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Search of human proteins with 50083281
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50083281 KIAA1853 protein [Homo sapiens]
(611 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50083281 KIAA1853 protein [Homo sapiens] 1204 0.0
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 210 4e-54
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 167 3e-41
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 119 8e-27
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 117 4e-26
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 105 9e-23
gi|50962882 G patch domain containing 8 [Homo sapiens] 101 2e-21
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 100 7e-21
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 96 1e-19
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 90 5e-18
gi|60097902 filaggrin [Homo sapiens] 90 7e-18
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 89 1e-17
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 86 1e-16
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 86 1e-16
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 84 4e-16
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 84 5e-16
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 83 6e-16
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 83 8e-16
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 83 8e-16
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 82 1e-15
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 82 1e-15
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 79 9e-15
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 79 9e-15
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 79 1e-14
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 79 1e-14
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 79 1e-14
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 79 1e-14
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 77 6e-14
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 76 8e-14
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 76 8e-14
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 1204 bits (3116), Expect = 0.0
Identities = 611/611 (100%), Positives = 611/611 (100%)
Query: 1 MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPS 60
MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPS
Sbjct: 1 MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPS 60
Query: 61 EKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKR 120
EKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKR
Sbjct: 61 EKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKR 120
Query: 121 RRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKS 180
RRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKS
Sbjct: 121 RRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKS 180
Query: 181 HRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSR 240
HRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSR
Sbjct: 181 HRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSR 240
Query: 241 PPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTS 300
PPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTS
Sbjct: 241 PPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTS 300
Query: 301 SARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG 360
SARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG
Sbjct: 301 SARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG 360
Query: 361 FQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSR 420
FQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSR
Sbjct: 361 FQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSR 420
Query: 421 STSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER 480
STSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER
Sbjct: 421 STSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER 480
Query: 481 ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSS 540
ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSS
Sbjct: 481 ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSS 540
Query: 541 SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSY 600
SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSY
Sbjct: 541 SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSY 600
Query: 601 SSADSYSSTRR 611
SSADSYSSTRR
Sbjct: 601 SSADSYSSTRR 611
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 210 bits (534), Expect = 4e-54
Identities = 196/538 (36%), Positives = 247/538 (45%), Gaps = 79/538 (14%)
Query: 90 RGHSASHDKDLTPPPSSRGKKKKK---KSTRKKRRRSSSYS---PSPVKKKKKKSSKKHK 143
RG+ H + P + KKKKK + +RKKRR S S SP++KKKK S KKH+
Sbjct: 152 RGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKK-SVKKHR 210
Query: 144 RRRSFS---KKRRHSSSSPKSKRRDEKRHKKQ--SRSRPRKSHRHRHHRCPSRSQSSESR 198
R RS S +KRRH S S K KR+++ + KK+ + S R+SHRH S S SS
Sbjct: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYS 270
Query: 199 PSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVI 258
S SR SP+ + R+ S+R S + SP P + G G
Sbjct: 271 DSRSPSR---LSPKHRDEGRKTGSQRSSGS---RSPSPSGGSGWGSPQRNGGSGQRSGAH 324
Query: 259 TG-SGSAADLFTKTASPLTTSRGRSQEY-----DSGNDTSSPPSTQTSSARSRGQEKGSP 312
G GSA K +SP R ++ G ++ SP S +S R G
Sbjct: 325 GGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRG-----GRA 379
Query: 313 SGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVK 372
+GG + R ++ S+P+ +G +P +
Sbjct: 380 AGGAGRRRRRRRRRRRSRSSA---SAPRRRGRRRPRPAPP-------------------R 417
Query: 373 KSSLVPSTARSSPMKGCSRSSSYASTRSSS---HSSRSPNPRASPRYTQSRSTSSEKRSY 429
SS S ARSS G R + S H + P + STS ++
Sbjct: 418 GSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH 477
Query: 430 SRSPSYSSKSGKRS--PPSRSSRSRRSPSYSR--------YSPSRERDPK---YSEKDSQ 476
R KS RS P RS S RSPS SR +SPSR PK +KD +
Sbjct: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE 537
Query: 477 QRERE------RARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSL 530
R R RARRR RSYSP+RKRRRDSPS +E RRITSARKRPIPYYRPSPSSS S
Sbjct: 538 GRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSC 597
Query: 531 SSTSSWYSSSSSRSASRSYSRSRSRSRSR-RRSRTRTSSSSSSRSPSPGSRSRSRSRS 587
S S + + S SRS S +S SRS RSRTR S SR+PSP SRS S S
Sbjct: 598 LS-SDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTR----SPSRTPSPSYHSRSSSES 650
Score = 82.8 bits (203), Expect = 8e-16
Identities = 116/373 (31%), Positives = 153/373 (41%), Gaps = 72/373 (19%)
Query: 299 TSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRG-RE 357
+SSA ++K GG +SR+ + S S + + K + G R
Sbjct: 161 SSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRR 220
Query: 358 SRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSS--SHSSRSPNP-RASP 414
R +S +C +K+ SP + R SS +S S SH S S +P R SP
Sbjct: 221 KRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSP 280
Query: 415 RYT-QSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSY-----SRYSPS----- 463
++ + R T S++ S SRSPS S SG SP +RS ++ S +SP
Sbjct: 281 KHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSS 340
Query: 464 ---RERD----------------PKYSEKDSQQRERERA-----RRRRRSYSPMRKRRRD 499
R RD P S Q RA RRRRR R+RRR
Sbjct: 341 PSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRR-----RRRRRR 395
Query: 500 SPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA---------SRSYS 550
S S A R R+RP P P SS SLS S S S R A R +
Sbjct: 396 SRSSASAPR-RRGRRRPRP--APPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452
Query: 551 RSRSRSRSRR-RSRTRTSS--------------SSSSRSPSPGSRSRSRSRSRSRSRSRS 595
R++ R R+R ++S SSSRSP P RS S SRS S+SRSRS
Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512
Query: 596 -QSRSYSSADSYS 607
+ R +S + S S
Sbjct: 513 AEKRPHSPSRSPS 525
Score = 52.4 bits (124), Expect = 1e-06
Identities = 74/271 (27%), Positives = 91/271 (33%), Gaps = 55/271 (20%)
Query: 389 CSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSS--------KSG 440
C R T+ S SS SP P+ + S +KR S S KS
Sbjct: 147 CYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSV 206
Query: 441 KRSPPSRS-SRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS---------- 489
K+ RS S SRR + S +R K EK E R R S
Sbjct: 207 KKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLS 266
Query: 490 --YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYS--------- 538
YS R R SP H + R T ++ R S S S S S S W S
Sbjct: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQ-------RSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
Query: 539 --------SSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRS--- 587
S+ S S R R + + T + SPSP S S+ R
Sbjct: 320 RSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRA 379
Query: 588 -------RSRSRSRSQSRSYSSADSYSSTRR 611
R R R R +SRS +SA RR
Sbjct: 380 AGGAGRRRRRRRRRRRSRSSASAPRRRGRRR 410
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 167 bits (422), Expect = 3e-41
Identities = 167/548 (30%), Positives = 239/548 (43%), Gaps = 57/548 (10%)
Query: 92 HSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKK 151
+S + + P+ + KKKKKK R +R SSS P +++KK S KK R S SKK
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSS----PRRERKKSSKKKKHRSESESKK 226
Query: 152 RRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSP 211
R+H S +PKSKR+ + + +K+SRS R H RS S++S SS SR R RS
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH----RSTSADSASSSDTSRSRSRS- 281
Query: 212 EEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKT 271
K A + R PS G A G+ S +
Sbjct: 282 ----------------AAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTST----QRP 321
Query: 272 ASPLTTSRGRSQEY-DSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDS 330
+SP T ++ S Y D D +T+ S + R P E + G+
Sbjct: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381
Query: 331 GNSFTTSSPQN---KGAMLENLSPTSRGRE-----SRGFQSPCLECAEVKK-SSLVPSTA 381
+ + P N + + + SP + S P + +V + +S P +
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441
Query: 382 RSSPMKGCSRS-SSYASTRSSSH------SSRSPNPRASPRYTQSRSTSSEKRSYSRSPS 434
+ +P G R SS ++++ SH S S P ++S +T+ RS SR+P+
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501
Query: 435 YSSKSGKRSPPSRSSRS------RRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRR 488
S RSP R SRS RSP S S +R +++Q+R R R+ RR R
Sbjct: 502 KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGR 561
Query: 489 SYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPS--PSSSGSLSSTSSWYSSSSSRSAS 546
S+S R S S ARR S + P S P+ S S T + S SR+ +
Sbjct: 562 SHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPA 621
Query: 547 RSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRS---RSRSRSRSQSRSYSSA 603
R SR+RS R R RSR+ S SRS +P R RSRSR+ R RSRSR+ +R +
Sbjct: 622 RRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRS 681
Query: 604 DSYSSTRR 611
S + RR
Sbjct: 682 RSRTPARR 689
Score = 135 bits (340), Expect = 1e-31
Identities = 173/618 (27%), Positives = 263/618 (42%), Gaps = 81/618 (13%)
Query: 17 RGTFKAVATPRPESIIVASITARKPLPRTEPQNNP------VVPAQD--GPSEKLGQH-L 67
RG + ++P P+++ + P PR+ ++P + P ++ G + Q +
Sbjct: 1475 RGRSECDSSPEPKAL------PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528
Query: 68 ATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYS 127
A PLG S R + +EL S + P S+ K + T ++R S S
Sbjct: 1529 ARTPLGQRS--RSGSSQELDVKPSASPQERSESDSSPDSKAKTR----TPLRQRSRSGSS 1582
Query: 128 P--------SPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRK 179
P SP + + S + + R+ + + S SSP+ K + ++SRS
Sbjct: 1583 PEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSS 1642
Query: 180 SHRHRHHRCPSRSQSSESRPSSCESRHRGR--SPEEGQKSR---RRHSRRCSKTLCKDSP 234
R S ++SS P + RG SPE KSR RR S R S L + +
Sbjct: 1643 KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKAR 1702
Query: 235 EAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSP 294
++ SR S + R + S S+ + K+ S SR R ++S
Sbjct: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS----SRRRR--------SASS 1750
Query: 295 PSTQTSSARSRGQEKGSPSG---GLSKSRELNSGNT---SDSGNSFTTSSPQNKGAMLEN 348
P T+T+S R R P G S+SR + T SG+S +TS + +
Sbjct: 1751 PRTKTTSRRGRSPSP-KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
Query: 349 LSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSP 408
++ RG +SP + ++R+S + RS + ++R S S SP
Sbjct: 1810 VTRRRRGGSGYHSRSPARQ-----------ESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858
Query: 409 NPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDP 468
P R S +T +RS SR+P S +R SR+S R S SR S +R R
Sbjct: 1859 APWKRSRSRASPAT--HRRSRSRTPLIS----RRRSRSRTSPVSRRRSRSRTSVTRRRSR 1912
Query: 469 KYSEKDSQQRERER----ARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSP 524
+ S++R R R RRR RS +P +RR S + RR + +R P+ R
Sbjct: 1913 SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRR--- 1969
Query: 525 SSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPS---PGSRS 581
S S + S S + +R SRSR+ +RRRSR+RTS + RS S P R
Sbjct: 1970 -SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRR 2028
Query: 582 RSRSRSRSRSRSRSQSRS 599
RSRSR+ R RS+SRS
Sbjct: 2029 RSRSRTPLLPRKRSRSRS 2046
Score = 130 bits (327), Expect = 4e-30
Identities = 196/644 (30%), Positives = 261/644 (40%), Gaps = 128/644 (19%)
Query: 65 QHLATEPLGTNSWERDKTCRELGA-----TRGHSASHDKDLTPP-----PSSRGKKKKKK 114
+ L+ PL NS+ R G G S+ +DL P + K++
Sbjct: 1315 KELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQ 1374
Query: 115 STRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSP--KSKRRDEKRHKKQ 172
STR SS SP V+K S++ S SSP + R R +
Sbjct: 1375 STRSSGHSSSELSPDAVEKAGMSSNQ--------------SISSPVLDAVPRTPSRERSS 1420
Query: 173 SRSRPRKSHRHRHHRCPSRSQSSESRP-----SSCESRHRGRSPEEGQKSRRRHSRRCSK 227
S S P + R PSR S S P S SRH G K R R +
Sbjct: 1421 SASSPEM--KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSR-GR 1477
Query: 228 TLCKDSPEAQS--------SRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPL--TT 277
+ C SPE ++ SR PS P L+ + +GS S+ D T +PL +
Sbjct: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
Query: 278 SRGRSQEYD----------SGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSR----ELN 323
G SQE D S +D+S +T + + GS SKSR
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR 1597
Query: 324 SGNTSD---------SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKS 374
SG++ + S + SSP+ K L SR S + P E + +S
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
Query: 375 SLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQ-------SRSTSSEKR 427
S + +G SRSS T+S + R + R+SP T+ SRS SS
Sbjct: 1658 SPEHPPKSRTARRG-SRSSPEPKTKSRTPPRRRSS-RSSPELTRKARLSRRSRSASSSPE 1715
Query: 428 SYSRSPSYSSKSGKRSPP-----SRSSRSRRSPSYSRY--------SPS-------RERD 467
+ SR+P +S S P SRSSR RRS S R SPS R R
Sbjct: 1716 TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRS 1775
Query: 468 PKYSEKDSQQRERERA---------RRRRRSYSPMRKRRRD-------SPSHLEARRITS 511
EK R R+R+ R+R RS S + +RRR SP+ E+ R +S
Sbjct: 1776 RSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS 1835
Query: 512 ARKRPIPYYRP-SPSSSGSLSSTSSWYSSSS---------SRSASRSYSRSRSRSR---- 557
R+R P S S S +S + W S S SRS + SR RSRSR
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895
Query: 558 SRRRSRTRTS-SSSSSRS-PSPGSRSRSRSRSRSRSRSRSQSRS 599
SRRRSR+RTS + SRS SP SR RSRSR+ +R RS+SR+
Sbjct: 1896 SRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRT 1939
Score = 127 bits (318), Expect = 4e-29
Identities = 160/586 (27%), Positives = 250/586 (42%), Gaps = 95/586 (16%)
Query: 21 KAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERD 80
K A PR +S +S + P PR P+ + + G S K P G++S E
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRS-----RSGSSSK---GRGPSPEGSSSTES- 1657
Query: 81 KTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSK 140
S H PP SR ++ +S+ + + +S + P +++ +SS
Sbjct: 1658 ------------SPEH------PPKSRTARRGSRSSPEPKTKSRT----PPRRRSSRSSP 1695
Query: 141 KHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQ-SRSRPRKSHRHRHHRCPSRSQSSESRP 199
+ R+ S++ R +SSSP+++ R RH++ S S P + + R SR + S S P
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS----SRRRRSASSP 1751
Query: 200 SSCESRHRGRSPE---EGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARG 256
+ + RGRSP G + R SRR + + SS+ S+ Q
Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQR-------- 1803
Query: 257 VITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGL 316
+++ S +T R Y S + S++TSS R RG+ + P+
Sbjct: 1804 ------------SRSRSRVTRRRRGGSGYHS-RSPARQESSRTSSRRRRGRSRTPPT--- 1847
Query: 317 SKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSL 376
S+ R + + + S + +SP SR R SR SP S
Sbjct: 1848 SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR-RRSRSRTSPV---------SR 1897
Query: 377 VPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYS 436
S +R+S + SRS + +R SRS P + R ++SR+ ++ +RS SR+P +
Sbjct: 1898 RRSRSRTSVTRRRSRSRASPVSR---RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVT 1954
Query: 437 SK-SGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS-YSPMR 494
+ S R+PP RSR S SR R + + S+ R RRR RS SP+
Sbjct: 1955 RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT 2014
Query: 495 KRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRS 554
+RR S + RR + +R +P R S S S A R SRSR+
Sbjct: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKR----------------SRSRSPLAIRRRSRSRT 2058
Query: 555 -RSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRS 599
R+ +RS TR+ + RS S S RSRS + +R+ S SR+
Sbjct: 2059 PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRT 2104
Score = 125 bits (315), Expect = 9e-29
Identities = 157/540 (29%), Positives = 227/540 (42%), Gaps = 80/540 (14%)
Query: 101 TPPPSSRGKKKKKKSTR-KKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSP 159
TP P SR + + + +R S S S V +K + +R RS S + S
Sbjct: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551
Query: 160 KSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRR 219
+ R E S+++ R R R S S+SR S SR G SPE K R
Sbjct: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS-GSSPEVKDKPRA 1610
Query: 220 RHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSR 279
+ SPE ++ P + P + + SGS+ S+
Sbjct: 1611 APRAQSGSD---SSPEPKAPAPRALPRR-----------SRSGSS-------------SK 1643
Query: 280 GRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSP 339
GR + + T S P S +R + SP +KSR +S S T +
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK-TKSRTPPRRRSSRSSPELTRKAR 1702
Query: 340 QNKGAMLENLSPTSRGRES-RGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAST 398
++ + + SP +R R R +SP + E + S RSS + RS+S T
Sbjct: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKS------RSSRRR---RSASSPRT 1753
Query: 399 RSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS 458
+++S RSP+P+ PR Q RS S +R +R+ +SG S S S R +RS S S
Sbjct: 1754 KTTSRRGRSPSPK--PRGLQ-RSRSRSRREKTRTTRRRDRSG--SSQSTSRRRQRSRSRS 1808
Query: 459 RYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIP 518
R + R Y + ++E R RRR R R R P+ +R+ + +R P P
Sbjct: 1809 RVTRRRRGGSGYHSRSPARQESSRTSSRRR-----RGRSRTPPT---SRKRSRSRTSPAP 1860
Query: 519 YYRP----SPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSR---------------SR 559
+ R SP++ S + S SRS + SR RSRSR SR
Sbjct: 1861 WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920
Query: 560 RRSRTRTSS----SSSSRSPSPGSRSRSR----SRSRSRSRSRSQSRSYSSADSYSSTRR 611
RRSR+RT S SR+P+ RSRSR +R RSRSR+ +R S + + TRR
Sbjct: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980
Score = 125 bits (313), Expect = 1e-28
Identities = 164/589 (27%), Positives = 241/589 (40%), Gaps = 59/589 (10%)
Query: 43 PRTEPQNNPVVPAQDGPSE-KLGQHLATEPLGTNSWERDKTCRELGAT-----RGHS-AS 95
P PQ++ + P K+ +H ++ P + RE+ ++ R H A
Sbjct: 409 PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
Query: 96 HDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRR--------RS 147
DK + PS R + + +T K+ R S S +P K+ +S RR RS
Sbjct: 469 RDKSHSHTPSRRMGRSRSPATAKRGR---SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS 525
Query: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHH-RCPSRSQSSESRPSSCESRH 206
S +RR S SP+ R+ Q R R R + R R H R P+ S SR + R
Sbjct: 526 RSPQRRGRSRSPQRPGWSRSRNT-QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRS 584
Query: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAAD 266
R R+P + R +RR S++ SR P++ R + S +
Sbjct: 585 RSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS 644
Query: 267 LFTKTASPLTTSRGRSQE-YDSGNDTSSPPSTQTSSARSR-----GQEKG-SPSGGLSKS 319
+++ +P R RS+ G S P+ ++ +RSR G+ + +P G S+S
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704
Query: 320 RELNSGNTSDSGNSFTTSSPQNKG-----AMLENLSPTSRGRESRGFQSPCLECAEVKKS 374
R L S S +PQ +G + +N S TS+ R SR SP E+KKS
Sbjct: 705 RSLVRRGRSHS------RTPQRRGRSGSSSERKNKSRTSQ-RRSRSNSSP-----EMKKS 752
Query: 375 SLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPS 434
+ +RS S + RS S SS P ++ +SRS SS+ ++ SR+P
Sbjct: 753 RISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPP 812
Query: 435 YSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE----RDPKYSEKDSQQRERERARRRRRS- 489
S+S PP + S++ S+S SP + P+ S Q + +RRS
Sbjct: 813 RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC 872
Query: 490 --YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR 547
SP + + +PS + R + R SPS S S S RS S
Sbjct: 873 FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
Query: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR-SRSRSRS 595
S S S SR SR R SRS SP S SR R S S S S
Sbjct: 933 SSSPSPSRVTSRTTPR-------RSRSVSPCSNVESRLLPRYSHSGSSS 974
Score = 100 bits (249), Expect = 4e-21
Identities = 159/629 (25%), Positives = 239/629 (37%), Gaps = 116/629 (18%)
Query: 77 WERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKK 136
W R + + G +R SA + + P++RG+ + + T +R RS S +P+ + + +
Sbjct: 542 WSRSRNTQRRGRSR--SARRGRSHSRSPATRGRSRSR--TPARRGRSRSRTPARRRSRSR 597
Query: 137 KSSKKHKRRRSFSKKRRHSSSSP---KSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
+++ R R+ +++ R S +P +S+ R R + +SRS R+S R R R P+R
Sbjct: 598 TPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS-RTPARRG 656
Query: 194 SSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLS 253
S SR + R R R+P ++S R SR ++ S + R S+ L G
Sbjct: 657 RSRSRTPARRGRSRSRTP--ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714
Query: 254 ARGVITG--SGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGS 311
+R SGS+++ K+ + SR S + SS S SS RS+ + +
Sbjct: 715 SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR-- 772
Query: 312 PSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEV 371
LS R L+ + S T G+ + R SR SP
Sbjct: 773 ----LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP-----PP 823
Query: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRA-SPRYTQSRSTSSEKRSYS 430
K+ S PS S + S R S +S N ++ +P+ +S + S
Sbjct: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS 883
Query: 431 RSPSYSSKSG------KRSPPSRSSRSRRS---PSYSRYSPSRERDPKYSEKDSQQRERE 481
R+PS S SG K S P R S SR S P R+R S S R
Sbjct: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTS 943
Query: 482 RAR-RRRRSYSP---MRKRRRDSPSHLEA-------------RRITSARKRPIPYYR--- 521
R RR RS SP + R SH + R+ S P P +
Sbjct: 944 RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT 1003
Query: 522 -PSPSSSGSLSST------------------------------SSWYSSSSSRSASRSYS 550
P PS SGS S S++ SS + +S +
Sbjct: 1004 PPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQT 1063
Query: 551 ----RSRSRSRSRRRSRTRTSSSSS----------SRSPSPGSRSRSRS----------- 585
RS + S R+S + + S S SRS SP + SRS
Sbjct: 1064 SPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123
Query: 586 -------RSRSRSRSRSQSRSYSSADSYS 607
S +SR +S S SY + DS S
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYPTVDSNS 1152
Score = 81.6 bits (200), Expect = 2e-15
Identities = 141/621 (22%), Positives = 231/621 (37%), Gaps = 99/621 (15%)
Query: 38 ARKPLPRTEPQNNPVV--PAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSAS 95
+R P R +PV P+ + G+ + P R +T G +R + +
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP-ARRGRSRSRTPARRGRSRSRTPA 675
Query: 96 H--DKDLTPPPSSRGKKKKKKSTRKKRR------RSSSYSPSPVKKKKKKSSKKHKRRRS 147
+ + P+ RG+ + + R + R R S+S +P ++ + SS + K +
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
Query: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHR---------HHRCPS-RSQSSES 197
S++R S+SSP+ K+ + +S S PR + R CP +SQ+
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
Query: 198 RPSSCESRHRGRSPEEGQKSRRRHS---RRCSKTLCKDS-------PEAQSSRPPSQPLQ 247
R S S+ + +S ++SR S ++ SKT + S P+ +S PP Q
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855
Query: 248 MLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGND-----TSSPPSTQTSSA 302
+ + V S F + P SR S+ SG+ +S+PP S +
Sbjct: 856 TSPQANEQSVTPQRRSC---FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRS 912
Query: 303 RS----------------RGQEKGSPSGGLSKSRELNSGNTSDSGNSFT----------T 336
S G SPS S++ S + S N + +
Sbjct: 913 SSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGS 972
Query: 337 SSPQNK--------GAMLENLSP-------TSRGRESRGFQSPCLECAEVKKSSLVPSTA 381
SSP K + ++SP T G G +SPC + E K SLV S
Sbjct: 973 SSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ--EKSKDSLVQSCP 1030
Query: 382 RSSPMKGCSRSS-----SYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYS 436
S + +SS SY S +S + SP + S+ ++S+S SPS
Sbjct: 1031 GSLSLCAGVKSSTPPGESYFGVSSLQLKGQS---QTSPDHRSDTSSPEVRQSHSESPSLQ 1087
Query: 437 SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSE----KDSQQRERERARRRRRSYSP 492
SKS RS S + SP R+ ++S K E+ R + SY
Sbjct: 1088 SKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPT 1147
Query: 493 MRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRS 552
+ DS S L R+ +A + P ++ S +S + S
Sbjct: 1148 V-----DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVF 1202
Query: 553 RSRSRSRRRSRTRTSSSSSSR 573
+ R+ R R+ SS ++
Sbjct: 1203 KDTLRTPPRERSGAGSSPETK 1223
Score = 74.3 bits (181), Expect = 3e-13
Identities = 93/339 (27%), Positives = 141/339 (41%), Gaps = 19/339 (5%)
Query: 189 PSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQM 248
PS+S+ + R S SR G++P + + R S S +++ + P+
Sbjct: 2414 PSQSRMTSERAPSPSSR-MGQAPSQSLLPPAQDQPR-SPVPSAFSDQSRCLIAQTTPVAG 2471
Query: 249 LGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQE 308
LS+ V T + SA D + P S + T + + ++ + +
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVP-APGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530
Query: 309 KGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLEC 368
+ S S S S +S ++S S +S +SS ++G+ L + R +P
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 369 AEVKKSSLVPSTA-RSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKR 427
E + P+ R S S SSS +S+ SSS SS S + +S + S S+SS
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 428 SYSRSPSYSSK--SGKRSPP-SRSSRSRRSPSYS-------RYSPSRER--DPKYSEKDS 475
P K S K+ PP R SRS R P S YSP R P+ S +D
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 476 QQRERERARRRRR---SYSPMRKRRRDSPSHLEARRITS 511
Q ER RR + S SP KRRR++PS R +S
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
Score = 73.6 bits (179), Expect = 5e-13
Identities = 106/391 (27%), Positives = 150/391 (38%), Gaps = 62/391 (15%)
Query: 205 RHRGRSPEEGQKSRRRHSRRC-SKTLCKDSPEAQSSRPPSQ-----PLQMLGYLSARGVI 258
R R R+P R S R S + +QS PP+Q P+ +R +I
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
Query: 259 ---TGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGG 315
T + L + + T+S G S P S S G ++ S
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 316 LSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSS 375
L ++E S ++S S +S ++SS + + + S +S S P + V +
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 376 LVPSTA-------RSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRS 428
P A +P K RSSS +S+ SSS SS S + +S + S S+SS S
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 429 YSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRR 488
S S +K G ++ P +S + P R R+ P S +DS R
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRK--PIDSLRDS----------RSL 2691
Query: 489 SYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRS 548
SYSP+ +RRR SP +PSP SSSS SR
Sbjct: 2692 SYSPV-ERRRPSP-------------------QPSPRDQ----------QSSSSERGSRR 2721
Query: 549 YSRSRSRSRSRRRSR----TRTSSSSSSRSP 575
R SRS S +R R R SSRSP
Sbjct: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 66.6 bits (161), Expect = 6e-11
Identities = 96/355 (27%), Positives = 138/355 (38%), Gaps = 44/355 (12%)
Query: 238 SSRPPSQPLQ--MLGYLSARGV----ITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDT 291
SSR P P ++G SA I GS +AA L +P + + R SG +
Sbjct: 2326 SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAAL-----APASLTSARMAPALSGANL 2380
Query: 292 SSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSP 351
+SP ++ R G+ S D S T S ++ M +P
Sbjct: 2381 TSPRVPLSAYERVSGR---------------TSPPLLDRARSRTPPSAPSQSRMTSERAP 2425
Query: 352 TSRGRESRGFQSPCLECAEVKKSSLVPST---------ARSSPMKGCSRSSSYASTRSSS 402
+ R + L A+ + S VPS A+++P+ G SS A ++S
Sbjct: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS 2485
Query: 403 HSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSP 462
+ + P S E + + + S+ + + R S S S S S S
Sbjct: 2486 SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545
Query: 463 SRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRP 522
S S S + E + + +++ +P+ EA R P P R
Sbjct: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR-EGRPPEPTPAKRK 2604
Query: 523 SPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSP 577
SSS S SS+SS SSSSS S+S S S S S S S SSSSSS SPSP
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--------SSSSSSSSPSP 2651
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/181 (33%), Positives = 84/181 (46%), Gaps = 34/181 (18%)
Query: 402 SHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYS 461
+ ++ P P Y+ R +SS SRSP+ K K+ + R RRS S S
Sbjct: 157 AREAKQPAPEPPKPYSLVRESSS-----SRSPTPKQKKKKK----KKDRGRRSESSS--- 204
Query: 462 PSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYR 521
P RER K S+K + E E +R+ RS +P KR+ +R T
Sbjct: 205 PRRERK-KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT----------- 252
Query: 522 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 581
P+P S + STS+ +SSS S RSRSRS ++T T ++ + RSPSP S
Sbjct: 253 PAPKSRRAHRSTSADSASSSDTS--------RSRSRS-AAAKTHT-TALAGRSPSPASGR 302
Query: 582 R 582
R
Sbjct: 303 R 303
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/202 (24%), Positives = 79/202 (39%), Gaps = 40/202 (19%)
Query: 407 SPNPRASPRYTQSRSTSSEKRSYSRSPSY----SSKSGKRSPPSRSSRSRRSPSYSR--- 459
+P R + T + +EK++ ++ S G P R +R + P+
Sbjct: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
Query: 460 YSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPY 519
YS RE S Q++++++ R RRS S +R R S + R S K+ +
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR-KH 229
Query: 520 YRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGS 579
P+P S + +S+ + R+RSR+ T P+P S
Sbjct: 230 RSPTPKS------------------------KRKSKDKKRKRSRSTT--------PAPKS 257
Query: 580 RSRSRSRSRSRSRSRSQSRSYS 601
R RS S + S SRS S
Sbjct: 258 RRAHRSTSADSASSSDTSRSRS 279
Score = 42.0 bits (97), Expect = 0.002
Identities = 122/564 (21%), Positives = 194/564 (34%), Gaps = 69/564 (12%)
Query: 95 SHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRH 154
SH ++P P K K T S S SP P ++K K S S S
Sbjct: 988 SHSGSISPYP------KVKAQTPPGPSLSGSKSPCP--QEKSKDSLVQSCPGSLSLCAGV 1039
Query: 155 SSSSPKSKRR---DEKRHKKQSRSRPRKSH-------RHRHHRCPSRSQSSESRPSSCES 204
SS+P + + K QS++ P R H PS S++ P S
Sbjct: 1040 KSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRS 1099
Query: 205 RHRGRSPEEGQKSRRRHSRR--CSKTLCKDSPEAQSSR----PPSQPLQMLGYLSARGVI 258
R E +S R R + + K + SR S P L + +
Sbjct: 1100 RSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRL 1159
Query: 259 TGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQT---SSARSRGQEKGSPSGG 315
+ S + T S R ++ S P + + R+ +E+ S +G
Sbjct: 1160 ETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRER-SGAGS 1218
Query: 316 LSKSRELNSGNTSDSGNS----FTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEV 371
+++E NS + S + S + G +L +LS + + F+S EV
Sbjct: 1219 SPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESS----PEV 1274
Query: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR 431
++ V T S + +S + S +S P SP + + ++ + S+
Sbjct: 1275 EERPAVSLTLDQSQSQ-----ASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG- 1328
Query: 432 SPSYSSKSGKRSPPSRSSRSR--RSPSYSRYSPSRERDPKYSEKDSQQR----------- 478
SP SG + S + + E DP K+ R
Sbjct: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSP 1388
Query: 479 ---ERERARRRRRSYSPMRKRRRDSPSHLEARRITSAR-KRPIPYYRPSPSSSGSL---- 530
E+ + SP+ +PS + +S K +P S SGS
Sbjct: 1389 DAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLR 1448
Query: 531 --SSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR 588
S T S +S S S + R+ SR RS S + ++P P SRS S
Sbjct: 1449 DGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP--QTPRPRSRSPSSPELN 1506
Query: 589 SR--SRSRSQSRSYSSADSYSSTR 610
++ + R +S S SS D + R
Sbjct: 1507 NKCLTPQRERSGSESSVDQKTVAR 1530
Score = 38.1 bits (87), Expect = 0.024
Identities = 58/244 (23%), Positives = 78/244 (31%), Gaps = 36/244 (14%)
Query: 99 DLTPPPSSRGKKKKKK----STRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRH 154
D+ PP+S G ++ K+RR SSS S S SS S
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 155 SSS-----------------SPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSES 197
SS +PK R+ + + R R+S S S SS S
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 198 RPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGV 257
SS S S S S S + K P+A +P S G +R
Sbjct: 2625 SSSSSSS-----SSSSSSSSSSSSSSSSSPSPAKPGPQA-LPKPASPKKPPPGERRSRSP 2678
Query: 258 ITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLS 317
S D + + SP+ R Q P Q SS+ RG +G S
Sbjct: 2679 RKPIDSLRDSRSLSYSPVERRRPSPQ---------PSPRDQQSSSSERGSRRGQRGDSRS 2729
Query: 318 KSRE 321
S +
Sbjct: 2730 PSHK 2733
Score = 37.0 bits (84), Expect = 0.053
Identities = 42/162 (25%), Positives = 55/162 (33%), Gaps = 14/162 (8%)
Query: 101 TPPPSS---RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSS 157
TP P G+ + ++KRR SSS S S SS S S SSS
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Query: 158 SPKSKRRDEKRHKKQSRSRPRKSHR----HRHHRCPSRSQSS--ESRPSSCESRHRGR-- 209
S S + Q+ +P + R R P + S +SR S R R
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702
Query: 210 ---SPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQM 248
SP + Q S R + SP + R P M
Sbjct: 2703 PQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPM 2744
Score = 35.4 bits (80), Expect = 0.15
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 102 PPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKS 161
PPP R + +K R S S S SPV++++ + ++S S +R S +
Sbjct: 2668 PPPGERRSRSPRKPI-DSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSER----GSRRG 2722
Query: 162 KRRDEKR--HKKQSRSRPRKSHRHRHHRCP 189
+R D + HK++ + + RHR R P
Sbjct: 2723 QRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 33.5 bits (75), Expect = 0.59
Identities = 46/218 (21%), Positives = 70/218 (32%), Gaps = 23/218 (10%)
Query: 87 GATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRR 146
G++ S + P + + + ++ R P+P K+K++ SS
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
Query: 147 SFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRH 206
S S SSSS S S S S + + S + P
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP---PGER 2673
Query: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAAD 266
R RSP + S R S++L E + P P S RG + G D
Sbjct: 2674 RSRSPR-----KPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERG--SRRGQRGD 2726
Query: 267 LFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARS 304
RS + +T SP + S+RS
Sbjct: 2727 -------------SRSPSHKRRRETPSPRPMRHRSSRS 2751
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 119 bits (298), Expect = 8e-27
Identities = 174/669 (26%), Positives = 264/669 (39%), Gaps = 95/669 (14%)
Query: 1 MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVA--SITARKPLPRTEP--QNNPVVPAQ 56
M+S ++ K G+ A P+P + + + S T + L T+P N V+
Sbjct: 1 MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPS 60
Query: 57 DGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKST 116
S K + S +R + R +R S + + K K
Sbjct: 61 SSKSTK-----------STSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDV 109
Query: 117 RKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRR------DEKRHK 170
R +RR + ++ +SSK+ R S + R + P R +K +
Sbjct: 110 RCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSR 169
Query: 171 KQSRSRPRKSHRHRHHRCPSRSQSSESRP------------------SSCESRHRGRSPE 212
