Guide to the Human Genome
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Search of human proteins with 4885253

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885253 growth arrest-specific 2 [Homo sapiens]
         (313 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219842340 growth arrest-specific 2 [Homo sapiens]                  640   0.0  
gi|29540559 growth arrest-specific 2 [Homo sapiens]                   640   0.0  
gi|4885253 growth arrest-specific 2 [Homo sapiens]                    640   0.0  
gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens]            342   2e-94
gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]            199   3e-51
gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo sapi...   170   1e-42
gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo sapi...   170   1e-42
gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo sapi...   170   1e-42
gi|33188445 microfilament and actin filament cross-linker protei...    59   7e-09
gi|33188443 microfilament and actin filament cross-linker protei...    54   2e-07
gi|221316624 dystonin isoform 4 [Homo sapiens]                         53   4e-07
gi|221316622 dystonin isoform 3 [Homo sapiens]                         53   4e-07
gi|221316618 dystonin isoform 2 [Homo sapiens]                         53   4e-07
gi|34577047 dystonin isoform 1 [Homo sapiens]                          53   4e-07
gi|34577049 dystonin isoform 1eA precursor [Homo sapiens]              53   4e-07
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo...    39   0.008
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo...    39   0.008
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo...    39   0.008
gi|30181233 leucine-rich repeats and calponin homology (CH) doma...    38   0.013
gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]            33   0.43 
gi|22218339 hypothetical protein LOC90362 [Homo sapiens]               32   0.56 
gi|4758018 calponin 2 isoform a [Homo sapiens]                         32   0.73 
gi|29029632 anaplastic lymphoma kinase [Homo sapiens]                  31   1.2  
gi|5729734 activator of S phase kinase [Homo sapiens]                  30   2.1  
gi|124028529 symplekin [Homo sapiens]                                  30   2.1  
gi|41327730 calponin 2 isoform b [Homo sapiens]                        30   2.1  
gi|116812586 leucine zipper protein 5 [Homo sapiens]                   30   3.6  
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap...    29   4.7  
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap...    29   4.7  
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap...    29   4.7  

>gi|219842340 growth arrest-specific 2 [Homo sapiens]
          Length = 313

 Score =  640 bits (1650), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK 60
           MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK
Sbjct: 1   MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK 60

Query: 61  LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC 120
           LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC
Sbjct: 61  LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC 120

Query: 121 RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS 180
           RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS
Sbjct: 121 RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS 180

Query: 181 APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI 240
           APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI
Sbjct: 181 APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI 240

Query: 241 RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL 300
           RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL
Sbjct: 241 RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL 300

Query: 301 VVSASYKAKKEIK 313
           VVSASYKAKKEIK
Sbjct: 301 VVSASYKAKKEIK 313


>gi|29540559 growth arrest-specific 2 [Homo sapiens]
          Length = 313

 Score =  640 bits (1650), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK 60
           MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK
Sbjct: 1   MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK 60

Query: 61  LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC 120
           LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC
Sbjct: 61  LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC 120

Query: 121 RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS 180
           RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS
Sbjct: 121 RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS 180

Query: 181 APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI 240
           APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI
Sbjct: 181 APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI 240

Query: 241 RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL 300
           RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL
Sbjct: 241 RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL 300

Query: 301 VVSASYKAKKEIK 313
           VVSASYKAKKEIK
Sbjct: 301 VVSASYKAKKEIK 313


>gi|4885253 growth arrest-specific 2 [Homo sapiens]
          Length = 313

 Score =  640 bits (1650), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK 60
           MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK
Sbjct: 1   MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEK 60

Query: 61  LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC 120
           LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC
Sbjct: 61  LDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWC 120

Query: 121 RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS 180
           RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS
Sbjct: 121 RDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLS 180

Query: 181 APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI 240
           APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI
Sbjct: 181 APSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFI 240

Query: 241 RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL 300
           RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL
Sbjct: 241 RMLHNKHVMVRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQSKSPTLKDMNPDNYL 300

Query: 301 VVSASYKAKKEIK 313
           VVSASYKAKKEIK
Sbjct: 301 VVSASYKAKKEIK 313


>gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens]
          Length = 694

 Score =  342 bits (878), Expect = 2e-94
 Identities = 170/299 (56%), Positives = 215/299 (71%), Gaps = 15/299 (5%)

