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Search of human proteins with 5031785
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031785 interleukin 12 receptor, beta 1 isoform 1 precursor
[Homo sapiens]
(662 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031785 interleukin 12 receptor, beta 1 isoform 1 precursor [... 1382 0.0
gi|24497440 interleukin 12 receptor, beta 1 isoform 2 precursor ... 721 0.0
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 50 9e-06
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 47 7e-05
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 47 7e-05
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 47 7e-05
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 46 1e-04
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 46 1e-04
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 42 0.002
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 42 0.002
gi|224994173 roundabout 1 isoform d [Homo sapiens] 42 0.002
gi|224994171 roundabout 1 isoform c [Homo sapiens] 42 0.002
gi|19743806 roundabout 1 isoform b [Homo sapiens] 42 0.002
gi|110349719 titin isoform N2-A [Homo sapiens] 42 0.002
gi|110349717 titin isoform novex-2 [Homo sapiens] 42 0.002
gi|110349713 titin isoform novex-1 [Homo sapiens] 42 0.002
gi|110349715 titin isoform N2-B [Homo sapiens] 42 0.002
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 42 0.002
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 42 0.002
gi|4506569 roundabout 1 isoform a [Homo sapiens] 42 0.002
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 41 0.003
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 41 0.003
gi|4885491 myeloproliferative leukemia virus oncogene precursor ... 41 0.004
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 40 0.009
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 39 0.012
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 39 0.012
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 39 0.015
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 38 0.034
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 38 0.034
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 37 0.076
>gi|5031785 interleukin 12 receptor, beta 1 isoform 1 precursor
[Homo sapiens]
Length = 662
Score = 1382 bits (3578), Expect = 0.0
Identities = 662/662 (100%), Positives = 662/662 (100%)
Query: 1 MEPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRY 60
MEPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRY
Sbjct: 1 MEPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRY 60
Query: 61 ECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWAR 120
ECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWAR
Sbjct: 61 ECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWAR 120
Query: 121 NQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSP 180
NQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSP
Sbjct: 121 NQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSP 180
Query: 181 WKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSSWSKWSSPVCVPPENPPQPQ 240
WKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSSWSKWSSPVCVPPENPPQPQ
Sbjct: 181 WKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSSWSKWSSPVCVPPENPPQPQ 240
Query: 241 VRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRT 300
VRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRT
Sbjct: 241 VRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRT 300
Query: 301 LHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADTHTEPVALNISVGTNGTTMYWPA 360
LHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADTHTEPVALNISVGTNGTTMYWPA
Sbjct: 301 LHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADTHTEPVALNISVGTNGTTMYWPA 360
Query: 361 RAQSMTYCIEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKCYYITIFA 420
RAQSMTYCIEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKCYYITIFA
Sbjct: 361 RAQSMTYCIEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKCYYITIFA 420
Query: 421 SAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKE 480
SAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKE
Sbjct: 421 SAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKE 480
Query: 481 YVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIE 540
YVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIE
Sbjct: 481 YVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIE 540
Query: 541 VQVSDWLIFFASLGSFLSILLVGVLGYLGLNRAARHLCPPLPTPCASSAIEFPGGKETWQ 600
VQVSDWLIFFASLGSFLSILLVGVLGYLGLNRAARHLCPPLPTPCASSAIEFPGGKETWQ
Sbjct: 541 VQVSDWLIFFASLGSFLSILLVGVLGYLGLNRAARHLCPPLPTPCASSAIEFPGGKETWQ 600
Query: 601 WINPVDFQEEASLQEALVVEMSWDKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKA 660
WINPVDFQEEASLQEALVVEMSWDKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKA
Sbjct: 601 WINPVDFQEEASLQEALVVEMSWDKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKA 660
Query: 661 KM 662
KM
Sbjct: 661 KM 662
