Guide to the Human Genome
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Search of human proteins with 50083277

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
         (1192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]           2392   0.0  
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s...  1731   0.0  
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]         1257   0.0  
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]         922   0.0  
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ...   843   0.0  
gi|157649069 ATPase, aminophospholipid transporter (APLT), class...   840   0.0  
gi|117168245 ATPase, aminophospholipid transporter-like, Class I...   831   0.0  
gi|62632750 ATPase, class VI, type 11B [Homo sapiens]                 660   0.0  
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]      638   0.0  
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]      635   0.0  
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]       633   0.0  
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]       632   0.0  
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s...   555   e-158
gi|41327760 ATPase, class II, type 9B [Homo sapiens]                  425   e-118
gi|14424433 ATPase, class V, type 10A [Homo sapiens]                  424   e-118
gi|149944474 ATPase, class V, type 10B [Homo sapiens]                 424   e-118
gi|222352161 ATPase, class V, type 10D [Homo sapiens]                 421   e-117
gi|65301139 ATPase, class II, type 9A [Homo sapiens]                  421   e-117
gi|66932949 ATPase type 13A4 [Homo sapiens]                            92   4e-18
gi|148839292 ATPase type 13A3 [Homo sapiens]                           81   7e-15
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...    76   2e-13
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...    76   2e-13
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...    72   2e-12
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...    72   2e-12
gi|66730421 ATPase type 13A5 [Homo sapiens]                            72   4e-12
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...    66   2e-10
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa...    66   2e-10
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...    65   5e-10
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap...    65   5e-10
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...    61   6e-09

>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
          Length = 1192

 Score = 2392 bits (6198), Expect = 0.0
 Identities = 1192/1192 (100%), Positives = 1192/1192 (100%)

Query: 1    MFCSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYF 60
            MFCSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYF
Sbjct: 1    MFCSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYF 60

Query: 61   LCLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINS 120
            LCLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINS
Sbjct: 61   LCLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINS 120

Query: 121  KLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALS 180
            KLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALS
Sbjct: 121  KLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALS 180

Query: 181  VTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTS 240
            VTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTS
Sbjct: 181  VTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTS 240

Query: 241  WCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWES 300
            WCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWES
Sbjct: 241  WCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWES 300

Query: 301  QTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWD 360
            QTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWD
Sbjct: 301  QTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWD 360

Query: 361  RKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDD 420
            RKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDD
Sbjct: 361  RKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDD 420

Query: 421  LDQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSE 480
            LDQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSE
Sbjct: 421  LDQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSE 480

Query: 481  ENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNT 540
            ENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNT
Sbjct: 481  ENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNT 540

Query: 541  RKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAY 600
            RKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAY
Sbjct: 541  RKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAY 600

Query: 601  RDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETV 660
            RDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETV
Sbjct: 601  RDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETV 660

Query: 661  TSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNL 720
            TSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNL
Sbjct: 661  TSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNL 720

Query: 721  FGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELAC 780
            FGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELAC
Sbjct: 721  FGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELAC 780

Query: 781  MCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQA 840
            MCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQA
Sbjct: 781  MCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQA 840

Query: 841  VLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQT 900
            VLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQT
Sbjct: 841  VLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQT 900

Query: 901  VYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVL 960
            VYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVL
Sbjct: 901  VYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVL 960

Query: 961  HGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFI 1020
            HGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFI
Sbjct: 961  HGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFI 1020

Query: 1021 NHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVM 1080
            NHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVM
Sbjct: 1021 NHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVM 1080

Query: 1081 PVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGE 1140
            PVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGE
Sbjct: 1081 PVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGE 1140

Query: 1141 LITSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL 1192
            LITSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL
Sbjct: 1141 LITSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL 1192


>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
            sapiens]
          Length = 1223

 Score = 1731 bits (4482), Expect = 0.0
 Identities = 841/1191 (70%), Positives = 1005/1191 (84%), Gaps = 7/1191 (0%)

Query: 3    CSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLC 62
            C++K+  E ER  +ANDREYNEKFQYA N I TSKYNILTFLP+NLFEQFQ VAN YFL 
Sbjct: 37   CAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 96

Query: 63   LLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKL 122
            LLILQLIP+ISSL+WFTTIVPLVLV+T+TAVKDATDDYFRHKSDNQVNNRQS+VLIN  L
Sbjct: 97   LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 156

Query: 123  QNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVT 182
            Q E+WMNV VGDIIKLENNQFVAADLLLLSSSEPHGLCY+ETAELDGETN+KVR A+ VT
Sbjct: 157  QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 216

Query: 183  SELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWC 242
            SELG DIS+LA FDG V+CE PNNKLDKF G L WK++K  L+N+ ++LRGC+LRNT WC
Sbjct: 217  SELG-DISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 275

Query: 243  FGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQT 302
            FG+VIFAGPDTKLMQNSG+TKFKRTSIDRLMNTLVLWIFGFL+C+G+ILAIGN+IWE + 
Sbjct: 276  FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 335

Query: 303  GDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRK 362
            G +F+ +L W+E   S+ FSGFL+FWSYIIILNTVVPISLYVSVEVIRLGHSYFINWD+K
Sbjct: 336  GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKK 395

Query: 363  MYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLD 422
            M+  +K  PA ARTTTLNEELGQ+EYIFSDKTGTLTQNIM F +CSING  YG+V D L 
Sbjct: 396  MFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLG 455

Query: 423  QKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEEN 482
             K E+ +  EPVDFS    AD++F F+D  L+E++K+GDP  HEF RLL+LCHTVMSEE 
Sbjct: 456  HKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEK 515

Query: 483  SAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRK 542
            + GEL Y+ QSPDEGALVTAARNFGF+F+SRTP+TIT+ E+GT +TYQLLA LDFNN RK
Sbjct: 516  NEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRK 575

Query: 543  RMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRD 602
            RMSVIVRNPEG+I+LY KGADTIL ++LH S + LL+ T DHL+E+AGEGLRTL +AY+D
Sbjct: 576  RMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKD 635

Query: 603  LDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTS 662
            LD++Y++EW +    A+ A + R++R+A +YEE+E ++MLLGATA+EDKLQ+GV ET+  
Sbjct: 636  LDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIAL 695

Query: 663  LSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFG 722
            L+LANIKIWVLTGDKQETA+NIGY+C MLTDDM +VF++ G+  +EVREELRKA++ +  
Sbjct: 696  LTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMD 755

Query: 723  QNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMC 782
             +R+  NG    +K    +L S++ E + G+YAL+INGHSLAHALE+D++ + LE AC C
Sbjct: 756  SSRSVGNGFTYQDKLSSSKLTSVL-EAVAGEYALVINGHSLAHALEADMELEFLETACAC 814

Query: 783  KTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVL 842
            K VICCRVTPLQKAQVVELVKKY+ AVTLAIGDGANDVSMIK+AHIGVGISGQEG+QAVL
Sbjct: 815  KAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVL 874

Query: 843  ASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVY 902
            ASDYSF+QF++LQRLLLVHGRWSY RMCKFLCYFFYKNFAFT+VHFWFGFFCGFSAQTVY
Sbjct: 875  ASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVY 934

Query: 903  DQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHG 962
            DQ+FITL+NIVYTSLPVLAMG+FDQDV +Q S++ P+LY+PGQLNLLFNKR+FFIC+  G
Sbjct: 935  DQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQG 994

Query: 963  IYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINH 1022
            IYTS+++FFIPYG F +   +DG  +ADYQSFAVT+ATSLVIVVSVQI LDT YWT INH
Sbjct: 995  IYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINH 1054

Query: 1023 VFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPV 1082
             FIWGS+A+YF+ILF MHSNG+F +FPNQF FVGNA+++L Q  +WL I+LTTV  +MPV
Sbjct: 1055 FFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPV 1114

Query: 1083 VAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYAFAHQEGYGELI 1142
            VAFRFL+++L P LSD +R  Q  +KK +       R  R+ SRRSGYAF+HQEG+GELI
Sbjct: 1115 VAFRFLRLNLKPDLSDTVRYTQLVRKKQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELI 1174

Query: 1143 TSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFS--QDKTVK 1191
             SGKNMR  +   +S    T  +S+SWIE+L +K +D+ SS S   DK +K
Sbjct: 1175 MSGKNMRLSSLALSS---FTTRSSSSWIESLRRKKSDSASSPSGGADKPLK 1222


>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
          Length = 1251

 Score = 1257 bits (3253), Expect = 0.0
 Identities = 647/1175 (55%), Positives = 844/1175 (71%), Gaps = 42/1175 (3%)

Query: 15   VKANDREYNE-------KF------QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFL 61
            VKANDR+Y+E       KF      +YA+N I T KYN  TF+P+NLFEQF+R AN YFL
Sbjct: 66   VKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFL 125

Query: 62   CLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSK 121
             LLILQ +P+IS+L W+TT+VPL++V+ +TA+KD  DD  RHK D ++NNR  EV+ + +
Sbjct: 126  ALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGR 185

Query: 122  LQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSV 181
             +  KW  ++VGD+I+L+ N FV AD+LLLSSSEP+ LCYVETAELDGETNLK + +L +
Sbjct: 186  FKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEI 245

Query: 182  TSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSW 241
            T +       LA FDG + CE PNN+LDKF G L W+++   L+ +KI+LRGC++RNT +
Sbjct: 246  TDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRNTDF 305

Query: 242  CFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQ 301
            C G+VIFAG DTK+M+NSGKT+FKRT ID LMN +V  IF  LI L   LAIG++ WE+Q
Sbjct: 306  CHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQ 365

Query: 302  TGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDR 361
             G+    +L+  E +  S + GFL FW YII+LNT+VPISLYVSVEVIRLG S+FINWD 
Sbjct: 366  VGNS-SWYLYDGEDDTPS-YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDL 423

Query: 362  KMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDL 421
            +MYY+ K  PA ARTTTLNE+LGQI YIFSDKTGTLTQNIMTFK+C ING+IYG+ H D 
Sbjct: 424  QMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGD-HRDA 482

Query: 422  DQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMG-DPKVHEFLRLLALCHTVMSE 480
             Q      + E VDFS  + AD +  F+DH+L+E I+ G +P+V +F  LLA+CHTVM +
Sbjct: 483  SQHNH--NKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVD 540

Query: 481  ENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNT 540
                G+L YQ  SPDEGALV AARNFGF F +RT  TITI ELGT  TY +LA LDFN+ 
Sbjct: 541  RTD-GQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSD 599

Query: 541  RKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAY 600
            RKRMS+IVR PEG IKLY KGADT+++E+LH  N      T D L  FA E LRTL + Y
Sbjct: 600  RKRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQE-TQDALDIFANETLRTLCLCY 658

Query: 601  RDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETV 660
            +++++K F EW+K    A+ A+  RDE +  +YEEIE+DL+LLGATA+EDKLQ+GV ET+
Sbjct: 659  KEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETI 718

Query: 661  TSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNL 720
            + L+ A+IKIWVLTGDK+ETA NIG+AC +LT+D    +    N+ +  R E ++ +  +
Sbjct: 719  SKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGV 778

Query: 721  F--------------GQNR------NFSNGHVVCEKKQQLELDSIVEETITGDYALIING 760
            +              G NR      ++ N  ++ +K ++ ++  +       +  +    
Sbjct: 779  YAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQS 838

Query: 761  HSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDV 820
                 A +   + + ++LAC C  VICCRVTP QKA VV+LVK+Y+ A+TLAIGDGANDV
Sbjct: 839  KRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDV 898

Query: 821  SMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKN 880
            +MIK+AHIGVGISGQEG+QAV++SDYSFAQFRYLQRLLLVHGRWSY RMCKFL YFFYKN
Sbjct: 899  NMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKN 958

Query: 881  FAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQL 940
            FAFTLVHFW+ FF G+SAQT Y+ WFITL+N++YTSLPVL MG+ DQDVSD+ S+  P L
Sbjct: 959  FAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGL 1018

