMDA + TE +L +++P+NKLLYAK+I TY
Sbjct: 1689 WVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTY 1748
Query: 1479 KEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNK 1538
K+ V+ YYK IR + +S +M L + S+ H + N VAL ++Y+Y KY+DEI+N
Sbjct: 1749 KKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINA 1808
Query: 1539 LERERGLEEAQ 1549
LE + ++ Q
Sbjct: 1809 LEEDPAAQKMQ 1819
Score = 73.6 bits (179), Expect = 1e-12
Identities = 45/133 (33%), Positives = 68/133 (51%), Gaps = 6/133 (4%)
Query: 375 DLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSN-CPEVIYEIKEETPVFYKLVPDP 433
+LT+V N TV FLGT DG++LKV L + TS+ ++ EI + L D
Sbjct: 391 NLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDL 450
Query: 434 VKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENL 493
+Y +V R+ V C + +C++C + DP+CGWC RCT + +C +E
Sbjct: 451 GS---LYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEA 507
Query: 494 ENWLDISSGAKKC 506
+WL S +K C
Sbjct: 508 SHWL--WSRSKSC 518
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 405 bits (1042), Expect = e-112
Identities = 297/891 (33%), Positives = 436/891 (48%), Gaps = 105/891 (11%)
Query: 746 GSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDN-----LIISHELKGNINVSE- 799
G Y P+ + P +++SGG+ I + G+N DV+ ++S L+ + +
Sbjct: 1244 GQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRR 1303
Query: 800 --YCVATYCGFLAPSLKSSKVRTN------------------------VTVKLRVQDTYL 833
T C L PS S + V V+ + +
Sbjct: 1304 RRVVPETACS-LGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVF 1362
Query: 834 DCGTLQ-----YREDPRFTGYRVESEV-----DTELEVKIQKENDNFNISKKDIEITLFH 883
D TL Y DP E ++ EN + +SK+++ +
Sbjct: 1363 DFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGD 1422
Query: 884 GENGQLNCSFENITRNQ-----DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVE- 937
G C + +TR+ + L + ++ A +S + V++GNL +
Sbjct: 1423 GP-----CVVKTLTRHHLYCEPPVEQPLPRHHALREAP---DSLPEFTVQMGNLRFSLGH 1474
Query: 938 -QESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKELSR---KQSQQLELLES 986
Q S F + V LL + + V + R KSK+ R K QLE LES
Sbjct: 1475 VQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLES 1534
Query: 987 ELRKEIRDGFAELQMDKLDVV-DSFGT-VPFLDYKHFALRTFFPESGGFTHIFTEDMHNR 1044
+R + F +L + D+ D G+ +PFLDYK +A R FFP G D+
Sbjct: 1535 SVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFP--GHRESPLHRDLGVP 1592
Query: 1045 DANDKN--ESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYL 1102
++ + L L L+ +K FL IHTLE Q+ FS +DR AS LT+AL KL Y
Sbjct: 1593 ESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYF 1652
Query: 1103 TSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVT 1162
T IL L DL+ Q PKLMLRRTE+VVEKLLTNWMS+CL F+R++VGEP Y+L
Sbjct: 1653 TDILRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFR 1712
Query: 1163 TLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISV 1222
+ +++KGPVD +T KA YTLN++ LL + E+ + LN + P A + + V
Sbjct: 1713 GIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGP---GAGEAQGVPV 1769
Query: 1223 NVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDG 1282
VLDCDTI QAKEK+ + +E + G +L + + ++
Sbjct: 1770 KVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGL 1829
Query: 1283 ITKLNTIGHYEISNGSTIKVFKKIANF-------------TSDVEYSDD----HCHLILP 1325
+LNT+ HY++ +G+T+ + + T +E D+ HL+ P
Sbjct: 1830 WRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKP 1889
Query: 1326 DSEAFQDVQ-------GKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS 1378
E G+R R K + E+YLT+LLS K + ++ LF+ I S +
Sbjct: 1890 SDEPEPPRPRRGSLRGGERERAK---AIPEIYLTRLLSMKGTLQKFVDDLFQVILS-TSR 1945
Query: 1379 RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHI 1438
P A+KYFFD LD QA+ I+D D +HIWKTNSLPLRFW+NI+KNPQFVFD++ + ++
Sbjct: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005
Query: 1439 DGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSS 1498
D L VIAQ FMDA +L + +LG+++P NKLLYA+DIP YK V+ YY IR P S
Sbjct: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065
Query: 1499 EMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQ 1549
EM L + S + + VAL E+YKYI KY+D+I+ LE + ++ Q
Sbjct: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116
Score = 97.4 bits (241), Expect = 9e-20
Identities = 149/637 (23%), Positives = 244/637 (38%), Gaps = 102/637 (16%)
Query: 86 NCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRN 145
+C PV + +P ++ ++LLL G L++ G + +G CE R LG L +
Sbjct: 78 DCLPPVMPDECPQAQPTNNPNQLLL------VSPGALVVCG-SVHQGVCEQRRLGQLEQL 130
Query: 146 SLR----NGTEVVSCH-PQGSTAGVVYR--AGRN----NRWYLAVAATYVLPEPETASRC 194
LR T+ V+ + P ST G+V + AG R Y + +P T +