+S RPR S+R R P RP + C++ S E
Sbjct: 170 GKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKE 229
Query: 213 EGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ-PLQMLGYLSARGVITGSGSAADLFTKT 271
+ SR+ P + S P++ ++ Y A + S +++
Sbjct: 230 KSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQA-----STRSRPQSHSQS 284
Query: 272 ASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQE-------KGSPSGGLSKSRELNS 324
SP SR SQ+ S S ARSR ++ + S S SK + N
Sbjct: 285 RSP-RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQ 343
Query: 325 GNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSS 384
T G S S +K + +S+ R+ RG SP E + S P+ R
Sbjct: 344 SRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS--PNKQRDH 401
Query: 385 PMKGCSRSSSYASTRSSSHS-------SRSPNPRASPRYTQSRST-SSEKRSYSRSPSYS 436
SRS + A RS S S SRS +P + ++SRS + RS SRSP+ +
Sbjct: 402 SR---SRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA 458
Query: 437 -SKSGKRSPPSRSSRSR-RSPSYSRY-----SPSRERDPKYSEKDSQQRERERARR---- 485
S RSP RSR RSPS R SPS+ERD + S S++R+ ++R
Sbjct: 459 RDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
Query: 486 --RRRSYSPMRKR-RRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSS 542
RRS SP ++R RR S S + R + +R SPS S S S
Sbjct: 519 RDHRRSRSPSKERQRRQSRSPNKERDRSQSR---------SPS-----EEREHRQSRSPS 564
Query: 543 RSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS-RSRSRSRSRSRSRSQSRSYS 601
+ R RS S+ R RR+SR+ + SRS SP +S SR R+ S+ ++ S+SR+ S
Sbjct: 565 KERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624
Query: 602 SADSYSSTR 610
++S +R
Sbjct: 625 KEGNHSQSR 633
Score = 119 bits (298), Expect = 8e-27
Identities = 149/536 (27%), Positives = 216/536 (40%), Gaps = 72/536 (13%)
Query: 95 SHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRH 154
S +K P PSS +K K R SYSP+ + + K ++ R S+ + H
Sbjct: 227 SKEKSDNPSPSS-SRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR----SRPQSH 281
Query: 155 SSSSPKSKRRDEKRHKKQSRSRPRK-SHRHRHHRCPSRSQ----SSESRPSSCESRHRGR 209
S S +S RR +K++ SR R S + H R SR++ S R S S +G+
Sbjct: 282 SQS--RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGK 339
Query: 210 SPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269
S + + RR S S+ K+ + S
Sbjct: 340 SQNQSRTPRRGRSHNWSRNPSKERSHSHS------------------------------- 368
Query: 270 KTASPLTTSRGRSQ-EYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTS 328
+++S RG S +SG S P+ Q +RSR SP+ +SR +
Sbjct: 369 RSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSR-----SPNKARDRSRSRSPYKAR 423
Query: 329 DSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARS----- 383
D S SP + SP SR +SP A S P+ AR
Sbjct: 424 DRSRS---RSPNKARDCSRSRSPYKARDRSRS-RSP--NKARDHSRSRSPNKARDRSRSR 477
Query: 384 SPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK-RSYSRSPSYS-SKSGK 441
SP K S + ++ H RS +P + QSRS+S E+ SRSPS +
Sbjct: 478 SPSKERDHSQLGSPSKERDHR-RSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 442 RSPPSRSSRSR-RSPSYSRY-----SPSRERDPKYSEKDSQQRERERARRRRRSYSPMRK 495
RSP RS+ RSPS R SPS+ERD + S++RER ++R R
Sbjct: 537 RSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRS 596
Query: 496 RRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSR 555
R + S R +S K PS + S S TSS S S + RS RS
Sbjct: 597 RSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSP 656
Query: 556 SRSRRRSRTRTSSSSSSRSPS---PGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608
+R+ S+ RT S +SS SPS G ++ S+ S++ + + + + S SS
Sbjct: 657 TRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 76.3 bits (186), Expect = 8e-14
Identities = 93/319 (29%), Positives = 142/319 (44%), Gaps = 40/319 (12%)
Query: 324 SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARS 383
S + + SG+S T+ P+ ++ S T S P A + S + PS+++S
Sbjct: 11 SMSLAPSGSSMPTADPKPPASLKSTKSATPN--RSLVPTKP----ATSRNSVMSPSSSKS 64
Query: 384 SPMKGCSRS-SSYASTRSSSHS-SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYS----- 436
+ R+ S+ S+RS S +R+P+ ++ T S +S+ R + R ++S
Sbjct: 65 TKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTP 124
Query: 437 ----SKSGKRSPPSRSSRSR-RSPSYSRYSPSRERDPKYSEKDSQQRE--RERARRRRRS 489
S+S KRSP S+ R R+ SR R P +K S+ + R R R RS
Sbjct: 125 GRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERS 184
Query: 490 YSPMRKRRRDS-----------PSHLEARRITSARKRP--IPYYR----PSPSSSGSLSS 532
S R + S S L T+ + P IP PSPSSS + S
Sbjct: 185 DSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKS 244
Query: 533 TSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSR 592
S +S S + SR +S ++ +R+R S S SRSP RSRS S+ R+ SR
Sbjct: 245 YGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPR---RSRSGSQKRTHSR 301
Query: 593 SRSQSRSYSSADSYSSTRR 611
RS S + + + S TR+
Sbjct: 302 VRSHSWKRNHSRARSRTRK 320
Score = 32.7 bits (73), Expect = 1.0
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 9/99 (9%)
Query: 522 PSPSSSGSLS---STSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTS-----SSSSSR 573
P SS S+S S SS ++ AS ++S + +RS ++ TS S SSS+
Sbjct: 4 PKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSK 63
Query: 574 SPSPGSRSRSRS-RSRSRSRSRSQSRSYSSADSYSSTRR 611
S S R+ S R SRSR RS++R+ S + + T +
Sbjct: 64 STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSK 102
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 117 bits (292), Expect = 4e-26
Identities = 138/511 (27%), Positives = 201/511 (39%), Gaps = 69/511 (13%)
Query: 102 PPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKS 161
P P KK+K+K + R RS S S S + + ++ +R RS S+ S SP+
Sbjct: 259 PSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR-----SYSPRR 313
Query: 162 KRRDEKRHKKQSRSRPRKSH---RHRHHRCP----SRSQSSESRPSSCESRHRGRSPEEG 214
+ +R + R+ PR+ RHR R P RS +S S SS S R RSP +
Sbjct: 314 RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK 373
Query: 215 QKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASP 274
R R ++ L + + PS P + + +P
Sbjct: 374 PPKRTSSPPRKTRRLSPSASPPRRRHRPSPP----------------ATPPPKTRHSPTP 417
Query: 275 LTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSF 334
++R R + SP T + +G EK K R++
Sbjct: 418 QQSNRTRKSRV-----SVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE----------- 461
Query: 335 TTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKG-CSRSS 393
+ S ++KG + + R+ R + SS RS G R
Sbjct: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521
Query: 394 SYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKR----SPPSRSS 449
++ +RS+S S R SPR + RS S RSPS + +R PP R +
Sbjct: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581
Query: 450 RS----RRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLE 505
S RRSPS RYSP +R +YS +RR + P +RR SPS
Sbjct: 582 PSPPPRRRSPSPRRYSPPIQR--RYSPSPPP--------KRRTASPPPPPKRRASPSPPP 631
Query: 506 ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRT- 564
RR++ + P P R SP + S SS + S S SRS +RS ++R S +
Sbjct: 632 KRRVSHS---PPPKQRSSPVTKRRSPSLSSKHRKGS--SPSRSTREARSPQPNKRHSPSP 686
Query: 565 RTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595
R + +S SP P R S S R +S S S
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPS 717
Score = 86.7 bits (213), Expect = 6e-17
Identities = 137/618 (22%), Positives = 224/618 (36%), Gaps = 76/618 (12%)
Query: 42 LPRTEPQNNPVVPAQDGPSEKLGQHLATEPLG-TNSWERDKT-CRELGATRGHSASHDKD 99
+P+ EP P P+ + S+K + T P + S R +T R TR +
Sbjct: 247 VPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRS 306
Query: 100 LTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSP 159
+ P R +++ S R RR P P + ++ +S + +RR S S SSSS
Sbjct: 307 RSYSPRRRPSPRRRPSPR--RRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS 364
Query: 160 KSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRR 219
R K+ K++ S PRK+ R P R + S P++ + R SP Q +R
Sbjct: 365 SRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR-HSPTPQQSNRT 423
Query: 220 RHSR----------RCSKTLCKDSPEAQSSRPPSQPLQML-------GYLSARGVIT--- 259
R SR + +K + E+ S P + +++ G ++A +
Sbjct: 424 RKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRR 483
Query: 260 --------------GSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSR 305
S S+ D K + GR + + S P + R
Sbjct: 484 QYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR 543
Query: 306 GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNK--GAMLENLSPTSRGRESRGFQ- 362
G+ + SPS ++ R S T P+ + SP+ R R S Q
Sbjct: 544 GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR-RYSPPIQR 602
Query: 363 --SPCLECAEVKKSSLVPSTARSSPMKGCSR-----------SSSYASTRSSSHSSRSPN 409
SP S P R+SP R SS RS S SS+
Sbjct: 603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK 662
Query: 410 PRASPRYT-QSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDP 468
+ R T ++RS KR +S SP + SPP + SP R SPS P
Sbjct: 663 GSSPSRSTREARSPQPNKR-HSPSPRPRAPQTSSSPPPVRRGASSSPQ-RRQSPSPSTRP 720
Query: 469 KYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARK---RPIPYYRPSPS 525
RR R+ P + ++ SPS RR++S+R P P + P+
Sbjct: 721 --------------IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766
Query: 526 SSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRS 585
+ S S + S + ++ S + S S R + + + +
Sbjct: 767 PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHK 826
Query: 586 RSRSRSRSRSQSRSYSSA 603
+ + + ++ + + ++A
Sbjct: 827 KHKKHKKEKAVAAAAAAA 844
Score = 79.7 bits (195), Expect = 7e-15
Identities = 140/567 (24%), Positives = 198/567 (34%), Gaps = 88/567 (15%)
Query: 128 PSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187
PS + KK+ K+ + + + + ++EK ++ R R R S R R R
Sbjct: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSR-SPRRRKSR 178
Query: 188 CPS-RSQSS-----ESRPSSCESRHRGRS----------------PEEGQKSRRRHSRRC 225
PS R +SS R S RHR +S PE K + +
Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEA 238
Query: 226 SKT-----LCKDSPEAQSSRP-PSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTT-- 277
+ T + K P + P P + + + S S + T++ SP T
Sbjct: 239 TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRP 298
Query: 278 ---SRGRSQEYDSGNDTS---------------SPPSTQTSSARSRGQEKGSPSGGLSKS 319
R RS+ Y S PP + +RS + + S LS S
Sbjct: 299 RRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358
Query: 320 RELNSGNTSDSGNS---FTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSL 376
+S + S S TSSP K LSP++ R SP + S
Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRK---TRRLSPSASPPRRRHRPSPPATPPPKTRHSP 415
Query: 377 VPS----TARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK------ 426
P T +S R+S + + SP+P PR + + +K
Sbjct: 416 TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAA 475
Query: 427 -------RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS-------RYSPSRERDPKYSE 472
R Y R SS S S R +RS + R+SPSR P +
Sbjct: 476 ADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK 535
Query: 473 KDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSA----RKRPI-PYYRPSPSSS 527
+ + R R RRR S P R+RR SP+ RR T R+ P P R SPS
Sbjct: 536 RQKETSPRGR-RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR 594
Query: 528 GSLSSTSSWYSSS---SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSR 584
YS S R+AS R S S R + S + SP ++ RS
Sbjct: 595 RYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 654
Query: 585 SRSRSRSRSRSQSRSYSSADSYSSTRR 611
S S + S SRS A S +R
Sbjct: 655 SLSSKHRKGSSPSRSTREARSPQPNKR 681
Score = 70.9 bits (172), Expect = 3e-12
Identities = 114/527 (21%), Positives = 198/527 (37%), Gaps = 82/527 (15%)
Query: 41 PLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDL 100
P P +P+ V + +K G+ A + + R + + + S+S D+
Sbjct: 451 PSPAPKPRK---VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER- 506
Query: 101 TPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFS----KKRRHSS 156
P K + R++ S S SPSP +K++K++S + +RRRS S ++RR S
Sbjct: 507 ---PKRSHVKNGEVGRRRRHSPSRSASPSP-RKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
Query: 157 SSPKSKRR----DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPE 212
+P +RR R + S R+S R + P + + S S P + R SP
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP----PKRRTASPP 618
Query: 213 EGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTA 272
K R S + + P Q S P TK
Sbjct: 619 PPPKRRASPSPPPKRRVSHSPPPKQRSSP--------------------------VTKRR 652
Query: 273 SPLTTSRGRSQEYDSGNDTSSPPSTQTSSARS-RGQEKGSPSGGLSKSRELNSGNTSDSG 331
SP +S+ R S PS T ARS + ++ SPS + R + ++
Sbjct: 653 SPSLSSKHRK---------GSSPSRSTREARSPQPNKRHSPS---PRPRAPQTSSSPPPV 700
Query: 332 NSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSR 391
+SSPQ + ++ SP++R P + + + A SP
Sbjct: 701 RRGASSSPQRR----QSPSPSTR---------PIRRVSRTPEPKKIKKAASPSPQSVRRV 747
Query: 392 SSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRS 451
SSS + + S +++ P SP +QS ST + SP+ K K SP S
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPST-------NWSPAVPVKKAK-SPTPSPSPP 799
Query: 452 RRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITS 511
R S +++ K +KD + ++ ++ ++ + + +P+ + A T
Sbjct: 800 RNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAA--AAAAAVTPAAIAAATTTL 857
Query: 512 ARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRS 558
A++ P+ P + A RS +++ +S
Sbjct: 858 AQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS 904
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 105 bits (263), Expect = 9e-23
Identities = 155/585 (26%), Positives = 215/585 (36%), Gaps = 94/585 (16%)
Query: 109 KKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKR 168
+KK+KK T + SSS S S + +S +H+R R KRR PK KR ++R
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSS-SESSSESELEHERSRRRKHKRR-----PKVKRSKKRR 239
Query: 169 HKKQSRSRPRKSHRHRHHRCPSRSQSSESRP--SSCESRHRGRSPEEGQKSRRRHSRRCS 226
+ S PR H RS ++E R SS + PEE
Sbjct: 240 KEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRF---- 295
Query: 227 KTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRS-QEY 285
L +D P + P P + ++ SG T T R RS E
Sbjct: 296 -LLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIK-GRGTIRYHTPPRSRSCSES 353
Query: 286 DSGNDTSSPPSTQTSSAR------------SRGQEKGSPSGGLSKSRELNSGNTSDSGNS 333
D + + +PP + R S+G + P R L+ + S S N
Sbjct: 354 DDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNG 413
Query: 334 FTT--SSPQNKGAMLENLSPTSRGRESRGF-QSPCLECAEVKKSS-LVPSTARSSPMK-- 387
+ + S+ ++ G + + +G Q C + KK L+PS SS
Sbjct: 414 YYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTR 473
Query: 388 ----GCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSY---SRSPSYSSKSG 440
C R S S+ SSH S + S + QS T S + SY S S SYS S
Sbjct: 474 RMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSS 533
Query: 441 KRSPPSRSSRSRRSPSYSRYSPS---RERDPKYSEKDSQQRERERARRRR---------- 487
+ S+SS RS S SR S R+R K K + Q + +
Sbjct: 534 RSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNE 593
Query: 488 -----------------------RSYSPMRKRRRDSPSHLEARRITSARKRPIPY----- 519
+ P +K + S ++ + + PI
Sbjct: 594 NVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLA 653
Query: 520 ----------YRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRS---RSRSRSRRRSRTRT 566
Y +S S ST S YS SS S+ RS SRS RS SRS RSR+
Sbjct: 654 NIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLA 713
Query: 567 SSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
SS S SRSPS S SR++ S+ S S SS D + RR
Sbjct: 714 SSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRR 758
Score = 94.0 bits (232), Expect = 4e-19
Identities = 150/599 (25%), Positives = 210/599 (35%), Gaps = 118/599 (19%)
Query: 92 HSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKK 151
HS D SS + + + RRR HKRR
Sbjct: 194 HSEGSDSSSNSSSSSESSSESELEHERSRRRK------------------HKRR------ 229
Query: 152 RRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR--PSSCESRHRGR 209
PK KR ++R + S PR H RS ++E R SS +
Sbjct: 230 -------PKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVV 282
Query: 210 SPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269
PEE L +D P + P P + +S +
Sbjct: 283 RPEEIPPVPENRF-----LLRRDMPVVTAEPEPKIP-DVAPIVSDQKPSVSKSGRKIKGR 336
Query: 270 KTASPLTTSRGRS-QEYDSGNDTSSPPSTQTSSAR------------SRGQEKGSPSGGL 316
T T R RS E D + + +PP + R S+G + P
Sbjct: 337 GTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSR 396
Query: 317 SKSRELNSGNTSDSGNSFTT--SSPQNKGAMLENLSPTSRGRESRG-FQSPCLECAEVKK 373
R L+ + S S N + + S+ ++ G + + +G Q C + KK
Sbjct: 397 WDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKK 456
Query: 374 SS-LVPSTARSSP------MKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK 426
L+PS SS C R S S+ SSH S + S + QS T S +
Sbjct: 457 RRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSR 516
Query: 427 RSY---SRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPS---RERDPKYSEKDSQQRER 480
SY S S SYS S + S+SS RS S SR S R+R K K + Q
Sbjct: 517 DSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSE 576
Query: 481 ERARRRR---------------------------------RSYSPMRKRRRDSPSHLEAR 507
+ + + P +K + S ++
Sbjct: 577 NKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEM 636
Query: 508 RITSARKRPI---------------PYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR- 551
+ + PI Y +S S ST S YS SS S+ RS SR
Sbjct: 637 KAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRS 696
Query: 552 SRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
SRSRS SR +R+R+ +SS SRS SP SRS SR++ S+ S+S SY+S S R
Sbjct: 697 SRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQC-SRSSSYTSISSDDGRR 754
Score = 87.8 bits (216), Expect = 3e-17
Identities = 146/580 (25%), Positives = 219/580 (37%), Gaps = 117/580 (20%)
Query: 91 GHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSK 150
G S L+ P SSR ++ + +R RS SY+ + S HK+RR K
Sbjct: 380 GEKWSKGDKLSDPCSSRWDER----SLSQRSRSWSYNGYYSDLSTARHSGHHKKRRK-EK 434
Query: 151 KRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRP----SSCESRH 206
K +H +K+ KKQ R K + R PS +SS+S SSC+
Sbjct: 435 KVKH-----------KKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCD--- 480
Query: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAAD 266
R RS S S+R K + QSS
Sbjct: 481 RERSSRSSSLSSHHSSKR---DWSKSDKDVQSS--------------------------- 510
Query: 267 LFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGN 326
T ++ S+ SQ Y G+ S S +S +RSR + + S G K +
Sbjct: 511 -LTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRK 569
Query: 327 TSD--SGNSFTTSSP------QNKGAML-----ENLS--------PTSRGRESRGFQSPC 365
T+ S N + P QN+ ++ EN+ P SR + + P
Sbjct: 570 TASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPS 629
Query: 366 LECAE---VKKSSLVP--STARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQS- 419
E + K + L+P ST + +K SSSY +S S +S + S R ++S
Sbjct: 630 YERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESS 689
Query: 420 ---RSTSSEKRSYSRSPSYS-----SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYS 471
RS SS RSYSRS + S S S RSP SRS + +S+ S S S
Sbjct: 690 PRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISS 749
Query: 472 EKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSA-RKRPIPYYRPSPSS---- 526
+ + + R R+ ++ S S +K S L ++ + R + Y S SS
Sbjct: 750 DDGRRAKRRLRSSGKKNSVSH-KKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYS 808
Query: 527 ----SGSLSSTSSWYSSSSSRSASRSYS-----RSRSRSRSRRR---SRTRT-------- 566
S+ +T S R+++ R +S+S R S+ RT
Sbjct: 809 SDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDH 868
Query: 567 --SSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSAD 604
+ S R GS+ S S S S++ S+ S+D
Sbjct: 869 LRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSD 908
Score = 82.0 bits (201), Expect = 1e-15
Identities = 133/571 (23%), Positives = 220/571 (38%), Gaps = 123/571 (21%)
Query: 74 TNSWERDKTCRELGATR--GHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPV 131
+ SW + +L R GH K+ +GKK+K K+ ++ PS +
Sbjct: 406 SRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDI 465
Query: 132 KKKKKKS------------------SKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQS 173
+ K + S H +R +SK + SS RD R K S
Sbjct: 466 ESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHS 525
Query: 174 RSRPRKSHRHR-------HHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCS 226
+S R S R R H R S+S+SS S+ H +R S
Sbjct: 526 QSYSRGSSRSRTASKSSSHSRSRSKSRSS---------------------SKSGHRKRAS 564
Query: 227 KTLCKDSPEAQSSRP-PSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEY 285
K+ K + + ++P ++PL+ V+ A ++ PL
Sbjct: 565 KSPRKTASQLSENKPVKTEPLRAT-MAQNENVVVQPVVAENI---PVIPL---------- 610
Query: 286 DSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM 345
+ SPP ++ GQ+ PS + + + + ++++ ++ + G+
Sbjct: 611 -----SDSPPPSRWKP----GQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGS- 660
Query: 346 LENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHS- 404
+ S R + S QS + ++ S S +RSS + SRS + + + +SSHS
Sbjct: 661 --SSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSR 718
Query: 405 SRSPNPRASPRYTQSRSTSSEKRSYSRSPSY---SSKSGKRSPPS-RSSRSRRSPSYSRY 460
SRSP+ R + SR+ S+ SRS SY SS G+R+ RSS + S S+ ++
Sbjct: 719 SRSPSSR-----SHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKH 773
Query: 461 SPSRERD---------------PKYSE--------KDSQQ---------RERERARRRRR 488
S S E+ KYSE DS+Q +E+E+ + R
Sbjct: 774 SSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMER 833
Query: 489 SYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLS-----STSSWYSSSSSR 543
+++ K R + S E R ++KR + +GS + S W S S+S
Sbjct: 834 THNKQEKNRGEEKSKSE-RECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSE 892
Query: 544 SASRSYSRSRSRSRSRRRSRTRTSSSSSSRS 574
S++ S S + TS S S S
Sbjct: 893 RDVTKNSKNDSHPSSDKEEGEATSDSESEVS 923
Score = 75.9 bits (185), Expect = 1e-13
Identities = 103/412 (25%), Positives = 158/412 (38%), Gaps = 67/412 (16%)
Query: 258 ITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQE-KGSPSGGL 316
+ + S D+F K T S G +S + + S ++ RSR ++ K P
Sbjct: 175 VLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKR 234
Query: 317 SKSRELNSGNTSDSGN-------------------SFTTSSPQNKGAML-ENLSPTSRGR 356
SK R + ++ + N S +S+ + K + E + P R
Sbjct: 235 SKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENR 294
Query: 357 ESRGFQSPCLECAEVKK--------SSLVPSTARSSPM---KGCSRSSSYASTRSSSHSS 405
P + K S PS ++S +G R + +RS S S
Sbjct: 295 FLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESD 354
Query: 406 RSPNPRASPRYTQS-------RSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS 458
+ P + + R S EK +S+ S R S+ RS SY+
Sbjct: 355 DDDSSETPPHWKEEMQRLRAYRPPSGEK--WSKGDKLSDPCSSRWDERSLSQRSRSWSYN 412
Query: 459 RY-------SPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITS 511
Y S + EK + +++ + ++ R + +KRR PS +E+ + +S
Sbjct: 413 GYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSK-SS 471
Query: 512 ARKRPIPYYRPSPSSSGSLSSTSS----WYSSS---------SSRSASRSYSRSRSRSRS 558
R+ R S S SLSS S W S SSR + RS S S+S SR
Sbjct: 472 TRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRG 531
Query: 559 RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
RSRT + SSS SR SRS+SRS S+S R R+ +A S +
Sbjct: 532 SSRSRTASKSSSHSR-----SRSKSRSSSKSGHRKRASKSPRKTASQLSENK 578
Score = 71.2 bits (173), Expect = 3e-12
Identities = 128/566 (22%), Positives = 216/566 (38%), Gaps = 61/566 (10%)
Query: 57 DGPSEKLGQHLATEPLGTNSWER----DKTCRELGATRGHSASHDKDLTPPPSSRGKKKK 112
D SE H+ +P +S D + R ++ + + ++RGK +K
Sbjct: 917 DSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQK 976
Query: 113 KKSTRKK--RRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHK 170
K K+ +R + +K KK K K KR+++F + + + D+K+
Sbjct: 977 HKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVT 1036
Query: 171 KQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLC 230
++S+ +K + + ++ +S +H + + + S
Sbjct: 1037 QESKE--KKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLS---- 1090
Query: 231 KDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSA--ADLFTKTASPLTTSRGRSQEYDS- 287
SP A ++ LQ + ++ V G D + +P +S + +E
Sbjct: 1091 -ISPTALNTEENVACLQNIQHVE-ESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPL 1148
Query: 288 GNDTSSPPS-----TQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNK 342
GN P Q + E +S+S+ L DS ++ S+ ++
Sbjct: 1149 GNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGEST 1208
Query: 343 GAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSS 402
G E AE + +L+ + P++G ++ + SS+
Sbjct: 1209 GKK---------------------EVAEKSQINLIDK--KWKPLQGVGNLAAPNAATSSA 1245
Query: 403 HSSR--SPNPRASPRYTQSRSTSSEK---RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSY 457
+ + P P+ + S K S +++ +R SS ++P
Sbjct: 1246 VEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTP-- 1303
Query: 458 SRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPI 517
SR S+ R P S S+ + R R R SYS R R R S S +R + +R R
Sbjct: 1304 SRDDDSQSRSPSRSRSKSETKSRHRT--RSVSYSHSRSRSRSSTSSYRSRSYSRSRSR-- 1359
Query: 518 PYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRS-RSRRRSRTRTSSSSSSRSPS 576
+Y S + S +SS+ S S R++SRS SRS S SR RS T S S SRS S
Sbjct: 1360 GWY----SRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRS 1415
Query: 577 PGSRSRSRSRSRSRSRSRSQSRSYSS 602
RS S R RS +R RSY S
Sbjct: 1416 RSQRSDSYHRGRSYNRRSRSCRSYGS 1441
Score = 67.0 bits (162), Expect = 5e-11
Identities = 132/555 (23%), Positives = 208/555 (37%), Gaps = 87/555 (15%)
Query: 118 KKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRP 177
K +SS+ + P KSSK+ R+ + S S+ ++ R ++HK S+
Sbjct: 930 KPTTKSSTNTSLPDDNGAWKSSKQ----RTSTSDSEGSCSNSENNRGKPQKHKHGSKENL 985
Query: 178 RKSH-----------RHRHHRCPSRSQSSESRPS---SCESRHRGRSPEEGQKSRRRHSR 223
++ H + + H+ P R Q+ +P E + Q+S+ +
Sbjct: 986 KREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVS 1045
Query: 224 RCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQ 283
++T+ + + + S LS + S D FTK S L+ S
Sbjct: 1046 ENNETIKDNILKTEKSSEED--------LSGKHDTVTVSSDLDQFTKDDSKLSISPTALN 1097
Query: 284 EYDSGN--------DTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS-- 333
++ + S P + E +P +S TS GN+
Sbjct: 1098 TEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPD----RSSPAKVEETSPLGNARL 1153
Query: 334 ------------FTTSSPQNKGAMLENLSPTSR-----GRE--------SRGFQSPCLEC 368
T PQ + E+ S+ G++ S G + E
Sbjct: 1154 DTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEV 1213
Query: 369 AEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSR--SPNPRASPRYTQSRSTSSEK 426
AE + +L+ + P++G ++ + SS+ + + P P+ + S K
Sbjct: 1214 AEKSQINLIDK--KWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNK 1271
Query: 427 ---RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERA 483
S +++ +R SS ++PS R S+ R P S S+ + R R
Sbjct: 1272 VRPGSLFDEVRKTARLNRRPRNQESSSDEQTPS--RDDDSQSRSPSRSRSKSETKSRHRT 1329
Query: 484 RRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSR 543
R SYS R R R S S +R + +R R + S S S S S +SS SR
Sbjct: 1330 RSV--SYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSR 1387
Query: 544 SASRSYS-RSRSRSR------SRRRSRTRTSSSSS---SRSPSPGSRS-RSRSRSRSRSR 592
S S SY SRSRS SR RSR+R+ S S RS + SRS RS R
Sbjct: 1388 SRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDR 1447
Query: 593 SRSQSRSYSSADSYS 607
S S RS S + YS
Sbjct: 1448 SYSHHRSPSESSRYS 1462
Score = 64.7 bits (156), Expect = 2e-10
Identities = 47/93 (50%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Query: 521 RPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSR 580
RP S S T S S SRS SRS S+S ++SR R RS + + S S SRS + R
Sbjct: 1290 RPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYR 1349
Query: 581 SRSRSRSRSR---SRSRSQSRSYSSADSYSSTR 610
SRS SRSRSR SR R++SRS SS SY S R
Sbjct: 1350 SRSYSRSRSRGWYSRGRTRSRS-SSYRSYKSHR 1381
Score = 60.5 bits (145), Expect = 4e-09
Identities = 46/110 (41%), Positives = 59/110 (53%), Gaps = 7/110 (6%)
Query: 505 EARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRT 564
E R+ +RP S + S S S S SRS S + SR R+RS S SR+
Sbjct: 1280 EVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRS 1339
Query: 565 RTSSSSSSRSPSPGSRSRSRSRSR---SRSRSRSQSRSYSSADSYSSTRR 611
R+ SS+SS SRS SRSRSR SR R+RS+S SY S S+ ++ R
Sbjct: 1340 RSRSSTSSYR----SRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSR 1385
Score = 59.3 bits (142), Expect = 1e-08
Identities = 101/474 (21%), Positives = 171/474 (36%), Gaps = 79/474 (16%)
Query: 29 ESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERD-KTCRELG 87
E+++V + A +N PV+P D P + G W+ + +E+
Sbjct: 593 ENVVVQPVVA---------ENIPVIPLSDSPPPSRWKP------GQKPWKPSYERIQEMK 637
Query: 88 ATRGHSASHDKDLTPPPSSRG----KKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
A H L P S+ K+ S+ KR ++S S K +SS+
Sbjct: 638 AKTTH-------LLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSP 690
Query: 144 RRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCE 203
R RS S + R S S R H SRSR S H ++ SQ S S
Sbjct: 691 RSRSRSSRSRSYSRSYTRSRSLASSH---SRSRSPSSRSHSRNKYSDHSQCSRS------ 741
Query: 204 SRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGS 263
S + S ++G++++RR K + SS + G S
Sbjct: 742 SSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKG--------RDRSS 793
Query: 264 AADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELN 323
++++ S L +Y S ++ SS +TQ++ + + G + ++
Sbjct: 794 CVRKYSESRSSL--------DYSSDSEQSSVQATQSAQEKEK-------QGQMERTHNKQ 838
Query: 324 SGNTSDSGNSFTTSSPQNKGAML-ENLS--------PTSRGRESRGFQSPCLECAEVKKS 374
N + + P +K L ENLS P + + S +V K+
Sbjct: 839 EKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKN 898
Query: 375 SLVPSTARSSPMKGCSRSSSYA-----------STRSSSHSSRSPNPRASPRYTQSRSTS 423
S S S +G + S S + +T+SS+++S + A Q STS
Sbjct: 899 SKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTS 958
Query: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ 477
+ S S S + K K S+ + R + ++D K+ +Q
Sbjct: 959 DSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQ 1012
Score = 57.4 bits (137), Expect = 4e-08
Identities = 49/101 (48%), Positives = 56/101 (55%), Gaps = 14/101 (13%)
Query: 523 SPSSSGSLSSTSSWY---------SSSSSRSASRSYSRSRSRSRSRRR---SRTRTSSSS 570
SPS S S S T S + S S SRS++ SY RSRS SRSR R SR RT S S
Sbjct: 1313 SPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSY-RSRSYSRSRSRGWYSRGRTRSRS 1371
Query: 571 SSRSPSPGSRSRSRSRSRSRSRS-RSQSRSYSSADSYSSTR 610
SS R+ SRSRSRS S S+SRSY+ YS +R
Sbjct: 1372 SSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSR 1412
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/161 (33%), Positives = 73/161 (45%), Gaps = 18/161 (11%)
Query: 95 SHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKR-- 152
S D D SR + K + +R R RS SYS S + + +SS R RS+S+ R
Sbjct: 1304 SRDDDSQSRSPSRSRSKSETKSRH-RTRSVSYSHS---RSRSRSSTSSYRSRSYSRSRSR 1359
Query: 153 ----RHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRG 208
R + S S R K H+ SRSR R S H R SRS + +S S SR R
Sbjct: 1360 GWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSR--SRSYTYDSYYSRSRSRSRS 1417
Query: 209 RSPEEGQKSR--RRHSRRCSKTLCKDSPEAQS---SRPPSQ 244
+ + + R R SR C ++ DS +S R PS+
Sbjct: 1418 QRSDSYHRGRSYNRRSRSC-RSYGSDSESDRSYSHHRSPSE 1457
Score = 45.1 bits (105), Expect = 2e-04
Identities = 67/251 (26%), Positives = 98/251 (39%), Gaps = 52/251 (20%)
Query: 93 SASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKR 152
SA K LT P + K + R + + + P + + +K+++ ++R R+ +
Sbjct: 1244 SAVEVKVLTTVP-----EMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRN----Q 1294
Query: 153 RHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHH-RCPSRSQS---SESRPSSCESRHRG 208
SS R D+ + + SRSR + + RH R S S S S S SS SR
Sbjct: 1295 ESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYS 1354
Query: 209 RSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLF 268
RS G SR R R S Y S + T S S
Sbjct: 1355 RSRSRGWYSRGRTRSRSS-----------------------SYRSYKSHRTSSRSR---- 1387
Query: 269 TKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNS---- 324
++++S SR RS YDS S +RSR Q S G S +R S
Sbjct: 1388 SRSSSYDPHSRSRSYTYDS--------YYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSY 1439
Query: 325 GNTSDSGNSFT 335
G+ S+S S++
Sbjct: 1440 GSDSESDRSYS 1450
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/174 (24%), Positives = 68/174 (39%), Gaps = 11/174 (6%)
Query: 46 EPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPS 105
E ++ P++D S+ + T S R ++ +R S S
Sbjct: 1295 ESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSV-SYSHSRSRSRSSTSSYRSRSY 1353
Query: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSF---SKKRRHSSSSPKSK 162
SR + + S + R RSSSY K + SS+ R S+ S+ R ++ S S+
Sbjct: 1354 SRSRSRGWYSRGRTRSRSSSYRS---YKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSR 1410
Query: 163 RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQK 216
R R ++ +S+ R C RS S+S S H RSP E +
Sbjct: 1411 SRSRSRSQRSDSYHRGRSYNRRSRSC--RSYGSDSESDRSYSHH--RSPSESSR 1460
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 101 bits (252), Expect = 2e-21
Identities = 147/535 (27%), Positives = 202/535 (37%), Gaps = 119/535 (22%)
Query: 106 SRGKKKKKKSTRKKRRRSSS-------YSPSPVKKKKKKSSKKHKRRRS----------- 147
SR K + K T K + SS P K K+ +K R
Sbjct: 579 SRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSA 638
Query: 148 -FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRH 206
++ S S+ D R + R KSHRH+ + +S S R ++
Sbjct: 639 CSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKS-SKHKRKHKADTEE 697
Query: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPS-QPLQMLGYLSARGVITGSGSAA 265
+ E G+KS++R R+ K K S A S R P +P GSGS A
Sbjct: 698 KSSKAESGEKSKKRKKRKRKKN--KSSAPADSERGPKPEP-------------PGSGSPA 742
Query: 266 DLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSG 325
R R+Q+ S RS E+GS SG
Sbjct: 743 P---------PRRRRRAQD--------------DSQRRSLPAEEGS------------SG 767
Query: 326 NTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSP--CLECAEVKKSSLVPSTARS 383
+ G SS Q+ G GR+ +G P C A K+SS S+ RS
Sbjct: 768 KKDEGGGG---SSSQDHG-----------GRKHKGELPPSSCQRRAGTKRSSR--SSHRS 811
Query: 384 SPMKGCSRSSSYASTR-----SSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSP--SYS 436
P G S +S R S +S + +++SRS S + S RS SYS
Sbjct: 812 QPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYS 871
Query: 437 SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKR 496
S S S S SR +RS S YS +R ++S++ + + A + RS KR
Sbjct: 872 SSSDASSDQSCYSR-QRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS-----KR 925
Query: 497 RRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRS 556
+ S S + Y S S S S S + ++ SRS RS S S SRS
Sbjct: 926 HKYSSSDDD--------------YSLSCSQSRSRSRS---HTRERSRSRGRSRSSSCSRS 968
Query: 557 RSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
RS+RRSR+ T+ S RSRS RS SR +S + S + S RR
Sbjct: 969 RSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRR 1023
Score = 77.4 bits (189), Expect = 4e-14
Identities = 112/442 (25%), Positives = 170/442 (38%), Gaps = 50/442 (11%)
Query: 70 EPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPS 129
EP G++ E + T R L + + S S KKKKK + + + + +
Sbjct: 646 EPGGSHGSETEDTGRSLPSKKERSGK----------SHRHKKKKKHKKSSKHKRKHKADT 695
Query: 130 PVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCP 189
K K +S +K K+R+ K++++ SS+P R K S S P R R +
Sbjct: 696 EEKSSKAESGEKSKKRKK-RKRKKNKSSAPADSERGPKPEPPGSGS-PAPPRRRRRAQDD 753
Query: 190 SRSQSSESRPSSCESRHRGRSPEEGQ-KSRRRHSRRCSKTLCK---DSPEAQSSRPPSQP 245
S+ +S + S + G Q R+H + C+ + + S SQP
Sbjct: 754 SQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQP 813
Query: 246 LQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSR 305
S+ + S+ L K+ S + +E DSG++ S RSR
Sbjct: 814 -------SSGDEDSDDASSHRLHQKSPSQYSE---EEEEEDSGSEHS----------RSR 853
Query: 306 GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPC 365
+ S S R +S + + S S + + S SR R S
Sbjct: 854 SRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS-- 911
Query: 366 LECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHS-SRSPNPRASPRYTQSRSTS- 423
S S RS K S Y+ + S S S SRS S +SRS+S
Sbjct: 912 ------DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSC 965
Query: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERA 483
S RS RS S ++ S +RS RSR + S S+ S SR+R + + + R
Sbjct: 966 SRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDF 1025
Query: 484 RRRR--RSYSP--MRKRRRDSP 501
R + RS SP R R + P
Sbjct: 1026 IRSKIYRSQSPHYFRSGRGEGP 1047
Score = 40.0 bits (92), Expect = 0.006
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 35/195 (17%)
Query: 89 TRGHSASHDKDLTPPPSSRGKKKKKKSTRKK-----RRRSSSYSPSPVKKKKKKSSKKH- 142
++ H S D S+ + + + TR++ R RSSS S S K++ +S+ H
Sbjct: 923 SKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSR-SKRRSRSTTAHS 981
Query: 143 -KRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
+R RS+S+ R S+ SP +R R + P + H R S+ S+S P
Sbjct: 982 WQRSRSYSRDRSRSTRSP--SQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQS-PHY 1038
Query: 202 CESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGS 261