>gi|24497440 interleukin 12 receptor, beta 1 isoform 2 precursor
[Homo sapiens]
Length = 381
Score = 721 bits (1860), Expect = 0.0
Identities = 340/341 (99%), Positives = 341/341 (100%)
Query: 1 MEPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRY 60
MEPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRY
Sbjct: 1 MEPLVTWVVPLLFLFLLSRQGAACRTSECCFQDPPYPDADSGSASGPRDLRCYRISSDRY 60
Query: 61 ECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWAR 120
ECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWAR
Sbjct: 61 ECSWQYEGPTAGVSHFLRCCLSSGRCCYFAAGSATRLQFSDQAGVSVLYTVTLWVESWAR 120
Query: 121 NQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSP 180
NQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSP
Sbjct: 121 NQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAGQLRMEWETPDNQVGAEVQFRHRTPSSP 180
Query: 181 WKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSSWSKWSSPVCVPPENPPQPQ 240
WKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSSWSKWSSPVCVPPENPPQPQ
Sbjct: 181 WKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSSWSKWSSPVCVPPENPPQPQ 240
Query: 241 VRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRT 300
VRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRT
Sbjct: 241 VRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQLHMLSCPCKAKATRT 300
Query: 301 LHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADTHTE 341
LHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADTHT+
Sbjct: 301 LHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWHIPADTHTD 341
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 49.7 bits (117), Expect = 9e-06
Identities = 41/139 (29%), Positives = 62/139 (44%), Gaps = 15/139 (10%)
Query: 113 LWVESWARNQTEKSPEVTLQLYNSVKYEPPLGDIKVSKLAG---QLRMEWETP----DNQ 165
+WVE+ R + +S +TL + + V +PP D+ VS++ G QL + W +P D
Sbjct: 209 IWVEATNRLGSARSDVLTLDILDVVTTDPP-PDVHVSRVGGLEDQLSVRWVSPPALKDFL 267
Query: 166 VGAEVQFRHRTPSS-PWKLGDCGPQDDDTESCLCPLEMNVAQEFQLRRRQLGSQGSS--- 221
A+ Q R+R S WK+ D + T L L+ Q+R G GS
Sbjct: 268 FQAKYQIRYRVEDSVDWKVVD--DVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAG 325
Query: 222 -WSKWSSPVCVPPENPPQP 239
WS+WS P +P
Sbjct: 326 IWSEWSHPTAASTPRSERP 344
Score = 34.3 bits (77), Expect = 0.38
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 17/94 (18%)
Query: 451 HVSVKNHSLDSVSVDWAPSLLSTCPGVLKE------YVVRCRDEDSKQVSEHPVQPTETQ 504
HVS D +SV W P LK+ Y +R R EDS +T
Sbjct: 242 HVSRVGGLEDQLSVRWVS------PPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTS 295
Query: 505 VTLSGLRAGVAYTVQVRADTAWL-----RGVWSQ 533
L+GL+ G Y VQVR + + G+WS+
Sbjct: 296 CRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSE 329
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 46.6 bits (109), Expect = 7e-05
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 447 GTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVS-EHPVQPTETQV 505
G P ++ + + SV + W P +L+ G++ +Y + RD + + E + P +T +
Sbjct: 920 GFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTM 979
Query: 506 TLSGLRAGVAYTVQVRADTAWLRGVWSQPQRF 537
TL+GL+ Y V+VRA T+ G +S +F
Sbjct: 980 TLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQF 1011
Score = 32.3 bits (72), Expect = 1.4
Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
Query: 414 YYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLST 473
YY + A+ P+ L + +S SA P +S + S S+ V W P +
Sbjct: 581 YYFRL-AARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSWQPPPVEK 637
Query: 474 CPGVLKEYVVRCRDEDSKQVSEHPVQ--PTE-TQVTLSGLRAGVAYTVQVRADTAWLRGV 530
G++ EY ++ D + H + P++ T+ L L Y + V A T V
Sbjct: 638 QNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHT----DV 693
Query: 531 WSQPQRFSIEVQVSD 545
P+ S+ ++ ++
Sbjct: 694 GPGPESLSVLIRTNE 708
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 46.6 bits (109), Expect = 7e-05
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 447 GTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVS-EHPVQPTETQV 505
G P ++ + + SV + W P +L+ G++ +Y + RD + + E + P +T +
Sbjct: 907 GFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTM 966
Query: 506 TLSGLRAGVAYTVQVRADTAWLRGVWSQPQRF 537
TL+GL+ Y V+VRA T+ G +S +F
Sbjct: 967 TLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQF 998
Score = 32.3 bits (72), Expect = 1.4
Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
Query: 414 YYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLST 473
YY + A+ P+ L + +S SA P +S + S S+ V W P +
Sbjct: 568 YYFRL-AARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSWQPPPVEK 624
Query: 474 CPGVLKEYVVRCRDEDSKQVSEHPVQ--PTE-TQVTLSGLRAGVAYTVQVRADTAWLRGV 530
G++ EY ++ D + H + P++ T+ L L Y + V A T V
Sbjct: 625 QNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHT----DV 680
Query: 531 WSQPQRFSIEVQVSD 545
P+ S+ ++ ++
Sbjct: 681 GPGPESLSVLIRTNE 695
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 46.6 bits (109), Expect = 7e-05
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 447 GTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVS-EHPVQPTETQV 505
