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Search of human proteins with 50301240
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50301240 exosome component 10 isoform 1 [Homo sapiens]
(885 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50301240 exosome component 10 isoform 1 [Homo sapiens] 1786 0.0
gi|4505917 exosome component 10 isoform 2 [Homo sapiens] 1722 0.0
gi|104526627 triadin [Homo sapiens] 49 2e-05
gi|145279204 exonuclease 3'-5' domain containing 3 [Homo sapiens] 44 5e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 41 0.004
gi|4506467 radixin [Homo sapiens] 40 0.010
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 40 0.013
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 39 0.016
gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens] 39 0.021
gi|239748665 PREDICTED: hypothetical protein [Homo sapiens] 39 0.021
gi|239742690 PREDICTED: hypothetical protein [Homo sapiens] 39 0.021
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens] 39 0.028
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 38 0.036
gi|110349719 titin isoform N2-A [Homo sapiens] 38 0.048
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 38 0.048
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 38 0.048
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 38 0.048
gi|154354979 myosin X [Homo sapiens] 38 0.048
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 37 0.062
gi|68508961 centromere protein C 1 [Homo sapiens] 37 0.11
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 37 0.11
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 36 0.14
gi|157738619 smoothelin-like 1 [Homo sapiens] 36 0.14
gi|110349717 titin isoform novex-2 [Homo sapiens] 36 0.18
gi|110349713 titin isoform novex-1 [Homo sapiens] 36 0.18
gi|110349715 titin isoform N2-B [Homo sapiens] 36 0.18
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 36 0.18
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 36 0.18
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 36 0.18
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 36 0.18
>gi|50301240 exosome component 10 isoform 1 [Homo sapiens]
Length = 885
Score = 1786 bits (4625), Expect = 0.0
Identities = 885/885 (100%), Positives = 885/885 (100%)
Query: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
Sbjct: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
Query: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
Sbjct: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
Query: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
Sbjct: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
Query: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
Sbjct: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
Query: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
Sbjct: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
Query: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
Sbjct: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
Query: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
Sbjct: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
Query: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
Sbjct: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
Query: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
Sbjct: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
Query: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
Sbjct: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
Query: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
Sbjct: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
Query: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI 720
FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
Sbjct: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI 720
Query: 721 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 780
SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
Sbjct: 721 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 780
Query: 781 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 840
ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
