Guide to the Human Genome
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Name: MPL Sequence: fasta or formatted (635aa) NCBI GI: 4885491
Description:

myeloproliferative leukemia virus oncogene precursor

Referenced in:

Retroviral Oncogene Homologs
Platelets and Megakaryocytes
Hematopoiesis and Erythrocytes
RNA-binding Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         41           2
 C cysteine            3.5         22           2
 D aspartate           3.6         23           1
 E glutamate           6.0         38           4
 F phenylalanine       2.8         18           2
 G glycine             5.7         36           2
 H histidine           3.0         19           1
 I isoleucine          2.7         17           2
 K lysine              1.9         12           1
 L leucine            12.3         78           4
 M methionine          1.3          8           1
 N asparagine          1.9         12           1
 P proline             9.4         60           2
 Q glutamine           6.5         41           3
 R arginine            6.1         39           2
 S serine             10.1         64           2
 T threonine           6.1         39           2
 V valine              4.4         28           1
 W tryptophan          3.3         21           1
 Y tyrosine            3.0         19           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   myeloproliferative leukemia virus oncogene precursor ... 
EPOR                  0.027   erythropoietin receptor precursor 
CRLF1                 0.024   cytokine receptor-like factor 1 
IL21R                 0.018   interleukin 21 receptor precursor 
IL21R                 0.018   interleukin 21 receptor precursor 
IL21R                 0.018   interleukin 21 receptor precursor 
EPHA10                0.013   EPH receptor A10 isofom 3 
LEPR                  0.012   leptin receptor isoform 3 
LEPR                  0.012   leptin receptor isoform 2 
LEPR                  0.012   leptin receptor isoform 1 
IL12RB1               0.012   interleukin 12 receptor, beta 1 isoform 1 precursor [...
IL12RB1               0.012   interleukin 12 receptor, beta 1 isoform 2 precursor ...
CSF2RB                0.011   colony stimulating factor 2 receptor, beta precursor ...
IL5RA                 0.011   interleukin 5 receptor, alpha isoform 2 precursor [H...
IL5RA                 0.011   interleukin 5 receptor, alpha isoform 1 precursor [H...
IL5RA                 0.011   interleukin 5 receptor, alpha isoform 1 precursor [H...
IL5RA                 0.011   interleukin 5 receptor, alpha isoform 3 precursor [H...
IL5RA                 0.011   interleukin 5 receptor, alpha isoform 3 precursor [H...
IL5RA                 0.011   interleukin 5 receptor, alpha isoform 2 precursor [H...
CSF3R                 0.011   colony stimulating factor 3 receptor isoform d precu...
CSF3R                 0.011   colony stimulating factor 3 receptor isoform c precu...
CSF3R                 0.011   colony stimulating factor 3 receptor isoform a precur...
IL12RB2               0.011   interleukin 12 receptor, beta 2 precursor 
GHR                   0.011   growth hormone receptor precursor 
SORL1                 0.009   sortilin-related receptor containing LDLR class A rep...
EBI3                  0.008   Epstein-Barr virus induced 3 precursor 
MYOM3                 0.008   myomesin family, member 3 
CNTFR                 0.008   ciliary neurotrophic factor receptor preproprotein [...
CNTFR                 0.008   ciliary neurotrophic factor receptor preproprotein [H...
IL7R                  0.007   interleukin 7 receptor precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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