Search of human proteins with 5031943

Search of human proteins with 5031943

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031943 nescient helix loop helix 1 [Homo sapiens]
         (133 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031943 nescient helix loop helix 1 [Homo sapiens]                 274   2e-74
gi|161484632 nescient helix loop helix 2 [Homo sapiens]               145   9e-36
gi|5031945 nescient helix loop helix 2 [Homo sapiens]                 145   9e-36
gi|4507741 twist [Homo sapiens]                                        70   5e-13
gi|148922889 scleraxis homolog B [Homo sapiens]                        67   5e-12
gi|186972126 scleraxis homolog A [Homo sapiens]                        67   5e-12
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    66   7e-12
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    65   1e-11
gi|239749439 PREDICTED: similar to transcription factor 23 [Homo...    65   2e-11
gi|239743573 PREDICTED: similar to transcription factor 23 [Homo...    65   2e-11
gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho...    63   6e-11
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    63   8e-11
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          63   8e-11
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]          62   1e-10
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    61   2e-10
gi|116805332 musculin [Homo sapiens]                                   60   7e-10
gi|17981708 twist homolog 2 [Homo sapiens]                             59   9e-10
gi|38202237 transcription factor 21 [Homo sapiens]                     59   9e-10
gi|38202239 transcription factor 21 [Homo sapiens]                     59   9e-10
gi|239754900 PREDICTED: similar to transcription factor 23 [Homo...    59   1e-09
gi|23097242 nephew of atonal 3 [Homo sapiens]                          55   1e-08
gi|31077092 neurogenin 2 [Homo sapiens]                                55   2e-08
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    54   5e-08
gi|21553337 atonal homolog 7 [Homo sapiens]                            52   2e-07
gi|68989258 neurogenin 3 [Homo sapiens]                                51   2e-07
gi|75677394 transcription factor 23 [Homo sapiens]                     51   2e-07
gi|38455396 neurogenin 1 [Homo sapiens]                                50   4e-07
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]                50   7e-07
gi|55743094 achaete-scute complex homolog 1 [Homo sapiens]             49   9e-07
gi|27475985 neurogenic differentiation 6 [Homo sapiens]                49   1e-06

>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
          Length = 133

 Score =  274 bits (700), Expect = 2e-74
 Identities = 133/133 (100%), Positives = 133/133 (100%)

Query: 1   MMLNSDTMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQH 60
           MMLNSDTMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQH
Sbjct: 1   MMLNSDTMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQH 60

Query: 61  LSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA 120
           LSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA
Sbjct: 61  LSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA 120

Query: 121 ICYISYLNHVLDV 133
           ICYISYLNHVLDV
Sbjct: 121 ICYISYLNHVLDV 133


>gi|161484632 nescient helix loop helix 2 [Homo sapiens]
          Length = 135

 Score =  145 bits (366), Expect = 9e-36
 Identities = 78/101 (77%), Positives = 81/101 (80%), Gaps = 8/101 (7%)

Query: 33  DGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFN 92
           +  G G  G   A  P P        Q LSREE+RRRRRATAKYR+AHATRERIRVEAFN
Sbjct: 43  EAEGDGKGGSRAALYPHP--------QQLSREEKRRRRRATAKYRSAHATRERIRVEAFN 94

Query: 93  LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 133
           LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
Sbjct: 95  LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 135


>gi|5031945 nescient helix loop helix 2 [Homo sapiens]
          Length = 135

 Score =  145 bits (366), Expect = 9e-36
 Identities = 78/101 (77%), Positives = 81/101 (80%), Gaps = 8/101 (7%)

Query: 33  DGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFN 92
           +  G G  G   A  P P        Q LSREE+RRRRRATAKYR+AHATRERIRVEAFN
Sbjct: 43  EAEGDGKGGSRAALYPHP--------QQLSREEKRRRRRATAKYRSAHATRERIRVEAFN 94

Query: 93  LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 133
           LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
Sbjct: 95  LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 135


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 70.1 bits (170), Expect = 5e-13
 Identities = 49/118 (41%), Positives = 59/118 (50%), Gaps = 14/118 (11%)