Sbjct: 781 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 840
Query: 841 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 885
DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
Sbjct: 841 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 885
>gi|4505917 exosome component 10 isoform 2 [Homo sapiens]
Length = 860
Score = 1722 bits (4459), Expect = 0.0
Identities = 860/885 (97%), Positives = 860/885 (97%), Gaps = 25/885 (2%)
Query: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
Sbjct: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
Query: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
Sbjct: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
Query: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
Sbjct: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
Query: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
Sbjct: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
Query: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
Sbjct: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
Query: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
Sbjct: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
Query: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
Sbjct: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
Query: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
Sbjct: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
Query: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
Sbjct: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
Query: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
Sbjct: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
Query: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
Sbjct: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
Query: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI 720
FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRM I
Sbjct: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRM-------------------------I 695
Query: 721 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 780
SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
Sbjct: 696 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 755
Query: 781 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 840
ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
Sbjct: 756 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 815
Query: 841 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 885
DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
Sbjct: 816 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 860
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 15/176 (8%)
Query: 697 PSLGHRAPVSQAAKFDP-STKIYEISNRWKLAQVQV----QKDSKEAVKKKAAEQTAARE 751
P++ P QA++ P S + E K A+ +V +K KE +KKK+ ++TA
Sbjct: 288 PAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDV 347
Query: 752 QAKEACKAAAEQAISVRQQVVLENAAKKRE-----RATSDPRTTEQKQEKKRLKISKKPK 806
+ KE KA+ + +V+ + + AAKK E + T P EQ + KK+ K K +
Sbjct: 348 EKKEPGKASETKQGTVK--IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVE 405
Query: 807 DPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSV 862
+ P+KE + S KA +K ++ + K P K+ K ++Q +
Sbjct: 406 PAKSPKKEHSV--PSDKQVKAKTERAKEEIGA-VSIKKAVPGKKEEKTTKTVEQEI 458
Score = 30.8 bits (68), Expect = 5.8
Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 10/112 (8%)
Query: 735 SKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQ 794
+K K+K + RE+ K KA ++ I +++ + AK++++A +T E+ +
Sbjct: 160 TKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKA----KTAEKSE 215
Query: 795 E--KKRLKISKKPKDPEPPEK----EFTPYDYSQSDFKAFAGNSKSKVSSQF 840
E KK +K K+ K + K + TP + + K A SK + Q+
Sbjct: 216 EKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQY 267
>gi|145279204 exonuclease 3'-5' domain containing 3 [Homo sapiens]
Length = 876
Score = 44.3 bits (103), Expect = 5e-04
Identities = 47/201 (23%), Positives = 88/201 (43%), Gaps = 32/201 (15%)
Query: 282 PIEETPCHFISSLDELVELNEKLLNC-QEFAVDLEHHSYRSFLGLT--CLMQISTRTEDF 338
PI H ++S ++L LL C Q VD+E G L+Q++ F
Sbjct: 367 PIPRENVHLLASWEDLTRHEGALLQCHQVVGVDVEWTPVFVAGGRPRPSLLQVAVEGHVF 426