Query: 10  RSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQ 69
           R GPGL+++ QY +W+A RHEA LLPM+EDL++WL+ LLG ++ AE  +E+LDNG LLCQ
Sbjct: 24  RHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQ 83

Query: 70  LAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETC 129
           L + +Q   K     ++ + N P++K+PCK  A SGSFFARDNTANFL WCRD+GVDET 
Sbjct: 84  LIDVLQNMVKTCN--SEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETY 141

Query: 130 LFESEGLVLHKQPREVCLCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPS 189
           LFESEGLVLHK PR+V LCLLE+GRI +RYGVEPP L+KLEKEIE EETL   S  P  S
Sbjct: 142 LFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTS-GPEDS 200

Query: 190 SKSSGKKSTGNLLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEKILFIRMLHNKHVM 249
                       L +AVK I+EDPPC C ++F +E LS+GRYR+G+KILFIRMLH KHVM
Sbjct: 201 ISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVM 260

Query: 250 VRVGGGWETFAGYLLKHDPCRMLQISRVDGKTSPIQ------------SKSPTLKDMNP 296
           VRVGGGW+T  G+LLK+DPCR+LQ + ++ K    Q            +++P   +MNP
Sbjct: 261 VRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNP 319


>gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]
          Length = 880

 Score =  199 bits (505), Expect = 3e-51
 Identities = 112/258 (43%), Positives = 154/258 (59%), Gaps = 11/258 (4%)

Query: 30  EANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEK---FKESMDANK 86
           E  L  MKEDLA WL +L G +I A  F++ L+ G +LCQ A  + +    F     A  
Sbjct: 28  EQYLEAMKEDLAEWLRDLYGLDIDAANFLQVLETGLVLCQHANVVTDAALAFLAEAPAQA 87

Query: 87  PTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCR-DLGVDETCLFESEGLVLHKQPREV 145
               +P   + C  +A  G+F ARDN +NF+ WCR ++G+ E  +FE+E LVL K  + V
Sbjct: 88  QKIPMPRVGVSCNGAAQPGTFQARDNVSNFIQWCRKEMGIQEVLMFETEDLVLRKNVKNV 147

Query: 146 CLCLLELGRIAARYGVEPPGLIKLEKEIEQE--ETLSAPSPSPSPSSKSSGKKSTGNLLD 203
            LCLLELGR A R+GV  P L++LE+EIE+E    L+ P P PSP +    +      LD
Sbjct: 148 VLCLLELGRRAWRFGVAAPTLVQLEEEIEEEVRRELALPPPDPSPPAPPRRQPCHFRNLD 207

Query: 204 DAVKRISEDPPCKCPNKFCVERLSQGRYRVGEK--ILFIRMLHNKHVMVRVGGGWETFAG 261
             V+ +     C CP +F + ++S+G+YRVG+   ++FIR+L N HVMVRVGGGW+T   
Sbjct: 208 QMVQSLVSH--CTCPVQFSMVKVSEGKYRVGDSNTLIFIRILRN-HVMVRVGGGWDTLGH 264

Query: 262 YLLKHDPCRMLQISRVDG 279
           YL KHDPCR   +S   G
Sbjct: 265 YLDKHDPCRCTSLSHKPG 282


>gi|23065529 growth arrest-specific 2 like 1 isoform b [Homo
           sapiens]
          Length = 337

 Score =  170 bits (431), Expect = 1e-42
 Identities = 105/261 (40%), Positives = 152/261 (58%), Gaps = 28/261 (10%)

Query: 30  EANLLPMKEDLALWLTNLLGKEITA--ETFMEKLDNGALLCQLAETMQEKFKESMDANKP 87
           EA +  MKEDLA WL  L G  +    + F+  L  G  LCQ A  + E  + ++ A +P
Sbjct: 23  EAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAAR-ALAAARP 81

Query: 88  TKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCR-DLGVDETCLFESEGLVLHKQPREVC 146
            + +  +      S   GSF ARDN A F+ WCR +LGV E  +FE+E LVL K  + V 
Sbjct: 82  ARGVAFQA----HSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVV 137

Query: 147 LCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSP------------SPSPSSKSSG 194
           LCLLE+ R  AR G+  P L++ E+EIE+E   + P+P            +P+P + + G
Sbjct: 138 LCLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARG 197

