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Search of human proteins with 5032131
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5032131 syntaxin 6 [Homo sapiens]
(255 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5032131 syntaxin 6 [Homo sapiens] 495 e-140
gi|4507285 syntaxin 10 [Homo sapiens] 303 1e-82
gi|4759188 syntaxin 8 [Homo sapiens] 57 1e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 50 2e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 50 2e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 50 2e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 50 2e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 44 1e-04
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 43 3e-04
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 40 0.002
gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B [... 40 0.003
gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A [... 40 0.003
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 40 0.003
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 39 0.006
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 39 0.006
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 39 0.006
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 37 0.013
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 37 0.017
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 37 0.022
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 37 0.022
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 37 0.022
gi|21735548 centrosomal protein 2 [Homo sapiens] 36 0.029
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 36 0.029
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 36 0.037
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 36 0.037
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 36 0.037
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 35 0.049
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 35 0.063
gi|40068061 centromere protein Q [Homo sapiens] 35 0.063
gi|221219020 NYD-SP11 protein [Homo sapiens] 35 0.083
>gi|5032131 syntaxin 6 [Homo sapiens]
Length = 255
Score = 495 bits (1274), Expect = e-140
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 1 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD 60
MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD
Sbjct: 1 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD 60
Query: 61 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR 120
LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR
Sbjct: 61 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR 120
Query: 121 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI 180
QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI
Sbjct: 121 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI 180
Query: 181 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI 240
GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI
Sbjct: 181 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI 240
Query: 241 LFAVLLVVLILFLVL 255
LFAVLLVVLILFLVL
Sbjct: 241 LFAVLLVVLILFLVL 255
>gi|4507285 syntaxin 10 [Homo sapiens]
Length = 249
Score = 303 bits (775), Expect = 1e-82
Identities = 155/255 (60%), Positives = 192/255 (75%), Gaps = 6/255 (2%)
Query: 1 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWD 60
MS+EDPFFVV+GEVQKAVNTA+GL+QRW ELLQ+ + REE+DWTTNELRN LRSIEWD
Sbjct: 1 MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWD 60
Query: 61 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNR 120
LEDL+ETI IVEANP KF L A +L RK F+ R+ V++MKD M + + A ER NR
Sbjct: 61 LEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNR 120
Query: 121 QALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI 180
+ L G +Q + LD A S +IEEQQA QQLI+++QD+QLE+VSGSI
Sbjct: 121 EILAGKPAAQKSPSDL------LDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSI 174
Query: 181 GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAI 240
VLK+MS R+G EL+EQ +ML+ F+ E++ TQSR+D V++KLAKVSHMTSDRRQWCAIA+
Sbjct: 175 QVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAV 234
Query: 241 LFAVLLVVLILFLVL 255
L VLL+VLIL L
Sbjct: 235 LVGVLLLVLILLFSL 249
>gi|4759188 syntaxin 8 [Homo sapiens]
Length = 236
Score = 57.4 bits (137), Expect = 1e-08
Identities = 30/99 (30%), Positives = 58/99 (58%), Gaps = 4/99 (4%)
Query: 156 EEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRL 215
+E + QQQ I+++QD L+ +S I K M Q IG EL+EQ +++D ++ +E+T +L
Sbjct: 138 DEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKL 197
Query: 216 DNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLV 254
N +++ V ++ C + ++ +LLV +++ V
Sbjct: 198 RNETRRVNMVDRKSAS----CGMIMVILLLLVAIVVVAV 232
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/232 (24%), Positives = 101/232 (43%), Gaps = 12/232 (5%)
Query: 10 VKG--EVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDET 67
+KG E K + Q + + L+D + A+R+EI T E +S+E DL L E
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELED-ARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 68 ISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDS 127
++ E ++ +L+ EL+ A S R ++D K ++ Q E + Q +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM--E 1753
Query: 128 GSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI-GVLKNM 186
+ T + +L EL S + + A+QQL E+Q+++L + G +K+
Sbjct: 1754 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGAVKSK 1811
Query: 187 SQRIGGELEEQAVMLED----FSHELESTQSRLDNVMKKLAKVSHMTSDRRQ 234
+ LE + LE+ + E ++ L KKL ++ D R+
Sbjct: 1812 FKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1863
Score = 35.4 bits (80), Expect = 0.049
Identities = 44/201 (21%), Positives = 87/201 (43%), Gaps = 33/201 (16%)
Query: 16 KAVNTAQGLFQRWTELLQ---DPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVE 72
+A+ + FQ+ E L + A ++++ T N L+ L + DL++ + +S +E
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 73 ANPRKFN-LDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN 131
RKF+ L A E +I + D +D+ +A A K +AL
Sbjct: 1448 KKQRKFDQLLAEEKNISSKY--------ADERDR-----AEAEAREKETKALS------- 1487
Query: 132 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG 191
++ EL+R N +A+ + +V +D+ V ++ L+ + +
Sbjct: 1488 -LARALEEALEAKEELERTNKML----KAEMEDLVSSKDD----VGKNVHELEKSKRALE 1538
Query: 192 GELEEQAVMLEDFSHELESTQ 212
++EE LE+ EL++T+
Sbjct: 1539 TQMEEMKTQLEELEDELQATE 1559
Score = 31.2 bits (69), Expect = 0.92
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 10/195 (5%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMST 108
EL + + ++ ++E + ++ E K D LS + Q K +ST