G P ++ + + SV + W P +L+ G++ +Y + RD + + E + P +T +
Sbjct: 911 GFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTM 970
Query: 506 TLSGLRAGVAYTVQVRADTAWLRGVWSQPQRF 537
TL+GL+ Y V+VRA T+ G +S +F
Sbjct: 971 TLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQF 1002
Score = 32.3 bits (72), Expect = 1.4
Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
Query: 414 YYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLST 473
YY + A+ P+ L + +S SA P +S + S S+ V W P +
Sbjct: 581 YYFRL-AARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSWQPPPVEK 637
Query: 474 CPGVLKEYVVRCRDEDSKQVSEHPVQ--PTE-TQVTLSGLRAGVAYTVQVRADTAWLRGV 530
G++ EY ++ D + H + P++ T+ L L Y + V A T V
Sbjct: 638 QNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHT----DV 693
Query: 531 WSQPQRFSIEVQVSD 545
P+ S+ ++ ++
Sbjct: 694 GPGPESLSVLIRTNE 708
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 46.2 bits (108), Expect = 1e-04
Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 18/142 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
++V +++ S+SV W P G+++EY + C +++ V V + GL
Sbjct: 762 LTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLF 821
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQRF---------------SIEVQVSDWL---IFFASL 553
G+ Y V+V A T+ GV S+PQ SI Q++D + F A +
Sbjct: 822 PGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGI 881
Query: 554 GSFLSILLVGVLGYLGLNRAAR 575
G ++L+G +L R R
Sbjct: 882 GGACWVILMGFSIWLYWRRKKR 903
Score = 32.0 bits (71), Expect = 1.9
Identities = 26/103 (25%), Positives = 38/103 (36%), Gaps = 10/103 (9%)
Query: 428 TLWSTVLSTYHFGGNASA-------AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKE 480
T WS VL G S G P V + + +SV++ W P T P
Sbjct: 513 TSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPA--SA 570
Query: 481 YVVRCRDEDSKQVSEHPVQPTETQV-TLSGLRAGVAYTVQVRA 522
Y++ + + +T + T+ GLR Y VRA
Sbjct: 571 YIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRA 613
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 46.2 bits (108), Expect = 1e-04
Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 18/142 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
++V +++ S+SV W P G+++EY + C +++ V V + GL
Sbjct: 746 LTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLF 805
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQRF---------------SIEVQVSDWL---IFFASL 553
G+ Y V+V A T+ GV S+PQ SI Q++D + F A +
Sbjct: 806 PGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGI 865
Query: 554 GSFLSILLVGVLGYLGLNRAAR 575
G ++L+G +L R R
Sbjct: 866 GGACWVILMGFSIWLYWRRKKR 887
Score = 32.0 bits (71), Expect = 1.9
Identities = 26/103 (25%), Positives = 38/103 (36%), Gaps = 10/103 (9%)
Query: 428 TLWSTVLSTYHFGGNASA-------AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKE 480
T WS VL G S G P V + + +SV++ W P T P
Sbjct: 497 TSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPA--SA 554
Query: 481 YVVRCRDEDSKQVSEHPVQPTETQV-TLSGLRAGVAYTVQVRA 522
Y++ + + +T + T+ GLR Y VRA
Sbjct: 555 YIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRA 597
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 42.0 bits (97), Expect = 0.002
Identities = 80/351 (22%), Positives = 120/351 (34%), Gaps = 38/351 (10%)
Query: 204 VAQEFQLRRRQLG--SQGSSWSKWSSPVCVPPENPPQPQVRFSVEQLGQDG--------- 252
+ ++ R +G S S + W S V + PP V V + G+
Sbjct: 365 IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESV---VTRTGEQAPASAPRNVQ 421
Query: 253 RRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQL-HMLSCPCKAKATRTLHLGKMPYLSG 311
R L+ Q E P GL G V Y ++ H + K +L L
Sbjct: 422 ARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLED 481
Query: 312 AAYNVAVISSNQFGPGLNQTWHIPADTHTEPVALNISVGTNGTTMYWPARAQSMT-YCIE 370
Y V V++ G G ++P+ + G G M A A+S T +
Sbjct: 482 ETYTVRVLAFTSVGDG----------PLSDPIQVKTQQGVPGQPMNLRAEARSETSITLS 531
Query: 371 WQPVGQDGGLATCSLTAPQDPDPAGMATY----SWSRESGAMGQEKCYYITIFASAHPEK 426
W P Q+ + L D T+ S+ E E + + A+ P+
Sbjct: 532 WSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRL---AARSPQG 588
Query: 427 LTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCR 486
L ++ V+ SA P V + ++ V W P T G L Y VR R
Sbjct: 589 LGAFTPVVRQRTLQSKPSAP--PQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYR 646
Query: 487 ---DEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQP 534
ED + + + PT TQ+ L L Y + A T G S P
Sbjct: 647 PLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSP 697
Score = 38.1 bits (87), Expect = 0.026
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 456 NHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPT------ETQVTLSG 509
N S +V + W P + + G + +Y V R+ + + P E +TL G
Sbjct: 918 NASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQG 977
Query: 510 LRAGVAYTVQVRADTAWLRGVWSQPQRF 537
L+ AY +QVRA T G +S P R+
Sbjct: 978 LKPDTAYDLQVRAHTRRGPGPFSPPVRY 1005
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 42.0 bits (97), Expect = 0.002