Query: 941  YKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMAT 1000
            Y  GQ +LLFN ++FF+ +LHG+ TS++LFFIP GA+    G+DG+  +DYQSFAVT+A+
Sbjct: 1019 YIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIAS 1078

Query: 1001 SLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARH 1060
            +LVI V+ QI LDTSYWTF+N   I+GSIA+YF I+F  HS GI  +FP+ F F G A +
Sbjct: 1079 ALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASN 1138

Query: 1061 SLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRT 1120
            +L Q  IWL I+LT    ++PVVA RFL + ++P+ SD+I++ +K  K       R+   
Sbjct: 1139 ALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVF 1198

Query: 1121 RRS-SSRRSGYAFAHQEGYGELITSGKNMRAKNPP 1154
            RR  S+RRS YAF+HQ GY +LI+SG+++R K  P
Sbjct: 1199 RRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRSP 1233


>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
          Length = 1300

 Score =  922 bits (2382), Expect = 0.0
 Identities = 515/1194 (43%), Positives = 739/1194 (61%), Gaps = 90/1194 (7%)

Query: 15   VKANDREYNEKFQ-----------YADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCL 63
            V+AN+R YN +F+           Y  N I T+KYN  +FLP+NL+EQF RV+N +FL +
Sbjct: 109  VQANNRAYNGQFKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLII 168

Query: 64   LILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQ 123
            +ILQ IP+IS+L WF+   P+V ++ + A +D  DD  RHKSD  +NNR  ++L+    +
Sbjct: 169  IILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFK 228

Query: 124  NEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTS 183
             +KW ++ VGD++ L  +  V AD+LLL+S+EP  LCYVET ++DGETNLK R AL VT 
Sbjct: 229  QKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTH 288

Query: 184  ELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWCF 243
            +  A I ++A F G V CE PN+++  F+G L W D K+SL+   ++LRGC +RNT  C+
Sbjct: 289  KELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRNTDTCY 348

Query: 244  GMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIF--GFLICLGIILAIGNSIWESQ 301
            G+VI+AG DTK+M+N GK   KRT +D LMN LV+ IF    L+CL +    G S+ E  
Sbjct: 349  GLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKE-- 406

Query: 302  TGDQFRTFLFWNEGEKSS--VFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINW 359
                F+   ++  G   S      F  FWS++I+L+  +P+S+++  E I LG+S FI+W
Sbjct: 407  ----FKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDW 462

Query: 360  DRKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHD 419
            D +MYY  + +PA AR+T+LN+ LGQ+EYIFSDKTGTLTQNI+TF +C I+GR+YG    
Sbjct: 463  DVQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYG---- 518

Query: 420  DLDQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKM-GDPKVHEFLRLLALCHTVM 478
                 +E T   +   +     AD +  F +  L+  ++  GD  V EF RLLA+CHTVM
Sbjct: 519  ---PDSEATTRPKENPYLWNKFADGKLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVM 575

Query: 479  SEEN---SAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFL 535
              E+      +L+YQ  SPDEGALVTAARNFG++F SRT +T+TI ELG    YQ+LA +
Sbjct: 576  VRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIM 635

Query: 536  DFNNTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRT 595
            DFN+TRKRMSV+VR PEG I LY+KGADT++FE+LH    +  + T + L+ FA E LRT
Sbjct: 636  DFNSTRKRMSVLVRKPEGAICLYTKGADTVIFERLHRRGAMEFA-TEEALAAFAQETLRT 694

Query: 596  LAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEG 655
            L +AYR++ +  +++W +  ++A+   + R + +            LLGATA+ED+LQ+G
Sbjct: 695  LCLAYREVAEDIYEDWQQRHQEASLLLQNRAQALQ----------QLLGATAIEDRLQDG 744

Query: 656  VIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDM-----NDVFVI-----AGNN 705
            V ET+  L  +NIKIWVLTGDKQETA+NIG+AC +L+++M      ++  I       +N
Sbjct: 745  VPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSN 804

Query: 706  AVEVREELRKAKQNLFGQNRNFSNGHVVCEKK------QQLELDSIVEE--------TIT 751
             +  RE L + K  L   N +F +  +V  +K      Q + +D   +E           
Sbjct: 805  NLLTRESLSQVKLALV-INGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA 863

Query: 752  GDYALIINGHSLAHAL----------ESDVKND--LLELACMCKTVICCRVTPLQKAQVV 799
               +L+     L  A            S+V  +   ++LA  C+ VICCRVTP QKA +V
Sbjct: 864  RRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIV 923

Query: 800  ELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLL 859
             LVKKY   VTLAIGDGAND++MIK+A +GVG++GQEG+QAV  SD+   QF +LQRLLL
Sbjct: 924  ALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLL 983

Query: 860  VHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPV 919
            VHGRWSY R+CKFL YFFYK+ A  +V  WF  + GF+ Q +Y+ WF+ LFN++Y++LPV
Sbjct: 984  VHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPV 1043

Query: 920  LAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYN 979
            L +G+F+QDVS + S++ P+LY  GQ + LFN   F   + HG+ TSLV FF+      +
Sbjct: 1044 LYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRD 1103

Query: 980  VAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTM 1039
             AG      +D+QSFAV +A S ++ +++++ L   YWT +    I  S+  Y  +  T 
Sbjct: 1104 TAGP--ASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTT 1161

Query: 1040 HSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQ 1099
             S  +F + P  FPF+      ++   I LV+LL+   +  PV+A R     ++P L + 
Sbjct: 1162 QSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALRV----IFPALKEL 1217

Query: 1100 IRRWQKAQK-KARPPSSRRPRT---RRSSSRRSGYAFAHQEGYGELITSGKNMR 1149
              + +K ++  +    +  P     R S +RRS YAF+H+EGY  LIT G  +R
Sbjct: 1218 RAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGYANLITQGTILR 1271


>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
            type 8A, member 1 isoform a [Homo sapiens]
          Length = 1164

 Score =  843 bits (2179), Expect = 0.0
 Identities = 456/1094 (41%), Positives = 688/1094 (62%), Gaps = 50/1094 (4%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            ++ +N + T+KYNI+TFLP  L+ QF+R AN++FL + +LQ IP++S    +TT+VPL+ 
Sbjct: 48   KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            ++ + A+K+  +D  RHK+DN VN +Q++VL N   +   W  V VG+I+K+ N + + A
Sbjct: 108  ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            DL+ LSSSEP  +CY+ET+ LDGETNLK+R  L  TS++  D+  L    G + CE PN 
Sbjct: 168  DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDI-KDVDSLMRISGRIECESPNR 226

Query: 207  KLDKFMGILSWKD-SKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
             L  F+G +         L  ++I+LRG  LRNT W  G+V++ G DTKLMQNS     K
Sbjct: 227  HLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLK 286

Query: 266  RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGFL 325
             ++++R+ N  +L +F  LI + ++ ++G++IW  +   +   +L  N G  S+    FL
Sbjct: 287  LSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-DWYLNLNYGGASNFGLNFL 345

Query: 326  TFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQ 385
            TF   II+ N ++PISL V++EV++   +YFINWD  M+Y      A+ART+ LNEELGQ
Sbjct: 346  TF---IILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402

Query: 386  IEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKSQADRE 445
            ++YIFSDKTGTLT N+M FK+C+I G  YG V +  D      + +        SQ   E
Sbjct: 403  VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQN-------SQFGDE 455

Query: 446  FQFFDHHLMESIKMGDPK---VHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALVTA 502
              F D  L+E+++   P    + EFL ++A+CHT + E     ++IYQ  SPDEGALV A
Sbjct: 456  KTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREG-DKIIYQAASPDEGALVRA 514

Query: 503  ARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGA 562
            A+   F+F  RTP+++ I+ LG    Y+LL  L+F + RKRMSVIVR P G+++LY KGA
Sbjct: 515  AKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 574

Query: 563  DTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAAT 622
            DT+++++L  +++    +T  HL +FA EGLRTL  A  ++ +  F+EW  + + A+ + 
Sbjct: 575  DTVIYDRLAETSKYK-EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSV 633

Query: 623  EERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAI 682
            + R  ++   YE IE++L LLGATA+EDKLQ+ V ET+ +L  A+IKIW+LTGDKQETAI
Sbjct: 634  QNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAI 693

Query: 683  NIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLEL 742
            NIG++C +L  +M  + VI   +    RE L +    L                      
Sbjct: 694  NIGHSCKLLKKNMG-MIVINEGSLDGTRETLSRHCTTLG--------------------- 731

Query: 743  DSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELV 802
            D++ +E    D+ALII+G +L +AL   V+   L+LA  CK VICCRV+PLQK++VVE+V
Sbjct: 732  DALRKEN---DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV 788

Query: 803  KKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHG 862
            KK    VTLAIGDGANDVSMI++AH+GVGISG EGLQA  +SDYS AQF+YL+ LL++HG
Sbjct: 789  KKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHG 848

Query: 863  RWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAM 922
             W+Y R+ K + Y FYKN    ++  WF F  GFS Q ++++W I L+N+++T++P L +
Sbjct: 849  AWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTL 908

Query: 923  GIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAF-YNVA 981
            GIF++    +N +  P+LYK  Q  L FN + F++  L+G++ S++LF+ P  A  Y  A
Sbjct: 909  GIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTA 968

Query: 982  GEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHS 1041
              +G+  +DY      + T +VI V ++  L+TSYWT+ +H+ IWGSIA++  + F ++S
Sbjct: 969  FGNGK-TSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV-VFFGIYS 1026

Query: 1042 NGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIR 1101
            + ++   P      G A    +    W+ +L   VAS++  V ++ +K   + TL D++ 
Sbjct: 1027 S-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEV- 1084

Query: 1102 RWQKAQKKARPPSS 1115
              Q+ + K++ P +
Sbjct: 1085 --QELEAKSQDPGA 1096


>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
            type 8A, member 1 isoform b [Homo sapiens]
          Length = 1149

 Score =  840 bits (2170), Expect = 0.0
 Identities = 453/1094 (41%), Positives = 685/1094 (62%), Gaps = 65/1094 (5%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            ++ +N + T+KYNI+TFLP  L+ QF+R AN++FL + +LQ IP++S    +TT+VPL+ 
Sbjct: 48   KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            ++ + A+K+  +D  RHK+DN VN +Q++VL N   +   W  V VGDI+ ++  +++ A
Sbjct: 108  ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            D +LLSSSEP  +CY+ET+ LDGETNLK+R  L  TS++  D+  L    G + CE PN 
Sbjct: 168  DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDI-KDVDSLMRISGRIECESPNR 226

Query: 207  KLDKFMGILSWKD-SKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
             L  F+G +         L  ++I+LRG  LRNT W  G+V++ G DTKLMQNS     K
Sbjct: 227  HLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLK 286

Query: 266  RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGFL 325
             ++++R+ N  +L +F  LI + ++ ++G++IW  +   +   +L  N G  S+    FL
Sbjct: 287  LSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-DWYLNLNYGGASNFGLNFL 345

Query: 326  TFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQ 385
            TF   II+ N ++PISL V++EV++   +YFINWD  M+Y      A+ART+ LNEELGQ
Sbjct: 346  TF---IILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402

Query: 386  IEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKSQADRE 445
            ++YIFSDKTGTLT N+M FK+C+I G  YG+     D+KT                    
Sbjct: 403  VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKT-------------------- 442

Query: 446  FQFFDHHLMESIKMGDPK---VHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALVTA 502
              F D  L+E+++   P    + EFL ++A+CHT + E     ++IYQ  SPDEGALV A
Sbjct: 443  --FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREG-DKIIYQAASPDEGALVRA 499

Query: 503  ARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGA 562
            A+   F+F  RTP+++ I+ LG    Y+LL  L+F + RKRMSVIVR P G+++LY KGA
Sbjct: 500  AKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 559

Query: 563  DTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAAT 622
            DT+++++L  +++    +T  HL +FA EGLRTL  A  ++ +  F+EW  + + A+ + 
Sbjct: 560  DTVIYDRLAETSKYK-EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSV 618