Sbjct: 131 LLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW 190
Query: 195 NPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYPYNYT 254
P D A + ++T A +GRL S HFV AF S YF + +
Sbjct: 191 PP---DPQAAFSYEET-----AKLAVGRLS----EYSHHFVSAFARGASAYFLFLRRDLQ 238
Query: 255 SGAATGWPSMARIAQSTEVLFQG-QASLDCGHGHPDGRRLLLSSSLVEALDVWAG----- 308
+ + ++R+ + + + L C G L+ ++++ + +V G
Sbjct: 239 AQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYG---LIQAAAVATSREVAHGEVLFA 295
Query: 309 VFSAAAGEGQERRSPTT------TALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPER 362
FS+AA R +ALC F + E+ A R T E ++G +
Sbjct: 296 AFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
Query: 363 VQ---------------------------PIASSTLIHS---------DLTSVYGTVVMN 386
++ P+AS + + LT+V T+
Sbjct: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
Query: 387 RTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKE 446
T+ FLG GQL +V LG + P I++ + V L D ++Y+
Sbjct: 416 HTIAFLGDSQGQLHRVYLGPGSDGH-PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQST 473
Query: 447 VRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWL---DISSGA 503
+ ++ VA+C +H C+ CL DP+CGWC L RC+ + +C + E WL G
Sbjct: 474 LLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533
Query: 504 KKCPKIQIIRSSKEKT-----TVTMVGSFSPRHSKCMVKNVDSSRELCQNKS----QPNR 554
+ + S+E+T +V + P S S L P+
Sbjct: 534 LQVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDP 593
Query: 555 TCTCSIPTRATYKDVSVV----NVMFSFGSWNLSDRFNFTNCSSLKECPACVET--GCAW 608
+ +P A Y VSV V+ + S + D T +C ACV + GC W
Sbjct: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
Query: 609 CKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGG 645
C C H +CD + + V+ + + GG
Sbjct: 654 CVWQHLCTHK-ASCDAGPMVASHQSPLVSPDPPARGG 689
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 405 bits (1042), Expect = e-112
Identities = 297/891 (33%), Positives = 436/891 (48%), Gaps = 105/891 (11%)
Query: 746 GSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDN-----LIISHELKGNINVSE- 799
G Y P+ + P +++SGG+ I + G+N DV+ ++S L+ + +
Sbjct: 1244 GQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRR 1303
Query: 800 --YCVATYCGFLAPSLKSSKVRTN------------------------VTVKLRVQDTYL 833
T C L PS S + V V+ + +
Sbjct: 1304 RRVVPETACS-LGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVF 1362
Query: 834 DCGTLQ-----YREDPRFTGYRVESEV-----DTELEVKIQKENDNFNISKKDIEITLFH 883
D TL Y DP E ++ EN + +SK+++ +
Sbjct: 1363 DFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGD 1422
Query: 884 GENGQLNCSFENITRNQ-----DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVE- 937
G C + +TR+ + L + ++ A +S + V++GNL +
Sbjct: 1423 GP-----CVVKTLTRHHLYCEPPVEQPLPRHHALREAP---DSLPEFTVQMGNLRFSLGH 1474
Query: 938 -QESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKELSR---KQSQQLELLES 986
Q S F + V LL + + V + R KSK+ R K QLE LES
Sbjct: 1475 VQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLES 1534
Query: 987 ELRKEIRDGFAELQMDKLDVV-DSFGT-VPFLDYKHFALRTFFPESGGFTHIFTEDMHNR 1044
+R + F +L + D+ D G+ +PFLDYK +A R FFP G D+
Sbjct: 1535 SVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFP--GHRESPLHRDLGVP 1592
Query: 1045 DANDKN--ESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYL 1102
++ + L L L+ +K FL IHTLE Q+ FS +DR AS LT+AL KL Y
Sbjct: 1593 ESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYF 1652
Query: 1103 TSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVT 1162
T IL L DL+ Q PKLMLRRTE+VVEKLLTNWMS+CL F+R++VGEP Y+L
Sbjct: 1653 TDILRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFR 1712
Query: 1163 TLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISV 1222
+ +++KGPVD +T KA YTLN++ LL + E+ + LN + P A + + V
Sbjct: 1713 GIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGP---GAGEAQGVPV 1769
Query: 1223 NVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDG 1282
VLDCDTI QAKEK+ + +E + G +L + + ++
Sbjct: 1770 KVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGL 1829
Query: 1283 ITKLNTIGHYEISNGSTIKVFKKIANF-------------TSDVEYSDD----HCHLILP 1325
+LNT+ HY++ +G+T+ + + T +E D+ HL+ P
Sbjct: 1830 WRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKP 1889
Query: 1326 DSEAFQDVQ-------GKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS 1378
E G+R R K + E+YLT+LLS K + ++ LF+ I S +
Sbjct: 1890 SDEPEPPRPRRGSLRGGERERAK---AIPEIYLTRLLSMKGTLQKFVDDLFQVILS-TSR 1945
Query: 1379 RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHI 1438
P A+KYFFD LD QA+ I+D D +HIWKTNSLPLRFW+NI+KNPQFVFD++ + ++
Sbjct: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005
Query: 1439 DGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSS 1498