Sbjct: 1277 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1336
Query: 109 SSVQALAERKNRQALLGDS--GSQNWSTGTTDKYGRLD---RELQRANS--HFIEEQQAQ 161
Q ER + Q L + QN + +L ++LQ S +EE + +
Sbjct: 1337 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKR 1396
Query: 162 QQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLED---FSHELESTQSRLDNV 218
Q +E +Q E + + L+ R+ EL++ V L++ LE Q + D +
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456
Query: 219 MKKLAKVSHMTSDRR 233
+ + +S +D R
Sbjct: 1457 LAEEKNISSKYADER 1471
Score = 30.4 bits (67), Expect = 1.6
Identities = 48/241 (19%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLED-LDETIS 69
K K + +G E L D A R + + +L L +++ +LED LD T +
Sbjct: 1106 KNNALKKIRELEGHISDLQEDL-DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
Query: 70 IVEANPRKFNLDATELSIRKAFITSTRQ---VVRDMKDQMSTSSVQALAER--------- 117
E ++ + ++KA TR V++M+ Q +V+ L E+
Sbjct: 1165 QQELRAKR---EQEVTVLKKALDEETRSHEAQVQEMR-QKHAQAVEELTEQLEQFKRAKA 1220
Query: 118 ---KNRQALLGDSGSQ--------NWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLI- 165
KN+Q L ++ K +L+ ++Q S + ++A+ +L
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
Query: 166 -VEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAK 224
V + ++E V+G + + + ++ ++ + L+D L+ + NV KL +
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 225 V 225
+
Sbjct: 1341 L 1341
Score = 28.5 bits (62), Expect = 5.9
Identities = 38/200 (19%), Positives = 85/200 (42%), Gaps = 26/200 (13%)
Query: 24 LFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDAT 83
LF + LLQ TR+E +++ E +L+ E E ++ +
Sbjct: 837 LFTKVKPLLQ----VTRQE---------EEMQAKEDELQKTKERQQKAENELKELEQKHS 883
Query: 84 ELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRL 143
+L+ K + Q ++ + V+ A+++ + +L + + RL
Sbjct: 884 QLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA------------RL 931
Query: 144 DRELQRANSHFIEEQQ-AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLE 202
+ E R E ++ AQQ L +E+Q E+ E + + K ++ +LE++ ++++
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 203 DFSHELESTQSRLDNVMKKL 222
D +++L + L+ + L
Sbjct: 992 DQNNKLSKERKLLEERISDL 1011
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/232 (24%), Positives = 101/232 (43%), Gaps = 12/232 (5%)
Query: 10 VKG--EVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDET 67
+KG E K + Q + + L+D + A+R+EI T E +S+E DL L E
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELED-ARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 68 ISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDS 127
++ E ++ +L+ EL+ A S R ++D K ++ Q E + Q +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM--E 1760
Query: 128 GSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI-GVLKNM 186
+ T + +L EL S + + A+QQL E+Q+++L + G +K+
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGAVKSK 1818
Query: 187 SQRIGGELEEQAVMLED----FSHELESTQSRLDNVMKKLAKVSHMTSDRRQ 234
+ LE + LE+ + E ++ L KKL ++ D R+
Sbjct: 1819 FKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1870
Score = 35.4 bits (80), Expect = 0.049
Identities = 44/201 (21%), Positives = 87/201 (43%), Gaps = 33/201 (16%)
Query: 16 KAVNTAQGLFQRWTELLQ---DPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVE 72
+A+ + FQ+ E L + A ++++ T N L+ L + DL++ + +S +E
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 73 ANPRKFN-LDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN 131
RKF+ L A E +I + D +D+ +A A K +AL
Sbjct: 1455 KKQRKFDQLLAEEKNISSKY--------ADERDR-----AEAEAREKETKALS------- 1494
Query: 132 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG 191
++ EL+R N +A+ + +V +D+ V ++ L+ + +
Sbjct: 1495 -LARALEEALEAKEELERTNKML----KAEMEDLVSSKDD----VGKNVHELEKSKRALE 1545
Query: 192 GELEEQAVMLEDFSHELESTQ 212
++EE LE+ EL++T+
Sbjct: 1546 TQMEEMKTQLEELEDELQATE 1566
Score = 31.2 bits (69), Expect = 0.92
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 10/195 (5%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMST 108
EL + + ++ ++E + ++ E K D LS + Q K +ST
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343
Query: 109 SSVQALAERKNRQALLGDS--GSQNWSTGTTDKYGRLD---RELQRANS--HFIEEQQAQ 161
Q ER + Q L + QN + +L ++LQ S +EE + +
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKR 1403
Query: 162 QQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLED---FSHELESTQSRLDNV 218
Q +E +Q E + + L+ R+ EL++ V L++ LE Q + D +
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463
Query: 219 MKKLAKVSHMTSDRR 233
+ + +S +D R
Sbjct: 1464 LAEEKNISSKYADER 1478
Score = 30.4 bits (67), Expect = 1.6
Identities = 48/241 (19%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLED-LDETIS 69
K K + +G E L D A R + + +L L +++ +LED LD T +
Sbjct: 1113 KNNALKKIRELEGHISDLQEDL-DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1171
Query: 70 IVEANPRKFNLDATELSIRKAFITSTRQ---VVRDMKDQMSTSSVQALAER--------- 117
E ++ + ++KA TR V++M+ Q +V+ L E+
Sbjct: 1172 QQELRAKR---EQEVTVLKKALDEETRSHEAQVQEMR-QKHAQAVEELTEQLEQFKRAKA 1227
Query: 118 ---KNRQALLGDSGSQ--------NWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLI- 165
KN+Q L ++ K +L+ ++Q S + ++A+ +L
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1287
Query: 166 -VEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAK 224
V + ++E V+G + + + ++ ++ + L+D L+ + NV KL +
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 225 V 225
+
Sbjct: 1348 L 1348
Score = 28.5 bits (62), Expect = 5.9
Identities = 38/200 (19%), Positives = 85/200 (42%), Gaps = 26/200 (13%)
Query: 24 LFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDAT 83
LF + LLQ TR+E +++ E +L+ E E ++ +
Sbjct: 844 LFTKVKPLLQ----VTRQE---------EEMQAKEDELQKTKERQQKAENELKELEQKHS 890
Query: 84 ELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRL 143
+L+ K + Q ++ + V+ A+++ + +L + + RL
Sbjct: 891 QLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA------------RL 938
Query: 144 DRELQRANSHFIEEQQ-AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLE 202
+ E R E ++ AQQ L +E+Q E+ E + + K ++ +LE++ ++++
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 203 DFSHELESTQSRLDNVMKKL 222
D +++L + L+ + L
Sbjct: 999 DQNNKLSKERKLLEERISDL 1018
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/232 (24%), Positives = 101/232 (43%), Gaps = 12/232 (5%)
Query: 10 VKG--EVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDET 67
+KG E K + Q + + L+D + A+R+EI T E +S+E DL L E
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELED-ARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 68 ISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDS 127