Query: 27  GGGAGPDGAGPGGPGGGQARG-PEPGEPGRKDL------------QHLSREERRRRRRAT 73
           GGGAGP GA  GG GGG   G P  G+ G+K                 S     +     
Sbjct: 47  GGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEEL 106

Query: 74  AKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
              R     RER R ++ N AFA LRK++PTLP D KLSKI+ L+LA  YI +L  VL
Sbjct: 107 QTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVL 163


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 66.6 bits (161), Expect = 5e-12
 Identities = 47/102 (46%), Positives = 53/102 (51%), Gaps = 26/102 (25%)

Query: 30  AGPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVE 89
           AG   AG GGPGG          PGR         E R+R  A A        RER R  
Sbjct: 56  AGGRRAGGGGPGG---------RPGR---------EPRQRHTANA--------RERDRTN 89

Query: 90  AFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
           + N AF  LR L+PT P D+KLSKIE LRLA  YIS+L +VL
Sbjct: 90  SVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVL 131


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 66.6 bits (161), Expect = 5e-12
 Identities = 47/102 (46%), Positives = 53/102 (51%), Gaps = 26/102 (25%)

Query: 30  AGPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVE 89
           AG   AG GGPGG          PGR         E R+R  A A        RER R  
Sbjct: 56  AGGRRAGGGGPGG---------RPGR---------EPRQRHTANA--------RERDRTN 89

Query: 90  AFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
           + N AF  LR L+PT P D+KLSKIE LRLA  YIS+L +VL
Sbjct: 90  SVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVL 131


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 66.2 bits (160), Expect = 7e-12
 Identities = 46/125 (36%), Positives = 60/125 (48%), Gaps = 28/125 (22%)

Query: 7   TMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREER 66
           +M L   P ++   +G      G  P GAGP G GG     P P                
Sbjct: 59  SMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGG-----PRPV--------------- 98

Query: 67  RRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISY 126
             +RR TA        +ER R ++ N AFAELR+ +P +P D KLSKI+ LRLA  YI+Y
Sbjct: 99  --KRRGTAN------RKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAY 150

Query: 127 LNHVL 131
           L  +L
Sbjct: 151 LMDLL 155


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 65.5 bits (158), Expect = 1e-11
 Identities = 46/116 (39%), Positives = 60/116 (51%), Gaps = 17/116 (14%)

Query: 17  SETESGFSDCGGGAGPDGAGPG-GPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAK 75
           SE+++     G   GP+ A  G GPGGG+  G   G  G   +                +
Sbjct: 29  SESDASDQSFGCCEGPEAARRGPGPGGGRRAG---GGGGAGPV-------------VVVR 72

Query: 76  YRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
            R A   RER R ++ N AF  LR L+PT P D+KLSKIE LRLA  YI++L +VL
Sbjct: 73  QRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVL 128


>gi|239749439 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 64.7 bits (156), Expect = 2e-11
 Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 25/101 (24%)

Query: 31  GPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEA 90
           G  G GP GPGGG   G   G P                         A+A RER RV+ 
Sbjct: 30  GRTGPGPAGPGGGSRSGS--GRPA-----------------------AANAARERSRVQT 64

Query: 91  FNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
              AF EL++ LP++PPD KLSK+++L LA  YI++L   L
Sbjct: 65  LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSL 105


>gi|239743573 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 64.7 bits (156), Expect = 2e-11
 Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 25/101 (24%)

Query: 31  GPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEA 90
           G  G GP GPGGG   G   G P                         A+A RER RV+ 
Sbjct: 30  GRTGPGPAGPGGGSRSGS--GRPA-----------------------AANAARERSRVQT 64

Query: 91  FNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
              AF EL++ LP++PPD KLSK+++L LA  YI++L   L
Sbjct: 65  LRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSL 105


>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
           sapiens]
          Length = 215

 Score = 63.2 bits (152), Expect = 6e-11
 Identities = 47/109 (43%), Positives = 57/109 (52%), Gaps = 17/109 (15%)