D L VIAQ FMDA +L + +LG+++P NKLLYA+DIP YK V+ YY IR P S
Sbjct: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065
Query: 1499 EMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQ 1549
EM L + S + + VAL E+YKYI KY+D+I+ LE + ++ Q
Sbjct: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116
Score = 97.4 bits (241), Expect = 9e-20
Identities = 149/637 (23%), Positives = 244/637 (38%), Gaps = 102/637 (16%)
Query: 86 NCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRN 145
+C PV + +P ++ ++LLL G L++ G + +G CE R LG L +
Sbjct: 78 DCLPPVMPDECPQAQPTNNPNQLLL------VSPGALVVCG-SVHQGVCEQRRLGQLEQL 130
Query: 146 SLR----NGTEVVSCH-PQGSTAGVVYR--AGRN----NRWYLAVAATYVLPEPETASRC 194
LR T+ V+ + P ST G+V + AG R Y + +P T +
Sbjct: 131 LLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW 190
Query: 195 NPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYPYNYT 254
P D A + ++T A +GRL S HFV AF S YF + +
Sbjct: 191 PP---DPQAAFSYEET-----AKLAVGRLS----EYSHHFVSAFARGASAYFLFLRRDLQ 238
Query: 255 SGAATGWPSMARIAQSTEVLFQG-QASLDCGHGHPDGRRLLLSSSLVEALDVWAG----- 308
+ + ++R+ + + + L C G L+ ++++ + +V G
Sbjct: 239 AQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYG---LIQAAAVATSREVAHGEVLFA 295
Query: 309 VFSAAAGEGQERRSPTT------TALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPER 362
FS+AA R +ALC F + E+ A R T E ++G +
Sbjct: 296 AFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
Query: 363 VQ---------------------------PIASSTLIHS---------DLTSVYGTVVMN 386
++ P+AS + + LT+V T+
Sbjct: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
Query: 387 RTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKE 446
T+ FLG GQL +V LG + P I++ + V L D ++Y+
Sbjct: 416 HTIAFLGDSQGQLHRVYLGPGSDGH-PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQST 473
Query: 447 VRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWL---DISSGA 503
+ ++ VA+C +H C+ CL DP+CGWC L RC+ + +C + E WL G
Sbjct: 474 LLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533
Query: 504 KKCPKIQIIRSSKEKT-----TVTMVGSFSPRHSKCMVKNVDSSRELCQNKS----QPNR 554
+ + S+E+T +V + P S S L P+
Sbjct: 534 LQVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDP 593
Query: 555 TCTCSIPTRATYKDVSVV----NVMFSFGSWNLSDRFNFTNCSSLKECPACVET--GCAW 608
+ +P A Y VSV V+ + S + D T +C ACV + GC W
Sbjct: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
Query: 609 CKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGG 645
C C H +CD + + V+ + + GG
Sbjct: 654 CVWQHLCTHK-ASCDAGPMVASHQSPLVSPDPPARGG 689
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 404 bits (1038), Expect = e-112
Identities = 246/656 (37%), Positives = 375/656 (57%), Gaps = 54/656 (8%)
Query: 929 LGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQ---QLELLE 985
LG L + E+ L LL++ I A + + K+++ R + Q++ LE
Sbjct: 1205 LGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLE 1264
Query: 986 SELRKEIRDGFAELQMDKLDVVDSFGTV--PFLDYKHFALRTFFPESGGFTHIFTEDMHN 1043
S + E ++ FAELQ D ++ + V PFLDY+ +A+R FP G H +++
Sbjct: 1265 SRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFP--GIEAHPVLKELDT 1322
Query: 1044 RDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLT 1103
+K +L L+ +++F++T IHTLE Q +FS++DR AS +ALQ++L Y T
Sbjct: 1323 PPNVEK--ALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYAT 1380
Query: 1104 SILEVLTRDLMEQC--SNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLV 1161
+L+ L DL+E+ S PKL+LRRTESV EK+LTNW + L FL+E GEP +LL
Sbjct: 1381 GLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLY 1440
Query: 1162 TTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNIS 1221
+ Q++ KGP+D IT +A Y+L+ED L+ Q ++ T+ L+ V PENE + +
Sbjct: 1441 CAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCV---CPENEGS---AQVP 1494
Query: 1222 VNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQ--LNEIGLELQMGTRQKELLDIDSSSVIL 1279
V VL+CD+I QAK+K+ G PY + ++ LE + G + +L + + +
Sbjct: 1495 VKVLNCDSITQAKDKLLDTVYK--GIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKI 1552
Query: 1280 EDGITKLNTIGHYEISNGSTIKVFKK------IAN---FTSDVEYSDD------------ 1318
E +LN++ HY++++GS + + K +AN FT + +
Sbjct: 1553 ECDWKRLNSLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLR 1612
Query: 1319 -HCHLILPDSEAF---------QDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKL 1368
+I PD E D R + V E+YLT+LL+TK + ++ L
Sbjct: 1613 SRAPMITPDQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDL 1672
Query: 1369 FRSIWSLPN--SRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNP 1426
F +++S + S P AIKY FDFLD QA+ ++I+DPDV H WK+N LPLRFWVN++KNP
Sbjct: 1673 FETVFSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNP 1732