++ E ++ +L+ EL+ A S R ++D K ++ Q E + Q +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM--E 1760
Query: 128 GSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI-GVLKNM 186
+ T + +L EL S + + A+QQL E+Q+++L + G +K+
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGAVKSK 1818
Query: 187 SQRIGGELEEQAVMLED----FSHELESTQSRLDNVMKKLAKVSHMTSDRRQ 234
+ LE + LE+ + E ++ L KKL ++ D R+
Sbjct: 1819 FKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1870
Score = 35.4 bits (80), Expect = 0.049
Identities = 44/201 (21%), Positives = 87/201 (43%), Gaps = 33/201 (16%)
Query: 16 KAVNTAQGLFQRWTELLQ---DPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVE 72
+A+ + FQ+ E L + A ++++ T N L+ L + DL++ + +S +E
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 73 ANPRKFN-LDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN 131
RKF+ L A E +I + D +D+ +A A K +AL
Sbjct: 1455 KKQRKFDQLLAEEKNISSKY--------ADERDR-----AEAEAREKETKALS------- 1494
Query: 132 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG 191
++ EL+R N +A+ + +V +D+ V ++ L+ + +
Sbjct: 1495 -LARALEEALEAKEELERTNKML----KAEMEDLVSSKDD----VGKNVHELEKSKRALE 1545
Query: 192 GELEEQAVMLEDFSHELESTQ 212
++EE LE+ EL++T+
Sbjct: 1546 TQMEEMKTQLEELEDELQATE 1566
Score = 31.2 bits (69), Expect = 0.92
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 10/195 (5%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMST 108
EL + + ++ ++E + ++ E K D LS + Q K +ST
Sbjct: 1284 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1343
Query: 109 SSVQALAERKNRQALLGDS--GSQNWSTGTTDKYGRLD---RELQRANS--HFIEEQQAQ 161
Q ER + Q L + QN + +L ++LQ S +EE + +
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKR 1403
Query: 162 QQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLED---FSHELESTQSRLDNV 218
Q +E +Q E + + L+ R+ EL++ V L++ LE Q + D +
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463
Query: 219 MKKLAKVSHMTSDRR 233
+ + +S +D R
Sbjct: 1464 LAEEKNISSKYADER 1478
Score = 30.4 bits (67), Expect = 1.6
Identities = 48/241 (19%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLED-LDETIS 69
K K + +G E L D A R + + +L L +++ +LED LD T +
Sbjct: 1113 KNNALKKIRELEGHISDLQEDL-DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1171
Query: 70 IVEANPRKFNLDATELSIRKAFITSTRQ---VVRDMKDQMSTSSVQALAER--------- 117
E ++ + ++KA TR V++M+ Q +V+ L E+
Sbjct: 1172 QQELRAKR---EQEVTVLKKALDEETRSHEAQVQEMR-QKHAQAVEELTEQLEQFKRAKA 1227
Query: 118 ---KNRQALLGDSGSQ--------NWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLI- 165
KN+Q L ++ K +L+ ++Q S + ++A+ +L
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1287
Query: 166 -VEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAK 224
V + ++E V+G + + + ++ ++ + L+D L+ + NV KL +
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 225 V 225
+
Sbjct: 1348 L 1348
Score = 28.5 bits (62), Expect = 5.9
Identities = 38/200 (19%), Positives = 85/200 (42%), Gaps = 26/200 (13%)
Query: 24 LFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDAT 83
LF + LLQ TR+E +++ E +L+ E E ++ +
Sbjct: 844 LFTKVKPLLQ----VTRQE---------EEMQAKEDELQKTKERQQKAENELKELEQKHS 890
Query: 84 ELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRL 143
+L+ K + Q ++ + V+ A+++ + +L + + RL
Sbjct: 891 QLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA------------RL 938
Query: 144 DRELQRANSHFIEEQQ-AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLE 202
+ E R E ++ AQQ L +E+Q E+ E + + K ++ +LE++ ++++
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 998
Query: 203 DFSHELESTQSRLDNVMKKL 222
D +++L + L+ + L
Sbjct: 999 DQNNKLSKERKLLEERISDL 1018
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/232 (24%), Positives = 101/232 (43%), Gaps = 12/232 (5%)
Query: 10 VKG--EVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDET 67
+KG E K + Q + + L+D + A+R+EI T E +S+E DL L E
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELED-ARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 68 ISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDS 127
++ E ++ +L+ EL+ A S R ++D K ++ Q E + Q +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM--E 1753
Query: 128 GSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSI-GVLKNM 186
+ T + +L EL S + + A+QQL E+Q+++L + G +K+
Sbjct: 1754 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGAVKSK 1811
Query: 187 SQRIGGELEEQAVMLED----FSHELESTQSRLDNVMKKLAKVSHMTSDRRQ 234
+ LE + LE+ + E ++ L KKL ++ D R+
Sbjct: 1812 FKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1863
Score = 35.4 bits (80), Expect = 0.049
Identities = 44/201 (21%), Positives = 87/201 (43%), Gaps = 33/201 (16%)
Query: 16 KAVNTAQGLFQRWTELLQ---DPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVE 72
+A+ + FQ+ E L + A ++++ T N L+ L + DL++ + +S +E
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 73 ANPRKFN-LDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQN 131
RKF+ L A E +I + D +D+ +A A K +AL
Sbjct: 1448 KKQRKFDQLLAEEKNISSKY--------ADERDR-----AEAEAREKETKALS------- 1487
Query: 132 WSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIG 191
++ EL+R N +A+ + +V +D+ V ++ L+ + +
Sbjct: 1488 -LARALEEALEAKEELERTNKML----KAEMEDLVSSKDD----VGKNVHELEKSKRALE 1538
Query: 192 GELEEQAVMLEDFSHELESTQ 212
++EE LE+ EL++T+
Sbjct: 1539 TQMEEMKTQLEELEDELQATE 1559
Score = 31.2 bits (69), Expect = 0.92
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 10/195 (5%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMST 108
EL + + ++ ++E + ++ E K D LS + Q K +ST
Sbjct: 1277 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST 1336
Query: 109 SSVQALAERKNRQALLGDS--GSQNWSTGTTDKYGRLD---RELQRANS--HFIEEQQAQ 161
Q ER + Q L + QN + +L ++LQ S +EE + +
Sbjct: 1337 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKR 1396
Query: 162 QQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLED---FSHELESTQSRLDNV 218
Q +E +Q E + + L+ R+ EL++ V L++ LE Q + D +
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456
Query: 219 MKKLAKVSHMTSDRR 233
+ + +S +D R
Sbjct: 1457 LAEEKNISSKYADER 1471
Score = 30.4 bits (67), Expect = 1.6
Identities = 48/241 (19%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLED-LDETIS 69
K K + +G E L D A R + + +L L +++ +LED LD T +
Sbjct: 1106 KNNALKKIRELEGHISDLQEDL-DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
Query: 70 IVEANPRKFNLDATELSIRKAFITSTRQ---VVRDMKDQMSTSSVQALAER--------- 117
E ++ + ++KA TR V++M+ Q +V+ L E+
Sbjct: 1165 QQELRAKR---EQEVTVLKKALDEETRSHEAQVQEMR-QKHAQAVEELTEQLEQFKRAKA 1220
Query: 118 ---KNRQALLGDSGSQ--------NWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLI- 165
KN+Q L ++ K +L+ ++Q S + ++A+ +L