Identities = 80/351 (22%), Positives = 120/351 (34%), Gaps = 38/351 (10%)
Query: 204 VAQEFQLRRRQLG--SQGSSWSKWSSPVCVPPENPPQPQVRFSVEQLGQDG--------- 252
+ ++ R +G S S + W S V + PP V V + G+
Sbjct: 378 IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESV---VTRTGEQAPASAPRNVQ 434
Query: 253 RRRLTLKEQPTQLELPEGCQGLAPGTEVTYRLQL-HMLSCPCKAKATRTLHLGKMPYLSG 311
R L+ Q E P GL G V Y ++ H + K +L L
Sbjct: 435 ARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLED 494
Query: 312 AAYNVAVISSNQFGPGLNQTWHIPADTHTEPVALNISVGTNGTTMYWPARAQSMT-YCIE 370
Y V V++ G G ++P+ + G G M A A+S T +
Sbjct: 495 ETYTVRVLAFTSVGDG----------PLSDPIQVKTQQGVPGQPMNLRAEARSETSITLS 544
Query: 371 WQPVGQDGGLATCSLTAPQDPDPAGMATY----SWSRESGAMGQEKCYYITIFASAHPEK 426
W P Q+ + L D T+ S+ E E + + A+ P+
Sbjct: 545 WSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRL---AARSPQG 601
Query: 427 LTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCR 486
L ++ V+ SA P V + ++ V W P T G L Y VR R
Sbjct: 602 LGAFTPVVRQRTLQSKPSAP--PQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYR 659
Query: 487 ---DEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQP 534
ED + + + PT TQ+ L L Y + A T G S P
Sbjct: 660 PLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSP 710
Score = 38.1 bits (87), Expect = 0.026
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 456 NHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPT------ETQVTLSG 509
N S +V + W P + + G + +Y V R+ + + P E +TL G
Sbjct: 940 NASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQG 999
Query: 510 LRAGVAYTVQVRADTAWLRGVWSQPQRF 537
L+ AY +QVRA T G +S P R+
Sbjct: 1000 LKPDTAYDLQVRAHTRRGPGPFSPPVRY 1027
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
VS + + ++ V W P T G+++EY V C +++ V + V + L
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 807
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQ---------------RFSIEVQVSDWL---IFFASL 553
G+ Y+V+V A T GV S+PQ + S+ Q+SD + F A +
Sbjct: 808 PGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFIAGI 867
Query: 554 GSFLSILLVGVLGYLGLNRAARH 576
G+ I+L+ +L +R R+
Sbjct: 868 GAACWIILMVFSIWLYRHRKKRN 890
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
VS + + ++ V W P T G+++EY V C +++ V + V + L
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 807
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQ---------------RFSIEVQVSDWL---IFFASL 553
G+ Y+V+V A T GV S+PQ + S+ Q+SD + F A +
Sbjct: 808 PGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFIAGI 867
Query: 554 GSFLSILLVGVLGYLGLNRAARH 576
G+ I+L+ +L +R R+
Sbjct: 868 GAACWIILMVFSIWLYRHRKKRN 890
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
VS + + ++ V W P T G+++EY V C +++ V + V + L
Sbjct: 745 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 804
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQ---------------RFSIEVQVSDWL---IFFASL 553
G+ Y+V+V A T GV S+PQ + S+ Q+SD + F A +
Sbjct: 805 PGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFIAGI 864
Query: 554 GSFLSILLVGVLGYLGLNRAARH 576
G+ I+L+ +L +R R+
Sbjct: 865 GAACWIILMVFSIWLYRHRKKRN 887
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 10/113 (8%)
Query: 414 YYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLST 473
Y +T+ S ++ T+ VL T G P +V+VK S DS V W P ++
Sbjct: 19764 YILTLENSCGKKEYTIVVKVLDT---------PGPPVNVTVKEISKDSAYVTWEPPIIDG 19814
Query: 474 CPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAW 526
++ YVV+ RD + K S + ++T ++ L G +Y +V A+ +
Sbjct: 19815 GSPII-NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 19866
Score = 35.0 bits (79), Expect = 0.22
Identities = 39/166 (23%), Positives = 64/166 (38%), Gaps = 18/166 (10%)
Query: 378 GGLATCSLTAPQDPDPAGMATYSWSRESGAMGQ----EKCYYITIFASAHPEKLTLWSTV 433
GG A + P P +WSRE G EK T + + ++ +
Sbjct: 24039 GGSARIHIPFKGRPTPE----ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYI 24094
Query: 434 LSTYHFGGNASA---------AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVR 484
L + G+ SA G P +++VK DS + W P ++ V K YV+
Sbjct: 24095 LKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKV-KNYVID 24153
Query: 485 CRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGV 530
R+ K + + ++T + L G Y +V A+ + GV
Sbjct: 24154 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 24199
Score = 33.5 bits (75), Expect = 0.64
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 447 GTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVT 506
G P + VK + SV++ W P LL +K Y+V R+ K S +T
Sbjct: 21953 GPPQDLKVKEVTKTSVTLTWDPPLLDG-GSKIKNYIVEKRESTRKAYSTVATNCHKTSWK 22011
Query: 507 LSGLRAGVAYTVQVRADTAW 526
+ L+ G +Y +V A+ +
Sbjct: 22012 VDQLQEGCSYYFRVLAENEY 22031
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P ++ V + DSVS+ W P LL +K Y+V R+ K + + +
Sbjct: 23037 PVNLKVTEITKDSVSITWEPPLLDG-GSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 23095
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQ 533
L+ G +Y +V A+ + G+ +Q
Sbjct: 23096 QLQEGCSYYFRVTAENEYGIGLPAQ 23120