Query: 1427 QFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYY 1486
QFVFDI K D CLSV+AQ FMD+ S +E +LGK++P+NKLLYAKDIP YK V+ YY
Sbjct: 1733 QFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYY 1792
Query: 1487 KAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERE 1542
+ I + +S +M+ +L ++S+ H ++F+ AL E+Y Y+ KY EIL L+R+
Sbjct: 1793 RDIAKMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRD 1848
Score = 82.4 bits (202), Expect = 3e-15
Identities = 100/386 (25%), Positives = 157/386 (40%), Gaps = 70/386 (18%)
Query: 304 DVWAGVFSAAAGEGQERRS--PTTTALCLFRMSEIQARAKR-------------VSWDFK 348
DV +FS +GQ+ R+ P T LCLF +S I A +R + W
Sbjct: 315 DVLFTIFS----QGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPW-LL 369
Query: 349 TAESHCKEG-------------DQP-------ERVQPIASSTLIHSDLTSVYGTVVMNRT 388
E C +QP E + +A ST + SV +
Sbjct: 370 NKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADST---DGMASVAAYTYRQHS 426
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVR 448
V+F+GT G L KV + ++ E + + + +P+ L+ P + +IYL + K+V
Sbjct: 427 VVFIGTRSGSLKKVRVDGFQDAHLYETV-PVVDGSPILRDLLFSP-DHRHIYLLSEKQVS 484
Query: 449 RIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPK 508
++ V C +++SC+ CL + DPHCGWC RC +G C+ + + + S KC +
Sbjct: 485 QLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELS---KCVQ 541
Query: 509 IQI------IRSSKEKTTVTM--VGSFSPRHS---KCMVKN----VDSSRELCQNKS-QP 552
+++ + S + TVT+ V S S + +N + S LC + S Q
Sbjct: 542 VRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQE 601
Query: 553 NRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPACVET--GCAWCK 610
R T + V + + G F F NCS L+ C +CV + C WCK
Sbjct: 602 LRALTRG---HGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCK 658
Query: 611 SARRCI-HPFTACDPSDYERNQEQCP 635
C P + E CP
Sbjct: 659 YRHTCTSRPHECSFQEGRVHSPEGCP 684
Score = 39.3 bits (90), Expect = 0.030
Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 11/74 (14%)
Query: 460 SCSECLTATDP--HCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKC--PKI----QI 511
SC CL A DP +CGWC S RC + C + NW+ +S +C P+I +
Sbjct: 792 SCGLCLKA-DPRFNCGWCISEHRCQLRTHCPAPKT--NWMHLSQKGTRCSHPRITQIHPL 848
Query: 512 IRSSKEKTTVTMVG 525
+ + T VT+VG
Sbjct: 849 VGPKEGGTRVTIVG 862
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 384 bits (986), Expect = e-106
Identities = 249/724 (34%), Positives = 389/724 (53%), Gaps = 56/724 (7%)
Query: 863 IQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSS 922
++ E N ISK+++ + + GE C + +TR T + C+ +
Sbjct: 1195 VEGEGLNLGISKEEVRVHIGRGE-----CLVKTLTR----THLYCEPPAHAPQPANGSGL 1245
Query: 923 KKVRVKLGNLELY---VEQESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKE 972
+ V++GN++L V+ E+ P F + +L+ + + RHKSK+
Sbjct: 1246 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1305
Query: 973 LSRKQSQ---QLELLESELRKEIRDGFAELQMDKLDVVDSF--GTVPFLDYKHFALRTFF 1027
R + QLE LE+ + + R F +L + D+ +PFLDY+ +A R FF
Sbjct: 1306 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1365
Query: 1028 PESGGFTHIFTEDMHNRDAN--DKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRC 1085
P GG + D + + LT L L+ +K FL+T+IHTLE+Q +FS +DRC
Sbjct: 1366 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1425
Query: 1086 LFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCL 1145
AS L++AL KL YLT I+ L DL + PKLMLRRTE++VEKLLTNW+S+CL
Sbjct: 1426 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICL 1485
Query: 1146 SGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVF 1205
FLRE GEP Y+L + +++KGPVD +T KA TLN+ LL + EF + L V+
Sbjct: 1486 YAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLV 1545
Query: 1206 EKIPENES-ADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQ--LNEIGLELQM 1262
+ + + + VLD DTI Q KEK+ G+P+ + ++ + LE +
Sbjct: 1546 GPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYK--GTPFSQRPSVHALDLEWRS 1603
Query: 1263 GTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHL 1322
G L + + + ++ +LNT+ HY++ +G+T+ + ++ ++ + C L
Sbjct: 1604 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPL 1663
Query: 1323 -----ILPDSE-----------AFQDVQGK-------RHRGKHKFK-VKEMYLTKLLSTK 1358
L D E A ++ +G R R + K + E+YLT+LLS K
Sbjct: 1664 GENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMK 1723
Query: 1359 VAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRF 1418
+ ++ F++I S+ N P A+KY FD LD AE I DP +HIWKTNSL LRF
Sbjct: 1724 GTLQKFVDDTFQAILSV-NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRF 1782
Query: 1419 WVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTY 1478
WVN LKNPQ +FD++ + ++D L+VIAQ F+D+ + +E ++G+++P NKLLYA++IP Y