Query: 339 IIDTLEL---------RSDMYILNESLTDPAIVKVFHGADSDIEWL----------QKDF 379
++D L L ++ ++ + L+DP+I K+ +G D++ L +K
Sbjct: 427 LLDVLALSQPPTGQGAQAFSRLVAQLLSDPSITKLGYGMVGDLQKLGTSCPALAHVEKQI 486
Query: 380 GLYVVNMFDTHQAARLLNLGRHSLDH---------LLKLYCNVDSNKQYQLADWRIRPLP 430
L +++ H+ R+ ++ ++D L++ +K QL++W RPL
Sbjct: 487 -LGGMDLLLVHRQMRVASVPAPAVDRARELRGLSLLVQQVLGTALDKTQQLSNWDRRPLC 545
Query: 431 EEMLSYARDDTHYLLYIYDKM 451
EE + YA D + LL ++ +
Sbjct: 546 EEQVIYAAADAYCLLEVHQAL 566
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 41.2 bits (95), Expect = 0.004
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 727 AQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRE----- 781
A+V+V++D+K K + A++ +AKE K A ++ + ++ E AKK E
Sbjct: 912 AKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKT 971
Query: 782 --RATSDPRT-----TEQKQEKKRLKISKKPKDPEPPEK 813
+A D +T ++ K EK S KD +PPEK
Sbjct: 972 EAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Score = 38.9 bits (89), Expect = 0.021
Identities = 45/207 (21%), Positives = 81/207 (39%), Gaps = 25/207 (12%)
Query: 664 PSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISNR 723
P+ E++K P + +K E ++P + P ++P + AK
Sbjct: 553 PAKEEAKSPPEAKSPEK-----EEAKSPAEVKSPEKA-KSPAKEEAKSP----------- 595
Query: 724 WKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERA 783
A+ + + +K VK++A A+ KE K+ AE + + + AK E+A
Sbjct: 596 ---AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA 652
Query: 784 TSDPRTTEQKQEKKRLKISKKPKDPE----PPEKEFTPYDYSQSDFKAFAGNSKSKVSSQ 839
S + + EK + + + K PE P + E + ++S K A S K S
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA-KSPEKAKSP 711
Query: 840 FDPNKQTPSGKKCIAAKKIKQSVGNKS 866
++P K ++ K KS
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKS 738
Score = 37.0 bits (84), Expect = 0.081
Identities = 38/175 (21%), Positives = 67/175 (38%), Gaps = 12/175 (6%)
Query: 702 RAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAA 761
++PV AK K + V+ + S E K E+ + E+AK K A
Sbjct: 667 KSPVKAEAKSPEKAK----------SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 762 EQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYS 821
+ + V E AK E+A S + + EK + K D + PE + + +
Sbjct: 717 KSPEKAKSPVKEE--AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 822 QSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDR 876
+S F +KS V + ++ S K A K+ + + P + ++
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Score = 36.6 bits (83), Expect = 0.11
Identities = 55/230 (23%), Positives = 88/230 (38%), Gaps = 26/230 (11%)
Query: 663 EPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISN 722
E + K P+ K + +S E + + S + P + A+ P+ K E +
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKA-KSPEKAKTLDVKSPEAKTPAKEEAR-SPADKFPEKAK 786
Query: 723 RWKLAQVQVQKDSKEAVKKKAAEQTAAREQA---KEACKAAAEQAISVRQQVVLENAAK- 778
+ V+ + S E K E A E+ KE K+ ++ ++ V E K
Sbjct: 787 ----SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 779 KRERATSDPRTTEQKQEKKR---LKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSK 835
+ E+A + P+T E+K KK K + KPK E E S+ + K K K
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Query: 836 VSSQFDPNKQTPS----------GKKCIAAKKIKQSVGNKSMSFPTGKSD 875
V + P K+ P+ +K AKK K S P K +
Sbjct: 903 VPT---PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
Score = 30.8 bits (68), Expect = 5.8
Identities = 32/129 (24%), Positives = 49/129 (37%), Gaps = 7/129 (5%)
Query: 729 VQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRE--RATSD 786
V+ K+SK KK+ AE ++ A E + + E A K+ + +A
Sbjct: 882 VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 787 PRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKV-----SSQFD 841
+ E+K+ K +K+ K +P EK T + D SK K SS D
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD 1001
Query: 842 PNKQTPSGK 850
P K
Sbjct: 1002 QKDSKPPEK 1010
Score = 30.0 bits (66), Expect = 9.9
Identities = 54/283 (19%), Positives = 113/283 (39%), Gaps = 30/283 (10%)
Query: 607 FGPHDCSHAPPDGYPIIPT-SGSVPVQKQASLFPDEKEDNLLGTTCLI--------ATAV 657
FGP S P+G P IP+ S + V+ + + EK + T ++ T