Query: 195 KKSTGN---LLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEK--ILFIRMLHNKHVM 249
            + T +    LD+ V+ I     C CP++F + ++S+G+YRVG+   ++F+R+L + HVM
Sbjct: 198 PRMTPSDLRNLDELVREIL--GRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRS-HVM 254

Query: 250 VRVGGGWETFAGYLLKHDPCR 270
           VRVGGGW+T   YL KHDPCR
Sbjct: 255 VRVGGGWDTLEHYLDKHDPCR 275


>gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score =  170 bits (431), Expect = 1e-42
 Identities = 105/261 (40%), Positives = 152/261 (58%), Gaps = 28/261 (10%)

Query: 30  EANLLPMKEDLALWLTNLLGKEITA--ETFMEKLDNGALLCQLAETMQEKFKESMDANKP 87
           EA +  MKEDLA WL  L G  +    + F+  L  G  LCQ A  + E  + ++ A +P
Sbjct: 23  EAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAAR-ALAAARP 81

Query: 88  TKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCR-DLGVDETCLFESEGLVLHKQPREVC 146
            + +  +      S   GSF ARDN A F+ WCR +LGV E  +FE+E LVL K  + V 
Sbjct: 82  ARGVAFQA----HSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVV 137

Query: 147 LCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSP------------SPSPSSKSSG 194
           LCLLE+ R  AR G+  P L++ E+EIE+E   + P+P            +P+P + + G
Sbjct: 138 LCLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARG 197

Query: 195 KKSTGN---LLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEK--ILFIRMLHNKHVM 249
            + T +    LD+ V+ I     C CP++F + ++S+G+YRVG+   ++F+R+L + HVM
Sbjct: 198 PRMTPSDLRNLDELVREIL--GRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRS-HVM 254

Query: 250 VRVGGGWETFAGYLLKHDPCR 270
           VRVGGGW+T   YL KHDPCR
Sbjct: 255 VRVGGGWDTLEHYLDKHDPCR 275


>gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score =  170 bits (431), Expect = 1e-42
 Identities = 105/261 (40%), Positives = 152/261 (58%), Gaps = 28/261 (10%)

Query: 30  EANLLPMKEDLALWLTNLLGKEITA--ETFMEKLDNGALLCQLAETMQEKFKESMDANKP 87
           EA +  MKEDLA WL  L G  +    + F+  L  G  LCQ A  + E  + ++ A +P
Sbjct: 23  EAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAAR-ALAAARP 81

Query: 88  TKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCR-DLGVDETCLFESEGLVLHKQPREVC 146
            + +  +      S   GSF ARDN A F+ WCR +LGV E  +FE+E LVL K  + V 
Sbjct: 82  ARGVAFQA----HSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVV 137

Query: 147 LCLLELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSP------------SPSPSSKSSG 194
           LCLLE+ R  AR G+  P L++ E+EIE+E   + P+P            +P+P + + G
Sbjct: 138 LCLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARG 197

Query: 195 KKSTGN---LLDDAVKRISEDPPCKCPNKFCVERLSQGRYRVGEK--ILFIRMLHNKHVM 249
            + T +    LD+ V+ I     C CP++F + ++S+G+YRVG+   ++F+R+L + HVM
Sbjct: 198 PRMTPSDLRNLDELVREIL--GRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRS-HVM 254

Query: 250 VRVGGGWETFAGYLLKHDPCR 270
           VRVGGGW+T   YL KHDPCR
Sbjct: 255 VRVGGGWDTLEHYLDKHDPCR 275


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 27/70 (38%), Positives = 47/70 (67%), Gaps = 6/70 (8%)

Query: 203  DDAVKRISEDPPCKCPNKFCVERLSQGRYRVGE--KILFIRMLHNKHVMVRVGGGWETFA 260
            D+  +++++   CKC  +F VE++ + +YR G+  ++  +R+L +  VMVRVGGGW    
Sbjct: 5166 DEVTRQVAQ---CKCAKRFQVEQIGENKYRFGDSQQLRLVRILRST-VMVRVGGGWMALD 5221

Query: 261  GYLLKHDPCR 270
             +L+K+DPCR
Sbjct: 5222 EFLVKNDPCR 5231


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 12/76 (15%)