Sbjct: 1783 WVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRY 1842
Query: 1479 KEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNK 1538
K+ V+ YY IR P S EM L + S + + + AL E+Y +I +Y+D+I++
Sbjct: 1843 KQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISA 1902
Query: 1539 LERE 1542
LE +
Sbjct: 1903 LEED 1906
Score = 83.6 bits (205), Expect = 1e-15
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 51/293 (17%)
Query: 357 GDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVI 416
G QP VQP+ + +++V + FLG GQL KV L + +
Sbjct: 404 GRQPLEVQPLLK---LGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQ-----V 455
Query: 417 YEIKEETPVFYKLVPDPV---KNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCG 473
Y ++ P + PD + ++Y+ +V RI VA C + C+ CL A DP CG
Sbjct: 456 YHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCG 515
Query: 474 WCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQII----RSSKEKTTVTMVGSFSP 529
WC RCT +G C + L WL C IQ + +E+ VT+ P
Sbjct: 516 WCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLP 575
Query: 530 -----RHSKCMVKNVDSSREL------CQNKSQ------PNRTCTCSIPTRATYKDVSVV 572
+ C + DS + C Q P T ++P ++DV+V
Sbjct: 576 ILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVA 635
Query: 573 NVMFSFGSWNLSDRFNFTNCSSLK------ECPACVET--GCAWCKSARRCIH 617
+ F+F +CS+++ C ACV + C WC + C++
Sbjct: 636 -----------ATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVY 677
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 384 bits (986), Expect = e-106
Identities = 249/724 (34%), Positives = 389/724 (53%), Gaps = 56/724 (7%)
Query: 863 IQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSS 922
++ E N ISK+++ + + GE C + +TR T + C+ +
Sbjct: 1172 VEGEGLNLGISKEEVRVHIGRGE-----CLVKTLTR----THLYCEPPAHAPQPANGSGL 1222
Query: 923 KKVRVKLGNLELY---VEQESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKE 972
+ V++GN++L V+ E+ P F + +L+ + + RHKSK+
Sbjct: 1223 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1282
Query: 973 LSRKQSQ---QLELLESELRKEIRDGFAELQMDKLDVVDSF--GTVPFLDYKHFALRTFF 1027
R + QLE LE+ + + R F +L + D+ +PFLDY+ +A R FF
Sbjct: 1283 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1342
Query: 1028 PESGGFTHIFTEDMHNRDAN--DKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRC 1085
P GG + D + + LT L L+ +K FL+T+IHTLE+Q +FS +DRC
Sbjct: 1343 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1402
Query: 1086 LFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCL 1145
AS L++AL KL YLT I+ L DL + PKLMLRRTE++VEKLLTNW+S+CL
Sbjct: 1403 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICL 1462
Query: 1146 SGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVF 1205
FLRE GEP Y+L + +++KGPVD +T KA TLN+ LL + EF + L V+
Sbjct: 1463 YAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLV 1522
Query: 1206 EKIPENES-ADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQ--LNEIGLELQM 1262
+ + + + VLD DTI Q KEK+ G+P+ + ++ + LE +
Sbjct: 1523 GPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYK--GTPFSQRPSVHALDLEWRS 1580
Query: 1263 GTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHL 1322
G L + + + ++ +LNT+ HY++ +G+T+ + ++ ++ + C L
Sbjct: 1581 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPL 1640
Query: 1323 -----ILPDSE-----------AFQDVQGK-------RHRGKHKFK-VKEMYLTKLLSTK 1358
L D E A ++ +G R R + K + E+YLT+LLS K
Sbjct: 1641 GENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMK 1700
Query: 1359 VAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRF 1418
+ ++ F++I S+ N P A+KY FD LD AE I DP +HIWKTNSL LRF
Sbjct: 1701 GTLQKFVDDTFQAILSV-NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRF 1759
Query: 1419 WVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTY 1478
WVN LKNPQ +FD++ + ++D L+VIAQ F+D+ + +E ++G+++P NKLLYA++IP Y
Sbjct: 1760 WVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRY 1819
Query: 1479 KEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNK 1538
K+ V+ YY IR P S EM L + S + + + AL E+Y +I +Y+D+I++
Sbjct: 1820 KQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISA 1879
Query: 1539 LERE 1542
LE +
Sbjct: 1880 LEED 1883
Score = 83.6 bits (205), Expect = 1e-15
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 51/293 (17%)
Query: 357 GDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVI 416
G QP VQP+ + +++V + FLG GQL KV L + +
Sbjct: 381 GRQPLEVQPLLK---LGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQ-----V 432
Query: 417 YEIKEETPVFYKLVPDPV---KNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCG 473
Y ++ P + PD + ++Y+ +V RI VA C + C+ CL A DP CG