Query: 623  EERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAI 682
            + R  ++   YE IE++L LLGATA+EDKLQ+ V ET+ +L  A+IKIW+LTGDKQETAI
Sbjct: 619  QNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAI 678

Query: 683  NIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLEL 742
            NIG++C +L  +M  + VI   +    RE L +    L                      
Sbjct: 679  NIGHSCKLLKKNMG-MIVINEGSLDGTRETLSRHCTTLG--------------------- 716

Query: 743  DSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELV 802
            D++ +E    D+ALII+G +L +AL   V+   L+LA  CK VICCRV+PLQK++VVE+V
Sbjct: 717  DALRKEN---DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV 773

Query: 803  KKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHG 862
            KK    VTLAIGDGANDVSMI++AH+GVGISG EGLQA  +SDYS AQF+YL+ LL++HG
Sbjct: 774  KKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHG 833

Query: 863  RWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAM 922
             W+Y R+ K + Y FYKN    ++  WF F  GFS Q ++++W I L+N+++T++P L +
Sbjct: 834  AWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTL 893

Query: 923  GIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAF-YNVA 981
            GIF++    +N +  P+LYK  Q  L FN + F++  L+G++ S++LF+ P  A  Y  A
Sbjct: 894  GIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTA 953

Query: 982  GEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHS 1041
              +G+  +DY      + T +VI V ++  L+TSYWT+ +H+ IWGSIA++  + F ++S
Sbjct: 954  FGNGK-TSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV-VFFGIYS 1011

Query: 1042 NGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIR 1101
            + ++   P      G A    +    W+ +L   VAS++  V ++ +K   + TL D++ 
Sbjct: 1012 S-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEV- 1069

Query: 1102 RWQKAQKKARPPSS 1115
              Q+ + K++ P +
Sbjct: 1070 --QELEAKSQDPGA 1081


>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
            type 8A, member 2 [Homo sapiens]
          Length = 1188

 Score =  831 bits (2147), Expect = 0.0
 Identities = 453/1091 (41%), Positives = 675/1091 (61%), Gaps = 51/1091 (4%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            ++ DN+I T+KY++LTFLP  L+EQ +R ANA+FL + +LQ IP++S    +TT+VPL++
Sbjct: 67   KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            ++T+  +K+  +D+ RHK+DN VN +++ VL N       W  V VGDI+K+ N Q++ A
Sbjct: 127  ILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPA 186

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            D++LLSSSEP  +CYVETA LDGETNLK+R  LS T+++      L    G + CE PN 
Sbjct: 187  DVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTR-EVLMKLSGTIECEGPNR 245

Query: 207  KLDKFMGILSWK-DSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
             L  F G L+    S  +L  ++I+LRG  LRNT W FG+V++ G DTKLMQNS K   K
Sbjct: 246  HLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLK 305

Query: 266  RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGF- 324
            R++++++ N  +L +FG L+ + ++ + G   W    G++      W   +  +    F 
Sbjct: 306  RSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEK-----NWYIKKMDTTSDNFG 360

Query: 325  LTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELG 384
                ++II+ N ++PISL V++EV++   + FINWD  MYY     PA+ART+ LNEELG
Sbjct: 361  YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELG 420

Query: 385  QIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDF-SVKSQAD 443
            Q++Y+FSDKTGTLT NIM FK+CSI G  YG          E+ +E    DF  +     
Sbjct: 421  QVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHF-------PELAREPSSDDFCRMPPPCS 473

Query: 444  REFQFFDHHLMESIKMGDPK---VHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
                F D  L+++I+   P    + EFL LLA+CHTV+ E++    +IYQ  SPDE ALV
Sbjct: 474  DSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKD-GDNIIYQASSPDEAALV 532

Query: 501  TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
              A+  GF+F +RTP ++ IE +G   T+ +L  L+F++ RKRMSVIVR P G+++LY K
Sbjct: 533  KGAKKLGFVFTARTPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCK 592

Query: 561  GADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANA 620
            GAD ++FE+L   ++  +  T  HL  FA EGLRTL +AY DL +  ++EW K+ ++A+ 
Sbjct: 593  GADNVIFERLSKDSK-YMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEAST 651

Query: 621  ATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQET 680
              ++R +R+   YE IE++L+LLGATA+ED+LQ GV ET+ +L  A IKIWVLTGDKQET
Sbjct: 652  ILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQET 711

Query: 681  AINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQL 740
            AINIGY+C +++ +M  + +                K++     R     H         
Sbjct: 712  AINIGYSCRLVSQNMALILL----------------KEDSLDATRAAITQHCT------- 748

Query: 741  ELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVE 800
            +L +++ +    D ALII+GH+L +AL  +V+   L+LA  CK VICCRV+PLQK+++V+
Sbjct: 749  DLGNLLGK--ENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVD 806

Query: 801  LVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLV 860
            +VKK   A+TLAIGDGANDV MI++AH+GVGISG EG+QA   SDY+ AQF YL++LLLV
Sbjct: 807  VVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLV 866

Query: 861  HGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVL 920
            HG WSY R+ K + Y FYKN    ++  WF F  GFS Q ++++W I L+N+++T+LP  
Sbjct: 867  HGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPF 926

Query: 921  AMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNV 980
             +GIF++  + ++ +  PQLYK  Q    FN + F+   ++ +  SL+LF+ P  A  + 
Sbjct: 927  TLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFPMKALEHD 986

Query: 981  AGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMH 1040
                  H  DY      + T +V+ V ++  L+T+ WT  +H+ +WGS+  +  + F ++
Sbjct: 987  TVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL-VFFGIY 1045

Query: 1041 SNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQI 1100
            S  I+   P      G A   L+    WL + L   A ++  VA+R  K     TL +++
Sbjct: 1046 ST-IWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKTLLEEV 1104

Query: 1101 RRWQKAQKKAR 1111
               Q+ + K+R
Sbjct: 1105 ---QELETKSR 1112


>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
          Length = 1177

 Score =  660 bits (1702), Expect = 0.0
 Identities = 399/1111 (35%), Positives = 619/1111 (55%), Gaps = 82/1111 (7%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            ++ DNRI +SKY +  F+P NLFEQF+RVAN YFL + ++QL+ +  +    T+ +PL  
Sbjct: 38   KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSP-VTSGLPLFF 96

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            VIT+TA+K   +D+ RH SDN+VN     V+ +  L   +  N++VGDI+++  ++   A
Sbjct: 97   VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            DL+LLSS    G C+V TA LDGETNLK   A+  T+ L   ++ L     ++ C+ P  
Sbjct: 157  DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQT-VANLDTLVAVIECQQPEA 215

Query: 207  KLDKFMGIL----SWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKT 262
             L +FMG +      ++    L  E ++LRG  L+NT   FG+ ++ G +TK+  N    
Sbjct: 216  DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275

Query: 263  KFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQT--GDQFRTFLFWNEGEKSSV 320
              KR+++++ MNT ++     LI   +I  I    W+++    + +      ++   S +
Sbjct: 276  SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335

Query: 321  FSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLN 380
                  F +++++ N ++PISLYV+VE+ +   S+FI WD  +Y+      A   T+ LN
Sbjct: 336  LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395

Query: 381  EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
            EELGQ+EY+F+DKTGTLT+N M F+ CSING  Y E++  L  +   T +    + S  S
Sbjct: 396  EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGP-TPDSSEGNLSYLS 454

Query: 441  QADREFQFFDHHLMESIKMGDP-------KVHE-FLRLLALCHTVMS------------- 479
                      H    S     P       K H+ F + ++LCHTV               
Sbjct: 455  SLSH-LNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPW 513

Query: 480  EENSA-GELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFN 538
            + N A  +L Y   SPDE ALV AA   G +F   + ET+ ++ LG L  Y+LL  L+F+
Sbjct: 514  QSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFD 573

Query: 539  NTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAI 598
            + R+RMSVIV+ P G+  L++KGA++ +  K        +  T  H+ EFA +GLRTL I
Sbjct: 574  SDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGE---IEKTRIHVDEFALKGLRTLCI 630

Query: 599  AYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIE 658
            AYR    K ++E  K + +A  A ++R+E++A +++ IE+DL+LLGATAVED+LQ+ V E
Sbjct: 631  AYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRE 690

Query: 659  TVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQ 718
            T+ +L +A IK+WVLTGDK ETA+++  +C      MN + +I   +  E  E+LR+   
Sbjct: 691  TIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLA- 749

Query: 719  NLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLEL 778
                  R  +  HV+                    + L+++G SL+ AL    K   +E+
Sbjct: 750  ------RRITEDHVI-------------------QHGLVVDGTSLSLALREHEKL-FMEV 783

Query: 779  ACMCKTVICCRVTPLQKAQVVELVK-KYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEG 837
               C  V+CCR+ PLQKA+V+ L+K      +TLA+GDGANDVSMI+ AH+G+GI G+EG
Sbjct: 784  CRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEG 843

Query: 838  LQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFS 897
             QA   SDY+ A+F++L +LL VHG + Y R+   + YFFYKN  F    F + F+C FS
Sbjct: 844  RQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFS 903

Query: 898  AQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFI 957
             QT+YD  ++TL+NI +TSLP+L   + +Q V      + P LY+    N L + + F  
Sbjct: 904  QQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLY 963

Query: 958  CVLHGIYTSLVLFFIPY---GAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDT 1014
              + G   + + FF  Y   G   ++ G +GQ   ++ +F   + T +VI V+V++AL+T
Sbjct: 964  WTILGFSHAFIFFFGSYLLIGKDTSLLG-NGQMFGNW-TFGTLVFTVMVITVTVKMALET 1021

Query: 1015 SYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNAR------HSLTQKCIW 1068
             +WT+INH+  WGSI  YF  +F++   GI       +PF+G+          L+    W
Sbjct: 1022 HFWTWINHLVTWGSIIFYF--VFSLFYGGIL------WPFLGSQNMYFVFIQLLSSGSAW 1073

Query: 1069 LVILLTTVASVMPVVAFRFLKVDLYPTLSDQ 1099
              I+L  V  +   +  +     L+PT +++
Sbjct: 1074 FAIILMVVTCLFLDIIKKVFDRHLHPTSTEK 1104


>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
          Length = 1191

 Score =  638 bits (1646), Expect = 0.0
 Identities = 399/1189 (33%), Positives = 633/1189 (53%), Gaps = 85/1189 (7%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            +Y DNRI +SKY    F+P NLFEQF+RVAN YFL + ++QLI +  +    T+ +PL  
Sbjct: 44   RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSP-VTSGLPLFF 102

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            VIT+TA+K   +D+ RHK+DN +N      + + KL  ++   ++VGDI+ ++ ++    
Sbjct: 103  VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            DL+ LSS+   G C+V TA LDGE++ K  +A+  T     +   + G    + CE P  
Sbjct: 163  DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTE-EDIGGLHATIECEQPQP 221

Query: 207  KLDKFMGILSWKDSKHS-----LNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGK 261
             L KF+G ++     +      L +E ++LRG  L+NT   FG+ I+ G +TK+  N   
Sbjct: 222  DLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQS 281

Query: 262  TKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWN-----EGE 316
               KR+++++ MN  ++     LI   +I  +   +W+S+    FR   ++N     E +
Sbjct: 282  KSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEP---FRDEPWYNQKTESERQ 338

Query: 317  KSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVART 376
            ++     F  F +++++ N ++P+S+YV+VE+ +   SYFI WD  M+        +  T
Sbjct: 339  RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398

Query: 377  TTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDF 436
            + LNEELGQ+EYIF+DKTGTLT+N M FK C I G +Y      +    ++  E   +D 
Sbjct: 399  SDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVP---HVICNGQVLPESSGIDM 455

Query: 437  SVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGE---------- 486
               S +                 G  +   F R L LCHTV  +++ + +          
Sbjct: 456  IDSSPSVN---------------GREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGK 500