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
Query: 166 -VEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAK 224
V + ++E V+G + + + ++ ++ + L+D L+ + NV KL +
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 225 V 225
+
Sbjct: 1341 L 1341
Score = 28.5 bits (62), Expect = 5.9
Identities = 38/200 (19%), Positives = 85/200 (42%), Gaps = 26/200 (13%)
Query: 24 LFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDAT 83
LF + LLQ TR+E +++ E +L+ E E ++ +
Sbjct: 837 LFTKVKPLLQ----VTRQE---------EEMQAKEDELQKTKERQQKAENELKELEQKHS 883
Query: 84 ELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRL 143
+L+ K + Q ++ + V+ A+++ + +L + + RL
Sbjct: 884 QLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA------------RL 931
Query: 144 DRELQRANSHFIEEQQ-AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLE 202
+ E R E ++ AQQ L +E+Q E+ E + + K ++ +LE++ ++++
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD 991
Query: 203 DFSHELESTQSRLDNVMKKL 222
D +++L + L+ + L
Sbjct: 992 DQNNKLSKERKLLEERISDL 1011
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 43.9 bits (102), Expect = 1e-04
Identities = 56/236 (23%), Positives = 103/236 (43%), Gaps = 24/236 (10%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISI 70
+ EV K + Q + + L++ + A+R+EI + E L+S+E ++ L E ++
Sbjct: 1640 RDEVIKQLRKLQAQMKDYQRELEE-ARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
Query: 71 VEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQ---ALAERKNRQALLGDS 127
E R + EL+ S + + D K ++ Q L E ++ LL D
Sbjct: 1699 SERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDR 1758
Query: 128 GSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLEL----VSGSI--- 180
+ TT + L+ EL S + A+QQL E+Q+++L+ + G++
Sbjct: 1759 FRK-----TTLQVDTLNAELAAERSAAQKSDNARQQL--ERQNKELKAKLQELEGAVKSK 1811
Query: 181 --GVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQ 234
+ + +I G+LEEQ LE + E + + KKL ++ D R+
Sbjct: 1812 FKATISALEAKI-GQLEEQ---LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERR 1863
Score = 38.5 bits (88), Expect = 0.006
Identities = 51/235 (21%), Positives = 96/235 (40%), Gaps = 15/235 (6%)
Query: 13 EVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVE 72
E +KA N A+ + + ++ D ++E + T EL R ++ + DL + I+ ++
Sbjct: 1018 EEEKAKNLAK-IRNKQEVMISDLEERLKKE-EKTRQELEKAKRKLDGETTDLQDQIAELQ 1075
Query: 73 ANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQA--LLGDSGSQ 130
A +D +L + K + R + + ++ + Q L D S+
Sbjct: 1076 AQ-----IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130
Query: 131 NWSTGTTDKYGR-LDRELQRANSHF---IEEQQAQQQLIVEQQDEQLELVSGSIGVLKNM 186
S +K R L EL+ + ++ AQQ+L +++ E EL KN
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH 1190
Query: 187 SQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAIL 241
+I + A LE+ S +LE + N+ K K T ++ C + +L
Sbjct: 1191 EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKN--KQGLETDNKELACEVKVL 1243
Score = 32.3 bits (72), Expect = 0.41
Identities = 39/199 (19%), Positives = 88/199 (44%), Gaps = 29/199 (14%)
Query: 26 QRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATEL 85
Q E+L D + EE + L+N + ++ ++DL+E + E +K L E
Sbjct: 918 QELEEILHDLESRVEEEEE-RNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL---EK 973
Query: 86 SIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDR 145
+A I + + ++DQ S + + E+K + + + SQ L
Sbjct: 974 VTAEAKIKKMEEEILLLEDQNS----KFIKEKKLMEDRIAECSSQ------------LAE 1017
Query: 146 ELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFS 205
E ++A + + + + +Q++++ +E+L+ + L+ +++ GE D
Sbjct: 1018 EEEKAKN--LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGE-------TTDLQ 1068
Query: 206 HELESTQSRLDNVMKKLAK 224
++ Q+++D + +LAK
Sbjct: 1069 DQIAELQAQIDELKLQLAK 1087
Score = 32.3 bits (72), Expect = 0.41
Identities = 43/223 (19%), Positives = 90/223 (40%), Gaps = 41/223 (18%)
Query: 1 MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATR---------EEIDWTTNELR 51
++++ K +V + T + L + +LL+D ++ ++++ T N L+
Sbjct: 1367 LALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ 1426
Query: 52 NNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSV 111
L + DL+ + S +E +KF+ +L + I++ RD
Sbjct: 1427 QELDDLTVDLDHQRQVASNLEKKQKKFD----QLLAEEKSISARYAEERDR--------A 1474
Query: 112 QALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQD- 170
+A A K +AL L R L+ A E ++ +QL + +D
Sbjct: 1475 EAEAREKETKAL------------------SLARALEEALEAKEEFERQNKQLRADMEDL 1516
Query: 171 -EQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQ 212
+ V ++ L+ + + ++EE LE+ EL++T+
Sbjct: 1517 MSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Score = 32.3 bits (72), Expect = 0.41
Identities = 30/182 (16%), Positives = 73/182 (40%), Gaps = 12/182 (6%)
Query: 40 REEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVV 99
+EE + +LR ++ + +D+ + + +E + R E+ + + Q
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 100 RDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQ 159
D K ++ ++QA+ + R D ++ + L+ EL E+++
Sbjct: 1559 EDAKLRLEV-NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL--------EDER 1609
Query: 160 AQQQLIV---EQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLD 216
Q+ L V ++ + L+ + I + +L + ++D+ ELE ++ D
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRD 1669
Query: 217 NV 218
+
Sbjct: 1670 EI 1671
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 42.7 bits (99), Expect = 3e-04
Identities = 56/258 (21%), Positives = 105/258 (40%), Gaps = 36/258 (13%)
Query: 10 VKGEVQKAVNTAQGLFQRWTELLQDPST--ATREEIDW-------TTNELRNNLRSIEWD 60
++G + K + + ++ + +L P+ T+EE++ T N++R+ L+SIE
Sbjct: 40 IRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQS 99
Query: 61 LEDLDETISIVEANPRKFNLDATELSIRKA-FITSTRQVVRDMKDQMSTSSVQALAERKN 119
+E N + +L IRK T +R+ V M + +T S
Sbjct: 100 IE-----------QEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQS-------DY 141
Query: 120 RQALLGDSGSQNWSTGTTDKYGRLDRELQRAN-----SHFIEEQQAQQQLIVEQQDEQLE 174
R+ G Q TG T L+ L+ N S I + +Q + E + E
Sbjct: 142 RERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSE 201
Query: 175 LV--SGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAK-VSHMTSD 231
++ SI L +M + +E Q M++ + +E ++ + K V + +
Sbjct: 202 IIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKA 261
Query: 232 RRQWCAIAILFAVLLVVL 249
RR+ I I +L +V+
Sbjct: 262 RRKKIMIIICCVILGIVI 279
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/234 (20%), Positives = 93/234 (39%), Gaps = 32/234 (13%)
Query: 30 ELLQDPSTATRE--EIDWTTNE-LRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELS 86
EL +D A E E++ NE LR N+ I +++ L + +E RKF +