Sbjct: 415 FGPIPFSL--PEGLPKIPSVSTHIKVKSEEKIKVVEKSEK---ETVIVEEQTEETQVTEE 469
Query: 658 ITLFNEPSA-EDSKKGPLTVAQKKAQNIMESFENP--FRMFLPSLGHRAPVSQAAKFDPS 714
+T E A E+ K +++A+ E ++P P ++PV + AK
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 715 TKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLE 774
K E + + S VK ++ A+E+AK +A + + + ++
Sbjct: 530 AKSPE----------KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK 579
Query: 775 NAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFA---GN 831
+ K + A + ++ + + ++ K K + P E + + ++S + +
Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK 639
Query: 832 SKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKS 874
S +K ++ ++P ++ + +K K V ++ S KS
Sbjct: 640 SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 40.0 bits (92), Expect = 0.010
Identities = 42/180 (23%), Positives = 77/180 (42%), Gaps = 17/180 (9%)
Query: 668 DSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISNRWKLA 727
+++K +A+K+ + I E L + + +Q + + K E+ K A
Sbjct: 324 ENEKKKREIAEKEKERIEREKEELMER-LKQIEEQTIKAQKELEEQTRKALELDQERKRA 382
Query: 728 QVQVQKDSKE---AVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRE--- 781
+ + ++ KE A + K+A A +Q K + AAE A + +LE A KK+E
Sbjct: 383 KEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEA 442
Query: 782 -----RATSDPRTTEQKQEKKRLKISKKPKDPEPP-----EKEFTPYDYSQSDFKAFAGN 831
+A + E+ +E+ + +S P P PP E E +D + ++ A N
Sbjct: 443 TEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSN 502
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 39.7 bits (91), Expect = 0.013
Identities = 36/171 (21%), Positives = 70/171 (40%), Gaps = 22/171 (12%)
Query: 719 EISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAK 778
E NR + + + ++D + +++ E+ E+ KE + E E
Sbjct: 409 ERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEW----------ERERA 458
Query: 779 KRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSS 838
KR+ R ++++E+++ K KP+ P+PP ++ P A G +
Sbjct: 459 KRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP----PKKEAATTGPQVKRADE 514
Query: 839 QFDPNKQTPSGKKCI--------AAKKIKQSVGNKSMSFPTGKSDRGFRYN 881
DP +++ S KK + A ++ K S + S S + S R Y+
Sbjct: 515 WKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYS 565
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 39.3 bits (90), Expect = 0.016
Identities = 34/159 (21%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Query: 706 SQAAKFDPSTKIYEISNRW-----KLAQVQVQKDSKEAVKK-KAAEQTAAREQAKEACKA 759
S + F ST + I+ ++ + ++++Q+D + K+ K + +E+ KE K
Sbjct: 307 SSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKR 366
Query: 760 AAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYD 819
A E+A +++ E K++ER + ++K EK+RLK ++ + E E +
Sbjct: 367 AKEEAKKKKEE---EKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKR 423
Query: 820 YSQSDFKAFAGNSKSKVS----SQFDPNKQTPSGKKCIA 854
+ + + + K ++F +TP K +A
Sbjct: 424 KKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLA 462
Score = 35.0 bits (79), Expect = 0.31
Identities = 24/111 (21%), Positives = 50/111 (45%), Gaps = 21/111 (18%)
Query: 733 KDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQ 792
K +KE KKK E+ +E+ + + E+ + +Q++ E +++E + +
Sbjct: 365 KRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRK 424
Query: 793 KQEKKRL---------------KISKKPKDPEPPEK------EFTPYDYSQ 822
K+E+KRL + +KPK P+ P+ +F P++ +
Sbjct: 425 KEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKE 475
>gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens]
Length = 2002
Score = 38.9 bits (89), Expect = 0.021
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 701 HRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAA 760
H P+ + + D + + + +QV + V+ A R++ EA KAA
Sbjct: 1416 HVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAA 1475
Query: 761 AEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLK-----------ISKKPKDPE 809
AE+ S LEN++ K E+ S P T+Q + + K + ++ + P+
Sbjct: 1476 AEKLSS------LENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQ 1529
Query: 810 PPEKE 814
P +K+
Sbjct: 1530 PLQKQ 1534
>gi|239748665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 223
Score = 38.9 bits (89), Expect = 0.021