Sbjct: 433 YHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCG 492
Query: 474 WCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQII----RSSKEKTTVTMVGSFSP 529
WC RCT +G C + L WL C IQ + +E+ VT+ P
Sbjct: 493 WCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLP 552
Query: 530 -----RHSKCMVKNVDSSREL------CQNKSQ------PNRTCTCSIPTRATYKDVSVV 572
+ C + DS + C Q P T ++P ++DV+V
Sbjct: 553 ILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVA 612
Query: 573 NVMFSFGSWNLSDRFNFTNCSSLK------ECPACVET--GCAWCKSARRCIH 617
+ F+F +CS+++ C ACV + C WC + C++
Sbjct: 613 -----------ATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVY 654
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 58.2 bits (139), Expect = 6e-08
Identities = 70/252 (27%), Positives = 97/252 (38%), Gaps = 67/252 (26%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYI-------YL 441
VLFLGTGDG+L K + S P V I EE +F PV+N+ + Y
Sbjct: 463 VLFLGTGDGRLHKAV------SVGPRV--HIIEELQIFSS--GQPVQNLLLDTHRGLLYA 512
Query: 442 TAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISS 501
+ V ++ +ANC+ ++SC +CL A DP+C W S C H + L
Sbjct: 513 ASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGS--------SCKHVSLYQPQLATR- 563
Query: 502 GAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELC-QNKSQPNRTCTCSI 560
P IQ I + K + SP V + + C Q + QPN T +
Sbjct: 564 -----PWIQDIEGASAKDLCSASSVVSPSF-------VPTGEKPCEQVQFQPNTVNTLAC 611
Query: 561 P------TRATYKDVSVVNVMFS-------------------FGSWNLSDRFNFTNCSSL 595
P TR ++ + VN S F W+L + F S
Sbjct: 612 PLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQLVAS-- 669
Query: 596 KECPACVETGCA 607
CP VE G A
Sbjct: 670 -YCPEVVEDGVA 680
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 58.2 bits (139), Expect = 6e-08
Identities = 70/252 (27%), Positives = 97/252 (38%), Gaps = 67/252 (26%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYI-------YL 441
VLFLGTGDG+L K + S P V I EE +F PV+N+ + Y
Sbjct: 463 VLFLGTGDGRLHKAV------SVGPRV--HIIEELQIFSS--GQPVQNLLLDTHRGLLYA 512
Query: 442 TAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISS 501
+ V ++ +ANC+ ++SC +CL A DP+C W S C H + L
Sbjct: 513 ASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGS--------SCKHVSLYQPQLATR- 563
Query: 502 GAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELC-QNKSQPNRTCTCSI 560
P IQ I + K + SP V + + C Q + QPN T +
Sbjct: 564 -----PWIQDIEGASAKDLCSASSVVSPSF-------VPTGEKPCEQVQFQPNTVNTLAC 611
Query: 561 P------TRATYKDVSVVNVMFS-------------------FGSWNLSDRFNFTNCSSL 595
P TR ++ + VN S F W+L + F S
Sbjct: 612 PLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQLVAS-- 669
Query: 596 KECPACVETGCA 607
CP VE G A
Sbjct: 670 -YCPEVVEDGVA 680
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 57.8 bits (138), Expect = 8e-08
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 389 VLFLGTGDGQLLKVI-LGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIY---LTAG 444
VL+LGT DG L + + +G L+ + E+ +F + P PV+N+ +Y L G
Sbjct: 452 VLYLGTEDGHLHRAVRIGAQLS---------VLEDLALFPE--PQPVENMKLYHSWLLVG 500
Query: 445 K--EVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSG 502
EV ++ NC + +SCSEC+ A DP C W L C L ++ +
Sbjct: 501 SRTEVTQVNTTNCGRLQSCSECILAQDPVCAWSFRLDECVAHAG--EHRGLVQDIESADV 558
Query: 503 AKKCPK 508
+ CPK
Sbjct: 559 SSLCPK 564
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 57.8 bits (138), Expect = 8e-08
Identities = 40/113 (35%), Positives = 63/113 (55%), Gaps = 20/113 (17%)
Query: 388 TVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYI-----YLT 442
TVLF+GTGDG LLK + S P V + EE +F + +P++++ + L
Sbjct: 437 TVLFIGTGDGWLLKAV------SLGPWV--HLIEELQLFDQ---EPMRSLVLSQSKKLLF 485
Query: 443 AGKEVRRIR--VANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENL 493
AG + ++ VA+C K++SC++C+ A DP+C W + RC G HS +L
Sbjct: 486 AGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGG--HSGSL 536
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 55.5 bits (132), Expect = 4e-07
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 20/115 (17%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKE-- 446
V++LGT G L K ++ + +++ E I + P+PV+N+ + T G
Sbjct: 433 VMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPD---------PEPVRNLQLAPTQGAVFV 483
Query: 447 -----VRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENW 496
V R+ ANC+ ++SC +C+ A DPHC W + C + + NL +W
Sbjct: 484 GFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCL----LSAPNLNSW 534
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 54.7 bits (130), Expect = 7e-07
Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 19/101 (18%)