Sbjct: 677 ELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFKASRDSIL 736
Query: 87 IRKAFITSTRQVVRD--MKDQMSTSSVQAL--AERKNRQALLGDSGSQNWSTGTTDKYGR 142
+ RQ M Q S S++A A R++L + G+ S + + R
Sbjct: 737 SEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKR 796
Query: 143 LD------RELQRANSHFIEEQQAQQQLI-----------------VEQQDEQLELVSGS 179
+D R+LQ+ N + E+ + +I VEQ+ +L G
Sbjct: 797 VDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQELNELRETEGG 856
Query: 180 IGVLKNMS--QRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSD 231
+ S + I +++ ED + ++ T++ + + K + + +M +
Sbjct: 857 TVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKELQKSMERWKNMEKE 910
>gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B
[Homo sapiens]
Length = 206
Score = 39.7 bits (91), Expect = 0.003
Identities = 18/58 (31%), Positives = 35/58 (60%)
Query: 168 QQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKV 225
+ DE LE VSG IG L++M+ +G E++ Q ++ + +S ++R+D ++ K+
Sbjct: 145 EMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKM 202
>gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A
[Homo sapiens]
Length = 206
Score = 39.7 bits (91), Expect = 0.003
Identities = 18/58 (31%), Positives = 35/58 (60%)
Query: 168 QQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKV 225
+ DE LE VSG IG L++M+ +G E++ Q ++ + +S ++R+D ++ K+
Sbjct: 145 EMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKM 202
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/206 (20%), Positives = 83/206 (40%), Gaps = 25/206 (12%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISI 70
K E+Q+A++ A +W + + EE++ +L L+ E +E ++ +
Sbjct: 1355 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS 1414
Query: 71 VEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQ 130
+E ++ + +L M D +S+ A ++K R D
Sbjct: 1415 LEKTKQRLQGEVEDL----------------MVDVERANSLAAALDKKQRNF---DKVLA 1455
Query: 131 NWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRI 190
W T + L+ L+ + S + + + + E+ +QLE V KN+ Q I
Sbjct: 1456 EWKTKCEESQAELEASLKESRS--LSTELFKLKNAYEEALDQLETVKRE---NKNLEQEI 1510
Query: 191 GGELEEQAVMLEDFSHELESTQSRLD 216
+L EQ HELE ++ +++
Sbjct: 1511 -ADLTEQIAENGKTIHELEKSRKQIE 1535
Score = 37.0 bits (84), Expect = 0.017
Identities = 47/227 (20%), Positives = 95/227 (41%), Gaps = 32/227 (14%)
Query: 16 KAVNTAQGLFQRWTELLQDPSTATR---EEIDWTTNELRNNLRSIEWDLEDLDETISIVE 72
++V+ ++ ++ L+D + R EEI + +EL ++ + +L + E
Sbjct: 1237 ESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKE 1296
Query: 73 ANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNW 132
+ + + ++AF T ++ R ++++ + A A + +R D + +
Sbjct: 1297 SIVSQLSRS------KQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDC--DLLREQY 1348
Query: 133 STGTTDKYGRLDRELQRANSHFI---------------EEQQAQQQLIVEQQD--EQLEL 175
K L R L +ANS E ++A+++L QD EQ+E
Sbjct: 1349 EEEQEGK-AELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEA 1407
Query: 176 VSGSIGVLKNMSQRIGGELEEQAVMLE---DFSHELESTQSRLDNVM 219
V+ L+ QR+ GE+E+ V +E + L+ Q D V+
Sbjct: 1408 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVL 1454
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 38.5 bits (88), Expect = 0.006
Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 22/146 (15%)
Query: 96 RQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFI 155
RQ V+ +K+Q++ +K ++ G SG+Q+ + G T+ G E RA +
Sbjct: 1084 RQTVKQLKEQLA---------KKEKEHASG-SGAQSEAAGRTEPTGP-KLEALRAEVSKL 1132
Query: 156 EEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRL 215
E+Q +QQ + + LE S + + + G+LEE+A EL +QS L
Sbjct: 1133 EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKA-------QELGHSQSAL 1185
Query: 216 DNVMKKLA----KVSHMTSDRRQWCA 237
+ ++LA KV + +W A
Sbjct: 1186 ASAQRELAAFRTKVQDHSKAEDEWKA 1211
Score = 32.0 bits (71), Expect = 0.54
Identities = 36/173 (20%), Positives = 76/173 (43%), Gaps = 9/173 (5%)
Query: 62 EDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQ 121
+ L + +E R+ ELS + A +V + + ++ E + Q
Sbjct: 1531 QKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQ 1590
Query: 122 ALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIG 181
A L + +Q ++ +L ++++A +H+ ++Q Q+L ++Q LE +
Sbjct: 1591 AQLNELQAQLSQKEQAAEHYKL--QMEKAKTHYDAKKQQNQEL--QEQLRSLEQLQKENK 1646
Query: 182 VLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKL-AKVSHMTSDRR 233
L+ ++R+G EL++ + + E E T L ++ L A+V+H R
Sbjct: 1647 ELRAEAERLGHELQQAGLK----TKEAEQTCRHLTAQVRSLEAQVAHADQQLR 1695
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 38.5 bits (88), Expect = 0.006
Identities = 42/216 (19%), Positives = 91/216 (42%), Gaps = 12/216 (5%)
Query: 15 QKAVNTAQGLF---QRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIV 71
++ + +A+GL Q E LQ+ T++ + T + L N +E + + +ETI+ +
Sbjct: 443 EQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAM 502
Query: 72 EANPR-KFNLDATELSIR-----KAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLG 125
+ + K + A +L I+ + + R+ +R ++ S++ L + K+R+
Sbjct: 503 KEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREK--- 559
Query: 126 DSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKN 185
++ +W D ++ Q + Q + QQL + E+ L + +
Sbjct: 560 NAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQ 619
Query: 186 MSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKK 221
QR E + + E E Q L+N +++
Sbjct: 620 HQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQ 655
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 38.5 bits (88), Expect = 0.006
Identities = 42/216 (19%), Positives = 91/216 (42%), Gaps = 12/216 (5%)
Query: 15 QKAVNTAQGLF---QRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIV 71
++ + +A+GL Q E LQ+ T++ + T + L N +E + + +ETI+ +
Sbjct: 563 EQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAM 622
Query: 72 EANPR-KFNLDATELSIR-----KAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLG 125
+ + K + A +L I+ + + R+ +R ++ S++ L + K+R+
Sbjct: 623 KEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREK--- 679
Query: 126 DSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKN 185
++ +W D ++ Q + Q + QQL + E+ L + +
Sbjct: 680 NAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQ 739
Query: 186 MSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKK 221
QR E + + E E Q L+N +++
Sbjct: 740 HQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQ 775
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 37.4 bits (85), Expect = 0.013
Identities = 42/193 (21%), Positives = 90/193 (46%), Gaps = 15/193 (7%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVE--ANPRKFNLDATELSIRKAFITSTRQVVRDMKDQM 106