S GR G+K R +++++ PPSQ + TG
Sbjct: 1039 FRS---GRGEGPGKKDDGR------------GDDSKATGPPSQ---------NSNIGTGR 1074
Query: 262 GSAADLFTKTASPLT 276
GS D + + +T
Sbjct: 1075 GSEGDCSPEDKNSVT 1089
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 99.8 bits (247), Expect = 7e-21
Identities = 99/319 (31%), Positives = 136/319 (42%), Gaps = 21/319 (6%)
Query: 296 STQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRG 355
S S +RSR K G SKS S + S SG S ++K S+
Sbjct: 190 SHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG-----SRSRSKSRSRSQSRSRSKK 244
Query: 356 RESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPR 415
+SR SP E + + S S ++S K + + SRSP+ S
Sbjct: 245 EKSR---SPSKEKSRSRSHSAGKSRSKS---KDQAEEKIQNNDNVGKPKSRSPSRHKSK- 297
Query: 416 YTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDS 475
++SRS S E+R S+ + R SRSR S SR R ++
Sbjct: 298 -SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKG 356
Query: 476 QQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSS 535
++R RE +R R RS S + R+ + +K+ S S S S+S
Sbjct: 357 RKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKERE 416
Query: 536 WYSSSSSRSASRSYSRS-------RSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR 588
S SS+ R S + RSRSRS +S+ S S SRS S S++RSRS+SR
Sbjct: 417 HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS-ASKTRSRSKSR 475
Query: 589 SRSRSRSQSRSYSSADSYS 607
SRS SRS SRS S + S S
Sbjct: 476 SRSASRSPSRSRSRSHSRS 494
Score = 94.0 bits (232), Expect = 4e-19
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 37/267 (13%)
Query: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSS-HS----SRSPNPRASPRYTQSRSTS--- 423
+K LV S + SRS S++ +RS S HS SRS + ++S ++SRS S
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 424 --SEKRSYSRSPSYSSKSGKRSPPSRSSRSR-RSPSYSRYSPSRERDPKYSEKDSQQRER 480
S+ RS S+S S S K RSP SRSR S SR + + K D+ + +
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 481 ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSS 540
R+ R +S S R R ++ RR+ ++ + R S S S S
Sbjct: 288 SRSPSRHKSKSKSRSRSQE-------RRVEEEKRGSVSRGRSQEKSLRQSRSRSR--SKG 338
Query: 541 SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSR-----------------S 583
SRS SRS S+S+ + + R+RSR + S S SRS S SR R
Sbjct: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
Query: 584 RSRSRSRSRSRSQSRSYSSADSYSSTR 610
RS+SRS SRS S+ A S SS R
Sbjct: 399 TDRSQSRSPSRSVSKEREHAKSESSQR 425
Score = 91.7 bits (226), Expect = 2e-18
Identities = 104/332 (31%), Positives = 147/332 (44%), Gaps = 48/332 (14%)
Query: 304 SRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQS 363
SR + S S S+SR + + S ++ S +K SR R G +S
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK----------SRSRSRSGSRS 228
Query: 364 PCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQS-RST 422
+ S S +RS K SRS S +RS SHS+ ++ + + ++
Sbjct: 229 --------RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 280
Query: 423 SSEKRSYSRSPS-YSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERE 481
+ + SRSPS + SKS RS S+ RR R S SR R + S + S+ R R
Sbjct: 281 DNVGKPKSRSPSRHKSKSKSRS----RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336
Query: 482 ------RARRRRRSYSPM--RKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSST 533
R+R R +S RKR R+ R S R R R S + S S
Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS-SKKKK 395
Query: 534 SSWYSSSSSRSASRSYSRSRSRSRSRRRSR--------------TRTSSSSSSRS-PSPG 578
S SRS SRS S+ R ++S R TR+ S S+S+S P+
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
Query: 579 SRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
S SRSRS+S S++RSRS+SRS S++ S S +R
Sbjct: 456 SESRSRSKSASKTRSRSKSRSRSASRSPSRSR 487
Score = 86.3 bits (212), Expect = 8e-17
Identities = 84/297 (28%), Positives = 127/297 (42%), Gaps = 14/297 (4%)
Query: 272 ASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSG 331
+S + S+ RS+ S S S +RS+ ++ SPS S+SR ++G +
Sbjct: 210 SSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
Query: 332 NSFTTSSPQNKGAMLENLS-PTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCS 390
QN +N+ P SR +S ++ ++ V R S +G S
Sbjct: 270 KDQAEEKIQNN----DNVGKPKSRSPSRHKSKSKSRSRSQERR---VEEEKRGSVSRGRS 322
Query: 391 RSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSR 450
+ S +RS S S R+ R KRS S S S+S +S SR
Sbjct: 323 QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS-RSRSRSKSERSRKRG 381
Query: 451 SRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRIT 510
S+R ++ D S+ S R + R +S S R+ R +S + + T
Sbjct: 382 SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGES-ENAGTNQET 440
Query: 511 SARKRPIPYYRPS-PSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRT 566
+R R +P+ PS S S S ++S + SRS SRS S SRS SRSR RS +R+
Sbjct: 441 RSRSRSNSKSKPNLPSESRSRSKSAS---KTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 84.3 bits (207), Expect = 3e-16
Identities = 99/365 (27%), Positives = 148/365 (40%), Gaps = 40/365 (10%)
Query: 108 GKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEK 167
G+K + + RR SYS S + + S+ ++ RS S + S S +S+ R
Sbjct: 167 GRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGS 226
Query: 168 RHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSK 227
R + +SRSR + R + + SRS S E S S + RS + Q + +
Sbjct: 227 RSRSKSRSRSQSRSRSKKEK--SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQN----- 279
Query: 228 TLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDS 287
D+ SR PS+ + + + + + SRGRSQE
Sbjct: 280 ---NDNVGKPKSRSPSR---------HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL 327
Query: 288 GNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLE 347
S S S +RSR + SKS++ G S + S ++K
Sbjct: 328 RQSRSRSRSKGGSRSRSRSR---------SKSKDKRKGRKRSREESRSRSRSRSK----- 373
Query: 348 NLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRS 407
S SR R S+ S + KK S +R SP + S+ +A + SS R
Sbjct: 374 --SERSRKRGSKR-DSKAGSSKKKKKEDTDRSQSR-SPSRSVSKEREHAKSESSQREGRG 429
Query: 408 PNPRA-SPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRER 466
+ A + + T+SRS S+ K S PS S K + +RS RS S SR SPSR R
Sbjct: 430 ESENAGTNQETRSRSRSNSK-SKPNLPSESRSRSKSASKTRSRSKSRSRSASR-SPSRSR 487
Query: 467 DPKYS 471
+S
Sbjct: 488 SRSHS 492
Score = 73.9 bits (180), Expect = 4e-13
Identities = 101/394 (25%), Positives = 155/394 (39%), Gaps = 65/394 (16%)
Query: 38 ARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHS-ASH 96
A + L TE + +D P + + + + S R + R+ + G S +SH
Sbjct: 156 ALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSH 215
Query: 97 DKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSS 156
K SR + + +R K R S S S S KK+K +S K K S+ R HS+
Sbjct: 216 SK-------SRSRSRSGSRSRSKSR-SRSQSRSRSKKEKSRSPSKEK-----SRSRSHSA 262
Query: 157 SSPKSKRRDEKRHKKQSRSR--PRKSHRHRHHRCPSRSQS-SESRPSSCESR---HRGRS 210
+SK +D+ K Q+ KS H+ S+S+S S+ R E R RGRS
Sbjct: 263 GKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRS 322
Query: 211 PEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTK 270
E+ + R SR S SR S+
Sbjct: 323 QEKSLRQSRSRSR---------SKGGSRSRSRSR-------------------------S 348
Query: 271 TASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDS 330
+ R RS+E S +++ +R RG ++ S +G K ++ D+
Sbjct: 349 KSKDKRKGRKRSREESRSRSRS---RSKSERSRKRGSKRDSKAGSSKKKKK------EDT 399
Query: 331 GNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSS-PMKGC 389
S + S ++ E+ S RE RG E + S S ++ + P +
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR 459
Query: 390 SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTS 423
SRS S + TRS S SRS + SP ++SRS S
Sbjct: 460 SRSKSASKTRSRS-KSRSRSASRSPSRSRSRSHS 492
Score = 67.0 bits (162), Expect = 5e-11
Identities = 83/259 (32%), Positives = 111/259 (42%), Gaps = 49/259 (18%)
Query: 387 KGCSRSSSYASTRSSSHSSRSPNPRASP----RYTQSRSTSSEKRSYSRSPSYSSKSGK- 441
+G R SY S RS RS + P Y S + S+ Y ++G+
Sbjct: 71 RGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEV 130
Query: 442 -RSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQR-----ERERARRRRRSYSPMRK 495
+ + ++ + YS + K + R E + RRRRSYS R
Sbjct: 131 TYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSR- 189
Query: 496 RRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSR 555
SH +R +R R + R S S SGS S+ S S S SRS SRS S+SRSR
Sbjct: 190 ------SHSRSR----SRSR---HSRKSRSRSGSSKSSHS-KSRSRSRSGSRSRSKSRSR 235
Query: 556 SRSRRRSRTRTSSSSS-----SRSPSPG-SRSRSR-----------------SRSRSRSR 592
S+SR RS+ S S S SRS S G SRS+S+ SRS SR +
Sbjct: 236 SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK 295
Query: 593 SRSQSRSYSSADSYSSTRR 611
S+S+SRS S +R
Sbjct: 296 SKSKSRSRSQERRVEEEKR 314
Score = 51.2 bits (121), Expect = 3e-06
Identities = 40/128 (31%), Positives = 66/128 (51%), Gaps = 12/128 (9%)
Query: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRR---RSFSKKRRHSSS-SPKS 161
SR + K ++S ++ +R S S KKKKK+ + + + R RS SK+R H+ S S +
Sbjct: 368 SRSRSKSERSRKRGSKRDSKAGSS--KKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425
Query: 162 KRRDEKRH---KKQSRSRPRKSHRHRHH---RCPSRSQSSESRPSSCESRHRGRSPEEGQ 215
+ R E + +++RSR R + + + + SRS+S+ S +SR R S +
Sbjct: 426 EGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSR 485
Query: 216 KSRRRHSR 223
R HSR
Sbjct: 486 SRSRSHSR 493
Score = 39.3 bits (90), Expect = 0.011
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 60 SEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSS----RGKKKKKKS 115
S K G ++ + +++ T R + S S +++ SS RG+ + +
Sbjct: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
Query: 116 TRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRS 175
++ R RS S S K K S+ R +S SK R S S +S R R + +S S
Sbjct: 437 NQETRSRSRSNS----KSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
Query: 176 R 176
R
Sbjct: 493 R 493
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 95.5 bits (236), Expect = 1e-19
Identities = 137/525 (26%), Positives = 193/525 (36%), Gaps = 72/525 (13%)
Query: 98 KDLTPPPSSRGKKKKKKSTRK-KRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSS 156
+D + SR KKKK K K K+ + SS K K K KKHKR+ +
Sbjct: 33 EDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGM 92
Query: 157 SSPKSKRRD-----EKRHKKQSRSRPRKSHRHRHHRCPSRS----QSSESRPSSCESRHR 207
S K + D E K+++ + + + S Q ES S E
Sbjct: 93 SPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYES--GSEEEGEI 150
Query: 208 GRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITG------- 260
G +S R S K D+ R S+ + + S + G
Sbjct: 151 HEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKE 210
Query: 261 --SGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQT-SSARSRGQEK-----GSP 312
+ S + K+ SP S+ + Q S + T S + ARS +K S
Sbjct: 211 KTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSK 270
Query: 313 SGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVK 372
S KS +N + D G + SP + L S+ R SR + K
Sbjct: 271 SKDRKKSPIINESRSRDRGKK--SRSPVD-------LRGKSKDRRSRSKERKSKRSETDK 321
Query: 373 KSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRS 432
+ + S ++ + +RS S RS S SP PR R ++S + + S+S
Sbjct: 322 EKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKS 381
Query: 433 PSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERAR-------- 484
PS + G+R+ R RR P R S R R +D RER++
Sbjct: 382 PSRTLSPGRRAKSRSLERKRREPERRRLSSPRTR-----PRDDILSRRERSKDASPINRW 436
Query: 485 --RRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSS 542
RRRS SP+R+R R SP RR S R+R S S
Sbjct: 437 SPTRRRSRSPIRRRSR-SP----LRRSRSPRRR----------------SRSPRRRDRGR 475
Query: 543 RSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRS 587
RS SR RSRSR RRRSR++ S S G + S S
Sbjct: 476 RSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSS 520
Score = 94.0 bits (232), Expect = 4e-19
Identities = 140/555 (25%), Positives = 218/555 (39%), Gaps = 87/555 (15%)
Query: 93 SASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKR 152
+A+ + L P +K + S S + + KKK KHK R SK +
Sbjct: 2 AAAETQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKK---KHKHR---SKHK 55
Query: 153 RHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSP- 211
+H SS + K +K+HK + H+H+ H+ +S+ S R +
Sbjct: 56 KHKHSSEEDK---DKKHKHK--------HKHKKHKRKEIIDASDKEGMSPAKRTKLDDLA 104
Query: 212 --EEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269
E+ +K R L + ++ L + GY S A
Sbjct: 105 LLEDLEKQRALIKAELDNELMEGKVQS------GMGLILQGYESGSEEEGEIHEKARNGN 158
Query: 270 KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSD 329
++++ ++++G+ + D+ T +++ +K GG+ +E + + S
Sbjct: 159 RSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSK 218
Query: 330 SGNSFTTSSPQNKGA--MLENLSPTSRGRESRGF---QSPCLECAEVKKSSLVPSTARSS 384
+ S ++K ++ SPT R R +SP + +++ S + S
Sbjct: 219 ERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSK-SKDRKKS 277
Query: 385 PMKGCSRSSSYASTRSSSHSSRSP----------NPRASPRYTQSRSTSSEKRSYSRSPS 434
P+ SRS R SRSP R+ R ++ T EK+ +SPS
Sbjct: 278 PIINESRS------RDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPI-KSPS 330
Query: 435 YSSKSGK--RSPPSRSSRSRRSPSYS---RYSPSRERDPKYSEKDSQQRERERAR----R 485
+ SGK RSP R RS + S S R R R P +++ S+Q + R
Sbjct: 331 KDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGR 390
Query: 486 RRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA 545
R +S S RKRR E RR++S R RP S S + W
Sbjct: 391 RAKSRSLERKRREP-----ERRRLSSPRTRPRDDILSRRERSKDASPINRW--------- 436
Query: 546 SRSYSRSRSRSRSRRRSRTRT----SSSSSSRSPSP-----GSRSRSRSRSRSRSRS--R 594
S +R RSRS R R+R+ S S RS SP G RSRSR R RSRSR R
Sbjct: 437 ----SPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRR 492
Query: 595 SQSRSYSSADSYSST 609
+SRS D + +
Sbjct: 493 RRSRSKVKEDKFKGS 507
Score = 73.6 bits (179), Expect = 5e-13
Identities = 112/443 (25%), Positives = 176/443 (39%), Gaps = 21/443 (4%)
Query: 111 KKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHK 170
+K ++ + RSSS K ++KK + RS ++ RH S KSK E +
Sbjct: 152 EKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRS-KERTRHRSDKKKSKGGIEIVKE 210
Query: 171 KQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLC 230
K +RS+ ++ +S+S R S + + +SP ++S+ + + S T
Sbjct: 211 KTTRSKSKER---------KKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDD 261
Query: 231 KDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGND 290
K E +S + ++ +R S S DL K+ + S+ R + S D
Sbjct: 262 KVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKR-SETD 320
Query: 291 TSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQ-NKGAMLENL 349
P S S G+E SPS +S + S + S + SP N ++
Sbjct: 321 KEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSK 380
Query: 350 SPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPN 409
SP+ R +S LE + S+ R+ P S S +S + SP
Sbjct: 381 SPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDIL-SRRERSKDASPINRWSPT 439
Query: 410 PRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR---RSPSYS---RYSPS 463
R S + RS S +RS RSP S+S +R R SRSR RS S R S S
Sbjct: 440 RRRSRSPIRRRSRSPLRRS--RSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRS 497
Query: 464 RERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPS 523
+ ++ K+ S+ + E+ + D + +E RRI Y
Sbjct: 498 KVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAE 557
Query: 524 PSSSGSLSSTSSWYSSSSSRSAS 546
S+ S SS SS+ +RS S
Sbjct: 558 DSNMSVPSEPSSPQSSTRTRSPS 580
Score = 56.2 bits (134), Expect = 8e-08
Identities = 45/152 (29%), Positives = 62/152 (40%), Gaps = 6/152 (3%)
Query: 78 ERDKTCRELGATRGHS--ASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKK 135
+R +T +E + S AS K+ P G+ K++S K R S S SP+ +
Sbjct: 315 KRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDR 374
Query: 136 KKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR----CPSR 191
+ K R +R S S + +R E+R R+RPR R R P
Sbjct: 375 RSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPIN 434
Query: 192 SQSSESRPSSCESRHRGRSPEEGQKSRRRHSR 223
S R S R R RSP +S RR SR
Sbjct: 435 RWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSR 466
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/240 (19%), Positives = 89/240 (37%), Gaps = 45/240 (18%)
Query: 417 TQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYS---EK 473
TQS E + S + ++G+ S ++ R S+ + K+S +K
Sbjct: 6 TQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDK 65
Query: 474 DSQQRERERARRRRRS----------YSPMRKRRRDSPSHLE------------------ 505
D + + + + ++ +R SP ++ + D + LE
Sbjct: 66 DKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELM 125
Query: 506 ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS--------------RSYSR 551
++ S + Y G + + + SS+RS+S + S+
Sbjct: 126 EGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSK 185
Query: 552 SRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
SRS+ R+R RS + S +RS+S+ R +S+S S+ + S S T R
Sbjct: 186 SRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLR 245
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 90.1 bits (222), Expect = 5e-18
Identities = 129/586 (22%), Positives = 211/586 (36%), Gaps = 88/586 (15%)
Query: 52 VVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKK 111
++P E+ +H ++ ++S + D + + S+S D + KK+
Sbjct: 177 LIPKSKVKKEEKKRHKSSSSSSSSSSDSDSS------SDSQSSSDSSDSESATEEKSKKR 230
Query: 112 KKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDE----- 166
KKK + R+ KK+KK KK K+ S + + + P+S R E
Sbjct: 231 KKKHRKNSRKH----------KKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPI 280
Query: 167 --------KRHKKQSRSRPRKSHRHRHHRC-PSRSQSSESRPSSCESRHRGRSPEEGQKS 217
K K + R R C P SQ + + +R + G +
Sbjct: 281 PENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRR 340
Query: 218 RRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAA-DLFTKTASPLT 276
R SR S+ + S R Q Q + S I G S ++ SP+
Sbjct: 341 YRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV- 399
Query: 277 TSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDS------ 330
R + ++ + S P+ + + K + SK R++ + D
Sbjct: 400 --RVKERKITDHRNVSESPNRKNEKEKKVKDHKSN-----SKERDIRRNSEKDDKYKNKV 452
Query: 331 ---GNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMK 387
S + S + K E S +R E R ++ + V + S K
Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKHNRNEEKR-----MRSRSKGRDHENVKEKEKQSDSK 507
Query: 388 GCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSR 447
G + S + +S S+S + S+S ++R+ SRS GK S SR
Sbjct: 508 GKDQERSRSKEKSKQLESKSNE------HDHSKSKEKDRRAQSRSRECDITKGKHSYNSR 561
Query: 448 SSRSRRSPSYSRYSPSRERDP---------KYSEKDSQQRERERARRRR----RSYSPMR 494
+ RS SR SR D +Y E++ ++R R R+R RR RS S R
Sbjct: 562 TRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDR 621
Query: 495 KRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSR- 553
+RRR E S K YR S S + +S S R YS+SR
Sbjct: 622 RRRRRDSRSSEREESQSRNK---DKYRNQESKSS--------HRKENSESEKRMYSKSRD 670
Query: 554 ----SRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595
+ SR ++ R ++ S +S S +++ + RS
Sbjct: 671 HNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRS 716
Score = 90.1 bits (222), Expect = 5e-18
Identities = 123/533 (23%), Positives = 209/533 (39%), Gaps = 64/533 (12%)
Query: 104 PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSS-----KKHKRRRSFSKKRRHSSSS 158
P S+ KK++KK + SSS S S + SS + +S +K++H +S
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 159 PKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGR-SPEEGQKS 217
K K+ +KR KK +S +S P + E P E+R R SP + +
Sbjct: 239 RKHKKEKKKR-KKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEK 297
Query: 218 RRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPL-- 275
R++ R E + + P SQP R ++T SG K P
Sbjct: 298 ERKNRER--------ERERECNPPNSQPASY----QRRLLVTRSGRKI----KGRGPRRY 341
Query: 276 -TTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPS----GGLSKSRELNSGNTSD- 329
T SR RS++ ++T PP + R++ S G S+ E+ S
Sbjct: 342 RTPSRSRSRDRFRRSET--PPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV 399
Query: 330 -------SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTAR 382
+ + + SP K + + + R +++++S +
Sbjct: 400 RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKER----------DIRRNSEKDDKYK 449
Query: 383 SSPMKGC-SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGK 441
+ K S+S S + +S S S + R + +SRS + + S GK
Sbjct: 450 NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509
Query: 442 RSPPSRSS-RSRRSPSYSR---YSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRR 497
SRS +S++ S S +S S+E+D + ++ S++ + + + S + R R
Sbjct: 510 DQERSRSKEKSKQLESKSNEHDHSKSKEKDRR-AQSRSRECDITKGKHSYNSRTRERSRS 568
Query: 498 RDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSR 557
RD + +R R R Y+R S SR RSRS+ R
Sbjct: 569 RDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGR-------SRSRERRTPPGRSRSKDR 621
Query: 558 SRRRSRTRTSSSSSSRSPSPGS-RSRSRSRSRSRSRSRSQSRSYSSADSYSST 609
RRR +R+S S+S + R++ S + S S+ R YS + ++S+
Sbjct: 622 RRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSS 674
Score = 78.2 bits (191), Expect = 2e-14
Identities = 112/498 (22%), Positives = 191/498 (38%), Gaps = 43/498 (8%)
Query: 137 KSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSE 196
++ K + F++ R S K + +K KK+ +S S S SQSS
Sbjct: 155 ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSS- 213
Query: 197 SRPSSCESRHRGRSPEEGQKSR---RRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLS 253
S S ES +S + +K R R+H + K K S ++ SS ++ L+ +
Sbjct: 214 SDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKR--KKSKKSASSESEAENLEAQPQST 271
Query: 254 ARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSR--GQEKGS 311
R + + P + R +PP++Q +S + R G
Sbjct: 272 VRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGR 331
Query: 312 PSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEV 371
G R + + +P + ++ R + E E+
Sbjct: 332 KIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEI 391
Query: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR 431
K++ + SP++ R + S S + ++ + + + +R+ +
Sbjct: 392 KEN-------QRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEK 444
Query: 432 SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYS 491
Y +K KR+ S+S+ S S+ERD K++ + +R R+R + R +
Sbjct: 445 DDKYKNKVKKRAKSKSRSKSKEK------SKSKERDSKHNR---NEEKRMRSRSKGRDHE 495
Query: 492 PMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA------ 545
++++ + S S + + + ++++ S S S + S SR
Sbjct: 496 NVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGK 555
Query: 546 ----SRSYSRSRSRSRSRR-RSRT----RTSSSSSSRSPSPGSRSRSRSRSRSR----SR 592
SR+ RSRSR RSRR RSRT R+ S R R R RSRSR R R
Sbjct: 556 HSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGR 615
Query: 593 SRSQSRSYSSADSYSSTR 610
SRS+ R DS SS R
Sbjct: 616 SRSKDRRRRRRDSRSSER 633
Score = 53.9 bits (128), Expect = 4e-07
Identities = 81/415 (19%), Positives = 146/415 (35%), Gaps = 90/415 (21%)
Query: 98 KDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSS 157
++++ P+ + +K+KK K + + K K K+ K +R+ SK R S
Sbjct: 410 RNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVK---KRAKSKSRSKSKE 466
Query: 158 SPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKS 217
KSK RD K ++ + + +S H + + S+S+ G+
Sbjct: 467 KSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSK---------------GKDQ 511
Query: 218 RRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTT 277
R S+ SK L S E S+ +K
Sbjct: 512 ERSRSKEKSKQLESKSNEHDHSK----------------------------SKEKDRRAQ 543
Query: 278 SRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTS 337
SR R + G + + + + S +R R + S + +SR S + +
Sbjct: 544 SRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSR-------SKEYHRYREQ 596
Query: 338 SPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAS 397
+ +G SR RE R P +RS + R S +S
Sbjct: 597 EYRRRG--------RSRSRERR----------------TPPGRSRSKDRRR-RRRDSRSS 631
Query: 398 TRSSSHSSRSPNPRASPRYTQSR--STSSEKRSYSRSPSYSSKSGKR--------SPPSR 447
R S S R + R ++ SEKR YS+S ++S + R SP S+
Sbjct: 632 EREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSK 691
Query: 448 SSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPS 502
+S + + D K + S ++E ++++ + + + ++ D S
Sbjct: 692 IKQSSQDNELKSSMLKNKEDEKI--RSSVEKENQKSKGQENDHVHEKNKKFDHES 744
Score = 53.1 bits (126), Expect = 7e-07
Identities = 59/268 (22%), Positives = 108/268 (40%), Gaps = 46/268 (17%)
Query: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
+E ++ + H+++ SR K + ++ ++K ++S S +++ +S +K K
Sbjct: 465 KEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKD---QERSRSKEKSK 521
Query: 144 RRRSFSKKRRHSSSSPKSKRRDEK---------RHKKQSRSRPRKSHRHRHHRCPSR--- 191
+ S S + HS S K +R + +H SR+R R R R R SR
Sbjct: 522 QLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHD 581
Query: 192 ---SQSSE-SRPSSCESRHRGRS--------PEEGQKSRRRHSRRCSKTLCKDSPEAQ-- 237
S+S E R E R RGRS P + RR RR S++ ++ +++
Sbjct: 582 RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNK 641
Query: 238 ----------SSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYD- 286
S R + + Y +R + + S + SP + + SQ+ +
Sbjct: 642 DKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNEL 701
Query: 287 ------SGNDTSSPPSTQTSSARSRGQE 308
+ D S + + +S+GQE
Sbjct: 702 KSSMLKNKEDEKIRSSVEKENQKSKGQE 729
Score = 37.0 bits (84), Expect = 0.053
Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 38/153 (24%)
Query: 90 RGHSASHDKDLTPPPSSRGK-KKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKR---- 144
RG S S ++ TPP SR K +++++ + R S S + K + ++S H++
Sbjct: 601 RGRSRSRERR-TPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 145 --RRSFSKKRRHSSS------------SPKSK-----------------RRDEK-RHKKQ 172
+R +SK R H+SS SP SK + DEK R +
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVE 719
Query: 173 SRSRPRKSHRHRHHRCPSRSQSSESRPSSCESR 205
++ K + H ++ ES P + E +
Sbjct: 720 KENQKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 89.7 bits (221), Expect = 7e-18
Identities = 122/538 (22%), Positives = 184/538 (34%), Gaps = 58/538 (10%)
Query: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
GHS SH T +SRG+ + ++R R S S + S +H S
Sbjct: 865 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGS------RHSGSRHHEASS 918
Query: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR----PSSCE 203
+ RHS + + + + ++Q S + S H R S SR + +
Sbjct: 919 HADISRHSQAG-QGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQ 977
Query: 204 SRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGS 263
SRH R P + R H + +P A++S S+ G GS
Sbjct: 978 SRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRH 1037
Query: 264 AADLFTKTASPLTTSRGRSQEYDSGNDTSS----------PPSTQTSSARSRGQEKGSPS 313
+ S + + S DSG+ SS + T S GQ+
Sbjct: 1038 QQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQ 1097
Query: 314 GGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKK 373
+R+ + G + SG+ S + + TS GR + +
Sbjct: 1098 SHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSA 1157
Query: 374 SSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSP 433
S T R+ P S R SH +S + R S S S S RS
Sbjct: 1158 SQEGQDTIRAHP-------GSRRGGRQGSHHEQSVD-----RSGHSGSHHSHTTSQGRSD 1205
Query: 434 SYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKY---SEKDSQ-QRERERARRRRRS 489
+ +SG RS ++ + ++S SR+S SR + S + SQ +E+ R R
Sbjct: 1206 ASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRH 1265
Query: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR-- 547
+ DS H + S SGS S S SR SR
Sbjct: 1266 QGSSVSQDSDSERHSD----------------DSERLSGSASRNHHGSSREQSRDGSRHP 1309
Query: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
+ + S +R S + + S S G S ++RS R SR SADS
Sbjct: 1310 GFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADS 1367
Score = 82.8 bits (203), Expect = 8e-16
Identities = 121/515 (23%), Positives = 197/515 (38%), Gaps = 52/515 (10%)
Query: 118 KKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRP 177
++ R S S S V + + +++ + + S ++KRR S S+ RD + H + S
Sbjct: 258 ERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRR---GSRVSQDRDSEGHSEDSERHS 314
Query: 178 RKSHRHRHHRCPSRSQSSESRPSSCESRH--RGRSPEEGQKSRRRHSRRCSKTLCKDSPE 235
+ R+ H +S+ P S + G S + ++S RH+ S+ S E
Sbjct: 315 GSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHE 374
Query: 236 AQSSRPPSQ--PLQMLGYLSARGVITGSGSAADLFT------KTASPLTTSRGRSQEYD- 286
S P + S+R TG G A+ + + S + S G S+ D
Sbjct: 375 QARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDT 434
Query: 287 ---SGNDTSS-PPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFT-TSSPQN 341
SG+ + + S R R E+ SG S ++++ DS + T TS+
Sbjct: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRSG--SSLYQVSTHEQPDSAHGRTGTSTGGR 492
Query: 342 KGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSS 401
+G+ E +SR S+ Q P ++R S S S
Sbjct: 493 QGSHHEQARDSSRHSASQEGQDTIRGH---------PGSSRGGRQGSHHEQSVNRSGHSG 543
Query: 402 SHSSRSPNPR---ASPRYTQSRSTSSEKRSYSRSPSYSSKSGKR--SPPSRSSRSRRS-- 454
SH S + + AS + SRS S + R+ +S + SG R S++ SR S
Sbjct: 544 SHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQV 603
Query: 455 -------PSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEAR 507
P SR S S+ S+ ER R + +++ RD H +
Sbjct: 604 GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSH 663
Query: 508 RITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTS 567
A S+ S S + +SSS A+ S+ ++RS + R SR +
Sbjct: 664 HEDRAGH--------GHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQ 715
Query: 568 SSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
S+ SSR G S + S R S S++ S
Sbjct: 716 SADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDS 750
Score = 82.0 bits (201), Expect = 1e-15
Identities = 122/537 (22%), Positives = 183/537 (34%), Gaps = 56/537 (10%)
Query: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
GHS SH T +SRG+ + ++R R S S + S +H +
Sbjct: 2810 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGS------RHSGSRHHEAST 2863
Query: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR----PSSCE 203
+ RH S + + + +R ++Q S + S H R S SR + +
Sbjct: 2864 HADISRH-SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQ 2922
Query: 204 SRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGS 263
R R P Q+ R H + + Q+S S+ G GS
Sbjct: 2923 LRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHH 2982
Query: 264 AADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELN 323
+ S + + S DSG+ S + S + S S
Sbjct: 2983 QQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQ 3042
Query: 324 SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARS 383
S S G S TS + G+ L +S + S G+ P + + ++R
Sbjct: 3043 SHQESARGRSGETSG--HSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRH 3100
Query: 384 SPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTS-------SEKRSYSRSPSYS 436
S +S Y H S R + S +S S S RS +
Sbjct: 3101 S-------ASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASR 3153
Query: 437 SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQ-----QRERERARRRRRSYS 491
+SG RS + +S SR+S SR + S+ Q + E +RR RR S
Sbjct: 3154 GQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGS 3213
Query: 492 PMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR 551
+ + DS H E S SGS S SR SR + R
Sbjct: 3214 SV-SQDSDSEGHSE----------------DSERWSGSASRNHRGSVQEQSRHGSR-HPR 3255
Query: 552 SRSRSRS---RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
S R+ R+R S + + + S G + S ++RS R SR SADS
Sbjct: 3256 SHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS 3312
Score = 78.6 bits (192), Expect = 2e-14
Identities = 128/553 (23%), Positives = 190/553 (34%), Gaps = 59/553 (10%)
Query: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
GHS H TP +S G+ + ++R+ R S S + S +H +
Sbjct: 1513 GHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGS------RHSGSRHHEPST 1566
Query: 148 FSKKRRHS------SSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
+ RHS S+ K+ RR + S R SR+ +R
Sbjct: 1567 RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSARE-- 1624
Query: 202 CESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGS 261
+SRH R+P Q+ R H + + A++S S+ G GS
Sbjct: 1625 -QSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGS 1683
Query: 262 GSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSG------- 314
+ T S + S DSGN SS S S + S S
Sbjct: 1684 RHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPH 1743
Query: 315 --GLSKSRELNSGNTSDSGNSFT--TSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAE 370
+S SG S SF S+ + + P++ GR+ R + +
Sbjct: 1744 QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQ-RSRHEQARDSSR 1802
Query: 371 VKKSSLVPSTARSSP--MKGCSRSSSY-----ASTRSSSHSSRSPNPRASP---RYTQSR 420
S T R P +G + S Y +S S SH S + + S + SR
Sbjct: 1803 HSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR 1862
Query: 421 STSSEKRSYSRSPSYSSKSGKR--SPPSRSSRSRRS---------PSYSRYSPSRERDPK 469
S S + R+ +S S SG R SR+ SR S P SR S
Sbjct: 1863 SVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDS 1922
Query: 470 YSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGS 529
S+ S+ ER R ++ RD H + A S+ S
Sbjct: 1923 DSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGH--------GHSADSS 1974
Query: 530 LSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRS 589
S + SSS A+ S+ ++RS + R S + S+ SSR G S + S
Sbjct: 1975 RQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDS 2034
Query: 590 RSRSRSQSRSYSS 602
R S S++ S
Sbjct: 2035 GHRGYSGSQASDS 2047
Score = 74.7 bits (182), Expect = 2e-13
Identities = 128/550 (23%), Positives = 189/550 (34%), Gaps = 82/550 (14%)
Query: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
GHS SH T +SRG+ + ++RK + S S + S H S
Sbjct: 2162 GHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGS------RHSGSHHHEASS 2215
Query: 148 FSKKRRHS------SSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
++ RHS SS P++ SRPR S + S+ SE R S
Sbjct: 2216 WADSSRHSLVGQGQSSGPRT-------------SRPRGSSVSQDSDSEGHSEDSERRSGS 2262
Query: 202 CESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGS 261
H G S +E + RH R + A+SSR G A G
Sbjct: 2263 ASRNHHG-SAQEQSRDGSRHPRSHHEDRAGHGHSAESSR-------QSGTHHAENSSGGQ 2314
Query: 262 GSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRE 321
+++ ++++ Q DS + +S+ R G +GS S S
Sbjct: 2315 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG-HRGSSGSQASDSEG 2373
Query: 322 LNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG----FQSPCLECAEVKKSSLV 377
+ + + S ++ + P + E+ S GR R +Q E +E
Sbjct: 2374 HSEDSDTQSVSAHGQAGPHQQSHQ-ESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
Query: 378 PST-ARSSPMKGCSRSSSYASTRSS------SHSSRSPNPRASPRYTQ-------SRSTS 423
ST R +R SS ST H S R Y Q S S
Sbjct: 2433 TSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHH 2492
Query: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRE---- 479
S S RS + SG RS ++ +S SR+S SR + S DS
Sbjct: 2493 SHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEAS-SRADSSGHSQVGQ 2551
Query: 480 -RERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYS 538
+ R R++ + DS H E S SGS S +
Sbjct: 2552 GQSEGPRTSRNWGSSFSQDSDSQGHSE----------------DSERWSGSASRNHHGSA 2595
Query: 539 SSSSRSASRSYSRSRSRSRS---RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595
R SR + RS R+ +R S + +++ S G + S ++RS + R
Sbjct: 2596 QEQLRDGSR-HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERH 2654
Query: 596 QSRSYSSADS 605
S SADS
Sbjct: 2655 GSHHQQSADS 2664
Score = 73.2 bits (178), Expect = 7e-13
Identities = 116/529 (21%), Positives = 195/529 (36%), Gaps = 28/529 (5%)
Query: 91 GHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSK 150
GH + + + S+RG+ ++ S P + + R+ S +
Sbjct: 439 GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHE 498
Query: 151 KRRHSSSSPKSKRRDE--KRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRG 208
+ R SS S+ + + H SR + SH H + +RS S S S S+ R
Sbjct: 499 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH---HEQSVNRSGHSGSHHSHTTSQGRS 555
Query: 209 RSPEEGQKSRRRHSRRC-SKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADL 267
+ GQ R SR+ ++ D SR Q S+R G G
Sbjct: 556 DA-SHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQAD---SSRHSQVGQG----- 606
Query: 268 FTKTASPLTT-SRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGN 326
+++ P T+ ++G S DS + S S + S + SR + SR S +
Sbjct: 607 --QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHH 664
Query: 327 TSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPM 386
+G+ + S + G + +S G+ + + E S +A SS
Sbjct: 665 EDRAGHGHSADSSRKSGT--RHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRH 722
Query: 387 KGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPS 446
G + ++ R S H S + +A+ S + ++ S + +S + S
Sbjct: 723 SGTGHGQASSAVRDSGHRGSSGS-QATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARD 781
Query: 447 RSS-RSRRSPSYS-RYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHL 504
RS RSRRS S+ + S ++ + + R+ + + + +D +
Sbjct: 782 RSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI 841
Query: 505 EARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR---- 560