Query: 389 VLFLGTGDGQLLK-VILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYI-------Y 440
+LFLGT DG + K V+LG + I EET VF + V+N+ I Y
Sbjct: 445 LLFLGTADGWIHKAVVLGSGM---------HIIEETQVFRE--SQSVENLVISLLQHSLY 493
Query: 441 LTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRC 481
+ A V ++ +++C++++SC +C+ A DP+CGW C
Sbjct: 494 VGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHAC 534
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 18/146 (12%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDP-------VKNIYIYL 441
V+FLGT G +LKVI + S PE + + EE VF VP P VK +Y+
Sbjct: 453 VIFLGTDSGSVLKVIALQAGGSAEPEEV--VLEELQVFK--VPTPITEMEISVKRQMLYV 508
Query: 442 TAGKEVRRIRVANCNKH-KSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDIS 500
+ V ++R+ C + +C+EC A DP+C W + CT + DI
Sbjct: 509 GSRLGVAQLRLHQCETYGTACAECCLARDPYCAWDGA--SCTHYRPSLGKRRFRR-QDIR 565
Query: 501 SGAKKCPKIQIIRSSKEKTTVTMVGS 526
G P +Q + S+E+ V +V +
Sbjct: 566 HGN---PALQCLGQSQEEEAVGLVAA 588
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 50.4 bits (119), Expect = 1e-05
Identities = 33/118 (27%), Positives = 63/118 (53%), Gaps = 9/118 (7%)
Query: 376 LTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPV- 434
LTS+ + + T+ LGT +G+ ++V++ + S P V + + + PV +++ +
Sbjct: 439 LTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPST-PHVNF-LLDSHPVSPEVIVEHTL 496
Query: 435 -KNIYIYLTAGKEVRRIRV--ANCNKHKSCSECLTATD-PHCGWCHSLQRCTFQGDCV 488
+N Y + GK++ +I + C +SCS+CL+A CGWCH +C +C+
Sbjct: 497 NQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEECL 552
Score = 34.7 bits (78), Expect = 0.74
Identities = 63/257 (24%), Positives = 106/257 (41%), Gaps = 30/257 (11%)
Query: 664 IKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSL 723
I SI P+ G + + +TG N+ + N I G TC + VS+ + + +
Sbjct: 659 ITSISPKYGPMAGGTLLTLTG-NYLNSGNSRHISIGGKTCT--LKSVSNSILECYTPAQT 715
Query: 724 PSSRKEMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVID 783
S+ +K ++ D N SY P I P ++ISGG IT +G+N + +
Sbjct: 716 ISTEFAVK---LKIDLAN-RETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVS 771
Query: 784 --NLIIS-HELKGNINVSEYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQ- 839
++I+ HE N V+ C + S + N+ + L+ + ++ G L
Sbjct: 772 VPRMVINVHEAGRNFTVA--CQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSK 829
Query: 840 -----YREDPRFTGYRVESEVDTELEVKIQKENDN-FNISKKDIEITLFHGENGQL-NCS 892
Y +P F + E V I N+N I DI+ GE ++ N S
Sbjct: 830 YFDLIYVHNPVFKPF--------EKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKS 881
Query: 893 FENITRNQDLTTILCKI 909
ENI + + +LC +
Sbjct: 882 CENIHLHSE--AVLCTV 896
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 50.4 bits (119), Expect = 1e-05
Identities = 33/118 (27%), Positives = 63/118 (53%), Gaps = 9/118 (7%)
Query: 376 LTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPV- 434
LTS+ + + T+ LGT +G+ ++V++ + S P V + + + PV +++ +
Sbjct: 439 LTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPST-PHVNF-LLDSHPVSPEVIVEHTL 496
Query: 435 -KNIYIYLTAGKEVRRIRV--ANCNKHKSCSECLTATD-PHCGWCHSLQRCTFQGDCV 488
+N Y + GK++ +I + C +SCS+CL+A CGWCH +C +C+
Sbjct: 497 NQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEECL 552
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 49.3 bits (116), Expect = 3e-05
Identities = 39/139 (28%), Positives = 65/139 (46%), Gaps = 11/139 (7%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPD-----PVKNIYIYLTA 443
VLF+GT +G +LKVI N E + I EE +F VP K +Y+ +
Sbjct: 450 VLFIGTDNGIVLKVITIYNQEMESMEEV--ILEELQIFKDPVPIISMEISSKRQQLYIGS 507
Query: 444 GKEVRRIRVANCNKHKS-CSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSG 502
V ++R +C+ + S C++C A DP+C W + + H++ D+ G
Sbjct: 508 ASAVAQVRFHHCDMYGSACADCCLARDPYCAW-DGISCSRYYPTGTHAKRRFRRQDVRHG 566
Query: 503 --AKKCPKIQIIRSSKEKT 519
A++C Q + + +KT
Sbjct: 567 NAAQQCFGQQFVGDALDKT 585
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 47.8 bits (112), Expect = 8e-05
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 12/120 (10%)
Query: 371 LIHSDLTSVYGTVVMNRT---------VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKE 421
LI D+ Y +V++RT V+F+ T G L K I E+ E ++
Sbjct: 413 LIKKDVN--YTQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQL-FQD 469
Query: 422 ETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRC 481
PV L+ N ++Y + V + +A C KH +C +C+ A DP+C W C
Sbjct: 470 FEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATC 529
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 47.8 bits (112), Expect = 8e-05
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 12/120 (10%)
Query: 371 LIHSDLTSVYGTVVMNRT---------VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKE 421