Query: 203  DDAVKRISEDPPCKCPNKFCVERLSQGRYRV--------GEKILFIRMLHNKHVMVRVGG 254
            D+  +++++   CKC  +F VE++ + +YR          +++  +R+L +  VMVRVGG
Sbjct: 5668 DEVTRQVAQ---CKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGG 5723

Query: 255  GWETFAGYLLKHDPCR 270
            GW     +L+K+DPCR
Sbjct: 5724 GWMALDEFLVKNDPCR 5739


>gi|221316624 dystonin isoform 4 [Homo sapiens]
          Length = 5526

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 26/76 (34%), Positives = 45/76 (59%), Gaps = 12/76 (15%)

Query: 203  DDAVKRISEDPPCKCPNKFCVERLSQGRYRV--------GEKILFIRMLHNKHVMVRVGG 254
            D+  +++++   CKC  +F VE++   +YR          +++  +R+L +  VMVRVGG
Sbjct: 5223 DEVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGG 5278

Query: 255  GWETFAGYLLKHDPCR 270
            GW     +L+K+DPCR
Sbjct: 5279 GWMALDEFLVKNDPCR 5294


>gi|221316622 dystonin isoform 3 [Homo sapiens]
          Length = 5537

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 26/76 (34%), Positives = 45/76 (59%), Gaps = 12/76 (15%)

Query: 203  DDAVKRISEDPPCKCPNKFCVERLSQGRYRV--------GEKILFIRMLHNKHVMVRVGG 254
            D+  +++++   CKC  +F VE++   +YR          +++  +R+L +  VMVRVGG
Sbjct: 5234 DEVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGG 5289

Query: 255  GWETFAGYLLKHDPCR 270
            GW     +L+K+DPCR
Sbjct: 5290 GWMALDEFLVKNDPCR 5305


>gi|221316618 dystonin isoform 2 [Homo sapiens]
          Length = 5675

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 26/76 (34%), Positives = 45/76 (59%), Gaps = 12/76 (15%)

Query: 203  DDAVKRISEDPPCKCPNKFCVERLSQGRYRV--------GEKILFIRMLHNKHVMVRVGG 254
            D+  +++++   CKC  +F VE++   +YR          +++  +R+L +  VMVRVGG
Sbjct: 5372 DEVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGG 5427

Query: 255  GWETFAGYLLKHDPCR 270
            GW     +L+K+DPCR
Sbjct: 5428 GWMALDEFLVKNDPCR 5443


>gi|34577047 dystonin isoform 1 [Homo sapiens]
          Length = 5497

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 26/76 (34%), Positives = 45/76 (59%), Gaps = 12/76 (15%)

Query: 203  DDAVKRISEDPPCKCPNKFCVERLSQGRYRV--------GEKILFIRMLHNKHVMVRVGG 254
            D+  +++++   CKC  +F VE++   +YR          +++  +R+L +  VMVRVGG
Sbjct: 5194 DEVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGG 5249

Query: 255  GWETFAGYLLKHDPCR 270
            GW     +L+K+DPCR
Sbjct: 5250 GWMALDEFLVKNDPCR 5265


>gi|34577049 dystonin isoform 1eA precursor [Homo sapiens]
          Length = 5171

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 26/76 (34%), Positives = 45/76 (59%), Gaps = 12/76 (15%)

Query: 203  DDAVKRISEDPPCKCPNKFCVERLSQGRYRV--------GEKILFIRMLHNKHVMVRVGG 254
            D+  +++++   CKC  +F VE++   +YR          +++  +R+L +  VMVRVGG
Sbjct: 4868 DEVTRQVAK---CKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRST-VMVRVGG 4923

Query: 255  GWETFAGYLLKHDPCR 270
            GW     +L+K+DPCR
Sbjct: 4924 GWMALDEFLVKNDPCR 4939


>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
           sapiens]
          Length = 1056

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 18/102 (17%)

Query: 35  PMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKNLPLK 94
           P   +   W+  + G+    + F   L+NG LLC+L           ++A KP     + 
Sbjct: 22  PAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCEL-----------LNAIKPGLVKKIN 70

Query: 95  KIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGL 136
           ++P   +         DN   FL  C++LG+ E+ LF+   L
Sbjct: 71  RLPTPIA-------GLDNIILFLRGCKELGLKESQLFDPSDL 105


>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
           sapiens]
          Length = 1057

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 18/102 (17%)