+S R R ++ S SG S S +S ASR S SRS SR+ R
Sbjct: 842 RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQ 901
Query: 561 -RSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608
R +R S S + S SR + +S SR S+ S S
Sbjct: 902 SRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDS 950
Score = 72.0 bits (175), Expect = 1e-12
Identities = 122/596 (20%), Positives = 207/596 (34%), Gaps = 93/596 (15%)
Query: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
R+ G S+SH + ++ +R ++ +R ++ SS + S H+
Sbjct: 1327 RQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS----------RHSGIGHR 1376
Query: 144 RRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSH-----RHRHHRCPSRSQSSESR 198
+ S + H SS S+ + + H + S ++ +H + H+ +R QS ES
Sbjct: 1377 QASSAVRDSGHRGSSG-SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESS 1435
Query: 199 PSS------------CESRHRGRSPEEG--QKSRRRHSRRCSK-TLCKDSPEAQSSRPPS 243
S ES H +P G Q SR +R S+ + +D + P S
Sbjct: 1436 GRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGS 1495
Query: 244 -----------QPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTS 292
Q + G+ T +D + P + SR E SG+ +
Sbjct: 1496 SRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555
Query: 293 SP------PSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAML 346
PST+ S+R +G +G + R+ +S + + S + +
Sbjct: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615
Query: 347 ENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSR 406
N ++R + G ++P + ++R S + SS + S +
Sbjct: 1616 RNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS 1675
Query: 407 SPNPRASPRYTQSRSTSSEKRSYSRSPS---------------------YSSKS------ 439
SP R R+ QS +S++ + R S +S +S
Sbjct: 1676 SPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVS 1735
Query: 440 --GKRSPPSRS----------SRSRRSPSYS-RYSPSRERDPKYSEKDSQQRERERARRR 486
G+ P +S RS RS S+ + S + + + R+R+R
Sbjct: 1736 AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795
Query: 487 RRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS 546
+ S ++ + +S R +Y S SSG S S +S S
Sbjct: 1796 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVS 1855
Query: 547 RSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
R S SRS SR +TR S S GSR S SR + SS
Sbjct: 1856 RGQSGSRSVSR-----QTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSS 1906
Score = 71.2 bits (173), Expect = 3e-12
Identities = 127/539 (23%), Positives = 195/539 (36%), Gaps = 60/539 (11%)
Query: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
GHS SH T +S G + ++R+ R S S + +
Sbjct: 2486 GHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG 2545
Query: 148 FSKKRRHSSSSPKSKRR---------DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198
S+ + S P++ R D + H + S + R+ H + +
Sbjct: 2546 HSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2605
Query: 199 PSSCESRH--RGRSPEEGQKSRRRHSRRCSKTLCKDSPE-AQSS---RPPSQPLQMLGYL 252
P S + G S + ++S RH++ S S E A+SS R S Q
Sbjct: 2606 PRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2665
Query: 253 SARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSP 312
G+ G G A+ + RG S S N+ S S T S + GQ GS
Sbjct: 2666 RHSGI--GHGQASSAVRDSGH-----RGYSGSQASDNEGHSEDS-DTQSVSAHGQA-GSH 2716
Query: 313 SGGLSKSRELNSGNTSDSGNSFT--TSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAE 370
+S SG TS SF S+ + + P++RGR+ + + +
Sbjct: 2717 QQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ-AQDSSR 2775
Query: 371 VKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYS 430
S T R P Y S S S + S +Q RS +S +S S
Sbjct: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH-SHTTSQGRSDASRGQSGS 2834
Query: 431 RSPSYSSKSGKRSPP-SRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
RS S ++++ ++S SR S SR + + SR + Q + E +RR RR
Sbjct: 2835 RSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRH-------SQAVQGQSEGSRRSRRQ 2887
Query: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSY 549
S + + DS H E S SGS S + R SR +
Sbjct: 2888 GSSV-SQDSDSEGHSE----------------DSERWSGSASRNHHGSAQEQLRDGSR-H 2929
Query: 550 SRSRSRSRS---RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADS 605
RS R+ +R S + +++ S G + S ++RS + R S SADS
Sbjct: 2930 PRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988
Score = 70.9 bits (172), Expect = 3e-12
Identities = 120/525 (22%), Positives = 204/525 (38%), Gaps = 53/525 (10%)
Query: 111 KKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHK 170
++ +S + R S+ ++ + SS+ + R H SS +R + H
Sbjct: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS---RRGRQGSHY 3450
Query: 171 KQSRSRPRKSHRHRHHRCP------SRSQSSESRPSSCESRHRGRSPEEGQKSRRRH--- 221
+QS R S H H SR QS SR +S ++R+ +S + + S H
Sbjct: 3451 EQSVDRSGHSGSHHSHTTSQGRSDASRGQSG-SRSASRQTRNDEQSGDGSRHSWSHHHEA 3509
Query: 222 SRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGR 281
S + + S + QS+ P + Q S G + D + S RG
Sbjct: 3510 STQADSSRHSQSGQGQSAGPRTSRNQGS---SVSQDSDSQGHSEDSERWSGSASRNHRGS 3566
Query: 282 SQEYDSGNDTSSPPSTQTSSARSRGQE-KGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQ 340
+QE D S P++ G + S G + + G + S +S+ +
Sbjct: 3567 AQE--QSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGE 3624
Query: 341 NKGAMLENLSPTSRGRE-SRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTR 399
G+ + + +SR G S + + + SS +++S +G S S S
Sbjct: 3625 RHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSS----GSQASDSEGHSEDSDTQSV- 3679
Query: 400 SSSHSSRSPNPRASPRYTQSRSTSSEKRS---------YSRSPSYSSKSGKRSPPSRSSR 450
S+H P+ ++ T+ RS RS + +S S ++G + + SR
Sbjct: 3680 -SAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSR 3738
Query: 451 SRRSPSYSRYSPSRE-----RDPKYSEKDSQQ-----RERERARRRRRSYSPMRKRRRDS 500
++ SR+S S+E R S + +Q + +R+ +S + R
Sbjct: 3739 HEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSD 3798
Query: 501 PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR 560
SH ++ +++R+ S GS S S + +S+ +SR + S R
Sbjct: 3799 ASHGQSGSRSASRETR----NEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSR 3854
Query: 561 RSRTRTSS-SSSSRSPSPGSRSRSRSRSRSRSR---SRSQSRSYS 601
RSR + SS S S S + S RS S SR+ SR QSR S
Sbjct: 3855 RSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGS 3899
Score = 65.5 bits (158), Expect = 1e-10
Identities = 132/608 (21%), Positives = 219/608 (36%), Gaps = 136/608 (22%)
Query: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRD 165
++G+ K + T KR SSS +KK++K R + K +SS K+K +
Sbjct: 137 NKGRSKSPRETGGKRHESSS------EKKERKGYSPTHREEEYGKNHHNSSKKEKNKTEN 190
Query: 166 EKRHKKQSRSRPRKSHRH------------------------------------------ 183
+ + R R +
Sbjct: 191 TRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSL 250
Query: 184 -RHHRCPSRSQSSESRPSS--CESRHRGRS--PEEGQKSRRRHSRRCSKTLCKDSPEAQS 238
++ RS+SS+ + SS SRH S P + ++R+R R S+ + S
Sbjct: 251 LEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDS 310
Query: 239 SRPPSQPLQMLGYLSARGVITGS-------------GSAADLFTK--TASPLTTSRGRS- 282
R + + GS G +AD + T T+SRG++
Sbjct: 311 ERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTA 370
Query: 283 -----------QEYDSGNDTSSPPSTQTSSARSRGQEKGSPSG--GLSKSRELNSGNTSD 329
+ + SG+ S+ S +++ R + S G G S S+ +S S+
Sbjct: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSE 430
Query: 330 SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
+ ++ + S G ++ ++RGR E + SSL + P
Sbjct: 431 NSDTQSVSGHGKAGLRQQSHQESTRGRSG--------ERSGRSGSSLYQVSTHEQPDSAH 482
Query: 390 SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSS 449
R+ + R SH ++ R + S S E + R SS+ G++ S
Sbjct: 483 GRTGTSTGGRQGSHHEQA-------RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
Query: 450 --RSRRSPSYSRYSPSRER-DPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEA 506
RS S S+ ++ S+ R D + + S+ R+ R S R S H +
Sbjct: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQ---TRNEEQSGDGTRHSGSRHHEAS 592
Query: 507 RRITSARKRPI-------PYYRPSPSSSGSLSSTSSWYSSSSSR---SASRSY-----SR 551
+ S+R + P + SS S S S +S S R SASR++ +
Sbjct: 593 SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQ 652
Query: 552 SRSRSR-----------------SRRRSRTR-TSSSSSSRSPSPGSRSRSRSRSRSRSRS 593
SR SR S R+S TR T +SSS ++ S ++RS + R SR
Sbjct: 653 SRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRH 712
Query: 594 RSQSRSYS 601
+ QS S
Sbjct: 713 QLQSADSS 720
Score = 65.5 bits (158), Expect = 1e-10
Identities = 118/530 (22%), Positives = 188/530 (35%), Gaps = 59/530 (11%)
Query: 90 RGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFS 149
+G S S D D S+G + + R S S S + + ++S + S
Sbjct: 1914 QGSSVSQDSD------SQGHSEDSE------RWSGSASRNHLGSAWEQSRDGSRHPGSHH 1961
Query: 150 KKRRHSSSSPKSKRRDEKRH-KKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRG 208
+ R S S R+ RH + SR + SH R S S+ SRH G
Sbjct: 1962 EDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSG 2021
Query: 209 RSPEEGQKSRRRHSRR-CSKTLCKDSP--------EAQSSRPPSQPLQMLGYLSARGVIT 259
+ + R R S + DS ++ S++ + P Q SARG
Sbjct: 2022 IGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSG 2081
Query: 260 GSGSAADLF------------TKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQ 307
S + F T S +T + YD D+S ++Q RG
Sbjct: 2082 ESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGH 2141
Query: 308 EKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLE 367
S G +E + + SG+ + ++ Q + S SRG+ S
Sbjct: 2142 PGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGR-------SDASRGQSGSRSAS---- 2190
Query: 368 CAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKR 427
+K+ + S G + + SS HS + PR ++ R +S +
Sbjct: 2191 ----RKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQD 2246
Query: 428 SYSRSPSYSS--KSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARR 485
S S S S +SG S S +S SR+ S D + E +R+
Sbjct: 2247 SDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED-----RAGHGHSAESSRQ 2301
Query: 486 RRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA 545
++ + + SH +AR +SA +R +++ S SS SS+ S
Sbjct: 2302 SGTHHAENSSGGQAASSHEQAR--SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 2359
Query: 546 SRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595
R S S++ + T S S+ P +S S +R RS RS
Sbjct: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES-TRGRSAGRS 2408
Score = 64.3 bits (155), Expect = 3e-10
Identities = 117/547 (21%), Positives = 200/547 (36%), Gaps = 60/547 (10%)
Query: 114 KSTRKKRRRSSSYSPSPVKKKKKKSS--KKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKK 171
+STRK+ S + K +K S KH+ + K S +R + K +K
Sbjct: 87 ESTRKENLPISGH-------KHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKG 139
Query: 172 QSRSRPRKSHRHRHHRCPSRSQSSESRPSSCE----SRHRGRSPEEGQKSRRRHSRRCSK 227
+S+S PR++ RH + + P+ E H S +E K+ K
Sbjct: 140 RSKS-PRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRK 198
Query: 228 TLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS--------- 278
L + E + + + G ++ + + +G + A T S
Sbjct: 199 RLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYE 258
Query: 279 RGRSQEYDSGN--------DTSSPPSTQTSSARSRGQ--EKGSPSGGLSKSRELNSGNTS 328
R RS + S + +TS P ++ + + RG + S G S+ E +SG+ S
Sbjct: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSAS 318
Query: 329 DS--GNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPST---ARS 383
+ G+++ S ++ + S G + + AE S+ ARS
Sbjct: 319 RNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARS 378
Query: 384 SP--MKGCSRSSSYASTRSSS----HSSRSPNPRASPRYTQSRSTSSE---KRSYSRSPS 434
SP G S S+R S+ +S + + R + S+++ SE + S ++S S
Sbjct: 379 SPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVS 438
Query: 435 YSSKSGKRSPPSRSSRSRRS--------PSYSRYSPSRERDPKYSEKDSQQRERERARRR 486
K+G R + S RS S + S + D + + R+ +
Sbjct: 439 GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHE 498
Query: 487 RRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS 546
+ S ++ + +S R ++ S + SG S S +S AS
Sbjct: 499 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDAS 558
Query: 547 RSYSRSRSRSRSRRRSR-----TRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYS 601
S SRS SR R TR S S + S SR + +S SR+
Sbjct: 559 HGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQG 618
Query: 602 SADSYSS 608
S+ S S
Sbjct: 619 SSVSQDS 625
Score = 64.3 bits (155), Expect = 3e-10
Identities = 120/558 (21%), Positives = 197/558 (35%), Gaps = 43/558 (7%)
Query: 75 NSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKK--KKSTRKKRRRSSSYSPSPVK 132
+S R + + GHS D G ++ ++S R + +S +S S +
Sbjct: 3005 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 3064
Query: 133 KKK--KKSSKKHKRRRSFSKKR---RHSSSSPKSKRRDEKRHKKQSRSRPRKSH--RHRH 185
+ ++S H ++ R RH + S+ + + R P S R +
Sbjct: 3065 QVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGY 3124
Query: 186 HRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245
H S S S + +GRS +S R + R ++ E QS
Sbjct: 3125 HHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN------EEQSGDSSRHS 3178
Query: 246 LQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSR 305
+ S I+ A ++ S + +G S DS ++ S S + S + SR
Sbjct: 3179 VSRHHEASTHADISRHSQAVQGQSE-GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASR 3237
Query: 306 GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPC 365
SR S + +G+ + + G + TS G ++
Sbjct: 3238 NHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGT---RHAETSSGGQAASSHEQA 3294
Query: 366 LECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSE 425
+ S +A SS G R + ++ R S H S + +AS S + ++
Sbjct: 3295 RSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGS-QASDSEGHSEESDTQ 3353
Query: 426 KRSYSRSPSYSSKSGKRSPPSRSS-RSRRSPSYSRYSPSRERDPKYSEKDSQQRERERAR 484
S +S + S RS RS RS S+ + E+ + + R R
Sbjct: 3354 SVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQS-----ESAHGRTRTSTG 3408
Query: 485 RRRRSYSPMRKRRRDSPSH---------LEARRITSARKRPIPYYRPSPSSSGSLSSTSS 535
RR+ S+ ++ RDS H + +S R R +Y S SG S S
Sbjct: 3409 RRQGSH---HEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHS 3465
Query: 536 WYSSSSSRSASRSYSRSRSRSRSRRRSR-----TRTSSSSSSRSPSPGSRSRSRSRSRSR 590
+S ASR S SRS SR R +R S S + + SR + +
Sbjct: 3466 HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQ 3525
Query: 591 SRSRSQSRSYSSADSYSS 608
S SR+ S+ S S
Sbjct: 3526 SAGPRTSRNQGSSVSQDS 3543
Score = 62.8 bits (151), Expect = 9e-10
Identities = 108/481 (22%), Positives = 163/481 (33%), Gaps = 40/481 (8%)
Query: 134 KKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
K+ + S +H + S R+ + RS SH H H RS
Sbjct: 2444 KQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSH-HSHTTSQGRSD 2502
Query: 194 SSESRPSSCESRHRGRSPEE-GQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYL 252
+S S + + R+ E+ G SR SR SSR S +G
Sbjct: 2503 ASHGHSGSRSASRQTRNDEQSGDGSRHSGSRH----------HEASSRADSSGHSQVGQG 2552
Query: 253 SARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSP 312
+ G T + + G S DS + S S + S + SR +
Sbjct: 2553 QSEGPRT----------------SRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQ 2596
Query: 313 SGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVK 372
SR S +G+ + S + G + TS G ++ A +
Sbjct: 2597 EQLRDGSRHPRSHQEDRAGHGHSADSSRQSGT---RHTQTSSGGQAASSHEQARSSAGER 2653
Query: 373 KSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRS 432
S +A SS G + ++ R S H S + +AS S + ++ S
Sbjct: 2654 HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGS-QASDNEGHSEDSDTQSVSAHGQ 2712
Query: 433 PSYSSKSGKRSPPSRSSR-SRRSPSYS-RYSPSRERDPKYSEKDSQQRERERARRRRRSY 490
+S + S RS S S S+ + S + + + R R+ +R +
Sbjct: 2713 AGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQD 2772
Query: 491 SPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYS 550
S +D + +S R ++ S SSG S S +S ASR S
Sbjct: 2773 SSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQS 2832
Query: 551 RSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
SRS SR+ TR S S GSR S SR SQ+ S S S R
Sbjct: 2833 GSRSASRT-----TRNEEQSGDGSRHSGSRHHEASTHADISR-HSQAVQGQSEGSRRSRR 2886
Query: 611 R 611
+
Sbjct: 2887 Q 2887
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/226 (20%), Positives = 85/226 (37%), Gaps = 10/226 (4%)
Query: 393 SSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR 452
S + + S H N + + + R +S E+R+ + SKS + + R S
Sbjct: 97 SGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSS 156
Query: 453 RSPSYSRYSPSRERDPKY-------SEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLE 505
YSP+ R+ +Y S+K+ + E R R+ S + + D+ +
Sbjct: 157 EKKERKGYSPT-HREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVY 215
Query: 506 ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTR 565
T + + + ++ ++ ++ S ++ Y RSRS R
Sbjct: 216 DYENTGRMTQ--KWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNR 273
Query: 566 TSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
+ ++S+ P SR+R R SR S+ S S S R
Sbjct: 274 SRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASR 319
Score = 38.5 bits (88), Expect = 0.018
Identities = 50/230 (21%), Positives = 79/230 (34%), Gaps = 43/230 (18%)
Query: 91 GHSASHDKDLTPP---PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRS 147
GHS SH T +S G+ + ++R+ R S S + S +H +
Sbjct: 3782 GHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGS------RHSGSRHHEAST 3835
Query: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHR 207
+ RHS S + + +R ++Q S + S + + SE R S H
Sbjct: 3836 QADSSRHSQSG-QGESAGSRRSRRQGSSVSQDSDSEAY------PEDSERRSESASRNHH 3888
Query: 208 GRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADL 267
G S E+ + R S +S S P+Q +D
Sbjct: 3889 GSSREQSRDGSRHPG---------SSHRDTASHVQSSPVQ-----------------SDS 3922
Query: 268 FTKTASPLTTSRGRSQEYDSG-NDTSSPPSTQTSSARSRGQEKGSPSGGL 316
T +S + Y SG SP S+ + +S G E+ GL
Sbjct: 3923 STAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGL 3972
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 89.0 bits (219), Expect = 1e-17
Identities = 138/548 (25%), Positives = 183/548 (33%), Gaps = 22/548 (4%)
Query: 80 DKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSS 139
D + E ++ S S D SS S SS S S SS
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 140 KKHKRRRSF-SKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198
S S SS S S D S S S S SS+S
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 199 PSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVI 258
SS S S + S + DS + S S ++
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 259 TGSGSA--ADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTS---------------S 301
S S+ +D +S + S S DS N + S S+ +S S
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 302 ARSRGQEKGSPSGGLSKSRELN-SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG 360
+ S S S S S + N S N+SDS +S +S + + N S +S S
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS--SNSSDSSDSSNSSD 922
Query: 361 FQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSR 420
S ++ SS +++ SS S SS +++ SS+SS S + +S S
Sbjct: 923 -SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 421 STSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER 480
S+ S S S S SS S S S SS S S + S S S + DS
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 481 ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSS 540
S S S + S+ S SS S +S+ S SS
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 541 SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSY 600
SS S+ S S S S S + SS SS S + S S S S S S S
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 601 SSADSYSS 608
SS S SS
Sbjct: 1162 SSDSSDSS 1169
Score = 84.7 bits (208), Expect = 2e-16
Identities = 125/516 (24%), Positives = 182/516 (35%), Gaps = 63/516 (12%)
Query: 94 ASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRR 153
+S+ D + S S R SS S S SS S +
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 154 HSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS--CESRHRGRSP 211
SS+ + + S S S SS+S SS +S S
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 212 EEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKT 271
+ S +S S + DS ++ +S + S ++D +
Sbjct: 955 DSSNSSDSSNSSDSSDSNSSDSSDSSNS-------------------SDSSDSSDSSDSS 995
Query: 272 ASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSG 331
S +++ S + +D+S+ + SS S + S S +S ++SDS
Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055
Query: 332 NSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSR 391
NS +S + S +S +S S + +E SS +++ SS S
Sbjct: 1056 NSSDSSDSSDS-------SDSSDSSDS----SDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104
Query: 392 SSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRS 451
SS + + SS SS S N S S S+ S S S + S SS S + S S SS S
Sbjct: 1105 SSDSSDSSDSSDSSDSSNSSDS-----SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Query: 452 RRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITS 511
S S S S + + DS S S DS ++
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSD----------SSDSSDSSDSSDSSDSSDS----- 1204
Query: 512 ARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSS 571
S SS S SS SS S SS S S + S S S S + SS SS
Sbjct: 1205 -----------SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253
Query: 572 SRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYS 607
S S S S S S S+S+S + + + S +DS S
Sbjct: 1254 DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS 1289
Score = 79.7 bits (195), Expect = 7e-15
Identities = 131/504 (25%), Positives = 191/504 (37%), Gaps = 49/504 (9%)
Query: 149 SKKRRHSSSSPKSK--RRDEKRHKKQSRSRPRKSHR-----HRHHRCPSRSQSSESRPSS 201
SK +S+ P+ +R E K R R +R H S+ + E + S
Sbjct: 323 SKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPS 382
Query: 202 CESRHRGRSP---EEGQKSRRRHSRRCSKTLCKDSPEAQSSRPP---SQPLQMLGYLSAR 255
+R+ + EG++ + +H K K E + P S+P +G+ +
Sbjct: 383 SGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSN-- 440
Query: 256 GVITGSGSAADLFTKTASPLTTSRG---RSQEYDSGNDTSSPPSTQTSSAR--------- 303
TGS S +D + + +G S + +GND ++ S SS+R
Sbjct: 441 ---TGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE 497
Query: 304 SRGQEKGSPSGGL--------SKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTS-R 354
S+ GS S G S + +S ++GN S KG + S +S
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 355 GRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASP 414
S S + ++ SS S+ S S SS +++ SS SS S + S
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Query: 415 RYTQSRSTSSEKRSYS-----RSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPK 469
+ S+S SS+ S S +S S S S S S SS S S + S S S +
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 470 YSEKD----SQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPS 525
S D S + + S DS ++ S+ S S
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 526 SSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSS-SRSPSPGSRSRSR 584
S+ S SS SS S+SS S S S S S S S + SS+SS S S S S
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 585 SRSRSRSRSRSQSRSYSSADSYSS 608
S S S S S S S+DS SS
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSS 821
Score = 79.7 bits (195), Expect = 7e-15
Identities = 94/334 (28%), Positives = 138/334 (41%), Gaps = 5/334 (1%)
Query: 277 TSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS-FT 335
+ +G+S DS + SS S + S+ S + S S S S + +S ++SDS +S +
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD--SDSSDSDSSDSSDSDSSDSS 599
Query: 336 TSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSY 395
SS + + + S +S +S+ S + S S + SS S SS
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Query: 396 ASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSP 455
+++ +SS SS S + +S + S S++S S S S SS+S S S S S S
Sbjct: 660 SNSSNSSDSSDSSD--SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717
Query: 456 SYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKR 515
S + S + DS + S S S + S+
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Query: 516 PIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSP 575
S SS S S+ S SS SS S+ S S S S S S + SS SS S
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837
Query: 576 SPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSST 609
S S S S S S S ++S S +S+DS S+
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Score = 79.7 bits (195), Expect = 7e-15
Identities = 99/346 (28%), Positives = 147/346 (42%), Gaps = 20/346 (5%)
Query: 270 KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEK----GSPSGGLSKSRELNSG 325
K+ S + S S DS + + S S SS+ S + S S S +S
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 326 NTSDSGNSFTTS-SPQNKGAMLENLSPTS-RGRESRGFQSPCLECAEVKKSSLVPSTARS 383
++SDS +S +S S +K ++ S +S +S S + ++ SS +++ S
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 384 SPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRS 443
S S SS +S+ SS+SS S + +S S S+ S S S S S S S
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSD--SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723
Query: 444 PPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSH 503
S SS S S S S S + + DS + + S S DS +
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 504 LEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSR 563
++ ++ S SS S +S+ S SS SS S+ S S S + S S S
Sbjct: 783 SDSNDSSN-----------SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Query: 564 TRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSST 609
+ SS+SS S S S S S S +RS S + S S S+DS +S+
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Score = 75.9 bits (185), Expect = 1e-13
Identities = 113/454 (24%), Positives = 163/454 (35%), Gaps = 45/454 (9%)
Query: 191 RSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLG 250
++ SE + + + E+ QK R S+R + K+S + + +++ G
Sbjct: 321 KTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKG 380
Query: 251 YLSA--------------------RGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGND 290
S G+I G G+ KT + G Q+ + GN
Sbjct: 381 PSSGNRNITKEVGKGNEGKEDKGQHGMILGKGN-----VKTQGEVVNIEGPGQKSEPGNK 435
Query: 291 TSSPPSTQTSSARSRG------QEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGA 344
S S + S G +K + S E N + ++S + +SS +
Sbjct: 436 VGH--SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASY 493
Query: 345 MLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTA--------RSSPMKGCSRSSSYA 396
+ G +S+G + + +S +S KG S SS
Sbjct: 494 NSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553
Query: 397 STRS--SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRS 454
S+ S SS SS S + +S + S S SS+ S S S SS S S S SS S S
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 455 PSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARK 514
S S S+ D SE DS + + S S S S + S+
Sbjct: 614 SDSSDSSDSKS-DSSKSESDSSDSDSKSDSSDSNS-SDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 515 RPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRS 574
S SS S S+ S SS+SS S+ S S S S S + +S S SS S
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 575 PSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608
S S S S S S S SS S SS
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765
Score = 54.3 bits (129), Expect = 3e-07
Identities = 80/379 (21%), Positives = 121/379 (31%), Gaps = 10/379 (2%)
Query: 105 SSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRR 164
SS S SS S S SS S +SS S S
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 165 DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRR 224
+ S S S SS+S SS S S S
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 225 CSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQE 284
+ DS ++ +S S + S S+ + +S + S S
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 285 YDSGN--------DTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTT 336
DS + D+S ++ SS S + S S S ++SDS +S +
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162
Query: 337 S-SPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSY 395
S S + + + S S S + ++ SS ++ SS S SS
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222
Query: 396 ASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSP 455
+ + SS S+ S + S + S ++S S S S S + + S+S +
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNG 1282
Query: 456 SYSRYSPSRERDPKYSEKD 474
S S S S D +S D
Sbjct: 1283 SDSD-SDSEGSDSNHSTSD 1300
Score = 33.9 bits (76), Expect = 0.45
Identities = 72/330 (21%), Positives = 110/330 (33%), Gaps = 37/330 (11%)
Query: 281 RSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNS-GNTSDSGNSFTTSSP 339
+S+E +G + + + +E ++K E ++ G + D G S
Sbjct: 324 KSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSS 383
Query: 340 QNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTR 399
N+ E + + G+E +G L VK V + +++T
Sbjct: 384 GNRNITKE-VGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTG 442
Query: 400 SSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSR 459
S S+S + + Q +S S + S +S SR SY+
Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDES-------NGNDDANSESDNNSSSRGDASYN- 494
Query: 460 YSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPY 519
S E + DS+ E + DS S + S
Sbjct: 495 ---SDESKDNGNGSDSKGAEDD-----------------DSDSTSDTNNSDSNGNGNNGN 534
Query: 520 YRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGS 579
S SG S SS SS S ++S S S S S ++SSS S S S
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD-------SNSSSDSDSSDSDS 587
Query: 580 RSRSRSRSRSRSRSRSQSRSYSSADSYSST 609
S S S S S S S S+DS S+
Sbjct: 588 SDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 85.9 bits (211), Expect = 1e-16
Identities = 93/299 (31%), Positives = 128/299 (42%), Gaps = 36/299 (12%)
Query: 328 SDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMK 387
SD G + +SP S R ES + E K + S + K
Sbjct: 1759 SDVGRDRSAASPVVS-------SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDK 1811
Query: 388 GCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSR 447
G +S RS S S+S ++ R ++SRS + ++ S S+S ++S RS R
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 448 SSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERAR------------------RRRRS 489
S RS S R S S+E+ + + S+ RER+R R RR RS
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS 1931
Query: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRP-SPSSSGSLSSTSSWYSSSSSRSASRS 548
++P R+RR S + I+ +R+ P R +PS S S S SR+ SR
Sbjct: 1932 HTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR- 1990
Query: 549 YSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR------SRSRSRSQSRSYS 601
RSR+ SR RRRSR+ S S SP RSR+ R R R RSRS R S
Sbjct: 1991 --RSRTPSR-RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 77.4 bits (189), Expect = 4e-14
Identities = 104/343 (30%), Positives = 144/343 (41%), Gaps = 40/343 (11%)
Query: 290 DTSSP----PSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM 345
DT P S QT +A +E SGG + DSG S N+ +
Sbjct: 1678 DTEEPLPVKESDQTLAALLSPKES---SGGEKEVPPPPKETLPDSGFSANIEDI-NEADL 1733
Query: 346 LENLSPTSRGRESR---GFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSS-------- 394
+ L P R + G + P L ++V + S SS + S SSS
Sbjct: 1734 VRPLLPKDMERLTSLRAGIEGPLL-ASDVGRDRSAASPVVSSMPERASESSSEEKDDYEI 1792
Query: 395 YASTRSSSHSSRSPNPR----------ASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSP 444
+ + + S+ R +S R RS SSE +S R+ S++ KRS
Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852
Query: 445 PSRSSRSR---RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSP 501
S+S RS+ RS S R SR R + + +R+R+ + R S R+R+R
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR---SKSRERKRKRS 1909
Query: 502 SHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRS-RR 560
S + R+ AR R S + S S S S S S SR RSR+ R
Sbjct: 1910 SSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 561 RSRT--RTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYS 601
RSRT R S + S RS +P RSR+ SR R RSRS + RS+S
Sbjct: 1970 RSRTPSRRSRTPSRRSRTPSRRSRTPSR-RRRSRSVVRRRSFS 2011
Score = 77.0 bits (188), Expect = 5e-14
Identities = 84/239 (35%), Positives = 108/239 (45%), Gaps = 46/239 (19%)
Query: 399 RSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRS---- 454
R SS SRS ++S +SR +SE RS +R S SKS + SRS RSRR
Sbjct: 1818 RDSSLRSRSKRSKSSEH--KSRKRTSESRSRARKRSSKSKSHRSQTRSRS-RSRRRRRSS 1874
Query: 455 ----PSYSRYSPSRERDPKYSEKDSQQRERERAR------------------RRRRSYSP 492
S R S S+E+ + + S+ RER+R R RR RS++P
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP 1934
Query: 493 MRKRRRDSPSHLEARRITSARKRPIPYYRP-SPSSSGSLSSTSSWYSSSSSRSASRSYSR 551
R+RR S + I+ +R+ P R +PS S S S SR+ SR R
Sbjct: 1935 SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR---R 1991
Query: 552 SRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRS------------RSRSRSRSRSRSQSR 598
SR+ SR RRRSR+ S S SP RSR+ R RSRS R RS R
Sbjct: 1992 SRTPSR-RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 65.5 bits (158), Expect = 1e-10
Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 13/168 (7%)
Query: 443 SPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPS 502
S P R+S S + +D K ++ R++ ++R S R +R S
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833
Query: 503 HLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRS 562
H +R + +R R R S S S S +RS SRS R RS SRSR +S
Sbjct: 1834 HKSRKRTSESRSRA----RKRSSKSKS--------HRSQTRSRSRSRRRRRS-SRSRSKS 1880
Query: 563 RTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
R R S S R SP RS+SR R R RS SR ++ + S R
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Score = 65.5 bits (158), Expect = 1e-10
Identities = 70/244 (28%), Positives = 99/244 (40%), Gaps = 10/244 (4%)
Query: 277 TSRGRSQEYDSGNDTSSPPS-TQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFT 335
+ R +S E+ S TS S + S++S+ + S S+ R +S + S S +
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRS 1885
Query: 336 TS------SPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
S SP+++ E S R++R + S PS R S G
Sbjct: 1886 VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGR 1945
Query: 390 SRSSSYA-STRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRS 448
RS S + S RS + S RS P R RS + +RS R+PS S++ R SRS
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS--RTPSRRSRTPSRRRRSRS 2003
Query: 449 SRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARR 508
RRS S S R R P R+R+R R SP R D LE +
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAK 2063
Query: 509 ITSA 512
+A
Sbjct: 2064 ANAA 2067
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/151 (32%), Positives = 71/151 (47%), Gaps = 4/151 (2%)
Query: 97 DKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKK--KKKSSKKHKRRRSFSKKRRH 154
+K+ S R + K+ KS+ K R+ +S S S +K+ K KS + R RS S++RR
Sbjct: 1813 EKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRR 1872
Query: 155 SSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPS-SCESRHRGRSPEE 213
SS S +SK R + K+ R R K R RS S ++R + SR R
Sbjct: 1873 SSRS-RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS 1931
Query: 214 GQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244
SRRR SR + ++ SR PS+
Sbjct: 1932 HTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962
Score = 63.9 bits (154), Expect = 4e-10
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 20/208 (9%)
Query: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRD 165
S+ K + K ++K+R SS S S K+ KSS+ R+R+ + R S KS
Sbjct: 1803 SKKNKNRDKGEKEKKRDSSLRSRS----KRSKSSEHKSRKRTSESRSRARKRSSKS---- 1854
Query: 166 EKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRC 225
K H+ Q+RSR R R R R SRS+S R S E R RSP+ KSR R +R
Sbjct: 1855 -KSHRSQTRSRSRSRRRRRSSR--SRSKSRGRRSVSKEKRK--RSPKHRSKSRERKRKRS 1909
Query: 226 SKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEY 285
S + + A+S P + R G + + SP SR S+
Sbjct: 1910 SSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSI-----SPSRRSRTPSRRS 1964
Query: 286 DSGNDTSSPPS--TQTSSARSRGQEKGS 311
+ + S PS ++T S RSR + S
Sbjct: 1965 RTPSRRSRTPSRRSRTPSRRSRTPSRRS 1992
Score = 63.5 bits (153), Expect = 5e-10
Identities = 55/186 (29%), Positives = 79/186 (42%), Gaps = 21/186 (11%)
Query: 73 GTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKS----------TRKKRRR 122
G +RD + R S + T SR +K+ KS +R +RRR
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 123 SSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHR 182
SS S S K + ++S K KR+R S K R S K KR + ++K R+R R R
Sbjct: 1872 RSSRSRS--KSRGRRSVSKEKRKR--SPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 183 HRHHRCPSRSQSSES----RPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQS 238
PSR + S S R S R R+P ++ R SR S+ + ++
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR---RSRTPSRR 1984
Query: 239 SRPPSQ 244
SR PS+
Sbjct: 1985 SRTPSR 1990
Score = 57.8 bits (138), Expect = 3e-08
Identities = 65/232 (28%), Positives = 100/232 (43%), Gaps = 21/232 (9%)
Query: 60 SEKLGQHLATEPLGTNSWERDKTCRELGATRGH-SASHDKDLTPPP---SSRGKKKKKKS 115
S K H + + S R ++ R +RG S S +K P SR +K+K+ S
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSS 1910