Query: 487  -LIYQVQSPDEGALVTAARNFGFIF---KSRTPETITIEELGTLVTYQLLAFLDFNNTRK 542
              +Y   SPDE ALV   +  GF +   K    E +  E    +  ++LL  L F++ R+
Sbjct: 501  SCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNREN--HIERFELLEILSFDSVRR 558

Query: 543  RMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRD 602
            RMSVIV++  G+I L+ KGAD+ +F ++    E  +      +   A EGLRTL +AY+ 
Sbjct: 559  RMSVIVKSATGEIYLFCKGADSSIFPRVI---EGKVDQIRARVERNAVEGLRTLCVAYKR 615

Query: 603  LDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTS 662
            L  + ++   K+L+ A  A ++R++++A  YE+IE+DL LLGATAVED+LQE   +T+ +
Sbjct: 616  LIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEA 675

Query: 663  LSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFG 722
            L  A IK+WVLTGDK ETA    YAC +   +   +           R E +     LF 
Sbjct: 676  LQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLL------ELTTKRIEEQSLHDVLFE 729

Query: 723  QNRNF--SNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALE-------SDVKN 773
             ++     +G +  +    L  D         DY LII+G +L+  ++        + + 
Sbjct: 730  LSKTVLRHSGSLTRDNLSGLSAD-------MQDYGLIIDGAALSLIMKPREDGSSGNYRE 782

Query: 774  DLLELACMCKTVICCRVTPLQKAQVVELVK-KYRNAVTLAIGDGANDVSMIKSAHIGVGI 832
              LE+   C  V+CCR+ PLQKAQ+V+L+K    + +TLAIGDGANDVSMI  AH+G+G+
Sbjct: 783  LFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGV 842

Query: 833  SGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGF 892
             G+EG QA   SDY+  +F++L+++LLVHG + Y R+ + + YFFYKN  F    F + F
Sbjct: 843  IGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQF 902

Query: 893  FCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNK 952
            FCGFS QT+YD  ++TL+NI +TSLP+L   + +Q V        P LY+    N L   
Sbjct: 903  FCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRW 962

Query: 953  RKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIAL 1012
            R F    L G++ +LV FF  Y  F N        I    +F   + T +V  V++++AL
Sbjct: 963  RVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLAL 1022

Query: 1013 DTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVIL 1072
            DT YWT+INH  IWGS+  Y  ++F++   G+   F N           L+    WL I+
Sbjct: 1023 DTHYWTWINHFVIWGSLLFY--VVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIV 1080

Query: 1073 LTTVASVMPVVAFRFLKVDLYPTLSDQIRRW----QKAQKKARPPSSRRPRTRRSSSRRS 1128
            L    S++P V  + L   L+PT +++++      +    +  P +S +    +S+   +
Sbjct: 1081 LLVTISLLPDVLKKVLCRQLWPTATERVQNGCAQPRDRDSEFTPLASLQSPGYQSTCPSA 1140

Query: 1129 GYAFAHQEGYGELITSGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKT 1177
             +  +H +     + + K   +  PPP  G   +H++ +S   + C ++
Sbjct: 1141 AWYSSHSQQV--TLAAWKEKVSTEPPPILG--GSHHHCSSIPSHSCPRS 1185


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score =  635 bits (1639), Expect = 0.0
 Identities = 387/1109 (34%), Positives = 601/1109 (54%), Gaps = 77/1109 (6%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            +Y DNRI +SKY    F+P NLFEQF+RVAN YFL + ++QLI +  +    T+ +PL  
Sbjct: 44   RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSP-VTSGLPLFF 102

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            VIT+TA+K   +D+ RHK+DN +N      + + KL  ++   ++VGDI+ ++ ++    
Sbjct: 103  VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            DL+ LSS+   G C+V TA LDGE++ K  +A+  T     +   + G    + CE P  
Sbjct: 163  DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTE-EDIGGLHATIECEQPQP 221

Query: 207  KLDKFMGILSWKDSKHS-----LNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGK 261
             L KF+G ++     +      L +E ++LRG  L+NT   FG+ I+ G +TK+  N   
Sbjct: 222  DLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQS 281

Query: 262  TKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWN-----EGE 316
               KR+++++ MN  ++     LI   +I  +   +W+S+    FR   ++N     E +
Sbjct: 282  KSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEP---FRDEPWYNQKTESERQ 338

Query: 317  KSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVART 376
            ++     F  F +++++ N ++P+S+YV+VE+ +   SYFI WD  M+        +  T
Sbjct: 339  RNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNT 398

Query: 377  TTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDF 436
            + LNEELGQ+EYIF+DKTGTLT+N M FK C I G +Y      +    ++  E   +D 
Sbjct: 399  SDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVP---HVICNGQVLPESSGIDM 455

Query: 437  SVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGE---------- 486
               S +                 G  +   F R L LCHTV  +++ + +          
Sbjct: 456  IDSSPSVN---------------GREREELFFRALCLCHTVQVKDDDSVDGPRKSPDGGK 500

Query: 487  -LIYQVQSPDEGALVTAARNFGFIF---KSRTPETITIEELGTLVTYQLLAFLDFNNTRK 542
              +Y   SPDE ALV   +  GF +   K    E +  E    +  ++LL  L F++ R+
Sbjct: 501  SCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNREN--HIERFELLEILSFDSVRR 558

Query: 543  RMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRD 602
            RMSVIV++  G+I L+ KGAD+ +F ++    E  +      +   A EGLRTL +AY+ 
Sbjct: 559  RMSVIVKSATGEIYLFCKGADSSIFPRVI---EGKVDQIRARVERNAVEGLRTLCVAYKR 615

Query: 603  LDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTS 662
            L  + ++   K+L+ A  A ++R++++A  YE+IE+DL LLGATAVED+LQE   +T+ +
Sbjct: 616  LIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEA 675

Query: 663  LSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFG 722
            L  A IK+WVLTGDK ETA    YAC +   +   +           R E +     LF 
Sbjct: 676  LQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLL------ELTTKRIEEQSLHDVLFE 729

Query: 723  QNRNF--SNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALE-------SDVKN 773
             ++     +G +  +    L  D         DY LII+G +L+  ++        + + 
Sbjct: 730  LSKTVLRHSGSLTRDNLSGLSAD-------MQDYGLIIDGAALSLIMKPREDGSSGNYRE 782

Query: 774  DLLELACMCKTVICCRVTPLQKAQVVELVK-KYRNAVTLAIGDGANDVSMIKSAHIGVGI 832
              LE+   C  V+CCR+ PLQKAQ+V+L+K    + +TLAIGDGANDVSMI  AH+G+G+
Sbjct: 783  LFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGV 842

Query: 833  SGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGF 892
             G+EG QA   SDY+  +F++L+++LLVHG + Y R+ + + YFFYKN  F    F + F
Sbjct: 843  IGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQF 902

Query: 893  FCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNK 952
            FCGFS QT+YD  ++TL+NI +TSLP+L   + +Q V        P LY+    N L   
Sbjct: 903  FCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRW 962

Query: 953  RKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIAL 1012
            R F    L G++ +LV FF  Y  F N        I    +F   + T +V  V++++AL
Sbjct: 963  RVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLAL 1022

Query: 1013 DTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVIL 1072
            DT YWT+INH  IWGS+  Y  ++F++   G+   F N           L+    WL I+
Sbjct: 1023 DTHYWTWINHFVIWGSLLFY--VVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIV 1080

Query: 1073 LTTVASVMPVVAFRFLKVDLYPTLSDQIR 1101
            L    S++P V  + L   L+PT +++++
Sbjct: 1081 LLVTISLLPDVLKKVLCRQLWPTATERVQ 1109


>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
          Length = 1119

 Score =  633 bits (1633), Expect = 0.0
 Identities = 387/1133 (34%), Positives = 597/1133 (52%), Gaps = 83/1133 (7%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            ++ DNRI +SKY +  FLP NLFEQF+R+AN YFL + ++Q+  +  +    T+ +PL  
Sbjct: 42   RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            VIT+TA+K   +D+ RH++DN+VN     ++ N+K   ++   +KVGD+++++ ++    
Sbjct: 101  VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            DL+LLSS    G CYV TA LDGE+N K  +A+  T  L      +      + CE P  
Sbjct: 161  DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIAL-CTAESIDTLRAAIECEQPQP 219

Query: 207  KLDKFMGIL-----SWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGK 261
             L KF+G +     S +    SL  E ++L+G  L+NT   +G+ ++ G +TK+  N   
Sbjct: 220  DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279

Query: 262  TKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQ--TGDQFRTFLFWNEGEKSS 319
               KR+++++ +N  ++     L+    +      +W+S     + +       E E   
Sbjct: 280  KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339

Query: 320  VFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTL 379
            V   F  F S++++ N ++P+S+YV+VE+ +   S+FI+WD+  Y       A+  T+ L
Sbjct: 340  VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399

Query: 380  NEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVK 439
            NEELGQ++Y+F+DKTGTLT+N M F  C I+G  Y  V  ++D                 
Sbjct: 400  NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDG---------------L 444

Query: 440  SQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSA-------GELIYQVQ 492
            SQ D    +FD       K+   +   FLR L LCHTV  + N A        EL Y   
Sbjct: 445  SQTDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISS 497

Query: 493  SPDEGALVTAARNFGFIFKSRTPETITIE-ELGTLVTYQLLAFLDFNNTRKRMSVIVRNP 551
            SPDE ALV  A+ +GF F       + +E +   +  Y+LL  L+F+  R+RMSVIV+  
Sbjct: 498  SPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQ 557

Query: 552  EGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEW 611
            EG I L+ KGAD+ +F ++       + LT  H+   A +G RTL +A++++    ++  
Sbjct: 558  EGDILLFCKGADSAVFPRVQNHE---IELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614

Query: 612  HKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIW 671
            ++ L +A  A ++R+E++  ++++IE ++ L+GATAVEDKLQ+   ET+ +L  A +K+W
Sbjct: 615  NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674

Query: 672  VLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGH 731
            VLTGDK ETA +  YAC +     N   +      +E  E        L  + R      
Sbjct: 675  VLTGDKMETAKSTCYACRLF--QTNTELLELTTKTIEESERKEDRLHELLIEYR------ 726

Query: 732  VVCEKKQQLELDSIVEE-----TITGDYALIINGHSLAHALES-------DVKNDLLELA 779
                KK   E            T   +Y LII+G +L+  L S       + K+  L++ 
Sbjct: 727  ----KKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQIC 782

Query: 780  CMCKTVICCRVTPLQKAQVVELVKKYRNA-VTLAIGDGANDVSMIKSAHIGVGISGQEGL 838
              C  V+CCR+ PLQKAQ+V +VK  + + +TL+IGDGANDVSMI  +H+G+GI G+EG 
Sbjct: 783  MKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGR 842

Query: 839  QAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSA 898
            QA   SDYS  +F++L++LLL HG   Y R+   + YFFYKN  F L  F + FFCGFS 
Sbjct: 843  QAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQ 902

Query: 899  QTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFIC 958
            Q +YD  ++T++NI +TSLP+LA  + +Q ++       P+LY     N +     F   
Sbjct: 903  QPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYW 962

Query: 959  VLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWT 1018
                 +   V FF  Y  F   + E+   +    +F   + T LV  V++++ALDT +WT
Sbjct: 963  TFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWT 1022

Query: 1019 FINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVAS 1078
            +INH  IWGS+A Y  + F+    GI   F  Q          L+    WL I+L    S
Sbjct: 1023 WINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080

Query: 1079 VMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRTRRSSSRRSGYA 1131
            + P +    LK          +RR     + AR P+   P         SGY+
Sbjct: 1081 LFPEILLIVLK---------NVRR-----RSARNPNLELPMLLSYKHTDSGYS 1119