+ +N L+ E + + L I+ ++ + +K ++A + ++ A + T + + Q
Sbjct: 942 QAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTE--LENKLQQQ 999
Query: 107 STSSVQALAERKNRQALLGDSGSQNWSTGT---TDKYGRLDRELQ-RANSHFIEEQQ--A 160
T + Q LA K + ++L ++ ++ T +D YGR L R + +EE+ A
Sbjct: 1000 LTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLA 1059
Query: 161 QQQLI-----VEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRL 215
Q+ LI + Q++ ++ + + L+ S + +L+E+ L+D E + L
Sbjct: 1060 QEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKEL 1119
Query: 216 DNVMKKLAKVSHM 228
N KLA++ +
Sbjct: 1120 VNEKSKLAEIEEI 1132
Score = 35.8 bits (81), Expect = 0.037
Identities = 32/187 (17%), Positives = 86/187 (45%), Gaps = 7/187 (3%)
Query: 38 ATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQ 97
AT + D +L++ L + E L + +S +K + +E+ + + + +
Sbjct: 337 ATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFK 396
Query: 98 VVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEE 157
++ +++ +Q +E + L ++ Q + +GRL + Q ++ +++
Sbjct: 397 QLQQQREEKEQHGLQLQSEINQLHSKLLETERQ-----LGEAHGRLKEQRQLSSEKLMDK 451
Query: 158 QQ--AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRL 215
+Q A QL + + +EQL+ + L++ + + +EQ + + + +L Q+ L
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511
Query: 216 DNVMKKL 222
+ V++++
Sbjct: 512 EQVLRQI 518
Score = 28.1 bits (61), Expect = 7.8
Identities = 43/239 (17%), Positives = 96/239 (40%), Gaps = 45/239 (18%)
Query: 13 EVQKAVNTAQGLFQRWT------ELLQDPSTATREEIDWTTNELRNNLRSIEWDLED--L 64
++QK + + Q+ T ++L+ +E EL N +++ +L+ +
Sbjct: 787 DLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKM 846
Query: 65 DETISIVEANPRKFNLDATELSIR-------------KAFITSTRQVVRDMKDQMSTSSV 111
++ + E + K L S++ KA I + +++K Q+
Sbjct: 847 EKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQME 906
Query: 112 QALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDE 171
L E+K + L +K +L + + ++EQ Q Q ++Q ++
Sbjct: 907 NTLKEQKELKKSL-------------EKEKEASHQL-KLELNSMQEQLIQAQNTLKQNEK 952
Query: 172 QLELVSGSIGVLKNMSQR-------IGGELEEQAVMLEDFSHELESTQSRLDNVMKKLA 223
+ + + G+I LK S++ + GEL+ + + ++L Q +L ++LA
Sbjct: 953 EEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKL---QQQLTQAAQELA 1008
>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
Length = 388
Score = 37.0 bits (84), Expect = 0.017
Identities = 43/196 (21%), Positives = 80/196 (40%), Gaps = 44/196 (22%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVEANP----RKFNLDATELSIRKAFITSTRQVVRDMKD 104
E ++L + + + L E +++ E R+ NL EL I K + TR+ V +K+
Sbjct: 5 EKEDSLMTCQQIYKALQEELTVKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKN 64
Query: 105 QMS------TSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQ 158
+ S++ L E RQ LL D NW +++ EL + + + E
Sbjct: 65 ERELMLISHQKSIEQLQETL-RQKLLSD---DNWKE-------KIEAELAKERAQHLVEF 113
Query: 159 QAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNV 218
+ Q L E+ QL++ E E+ +++ + E E Q ++ ++
Sbjct: 114 EEQALLFKEETKLQLDI-----------------EKEKHQDVIQKYKKEQEELQMKISDL 156
Query: 219 MKKLAKVSHMTSDRRQ 234
++ T D RQ
Sbjct: 157 ------ITGATRDLRQ 166
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 36.6 bits (83), Expect = 0.022
Identities = 47/207 (22%), Positives = 86/207 (41%), Gaps = 44/207 (21%)
Query: 33 QDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFI 92
+D S+ + E+D L L+ +E + D D+ I+ +E + N L ++
Sbjct: 748 KDESSKAQAEVD----RLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE--- 800
Query: 93 TSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANS 152
QV + S Q L E + R+ L DS Q D + D ++
Sbjct: 801 ----QVEKK-------KSAQMLEEARRREDNLNDSSQQ-----LQDSLRKKDDRIEELEE 844
Query: 153 HFIEEQQ--AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGE--LEEQAVMLEDFSHEL 208
E Q A++++++ Q++ S R E +EE + +E EL
Sbjct: 845 ALRESVQITAEREMVLAQEE----------------SARTNAEKQVEELLMAMEKVKQEL 888
Query: 209 ESTQSRLDNVMKKLA-KVSHMTSDRRQ 234
ES +++L + + LA K +H+T+ R +
Sbjct: 889 ESMKAKLSSTQQSLAEKETHLTNLRAE 915
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 36.6 bits (83), Expect = 0.022
Identities = 47/207 (22%), Positives = 86/207 (41%), Gaps = 44/207 (21%)
Query: 33 QDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFI 92
+D S+ + E+D L L+ +E + D D+ I+ +E + N L ++
Sbjct: 720 KDESSKAQAEVD----RLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE--- 772
Query: 93 TSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANS 152
QV + S Q L E + R+ L DS Q D + D ++
Sbjct: 773 ----QVEKK-------KSAQMLEEARRREDNLNDSSQQ-----LQDSLRKKDDRIEELEE 816
Query: 153 HFIEEQQ--AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGE--LEEQAVMLEDFSHEL 208
E Q A++++++ Q++ S R E +EE + +E EL
Sbjct: 817 ALRESVQITAEREMVLAQEE----------------SARTNAEKQVEELLMAMEKVKQEL 860
Query: 209 ESTQSRLDNVMKKLA-KVSHMTSDRRQ 234
ES +++L + + LA K +H+T+ R +
Sbjct: 861 ESMKAKLSSTQQSLAEKETHLTNLRAE 887
>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
sapiens]
Length = 805
Score = 36.6 bits (83), Expect = 0.022
Identities = 38/197 (19%), Positives = 84/197 (42%), Gaps = 12/197 (6%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMST 108
E + + ++E L DL + + + L+ ++++A I T + + ++K Q
Sbjct: 503 EKQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALI-DTEKKLEEIKKQCQD 561
Query: 109 SSVQALAERKNRQALLGDSGSQNWSTGTTDKYG----RLD-RELQRANSHFIEEQQAQQQ 163
Q + ++K + L+ S + G LD ++LQ N + ++ + +
Sbjct: 562 KETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQLQNENDNLRQQNETASK 621
Query: 164 LIVEQQDE------QLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDN 217
+I QQDE +++ + G + K +Q++ ELE++ ++ + L Q + D
Sbjct: 622 IIDSQQDEIDRMILEIQSMQGKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDE 681
Query: 218 VMKKLAKVSHMTSDRRQ 234
L + R+Q
Sbjct: 682 TCSLLDQGQEPDQSRQQ 698
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 36.2 bits (82), Expect = 0.029
Identities = 45/236 (19%), Positives = 102/236 (43%), Gaps = 20/236 (8%)
Query: 9 VVKGEVQKA----VNTAQGLFQRWTEL--LQDPSTATREEIDWTTNELRNNLRSIEWDLE 62
V++ +VQK +T Q TEL LQ + +EE ++ S+E +L
Sbjct: 1261 VLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEE----KSKWEGKQNSLESELM 1316
Query: 63 DLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQA 122
+L ET++ +++ R+ L E + + + ++ + + + + V+A A+
Sbjct: 1317 ELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGI 1376
Query: 123 LLGDSGSQNWSTGTTDKYGRLDR----------ELQRANSHFIEEQQAQQQLIVEQQDEQ 172
L D + + ++ +R EL+ A ++E A + +++E+
Sbjct: 1377 LEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEE 1436
Query: 173 LELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHM 228