Query: 116 TRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRS 175
+R R+ + S +P ++ +S +RRRS S RR S S S+R + ++SR+
Sbjct: 1911 SRDNRKTVRARSRTP--SRRSRSHTPSRRRRSRSVGRRRSFSISPSRR--SRTPSRRSRT 1966
Query: 176 RPRKSHR-HRHHRCPSRSQSSESRPSSCESRHR-----------GRSPEEGQKSRRRHSR 223
R+S R R PSR + SR S SR R SP ++SR R
Sbjct: 1967 PSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRR 2026
Query: 224 RCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPL 275
R S++ + S R S P ++ A+ + +AA + K PL
Sbjct: 2027 RFSRSPIRRKRSRSSERGRS-PKRLTDLDKAQLLEIAKANAAAMCAKAGVPL 2077
Score = 54.3 bits (129), Expect = 3e-07
Identities = 87/332 (26%), Positives = 119/332 (35%), Gaps = 87/332 (26%)
Query: 131 VKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKK-----QSRSRPRK-SHRHR 184
VK +KS K R + +K+R SS +SKR HK +SRSR RK S + +
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK 1855
Query: 185 HHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244
HR +RS+S R R RS G++S + R K SP+ +S
Sbjct: 1856 SHRSQTRSRSRSRRRRRSS---RSRSKSRGRRSVSKEKR-------KRSPKHRSK----- 1900
Query: 245 PLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARS 304
SR R ++ S D + +T ARS
Sbjct: 1901 ---------------------------------SRERKRKRSSSRD-----NRKTVRARS 1922
Query: 305 RGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGR-ESRGFQS 363
R + S S S+ R S S ++SP+ R R SR ++
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRS----------------FSISPSRRSRTPSRRSRT 1966
Query: 364 PCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTS 423
P + S PS +P SR S S R S S + RS +
Sbjct: 1967 PSRRSRTPSRRSRTPSRRSRTP----SRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSP 455
+R +SRSP R SRSS RSP
Sbjct: 2023 PLRRRFSRSPI-------RRKRSRSSERGRSP 2047
Score = 52.8 bits (125), Expect = 9e-07
Identities = 54/174 (31%), Positives = 73/174 (41%), Gaps = 32/174 (18%)
Query: 450 RSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRI 509
RS SP S P R + EKD + E + + ++ +K + E +R
Sbjct: 1765 RSAASPVVSSM-PERASESSSEEKD----DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 510 TSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSS 569
+S R R S S SS + S S SRS +R RS RS+TR+ S
Sbjct: 1820 SSLRSR-------------SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSR 1866
Query: 570 SSSRSPSPGSRSRSRSR-------------SRSRSRSRSQSRSYSSADSYSSTR 610
S R S SRS+SR R RS+SR R + RS SS D+ + R
Sbjct: 1867 SRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRS-SSRDNRKTVR 1919
Score = 36.6 bits (83), Expect = 0.069
Identities = 32/116 (27%), Positives = 44/116 (37%), Gaps = 16/116 (13%)
Query: 107 RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDE 166
R K K+ +RK R S P + K SKKHK +H + K K+ E
Sbjct: 78 RYKPDLKEGSRKSR--CVSVQTDPTDEIPTKKSKKHK---------KHKNKKKKKKKEKE 126
Query: 167 KRHKKQSRSRPRKSHRHRHHRCPSRSQS-----SESRPSSCESRHRGRSPEEGQKS 217
K++K+Q K+ H S S SE + E R P E +S
Sbjct: 127 KKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAFGPSETNES 182
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 85.9 bits (211), Expect = 1e-16
Identities = 93/299 (31%), Positives = 128/299 (42%), Gaps = 36/299 (12%)
Query: 328 SDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMK 387
SD G + +SP S R ES + E K + S + K
Sbjct: 1759 SDVGRDRSAASPVVS-------SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDK 1811
Query: 388 GCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSR 447
G +S RS S S+S ++ R ++SRS + ++ S S+S ++S RS R
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 448 SSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERAR------------------RRRRS 489
S RS S R S S+E+ + + S+ RER+R R RR RS
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS 1931
Query: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRP-SPSSSGSLSSTSSWYSSSSSRSASRS 548
++P R+RR S + I+ +R+ P R +PS S S S SR+ SR
Sbjct: 1932 HTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR- 1990
Query: 549 YSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR------SRSRSRSQSRSYS 601
RSR+ SR RRRSR+ S S SP RSR+ R R R RSRS R S
Sbjct: 1991 --RSRTPSR-RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 77.4 bits (189), Expect = 4e-14
Identities = 104/343 (30%), Positives = 144/343 (41%), Gaps = 40/343 (11%)
Query: 290 DTSSP----PSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM 345
DT P S QT +A +E SGG + DSG S N+ +
Sbjct: 1678 DTEEPLPVKESDQTLAALLSPKES---SGGEKEVPPPPKETLPDSGFSANIEDI-NEADL 1733
Query: 346 LENLSPTSRGRESR---GFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSS-------- 394
+ L P R + G + P L ++V + S SS + S SSS
Sbjct: 1734 VRPLLPKDMERLTSLRAGIEGPLL-ASDVGRDRSAASPVVSSMPERASESSSEEKDDYEI 1792
Query: 395 YASTRSSSHSSRSPNPR----------ASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSP 444
+ + + S+ R +S R RS SSE +S R+ S++ KRS
Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSS 1852
Query: 445 PSRSSRSR---RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSP 501
S+S RS+ RS S R SR R + + +R+R+ + R S R+R+R
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHR---SKSRERKRKRS 1909
Query: 502 SHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRS-RR 560
S + R+ AR R S + S S S S S S SR RSR+ R
Sbjct: 1910 SSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 561 RSRT--RTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYS 601
RSRT R S + S RS +P RSR+ SR R RSRS + RS+S
Sbjct: 1970 RSRTPSRRSRTPSRRSRTPSRRSRTPSR-RRRSRSVVRRRSFS 2011
Score = 77.0 bits (188), Expect = 5e-14
Identities = 84/239 (35%), Positives = 108/239 (45%), Gaps = 46/239 (19%)
Query: 399 RSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRS---- 454
R SS SRS ++S +SR +SE RS +R S SKS + SRS RSRR
Sbjct: 1818 RDSSLRSRSKRSKSSEH--KSRKRTSESRSRARKRSSKSKSHRSQTRSRS-RSRRRRRSS 1874
Query: 455 ----PSYSRYSPSRERDPKYSEKDSQQRERERAR------------------RRRRSYSP 492
S R S S+E+ + + S+ RER+R R RR RS++P
Sbjct: 1875 RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP 1934
Query: 493 MRKRRRDSPSHLEARRITSARKRPIPYYRP-SPSSSGSLSSTSSWYSSSSSRSASRSYSR 551
R+RR S + I+ +R+ P R +PS S S S SR+ SR R
Sbjct: 1935 SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR---R 1991
Query: 552 SRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRS------------RSRSRSRSRSRSQSR 598
SR+ SR RRRSR+ S S SP RSR+ R RSRS R RS R
Sbjct: 1992 SRTPSR-RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 65.5 bits (158), Expect = 1e-10
Identities = 54/168 (32%), Positives = 73/168 (43%), Gaps = 13/168 (7%)
Query: 443 SPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPS 502
S P R+S S + +D K ++ R++ ++R S R +R S
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833
Query: 503 HLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRS 562
H +R + +R R R S S S S +RS SRS R RS SRSR +S
Sbjct: 1834 HKSRKRTSESRSRA----RKRSSKSKS--------HRSQTRSRSRSRRRRRS-SRSRSKS 1880
Query: 563 RTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
R R S S R SP RS+SR R R RS SR ++ + S R
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Score = 65.5 bits (158), Expect = 1e-10
Identities = 70/244 (28%), Positives = 99/244 (40%), Gaps = 10/244 (4%)
Query: 277 TSRGRSQEYDSGNDTSSPPS-TQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFT 335
+ R +S E+ S TS S + S++S+ + S S+ R +S + S S +
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRS 1885
Query: 336 TS------SPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
S SP+++ E S R++R + S PS R S G
Sbjct: 1886 VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGR 1945
Query: 390 SRSSSYA-STRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRS 448
RS S + S RS + S RS P R RS + +RS R+PS S++ R SRS
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS--RTPSRRSRTPSRRRRSRS 2003
Query: 449 SRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARR 508
RRS S S R R P R+R+R R SP R D LE +
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAK 2063
Query: 509 ITSA 512
+A
Sbjct: 2064 ANAA 2067
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/151 (32%), Positives = 71/151 (47%), Gaps = 4/151 (2%)
Query: 97 DKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKK--KKKSSKKHKRRRSFSKKRRH 154
+K+ S R + K+ KS+ K R+ +S S S +K+ K KS + R RS S++RR
Sbjct: 1813 EKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRR 1872
Query: 155 SSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPS-SCESRHRGRSPEE 213
SS S +SK R + K+ R R K R RS S ++R + SR R
Sbjct: 1873 SSRS-RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS 1931
Query: 214 GQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244
SRRR SR + ++ SR PS+
Sbjct: 1932 HTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962
Score = 63.9 bits (154), Expect = 4e-10
Identities = 65/208 (31%), Positives = 92/208 (44%), Gaps = 20/208 (9%)
Query: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRD 165
S+ K + K ++K+R SS S S K+ KSS+ R+R+ + R S KS
Sbjct: 1803 SKKNKNRDKGEKEKKRDSSLRSRS----KRSKSSEHKSRKRTSESRSRARKRSSKS---- 1854
Query: 166 EKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRC 225
K H+ Q+RSR R R R R SRS+S R S E R RSP+ KSR R +R
Sbjct: 1855 -KSHRSQTRSRSRSRRRRRSSR--SRSKSRGRRSVSKEKRK--RSPKHRSKSRERKRKRS 1909
Query: 226 SKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEY 285
S + + A+S P + R G + + SP SR S+
Sbjct: 1910 SSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSI-----SPSRRSRTPSRRS 1964
Query: 286 DSGNDTSSPPS--TQTSSARSRGQEKGS 311
+ + S PS ++T S RSR + S
Sbjct: 1965 RTPSRRSRTPSRRSRTPSRRSRTPSRRS 1992
Score = 63.5 bits (153), Expect = 5e-10
Identities = 55/186 (29%), Positives = 79/186 (42%), Gaps = 21/186 (11%)
Query: 73 GTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKS----------TRKKRRR 122
G +RD + R S + T SR +K+ KS +R +RRR
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871
Query: 123 SSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHR 182
SS S S K + ++S K KR+R S K R S K KR + ++K R+R R R
Sbjct: 1872 RSSRSRS--KSRGRRSVSKEKRKR--SPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 183 HRHHRCPSRSQSSES----RPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQS 238
PSR + S S R S R R+P ++ R SR S+ + ++
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR---RSRTPSRR 1984
Query: 239 SRPPSQ 244
SR PS+
Sbjct: 1985 SRTPSR 1990
Score = 57.8 bits (138), Expect = 3e-08
Identities = 65/232 (28%), Positives = 100/232 (43%), Gaps = 21/232 (9%)
Query: 60 SEKLGQHLATEPLGTNSWERDKTCRELGATRGH-SASHDKDLTPPP---SSRGKKKKKKS 115
S K H + + S R ++ R +RG S S +K P SR +K+K+ S
Sbjct: 1851 SSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSS 1910
Query: 116 TRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRS 175
+R R+ + S +P ++ +S +RRRS S RR S S S+R + ++SR+
Sbjct: 1911 SRDNRKTVRARSRTP--SRRSRSHTPSRRRRSRSVGRRRSFSISPSRR--SRTPSRRSRT 1966
Query: 176 RPRKSHR-HRHHRCPSRSQSSESRPSSCESRHR-----------GRSPEEGQKSRRRHSR 223
R+S R R PSR + SR S SR R SP ++SR R
Sbjct: 1967 PSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRR 2026
Query: 224 RCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPL 275
R S++ + S R S P ++ A+ + +AA + K PL
Sbjct: 2027 RFSRSPIRRKRSRSSERGRS-PKRLTDLDKAQLLEIAKANAAAMCAKAGVPL 2077
Score = 54.3 bits (129), Expect = 3e-07
Identities = 87/332 (26%), Positives = 119/332 (35%), Gaps = 87/332 (26%)
Query: 131 VKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKK-----QSRSRPRK-SHRHR 184
VK +KS K R + +K+R SS +SKR HK +SRSR RK S + +
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSK 1855
Query: 185 HHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244
HR +RS+S R R RS G++S + R K SP+ +S
Sbjct: 1856 SHRSQTRSRSRSRRRRRSS---RSRSKSRGRRSVSKEKR-------KRSPKHRSK----- 1900
Query: 245 PLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARS 304
SR R ++ S D + +T ARS
Sbjct: 1901 ---------------------------------SRERKRKRSSSRD-----NRKTVRARS 1922
Query: 305 RGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGR-ESRGFQS 363
R + S S S+ R S S ++SP+ R R SR ++
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRS----------------FSISPSRRSRTPSRRSRT 1966
Query: 364 PCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTS 423
P + S PS +P SR S S R S S + RS +
Sbjct: 1967 PSRRSRTPSRRSRTPSRRSRTP----SRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSP 455
+R +SRSP R SRSS RSP
Sbjct: 2023 PLRRRFSRSPI-------RRKRSRSSERGRSP 2047
Score = 52.8 bits (125), Expect = 9e-07
Identities = 54/174 (31%), Positives = 73/174 (41%), Gaps = 32/174 (18%)
Query: 450 RSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRI 509
RS SP S P R + EKD + E + + ++ +K + E +R
Sbjct: 1765 RSAASPVVSSM-PERASESSSEEKD----DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 510 TSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSS 569
+S R R S S SS + S S SRS +R RS RS+TR+ S
Sbjct: 1820 SSLRSR-------------SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSR 1866
Query: 570 SSSRSPSPGSRSRSRSR-------------SRSRSRSRSQSRSYSSADSYSSTR 610
S R S SRS+SR R RS+SR R + RS SS D+ + R
Sbjct: 1867 SRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRS-SSRDNRKTVR 1919
Score = 36.6 bits (83), Expect = 0.069
Identities = 32/116 (27%), Positives = 44/116 (37%), Gaps = 16/116 (13%)
Query: 107 RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDE 166
R K K+ +RK R S P + K SKKHK +H + K K+ E
Sbjct: 78 RYKPDLKEGSRKSR--CVSVQTDPTDEIPTKKSKKHK---------KHKNKKKKKKKEKE 126
Query: 167 KRHKKQSRSRPRKSHRHRHHRCPSRSQS-----SESRPSSCESRHRGRSPEEGQKS 217
K++K+Q K+ H S S SE + E R P E +S
Sbjct: 127 KKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAFGPSETNES 182
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 84.0 bits (206), Expect = 4e-16
Identities = 129/552 (23%), Positives = 185/552 (33%), Gaps = 110/552 (19%)
Query: 87 GATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSS---------YSPSPVKKKKKK 137
G RG ++ P S + S R SSS +SPSP ++K+
Sbjct: 297 GKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSP--RRKRT 354
Query: 138 SSKKHKR------RRSFSKKRRHSSSSPKSKR---------RDEKRHKKQSRSRPRKSHR 182
S ++R RRS S HS SSP+ K+ R++ RH R +SH
Sbjct: 355 PSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRH---DHERTSQSHD 411
Query: 183 HRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPP 242
RH R R + R +SR R E+ Q S R H +D +A+ +R
Sbjct: 412 RRHER---REDTRGKRDREKDSREE-REYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR 467
Query: 243 SQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYD----SGNDTSSPPSTQ 298
+ +R + S TK + SR +D G DT T
Sbjct: 468 RELRDSRDMRDSREMRDYSRD-----TKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTY 522
Query: 299 TSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRES 358
+RS G+ ++ R N +++G + E SRG
Sbjct: 523 PEESRSYGRNHLREESSRTEIR--NESRNESRSEIRNDRMGRSRGRVPELPEKGSRG--- 577
Query: 359 RGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQ 418
+R S + S +S+Y S +RS P +
Sbjct: 578 ----------------------SRGSQIDSHSSNSNY----HDSWETRSSYPE------R 605
Query: 419 SRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRY---SPSRERDPKYSE--- 472
R + R +R S+ + G+R R +R S R+ + ERD + E
Sbjct: 606 DRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRV 665
Query: 473 ------KDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSS 526
+D + RER+R R R R R+R RD E R + R R R
Sbjct: 666 DRVDDRRDERARERDRERERDRERERERERERDREREKE-RELERERARERERER----- 719
Query: 527 SGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSR 586
R R R R R R R R R R R R R R
Sbjct: 720 -------------EKERDRERDRDRDHDRERERERERDREKEREREREERERERERERER 766
Query: 587 SRSRSRSRSQSR 598
R R R R ++R
Sbjct: 767 ERERERERERAR 778
Score = 68.2 bits (165), Expect = 2e-11
Identities = 126/567 (22%), Positives = 206/567 (36%), Gaps = 60/567 (10%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
ER++ RE R + DK+ K K + R+KR ++ +
Sbjct: 763 ERERE-RERERERERARERDKERERQRDWEDKDKGRDDRREKREEI---------REDRN 812
Query: 138 SSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPS---RSQS 194
H R+S + R S SP+ + + H S + ++ HR S R Q
Sbjct: 813 PRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQE 872
Query: 195 SES-RPSSCESRHRGRSPEEGQKSRRRHS-RRCSKTLCKDSPEAQSSRPPSQPLQMLGYL 252
S S PS +GR EE +K R+ S RR + K+ + + + +
Sbjct: 873 SRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRM 932
Query: 253 SARGVI--------TGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARS 304
A+ +I S A D K A + +E D G + + +T + +
Sbjct: 933 RAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETT-SEDGQV 991
Query: 305 RGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSP 364
+KG + K R+ + G++ S S + +G ++ E ++
Sbjct: 992 FSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNG 1051
Query: 365 CLECAEVKKSSL--------VPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRY 416
LE ++ K+ + VP + + + +++ ST S S P P +
Sbjct: 1052 ILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATAT 1111
Query: 417 ------TQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRER---- 466
T + +T++ S+S S S S + P+ ++ + + S R R
Sbjct: 1112 ATTVPATLAATTAAAATSFSTSAITISTS---ATPTNTTNNTFANEDSHRKCHRTRVEKV 1168
Query: 467 -DPKYSEKDSQQRE-----RERARRRRRSYSPMRKRRRDSPSHLEARRI---TSARKRPI 517
P + +D+Q R+ R + RS R SPS+ A R S RKR +
Sbjct: 1169 ETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVL 1228
Query: 518 PYYRPSPSSSGSLSSTSSWYS-----SSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSS 572
+ SL T S S S S R SRS S RRS + S
Sbjct: 1229 HSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHS 1288
Query: 573 RSPSPGSRSRSRSRSR-SRSRSRSQSR 598
RS S SR R + R R R R + R
Sbjct: 1289 RSGSFDSRDRLQERDRYEHDRERERER 1315
Score = 61.6 bits (148), Expect = 2e-09
Identities = 117/553 (21%), Positives = 187/553 (33%), Gaps = 135/553 (24%)
Query: 91 GHSASHDKDLTPPPSSRGKKK---KKKSTRKKRRRSSSYSPSPVKKKKKK----SSKKHK 143
GH S D++ + KKK +KK +KK+ ++ + S KK +
Sbjct: 939 GHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQ 998
Query: 144 RRRSFSKKRRHS---SSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRS---QSSES 197
+++S KKR+ S S + + + K+ R+ P + C ++ + S+
Sbjct: 999 KKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQK 1058
Query: 198 RPSSCESRHRGRS-PEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQM-------- 248
+ + S P+ + + H+ + SP S PP P+
Sbjct: 1059 KEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSP-LSSLLPPPPPVATATATTVPA 1117
Query: 249 -LGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGN-------DTSSPPSTQTS 300
L +A + S SA + T +A+P T+ DS + P
Sbjct: 1118 TLAATTAAAATSFSTSAITIST-SATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIE 1176
Query: 301 SARSR---GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRE 357
A+ R Q++ S G +R SG N S ++ L SR RE
Sbjct: 1177 DAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDRE 1236
Query: 358 SRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYT 417
++ LE +KS + R P SRS+S S SHSSR +P
Sbjct: 1237 ----KTKSLEITGERKSR-IDQLKRGEP----SRSTSSDRQDSRSHSSRRSSPE------ 1281
Query: 418 QSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ 477
S+++ +SRS S+ S+ + E+D +
Sbjct: 1282 ------SDRQVHSRSGSFDSRD-----------------------------RLQERDRYE 1306
Query: 478 RERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWY 537
+RER R RR + R+R D
Sbjct: 1307 HDRERERERRDT----RQREWD-------------------------------------- 1324
Query: 538 SSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQS 597
R A + + R+R R R R R R R R R R S S R R R +
Sbjct: 1325 -----RDADKDWPRNRDRDRLRERERER---ERDKRRDLDRERERLISDSVERDRDRDRD 1376
Query: 598 RSYSSADSYSSTR 610
R++ S+ S R
Sbjct: 1377 RTFESSQIESVKR 1389
Score = 59.7 bits (143), Expect = 8e-09
Identities = 108/576 (18%), Positives = 210/576 (36%), Gaps = 75/576 (13%)
Query: 78 ERDKTC-RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKK 136
ERD+ RE R +++L + +++++K ++R R + +++++
Sbjct: 684 ERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERER 743
Query: 137 KSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSE 196
K+ +R R ++ R + + R+ +R +++ R+R R R R + + +
Sbjct: 744 DREKEREREREERERERE-----RERERERERERERERARERDKERERQRDWEDKDKGRD 798
Query: 197 SRPSSCESRHRGRSPEEG---QKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLS 253
R E R+P +G +KS++R+ S + + SP+ + P G
Sbjct: 799 DRREKREEIREDRNPRDGHDERKSKKRYRNEGSPS-PRQSPKRRREHSPDSDAYNSGDDK 857
Query: 254 ARGVITGSGSAADLFTKTASP--LTTSR-GRSQEYDSGNDTSSPPSTQTSSARSRGQEKG 310
S +++ SP LT R GR +E D P + SS R QE
Sbjct: 858 NEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEED------RKPERKESSRRYEEQELK 911
Query: 311 SPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAE 370
+ K RE SS ++ + R R E
Sbjct: 912 EKVSSVDKQRE---------QTEILESSRMRAQDIIGHHQSEDRETSDRAHD-------E 955
Query: 371 VKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYS 430
KK + + + P+K + R + ++ SP+ Q + + +KR S
Sbjct: 956 NKKKAKI----QKKPIKK-KKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKS 1010
Query: 431 RSPSYSS----------KSGKRSPPSRSSRSRRSPSYSR---YSPSRERDPKYSEKDSQQ 477
+ S S K G R+PP + + S++++ S +
Sbjct: 1011 KGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDE 1070
Query: 478 RERERARRRRRSYSPMRKRRRDSPSHLEA-----RRITSARKRPIPYYRPSPSSSGSLSS 532
+R ++ +PS L + + +A +P + +++ + S
Sbjct: 1071 DVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSF 1130
Query: 533 TSSWYSSSSSRSASRSYSRSRSRSRSRRR-SRTRTSS----------------SSSSRSP 575
++S + S+S + + + + + + S R+ RTR RS
Sbjct: 1131 STSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSS 1190
Query: 576 SPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
S GS +RS + R RS S ++ S D S +R
Sbjct: 1191 SLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKR 1226
Score = 55.1 bits (131), Expect = 2e-07
Identities = 119/597 (19%), Positives = 180/597 (30%), Gaps = 62/597 (10%)
Query: 34 ASITARKPLPRTEPQNNP-----VVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGA 88
+SI P PR + +P + P + H + P S R ++
Sbjct: 340 SSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKG 399
Query: 89 TRGH---SASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRR 145
H S SHD+ +RGK+ ++K +R++R S S + ++ RR
Sbjct: 400 RHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRR 459
Query: 146 RSFSKKRRHSSSSPKSKR-----RDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPS 200
+ + R + R RD R K+SR PR S R + R
Sbjct: 460 DARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD-PRDSRSTRD------AHDYRDREG 512
Query: 201 SCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITG 260
R PEE + R H R S + SR + +M +
Sbjct: 513 RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE 572
Query: 261 SGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSR 320
GS S + + S +DS SS P R R E+ + S
Sbjct: 573 KGSRG----SRGSQIDSHSSNSNYHDSWETRSSYPE------RDRYPERDNRDQARDSSF 622
Query: 321 ELNSGNTSDSGN---SFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLV 377
E G N SSP + L R E R +
Sbjct: 623 ERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDR--------------- 667
Query: 378 PSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSS 437
R + R R R R + +R +
Sbjct: 668 VDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRER 727
Query: 438 KSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRR 497
+ R R R ER+ + + ++RERER R R R R+R+
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQ 787
Query: 498 RDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRS- 556
RD + R ++ I R +P + Y + S S +S R R S
Sbjct: 788 RDWEDKDKGRDDRREKREEIREDR-NPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSP 846
Query: 557 -----------RSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
+ R ++ SRS SP + R + R + R R SS
Sbjct: 847 DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR-QGRWKEEDRKPERKESS 902
Score = 52.8 bits (125), Expect = 9e-07
Identities = 123/510 (24%), Positives = 174/510 (34%), Gaps = 57/510 (11%)
Query: 110 KKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRH 169
K ++++ K+ SP + K S R+ S S KR+ SSPKS +K
Sbjct: 179 KLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRK---SSPKSSSASKKDR 235
Query: 170 KKQSRSRPRKSHRHRHHRCPSRSQSSES---RPSSCESRHRGRSPEEGQKSRRR--HSRR 224
K + S P + S+ + + P E G+ +E K + R R
Sbjct: 236 KTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTR 295
Query: 225 CSKTLCKDSPEAQSSRPPSQPLQMLGY----LSARGVITGSGSAADLFTKTASPLTTSRG 280
K +D + R + G +S+R + S S + + + SP R
Sbjct: 296 DGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSP----RR 351
Query: 281 RSQEYDSGNDTSSPP-----STQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFT 335
+ S T +PP S S + S Q K SP S RE + + T
Sbjct: 352 KRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHD-----HERT 406
Query: 336 TSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSY 395
+ S + E+ +RG+ R S E +SS P G R
Sbjct: 407 SQSHDRRHERRED----TRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDR---- 458
Query: 396 ASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSP 455
+R R R ++ S E R YSR K S R SRS R
Sbjct: 459 -------RDARDTRDRRELRDSRDMRDSREMRDYSRDT-------KESRDPRDSRSTRDA 504
Query: 456 SYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDS--PSHLEARRITSAR 513
Y RD E + R R R S + R +S S E R R
Sbjct: 505 --HDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGR 562
Query: 514 KRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSR-TRTSSSSSS 572
R P S GS S +SS+S+ S +RS R R R R + SS
Sbjct: 563 SRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWE-TRSSYPERDRYPERDNRDQARDSS 621
Query: 573 RSPSPGSRSRSRSRSRSRSRS---RSQSRS 599
G R R +R R + S R Q R+
Sbjct: 622 FERRHGERDRRDNRERDQRPSSPIRHQGRN 651
Score = 50.4 bits (119), Expect = 5e-06
Identities = 61/233 (26%), Positives = 93/233 (39%), Gaps = 24/233 (10%)
Query: 370 EVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSY 429
EV +S L PS + K R SS S+ S+S R + +SP Q R++ + +
Sbjct: 200 EVVRSKLSPSPSLRKSSKSPKRKSSPKSS-SASKKDRKTSAVSSPLLDQQRNSKTNQ--- 255
Query: 430 SRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
S K G R+P S P + ++ KY KD + + + R R
Sbjct: 256 ------SKKKGPRTP------SPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRD 303
Query: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSS--SRSASR 547
+ R++R D P R + A + P SSS S+ +S S R+ S
Sbjct: 304 FERQREKR-DKP-----RSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSP 357
Query: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSY 600
SY R+ + R S + S SS + R RS R + R S+S+
Sbjct: 358 SYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSH 410
Score = 45.1 bits (105), Expect = 2e-04
Identities = 55/215 (25%), Positives = 82/215 (38%), Gaps = 23/215 (10%)
Query: 44 RTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPP 103
R E P V +D K + LG+N R T L + SA D
Sbjct: 1164 RVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGD---- 1219
Query: 104 PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRR----HSS--S 157
G+K+ S + R ++ S + +K + K+ + RS S R+ HSS S
Sbjct: 1220 -DQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRS 1278
Query: 158 SPKSKRRDEKRHKK-QSRSRPRKSHRHRHHR--------CPSRSQSSESRPSSCESRHRG 208
SP+S R+ R SR R ++ R+ H R R ++ +R R
Sbjct: 1279 SPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRD 1338
Query: 209 RSPE---EGQKSRRRHSRRCSKTLCKDSPEAQSSR 240
R E E ++ +RR R + L DS E R
Sbjct: 1339 RLRERERERERDKRRDLDRERERLISDSVERDRDR 1373
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 83.6 bits (205), Expect = 5e-16
Identities = 74/183 (40%), Positives = 95/183 (51%), Gaps = 15/183 (8%)
Query: 420 RSTSSEKRSYSRSPSYSSKS---GKRS-PPSRSSRSR-RSPSYSRY-SPSRERDPKYSEK 473
RS E R SR Y +S G+RS P R RSR R PS SR S SR R +YS
Sbjct: 99 RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRS 158
Query: 474 DSQQRERERARRRRRSYSPMRKRR-RDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSS 532
+ R+R R YS R R R SH + +++R Y R S S S S
Sbjct: 159 PYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSR-----YSRYHSSRSHSKSG 213
Query: 533 TSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSR 592
+S+ SS S S S+S S RS+S S RSR+R+ SSS +RSP S+ +S+SRSRS+
Sbjct: 214 SST---SSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRP 270
Query: 593 SRS 595
+S
Sbjct: 271 PKS 273
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/153 (35%), Positives = 67/153 (43%), Gaps = 20/153 (13%)
Query: 389 CSRSSSYASTRSSSHS----SRSPNPRAS-PRYTQSRSTSSEKR---SYSRSPSYSSKSG 440
CSRS S + R S +S SRSP R+ R SRS E R S+ S YS+
Sbjct: 141 CSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRY 200
Query: 441 KRSPPSRS-SRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRD 499
R SRS S+S S S S S+ + S+ S R R R+R + SP R +R
Sbjct: 201 SRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRK 260
Query: 500 SPSHLEARRITSARKRPIPYYRPSPSSSGSLSS 532
S S S KRP SP G +SS
Sbjct: 261 SKSR-------SRSKRP----PKSPEEEGQMSS 282
Score = 51.2 bits (121), Expect = 3e-06
Identities = 64/185 (34%), Positives = 83/185 (44%), Gaps = 15/185 (8%)
Query: 303 RSR-GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGF 361
RSR G+ +G GG R + G S S S +++G SR R SR
Sbjct: 99 RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRS--RSRGPSCSRSRSRSRYRGSRYS 156
Query: 362 QSPCLEC----AEVKKSSLVPSTARSSPMKGCSRSSS-YASTRSSS-HSSRSPNPRASPR 415
+SP + +S S R S G SSS Y+++R S HSSRS + S
Sbjct: 157 RSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSS- 215
Query: 416 YTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS-RYSPSR---ERDPKYS 471
T SRS S+ K S +R SS S RS SS +R P S R S SR +R PK
Sbjct: 216 -TSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSP 274
Query: 472 EKDSQ 476
E++ Q
Sbjct: 275 EEEGQ 279
Score = 48.9 bits (115), Expect = 1e-05
Identities = 58/178 (32%), Positives = 74/178 (41%), Gaps = 32/178 (17%)
Query: 145 RRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHR-HRHHRCP-SRSQSSESRPSSC 202
RRS S RR S SP+ + R R SRSR R +R R+ R P SRS S SR S
Sbjct: 116 RRSRSYGRR--SRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRS 173
Query: 203 --------ESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSA 254
ESR+ G S R+SR S S + SSR S
Sbjct: 174 PYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSAS----------- 222
Query: 255 RGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSP 312
T S+A +S ++ SR RS+ S + T SPP ++SR + K P
Sbjct: 223 ----TSKSSSAR--RSKSSSVSRSRSRSR---SSSMTRSPPRVSKRKSKSRSRSKRPP 271
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/163 (29%), Positives = 63/163 (38%), Gaps = 29/163 (17%)
Query: 106 SRGKKKKKKSTRKKRR-----------------RSSSYSPSPVKKKKKKSSKKHKRRRSF 148
SR ++ +S R++ R R S YS SP + S+ + S
Sbjct: 118 SRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSR 177
Query: 149 SKKRR------HSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSC 202
S+ R H SSS S R + H +S S KS R S S+SS +R S
Sbjct: 178 SRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHS---KSGSSTSSRSASTSKSSSARRSKS 234
Query: 203 ESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245
S R RS S R R SK K ++S RPP P
Sbjct: 235 SSVSRSRS-RSRSSSMTRSPPRVSKR--KSKSRSRSKRPPKSP 274
Score = 43.5 bits (101), Expect = 6e-04
Identities = 34/73 (46%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 542 SRSASRSYSRSRS---RSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSR 598
+R R RSR R RSR R S S RS SP R RSRSR S SRSRS+SR
Sbjct: 90 ARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSR 149
Query: 599 SYSSADSYSSTRR 611
S S S R
Sbjct: 150 YRGSRYSRSPYSR 162
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/109 (22%), Positives = 47/109 (43%)
Query: 38 ARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHD 97
+R P R+ +P ++ S G H ++ + + R + R + ++S
Sbjct: 161 SRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRS 220
Query: 98 KDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRR 146
+ S+R K S + R RSSS + SP + K+KS + + +R
Sbjct: 221 ASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKR 269
Score = 34.7 bits (78), Expect = 0.26
Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 19/97 (19%)
Query: 105 SSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRR 164
SSR K ST RS+S S S ++ K SS R RS SSS +S R
Sbjct: 205 SSRSHSKSGSSTSS---RSASTSKSSSARRSKSSSVSRSRSRS------RSSSMTRSPPR 255
Query: 165 DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
KR K +SRSR ++ P +S E + SS
Sbjct: 256 VSKR-KSKSRSRSKR---------PPKSPEEEGQMSS 282
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 83.2 bits (204), Expect = 6e-16
Identities = 151/551 (27%), Positives = 203/551 (36%), Gaps = 118/551 (21%)
Query: 121 RRSSSYSPSPVKKKKKKSSKK----------------HKRRRSFSKKR--RHSSSSPKSK 162
RR+ S+ P P++ K S+ K S SKK R+ +SS +SK
Sbjct: 1442 RRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESK 1501
Query: 163 RRDEKRHKKQSRSR-----PRKSHRHRH---------HRCPSRSQSSESRPSSCESRHRG 208
+ Q+R R P K HRH H PS + R S +RH
Sbjct: 1502 NLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNP 1561
Query: 209 -----RSPEE-GQKS--RRRHSRRCSKTLCK------DSPEAQSSRPPSQ------PLQM 248
RSP E Q+S RRH ++ C SP +S R PSQ P +
Sbjct: 1562 SWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERS 1621
Query: 249 LGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQE-YDSGNDTSSPPSTQTSSARSRGQ 307
LS RG+ + S + RG SQ + S ++ S ++ S S +
Sbjct: 1622 CHSLSERGLHSPSQRS-------------HRGPSQRRHHSPSERSHRSPSERSHRSSSER 1668
Query: 308 EKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLE 367
SPS +S S + S + SP + + RG R SP
Sbjct: 1669 RHRSPS---QRSHRGPSERSHCSPSERRHRSPSQR---------SHRGPSERRHHSPS-- 1714
Query: 368 CAEVKKSSLVPST-ARSSPMKGCSRSSSYASTRSSS---HSSRSPNPRASPRYTQSRSTS 423
K+S P+ + SP + S S S S S H S S SP +S +
Sbjct: 1715 ----KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPS-ERSHCSP 1769
Query: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPS-YSRYSPSR-------ERDPKYSEKDS 475
SE+R S S ++S S S RS SPS R+SP ER + +
Sbjct: 1770 SERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERR 1829
Query: 476 QQRERERARRR--RRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSST 533
R ER+ RR RS+SP K SHL P+ R SPS SS+
Sbjct: 1830 SHRSFERSHRRISERSHSPSEK------SHLS----------PLERSRCSPSERRGHSSS 1873
Query: 534 SSWYSSSSSRS--ASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPS-PGSRSRSRSRSRSR 590
S S RS + + R+ RS R S RT S S P P R+ RSR
Sbjct: 1874 GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSR 1933
Query: 591 SRSRSQSRSYS 601
+ YS
Sbjct: 1934 RSPLKEGLKYS 1944
Score = 77.0 bits (188), Expect = 5e-14
Identities = 137/534 (25%), Positives = 206/534 (38%), Gaps = 89/534 (16%)
Query: 128 PSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187
PS +K+ K+ + K + ++ + + + + R + RP + +
Sbjct: 1402 PSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPK----- 1456
Query: 188 CPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSP---------EAQS 238
P+ SQS + ++ + R+ ++ SR + + ++T ++S +A+
Sbjct: 1457 -PTDSQSGIAFQTASVGQPL-RTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARG 1514
Query: 239 SRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQ 298
P P++ + + +T F + +P S R++ S + SP
Sbjct: 1515 RILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE-RTRHNPSWRNHRSPSERS 1573
Query: 299 TSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRES 358
S+ R S S SR+ +S S S S+ + S +N + SP R S
Sbjct: 1574 QRSSLERRHHSPSQRSHCSPSRKNHS---SPSERSWRSPSQRN------HCSPPERSCHS 1624
Query: 359 ---RGFQSPCLECAEVKKSSLVPSTARS-SPMKGCSRSSSYASTRSSSH---------SS 405
RG SP ++S PS R SP + RS S S RSSS S
Sbjct: 1625 LSERGLHSPS------QRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSH 1678
Query: 406 RSPNPRA--SPRYTQSRSTS-------SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPS 456
R P+ R+ SP + RS S SE+R +S S +RS S S RS SPS
Sbjct: 1679 RGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS 1738
Query: 457 Y-SRYSPSRERDPKYSEKD----------SQQRERERARRRRRSYSPMRKRRRDSPSHLE 505
S +SPS R SE+ S R R+ RR +SP K SPS
Sbjct: 1739 ERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHH-SPSE-R 1796
Query: 506 ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRS--- 562
+ S R+R P R S SL S + S S R + RS+ RS R R S
Sbjct: 1797 SHHSPSERRRHSPLER----SRHSLLERS--HRSPSERRSHRSFERSHRRISERSHSPSE 1850
Query: 563 --------RTRTSSSSSSRSPSPGSRSRSRSRSRSRSRS-----RSQSRSYSSA 603
R+R S S S G S S RS S R+ RS+ S+
Sbjct: 1851 KSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSS 1904
Score = 76.6 bits (187), Expect = 6e-14
Identities = 143/582 (24%), Positives = 213/582 (36%), Gaps = 94/582 (16%)
Query: 104 PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKR 163
P S + + + K R + +S S P+K+ +K+ ++ R F R + SP +
Sbjct: 1263 PESDSESTQNEKRAKVRTKKTSDSKYPMKR----ITKRLRKHRKFYTNSRTTIESPSREL 1318
Query: 164 RDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSS----ESRPSSCESRHR-----GRSPEEG 214
R K+ ++ + R + PS+ + +S + ++ HR GR P +G
Sbjct: 1319 AAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDG 1378