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 267 PADAVLQKP-QPQLYRPIEETPCHFISS-----------------LDELVELNEKLLNCQ 308
PA L P Q L+ P ETP F++S L L+ + +L Q
Sbjct: 70 PAQGSLLSPAQVGLFLPRRETPIPFVTSNKDIPAASPSCATSCYLLPSLLPHSSAILRNQ 129
Query: 309 EFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNES 355
++DL S+RS LGL CL+++ T ++ TL R + I+ ++
Sbjct: 130 TASMDLGRQSWRSSLGLLCLVELITAVA-CLLKTLRSRGQLTIVEQN 175
>gi|239742690 PREDICTED: hypothetical protein [Homo sapiens]
Length = 223
Score = 38.9 bits (89), Expect = 0.021
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 267 PADAVLQKP-QPQLYRPIEETPCHFISS-----------------LDELVELNEKLLNCQ 308
PA L P Q L+ P ETP F++S L L+ + +L Q
Sbjct: 70 PAQGSLLSPAQVGLFLPRRETPIPFVTSNKDIPAASPSCATSCYLLPSLLPHSSAILRNQ 129
Query: 309 EFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNES 355
++DL S+RS LGL CL+++ T ++ TL R + I+ ++
Sbjct: 130 TASMDLGRQSWRSSLGLLCLVELITAVA-CLLKTLRSRGQLTIVEQN 175
>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
Length = 1989
Score = 38.5 bits (88), Expect = 0.028
Identities = 27/131 (20%), Positives = 60/131 (45%), Gaps = 15/131 (11%)
Query: 721 SNRWKLAQVQVQKDSKEAVKKKAAEQ----TAAREQAKEACKAAAEQAISVRQ----QVV 772
S +W+ + QV K+SKE + K Q T+ + + + A+QA+ +Q + +
Sbjct: 383 SKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKL 442
Query: 773 LENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNS 832
+ ++R++ + E+++ +KR + +K +D E+++ + F G
Sbjct: 443 QQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQY-------NRFMKLVGGK 495
Query: 833 KSKVSSQFDPN 843
+ S DP+
Sbjct: 496 RRSRSKSSDPD 506
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 38.1 bits (87), Expect = 0.036
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Query: 709 AKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQA--IS 766
A+ PS +I S R K + ++ +E+ + E KE K E+ ++
Sbjct: 165 AEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVT 224
Query: 767 VRQQVVLENAAKKRERATSDPRT--TEQKQEKKRLKISKKPKDPEPPEK 813
R++V A++ ERA S RT E++ EK+ ++ + K+P P +K
Sbjct: 225 SRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQK 273
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 37.7 bits (86), Expect = 0.048
Identities = 66/299 (22%), Positives = 114/299 (38%), Gaps = 76/299 (25%)
Query: 539 KIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLK-SEVAAG--VKKSGP 595
K+ +PK+P+ A VP + ++ + E + + + E+P K EV +++
Sbjct: 10733 KVPLVVPKKPEAPPA---KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPA 10789
Query: 596 LPSAERLENVLFGPHDCSHAPPDGYP----IIPTSGSVPVQKQASLFPDEKEDNLLGTTC 651
+P ER E+ PP+ Y I P P +++ +E+E +
Sbjct: 10790 VPVPERAES----------PPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAV 10839
Query: 652 ------LIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPV 705
+I + + +P A K + + + ++E P L R P
Sbjct: 10840 PEEPKKIIPEKKVPVIKKPEAPPPK-------EPEPEKVIEK---------PKLKPRPPP 10883
Query: 706 SQAA--KFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQA---------- 753
A K D KI+++ K KKK E+ E+
Sbjct: 10884 PPPAPPKEDVKEKIFQL---------------KAIPKKKVPEKPQVPEKVELTPLKVPGG 10928
Query: 754 -KEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPP 811
K+ K E+ +++VVL++ +KR P E K E K+L+ KKP PEPP
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKR------PEEEEPKVEPKKLEKVKKPAVPEPP 10981
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 37.7 bits (86), Expect = 0.048
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 713 PSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQA--ISVRQQ 770
PS +I S R K + ++ +E+ + E KE K E+ ++ R++
Sbjct: 153 PSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRER 212
Query: 771 VVLENAAKKRERATSDPRT--TEQKQEKKRLKISKKPKDPEPPEK 813
V A++ ERA S RT E++ EK+ ++ + K+P P +K
Sbjct: 213 VARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQK 257
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 37.7 bits (86), Expect = 0.048
Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Query: 736 KEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQE 795
K+ KKK E+T E+ +E + ++ R++ E KK+ + T + E++++