+E + G I L+ + LE ++ L+ + E++ Q ++ + K + + H+
Sbjct: 1437 VETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHL 1492
Score = 30.8 bits (68), Expect = 1.2
Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 15/117 (12%)
Query: 99 VRDMKDQM-STSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHF-IE 156
V D+K Q+ + Q L E++ ++ L T +Y R+ +EL+R + +
Sbjct: 1012 VEDLKSQLVAQDDSQRLVEQEVQEKLR-----------ETQEYNRIQKELEREKASLTLS 1060
Query: 157 EQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQS 213
+ +Q+L+V Q+ + + + L+ Q GE +E + +E E++ ++
Sbjct: 1061 LMEKEQRLLVLQEADSIR--QQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEA 1115
Score = 28.5 bits (62), Expect = 5.9
Identities = 40/208 (19%), Positives = 83/208 (39%), Gaps = 28/208 (13%)
Query: 16 KAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANP 75
+ + T + L Q E + PS A R ++ LR+ + +E E + E + +
Sbjct: 1697 RELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLE 1756
Query: 76 RKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTG 135
++ ++ ++ Q + ++ Q+ + Q + ++ Q+ L
Sbjct: 1757 QQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLD---------- 1806
Query: 136 TTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELE 195
E QRA + +E +A QQ EQQ Q G +K + + G LE
Sbjct: 1807 ----------EAQRALAQRDQELEALQQ---EQQQAQ-----GQEERVKEKADALQGALE 1848
Query: 196 EQAVMLEDFSHELESTQSRLDNVMKKLA 223
+ + L++ EL+ + + + ++LA
Sbjct: 1849 QAHMTLKERHGELQDHKEQARRLEEELA 1876
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 36.2 bits (82), Expect = 0.029
Identities = 44/237 (18%), Positives = 98/237 (41%), Gaps = 16/237 (6%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISI 70
+ E+Q+ ++ A +W + + EE++ +L L+ E +E + S
Sbjct: 1403 QAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSS 1462
Query: 71 VEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGD--SG 128
+E + ++ ++++ TS + D+ +AL ER+ ++ +
Sbjct: 1463 LEKAKLRLQTESEDVTLELERATSAAAAL----DKKQRHLERALEERRRQEEEMQRELEA 1518
Query: 129 SQNWSTGTTDKYGRL----DRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLK 184
+Q S G + RL + L+ + E + Q++ + +Q+ L SI L+
Sbjct: 1519 AQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEE--ISDLTDQVSLSGKSIQELE 1576
Query: 185 NMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKL----AKVSHMTSDRRQWCA 237
+ + GE E LE+ LE +++ + +L A+V +++ + CA
Sbjct: 1577 KTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECA 1633
Score = 29.6 bits (65), Expect = 2.7
Identities = 36/182 (19%), Positives = 76/182 (41%), Gaps = 22/182 (12%)
Query: 49 ELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMST 108
+L ++ + LED +E + + A RK + TEL ++ + D+K ++
Sbjct: 963 QLEGKVKELSERLEDEEEVNADLAARRRKLEDECTEL----------KKDIDDLKLTLAK 1012
Query: 109 SSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQ------ 162
+ + A + L + + + S K + LQ A+ + + QA++
Sbjct: 1013 AEKEKQATENKVKNLTEEMAALDESVARLTKE---KKALQEAHQQALGDLQAEEDRVSAL 1069
Query: 163 ---QLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVM 219
+L +EQQ E LE L+ ++R +LE + ++ + + +L+ +
Sbjct: 1070 TKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKL 1129
Query: 220 KK 221
KK
Sbjct: 1130 KK 1131
Score = 28.1 bits (61), Expect = 7.8
Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
Query: 156 EEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFS-------HEL 208
E+Q ++ ++ VE+ QL S G L+ S + LEE+ ++ S L
Sbjct: 1302 EDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSL 1361
Query: 209 ESTQSRLDNVMKKLAKVSHMTSDRRQWC 236
E + +L+ K + ++H R C
Sbjct: 1362 EELRRQLEEESKAKSALAHAVQALRHDC 1389
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 35.8 bits (81), Expect = 0.037
Identities = 36/178 (20%), Positives = 76/178 (42%), Gaps = 6/178 (3%)
Query: 61 LEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKN- 119
LE +++ + + +K D EL + RQ + ++ S S + L +N
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQ 371
Query: 120 --RQALLGDSGSQNWST--GTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLEL 175
+ L + S+ +T +K+ R D++ + E ++ + + ++Q+ ++E
Sbjct: 372 VKKYHRLKEEASKRAATLAQELEKFNR-DQKADQDRLDLEERKKVETEAKIKQKLREIEE 430
Query: 176 VSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRR 233
I L+ LEEQ + + + E+E + R+D + K+L +V D R
Sbjct: 431 NQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDAR 488
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 35.8 bits (81), Expect = 0.037
Identities = 38/217 (17%), Positives = 86/217 (39%), Gaps = 4/217 (1%)
Query: 11 KGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISI 70
K E+Q+ ++ A +W + + EE++ +L L+ E +E ++ +
Sbjct: 1358 KAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCAS 1417
Query: 71 VEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQ 130
+E ++ + +L I S + K Q + V A ++K + SQ
Sbjct: 1418 LEKTKQRLQNEVEDLMIDVE--RSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQ 1475
Query: 131 NWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGS--IGVLKNMSQ 188
S + + ++ + + H ++ + L E D ++ G I L+ + +
Sbjct: 1476 KESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKK 1535
Query: 189 RIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKV 225
++ E E LE+ LE + ++ + +L +V
Sbjct: 1536 QLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQV 1572
Score = 28.5 bits (62), Expect = 5.9
Identities = 46/249 (18%), Positives = 96/249 (38%), Gaps = 36/249 (14%)
Query: 13 EVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISI-V 71
++QK + Q + E ++ A+R + + ++L L I LE+ S +
Sbjct: 1107 QLQKKIKELQARIEELEEEIE-AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
Query: 72 EANPRK---------------FNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAE 116
E N ++ +AT ++RK S ++ + Q L +
Sbjct: 1166 EMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVK--QKLEK 1223
Query: 117 RKNRQALLGDSGSQNWSTGTTDK--YGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLE 174
K+ + + + N T + K + ++ R L+ S +++ QQ+LI E
Sbjct: 1224 EKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINE------- 1276
Query: 175 LVSGSIGVLKNMSQRIGGELEEQAVML-------EDFSHELESTQSRLDNVMKKLAKVSH 227
+S L S +L+E+ M+ + F+ ++E + +L+ K + ++H
Sbjct: 1277 -LSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAH 1335
Query: 228 MTSDRRQWC 236
R C
Sbjct: 1336 ALQSARHDC 1344
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 35.8 bits (81), Expect = 0.037
Identities = 47/242 (19%), Positives = 97/242 (40%), Gaps = 12/242 (4%)
Query: 2 SMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQD---PSTATREEIDWTTNELRNNLRSIE 58
SM P V E ++ Q + Q L Q+ S E+ D + + N R +E