Score = 32.0 bits (71), Expect = 1.9
Identities = 36/178 (20%), Positives = 61/178 (34%), Gaps = 20/178 (11%)
Query: 369 IEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKC----------YYITI 418
I W+P DGG + + G W S A+ C YY +
Sbjct: 30742 ISWKPPADDGGSWITNYVVEKCEAKEGA---EWQLVSSAISVTTCRIVNLTENAGYYFRV 30798
Query: 419 FAS---AHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCP 475
A + L + S V+ F G P ++ + DS V W P
Sbjct: 30799 SAQNTFGISDPLEVSSVVIIKSPF----EKPGAPGKPTITAVTKDSCVVAWKPPASDGGA 30854
Query: 476 GVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQ 533
+ Y+ + + +K +S + ET ++ L G+ Y +V+ + WS+
Sbjct: 30855 KIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 30912
Score = 31.6 bits (70), Expect = 2.4
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P +++++ DSV++ W P L+ + Y+V R+ K + T+T +
Sbjct: 25202 PVNLTIREVKKDSVTLSWEPPLIDG-GAKITNYIVEKRETTRKAYATITNNCTKTTFRIE 25260
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQPQRFSIEVQVSD 545
L+ G +Y +V A + G+ P + V+VS+
Sbjct: 25261 NLQEGCSYYFRVLASNEYGIGL---PAETTEPVKVSE 25294
Score = 29.6 bits (65), Expect = 9.3
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 445 AAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRD-EDSKQVSEHPVQPTET 503
A P +V + + S +SVS+ W + Y+V RD D + TET
Sbjct: 26767 ACEPPRNVRITDISKNSVSLSWQQPAFDG-GSKITGYIVERRDLPDGRWTKASFTNVTET 26825
Query: 504 QVTLSGLRAGVAYTVQVRADTA 525
Q +SGL Y +V A A
Sbjct: 26826 QFIISGLTQNSQYEFRVFARNA 26847
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 10/113 (8%)
Query: 414 YYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLST 473
Y +T+ S ++ T+ VL T G P +V+VK S DS V W P ++
Sbjct: 13459 YILTLENSCGKKEYTIVVKVLDT---------PGPPVNVTVKEISKDSAYVTWEPPIIDG 13509
Query: 474 CPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAW 526
++ YVV+ RD + K S + ++T ++ L G +Y +V A+ +
Sbjct: 13510 GSPII-NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 13561
Score = 35.0 bits (79), Expect = 0.22
Identities = 39/166 (23%), Positives = 64/166 (38%), Gaps = 18/166 (10%)
Query: 378 GGLATCSLTAPQDPDPAGMATYSWSRESGAMGQ----EKCYYITIFASAHPEKLTLWSTV 433
GG A + P P +WSRE G EK T + + ++ +
Sbjct: 17734 GGSARIHIPFKGRPTPE----ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYI 17789
Query: 434 LSTYHFGGNASA---------AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVR 484
L + G+ SA G P +++VK DS + W P ++ V K YV+
Sbjct: 17790 LKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKV-KNYVID 17848
Query: 485 CRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGV 530
R+ K + + ++T + L G Y +V A+ + GV
Sbjct: 17849 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17894
Score = 33.5 bits (75), Expect = 0.64
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 447 GTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVT 506
G P + VK + SV++ W P LL +K Y+V R+ K S +T
Sbjct: 15648 GPPQDLKVKEVTKTSVTLTWDPPLLDG-GSKIKNYIVEKRESTRKAYSTVATNCHKTSWK 15706
Query: 507 LSGLRAGVAYTVQVRADTAW 526
+ L+ G +Y +V A+ +
Sbjct: 15707 VDQLQEGCSYYFRVLAENEY 15726
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P ++ V + DSVS+ W P LL +K Y+V R+ K + + +
Sbjct: 16732 PVNLKVTEITKDSVSITWEPPLLDG-GSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 16790
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQ 533
L+ G +Y +V A+ + G+ +Q
Sbjct: 16791 QLQEGCSYYFRVTAENEYGIGLPAQ 16815
Score = 32.0 bits (71), Expect = 1.9
Identities = 36/178 (20%), Positives = 61/178 (34%), Gaps = 20/178 (11%)
Query: 369 IEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKC----------YYITI 418
I W+P DGG + + G W S A+ C YY +
Sbjct: 24437 ISWKPPADDGGSWITNYVVEKCEAKEGA---EWQLVSSAISVTTCRIVNLTENAGYYFRV 24493
Query: 419 FAS---AHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCP 475
A + L + S V+ F G P ++ + DS V W P
Sbjct: 24494 SAQNTFGISDPLEVSSVVIIKSPF----EKPGAPGKPTITAVTKDSCVVAWKPPASDGGA 24549
Query: 476 GVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQ 533
+ Y+ + + +K +S + ET ++ L G+ Y +V+ + WS+
Sbjct: 24550 KIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 24607
Score = 31.6 bits (70), Expect = 2.4
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P +++++ DSV++ W P L+ + Y+V R+ K + T+T +
Sbjct: 18897 PVNLTIREVKKDSVTLSWEPPLIDG-GAKITNYIVEKRETTRKAYATITNNCTKTTFRIE 18955
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQPQRFSIEVQVSD 545
L+ G +Y +V A + G+ P + V+VS+
Sbjct: 18956 NLQEGCSYYFRVLASNEYGIGL---PAETTEPVKVSE 18989
Score = 29.6 bits (65), Expect = 9.3
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 445 AAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRD-EDSKQVSEHPVQPTET 503
A P +V + + S +SVS+ W + Y+V RD D + TET
Sbjct: 20462 ACEPPRNVRITDISKNSVSLSWQQPAFDG-GSKITGYIVERRDLPDGRWTKASFTNVTET 20520
Query: 504 QVTLSGLRAGVAYTVQVRADTA 525
Q +SGL Y +V A A
Sbjct: 20521 QFIISGLTQNSQYEFRVFARNA 20542
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 10/113 (8%)
Query: 414 YYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLST 473
Y +T+ S ++ T+ VL T G P +V+VK S DS V W P ++