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 796 KKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAA 855
K++ K KK ++ E E+E + + + K K K + ++ K+
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 856 KK 857
KK
Sbjct: 121 KK 122
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 37.7 bits (86), Expect = 0.048
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 774 ENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSK 833
E KKR +A DP+ ++ +EK K+PK+P+ P+ P + + K K
Sbjct: 640 EKKKKKRSKAKKDPKEPKEPKEK------KEPKEPKTPKAPKIPKEPKEKKAKTATPKPK 693
Query: 834 -SKVSSQFDPNKQTPSGKKCIAAKKIKQS 861
SK SS P+ + + KK + K + S
Sbjct: 694 SSKKSSNKKPDSEASALKKKVNKGKTEGS 722
Score = 33.1 bits (74), Expect = 1.2
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 5/89 (5%)
Query: 791 EQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDP----NKQT 846
E+K++KKR K K PK+P+ P+++ P + K K + P +K++
Sbjct: 639 EEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKS 698
Query: 847 PSGKKCIAAKKIKQSVGNKSMSFPTGKSD 875
+ K A +K+ V NK + + SD
Sbjct: 699 SNKKPDSEASALKKKV-NKGKTEGSENSD 726
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 37.7 bits (86), Expect = 0.048
Identities = 34/143 (23%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 723 RWKLAQVQVQKDSK---EAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKK 779
R LA+ + Q++ K E KKK E+ RE+ + + A+Q R+Q LE K
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS 868
Query: 780 RERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQ 839
++ A +QK+ K+ +I + K+ E ++ + S ++ S K+ +
Sbjct: 869 QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTE------ASLQKLQER 922
Query: 840 FDPNKQTPSGKKCIAAKKIKQSV 862
D + + C AA++ +S+
Sbjct: 923 RDQELRRLEEEACRAAQEFLESL 945
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 37.4 bits (85), Expect = 0.062
Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Query: 736 KEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQE 795
K+A KK+ ++ K++ K A + + ++E K++ A P + + E
Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170
Query: 796 KKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTP 847
+ + S +PE + + SQ D K + NSK K +++F K P
Sbjct: 171 QSKKSKSSSETNPESQNSKTVSKNCSQKD-KKDSKNSK-KTNTEFLHTKNNP 220
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 21/168 (12%)
Query: 707 QAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAR-EQAKEACKAAAEQAI 765
++ FD + Y +N K ++ K +K+ KK A + + A E +K+A K + +
Sbjct: 257 ESINFDAWLRNYSQNNS-KNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKK 315
Query: 766 SVRQQ-----VVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEP-PEKEFTPYD 819
+V++ V + + E S + K++KK+LK K KD + PE D
Sbjct: 316 NVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPEST----D 371
Query: 820 YSQSDFKAFAGNSKS-KVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKS 866
D K +S++ K +S+ D K+ AKKI S ++S
Sbjct: 372 TESGDAKDARNDSRNLKKASKNDDKKKD--------AKKITFSTDSES 411
Score = 30.4 bits (67), Expect = 7.6
Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 36/161 (22%)
Query: 721 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 780
S + K + + +KDSK+ KKK A++ A + +
Sbjct: 454 SKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEME-------------------------- 487
Query: 781 ERATSDPRTTEQKQEKKRLKISKKP-KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQ 839
SD + K+ K K SKK K + E T ++ +S F ++K K S
Sbjct: 488 ----SDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDT 543
Query: 840 FDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTG-KSDRGFR 879
G K KKI +S G + S G +S RGFR
Sbjct: 544 ESEESLYKPGAK----KKIDESDGTSANSKMEGLESKRGFR 580
>gi|68508961 centromere protein C 1 [Homo sapiens]
Length = 943
Score = 36.6 bits (83), Expect = 0.11
Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Query: 735 SKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQ---QVVLENAAKKRERATSDPRTTE 791
SK A K +++T ++Q ++ AE+ + V Q + + + + E + R E
Sbjct: 404 SKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNME 463
Query: 792 QKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKV 836
+ +E +SKK P +K T D +S K F+ SK+K+