Query: 215 QK------SRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITG-------- 260
+ S+ + ++ ++ C S + R + + ++ G
Sbjct: 1379 TRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSA 1438
Query: 261 -------------------SGSAADLFTKTAS---PLTT----SRGRSQEYDSGNDTSSP 294
+ S + + +TAS PL T S RS++ N+TSS
Sbjct: 1439 QQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQ 1498
Query: 295 PSTQTSSARSRGQEKGS--PSGGLSKS--RELNSGNTSDSGN--SF----TTSSP----Q 340
S S+ +R Q +G P + ++ R L T N SF T P +
Sbjct: 1499 ESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTR 1558
Query: 341 NKGAMLENLSPTSRGRES---RGFQSPC--LECAEVKKSSLVPSTAR----------SSP 385
+ + + SP+ R + S R SP C+ +K+ PS S P
Sbjct: 1559 HNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPP 1618
Query: 386 MKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPP 445
+ C S S S R P S R S S S + RS SS+ RSP
Sbjct: 1619 ERSCHSLSERGLHSPSQRSHRGP----SQRRHHSPSERSHRSPSERSHRSSSERRHRSPS 1674
Query: 446 SRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLE 505
RS R S+ S R R P R + +R SP R+ R SPS
Sbjct: 1675 QRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHR-SPSE-R 1732
Query: 506 ARRITSARKRPIPYYR--PSPSSSGSLS-STSSWYSSSSSRSASRSYSRSRSRSRSRRRS 562
+ S R P R SPS S S S S S R S S R S S S
Sbjct: 1733 SHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792
Query: 563 RTRTS--SSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
+ S S S R SP RSR RS RS S+ RS+ S
Sbjct: 1793 PSERSHHSPSERRRHSPLERSRHSLLERSH-RSPSERRSHRS 1833
Score = 70.5 bits (171), Expect = 4e-12
Identities = 122/467 (26%), Positives = 173/467 (37%), Gaps = 65/467 (13%)
Query: 76 SWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKK 135
S+ R++T R H+ S +P ++ ++S+ ++R S S +K
Sbjct: 1543 SFYRERTPRGPSERTRHNPSWRNHRSP------SERSQRSSLERRHHSPSQRSHCSPSRK 1596
Query: 136 KKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPS----R 191
SS + RS S+ R H S +S +R R + R H PS R
Sbjct: 1597 NHSSPSERSWRSPSQ-RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHR 1655
Query: 192 SQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGY 251
S S S SS E RH RSP S+R H ++ C SP + R PSQ
Sbjct: 1656 SPSERSHRSSSERRH--RSP-----SQRSHRGPSERSHC--SPSERRHRSPSQ------- 1699
Query: 252 LSARGVITGSGSAADLFTKTASPLTTSRG---RSQEYDSGNDTSSPPSTQTSSARSRGQE 308
S RG + + + + R RS S SP + S R
Sbjct: 1700 RSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHC 1759
Query: 309 KGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLEC 368
S S S E + S+ + + + + + SP+ R R S
Sbjct: 1760 SPSERSHCSPS-ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSP--------- 1809
Query: 369 AEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRA--SPRYTQSRSTSSEK 426
E + SL+ + R SP + S S S R S S SP+ ++ SP +SR + SE+
Sbjct: 1810 LERSRHSLLERSHR-SPSERRSHRSFERSHRRISERSHSPSEKSHLSP-LERSRCSPSER 1867
Query: 427 RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRR 486
R +S S ++ S S RS RSPS R + ER R R
Sbjct: 1868 RGHS--------SSGKTCHSPSERSHRSPSGMRQGRTSERS-----------HRSSCERT 1908
Query: 487 RRSYSPMRKRRRDSPSHL--EARRITSARKRPIPYYRPSPSSSGSLS 531
R S S MR R +H R S K + Y P S SLS
Sbjct: 1909 RHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLS 1955
Score = 47.4 bits (111), Expect = 4e-05
Identities = 53/201 (26%), Positives = 72/201 (35%), Gaps = 24/201 (11%)
Query: 43 PRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTP 102
P +P + PSE+ H +E + ER R HS S +P
Sbjct: 1713 PSKRSHRSPARRSHRSPSER-SHHSPSERSHHSPSER----------RHHSPSERSHCSP 1761
Query: 103 PPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSK 162
S +++ RR +SPS +K S + S S++RRHS
Sbjct: 1762 SERSHCSPSERRHRSPSERRH--HSPS----EKSHHSPSERSHHSPSERRRHSPLERSRH 1815
Query: 163 RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHS 222
E+ H+ S R +S H R RS S + SP E RR HS
Sbjct: 1816 SLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSE----RRGHS 1871
Query: 223 RRCSKTLCKDSPEAQSSRPPS 243
S C SP +S R PS
Sbjct: 1872 --SSGKTC-HSPSERSHRSPS 1889
Score = 35.0 bits (79), Expect = 0.20
Identities = 29/140 (20%), Positives = 62/140 (44%), Gaps = 2/140 (1%)
Query: 371 VKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNP-RASPRYTQSRSTSSEKRSY 429
+++S + PS ++ S+S + ++ S S+SP P + R Q +++
Sbjct: 1189 IRRSPISPSQRKAKIYTQASKSPT-STIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTK 1247
Query: 430 SRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
+R+P + + + P S S ++ ++ + D KY K +R R+ + S
Sbjct: 1248 TRAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNS 1307
Query: 490 YSPMRKRRRDSPSHLEARRI 509
+ + R+ +HL +RI
Sbjct: 1308 RTTIESPSRELAAHLRRKRI 1327
Score = 30.0 bits (66), Expect = 6.5
Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 23/137 (16%)
Query: 475 SQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTS 534
S+ RER+R P+ +R SPS +A+ T A K SP+S+ L S
Sbjct: 1179 SKYRERDR---------PVIRRSPISPSQRKAKIYTQASK--------SPTSTIDLQS-- 1219
Query: 535 SWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSR 594
S S + + Y R RSR +T+T + + S S S +++ R
Sbjct: 1220 ---GPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSES-TQNEKR 1275
Query: 595 SQSRSYSSADSYSSTRR 611
++ R+ ++DS +R
Sbjct: 1276 AKVRTKKTSDSKYPMKR 1292
Score = 29.6 bits (65), Expect = 8.5
Identities = 39/152 (25%), Positives = 60/152 (39%), Gaps = 29/152 (19%)
Query: 90 RGHSASHDKDLTP-------PPSSRGKKKKKKSTRKKRRRSSSYSPSPVKK----KKKKS 138
R HS S L+P P RG K+ RS SPS +++ ++
Sbjct: 1844 RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHR-SPSGMRQGRTSERSHR 1902
Query: 139 SKKHKRRRSFSKKR-------RHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSR 191
S + R S S+ R H S S +S+R K K S R SH S
Sbjct: 1903 SSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSH--------SL 1954
Query: 192 SQSSESRPSSCESRHRGRSPEEGQKSRRRHSR 223
S+ +++ + + H ++P+ GQ R +R
Sbjct: 1955 SRDFKNQTTLLGTTH--KNPKAGQVWRPEATR 1984
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 82.8 bits (203), Expect = 8e-16
Identities = 60/186 (32%), Positives = 86/186 (46%), Gaps = 25/186 (13%)
Query: 425 EKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERAR 484
EKR +SRS S SR RR+PS SR+ SR R + S S+ R R ++
Sbjct: 244 EKRRHSRSRS-------------RSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSP 290
Query: 485 RRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRS 544
RRRRS+S R RR S S ++ K+ S + S+ ++ SRS
Sbjct: 291 RRRRSHSRERGRRSRSTSKTRDKKKEDKEKKR------------SKTPPKSYSTARRSRS 338
Query: 545 ASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSAD 604
ASR R RSRS +R + R+ SRSPSP + + + + + RSR + +S
Sbjct: 339 ASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKK 398
Query: 605 SYSSTR 610
S +
Sbjct: 399 KKSKDK 404
Score = 61.6 bits (148), Expect = 2e-09
Identities = 52/211 (24%), Positives = 91/211 (43%), Gaps = 11/211 (5%)
Query: 100 LTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSP 159
++P S K+ + K+ R + S + ++ KK+ ++H R RS S++RR SSS
Sbjct: 206 VSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
Query: 160 KSKRRDEKRHKKQSRSRP-RKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSR 218
+ R R + S+SR R+S R R SR + SR + S+ R + E+ +K R
Sbjct: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRST---SKTRDKKKEDKEKKR 322
Query: 219 RRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS 278
SKT K A+ SR S+ + S S +++ SP
Sbjct: 323 -------SKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK 375
Query: 279 RGRSQEYDSGNDTSSPPSTQTSSARSRGQEK 309
+ + ++ D + + +S+ +EK
Sbjct: 376 KEKKKDKDKERSRDERERSTSKKKKSKDKEK 406
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/172 (29%), Positives = 80/172 (46%), Gaps = 17/172 (9%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
E DK +E S S + P SSR ++ + +S RRRS S K + ++
Sbjct: 238 EPDK--KEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRS----RRRSHS------KSRSRR 285
Query: 138 SSKKHKRRRSFSKKR-RHSSSSPKSK-RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSS 195
SK +RRRS S++R R S S+ K++ ++ E + KK+S++ P+ R R SR +
Sbjct: 286 RSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR 345
Query: 196 ESRPSSCESRHRGRSPE---EGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244
S S + RSP+ S RRH + K K+ + R S+
Sbjct: 346 RRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSK 397
Score = 57.4 bits (137), Expect = 4e-08
Identities = 47/141 (33%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 472 EKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLS 531
+ D+ +E E A +R R + + E RR + +R R PS
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPS-------- 262
Query: 532 STSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRS 591
SS RS SRS RS S+SRSRRRS++ S SR G RSRS S++R +
Sbjct: 263 ------SSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER--GRRSRSTSKTRDKK 314
Query: 592 R-SRSQSRSYSSADSYSSTRR 611
+ + + RS + SYS+ RR
Sbjct: 315 KEDKEKKRSKTPPKSYSTARR 335
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/154 (30%), Positives = 73/154 (47%), Gaps = 27/154 (17%)
Query: 378 PSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRAS---PRYTQSRSTSS---------- 424
PS++R + SR S++ +RS S +SP R S R +SRSTS
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRSRRRS-KSPRRRRSHSRERGRRSRSTSKTRDKKKEDKE 319
Query: 425 EKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPK-----------YSEK 473
+KRS + SYS+ RS SR R RRS S +R SP + R PK + ++
Sbjct: 320 KKRSKTPPKSYSTARRSRSA-SRERRRRRSRSGTR-SPKKPRSPKRKLSRSPSPRRHKKE 377
Query: 474 DSQQRERERARRRRRSYSPMRKRRRDSPSHLEAR 507
+ +++ER+R R + +K+ +D E +
Sbjct: 378 KKKDKDKERSRDERERSTSKKKKSKDKEKDRERK 411
Score = 50.4 bits (119), Expect = 5e-06
Identities = 51/192 (26%), Positives = 74/192 (38%), Gaps = 14/192 (7%)
Query: 379 STARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYS----RSPS 434
S R +P R S S R S SRS SPR +S S +RS S R
Sbjct: 255 SRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKK 314
Query: 435 YSSKSGKRS--PPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSP 492
K KRS PP S +RRS S SRER + S ++ ++ R+ +R+ S SP
Sbjct: 315 KEDKEKKRSKTPPKSYSTARRS-----RSASRERRRRRSRSGTRSPKKPRSPKRKLSRSP 369
Query: 493 M-RKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR 551
R+ +++ + R R+R + S S S + +R Y
Sbjct: 370 SPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE--SDKDVKQVTRDYDE 427
Query: 552 SRSRSRSRRRSR 563
S + +
Sbjct: 428 EEQGYDSEKEKK 439
Score = 50.1 bits (118), Expect = 6e-06
Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 12/148 (8%)
Query: 90 RGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFS 149
R HS + +R KKK+ K ++ + SYS + ++ + +S++ +RRRS
Sbjct: 294 RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTA---RRSRSASRERRRRRS-- 348
Query: 150 KKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGR 209
R + SPK K R KR K SRS + H+ + + +S + R S + + +
Sbjct: 349 ---RSGTRSPK-KPRSPKR--KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSK 402
Query: 210 SPEEGQKSRRRHSRRCSKTLCKDSPEAQ 237
E+ + R+ S + K + +D E +
Sbjct: 403 DKEK-DRERKSESDKDVKQVTRDYDEEE 429
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 11/145 (7%)
Query: 74 TNSWERDKTCRELGATRGHSAS--HDKDLTPPPSSRGKKKKKKSTRKKRR----RSSSYS 127
++S ER + R TR K PP S ++ +S ++RR RS + S
Sbjct: 295 SHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRS 354
Query: 128 PSPVKKKKKK-----SSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHR 182
P + K+K S ++HK+ + K + S + +K+ K + + R RKS
Sbjct: 355 PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES 414
Query: 183 HRHHRCPSRSQSSESRPSSCESRHR 207
+ + +R E + E +
Sbjct: 415 DKDVKQVTRDYDEEEQGYDSEKEKK 439
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/203 (25%), Positives = 81/203 (39%), Gaps = 26/203 (12%)
Query: 300 SSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESR 359
S +RSR + + +PS + S S +S + S ++K RGR SR
Sbjct: 249 SRSRSRSRRRRTPSSSRHRRSRSRSRRRS---HSKSRSRRRSKSPRRRRSHSRERGRRSR 305
Query: 360 GF---QSPCLECAEVKKSSLVP---STARSSPMKGCSRSSSYASTRSSSHS--------- 404
+ E E K+S P STAR S + SR +RS + S
Sbjct: 306 STSKTRDKKKEDKEKKRSKTPPKSYSTARRS--RSASRERRRRRSRSGTRSPKKPRSPKR 363
Query: 405 --SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSP 462
SRSP+PR R+ + + +K S+ K+S R R+S S
Sbjct: 364 KLSRSPSPR---RHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQ 420
Query: 463 -SRERDPKYSEKDSQQRERERAR 484
+R+ D + DS++ ++E +
Sbjct: 421 VTRDYDEEEQGYDSEKEKKEEKK 443
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/77 (36%), Positives = 34/77 (44%)
Query: 523 SPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSR 582
SPS SS + R A S + + + R S S S R +P S
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
Query: 583 SRSRSRSRSRSRSQSRS 599
RSRSRSR RS S+SRS
Sbjct: 267 RRSRSRSRRRSHSKSRS 283
Score = 36.6 bits (83), Expect = 0.069
Identities = 60/240 (25%), Positives = 81/240 (33%), Gaps = 62/240 (25%)
Query: 269 TKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTS 328
T ++S SR RS+ S S RS +E+G S SK+R+
Sbjct: 260 TPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK---- 315
Query: 329 DSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVP---STARSSP 385
E E K+S P STAR
Sbjct: 316 --------------------------------------EDKEKKRSKTPPKSYSTARR-- 335
Query: 386 MKGCSRSSSYASTRSSSHS-SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSP 444
SRS+S R S S +RSP SP+ SRS S + + K K
Sbjct: 336 ----SRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK------KKDKDKE 385
Query: 445 PSRSSRSRRSPSYSRYSPSRERD---PKYSEKDSQQRERERARRRRRSYSPMRKRRRDSP 501
SR R RS S + S +E+D S+KD +Q R+ + S K+ P
Sbjct: 386 RSRDER-ERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
Score = 34.7 bits (78), Expect = 0.26
Identities = 23/99 (23%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 101 TPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKK--RRHSSSS 158
+P P K+KKK +++ R S S KKKK K +K + R+S S K ++ +
Sbjct: 368 SPSPRRHKKEKKKDKDKERSRDERERSTS--KKKKSKDKEKDRERKSESDKDVKQVTRDY 425
Query: 159 PKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSES 197
+ ++ + +K+ +P ++ + C + +S
Sbjct: 426 DEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDS 464
Score = 30.4 bits (67), Expect = 5.0
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 10/86 (11%)
Query: 530 LSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR- 588
L+ ++ S S +S + S + R R +++ + SRSRSRSR
Sbjct: 198 LNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRR 257
Query: 589 ---------SRSRSRSQSRSYSSADS 605
RSRSRS+ RS+S + S
Sbjct: 258 RRTPSSSRHRRSRSRSRRRSHSKSRS 283
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 82.8 bits (203), Expect = 8e-16
Identities = 134/624 (21%), Positives = 220/624 (35%), Gaps = 111/624 (17%)
Query: 13 EKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPSEKLGQHLATEPL 72
E+FWRG + E+ R TEP +N ++ E+ + E
Sbjct: 377 ERFWRGG-------QYENF-------RVQYTETEPYHN--YRERERERERENRQRERERE 420
Query: 73 GTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVK 132
ER++ RE R H ++ R + K+ + R+ R R K
Sbjct: 421 RERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEK 480
Query: 133 KKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKS-------HRHRH 185
K K S + R++ K+ +++ P+ KR DE + + P+K R R
Sbjct: 481 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR 540
Query: 186 HRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245
R S S +S S S SR S +SR R S S + ++SSR S
Sbjct: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYS-------SRSSRHSS-- 591
Query: 246 LQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPP---------- 295
+GS S + F+ + SP T + + + PP
Sbjct: 592 ------------FSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKK 639
Query: 296 ---------STQTSSARSRGQEKGSPSGGLSKSRELN--------SGNTSDSGNSFTTSS 338
+T+T++ + G P K R SG+ S SG+S++ SS
Sbjct: 640 PAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSS 699
Query: 339 PQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAST 398
+++ + ++ SS+ +T+ SS YA
Sbjct: 700 SRSRSLSVSSV------------------------SSVSSATSSSSSAHSVDSEDMYADL 735
Query: 399 RS--SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPS 456
S SS SSRSP P + + + R S++ K + P +S + PS
Sbjct: 736 ASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPS 795
Query: 457 YSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRP 516
+ +P P ++ + +E + R+R PS + R+ P
Sbjct: 796 TPQQAP-----PGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKD-------RQSP 843
Query: 517 IPYYRPSPS-SSGSLSSTSSWYSSSSSRSASRSY-SRSRSRSRSRRRSRTRTSSSSSSRS 574
P RP+ S GS S S R S++ + R+R + S SSS +
Sbjct: 844 PPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVT 903
Query: 575 PSPGSRSRSRSRSRSRSRSRSQSR 598
PG S + S ++ + SR
Sbjct: 904 SVPGKASDPGAASTKSGKASTLSR 927
Score = 69.3 bits (168), Expect = 1e-11
Identities = 78/250 (31%), Positives = 112/250 (44%), Gaps = 38/250 (15%)
Query: 384 SPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRS 443
SP + R + AS+ S+S+SSRS + + S S S RS SRS SYSS S + S
Sbjct: 534 SPSRARRRRKTSASSASASNSSRSSSR------SSSYSGSGSSRSRSRSSSYSSYSSRSS 587
Query: 444 PPSRSSRSR-RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPS 502
S S SR RS S+S SPS P + S + + E A ++ K+ P+
Sbjct: 588 RHSSFSGSRSRSRSFSS-SPSPSPTPS-PHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPA 645
Query: 503 HLEARRITS-------------ARKRPIPYYRPSP--SSSGSLSSTSSWYSSSSSRSASR 547
+A + T+ AR++ P P + SGS S + S YS SSSRS S
Sbjct: 646 PPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSL 705
Query: 548 SYSRSRSRSRSRRRSRTRTS--------------SSSSSRSPSPGSRSRSRSRSRSRSRS 593
S S S S + S + S SS+SSRSP+P + + +S+
Sbjct: 706 SVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGV 765
Query: 594 RSQSRSYSSA 603
+ + R S+
Sbjct: 766 KEEKRKRDSS 775
Score = 65.5 bits (158), Expect = 1e-10
Identities = 78/256 (30%), Positives = 101/256 (39%), Gaps = 24/256 (9%)
Query: 359 RGFQSPCLECAEVKKSSLV--PSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRY 416
R Q P + KK + P R+ K R S + S S R
Sbjct: 486 RSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTS 545
Query: 417 TQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR-RSPSYSRYSPSRERDPKYSEKDS 475
S S S+ RS SRS SYS S SSRSR RS SYS YS R +S S
Sbjct: 546 ASSASASNSSRSSSRSSSYSG--------SGSSRSRSRSSSYSSYSSRSSRHSSFSGSRS 597
Query: 476 QQRERERARRRRRSYSPMRK--RRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSST 533
+ R + + SP R R + P+ + + K+P P P + + T
Sbjct: 598 RSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAP-----PPAPPQATKT 652
Query: 534 SSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRS 593
++ + R R +R+ R RT + S S S S S S S SRSRS S
Sbjct: 653 TAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGS------SYSGSSSRSRSLS 706
Query: 594 RSQSRSYSSADSYSST 609
S S SSA S SS+
Sbjct: 707 VSSVSSVSSATSSSSS 722
Score = 61.6 bits (148), Expect = 2e-09
Identities = 95/455 (20%), Positives = 160/455 (35%), Gaps = 63/455 (13%)
Query: 163 RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHS 222
R E+ ++++R R R+ R R R + E + R R EE ++ R +
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAK-- 459
Query: 223 RRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRS 282
+D + Q R R
Sbjct: 460 --------RDEKDRQHR--------------------------------------DRDRE 473
Query: 283 QEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNK 342
+E + P S Q S ++ +K + + G R +D S K
Sbjct: 474 KEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKR-------ADEWKDPWRRSKSPK 526
Query: 343 GAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAS--TRS 400
+ ++SP+ R + S + SS S + S + SRSSSY+S +RS
Sbjct: 527 KKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRS 586
Query: 401 SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSS-RSRRSPSYSR 459
S HSS S + S ++ S S S + PS +K PP ++ +S + P+
Sbjct: 587 SRHSSFSGSRSRSRSFSSSPSPSPTPSPHR--PSIRTKGEPAPPPGKAGEKSVKKPAPPP 644
Query: 460 YSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRI---TSARKRP 516
P + + ++ + ARR+ R +RR S S + +S+R R
Sbjct: 645 APPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRS 704
Query: 517 IPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPS 576
+ S SS + SS+S+ S A + S + SRS ++TR S +
Sbjct: 705 LSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDG 764
Query: 577 PGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
R R S +S S+ S+ ++
Sbjct: 765 VKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQ 799
Score = 44.7 bits (104), Expect = 3e-04
Identities = 51/199 (25%), Positives = 79/199 (39%), Gaps = 22/199 (11%)
Query: 429 YSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRR 488
Y+ + Y + + R +R R RER + E++ ++ ER++ R+RR+
Sbjct: 392 YTETEPYHNYRERERERERENRQRERERERERDRERERRQRERERE-REHERDKERQRRK 450
Query: 489 SYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRS 548
+ +RD R ++R +P P S S + ++ + +
Sbjct: 451 EEWERERAKRDEKDRQHRDR-DREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQ- 508
Query: 549 YSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSR------------SRSRSRS------- 589
R+ RRS++ S SPS R R SRS SRS
Sbjct: 509 VKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSG 568
Query: 590 RSRSRSQSRSYSSADSYSS 608
SRSRS+S SYSS S SS
Sbjct: 569 SSRSRSRSSSYSSYSSRSS 587
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 82.0 bits (201), Expect = 1e-15
Identities = 88/299 (29%), Positives = 124/299 (41%), Gaps = 37/299 (12%)
Query: 338 SPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKS--------SLVPSTARSSPMKGC 389
+PQ LE + R RE++ F S +E K + S S +RSS
Sbjct: 267 TPQAAAKELEEVM--KRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 324
Query: 390 SRSSSYASTRSSSHS---SRSPNPRASPRYTQSRSTSSEKR-SYSRSPSYSSKSGKRSPP 445
R S + RS SH+ SR + R S + RS S E+R S SRS S + R
Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 384
Query: 446 SRSSRSRRSPSYSRYSPSRERDP-----------KYSEKDSQQ-RERERARRRRRSYSPM 493
R + +ER+ K EKD ++ +E++R R R + +
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 444
Query: 494 RKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSR 553
R + ++ E R R + I R S + S+ +S SRS+SR R R
Sbjct: 445 RDKEKEKEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRSYNASRRSRSSSRERRRRR 501
Query: 554 SRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSR--------SRSRSRSRSQSRSYSSAD 604
SRS SR ++T SSRSPSP SR++ + S R R RS S SS D
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560
Score = 56.6 bits (135), Expect = 6e-08
Identities = 41/175 (23%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Query: 74 TNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSP--- 130
+ S R K + +R H+ S + S KK+ KS +++ RS S+S
Sbjct: 320 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379
Query: 131 ----VKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHK--KQSRSRPRKSHRHR 184
+K+K++ K ++ R K+R K+K RD++R K ++ + + R+ R +
Sbjct: 380 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 439
Query: 185 HHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSS 239
H R + E + R + RS E +K ++ R S ++SS
Sbjct: 440 EHE-KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493
Score = 55.5 bits (132), Expect = 1e-07
Identities = 82/379 (21%), Positives = 133/379 (35%), Gaps = 40/379 (10%)
Query: 102 PPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKS 161
P + + K+ + K+ R + S+ + ++ + KS+++ K RS S R S SS KS
Sbjct: 264 PEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNER-KGGRSRSHTRSKSRSSSKS 322
Query: 162 -KRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRR- 219
RR + K +SRS R R + R RS+S + S R + RS + R+
Sbjct: 323 HSRRKRSQSKHRSRSHNRSRSRQKDRR---RSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379
Query: 220 -RHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS 278
R + + + + E + R + + RG + +
Sbjct: 380 TREKIKEKERVKEKDREKEREREKEREKE-----KERGKNKDRDKEREKDREKDKEKDRE 434
Query: 279 RGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSS 338
R R +E++ D R + +S+E++ D S T
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREK-----------DRSKEIDEKRKKDK-KSRTPPR 482
Query: 339 PQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAST 398
N + S R R SR SS P T+++ K SRS S S
Sbjct: 483 SYNASRRSRSSSRERRRRRSR-------------SSSRSPRTSKTIKRKS-SRSPSPRSR 528
Query: 399 RSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS 458
S R + RSTS K S R K K S + + P S
Sbjct: 529 NKKDKKREKERDHISERRERERSTSMRKSSNDRDG--KEKLEKNSTSLKEKEHNKEPDSS 586
Query: 459 RYSPSRERDPKYSEKDSQQ 477
++D +E++ Q
Sbjct: 587 VSKEVDDKDAPRTEENKIQ 605
Score = 53.9 bits (128), Expect = 4e-07
Identities = 88/361 (24%), Positives = 130/361 (36%), Gaps = 70/361 (19%)
Query: 171 KQSRSRPRKSHRHRHH-RCPSRSQS-SESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKT 228
+ +S RK R R H R SRS S S SR +S+HR RS + R+ RR SK+
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRSKS 353
Query: 229 LCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSG 288
K +++ R SR RS D
Sbjct: 354 PHKKRSKSRERRK------------------------------------SRSRSHSRDKR 377
Query: 289 NDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLEN 348
DT + + + +EK + RE + G + + K +
Sbjct: 378 KDTREKIK-EKERVKEKDREK-------EREREKEREKEKERGKNKDRDKEREKDREKDK 429
Query: 349 LSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSP 408
R RE + E K+ R RS R SR+P
Sbjct: 430 EKDREREREKEHEKDRDKE----KEKEQDKEKEREK-----DRSKEIDEKRKKDKKSRTP 480
Query: 409 NPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDP 468
PR+ +SRS+S E+R R S SS R+ + +S RSPS + ++
Sbjct: 481 -PRSYNASRRSRSSSRERR---RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKRE 536
Query: 469 KYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSG 528
K + S++RERER+ R+S RD LE + TS +++ + P SS
Sbjct: 537 KERDHISERRERERSTSMRKS-----SNDRDGKEKLE-KNSTSLKEKE---HNKEPDSSV 587
Query: 529 S 529
S
Sbjct: 588 S 588
Score = 53.5 bits (127), Expect = 5e-07
Identities = 31/76 (40%), Positives = 44/76 (57%)
Query: 535 SWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSR 594
S+ S++ + +S R RSRS RS++R+SS S SR S+ RSRS +RSRSR +
Sbjct: 287 SFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 346
Query: 595 SQSRSYSSADSYSSTR 610
+ RS S S +R
Sbjct: 347 DRRRSKSPHKKRSKSR 362
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 8/165 (4%)
Query: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
RE +R S S DK + K++ K+ R+K R ++ K K K +
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 144 ---RRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRH-HRCPSRSQSSESRP 199
R + K R K RD+++ K+Q + + R+ R + + + S + P
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 200 SSCESRHRGRSPEEGQKSRRRHSR----RCSKTLCKDSPEAQSSR 240
S + R RS ++ RR S R SKT+ + S + S R
Sbjct: 482 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR 526
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/182 (25%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 78 ERDKTC-RELGATRGHSASHDKDLTPPPSSRGKKKK---------KKSTRKKRRRSSSYS 127
E+DK RE + H DK+ +++K +K +K R SY+
Sbjct: 426 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYN 485
Query: 128 PSPVKKKKKKSSKKHKRRRSFSKKR---------RHSSSSPKSKRRDEKRHKKQSRSRPR 178
S ++ + SS++ +RRRS S R R SS SP + R+ K+ KK+ + R
Sbjct: 486 AS---RRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN-KKDKKREKERDH 541
Query: 179 KSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQS 238
S R R S +SS R + S +E + ++ S + KD+P +
Sbjct: 542 ISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEE 601
Query: 239 SR 240
++
Sbjct: 602 NK 603
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 9/142 (6%)
Query: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
R+ G +R H+ S + SS+ ++K+S K R RS + S S ++K ++ SK
Sbjct: 303 RKGGRSRSHTRSKSRS-----SSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRSKSPH 355
Query: 144 RRRSFSKKRR--HSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
++RS S++RR S S + KR+D + K+ K R R + E +
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 202 CESRHRGRSPEEGQKSRRRHSR 223
+ R + E+ ++ R R
Sbjct: 416 DRDKEREKDREKDKEKDRERER 437
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/190 (26%), Positives = 80/190 (42%), Gaps = 16/190 (8%)
Query: 68 ATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKK-RRRSSSY 126
A EP S ER K R TR S S K + S+ K + + R + R++
Sbjct: 292 AIEPESGKSNER-KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRR 350
Query: 127 SPSPVKKKKKKSSKKHKRRRSFSK-KRRHSSSSPKSKRR--DEKRHKKQSRSRPRKSHRH 183
S SP KK+ K ++ R RS S+ KR+ + K K R ++ R K++ R + R+ +
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410
Query: 184 R-------HHRCPSRSQSSE-SRPSSCESRH---RGRSPEEGQKSRRRHSRRCSKTLCKD 232
R R R + E R E H R + E+ Q + + SK + +
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 233 SPEAQSSRPP 242
+ + SR P
Sbjct: 471 RKKDKKSRTP 480
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 540 SSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRS------RS 593
S+ R RS S +RS+SRS +S +R S S +RSRSR + R RS RS
Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 359
Query: 594 RSQSRSYSSADSYSSTRR 611
+S+ R S + S+S +R
Sbjct: 360 KSRERRKSRSRSHSRDKR 377
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/166 (25%), Positives = 67/166 (40%), Gaps = 18/166 (10%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
ER+K RE RG + DK+ ++K K ++R R + K+K+K+
Sbjct: 400 EREKE-REKEKERGKNKDRDKE------REKDREKDKEKDREREREKEHEKDRDKEKEKE 452
Query: 138 SSKKHKRRRSFSK----KRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
K+ +R + SK KR+ S R + +S SR R+ R SRS
Sbjct: 453 QDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR-------SRSS 505
Query: 194 SSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSS 239
S R S R RSP ++++ R + + E + S
Sbjct: 506 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 82.0 bits (201), Expect = 1e-15
Identities = 88/299 (29%), Positives = 124/299 (41%), Gaps = 37/299 (12%)
Query: 338 SPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKS--------SLVPSTARSSPMKGC 389
+PQ LE + R RE++ F S +E K + S S +RSS
Sbjct: 151 TPQAAAKELEEVM--KRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 208
Query: 390 SRSSSYASTRSSSHS---SRSPNPRASPRYTQSRSTSSEKR-SYSRSPSYSSKSGKRSPP 445
R S + RS SH+ SR + R S + RS S E+R S SRS S + R
Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 268
Query: 446 SRSSRSRRSPSYSRYSPSRERDP-----------KYSEKDSQQ-RERERARRRRRSYSPM 493
R + +ER+ K EKD ++ +E++R R R + +
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 328
Query: 494 RKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSR 553
R + ++ E R R + I R S + S+ +S SRS+SR R R
Sbjct: 329 RDKEKEKEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRSYNASRRSRSSSRERRRRR 385
Query: 554 SRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSR--------SRSRSRSRSQSRSYSSAD 604
SRS SR ++T SSRSPSP SR++ + S R R RS S SS D
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444
Score = 56.6 bits (135), Expect = 6e-08
Identities = 41/175 (23%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Query: 74 TNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSP--- 130
+ S R K + +R H+ S + S KK+ KS +++ RS S+S
Sbjct: 204 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263
Query: 131 ----VKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHK--KQSRSRPRKSHRHR 184
+K+K++ K ++ R K+R K+K RD++R K ++ + + R+ R +
Sbjct: 264 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREK 323
Query: 185 HHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSS 239
H R + E + R + RS E +K ++ R S ++SS
Sbjct: 324 EHE-KDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377
Score = 55.5 bits (132), Expect = 1e-07
Identities = 82/379 (21%), Positives = 133/379 (35%), Gaps = 40/379 (10%)
Query: 102 PPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKS 161
P + + K+ + K+ R + S+ + ++ + KS+++ K RS S R S SS KS
Sbjct: 148 PEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNER-KGGRSRSHTRSKSRSSSKS 206
Query: 162 -KRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRR- 219
RR + K +SRS R R + R RS+S + S R + RS + R+
Sbjct: 207 HSRRKRSQSKHRSRSHNRSRSRQKDRR---RSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263
Query: 220 -RHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS 278
R + + + + E + R + + RG + +
Sbjct: 264 TREKIKEKERVKEKDREKEREREKEREKE-----KERGKNKDRDKEREKDREKDKEKDRE 318
Query: 279 RGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSS 338
R R +E++ D R + +S+E++ D S T
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREK-----------DRSKEIDEKRKKDK-KSRTPPR 366
Query: 339 PQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAST 398
N + S R R SR SS P T+++ K SRS S S
Sbjct: 367 SYNASRRSRSSSRERRRRRSR-------------SSSRSPRTSKTIKRKS-SRSPSPRSR 412
Query: 399 RSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYS 458
S R + RSTS K S R K K S + + P S
Sbjct: 413 NKKDKKREKERDHISERRERERSTSMRKSSNDRDG--KEKLEKNSTSLKEKEHNKEPDSS 470
Query: 459 RYSPSRERDPKYSEKDSQQ 477
++D +E++ Q
Sbjct: 471 VSKEVDDKDAPRTEENKIQ 489
Score = 53.9 bits (128), Expect = 4e-07
Identities = 88/361 (24%), Positives = 130/361 (36%), Gaps = 70/361 (19%)
Query: 171 KQSRSRPRKSHRHRHH-RCPSRSQS-SESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKT 228
+ +S RK R R H R SRS S S SR +S+HR RS + R+ RR SK+
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRSKS 237
Query: 229 LCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSG 288
K +++ R SR RS D
Sbjct: 238 PHKKRSKSRERRK------------------------------------SRSRSHSRDKR 261
Query: 289 NDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLEN 348
DT + + + +EK + RE + G + + K +
Sbjct: 262 KDTREKIK-EKERVKEKDREK-------EREREKEREKEKERGKNKDRDKEREKDREKDK 313
Query: 349 LSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSP 408
R RE + E K+ R RS R SR+P
Sbjct: 314 EKDREREREKEHEKDRDKE----KEKEQDKEKEREK-----DRSKEIDEKRKKDKKSRTP 364
Query: 409 NPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDP 468
PR+ +SRS+S E+R R S SS R+ + +S RSPS + ++
Sbjct: 365 -PRSYNASRRSRSSSRERR---RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKRE 420
Query: 469 KYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSG 528
K + S++RERER+ R+S RD LE + TS +++ + P SS
Sbjct: 421 KERDHISERRERERSTSMRKS-----SNDRDGKEKLE-KNSTSLKEKE---HNKEPDSSV 471
Query: 529 S 529
S
Sbjct: 472 S 472
Score = 53.5 bits (127), Expect = 5e-07
Identities = 31/76 (40%), Positives = 44/76 (57%)
Query: 535 SWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSR 594
S+ S++ + +S R RSRS RS++R+SS S SR S+ RSRS +RSRSR +
Sbjct: 171 SFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 230
Query: 595 SQSRSYSSADSYSSTR 610
+ RS S S +R
Sbjct: 231 DRRRSKSPHKKRSKSR 246
Score = 53.1 bits (126), Expect = 7e-07
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 8/165 (4%)
Query: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
RE +R S S DK + K++ K+ R+K R ++ K K K +
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 144 ---RRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRH-HRCPSRSQSSESRP 199
R + K R K RD+++ K+Q + + R+ R + + + S + P
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 200 SSCESRHRGRSPEEGQKSRRRHSR----RCSKTLCKDSPEAQSSR 240
S + R RS ++ RR S R SKT+ + S + S R
Sbjct: 366 RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR 410
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/182 (25%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 78 ERDKTC-RELGATRGHSASHDKDLTPPPSSRGKKKK---------KKSTRKKRRRSSSYS 127
E+DK RE + H DK+ +++K +K +K R SY+
Sbjct: 310 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYN 369
Query: 128 PSPVKKKKKKSSKKHKRRRSFSKKR---------RHSSSSPKSKRRDEKRHKKQSRSRPR 178
S ++ + SS++ +RRRS S R R SS SP + R+ K+ KK+ + R
Sbjct: 370 AS---RRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN-KKDKKREKERDH 425
Query: 179 KSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQS 238
S R R S +SS R + S +E + ++ S + KD+P +
Sbjct: 426 ISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEE 485
Query: 239 SR 240
++
Sbjct: 486 NK 487
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 9/142 (6%)
Query: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK 143
R+ G +R H+ S + SS+ ++K+S K R RS + S S ++K ++ SK
Sbjct: 187 RKGGRSRSHTRSKSRS-----SSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRSKSPH 239
Query: 144 RRRSFSKKRR--HSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
++RS S++RR S S + KR+D + K+ K R R + E +
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 202 CESRHRGRSPEEGQKSRRRHSR 223
+ R + E+ ++ R R
Sbjct: 300 DRDKEREKDREKDKEKDRERER 321
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/190 (26%), Positives = 80/190 (42%), Gaps = 16/190 (8%)
Query: 68 ATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKK-RRRSSSY 126
A EP S ER K R TR S S K + S+ K + + R + R++
Sbjct: 176 AIEPESGKSNER-KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRR 234