Sbjct: 13392 YILTLENSCGKKEYTIVVKVLDT---------PGPPVNVTVKEISKDSAYVTWEPPIIDG 13442
Query: 474 CPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAW 526
++ YVV+ RD + K S + ++T ++ L G +Y +V A+ +
Sbjct: 13443 GSPII-NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 13494
Score = 35.0 bits (79), Expect = 0.22
Identities = 39/166 (23%), Positives = 64/166 (38%), Gaps = 18/166 (10%)
Query: 378 GGLATCSLTAPQDPDPAGMATYSWSRESGAMGQ----EKCYYITIFASAHPEKLTLWSTV 433
GG A + P P +WSRE G EK T + + ++ +
Sbjct: 17667 GGSARIHIPFKGRPTPE----ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYI 17722
Query: 434 LSTYHFGGNASA---------AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVR 484
L + G+ SA G P +++VK DS + W P ++ V K YV+
Sbjct: 17723 LKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKV-KNYVID 17781
Query: 485 CRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGV 530
R+ K + + ++T + L G Y +V A+ + GV
Sbjct: 17782 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17827
Score = 33.5 bits (75), Expect = 0.64
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 447 GTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVT 506
G P + VK + SV++ W P LL +K Y+V R+ K S +T
Sbjct: 15581 GPPQDLKVKEVTKTSVTLTWDPPLLDG-GSKIKNYIVEKRESTRKAYSTVATNCHKTSWK 15639
Query: 507 LSGLRAGVAYTVQVRADTAW 526
+ L+ G +Y +V A+ +
Sbjct: 15640 VDQLQEGCSYYFRVLAENEY 15659
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P ++ V + DSVS+ W P LL +K Y+V R+ K + + +
Sbjct: 16665 PVNLKVTEITKDSVSITWEPPLLDG-GSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 16723
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQ 533
L+ G +Y +V A+ + G+ +Q
Sbjct: 16724 QLQEGCSYYFRVTAENEYGIGLPAQ 16748
Score = 32.0 bits (71), Expect = 1.9
Identities = 36/178 (20%), Positives = 61/178 (34%), Gaps = 20/178 (11%)
Query: 369 IEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKC----------YYITI 418
I W+P DGG + + G W S A+ C YY +
Sbjct: 24370 ISWKPPADDGGSWITNYVVEKCEAKEGA---EWQLVSSAISVTTCRIVNLTENAGYYFRV 24426
Query: 419 FAS---AHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCP 475
A + L + S V+ F G P ++ + DS V W P
Sbjct: 24427 SAQNTFGISDPLEVSSVVIIKSPF----EKPGAPGKPTITAVTKDSCVVAWKPPASDGGA 24482
Query: 476 GVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQ 533
+ Y+ + + +K +S + ET ++ L G+ Y +V+ + WS+
Sbjct: 24483 KIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 24540
Score = 31.6 bits (70), Expect = 2.4
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P +++++ DSV++ W P L+ + Y+V R+ K + T+T +
Sbjct: 18830 PVNLTIREVKKDSVTLSWEPPLIDG-GAKITNYIVEKRETTRKAYATITNNCTKTTFRIE 18888
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQPQRFSIEVQVSD 545
L+ G +Y +V A + G+ P + V+VS+
Sbjct: 18889 NLQEGCSYYFRVLASNEYGIGL---PAETTEPVKVSE 18922
Score = 29.6 bits (65), Expect = 9.3
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 445 AAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRD-EDSKQVSEHPVQPTET 503
A P +V + + S +SVS+ W + Y+V RD D + TET
Sbjct: 20395 ACEPPRNVRITDISKNSVSLSWQQPAFDG-GSKITGYIVERRDLPDGRWTKASFTNVTET 20453
Query: 504 QVTLSGLRAGVAYTVQVRADTA 525
Q +SGL Y +V A A
Sbjct: 20454 QFIISGLTQNSQYEFRVFARNA 20475
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 10/113 (8%)
Query: 414 YYITIFASAHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLST 473
Y +T+ S ++ T+ VL T G P +V+VK S DS V W P ++
Sbjct: 13267 YILTLENSCGKKEYTIVVKVLDT---------PGPPVNVTVKEISKDSAYVTWEPPIIDG 13317
Query: 474 CPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAW 526
++ YVV+ RD + K S + ++T ++ L G +Y +V A+ +
Sbjct: 13318 GSPII-NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 13369
Score = 35.0 bits (79), Expect = 0.22
Identities = 39/166 (23%), Positives = 64/166 (38%), Gaps = 18/166 (10%)
Query: 378 GGLATCSLTAPQDPDPAGMATYSWSRESGAMGQ----EKCYYITIFASAHPEKLTLWSTV 433
GG A + P P +WSRE G EK T + + ++ +
Sbjct: 17542 GGSARIHIPFKGRPTPE----ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYI 17597
Query: 434 LSTYHFGGNASA---------AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVR 484
L + G+ SA G P +++VK DS + W P ++ V K YV+
Sbjct: 17598 LKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKV-KNYVID 17656
Query: 485 CRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGV 530
R+ K + + ++T + L G Y +V A+ + GV
Sbjct: 17657 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17702
Score = 33.5 bits (75), Expect = 0.64
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 447 GTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVT 506
G P + VK + SV++ W P LL +K Y+V R+ K S +T
Sbjct: 15456 GPPQDLKVKEVTKTSVTLTWDPPLLDG-GSKIKNYIVEKRESTRKAYSTVATNCHKTSWK 15514
Query: 507 LSGLRAGVAYTVQVRADTAW 526
+ L+ G +Y +V A+ +
Sbjct: 15515 VDQLQEGCSYYFRVLAENEY 15534
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P ++ V + DSVS+ W P LL +K Y+V R+ K + + +
Sbjct: 16540 PVNLKVTEITKDSVSITWEPPLLDG-GSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 16598