>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
          Length = 1132

 Score =  632 bits (1629), Expect = 0.0
 Identities = 378/1091 (34%), Positives = 584/1091 (53%), Gaps = 69/1091 (6%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            ++ DNRI +SKY +  FLP NLFEQF+R+AN YFL + ++Q+  +  +    T+ +PL  
Sbjct: 42   RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            VIT+TA+K   +D+ RH++DN+VN     ++ N+K   ++   +KVGD+++++ ++    
Sbjct: 101  VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
            DL+LLSS    G CYV TA LDGE+N K  +A+  T  L      +      + CE P  
Sbjct: 161  DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIAL-CTAESIDTLRAAIECEQPQP 219

Query: 207  KLDKFMGIL-----SWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGK 261
             L KF+G +     S +    SL  E ++L+G  L+NT   +G+ ++ G +TK+  N   
Sbjct: 220  DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279

Query: 262  TKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQ--TGDQFRTFLFWNEGEKSS 319
               KR+++++ +N  ++     L+    +      +W+S     + +       E E   
Sbjct: 280  KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339

Query: 320  VFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTL 379
            V   F  F S++++ N ++P+S+YV+VE+ +   S+FI+WD+  Y       A+  T+ L
Sbjct: 340  VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399

Query: 380  NEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVK 439
            NEELGQ++Y+F+DKTGTLT+N M F  C I+G  Y  V  ++D                 
Sbjct: 400  NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDG---------------L 444

Query: 440  SQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSA-------GELIYQVQ 492
            SQ D    +FD       K+   +   FLR L LCHTV  + N A        EL Y   
Sbjct: 445  SQTDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISS 497

Query: 493  SPDEGALVTAARNFGFIFKSRTPETITIE-ELGTLVTYQLLAFLDFNNTRKRMSVIVRNP 551
            SPDE ALV  A+ +GF F       + +E +   +  Y+LL  L+F+  R+RMSVIV+  
Sbjct: 498  SPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQ 557

Query: 552  EGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEW 611
            EG I L+ KGAD+ +F ++       + LT  H+   A +G RTL +A++++    ++  
Sbjct: 558  EGDILLFCKGADSAVFPRVQNHE---IELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614

Query: 612  HKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIW 671
            ++ L +A  A ++R+E++  ++++IE ++ L+GATAVEDKLQ+   ET+ +L  A +K+W
Sbjct: 615  NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674

Query: 672  VLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGH 731
            VLTGDK ETA +  YAC +     N   +      +E  E        L  + R      
Sbjct: 675  VLTGDKMETAKSTCYACRLF--QTNTELLELTTKTIEESERKEDRLHELLIEYR------ 726

Query: 732  VVCEKKQQLELDSIVEE-----TITGDYALIINGHSLAHALES-------DVKNDLLELA 779
                KK   E            T   +Y LII+G +L+  L S       + K+  L++ 
Sbjct: 727  ----KKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQIC 782

Query: 780  CMCKTVICCRVTPLQKAQVVELVKKYRNA-VTLAIGDGANDVSMIKSAHIGVGISGQEGL 838
              C  V+CCR+ PLQKAQ+V +VK  + + +TL+IGDGANDVSMI  +H+G+GI G+EG 
Sbjct: 783  MKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGR 842

Query: 839  QAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSA 898
            QA   SDYS  +F++L++LLL HG   Y R+   + YFFYKN  F L  F + FFCGFS 
Sbjct: 843  QAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQ 902

Query: 899  QTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFIC 958
            Q +YD  ++T++NI +TSLP+LA  + +Q ++       P+LY     N +     F   
Sbjct: 903  QPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYW 962

Query: 959  VLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWT 1018
                 +   V FF  Y  F   + E+   +    +F   + T LV  V++++ALDT +WT
Sbjct: 963  TFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWT 1022

Query: 1019 FINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVAS 1078
            +INH  IWGS+A Y  + F+    GI   F  Q          L+    WL I+L    S
Sbjct: 1023 WINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080

Query: 1079 VMPVVAFRFLK 1089
            + P +    LK
Sbjct: 1081 LFPEILLIVLK 1091


>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
           sapiens]
          Length = 387

 Score =  555 bits (1431), Expect = e-158
 Identities = 281/408 (68%), Positives = 326/408 (79%), Gaps = 25/408 (6%)

Query: 3   CSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLC 62
           C++K+  E ER  +ANDREYNEKFQYA N I TSKYNILTFLP+NLFEQFQ VAN YFL 
Sbjct: 4   CAKKRPPEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLF 63

Query: 63  LLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKL 122
           LLILQLIP+ISSL+WFTTIVPLVLV+T+TAVKDATDDYFRHKSDNQVNNRQS+VLIN  L
Sbjct: 64  LLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGIL 123

Query: 123 QNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVT 182
           Q E+WMNV VGDIIKLENNQFVAADLLLLSSSEPHGLCY+ETAELDGETN+KVR A+ VT
Sbjct: 124 QQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVT 183

Query: 183 SELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWC 242
           SELG DIS+LA FDG V+CE PNNKLDKF G L WK++K  L+N+ ++LRGC+LRNT WC
Sbjct: 184 SELG-DISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWC 242

Query: 243 FGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQT 302
           FG+VIFAGPDTKLMQNSG+TKFKRTSIDRLMNTLVLWIFGFL+C+G+ILAIGN+IWE + 
Sbjct: 243 FGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEV 302

Query: 303 GDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRK 362
           G +F+ +L W+E   S+ FSGFL+FWSYIIILNTVVPISLYV                  
Sbjct: 303 GMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYV------------------ 344

Query: 363 MYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSIN 410
                + +P++    +  E  G IE  FS K  +L  N  +   C++N
Sbjct: 345 -----RYVPSLTWGLS-RESGGPIELFFSMKMKSLRSNEKSSSSCTVN 386


>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
          Length = 1147

 Score =  425 bits (1092), Expect = e-118
 Identities = 336/1127 (29%), Positives = 545/1127 (48%), Gaps = 129/1127 (11%)

Query: 3    CSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLC 62
            C  KK  +   +      +  EK  +  N I   KYN+ TF+P  L+EQF+   N YFL 
Sbjct: 107  CRRKKELKARTVWLGCPEKCEEK--HPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLV 164

Query: 63   LLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNR-QSEVLINSK 121
            +   Q +P +     +T   PL  V+ +T  ++A D++ R + D +VN++  S++ +  K
Sbjct: 165  ISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGK 224

Query: 122  LQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSV 181
            +Q  K  +++VGD+I +E NQ + +D++ L +SE  G C++ T +LDGET+ K++ A+S 
Sbjct: 225  VQ-VKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSC 283

Query: 182  TSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSK----HSLNNEKIILRGCILR 237
            T +L A +  L      V  + P   +  F G  + +DS      SL+ E  +    I+ 
Sbjct: 284  TQQLPA-LGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVA 342

Query: 238  NTSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSI 297
            + +   G+VI+ G +T+ + N+   K K   +D  +N L   +F  L+ L I++      
Sbjct: 343  SGT-VIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVT---- 397

Query: 298  WESQTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFI 357
             +   G  +R                FL  +SYII      PISL V++++ +  + + +
Sbjct: 398  LQGFVGPWYRNLF------------RFLLLFSYII------PISLRVNLDMGKAVYGWMM 439

Query: 358  NWDRKMYYSRKAIPA-VARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGE 416
              D         IP  V RT+T+ EELG++ Y+ +DKTGTLTQN M FKR  +    YG 
Sbjct: 440  MKDEN-------IPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGA 492

Query: 417  VHDDLDQKTEITQEKEPVDFSVKSQAD---------REFQFFDHHLMESIKMGDPKVHEF 467
                 D   EI          ++SQA          R+ Q     + +S+     ++HE 
Sbjct: 493  -----DTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSS---RIHEA 544

Query: 468  LRLLALCHTV---------MSEENSAGEL---------IYQVQSPDEGALVTAARNFGFI 509
            ++ + LCH V         ++EE    E           YQ  SPDE ALV    + G  
Sbjct: 545  VKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLT 604

Query: 510  FKSRTPETITIEE-LGTLVTYQLLAFLDFNNTRKRMSVIVRNPE-GQIKLYSKGADTILF 567
              SR   ++ ++   G ++++ +L    F +  KRM VIVR+    +I  Y KGAD +  
Sbjct: 605  LVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD-VAM 663

Query: 568  EKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDE 627
              +   N+ L     +     A EGLRTL +A + L ++ ++++      A  +  +R  
Sbjct: 664  SPIVQYNDWL----EEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSL 719

Query: 628  RIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYA 687
            ++A + E +ER++ LL  T VED+LQ  V  T+  L  A IKIW+LTGDK ETA  I  +
Sbjct: 720  KVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKS 779

Query: 688  CNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVE 747
             ++++                     R    ++F Q  +    H        LEL++   
Sbjct: 780  SHLVS---------------------RTQDIHIFRQVTSRGEAH--------LELNAFRR 810

Query: 748  ETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRN 807
            +    D AL+I+G SL   L+   +++ +ELAC C  V+CCR +P QKA++V L++++  
Sbjct: 811  KH---DCALVISGDSLEVCLKY-YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTG 866

Query: 808  AVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYF 867
              T AIGDG NDVSMI++A  G+GI G+EG QA LA+D+S  QFR++ RLL+VHGR SY 
Sbjct: 867  RRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYK 926

Query: 868  RMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQ 927
            R      +  ++    + +   F     F++  +Y  + +  +  +YT  PV ++ + DQ
Sbjct: 927  RSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQ 985

Query: 928  DVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQH 987
            DV  + ++  P+LYK        + + F I VL  IY   +L    YGA      E    
Sbjct: 986  DVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILM---YGALVLFESE---- 1038

Query: 988  IADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGI 1047
               +        T+L++   + +AL    W ++  V  + S+  Y S L  +  N  FGI
Sbjct: 1039 ---FVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFL--NEYFGI 1093

Query: 1048 FPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYP 1094
                F    +     T   +W V  + TV S +P+   ++L+  L P
Sbjct: 1094 GRVSFGAFLDVAFITTVTFLWKVSAI-TVVSCLPLYVLKYLRRKLSP 1139


>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
          Length = 1499

 Score =  424 bits (1091), Expect = e-118
 Identities = 251/654 (38%), Positives = 388/654 (59%), Gaps = 36/654 (5%)

Query: 480  EENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIE--ELGTLVTYQLLAFLDF 537
            E+ S  EL Y+ +SPDE ALV AAR +  +   R  + +++E   LG L T++LL  L F
Sbjct: 684  EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRL-TFELLHTLGF 742

Query: 538  NNTRKRMSVIVRNP-EGQIKLYSKGADTILFEKLHPSNEV---------LLSLTSDHLSE 587
            ++ RKRMSV++R+P   +I +Y+KGAD+++ + L P + V         + S T ++L+ 
Sbjct: 743  DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802

Query: 588  FAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATA 647
            +A EGLRTL IA R L  + +  W +   +A ++ E  +E +      +E +L LLGAT 
Sbjct: 803  YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862

Query: 648  VEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAV 707
            +ED+LQ+GV ET++ L  A ++IWVLTGDKQETA+NI YAC +L  D   + +    NA 
Sbjct: 863  IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL----NAT 918

Query: 708  EVREELRKAKQNL-FGQNRNFSNGHVVCEKKQQLELDSIVE---ETITGDY-ALIINGHS 762
                      Q L + Q+R         + K  +   S+      T +G   +L+I+G S
Sbjct: 919  SQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRS 978

Query: 763  LAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSM 822
            LA+ALE ++++  L LA  C++V+CCR TPLQK+ VV+LV+    A+TLAIGDGANDVSM
Sbjct: 979  LAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSM 1038

Query: 823  IKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFA 882
            I+ A +GVGISGQEG+QAV+ASD++  +FRYL+RLL++HG W Y R+   + YFFYKN  
Sbjct: 1039 IQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTM 1098

Query: 883  FTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYK 942
            F  + FWF FFCGFSA T+ DQW++  FN++++SLP L  G+ D+DV     +  PQLYK
Sbjct: 1099 FVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYK 1158