Query: 127 SPSPVKKKKKKSSKKHKRRRSFSK-KRRHSSSSPKSKRR--DEKRHKKQSRSRPRKSHRH 183
S SP KK+ K ++ R RS S+ KR+ + K K R ++ R K++ R + R+ +
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294
Query: 184 R-------HHRCPSRSQSSE-SRPSSCESRH---RGRSPEEGQKSRRRHSRRCSKTLCKD 232
R R R + E R E H R + E+ Q + + SK + +
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 233 SPEAQSSRPP 242
+ + SR P
Sbjct: 355 RKKDKKSRTP 364
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 540 SSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRS------RS 593
S+ R RS S +RS+SRS +S +R S S +RSRSR + R RS RS
Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 243
Query: 594 RSQSRSYSSADSYSSTRR 611
+S+ R S + S+S +R
Sbjct: 244 KSRERRKSRSRSHSRDKR 261
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/166 (25%), Positives = 67/166 (40%), Gaps = 18/166 (10%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
ER+K RE RG + DK+ ++K K ++R R + K+K+K+
Sbjct: 284 EREKE-REKEKERGKNKDRDKE------REKDREKDKEKDREREREKEHEKDRDKEKEKE 336
Query: 138 SSKKHKRRRSFSK----KRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
K+ +R + SK KR+ S R + +S SR R+ R SRS
Sbjct: 337 QDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR-------SRSS 389
Query: 194 SSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSS 239
S R S R RSP ++++ R + + E + S
Sbjct: 390 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 79.3 bits (194), Expect = 9e-15
Identities = 78/260 (30%), Positives = 104/260 (40%), Gaps = 27/260 (10%)
Query: 378 PSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRS-------TSSEKRSYS 430
P + +G + R S RS +PR SPR ++SRS +SS R
Sbjct: 237 PRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELE 296
Query: 431 RSPS---YSSKSGKRSPPSRSSRS-------RRSPSYSRY-SPSRERDPKYSEKD---SQ 476
R ++ +R R SRS RRS S R+ S SR RD K +D +
Sbjct: 297 REKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER 356
Query: 477 QRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSW 536
++E ER RRR R Y R R+ R R R +
Sbjct: 357 EKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDK 416
Query: 537 YSSSSSRSASRSYSRSR---SRSRSR---RRSRTRTSSSSSSRSPSPGSRSRSRSRSRSR 590
S + SRS SR R SRSRSR +RSR+R+ SS +S RSRS S+
Sbjct: 417 RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQ 476
Query: 591 SRSRSQSRSYSSADSYSSTR 610
R+ S +S S S +
Sbjct: 477 GRTDSVEKSKKREHSPSKEK 496
Score = 62.4 bits (150), Expect = 1e-09
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 13/174 (7%)
Query: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRR-RSSSYSPSPVKKKKKKSSK-- 140
R R S S +D R ++++K++ R +RR R ++K+++ S+
Sbjct: 329 RSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRER 388
Query: 141 -KHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQS----S 195
K +R R ++++H + RD+KR K+ + R R R HR SRS++ S
Sbjct: 389 SKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS 448
Query: 196 ESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKD-----SPEAQSSRPPSQ 244
SR S+H+ S E+ K R S+ + ++ K SP + SR S+
Sbjct: 449 RSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSR 502
Score = 56.6 bits (135), Expect = 6e-08
Identities = 52/223 (23%), Positives = 83/223 (37%), Gaps = 7/223 (3%)
Query: 387 KGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPS 446
+G R S + R S S RS + + R +R R Y + G
Sbjct: 323 RGLERRRSRSRERHRSRS-RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKE 381
Query: 447 RSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEA 506
R RS E+ K + D + R+ +R ++ + +S R R R S +
Sbjct: 382 RERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRS 441
Query: 507 R----RITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRS 562
R R S K ++ + S S + S S+ S S+ +SR+RS
Sbjct: 442 RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRS 501
Query: 563 RTRTSSSSSSRSPSPGSRSRSRSRSRSRS-RSRSQSRSYSSAD 604
R++ S S S +S R RS+S SQ + + + D
Sbjct: 502 RSKERSHKRDHSDSK-DQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 55.8 bits (133), Expect = 1e-07
Identities = 55/194 (28%), Positives = 85/194 (43%), Gaps = 40/194 (20%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
+RD+ RE RG D D RG +++K+ R + R S V++KK K
Sbjct: 351 DRDRE-REKENERGRRRDRDYD-----KERGNEREKERERSRERSKEQRSRGEVEEKKHK 404
Query: 138 --------------SSKKHKRRRSFSKKRRHSSSS------PKSKRRDEK---RHKKQSR 174
S K+ K RS S++R+H S S +S+ R ++ +HK +S+
Sbjct: 405 EDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESK 464
Query: 175 SRPRKSHRH-RHHRCPS--RSQSSESRPSSCESRHRGRSPEEGQK--------SRRRHSR 223
+ K R R S +S+ E PS +SR R RS E K +H R
Sbjct: 465 EKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDR 524
Query: 224 RCSKTLCKDSPEAQ 237
R S+++ ++S E Q
Sbjct: 525 RRSQSIEQESQEKQ 538
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/164 (29%), Positives = 70/164 (42%), Gaps = 22/164 (13%)
Query: 76 SWERDKTCRELGATRGHSASHDKD-LTPPPSSRGKKKKKKSTRKKRR----RSSSYSPSP 130
S ER K R G DKD R KK+KK +R + R RS S S +
Sbjct: 385 SRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNA 444
Query: 131 VKKK----KKKSSKKHKRRRSFSKKRRHSSSS------PKSKRRDEKRHKKQSRSRPRKS 180
K+ K+KSSK + S KR S S KSK+R+ K++SR R R
Sbjct: 445 GKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK 504
Query: 181 HR-HRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSR 223
R H+ S+ QS + R R +S E+ + ++ ++
Sbjct: 505 ERSHKRDHSDSKDQSDK------HDRRRSQSIEQESQEKQHKNK 542
Score = 50.4 bits (119), Expect = 5e-06
Identities = 72/341 (21%), Positives = 124/341 (36%), Gaps = 59/341 (17%)
Query: 90 RGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFS 149
R S S + L+P S R + + +S ++ SSS+ ++K+++ ++ + R
Sbjct: 257 RRRSRSPRRSLSPRRSPR--RSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKE 314
Query: 150 KKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGR 209
++R S +RR R + +SRSR R R R R + +E RGR
Sbjct: 315 RRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENE----------RGR 364
Query: 210 SPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFT 269
+ R + R + ++ + Q SR +
Sbjct: 365 RRDRDYDKERGNEREKERERSRERSKEQRSRGEVEE-----------------------K 401
Query: 270 KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSD 329
K R R + DS + +RSR +E+ S+SR N+G S
Sbjct: 402 KHKEDKDDRRHRDDKRDS--------KKEKKHSRSRSRERKH----RSRSRSRNAGKRSR 449
Query: 330 SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
S + +S +N+ S R G Q + KK PS +S
Sbjct: 450 SRSKEKSSKHKNES------KEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSR----- 498
Query: 390 SRSSSYASTRSSSHS-SRSPNPRASPRYTQSRSTSSEKRSY 429
RS S + HS S+ + + R +QS S+++ +
Sbjct: 499 KRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539
Score = 49.7 bits (117), Expect = 8e-06
Identities = 84/370 (22%), Positives = 131/370 (35%), Gaps = 47/370 (12%)
Query: 146 RSF-SKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCES 204
RSF +K S+ P+ +K +Q ++RPRK + + E
Sbjct: 205 RSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVE-------- 256
Query: 205 RHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSA 264
R R RSP RR R S++ + E S + L+
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHR---EGHGSSSFDRELER-------------EKE 300
Query: 265 ADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNS 324
+ A R RS+ D G + S + +RSR +++ + RE +
Sbjct: 301 RQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKEN 360
Query: 325 GNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSS 384
+ + E S+ + SRG E E K
Sbjct: 361 ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRG------EVEEKKHKEDKDDRRHRD 414
Query: 385 PMKGCSRSSSYASTRSSS--HSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKR 442
+ + ++ +RS H SRS + A R SRS S EK S ++ S KS KR
Sbjct: 415 DKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR---SRSRSKEKSSKHKNES-KEKSNKR 470
Query: 443 SPPSRSSRSRRSPSYSR-----YSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRR 497
S RS R+ S + +SPS+E+ K S S++R +R + S RR
Sbjct: 471 S---RSGSQGRTDSVEKSKKREHSPSKEKSRKRSR--SKERSHKRDHSDSKDQSDKHDRR 525
Query: 498 RDSPSHLEAR 507
R E++
Sbjct: 526 RSQSIEQESQ 535
Score = 49.3 bits (116), Expect = 1e-05
Identities = 78/362 (21%), Positives = 120/362 (33%), Gaps = 63/362 (17%)
Query: 108 GKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEK 167
GK+ ++ R RR S SP + + S + R RS ++ SSS + R+++
Sbjct: 244 GKEGAEEIDRHVERRRSR---SPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE 300
Query: 168 RHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSK 227
R + + ++ R+ R R S + E R S RHR RS +K RR R
Sbjct: 301 RQRLEREAKEREKERRRSR---SIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR--- 354
Query: 228 TLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDS 287
E ++ R + Y RG + SR RS+E S
Sbjct: 355 -----EREKENERGRRRDRD---YDKERG------------NEREKERERSRERSKEQRS 394
Query: 288 GNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLE 347
+ + R +K SK + +S + S + S +N G
Sbjct: 395 RGEVEEKKHKEDKDDRRHRDDKRD-----SKKEKKHSRSRSRERKHRSRSRSRNAG---- 445
Query: 348 NLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRS 407
K S S +SS K S+ S +RS S
Sbjct: 446 -------------------------KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD 480
Query: 408 PNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERD 467
++ R S KRS S+ S+ S RRS S + S ++
Sbjct: 481 SVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHK 540
Query: 468 PK 469
K
Sbjct: 541 NK 542
Score = 40.8 bits (94), Expect = 0.004
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 20/121 (16%)
Query: 74 TNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKK 133
+ S R++ R +R ++ + + SS+ K + K+ + K+ R S V+K
Sbjct: 426 SRSRSRERKHRSRSRSR-NAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEK 484
Query: 134 KKKKS---SKKHKRRRSFSK----KRRHSSSSPKSKRRD------------EKRHKKQSR 174
KK+ SK+ R+RS SK KR HS S +S + D EK+HK +
Sbjct: 485 SKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Query: 175 S 175
+
Sbjct: 545 T 545
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 79.3 bits (194), Expect = 9e-15
Identities = 67/204 (32%), Positives = 92/204 (45%), Gaps = 14/204 (6%)
Query: 417 TQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQ 476
T+ + EK S R SP R+S+ S S SR SRER K + +
Sbjct: 6 TERDGLAPEKTSPDRDKKKEQSEVSVSP--RASKHHYSRSRSR---SRERKRKSDNEGRK 60
Query: 477 QRERERARRRRRSYSPMRKRRR---------DSPSHLEARRITSARKRPIPYYRPSPSSS 527
R R R++ RR S + ++ + S R+ S+ + R SS
Sbjct: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
Query: 528 GSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRS 587
S + S RS SR +SRSRSR R++SR+R+ SRS S + R RSRS
Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
Query: 588 RSRSRSRSQSRSYSSADSYSSTRR 611
RSRSR R ++RS S S S R+
Sbjct: 181 RSRSRHRHRTRSRSRTRSRSRDRK 204
Score = 79.0 bits (193), Expect = 1e-14
Identities = 66/214 (30%), Positives = 91/214 (42%), Gaps = 30/214 (14%)
Query: 399 RSSSHSSRSPNPRASPR-YTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSY 457
+ S S +PRAS Y++SRS S E++ S ++ K SRS RR S
Sbjct: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKS-----DNEGRKHRSRSRSKEGRRHESK 76
Query: 458 SRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPI 517
+ S + + ++ S + RER +++ R S R S +R
Sbjct: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR-- 134
Query: 518 PYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSP 577
SRS R SRSRSR R + RSR+R S SRS
Sbjct: 135 ----------------------HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 172
Query: 578 GSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
R RSRSRSRSR R R++SRS + + S +R
Sbjct: 173 KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 206
Score = 68.9 bits (167), Expect = 1e-11
Identities = 56/159 (35%), Positives = 73/159 (45%), Gaps = 17/159 (10%)
Query: 95 SHDKDLTPPPSSRGKKKKKKSTR-KKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRR 153
S DK S K+ S + ++R SS K+K++KSS+ RS S++RR
Sbjct: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134
Query: 154 HSSSS---PKSKRRDEKRHKKQSRSRPRKS----HRHRHHRCPSRSQSSESRPSSCESRH 206
H S S KS+ R +R K +SRSR RK R R R SRS+S SR
Sbjct: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS 194
Query: 207 RGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245
R RS +K R RR S++L SR PS P
Sbjct: 195 RTRSRSRDRKKRIEKPRRFSRSL---------SRTPSPP 224
Score = 62.8 bits (151), Expect = 9e-10
Identities = 75/267 (28%), Positives = 107/267 (40%), Gaps = 43/267 (16%)
Query: 347 ENLSP--TSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHS 404
+ L+P TS R+ + QS K S +RS K S H
Sbjct: 9 DGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKS------DNEGRKHR 62
Query: 405 SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPS------RSSRSRRSPSYS 458
SRS + ++ +S+ K +SS G+ S R R R S
Sbjct: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
Query: 459 R-YSPSRERDPKY---SEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITS-AR 513
R +S SR R+ ++ S + + R R R R++ RS S RK+ R S S RRI S +R
Sbjct: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR-SRSRERKRRIRSRSR 181
Query: 514 KRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSR 573
R S R+ SRS +RSRSR R +R + R S S SR
Sbjct: 182 SR----------------------SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 219
Query: 574 SPSPGS-RSRSRSRSRSRSRSRSQSRS 599
+PSP R R+ + + +R R+
Sbjct: 220 TPSPPPFRGRNTAMDAQEALARRLERA 246
Score = 57.0 bits (136), Expect = 5e-08
Identities = 46/157 (29%), Positives = 70/157 (44%), Gaps = 18/157 (11%)
Query: 100 LTPPPSSRGKKKKKKSTR-------KKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKK- 151
L P +S + KKK+ + K S S S S +K+K + + R RS SK+
Sbjct: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG 70
Query: 152 RRHSSSSPKSKRRDEKRH--KKQSRSRPRK--------SHRHRHHRCPSRSQSSESRPSS 201
RRH S SK+ + H K+ S + R+ RH+ S S SR S
Sbjct: 71 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 130
Query: 202 CESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQS 238
E RHR RS E + R R+ S++ ++ +++S
Sbjct: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 167
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 21/186 (11%)
Query: 60 SEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKK 119
S+K + L + G + +R + R+ R HS SR ++++ +S ++
Sbjct: 95 SDKGRERLNSSENGEDRHKRKE--RKSSRGRSHSR-----------SRSRERRHRSRSRE 141
Query: 120 RRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRK 179
R++S S S K + + +K R RS +KRR S +S+ R RH+ +SRSR R
Sbjct: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS---RSRSRSRHRHRTRSRSRTRS 198
Query: 180 SHRHRHHRCP-----SRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSP 234
R R R SRS S P R+ +E R +++ + K+
Sbjct: 199 RSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 258
Query: 235 EAQSSR 240
E Q +
Sbjct: 259 EKQKQQ 264
Score = 43.1 bits (100), Expect = 7e-04
Identities = 70/328 (21%), Positives = 120/328 (36%), Gaps = 81/328 (24%)
Query: 161 SKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRR 220
S RD+K+ + + PR S +HH SRS+S E + S + RS +SR +
Sbjct: 17 SPDRDKKKEQSEVSVSPRAS---KHHYSRSRSRSRERKRKSDNEGRKHRS-----RSRSK 68
Query: 221 HSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRG 280
RR +S + S + S+ + S +G R
Sbjct: 69 EGRR------HESKDKSSKKHKSEEHNDKEHSSDKG----------------------RE 100
Query: 281 RSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQ 340
R ++G D ++S RS + + S+SRE
Sbjct: 101 RLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSR-------------- 146
Query: 341 NKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRS 400
SR RE + +S E +K S S R ++ SRS S R+
Sbjct: 147 ------------SRSRERKKSRSRSRE----RKKSRSRSRERKRRIRSRSRSRSRHRHRT 190
Query: 401 SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRY 460
S S ++RS S +++ P S+S R+P R R + ++
Sbjct: 191 RSRS-------------RTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQE 237
Query: 461 SPSRERDPKYSEKDSQQRERERARRRRR 488
+ +R + ++K +QRE+E ++++
Sbjct: 238 ALARRLE--RAKKLQEQREKEMVEKQKQ 263
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 79.0 bits (193), Expect = 1e-14
Identities = 77/242 (31%), Positives = 107/242 (44%), Gaps = 19/242 (7%)
Query: 362 QSPCLECAEVKKSSLVPSTARSSPMK------GCSRSSSYASTRSSSHSSRSPNPRASPR 415
+SP +E + S P+ R + G ++ A+ +++ + P A P+
Sbjct: 302 RSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQ 361
Query: 416 Y---TQSRSTSSEKRSYSRSPSYSSK--SGKRSPPSRSSRSRRSPSY---SRYSPSRERD 467
R+ S+ +RS S S S S+ S RS SSRSRR Y R++ SR R
Sbjct: 362 PGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRS 421
Query: 468 PKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEA-----RRITSARKRPIPYYRP 522
S S++ R R+R RR S R R S S RR + +R YR
Sbjct: 422 WSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRR 481
Query: 523 SPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSR 582
SS+ S S S S S SRS +RSRS S S +SR+R+ S S S SPSP
Sbjct: 482 GGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKL 541
Query: 583 SR 584
+R
Sbjct: 542 TR 543
Score = 77.8 bits (190), Expect = 3e-14
Identities = 88/275 (32%), Positives = 113/275 (41%), Gaps = 35/275 (12%)
Query: 356 RESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPR 415
R+ R F+ L ++ S R SP + S S+ S SRSP P +
Sbjct: 269 RQRREFREKRLRGRKISPPSYA---RRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEK 325
Query: 416 YTQSRSTSSEKRSYSRSPSYSSKSGKRS-----PP---------SRSSRSRRSPSYSRYS 461
T S + + + ++ SG + PP + S+R R S S S S
Sbjct: 326 ITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSS 385
Query: 462 PSRERDPKYSEKDSQQRER--------ERARRRRRSYSPMRKR-RRDSPSHLEARRITSA 512
SR + S + S + R AR R RS+S R R RR S S RR +
Sbjct: 386 ASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGG 445
Query: 513 RKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSS 572
R Y SP+ G RS SRS+S R R R +S S SS
Sbjct: 446 GSRDGHRYSRSPARRGGYGPRR--------RSRSRSHSGDRYRRGGRGLRHHSSSRSRSS 497
Query: 573 RSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYS 607
S SP SRSRS +RSRS S S SQSRS S + S S
Sbjct: 498 WSLSP-SRSRSLTRSRSHSPSPSQSRSRSRSRSQS 531
Score = 72.4 bits (176), Expect = 1e-12
Identities = 94/295 (31%), Positives = 126/295 (42%), Gaps = 33/295 (11%)
Query: 293 SPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPT 352
SPPS + + K SPS S+SR + T T + + G E +
Sbjct: 285 SPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFIT--SFGGSDEEAAAA 342
Query: 353 SRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRA 412
+ + G + K P +P + S A RSSS SS S R
Sbjct: 343 AAAAAASGVTTG--------KPPAPPQPGGPAPGRNAS-----ARRRSSSSSSSSSASRT 389
Query: 413 SPRYTQSRSTSSEKRS--YSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKY 470
S + SRS+S +R Y RS ++ +S RS SRSRR YS SR R ++
Sbjct: 390 SSSRSSSRSSSRSRRGGGYYRSGRHA-RSRSRSWSRSRSRSRR------YSRSRSRGRRH 442
Query: 471 SEKDSQQRER-ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPS-SSG 528
S S+ R R+ RR Y P R+ R S S RR R + ++ S S SS
Sbjct: 443 SGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRR----GGRGLRHHSSSRSRSSW 498
Query: 529 SLS---STSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSR 580
SLS S S S S S S S+S SRSRSRS+S S R + + SP+ G +
Sbjct: 499 SLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEK 553
Score = 70.5 bits (171), Expect = 4e-12
Identities = 120/474 (25%), Positives = 178/474 (37%), Gaps = 51/474 (10%)
Query: 132 KKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRD--EKRHKKQSRSRPRKSHRHRHHRCP 189
K K++ + KH + +K +S + +RR+ EKR + + S P + R P
Sbjct: 241 KDKEEAEAIKHAKALE-EEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDP 299
Query: 190 SRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQML 249
+ SES S ESR R RSP G R + T S E ++ +
Sbjct: 300 YKRSPSES---SSESRSRSRSPTPG-----REEKITFITSFGGSDEEAAAAAAAA----- 346
Query: 250 GYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEK 309
+A GV TG A + P R S S + +SS +++TSS+RS +
Sbjct: 347 ---AASGVTTGKPPAPP---QPGGP-APGRNASARRRSSSSSSSSSASRTSSSRSSSR-- 397
Query: 310 GSPSGGLSKSRELNSGNTSDSGN---SFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCL 366
S SR G SG S + S +++ SRGR G S
Sbjct: 398 -------SSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGS--- 447
Query: 367 ECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK 426
+ + S P+ + SRS S++ R R ++ SRS SS
Sbjct: 448 --RDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGG------RGLRHHSSSRSRSSWS 499
Query: 427 RSYSRSPSYS-SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARR 485
S SRS S + S+S SP SRSR SP+RE+ + + + + ++
Sbjct: 500 LSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEP 559
Query: 486 RRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA 545
+ K + L+ R + A R + + R+
Sbjct: 560 AAGKETGAAKPKLTPQEKLKLR-MQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAM 618
Query: 546 SRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRS 599
+R R + R S SRSPSP SR S SR RSRS+SRS
Sbjct: 619 ARKIRMKERERREKEREEWERQYSRQSRSPSP---RYSREYSSSRRRSRSRSRS 669
Score = 70.1 bits (170), Expect = 6e-12
Identities = 70/204 (34%), Positives = 93/204 (45%), Gaps = 19/204 (9%)
Query: 418 QSRSTSSEKRSYSRSPSYSSK---SGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKD 474
+ ++ S +RS + + K K SPPS + R SP+Y Y +R P S +
Sbjct: 257 EEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRD--SPTYDPY----KRSPSESSSE 310
Query: 475 SQQRERERARRRRR------SYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSG 528
S+ R R R S+ + + + A +T+ K P P P+
Sbjct: 311 SRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTG-KPPAPPQPGGPAPGR 369
Query: 529 SLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSR 588
+ S+ SSSSS SASR+ S SRS SRS RSR S R SRS SRSRSR
Sbjct: 370 NASARRRSSSSSSSSSASRT-SSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
Query: 589 SR--SRSRSQSRSYSSADSYSSTR 610
SR SRSRS+ R +S S R
Sbjct: 429 SRRYSRSRSRGRRHSGGGSRDGHR 452
Score = 69.3 bits (168), Expect = 1e-11
Identities = 87/353 (24%), Positives = 127/353 (35%), Gaps = 59/353 (16%)
Query: 103 PPSSRGKKKKKKSTRKKRRRSSSYSPSPVK----KKKKKSSKKHKRRRSFSKKRRHSSSS 158
PP G + ++ ++R SSS S S + + +SS + +R + + RH+ S
Sbjct: 359 PPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSR 418
Query: 159 PKSKRRDEKRHKKQSRSRPRKSHR--------HRHHRCPSRSQSSESRPSSCESRHRGRS 210
+S R R ++ SRSR R HR+ R P+R R S H G
Sbjct: 419 SRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDR 478
Query: 211 PEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ-----PLQMLGYLSARGVITGSGSAA 265
G + R HS S++ SP S S+ P Q +R A
Sbjct: 479 YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAR 538
Query: 266 DLFTK-TASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNS 324
+ T+ ASP + + E +G +T + T + + L + LN
Sbjct: 539 EKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLK----------LRMQKALNR 588
Query: 325 GNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSS 384
+D K A E + R+ R + + AR
Sbjct: 589 QFKAD------------KKAAQEKMIQQEHERQER--------------EDELRAMARKI 622
Query: 385 PMKGCSRSSSYAS--TRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSY 435
MK R R S SRSP+PR S Y+ SR S RS SRSP Y
Sbjct: 623 RMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS---RSRSRSPHY 672
Score = 68.6 bits (166), Expect = 2e-11
Identities = 82/237 (34%), Positives = 100/237 (42%), Gaps = 39/237 (16%)
Query: 406 RSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR---RSPSYSRYSP 462
RS R R + R SY+R S + KRSP SS SR RSP+ P
Sbjct: 266 RSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPT-----P 320
Query: 463 SRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPS---------HLEARRITSAR 513
RE + E A + S + + +P + ARR +S+
Sbjct: 321 GREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSS 380
Query: 514 KRPIPYYRPSPSSSGSLSSTSS------WYSSSSSRSASRSYSRSRSRSR--SRRRSRTR 565
R S S S S SS+ S + S +RS SRS+SRSRSRSR SR RSR R
Sbjct: 381 SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGR 440
Query: 566 TSSSSSSR-----SPSP------GSRSRSRSRSRSRSRSRSQSRS---YSSADSYSS 608
S SR S SP G R RSRSRS S R R R +SS+ S SS
Sbjct: 441 RHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSS 497
Score = 61.2 bits (147), Expect = 3e-09
Identities = 111/467 (23%), Positives = 171/467 (36%), Gaps = 69/467 (14%)
Query: 105 SSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRR 164
S R +++++ R+KR R SP ++ + +KR S S S S + R
Sbjct: 263 SGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGR 322
Query: 165 DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRR-HSR 223
+EK S + + ++ P+ + G +P +RRR S
Sbjct: 323 EEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPA--PPQPGGPAPGRNASARRRSSSS 380
Query: 224 RCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQ 283
S + + S SSR S+ + GY SG A +++ S SR RS+
Sbjct: 381 SSSSSASRTSSSRSSSRSSSRSRRGGGYYR-------SGRHARSRSRSWS---RSRSRSR 430
Query: 284 EYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKG 343
Y S +RSRG+ +SG S G+ + + SP +G
Sbjct: 431 RY--------------SRSRSRGRR--------------HSGGGSRDGHRY-SRSPARRG 461
Query: 344 AMLENLSPTSRG----RESRGFQSPCLECAEVKKS--SLVPSTARS-SPMKGCSRSSSYA 396
SR R RG + + +S SL PS +RS + + S S S +
Sbjct: 462 GYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQS 521
Query: 397 STRSSSHS-SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSP 455
+RS S S S SP+P + S + ++ P+ ++G P +
Sbjct: 522 RSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLR 581
Query: 456 SYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKR 515
+ + D K +++ Q+E ER R + RK R E R R+
Sbjct: 582 MQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQ- 640
Query: 516 PIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRS 562
S S S S SR YS SR RSRSR RS
Sbjct: 641 ------------------YSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
Score = 35.4 bits (80), Expect = 0.15
Identities = 35/177 (19%), Positives = 67/177 (37%), Gaps = 8/177 (4%)
Query: 75 NSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKS-------TRKKRRRSSSYS 127
+S R ++ L +R S + + +P PS + + +S R+K R ++ S
Sbjct: 489 HSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAA-S 547
Query: 128 PSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187
P+ +K KK K + K ++ R K + ++ + H
Sbjct: 548 PAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHE 607
Query: 188 CPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244
R + + R R +E ++ R++SR+ + S E SSR S+
Sbjct: 608 RQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSR 664
Score = 32.7 bits (73), Expect = 1.0
Identities = 36/171 (21%), Positives = 71/171 (41%), Gaps = 25/171 (14%)
Query: 44 RTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTC-RELGATRGHSASHDKDLTP 102
R+ ++ P+ EKL + A+ +G + + +E GA + LTP
Sbjct: 522 RSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAK-------PKLTP 574
Query: 103 PPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSK 162
+ K + +K+ ++ + + + +++ + ++ R+ ++K R + K
Sbjct: 575 --QEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREK 632
Query: 163 RRDE--KRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSP 211
R+E +++ +QSRS PS S E S SR R RSP
Sbjct: 633 EREEWERQYSRQSRS-------------PSPRYSREYSSSRRRSRSRSRSP 670
Score = 31.2 bits (69), Expect = 2.9
Identities = 18/78 (23%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Query: 109 KKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSK-RRDEK 167
++K + +++ R K + K+ ++ K R + ++ S SP + R+
Sbjct: 598 QEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYS 657
Query: 168 RHKKQSRSRPRKSHRHRH 185
+++SRSR R H +RH
Sbjct: 658 SSRRRSRSRSRSPH-YRH 674
Score = 30.4 bits (67), Expect = 5.0
Identities = 15/48 (31%), Positives = 27/48 (56%)
Query: 107 RGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRH 154
R +++K++ +++ S SPSP ++ SS++ R RS S RH
Sbjct: 627 RERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYRH 674
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 79.0 bits (193), Expect = 1e-14
Identities = 94/349 (26%), Positives = 147/349 (42%), Gaps = 25/349 (7%)
Query: 270 KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSD 329
K + L+ R + D N+ P+ TS + + K G S+S +SG++S
Sbjct: 461 KEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSS 520
Query: 330 SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
+ + +TSS + + S + R S SP K S +RS +K
Sbjct: 521 NSRTSSTSSTVSSSSYS---SSSGSSRTSSRSSSP--------KRKKRHSRSRSPTIKAR 569
Query: 390 -SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSK-SGKRSPPSR 447
SRS SY S R S+R+ + R +R++ +R +RSPS + S RS R
Sbjct: 570 RSRSRSY-SRRIKIESNRA-RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRR 627
Query: 448 SSRSRRSPSYSRYSPSRER---DPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHL 504
++R+ RS S R +R + + +E+ER + R RS RK++ D
Sbjct: 628 TNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKK-DKERER 686
Query: 505 EARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS----RSYSRSRSRSRSRR 560
E + +KR ++ S S + S S S S R SR S+ + +
Sbjct: 687 EQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTK 746
Query: 561 RSRTRTSSSSSSR--SPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYS 607
S+ + S SS R S SPGS +++ SRSRS +S S S
Sbjct: 747 DSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKAS 795
Score = 69.7 bits (169), Expect = 7e-12
Identities = 118/562 (20%), Positives = 189/562 (33%), Gaps = 81/562 (14%)
Query: 103 PPSSRGKKKKKKSTRKKRRRSS-----SYSPSPVKKKKKKS----------SKKHKRRRS 147
PP+ ++++ S+ + R+RS P + K+++ + ++++
Sbjct: 191 PPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKK 250
Query: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRH---------HRCPSRSQSSESR 198
K+R S SK+ + + PR R + + S +R
Sbjct: 251 LEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTR 310
Query: 199 PSSCESRHRGRSPEEGQKSRRRHSRRCSKTL----------------CKDSPEAQSSRPP 242
S + PE ++ + +K L KD+ + P
Sbjct: 311 SPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPA 370
Query: 243 SQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPS-TQTSS 301
Q L SA +TG G G D +D S S T
Sbjct: 371 KQ----LAQSSALASLTGLGGLGGY------------GSGDSEDERSDRGSESSDTDDEE 414
Query: 302 ARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAML---ENLSPTSRGRES 358
R R ++K K ++L + T + + +N RE+
Sbjct: 415 LRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREA 474
Query: 359 RGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQ 418
G + KK + +T+ P K +RS S SS S + + T
Sbjct: 475 DG------DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS 528
Query: 419 SRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR---------RSPSYSRYSPSRERDPK 469
S +SS S S S SS+S R SRSR RS SYSR +
Sbjct: 529 STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRAR 588
Query: 470 YSEKDSQQRERER-ARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSG 528
+D ++ R R RRR+ SP R+RRR S S RR A + R G
Sbjct: 589 VKIRDRRRSNRNSIERERRRNRSPSRERRR-SRSRSRDRRTNRASRSRSRDRRKIDDQRG 647
Query: 529 SLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR---RSRTRTSSSSSSRSPSPGSRSRSRS 585
+LS S + ++ R RSRS + R+ + R R + + S
Sbjct: 648 NLSGNSHKH-KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
Query: 586 RSRSRSRSRSQSRSYSSADSYS 607
+ R R R++S + S S
Sbjct: 707 QDDRLKRKRESERTFSRSGSIS 728
Score = 57.8 bits (138), Expect = 3e-08
Identities = 63/210 (30%), Positives = 83/210 (39%), Gaps = 50/210 (23%)
Query: 402 SHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYS 461
+ R+PN S + + EK RS S SS SG S SR+S + + S S YS
Sbjct: 480 NEKKRTPNETTS--VLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS 537
Query: 462 PSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYR 521
S +R RS SP RK+R H +R T +R
Sbjct: 538 SSSGS----------------SRTSSRSSSPKRKKR-----HSRSRSPTIKARR------ 570
Query: 522 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 581
S SRS SR +R+R + R R R++ +S R R+
Sbjct: 571 ------------------SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR---RN 609
Query: 582 RSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
RS SR R RSRSRS+ R + A S R
Sbjct: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDR 639
Score = 56.6 bits (135), Expect = 6e-08
Identities = 81/352 (23%), Positives = 128/352 (36%), Gaps = 53/352 (15%)
Query: 110 KKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRH 169
KK+ K K+ R S S S ++S S S SS S+ KR
Sbjct: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
Query: 170 KKQSRSR-PRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEG-QKSRRRH-----S 222
K+ SRSR P R R SR ES + + R R RS ++ RRR+
Sbjct: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE 615
Query: 223 RRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRS 282
RR S++ +D ++SR S+ + + RG ++G+ +G +
Sbjct: 616 RRRSRSRSRDRRTNRASRSRSRDRRKID--DQRGNLSGNSHK-------------HKGEA 660
Query: 283 QEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS--FTTSSPQ 340
+E + + RSR +K + RE + F SS
Sbjct: 661 KEQERKKE------------RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD 708
Query: 341 NKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRS 400
++ R RES S + S+ R + +S++ S +
Sbjct: 709 DR---------LKRKRESERTFS--------RSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Query: 401 SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR 452
S S + SP ++ + K S SRS S +SGK++ S+SR
Sbjct: 752 SGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSR 803
Score = 55.5 bits (132), Expect = 1e-07
Identities = 57/255 (22%), Positives = 100/255 (39%), Gaps = 15/255 (5%)
Query: 74 TNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKK 133
T+S + ++ G S + + +P R + + + + +R RS SYS ++
Sbjct: 524 TSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYS----RR 579
Query: 134 KKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
K +S++ + R + R+S + + R R +++SRSR R +R R SR +
Sbjct: 580 IKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDR 639
Query: 194 ----SSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQML 249
S +H+G + E+ +K R S+++ KD + R Q +
Sbjct: 640 RKIDDQRGNLSGNSHKHKGEAKEQERKKER------SRSIDKDRKKKDKEREREQDKRKE 693
Query: 250 GYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEK 309
S L K S T SR S S S ++++ S+ +
Sbjct: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK-KHS 752
Query: 310 GSPSGGLSKSRELNS 324
GS S G S S S
Sbjct: 753 GSDSSGRSSSESPGS 767
Score = 52.0 bits (123), Expect = 2e-06
Identities = 65/244 (26%), Positives = 96/244 (39%), Gaps = 36/244 (14%)
Query: 381 ARSSPMKGCSRSSSYASTRS----SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYS 436
A +P K ++SS+ AS + S S R ++S T E+ +
Sbjct: 365 ATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR------ 418
Query: 437 SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER------ERARRRRRSY 490
R ++ + + + K E++ QQ ER E + + S
Sbjct: 419 ------------IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSL 466
Query: 491 SPMRKRRRDSPSHLEARRI---TSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR 547
S + R D E +R T++ P ++ S S +SS SSSS+ S
Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526
Query: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSR-SRSRSRSRSRSRSQSRSYSSADSY 606
+ S S S S +RTSS RS SP + R SRSRS + RS+SRSYS
Sbjct: 527 TSSTVSSSSYSSSSGSSRTSS----RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKI 582
Query: 607 SSTR 610
S R
Sbjct: 583 ESNR 586
Score = 50.1 bits (118), Expect = 6e-06
Identities = 43/157 (27%), Positives = 72/157 (45%), Gaps = 12/157 (7%)
Query: 72 LGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKK-KKKSTRKKRRRSSSYSPSP 130
L NS + +E + S S DKD R +++ K+K +K+ + +S
Sbjct: 649 LSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD 708
Query: 131 VKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSH--RHRHHRC 188
+ K+K+ S+ R+FS R S S K R D ++ K+S ++ K H R
Sbjct: 709 DRLKRKRESE-----RTFS---RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRS 760
Query: 189 PSRSQSSESRPSSCESRH-RGRSPEEGQKSRRRHSRR 224
S S S + + +H R RS E+ Q+S ++ SR+
Sbjct: 761 SSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRK 797
Score = 43.5 bits (101), Expect = 6e-04
Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
E ++T G+ HD S+ K KK S RSSS SP K+KK K
Sbjct: 716 ESERTFSRSGSISVKIIRHDSRQDSKKSTT-KDSKKHSGSDSSGRSSSESPGSSKEKKAK 774
Query: 138 SSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSR 176
K H R RS K +R S ++ ++HK +SRSR
Sbjct: 775 KPK-HSRSRSVEKSQR-------SGKKASRKHKSKSRSR 805
Score = 38.5 bits (88), Expect = 0.018
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 105 SSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKH-----KRRRSFSKKRRHSSSSP 159
S + K+K+ + + RS S S ++ ++ SKK K+ R SS SP
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
Query: 160 KSKRRDEKRHKKQSRSRP-RKSHRH-----RHHRCPSRSQ 193
S + + + K SRSR KS R R H+ SRS+
Sbjct: 766 GSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 79.0 bits (193), Expect = 1e-14
Identities = 70/175 (40%), Positives = 85/175 (48%), Gaps = 22/175 (12%)