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQ 533
L+ G +Y +V A+ + G+ +Q
Sbjct: 16599 QLQEGCSYYFRVTAENEYGIGLPAQ 16623
Score = 32.0 bits (71), Expect = 1.9
Identities = 36/178 (20%), Positives = 61/178 (34%), Gaps = 20/178 (11%)
Query: 369 IEWQPVGQDGGLATCSLTAPQDPDPAGMATYSWSRESGAMGQEKC----------YYITI 418
I W+P DGG + + G W S A+ C YY +
Sbjct: 24245 ISWKPPADDGGSWITNYVVEKCEAKEGA---EWQLVSSAISVTTCRIVNLTENAGYYFRV 24301
Query: 419 FAS---AHPEKLTLWSTVLSTYHFGGNASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCP 475
A + L + S V+ F G P ++ + DS V W P
Sbjct: 24302 SAQNTFGISDPLEVSSVVIIKSPF----EKPGAPGKPTITAVTKDSCVVAWKPPASDGGA 24357
Query: 476 GVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQ 533
+ Y+ + + +K +S + ET ++ L G+ Y +V+ + WS+
Sbjct: 24358 KIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSE 24415
Score = 31.6 bits (70), Expect = 2.4
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 449 PHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLS 508
P +++++ DSV++ W P L+ + Y+V R+ K + T+T +
Sbjct: 18705 PVNLTIREVKKDSVTLSWEPPLIDG-GAKITNYIVEKRETTRKAYATITNNCTKTTFRIE 18763
Query: 509 GLRAGVAYTVQVRADTAWLRGVWSQPQRFSIEVQVSD 545
L+ G +Y +V A + G+ P + V+VS+
Sbjct: 18764 NLQEGCSYYFRVLASNEYGIGL---PAETTEPVKVSE 18797
Score = 29.6 bits (65), Expect = 9.3
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 445 AAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRD-EDSKQVSEHPVQPTET 503
A P +V + + S +SVS+ W + Y+V RD D + TET
Sbjct: 20270 ACEPPRNVRITDISKNSVSLSWQQPAFDG-GSKITGYIVERRDLPDGRWTKASFTNVTET 20328
Query: 504 QVTLSGLRAGVAYTVQVRADTA 525
Q +SGL Y +V A A
Sbjct: 20329 QFIISGLTQNSQYEFRVFARNA 20350
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
VS + + ++ V W P T G+++EY V C +++ V + V + L
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 807
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQ---------------RFSIEVQVSDWL---IFFASL 553
G+ Y+V+V A T GV S+PQ + S+ Q+SD + F A +
Sbjct: 808 PGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFIAGI 867
Query: 554 GSFLSILLVGVLGYLGLNRAARH 576
G+ I+L+ +L +R R+
Sbjct: 868 GAACWIILMVFSIWLYRHRKKRN 890
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
VS + + ++ V W P T G+++EY V C +++ V + V + L
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 807
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQ---------------RFSIEVQVSDWL---IFFASL 553
G+ Y+V+V A T GV S+PQ + S+ Q+SD + F A +
Sbjct: 808 PGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFIAGI 867
Query: 554 GSFLSILLVGVLGYLGLNRAARH 576
G+ I+L+ +L +R R+
Sbjct: 868 GAACWIILMVFSIWLYRHRKKRN 890
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 18/143 (12%)
Query: 452 VSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLR 511
VS + + ++ V W P T G+++EY V C +++ V + V + L
Sbjct: 784 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 843
Query: 512 AGVAYTVQVRADTAWLRGVWSQPQ---------------RFSIEVQVSDWL---IFFASL 553
G+ Y+V+V A T GV S+PQ + S+ Q+SD + F A +
Sbjct: 844 PGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFIAGI 903
Query: 554 GSFLSILLVGVLGYLGLNRAARH 576
G+ I+L+ +L +R R+
Sbjct: 904 GAACWIILMVFSIWLYRHRKKRN 926
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 446 AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQV 505
+G P ++ V + + + W P +L+ G + Y V RD +S+Q ++ T+T+
Sbjct: 916 SGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT--TDTRF 973
Query: 506 TLSGLRAGVAYTVQVRADTA 525
TL+GL+ Y ++VRA T+
Sbjct: 974 TLTGLKPDTTYDIKVRAWTS 993
Score = 30.8 bits (68), Expect = 4.2
Identities = 50/226 (22%), Positives = 81/226 (35%), Gaps = 22/226 (9%)
Query: 443 ASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTE 502
++ + P V + +V V W P + GV+ +Y V D + H V
Sbjct: 604 STPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGIS 663
Query: 503 TQVT---LSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIEVQVSDWLIFFASLGSFLSI 559
+ + L GL Y V VRA T G S P + V G +
Sbjct: 664 REHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPS--------GPPRKV 715
Query: 560 LLVGVLGYLGLNRAARHLCPPLPTPCASSAIEFPGGKETWQWINPVDFQEEASLQEALVV 619
+ LN A H+ LP P + G + T+ + + + +Q+ ++
Sbjct: 716 EVE------PLNSTAVHVYWKLPVPSKQHG-QIRGYQVTYVRLENGEPRGLPIIQDVMLA 768
Query: 620 EMSWDKGERTEPLEKT---ELPEGAPELALDTELSLEDGDRCKAKM 662
E W + E +E E T PE + + + DG R K K+
Sbjct: 769 EAQW-RPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 813
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 446 AGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQV 505
+G P ++ V + + + W P +L+ G + Y V RD +S+Q ++ T+T+
Sbjct: 907 SGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT--TDTRF 964
Query: 506 TLSGLRAGVAYTVQVRADTA 525
TL+GL+ Y ++VRA T+
Sbjct: 965 TLTGLKPDTTYDIKVRAWTS 984
Score = 29.6 bits (65), Expect = 9.3
Identities = 25/95 (26%), Positives = 36/95 (37%), Gaps = 3/95 (3%)
Query: 443 ASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTE 502
++ + P V + +V V W P + GV+ +Y V D + H V
Sbjct: 604 STPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGIS 663