Query: 943  PGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSL 1002
             GQ    +  R F+  +    + SLV F IPY A+Y+          D  ++   + T  
Sbjct: 1159 SGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYD-------SNVDLFTWGTPIVTIA 1211

Query: 1003 VIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSL 1062
            ++   + + ++T  WT++N +    S+ ++F++   +++      +P   P+    +  L
Sbjct: 1212 LLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVAL-IYNASCATCYPPSNPY-WTMQALL 1269

Query: 1063 TQKCIWLVILLTTVASVMPVVAFRFLKVDLYPT---LSDQIRRWQKAQKKARPP 1113
                 +L  L+T VA+++P + FR L+  ++PT   L+ Q+ R  K+ ++   P
Sbjct: 1270 GDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTR--KSPRRCSAP 1321



 Score =  311 bits (796), Expect = 3e-84
 Identities = 167/411 (40%), Positives = 252/411 (61%), Gaps = 12/411 (2%)

Query: 29  ADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVLVI 88
           ADNR+ T+KY +L+FLP NLFEQF R AN YF+ + +L  +P +++      + P++ ++
Sbjct: 60  ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFIL 119

Query: 89  TMTAVKDATDDYFRHKSDNQVNNRQSEVLINS--KLQNEKWMNVKVGDIIKLENNQFVAA 146
            +TA +D  +DY RH+SD+++N+    V      K  N  W  + VGD ++L  N+   A
Sbjct: 120 AITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPA 179

Query: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
           D+LLLSSS+P GLC++ETA LDGETNLK R  +   SEL ++ + L  F  ++ CE PNN
Sbjct: 180 DILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLT-FTSVIECEKPNN 238

Query: 207 KLDKFMG-ILSWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
            L +F G I+     K  L  E ++LRGC LRNT    G+VI+AG +TK + N+   ++K
Sbjct: 239 DLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYK 298

Query: 266 RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFW---NEGEK-SSVF 321
           R+ ++R MN  VLW    L+C+ +  A+G+ +W  +   Q +  LF+   ++G   S V 
Sbjct: 299 RSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRY--QEKKSLFYVPKSDGSSLSPVT 356

Query: 322 SGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNE 381
           +   +F + II+L  ++PISLYVS+E+++    YFIN D ++Y          R   + E
Sbjct: 357 AAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITE 416

Query: 382 ELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKE 432
           +LGQI+YIFSDKTGTLT+N M F+RC+++G  Y   HD   Q+    QE +
Sbjct: 417 DLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYS--HDANAQRLARYQEAD 465


>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
          Length = 1461

 Score =  424 bits (1091), Expect = e-118
 Identities = 249/705 (35%), Positives = 388/705 (55%), Gaps = 50/705 (7%)

Query: 486  ELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIE-ELGTLVTYQLLAFLDFNNTRKRM 544
            E  Y+ +SPDE ALV AA  + F   SRTPE +T+    GT +T+ LL  L F++ RKRM
Sbjct: 714  EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773

Query: 545  SVIVRNP-EGQIKLYSKGADTILFEKLHPSNEV-----------LLSLTSDHLSEFAGEG 592
            SV+VR+P  G+I +Y+KGAD+++ + L     V           + + T  HL  +A +G
Sbjct: 774  SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833

Query: 593  LRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKL 652
            LRTL IA + + ++ F+ W     +A A+ + RDE +    + +E  L LLGAT +ED+L
Sbjct: 834  LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893

Query: 653  QEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREE 712
            QEGV +T+ +L  A I++WVLTGDKQETA+NI ++C +L +  + V+ I   N       
Sbjct: 894  QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLL-NQTDTVYTINTENQETCESI 952

Query: 713  LRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVK 772
            L  A + L            +   +   +  SI  E +  +  L+I+G +L    +  ++
Sbjct: 953  LNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLE 1012

Query: 773  NDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGI 832
               LEL   C++V+CCR TPLQK+ +V+LV+     +TL+IGDGANDVSMI++A IG+GI
Sbjct: 1013 KKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGI 1072

Query: 833  SGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGF 892
            SGQEG+QAV++SD++  +F++L++LLLVHG W Y R+ + + Y+ YKN  +  + FW+ F
Sbjct: 1073 SGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQF 1132

Query: 893  FCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNK 952
            FCGFS+ T+ D W +  FN+ +TSLP L  G+ D+D+S +  +  P+LYK GQ +  +N 
Sbjct: 1133 FCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNL 1192

Query: 953  RKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIAL 1012
              F+I ++   Y SL+ FFIPY A+    G D     D  +F   + T  +  + +  A+
Sbjct: 1193 STFWISMVDAFYQSLICFFIPYLAY---KGSD----IDVFTFGTPINTISLTTILLHQAM 1245

Query: 1013 DTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVIL 1072
            +   WT  + V + GS  +YF +    ++  +    P    +V   +  L+    +LV  
Sbjct: 1246 EMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQ--LSNPTFYLVCF 1303

Query: 1073 LTTVASVMPVVAFRFL-------------KVDLYP--TLSDQIRRWQKAQKKARPPSSRR 1117
            LT V +++P   F  L             K+D  P    + +I+ W+  Q+ A  P   R
Sbjct: 1304 LTPVVALLPRYFFLSLQGTCGKSLISKAQKIDKLPPDKRNLEIQSWRSRQRPAPVPEVAR 1363

Query: 1118 PRTRRSSSRRSGYAFAHQEGYGELITSGKNMRAKNPPPTSGLEKT 1162
            P T    S  +G  F           S    ++ NPP    +E++
Sbjct: 1364 P-THHPVSSITGQDF-----------SASTPKSSNPPKRKHVEES 1396



 Score =  294 bits (753), Expect = 3e-79
 Identities = 170/450 (37%), Positives = 258/450 (57%), Gaps = 20/450 (4%)

Query: 12  ERIVKANDREYNEKFQ-----YADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLIL 66
           +R+V  N+  +++ ++     Y  NR  T+KY + TFLP NLFEQF R AN YFL L+IL
Sbjct: 45  QRVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVIL 104

Query: 67  QLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQ--N 124
             +P +       T++PL +V+ +  +KD  +D+ RH+ D  +N     +    +     
Sbjct: 105 NWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQ 164

Query: 125 EKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSE 184
           + W +V+VGD I+++ N+ V AD+LLL SS+P+G+C++ETA LDGETNLK R  +   S+
Sbjct: 165 KCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQ 224

Query: 185 LGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKD-SKHSLNNEKIILRGCILRNTSWCF 243
                     F   +VCE PNN L+KF G +   D ++     E ++LRGC +RNT    
Sbjct: 225 QEVQFEPEL-FHNTIVCEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAV 283

Query: 244 GMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTG 303
           G+VI+AG +TK M N+   ++KR+ I+R MN  + +  G LI + +I A+G+SIW   T 
Sbjct: 284 GIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG-TF 342

Query: 304 DQFRTFLF--WNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDR 361
           ++   F     N     S   GF  F + II+L  ++PISLYVS+E+++LG  +F++ D 
Sbjct: 343 EEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDL 402

Query: 362 KMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYG------ 415
            +Y     +    R   + E+LGQI+YIFSDKTGTLT+N M F+RC+I G  Y       
Sbjct: 403 DLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAK 462

Query: 416 --EVHDDLDQKTEITQEKEPVDFSVKSQAD 443
             E   +LD   E   + + + FS +   D
Sbjct: 463 RLETPKELDSDGEEWTQYQCLSFSARWAQD 492


>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
          Length = 1426

 Score =  421 bits (1083), Expect = e-117
 Identities = 256/704 (36%), Positives = 401/704 (56%), Gaps = 70/704 (9%)

Query: 484  AGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIE--ELGTLVTYQLLAFLDFNNTR 541
            A  L Y+ +SPDE ALV AAR +    +SRTPE + ++   LG L T+QLL  L F++ R
Sbjct: 718  ACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPL-TFQLLHILPFDSVR 776

Query: 542  KRMSVIVRNP-EGQIKLYSKGADTILFE----------KLHPSNEVLLSLTSDHLSEFAG 590
            KRMSV+VR+P   Q+ +Y+KGAD+++ E           L     ++   T  HL ++A 
Sbjct: 777  KRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAK 836

Query: 591  EGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVED 650
            +GLRTL IA + + D  + EW +    A  + + R+E +      +E  L LLGAT +ED
Sbjct: 837  QGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIED 896

Query: 651  KLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVI-------AG 703
            +LQEGV E++ +L  A IKIW+LTGDKQETA+NI YAC +L  D + +F++        G
Sbjct: 897  RLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPD-DKLFILNTQSKDACG 955

Query: 704  NNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLEL-DSIVEETITGDYAL----II 758
                 + +EL+K  Q L                 +Q+ L + +++  +  D  L    II
Sbjct: 956  MLMSTILKELQKKTQAL----------------PEQVSLSEDLLQPPVPRDSGLRAGLII 999

Query: 759  NGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGAN 818
             G +L  AL+  ++   LEL   C+ V+CCR TPLQK++VV+LV+ +   +TLAIGDGAN
Sbjct: 1000 TGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGAN 1059

Query: 819  DVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFY 878
            DVSMI+ A IG+G+SGQEG+QAV+ASD++ +QF++L +LLLVHG W Y R+   + YFFY
Sbjct: 1060 DVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFY 1119

Query: 879  KNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCP 938
            KN A+  + FW+ FFCGFS  ++ D W +  FN+++TS P +  G+ ++DVS +  +  P
Sbjct: 1120 KNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLP 1179

Query: 939  QLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTM 998
            +LY+ GQ +  +    F+I +L   Y SLV FF+PY   +   G D     D  +F   +
Sbjct: 1180 ELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPY---FTYQGSD----TDIFAFGNPL 1232

Query: 999  ATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIF-----PNQFP 1053
             T+ + +V + + +++   T+I+ + I GSI  YF  LF +    +FG       P   P
Sbjct: 1233 NTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYF--LFAI----VFGAMCVTCNPPSNP 1286

Query: 1054 FVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPP 1113
            +     H L     +LV +LTT  +++P   +R L+  L+P+   + + + +   + R  
Sbjct: 1287 YWIMQEHML-DPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILRAKHFDRLTPEERTK 1345

Query: 1114 SSRRPRTRRSSSRRSGYAFAHQEGYGELITSGKNMRAKNPPPTS 1157
            + ++ R     ++ +   +A+Q       ++GK+ R   P P++
Sbjct: 1346 ALKKWRGAGKMNQVTS-KYANQ-------SAGKSGRRPMPGPSA 1381



 Score =  315 bits (806), Expect = 2e-85
 Identities = 173/445 (38%), Positives = 268/445 (60%), Gaps = 22/445 (4%)

Query: 7   KLREVERIVKANDREYNEKFQ-----YADNRIHTSKYNILTFLPINLFEQFQRVANAYFL 61
           KL    RIV  + + + ++++     Y +NRI T+KY +L F+P NLFEQF R AN YFL
Sbjct: 45  KLSGRHRIVVPHIQPFKDEYEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFL 104

Query: 62  CLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINS- 120
            L++L  +P + +     T++PLV+V+T+ A+KD  +DY ++K D Q+NN  ++V     
Sbjct: 105 FLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKE 164

Query: 121 -KLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHAL 179
            K  +  W +V VGD I+L  N+ + AD++LL S++P G+C++ET+ LDGE+NLK R  +
Sbjct: 165 KKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVV 224

Query: 180 SVTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKH-SLNNEKIILRGCILRN 238
              +E  +++     F   + CE PNN L +F G L   + +   L+ E ++LRGC +RN
Sbjct: 225 RGYAEQDSEVDP-EKFSSRIECESPNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRN 283

Query: 239 TSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIW 298
           T    G+V++AG +TK M N+   ++KR+ ++R  NT VLW    L+ + +  A+G+ IW
Sbjct: 284 TEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIW 343

Query: 299 ESQTGDQFRTFLFWNEGEK-----SSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGH 353
            S+    +    F+N  E      S + +GF  FW+ II+L  ++PISLYVS+E+++LG 
Sbjct: 344 LSR----YEKMHFFNVPEPDGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQ 399