Query: 444 PPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ------RERERARRRRRSYSPMRKRR 497
PP S + + YSP P+ SE Q R + RARRR+ +++R
Sbjct: 678 PPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKG-----QEKR 732
Query: 498 RDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSW-YSSSSSRSASRSYSRSRSRS 556
PS +R + R S S S S SS SS YS S SRS SRSYSRSRSRS
Sbjct: 733 NSGPSRSRSRSKSRGR---------SSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRS 783
Query: 557 RSRRRS-RTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
RSR RS R+R+ S S SRS S R RSRSRS + S +SA +R
Sbjct: 784 RSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
Score = 58.2 bits (139), Expect = 2e-08
Identities = 54/142 (38%), Positives = 67/142 (47%), Gaps = 8/142 (5%)
Query: 411 RASPRYTQSRSTSSEKRSYSRSPSY---SSKSGKRSPPSRSSRSR-RSPSYSR-YSPSRE 465
RA R Q + S RS SRS S SS+S RS S S SR RS S SR YS SR
Sbjct: 722 RARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS 781
Query: 466 RDPKYSEKDSQQRERERARRRRRSYSPMRKR--RRDSPSHLEARRITSARKRPIPYYRPS 523
R S + S+ R R ++R R +SYSP R+R R SP+ + + S PIP R
Sbjct: 782 RSRSRS-RSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG 840
Query: 524 PSSSGSLSSTSSWYSSSSSRSA 545
+ G +S S A
Sbjct: 841 EENKGHQMLVKMGWSGSGGLGA 862
Score = 52.8 bits (125), Expect = 9e-07
Identities = 55/148 (37%), Positives = 66/148 (44%), Gaps = 14/148 (9%)
Query: 443 SPPSRSSRSRRSPSYSRY-------SPSRERDPKYSEKDSQQRERERARRRRRSYSPMRK 495
SPPS R R S + + + R R K EK + R R+R + R S R
Sbjct: 695 SPPSHD-RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRS 753
Query: 496 RRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSR 555
R S S R S + Y S S S S S +S S S SRS S+SYS R R
Sbjct: 754 NSRSSKSSGSYSR--SRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGR-R 810
Query: 556 SRSRRRSRTRTSSS---SSSRSPSPGSR 580
RSR RS T SS+ S+S P P SR
Sbjct: 811 RRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
Score = 50.4 bits (119), Expect = 5e-06
Identities = 35/69 (50%), Positives = 41/69 (59%), Gaps = 3/69 (4%)
Query: 543 RSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
R + SRSRSR +SR R+SS S+SRS S S SRSRSRS SRS SRS S
Sbjct: 726 RKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS---SKSSGSYSRSRSRSCSRSYSRSRSR 782
Query: 603 ADSYSSTRR 611
+ S S + R
Sbjct: 783 SRSRSRSSR 791
Score = 49.3 bits (116), Expect = 1e-05
Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 17/133 (12%)
Query: 110 KKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRH 169
+ K ++ R+K + + PS + + SK R S S R SS S+ R
Sbjct: 718 RAKMRARRRKGQEKRNSGPS----RSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCS 773
Query: 170 KKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTL 229
+ SRSR R R R R SRSQS SR + SP RRR SR S T
Sbjct: 774 RSYSRSRSRSRSRSRSSRSRSRSQS--------RSRSKSYSP-----GRRRRSRSRSPTP 820
Query: 230 CKDSPEAQSSRPP 242
+ +S PP
Sbjct: 821 PSSAGLGSNSAPP 833
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Query: 97 DKDLTPPPSSRGKKKKK-KSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHS 155
+K + P SR + K + +S+ + RSS S S + + + S+ + R RS S+ R S
Sbjct: 730 EKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRS 789
Query: 156 SSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESR 205
S S +S+ + R K S R R+S S S S P +SR
Sbjct: 790 SRS-RSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/95 (41%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHS---SRSPNPRASPRYTQSRSTSSEKRS 428
+K + PS +RS K RSSS +++RSS S SRS + S Y++SRS S +
Sbjct: 730 EKRNSGPSRSRSRS-KSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR 788
Query: 429 YSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPS 463
SRS S S+S RS R RRS S S PS
Sbjct: 789 SSRSRS-RSQSRSRSKSYSPGRRRRSRSRSPTPPS 822
Score = 42.7 bits (99), Expect = 0.001
Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Query: 340 QNKGAMLENLSPT-SRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRS--SSYA 396
+ KG N P+ SR R +S + KSS S +RS + CSRS S +
Sbjct: 725 RRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRS---RSCSRSYSRSRS 781
Query: 397 STRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSG---KRSPPSRSSR 450
+RS S SSRS + S ++S S +RS SRSP+ S +G +PP SR
Sbjct: 782 RSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/147 (29%), Positives = 55/147 (37%), Gaps = 33/147 (22%)
Query: 139 SKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198
+K RRR +KR S R + +S+SR R S R S S SR
Sbjct: 719 AKMRARRRKGQEKRNSGPS----------RSRSRSKSRGRSSSRSNSRSSKSSGSYSRSR 768
Query: 199 PSSC-----ESRHRGRSPEEGQKSR-RRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYL 252
SC SR R RS +SR R SR SK+ SR P+ P
Sbjct: 769 SRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPP------- 821
Query: 253 SARGVITGSGSAADLFTKTASPLTTSR 279
S+A L + +A P+ SR
Sbjct: 822 ----------SSAGLGSNSAPPIPDSR 838
Score = 40.0 bits (92), Expect = 0.006
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 107 RGKKKKKKSTRKKRRRSSSY--SPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRR 164
+G++K+ + R RS S S S + KSS + R RS S R +S S +S+ R
Sbjct: 727 KGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSR 786
Query: 165 DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198
+SRSR + R + + P R + S SR
Sbjct: 787 SRS---SRSRSRSQSRSRSKSY-SPGRRRRSRSR 816
Score = 33.1 bits (74), Expect = 0.77
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 58 GPSEKLGQHLATEPLGTNSWERDKTC-RELGATRGHSASHDKDLTPPPSSRGKKKKKKST 116
G S +++ G+ S R ++C R +R S S + S+ + + K +
Sbjct: 747 GRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYS 806
Query: 117 RKKRRRSSSYSPSP 130
+RRRS S SP+P
Sbjct: 807 PGRRRRSRSRSPTP 820
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 79.0 bits (193), Expect = 1e-14
Identities = 94/349 (26%), Positives = 147/349 (42%), Gaps = 25/349 (7%)
Query: 270 KTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSD 329
K + L+ R + D N+ P+ TS + + K G S+S +SG++S
Sbjct: 461 KEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSS 520
Query: 330 SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGC 389
+ + +TSS + + S + R S SP K S +RS +K
Sbjct: 521 NSRTSSTSSTVSSSSYS---SSSGSSRTSSRSSSP--------KRKKRHSRSRSPTIKAR 569
Query: 390 -SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSK-SGKRSPPSR 447
SRS SY S R S+R+ + R +R++ +R +RSPS + S RS R
Sbjct: 570 RSRSRSY-SRRIKIESNRA-RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRR 627
Query: 448 SSRSRRSPSYSRYSPSRER---DPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHL 504
++R+ RS S R +R + + +E+ER + R RS RK++ D
Sbjct: 628 TNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKK-DKERER 686
Query: 505 EARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS----RSYSRSRSRSRSRR 560
E + +KR ++ S S + S S S S R SR S+ + +
Sbjct: 687 EQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTK 746
Query: 561 RSRTRTSSSSSSR--SPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYS 607
S+ + S SS R S SPGS +++ SRSRS +S S S
Sbjct: 747 DSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKAS 795
Score = 69.7 bits (169), Expect = 7e-12
Identities = 118/562 (20%), Positives = 189/562 (33%), Gaps = 81/562 (14%)
Query: 103 PPSSRGKKKKKKSTRKKRRRSS-----SYSPSPVKKKKKKS----------SKKHKRRRS 147
PP+ ++++ S+ + R+RS P + K+++ + ++++
Sbjct: 191 PPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKK 250
Query: 148 FSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRH---------HRCPSRSQSSESR 198
K+R S SK+ + + PR R + + S +R
Sbjct: 251 LEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTR 310
Query: 199 PSSCESRHRGRSPEEGQKSRRRHSRRCSKTL----------------CKDSPEAQSSRPP 242
S + PE ++ + +K L KD+ + P
Sbjct: 311 SPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPA 370
Query: 243 SQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPS-TQTSS 301
Q L SA +TG G G D +D S S T
Sbjct: 371 KQ----LAQSSALASLTGLGGLGGY------------GSGDSEDERSDRGSESSDTDDEE 414
Query: 302 ARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAML---ENLSPTSRGRES 358
R R ++K K ++L + T + + +N RE+
Sbjct: 415 LRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREA 474
Query: 359 RGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQ 418
G + KK + +T+ P K +RS S SS S + + T
Sbjct: 475 DG------DVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS 528
Query: 419 SRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR---------RSPSYSRYSPSRERDPK 469
S +SS S S S SS+S R SRSR RS SYSR +
Sbjct: 529 STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRAR 588
Query: 470 YSEKDSQQRERER-ARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSG 528
+D ++ R R RRR+ SP R+RRR S S RR A + R G
Sbjct: 589 VKIRDRRRSNRNSIERERRRNRSPSRERRR-SRSRSRDRRTNRASRSRSRDRRKIDDQRG 647
Query: 529 SLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR---RSRTRTSSSSSSRSPSPGSRSRSRS 585
+LS S + ++ R RSRS + R+ + R R + + S
Sbjct: 648 NLSGNSHKH-KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706
Query: 586 RSRSRSRSRSQSRSYSSADSYS 607
+ R R R++S + S S
Sbjct: 707 QDDRLKRKRESERTFSRSGSIS 728
Score = 57.8 bits (138), Expect = 3e-08
Identities = 63/210 (30%), Positives = 83/210 (39%), Gaps = 50/210 (23%)
Query: 402 SHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYS 461
+ R+PN S + + EK RS S SS SG S SR+S + + S S YS
Sbjct: 480 NEKKRTPNETTS--VLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYS 537
Query: 462 PSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYR 521
S +R RS SP RK+R H +R T +R
Sbjct: 538 SSSGS----------------SRTSSRSSSPKRKKR-----HSRSRSPTIKARR------ 570
Query: 522 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 581
S SRS SR +R+R + R R R++ +S R R+
Sbjct: 571 ------------------SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR---RN 609
Query: 582 RSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
RS SR R RSRSRS+ R + A S R
Sbjct: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDR 639
Score = 56.6 bits (135), Expect = 6e-08
Identities = 81/352 (23%), Positives = 128/352 (36%), Gaps = 53/352 (15%)
Query: 110 KKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRH 169
KK+ K K+ R S S S ++S S S SS S+ KR
Sbjct: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
Query: 170 KKQSRSR-PRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEG-QKSRRRH-----S 222
K+ SRSR P R R SR ES + + R R RS ++ RRR+
Sbjct: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE 615
Query: 223 RRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRS 282
RR S++ +D ++SR S+ + + RG ++G+ +G +
Sbjct: 616 RRRSRSRSRDRRTNRASRSRSRDRRKID--DQRGNLSGNSHK-------------HKGEA 660
Query: 283 QEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS--FTTSSPQ 340
+E + + RSR +K + RE + F SS
Sbjct: 661 KEQERKKE------------RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD 708
Query: 341 NKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRS 400
++ R RES S + S+ R + +S++ S +
Sbjct: 709 DR---------LKRKRESERTFS--------RSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Query: 401 SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR 452
S S + SP ++ + K S SRS S +SGK++ S+SR
Sbjct: 752 SGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSR 803
Score = 55.5 bits (132), Expect = 1e-07
Identities = 57/255 (22%), Positives = 100/255 (39%), Gaps = 15/255 (5%)
Query: 74 TNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKK 133
T+S + ++ G S + + +P R + + + + +R RS SYS ++
Sbjct: 524 TSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYS----RR 579
Query: 134 KKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
K +S++ + R + R+S + + R R +++SRSR R +R R SR +
Sbjct: 580 IKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDR 639
Query: 194 ----SSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQML 249
S +H+G + E+ +K R S+++ KD + R Q +
Sbjct: 640 RKIDDQRGNLSGNSHKHKGEAKEQERKKER------SRSIDKDRKKKDKEREREQDKRKE 693
Query: 250 GYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEK 309
S L K S T SR S S S ++++ S+ +
Sbjct: 694 KQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK-KHS 752
Query: 310 GSPSGGLSKSRELNS 324
GS S G S S S
Sbjct: 753 GSDSSGRSSSESPGS 767
Score = 52.0 bits (123), Expect = 2e-06
Identities = 65/244 (26%), Positives = 96/244 (39%), Gaps = 36/244 (14%)
Query: 381 ARSSPMKGCSRSSSYASTRS----SSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYS 436
A +P K ++SS+ AS + S S R ++S T E+ +
Sbjct: 365 ATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR------ 418
Query: 437 SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER------ERARRRRRSY 490
R ++ + + + K E++ QQ ER E + + S
Sbjct: 419 ------------IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSL 466
Query: 491 SPMRKRRRDSPSHLEARRI---TSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR 547
S + R D E +R T++ P ++ S S +SS SSSS+ S
Sbjct: 467 SLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSS 526
Query: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSR-SRSRSRSRSRSRSQSRSYSSADSY 606
+ S S S S +RTSS RS SP + R SRSRS + RS+SRSYS
Sbjct: 527 TSSTVSSSSYSSSSGSSRTSS----RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKI 582
Query: 607 SSTR 610
S R
Sbjct: 583 ESNR 586
Score = 50.1 bits (118), Expect = 6e-06
Identities = 43/157 (27%), Positives = 72/157 (45%), Gaps = 12/157 (7%)
Query: 72 LGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKK-KKKSTRKKRRRSSSYSPSP 130
L NS + +E + S S DKD R +++ K+K +K+ + +S
Sbjct: 649 LSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD 708
Query: 131 VKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSH--RHRHHRC 188
+ K+K+ S+ R+FS R S S K R D ++ K+S ++ K H R
Sbjct: 709 DRLKRKRESE-----RTFS---RSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRS 760
Query: 189 PSRSQSSESRPSSCESRH-RGRSPEEGQKSRRRHSRR 224
S S S + + +H R RS E+ Q+S ++ SR+
Sbjct: 761 SSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRK 797
Score = 43.5 bits (101), Expect = 6e-04
Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
E ++T G+ HD S+ K KK S RSSS SP K+KK K
Sbjct: 716 ESERTFSRSGSISVKIIRHDSRQDSKKSTT-KDSKKHSGSDSSGRSSSESPGSSKEKKAK 774
Query: 138 SSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSR 176
K H R RS K +R S ++ ++HK +SRSR
Sbjct: 775 KPK-HSRSRSVEKSQR-------SGKKASRKHKSKSRSR 805
Score = 38.5 bits (88), Expect = 0.018
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 105 SSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKH-----KRRRSFSKKRRHSSSSP 159
S + K+K+ + + RS S S ++ ++ SKK K+ R SS SP
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
Query: 160 KSKRRDEKRHKKQSRSRP-RKSHRH-----RHHRCPSRSQ 193
S + + + K SRSR KS R R H+ SRS+
Sbjct: 766 GSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 76.6 bits (187), Expect = 6e-14
Identities = 74/198 (37%), Positives = 100/198 (50%), Gaps = 33/198 (16%)
Query: 415 RYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKD 474
R + + +S +RSYS S S S+S +RS SRSRRS SR R S+
Sbjct: 177 RLIEDKPRTSHRRSYSGSRS-RSRSRRRS----RSRSRRS--------SRSRSRSISK-- 221
Query: 475 SQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTS 534
S+ R R R++ R RS S RK R S S ++ R S S S S +
Sbjct: 222 SRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDR---------------GSHSHSRSRSK 266
Query: 535 SWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSR--SRSRSR 592
Y S SRS SRS + + + +SR+R+ S S+S P P S++RS S R+ SR
Sbjct: 267 DEYEKSRSRSRSRS-PKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSR 325
Query: 593 SRSQSRSYSSADSYSSTR 610
SRS+SRS S + S SS+R
Sbjct: 326 SRSRSRSKSRSRSRSSSR 343
Score = 73.2 bits (178), Expect = 7e-13
Identities = 62/176 (35%), Positives = 83/176 (47%), Gaps = 18/176 (10%)
Query: 390 SRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSS 449
S SY+ +RS S S R R+ RS+ S RS S+S S S K SR S
Sbjct: 186 SHRRSYSGSRSRSRSRRRSRSRS------RRSSRSRSRSISKSRSRSRSRSKGRSRSR-S 238
Query: 450 RSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRI 509
+ R+S S S+ P +R + + E E++R R RS SP + D S +R
Sbjct: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRS- 297
Query: 510 TSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTR 565
S P+P PS + S+ S R+ SRS SRSRS+SRSR RS +R
Sbjct: 298 QSRSNSPLPV---PPSKARSV-------SPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Score = 69.3 bits (168), Expect = 1e-11
Identities = 55/126 (43%), Positives = 68/126 (53%), Gaps = 9/126 (7%)
Query: 488 RSYSPMRKRRRDS--PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSA 545
RSYS M KR D + + R I +P +R S S S S S S SRS
Sbjct: 154 RSYSDM-KRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSR-----SRRRSRSR 207
Query: 546 SRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYS-SAD 604
SR SRSRSRS S+ RSR+R+ S SRS S G +SRS+S+S+ +S S S S S S D
Sbjct: 208 SRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD 267
Query: 605 SYSSTR 610
Y +R
Sbjct: 268 EYEKSR 273
Score = 58.9 bits (141), Expect = 1e-08
Identities = 57/179 (31%), Positives = 82/179 (45%), Gaps = 24/179 (13%)
Query: 145 RRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQS-SESRPSSCE 203
RRS+S R S +S+RR R ++ SRSR R + R R SRS+ S SR +
Sbjct: 188 RRSYSGSRSRS----RSRRRSRSRSRRSSRSRSRSISKSR-SRSRSRSKGRSRSRSKGRK 242
Query: 204 SRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVI-TGSG 262
SR + +S + + HSR SK + S SR P + + +G I + S
Sbjct: 243 SRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKE--------NGKGDIKSKSR 294
Query: 263 SAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRE 321
S + + + P+ S+ RS S PP TS +RSR + K S S S SR+
Sbjct: 295 SRSQSRSNSPLPVPPSKARS--------VSPPPKRATSRSRSRSRSK-SRSRSRSSSRD 344
Score = 58.2 bits (139), Expect = 2e-08
Identities = 47/147 (31%), Positives = 60/147 (40%), Gaps = 17/147 (11%)
Query: 102 PPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKS 161
P S R +S + RRRS S S + + + SK R RS SK R S S +
Sbjct: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
Query: 162 KRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEG------Q 215
R K K R H H R S+ + +SR SR R RSP+E
Sbjct: 243 SRSKSKSKPKSDRGS------HSHSRSRSKDEYEKSR-----SRSRSRSPKENGKGDIKS 291
Query: 216 KSRRRHSRRCSKTLCKDSPEAQSSRPP 242
KSR R R + L +A+S PP
Sbjct: 292 KSRSRSQSRSNSPLPVPPSKARSVSPP 318
Score = 57.8 bits (138), Expect = 3e-08
Identities = 38/68 (55%), Positives = 44/68 (64%), Gaps = 11/68 (16%)
Query: 544 SASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSA 603
S RSYS SRSRSRSRRRSR+R+ SS RSRSRS S+SRSRS+SRS +
Sbjct: 186 SHRRSYSGSRSRSRSRRRSRSRSRRSS-----------RSRSRSISKSRSRSRSRSKGRS 234
Query: 604 DSYSSTRR 611
S S R+
Sbjct: 235 RSRSKGRK 242
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/156 (31%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 73 GTNSWERDKTCRELGATRGHSASHDKDLTPPPS-SRGKKKKKKSTRKKRRRSSSYSPSPV 131
G+ S R + R +R S S + ++ S SR + K + +R K R+S S S S
Sbjct: 193 GSRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS-- 249
Query: 132 KKKKKKSSKKHKRRRS---FSKKR-RHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187
K K + S H R RS + K R R S SPK + + + K +SRS+ R +
Sbjct: 250 KPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVP- 308
Query: 188 CPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSR 223
PS+++S P SR R RS + + R SR
Sbjct: 309 -PSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Score = 49.7 bits (117), Expect = 8e-06
Identities = 46/143 (32%), Positives = 62/143 (43%), Gaps = 10/143 (6%)
Query: 353 SRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRA 412
SR R S +S + + + S +RS SRS S + +S S R+
Sbjct: 206 SRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRS 265
Query: 413 SPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERD----P 468
Y +SRS RS SRSP + K +S SRS RS S PS+ R P
Sbjct: 266 KDEYEKSRS-----RSRSRSPKENGKGDIKS-KSRSRSQSRSNSPLPVPPSKARSVSPPP 319
Query: 469 KYSEKDSQQRERERARRRRRSYS 491
K + S+ R R ++R R RS S
Sbjct: 320 KRATSRSRSRSRSKSRSRSRSSS 342
Score = 48.9 bits (115), Expect = 1e-05
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 7/156 (4%)
Query: 78 ERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKK 137
++ +T + S S + + S R + + +S K R RS S S + + K
Sbjct: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR-SRSRSK 239
Query: 138 SSKKHKRRRSFSKKRRHSSSSPKSKRRDE-KRHKKQSRSRPRKSHRHRHHRCPSRSQSSE 196
K + +S K R S S +S+ +DE ++ + +SRSR K + + SRS+ S+
Sbjct: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSR-SQ 298
Query: 197 SRPSS----CESRHRGRSPEEGQKSRRRHSRRCSKT 228
SR +S S+ R SP + + R SR SK+
Sbjct: 299 SRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKS 334
Score = 45.1 bits (105), Expect = 2e-04
Identities = 55/178 (30%), Positives = 74/178 (41%), Gaps = 25/178 (14%)
Query: 291 TSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLS 350
TS S S +RSR + + S+SR + + S + S ++KG
Sbjct: 185 TSHRRSYSGSRSRSRSRRRSR-----SRSRRSSRSRSRSISKSRSRSRSRSKGRSRSR-- 237
Query: 351 PTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSS-YASTRSSSHSSRSPN 409
S+GR+SR KS P + R S SRS Y +RS S S RSP
Sbjct: 238 --SKGRKSRS------------KSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRS-RSPK 282
Query: 410 PRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSR-RSPSYSRYSPSRER 466
+ S+ RS S P SK+ SPP + + SR RS S S+ S SR R
Sbjct: 283 ENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK-SRSRSR 339
Score = 36.2 bits (82), Expect = 0.091
Identities = 41/157 (26%), Positives = 60/157 (38%), Gaps = 22/157 (14%)
Query: 278 SRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTS 337
SR S+ S S S RSR + KG S SKS+ + + S +
Sbjct: 208 SRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD 267
Query: 338 SPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYAS 397
+ + + SP G+ + S +RS + SRS+S
Sbjct: 268 EYEKSRSRSRSRSPKENGKGD------------------IKSKSRS---RSQSRSNSPLP 306
Query: 398 TRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPS 434
S S SP P+ + ++SRS S+ RS SRS S
Sbjct: 307 VPPSKARSVSPPPKRATSRSRSRS-RSKSRSRSRSSS 342
Score = 35.0 bits (79), Expect = 0.20
Identities = 34/131 (25%), Positives = 52/131 (39%), Gaps = 10/131 (7%)
Query: 275 LTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPS---GGLSKSRELNSGNTSDSG 331
++ SR RS+ G S ++ +SR + K P G S SR + S
Sbjct: 219 ISKSRSRSRSRSKGRSRS-----RSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSR 273
Query: 332 NSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSR 391
+ + SP+ G ++ SR R SP +S P +S + SR
Sbjct: 274 SRSRSRSPKENGK--GDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSR 331
Query: 392 SSSYASTRSSS 402
S S + +RSSS
Sbjct: 332 SKSRSRSRSSS 342
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 76.3 bits (186), Expect = 8e-14
Identities = 117/453 (25%), Positives = 172/453 (37%), Gaps = 57/453 (12%)
Query: 180 SHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSS 239
S RH + S S +PSS R +RH + SK + +PEA S
Sbjct: 4 SERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASL 63
Query: 240 RPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS-------RGRSQEYDSGNDTS 292
+PL +S+ A L + S + R ++ D
Sbjct: 64 GTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLL 123
Query: 293 SPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFT--TSSPQNKGAMLENLS 350
T+ ++ + GS +S S + ++ T D G + +SS +++ + L
Sbjct: 124 KAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHK-- 181
Query: 351 PTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNP 410
+ R+ R +S + ++ + P SY + S SRSP+
Sbjct: 182 --EKTRKERELKSGHKDRSKSHRKRETPK--------------SYKTVDSPKRRSRSPHR 225
Query: 411 RASPRYTQSRSTS--SEKRSYSRSPSYSSKSG-----KRSPPSRSSRSRRSPSYSRYSPS 463
+ S Q S S S + Y SPS S S K+SP S S R SP Y
Sbjct: 226 KWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPY------ 279
Query: 464 RERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPS 523
++P S S R RR+RS SP +RR S R + + + P PY R
Sbjct: 280 --KEP--SAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYE----RSGSYSGRSPSPYGRRR 331
Query: 524 PSSSGSLSSTSSWYS------SSSSRSASRSYSR-SRSRSRSRR-RSRTRTSSSSSSRSP 575
SSS LS S S S SRS S +YSR S S S+ +R SR+R SS S R P
Sbjct: 332 -SSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLP 390
Query: 576 SPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608
S SR + + + + +S S
Sbjct: 391 LNSSLGAELSRKKKERAAAAAAAKMDGKESKGS 423
Score = 69.7 bits (169), Expect = 7e-12
Identities = 98/432 (22%), Positives = 164/432 (37%), Gaps = 62/432 (14%)
Query: 160 KSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRR 219
K RR+ + RS + H+HRHH+ +++ + E S K R
Sbjct: 90 KLDRRENDERRGSDRSD--RLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRI 147
Query: 220 RHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSR 279
S + S D +AQ ++ S+ S + + + K+ +
Sbjct: 148 SGSSKRSNEETDDYGKAQVAKSSSKE-------SRSSKLHKEKTRKERELKSGHKDRSKS 200
Query: 280 GRSQEYDSGNDTSSPPSTQTSSARSR----GQEKGSPSG-GLSKSRELNSGNTSDSGNSF 334
R +E T P ++ S + ++ SPSG + +L+ + S N
Sbjct: 201 HRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYD 260
Query: 335 TTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSS 394
+ + +++SP +E +QS S P + R + SR S
Sbjct: 261 SYKKSPGSTSRRQSVSPPY--KEPSAYQS--------STRSPSPYSRRQRSVSPYSRRRS 310
Query: 395 YASTRSSSHSSRSPNPRASPRYTQSRSTSS--EKRSYSRSPSYSSKSGKRSPPSRSSRSR 452
+ RS S+S RSP+P Y + RS+S KRS SRSP S KS K SRS
Sbjct: 311 SSYERSGSYSGRSPSP-----YGRRRSSSPFLSKRSLSRSPLPSRKSMK----SRS---- 357
Query: 453 RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMR------------KRRRDS 500
RSP+YSR+S S + ++R +R R S SP+R +++++
Sbjct: 358 RSPAYSRHSSSHSK-----------KKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKER 406
Query: 501 PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR 560
+ A ++ + P + P +S + S S RS S + +
Sbjct: 407 AAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVT 466
Query: 561 RSRTRTSSSSSS 572
T +SS +
Sbjct: 467 HLNTEVKNSSDT 478
Score = 68.6 bits (166), Expect = 2e-11
Identities = 102/376 (27%), Positives = 146/376 (38%), Gaps = 69/376 (18%)
Query: 300 SSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS---FTTSSPQNKGAMLENLSPTSRGR 356
+S R G++ GS GG S + + +SG S + + ++K +++ +
Sbjct: 3 NSERHGGKKDGS--GGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA 60
Query: 357 ESRGFQ-SPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSS-HSSRSPNPRASP 414
S G P +E ++ S S + + S RS H R R S
Sbjct: 61 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR 120
Query: 415 RYTQSRSTSSEKRSYSRSPSYSSKS----------------GKRSPPSRSSRSRRSPSYS 458
+++ T EK S S S K GK SS+ RS
Sbjct: 121 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH 180
Query: 459 RYSPSRERDPKYSEKDSQQRERERARRR---------RRSYSPMRK-----RRRDSPSHL 504
+ +ER+ K KD + R+R + RRS SP RK ++ DSPS
Sbjct: 181 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 505 E---------ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSS-RSASRSYSRSRS 554
+R TS+ Y+ SP S+ S S Y S+ +S++RS S
Sbjct: 241 SYGQDYDLSPSRSHTSSN---YDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSR 297
Query: 555 RSRS------RRRSRTRTSSSSSSRSPSPGSRSRSRS-----RSRSRS--------RSRS 595
R RS RR S S S S RSPSP R RS S RS SRS +SRS
Sbjct: 298 RQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRS 357
Query: 596 QSRSYSSADSYSSTRR 611
+S +YS S S ++
Sbjct: 358 RSPAYSRHSSSHSKKK 373
Score = 51.6 bits (122), Expect = 2e-06
Identities = 99/394 (25%), Positives = 152/394 (38%), Gaps = 78/394 (19%)
Query: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRD 165
SR K K++ ++K + SS S S + S + ++ + K + SSS +S R
Sbjct: 119 SRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKES--RS 176
Query: 166 EKRHKKQSRSRPR-------KSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSR 218
K HK+++R +S HR P ++ +S + R RSP
Sbjct: 177 SKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDS------PKRRSRSP------- 223
Query: 219 RRHSRRCSKTLCKDSPEAQS-----SRPPSQPLQMLGYLSARGVITGSGSAADLFTKTAS 273
H + + DSP S PS+ + + S D + K S
Sbjct: 224 --HRKWSDSSKQDDSPSGASYGQDYDLSPSR--------------SHTSSNYDSYKK--S 265
Query: 274 PLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS 333
P +TSR +S ++ ST++ S SR Q SP S SG S
Sbjct: 266 PGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSG-------S 318
Query: 334 FTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSS 393
++ SP SP R R S SP L + +S P +R S MK SRS
Sbjct: 319 YSGRSP----------SPYGRRRSS----SPFLSKRSLSRS---PLPSRKS-MKSRSRSP 360
Query: 394 SYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRR 453
+Y S SSSHS + R+S R S S S + + S K+ + ++ ++
Sbjct: 361 AY-SRHSSSHSKKK---RSSSRSRHS-SISPVRLPLNSSLGAELSRKKKERAAAAAAAKM 415
Query: 454 SPSYSRYSP---SRERDPKYSEKDSQQRERERAR 484
S+ SP R+ + KDS ++ R
Sbjct: 416 DGKESKGSPVFLPRKENSSVEAKDSGLESKKLPR 449
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 26/179 (14%)
Query: 85 ELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKK--RRRSSSYSPSPVKKKKKKSSKKH 142
+L +R H++S+ P S +++ K+ +SS+ SPSP ++++S +
Sbjct: 247 DLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPY-SRRQRSVSPY 305
Query: 143 KRRRSFSKKRRHS----SSSPKSKRRD-----EKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
RRRS S +R S S SP +RR KR +S RKS + R R P+ S+
Sbjct: 306 SRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSR-SRSPAYSR 364
Query: 194 SSES----RPSSCESRHRGRSPEE--------GQKSRRRHSRRCSKTLCK-DSPEAQSS 239
S S + SS SRH SP + SR++ R + K D E++ S
Sbjct: 365 HSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGS 423
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 76.3 bits (186), Expect = 8e-14
Identities = 117/453 (25%), Positives = 172/453 (37%), Gaps = 57/453 (12%)
Query: 180 SHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSS 239
S RH + S S +PSS R +RH + SK + +PEA S
Sbjct: 4 SERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEAASL 63
Query: 240 RPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTS-------RGRSQEYDSGNDTS 292
+PL +S+ A L + S + R ++ D
Sbjct: 64 GTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLL 123
Query: 293 SPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFT--TSSPQNKGAMLENLS 350
T+ ++ + GS +S S + ++ T D G + +SS +++ + L
Sbjct: 124 KAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHK-- 181
Query: 351 PTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNP 410
+ R+ R +S + ++ + P SY + S SRSP+
Sbjct: 182 --EKTRKERELKSGHKDRSKSHRKRETPK--------------SYKTVDSPKRRSRSPHR 225
Query: 411 RASPRYTQSRSTS--SEKRSYSRSPSYSSKSG-----KRSPPSRSSRSRRSPSYSRYSPS 463
+ S Q S S S + Y SPS S S K+SP S S R SP Y
Sbjct: 226 KWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPY------ 279
Query: 464 RERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPS 523
++P S S R RR+RS SP +RR S R + + + P PY R
Sbjct: 280 --KEP--SAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYE----RSGSYSGRSPSPYGRRR 331
Query: 524 PSSSGSLSSTSSWYS------SSSSRSASRSYSR-SRSRSRSRR-RSRTRTSSSSSSRSP 575
SSS LS S S S SRS S +YSR S S S+ +R SR+R SS S R P
Sbjct: 332 -SSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLP 390
Query: 576 SPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608
S SR + + + + +S S
Sbjct: 391 LNSSLGAELSRKKKERAAAAAAAKMDGKESKGS 423
Score = 69.7 bits (169), Expect = 7e-12
Identities = 98/432 (22%), Positives = 164/432 (37%), Gaps = 62/432 (14%)
Query: 160 KSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRR 219
K RR+ + RS + H+HRHH+ +++ + E S K R
Sbjct: 90 KLDRRENDERRGSDRSD--RLHKHRHHQHRRSRDLLKAKQTEKEKSQEVSSKSGSMKDRI 147
Query: 220 RHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSR 279
S + S D +AQ ++ S+ S + + + K+ +
Sbjct: 148 SGSSKRSNEETDDYGKAQVAKSSSKE-------SRSSKLHKEKTRKERELKSGHKDRSKS 200
Query: 280 GRSQEYDSGNDTSSPPSTQTSSARSR----GQEKGSPSG-GLSKSRELNSGNTSDSGNSF 334
R +E T P ++ S + ++ SPSG + +L+ + S N
Sbjct: 201 HRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYD 260
Query: 335 TTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSS 394
+ + +++SP +E +QS S P + R + SR S
Sbjct: 261 SYKKSPGSTSRRQSVSPPY--KEPSAYQS--------STRSPSPYSRRQRSVSPYSRRRS 310
Query: 395 YASTRSSSHSSRSPNPRASPRYTQSRSTSS--EKRSYSRSPSYSSKSGKRSPPSRSSRSR 452
+ RS S+S RSP+P Y + RS+S KRS SRSP S KS K SRS
Sbjct: 311 SSYERSGSYSGRSPSP-----YGRRRSSSPFLSKRSLSRSPLPSRKSMK----SRS---- 357
Query: 453 RSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMR------------KRRRDS 500
RSP+YSR+S S + ++R +R R S SP+R +++++
Sbjct: 358 RSPAYSRHSSSHSK-----------KKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKER 406
Query: 501 PSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRR 560
+ A ++ + P + P +S + S S RS S + +
Sbjct: 407 AAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVT 466
Query: 561 RSRTRTSSSSSS 572
T +SS +
Sbjct: 467 HLNTEVKNSSDT 478
Score = 68.6 bits (166), Expect = 2e-11
Identities = 102/376 (27%), Positives = 146/376 (38%), Gaps = 69/376 (18%)
Query: 300 SSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS---FTTSSPQNKGAMLENLSPTSRGR 356
+S R G++ GS GG S + + +SG S + + ++K +++ +
Sbjct: 3 NSERHGGKKDGS--GGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA 60
Query: 357 ESRGFQ-SPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSS-HSSRSPNPRASP 414
S G P +E ++ S S + + S RS H R R S
Sbjct: 61 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR 120
Query: 415 RYTQSRSTSSEKRSYSRSPSYSSKS----------------GKRSPPSRSSRSRRSPSYS 458
+++ T EK S S S K GK SS+ RS
Sbjct: 121 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH 180
Query: 459 RYSPSRERDPKYSEKDSQQRERERARRR---------RRSYSPMRK-----RRRDSPSHL 504
+ +ER+ K KD + R+R + RRS SP RK ++ DSPS
Sbjct: 181 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 505 E---------ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSS-RSASRSYSRSRS 554
+R TS+ Y+ SP S+ S S Y S+ +S++RS S
Sbjct: 241 SYGQDYDLSPSRSHTSSN---YDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSR 297
Query: 555 RSRS------RRRSRTRTSSSSSSRSPSPGSRSRSRS-----RSRSRS--------RSRS 595
R RS RR S S S S RSPSP R RS S RS SRS +SRS
Sbjct: 298 RQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRS 357
Query: 596 QSRSYSSADSYSSTRR 611
+S +YS S S ++
Sbjct: 358 RSPAYSRHSSSHSKKK 373
Score = 51.6 bits (122), Expect = 2e-06
Identities = 99/394 (25%), Positives = 152/394 (38%), Gaps = 78/394 (19%)
Query: 106 SRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRD 165
SR K K++ ++K + SS S S + S + ++ + K + SSS +S R
Sbjct: 119 SRDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKES--RS 176
Query: 166 EKRHKKQSRSRPR-------KSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSR 218
K HK+++R +S HR P ++ +S + R RSP
Sbjct: 177 SKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDS------PKRRSRSP------- 223
Query: 219 RRHSRRCSKTLCKDSPEAQS-----SRPPSQPLQMLGYLSARGVITGSGSAADLFTKTAS 273
H + + DSP S PS+ + + S D + K S
Sbjct: 224 --HRKWSDSSKQDDSPSGASYGQDYDLSPSR--------------SHTSSNYDSYKK--S 265
Query: 274 PLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNS 333
P +TSR +S ++ ST++ S SR Q SP S SG S
Sbjct: 266 PGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSG-------S 318
Query: 334 FTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSS 393
++ SP SP R R S SP L + +S P +R S MK SRS
Sbjct: 319 YSGRSP----------SPYGRRRSS----SPFLSKRSLSRS---PLPSRKS-MKSRSRSP 360
Query: 394 SYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRR 453
+Y S SSSHS + R+S R S S S + + S K+ + ++ ++
Sbjct: 361 AY-SRHSSSHSKKK---RSSSRSRHS-SISPVRLPLNSSLGAELSRKKKERAAAAAAAKM 415
Query: 454 SPSYSRYSP---SRERDPKYSEKDSQQRERERAR 484
S+ SP R+ + KDS ++ R
Sbjct: 416 DGKESKGSPVFLPRKENSSVEAKDSGLESKKLPR 449
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 26/179 (14%)
Query: 85 ELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKK--RRRSSSYSPSPVKKKKKKSSKKH 142
+L +R H++S+ P S +++ K+ +SS+ SPSP ++++S +
Sbjct: 247 DLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPY-SRRQRSVSPY 305
Query: 143 KRRRSFSKKRRHS----SSSPKSKRRD-----EKRHKKQSRSRPRKSHRHRHHRCPSRSQ 193
RRRS S +R S S SP +RR KR +S RKS + R R P+ S+
Sbjct: 306 SRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSR-SRSPAYSR 364
Query: 194 SSES----RPSSCESRHRGRSPEE--------GQKSRRRHSRRCSKTLCK-DSPEAQSS 239
S S + SS SRH SP + SR++ R + K D E++ S
Sbjct: 365 HSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGS 423
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.116 0.321
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,586,886
Number of Sequences: 37866
Number of extensions: 1489823
Number of successful extensions: 41517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 580
Number of HSP's successfully gapped in prelim test: 1211
Number of HSP's that attempted gapping in prelim test: 11498
Number of HSP's gapped (non-prelim): 11760
length of query: 611
length of database: 18,247,518
effective HSP length: 108
effective length of query: 503
effective length of database: 14,157,990
effective search space: 7121468970
effective search space used: 7121468970
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.