Query: 35  PMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKNLPLK 94
           P   +   W+  + G+    + F   L+NG LLC+L           ++A KP     + 
Sbjct: 22  PAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCEL-----------LNAIKPGLVKKIN 70

Query: 95  KIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGL 136
           ++P   +         DN   FL  C++LG+ E+ LF+   L
Sbjct: 71  RLPTPIA-------GLDNIILFLRGCKELGLKESQLFDPSDL 105


>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
           sapiens]
          Length = 1083

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 18/102 (17%)

Query: 35  PMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKNLPLK 94
           P   +   W+  + G+    + F   L+NG LLC+L           ++A KP     + 
Sbjct: 22  PAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCEL-----------LNAIKPGLVKKIN 70

Query: 95  KIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGL 136
           ++P   +         DN   FL  C++LG+ E+ LF+   L
Sbjct: 71  RLPTPIA-------GLDNIILFLRGCKELGLKESQLFDPSDL 105


>gi|30181233 leucine-rich repeats and calponin homology (CH) domain
           containing 4 [Homo sapiens]
          Length = 683

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 15/107 (14%)

Query: 34  LPMKEDLALWLTNLLGKEITA---ETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKN 90
           +P ++DL   L  +L   +     E   E L +G +LCQLA  ++ +            +
Sbjct: 534 VPDEKDLMTQLRQVLESRLQRPLPEDLAEALASGVILCQLANQLRPR------------S 581

Query: 91  LPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLV 137
           +P   +P        +  AR N  +FL  CR +GV E  L     L+
Sbjct: 582 VPFIHVPSPAVPKLSALKARKNVESFLEACRKMGVPEADLCSPSDLL 628


>gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]
          Length = 297

 Score = 32.7 bits (73), Expect = 0.43
 Identities = 28/124 (22%), Positives = 51/124 (41%), Gaps = 19/124 (15%)

Query: 37  KEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKI 96
           +++L  W+  + G+ I    FM+ L +G +LC+    +Q    + +  N+ T+N      
Sbjct: 31  EQELREWIEGVTGRRI-GNNFMDGLKDGIILCEFINKLQPGSVKKI--NESTQN------ 81

Query: 97  PCKTSAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLLELGRIA 156
                     +   +N  NF+      GV    +FE+  L  +    +V   LL L  +A
Sbjct: 82  ----------WHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMA 131

Query: 157 ARYG 160
              G
Sbjct: 132 KTKG 135


>gi|22218339 hypothetical protein LOC90362 [Homo sapiens]
          Length = 370

 Score = 32.3 bits (72), Expect = 0.56
 Identities = 18/38 (47%), Positives = 20/38 (52%)

Query: 66  LLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAP 103
           LL Q AE+       S D  K T   PLK IPC +SAP
Sbjct: 185 LLEQSAESFLHVSHSSSDIRKVTSVKPLKAIPCSSSAP 222


>gi|4758018 calponin 2 isoform a [Homo sapiens]
          Length = 309

 Score = 32.0 bits (71), Expect = 0.73
 Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 24/158 (15%)

Query: 6   SPKVRSGPGLSDMHQYSQWLASRHEANLLPMKE-DLALWLTNLLGKEITAETFMEKLDNG 64
           S +   GP      +    L S+++    P KE +L  W+  L G  I  + F + L +G
Sbjct: 3   STQFNKGPSYGLSAEVKNRLLSKYD----PQKEAELRTWIEGLTGLSIGPD-FQKGLKDG 57

Query: 65  ALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLG 124
            +LC L   +Q                    +P K +    ++   +N +NF+      G
Sbjct: 58  TILCTLMNKLQPG-----------------SVP-KINRSMQNWHQLENLSNFIKAMVSYG 99

Query: 125 VDETCLFESEGLVLHKQPREVCLCLLELGRIAARYGVE 162
           ++   LFE+  L       +V + LL L   A   G++
Sbjct: 100 MNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQ 137


>gi|29029632 anaplastic lymphoma kinase [Homo sapiens]
          Length = 1620

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 16/46 (34%), Positives = 25/46 (54%)

Query: 163  PPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKR 208
            PP L+  + + E+E + +AP P P+ SS  + KK T   +   V R
Sbjct: 1422 PPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPR 1467


>gi|5729734 activator of S phase kinase [Homo sapiens]
          Length = 674

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 21/73 (28%), Positives = 32/73 (43%)