Query: 354 SYFINWDRKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRI 413
            YFI  D   Y  +       R   + E+LGQI+Y+FSDKTGTLT+N M F+RCS+ G  
Sbjct: 400 IYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFD 459

Query: 414 YGEVHDDLDQKTEITQE--KEPVDF 436
           Y   H++  ++ E  QE   E  DF
Sbjct: 460 Y--CHEENARRLESYQEAVSEDEDF 482


>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
          Length = 1047

 Score =  421 bits (1083), Expect = e-117
 Identities = 317/1090 (29%), Positives = 527/1090 (48%), Gaps = 134/1090 (12%)

Query: 27   QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
            +Y  N I+  KYN  TFLP  LF QF+   N YFL L   Q +PE+     +T  VPL  
Sbjct: 52   RYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGF 111

Query: 87   VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
            V+ +T +++A ++   +  D +VN++    L        K  N++VGD+I +E NQ V A
Sbjct: 112  VLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPA 171

Query: 147  DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSEL--GADISRLAGFDGIVVCEVP 204
            D++ L +SE +G C++ T +LDGET+ K+R  ++ T  L   AD+ ++  +   V  E P
Sbjct: 172  DMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSY---VYAEEP 228

Query: 205  NNKLDKFMGILSWKDS----KHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSG 260
            N  +  F+G  + +DS      SL+ E  +  G ++ + +   G+V++ G + + + N+ 
Sbjct: 229  NIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTS 287

Query: 261  KTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSV 320
              + K    D  +N L   +FG L+ + +++                             
Sbjct: 288  NPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQH------------------------ 323

Query: 321  FSG--FLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPA-VARTT 377
            F+G  +L    ++++ + ++PISL V++++ ++ +S+ I  D K       IP  V R++
Sbjct: 324  FAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSK-------IPGTVVRSS 376

Query: 378  TLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFS 437
            T+ E+LG+I Y+ +DKTGTLTQN M FKR  +    YG     LD   E+        FS
Sbjct: 377  TIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYG-----LDSMDEVQSHI----FS 427

Query: 438  VKSQADRE--FQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGEL-------- 487
            + +Q  ++   Q       +  +    +VHE ++ +ALCH V     S G          
Sbjct: 428  IYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQ 487

Query: 488  ------IYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGT-LVTYQLLAFLDFNNT 540
                  +YQ  SPDE ALV    + G     R   ++ +   G  ++ + +L    F   
Sbjct: 488  YEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYE 547

Query: 541  RKRMSVIVRNPE-GQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIA 599
             KRM +IVR+   G+I  Y KGAD ++   +  ++ +      +     A EGLR L +A
Sbjct: 548  SKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWL-----EEECGNMAREGLRVLVVA 602

Query: 600  YRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIET 659
             + L ++ ++++      A  +  +R  ++A + E +E ++ LL  T VED+LQ  V  T
Sbjct: 603  KKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPT 662

Query: 660  VTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQN 719
            + +L  A IK+W+LTGDK ETA       +++T                     R    +
Sbjct: 663  LETLRNAGIKVWMLTGDKLETATCTAKNAHLVT---------------------RNQDIH 701

Query: 720  LFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELA 779
            +F    N    H        LEL++   +    D AL+I+G SL   L+   + + +ELA
Sbjct: 702  VFRLVTNRGEAH--------LELNAFRRKH---DCALVISGDSLEVCLKY-YEYEFMELA 749

Query: 780  CMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQ 839
            C C  V+CCR  P QKAQ+V L+++    +T A+GDG NDVSMI+ +  GVG+ G+EG Q
Sbjct: 750  CQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQ 809

Query: 840  AVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQ 899
            A LA+D+S  QF++L RLL+VHGR SY R      +  +++   + +   F     F++ 
Sbjct: 810  ASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASV 869

Query: 900  TVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICV 959
             +Y  + I  ++ +YT  PV ++ + D+DV  + ++  P+LYK        + + F I V
Sbjct: 870  PLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWV 928

Query: 960  LHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTF 1019
            L  IY       I YGA      E       +        TSL++   + +AL    W +
Sbjct: 929  LISIYQGST---IMYGALLLFESE-------FVHIVAISFTSLILTELLMVALTIQTWHW 978

Query: 1020 INHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASV 1079
            +  V    S+A Y + L  +H             F+ +     T   +W V ++T V S 
Sbjct: 979  LMTVAELLSLACYIASLVFLHE------------FI-DVYFIATLSFLWKVSVITLV-SC 1024

Query: 1080 MPVVAFRFLK 1089
            +P+   ++L+
Sbjct: 1025 LPLYVLKYLR 1034


>gi|66932949 ATPase type 13A4 [Homo sapiens]
          Length = 1196

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 84/329 (25%), Positives = 150/329 (45%), Gaps = 47/329 (14%)

Query: 513 RTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHP 572
           RT   + +E +  L  +       F++  +RM+VIV+   G    + KGA   +     P
Sbjct: 583 RTASQVPVEGIAILHQFP------FSSALQRMTVIVQEMGGDRLAFMKGAPERVASFCQP 636

Query: 573 SNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGL 632
              V  S  S+ L  +  +G R +A+AY+ L++           D +A T  R       
Sbjct: 637 ET-VPTSFVSE-LQIYTTQGFRVIALAYKKLEN-----------DHHATTLTR------- 676

Query: 633 YEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLT 692
            E +E DL+ LG   +E++L+E     +  L  A I+  ++TGD  +TAI +     M++
Sbjct: 677 -ETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVS 735

Query: 693 DDMNDVFVIA----GNNAVEVREELRKAKQN-LFGQNRNFSNGHVVCEKKQQLELDSIVE 747
           +    + + A    G+++  +   L + K++ ++G   N+ N             D + +
Sbjct: 736 ESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIR-----------DEVSD 784

Query: 748 ETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRN 807
           +   G Y   + G S  H +     + L ++  +    I  R++P QK+ +VE  +K   
Sbjct: 785 KGREGSYHFALTGKSF-HVISQHFSSLLPKI--LINGTIFARMSPGQKSSLVEEFQKLDY 841

Query: 808 AVTLAIGDGANDVSMIKSAHIGVGISGQE 836
            V +  GDGAND   +K AH+G+ +S QE
Sbjct: 842 FVGMC-GDGANDCGALKMAHVGISLSEQE 869


>gi|148839292 ATPase type 13A3 [Homo sapiens]
          Length = 1226

 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 81/320 (25%), Positives = 144/320 (45%), Gaps = 44/320 (13%)

Query: 537 FNNTRKRMSVIVRN-PEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRT 595
           F++  +RMSV+ R   + ++  Y KGA   +     P  E +     + L +F  +G R 
Sbjct: 628 FSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKP--ETVPVDFQNVLEDFTKQGFRV 685

Query: 596 LAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEG 655
           +A+A+R L+ K    WHK+   +  A              IE ++  +G   +++KL++ 
Sbjct: 686 IALAHRKLESKL--TWHKVQNISRDA--------------IENNMDFMGLIIMQNKLKQE 729

Query: 656 VIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRK 715
               +  L  ANI+  ++TGD   TA+++   C M          I   + V + E L  
Sbjct: 730 TPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGM----------ILPQDKVIIAEALPP 779

Query: 716 AKQNLFGQNRNFSNGHVVCEKKQQLELDSI--------VEETITGDYALIINGHSLAHAL 767
               +   N ++++    C     ++ ++I        +E+     Y   +NG S +  L
Sbjct: 780 KDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVIL 839

Query: 768 ESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAH 827
           E     DL+    +  TV   R+ P QK Q++E ++     V +  GDGAND   +K AH
Sbjct: 840 EH--FQDLVPKLMLHGTVF-ARMAPDQKTQLIEALQNVDYFVGMC-GDGANDCGALKRAH 895

Query: 828 IGVGISGQEGLQAVLASDYS 847
            G+ +S    L+A +AS ++
Sbjct: 896 GGISLS---ELEASVASPFT 912


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
           sapiens]
          Length = 1170

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 123/524 (23%), Positives = 187/524 (35%), Gaps = 134/524 (25%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  I G  Y ++                 D  +  
Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSP--------------DVFLPK 499

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
             D         ++  I +            A    ++  E   G L  QV +  E AL+
Sbjct: 500 VLDL--------IVNGISINS----------AYTSKILPPEKEGG-LPRQVGNKTECALL 540

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 GF+   +        E+     Y++  F   N+ RK MS ++RNP G  ++YSK
Sbjct: 541 ------GFVTDLKQDYQAVRNEVPEEKLYKVYTF---NSVRKSMSTVIRNPNGGFRMYSK 591

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  I+  K    L    E +     D        +   A +GLRT+ IAYRD DD    
Sbjct: 592 GASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE-P 650

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
            W                       EI  +L  +    +ED ++  V + +     A I 
Sbjct: 651 SWDN-------------------ENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGIT 691

Query: 670 IWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSN 729
           + ++TGD   TA  I   C +LT   +D   + G    E    +R  K            
Sbjct: 692 VRMVTGDNINTARAIATKCGILTPG-DDFLCLEGK---EFNRLIRNEK------------ 735

Query: 730 GHVVCEKKQQL--ELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVIC 787
           G V  EK  ++  +L  +   + T  + L+                              
Sbjct: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLV------------------------------ 765

Query: 788 CRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIG--VGISGQEGLQAVLASD 845
                  K  +   V ++R  V +  GDG ND   +K A +G  +GI+G +   A  ASD
Sbjct: 766 -------KGIIDSTVGEHRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASD 815

Query: 846 YSFAQFRYLQRL-LLVHGRWSYFRMCKFLCYFFYKNFAFTLVHF 888
                  +   +  ++ GR  Y  + KFL +    N    +V F
Sbjct: 816 IILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 859


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
           sapiens]
          Length = 1205

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 123/524 (23%), Positives = 187/524 (35%), Gaps = 134/524 (25%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  I G  Y ++                 D  +  
Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSP--------------DVFLPK 499

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
             D         ++  I +            A    ++  E   G L  QV +  E AL+
Sbjct: 500 VLDL--------IVNGISINS----------AYTSKILPPEKEGG-LPRQVGNKTECALL 540

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 GF+   +        E+     Y++  F   N+ RK MS ++RNP G  ++YSK
Sbjct: 541 ------GFVTDLKQDYQAVRNEVPEEKLYKVYTF---NSVRKSMSTVIRNPNGGFRMYSK 591

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  I+  K    L    E +     D        +   A +GLRT+ IAYRD DD    
Sbjct: 592 GASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE-P 650

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
            W                       EI  +L  +    +ED ++  V + +     A I 
Sbjct: 651 SWDN-------------------ENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGIT 691

Query: 670 IWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSN 729
           + ++TGD   TA  I   C +LT   +D   + G    E    +R  K            
Sbjct: 692 VRMVTGDNINTARAIATKCGILTPG-DDFLCLEGK---EFNRLIRNEK------------ 735

Query: 730 GHVVCEKKQQL--ELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVIC 787
           G V  EK  ++  +L  +   + T  + L+                              
Sbjct: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLV------------------------------ 765

Query: 788 CRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIG--VGISGQEGLQAVLASD 845
                  K  +   V ++R  V +  GDG ND   +K A +G  +GI+G +   A  ASD
Sbjct: 766 -------KGIIDSTVGEHRQVVAVT-GDGTNDGPALKKADVGFAMGIAGTD--VAKEASD 815

Query: 846 YSFAQFRYLQRL-LLVHGRWSYFRMCKFLCYFFYKNFAFTLVHF 888
                  +   +  ++ GR  Y  + KFL +    N    +V F
Sbjct: 816 IILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 859


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
           sapiens]
          Length = 1220

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 81/322 (25%), Positives = 125/322 (38%), Gaps = 72/322 (22%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  +    Y E+               P   ++  
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEI---------------PAPSALTP 506

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
                            K+ D  VH      A    ++  E   G L  QV +  E AL+
Sbjct: 507 -----------------KILDLLVHAISINSAYTTKILPPEKE-GALPRQVGNKTECALL 548