Query: 30  AGPD----GAGPGGPGGGQARGPE--PGE-PGRKDLQHLSREERRRRRRATAKYRTAHAT 82
           A PD    G  P       A GP+  PG+ PGR  L+ L     RR+     K       
Sbjct: 52  AAPDFPAGGPPPAAAAAATAYGPDARPGQSPGR--LEALGGRLGRRKGSGPKK------- 102

Query: 83  RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
            ER R E+ N AFAELR+ +P +P D KLSKI+ LRLA  YI+YL  VL
Sbjct: 103 -ERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVL 150


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 62.8 bits (151), Expect = 8e-11
 Identities = 52/131 (39%), Positives = 70/131 (53%), Gaps = 22/131 (16%)

Query: 22  GFSDCGGGAG---PDGAGPGG----PGGGQA------RGPEPGEPGRKDLQHLS-----R 63
           G  D GGG G     GA PGG    PG   +       G     PG + L+ LS      
Sbjct: 90  GEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGAR-LRGLSGAAAAA 148

Query: 64  EERRRRRRATAKY---RTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA 120
             RRRR R+ A+    R A   RER R+++ N AF  LR  +PTLP +K+LSK++ LRLA
Sbjct: 149 ARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLA 208

Query: 121 ICYISYLNHVL 131
           I YI++L+ ++
Sbjct: 209 IGYINFLSELV 219



 Score = 28.5 bits (62), Expect = 1.6
 Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 3/30 (10%)

Query: 27  GGGAGPDGAGPGGPGGGQARGPEPGEPGRK 56
           GGGAG  G GPGG  GG+  G  PG   +K
Sbjct: 227 GGGAGGCG-GPGG--GGRLGGDSPGSQAQK 253


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 62.8 bits (151), Expect = 8e-11
 Identities = 33/51 (64%), Positives = 41/51 (80%)

Query: 82  TRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 132
           +RER R +  N AFAELRKL+PT PPDKKLSK EILRLA+ YI++L  +L+
Sbjct: 194 SRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLN 244


>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
          Length = 108

 Score = 62.0 bits (149), Expect = 1e-10
 Identities = 33/50 (66%), Positives = 39/50 (78%)

Query: 82  TRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
           TRER R +  N AFA+LRKL+PT PPDKKLSK E LRLA+ YI++L  VL
Sbjct: 9   TRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVL 58


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 61.2 bits (147), Expect = 2e-10
 Identities = 32/50 (64%), Positives = 39/50 (78%)

Query: 82  TRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
           +RER R +  N AFAELRKLLPT PPD+KLSK E+LRLA+ YI +L  +L
Sbjct: 157 SRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLL 206


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 59.7 bits (143), Expect = 7e-10
 Identities = 43/133 (32%), Positives = 57/133 (42%), Gaps = 18/133 (13%)

Query: 4   NSDTMELDLPPTHSETESGFSDCGGGAG-----PDGAGPGGPGGGQARGPEPGEPGRKDL 58
           NS   E D  P   E        G   G     P  AG GG GG    G +   P +   
Sbjct: 44  NSSAEEED--PDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSA 101

Query: 59  QHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR 118
               + +R            A   RER R+   + AF+ L+  LP +PPD KLSK++ LR
Sbjct: 102 AECKQSQRN-----------AANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLR 150

Query: 119 LAICYISYLNHVL 131
           LA  YI++L  +L
Sbjct: 151 LASSYIAHLRQLL 163


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 59.3 bits (142), Expect = 9e-10
 Identities = 37/84 (44%), Positives = 48/84 (57%), Gaps = 7/84 (8%)

Query: 48  PEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPP 107
           P PG+ G+K        E  + +R  A        RER R ++ N AFA LRK++PTLP 
Sbjct: 45  PTPGKRGKKGSPSAQSFEELQSQRILAN------VRERQRTQSLNEAFAALRKIIPTLPS 98

Query: 108 DKKLSKIEILRLAICYISYLNHVL 131
           D KLSKI+ L+LA  YI +L  VL
Sbjct: 99  D-KLSKIQTLKLAARYIDFLYQVL 121


>gi|38202237 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 59.3 bits (142), Expect = 9e-10
 Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 17/133 (12%)

Query: 2   MLNSDTMELDLPP---THSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDL 58
           ML  D +++D      T +E+    S+C  G+   G G  G    + + P    P    L
Sbjct: 17  MLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGK---RRKAPTKKSP----L 69