Sbjct: 548 SMLIPSMSVTMETSMIMSNIQRIIQENERLKQEILEKSNRIEEQNDKISELIERNQRYVE 607
Query: 59 WD---LEDLDETISIVEANP--RKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQA 113
+E + ++ N R + + + + + +T QV + +
Sbjct: 608 QSNLMMEKRNNSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKET 667
Query: 114 LAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQL---IVEQQD 170
+ + ++L + T K L ++A S F E+Q ++QL + ++
Sbjct: 668 ELQMQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEE 727
Query: 171 EQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTS 230
E +L + KN+S+R +E++ E+ +S Q LD +++L K + +++
Sbjct: 728 ELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDK-LRQLLKKTRVST 786
Query: 231 DR 232
D+
Sbjct: 787 DQ 788
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 35.4 bits (80), Expect = 0.049
Identities = 31/143 (21%), Positives = 62/143 (43%), Gaps = 5/143 (3%)
Query: 33 QDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFI 92
Q S +E+ T N+ +S+E +E+L +T+S E R +L ++ +
Sbjct: 1469 QHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQL---QSEL 1525
Query: 93 TSTRQVVRDMKDQMSTSSVQAL-AERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRAN 151
+ RQ ++D Q Q E K R+A++ G D+ + + EL++ N
Sbjct: 1526 SRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRN 1585
Query: 152 SHFIEEQQAQQQLIVEQQDEQLE 174
+++Q+ + + + Q E
Sbjct: 1586 G-ALDQQKDELDVRITALKSQYE 1607
Score = 30.8 bits (68), Expect = 1.2
Identities = 33/170 (19%), Positives = 67/170 (39%), Gaps = 29/170 (17%)
Query: 24 LFQRWTELLQDPSTATREEIDWTT----------------NELRNNLRSIEWDLEDLDET 67
L +R + LQD A RE++ T N + + + + E L++
Sbjct: 1230 LLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQD 1289
Query: 68 ISIVEANPRKFNLDA-------TELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKN- 119
+ ++A RK LD ELS + + + ++++ + + + ++++K+
Sbjct: 1290 LQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDP 1349
Query: 120 -----RQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQL 164
R+ L T++ GRL E+ R+N+ Q Q L
Sbjct: 1350 DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSL 1399
Score = 30.4 bits (67), Expect = 1.6
Identities = 32/196 (16%), Positives = 77/196 (39%), Gaps = 2/196 (1%)
Query: 40 REEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVV 99
+ EI + L NN I+ EDL++ + E + + ++ + IT +++
Sbjct: 1379 KAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIG 1438
Query: 100 RDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQ 159
R K Q Q + GD Q+ S + + + + + +
Sbjct: 1439 RRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVE 1498
Query: 160 AQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHEL-ESTQSRLDNV 218
Q+ + E++ E L ++ + +S R+ +L+++ E ++ E + +
Sbjct: 1499 NLQKTLSEKETEARNLQEQTVQLQSELS-RLRQDLQDRTTQEEQLRQQITEKEEKTRKAI 1557
Query: 219 MKKLAKVSHMTSDRRQ 234
+ +K++H+ + Q
Sbjct: 1558 VAAKSKIAHLAGVKDQ 1573
Score = 30.0 bits (66), Expect = 2.0
Identities = 43/230 (18%), Positives = 89/230 (38%), Gaps = 36/230 (15%)
Query: 13 EVQKAVNTAQGLFQRWTEL---------LQDPSTATREEIDWTTNELRNNLRSIEWDLED 63
E++K N + L ++ EL +Q T T+EE++ +L + +LE
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEY 140
Query: 64 LDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQAL 123
L E + + ++ N EL ++ D++ S V K +
Sbjct: 141 LTEDVKRLNEKLKESNTTKGELQLK--------------LDELQASDVSVKYREKRLEQE 186
Query: 124 LGDSGSQNWSTGT-----TDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSG 178
SQN T TD+ L RE + N + + + +E + E++ +
Sbjct: 187 KELLHSQNTWLNTELKTKTDELLALGRE--KGN------EILELKCNLENKKEEVSRLEE 238
Query: 179 SIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHM 228
+ LK ++ + +E+ L++ + S + + N + K+S++
Sbjct: 239 QMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNL 288
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 35.0 bits (79), Expect = 0.063
Identities = 34/190 (17%), Positives = 82/190 (43%), Gaps = 24/190 (12%)
Query: 30 ELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRK 89
E LQ+ T R E+++ EL+ ++ L+ +E + N RK ++ +
Sbjct: 563 ENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCN----NLRK------QVENKN 612
Query: 90 AFITSTRQVVRDMKDQMSTSSVQ--ALAERKNRQALLGDSGSQNWSTGTTDKYGRLDREL 147
+I +Q + +K + + S Q + N+ L +S Q K+G +
Sbjct: 613 KYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQ--------KFGEITDTY 664
Query: 148 QRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHE 207
Q+ IE+++ ++ ++E+ ++ + ++ + K + +R ++ E ++E H+
Sbjct: 665 QKE----IEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQ 720
Query: 208 LESTQSRLDN 217
+ D+
Sbjct: 721 YDKIIEERDS 730
>gi|40068061 centromere protein Q [Homo sapiens]
Length = 268
Score = 35.0 bits (79), Expect = 0.063
Identities = 41/182 (22%), Positives = 78/182 (42%), Gaps = 12/182 (6%)
Query: 41 EEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVR 100
EE+ + N++RN ++ + L+DL N + A++ + STR ++
Sbjct: 26 EEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQ 85
Query: 101 DMKDQM-STSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRE----------LQR 149
M + + T ++ E++ Q L + T K E ++R
Sbjct: 86 TMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMER 145
Query: 150 ANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELE 209
A EE A Q +++ E EL++G+I LKN Q + E+EE+ ++ H++
Sbjct: 146 ARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQM-HQIN 204
Query: 210 ST 211
S+
Sbjct: 205 SS 206
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 34.7 bits (78), Expect = 0.083
Identities = 43/235 (18%), Positives = 93/235 (39%), Gaps = 37/235 (15%)
Query: 41 EEIDWTTNELRNNLRSIEWDLEDL--------DETISIVEANPR-------------KFN 79
+ +DW EL L +EWD+E+L E +VE + K +
Sbjct: 1705 QNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLS 1764
Query: 80 LDATELSIRKAFITSTRQVVRDMKDQMSTSSV------QALAERKNRQALLGDSGSQNWS 133
+ T+L+ + + ++ + K++M + L E+K + A + +
Sbjct: 1765 EEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSME 1824
Query: 134 TGTTDK---YGRLDRELQRANSHFIEEQQAQ--QQLIVEQQ-----DEQLELVSGSIGVL 183
T +K Y + + ++ N +E+ AQ + L+ ++ +QL V +G+
Sbjct: 1825 ELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMF 1884
Query: 184 KNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAI 238
+ ++ +L ++ + +L T+ +L V LAK + + A+
Sbjct: 1885 NKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLAL 1939
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,686,776
Number of Sequences: 37866
Number of extensions: 297362
Number of successful extensions: 2592
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 2173
Number of HSP's gapped (non-prelim): 596
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.