Query: 503 TQVT---LSGLRAGVAYTVQVRADTAWLRGVWSQP 534
+ + L GL Y V VRA T G S P
Sbjct: 664 REHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSP 698
>gi|4885491 myeloproliferative leukemia virus oncogene precursor
[Homo sapiens]
Length = 635
Score = 40.8 bits (94), Expect = 0.004
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 24/172 (13%)
Query: 44 ASGPRDLRCYRISSDRYECSW-QYEGPTAGVSHFL---------RCCLSSGRCCYFAAGS 93
AS L+C+ + + C W + E +G L C LSS +F G+
Sbjct: 32 ASDSEPLKCFSRTFEDLTCFWDEEEAAPSGTYQLLYAYPREKPRACPLSSQSMPHF--GT 89
Query: 94 ATRLQFSDQAGVSVLYTVTLWVESWARNQTEKSPEVTLQLYNSVKYEPPLGDIKV--SKL 151
QF DQ V + + + LWV++ NQT + +SV P IK
Sbjct: 90 RYVCQFPDQEEVRLFFPLHLWVKNVFLNQTRTQ---RVLFVDSVGLPAPPSIIKAMGGSQ 146
Query: 152 AGQLRMEWETPDNQVG----AEVQFRHRTPSSPWKLGDCGPQDDDTESCLCP 199
G+L++ WE P ++ E+++ R P + G Q TE+C CP
Sbjct: 147 PGELQISWEEPAPEISDFLRYELRYGPRDPKN--STGPTVIQLIATETC-CP 195
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
Length = 1005
Score = 39.7 bits (91), Expect = 0.009
Identities = 20/58 (34%), Positives = 34/58 (58%)
Query: 476 GVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQ 533
G++ EY ++ ++D + S ++ T+ T+SGL+ G Y QVRA T+ G +SQ
Sbjct: 468 GIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQ 525
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 39.3 bits (90), Expect = 0.012
Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 444 SAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTET 503
SA H VS ++DS+++ W+ GV+ +Y ++ +++ + + ++
Sbjct: 437 SAVSIMHQVS---RTVDSITLSWSQP--DQPNGVILDYELQYYEKELSEYNATAIKSPTN 491
Query: 504 QVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRF 537
VT+ GL+AG Y QVRA T G +S F
Sbjct: 492 TVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYF 525
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 39.3 bits (90), Expect = 0.012
Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 444 SAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTET 503
SA H VS ++DS+++ W+ GV+ +Y ++ +++ + + ++
Sbjct: 437 SAVSIMHQVS---RTVDSITLSWSQP--DQPNGVILDYELQYYEKELSEYNATAIKSPTN 491
Query: 504 QVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRF 537
VT+ GL+AG Y QVRA T G +S F
Sbjct: 492 TVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYF 525
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 38.9 bits (89), Expect = 0.015
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 11/122 (9%)
Query: 458 SLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQVTLSGLRAGVAYT 517
S +S+S+ W G++ +Y V+ ++ ++ S ++ T VT+S L+ Y
Sbjct: 449 SRNSISLSWQEPEHPN--GIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYV 506
Query: 518 VQVRADTAWLRGVWSQ-------PQRFSIEVQVSDWLIFFASLGSFLSILLVGVLGYLGL 570
Q+RA TA G S+ P FSI + S + ++ + ++I+L+ V+ Y+ +
Sbjct: 507 FQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQ--VVMIAISAAVAIILLTVVIYVLI 564
Query: 571 NR 572
R
Sbjct: 565 GR 566
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
sapiens]
Length = 1015
Score = 37.7 bits (86), Expect = 0.034
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 442 NASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPT 501
N +A +V + +S+S+ W G++ EY ++ ++D ++ S ++
Sbjct: 465 NQAAPSPVTNVKKGKIAKNSISLSWQEP--DRPNGIILEYEIKYFEKD-QETSYTIIKSK 521
Query: 502 ETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIE 540
ET +T GL+ Y Q+RA TA GV+S +RF E
Sbjct: 522 ETTITAEGLKPASVYVFQIRARTAAGYGVFS--RRFEFE 558
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
Length = 1037
Score = 37.7 bits (86), Expect = 0.034
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 5/99 (5%)
Query: 442 NASAAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPT 501
N +A +V + +S+S+ W G++ EY ++ ++D ++ S ++
Sbjct: 465 NQAAPSPVTNVKKGKIAKNSISLSWQEP--DRPNGIILEYEIKYFEKD-QETSYTIIKSK 521
Query: 502 ETQVTLSGLRAGVAYTVQVRADTAWLRGVWSQPQRFSIE 540
ET +T GL+ Y Q+RA TA GV+S +RF E
Sbjct: 522 ETTITAEGLKPASVYVFQIRARTAAGYGVFS--RRFEFE 558
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 36.6 bits (83), Expect = 0.076
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 2/91 (2%)
Query: 446 AGTPHHVSVK--NHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTET 503
+G P V+V S++V W P L S GV+ EY + C +S+
Sbjct: 769 SGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQIWCLGNESRFHLNRSAAGWAR 828
Query: 504 QVTLSGLRAGVAYTVQVRADTAWLRGVWSQP 534
L GL G+ Y V A T+ GV S P
Sbjct: 829 SAMLRGLVPGLLYRTLVAAATSAGVGVPSAP 859
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,448,995
Number of Sequences: 37866
Number of extensions: 1538059
Number of successful extensions: 4265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 3962
Number of HSP's gapped (non-prelim): 354
length of query: 662
length of database: 18,247,518
effective HSP length: 109
effective length of query: 553
effective length of database: 14,120,124
effective search space: 7808428572
effective search space used: 7808428572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.