Query: 59  QHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR 118
             +S+E ++ +R A          RER R+   + AF+ L+  LP +PPD KLSK++ LR
Sbjct: 70  SGVSQEGKQVQRNAAN-------ARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLR 122

Query: 119 LAICYISYLNHVL 131
           LA  YI++L  +L
Sbjct: 123 LASSYIAHLRQIL 135


>gi|38202239 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 59.3 bits (142), Expect = 9e-10
 Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 17/133 (12%)

Query: 2   MLNSDTMELDLPP---THSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDL 58
           ML  D +++D      T +E+    S+C  G+   G G  G    + + P    P    L
Sbjct: 17  MLECDGLKMDSNKEFVTSNESTEESSNCENGSPQKGRGGLGK---RRKAPTKKSP----L 69

Query: 59  QHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILR 118
             +S+E ++ +R A          RER R+   + AF+ L+  LP +PPD KLSK++ LR
Sbjct: 70  SGVSQEGKQVQRNAAN-------ARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLR 122

Query: 119 LAICYISYLNHVL 131
           LA  YI++L  +L
Sbjct: 123 LASSYIAHLRQIL 135


>gi|239754900 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 58.5 bits (140), Expect = 1e-09
 Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 25/101 (24%)

Query: 31  GPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEA 90
           G  G GP G GGG   G   G P  ++                       A RER RV+ 
Sbjct: 30  GRTGPGPAGLGGGSCSGS--GRPAAEN-----------------------AARERSRVQT 64

Query: 91  FNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
              AF E+++ LP++PPD KLSK+++L LA  YI++L   L
Sbjct: 65  LRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSL 105


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 30/66 (45%), Positives = 43/66 (65%)

Query: 67  RRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISY 126
           +R+R  T   R A   RER R+   N AF +LR+ +PT   +K+LS+IE LRLAI YIS+
Sbjct: 93  KRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISF 152

Query: 127 LNHVLD 132
           +  +L+
Sbjct: 153 MTELLE 158


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score = 54.7 bits (130), Expect = 2e-08
 Identities = 51/131 (38%), Positives = 57/131 (43%), Gaps = 21/131 (16%)

Query: 18  ETESGFSDCGGGAGPDGAGPG-GPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKY 76
           E E G S  GG     GA  G G  GG A G E   P R  L  L  + +RR  RA A  
Sbjct: 42  EEEPGAS--GGARRQRGAEAGQGARGGVAAGAEGCRPAR--LLGLVHDCKRRPSRARAVS 97

Query: 77  RTAHAT----------------RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA 120
           R A                   RER R+   N A   LR++LPT P D KL+KIE LR A
Sbjct: 98  RGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFA 157

Query: 121 ICYISYLNHVL 131
             YI  L   L
Sbjct: 158 HNYIWALTETL 168


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 53.5 bits (127), Expect = 5e-08
 Identities = 37/96 (38%), Positives = 46/96 (47%), Gaps = 13/96 (13%)

Query: 32  PDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAF 91
           P  A    PG G+ R P P  PG              RR ++ + R     RER R+   
Sbjct: 45  PARAAARAPGEGRRRRPGPSGPGG-------------RRDSSIQRRLESNERERQRMHKL 91

Query: 92  NLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYL 127
           N AF  LR+++P +  DKKLSKIE L LA  YI  L
Sbjct: 92  NNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSL 127


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 51.6 bits (122), Expect = 2e-07
 Identities = 27/63 (42%), Positives = 38/63 (60%)

Query: 69  RRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLN 128
           R  + A+ R A   RER R++  N AF  LR+++P    DKKLSK E L++A+ YI  L 
Sbjct: 34  RLESAARRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALT 93

Query: 129 HVL 131
            +L
Sbjct: 94  RIL 96


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 42/127 (33%), Positives = 56/127 (44%), Gaps = 15/127 (11%)

Query: 7   TMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREER 66
           T     PP+ + T    ++       +G   G P   +AR      P  K    LS++ R
Sbjct: 30  TCPTSAPPSPTRTRGNCAEA-----EEGGCRGAPRKLRARRGGRSRP--KSELALSKQRR 82