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 GF+   +       E++     Y++  F   N+ RK MS ++R P+G  +L+SK
Sbjct: 549 ------GFVLDLKRDFQPVREQIPEDKLYKVYTF---NSVRKSMSTVIRMPDGGFRLFSK 599

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  IL +K    L+ + E+      D        +   A +GLRT+ IAYRD       
Sbjct: 600 GASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEP 659

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
           +W            + +  + G       DL  +    +ED ++  V E +     A I 
Sbjct: 660 DW------------DNENEVVG-------DLTCIAVVGIEDPVRPEVPEAIRKCQRAGIT 700

Query: 670 IWVLTGDKQETAINIGYACNML 691
           + ++TGD   TA  I   C ++
Sbjct: 701 VRMVTGDNINTARAIAAKCGII 722


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
           sapiens]
          Length = 1173

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 81/322 (25%), Positives = 125/322 (38%), Gaps = 72/322 (22%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  +    Y E+               P   ++  
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEI---------------PAPSALTP 506

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
                            K+ D  VH      A    ++  E   G L  QV +  E AL+
Sbjct: 507 -----------------KILDLLVHAISINSAYTTKILPPEKE-GALPRQVGNKTECALL 548

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 GF+   +       E++     Y++  F   N+ RK MS ++R P+G  +L+SK
Sbjct: 549 ------GFVLDLKRDFQPVREQIPEDKLYKVYTF---NSVRKSMSTVIRMPDGGFRLFSK 599

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  IL +K    L+ + E+      D        +   A +GLRT+ IAYRD       
Sbjct: 600 GASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEP 659

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
           +W            + +  + G       DL  +    +ED ++  V E +     A I 
Sbjct: 660 DW------------DNENEVVG-------DLTCIAVVGIEDPVRPEVPEAIRKCQRAGIT 700

Query: 670 IWVLTGDKQETAINIGYACNML 691
           + ++TGD   TA  I   C ++
Sbjct: 701 VRMVTGDNINTARAIAAKCGII 722


>gi|66730421 ATPase type 13A5 [Homo sapiens]
          Length = 1218

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 92/363 (25%), Positives = 162/363 (44%), Gaps = 47/363 (12%)

Query: 537 FNNTRKRMSVIVRNP-EGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRT 595
           F+++ +RMSVI +   E    +Y KGA  ++       +E +       L  +  +G R 
Sbjct: 600 FSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCR--SETVPKNFPQELRSYTVQGFRV 657

Query: 596 LAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEG 655
           +A+A            HK L+  N +  E   R     E++E +L  LG   +E++L++ 
Sbjct: 658 IALA------------HKTLKMGNLSEVEHLAR-----EKVESELTFLGLLIMENRLKKE 700

Query: 656 VIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRK 715
               +  LS A I+  ++TGD  +TAI +     M+      + V     A E  E +  
Sbjct: 701 TKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVIIV----EADEPEEFVPA 756

Query: 716 AKQNLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGD----YALIINGHSLAHALESDV 771
           +      +N+    G      K+++ + +    T  G+    Y   ++G S     +   
Sbjct: 757 SVTWQLVENQETGPG------KKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQVIFQH-- 808

Query: 772 KNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVG 831
            N LL    +  TV   R++P QK+ ++E  +K    V +  GDGAND   +K+AH G+ 
Sbjct: 809 FNSLLPKILVNGTVF-ARMSPGQKSSLIEEFQKLNYYVGMC-GDGANDCGALKAAHAGIS 866

Query: 832 ISGQEGLQAVLASDYSFAQFRYLQRL--LLVHGR---WSYFRMCKFLCYFFYKNFAFTLV 886
           +S QE   A +AS ++ ++   +Q +  L+  GR    S F + K+L  +    F   L+
Sbjct: 867 LSEQE---ASVASPFT-SKTTNIQCVPHLIREGRAALVSSFGVFKYLTMYGIIQFISALL 922

Query: 887 HFW 889
            +W
Sbjct: 923 LYW 925


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
           sapiens]
          Length = 1176

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 78/322 (24%), Positives = 124/322 (38%), Gaps = 71/322 (22%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  IN + Y +V            E E +  ++ S
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKV-----------PEPEAIPPNILS 512

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
                      +L+  I +            A    ++  E   G L   V +  E AL+
Sbjct: 513 -----------YLVTGISVN----------CAYTSKILPPEKEGG-LPRHVGNKTECALL 550

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 G +   +        E+     Y++  F   N+ RK MS +++N +G  +++SK
Sbjct: 551 ------GLLLDLKRDYQDVRNEIPEEALYKVYTF---NSVRKSMSTVLKNSDGSYRIFSK 601

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  I+ +K    L  + E  +    D        +   A EGLRT+ +A+RD       
Sbjct: 602 GASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDF------ 655

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
                   A     E D        +I   L  +    +ED ++  V + +     A I 
Sbjct: 656 -------PAGEPEPEWDNE-----NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGIT 703

Query: 670 IWVLTGDKQETAINIGYACNML 691
           + ++TGD   TA  I   C +L
Sbjct: 704 VRMVTGDNINTARAIATKCGIL 725


>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
           sapiens]
          Length = 1220

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 78/322 (24%), Positives = 124/322 (38%), Gaps = 71/322 (22%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  IN + Y +V            E E +  ++ S
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKV-----------PEPEAIPPNILS 512

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
                      +L+  I +            A    ++  E   G L   V +  E AL+
Sbjct: 513 -----------YLVTGISVN----------CAYTSKILPPEKEGG-LPRHVGNKTECALL 550

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 G +   +        E+     Y++  F   N+ RK MS +++N +G  +++SK
Sbjct: 551 ------GLLLDLKRDYQDVRNEIPEEALYKVYTF---NSVRKSMSTVLKNSDGSYRIFSK 601

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  I+ +K    L  + E  +    D        +   A EGLRT+ +A+RD       
Sbjct: 602 GASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDF------ 655

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
                   A     E D        +I   L  +    +ED ++  V + +     A I 
Sbjct: 656 -------PAGEPEPEWDNE-----NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGIT 703

Query: 670 IWVLTGDKQETAINIGYACNML 691
           + ++TGD   TA  I   C +L
Sbjct: 704 VRMVTGDNINTARAIATKCGIL 725


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 73/322 (22%), Positives = 120/322 (37%), Gaps = 72/322 (22%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  +    Y E+ D             P   + K+
Sbjct: 443 ETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPD-------------PSSINTKT 489

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
                       L+ +I +      + L                G L  QV +  E  L+
Sbjct: 490 M---------ELLINAIAINSAYTTKIL-----------PPEKEGALPRQVGNKTECGLL 529

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 GF+   +        ++     Y++  F   N+ RK MS +++ P+   ++YSK
Sbjct: 530 ------GFVLDLKQDYEPVRSQMPEEKLYKVYTF---NSVRKSMSTVIKLPDESFRMYSK 580

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  I+ +K    L+ + E  +    D        +   A +GLRT+ +AYRD       
Sbjct: 581 GASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEP 640

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
           +W                       +I  +L  +    +ED ++  V E +     A I 
Sbjct: 641 DWDN-------------------ENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGIT 681

Query: 670 IWVLTGDKQETAINIGYACNML 691
           + ++TGD   TA  I   C ++
Sbjct: 682 VRMVTGDNINTARAIAIKCGII 703


>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
           sapiens]
          Length = 1243

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 73/322 (22%), Positives = 120/322 (37%), Gaps = 72/322 (22%)

Query: 381 EELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKS 440
           E +G    I SDKTGTLT N MT  +  +    Y E+ D             P   + K+
Sbjct: 488 ETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPD-------------PSSINTKT 534

Query: 441 QADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALV 500
                       L+ +I +      + L                G L  QV +  E  L+
Sbjct: 535 M---------ELLINAIAINSAYTTKIL-----------PPEKEGALPRQVGNKTECGLL 574

Query: 501 TAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSK 560
                 GF+   +        ++     Y++  F   N+ RK MS +++ P+   ++YSK
Sbjct: 575 ------GFVLDLKQDYEPVRSQMPEEKLYKVYTF---NSVRKSMSTVIKLPDESFRMYSK 625

Query: 561 GADTILFEK----LHPSNEVLLSLTSDH-------LSEFAGEGLRTLAIAYRDLDDKYFK 609
           GA  I+ +K    L+ + E  +    D        +   A +GLRT+ +AYRD       
Sbjct: 626 GASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEP 685

Query: 610 EWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIK 669
           +W                       +I  +L  +    +ED ++  V E +     A I 
Sbjct: 686 DWDN-------------------ENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGIT 726

Query: 670 IWVLTGDKQETAINIGYACNML 691
           + ++TGD   TA  I   C ++
Sbjct: 727 VRMVTGDNINTARAIAIKCGII 748


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
           sapiens]
          Length = 997

 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 140/644 (21%), Positives = 231/644 (35%), Gaps = 129/644 (20%)

Query: 372 AVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEK 431
           A+ R+    E LG    I SDKTGTLT N M+  R  I  R+ G+    L++ T      
Sbjct: 331 AIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDT-CSLNEFTITGSTY 389

Query: 432 EPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQV 491
            P+      +  ++ +  + H  + +        E   + ALC+    + N A  +  +V
Sbjct: 390 API-----GEVHKDDKPVNCHQYDGLV-------ELATICALCNDSALDYNEAKGVYEKV 437

Query: 492 QSPDEGALVTAARNFGFIFKSRTPETITIEELGTL--VTYQLLA---FLDFNNTRKRMSV 546
               E AL         +F +       IE       V  QL+     L+F+  RK MSV
Sbjct: 438 GEATETALTCLVEKMN-VFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSV 496

Query: 547 IVR----NPEGQIKLYSKGADTILFEKLH---------PSNEVLLSLTSDHLSEF--AGE 591
                  +     K++ KGA   + ++           P    +       + E+    +
Sbjct: 497 YCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSD 556

Query: 592 GLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDK 651
            LR LA+A  D +    +E H  LED            +  + + E +L  +G   + D 
Sbjct: 557 TLRCLALATHD-NPLRREEMH--LED------------SANFIKYETNLTFVGCVGMLDP 601

Query: 652 LQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVRE 711
            +  V  +V     A I++ ++TGD + TA+ I   C  +                    
Sbjct: 602 PRIEVASSVKLCRQAGIRVIMITGDNKGTAVAI---CRRI-------------------- 638

Query: 712 ELRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDV 771
                   +FGQ+                  + +  +  TG               E D 
Sbjct: 639 -------GIFGQD------------------EDVTSKAFTG--------------REFDE 659

Query: 772 KNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVG 831
            N   +           RV P  K+++VE ++ + + +T   GDG ND   +K A IG+ 
Sbjct: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSF-DEITAMTGDGVNDAPALKKAEIGIA 718

Query: 832 ISGQEGLQAVLASDYSFAQFRYLQRLLLV-HGRWSYFRMCKFLCYFFYKNFAFTLVHFWF 890
           + G     A  AS+   A   +   +  V  GR  Y  M +F+ Y    N    +V  + 
Sbjct: 719 M-GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVG-EVVCIFL 776

Query: 891 GFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKP--GQLNL 948
               GF    +  Q  +   N+V   LP  A+G    D+   N        KP       
Sbjct: 777 TAALGFPEALIPVQ--LLWVNLVTDGLPATALGFNPPDLDIMN--------KPPRNPKEP 826

Query: 949 LFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQ 992
           L +   FF  +  G Y       +   A++ +A + G  ++ YQ
Sbjct: 827 LISGWLFFRYLAIGCYVGAAT--VGAAAWWFIAADGGPRVSFYQ 868


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,703,447
Number of Sequences: 37866
Number of extensions: 1693048
Number of successful extensions: 4640
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4318
Number of HSP's gapped (non-prelim): 169
length of query: 1192
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1078
effective length of database: 13,930,794
effective search space: 15017395932
effective search space used: 15017395932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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