Query: 153 GRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSPSSKSSGKKSTGNLLDDAVKRISED 212
           GR+      +   LI  +KE +  +TL   SP PSP S  + + ++ +   D     S D
Sbjct: 73  GRVEEFLSKDISYLISNKKEAKFAQTLGRISPVPSPESAYTAETTSPHPSHDGSSFKSPD 132

Query: 213 PPCKCPNKFCVER 225
             C    K  VE+
Sbjct: 133 TVCLSRGKLLVEK 145


>gi|124028529 symplekin [Homo sapiens]
          Length = 1274

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 13/61 (21%)

Query: 169  LEKEIEQEETL--------SAPSPSPSPSSKSSGKKSTGNLLDDAVKRISEDPPCKCPNK 220
            L++++E+E+ L        S+ SPSPSPS++     S     ++A+    E P C+ P  
Sbjct: 1149 LKRQLEEEQKLKPGGVGAPSSSSPSPSPSARPGPPPS-----EEAMDFREEGPECETPGI 1203

Query: 221  F 221
            F
Sbjct: 1204 F 1204


>gi|41327730 calponin 2 isoform b [Homo sapiens]
          Length = 270

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 24/148 (16%)

Query: 6   SPKVRSGPGLSDMHQYSQWLASRHEANLLPMKE-DLALWLTNLLGKEITAETFMEKLDNG 64
           S +   GP      +    L S+++    P KE +L  W+  L G  I  + F + L +G
Sbjct: 3   STQFNKGPSYGLSAEVKNRLLSKYD----PQKEAELRTWIEGLTGLSIGPD-FQKGLKDG 57

Query: 65  ALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFARDNTANFLSWCRDLG 124
            +LC L   +Q                    +P K +    ++   +N +NF+      G
Sbjct: 58  TILCTLMNKLQPG-----------------SVP-KINRSMQNWHQLENLSNFIKAMVSYG 99

Query: 125 VDETCLFESEGLVLHKQPREVCLCLLEL 152
           ++   LFE+  L       +V + LL L
Sbjct: 100 MNPVDLFEANDLFESGNMTQVQVSLLAL 127


>gi|116812586 leucine zipper protein 5 [Homo sapiens]
          Length = 1143

 Score = 29.6 bits (65), Expect = 3.6
 Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 14  GLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAET 73
           GL D HQ+   L  R    +  +K    + L   + KEIT  + ++K D+   +  L +T
Sbjct: 895 GLGD-HQFQMQLLQRSLGIMQTVKGFFYVSLLLDILKEITGSSLIQKTDSDEEVAMLLDT 953

Query: 74  MQEKFKESMD 83
           +Q+ F++ ++
Sbjct: 954 VQKVFQKMLE 963


>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
           sapiens]
          Length = 436

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 25  LASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDA 84
           L+ R EA  L   + L+  L NL G+ +TA T  EKL+         +T+ E F +   A
Sbjct: 110 LSEREEA--LKQHKTLSQELVNLRGELVTASTTCEKLEKAR---NELQTVYEAFVQQHQA 164

Query: 85  NKPTKNLPLKK 95
            K  +   LK+
Sbjct: 165 EKTERENRLKE 175


>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
          Length = 1270

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 25   LASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDA 84
            L+ R EA  L   + L+  L NL G+ +TA T  EKL+         +T+ E F +   A
Sbjct: 944  LSEREEA--LKQHKTLSQELVNLRGELVTASTTCEKLEKAR---NELQTVYEAFVQQHQA 998

Query: 85   NKPTKNLPLKK 95
             K  +   LK+
Sbjct: 999  EKTERENRLKE 1009


>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo
           sapiens]
          Length = 1216

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 25  LASRHEANLLPMKEDLALWLTNLLGKEITAETFMEKLDNGALLCQLAETMQEKFKESMDA 84
           L+ R EA  L   + L+  L NL G+ +TA T  EKL+         +T+ E F +   A
Sbjct: 890 LSEREEA--LKQHKTLSQELVNLRGELVTASTTCEKLEKAR---NELQTVYEAFVQQHQA 944

Query: 85  NKPTKNLPLKK 95
            K  +   LK+
Sbjct: 945 EKTERENRLKE 955


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,432,552
Number of Sequences: 37866
Number of extensions: 653177
Number of successful extensions: 3136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3075
Number of HSP's gapped (non-prelim): 43
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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