Sbjct: 464 EHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKL 508
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 36.6 bits (83), Expect = 0.11
Identities = 32/172 (18%), Positives = 70/172 (40%), Gaps = 6/172 (3%)
Query: 700 GHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKA 759
G +A K + + K +R KL K KKK +++ + + +
Sbjct: 54 GSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDS 113
Query: 760 AAEQAISVRQQVVLENAAKKRERAT--SDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTP 817
++ + S ++ KK++ + S +T + + + + + KK K + EKE
Sbjct: 114 SSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDV 173
Query: 818 YDYSQSDFKAFAG----NSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNK 865
S+ K++ +S+S S ++ + Q ++C ++ K+ V K
Sbjct: 174 RSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKK 225
Score = 34.3 bits (77), Expect = 0.53
Identities = 29/135 (21%), Positives = 62/135 (45%), Gaps = 10/135 (7%)
Query: 734 DSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQK 793
DS++ KK+ + + ++ ++ +++ ++ S ++ V K+++ + D E +
Sbjct: 119 DSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESV------KKKKKSKD----ETE 168
Query: 794 QEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCI 853
+EK +SKK K P +K + S+SD++ K + + + K+ KK
Sbjct: 169 KEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK 228
Query: 854 AAKKIKQSVGNKSMS 868
KK + KS S
Sbjct: 229 QHKKHSKKKKKKSGS 243
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 36.2 bits (82), Expect = 0.14
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 204 IKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELN 263
+K QKP + L E E ++ +D+ +P L D +++Q+ +Q H Y+Y N
Sbjct: 1298 VKNEEQKPTKEPL--EVSEWNKNSSKDVKIPDTLQDQLNEQQKRQPLSVSDRHVYKYRCN 1355
Query: 264 HFTPADAVLQKPQ 276
H + A +QK Q
Sbjct: 1356 HCSLAFKTMQKLQ 1368
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 36.2 bits (82), Expect = 0.14
Identities = 48/244 (19%), Positives = 98/244 (40%), Gaps = 48/244 (19%)
Query: 641 EKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLG 700
EKE+ +G+ + T +EP + K+ L ++KA+ + P G
Sbjct: 118 EKEETTVGSQEMTGRKEETK-SEPKEAEEKESTLASEKQKAEE---------KEAKPESG 167
Query: 701 HRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAA 760
+A + K +P + E +D+K A +++ ++ + KE KA
Sbjct: 168 QKADANDRDKPEPKATVEE-------------EDAKTASQEETGQRKECSTEPKE--KAT 212
Query: 761 AEQAISVRQQVVLENAAKKRERATSDPRTTEQKQE-----KKRLKISKKPKDPEPPEKEF 815
E+A + Q+ V+E+ AK ++P+ + K+E K+ ++ +D E E
Sbjct: 213 DEEAKAESQKAVVEDEAK------AEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPG- 265
Query: 816 TPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGK-----------KCIAAKKIKQSVGN 864
+P + + D + + S + ++P+G+ C+A+ + S
Sbjct: 266 SPSEEQEQDVEKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASE 325
Query: 865 KSMS 868
S S
Sbjct: 326 SSPS 329
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 35.8 bits (81), Expect = 0.18
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Query: 754 KEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPP 811
K+ K E+ +++VVL++ +KR P E K E K+L+ KKP PEPP
Sbjct: 4625 KKVRKLLPERKPEPKEEVVLKSVLRKR------PEEEEPKVEPKKLEKVKKPAVPEPP 4676
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 35.8 bits (81), Expect = 0.18
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Query: 754 KEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPP 811
K+ K E+ +++VVL++ +KR P E K E K+L+ KKP PEPP
Sbjct: 4558 KKVRKLLPERKPEPKEEVVLKSVLRKR------PEEEEPKVEPKKLEKVKKPAVPEPP 4609
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 35.8 bits (81), Expect = 0.18
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Query: 754 KEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPP 811
K+ K E+ +++VVL++ +KR P E K E K+L+ KKP PEPP
Sbjct: 4433 KKVRKLLPERKPEPKEEVVLKSVLRKR------PEEEEPKVEPKKLEKVKKPAVPEPP 4484
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 769 QQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQS--DFK 826
Q ++ ++ K R RA + T+E QE + + +KP++P+ E E + D + D++
Sbjct: 1392 QDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK-DEVEVSDDDEKEPEVDYR 1450
Query: 827 AFAGNSKSKVSSQFDPNKQTPSGK 850