Query: 67  RRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISY 126
            RR++A          RER R+   N A   LR +LPT P D KL+KIE LR A  YI  
Sbjct: 83  SRRKKAN--------DRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWA 134

Query: 127 LNHVLDV 133
           L   L +
Sbjct: 135 LTQTLRI 141


>gi|75677394 transcription factor 23 [Homo sapiens]
          Length = 214

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 25/52 (48%), Positives = 33/52 (63%)

Query: 80  HATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131
           +A RER RV     AF  L+  LP +PPD KLSK+++L LA  YI++L   L
Sbjct: 81  NAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTL 132


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 50.4 bits (119), Expect = 4e-07
 Identities = 47/147 (31%), Positives = 61/147 (41%), Gaps = 29/147 (19%)

Query: 14  PTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPE------PGEPGRKDLQHLSR---- 63
           P   ET     DC   +G D +G        AR  +      P  P R+   ++SR    
Sbjct: 2   PARLETCISDLDCASSSGSDLSGFLTDEEDCARLQQAASASGPPAPARRGAPNISRASEV 61

Query: 64  ------EERRRRRRATAKYRTA---HATR----------ERIRVEAFNLAFAELRKLLPT 104
                 E+ RRRRR   + R+    H+ R          ER R+   N A   LR +LP+
Sbjct: 62  PGAQDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPS 121

Query: 105 LPPDKKLSKIEILRLAICYISYLNHVL 131
            P D KL+KIE LR A  YI  L   L
Sbjct: 122 FPDDTKLTKIETLRFAYNYIWALAETL 148


>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
          Length = 397

 Score = 49.7 bits (117), Expect = 7e-07
 Identities = 37/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%)

Query: 14  PTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRAT 73
           P  S   SG   C G  G                P+P     +  +  +   RR R    
Sbjct: 33  PASSSDSSGSCPCDGARG-------------LPQPQPPSCSSRAAEAAATTPRRARTGPA 79

Query: 74  AKYRTAHATRERIRVEAFNLAFAELRKLLPT--LPPDKKLSKIEILRLAICYISYLNHVL 131
              R + + RE++R+     A  ELR+ LP    P  + L+KIE LRLAI YI +L+ VL
Sbjct: 80  GGQRQSASEREKLRMRTLARALHELRRFLPPSLAPAGQSLTKIETLRLAIRYIGHLSAVL 139


>gi|55743094 achaete-scute complex homolog 1 [Homo sapiens]
          Length = 236

 Score = 49.3 bits (116), Expect = 9e-07
 Identities = 39/110 (35%), Positives = 53/110 (48%), Gaps = 15/110 (13%)

Query: 35  AGPGGP-GGGQARGPEPGEPGRKDLQHLSREERR-----------RRRRATAKYRTAHAT 82
           A  G P GGG    P+  +  R     L R +RR           +++ A    R     
Sbjct: 69  AADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNE--- 125

Query: 83  RERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 132
           RER RV+  NL FA LR+ +P    +KK+SK+E LR A+ YI  L  +LD
Sbjct: 126 RERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLD 175


>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
          Length = 337

 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 17/101 (16%)

Query: 50  PGEPGRKDLQHLSREE-------RRR--RRRATAKYRTAHA--------TRERIRVEAFN 92
           PGE   K+ +   REE       RRR  R++ T K R             RER R+   N
Sbjct: 52  PGEETEKEEEEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLN 111

Query: 93  LAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV 133
            A   LRK++P     +KLSKIE LRLA  YI  L+ +L +
Sbjct: 112 DALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRI 152


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.138    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,934,717
Number of Sequences: 37866
Number of extensions: 411429
Number of successful extensions: 9587
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 441
Number of HSP's successfully gapped in prelim test: 374
Number of HSP's that attempted gapping in prelim test: 4924
Number of HSP's gapped (non-prelim): 3813
length of query: 133
length of database: 18,247,518
effective HSP length: 91
effective length of query: 42
effective length of database: 14,801,712
effective search space: 621671904
effective search space used: 621671904
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.