LI D+ Y +V++RT V+F+ T G L K I E+ E ++
Sbjct: 413 LIKKDVN--YTQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQL-FQD 469
Query: 422 ETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRC 481
PV L+ N ++Y + V + +A C KH +C +C+ A DP+C W C
Sbjct: 470 FEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATC 529
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 45.8 bits (107), Expect = 3e-04
Identities = 33/118 (27%), Positives = 61/118 (51%), Gaps = 16/118 (13%)
Query: 371 LIHSDLTSVYGTVVMNRT--------VLFLGTGDGQLLKVI-LGENLTSNCPEVIYE--- 418
+I +D+ + +V++R V+F+GT G +LKV+ + + + EV+ E
Sbjct: 422 VIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDLEEVLLEEMT 481
Query: 419 -IKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVANCNKH-KSCSECLTATDPHCGW 474
+E T + + + +YI TAG V ++ + C+ + K+C+EC A DP+C W
Sbjct: 482 VFREPTAISAMELSTKQQQLYIGSTAG--VAQLPLHRCDIYGKACAECCLARDPYCAW 537
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 44.7 bits (104), Expect = 7e-04
Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 19/136 (13%)
Query: 361 ERVQPIASSTLIHSD---LTSVYGTVVMNRT----VLFLGTGDGQLLKVILGENLTSNCP 413
E VQP+ + D + V VV R +++L T G + KV + N TS+
Sbjct: 384 EVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTSSSC 443
Query: 414 EVIYEIKEETPVFYKLVPDPVKNIYI-------YLTAGKEVRRIRVANCNKHKSCSECLT 466
+ EE +F + +P++++ I ++ + V +I + C +++ S C+
Sbjct: 444 -----LLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIG 498
Query: 467 ATDPHCGWCHSLQRCT 482
A DP+CGW +++CT
Sbjct: 499 AQDPYCGWDVVMKKCT 514
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 44.3 bits (103), Expect = 0.001
Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 12/129 (9%)
Query: 389 VLFLGTGDGQLLKVI--LGENLTSNCPEVIYEIK--EETPVFYKLVPDPVKNIYIYLTAG 444
VL++GT G +LK + +L E ++ + P+ + + +++ L G
Sbjct: 488 VLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDG 547
Query: 445 KEVRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAK 504
V R+ + C ++S CL A DP+CGW QRC+ D S N+ W +
Sbjct: 548 --VLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRCSTLED---SSNMSLW---TQNIT 599
Query: 505 KCPKIQIIR 513
CP + R
Sbjct: 600 ACPVRNVTR 608
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 10/99 (10%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNI-----YIYLTA 443
VLFLGT G + KV++ S E+I E E VF P I +Y+++
Sbjct: 446 VLFLGTDRGTVQKVVVLPTNNSVSGELILE---ELEVFKNHAPITTMKISSKKQQLYVSS 502
Query: 444 GKEVRRIRVANCNKH-KSCSECLTATDPHCGW-CHSLQR 480
+ V ++ + C+ + +C++C A DP+C W HS R
Sbjct: 503 NEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSR 541
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 43.1 bits (100), Expect = 0.002
Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 17/111 (15%)
Query: 386 NRTVLFLGTGDGQLLKVIL-GENLTSNCPEVIYEIKEETPV--FYKLVPDPVKNIYIYLT 442
N TV+FLG+ DG +LKV+ G P ++ EI +P K + I I L
Sbjct: 437 NITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRI-IGLE 495
Query: 443 AGKEVRRIRVA-----------NCNKHKSCS-ECLTATDPHCGWCHSLQRC 481
E R+ VA C +H +C CL + DP+CGW HS + C
Sbjct: 496 LDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGW-HSSRGC 545
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 42.7 bits (99), Expect = 0.003
Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 13/94 (13%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYI-------YL 441
VLFLGT G + KVI+ L + E+ + EE VF P PVK + I Y+
Sbjct: 480 VLFLGTDRGTVQKVIV---LPKDDQELEELMLEEVEVFKD--PAPVKTMTISSKRQQLYV 534
Query: 442 TAGKEVRRIRVANCNKH-KSCSECLTATDPHCGW 474
+ V + + C + +C++C A DP+C W
Sbjct: 535 ASAVGVTHLSLHRCQAYGAACADCCLARDPYCAW 568
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 41.2 bits (95), Expect = 0.008
Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 389 VLFLGTGDGQLLKVILGENLTSNCPEVIYE---IKEETPVFYKLVPDPVKNIYIYLTAGK 445
V+FLGT G +LKV+ N EV+ E I + + + + +K +Y+ +
Sbjct: 466 VMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQIFKHSSIILNMELS-LKQQQLYIGSRD 524
Query: 446 EVRRIRVANCNKH-KSCSECLTATDPHCGW 474
+ ++ + C+ + K+C++C A DP+C W
Sbjct: 525 GLVQLSLHRCDTYGKACADCCLARDPYCAW 554
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,450,909
Number of Sequences: 37866
Number of extensions: 2748250
Number of successful extensions: 9254
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 8997
Number of HSP's gapped (non-prelim): 192
length of query: 1568
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1452
effective length of database: 13,855,062
effective search space: 20117550024
effective search space used: 20117550024
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.