N++ KVS +D ++ SGK
Sbjct: 1451 TVTINTEQKVSDFYDIEERLGSGK 1474
Score = 33.5 bits (75), Expect = 0.90
Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 8/131 (6%)
Query: 732 QKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTE 791
Q D ++ + KK + +T + + KE + ++++QV + +++ ER P+ +
Sbjct: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEE-ERKVHSPQQVD 952
Query: 792 QKQEKKRLKISKKP-KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGK 850
+ + SK P + PP K TP DF++ G K + + +T + K
Sbjct: 953 FRSVLAKKGTSKTPVPEKVPPPKPATP------DFRSVLGGKKKLPAENGSSSAETLNAK 1006
Query: 851 KCIAAKKIKQS 861
++K + +
Sbjct: 1007 AVESSKPLSNA 1017
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 769 QQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQS--DFK 826
Q ++ ++ K R RA + T+E QE + + +KP++P+ E E + D + D++
Sbjct: 1392 QDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK-DEVEVSDDDEKEPEVDYR 1450
Query: 827 AFAGNSKSKVSSQFDPNKQTPSGK 850
N++ KVS +D ++ SGK
Sbjct: 1451 TVTINTEQKVSDFYDIEERLGSGK 1474
Score = 33.5 bits (75), Expect = 0.90
Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 8/131 (6%)
Query: 732 QKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTE 791
Q D ++ + KK + +T + + KE + ++++QV + +++ ER P+ +
Sbjct: 894 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEE-ERKVHSPQQVD 952
Query: 792 QKQEKKRLKISKKP-KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGK 850
+ + SK P + PP K TP DF++ G K + + +T + K
Sbjct: 953 FRSVLAKKGTSKTPVPEKVPPPKPATP------DFRSVLGGKKKLPAENGSSSAETLNAK 1006
Query: 851 KCIAAKKIKQS 861
++K + +
Sbjct: 1007 AVESSKPLSNA 1017
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 769 QQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQS--DFK 826
Q ++ ++ K R RA + T+E QE + + +KP++P+ E E + D + D++
Sbjct: 1323 QDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK-DEVEVSDDDEKEPEVDYR 1381
Query: 827 AFAGNSKSKVSSQFDPNKQTPSGK 850
N++ KVS +D ++ SGK
Sbjct: 1382 TVTINTEQKVSDFYDIEERLGSGK 1405
Score = 33.5 bits (75), Expect = 0.90
Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 8/131 (6%)
Query: 732 QKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTE 791
Q D ++ + KK + +T + + KE + ++++QV + +++ ER P+ +
Sbjct: 825 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEE-ERKVHSPQQVD 883
Query: 792 QKQEKKRLKISKKP-KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGK 850
+ + SK P + PP K TP DF++ G K + + +T + K
Sbjct: 884 FRSVLAKKGTSKTPVPEKVPPPKPATP------DFRSVLGGKKKLPAENGSSSAETLNAK 937
Query: 851 KCIAAKKIKQS 861
++K + +
Sbjct: 938 AVESSKPLSNA 948
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 769 QQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQS--DFK 826
Q ++ ++ K R RA + T+E QE + + +KP++P+ E E + D + D++
Sbjct: 1323 QDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK-DEVEVSDDDEKEPEVDYR 1381
Query: 827 AFAGNSKSKVSSQFDPNKQTPSGK 850
N++ KVS +D ++ SGK
Sbjct: 1382 TVTINTEQKVSDFYDIEERLGSGK 1405
Score = 33.5 bits (75), Expect = 0.90
Identities = 27/131 (20%), Positives = 58/131 (44%), Gaps = 8/131 (6%)
Query: 732 QKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTE 791
Q D ++ + KK + +T + + KE + ++++QV + +++ ER P+ +
Sbjct: 825 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEE-ERKVHSPQQVD 883
Query: 792 QKQEKKRLKISKKP-KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGK 850
+ + SK P + PP K TP DF++ G K + + +T + K
Sbjct: 884 FRSVLAKKGTSKTPVPEKVPPPKPATP------DFRSVLGGKKKLPAENGSSSAETLNAK 937
Query: 851 KCIAAKKIKQS 861
++K + +
Sbjct: 938 AVESSKPLSNA 948
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,201,841
Number of Sequences: 37866
Number of extensions: 1694037
Number of successful extensions: 7383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 186
Number of HSP's that attempted gapping in prelim test: 6598
Number of HSP's gapped (non-prelim): 879
length of query: 885
length of database: 18,247,518
effective HSP length: 111
effective length of query: 774
effective length of database: 14,044,392
effective search space: 10870359408
effective search space used: 10870359408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.